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Search of human proteins with 156119625
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
(911 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens] 1824 0.0
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [... 948 0.0
gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo ... 624 e-178
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens] 481 e-135
gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor... 434 e-121
gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor... 379 e-105
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens] 331 2e-90
gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor ... 317 2e-86
gi|194306644 BCSC-1 isoform 1 [Homo sapiens] 67 6e-11
gi|38195080 BCSC-1 isoform 1 [Homo sapiens] 67 6e-11
gi|210147462 von Willebrand factor A domain containing 5B1 [Homo... 63 1e-09
gi|38195082 BCSC-1 isoform 2 [Homo sapiens] 62 3e-09
gi|54112394 calcium channel, voltage-dependent, alpha 2/delta su... 52 2e-06
gi|54112392 calcium channel, voltage-dependent, alpha 2/delta su... 52 2e-06
gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subun... 50 7e-06
gi|54112390 calcium channel, voltage-dependent, alpha 2/delta su... 47 1e-04
gi|118918435 von Willebrand factor A domain containing 3B [Homo ... 45 3e-04
gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3 ... 44 7e-04
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo... 44 9e-04
gi|218505703 von Willebrand factor A domain containing 3A [Homo ... 43 0.002
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 34 0.54
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 34 0.54
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 34 0.54
gi|13654239 WW domain containing E3 ubiquitin protein ligase 1 [... 32 3.5
gi|211971038 tousled-like kinase 1 isoform 3 [Homo sapiens] 32 3.5
gi|211971036 tousled-like kinase 1 isoform 2 [Homo sapiens] 32 3.5
gi|33636698 tousled-like kinase 1 isoform 1 [Homo sapiens] 32 3.5
gi|11321565 matrilin 3 precursor [Homo sapiens] 31 4.6
gi|190684671 mitogen-activated protein kinase binding protein 1 ... 31 6.0
gi|190684677 mitogen-activated protein kinase binding protein 1 ... 31 6.0
>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
Length = 911
Score = 1824 bits (4725), Expect = 0.0
Identities = 911/911 (100%), Positives = 911/911 (100%)
Query: 1 MDGAMGPRGLLLCMYLVSLLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNC 60
MDGAMGPRGLLLCMYLVSLLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNC
Sbjct: 1 MDGAMGPRGLLLCMYLVSLLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNC 60
Query: 61 KVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAW 120
KVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAW
Sbjct: 61 KVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAW 120
Query: 121 KQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIK 180
KQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIK
Sbjct: 121 KQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIK 180
Query: 181 VKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQ 240
VKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQ
Sbjct: 181 VKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQ 240
Query: 241 QQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDIS 300
QQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDIS
Sbjct: 241 QQSCPTCSTSLLNGHFKVTYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDIS 300
Query: 301 GSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVR 360
GSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVR
Sbjct: 301 GSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVR 360
Query: 361 GFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNV 420
GFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNV
Sbjct: 361 GFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNV 420
Query: 421 RNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLL 480
RNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLL
Sbjct: 421 RNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLL 480
Query: 481 VDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITC 540
VDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITC
Sbjct: 481 VDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITC 540
Query: 541 LVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDY 600
LVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDY
Sbjct: 541 LVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDY 600
Query: 601 GFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQ 660
GFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQ
Sbjct: 601 GFVTPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQ 660
Query: 661 RLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKAR 720
RLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKAR
Sbjct: 661 RLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKAR 720
Query: 721 SPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTIN 780
SPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTIN
Sbjct: 721 SPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTIN 780
Query: 781 KKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGF 840
KKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGF
Sbjct: 781 KKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGF 840
Query: 841 EVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDG 900
EVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDG
Sbjct: 841 EVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDG 900
Query: 901 AYTDYIVPDIF 911
AYTDYIVPDIF
Sbjct: 901 AYTDYIVPDIF 911
>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
[Homo sapiens]
Length = 890
Score = 948 bits (2450), Expect = 0.0
Identities = 487/896 (54%), Positives = 638/896 (71%), Gaps = 19/896 (2%)
Query: 19 LLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNT 78
L +L ++ A G + KR + +G+ + S K+N KVTSRFAH VVT + VN
Sbjct: 11 LALLSSLAASGFPRSPFRLLGKRSLPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNR 70
Query: 79 ANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRA 138
A+ A+EV+FD+E+PKTAFI++F +T DG + G++K+K A KQY KA G+ AGLV+A
Sbjct: 71 ADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGKTAGLVKA 130
Query: 139 SGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFE 198
SGR +E+FT+ + V SKVTF+LTYEE+LKR+ +YE+ +KV+PKQLV HFEI+VDIFE
Sbjct: 131 SGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEIEVDIFE 190
Query: 199 PQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKV 258
PQGIS LDA+ASF+ +L + KSFSGKKGHV F+P++ QQ+SCPTC+ SLLNG F +
Sbjct: 191 PQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTI 250
Query: 259 TYDVSRDKICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKI 318
TYDV+R+ ++ + N +F HFFAPQ L + KNV FVIDISGSM G+K++QTKEALL+I
Sbjct: 251 TYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKNVAFVIDISGSMAGRKLEQTKEALLRI 310
Query: 319 LGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGI 378
L DMQ DY + +LF V +WK LVQA+ NLQ A+ FV+ TN+N GLLRGI
Sbjct: 311 LEDMQEEDYLNFILFSGDVSTWKEHLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGI 370
Query: 379 EILNQVQES--LPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFG 436
+LN+ +E +PE S SI+IMLTDGD G + +I +NVRNAI G+FPLYNLGFG
Sbjct: 371 SMLNKAREEHRIPERST--SIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFG 428
Query: 437 HNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALT 496
+N+++NFLE M++EN+G A+RIYED DA QLQGFY +VA PLL V+++YP++A+L LT
Sbjct: 429 NNLNYNFLENMALENHGFARRIYEDSDADLQLQGFYEEVANPLLTGVEMEYPENAILDLT 488
Query: 497 QNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGH 556
QN ++ +Y+GSEIVVAGR+ D +SFKADV+ HG + + T VD +EM+K L+ER +
Sbjct: 489 QNTYQHFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEVDMKEMEKALQERDY 548
Query: 557 MLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMAD 616
+ N++ERLWAYLTI++LL KR EE+ NL+++AL +SL Y FVTPLTSM + D
Sbjct: 549 IFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTARALDLSLKYHFVTPLTSMVVTKPED 608
Query: 617 QDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFI 676
+ + DKP ED+ + P +++ S P + VD DPHFI
Sbjct: 609 NEDERAIADKPGEDAEATP-VSPAMSYLTSYQPPQNPYYY------------VDGDPHFI 655
Query: 677 IHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSP-GQHDGTYFGRLGI 735
I +P+K+D LCFNI+E PG +L L+QD TG +VNGQ+ G+K SP + TYFG+LGI
Sbjct: 656 IQIPEKDDALCFNIDEAPGTVLRLIQDAVTGLTVNGQITGDKRGSPDSKTRKTYFGKLGI 715
Query: 736 ANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTF 795
AN DFQ+EVT + ITL FSW D + QDG+ + IN+K N+VVS DG TF
Sbjct: 716 ANAQMDFQVEVTTEKITLWNRAVPSTFSWLDTVTVTQDGLSMMINRK-NMVVSFGDGVTF 774
Query: 796 EVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPD 855
VVLH+VWK VH+DFLGFYV+DSHRMSA+THGLLGQFF P F+VSDI PGSDPTKPD
Sbjct: 775 VVVLHQVWKKHPVHRDFLGFYVVDSHRMSAQTHGLLGQFFQPFDFKVSDIRPGSDPTKPD 834
Query: 856 ATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF 911
AT+VV+N +L VTRG QKDY KD G +V CWF+HNNG GLIDG +TDYIVP++F
Sbjct: 835 ATLVVKNHQLIVTRGSQKDYRKDASIGTKVVCWFVHNNGEGLIDGVHTDYIVPNLF 890
>gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo
sapiens]
Length = 946
Score = 624 bits (1609), Expect = e-178
Identities = 350/895 (39%), Positives = 518/895 (57%), Gaps = 25/895 (2%)
Query: 34 RSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPK 93
RS E + ++ VD V + S KV +TSR A ++ S+VVN + + + V FD++IPK
Sbjct: 54 RSLPGESEEMMEE-VDQVTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPK 112
Query: 94 TAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVN 153
AFIS+F++T DG F IK+K Y +A G+ AGLVR+S ME F + V
Sbjct: 113 GAFISNFSMTVDGKTFRSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVL 172
Query: 154 PQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLP 213
P +KV F+L Y+EV R YE I ++P +L H E+DV + EPQG+ L +F
Sbjct: 173 PGAKVQFELHYQEVKWRKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEG 232
Query: 214 KELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRD-KICDLLV 272
I K +K HV F+PTV+QQ+ CP C + ++G V YDV R+ K +L V
Sbjct: 233 HFDGVPVISKG--QQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEV 290
Query: 273 ANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVL 332
N +F HFFAP NL + KN++FVID+SGSM G K+KQT EA+ IL D++ D+F ++
Sbjct: 291 FNGYFVHFFAPDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVID 350
Query: 333 FGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELS 392
F +++W+ L+ A++ + A+ ++ TN+N LLR I ILN+
Sbjct: 351 FNQNIRTWRNDLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDP 410
Query: 393 NHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENN 452
N S++I+++DGDPT G S+I KNV+ I+ L++LG G +VD++FL+ +S EN+
Sbjct: 411 NSVSLIILVSDGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENH 470
Query: 453 GRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVA 512
G AQRIY + D + QL+ FY+QV+ PLL +V YP +V +TQN+ Y+ GSEIVVA
Sbjct: 471 GIAQRIYGNQDTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVA 530
Query: 513 GRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQ 572
G+ K ++ + A + + L ++++ L + H + +LWAYLTI
Sbjct: 531 GKFDPAKLDQIESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTIN 590
Query: 573 ELLAKR-MKVDREERANLSSQALQMSLDYGFVTPLTSMSI-------RGMADQDGLKPTI 624
+LLA+R + + ++ LQMSLD+ VTPLTS+ I R +AD P+
Sbjct: 591 QLLAERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPSC 650
Query: 625 --------DKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFI 676
K DS P P T V+S L S P V V+ DPHFI
Sbjct: 651 CSGALYYGSKVVPDSTP-SWANPSPTPVISMLAQGSQVLESTP---PPHVMRVENDPHFI 706
Query: 677 IHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIA 736
I++P+ + +CFNI+ EPG IL+LV DP +G VNGQL+G K + G+ TYFG+LG
Sbjct: 707 IYLPKSQKNICFNIDSEPGKILNLVSDPESGIVVNGQLVGAKKPNNGKLS-TYFGKLGFY 765
Query: 737 NPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFE 796
+ D ++E++ + ITL+ G SW D A + V +++ K++ + +++D +F
Sbjct: 766 FQSEDIKIEISTETITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFS 825
Query: 797 VVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDA 856
V+LHRVWK V+ DFLG Y+ +++ S + HGL+GQF + + PG DP KP+A
Sbjct: 826 VLLHRVWKKHPVNVDFLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPEA 885
Query: 857 TMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF 911
+M V+ ++L +TRGLQKDY D G +V+CWF+HN+G G IDG Y DY VP ++
Sbjct: 886 SMEVKGQKLIITRGLQKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDYFVPQLY 940
>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
Length = 930
Score = 481 bits (1238), Expect = e-135
Identities = 272/658 (41%), Positives = 394/658 (59%), Gaps = 26/658 (3%)
Query: 7 PRGLLLCMYLVSLLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRF 66
PR + C ++ LL L A+ Q +G+ I SL V+ +V+SRF
Sbjct: 4 PRPVRTCSKVLVLLSLLAI---------------HQTTTAEKNGIDIYSLTVDSRVSSRF 48
Query: 67 AHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAWKQYRKA 126
AH VVTS+VVN AN +E F +E+PK AFI++F++ DG + G IK+K A QY A
Sbjct: 49 AHTVVTSRVVNRANTVQEATFQMELPKKAFITNFSMIIDGMTYPGIIKEKAEAQAQYSAA 108
Query: 127 AISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQL 186
G++AGLV+A+GR MEQF + ++V P +K+TF+L YEE+LKR YE+++KV+P+QL
Sbjct: 109 VAKGKSAGLVKATGRNMEQFQVSVSVAPNAKITFELVYEELLKRRLGVYELLLKVRPQQL 168
Query: 187 VHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPT 246
V H ++D+ IFEPQGIS L+ +++F+ +L + + K H+ F+PT+SQQQ P
Sbjct: 169 VKHLQMDIHIFEPQGISFLETESTFMTNQLV-DALTTWQNKTKAHIRFKPTLSQQQKSPE 227
Query: 247 CSTSLLNGHFKVTYDVSRD-KICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRG 305
++L+G+ + YDV R + + N +F H+FAP+ LT M KNVVFVID SGSM G
Sbjct: 228 QQETVLDGNLIIRYDVDRAISGGSIQIENGYFVHYFAPEGLTTMPKNVVFVIDKSGSMSG 287
Query: 306 QKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLD 365
+K++QT+EAL+KIL D+ P D F+L++F T W+ SLV AS N+ A+ F G
Sbjct: 288 RKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPSLVPASAENVNKARSFAAGIQAL 347
Query: 366 EATNLNGGLLRGIEILNQV--QESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNA 423
TN+N +L +++L+ +E LPE S S++I+LTDGDPT G T+ I NVR A
Sbjct: 348 GGTNINDAMLMAVQLLDSSNQEERLPEGS--VSLIILLTDGDPTVGETNPRSIQNNVREA 405
Query: 424 IRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDV 483
+ GR+ L+ LGFG +V + FLE ++++N G A+RI+ED D+ QLQ FY +VA PLL V
Sbjct: 406 VSGRYSLFCLGFGFDVSYAFLEKLALDNGGLARRIHEDSDSALQLQDFYQEVANPLLTAV 465
Query: 484 DLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVD 543
+YP +AV +TQN+ + ++GSE+VVAG++ D A V Q +
Sbjct: 466 TFEYPSNAVEEVTQNNFRLLFKGSEMVVAGKLQDRGPDVLTATVSGKLPTQNITFQTESS 525
Query: 544 EEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFV 603
E + + ++ N +ERLWAYLTIQ+LL + + ++ L +QAL +SL Y FV
Sbjct: 526 VAEQEAEFQSPKYIFHNFMERLWAYLTIQQLLEQTVSASDADQQALRNQALNLSLAYSFV 585
Query: 604 TPLTSMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQ----PSPTHSSS 657
TPLTSM + DQ+ +KP E + TF LQ P P S S
Sbjct: 586 TPLTSMVVTKPDDQE-QSQVAEKPMEGESRNRNVHSGSTFFKYYLQGAKIPKPEASFS 642
Score = 56.6 bits (135), Expect = 1e-07
Identities = 54/221 (24%), Positives = 94/221 (42%), Gaps = 27/221 (12%)
Query: 673 PHFIIHVP-QKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFG 731
P I+ +P Q + LC + G + +L+ DP G V GQ KA G +
Sbjct: 732 PSAILPLPGQSVERLCVDPRHRQGPV-NLLSDPEQGVEVTGQYEREKA-------GFSWI 783
Query: 732 RLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDD 791
+ NP + +P+++ + + W++ G+ +T++K L++S D
Sbjct: 784 EVTFKNPLV--WVHASPEHVVVTRNRRSSAYKWKETLFSVMPGLKMTMDKTGLLLLSDPD 841
Query: 792 GGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDP 851
T ++ W G + L + D+ R S+ G LGQF+ + + GS
Sbjct: 842 KVTIGLLF---WDGRG---EGLRLLLRDTDRFSSHVGGTLGQFYQEVLW-------GSPA 888
Query: 852 TKPDA--TMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFI 890
D T+ V+ + TR + DY + P G E+SCW +
Sbjct: 889 ASDDGRRTLRVQGNDHSATRERRLDYQEGP-PGVEISCWSV 928
>gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 1 [Homo sapiens]
Length = 956
Score = 434 bits (1116), Expect = e-121
Identities = 284/888 (31%), Positives = 454/888 (51%), Gaps = 59/888 (6%)
Query: 58 VNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKV 117
V + SR+A V+ +++N A+E +++ F ++IP AFI++F + + G+I ++
Sbjct: 56 VKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITERE 115
Query: 118 TAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEI 177
K+ N + E F + + K F L+YEE+L+R +YE
Sbjct: 116 ---KKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEH 172
Query: 178 VIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKG------- 230
I V+P+QL +DV+I E GI+ L+ LP + Q G
Sbjct: 173 SISVRPQQLSGRLSVDVNILESAGIASLEV----LPLHNSRQRGSGRGEDDSGPPPSTVI 228
Query: 231 -------HVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDK-ICDLLVANNHFAHFFA 282
+++F+PTV QQ + + + G F + YDV+R++ I D+ V N +F H+FA
Sbjct: 229 NQNETFANIIFKPTVVQQARI---AQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFA 285
Query: 283 PQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKG 342
P++L + KNVVFV+D S SM G K++QTK+AL IL D++P D F ++ F R++ WK
Sbjct: 286 PKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKD 345
Query: 343 SLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLT 402
L+ + +++ + ++ S T++NG L R I +LN+ S+++ LT
Sbjct: 346 HLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLT 405
Query: 403 DGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDH 462
DG PT G T +IL N R A RG+ ++ +G G++VDF LE +S+EN G +R++E+
Sbjct: 406 DGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEE 465
Query: 463 DATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSS 522
DA QL GFY ++ PLL D+ + YP +V+ T+ Y+ GSEI++AG++ D K
Sbjct: 466 DAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDH 525
Query: 523 FKADVQAHGEGQEFSITCLVDEEEMKKLLRE---------RGHMLENHVERLWAYLTIQE 573
+V A ++F I +K ++ G NH+ERLW+YLT +E
Sbjct: 526 LHVEVTA-SNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKE 584
Query: 574 LLAKRMKVDRE-ERANLSSQALQMSLDYGFVTPLTSMSIRG-MADQDGLKPTIDKPSEDS 631
LL+ ++ D E E+ L +A +++ Y F+TP TSM +RG + DGL+ +
Sbjct: 585 LLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMG 644
Query: 632 PPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNIN 691
P + R + QP P R+ T VD DPHF++ P T+CFNI+
Sbjct: 645 PEPVVQSVRG----AGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLTVCFNID 700
Query: 692 EEPGVILSLVQD-PNTGFSVNGQLIGNKARSPG-QHDGTYFGRLGI-ANPATDFQLEVTP 748
+PG IL LV D ++G +VNG+LIG A G + TY + I N LE+TP
Sbjct: 701 GQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERSYLEITP 760
Query: 749 QNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSV 808
+ L+ G V V+ G+ V+++ N+ V++ F +++H K +
Sbjct: 761 SRVILDGG-DRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYKKPAPF 819
Query: 809 HQDFLGFYVLDSHRMSARTHGLLGQFFH--------PIGFEVSDIHP--GSDPTKPDATM 858
+ LGFY+ +S +S+ HGLLGQF + P G + HP P+A +
Sbjct: 820 QRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEGPEAVL 879
Query: 859 VVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYI 906
V+ ++ V +K Y+ + ++ CWF NN A LIDG Y DY+
Sbjct: 880 TVKGHQVPVVWKQRKIYNGE----EQIDCWFARNNAAKLIDGEYKDYL 923
>gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 2 [Homo sapiens]
Length = 742
Score = 379 bits (973), Expect = e-105
Identities = 237/701 (33%), Positives = 373/701 (53%), Gaps = 38/701 (5%)
Query: 231 HVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDK-ICDLLVANNHFAHFFAPQNLTNM 289
+++F+PTV QQ + + + G F + YDV+R++ I D+ V N +F H+FAP++L +
Sbjct: 22 NIIFKPTVVQQARI---AQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAPKDLPPL 78
Query: 290 NKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASE 349
KNVVFV+D S SM G K++QTK+AL IL D++P D F ++ F R++ WK L+ +
Sbjct: 79 PKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTP 138
Query: 350 ANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTEG 409
+++ + ++ S T++NG L R I +LN+ S+++ LTDG PT G
Sbjct: 139 DSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKPTVG 198
Query: 410 VTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQ 469
T +IL N R A RG+ ++ +G G++VDF LE +S+EN G +R++E+ DA QL
Sbjct: 199 ETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEEDAGSQLI 258
Query: 470 GFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQA 529
GFY ++ PLL D+ + YP +V+ T+ Y+ GSEI++AG++ D K +V A
Sbjct: 259 GFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHLHVEVTA 318
Query: 530 HGEGQEFSITCLVDEEEMKKLLRE---------RGHMLENHVERLWAYLTIQELLAKRMK 580
++F I +K ++ G NH+ERLW+YLT +ELL+ ++
Sbjct: 319 -SNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELLSSWLQ 377
Query: 581 VDRE-ERANLSSQALQMSLDYGFVTPLTSMSIRG-MADQDGLKPTIDKPSEDSPPLEMLG 638
D E E+ L +A +++ Y F+TP TSM +RG + DGL+ + P +
Sbjct: 378 SDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAAMGPEPVVQS 437
Query: 639 PRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVIL 698
R + QP P R+ T VD DPHF++ P T+CFNI+ +PG IL
Sbjct: 438 VRG----AGTQPGPLLKKPYQPRIKISKTSVDGDPHFVVDFPLSRLTVCFNIDGQPGDIL 493
Query: 699 SLVQD-PNTGFSVNGQLIGNKARSPG-QHDGTYFGRLGI-ANPATDFQLEVTPQNITLNP 755
LV D ++G +VNG+LIG A G + TY + I N LE+TP + L+
Sbjct: 494 RLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPERSYLEITPSRVILDG 553
Query: 756 GFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGF 815
G V V+ G+ V+++ N+ V++ F +++H K + + LGF
Sbjct: 554 G-DRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIHLYKKPAPFQRHHLGF 612
Query: 816 YVLDSHRMSARTHGLLGQFFH--------PIGFEVSDIHP--GSDPTKPDATMVVRNRRL 865
Y+ +S +S+ HGLLGQF + P G + HP P+A + V+ ++
Sbjct: 613 YIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQVGEGPEAVLTVKGHQV 672
Query: 866 TVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYI 906
V +K Y+ + ++ CWF NN A LIDG Y DY+
Sbjct: 673 PVVWKQRKIYNGE----EQIDCWFARNNAAKLIDGEYKDYL 709
>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
Length = 1313
Score = 331 bits (849), Expect = 2e-90
Identities = 214/579 (36%), Positives = 315/579 (54%), Gaps = 25/579 (4%)
Query: 51 VFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFI 110
+ + S + V SR+AH +VTS + N EA E FDL++P AFIS+F +T + +I
Sbjct: 35 LLMTSYSMRSTVVSRYAHTLVTSVLFNPHAEAHEAIFDLDLPHLAFISNFTMTINNKVYI 94
Query: 111 GDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKR 170
++K+K A K Y +A G+ A V R E+F I ++ ++VTF L YEE+L+R
Sbjct: 95 AEVKEKHQAKKIYEEAHQQGKTAAHVGIRDRESEKFRISTSLAAGTEVTFSLAYEELLQR 154
Query: 171 NHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDA---QASFLPKELAAQTIKKSFSG 227
+ QY++V+ ++P QLV I+V + E GIS + + L A + S
Sbjct: 155 HQGQYQLVVSLRPGQLVKRLSIEVTVSERTGISYVHIPPLRTGRLRTNAHASEVDSPPST 214
Query: 228 K--KGHVLFR----PTVSQQQSCPTCSTSLLNGHFKVTYDV-SRDKICDLLVANNHFAHF 280
+ +G R PT+ Q S S S + F V YDV D I D+ + +++F H+
Sbjct: 215 RIERGETCVRITYCPTLQDQSSI---SGSGIMADFLVQYDVVMEDIIGDVQIYDDYFIHY 271
Query: 281 FAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSW 340
FAP+ L M KNVVFVID+S SM G K++QTK A+ IL D+Q DYF+++ F V W
Sbjct: 272 FAPRGLPPMEKNVVFVIDVSSSMFGTKMEQTKTAMNVILSDLQANDYFNIISFSDTVNVW 331
Query: 341 K-GSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESL---PELSNHAS 396
K G +QA+ N+ +A+D++ D T++N LL +LN + P +
Sbjct: 332 KAGGSIQATIQNVHSAKDYLHCMEADGWTDVNSALLAAASVLNHSNQEPGRGPSVGR-IP 390
Query: 397 ILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQ 456
++I LTDG+PT GVT S IL NVR A+ R L++L FG + DF L +S+EN G A+
Sbjct: 391 LIIFLTDGEPTAGVTTPSVILSNVRQALGHRVSLFSLAFGDDADFTLLRRLSLENRGIAR 450
Query: 457 RIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIA 516
RIYED DA QL+G Y +++ PLL DV L Y V A Y+ GSE+VVAG++
Sbjct: 451 RIYEDTDAALQLKGLYEEISMPLLADVRLNYLGGLVGASPWAVFPNYFGGSELVVAGQVQ 510
Query: 517 DNKQSSFKADVQAHGEGQEFSIT-----CLVDEEEMKKLLRERGHMLENHVERLWAYLTI 571
KQ + A G + + + ++ E + + + RLWAY+TI
Sbjct: 511 PGKQ-ELGIHLAARGPKDQLLVAHHSEGATNNSQKAFGCPGEPAPNVAHFIRRLWAYVTI 569
Query: 572 QELLAKRMKV-DREERANLSSQALQMSLDYGFVTPLTSM 609
ELL + D R L+++ L +SL+Y FVTPLTS+
Sbjct: 570 GELLDAHFQARDTTTRHLLAAKVLNLSLEYNFVTPLTSL 608
Score = 96.3 bits (238), Expect = 1e-19
Identities = 71/253 (28%), Positives = 119/253 (47%), Gaps = 29/253 (11%)
Query: 667 TGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHD 726
+ VD DPHF+I +P E+ +CF +N PG +L L++DP G V+G+L+G R PG D
Sbjct: 1078 SSVDGDPHFVIQIPHSEEKICFTLNGHPGDLLQLIEDPKAGLHVSGKLLGAPPR-PGHKD 1136
Query: 727 --GTYFGRLGI-ANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKR 783
TYF + + + + + ++ +I+L G G SW A+L++ + + +
Sbjct: 1137 QTRTYFQIITVTTDKPRAYTITISRSSISLR-GEGTLRLSWDQPALLKRPQLELYVAAAA 1195
Query: 784 NLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVS 843
L + + F V+ HR S++ LGFYV + +S GL+GQF H +
Sbjct: 1196 RLTLRLGPYLEFLVLRHRYRHPSTLQLPHLGFYVANGSGLSPSARGLIGQFQH------A 1249
Query: 844 DIHPGSDPT--------KPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGA 895
DI + P PD +++ R L + L ++ SCW + +
Sbjct: 1250 DIRLVTGPMGPCLRRHHGPDVPVILGKRLLKDSPRLLPRWA---------SCWLVKRSHV 1300
Query: 896 GLIDG-AYTDYIV 907
L+ G Y Y++
Sbjct: 1301 ELLLGHPYLSYVL 1313
>gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 3 [Homo sapiens]
Length = 702
Score = 317 bits (813), Expect = 2e-86
Identities = 194/590 (32%), Positives = 316/590 (53%), Gaps = 37/590 (6%)
Query: 58 VNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKV 117
V + SR+A V+ +++N A+E +++ F ++IP AFI++F + + G+I ++
Sbjct: 56 VKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITERE 115
Query: 118 TAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEI 177
K+ N + E F + + K F L+YEE+L+R +YE
Sbjct: 116 ---KKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKYEH 172
Query: 178 VIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKG------- 230
I V+P+QL +DV+I E GI+ L+ LP + Q G
Sbjct: 173 SISVRPQQLSGRLSVDVNILESAGIASLEV----LPLHNSRQRGSGRGEDDSGPPPSTVI 228
Query: 231 -------HVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDK-ICDLLVANNHFAHFFA 282
+++F+PTV QQ + + + G F + YDV+R++ I D+ V N +F H+FA
Sbjct: 229 NQNETFANIIFKPTVVQQARI---AQNGILGDFIIRYDVNREQSIGDIQVLNGYFVHYFA 285
Query: 283 PQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKG 342
P++L + KNVVFV+D S SM G K++QTK+AL IL D++P D F ++ F R++ WK
Sbjct: 286 PKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKD 345
Query: 343 SLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLT 402
L+ + +++ + ++ S T++NG L R I +LN+ S+++ LT
Sbjct: 346 HLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLT 405
Query: 403 DGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDH 462
DG PT G T +IL N R A RG+ ++ +G G++VDF LE +S+EN G +R++E+
Sbjct: 406 DGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEE 465
Query: 463 DATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSS 522
DA QL GFY ++ PLL D+ + YP +V+ T+ Y+ GSEI++AG++ D K
Sbjct: 466 DAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDH 525
Query: 523 FKADVQAHGEGQEFSITCLVDEEEMKKLLRE---------RGHMLENHVERLWAYLTIQE 573
+V A ++F I +K ++ G NH+ERLW+YLT +E
Sbjct: 526 LHVEVTA-SNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKE 584
Query: 574 LLAKRMKVDRE-ERANLSSQALQMSLDYGFVTPLTSMSIRG-MADQDGLK 621
LL+ ++ D E E+ L +A +++ Y F+TP TSM +RG + DGL+
Sbjct: 585 LLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLE 634
>gi|194306644 BCSC-1 isoform 1 [Homo sapiens]
Length = 786
Score = 67.4 bits (163), Expect = 6e-11
Identities = 97/488 (19%), Positives = 186/488 (38%), Gaps = 84/488 (17%)
Query: 53 IRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGD 112
++S+ V+ + A T N E F + + + + F DG + +
Sbjct: 17 LKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAE 76
Query: 113 IKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHL-TVNPQSKVTFQLTYEEVLKRN 171
++DK+ A Y KA G A L+ + + F+ ++ + P SK L Y + L
Sbjct: 77 LQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLE 136
Query: 172 H---MQYEIVIKVKPKQLVHHFEIDVDIFEPQGISK---LDAQASFLPKELAAQTIKKSF 225
+++ + + P+ ++ G SK L+ + +P E T+
Sbjct: 137 ADGALRFVLPAVLNPR------------YQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVA 184
Query: 226 SGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSR------DKICDLLVANNHF-- 277
+ H + + Q +CP T L G K + VS D+ +LL+ N
Sbjct: 185 TIDSQHGIEKV----QSNCPLSPTEYL-GEDKTSAQVSLAAGHKFDRDVELLIYYNEVHT 239
Query: 278 --------------AHFFA-PQNLTNMNKNV------------VFVIDISGSMRGQ---- 306
H P + + N+ +F++D SGSM+
Sbjct: 240 PSVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQ 299
Query: 307 -----KVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRG 361
+++ KE L+ +L + G YF++ FG+ ++ V+ ++ ++ A V+
Sbjct: 300 DTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKL 359
Query: 362 FSLDEATNLNGGLLRGIEILNQVQESL--PELSNHASILIMLTDGDPTEGVTDRSQILKN 419
D L G EIL +Q P + H L + TDG+ VTD ++K
Sbjct: 360 MQAD---------LGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGE----VTDTFSVIKE 406
Query: 420 VRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPL 479
VR R + ++ G G + ++ ++ + G ++ I + + +P+
Sbjct: 407 VR-INRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPV 465
Query: 480 LVDVDLQY 487
+ DV L +
Sbjct: 466 VEDVSLSW 473
>gi|38195080 BCSC-1 isoform 1 [Homo sapiens]
Length = 786
Score = 67.4 bits (163), Expect = 6e-11
Identities = 97/488 (19%), Positives = 186/488 (38%), Gaps = 84/488 (17%)
Query: 53 IRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGD 112
++S+ V+ + A T N E F + + + + F DG + +
Sbjct: 17 LKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAE 76
Query: 113 IKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHL-TVNPQSKVTFQLTYEEVLKRN 171
++DK+ A Y KA G A L+ + + F+ ++ + P SK L Y + L
Sbjct: 77 LQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLE 136
Query: 172 H---MQYEIVIKVKPKQLVHHFEIDVDIFEPQGISK---LDAQASFLPKELAAQTIKKSF 225
+++ + + P+ ++ G SK L+ + +P E T+
Sbjct: 137 ADGALRFVLPAVLNPR------------YQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVA 184
Query: 226 SGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSR------DKICDLLVANNHF-- 277
+ H + + Q +CP T L G K + VS D+ +LL+ N
Sbjct: 185 TIDSQHGIEKV----QSNCPLSPTEYL-GEDKTSAQVSLAAGHKFDRDVELLIYYNEVHT 239
Query: 278 --------------AHFFA-PQNLTNMNKNV------------VFVIDISGSMRGQ---- 306
H P + + N+ +F++D SGSM+
Sbjct: 240 PSVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQ 299
Query: 307 -----KVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRG 361
+++ KE L+ +L + G YF++ FG+ ++ V+ ++ ++ A V+
Sbjct: 300 DTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKL 359
Query: 362 FSLDEATNLNGGLLRGIEILNQVQESL--PELSNHASILIMLTDGDPTEGVTDRSQILKN 419
D L G EIL +Q P + H L + TDG+ VTD ++K
Sbjct: 360 MQAD---------LGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGE----VTDTFSVIKE 406
Query: 420 VRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPL 479
VR R + ++ G G + ++ ++ + G ++ I + + +P+
Sbjct: 407 VR-INRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPV 465
Query: 480 LVDVDLQY 487
+ DV L +
Sbjct: 466 VEDVSLSW 473
>gi|210147462 von Willebrand factor A domain containing 5B1 [Homo
sapiens]
Length = 1215
Score = 63.2 bits (152), Expect = 1e-09
Identities = 56/229 (24%), Positives = 105/229 (45%), Gaps = 20/229 (8%)
Query: 294 VFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQ 353
+F+ID S SM G + + K+A+L L + P F+++ FG+ +S S SE +L
Sbjct: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLA 422
Query: 354 AAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESL--PELSNHASILIMLTDGDPTEGVT 411
A D ++ D + G IL+ ++ + P H +L ++TDG V
Sbjct: 423 MACDDIQRMKAD---------MGGTNILSPLKWVIRQPVHRGHPRLLFVITDG----AVN 469
Query: 412 DRSQILKNVRN-AIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQG 470
+ ++L+ VRN A R Y+ G G NV ++ ++ + G A+ + E ++
Sbjct: 470 NTGKVLELVRNHAFSTR--CYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVK 527
Query: 471 FYSQVAKPLLVDVDLQ--YPQDAVLALTQNHHKQYYEGSEIVVAGRIAD 517
+ P+L DV ++ +P+ + ++ + G +V G + D
Sbjct: 528 SLKKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYGIVCD 576
>gi|38195082 BCSC-1 isoform 2 [Homo sapiens]
Length = 415
Score = 61.6 bits (148), Expect = 3e-09
Identities = 88/422 (20%), Positives = 160/422 (37%), Gaps = 83/422 (19%)
Query: 53 IRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGD 112
++S+ V+ + A T N E F + + + + F DG + +
Sbjct: 17 LKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAE 76
Query: 113 IKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHL-TVNPQSKVTFQLTYEEVLKRN 171
++DK+ A Y KA G A L+ + + F+ ++ + P SK L Y + L
Sbjct: 77 LQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLE 136
Query: 172 H---MQYEIVIKVKPKQLVHHFEIDVDIFEPQGISK---LDAQASFLPKELAAQTIKKSF 225
+++ + + P+ ++ G SK L+ + +P E T+
Sbjct: 137 ADGALRFVLPAVLNPR------------YQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVA 184
Query: 226 SGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSR------DKICDLLVANNHF-- 277
+ H + + Q +CP T L G K + VS D+ +LL+ N
Sbjct: 185 TIDSQHGIEKV----QSNCPLSPTEYL-GEDKTSAQVSLAAGHKFDRDVELLIYYNEVHT 239
Query: 278 --------------AHFFA-PQNLTNMNKNV------------VFVIDISGSMRGQ---- 306
H P + + N+ +F++D SGSM+
Sbjct: 240 PSVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQ 299
Query: 307 -----KVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRG 361
+++ KE L+ +L + G YF++ FG+ ++ V+ ++ ++ A V+
Sbjct: 300 DTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKL 359
Query: 362 FSLDEATNLNGGLLRGIEILNQVQESL--PELSNHASILIMLTDGDPTEGVTDRSQILKN 419
D L G EIL +Q P + H L + TDG+ VTD ++K
Sbjct: 360 MQAD---------LGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGE----VTDTFSVIKE 406
Query: 420 VR 421
VR
Sbjct: 407 VR 408
>gi|54112394 calcium channel, voltage-dependent, alpha 2/delta
subunit 2 isoform b [Homo sapiens]
Length = 1143
Score = 52.4 bits (124), Expect = 2e-06
Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 11/166 (6%)
Query: 291 KNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQ--SWKGSLVQAS 348
K++V ++D+SGS+ G +K K ++ ++L + DY ++ F + Q S LVQA+
Sbjct: 290 KDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQAN 349
Query: 349 EANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTE 408
N + ++ V+G T G + Q+Q S +N +++M TDG
Sbjct: 350 VRNKKVFKEAVQGMVAKGTTGYKAGFEYAFD---QLQNSNITRANCNKMIMMFTDGG--- 403
Query: 409 GVTDRSQILKNVRNAIRGRFPLYNLGFG-HNVDFNFLEVMSMENNG 453
DR Q + N ++ G HN D L+ M+ N G
Sbjct: 404 --EDRVQDVFEKYNWPNRTVRVFTFSVGQHNYDVTPLQWMACANKG 447
>gi|54112392 calcium channel, voltage-dependent, alpha 2/delta
subunit 2 isoform a [Homo sapiens]
Length = 1145
Score = 52.4 bits (124), Expect = 2e-06
Identities = 44/166 (26%), Positives = 75/166 (45%), Gaps = 11/166 (6%)
Query: 291 KNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQ--SWKGSLVQAS 348
K++V ++D+SGS+ G +K K ++ ++L + DY ++ F + Q S LVQA+
Sbjct: 290 KDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQAN 349
Query: 349 EANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTE 408
N + ++ V+G T G + Q+Q S +N +++M TDG
Sbjct: 350 VRNKKVFKEAVQGMVAKGTTGYKAGFEYAFD---QLQNSNITRANCNKMIMMFTDGG--- 403
Query: 409 GVTDRSQILKNVRNAIRGRFPLYNLGFG-HNVDFNFLEVMSMENNG 453
DR Q + N ++ G HN D L+ M+ N G
Sbjct: 404 --EDRVQDVFEKYNWPNRTVRVFTFSVGQHNYDVTPLQWMACANKG 447
>gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subunit
[Homo sapiens]
Length = 1137
Score = 50.4 bits (119), Expect = 7e-06
Identities = 43/200 (21%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Query: 291 KNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQ----SWKGSLVQ 346
K++V ++D+SGSM+G ++ K + IL + D+ +++ + V +KG LVQ
Sbjct: 290 KDIVILVDVSGSMKGLRMTIAKHTITTILDTLGENDFINIIAYNDYVHYIEPCFKGILVQ 349
Query: 347 ASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLP-ELSNHASILIMLTDGD 405
A N + + V + ++ L +IL Q QE+ L N A +LI
Sbjct: 350 ADRDNREHFKLLVEELMVKGVGVVDQALREAFQILKQFQEAKQGSLCNQAIMLI------ 403
Query: 406 PTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDF-NFLEVMSMENNGRAQRIYEDHDA 464
++G + + + N + ++ G V F + ++ ++ N G +I D
Sbjct: 404 -SDGAVEDYEPVFEKYNWPDCKVRVFTYLIGREVSFADRMKWIACNNKGYYTQISTLADT 462
Query: 465 TQQLQGFYSQVAKPLLVDVD 484
+ + + +++P++++ D
Sbjct: 463 QENVMEYLHVLSRPMVINHD 482
>gi|54112390 calcium channel, voltage-dependent, alpha 2/delta
subunit 1 [Homo sapiens]
Length = 1091
Score = 46.6 bits (109), Expect = 1e-04
Identities = 45/197 (22%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 291 KNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQ--SWKGSLVQAS 348
K+++ ++D+SGS+ G +K + ++ ++L + D+ ++ F + Q S LVQA+
Sbjct: 252 KDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQAN 311
Query: 349 EANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDGDPTE 408
N + +D V + T+ G E L S +N I+++ TDG
Sbjct: 312 VRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVS---RANCNKIIMLFTDGG--- 365
Query: 409 GVTDRSQILKNVRNAIRGRFPLYNLGFG-HNVDFNFLEVMSMENNGRAQRIYEDHDATQQ 467
+R+Q + N N + + ++ G HN D ++ M+ EN G I
Sbjct: 366 --EERAQEIFNKYNKDK-KVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRIN 422
Query: 468 LQGFYSQVAKPLLVDVD 484
Q + + +P+++ D
Sbjct: 423 TQEYLDVLGRPMVLAGD 439
>gi|118918435 von Willebrand factor A domain containing 3B [Homo
sapiens]
Length = 1294
Score = 45.1 bits (105), Expect = 3e-04
Identities = 35/153 (22%), Positives = 72/153 (47%), Gaps = 25/153 (16%)
Query: 290 NKNVVFVIDISGSMRGQKVKQTKEALLKILGD-MQPGDYFDLVLFGTRVQSWKGSLVQAS 348
N + +ID S SM+ K+ K+ +++ + + ++ F+ V F + +W+ L + +
Sbjct: 506 NDCIYILIDTSHSMKS-KLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVN 564
Query: 349 EANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDG---D 405
E NL+ AQ ++R + +TN L+ ++ + + A + +LTDG
Sbjct: 565 EDNLEQAQSWIRDIKIGSSTN----------TLSALKTAFADKETQA--IYLLTDGRPDQ 612
Query: 406 PTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHN 438
P E V D+ + + + P+Y + F +N
Sbjct: 613 PPETVIDQVKRFQEI--------PIYTISFNYN 637
>gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
subunit [Homo sapiens]
Length = 1091
Score = 43.9 bits (102), Expect = 7e-04
Identities = 45/203 (22%), Positives = 87/203 (42%), Gaps = 23/203 (11%)
Query: 291 KNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQ----SWKGSLVQ 346
K+VV ++D+SGSM+G ++ K+ + IL + D+F+++ + + G+LVQ
Sbjct: 255 KDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQ 314
Query: 347 ASEANLQAAQD-----FVRGFS-LDEATNLNGGLLRGIEILNQVQESLPELSNHASILIM 400
A N + ++ F +G LD A N +L Q + + A +LI
Sbjct: 315 ADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQ-----GSICSQAIMLI- 368
Query: 401 LTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDF-NFLEVMSMENNGRAQRIY 459
T+G D + N + ++ G F + L+ M+ N G +I
Sbjct: 369 ------TDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQIS 422
Query: 460 EDHDATQQLQGFYSQVAKPLLVD 482
D + + + +++P ++D
Sbjct: 423 TLADVQENVMEYLHVLSRPKVID 445
>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
sapiens]
Length = 1724
Score = 43.5 bits (101), Expect = 9e-04
Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 3/132 (2%)
Query: 34 RSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPK 93
++ SS K D + + V + + + ++ A +V N ++ E + +
Sbjct: 604 KTSSSTKAGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDD 663
Query: 94 TAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHL-TV 152
A + F +G +G+IK+K A ++Y +A G A L+ S + FT+ + +
Sbjct: 664 KAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLM--SQDAPDVFTVSVGNL 721
Query: 153 NPQSKVTFQLTY 164
P++KV ++TY
Sbjct: 722 PPKAKVLIKITY 733
>gi|218505703 von Willebrand factor A domain containing 3A [Homo
sapiens]
Length = 1184
Score = 42.7 bits (99), Expect = 0.002
Identities = 38/137 (27%), Positives = 64/137 (46%), Gaps = 18/137 (13%)
Query: 287 TNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDM--QPGDYFDLVLFGTRVQSWKGSL 344
T + V ++D SGSM G ++Q K L+ ++ + + D F+L+ F QSW+ +L
Sbjct: 954 TVLESKVCILLDTSGSM-GPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTL 1012
Query: 345 VQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDG 404
V+ ++A A +V +T++ LL+ S +L L +LTDG
Sbjct: 1013 VETTDAACHEAMQWVTHLQAQGSTSILQALLKAF--------SFHDLEG----LYLLTDG 1060
Query: 405 DPTEGVTDRSQILKNVR 421
P T S +L V+
Sbjct: 1061 KPD---TSCSLVLNEVQ 1074
Score = 41.6 bits (96), Expect = 0.003
Identities = 24/94 (25%), Positives = 44/94 (46%)
Query: 287 TNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQ 346
T K VV ++DIS + + L + + D F+L+ FG+ ++SW+ +V
Sbjct: 506 TVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVP 565
Query: 347 ASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEI 380
S NLQ+A + + N+ L + +E+
Sbjct: 566 VSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEV 599
Score = 32.0 bits (71), Expect = 2.7
Identities = 38/173 (21%), Positives = 77/173 (44%), Gaps = 18/173 (10%)
Query: 293 VVFVIDISGSMRGQKVKQTKEALLKILGD-MQPGDYFDLVLFGTRVQSWKGSLVQASEAN 351
V +ID+S G + ++ ++ L+ ++ + + + ++ FGT S ++ S +
Sbjct: 171 VSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSAST 230
Query: 352 LQAAQDFVRGFSLDEATNLNGGL-----LRGIEILNQVQESLPE-----LSNHASILIML 401
LQ + +V+ D +NL L L+G++ L + S P+ LS++ M
Sbjct: 231 LQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQSTMG 290
Query: 402 TDGDPTEGVTDRSQ------ILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMS 448
D +T R +LKN+ A+RG + Y+ H + E+++
Sbjct: 291 RDLI-IHFITYRCDDQMPPAVLKNLAEAVRGYYHCYSPKMEHYTSRDMDELLA 342
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 34.3 bits (77), Expect = 0.54
Identities = 43/186 (23%), Positives = 82/186 (44%), Gaps = 34/186 (18%)
Query: 288 NMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQA 347
N ++VF+ID S S+ + KE ++ IL + D+ TRV +
Sbjct: 53 NKRADLVFIIDSSRSVNTHDYAKVKEFIVDIL------QFLDIGPDVTRVGLLQYGSTVK 106
Query: 348 SEANLQAAQDFVRGFSLDEAT----NLNGGLLRGIEI-------LNQVQESLPELSNHAS 396
+E +L+ F R ++ A +L+ G + G+ I ++ + + P N
Sbjct: 107 NEFSLKT---FKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPR 163
Query: 397 ILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQ 456
+++++TDG P + V +++ R+ ++ +G G VDFN L+ + E
Sbjct: 164 VIMIVTDGRPQDSV---AEVAAKARDT---GILIFAIGVG-QVDFNTLKSIGSEP----- 211
Query: 457 RIYEDH 462
+EDH
Sbjct: 212 --HEDH 215
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 34.3 bits (77), Expect = 0.54
Identities = 43/186 (23%), Positives = 82/186 (44%), Gaps = 34/186 (18%)
Query: 288 NMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQA 347
N ++VF+ID S S+ + KE ++ IL + D+ TRV +
Sbjct: 53 NKRADLVFIIDSSRSVNTHDYAKVKEFIVDIL------QFLDIGPDVTRVGLLQYGSTVK 106
Query: 348 SEANLQAAQDFVRGFSLDEAT----NLNGGLLRGIEI-------LNQVQESLPELSNHAS 396
+E +L+ F R ++ A +L+ G + G+ I ++ + + P N
Sbjct: 107 NEFSLKT---FKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPR 163
Query: 397 ILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQ 456
+++++TDG P + V +++ R+ ++ +G G VDFN L+ + E
Sbjct: 164 VIMIVTDGRPQDSV---AEVAAKARDT---GILIFAIGVG-QVDFNTLKSIGSEP----- 211
Query: 457 RIYEDH 462
+EDH
Sbjct: 212 --HEDH 215
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 34.3 bits (77), Expect = 0.54
Identities = 23/89 (25%), Positives = 39/89 (43%)
Query: 512 AGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTI 571
A ++ K + F+ V+ H + +T E EM++ LR LE H E L +
Sbjct: 215 AQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQV 274
Query: 572 QELLAKRMKVDREERANLSSQALQMSLDY 600
+LL + + + LS Q QM ++
Sbjct: 275 VDLLQQELTAAEQRNQILSQQLQQMEAEH 303
>gi|13654239 WW domain containing E3 ubiquitin protein ligase 1
[Homo sapiens]
Length = 922
Score = 31.6 bits (70), Expect = 3.5
Identities = 18/73 (24%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 123 YRKAAISGENAGLVRASGRTMEQFTIHLTVN--PQSKVTFQLTYEEVLKRNHMQYEIVIK 180
Y + + GE ++S + ++ LTVN PQ+ + FQ+ LK + + + I
Sbjct: 41 YTEVVVDGEITKTAKSSSSSNPKWDEQLTVNVTPQTTLEFQVWSHRTLKADALLGKATID 100
Query: 181 VKPKQLVHHFEID 193
+K L+H+ +++
Sbjct: 101 LKQALLIHNRKLE 113
>gi|211971038 tousled-like kinase 1 isoform 3 [Homo sapiens]
Length = 670
Score = 31.6 bits (70), Expect = 3.5
Identities = 33/146 (22%), Positives = 68/146 (46%), Gaps = 14/146 (9%)
Query: 546 EMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQ--ALQMSLDYGFV 603
++++ + E+ +LE + ERL ++ ++K++ +++ + LSS+ ++Q L G
Sbjct: 152 DLRRQIDEQQKLLEKYKERLNKCIS----MSKKLLIEKSTQEKLSSREKSMQDRLRLGHF 207
Query: 604 TPL------TSMSIRGMADQDGLKPT--IDKPSEDSPPLEMLGPRRTFVLSALQPSPTHS 655
T + T G A Q+ +K +++ ED L +R + +P+ +
Sbjct: 208 TTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTN 267
Query: 656 SSNTQRLPDRVTGVDTDPHFIIHVPQ 681
S QR V G + DP ++PQ
Sbjct: 268 SEPKQRKNKAVNGAENDPFVRPNLPQ 293
>gi|211971036 tousled-like kinase 1 isoform 2 [Homo sapiens]
Length = 718
Score = 31.6 bits (70), Expect = 3.5
Identities = 33/146 (22%), Positives = 68/146 (46%), Gaps = 14/146 (9%)
Query: 546 EMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQ--ALQMSLDYGFV 603
++++ + E+ +LE + ERL ++ ++K++ +++ + LSS+ ++Q L G
Sbjct: 200 DLRRQIDEQQKLLEKYKERLNKCIS----MSKKLLIEKSTQEKLSSREKSMQDRLRLGHF 255
Query: 604 TPL------TSMSIRGMADQDGLKPT--IDKPSEDSPPLEMLGPRRTFVLSALQPSPTHS 655
T + T G A Q+ +K +++ ED L +R + +P+ +
Sbjct: 256 TTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTN 315
Query: 656 SSNTQRLPDRVTGVDTDPHFIIHVPQ 681
S QR V G + DP ++PQ
Sbjct: 316 SEPKQRKNKAVNGAENDPFVRPNLPQ 341
>gi|33636698 tousled-like kinase 1 isoform 1 [Homo sapiens]
Length = 766
Score = 31.6 bits (70), Expect = 3.5
Identities = 33/146 (22%), Positives = 68/146 (46%), Gaps = 14/146 (9%)
Query: 546 EMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQ--ALQMSLDYGFV 603
++++ + E+ +LE + ERL ++ ++K++ +++ + LSS+ ++Q L G
Sbjct: 248 DLRRQIDEQQKLLEKYKERLNKCIS----MSKKLLIEKSTQEKLSSREKSMQDRLRLGHF 303
Query: 604 TPL------TSMSIRGMADQDGLKPT--IDKPSEDSPPLEMLGPRRTFVLSALQPSPTHS 655
T + T G A Q+ +K +++ ED L +R + +P+ +
Sbjct: 304 TTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTN 363
Query: 656 SSNTQRLPDRVTGVDTDPHFIIHVPQ 681
S QR V G + DP ++PQ
Sbjct: 364 SEPKQRKNKAVNGAENDPFVRPNLPQ 389
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 31.2 bits (69), Expect = 4.6
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 20/132 (15%)
Query: 292 NVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEAN 351
++VF+ID S S+R + + K + +I+ D D+ TRV + E
Sbjct: 83 DLVFIIDSSRSVRPLEFTKVKTFVSRII------DTLDIGPADTRVAVVNYASTVKIEFQ 136
Query: 352 LQAAQDFVRGFSLDEA----TNLNGGLLRGIEILNQVQESL-------PELSNHASILIM 400
LQA D SL +A T L+ G + G+ I + E+ SN + I+
Sbjct: 137 LQAYTD---KQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAII 193
Query: 401 LTDGDPTEGVTD 412
+TDG P + V +
Sbjct: 194 VTDGRPQDQVNE 205
>gi|190684671 mitogen-activated protein kinase binding protein 1
isoform a [Homo sapiens]
Length = 1508
Score = 30.8 bits (68), Expect = 6.0
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 6/96 (6%)
Query: 602 FVTPLTSMSIRGMADQ---DGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSN 658
+V P +S+R M D + L P++ PS+DS + GPR+ AL+ S T S N
Sbjct: 851 WVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPRK-HGQEALETSLT--SQN 907
Query: 659 TQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEP 694
+ + + + PH I + Q+E ++ P
Sbjct: 908 EKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAP 943
>gi|190684677 mitogen-activated protein kinase binding protein 1
isoform b [Homo sapiens]
Length = 1514
Score = 30.8 bits (68), Expect = 6.0
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 6/96 (6%)
Query: 602 FVTPLTSMSIRGMADQ---DGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSN 658
+V P +S+R M D + L P++ PS+DS + GPR+ AL+ S T S N
Sbjct: 857 WVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPRK-HGQEALETSLT--SQN 913
Query: 659 TQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEP 694
+ + + + PH I + Q+E ++ P
Sbjct: 914 EKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAP 949
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,037,342
Number of Sequences: 37866
Number of extensions: 1449627
Number of successful extensions: 3460
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3383
Number of HSP's gapped (non-prelim): 43
length of query: 911
length of database: 18,247,518
effective HSP length: 111
effective length of query: 800
effective length of database: 14,044,392
effective search space: 11235513600
effective search space used: 11235513600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.