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Search of human proteins with 156104878
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156104878 glutaminase [Homo sapiens]
(669 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156104878 glutaminase [Homo sapiens] 1368 0.0
gi|20336214 glutaminase 2 [Homo sapiens] 828 0.0
gi|118150656 ankyrin repeat domain 7 [Homo sapiens] 57 7e-08
gi|38569428 ankyrin repeat domain protein 5 [Homo sapiens] 52 2e-06
gi|38569426 ankyrin repeat domain protein 5 [Homo sapiens] 52 2e-06
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 50 7e-06
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 49 1e-05
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 49 1e-05
gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens] 49 1e-05
gi|58331117 ankyrin repeat domain 16 isoform c [Homo sapiens] 48 3e-05
gi|58331113 ankyrin repeat domain 16 isoform a [Homo sapiens] 48 3e-05
gi|58331111 ankyrin repeat domain 16 isoform a [Homo sapiens] 48 3e-05
gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 1... 48 3e-05
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 48 3e-05
gi|140161500 ankyrin repeat and sterile alpha motif domain conta... 48 3e-05
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 48 3e-05
gi|39812133 ankyrin repeat domain 2 isoform a [Homo sapiens] 47 4e-05
gi|194018403 ankyrin repeat domain 2 isoform b [Homo sapiens] 47 4e-05
gi|24041035 notch 2 preproprotein [Homo sapiens] 46 1e-04
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 46 1e-04
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 46 1e-04
gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo ... 46 1e-04
gi|28605137 proteasome 26S non-ATPase subunit 10 isform 2 [Homo ... 46 1e-04
gi|34304381 inversin isoform a [Homo sapiens] 46 1e-04
gi|34304379 inversin isoform b [Homo sapiens] 46 1e-04
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 45 2e-04
gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 45 2e-04
gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Hom... 45 3e-04
gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Hom... 45 3e-04
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 45 3e-04
>gi|156104878 glutaminase [Homo sapiens]
Length = 669
Score = 1368 bits (3542), Expect = 0.0
Identities = 669/669 (100%), Positives = 669/669 (100%)
Query: 1 MMRLRGSGMLRDLLLRSPAGVSATLRRAQPLVTLCRRPRGGGRPAAGPAAAARLHPWWGG 60
MMRLRGSGMLRDLLLRSPAGVSATLRRAQPLVTLCRRPRGGGRPAAGPAAAARLHPWWGG
Sbjct: 1 MMRLRGSGMLRDLLLRSPAGVSATLRRAQPLVTLCRRPRGGGRPAAGPAAAARLHPWWGG 60
Query: 61 GGWPAEPLARGLSSSPSEILQELGKGSTHPQPGVSPPAAPAAPGPKDGPGETDAFGNSEG 120
GGWPAEPLARGLSSSPSEILQELGKGSTHPQPGVSPPAAPAAPGPKDGPGETDAFGNSEG
Sbjct: 61 GGWPAEPLARGLSSSPSEILQELGKGSTHPQPGVSPPAAPAAPGPKDGPGETDAFGNSEG 120
Query: 121 KELVASGENKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMD 180
KELVASGENKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMD
Sbjct: 121 KELVASGENKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMD 180
Query: 181 MLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKK 240
MLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKK
Sbjct: 181 MLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKK 240
Query: 241 QSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDL 300
QSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDL
Sbjct: 241 QSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDL 300
Query: 301 GTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQ 360
GTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQ
Sbjct: 301 GTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQ 360
Query: 361 FLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSI 420
FLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSI
Sbjct: 361 FLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSI 420
Query: 421 EVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPA 480
EVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPA
Sbjct: 421 EVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPA 480
Query: 481 KSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKL 540
KSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKL
Sbjct: 481 KSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKL 540
Query: 541 DPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVE 600
DPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVE
Sbjct: 541 DPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVE 600
Query: 601 VVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQT 660
VVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQT
Sbjct: 601 VVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQT 660
Query: 661 VHKNLDGLL 669
VHKNLDGLL
Sbjct: 661 VHKNLDGLL 669
>gi|20336214 glutaminase 2 [Homo sapiens]
Length = 602
Score = 828 bits (2139), Expect = 0.0
Identities = 395/538 (73%), Positives = 458/538 (85%)
Query: 132 KQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSD 191
+ G+L L DLLFYTIAEGQE+IP+HKF TALK+TGL+TSDPRL++CM + +Q +S
Sbjct: 65 ESGMLSRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLRDCMSEMHRVVQESSS 124
Query: 192 GVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIP 251
G +LD+DLF+KCV SNIVLLTQAFR+KFVIPDF FT H+D ++E K+ +GGKVA YIP
Sbjct: 125 GGLLDRDLFRKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDVKELTGGKVAAYIP 184
Query: 252 QLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGK 311
QLAK +PDLWGVS+CTVDGQRHS G TK+PFCLQSCVKPL YAI+++ LGT+YVH++VGK
Sbjct: 185 QLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISISTLGTDYVHKFVGK 244
Query: 312 EPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYV 371
EPSGLR+NKL LNE+ PHNPMVNAGAIVV+SLIK N AEKFD+V+Q+LNKMAGNEY+
Sbjct: 245 EPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAGNEYM 304
Query: 372 GFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMA 431
GFSNATFQSE+E+GDRN+AIGYYLKEKKCFP+G DM+ LD YFQLCS+EVTCES SVMA
Sbjct: 305 GFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESGSVMA 364
Query: 432 ATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLV 491
ATLANGG CPITGE VLS EAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKS V+G ILLV
Sbjct: 365 ATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGAILLV 424
Query: 492 VPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRV 551
VPNVMGMMC SPPLDK+GNS +G FC LVSL NFHNYDNLRH A+KLDPRREG + R
Sbjct: 425 VPNVMGMMCLSPPLDKLGNSHRGTSFCQKLVSLFNFHNYDNLRHCARKLDPRREGAEIRN 484
Query: 552 KSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKV 611
K+V+NLLFAAY+GDVSALRRFALSAMDMEQ+DYDSRTALHVAAAEGH+EVVKFL+EACKV
Sbjct: 485 KTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKV 544
Query: 612 NPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQTVHKNLDGLL 669
NPF KDRW N P+D+A+ F H +V K+LQ+YQ YT +NL+ ++
Sbjct: 545 NPFAKDRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTLSETQAEAAAEALSKENLESMV 602
>gi|118150656 ankyrin repeat domain 7 [Homo sapiens]
Length = 254
Score = 56.6 bits (135), Expect = 7e-08
Identities = 36/107 (33%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
Query: 538 KKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFA-LSAMDMEQRDYDSRTALHVAAAE 596
+K + R +G + R K + L AA GD+ L+ + + D+ +D RT LH+A A
Sbjct: 10 RKNETRSQGYNLREKDLKKLHRAASVGDLKKLKEYLQIKKYDVNMQDKKYRTPLHLACAN 69
Query: 597 GHVEVVKFLLE-ACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEY 642
GH +VV FL+E CK+N +D N +P+ +A+ + D IL +
Sbjct: 70 GHTDVVLFLIEQQCKIN--VRDSENKSPLIKAVQCQNEDCATILLNF 114
Score = 30.8 bits (68), Expect = 4.2
Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 590 LHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQ 649
LH AA+ G ++ +K L+ K + +D+ TP+ A GH DV L E Q + +
Sbjct: 29 LHRAASVGDLKKLKEYLQIKKYDVNMQDKKYRTPLHLACANGHTDVVLFLIEQQCKINVR 88
Query: 650 GDSDN 654
DS+N
Sbjct: 89 -DSEN 92
Score = 29.6 bits (65), Expect = 9.4
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 5/115 (4%)
Query: 548 DQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE 607
D R +V++ +A +S + + D+E ++ D T L VA + ++VKFLLE
Sbjct: 122 DIRYNTVLH--YAVCGQSLSLVEKLLEYEADLEAKNKDGYTPLLVAVINNNPKMVKFLLE 179
Query: 608 -ACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQTV 661
VN D + T + A+ + K+L + V+ +G D+ N +
Sbjct: 180 KGADVN--ASDNYQRTALILAVSGEPPCLVKLLLQQGVELCYEGIVDSQLRNMFI 232
>gi|38569428 ankyrin repeat domain protein 5 [Homo sapiens]
Length = 776
Score = 51.6 bits (122), Expect = 2e-06
Identities = 33/94 (35%), Positives = 54/94 (57%), Gaps = 5/94 (5%)
Query: 549 QRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE- 607
++V S IN++ A GD+++L++ S + ++ +D +T L A A G+++VVKFLLE
Sbjct: 490 EKVFSNINIITKA--GDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEK 547
Query: 608 ACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
VN W TP+ A H G D+ ++L E
Sbjct: 548 GANVNATDNFLW--TPLHFACHAGQQDIVELLVE 579
Score = 33.5 bits (75), Expect = 0.65
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Query: 588 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYT 647
+ALH+A+ +++V FLL+ +P +DR TP A GH +IL + + T
Sbjct: 50 SALHLASVSNDIDMVSFLLD-LGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMT 108
Score = 33.1 bits (74), Expect = 0.85
Identities = 25/61 (40%), Positives = 32/61 (52%), Gaps = 11/61 (18%)
Query: 587 RTALHVAAAEGHVEVVKFLLE-ACKVNPFPKDRWNNTPMDEALHF----GHHDVFKILQE 641
RTAL A+ EG VE+V+ +LE +VN F DR A HF G D+ K+L
Sbjct: 186 RTALMEASREGVVEIVRGILERGGEVNAFDNDR------HHAAHFAAKGGFFDILKLLFA 239
Query: 642 Y 642
Y
Sbjct: 240 Y 240
>gi|38569426 ankyrin repeat domain protein 5 [Homo sapiens]
Length = 776
Score = 51.6 bits (122), Expect = 2e-06
Identities = 33/94 (35%), Positives = 54/94 (57%), Gaps = 5/94 (5%)
Query: 549 QRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE- 607
++V S IN++ A GD+++L++ S + ++ +D +T L A A G+++VVKFLLE
Sbjct: 490 EKVFSNINIITKA--GDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEK 547
Query: 608 ACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
VN W TP+ A H G D+ ++L E
Sbjct: 548 GANVNATDNFLW--TPLHFACHAGQQDIVELLVE 579
Score = 33.5 bits (75), Expect = 0.65
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Query: 588 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYT 647
+ALH+A+ +++V FLL+ +P +DR TP A GH +IL + + T
Sbjct: 50 SALHLASVSNDIDMVSFLLD-LGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMT 108
Score = 33.1 bits (74), Expect = 0.85
Identities = 25/61 (40%), Positives = 32/61 (52%), Gaps = 11/61 (18%)
Query: 587 RTALHVAAAEGHVEVVKFLLE-ACKVNPFPKDRWNNTPMDEALHF----GHHDVFKILQE 641
RTAL A+ EG VE+V+ +LE +VN F DR A HF G D+ K+L
Sbjct: 186 RTALMEASREGVVEIVRGILERGGEVNAFDNDR------HHAAHFAAKGGFFDILKLLFA 239
Query: 642 Y 642
Y
Sbjct: 240 Y 240
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 50.1 bits (118), Expect = 7e-06
Identities = 34/105 (32%), Positives = 53/105 (50%), Gaps = 9/105 (8%)
Query: 539 KLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGH 598
K++ R E G+ R+ AA GD ++ D+ +D+ TALH A G+
Sbjct: 160 KVNKRNERGETRLHR------AAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGY 213
Query: 599 VEVVKFLLEA-CKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEY 642
+V K LL A +VN D ++TP+ +A + GH+ V K+L Y
Sbjct: 214 YDVAKQLLAAGAEVNTKGLD--DDTPLHDAANNGHYKVVKLLLRY 256
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 49.3 bits (116), Expect = 1e-05
Identities = 31/85 (36%), Positives = 48/85 (56%), Gaps = 4/85 (4%)
Query: 560 AAYTGDVSALRR-FALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLL-EACKVNPFPKD 617
AA GD + + R A + D++ D RTALH+A A GHV+VV L+ C+++ + K+
Sbjct: 40 AAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKE 99
Query: 618 RWNNTPMDEALHFGHHDVFKILQEY 642
N TP+ +A+H IL E+
Sbjct: 100 --NRTPLIQAVHCQEEACAVILLEH 122
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 49.3 bits (116), Expect = 1e-05
Identities = 31/85 (36%), Positives = 48/85 (56%), Gaps = 4/85 (4%)
Query: 560 AAYTGDVSALRR-FALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLL-EACKVNPFPKD 617
AA GD + + R A + D++ D RTALH+A A GHV+VV L+ C+++ + K+
Sbjct: 40 AAVKGDAAEMERCLARRSGDLDALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKE 99
Query: 618 RWNNTPMDEALHFGHHDVFKILQEY 642
N TP+ +A+H IL E+
Sbjct: 100 --NRTPLIQAVHCQEEACAVILLEH 122
>gi|116063534 ankyrin repeat domain 27 (VPS9 domain) [Homo sapiens]
Length = 1050
Score = 48.9 bits (115), Expect = 1e-05
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
Query: 582 RDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
R+ D LH+A +GH +VVK LL++ P KD NTP+ A GHH++ +L
Sbjct: 773 RNADQAVPLHLACQQGHFQVVKCLLDS-NAKPNKKDLSGNTPLIYACSGGHHELVALL-- 829
Query: 642 YQVQYTPQGDSDNGKENQTVHK 663
+Q+ ++ N K N +H+
Sbjct: 830 --LQHGASINASNNKGNTALHE 849
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 2/103 (1%)
Query: 560 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 619
AA G S + + DY T LH+A +G+ V LL K + +D
Sbjct: 470 AAVCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLLLHY-KASAEVQDNN 528
Query: 620 NNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKENQTVH 662
NTP+ A +GH D K L Y V+ + + D N K + +H
Sbjct: 529 GNTPLHLACTYGHEDCVKALVYYDVE-SCRLDIGNEKGDTPLH 570
>gi|58331117 ankyrin repeat domain 16 isoform c [Homo sapiens]
Length = 304
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/53 (43%), Positives = 32/53 (60%)
Query: 587 RTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 639
RT LH AA GH+E VK LL+ C+ P +D T + +A+ GH DV ++L
Sbjct: 172 RTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCGHIDVARLL 224
Score = 35.8 bits (81), Expect = 0.13
Identities = 19/52 (36%), Positives = 27/52 (51%)
Query: 588 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 639
T LH AA GH +V+ +L EA ++ +R P+ EA GH D + L
Sbjct: 39 TLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYL 90
Score = 33.9 bits (76), Expect = 0.50
Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Query: 582 RDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
++ D + H+A+ EG ++++LL C + + TP+ A GH + K+L +
Sbjct: 133 KNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLK 192
Query: 642 YQVQYTP 648
+ QY P
Sbjct: 193 -RCQYEP 198
Score = 29.6 bits (65), Expect = 9.4
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 577 MDMEQRDYDSRTALHVAAAEGHVEVVKFLL-EACKVNPFPKDRWNNTPM 624
MD+E + D + LH AA+ GH + V++LL V+ K W TP+
Sbjct: 62 MDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAAVDCLKKADW--TPL 108
>gi|58331113 ankyrin repeat domain 16 isoform a [Homo sapiens]
Length = 361
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/53 (43%), Positives = 32/53 (60%)
Query: 587 RTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 639
RT LH AA GH+E VK LL+ C+ P +D T + +A+ GH DV ++L
Sbjct: 172 RTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCGHIDVARLL 224
Score = 36.6 bits (83), Expect = 0.077
Identities = 18/52 (34%), Positives = 29/52 (55%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA 608
L +AA G S ++ D+ +D +R+ALH+A A H+ KFLL++
Sbjct: 278 LHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLLQS 329
Score = 35.8 bits (81), Expect = 0.13
Identities = 19/52 (36%), Positives = 27/52 (51%)
Query: 588 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 639
T LH AA GH +V+ +L EA ++ +R P+ EA GH D + L
Sbjct: 39 TLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYL 90
Score = 33.9 bits (76), Expect = 0.50
Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Query: 582 RDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
++ D + H+A+ EG ++++LL C + + TP+ A GH + K+L +
Sbjct: 133 KNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLK 192
Query: 642 YQVQYTP 648
+ QY P
Sbjct: 193 -RCQYEP 198
Score = 29.6 bits (65), Expect = 9.4
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 577 MDMEQRDYDSRTALHVAAAEGHVEVVKFLL-EACKVNPFPKDRWNNTPM 624
MD+E + D + LH AA+ GH + V++LL V+ K W TP+
Sbjct: 62 MDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAAVDCLKKADW--TPL 108
Score = 29.6 bits (65), Expect = 9.4
Identities = 21/50 (42%), Positives = 29/50 (58%), Gaps = 4/50 (8%)
Query: 560 AAYTGDVSALRRFALSAM--DMEQRDYDSR-TALHVAAAEGHVEVVKFLL 606
AA TG A+R F +S + D++ R + TALH AA EGH ++ LL
Sbjct: 246 AAVTGQDEAIR-FLVSELGVDVDVRATSTHLTALHYAAKEGHTSTIQTLL 294
>gi|58331111 ankyrin repeat domain 16 isoform a [Homo sapiens]
Length = 361
Score = 48.1 bits (113), Expect = 3e-05
Identities = 23/53 (43%), Positives = 32/53 (60%)
Query: 587 RTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 639
RT LH AA GH+E VK LL+ C+ P +D T + +A+ GH DV ++L
Sbjct: 172 RTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAIQCGHIDVARLL 224
Score = 36.6 bits (83), Expect = 0.077
Identities = 18/52 (34%), Positives = 29/52 (55%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA 608
L +AA G S ++ D+ +D +R+ALH+A A H+ KFLL++
Sbjct: 278 LHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLLQS 329
Score = 35.8 bits (81), Expect = 0.13
Identities = 19/52 (36%), Positives = 27/52 (51%)
Query: 588 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 639
T LH AA GH +V+ +L EA ++ +R P+ EA GH D + L
Sbjct: 39 TLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYL 90
Score = 33.9 bits (76), Expect = 0.50
Identities = 18/67 (26%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Query: 582 RDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
++ D + H+A+ EG ++++LL C + + TP+ A GH + K+L +
Sbjct: 133 KNKDGWNSFHIASREGDPLILQYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLK 192
Query: 642 YQVQYTP 648
+ QY P
Sbjct: 193 -RCQYEP 198
Score = 29.6 bits (65), Expect = 9.4
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 577 MDMEQRDYDSRTALHVAAAEGHVEVVKFLL-EACKVNPFPKDRWNNTPM 624
MD+E + D + LH AA+ GH + V++LL V+ K W TP+
Sbjct: 62 MDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGAAVDCLKKADW--TPL 108
Score = 29.6 bits (65), Expect = 9.4
Identities = 21/50 (42%), Positives = 29/50 (58%), Gaps = 4/50 (8%)
Query: 560 AAYTGDVSALRRFALSAM--DMEQRDYDSR-TALHVAAAEGHVEVVKFLL 606
AA TG A+R F +S + D++ R + TALH AA EGH ++ LL
Sbjct: 246 AAVTGQDEAIR-FLVSELGVDVDVRATSTHLTALHYAAKEGHTSTIQTLL 294
>gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 16B
[Homo sapiens]
Length = 567
Score = 48.1 bits (113), Expect = 3e-05
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 532 NLRHFAKKLDPRREGGDQRVK----SVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSR 587
+L+H +K + +R G +R K + + LL A+ D +R F + + + + D
Sbjct: 43 DLQHRKRKHERKRSTGGRRKKVSFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGL 102
Query: 588 TALHVAAAEGHVEVVKFLL-EACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEY 642
TALH + E+VK LL VN + W TP+ A GH ++ KIL +Y
Sbjct: 103 TALHQCCIDNFEEIVKLLLSHGANVNAKDNELW--TPLHAAATCGHINLVKILVQY 156
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 47.8 bits (112), Expect = 3e-05
Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 4/85 (4%)
Query: 560 AAYTGDVSALRR-FALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLL-EACKVNPFPKD 617
AA GD + + R A + D++ D RTALH+A A GHV+VV L+ C+++ K+
Sbjct: 40 AAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKE 99
Query: 618 RWNNTPMDEALHFGHHDVFKILQEY 642
N TP+ +A+H IL E+
Sbjct: 100 --NRTPLIQAVHCQEEACAVILLEH 122
>gi|140161500 ankyrin repeat and sterile alpha motif domain
containing 1 [Homo sapiens]
Length = 1134
Score = 47.8 bits (112), Expect = 3e-05
Identities = 33/91 (36%), Positives = 47/91 (51%), Gaps = 4/91 (4%)
Query: 552 KSVINLLFAAYTGDVSALRRF---ALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA 608
K L AA+ GD +R S + +++ D+ TALH AA GH EVVK LLE
Sbjct: 112 KGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEE 171
Query: 609 CKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 639
+P ++ TP+D A +G +V K+L
Sbjct: 172 L-TDPTMRNNKFETPLDLAALYGRLEVVKML 201
Score = 32.3 bits (72), Expect = 1.5
Identities = 24/56 (42%), Positives = 28/56 (50%), Gaps = 10/56 (17%)
Query: 588 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALH----FGHHDVFKIL 639
T LH+AA GH VV+ LL+A D T M ALH FG DV +IL
Sbjct: 217 TPLHLAARNGHKAVVQVLLDA------GMDSNYQTEMGSALHEAALFGKTDVVQIL 266
Score = 30.8 bits (68), Expect = 4.2
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 6/56 (10%)
Query: 590 LHVAAAEGHVEVVKFLLEA----CKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
LH+AA +G ++V+ L+ +VN D N T + A +GH +V K+L E
Sbjct: 117 LHLAAWKGDAQIVRLLIHQGPSHTRVNEQNND--NETALHCAAQYGHTEVVKVLLE 170
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 47.8 bits (112), Expect = 3e-05
Identities = 31/85 (36%), Positives = 47/85 (55%), Gaps = 4/85 (4%)
Query: 560 AAYTGDVSALRR-FALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLL-EACKVNPFPKD 617
AA GD + + R A + D++ D RTALH+A A GHV+VV L+ C+++ K+
Sbjct: 40 AAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKE 99
Query: 618 RWNNTPMDEALHFGHHDVFKILQEY 642
N TP+ +A+H IL E+
Sbjct: 100 --NRTPLIQAVHCQEEACAVILLEH 122
>gi|39812133 ankyrin repeat domain 2 isoform a [Homo sapiens]
Length = 360
Score = 47.4 bits (111), Expect = 4e-05
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 558 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 617
L AA G + + +F + D RTALH A+ EGH+E+++ LL+ F +D
Sbjct: 153 LKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDF-QD 211
Query: 618 RWNNTPMDEALHFGHHDVFKILQEY 642
R + T M A GH +V K+LQ +
Sbjct: 212 RLDCTAMHWACRGGHLEVVKLLQSH 236
Score = 35.0 bits (79), Expect = 0.22
Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 559 FAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVK-FLLEACKVNPFPKD 617
+A G + ++ D RD T LHVA G VE+V+ FL ++N +D
Sbjct: 220 WACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEIN--ARD 277
Query: 618 RWNNTPMDEALHFGHHDVFKIL 639
R +T + +A+ + + K+L
Sbjct: 278 REGDTALHDAVRLNRYKIIKLL 299
Score = 31.2 bits (69), Expect = 3.2
Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
Query: 546 GGDQRVKSVI---NLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVV 602
G D V+ + L A TG V + F +++ RD + TALH A +++
Sbjct: 237 GADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLGLEINARDREGDTALHDAVRLNRYKII 296
Query: 603 KFLL 606
K LL
Sbjct: 297 KLLL 300
>gi|194018403 ankyrin repeat domain 2 isoform b [Homo sapiens]
Length = 327
Score = 47.4 bits (111), Expect = 4e-05
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 558 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 617
L AA G + + +F + D RTALH A+ EGH+E+++ LL+ F +D
Sbjct: 153 LKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDF-QD 211
Query: 618 RWNNTPMDEALHFGHHDVFKILQEY 642
R + T M A GH +V K+LQ +
Sbjct: 212 RLDCTAMHWACRGGHLEVVKLLQSH 236
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 46.2 bits (108), Expect = 1e-04
Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
Query: 548 DQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE 607
D KS ++ +AA +V A + + + +D T L +AA EG E K LL+
Sbjct: 1974 DDHGKSALH--WAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLD 2031
Query: 608 ACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQG 650
N D + P D A HHD+ ++L EY V +P G
Sbjct: 2032 HF-ANRDITDHMDRLPRDVARDRMHHDIVRLLDEYNVTPSPPG 2073
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 46.2 bits (108), Expect = 1e-04
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 4/85 (4%)
Query: 560 AAYTGDVSALRR-FALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLL-EACKVNPFPKD 617
AA GD + + R A + D++ D RTALH+A GHV+VV L+ C+++ K+
Sbjct: 40 AAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKE 99
Query: 618 RWNNTPMDEALHFGHHDVFKILQEY 642
N TP+ +A+H IL E+
Sbjct: 100 --NRTPLIQAVHCQEEACAVILLEH 122
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 46.2 bits (108), Expect = 1e-04
Identities = 30/85 (35%), Positives = 47/85 (55%), Gaps = 4/85 (4%)
Query: 560 AAYTGDVSALRR-FALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLL-EACKVNPFPKD 617
AA GD + + R A + +++ D RTALH+A A GHV+VV L+ C+++ K+
Sbjct: 40 AAVKGDAAEVERCLARRSGELDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKE 99
Query: 618 RWNNTPMDEALHFGHHDVFKILQEY 642
N TP+ +A+H IL E+
Sbjct: 100 --NRTPLIQAVHCQEEACAVILLEH 122
>gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo
sapiens]
Length = 226
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/81 (38%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
Query: 561 AYTGDVSALRRFALSAMDMEQR-DYDSRTALHVAAAEGHVEVVKFLLE-ACKVNPFPKDR 618
AY+G + L+ L+ + R D DSRTALH A + GH E+V+FLL+ VN KD
Sbjct: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVN--DKDD 71
Query: 619 WNNTPMDEALHFGHHDVFKIL 639
+P+ A G ++ K L
Sbjct: 72 AGWSPLHIAASAGRDEIVKAL 92
Score = 32.0 bits (71), Expect = 1.9
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 588 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYT 647
T LH AA++ E+ LLE NP KD + T M A G+ + IL Y+
Sbjct: 108 TPLHYAASKNRHEIAVMLLEG-GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTN 166
Query: 648 PQGDSDN 654
Q N
Sbjct: 167 IQDTEGN 173
>gi|28605137 proteasome 26S non-ATPase subunit 10 isform 2 [Homo
sapiens]
Length = 151
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/81 (38%), Positives = 44/81 (54%), Gaps = 4/81 (4%)
Query: 561 AYTGDVSALRRFALSAMDMEQR-DYDSRTALHVAAAEGHVEVVKFLLE-ACKVNPFPKDR 618
AY+G + L+ L+ + R D DSRTALH A + GH E+V+FLL+ VN KD
Sbjct: 14 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVN--DKDD 71
Query: 619 WNNTPMDEALHFGHHDVFKIL 639
+P+ A G ++ K L
Sbjct: 72 AGWSPLHIAASAGRDEIVKAL 92
>gi|34304381 inversin isoform a [Homo sapiens]
Length = 1065
Score = 45.8 bits (107), Expect = 1e-04
Identities = 42/131 (32%), Positives = 57/131 (43%), Gaps = 10/131 (7%)
Query: 530 YDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALR--RFALSAMDMEQ----RD 583
Y+N H + G V+ I L +AA D SA+ R L A E +D
Sbjct: 159 YNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQD 218
Query: 584 YDSRTALHVAAAEGHVEVVKFL--LEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
Y+ RT LH A A+G+V VV L E+C + + D TP+ A GH + +L E
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESCNITSY--DNLFRTPLHWAALLGHAQIVHLLLE 276
Query: 642 YQVQYTPQGDS 652
T DS
Sbjct: 277 RNKSGTIPSDS 287
Score = 44.7 bits (104), Expect = 3e-04
Identities = 32/94 (34%), Positives = 42/94 (44%), Gaps = 3/94 (3%)
Query: 548 DQRVKSVINLLFAAYTGDVSALRRFAL--SAMDMEQRDYDSRTALHVAAAEGHVEVVKFL 605
D ++ + ++AA G LR S +D+ D TALH AA GHV VK L
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 606 LEACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 639
LE D +TP+ A GH DV + L
Sbjct: 377 LEN-NAQVDATDVMKHTPLFRACEMGHKDVIQTL 409
Score = 43.1 bits (100), Expect = 8e-04
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 560 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 619
AAY G ++ + + D +D + RTALH + G+++ +K LL+ FP
Sbjct: 463 AAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA---AFPNQME 519
Query: 620 NN----TPMDEALHFGHHDVFKILQEY 642
NN TP+D AL H+V + + E+
Sbjct: 520 NNEERYTPLDYALLGERHEVIQFMLEH 546
Score = 37.4 bits (85), Expect = 0.045
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 7/79 (8%)
Query: 584 YDS--RTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
YD+ RT LH AA GH ++V LLE K P D TP+ A + K+ +
Sbjct: 251 YDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLK 310
Query: 642 YQVQYTPQGDSDNGKENQT 660
+ P D+ E +T
Sbjct: 311 H-----PSVKDDSDLEGRT 324
Score = 35.8 bits (81), Expect = 0.13
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 583 DYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
D D + LH AA G+ +V + L+E K+NP +D TP+ A + G+ + +L E
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 33.9 bits (76), Expect = 0.50
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 578 DMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPM 624
D+ + D+ RTALH+AA +G+ +K LL + N KD TP+
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPL 118
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 616
L +AA G+ + + ++ +DY RT L AA G++ + L+E +P +
Sbjct: 427 LHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMEN-NADPNIQ 485
Query: 617 DRWNNTPMDEALHFGHHDVFKILQEY----------QVQYTPQGDSDNGKENQTVHKNLD 666
D+ T + + + G+ D K+L ++ + +YTP + G+ ++ + L+
Sbjct: 486 DKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Score = 30.0 bits (66), Expect = 7.2
Identities = 32/137 (23%), Positives = 54/137 (39%), Gaps = 16/137 (11%)
Query: 525 CNFHNYDNL----RHFAKKLD---------PRREGGD--QRVKSVINLLFAAYTGDVSAL 569
CN +YDNL H+A L R + G + L +AA + +
Sbjct: 246 CNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETV 305
Query: 570 RRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE-ACKVNPFPKDRWNNTPMDEAL 628
+ F + D + RT+ AA +G +V++ +L ++ D++ T + A
Sbjct: 306 KVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAA 365
Query: 629 HFGHHDVFKILQEYQVQ 645
GH K+L E Q
Sbjct: 366 LSGHVSTVKLLLENNAQ 382
>gi|34304379 inversin isoform b [Homo sapiens]
Length = 895
Score = 45.8 bits (107), Expect = 1e-04
Identities = 42/131 (32%), Positives = 57/131 (43%), Gaps = 10/131 (7%)
Query: 530 YDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALR--RFALSAMDMEQ----RD 583
Y+N H + G V+ I L +AA D SA+ R L A E +D
Sbjct: 159 YNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQD 218
Query: 584 YDSRTALHVAAAEGHVEVVKFL--LEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
Y+ RT LH A A+G+V VV L E+C + + D TP+ A GH + +L E
Sbjct: 219 YEGRTPLHFAVADGNVTVVDVLTSYESCNITSY--DNLFRTPLHWAALLGHAQIVHLLLE 276
Query: 642 YQVQYTPQGDS 652
T DS
Sbjct: 277 RNKSGTIPSDS 287
Score = 44.7 bits (104), Expect = 3e-04
Identities = 32/94 (34%), Positives = 42/94 (44%), Gaps = 3/94 (3%)
Query: 548 DQRVKSVINLLFAAYTGDVSALRRFAL--SAMDMEQRDYDSRTALHVAAAEGHVEVVKFL 605
D ++ + ++AA G LR S +D+ D TALH AA GHV VK L
Sbjct: 317 DSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 606 LEACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 639
LE D +TP+ A GH DV + L
Sbjct: 377 LEN-NAQVDATDVMKHTPLFRACEMGHKDVIQTL 409
Score = 43.1 bits (100), Expect = 8e-04
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 560 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 619
AAY G ++ + + D +D + RTALH + G+++ +K LL+ FP
Sbjct: 463 AAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFA---AFPNQME 519
Query: 620 NN----TPMDEALHFGHHDVFKILQEY 642
NN TP+D AL H+V + + E+
Sbjct: 520 NNEERYTPLDYALLGERHEVIQFMLEH 546
Score = 37.4 bits (85), Expect = 0.045
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 7/79 (8%)
Query: 584 YDS--RTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
YD+ RT LH AA GH ++V LLE K P D TP+ A + K+ +
Sbjct: 251 YDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLK 310
Query: 642 YQVQYTPQGDSDNGKENQT 660
+ P D+ E +T
Sbjct: 311 H-----PSVKDDSDLEGRT 324
Score = 35.8 bits (81), Expect = 0.13
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 583 DYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
D D + LH AA G+ +V + L+E K+NP +D TP+ A + G+ + +L E
Sbjct: 420 DQDGHSLLHWAALGGNADVCQILIEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLME 477
Score = 33.9 bits (76), Expect = 0.50
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 578 DMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPM 624
D+ + D+ RTALH+AA +G+ +K LL + N KD TP+
Sbjct: 73 DVNKTDHSQRTALHLAAQKGNYRFMKLLLTR-RANWMQKDLEEMTPL 118
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 616
L +AA G+ + + ++ +DY RT L AA G++ + L+E +P +
Sbjct: 427 LHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMEN-NADPNIQ 485
Query: 617 DRWNNTPMDEALHFGHHDVFKILQEY----------QVQYTPQGDSDNGKENQTVHKNLD 666
D+ T + + + G+ D K+L ++ + +YTP + G+ ++ + L+
Sbjct: 486 DKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Score = 30.0 bits (66), Expect = 7.2
Identities = 32/137 (23%), Positives = 54/137 (39%), Gaps = 16/137 (11%)
Query: 525 CNFHNYDNL----RHFAKKLD---------PRREGGD--QRVKSVINLLFAAYTGDVSAL 569
CN +YDNL H+A L R + G + L +AA + +
Sbjct: 246 CNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETV 305
Query: 570 RRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE-ACKVNPFPKDRWNNTPMDEAL 628
+ F + D + RT+ AA +G +V++ +L ++ D++ T + A
Sbjct: 306 KVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAA 365
Query: 629 HFGHHDVFKILQEYQVQ 645
GH K+L E Q
Sbjct: 366 LSGHVSTVKLLLENNAQ 382
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1
isoform 1 [Homo sapiens]
Length = 1298
Score = 45.4 bits (106), Expect = 2e-04
Identities = 26/83 (31%), Positives = 46/83 (55%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 616
L+ AA + A++ + ++ +D + T LH+AA +GH EVV++LL +++ +
Sbjct: 810 LMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQ 869
Query: 617 DRWNNTPMDEALHFGHHDVFKIL 639
D TPM A + H D+ K+L
Sbjct: 870 DDGGWTPMIWATEYKHVDLVKLL 892
Score = 39.3 bits (90), Expect = 0.012
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 3/100 (3%)
Query: 540 LDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHV 599
+DP + Q +S ++ AA G V + +++ D RT L AA H+
Sbjct: 762 IDPNFKMEHQNKRSPLHA--AAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHL 819
Query: 600 EVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKIL 639
E VK+L++A + PKD +T + A GH++V + L
Sbjct: 820 EAVKYLIKAGALVD-PKDAEGSTCLHLAAKKGHYEVVQYL 858
>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
Length = 1429
Score = 45.1 bits (105), Expect = 2e-04
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 560 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 619
AA+ G V ++ ++ TAL +AA EGH++VV+ LLE +P D++
Sbjct: 1019 AAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEH-GADPNHADQF 1077
Query: 620 NNTPMDEALHFGHHDVFKILQEY 642
T M A GH + K+L++Y
Sbjct: 1078 GRTAMRVAAKNGHSQIIKLLEKY 1100
Score = 41.2 bits (95), Expect = 0.003
Identities = 31/91 (34%), Positives = 44/91 (48%), Gaps = 8/91 (8%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVA-----AAEGHVEVVKFLLE-ACK 610
L+ AAY G + ++ D D RTAL VA A++GH VV L++ +
Sbjct: 681 LIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAE 740
Query: 611 VNPFPKDRWNNTPMDEALHFGHHDVFKILQE 641
V+ KD TP+ A + GH DV +L E
Sbjct: 741 VDHCDKD--GMTPLLVAAYEGHVDVVDLLLE 769
Score = 38.9 bits (89), Expect = 0.016
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 3/81 (3%)
Query: 560 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE-ACKVNPFPKDR 618
AAY+G + + D+E D T L +AA +GH +VV L+ +N +D
Sbjct: 552 AAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDG 611
Query: 619 WNNTPMDEALHFGHHDVFKIL 639
W T + A GH +V L
Sbjct: 612 W--TALRSAAWGGHTEVVSAL 630
Score = 38.5 bits (88), Expect = 0.020
Identities = 30/87 (34%), Positives = 37/87 (42%), Gaps = 1/87 (1%)
Query: 553 SVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVN 612
SV L A G S + +++ D D T L VAA EGHV+VV LLE +
Sbjct: 715 SVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEG-GAD 773
Query: 613 PFPKDRWNNTPMDEALHFGHHDVFKIL 639
D TP+ A GH V L
Sbjct: 774 VDHTDNNGRTPLLAAASMGHASVVNTL 800
Score = 38.5 bits (88), Expect = 0.020
Identities = 31/97 (31%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 616
LL AA G S + ++ D + RT L +A+A+G+VEVV+ LL+ ++ +
Sbjct: 785 LLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDR-GLDENHR 843
Query: 617 DRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSD 653
D TP+ A GH + + L E Q T + D+D
Sbjct: 844 DDAGWTPLHMAAFEGHRLICEALIE-QGARTNEIDND 879
Score = 38.1 bits (87), Expect = 0.026
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 560 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE-ACKVNPFPKDR 618
AA+ G + + + ++ D DSRTAL AA GH ++V LL+ +VN D
Sbjct: 618 AAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVN--KADN 675
Query: 619 WNNTPMDEALHFGHHDVFKILQEY 642
T + A + GH ++ + L ++
Sbjct: 676 EGRTALIAAAYMGHREIVEHLLDH 699
Score = 37.7 bits (86), Expect = 0.035
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 616
L A ++ F + ++E D + RTALHV+ +GH+E+V+ L+ A +
Sbjct: 950 LYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLI-AYHADVNAA 1008
Query: 617 DRWNNTPMDEALHFGHHDVFKILQEY 642
D + + A GH V ++L E+
Sbjct: 1009 DNEKRSALQSAAWQGHVKVVQLLIEH 1034
Score = 37.4 bits (85), Expect = 0.045
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 555 INLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFL 605
I + A+ G ++ + +++QR YD R AL VAA EGH ++V+ L
Sbjct: 882 IPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELL 932
Score = 35.4 bits (80), Expect = 0.17
Identities = 20/50 (40%), Positives = 25/50 (50%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLL 606
LL AAY G V + D++ D + RT L AA+ GH VV LL
Sbjct: 752 LLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLL 801
Score = 32.3 bits (72), Expect = 1.5
Identities = 19/64 (29%), Positives = 27/64 (42%), Gaps = 7/64 (10%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFL-------LEAC 609
L AA G + ++ D D RTA+ VAA GH +++K L L C
Sbjct: 1049 LCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLNGC 1108
Query: 610 KVNP 613
+P
Sbjct: 1109 SPSP 1112
Score = 31.6 bits (70), Expect = 2.5
Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA-CKVNPFP 615
L AA G + ++ D D TAL AA GH EVV LL A KV+
Sbjct: 582 LTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCAD 641
Query: 616 KDRWNNTPMDEALHFGHHDV 635
D + T + A GH D+
Sbjct: 642 AD--SRTALRAAAWGGHEDI 659
>gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Homo
sapiens]
Length = 1194
Score = 44.7 bits (104), Expect = 3e-04
Identities = 26/83 (31%), Positives = 40/83 (48%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 616
L+ A G + ++ D+ +D + TAL A+ GHVE+VK LL N +
Sbjct: 1080 LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLE 1139
Query: 617 DRWNNTPMDEALHFGHHDVFKIL 639
D +T + AL GH D+ +L
Sbjct: 1140 DNDGSTALSIALEAGHKDIAVLL 1162
>gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Homo
sapiens]
Length = 1352
Score = 44.7 bits (104), Expect = 3e-04
Identities = 26/83 (31%), Positives = 40/83 (48%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 616
L+ A G + ++ D+ +D + TAL A+ GHVE+VK LL N +
Sbjct: 1238 LMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLE 1297
Query: 617 DRWNNTPMDEALHFGHHDVFKIL 639
D +T + AL GH D+ +L
Sbjct: 1298 DNDGSTALSIALEAGHKDIAVLL 1320
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 44.7 bits (104), Expect = 3e-04
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 616
L FAA G + + +++ RD LH A + GH EVV LL +P +
Sbjct: 62 LHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRH-GADPNAR 120
Query: 617 DRWNNTPMDEALHFGHHDVFKILQEYQVQYT 647
D WN TP+ EA G DV +L ++ + T
Sbjct: 121 DNWNYTPLHEAAIKGKIDVCIVLLQHGAEPT 151
Score = 43.1 bits (100), Expect = 8e-04
Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 4/88 (4%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSR--TALHVAAAEGHVEVVKFLLEACKVNPF 614
LL AA GDV +++ + + RD + R T LH AA V VV++LL+ +
Sbjct: 496 LLEAAKAGDVETVKKLC-TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQH-GADVH 553
Query: 615 PKDRWNNTPMDEALHFGHHDVFKILQEY 642
KD+ P+ A +GH++V ++L ++
Sbjct: 554 AKDKGGLVPLHNACSYGHYEVAELLVKH 581
Score = 40.4 bits (93), Expect = 0.005
Identities = 29/99 (29%), Positives = 44/99 (44%), Gaps = 3/99 (3%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE-ACKVNPFP 615
L FAA VS + D+ +D LH A + GH EV + L++ VN
Sbjct: 530 LHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVN--V 587
Query: 616 KDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDN 654
D W TP+ EA G +++ K+L ++ T + N
Sbjct: 588 ADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGN 626
Score = 37.0 bits (84), Expect = 0.059
Identities = 31/104 (29%), Positives = 47/104 (45%), Gaps = 11/104 (10%)
Query: 557 LLFAAYTGDVSALRRFALSAMDMEQRDYDSR--TALHVAAAEGHVEVVKFLLEACKVNPF 614
L A GDV ++R ++ + RD R T LH AA G +VV++LL+ N
Sbjct: 28 LFEACRNGDVERVKRL-VTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQN-GANVQ 85
Query: 615 PKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKEN 658
+D P+ A FGH +V +L + G N ++N
Sbjct: 86 ARDDGGLIPLHNACSFGHAEVVNLLLRH-------GADPNARDN 122
Score = 34.7 bits (78), Expect = 0.29
Identities = 39/138 (28%), Positives = 56/138 (40%), Gaps = 21/138 (15%)
Query: 520 DLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVIN----------------LLFAAYT 563
DLV + D LR A LD ++G RVK + + L AA
Sbjct: 630 DLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGY 689
Query: 564 GDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLE--ACKVNPFPKDRWNN 621
++ D+ +D LH AA+ GHV+V L++ AC VN D+W
Sbjct: 690 NNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNAC-VN--ATDKWAF 746
Query: 622 TPMDEALHFGHHDVFKIL 639
TP+ EA G + +L
Sbjct: 747 TPLHEAAQKGRTQLCALL 764
Score = 34.3 bits (77), Expect = 0.38
Identities = 17/55 (30%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 588 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEY 642
T LH+AA V++V+ LL+ + KD+ + P+ A +GH++V ++L ++
Sbjct: 213 TPLHLAAGYNRVKIVQLLLQH-GADVHAKDKGDLVPLHNACSYGHYEVTELLVKH 266
Score = 33.9 bits (76), Expect = 0.50
Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 7/125 (5%)
Query: 520 DLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDM 579
+L+ N + + L+ D R + ++L AA V ++ D+
Sbjct: 180 ELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHL--AAGYNRVKIVQLLLQHGADV 237
Query: 580 EQRDYDSRTALHVAAAEGHVEVVKFLLE--ACKVNPFPKDRWNNTPMDEALHFGHHDVFK 637
+D LH A + GH EV + L++ AC VN D W TP+ EA +V
Sbjct: 238 HAKDKGDLVPLHNACSYGHYEVTELLVKHGAC-VNAM--DLWQFTPLHEAASKNRVEVCS 294
Query: 638 ILQEY 642
+L Y
Sbjct: 295 LLLSY 299
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,621,714
Number of Sequences: 37866
Number of extensions: 1427615
Number of successful extensions: 9874
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 220
Number of HSP's successfully gapped in prelim test: 322
Number of HSP's that attempted gapping in prelim test: 7483
Number of HSP's gapped (non-prelim): 2571
length of query: 669
length of database: 18,247,518
effective HSP length: 109
effective length of query: 560
effective length of database: 14,120,124
effective search space: 7907269440
effective search space used: 7907269440
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.