Guide to the Human Genome
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Search of human proteins with 156071450

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156071450 nardilysin isoform a [Homo sapiens]
         (1219 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156071450 nardilysin isoform a [Homo sapiens]                     2475   0.0  
gi|156071452 nardilysin isoform b [Homo sapiens]                     2258   0.0  
gi|155969707 insulin-degrading enzyme [Homo sapiens]                  544   e-154
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    66   2e-10
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    59   2e-08
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...    57   1e-07
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...    57   1e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens]               57   1e-07
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    57   1e-07
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    57   1e-07
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    57   1e-07
gi|55956788 nucleolin [Homo sapiens]                                   56   2e-07
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          56   2e-07
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    56   2e-07
gi|170763500 SET translocation (myeloid leukemia-associated) iso...    56   2e-07
gi|170763498 SET translocation (myeloid leukemia-associated) iso...    56   2e-07
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      54   7e-07
gi|115529449 upstream binding transcription factor, RNA polymera...    54   1e-06
gi|115529451 upstream binding transcription factor, RNA polymera...    54   1e-06
gi|7657671 upstream binding transcription factor, RNA polymerase...    54   1e-06
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    53   2e-06
gi|42740903 MTERF domain containing 2 [Homo sapiens]                   52   3e-06
gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens]    52   3e-06
gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens]    52   3e-06
gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens]    52   3e-06
gi|157743245 WD repeat domain 43 [Homo sapiens]                        52   3e-06
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       52   3e-06
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    52   3e-06
gi|18093112 ABT1-associated protein [Homo sapiens]                     52   3e-06
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           52   5e-06

>gi|156071450 nardilysin isoform a [Homo sapiens]
          Length = 1219

 Score = 2475 bits (6415), Expect = 0.0
 Identities = 1219/1219 (100%), Positives = 1219/1219 (100%)

Query: 1    MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC 60
            MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC
Sbjct: 1    MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC 60

Query: 61   SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN 120
            SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN
Sbjct: 61   SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN 120

Query: 121  GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD 180
            GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD
Sbjct: 121  GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD 180

Query: 181  EHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLFLLWSKLTDRLWFKSTYSKMSSTLL 240
            EHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLFLLWSKLTDRLWFKSTYSKMSSTLL
Sbjct: 181  EHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLFLLWSKLTDRLWFKSTYSKMSSTLL 240

Query: 241  VETRNLYGVVGAESRSAPVQHLAGWQAEEQQGETDTVLSAAALCVGVGSFADPDDLPGLA 300
            VETRNLYGVVGAESRSAPVQHLAGWQAEEQQGETDTVLSAAALCVGVGSFADPDDLPGLA
Sbjct: 241  VETRNLYGVVGAESRSAPVQHLAGWQAEEQQGETDTVLSAAALCVGVGSFADPDDLPGLA 300

Query: 301  HFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ 360
            HFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ
Sbjct: 301  HFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ 360

Query: 361  FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLK 420
            FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLK
Sbjct: 361  FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLK 420

Query: 421  HEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPN 480
            HEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPN
Sbjct: 421  HEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPN 480

Query: 481  FGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS 540
            FGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS
Sbjct: 481  FGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS 540

Query: 541  ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKML 600
            ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKML
Sbjct: 541  ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKML 600

Query: 601  QKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKP 660
            QKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKP
Sbjct: 601  QKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKP 660

Query: 661  EVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP 720
            EVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP
Sbjct: 661  EVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP 720

Query: 721  DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLIS 780
            DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLIS
Sbjct: 721  DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLIS 780

Query: 781  PLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPL 840
            PLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPL
Sbjct: 781  PLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPL 840

Query: 841  LFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY 900
            LFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY
Sbjct: 841  LFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY 900

Query: 901  QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPV 960
            QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPV
Sbjct: 901  QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPV 960

Query: 961  QFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFL 1020
            QFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFL
Sbjct: 961  QFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFL 1020

Query: 1021 RTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEE 1080
            RTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEE
Sbjct: 1021 RTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEE 1080

Query: 1081 AFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWF 1140
            AFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWF
Sbjct: 1081 AFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWF 1140

Query: 1141 KAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPIT 1200
            KAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPIT
Sbjct: 1141 KAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPIT 1200

Query: 1201 DIRAFTTTLNLLPYHKIVK 1219
            DIRAFTTTLNLLPYHKIVK
Sbjct: 1201 DIRAFTTTLNLLPYHKIVK 1219


>gi|156071452 nardilysin isoform b [Homo sapiens]
          Length = 1151

 Score = 2258 bits (5850), Expect = 0.0
 Identities = 1131/1219 (92%), Positives = 1139/1219 (93%), Gaps = 68/1219 (5%)

Query: 1    MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC 60
            MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC
Sbjct: 1    MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC 60

Query: 61   SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN 120
            SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN
Sbjct: 61   SCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQN 120

Query: 121  GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDD 180
            GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFD 
Sbjct: 121  GLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFD- 179

Query: 181  EHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLFLLWSKLTDRLWFKSTYSKMSSTLL 240
                  D  D++L+            TE  +L+ L                         
Sbjct: 180  ------DEHDDDLD------------TEDNELEEL------------------------- 196

Query: 241  VETRNLYGVVGAESRSAPVQHLAGWQAEEQQGETDTVLSAAALCVGVGSFADPDDLPGLA 300
                        E R+            E + +T    SAAALCVGVGSFADPDDLPGLA
Sbjct: 197  ------------EERA------------EARKKTTEKQSAAALCVGVGSFADPDDLPGLA 232

Query: 301  HFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ 360
            HFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ
Sbjct: 233  HFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQ 292

Query: 361  FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLK 420
            FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLK
Sbjct: 293  FFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLK 352

Query: 421  HEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPN 480
            HEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPN
Sbjct: 353  HEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPN 412

Query: 481  FGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS 540
            FGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS
Sbjct: 413  FGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGS 472

Query: 541  ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKML 600
            ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKML
Sbjct: 473  ILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKML 532

Query: 601  QKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKP 660
            QKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKP
Sbjct: 533  QKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKP 592

Query: 661  EVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP 720
            EVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP
Sbjct: 593  EVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNP 652

Query: 721  DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLIS 780
            DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLIS
Sbjct: 653  DLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLIS 712

Query: 781  PLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPL 840
            PLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPL
Sbjct: 713  PLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPL 772

Query: 841  LFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY 900
            LFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY
Sbjct: 773  LFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKY 832

Query: 901  QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPV 960
            QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPV
Sbjct: 833  QALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPV 892

Query: 961  QFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFL 1020
            QFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFL
Sbjct: 893  QFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFL 952

Query: 1021 RTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEE 1080
            RTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEE
Sbjct: 953  RTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEE 1012

Query: 1081 AFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWF 1140
            AFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWF
Sbjct: 1013 AFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWF 1072

Query: 1141 KAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPIT 1200
            KAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPIT
Sbjct: 1073 KAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPIT 1132

Query: 1201 DIRAFTTTLNLLPYHKIVK 1219
            DIRAFTTTLNLLPYHKIVK
Sbjct: 1133 DIRAFTTTLNLLPYHKIVK 1151


>gi|155969707 insulin-degrading enzyme [Homo sapiens]
          Length = 1019

 Score =  544 bits (1401), Expect = e-154
 Identities = 316/936 (33%), Positives = 507/936 (54%), Gaps = 20/936 (2%)

Query: 229  KSTYSKMSSTLLVETRNLYGVVGAESRSAPVQHLAGWQAEEQQGETDTVLSAAALCVGVG 288
            K TYSKM++  +    N       + R      LA         +  T  S+AAL V +G
Sbjct: 36   KKTYSKMNNPAIKRIGNHITKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIG 95

Query: 289  SFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQR 348
            S +DP ++ GL+HF EHM+F+G+ KYP EN +  FL +H GS NA T  E T + FDV  
Sbjct: 96   SLSDPPNIAGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSH 155

Query: 349  KYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPM 408
            ++ + ALDR+AQFF+ PL      DREV AVDSE++    +DA R   L  +   P HP 
Sbjct: 156  EHLEGALDRFAQFFLCPLFDESCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPF 215

Query: 409  GKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIF 468
             KF  GN  TL+  P +  ID    L +F   YYSS+ M + V  +E+LD L   V ++F
Sbjct: 216  SKFGTGNKYTLETRPNQEGIDVRQELLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLF 275

Query: 469  SQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHY 528
            S++ N  +P P F     PF      +LY++VPI+ I  L +T+ +P  Q++Y+  P HY
Sbjct: 276  SEVENKNVPLPEFPE--HPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHY 333

Query: 529  ISWLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYE 588
            +  L+GHEG GS+LS L+ K W   L GG  E        +  F I++ LT+EG  H  +
Sbjct: 334  LGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGA----RGFMFFIINVDLTEEGLLHVED 389

Query: 589  VAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDI 648
            +   +FQY++ L+  GP++ +F+E + +    F ++++  P  Y   +   +  YPL+++
Sbjct: 390  IILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGILHYYPLEEV 449

Query: 649  LTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSW 708
            LT + LL E++P++I   L++L P+   + ++S + EGK D  E+W+GTQY  E I +  
Sbjct: 450  LTAEYLLEEFRPDLIEMVLDKLRPENVRVAIVSKSFEGKTDRTEEWYGTQYKQEAIPDEV 509

Query: 709  AELWNSNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFK 768
             + W  N +LN    LP +N++I T+F +   +   T YP  I +T    LW+K+D+KF 
Sbjct: 510  IKKW-QNADLNGKFKLPTKNEFIPTNFEILPLEKEATPYPALIKDTAMSKLWFKQDDKFF 568

Query: 769  IPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLI 828
            +PKA + F   SP       +  +  +++ +L  +L E AY A++A L Y L    +G+ 
Sbjct: 569  LPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMY 628

Query: 829  IRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILI-KPETLAKDVRLL 887
            + VKG+N K P+L + II+ +A F      F +I E   ++  N    +P   A     L
Sbjct: 629  LSVKGYNDKQPILLKKIIEKMATFEIDEKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRL 688

Query: 888  ILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVD 947
            ++    W+  D+ +  +D ++L  L +F+ +  S+L +E L+ GN+T   ++  ++ V D
Sbjct: 689  LMTEVAWTK-DELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGIMQMVED 747

Query: 948  KL----NFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYT 1003
             L    + KPL     V+++ V+LP        +  N+   N  + +YYQ+  +S  E  
Sbjct: 748  TLIEHAHTKPLLPSQLVRYREVQLPDRGWFV-YQQRNEVHNNCGIEIYYQTDMQSTSENM 806

Query: 1004 LMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKI 1063
             +EL    + EPCF+ LRTK+ LGY V+   R  +GI G    + ++   +    ++ ++
Sbjct: 807  FLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPH---YLESRV 863

Query: 1064 EEFLSSFEEKIENLTEEAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAH 1123
            E FL + E+ IE++TEEAF   + AL   +  +   L  E  + W E+++QQY FDR   
Sbjct: 864  EAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNFDRDNT 923

Query: 1124 EIEALKSFSKSDLVNWFK---AHRGPGSKMLSVHVV 1156
            E+  LK+ +K D++ ++K   A   P    +SVHV+
Sbjct: 924  EVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVL 959



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 15/27 (55%), Positives = 21/27 (77%)

Query: 103 IVKSPSDPKQYRYIKLQNGLQALLISD 129
           I KSP D ++YR ++L NG++ LLISD
Sbjct: 54  ITKSPEDKREYRGLELANGIKVLLISD 80


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 30/74 (40%), Positives = 54/74 (72%), Gaps = 1/74 (1%)

Query: 142 DDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAE 201
           ++EEEEE EEEEE+++E+   E E+D+EE F++E+E ++E +++ + E+ ELEE EE  E
Sbjct: 891 EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE-EEEEE 949

Query: 202 ARKKTTEKQQLQSL 215
             ++  E ++++ L
Sbjct: 950 DEEEEEELEEVEDL 963



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 21/53 (39%), Positives = 35/53 (66%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195
           +EEEEE EE EE+ +E+ G   E+++EE  ++E+E ++  D +  T   E+EE
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 22/79 (27%)

Query: 139 NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDE---FDDEHDDD---LDTEDNE 192
           N++D+EEEEE EEEEE                  ++E+E   F++E +D+    + E+ E
Sbjct: 884 NSSDEEEEEEEEEEEE----------------EEEEEEEEEDFEEEEEDEEEYFEEEEEE 927

Query: 193 LEELEERAEARKKTTEKQQ 211
            EE EE  E  +   E+++
Sbjct: 928 EEEFEEEFEEEEGELEEEE 946



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 15/53 (28%), Positives = 31/53 (58%)

Query: 164 IEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLF 216
           I   DEE  ++E+E ++E +++ + ED E EE +E     ++  E+++ +  F
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEF 935


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 31/79 (39%), Positives = 51/79 (64%), Gaps = 3/79 (3%)

Query: 134 EGKTGNTTDDEEEEEVEEEE--EDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDN 191
           E + G   +DE++E+ EEEE  E+DDED   E ++DD+E  ++E+EF  + +D+ + ED 
Sbjct: 170 EDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDE 229

Query: 192 ELEELEERAEARKKTTEKQ 210
           E EE   + E RK+ T+ +
Sbjct: 230 E-EEEGGKGEKRKRETDDE 247



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 7/85 (8%)

Query: 134 EGKTGNTTDDEEEEEVEEEEEDDDEDSGAE------IEDDDEEGFDDEDEFDDEHDD-DL 186
           + +     ++EE+EE E+EE++DDED   E       ED+D EG +D+DE  +E ++  L
Sbjct: 159 DAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGL 218

Query: 187 DTEDNELEELEERAEARKKTTEKQQ 211
           D ED + +E EE  E  K    K++
Sbjct: 219 DEEDEDEDEDEEEEEGGKGEKRKRE 243



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 31/81 (38%), Positives = 47/81 (58%), Gaps = 9/81 (11%)

Query: 122 LQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDE 181
           L  L   D  + E +    +D E +   EEEE+++ ED   E ++DDE+G  +E+EFD+E
Sbjct: 139 LPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGED---EEDEDDEDG--EEEEFDEE 193

Query: 182 HDDDLDTE----DNELEELEE 198
            D+D D E    D+E+ E EE
Sbjct: 194 DDEDEDVEGDEDDDEVSEEEE 214



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 24/70 (34%), Positives = 43/70 (61%), Gaps = 1/70 (1%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFD-DEHDDDLDTEDNELEELEERAE 201
           D  + E +E  + D E  G + E++DEEG D+EDE D D  +++ D ED+E E++E   +
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDED 205

Query: 202 ARKKTTEKQQ 211
             + + E+++
Sbjct: 206 DDEVSEEEEE 215



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 21/49 (42%), Positives = 32/49 (65%), Gaps = 6/49 (12%)

Query: 143 DEEEEEVEEEEED---DDEDSGAEIEDDDEEGFDDED---EFDDEHDDD 185
           DE+++EV EEEE+   D+ED   + ++++EEG   E    E DDE +DD
Sbjct: 203 DEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 29/112 (25%), Positives = 43/112 (38%), Gaps = 20/112 (17%)

Query: 64  DLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDP-EIVKSPSDPKQYRYIKLQNGL 122
           D + +G D  E         DE +E+G         D  E V+   D             
Sbjct: 159 DAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDD------------ 206

Query: 123 QALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDD 174
                 ++S  E + G   +DE+E+E EEEEE    +      + D+EG DD
Sbjct: 207 -----DEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEK--RKRETDDEGEDD 251


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 30/81 (37%), Positives = 50/81 (61%), Gaps = 3/81 (3%)

Query: 134 EGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIE--DDDEEGFDDEDEFD-DEHDDDLDTED 190
           E + G    D E E+ EEEE D++ED   ++E  DD +E  ++E+EF  D+ +DD D ++
Sbjct: 190 EDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDE 249

Query: 191 NELEELEERAEARKKTTEKQQ 211
           +E EE   + E RK+ T+ ++
Sbjct: 250 DEEEEESGKGENRKRETDDEE 270



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 23/73 (31%), Positives = 43/73 (58%), Gaps = 7/73 (9%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDD----DLDTEDNELEELEE 198
           D  + E +E  + D +  G + E++DEEG   EDE D E++D    +LD E++E E++E 
Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEEG---EDEKDXENEDGEEEELDEEEDEDEDVEG 222

Query: 199 RAEARKKTTEKQQ 211
             +  + + E+++
Sbjct: 223 DDDKDEVSEEEEE 235



 Score = 38.9 bits (89), Expect = 0.030
 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 8/63 (12%)

Query: 129 DLSNMEGKTGNTTDDEEEEEVEEEEE----DDDEDSGAEIEDDDEE----GFDDEDEFDD 180
           +L   E +  +   D++++EV EEEE    D DED   E ED++EE    G + + E DD
Sbjct: 209 ELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDD 268

Query: 181 EHD 183
           E D
Sbjct: 269 EED 271



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 29/110 (26%), Positives = 41/110 (37%), Gaps = 18/110 (16%)

Query: 64  DLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQ 123
           D Q +G D  E         D   E+G    L    D +      D K            
Sbjct: 179 DAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKD----------- 227

Query: 124 ALLISDLSNMEGKTG--NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEG 171
                ++S  E + G     DDE+E+E EEEEE    ++     DD+E+G
Sbjct: 228 -----EVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEEDG 272


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 30/81 (37%), Positives = 50/81 (61%), Gaps = 3/81 (3%)

Query: 134 EGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIE--DDDEEGFDDEDEFD-DEHDDDLDTED 190
           E + G    D E E+ EEEE D++ED   ++E  DD +E  ++E+EF  D+ +DD D ++
Sbjct: 190 EDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDE 249

Query: 191 NELEELEERAEARKKTTEKQQ 211
           +E EE   + E RK+ T+ ++
Sbjct: 250 DEEEEESGKGENRKRETDDEE 270



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 23/73 (31%), Positives = 43/73 (58%), Gaps = 7/73 (9%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDD----DLDTEDNELEELEE 198
           D  + E +E  + D +  G + E++DEEG   EDE D E++D    +LD E++E E++E 
Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDEEG---EDEKDXENEDGEEEELDEEEDEDEDVEG 222

Query: 199 RAEARKKTTEKQQ 211
             +  + + E+++
Sbjct: 223 DDDKDEVSEEEEE 235



 Score = 38.9 bits (89), Expect = 0.030
 Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 8/63 (12%)

Query: 129 DLSNMEGKTGNTTDDEEEEEVEEEEE----DDDEDSGAEIEDDDEE----GFDDEDEFDD 180
           +L   E +  +   D++++EV EEEE    D DED   E ED++EE    G + + E DD
Sbjct: 209 ELDEEEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDD 268

Query: 181 EHD 183
           E D
Sbjct: 269 EED 271



 Score = 34.7 bits (78), Expect = 0.57
 Identities = 29/110 (26%), Positives = 41/110 (37%), Gaps = 18/110 (16%)

Query: 64  DLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQ 123
           D Q +G D  E         D   E+G    L    D +      D K            
Sbjct: 179 DAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKD----------- 227

Query: 124 ALLISDLSNMEGKTG--NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEG 171
                ++S  E + G     DDE+E+E EEEEE    ++     DD+E+G
Sbjct: 228 -----EVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEEDG 272


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 33/123 (26%), Positives = 64/123 (52%), Gaps = 8/123 (6%)

Query: 70  QDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNG-------L 122
           +DLG+ ++    G     +E   G+ S  G+  +   P D ++   +  +         L
Sbjct: 182 EDLGQAAKPGP-GIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL 240

Query: 123 QALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEH 182
           +     + S  +G   +  +DEEEEE EEEEE+D+E+   E E+++EE  ++E+E ++E 
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300

Query: 183 DDD 185
           +++
Sbjct: 301 EEE 303


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 8/85 (9%)

Query: 132 NMEGKTGNTTDDEEEEEVEEEEEDDDED-SGAEIEDDDEE---GFDDEDEFDDEHDDDLD 187
           N  G      ++EEEEE E+E+ED+DED +G+E+ + +EE    +  ++E  DE DDD  
Sbjct: 176 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 235

Query: 188 TEDNELEELEE----RAEARKKTTE 208
            E+ E EE EE    R E RK+  E
Sbjct: 236 VEEGEEEEEEEEGGLRGEKRKRDAE 260



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 24/66 (36%), Positives = 42/66 (63%), Gaps = 7/66 (10%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDE------EGFDDEDEFDDEHDDDLDTEDNEL-EE 195
           D+E+ E  + EE+DDED   + E+++E      EG+++E+E ++E D+D D +++E   E
Sbjct: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208

Query: 196 LEERAE 201
           L E  E
Sbjct: 209 LGEGEE 214



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 24/77 (31%), Positives = 46/77 (59%), Gaps = 1/77 (1%)

Query: 122 LQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDE 181
           LQ +   D  + E      +++E++E+ +E++E+++E+     E  +EE  ++E+E +DE
Sbjct: 139 LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDE 198

Query: 182 HDDDLDTEDNELEELEE 198
            D+D D   +EL E EE
Sbjct: 199 -DEDEDEAGSELGEGEE 214



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)

Query: 146 EEEVEEEEEDDD-EDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTED 190
           +EE+++EE+DDD  + G E E+++E G   E    D  DD  + +D
Sbjct: 223 KEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 22/94 (23%)

Query: 84  DESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDD 143
           DE E+E   GS    G+ E+                 GL  L+  ++ + E       DD
Sbjct: 197 DEDEDEDEAGSELGEGEEEV-----------------GLSYLMKEEIQDEEDD-----DD 234

Query: 144 EEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDE 177
             EE  EEEEE++    G + + D E+  ++ED+
Sbjct: 235 YVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 8/85 (9%)

Query: 132 NMEGKTGNTTDDEEEEEVEEEEEDDDED-SGAEIEDDDEE---GFDDEDEFDDEHDDDLD 187
           N  G      ++EEEEE E+E+ED+DED +G+E+ + +EE    +  ++E  DE DDD  
Sbjct: 135 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 194

Query: 188 TEDNELEELEE----RAEARKKTTE 208
            E+ E EE EE    R E RK+  E
Sbjct: 195 VEEGEEEEEEEEGGLRGEKRKRDAE 219



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 24/66 (36%), Positives = 42/66 (63%), Gaps = 7/66 (10%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDE------EGFDDEDEFDDEHDDDLDTEDNEL-EE 195
           D+E+ E  + EE+DDED   + E+++E      EG+++E+E ++E D+D D +++E   E
Sbjct: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167

Query: 196 LEERAE 201
           L E  E
Sbjct: 168 LGEGEE 173



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 24/77 (31%), Positives = 46/77 (59%), Gaps = 1/77 (1%)

Query: 122 LQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDE 181
           LQ +   D  + E      +++E++E+ +E++E+++E+     E  +EE  ++E+E +DE
Sbjct: 98  LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDE 157

Query: 182 HDDDLDTEDNELEELEE 198
            D+D D   +EL E EE
Sbjct: 158 -DEDEDEAGSELGEGEE 173



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)

Query: 146 EEEVEEEEEDDD-EDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTED 190
           +EE+++EE+DDD  + G E E+++E G   E    D  DD  + +D
Sbjct: 182 KEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 22/94 (23%)

Query: 84  DESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDD 143
           DE E+E   GS    G+ E+                 GL  L+  ++ + E       DD
Sbjct: 156 DEDEDEDEAGSELGEGEEEV-----------------GLSYLMKEEIQDEEDD-----DD 193

Query: 144 EEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDE 177
             EE  EEEEE++    G + + D E+  ++ED+
Sbjct: 194 YVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 8/85 (9%)

Query: 132 NMEGKTGNTTDDEEEEEVEEEEEDDDED-SGAEIEDDDEE---GFDDEDEFDDEHDDDLD 187
           N  G      ++EEEEE E+E+ED+DED +G+E+ + +EE    +  ++E  DE DDD  
Sbjct: 128 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 187

Query: 188 TEDNELEELEE----RAEARKKTTE 208
            E+ E EE EE    R E RK+  E
Sbjct: 188 VEEGEEEEEEEEGGLRGEKRKRDAE 212



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 24/66 (36%), Positives = 42/66 (63%), Gaps = 7/66 (10%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDE------EGFDDEDEFDDEHDDDLDTEDNEL-EE 195
           D+E+ E  + EE+DDED   + E+++E      EG+++E+E ++E D+D D +++E   E
Sbjct: 101 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 160

Query: 196 LEERAE 201
           L E  E
Sbjct: 161 LGEGEE 166



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 24/77 (31%), Positives = 46/77 (59%), Gaps = 1/77 (1%)

Query: 122 LQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDE 181
           LQ +   D  + E      +++E++E+ +E++E+++E+     E  +EE  ++E+E +DE
Sbjct: 91  LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDE 150

Query: 182 HDDDLDTEDNELEELEE 198
            D+D D   +EL E EE
Sbjct: 151 -DEDEDEAGSELGEGEE 166



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 17/46 (36%), Positives = 28/46 (60%), Gaps = 1/46 (2%)

Query: 146 EEEVEEEEEDDD-EDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTED 190
           +EE+++EE+DDD  + G E E+++E G   E    D  DD  + +D
Sbjct: 175 KEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 22/94 (23%)

Query: 84  DESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDD 143
           DE E+E   GS    G+ E+                 GL  L+  ++ + E       DD
Sbjct: 149 DEDEDEDEAGSELGEGEEEV-----------------GLSYLMKEEIQDEEDD-----DD 186

Query: 144 EEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDE 177
             EE  EEEEE++    G + + D E+  ++ED+
Sbjct: 187 YVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 39/91 (42%), Positives = 47/91 (51%), Gaps = 20/91 (21%)

Query: 135 GKTGNTTD-DEEEEEVEEEEEDDDEDSGAEIEDDDE---------------EGFDDEDEF 178
           GK     D DEEE++  EE+E+DDED   E ED+DE               E  DDED+ 
Sbjct: 137 GKNAKKEDSDEEEDDDSEEDEEDDED---EDEDEDEIEPAAMKAAAAAPASEDEDDEDDE 193

Query: 179 DDEHDDDLDTEDNELEELEERAEARKKTTEK 209
           DDE DDD D ED+  EE  E   A+ K   K
Sbjct: 194 DDEDDDD-DEEDDSEEEAMETTPAKGKKAAK 223



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 49/193 (25%), Positives = 80/193 (41%), Gaps = 50/193 (25%)

Query: 47  ILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKS 106
           ++A PG+  A        +   G   G+N++      ++S+EE    S  +  D E    
Sbjct: 118 LVATPGKKGAA-------IPAKGAKNGKNAK-----KEDSDEEEDDDSEEDEEDDE--DE 163

Query: 107 PSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEE-------------- 152
             D  +     ++    A    D  + + +     DD+EE++ EEE              
Sbjct: 164 DEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAK 223

Query: 153 --------------EEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198
                         EE+DDED     EDDD+   D++DE DD+ DD+ + E+ E E ++E
Sbjct: 224 VVPVKAKNVAEDEDEEEDDED-----EDDDD---DEDDEDDDDEDDEEEEEEEEEEPVKE 275

Query: 199 RAEARKKTTEKQQ 211
               RKK   KQ+
Sbjct: 276 APGKRKKEMAKQK 288


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 30/85 (35%), Positives = 49/85 (57%), Gaps = 1/85 (1%)

Query: 128 SDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDE-HDDDL 186
           S +   +   G    DE+EE+  EE  +D+++ G E E+D+E   ++E+E ++E  DDD 
Sbjct: 85  SSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDE 144

Query: 187 DTEDNELEELEERAEARKKTTEKQQ 211
           D ED E EE EE  E  ++  E+ +
Sbjct: 145 DGEDVEDEEEEEEEEEEEEEEEENE 169



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 24/44 (54%), Positives = 37/44 (84%), Gaps = 1/44 (2%)

Query: 142 DDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDD 185
           D EEEEE+EEE+EDDDED G ++ED++EE  ++E+E ++E ++D
Sbjct: 128 DREEEEEIEEEDEDDDED-GEDVEDEEEEEEEEEEEEEEEENED 170



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 8/84 (9%)

Query: 129 DLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDT 188
           D+   E   G    ++ +E  +E+EED++ D       ++EE  ++EDE DDE  D  D 
Sbjct: 98  DMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDR------EEEEEIEEEDEDDDE--DGEDV 149

Query: 189 EDNELEELEERAEARKKTTEKQQL 212
           ED E EE EE  E  ++  E  Q+
Sbjct: 150 EDEEEEEEEEEEEEEEEENEDHQM 173



 Score = 38.5 bits (88), Expect = 0.039
 Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 8/72 (11%)

Query: 142 DDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDN-------ELE 194
           D+EEEEE EEEEE+++E+   ++   +     D ++ DD ++D+ D  D         L 
Sbjct: 151 DEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEK-DDNNNDEYDNYDELVAKSLLNLG 209

Query: 195 ELEERAEARKKT 206
           ++ E A  R +T
Sbjct: 210 KIAEDAAYRART 221



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 1/58 (1%)

Query: 145 EEEEVEEEEEDDDEDSGAEIEDDDEEGF-DDEDEFDDEHDDDLDTEDNELEELEERAE 201
           +   V+E ++ D  +   E E+D+ E + +D DE  DE ++D + +  E EE+EE  E
Sbjct: 83  DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE 140



 Score = 35.0 bits (79), Expect = 0.44
 Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 4/59 (6%)

Query: 142 DDEE----EEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEEL 196
           DDE+    E+E EEEEE+++E+   E ED      +     D E DD+ + E +  +EL
Sbjct: 142 DDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDEL 200


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 32/59 (54%), Positives = 37/59 (62%), Gaps = 8/59 (13%)

Query: 142  DDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERA 200
            D+EEE E+ EEE +DDED     EDDDE   DD+DE DDE DDD D   +  E L E A
Sbjct: 1677 DEEEELELPEEEAEDDED-----EDDDE---DDDDEDDDEDDDDEDLRTDSEESLPEAA 1727



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 24/49 (48%), Positives = 30/49 (61%), Gaps = 1/49 (2%)

Query: 154  EDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDL-DTEDNELEELEERAE 201
            E   ED   E+E  +EE  DDEDE DDE DDD  D ED++ E+L   +E
Sbjct: 1672 ESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSE 1720



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 13/46 (28%), Positives = 27/46 (58%), Gaps = 3/46 (6%)

Query: 129  DLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDD 174
            +L   E +     DD+E+++ E+++EDDD++   ++  D EE   +
Sbjct: 1683 ELPEEEAEDDEDEDDDEDDDDEDDDEDDDDE---DLRTDSEESLPE 1725



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 14/48 (29%), Positives = 30/48 (62%)

Query: 165  EDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQQL 212
            ED++EE    E+E +D+ D+D D +D++ ++ E+  +   +T  ++ L
Sbjct: 1676 EDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESL 1723


>gi|170763500 SET translocation (myeloid leukemia-associated)
           isoform 1 [Homo sapiens]
          Length = 290

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 29/63 (46%), Positives = 41/63 (65%), Gaps = 1/63 (1%)

Query: 120 NGLQALLISDLSNMEGKTGNTTDDEEEEE-VEEEEEDDDEDSGAEIEDDDEEGFDDEDEF 178
           N LQ  L+ D+ + EG+     DD+EEEE +E+ +E+ DED G E EDDDE    +EDE 
Sbjct: 228 NPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEG 287

Query: 179 DDE 181
           +D+
Sbjct: 288 EDD 290



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 23/53 (43%), Positives = 37/53 (69%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195
           D ++EE E EE+DDD++    +ED DEEG +DE E D++ D+  + E++E E+
Sbjct: 237 DMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEGED 289



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 20/51 (39%), Positives = 35/51 (68%), Gaps = 3/51 (5%)

Query: 148 EVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198
           ++++EE + +ED   + +D++EEG +D DE  DE + + D +D+E EE EE
Sbjct: 237 DMDDEEGEGEED---DDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEE 284



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 3/48 (6%)

Query: 167 DDEEGFDDEDEFDDEHDD---DLDTEDNELEELEERAEARKKTTEKQQ 211
           DDEEG  +ED+ DDE ++   D+D E +E E  E+  +   +  E+ +
Sbjct: 239 DDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDE 286


>gi|170763498 SET translocation (myeloid leukemia-associated)
           isoform 2 [Homo sapiens]
          Length = 277

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 29/63 (46%), Positives = 41/63 (65%), Gaps = 1/63 (1%)

Query: 120 NGLQALLISDLSNMEGKTGNTTDDEEEEE-VEEEEEDDDEDSGAEIEDDDEEGFDDEDEF 178
           N LQ  L+ D+ + EG+     DD+EEEE +E+ +E+ DED G E EDDDE    +EDE 
Sbjct: 215 NPLQYYLVPDMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEG 274

Query: 179 DDE 181
           +D+
Sbjct: 275 EDD 277



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 23/53 (43%), Positives = 37/53 (69%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195
           D ++EE E EE+DDD++    +ED DEEG +DE E D++ D+  + E++E E+
Sbjct: 224 DMDDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDEGED 276



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 20/51 (39%), Positives = 35/51 (68%), Gaps = 3/51 (5%)

Query: 148 EVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198
           ++++EE + +ED   + +D++EEG +D DE  DE + + D +D+E EE EE
Sbjct: 224 DMDDEEGEGEED---DDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEE 271



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 3/48 (6%)

Query: 167 DDEEGFDDEDEFDDEHDD---DLDTEDNELEELEERAEARKKTTEKQQ 211
           DDEEG  +ED+ DDE ++   D+D E +E E  E+  +   +  E+ +
Sbjct: 226 DDEEGEGEEDDDDDEEEEGLEDIDEEGDEDEGEEDEDDDEGEEGEEDE 273


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 3/72 (4%)

Query: 136 KTGNTTDDEEEEEVE--EEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNEL 193
           +T   T D +E  VE  EE ED + +   E EDD+++  DD+D+ DD+ +DD D ED E 
Sbjct: 229 RTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGE- 287

Query: 194 EELEERAEARKK 205
           EE ++R   R++
Sbjct: 288 EENQKRYYLRQR 299



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 23/72 (31%), Positives = 43/72 (59%), Gaps = 2/72 (2%)

Query: 128 SDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLD 187
           +D    + + G+    EE E+ E E++ +DED   + +DDD++  DD+D+ DDE ++D +
Sbjct: 230 TDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDD--DDDDDEDDEDEEDGE 287

Query: 188 TEDNELEELEER 199
            E+ +   L +R
Sbjct: 288 EENQKRYYLRQR 299



 Score = 38.5 bits (88), Expect = 0.039
 Identities = 17/65 (26%), Positives = 36/65 (55%)

Query: 147 EEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKT 206
           +  +EE  D+ E S    E+ +++  +D+ E +D+ DDD D +D++ ++ E+  +     
Sbjct: 228 QRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGE 287

Query: 207 TEKQQ 211
            E Q+
Sbjct: 288 EENQK 292



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 18/83 (21%), Positives = 44/83 (53%)

Query: 141 TDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERA 200
           T  ++++    +EE  D   G+    ++ E  + ED+ +DE D+D D +D++ ++ ++  
Sbjct: 220 TRGKQKDIQRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDED 279

Query: 201 EARKKTTEKQQLQSLFLLWSKLT 223
           +  ++  E++  +  +L   K T
Sbjct: 280 DEDEEDGEEENQKRYYLRQRKAT 302


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 32/76 (42%), Positives = 42/76 (55%), Gaps = 14/76 (18%)

Query: 131 SNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGA------------EIEDDDEEGFDDEDEF 178
           S  E +  +  D+++E+E EEEE+D++ DS              E ED DE   DDEDE 
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 179 DDEHDDDLDTEDNELE 194
           DDE DD  + EDNE E
Sbjct: 696 DDEDDD--EDEDNESE 709



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 30/98 (30%), Positives = 51/98 (52%), Gaps = 11/98 (11%)

Query: 128 SDLSNMEGKTGNTTDDEEEE--EVEEEEEDDDE---------DSGAEIEDDDEEGFDDED 176
           S  + ++ K+ +  DDEE+E  E E+EEE+DDE         DS     +D+ E  D+ +
Sbjct: 629 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 688

Query: 177 EFDDEHDDDLDTEDNELEELEERAEARKKTTEKQQLQS 214
           E D++ DDD D +++E  E E  + +   + +     S
Sbjct: 689 EDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 14/53 (26%), Positives = 29/53 (54%)

Query: 139 NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDN 191
           ++++DE E+  E EE+D+DED   + ++D++   +          D  D++ N
Sbjct: 675 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 29/147 (19%), Positives = 64/147 (43%), Gaps = 7/147 (4%)

Query: 66  QPNGQDLGENSRVARLGADESEEE-GRRGSLSNAGDPEIVKSPSDPKQYRY-IKLQNGLQ 123
           Q   Q+L  N  +  L   E   E G R    +    E  K  ++ +Q +Y + L   ++
Sbjct: 539 QKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVK 598

Query: 124 ALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHD 183
           +L   D +  +    N     + + + +    + + S   ++   E   DDE++ DDE +
Sbjct: 599 SLSPQDRAAYKEYISN-----KRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDE 653

Query: 184 DDLDTEDNELEELEERAEARKKTTEKQ 210
           D+ + +D   +  E+  ++ + ++E +
Sbjct: 654 DEEEEDDENGDSSEDGGDSSESSSEDE 680


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 32/76 (42%), Positives = 42/76 (55%), Gaps = 14/76 (18%)

Query: 131 SNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGA------------EIEDDDEEGFDDEDEF 178
           S  E +  +  D+++E+E EEEE+D++ DS              E ED DE   DDEDE 
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 179 DDEHDDDLDTEDNELE 194
           DDE DD  + EDNE E
Sbjct: 696 DDEDDD--EDEDNESE 709



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 30/98 (30%), Positives = 51/98 (52%), Gaps = 11/98 (11%)

Query: 128 SDLSNMEGKTGNTTDDEEEE--EVEEEEEDDDE---------DSGAEIEDDDEEGFDDED 176
           S  + ++ K+ +  DDEE+E  E E+EEE+DDE         DS     +D+ E  D+ +
Sbjct: 629 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 688

Query: 177 EFDDEHDDDLDTEDNELEELEERAEARKKTTEKQQLQS 214
           E D++ DDD D +++E  E E  + +   + +     S
Sbjct: 689 EDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 14/53 (26%), Positives = 29/53 (54%)

Query: 139 NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDN 191
           ++++DE E+  E EE+D+DED   + ++D++   +          D  D++ N
Sbjct: 675 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 29/147 (19%), Positives = 64/147 (43%), Gaps = 7/147 (4%)

Query: 66  QPNGQDLGENSRVARLGADESEEE-GRRGSLSNAGDPEIVKSPSDPKQYRY-IKLQNGLQ 123
           Q   Q+L  N  +  L   E   E G R    +    E  K  ++ +Q +Y + L   ++
Sbjct: 539 QKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVK 598

Query: 124 ALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHD 183
           +L   D +  +    N     + + + +    + + S   ++   E   DDE++ DDE +
Sbjct: 599 SLSPQDRAAYKEYISN-----KRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDE 653

Query: 184 DDLDTEDNELEELEERAEARKKTTEKQ 210
           D+ + +D   +  E+  ++ + ++E +
Sbjct: 654 DEEEEDDENGDSSEDGGDSSESSSEDE 680


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 32/76 (42%), Positives = 42/76 (55%), Gaps = 14/76 (18%)

Query: 131 SNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGA------------EIEDDDEEGFDDEDEF 178
           S  E +  +  D+++E+E EEEE+D++ DS              E ED DE   DDEDE 
Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 732

Query: 179 DDEHDDDLDTEDNELE 194
           DDE DD  + EDNE E
Sbjct: 733 DDEDDD--EDEDNESE 746



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 30/98 (30%), Positives = 51/98 (52%), Gaps = 11/98 (11%)

Query: 128 SDLSNMEGKTGNTTDDEEEE--EVEEEEEDDDE---------DSGAEIEDDDEEGFDDED 176
           S  + ++ K+ +  DDEE+E  E E+EEE+DDE         DS     +D+ E  D+ +
Sbjct: 666 SSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE 725

Query: 177 EFDDEHDDDLDTEDNELEELEERAEARKKTTEKQQLQS 214
           E D++ DDD D +++E  E E  + +   + +     S
Sbjct: 726 EDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 763



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 14/53 (26%), Positives = 29/53 (54%)

Query: 139 NTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDN 191
           ++++DE E+  E EE+D+DED   + ++D++   +          D  D++ N
Sbjct: 712 SSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 29/147 (19%), Positives = 64/147 (43%), Gaps = 7/147 (4%)

Query: 66  QPNGQDLGENSRVARLGADESEEE-GRRGSLSNAGDPEIVKSPSDPKQYRY-IKLQNGLQ 123
           Q   Q+L  N  +  L   E   E G R    +    E  K  ++ +Q +Y + L   ++
Sbjct: 576 QKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVK 635

Query: 124 ALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHD 183
           +L   D +  +    N     + + + +    + + S   ++   E   DDE++ DDE +
Sbjct: 636 SLSPQDRAAYKEYISN-----KRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDE 690

Query: 184 DDLDTEDNELEELEERAEARKKTTEKQ 210
           D+ + +D   +  E+  ++ + ++E +
Sbjct: 691 DEEEEDDENGDSSEDGGDSSESSSEDE 717


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 34/89 (38%), Positives = 53/89 (59%), Gaps = 11/89 (12%)

Query: 131 SNMEGKTGNTTDDEEEEEVEEEEED-------DDEDSGAEIEDDDEEGFDDEDEFDDEHD 183
           S+ EG      D+EE+E+ EE +ED       +DED   E E++D  G ++EDE +  +D
Sbjct: 158 SDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDE-EGYND 216

Query: 184 DDLDTEDNELEEL--EERAEARKKTTEKQ 210
            ++D E++E EEL  EER + RK+  E +
Sbjct: 217 GEVDDEEDE-EELGEEERGQKRKREPEDE 244



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 4/62 (6%)

Query: 151 EEEEDDDEDSGAEIED-DDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEK 209
           +++E  D D+   +E  DDEE  +DE+E+D   +D    ED E E+ EE  E    + E+
Sbjct: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYD---EDAQVVEDEEDEDEEEEGEEEDVSGEE 207

Query: 210 QQ 211
           ++
Sbjct: 208 EE 209



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 9/53 (16%)

Query: 142 DDEEEEEVEEEEEDDDE---DSGAEIEDDDEEGFDDE------DEFDDEHDDD 185
           ++ EEE+V  EEE+D+E   D   + E+D+EE  ++E       E +DE +DD
Sbjct: 196 EEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248


>gi|42740903 MTERF domain containing 2 [Homo sapiens]
          Length = 381

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 25/66 (37%), Positives = 44/66 (66%), Gaps = 4/66 (6%)

Query: 130 LSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTE 189
           L+  E ++ ++T D++   ++E+E+DDDE    E  D+D+   DD+DE DDE +D+ + E
Sbjct: 320 LAREEEESESSTSDDKRASLDEDEDDDDE----EDNDEDDNDEDDDDEDDDEAEDNDEDE 375

Query: 190 DNELEE 195
           D++ EE
Sbjct: 376 DDDEEE 381



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 26/59 (44%), Positives = 36/59 (61%), Gaps = 2/59 (3%)

Query: 145 EEEEVEEEEEDDDEDSGAEIEDDDEEGFDDED--EFDDEHDDDLDTEDNELEELEERAE 201
           EEEE E    DD   S  E EDDD+E  +DED  + DD+ +DD + EDN+ +E ++  E
Sbjct: 323 EEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE 381



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 21/56 (37%), Positives = 37/56 (66%), Gaps = 1/56 (1%)

Query: 128 SDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHD 183
           S+ S  + K  +  +DE++++ E+ +EDD+++   + EDDDE   +DEDE DDE +
Sbjct: 327 SESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDD-EDDDEAEDNDEDEDDDEEE 381



 Score = 33.9 bits (76), Expect = 0.97
 Identities = 15/58 (25%), Positives = 32/58 (55%)

Query: 141 TDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198
           T  EE +  ++    ++E+S +   DD     D++++ DDE D+D D  D + ++ ++
Sbjct: 308 TSVEEFQVFKKLLAREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDD 365



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 6/52 (11%)

Query: 151 EEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEA 202
           EEEE +   S      DD+    DEDE DD+ +D+ + +++E ++ E+  EA
Sbjct: 323 EEEESESSTS------DDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEA 368


>gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 302

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 29/65 (44%), Positives = 39/65 (60%), Gaps = 3/65 (4%)

Query: 120 NGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEED---DDEDSGAEIEDDDEEGFDDED 176
           N LQ  L+ D+ + EG   +  DD++ +E EEE ED    DED G E EDDDE    +ED
Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEED 297

Query: 177 EFDDE 181
           E +D+
Sbjct: 298 EGEDD 302



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 20/48 (41%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 156 DDEDSGAEIEDDDEEGFDDEDEFDD--EHDDDLDTEDNELEELEERAE 201
           DDE+ G + +DDD++G + E+E +D  E D+D   ED + +E EE  E
Sbjct: 249 DDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEE 296



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 18/51 (35%), Positives = 33/51 (64%), Gaps = 1/51 (1%)

Query: 148 EVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198
           ++++EE  +D+D   +  D+ EE  +D DE D++  ++ D +D+E EE EE
Sbjct: 247 DMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEE-DEDDDEGEEGEE 296



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 5/51 (9%)

Query: 150 EEEEEDDDE-----DSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195
           EE  EDDD+     D G E  +D +EG +DE E D++ D+  + E++E E+
Sbjct: 251 EEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEEDEGED 301



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 8/63 (12%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEI----EDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198
           D   +E+EE  +DD   +  +     + DDEEG +D    DD+ DDD D  + ELE+++E
Sbjct: 221 DAGADELEEVIKDDIWPNPLQYYLVPDMDDEEGGED----DDDDDDDGDEGEEELEDIDE 276

Query: 199 RAE 201
             E
Sbjct: 277 GDE 279


>gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 302

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 29/65 (44%), Positives = 39/65 (60%), Gaps = 3/65 (4%)

Query: 120 NGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEED---DDEDSGAEIEDDDEEGFDDED 176
           N LQ  L+ D+ + EG   +  DD++ +E EEE ED    DED G E EDDDE    +ED
Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEED 297

Query: 177 EFDDE 181
           E +D+
Sbjct: 298 EGEDD 302



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 20/48 (41%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 156 DDEDSGAEIEDDDEEGFDDEDEFDD--EHDDDLDTEDNELEELEERAE 201
           DDE+ G + +DDD++G + E+E +D  E D+D   ED + +E EE  E
Sbjct: 249 DDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEE 296



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 18/51 (35%), Positives = 33/51 (64%), Gaps = 1/51 (1%)

Query: 148 EVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198
           ++++EE  +D+D   +  D+ EE  +D DE D++  ++ D +D+E EE EE
Sbjct: 247 DMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEE-DEDDDEGEEGEE 296



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 5/51 (9%)

Query: 150 EEEEEDDDE-----DSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195
           EE  EDDD+     D G E  +D +EG +DE E D++ D+  + E++E E+
Sbjct: 251 EEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEEDEGED 301



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 8/63 (12%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEI----EDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198
           D   +E+EE  +DD   +  +     + DDEEG +D    DD+ DDD D  + ELE+++E
Sbjct: 221 DAGADELEEVIKDDIWPNPLQYYLVPDMDDEEGGED----DDDDDDDGDEGEEELEDIDE 276

Query: 199 RAE 201
             E
Sbjct: 277 GDE 279


>gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens]
          Length = 302

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 29/65 (44%), Positives = 39/65 (60%), Gaps = 3/65 (4%)

Query: 120 NGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEED---DDEDSGAEIEDDDEEGFDDED 176
           N LQ  L+ D+ + EG   +  DD++ +E EEE ED    DED G E EDDDE    +ED
Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEED 297

Query: 177 EFDDE 181
           E +D+
Sbjct: 298 EGEDD 302



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 20/48 (41%), Positives = 31/48 (64%), Gaps = 2/48 (4%)

Query: 156 DDEDSGAEIEDDDEEGFDDEDEFDD--EHDDDLDTEDNELEELEERAE 201
           DDE+ G + +DDD++G + E+E +D  E D+D   ED + +E EE  E
Sbjct: 249 DDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEE 296



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 18/51 (35%), Positives = 33/51 (64%), Gaps = 1/51 (1%)

Query: 148 EVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198
           ++++EE  +D+D   +  D+ EE  +D DE D++  ++ D +D+E EE EE
Sbjct: 247 DMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEE-DEDDDEGEEGEE 296



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 5/51 (9%)

Query: 150 EEEEEDDDE-----DSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195
           EE  EDDD+     D G E  +D +EG +DE E D++ D+  + E++E E+
Sbjct: 251 EEGGEDDDDDDDDGDEGEEELEDIDEGDEDEGEEDEDDDEGEEGEEDEGED 301



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 8/63 (12%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEI----EDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEE 198
           D   +E+EE  +DD   +  +     + DDEEG +D    DD+ DDD D  + ELE+++E
Sbjct: 221 DAGADELEEVIKDDIWPNPLQYYLVPDMDDEEGGED----DDDDDDDGDEGEEELEDIDE 276

Query: 199 RAE 201
             E
Sbjct: 277 GDE 279


>gi|157743245 WD repeat domain 43 [Homo sapiens]
          Length = 677

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 31/102 (30%), Positives = 56/102 (54%), Gaps = 2/102 (1%)

Query: 111 KQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEE 170
           K ++ +   +G   LLI+ ++  E   G T+  ++ + V EEE  ++E      + D E+
Sbjct: 560 KTFQKLSHLHGKLILLITQVTASEKTKGATSPGQKAKLVYEEESSEEESDDEIADKDSED 619

Query: 171 GFD-DEDEFDDEHDDDLDTEDNELE-ELEERAEARKKTTEKQ 210
            +D DE+E + E D+D++ ED + E + EE  E R   +EK+
Sbjct: 620 NWDEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKE 661



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 22/56 (39%), Positives = 32/56 (57%), Gaps = 3/56 (5%)

Query: 143 DEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEH---DDDLDTEDNELEE 195
           DE+EEE E E+++D E+   + E  DEE  +D D   ++    D DLD E+   EE
Sbjct: 622 DEDEEESESEKDEDVEEEDEDAEGKDEENGEDRDTASEKELNGDSDLDPENESEEE 677


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 56/221 (25%), Positives = 93/221 (42%), Gaps = 59/221 (26%)

Query: 25   AALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTC--SCPDLQPNGQDLGE--NSRVAR 80
            AAL  +ET  R  +  ++  F   +   +NK++     +  D   N QD GE   + V  
Sbjct: 2245 AALKPLETLSRIVNQPSSL-FGSKSASSKNKSEQDAQGASQDSSSNQQDPGEPGEAEVQE 2303

Query: 81   LGADESEEEGRRGSLSN----------AGDPEIVKSPSDPKQYRYIKLQNGLQALLISDL 130
               D ++ E   G + +          AG PE++ S         ++++N L+ L I +L
Sbjct: 2304 EDHDVTQTEVADGDIMDGEAETDSVVIAGQPEVLSSQE-------MQVENELEDL-IDEL 2355

Query: 131  SNMEGKTGNTT-------DDEEEEEV-----------------------------EEEEE 154
               +G +GN+T       +DE +E+V                             +EEE 
Sbjct: 2356 LERDGGSGNSTIIVSRSGEDESQEDVLMDEAPSNLSQASTLQANREDSMNILDPEDEEEH 2415

Query: 155  DDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195
              +EDS    ED+D+   ++E+E +DE DD  D E  E +E
Sbjct: 2416 TQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDE 2456



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 17/118 (14%)

Query: 78   VARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKT 137
            V+R G DES+E           D  + ++PS+  Q       + LQA     ++ ++ + 
Sbjct: 2369 VSRSGEDESQE-----------DVLMDEAPSNLSQ------ASTLQANREDSMNILDPED 2411

Query: 138  GNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195
                  EE+     E+EDD +D   E E+D+E+  +D++  + + DDD D  + EL+E
Sbjct: 2412 EEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDE 2469


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 33/130 (25%), Positives = 67/130 (51%), Gaps = 6/130 (4%)

Query: 89  EGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEE 148
           +G+  ++SN  +P   +  S P +   ++   G      SD+ + +    +  D+EE++E
Sbjct: 562 QGKEKAVSNNVNPVKTQHHSHPAK-SLVEQFRGTD----SDIPSSKDSEDSNEDEEEDDE 616

Query: 149 VEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELE-ELEERAEARKKTT 207
            E+EE+D+D++S     + D     D +  ++E DDD D ++++ + E E+ +    KTT
Sbjct: 617 EEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTT 676

Query: 208 EKQQLQSLFL 217
              +  S+ L
Sbjct: 677 SSVKSPSMSL 686



 Score = 37.7 bits (86), Expect = 0.067
 Identities = 20/86 (23%), Positives = 41/86 (47%), Gaps = 4/86 (4%)

Query: 133 MEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGF---DDEDEFDDEHDDDLDTE 189
           ++ +     D +  ++  E   + D DSG    D   EG    D +D  +DE ++D   E
Sbjct: 222 LDARVDKIKDKKPRKKAMESSSNSDSDSGTS-SDTSSEGISSSDSDDLEEDEEEEDQSIE 280

Query: 190 DNELEELEERAEARKKTTEKQQLQSL 215
           ++E ++ +  +EA+ K+  +  L  +
Sbjct: 281 ESEDDDSDSESEAQHKSNNQVLLHGI 306



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 35/168 (20%), Positives = 64/168 (38%), Gaps = 9/168 (5%)

Query: 53  RNKAKSTCSCPDLQPNGQDLGENS------RVARLGADESEEEGRRGSLSNAGDPEIV-- 104
           R   KS  + P+   NG   G N+        + L    S   G+  S S+ G       
Sbjct: 155 RTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQ 214

Query: 105 -KSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAE 163
            +S + P   R  K+++        + S+       T+ D   E +   + DD E+   E
Sbjct: 215 EQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEE 274

Query: 164 IEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQQ 211
            +   EE  DD+ + + E     + +       + +A+ +K T + Q+
Sbjct: 275 EDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQE 322



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 5/68 (7%)

Query: 153  EEDDDEDSGAEIEDDDEEGFDDED----EFDDEHDDDLDTEDNELEELEERAEARKKTTE 208
            ++DDD+DS  + ++DDE+  D ED    + D   D+D   +   +EELE++ E   K  +
Sbjct: 1300 DDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSK-QQ 1358

Query: 209  KQQLQSLF 216
             Q  + LF
Sbjct: 1359 SQYRRKLF 1366


>gi|18093112 ABT1-associated protein [Homo sapiens]
          Length = 851

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 39/129 (30%), Positives = 62/129 (48%), Gaps = 12/129 (9%)

Query: 74  ENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNM 133
           E   + +   D S EE +R    ++G  EIVKSP         ++Q+ +Q ++  D    
Sbjct: 168 EKKNIVQHTTDSSLEEKQR--TLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGY 225

Query: 134 EGKTGNTTDDEEEEEVEEE---EEDDDEDSGAEIE-------DDDEEGFDDEDEFDDEHD 183
           E  T     D++  E + E   E   DE+S  EI        DDD    D+E++ D+E D
Sbjct: 226 ENSTDGEMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEED 285

Query: 184 DDLDTEDNE 192
           +D D+ED++
Sbjct: 286 EDEDSEDDD 294



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 16/102 (15%)

Query: 134 EGKTGNTTDDEEEEEVEEE--EEDDDEDSG-------------AEIEDDDEEGFDDEDEF 178
           +G   +  +DE+EEE E+E  E+DD  DSG             +E EDD  + F +E  F
Sbjct: 270 DGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESGF 329

Query: 179 DDEHDDDLDTEDNELEELEERAEARKKTTEKQQLQSLFLLWS 220
           +     +LD +    +E+  R        ++ + + L  L++
Sbjct: 330 EHAW-RELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFN 370



 Score = 31.2 bits (69), Expect = 6.3
 Identities = 21/85 (24%), Positives = 45/85 (52%), Gaps = 8/85 (9%)

Query: 129 DLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDT 188
           +L +M+ +    +  E+EEE+EEE + DD   G  +E+D   G   + + DDE  + +  
Sbjct: 530 ELLDMDFQAYLASSSEDEEEIEEELQGDD---GVNVEED---GKTKKSQKDDE--EQIAK 581

Query: 189 EDNELEELEERAEARKKTTEKQQLQ 213
               L+ ++E+ +  K+   + +++
Sbjct: 582 YRQLLQVIQEKEKKGKENDMEMEIK 606


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 36/124 (29%), Positives = 62/124 (50%), Gaps = 8/124 (6%)

Query: 88  EEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDD-EEE 146
           E  RR S S+    E V S      +     + G         +N E +     +D EE+
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDH-----ETGSSGSSDEQGNNTENEEEGVEEDVEED 212

Query: 147 EEVEEEEEDDDE--DSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARK 204
           EEVEE+ E+D+E  + G E E+++EE  ++E+E ++E++ D   +  E  + + R+EA  
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272

Query: 205 KTTE 208
             +E
Sbjct: 273 SGSE 276



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 28/79 (35%), Positives = 45/79 (56%), Gaps = 12/79 (15%)

Query: 136 KTGNT-TDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELE 194
           +TG++ + DE+    E EEE         +E+D EE  D+E E D E D+++D ED E E
Sbjct: 184 ETGSSGSSDEQGNNTENEEEG--------VEEDVEE--DEEVEEDAEEDEEVD-EDGEEE 232

Query: 195 ELEERAEARKKTTEKQQLQ 213
           E EE  E  ++  E+++ +
Sbjct: 233 EEEEEEEEEEEEEEEEEYE 251



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 20/61 (32%), Positives = 35/61 (57%), Gaps = 6/61 (9%)

Query: 142 DDEEEEEV------EEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEE 195
           D EE+EEV      EEEEE+++E+   E E++ E+   D+ E  +++D   +  D+  E 
Sbjct: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSES 277

Query: 196 L 196
           +
Sbjct: 278 V 278



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 16/74 (21%), Positives = 36/74 (48%)

Query: 142 DDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAE 201
           ++EEEEE EEEEE+++ +     + ++   +D   E  D   + +   D  +        
Sbjct: 234 EEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293

Query: 202 ARKKTTEKQQLQSL 215
           + +K  E+++ + +
Sbjct: 294 SDEKKKERKRARGI 307


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,925,881
Number of Sequences: 37866
Number of extensions: 2347061
Number of successful extensions: 33638
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 498
Number of HSP's successfully gapped in prelim test: 309
Number of HSP's that attempted gapping in prelim test: 14021
Number of HSP's gapped (non-prelim): 8060
length of query: 1219
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1105
effective length of database: 13,930,794
effective search space: 15393527370
effective search space used: 15393527370
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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