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Search of human proteins with 155030242
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|155030242 WD repeat domain 60 [Homo sapiens]
(1066 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|155030242 WD repeat domain 60 [Homo sapiens] 2156 0.0
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 126 1e-28
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 108 4e-23
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 107 8e-23
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 100 6e-21
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 100 1e-20
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 100 1e-20
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 100 1e-20
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 99 3e-20
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 96 2e-19
gi|148746195 trichohyalin [Homo sapiens] 94 5e-19
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 91 6e-18
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 89 2e-17
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 87 8e-17
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 86 2e-16
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 85 3e-16
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 84 7e-16
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 84 9e-16
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 84 9e-16
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 81 5e-15
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 81 5e-15
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 81 5e-15
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 81 5e-15
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 81 6e-15
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 81 6e-15
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 79 2e-14
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 79 2e-14
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 78 5e-14
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 77 9e-14
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 77 1e-13
>gi|155030242 WD repeat domain 60 [Homo sapiens]
Length = 1066
Score = 2156 bits (5586), Expect = 0.0
Identities = 1066/1066 (100%), Positives = 1066/1066 (100%)
Query: 1 MEPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDP 60
MEPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDP
Sbjct: 1 MEPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDP 60
Query: 61 DQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKD 120
DQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKD
Sbjct: 61 DQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKD 120
Query: 121 REKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGD 180
REKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGD
Sbjct: 121 REKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGD 180
Query: 181 EDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKY 240
EDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKY
Sbjct: 181 EDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKY 240
Query: 241 SKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNR 300
SKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNR
Sbjct: 241 SKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNR 300
Query: 301 GASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEET 360
GASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEET
Sbjct: 301 GASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEET 360
Query: 361 DLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQ 420
DLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQ
Sbjct: 361 DLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQ 420
Query: 421 RAINAENERIGELSLKLFQKRGRTEFEKEPRTDTNSSPSRASVCGIFVDFASASHRQKSR 480
RAINAENERIGELSLKLFQKRGRTEFEKEPRTDTNSSPSRASVCGIFVDFASASHRQKSR
Sbjct: 421 RAINAENERIGELSLKLFQKRGRTEFEKEPRTDTNSSPSRASVCGIFVDFASASHRQKSR 480
Query: 481 TQALKQKMRSTKLLRLIDLDFSFTFSLLDLPPVNEYDMYIRNFGKKNTKQAYVQCNEDNV 540
TQALKQKMRSTKLLRLIDLDFSFTFSLLDLPPVNEYDMYIRNFGKKNTKQAYVQCNEDNV
Sbjct: 481 TQALKQKMRSTKLLRLIDLDFSFTFSLLDLPPVNEYDMYIRNFGKKNTKQAYVQCNEDNV 540
Query: 541 ERDIQTEEIETREVWTQHPGESTVVSGGSEQRDTSDAVVMPKIDTPRLCSFLRAACQVMA 600
ERDIQTEEIETREVWTQHPGESTVVSGGSEQRDTSDAVVMPKIDTPRLCSFLRAACQVMA
Sbjct: 541 ERDIQTEEIETREVWTQHPGESTVVSGGSEQRDTSDAVVMPKIDTPRLCSFLRAACQVMA 600
Query: 601 VLLEEDRLAAEPSWNLRAQDRALYFSDSSSQLNTSLPFLQNRKVSSLHTSRVQRQMVVSV 660
VLLEEDRLAAEPSWNLRAQDRALYFSDSSSQLNTSLPFLQNRKVSSLHTSRVQRQMVVSV
Sbjct: 601 VLLEEDRLAAEPSWNLRAQDRALYFSDSSSQLNTSLPFLQNRKVSSLHTSRVQRQMVVSV 660
Query: 661 HDLPEKSFVPLLDSKYVLCVWDIWQPSGPQKVLICESQVTCCCLSPLKAFLLFAGTAHGS 720
HDLPEKSFVPLLDSKYVLCVWDIWQPSGPQKVLICESQVTCCCLSPLKAFLLFAGTAHGS
Sbjct: 661 HDLPEKSFVPLLDSKYVLCVWDIWQPSGPQKVLICESQVTCCCLSPLKAFLLFAGTAHGS 720
Query: 721 VVVWDLREDSRLHYSVTLSDGFWTFRTATFSTDGILTSVNHRSPLQAVEPISTSVHKKQS 780
VVVWDLREDSRLHYSVTLSDGFWTFRTATFSTDGILTSVNHRSPLQAVEPISTSVHKKQS
Sbjct: 721 VVVWDLREDSRLHYSVTLSDGFWTFRTATFSTDGILTSVNHRSPLQAVEPISTSVHKKQS 780
Query: 781 FVLSPFSTQEEMSGLSFHIASLDESGVLNVWVVVELPKADIAGSISDLGLMPGGRVKLVH 840
FVLSPFSTQEEMSGLSFHIASLDESGVLNVWVVVELPKADIAGSISDLGLMPGGRVKLVH
Sbjct: 781 FVLSPFSTQEEMSGLSFHIASLDESGVLNVWVVVELPKADIAGSISDLGLMPGGRVKLVH 840
Query: 841 SALIQLGDSLSHKGNEFWGTTQTLNVKFLPSDPNHFIIGTDMGLISHGTRQDLRVAPKLF 900
SALIQLGDSLSHKGNEFWGTTQTLNVKFLPSDPNHFIIGTDMGLISHGTRQDLRVAPKLF
Sbjct: 841 SALIQLGDSLSHKGNEFWGTTQTLNVKFLPSDPNHFIIGTDMGLISHGTRQDLRVAPKLF 900
Query: 901 KPQQHGIRPVKVNVIDFSPFGEPIFLAGCSDGSIRLHQLSSAFPLLQWDSSTDSHAVTGL 960
KPQQHGIRPVKVNVIDFSPFGEPIFLAGCSDGSIRLHQLSSAFPLLQWDSSTDSHAVTGL
Sbjct: 901 KPQQHGIRPVKVNVIDFSPFGEPIFLAGCSDGSIRLHQLSSAFPLLQWDSSTDSHAVTGL 960
Query: 961 QWSPTRPAVFLVQDDTSNIYIWDLLQSDLGPVAKQQVSPNRLVAMAAVGEPEKAGGSFLA 1020
QWSPTRPAVFLVQDDTSNIYIWDLLQSDLGPVAKQQVSPNRLVAMAAVGEPEKAGGSFLA
Sbjct: 961 QWSPTRPAVFLVQDDTSNIYIWDLLQSDLGPVAKQQVSPNRLVAMAAVGEPEKAGGSFLA 1020
Query: 1021 LVLARASGSIDIQHLKRRWAAPEVDECNRLRLLLQEALWPEGKLHK 1066
LVLARASGSIDIQHLKRRWAAPEVDECNRLRLLLQEALWPEGKLHK
Sbjct: 1021 LVLARASGSIDIQHLKRRWAAPEVDECNRLRLLLQEALWPEGKLHK 1066
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 126 bits (317), Expect = 1e-28
Identities = 118/439 (26%), Positives = 204/439 (46%), Gaps = 48/439 (10%)
Query: 31 KEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQR 90
++ER+ R +K + E E D K R R+ D+ R RDR E +E R ER DR+R
Sbjct: 59 QKERERRREKRQTERETD---RKRERRREKDRH-RKRDRHRERQRDREKER-ERQTDRER 113
Query: 91 ERRRDA-KDREKEKLKEKHREAEKSHSRGKD--REKEKDRRARKEELRQTVAHHNLLGQE 147
+R+R+ ++R+KE+ +E RE E+ R D RE+E+ R A KE RQT Q
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ--RQT 171
Query: 148 TRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRER-RYRERKLQYGDSKDNPLKYWL 206
R+RQ ER K R + R +++++++ D ER R RER+ +
Sbjct: 172 ERNRQ-KEREREKNRQERRERERQREKENKTEDRHSERGRERERERE------------- 217
Query: 207 YKEEGERRHRKPREPDRDNK---HREKSSTREKREKYSKEKSNSFS-DKGEERHKEKRHK 262
+ E ER+ + RE DR K REK + RE+ + E+ ++ +R +++R K
Sbjct: 218 TETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQK 277
Query: 263 EGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHG 322
E D + Q +R ++ + R+RE + RNR +R+ + + R
Sbjct: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ---RETE 334
Query: 323 KDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKE-ETDLENARADAYTASCEDDFEDY 381
+D++ R+ + + + + +++ G E + E+E E + E R A
Sbjct: 335 RDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSA-----------R 383
Query: 382 EDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGELSLKLFQKR 441
E + D D D EK + Q++ ++ +R + E+ER E + +++
Sbjct: 384 EREERERDRDRDRQKERERQTEKDRD---GQRETEKQREREKDRESERGRERGREREKQK 440
Query: 442 GRTEFEKEPRTDTNSSPSR 460
GR E ++E +TD + R
Sbjct: 441 GR-ERDRERQTDRQAGRQR 458
Score = 121 bits (304), Expect = 3e-27
Identities = 102/388 (26%), Positives = 181/388 (46%), Gaps = 43/388 (11%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E +RR K T + D ++ + K +R HRE++ +E E + +E R R +
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDR-HRERQRDREKERERQTDRE-RDRQRE 118
Query: 62 QDARSRDRVAEVHTAKESPRG---ERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRG 118
++ R+R + E T +E RG + D R+RER+RDA ++E+E+ ++ R+ + +R
Sbjct: 119 KE-RNRQKERERETEREGERGRDRQTDGQRERERQRDA-EKERERQTDRERQRQTERNRQ 176
Query: 119 KDREKEKDRRARKEELRQ------TVAHHNLLGQE-TRDRQLLERAERK-------GRSV 164
K+RE+EK+R+ R+E RQ T H+ G+E R+R+ ERK R
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
Query: 165 SKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRD 224
R EK + ER E R +ER+ + +D + + + +R+ ++ E DR+
Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE 296
Query: 225 NKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAK 284
+ + + +RE+ + + N ++ ER +E+ + D E+ + +RK K
Sbjct: 297 TERKRE----RQRERERERERNRKRERERERERERERQRETERDREKER---ERKRKRQT 349
Query: 285 DEPRKRESQNGE------HRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSS 338
+ R+R Q G R R +RD S++ E R+ +D+ R+ E+
Sbjct: 350 EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEK--- 406
Query: 339 VWWKLDQRPGGEETVEIEKEETDLENAR 366
R G ET + + E D E+ R
Sbjct: 407 ------DRDGQRETEKQREREKDRESER 428
Score = 116 bits (290), Expect = 1e-25
Identities = 79/303 (26%), Positives = 145/303 (47%), Gaps = 14/303 (4%)
Query: 26 QSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERD 85
Q+ ++++ + REK ++ E + KE + D + R R+R E T E+ R +R
Sbjct: 170 QTERNRQKEREREKNRQERRERERQREKENKTEDRHSE-RGRERERERETETETER-KRQ 227
Query: 86 RDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDR---RARKEELRQTVAHHN 142
DR+R+R+R +RE+EK E+ R +E+ R K+RE+E+DR R R+++ R+
Sbjct: 228 TDRERDRQRKT-EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
Query: 143 LLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPL 202
+ RDR+ + ER+ + R E++ ER E R R+R+ + K+
Sbjct: 287 RQRRTERDRETERKRERQR---ERERERERNRKRERERERERERERQRETERDREKERER 343
Query: 203 KYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEK--- 259
K E R+R+ R RE+ RE+ + ++E+ D+ +R KE+
Sbjct: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403
Query: 260 --RHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENL 317
+ ++G +++ + DR+ + ++ R+RE Q G R+R + R + L
Sbjct: 404 TEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
Query: 318 VRN 320
N
Sbjct: 464 YVN 466
Score = 107 bits (268), Expect = 5e-23
Identities = 105/458 (22%), Positives = 194/458 (42%), Gaps = 45/458 (9%)
Query: 56 RCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAK--DREKEKLKEKHREAEK 113
R R Q++ R + + H + ER+R ++RERRR+ + +RE ++ +E+ RE ++
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 114 SHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKD 173
R + RE+++DR KE RQT RDRQ K R+ K R E +
Sbjct: 88 HRKRDRHRERQRDR--EKERERQT--------DRERDRQ-----REKERNRQKERERETE 132
Query: 174 EDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSST 233
+ ERG + + RER+ Q K+ + ++ R+R+ +E +R+ +E+
Sbjct: 133 REGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ-KEREREKNRQERRER 191
Query: 234 REKREKYSKEKSNSFSDKGEERHKEK-------RHKEGFHFDDERHQSNVDRKEKSAKDE 286
+REK +K + + S++G ER +E+ R ++ D + ++ +R++++ ++
Sbjct: 192 ERQREKENKTE-DRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERER 250
Query: 287 PRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLD-Q 345
+RE++ + R R RD Q + + D +R+ E K + Q
Sbjct: 251 ASERETERDKERERERDRDRDRDRRQ------KERERQTDRKRQRRTERDRETERKRERQ 304
Query: 346 RPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKL 405
R E K E + E R E D E + + D N RE
Sbjct: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGR 364
Query: 406 EELPLAQKKEIQEIQRAINAENERIGELSLKLFQKR---------GRTEFEKEPRTDTNS 456
+ +++E + +++ ER + ++R G+ E EK+ + +
Sbjct: 365 RQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424
Query: 457 SPSRASVCGIFVDFASASHRQKSR---TQALKQKMRST 491
R G + R + R QA +Q+ RST
Sbjct: 425 ESERGRERGREREKQKGRERDRERQTDRQAGRQRKRST 462
Score = 77.0 bits (188), Expect = 9e-14
Identities = 77/386 (19%), Positives = 155/386 (40%), Gaps = 20/386 (5%)
Query: 87 DRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARK-EELRQTVAHHNLLG 145
D R R + + L + H++A+ R ++R+KE++RR K + R+T
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDAD-GDDRERNRQKERERRREKRQTERETDRKRERRR 83
Query: 146 QETRDRQLLERAER-KGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKY 204
++ R R+ ER + R + R +++ D +R E ++ RER+ + +
Sbjct: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD--- 140
Query: 205 WLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEG 264
+ +G+R + R+ +++ + R+ R+++ + +++K +ER + +R +E
Sbjct: 141 --RQTDGQRERERQRDAEKE-RERQTDRERQRQTERNRQKEREREKNRQERRERERQREK 197
Query: 265 FHFDDERHQSNVDRKEKSAKDE---------PRKRESQNGEHRNRGASSKRDGTSSQHAE 315
+ ++RH +E+ + E R+R+ Q R R ++R+ S + E
Sbjct: 198 ENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE 257
Query: 316 -NLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASC 374
+ R +D+D R +E + QR + K E E R
Sbjct: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 375 EDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGELS 434
E + E + + + D R++ E+ + ++ R AE ER E
Sbjct: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRR-QAERERERERE 376
Query: 435 LKLFQKRGRTEFEKEPRTDTNSSPSR 460
R R E E++ D R
Sbjct: 377 RDRQSAREREERERDRDRDRQKERER 402
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 13/117 (11%)
Query: 26 QSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARS-------RDRVAEVHTAKE 78
Q+G + RE++ +E + +E R RD D+D + +DR + T K+
Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
Query: 79 SPR-----GERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRAR 130
R ER R+R RER + K RE+++ ++ R+A + R R AR
Sbjct: 418 REREKDRESERGRERGREREKQ-KGRERDRERQTDRQAGRQRKRSTLYVNPPPRTAR 473
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 108 bits (269), Expect = 4e-23
Identities = 104/391 (26%), Positives = 184/391 (47%), Gaps = 49/391 (12%)
Query: 29 GSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDR 88
G ++ R +RE+ R S + + RD ++ R DRV + R ER R+R
Sbjct: 627 GERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRV-------DDRRDERARER 679
Query: 89 QRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQET 148
RER RD ++RE+E+ +E+ RE EK ++R +E++R KE R+
Sbjct: 680 DRERERD-RERERERERERDREREKERELERERAREREREREKERDRE------------ 726
Query: 149 RDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYK 208
RDR +R + R + R EK+ + ER + +RER RER+ + ++ +
Sbjct: 727 RDR---DRDHDRERERERERDREKEREREREERERERE-RERERERERERER-------E 775
Query: 209 EEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHK-EGFHF 267
ER + R+ D ++K + + REKRE+ ++++ D +ER +KR++ EG
Sbjct: 776 RARERDKERERQRDWEDKDKGRDDRREKREEIREDRNP--RDGHDERKSKKRYRNEG--- 830
Query: 268 DDERHQSNVDRKEKSA-KDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRN-HGKDK 325
QS R+E S D + +N +HR + + S +L + G+ K
Sbjct: 831 SPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWK 890
Query: 326 DSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETD-LENARADAYTASCEDDFEDYEDD 384
+ RK +E SS ++ + +V+ ++E+T+ LE++R A ED E
Sbjct: 891 EEDRKPERKE-SSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRE-- 947
Query: 385 FEVCDGDDDESSNEPESREKLEELPLAQKKE 415
D + +E + + K+++ P+ +KKE
Sbjct: 948 ------TSDRAHDENKKKAKIQKKPIKKKKE 972
Score = 84.3 bits (207), Expect = 5e-16
Identities = 95/443 (21%), Positives = 177/443 (39%), Gaps = 39/443 (8%)
Query: 31 KEERKHREKKLRKESEMDLPEHKEPRCRDPDQDAR-SRDRVAEVHTAKESPRGERDRDRQ 89
K+ R+ RE + + S D + +EPR +DAR +RDR E+ +++ RD
Sbjct: 428 KDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDR-RELRDSRDMRDSREMRDYS 486
Query: 90 RERRRDAKDREKEKLKEKH----REAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLG 145
R+ + R+ ++ H RE +H R +D E+ R + LR+ + +
Sbjct: 487 RDTKESRDPRDSRSTRDAHDYRDREGRDTH-RKEDTYPEESRSYGRNHLREESSRTEIRN 545
Query: 146 QETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYW 205
+ + + R +R GRS +V E E RG + Y DS + Y
Sbjct: 546 ESRNESRSEIRNDRMGRSRGRV--PELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSY- 602
Query: 206 LYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEE---RHKEKRHK 262
+ R P+RDN+ + + S+ E+R + N D+ RH+ +
Sbjct: 603 ---------PERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGR--N 651
Query: 263 EGFHFDDERHQSNV----DRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAEN-- 316
+ D+ R + V DR+++ A++ R+RE R R R+ + E
Sbjct: 652 DELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERER 711
Query: 317 -LVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCE 375
R ++K+ R+ + + ++ E+ E E+EE + E R E
Sbjct: 712 AREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERE 771
Query: 376 DDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGELSL 435
+ E + + E + E ++K + +++EI+E + + +ER S
Sbjct: 772 RERERARE-----RDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDER---KSK 823
Query: 436 KLFQKRGRTEFEKEPRTDTNSSP 458
K ++ G + P+ SP
Sbjct: 824 KRYRNEGSPSPRQSPKRRREHSP 846
Score = 78.6 bits (192), Expect = 3e-14
Identities = 97/427 (22%), Positives = 176/427 (41%), Gaps = 45/427 (10%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E + R ++ + D R+ ++ ++E + REK+ +E + D +H R R+ +
Sbjct: 684 ERDRERERERERERDREREKERELERERAREREREREKERDRERDRDR-DHDRERERERE 742
Query: 62 QDA-RSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKD 120
+D + R+R E + ER+R+R+RER R RE++K +E+ R+ E +G+D
Sbjct: 743 RDREKEREREREERERERERERERERERERERER---ARERDKERERQRDWE-DKDKGRD 798
Query: 121 REKEKDRRARKEELRQ----TVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDS 176
DRR ++EE+R+ H ++++ R E + +S + R D D+
Sbjct: 799 -----DRREKREEIREDRNPRDGHDE---RKSKKRYRNEGSPSPRQSPKRRREHSPDSDA 850
Query: 177 ERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREK 236
+D+ ++R + L E+ R+ R + D K K S+R
Sbjct: 851 YNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTED-----RQGRWKEEDRKPERKESSRRY 905
Query: 237 REKYSKEKSNSFSDKGEERH--KEKRHKE----GFHFDDER------HQSNVDRKEKSAK 284
E+ KEK +S + E+ + R + G H ++R H N + + K
Sbjct: 906 EEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKK 965
Query: 285 DEPRKRESQNGEHRNRGASSKRDG-----TSSQHAENLVRNHGKDKDSRRKHGHEEGSSV 339
+K+E G R ++ DG Q +++ + K K E
Sbjct: 966 PIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQS 1025
Query: 340 WWKLDQR----PGGEETVEI-EKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDE 394
K R EE VE+ + LE+++ TA + ED D EV + +
Sbjct: 1026 KKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTA 1085
Query: 395 SSNEPES 401
++ P S
Sbjct: 1086 TATTPGS 1092
Score = 60.5 bits (145), Expect = 8e-09
Identities = 74/357 (20%), Positives = 136/357 (38%), Gaps = 30/357 (8%)
Query: 30 SKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQ 89
S + KK RK S + P + R +Q + R SP D
Sbjct: 223 SSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTP-------SPPPPIPEDIA 275
Query: 90 RERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETR 149
++ K + K++++EK R+ + RG+D E+++++R + HH+ +
Sbjct: 276 LGKKYKEKYKVKDRIEEKTRDGK---DRGRDFERQREKRDKPRSTSPAGQHHSPISSRHH 332
Query: 150 DRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERR----YRERKLQYGDSKDNPLKYW 205
+ + S S R +R RR Y L K +P ++
Sbjct: 333 SSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHR 392
Query: 206 LYKEEGERRHRKPREPDRDNKHREKSSTREK--REKYSKEKSNSFSDKGEER-HKEKRH- 261
E R + D +H + TR K REK S+E+ D+ R H++ R
Sbjct: 393 SPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREP 452
Query: 262 KEGFHFDDERHQSNVDRKE-KSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRN 320
++G D R DR+E + ++D RE ++ + + RD S++ A +
Sbjct: 453 RDGRDRRDAR--DTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDY--- 507
Query: 321 HGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDD 377
+D++ R H E+ + + R G + E T++ N + + +D
Sbjct: 508 --RDREGRDTHRKED----TYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRND 558
Score = 52.8 bits (125), Expect = 2e-06
Identities = 64/302 (21%), Positives = 121/302 (40%), Gaps = 33/302 (10%)
Query: 8 TKDDTWKADDLRKHLWAIQSGGSKEERKHREKKL--RKESEMDLPEHKEP-RCRDPD-QD 63
+ D ++ D + + GS++ K + ++ ++S +D + EP R D QD
Sbjct: 1210 SNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQD 1269
Query: 64 ARSR-------DRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHS 116
+RS + +VH+ S RDR ++R+R ++RE+E+ + RE ++
Sbjct: 1270 SRSHSSRRSSPESDRQVHSRSGS-FDSRDRLQERDRYEHDRERERERRDTRQREWDRDAD 1328
Query: 117 RGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDS 176
+ R +++DR +E R+ +L DR ER SV + R ++D
Sbjct: 1329 KDWPRNRDRDRLRERERERERDKRRDL------DR---ERERLISDSVERDRDRDRDRTF 1379
Query: 177 ERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREK 236
E + +R E KL+ +D E R D++ ++ S +
Sbjct: 1380 ESSQIESVKRC-EAKLEGEHERDL-----------ESTSRDSLALDKERMDKDLGSVQGF 1427
Query: 237 REKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGE 296
E E++ S +E + H G + + D ++ + KRE Q E
Sbjct: 1428 EETNKSERTESLEAGDDESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDE 1487
Query: 297 HR 298
+
Sbjct: 1488 EK 1489
Score = 49.3 bits (116), Expect = 2e-05
Identities = 88/432 (20%), Positives = 156/432 (36%), Gaps = 85/432 (19%)
Query: 65 RSRDRVAEVHTAKESPRGERDRDRQRERRRDAK-DREKEKLKEKHREAEKSHSRGKDREK 123
R + + + E P G+ R+R + +R+D + +K +E K SRG+ REK
Sbjct: 66 RGKGYSSNYRRSPERPTGDL-RERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREK 124
Query: 124 E-----KDRRARKEE----------------LRQTVAHHNLLGQETR---------DRQL 153
E K+R EE + H L + + +++
Sbjct: 125 EDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQEN 184
Query: 154 LERAE----RKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKD-------NPL 202
+E+ E +K S VRS+ S R +R K KD +PL
Sbjct: 185 MEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPL 244
Query: 203 -------KYWLYKEEGERRHRKPREPDRD----NKHREKSSTREKREKYSKEKSNSFSDK 251
K K++G R P D K++EK +++ E EK+ D+
Sbjct: 245 LDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIE----EKTRDGKDR 300
Query: 252 GE--ERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDE-----------PRKRESQNGEHR 298
G ER +EKR K +H S + + S+ + PR++ + + ++
Sbjct: 301 GRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQ 360
Query: 299 NRGASSKRDGTSSQHAENLVRNHGKDKDSRR--------KHGHEEGSSVWWKLDQRPGGE 350
R S + +L K R +H HE S D+R
Sbjct: 361 RTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQ---SHDRRHERR 417
Query: 351 ETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKL-EELP 409
E +++ +++R + + D+ DD E DG D + + R +L +
Sbjct: 418 EDTRGKRDRE--KDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRD 475
Query: 410 LAQKKEIQEIQR 421
+ +E+++ R
Sbjct: 476 MRDSREMRDYSR 487
Score = 40.0 bits (92), Expect = 0.012
Identities = 65/285 (22%), Positives = 106/285 (37%), Gaps = 39/285 (13%)
Query: 139 AHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSK 198
A H + R L + + ++RS D GD+ R+ ++ + S+
Sbjct: 1178 AQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRK----RVLHSGSR 1233
Query: 199 DNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKE 258
D K + GER+ R + R R SS R+ +S +S+ SD+
Sbjct: 1234 DRE-KTKSLEITGERKSRID-QLKRGEPSRSTSSDRQDSRSHSSRRSSPESDR------- 1284
Query: 259 KRHKEGFHFDD-----ERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQH 313
+ H FD ER + DR+ + + + R+RE ++ + RD +
Sbjct: 1285 QVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERE 1344
Query: 314 AENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQ-RPGGEETVEIE-----------KEETD 361
E R K +D R+ SV D+ R E+ +IE + E D
Sbjct: 1345 RE---RERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERD 1401
Query: 362 LENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLE 406
LE+ D+ D E + D G E +N+ E E LE
Sbjct: 1402 LESTSRDSLAL----DKERMDKDLGSVQG--FEETNKSERTESLE 1440
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 107 bits (266), Expect = 8e-23
Identities = 87/321 (27%), Positives = 154/321 (47%), Gaps = 26/321 (8%)
Query: 32 EERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRG-ERDRDRQR 90
EE K +++K R+E E + E + R R+ ++ R R+R E KE R ER+RDR R
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351
Query: 91 ERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRD 150
+R ++ +DR++++ +++ R+ E+S R KDR + +++ +E R+ + R+
Sbjct: 352 DRTKE-RDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERE 410
Query: 151 RQLLERAERKGRSVSKVRSEEKDEDSERGDEDR-ERRYRERKLQYGDSK-DNPLKYWLYK 208
R ER + R + R ++K D E +ED ERR ERKL+ ++ LK W +
Sbjct: 411 R---EREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIR 467
Query: 209 EEGERRHRKPREPDRDNKHREKSSTREKR-----EKYSKEKSNSFSDKGEERHKEKRHKE 263
E + R + +E +R+ + R + + KR E Y ++ + +G K R +E
Sbjct: 468 ERKKTREYE-KEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDRE 526
Query: 264 GFHFDDERHQSNVDRKEKSAKDEPRKRESQNG--------EHRNRGASSKRDGTSSQHAE 315
DER + ++EK +E R+R G + + A +R Q E
Sbjct: 527 KEMEADERDR----KREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPE 582
Query: 316 NLVRNHGK-DKDSRRKHGHEE 335
+ K +K+ +R+ EE
Sbjct: 583 SEEEEEEKQEKEEKREEPMEE 603
Score = 100 bits (250), Expect = 6e-21
Identities = 113/452 (25%), Positives = 183/452 (40%), Gaps = 74/452 (16%)
Query: 30 SKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQ 89
S+E K R+ + E E KE ++ +++ R R+R ER+R+R+
Sbjct: 278 SREISKFRDTHKKLEEEKG---KKEKERQEIEKERRERER-------------ERERERE 321
Query: 90 RERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETR 149
R R ++RE+E+ KEK RE E+ R +DR KE+DR +E R
Sbjct: 322 RREREREREREREREKEKERERERERDRDRDRTKERDRDRDRE--------------RDR 367
Query: 150 DRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKE 209
DR +R R+ + RS EK D ER E R RER
Sbjct: 368 DR---DRERSSDRNKDRSRSREKSRDRERERERERERERER------------------- 405
Query: 210 EGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDD 269
ER + RE +R+ RE+ REK +K +E+ D E R E++ +E
Sbjct: 406 --ERERERERERERE---REREREREKDKKRDREEDE--EDAYERRKLERKLREKEAAYQ 458
Query: 270 ERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRR 329
ER ++ R+ K ++ ++ E + R +KR + + ++ D+D +
Sbjct: 459 ERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR-------LKEFLEDYDDDRDDPK 511
Query: 330 KHGHEEGSSVWWKLDQRPGGEETVEIE--KEETDLENARADAYTASCED-DFEDYEDDFE 386
+ GS++ +L R E E + +E+ +LE R D D E + E
Sbjct: 512 ---YYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQE 568
Query: 387 VCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEF 446
+ EPES E+ EE +K+E +E E E+ L L
Sbjct: 569 AERRRQPQIKQEPESEEEEEE--KQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSV 626
Query: 447 EKEPRTDTNSSPSRASVCGIFVDFASASHRQK 478
T ++P S CGI + ++ +Q+
Sbjct: 627 SSASGNATPNTPGDESPCGIIIPHENSPDQQQ 658
Score = 76.6 bits (187), Expect = 1e-13
Identities = 103/453 (22%), Positives = 186/453 (41%), Gaps = 92/453 (20%)
Query: 63 DARSRDRVAEVHTAKESPRG-----------ERDRDRQRERRRDAKDREKEKLKEKHREA 111
DA+++ ++ E K++ G E D + +RR E L ++
Sbjct: 162 DAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSE 221
Query: 112 EKSHSRGKDREKEKDRRARKEEL--RQTVAH---HNLLGQETRDRQLLERAERK--GRSV 164
+ S+ D K ++ +KE++ R VA + L+ +E + +E +R R +
Sbjct: 222 LNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREI 281
Query: 165 SKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHR-KPREPDR 223
SK R K + E+G +++ER+ E+ ERR R + RE +R
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEK---------------------ERRERERERERER 320
Query: 224 DNKHREKSSTREK-REKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQS-----NVD 277
+ + RE+ RE+ REK + + D+ +R KE+ D +R + N D
Sbjct: 321 ERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKD 380
Query: 278 RKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGS 337
R K R+RE + R R +R+ + E R ++KD +R +E
Sbjct: 381 RSRSREKSRDRERERERERERERERERERERERERERER-EREREREKDKKRDREEDEED 439
Query: 338 SVW---------------------WKLDQRPGGEETVEIEKE-ETDLENARADAYTASCE 375
+ W++ +R ++T E EKE E + E R A A
Sbjct: 440 AYERRKLERKLREKEAAYQERLKNWEIRER---KKTREYEKEAEREEERRREMAKEAKRL 496
Query: 376 DDF-EDYEDDFE---VCDGD-------DDESSNEPESREKLEELPLAQKKEIQEIQRAIN 424
+F EDY+DD + G D E E + R++ E K+E++EI++ +
Sbjct: 497 KEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKRE-----KEELEEIRQRLL 551
Query: 425 AENERIGELSLKLF----QKRGRTEFEKEPRTD 453
AE + L+ ++R + + ++EP ++
Sbjct: 552 AEGHPDPDAELQRMEQEAERRRQPQIKQEPESE 584
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 100 bits (250), Expect = 6e-21
Identities = 69/252 (27%), Positives = 131/252 (51%), Gaps = 19/252 (7%)
Query: 40 KLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDR 99
KL E +M H C P + R+R E+ T KE + ER+ +R++ERR K R
Sbjct: 12 KLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKK-ERESERKKERREREK-R 69
Query: 100 EKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAER 159
++E+ KE+ RE K +G+ +++E++R+ R+ E N G+E R+ E+ ER
Sbjct: 70 KREREKERKRERGKKEKKGERKKEERERKKRRRE------KENKEGEEKEKRKKKEKKER 123
Query: 160 KGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPR 219
GR+ + + E+ E+ +R E+R+ R R+++ + + + K K+ GE+ +
Sbjct: 124 -GRTSKEGKERERKEERKR--EERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180
Query: 220 EPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRK 279
+ ++ K RE++ K+E+ KE+ ER KE++ KE + ++ + R+
Sbjct: 181 KERKERKKRERNRKERKKERERKER--------RERKKERKKKEERKKERQKDRQTNWRE 232
Query: 280 EKSAKDEPRKRE 291
++ K E ++R+
Sbjct: 233 KERGKRERKERK 244
Score = 90.5 bits (223), Expect = 8e-18
Identities = 74/258 (28%), Positives = 130/258 (50%), Gaps = 47/258 (18%)
Query: 26 QSGGSKEER-KHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGER 84
Q G E R + RE + RKE + + ++ R+ ++ R R++ + K+ +GER
Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGER 90
Query: 85 DRD-RQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNL 143
++ R+R++RR K+ ++ + KEK ++ EK RG+ ++ K+R ++E R+
Sbjct: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKK-ERGRTSKEGKERERKEERKRE------- 142
Query: 144 LGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLK 203
ER ER E K E+ E+ E +ER+ RERK Q G+ ++
Sbjct: 143 -----------ERKER----------ERKKEEREKERERKERKKRERK-QVGEKEEE--- 177
Query: 204 YWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKE 263
++E ER+ RK RE R+ K R+K R++R + KE+ K EER KE++
Sbjct: 178 ----RKEKERKERKKRE--RNRKERKKERERKERRERKKERK-----KKEERKKERQKDR 226
Query: 264 GFHFDDERHQSNVDRKEK 281
++ E+ + +RKE+
Sbjct: 227 QTNW-REKERGKRERKER 243
Score = 76.3 bits (186), Expect = 1e-13
Identities = 66/257 (25%), Positives = 111/257 (43%), Gaps = 46/257 (17%)
Query: 101 KEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERK 160
+ +++E+ RE E K+RE E+ + R+ E R+ R+R+ ER +
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRK------------REREK-ERKRER 81
Query: 161 GRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPRE 220
G+ K++ ER E+RER+ R R+ K+N KE E+ RK +E
Sbjct: 82 GK---------KEKKGERKKEERERKKRRRE------KEN-------KEGEEKEKRKKKE 119
Query: 221 PDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKE 280
+ ++ RE++E+ +E+ K EER KE+ KE + +RK+
Sbjct: 120 KKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE---------RKKRERKQ 170
Query: 281 KSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVW 340
K+E RK E + E + R + K + E R + K RK ++
Sbjct: 171 VGEKEEERK-EKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTN 229
Query: 341 WKLDQRPGGEETVEIEK 357
W+ +R G E E +K
Sbjct: 230 WREKER-GKRERKERKK 245
Score = 70.5 bits (171), Expect = 8e-12
Identities = 48/170 (28%), Positives = 81/170 (47%), Gaps = 5/170 (2%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E GK+ K + K + RK + EE++ R+KK +KE E KE ++
Sbjct: 80 ERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEE- 138
Query: 62 QDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRG-KD 120
R R+ E KE ER+R +++R R ++E+ KEK R+ K R K+
Sbjct: 139 ---RKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195
Query: 121 REKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSE 170
R+KE++R+ R+E ++ + +DRQ R + +G+ K R +
Sbjct: 196 RKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 57.0 bits (136), Expect = 9e-08
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 4/157 (2%)
Query: 210 EGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDD 269
E + +K RE +R + RE+ + +REK K + KG ER KE+R ++ +
Sbjct: 46 ETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKG-ERKKEERERKKRRREK 104
Query: 270 ERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRR 329
E + K K + + R R S+ G+ R R KR+ + + R +++ R+
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK 164
Query: 330 KHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENAR 366
K E V K ++R E ++E E +
Sbjct: 165 K---RERKQVGEKEEERKEKERKERKKRERNRKERKK 198
Score = 50.8 bits (120), Expect = 7e-06
Identities = 52/225 (23%), Positives = 96/225 (42%), Gaps = 25/225 (11%)
Query: 207 YKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKE--KRHKEG 264
++ E R R+ K RE +E+RE+ +++ ++ +ER +E K+ K+G
Sbjct: 34 WQSEIREREREIETRKEGKKERESERKKERREREKRKR-----EREKERKRERGKKEKKG 88
Query: 265 FHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKD 324
+ER + R+EK K+ K + + E + RG +SK +G + E R K+
Sbjct: 89 ERKKEERERKK-RRREKENKEGEEKEKRKKKEKKERGRTSK-EGKERERKEERKREERKE 146
Query: 325 KDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDD 384
++ +++ +E K +R E E KE+ E + + + + E
Sbjct: 147 RERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE----- 201
Query: 385 FEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENER 429
E + R+K EE +KKE Q+ ++ E ER
Sbjct: 202 -------RKERRERKKERKKKEE----RKKERQKDRQTNWREKER 235
Score = 49.7 bits (117), Expect = 1e-05
Identities = 47/233 (20%), Positives = 90/233 (38%), Gaps = 29/233 (12%)
Query: 220 EPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRK 279
+P ++ RE+ E R++ KE+ + + ER K KR +E + + + K
Sbjct: 31 QPGWQSEIREREREIETRKEGKKERESERKKERREREKRKRERE----KERKRERGKKEK 86
Query: 280 EKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAE-NLVRNHGKDKDSRRKHGHEEGSS 338
+ K E R+R+ + E N+ K + E GK+++ + + EE
Sbjct: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146
Query: 339 VWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNE 398
K ++R E E +K E +V + +++ E
Sbjct: 147 RERKKEEREKERERKERKKRERK------------------------QVGEKEEERKEKE 182
Query: 399 PESREKLEELPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFEKEPR 451
+ R+K E +KKE + +R + + E K QK +T + ++ R
Sbjct: 183 RKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKER 235
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 99.8 bits (247), Expect = 1e-20
Identities = 82/316 (25%), Positives = 143/316 (45%), Gaps = 37/316 (11%)
Query: 29 GSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDR 88
G++E +H E++ + L + PR +RSR E H + R E +R++
Sbjct: 247 GAEEIDRHVERRRSRSPRRSLSPRRSPR------RSRSRSHHREGHGSSSFDR-ELEREK 299
Query: 89 QRER-RRDAKDREKEKLKEKH--REAEKSHSRGKDREKEKDR-RARKEELRQTVAHHNLL 144
+R+R R+AK+REKE+ + + R E+ SR ++R + + R R RK + R
Sbjct: 300 ERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRD-------- 351
Query: 145 GQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKY 204
RDR+ + ER R ++D D ERG+E + R R R+ ++
Sbjct: 352 ----RDREREKENERG-------RRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEE 400
Query: 205 WLYKEE-GERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKE 263
+KE+ +RRHR + + K +S +RE++ + S+ +S + + R KEK K
Sbjct: 401 KKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHR-SRSRSRNAGKRSRSRSKEKSSK- 458
Query: 264 GFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGK 323
H ++ + +SN + S +S+ EH S++ S + + R+H
Sbjct: 459 --HKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHK--RDHSD 514
Query: 324 DKDSRRKHGHEEGSSV 339
KD KH S+
Sbjct: 515 SKDQSDKHDRRRSQSI 530
Score = 86.7 bits (213), Expect = 1e-16
Identities = 76/280 (27%), Positives = 129/280 (46%), Gaps = 31/280 (11%)
Query: 28 GGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRD 87
G S +R+ +K R+ E + E ++ R R +RS DR E ++ R R R
Sbjct: 287 GSSSFDRELEREKERQRLEREAKEREKERRR-----SRSIDRGLERRRSRSRER-HRSRS 340
Query: 88 RQRERRRDAKDREKEKLKE----KHREAEKSHSRGKDREKEKDR-RARKEELRQTVAHHN 142
R R+R+ D +DR++E+ KE + R+ + RG +REKE++R R R +E R
Sbjct: 341 RSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSR----- 395
Query: 143 LLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPL 202
G+ + ++ +R+ R + +EK R E R+ R R R G +
Sbjct: 396 --GEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRE-RKHRSRSRSRNAGKRSRSRS 452
Query: 203 KYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKY--SKEKSNSFSDKGEERHKEKR 260
K K + E + + + ++ R S + K+ ++ SKEKS S R KE+
Sbjct: 453 KEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRS-----RSKERS 507
Query: 261 HKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNR 300
HK H D + DR+ + + ++ESQ +H+N+
Sbjct: 508 HKRD-HSDSKDQSDKHDRR----RSQSIEQESQEKQHKNK 542
Score = 79.0 bits (193), Expect = 2e-14
Identities = 96/367 (26%), Positives = 155/367 (42%), Gaps = 60/367 (16%)
Query: 50 PEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREK-EKLKEKH 108
P P ++ DQ ++R R + K+ G + DR ERRR R +
Sbjct: 219 PRIPVPVQKNIDQQIKTRPRKIK----KDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPR 274
Query: 109 REAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVR 168
R +SH R DR +E+ RQ L +E ++R E+ R+ RS+
Sbjct: 275 RSRSRSHHREGHGSSSFDRELEREKERQR------LEREAKER---EKERRRSRSI---- 321
Query: 169 SEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHR 228
+RG E R R RER S+D +G+RR DRD + R
Sbjct: 322 --------DRGLERRRSRSRERHRSRSRSRDR---------KGDRR-------DRD-RER 356
Query: 229 EKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNV-DRKEKSAKDEP 287
EK + R +R +K ++G ER KE R + ++R + V ++K K KD+
Sbjct: 357 EKENERGRRRDRDYDK-----ERGNEREKE-RERSRERSKEQRSRGEVEEKKHKEDKDDR 410
Query: 288 R----KRESQNGEHRNRGASSKRDGTS---SQHAENLVRNHGKDKDSRRKHGHEEGSSVW 340
R KR+S+ + +R S +R S S++A R+ K+K S+ K+ +E S+
Sbjct: 411 RHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR 470
Query: 341 WKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFE-DYEDDFEVCDGDDDESSN-- 397
+ + + + +K E ++ + S E + D+ D + D D S
Sbjct: 471 SRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSI 530
Query: 398 EPESREK 404
E ES+EK
Sbjct: 531 EQESQEK 537
Score = 68.9 bits (167), Expect = 2e-11
Identities = 56/221 (25%), Positives = 95/221 (42%), Gaps = 17/221 (7%)
Query: 20 KHLWAIQSGGSKEERKHREKKLRKESEM----DLPEHKEPRCRDPDQDARSRDRVAEVHT 75
+H +S K +R+ R+++ KE+E D KE + RSR+R E +
Sbjct: 335 RHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRS 394
Query: 76 AKESPRGERDRDRQRERRRDAK-DREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEEL 134
E + D+ R RD K D +KEK + R E+ H R + R + +R+R
Sbjct: 395 RGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKH-RSRSRSRNAGKRSRSRSK 453
Query: 135 RQTVAHHNLLGQETRDRQLLERAERKGR--SVSKVRSEEKDEDSERGDEDRERRYRERKL 192
++ H N +++ R R+ +GR SV K + E E+ + + R K
Sbjct: 454 EKSSKHKNESKEKSNKR---SRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKR 510
Query: 193 QYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSST 233
+ DSKD K+ RR + + ++ +H+ K T
Sbjct: 511 DHSDSKDQSDKH------DRRRSQSIEQESQEKQHKNKDET 545
Score = 37.0 bits (84), Expect = 0.099
Identities = 37/139 (26%), Positives = 58/139 (41%), Gaps = 23/139 (16%)
Query: 6 RRTKDDTWKADDLRKHLWAIQSGGSKEERKHRE--------KKLRKESEMDLPEHKEPRC 57
RR +DD + +KH S ERKHR K+ R S+ +HK
Sbjct: 410 RRHRDDKRDSKKEKKH-----SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESK 464
Query: 58 RDPDQDARS-----RDRVAEVHTAKESPRGE--RDRDRQRER--RRDAKDREKEKLKEKH 108
++ +RS D V + + SP E R R R +ER +RD D + + K
Sbjct: 465 EKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDR 524
Query: 109 REAEKSHSRGKDRE-KEKD 126
R ++ ++++ K KD
Sbjct: 525 RRSQSIEQESQEKQHKNKD 543
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 99.8 bits (247), Expect = 1e-20
Identities = 73/300 (24%), Positives = 135/300 (45%), Gaps = 17/300 (5%)
Query: 30 SKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQ 89
S+ K ++ R +S+ H R R D+ RS+ + ++E R R R
Sbjct: 316 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR-RRSKSPHKKRSKSRER-RKSRSRSHS 373
Query: 90 RERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETR 149
R++R+D +++ KEK + K ++ EK R K+REKEK+R K+ ++ ++ R
Sbjct: 374 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR 433
Query: 150 DRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKE 209
+R ER + + K + +E+D++ ER ++DR + E++ + S+ P Y
Sbjct: 434 ER---EREKEHEKDRDKEKEKEQDKEKER-EKDRSKEIDEKRKKDKKSRTPPRSY----- 484
Query: 210 EGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDD 269
RR R R + R S + + ++ S S S + + +KR KE H +
Sbjct: 485 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 544
Query: 270 ERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRR 329
R + KS+ D K E + ++S ++ ++ ++ V DKD+ R
Sbjct: 545 RRERERSTSMRKSSNDRDGK------EKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPR 598
Score = 96.7 bits (239), Expect = 1e-19
Identities = 79/269 (29%), Positives = 123/269 (45%), Gaps = 31/269 (11%)
Query: 30 SKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGE-RDRDR 88
S+E RK R + ++ D E + + R ++D R ++R E KE RG+ +DRD+
Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKD-REKEREREKEREKEKERGKNKDRDK 419
Query: 89 QRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQET 148
+RE KDREK+K K++ RE EK H KDR+KEK++ KE+ R ++
Sbjct: 420 ERE-----KDREKDKEKDREREREKEHE--KDRDKEKEKEQDKEKER----------EKD 462
Query: 149 RDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYK 208
R +++ E+ ++ +S + RS S +R RR R R +K
Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR-RSRSSSRSPRTSKTIK----- 516
Query: 209 EEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERH-KEKRHKEGFHF 267
R PR ++ +K REK E+ +E+S S +R KEK K
Sbjct: 517 -RKSSRSPSPRSRNKKDKKREKERDHIS-ERRERERSTSMRKSSNDRDGKEKLEKNSTSL 574
Query: 268 DDERHQSNVD---RKEKSAKDEPRKRESQ 293
++ H D KE KD PR E++
Sbjct: 575 KEKEHNKEPDSSVSKEVDDKDAPRTEENK 603
Score = 87.4 bits (215), Expect = 6e-17
Identities = 81/311 (26%), Positives = 142/311 (45%), Gaps = 44/311 (14%)
Query: 5 KRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQD- 63
+RR+K K R+ + S+++RK +K++++ + + ++ R R+ +++
Sbjct: 348 RRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREK 407
Query: 64 ----ARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGK 119
+++DR E +E + E+DR+R+RE+ + KDR+KEK KE+ +E E R K
Sbjct: 408 EKERGKNKDRDKEREKDREKDK-EKDREREREKEHE-KDRDKEKEKEQDKEKE----REK 461
Query: 120 DREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEK--DEDSE 177
DR KE D + +K++ +T + +R ER R+ RS S+ K S
Sbjct: 462 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS-RERRRRRSRSSSRSPRTSKTIKRKSS 520
Query: 178 RGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRH-RKPREPDRDNKHREKSSTREK 236
R R R +++ K E ER H + RE +R R+ S+ R+
Sbjct: 521 RSPSPRSRNKKDK-----------------KREKERDHISERRERERSTSMRKSSNDRDG 563
Query: 237 REKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGE 296
+EK K NS S K +E +KE D VD K+ +E + + + N +
Sbjct: 564 KEKLEK---NSTSLKEKEHNKE---------PDSSVSKEVDDKDAPRTEENKIQHNGNCQ 611
Query: 297 HRNRGASSKRD 307
S+K +
Sbjct: 612 LNEENLSTKTE 622
Score = 85.9 bits (211), Expect = 2e-16
Identities = 81/330 (24%), Positives = 143/330 (43%), Gaps = 40/330 (12%)
Query: 26 QSGGSKEERKHREKK-LRKESEMDLPEHKEPRCRDPDQDARSRDRV-AEVHTAKESPRGE 83
+SG S E + R + R +S H + +RS +R + + S
Sbjct: 296 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 355
Query: 84 RDRDRQRERRRDAKDREKEKLKEKHREA-----EKSHSRGKDREKEKDRRARKEELRQTV 138
+ R + RERR K R + ++K ++ EK + KDREKE++R +E+ ++
Sbjct: 356 KKRSKSRERR---KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERG 412
Query: 139 AHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSK 198
+ + + +DR E+ + K R + + EKD D E+ E + + RE K
Sbjct: 413 KNKDRDKEREKDR---EKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE--------K 461
Query: 199 DNPLKYWLYKEEGERRHRKPREPDR--DNKHREKSSTREKREKYSKEKSNSFSDKGEERH 256
D + +E ++ +K R P R + R +SS+RE+R + S+ S S +
Sbjct: 462 DRSKEI----DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 517
Query: 257 KEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAEN 316
K R R ++ D+K + +D +R + R +S+ RDG E
Sbjct: 518 KSSRS------PSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG-----KEK 566
Query: 317 LVRNHGKDKDSRRKHGHEEGSSVWWKLDQR 346
L +N K+ ++H E SSV ++D +
Sbjct: 567 LEKNSTSLKE--KEHNKEPDSSVSKEVDDK 594
Score = 83.6 bits (205), Expect = 9e-16
Identities = 75/307 (24%), Positives = 136/307 (44%), Gaps = 27/307 (8%)
Query: 81 RGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAH 140
+G R R R + R + + + + + +SH+R + R+K DRR K ++
Sbjct: 304 KGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK--DRRRSKSPHKKRSKS 361
Query: 141 HNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDN 200
+R +R + + + K R +EKD + ER +RE+ RE++ + G +KD
Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER---EREKE-REKEKERGKNKDR 417
Query: 201 PLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKR 260
+ +++ E+ K RE +R+ +H EK +EK ++ KEK E K K+
Sbjct: 418 DKE---REKDREKDKEKDREREREKEH-EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 473
Query: 261 HKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGA------SSKRDGTSSQHA 314
K+ N R+ +S+ E R+R S++ R + SS+ S++
Sbjct: 474 DKKS---RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530
Query: 315 ENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLE----NARADAY 370
++ R +D S R+ E +S+ + R G E ++EK T L+ N D+
Sbjct: 531 KDKKREKERDHISERRE-RERSTSMRKSSNDRDGKE---KLEKNSTSLKEKEHNKEPDSS 586
Query: 371 TASCEDD 377
+ DD
Sbjct: 587 VSKEVDD 593
Score = 71.6 bits (174), Expect = 4e-12
Identities = 81/355 (22%), Positives = 141/355 (39%), Gaps = 48/355 (13%)
Query: 91 ERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRD 150
E A +E E++ ++ REA+ S + E K + R + ++
Sbjct: 265 EMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS 324
Query: 151 RQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERK--LQYGDSKDNPLKYWLYK 208
R+ +++ + RS ++ RS +KD + + + RER+ S+D
Sbjct: 325 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 384
Query: 209 EEGERRHRKPREPDRD-NKHREKSSTREKREKYSKEKS---NSFSDKGEERHKEKRHKEG 264
+E ER K RE +R+ K REK R K + KE+ +K ER +EK H++
Sbjct: 385 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 444
Query: 265 FHFDDERHQSNVDRKEKSAK---DEPRKRE--------SQNGEHRNRGASSKRDGTSSQH 313
+ E+ Q +EK DE RK++ S N R+R +S +R S+
Sbjct: 445 RDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 504
Query: 314 AENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTAS 373
+ R+ K +RK K D++ EKE + R + S
Sbjct: 505 SS---RSPRTSKTIKRKSSRSPSPRSRNKKDKKR--------EKERDHISERRERERSTS 553
Query: 374 CEDDFEDYEDDFEVCDGDDDESSNEPESREKLEE--LPLAQKKEIQEIQRAINAE 426
+SSN+ + +EKLE+ L +K+ +E +++ E
Sbjct: 554 MR------------------KSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590
Score = 54.3 bits (129), Expect = 6e-07
Identities = 43/198 (21%), Positives = 87/198 (43%), Gaps = 18/198 (9%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E + + K+ + + ++H KE+ K +E++ + E+D K+ + R P
Sbjct: 422 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 481
Query: 62 QDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRG--- 118
+ + ++ S R+R R+R R R + +K K + SR
Sbjct: 482 R---------SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 532
Query: 119 KDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSV-SKVRSEEKDEDSE 177
K REKE+D + + E ++ + + + + DR E+ E+ S+ K ++E D
Sbjct: 533 KKREKERDHISERRERERSTS----MRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVS 588
Query: 178 RGDEDRER-RYRERKLQY 194
+ +D++ R E K+Q+
Sbjct: 589 KEVDDKDAPRTEENKIQH 606
Score = 50.4 bits (119), Expect = 9e-06
Identities = 84/387 (21%), Positives = 152/387 (39%), Gaps = 71/387 (18%)
Query: 132 EELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSER------GDEDRER 185
+E+R+TV NL Q T QLLE ++ G V VR + R D++
Sbjct: 178 DEIRRTVYVGNLNSQTTTADQLLEFFKQVG-EVKFVRMAGDETQPTRFAFVEFADQNSVP 236
Query: 186 R--------YRERKLQYGDSKD--------NPLKYWLYKEEGERRHRKPREPDRDNKHRE 229
R + +R L+ S + P EE +R R+ + E
Sbjct: 237 RALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPE 296
Query: 230 KSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRK 289
+ E++ S+ + S S + H ++ + H ++S +K++ P K
Sbjct: 297 SGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK 356
Query: 290 RESQNGEHR-NRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPG 348
+ S++ E R +R S RD K KD+R K +E + D+
Sbjct: 357 KRSKSRERRKSRSRSHSRD---------------KRKDTREKIKEKERVK---EKDREKE 398
Query: 349 GEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEEL 408
E E EKE+ +N +D ++ E D E D+ + REK E
Sbjct: 399 REREKEREKEKERGKN----------KDRDKEREKDRE-----KDKEKDREREREKEHEK 443
Query: 409 PLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFEKEPRTDTNSSPSRASVCGIFV 468
++KE ++ + E ER + S ++ +KR + + + P N+S S
Sbjct: 444 DRDKEKEKEQ-----DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRS------ 492
Query: 469 DFASASHRQKSRTQALKQKMRSTKLLR 495
S+ R++ R+++ + R++K ++
Sbjct: 493 ---SSRERRRRRSRSSSRSPRTSKTIK 516
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 99.8 bits (247), Expect = 1e-20
Identities = 73/300 (24%), Positives = 135/300 (45%), Gaps = 17/300 (5%)
Query: 30 SKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQ 89
S+ K ++ R +S+ H R R D+ RS+ + ++E R R R
Sbjct: 200 SRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR-RRSKSPHKKRSKSRER-RKSRSRSHS 257
Query: 90 RERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETR 149
R++R+D +++ KEK + K ++ EK R K+REKEK+R K+ ++ ++ R
Sbjct: 258 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDR 317
Query: 150 DRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKE 209
+R ER + + K + +E+D++ ER ++DR + E++ + S+ P Y
Sbjct: 318 ER---EREKEHEKDRDKEKEKEQDKEKER-EKDRSKEIDEKRKKDKKSRTPPRSY----- 368
Query: 210 EGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDD 269
RR R R + R S + + ++ S S S + + +KR KE H +
Sbjct: 369 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 428
Query: 270 ERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRR 329
R + KS+ D K E + ++S ++ ++ ++ V DKD+ R
Sbjct: 429 RRERERSTSMRKSSNDRDGK------EKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPR 482
Score = 96.7 bits (239), Expect = 1e-19
Identities = 79/269 (29%), Positives = 123/269 (45%), Gaps = 31/269 (11%)
Query: 30 SKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGE-RDRDR 88
S+E RK R + ++ D E + + R ++D R ++R E KE RG+ +DRD+
Sbjct: 245 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKD-REKEREREKEREKEKERGKNKDRDK 303
Query: 89 QRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQET 148
+RE KDREK+K K++ RE EK H KDR+KEK++ KE+ R ++
Sbjct: 304 ERE-----KDREKDKEKDREREREKEHE--KDRDKEKEKEQDKEKER----------EKD 346
Query: 149 RDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYK 208
R +++ E+ ++ +S + RS S +R RR R R +K
Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR-RSRSSSRSPRTSKTIK----- 400
Query: 209 EEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERH-KEKRHKEGFHF 267
R PR ++ +K REK E+ +E+S S +R KEK K
Sbjct: 401 -RKSSRSPSPRSRNKKDKKREKERDHIS-ERRERERSTSMRKSSNDRDGKEKLEKNSTSL 458
Query: 268 DDERHQSNVD---RKEKSAKDEPRKRESQ 293
++ H D KE KD PR E++
Sbjct: 459 KEKEHNKEPDSSVSKEVDDKDAPRTEENK 487
Score = 87.4 bits (215), Expect = 6e-17
Identities = 81/311 (26%), Positives = 142/311 (45%), Gaps = 44/311 (14%)
Query: 5 KRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQD- 63
+RR+K K R+ + S+++RK +K++++ + + ++ R R+ +++
Sbjct: 232 RRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREK 291
Query: 64 ----ARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGK 119
+++DR E +E + E+DR+R+RE+ + KDR+KEK KE+ +E E R K
Sbjct: 292 EKERGKNKDRDKEREKDREKDK-EKDREREREKEHE-KDRDKEKEKEQDKEKE----REK 345
Query: 120 DREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEK--DEDSE 177
DR KE D + +K++ +T + +R ER R+ RS S+ K S
Sbjct: 346 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSS-RERRRRRSRSSSRSPRTSKTIKRKSS 404
Query: 178 RGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRH-RKPREPDRDNKHREKSSTREK 236
R R R +++ K E ER H + RE +R R+ S+ R+
Sbjct: 405 RSPSPRSRNKKDK-----------------KREKERDHISERRERERSTSMRKSSNDRDG 447
Query: 237 REKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGE 296
+EK K NS S K +E +KE D VD K+ +E + + + N +
Sbjct: 448 KEKLEK---NSTSLKEKEHNKE---------PDSSVSKEVDDKDAPRTEENKIQHNGNCQ 495
Query: 297 HRNRGASSKRD 307
S+K +
Sbjct: 496 LNEENLSTKTE 506
Score = 85.9 bits (211), Expect = 2e-16
Identities = 81/330 (24%), Positives = 143/330 (43%), Gaps = 40/330 (12%)
Query: 26 QSGGSKEERKHREKK-LRKESEMDLPEHKEPRCRDPDQDARSRDRV-AEVHTAKESPRGE 83
+SG S E + R + R +S H + +RS +R + + S
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 239
Query: 84 RDRDRQRERRRDAKDREKEKLKEKHREA-----EKSHSRGKDREKEKDRRARKEELRQTV 138
+ R + RERR K R + ++K ++ EK + KDREKE++R +E+ ++
Sbjct: 240 KKRSKSRERR---KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERG 296
Query: 139 AHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSK 198
+ + + +DR E+ + K R + + EKD D E+ E + + RE K
Sbjct: 297 KNKDRDKEREKDR---EKDKEKDREREREKEHEKDRDKEKEKEQDKEKERE--------K 345
Query: 199 DNPLKYWLYKEEGERRHRKPREPDR--DNKHREKSSTREKREKYSKEKSNSFSDKGEERH 256
D + +E ++ +K R P R + R +SS+RE+R + S+ S S +
Sbjct: 346 DRSKEI----DEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 401
Query: 257 KEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAEN 316
K R R ++ D+K + +D +R + R +S+ RDG E
Sbjct: 402 KSSRS------PSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG-----KEK 450
Query: 317 LVRNHGKDKDSRRKHGHEEGSSVWWKLDQR 346
L +N K+ ++H E SSV ++D +
Sbjct: 451 LEKNSTSLKE--KEHNKEPDSSVSKEVDDK 478
Score = 83.6 bits (205), Expect = 9e-16
Identities = 75/307 (24%), Positives = 136/307 (44%), Gaps = 27/307 (8%)
Query: 81 RGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAH 140
+G R R R + R + + + + + +SH+R + R+K DRR K ++
Sbjct: 188 KGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK--DRRRSKSPHKKRSKS 245
Query: 141 HNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDN 200
+R +R + + + K R +EKD + ER +RE+ RE++ + G +KD
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER---EREKE-REKEKERGKNKDR 301
Query: 201 PLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKR 260
+ +++ E+ K RE +R+ +H EK +EK ++ KEK E K K+
Sbjct: 302 DKE---REKDREKDKEKDREREREKEH-EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 357
Query: 261 HKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGA------SSKRDGTSSQHA 314
K+ N R+ +S+ E R+R S++ R + SS+ S++
Sbjct: 358 DKKS---RTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414
Query: 315 ENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLE----NARADAY 370
++ R +D S R+ E +S+ + R G E ++EK T L+ N D+
Sbjct: 415 KDKKREKERDHISERRE-RERSTSMRKSSNDRDGKE---KLEKNSTSLKEKEHNKEPDSS 470
Query: 371 TASCEDD 377
+ DD
Sbjct: 471 VSKEVDD 477
Score = 71.6 bits (174), Expect = 4e-12
Identities = 81/355 (22%), Positives = 141/355 (39%), Gaps = 48/355 (13%)
Query: 91 ERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRD 150
E A +E E++ ++ REA+ S + E K + R + ++
Sbjct: 149 EMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS 208
Query: 151 RQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERK--LQYGDSKDNPLKYWLYK 208
R+ +++ + RS ++ RS +KD + + + RER+ S+D
Sbjct: 209 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 268
Query: 209 EEGERRHRKPREPDRD-NKHREKSSTREKREKYSKEKS---NSFSDKGEERHKEKRHKEG 264
+E ER K RE +R+ K REK R K + KE+ +K ER +EK H++
Sbjct: 269 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 328
Query: 265 FHFDDERHQSNVDRKEKSAK---DEPRKRE--------SQNGEHRNRGASSKRDGTSSQH 313
+ E+ Q +EK DE RK++ S N R+R +S +R S+
Sbjct: 329 RDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 388
Query: 314 AENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTAS 373
+ R+ K +RK K D++ EKE + R + S
Sbjct: 389 SS---RSPRTSKTIKRKSSRSPSPRSRNKKDKKR--------EKERDHISERRERERSTS 437
Query: 374 CEDDFEDYEDDFEVCDGDDDESSNEPESREKLEE--LPLAQKKEIQEIQRAINAE 426
+SSN+ + +EKLE+ L +K+ +E +++ E
Sbjct: 438 MR------------------KSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474
Score = 54.3 bits (129), Expect = 6e-07
Identities = 43/198 (21%), Positives = 87/198 (43%), Gaps = 18/198 (9%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E + + K+ + + ++H KE+ K +E++ + E+D K+ + R P
Sbjct: 306 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 365
Query: 62 QDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRG--- 118
+ + ++ S R+R R+R R R + +K K + SR
Sbjct: 366 R---------SYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 416
Query: 119 KDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSV-SKVRSEEKDEDSE 177
K REKE+D + + E ++ + + + + DR E+ E+ S+ K ++E D
Sbjct: 417 KKREKERDHISERRERERSTS----MRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVS 472
Query: 178 RGDEDRER-RYRERKLQY 194
+ +D++ R E K+Q+
Sbjct: 473 KEVDDKDAPRTEENKIQH 490
Score = 50.4 bits (119), Expect = 9e-06
Identities = 84/387 (21%), Positives = 152/387 (39%), Gaps = 71/387 (18%)
Query: 132 EELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSER------GDEDRER 185
+E+R+TV NL Q T QLLE ++ G V VR + R D++
Sbjct: 62 DEIRRTVYVGNLNSQTTTADQLLEFFKQVG-EVKFVRMAGDETQPTRFAFVEFADQNSVP 120
Query: 186 R--------YRERKLQYGDSKD--------NPLKYWLYKEEGERRHRKPREPDRDNKHRE 229
R + +R L+ S + P EE +R R+ + E
Sbjct: 121 RALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPE 180
Query: 230 KSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRK 289
+ E++ S+ + S S + H ++ + H ++S +K++ P K
Sbjct: 181 SGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK 240
Query: 290 RESQNGEHR-NRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPG 348
+ S++ E R +R S RD K KD+R K +E + D+
Sbjct: 241 KRSKSRERRKSRSRSHSRD---------------KRKDTREKIKEKERVK---EKDREKE 282
Query: 349 GEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEEL 408
E E EKE+ +N +D ++ E D E D+ + REK E
Sbjct: 283 REREKEREKEKERGKN----------KDRDKEREKDRE-----KDKEKDREREREKEHEK 327
Query: 409 PLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFEKEPRTDTNSSPSRASVCGIFV 468
++KE ++ + E ER + S ++ +KR + + + P N+S S
Sbjct: 328 DRDKEKEKEQ-----DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRS------ 376
Query: 469 DFASASHRQKSRTQALKQKMRSTKLLR 495
S+ R++ R+++ + R++K ++
Sbjct: 377 ---SSRERRRRRSRSSSRSPRTSKTIK 400
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 98.6 bits (244), Expect = 3e-20
Identities = 63/237 (26%), Positives = 118/237 (49%), Gaps = 14/237 (5%)
Query: 28 GGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRD 87
G + R + K+++ D + + R R+ + R RDR + ++ R+RD
Sbjct: 55 GSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRD 114
Query: 88 RQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQE 147
R+++ + +DRE+EK K + RE ++ R +DR++EK+R + E+ R +
Sbjct: 115 REKQTEIE-RDREREKQKGRERERDRGRERERDRDREKERERQTEKDRD--GQRETETER 171
Query: 148 TRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLY 207
RDR ER ++K R + R ++D + ER + R R+RK Q ++
Sbjct: 172 ERDR---EREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRET------- 221
Query: 208 KEEGERRHRKPREPDRD-NKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKE 263
EGER + RE RD ++ +E+ R+++E+ KE+ + +E+ KE++ +E
Sbjct: 222 DREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRE 278
Score = 89.4 bits (220), Expect = 2e-17
Identities = 62/218 (28%), Positives = 106/218 (48%), Gaps = 15/218 (6%)
Query: 31 KEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRG-----ERD 85
+ ER +K KE + D +E R ++ + + R+RDR + ++ R ER+
Sbjct: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETN-RNRDREKQTEIERDREREKQKGRERE 136
Query: 86 RDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLG 145
RDR RER RD R++EK +E+ E ++ R + E+E+DR K++ R+T +
Sbjct: 137 RDRGRERERD---RDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
Query: 146 QETRDRQLLERAER-KGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKY 204
++R+ ER + R R E D + ER E RR R+R G +D
Sbjct: 194 DTEKERERQTDRERDRQRKTQTERQRETDREGER--ETDRRRERQRDRDRGKERDRERD- 250
Query: 205 WLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSK 242
KEE ++ +K R+ +R K +E+ +K+ K+ +
Sbjct: 251 --RKEERKKERKKERKKERKEKKKEEKRREDKKRKWGE 286
Score = 85.5 bits (210), Expect = 2e-16
Identities = 65/228 (28%), Positives = 111/228 (48%), Gaps = 16/228 (7%)
Query: 70 VAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRA 129
+ + H + +R+RDR RE+ +DR++++ +E+ R+ EK +R +DREK+ +
Sbjct: 65 LGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRK-EKETNRNRDREKQTEIER 123
Query: 130 RKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRE 189
+E +Q G+E + ER + R + R EKD D +R E R RE
Sbjct: 124 DREREKQK-------GRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE 176
Query: 190 RKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNK---HREKSSTRE-KREKYSKEKS 245
R+ Q + + E ER + RE DR K R++ + RE +RE + +
Sbjct: 177 REKQKERETERD-RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRER 235
Query: 246 NSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQ 293
D+G+ER +E+ KE + + + +RKEK K E ++RE +
Sbjct: 236 QRDRDRGKERDRERDRKEE-RKKERKKERKKERKEK--KKEEKRREDK 280
Score = 73.6 bits (179), Expect = 1e-12
Identities = 57/201 (28%), Positives = 101/201 (50%), Gaps = 17/201 (8%)
Query: 7 RTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEP---RCRDPDQD 63
R ++ T K D + + KE ++R+++ + E E D K+ R RD ++
Sbjct: 83 RVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRE 142
Query: 64 A-RSRDRVAEVHTAKESPR-GERDRDRQRERRRDAKDREKEKL----KEKHREAEKSHSR 117
R RDR E E R G+R+ + +RER R+ ++++KE+ +++ R+ EK R
Sbjct: 143 RERDRDREKERERQTEKDRDGQRETETERERDRE-REKQKERETERDRDRQRDTEKERER 201
Query: 118 GKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSE 177
DRE+++ R+ + E R+T + G+ DR+ R ++ R K R E+D E
Sbjct: 202 QTDRERDRQRKTQTERQRET----DREGERETDRR---RERQRDRDRGKERDRERDRKEE 254
Query: 178 RGDEDRERRYRERKLQYGDSK 198
R E ++ R +ERK + + K
Sbjct: 255 RKKERKKERKKERKEKKKEEK 275
Score = 70.5 bits (171), Expect = 8e-12
Identities = 50/233 (21%), Positives = 102/233 (43%), Gaps = 24/233 (10%)
Query: 104 LKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRS 163
L + H++A+ G DR++E+DR K E + RDR+ RK +
Sbjct: 65 LGQAHKDAD-----GDDRQRERDRVREKTEK-----------ERDRDRKRDRERRRKEKE 108
Query: 164 VSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDR 223
++ R EK + ER E +++ RER+ G ++ + E+ + E DR
Sbjct: 109 TNRNRDREKQTEIERDREREKQKGRERERDRGRERER-------DRDREKERERQTEKDR 161
Query: 224 DNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEK-RHKEGFHFDDERHQSNVDRKEKS 282
D + ++ RE+ +++ + D+ +R EK R ++ D + ++ +R+ ++
Sbjct: 162 DGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRET 221
Query: 283 AKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEE 335
++ R+ + + R+R +RD + E + K R++ EE
Sbjct: 222 DREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEE 274
Score = 67.0 bits (162), Expect = 9e-11
Identities = 54/175 (30%), Positives = 90/175 (51%), Gaps = 41/175 (23%)
Query: 28 GGSKEERKHREKKLRKESEMDLPEHKEP---RCRDPDQDARS-----RDRVAEVHTAKES 79
G +E + REK+ +++E D +E R RD +++ + RDR + T KE
Sbjct: 140 GRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKER 199
Query: 80 PRG-ERDRDRQR----ERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEEL 134
R +R+RDRQR ER+R+ DRE E+ ++ RE ++ RGK+R++E+DR+ +++
Sbjct: 200 ERQTDRERDRQRKTQTERQRET-DREGERETDRRRERQRDRDRGKERDRERDRKEERKKE 258
Query: 135 RQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRE 189
R + ERK K R E+K E+ R ED++R++ E
Sbjct: 259 R--------------------KKERK-----KERKEKKKEEKRR--EDKKRKWGE 286
Score = 64.7 bits (156), Expect = 4e-10
Identities = 56/230 (24%), Positives = 107/230 (46%), Gaps = 20/230 (8%)
Query: 144 LGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLK 203
LGQ +D +R + R V + +E+D D +R DRERR +E++ ++ +
Sbjct: 65 LGQAHKDADGDDRQRERDR-VREKTEKERDRDRKR---DRERRRKEKETNRNRDREKQTE 120
Query: 204 YWLYKEEGERRHRKPREPDRD-NKHREKSSTREKREKYSKEKS-----NSFSDKGEERHK 257
+ + ER +K RE +RD + RE+ REK + EK + +++ +R +
Sbjct: 121 I---ERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRER 177
Query: 258 EKRHKEGFHFD-DERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAEN 316
EK+ + D D + + +R+ ++ ++ R+R++Q R +R+ T +
Sbjct: 178 EKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERE-TDRRRERQ 236
Query: 317 LVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENAR 366
R+ GK++D R E K ++ +E E +KEE E+ +
Sbjct: 237 RDRDRGKERDRERDRKEERK-----KERKKERKKERKEKKKEEKRREDKK 281
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 95.9 bits (237), Expect = 2e-19
Identities = 98/447 (21%), Positives = 188/447 (42%), Gaps = 57/447 (12%)
Query: 13 WKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAE 72
W+ + R + SG + E KE++ KE + D + S +R E
Sbjct: 362 WRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNE 421
Query: 73 VHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKE 132
++ + + ++R+ RR+++ +K K K K R KS S+ K++ K K+R ++
Sbjct: 422 ---KEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSK-- 476
Query: 133 ELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKL 192
HN R+ + R+ KGR V+ +EK DS+ D++R R + K
Sbjct: 477 --------HN------RNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSR--SKEKS 520
Query: 193 QYGDSKDNPLKYWLYKEEGERRHRKPREPD-RDNKHREKSSTREKREKYSKEKSNSFSDK 251
+ +SK N + KE+ R + RE D KH S TRE+ S+++S +
Sbjct: 521 KQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSR--SRDRSRRVRSR 578
Query: 252 GEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSS 311
+R + R KE + ++ ++ + + + P + S++ R +RD SS
Sbjct: 579 THDRDR-SRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRR------RRDSRSS 631
Query: 312 QHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYT 371
+ E+ RN K ++ K H +E E EK Y+
Sbjct: 632 EREESQSRNKDKYRNQESKSSHR---------------KENSESEKR----------MYS 666
Query: 372 ASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERI- 430
S + + + + + S + S++ + + + KE ++I+ ++ EN++
Sbjct: 667 KSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSK 726
Query: 431 GELSLKLFQKRGRTEFEKEPRTDTNSS 457
G+ + + +K + + E P TD + S
Sbjct: 727 GQENDHVHEKNKKFDHESSPGTDEDKS 753
Score = 73.6 bits (179), Expect = 1e-12
Identities = 92/465 (19%), Positives = 180/465 (38%), Gaps = 67/465 (14%)
Query: 38 EKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAK 97
+ K++KE + D D+ S + + + ES E+ + R+++ R++++
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239
Query: 98 DREKEKLKEK--------HREAE--------------------------KSHSRGKDREK 123
+KEK K K EAE KS + ++E+
Sbjct: 240 KHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKER 299
Query: 124 EKDRRARKEELR----QTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERG 179
+ R R+ E Q ++ L R++ R R+ R+ S+ RS ++ SE
Sbjct: 300 KNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETP 359
Query: 180 DEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREK 239
R+ R ++++ GER + + + K ++S R K K
Sbjct: 360 PHWRQEMQRAQRMRV--------------SSGERWIKGDKSELNEIKENQRSPVRVKERK 405
Query: 240 YSKEK--SNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEH 297
+ + S S + K E+ K K HK D R S D K K+ K + R + +
Sbjct: 406 ITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKN-KVKKRAKSKSRSKS 464
Query: 298 RNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEK 357
+ + S +RD +++ E +R+ K +D HE + D + +E ++
Sbjct: 465 KEKSKSKERDSKHNRNEEKRMRSRSKGRD------HENVKEKEKQSDSKGKDQERSRSKE 518
Query: 358 EETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQ--KKE 415
+ LE+ + + ++ + CD + S +RE+ ++ +
Sbjct: 519 KSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSR 578
Query: 416 IQEIQRAINAENERIGELSLKLFQKRGRTEFEKEPRTDTNSSPSR 460
+ R+ + E R E + +++RGR+ +E RT S S+
Sbjct: 579 THDRDRSRSKEYHRYRE---QEYRRRGRSR-SRERRTPPGRSRSK 619
Score = 36.2 bits (82), Expect = 0.17
Identities = 29/128 (22%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 3 PGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKE-PRCRDPD 61
PG+ R+KD + D R +K++ +++E K E E + + RD +
Sbjct: 613 PGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHN 672
Query: 62 QDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEK-HREAEKSHSRGKD 120
SR++ A+ + S + +D + + K++E EK++ +E +KS + D
Sbjct: 673 SSNNSREKKADRDQSPFSKIKQSSQDNELKSSM-LKNKEDEKIRSSVEKENQKSKGQEND 731
Query: 121 REKEKDRR 128
EK+++
Sbjct: 732 HVHEKNKK 739
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 94.4 bits (233), Expect = 5e-19
Identities = 115/527 (21%), Positives = 225/527 (42%), Gaps = 87/527 (16%)
Query: 5 KRRTKDDTWKADDLRKHL-WAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQD 63
+RR + W+ ++ RK + + + +E+ +E++L +E E +L + + R +Q+
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 64 ARSRDRVAEVHTAKESPRGER------DRDRQ----------------------RERRRD 95
+ R+ ++ R ER +R+RQ R + R+
Sbjct: 928 RQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
Query: 96 AKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLE 155
K RE+E+L+++ + + + R++ + + +K+EL+Q LL +E R+L E
Sbjct: 988 KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ--EEEQLLREEREKRRLQE 1045
Query: 156 RAERKGRSVSKVRSEEK----DEDSERGDEDRERRYR-ERKLQYGDSKDNPLKYWLYKEE 210
R ER+ R +++ EE+ +E R ++ ER+YR E +LQ + + L +EE
Sbjct: 1046 R-ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQ-------LLREE 1097
Query: 211 GERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDE 270
E+R R+ +R+ + RE+ +++ E+ +E+ +EKR ++
Sbjct: 1098 PEKRRRQ----ERERQCREEEELQQEEEQLLREE------------REKRRRQELERQYR 1141
Query: 271 RHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRK 330
+ +E+ ++EP KR Q E + R + Q E L+R + + R+
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYR-----EEEELQQEEEQLLREEQEKRRQERE 1196
Query: 331 HGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEV-CD 389
+ E + QR ++ E + +DL+ E + E+ D +V C
Sbjct: 1197 RQYREEEEL-----QRQKRKQRYRDEDQRSDLK--------WQWEPEKENAVRDNKVYCK 1243
Query: 390 GDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGR--TEFE 447
G E E +LE+ L ++ Q++Q + + ER E + +Q+R R E E
Sbjct: 1244 G------RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE 1297
Query: 448 KEPRTDTNSSPSRASVCGIFVDFASASHRQKSRTQALKQKMRSTKLL 494
+ R + + R +K R Q +K R + L
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQL 1344
Score = 93.6 bits (231), Expect = 9e-19
Identities = 100/481 (20%), Positives = 202/481 (41%), Gaps = 52/481 (10%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEM-----DLPEHKEPR 56
EPG+RR + K + + L + K+ER + + R++ E+ + E +E R
Sbjct: 132 EPGQRRRQ----KRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERR 187
Query: 57 CRDPDQDARSRDRVAEVHTAKESPRGE------RDRDRQRERRRDAKDR------EKE-- 102
+ + E ++ R E + R+ ++++RR+ +DR EKE
Sbjct: 188 AEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWR 247
Query: 103 -------KLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLE 155
K +EK +E E R E+E+ R+ ++ELR+ Q R Q L
Sbjct: 248 KRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLR 307
Query: 156 RAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRH 215
R + + R + + EE+ E ER ++ ERR ++ + + + ++ L+ +E+ E R
Sbjct: 308 RKQEEER---REQQEERREQQERREQQEERREQQLRREQEERREQQLR----REQEEERR 360
Query: 216 RKPREPDRDNKHREKSSTRE---KREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERH 272
+ +++ + RE+ RE +RE+ + + ++ R ++ R ++ + +
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 273 QSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHG 332
+ R+E+ + +K E + E R + +R + E + K ++
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 333 HEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDD 392
EE W KL++ E + E+ E L + + + E+ E + +
Sbjct: 481 EEERRERWLKLEEE---ERREQQERREQQLRREQEERREQRLKRQ-EEEERLQQRLRSEQ 536
Query: 393 DESSNEPESREKL----EELPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFEK 448
+ E RE+L EE L Q++ Q ++R E E + LK ++R + ++
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKR----EQEERRDQLLKREEERRQQRLKR 592
Query: 449 E 449
E
Sbjct: 593 E 593
Score = 92.4 bits (228), Expect = 2e-18
Identities = 97/436 (22%), Positives = 188/436 (43%), Gaps = 37/436 (8%)
Query: 31 KEERKHREKKLRKESEMDLPEHK-EPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQ 89
+E++ RE++LR+E E + E K E R+ +R + +E+ R E++R R+
Sbjct: 415 REQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER-RK 473
Query: 90 RERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETR 149
++ +RD ++ +E+ + E + ++++ +++ R+E+ + L Q R
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 150 DRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKE 209
Q L R + + R R EEK + ER ++ +R ER+ Q ++ + L +E
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Query: 210 EGER-RHRKPREPDRDNKHREKSSTREKREKYSKEKSNSF--SDKGEERHKEKRHKEGFH 266
+ ER R RE + E+ R KRE+ +E+ S++ EER +++ +E
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE--- 650
Query: 267 FDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKD 326
ER + + R+E+ + E R + E R + + + + + ++ + +
Sbjct: 651 -QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLE 709
Query: 327 SRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENAR------ADAYTASCEDDFED 380
S E + K+ RP +E +E+ + R + A + E+
Sbjct: 710 S-------EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
Query: 381 YEDDF-------EVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGEL 433
DF E + S P RE+ E A++++ +E QR + E E
Sbjct: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE-QRFLPEEEE----- 816
Query: 434 SLKLFQKRGRTEFEKE 449
K ++R R E EKE
Sbjct: 817 --KEQRRRQRREREKE 830
Score = 90.9 bits (224), Expect = 6e-18
Identities = 105/480 (21%), Positives = 210/480 (43%), Gaps = 48/480 (10%)
Query: 26 QSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERD 85
Q KE RK RE LRKE E + +EP+ R R+ E ++ R E
Sbjct: 239 QEEEEKEWRK-RETVLRKEEEK--LQEEEPQ--------RQRELQEEEEQLRKLERQELR 287
Query: 86 RDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLG 145
R+RQ E ++ + R +++L+ K E + ++R ++++RR ++EE R+
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQ--EERREQQERREQQEERREQQLRRE--- 342
Query: 146 QETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDS-------- 197
QE R Q L R + + R ++R E+++E E+ ++ RE++L+
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 198 KDNPLK--YWLYKEEGERRHRKPREPDRDNKHREK--SSTREKREKYSKEKSNSFSDKGE 253
++ L+ L +E+ RR ++ R + +H +K RE+R K +E+ + + E
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462
Query: 254 E--RHKEKRHKEGFHFDDERHQS----NVDRKEKSAKDEPRKRESQNGEHRNRGASSKRD 307
E RH+++R K+ D E + ++ +E+ + E R+++ + + R KR
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR- 521
Query: 308 GTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARA 367
+ E L + ++ RR+ EE K ++ E+ +E E+ E L+ +
Sbjct: 522 ---QEEEERLQQRLRSEQQLRRE--QEERREQLLKREE----EKRLEQERREQRLKREQE 572
Query: 368 DAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAEN 427
+ + + E + + + +E + RE++E L +++E Q ++R E
Sbjct: 573 ERRDQLLKREEERRQQRLK---REQEERLEQRLKREEVERLEQEERRE-QRLKREEPEEE 628
Query: 428 ERIGELSLKLFQKRGRTEFEKEPRTDTNSSPSRASVCGIFVDFASASHRQKSRTQALKQK 487
R L + ++R + + +E + R H ++ R Q L ++
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE 688
Score = 90.5 bits (223), Expect = 8e-18
Identities = 102/484 (21%), Positives = 219/484 (45%), Gaps = 68/484 (14%)
Query: 29 GSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRD- 87
G + ++ EK+ R+ESE+ E + + +++ R RD + ++S RG +
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR-RDFTWQWQAEEKSERGRQRLSA 786
Query: 88 -----RQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKD-----------RRARK 131
QRER+ A++R++ + + E EK R + RE+EK+ RR R
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERA 846
Query: 132 EELR------QTVAHHNLLGQETRDR----QLLERAERKGRSV-------SKVRSEEK-- 172
++L+ Q ++ RD+ QL E +R+ ++ ++R E++
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
Query: 173 -DEDSERGDEDRERRYR-ERKLQYGDSKD-NPLKYWLYKEEGERRHRKPREPDRDNKHRE 229
+E+ E E+RE+R R E++ QY + + + L +EE E+R R+ +R+ ++R+
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ----ERERQYRK 962
Query: 230 KSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRK 289
++K E+ E+ +K + +EK+++E E Q + +EK + E +
Sbjct: 963 DKKLQQKEEQLLGEE----PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWER 1018
Query: 290 RESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKH----GHEEGSSVWWKLDQ 345
+ + E + R+ + + R + ++++ +++ G E + +L++
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 346 RPGGEETVEIEKEE---TDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESR 402
+ EE ++ E+E+ + E R C ++ E +++ ++ + ++ + R
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138
Query: 403 EKLEELPLAQ-----------KKEIQEIQRAINAENE--RIGELSLKLFQKRGRTEFEKE 449
+ EE + Q K+ QE++R E E + E L+ Q++ R E E++
Sbjct: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ 1198
Query: 450 PRTD 453
R +
Sbjct: 1199 YREE 1202
Score = 89.4 bits (220), Expect = 2e-17
Identities = 106/546 (19%), Positives = 226/546 (41%), Gaps = 62/546 (11%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E K++ K D + ++ R+ ++ +E+++ RE++LR+E E E +E R + +
Sbjct: 470 ERRKQQLKRD--QEEERRERWLKLEEEERREQQERREQQLRREQE----ERREQRLKRQE 523
Query: 62 QDARSRDRVAEVHTAKESPRGERDR--DRQRERRRDAKDREKEKLKEKHREAEKSHSRGK 119
++ R + R+ + R++ R+ E+R + + RE+ +E+ ++ R +
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREE 583
Query: 120 DREKEKDRRARKEELRQTVAHHNL--LGQETRDRQLLERAE-RKGRSVSKVRSEEKDEDS 176
+R +++ +R ++E L Q + + L QE R Q L+R E + R ++SEE++E
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERR 643
Query: 177 ERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTR-- 234
++ ++ RE++L+ + ++ L+ L +E E R + + + RE+ +R
Sbjct: 644 QQQLRREQQERREQRLKREEEEER-LEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
Query: 235 --------EKREKYSKEKSNSFSDKGEERHKE-----KRHKEGFHFDDERHQSNVDRKEK 281
E + SK S +G+ R +E +R + + +E ++E+
Sbjct: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
Query: 282 SAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWW 341
+D + +++ R R S R Q L + ++ R EE
Sbjct: 763 QRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQ--- 819
Query: 342 KLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSN---- 397
+ QR E+ ++ +EE L+ ED ++ ++ + D+
Sbjct: 820 RRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLE 879
Query: 398 ------------EPESREKLEELPLAQKKEIQEIQRAINA------------ENERIGEL 433
+P +E+L + ++E +E+QR E E++ +
Sbjct: 880 EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQE 939
Query: 434 SLKLF----QKRGRTEFEKEPRTDTNSSPSRASVCGIFVDFASASHRQKSRTQALKQKMR 489
+L +KR R E E++ R D + G + R+K + + +
Sbjct: 940 EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQE 999
Query: 490 STKLLR 495
+LLR
Sbjct: 1000 EEQLLR 1005
Score = 88.6 bits (218), Expect = 3e-17
Identities = 98/444 (22%), Positives = 193/444 (43%), Gaps = 39/444 (8%)
Query: 31 KEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQR 90
+E+ + RE++LR+E E + E + R ++ ++ + R ++ ++ R ++ R Q+
Sbjct: 341 REQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ 400
Query: 91 ERRRDAKDREKEKLKEKHREAEKSHSRGKDREK-----EKDRRARKEELRQTVAHHNLLG 145
RR RE++ +E+ E+ R ++ E+ E++RR ++ + Q L
Sbjct: 401 LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKR 460
Query: 146 QETRDRQLLER----------AERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQ-- 193
+E +R ER ER+ R + K+ EE+ E ER ++ R ER+ Q
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWL-KLEEEERREQQERREQQLRREQEERREQRL 519
Query: 194 YGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGE 253
++ L+ L E+ RR ++ R + EK +E+RE+ K + D+
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 254 ERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRES----QNGEHRNRGASSKRDGT 309
+R +E+R + +ER + + R+E ++ +RE + E R K +
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 310 SSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADA 369
+ + L R + ++ R K EE +L+QR E E E+ E +L +
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEE-----RLEQRLKREH--EEERREQELAEEEQEQ 692
Query: 370 YTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENER 429
+ ++ E + D ++ SR + +E ++++ QE +R R
Sbjct: 693 ARERIKSRIPKWQWQLE---SEADARQSKVYSRPRKQE--GQRRRQEQEEKR-----RRR 742
Query: 430 IGELSLKLFQKRGRTEFEKEPRTD 453
EL + ++ R + E+E R D
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRD 766
Score = 88.6 bits (218), Expect = 3e-17
Identities = 95/468 (20%), Positives = 207/468 (44%), Gaps = 43/468 (9%)
Query: 11 DTWKADDLRKHLWAIQSGGSKEERKH---REKKLRKESEMDLPEHKEPRCRDPDQDARSR 67
D DL+ L Q ++ER+ R++ +E +++ E KE + RD +S+
Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD----RKSQ 1315
Query: 68 DRVAEVHTAKESPRGERDRDRQ-RERRRDAKDREKEKLKE-----KHREAEKSHS-RGKD 120
+ + +E R ++ DR+ RE + ++RE++ L+ K RE E H +G+
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375
Query: 121 REKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEE------KDE 174
+E+ R R+E R+ + L + R++QL + +RK R + S + ++E
Sbjct: 1376 FLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREE 1435
Query: 175 DSERGDEDRERRYRERKLQYGDSKDNPLK---YWLYKEEGERRHRKPR-----EPDRDNK 226
+ + ++RER++ E + Q + + L + E ++ HR+ R E ++ +
Sbjct: 1436 EQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLR 1495
Query: 227 HREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFD-----DERHQSNVDRKEK 281
+E+ ++E S+E F ++ ++ H+++R ++ + ER Q +++
Sbjct: 1496 RQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
Query: 282 SAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWW 341
++E + R+ + + +R ++ Q + +D ++ E +
Sbjct: 1556 KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ 1615
Query: 342 KLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPES 401
+ D++ +E + E+EE L E D + E++ ++ + ++
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQ---------ERDRKFLEEEPQLRRQEREQQLRHDRD 1666
Query: 402 REKLEELPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFEKE 449
R+ EE L Q+ E Q+++R R E L+ Q+R R ++E
Sbjct: 1667 RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR-QERERKFLQEE 1713
Score = 85.1 bits (209), Expect = 3e-16
Identities = 100/467 (21%), Positives = 211/467 (45%), Gaps = 80/467 (17%)
Query: 31 KEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDR-- 88
++E K R++K ++E ++ L E +E + R + D + R+ + +E P ++RDR
Sbjct: 1304 QKEAKRRDRKSQEEKQL-LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362
Query: 89 ---------------QRERRRDAKDREKEKLKEKHR----EAEKSHSRGKDRE------- 122
+ E+R ++RE++ LKE+ + E E+ + +DR+
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
Query: 123 ---KEKDRRARKEE--LRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEK----- 172
+E+DR+ R+EE +R+ L +E + RQ R R+ + + R E++
Sbjct: 1423 LSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482
Query: 173 ------DEDSERGDEDRERRYRERKLQYGDSKDNPL------------KYWLYKEEGERR 214
+E+ + ++R+R++RE++L+ + + L + +L +E+ RR
Sbjct: 1483 RDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR 1542
Query: 215 HRK--PREPDRDNKHREKSSTREKREKYS---KEKSNSFSDKGEERHKEKRHKEGFHFDD 269
+ R DRD K RE+ R++RE+ +E+ F + EE+ ++ +E +D
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF--RLEEQKVRRQEQERKFMED 1600
Query: 270 E--------RHQSNVDRKEKSAKDE----PRKRESQNGEHRNRGASSKRDGTSSQHAENL 317
E + Q +R K +DE R+ + + + R+R + Q E
Sbjct: 1601 EQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ 1660
Query: 318 VRNHGKDKDSRRKHG-HEEGSSVWWKLDQRPG--GEETVEIEKEETDLENARADAYTASC 374
+R H +D+ R + +EG + +R EE ++ ++E + + + +
Sbjct: 1661 LR-HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQ 1719
Query: 375 EDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQR 421
E + + E++ + + ++ + R+ LEE L ++E Q+++R
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766
Score = 84.3 bits (207), Expect = 5e-16
Identities = 112/499 (22%), Positives = 215/499 (43%), Gaps = 93/499 (18%)
Query: 31 KEERKHREKKLRKESE------------------MDLPEHKEPRCRDPDQDAR-SRDRVA 71
+ +RK RE++LR + + L E ++ RC++ +Q R RDR
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF 1416
Query: 72 EVHTAKESPRGERDRD--------RQRERRRDAKDREKEKLKEKH------------REA 111
++ R ERDR R++ER R + E++ +E+H RE
Sbjct: 1417 R-EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE 1475
Query: 112 EKSHSRGKDRE----------KEKDRRARKEELRQTVAHHNLLGQE------------TR 149
++ H + +DR+ +E+DR+ R++ELR L +E +
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ 1535
Query: 150 DRQLLERAE----------RKGRSVSKVRSEEKDEDSERGDEDRERRYRERKL--QYGDS 197
+ Q L R E RK R ++R E +++ R + DR+ R E+K+ Q +
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595
Query: 198 KDNPLKYWLYKEEGERRHRKPREPDRDNKHREKS---STREKREKYSKEKSNSFSDKGEE 254
K + L ++EG+++ R+ +RD K RE RE+++ + +E+ F ++ +
Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQ----ERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQ 1651
Query: 255 RHKEKRHKEGFHFDD----ERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTS 310
+++R ++ H D E Q + +E+ + + R R+ + E + R +R+
Sbjct: 1652 LRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLR--RQERERKF 1709
Query: 311 SQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAY 370
Q + L R ++ RK EE + +Q E +I +EE L R +
Sbjct: 1710 LQEEQQLRR-----QELERKFREEEQLRQETEQEQLRRQERYRKILEEE-QLRPEREEQQ 1763
Query: 371 TASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERI 430
E D + E++ + ++ + ++ R+ EE L Q++E Q+++ R
Sbjct: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRW 1823
Query: 431 GELSLKLFQKRGRTEFEKE 449
E L+L ++ R E++
Sbjct: 1824 EEEQLQLEEQEQRLRQERD 1842
Score = 82.4 bits (202), Expect = 2e-15
Identities = 111/521 (21%), Positives = 222/521 (42%), Gaps = 90/521 (17%)
Query: 31 KEERKHREKKLRKESEMDL------PEHKEPR-----CRDPDQDARSR------------ 67
+E+++ RE++L++E E + EH+E R + + AR R
Sbjct: 649 REQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL 708
Query: 68 -----DRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDRE 122
R ++V++ G+R R Q E+RR RE E + +E E++H + ++ E
Sbjct: 709 ESEADARQSKVYSRPRKQEGQRRRQEQEEKRR---RRESEL---QWQEEERAHRQQQEEE 762
Query: 123 KEKD------RRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDS 176
+ +D + E RQ ++ L +E R+RQL RAE + + + EE++++
Sbjct: 763 QRRDFTWQWQAEEKSERGRQRLSARPPL-REQRERQL--RAEERQQREQRFLPEEEEKEQ 819
Query: 177 ERGDEDRERRYRERKLQYGDSKDNPLK----YWLYKEEG----ERRHRKPREPDRDNKHR 228
R R+RR RE++LQ+ + ++ + L +EE ++ R+ +E RD K R
Sbjct: 820 RR----RQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875
Query: 229 EKSSTREKREKYS-----------KEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVD 277
+ KR +++ +++ ++ EE +E+R K ++ Q +
Sbjct: 876 WQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR--RRQEQERQYREE 933
Query: 278 RKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGS 337
+ + +++ + E + + R ++D Q E L+ G++ + RR+ E+
Sbjct: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL---GEEPEKRRRQEREKKY 990
Query: 338 SVWWKLDQRPG---GEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDE 394
+L Q EE + ++E + + + D E + + + + +
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL--QERER 1048
Query: 395 SSNEPESREKLEELPLAQKKEI---QEIQRAINAENERIGE---LSLKLFQKRGRTEFEK 448
E E ++ EE L +++E QE++R E E E L + +KR R E E+
Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Query: 449 EPRTDTNSSPSRASVCGIFVDFASASHRQKSRTQALKQKMR 489
+ R + + R+K R Q L+++ R
Sbjct: 1109 QCREEEELQQEEEQLL--------REEREKRRRQELERQYR 1141
Score = 81.6 bits (200), Expect = 4e-15
Identities = 91/457 (19%), Positives = 196/457 (42%), Gaps = 73/457 (15%)
Query: 31 KEERKHREKKLRK----ESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDR 86
+E++ HR+++ RK E ++ E + R +D D+ R +++ + ++ R ERDR
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDR 1579
Query: 87 DRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQ 146
+ E ++ + ++ K E ++ + + + R+ E+DR+ R++E L +
Sbjct: 1580 KFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ-ERDRKFREDEQLLQEREEQQLHR 1638
Query: 147 ETRDRQLLERA----------------ERKGRSVSKVRSEEKDEDSERGDEDRERRYRER 190
+ RDR+ LE +RK R ++ E +++ R + DR+ R E+
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698
Query: 191 KLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSD 250
+L+ + + + +L +E+ RR + + K RE+ R++ E+
Sbjct: 1699 QLRRQERE----RKFLQEEQQLRRQ------ELERKFREEEQLRQETEQ----------- 1737
Query: 251 KGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTS 310
E+ +++R+++ + R + + + +D + E Q + R ++
Sbjct: 1738 --EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDR 1795
Query: 311 SQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAY 370
E +R +++ R + +G W EE +++E++E L R Y
Sbjct: 1796 KFREEEQLRQEREEQQLRPQ--QRDGKYRW--------EEEQLQLEEQEQRLRQERDRQY 1845
Query: 371 TASCEDDFEDYE----DDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAE 426
A E+ F E ++ E+ ++ + E E + + E + QK+E
Sbjct: 1846 RA--EEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEE---------QR 1894
Query: 427 NERIGELSLKLFQKRGRTEFEKEPRTDTNSS-PSRAS 462
+ ++GE+ + + GR EP T +S P R+S
Sbjct: 1895 HRQVGEIKSQEGKGHGRL---LEPGTHQFASVPVRSS 1928
Score = 80.9 bits (198), Expect = 6e-15
Identities = 64/301 (21%), Positives = 151/301 (50%), Gaps = 24/301 (7%)
Query: 29 GSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESP--RGERDR 86
G ++ R+ R++K R++ ++ L E +E + ++D + + ++ + R +RDR
Sbjct: 1609 GQQQLRQERDRKFREDEQL-LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDR 1667
Query: 87 DRQRERRRDAKDREKEKLKEKHRE----AEKSHSRGKDREK---EKDRRARKEELRQTVA 139
+ RE + ++ E+++L+ + R+ E+ R ++RE+ +++++ R++EL +
Sbjct: 1668 -KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR 1726
Query: 140 HHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKD 199
L QET Q L R ER + + + + + E+ + ++R+R++RE + + ++
Sbjct: 1727 EEEQLRQETEQEQ-LRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785
Query: 200 NPLKYW----LYKEE----GERRHRKPREPDRDNKHR---EKSSTREKREKYSKEKSNSF 248
L+ ++EE ER ++ R RD K+R E+ E+ ++ +E+ +
Sbjct: 1786 QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQY 1845
Query: 249 SDKGEERHKEK-RHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRD 307
+ + +EK R +E + +E + +R+ K ++ R+++ + HR G ++
Sbjct: 1846 RAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905
Query: 308 G 308
G
Sbjct: 1906 G 1906
Score = 79.3 bits (194), Expect = 2e-14
Identities = 99/494 (20%), Positives = 207/494 (41%), Gaps = 74/494 (14%)
Query: 26 QSGGSKEERKHR----EKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPR 81
Q+ G EE++ R E L+ + + EPR R +++ R R +E
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Query: 82 GERD---------RDRQRE------RRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKD 126
GE RDRQR +R++ ++RE+ + +E+ ++ K H + ++E+
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
Query: 127 RR---------ARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSE 177
RR R+E+ +Q + + QE +++ +R + K++ EE E
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 178 RGDEDRERRYRER-KLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTRE- 235
+E+ + R ER +L+ ++ + L +E+ RR ++ ++ + RE+ RE
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
Query: 236 ---------KREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDE 286
+RE+ + + ++ EER +++ +E ++ER + + R+++ +++
Sbjct: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLRREQ---EEERREQQLRREQQLRREQ 387
Query: 287 PRKRESQ----------------NGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRK 330
+RE Q R + ++ Q E + H +++ +R
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 331 HGHEEGSSVWWKLDQRPGGEETVEIEKE------ETDLENARADAYTASCEDDFEDYEDD 384
+E W K + EET E+E + D E R + + E++ + ++
Sbjct: 448 KREQEERRDWLKRE-----EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQER 502
Query: 385 FEVCDGDDDESSNEPESREKLEELPLAQK-KEIQEIQRAINAENERI----GELSLKLFQ 439
E + E E + + EE L Q+ + Q+++R E++ E L+ +
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 440 KRGRTEFEKEPRTD 453
+ R + E+E R D
Sbjct: 563 REQRLKREQEERRD 576
Score = 69.7 bits (169), Expect = 1e-11
Identities = 101/423 (23%), Positives = 177/423 (41%), Gaps = 75/423 (17%)
Query: 32 EERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGER-DRDRQR 90
E+R+ +E + + E +L + +E R+ +Q+ R ++R + +E R +R R R
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLRE-EQEKRRQERERQYREEEELQRQKRKQRYRDE 1217
Query: 91 ERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEK---DRRARKEELRQTVAHHNLLG-Q 146
++R D K + E KE K + +G++ E+ + D + R + +Q + H LLG Q
Sbjct: 1218 DQRSDLK-WQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH--LLGEQ 1274
Query: 147 ETRDRQLL--------------ERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKL 192
+ RDR+ E+ ER+ + +K R + E+ + E+RE + R+
Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEK---RRR 1331
Query: 193 QYGDSKDNPLKYWLYKEE----GERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSF 248
Q D K ++EE ER + R +RD K RE+
Sbjct: 1332 QETDRK--------FREEEQLLQEREEQPLRRQERDRKFREE------------------ 1365
Query: 249 SDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEP----RKRESQNGEHRNRGASS 304
E RH+E+ K ++E+ +R+ K K+E ++RE Q + R+R
Sbjct: 1366 ----ELRHQEQGRK---FLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE 1418
Query: 305 KRDGTSSQHAENLVRNHGKD--KDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDL 362
+ S Q + R + + R + EE + + ++ EE + E+EE L
Sbjct: 1419 EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL 1478
Query: 363 ENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPL----AQKKEIQE 418
D E E D + + + S EPE + EE L Q+K +QE
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKF--REQELRSQEPERKFLEEEQQLHRQQRQRKFLQE 1536
Query: 419 IQR 421
Q+
Sbjct: 1537 EQQ 1539
Score = 45.1 bits (105), Expect = 4e-04
Identities = 36/159 (22%), Positives = 76/159 (47%), Gaps = 17/159 (10%)
Query: 5 KRRTKDDTWKADD-LRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQD 63
+R+ +D ++ ++ LR+ Q + +RK RE++ ++ E +E + R +D
Sbjct: 1765 RRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ------EREEQQLRPQQRD 1818
Query: 64 ARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREK 123
+ R ++ ++ R ++RDRQ +EK + +E+ E+ R ++RE
Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE- 1877
Query: 124 EKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGR 162
R+ R+E +R+ +E R RQ+ E ++G+
Sbjct: 1878 ---RKLREEHIRRQQK------EEQRHRQVGEIKSQEGK 1907
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 90.9 bits (224), Expect = 6e-18
Identities = 61/225 (27%), Positives = 113/225 (50%), Gaps = 32/225 (14%)
Query: 65 RSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKE 124
R R+R E KE+ ER+RDRQRER + + + +++HRE ++ R K+RE++
Sbjct: 3 RQRERKRETDRGKET---ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
Query: 125 KDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRE 184
K+R +++ R+T + R R+ + ERK ++ E+D+D +R +
Sbjct: 60 KERDRQRQRERETER------ETERQRERQRQRERKRQT-----DRERDKDRDRERKRET 108
Query: 185 RRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEK 244
R RER + G +D K + + ER ++ RE +R + K T +R++++ E+
Sbjct: 109 DRNRERNRKGGRERD---KQTERERDRERERQRQRERERQRQRERKRETDRERQRWA-ER 164
Query: 245 SNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRK 289
++ +ER KE++ K+ ++EK +D+ RK
Sbjct: 165 EERKKERKKERKKERKEKK--------------KEEKRREDKKRK 195
Score = 89.4 bits (220), Expect = 2e-17
Identities = 63/202 (31%), Positives = 100/202 (49%), Gaps = 15/202 (7%)
Query: 51 EHKEPRCRDPD---QDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEK 107
E + R R+ D + R RDR E E R RDR RER R DREKE+ ++K
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQT-DREKERERQK 60
Query: 108 HREAEKSHSRGKDR--EKEKDRRARKEELRQTVAHHNLLGQETRDRQL---LERAERKGR 162
R+ ++ R +R E++++R+ ++E RQT + R R+ ER + GR
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
Query: 163 SVSKVRSEEKDEDSER-GDEDRER-RYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPRE 220
K E+D + ER +RER R RERK + D + W +EE ++ +K R+
Sbjct: 121 ERDKQTERERDRERERQRQRERERQRQRERKRE----TDRERQRWAEREERKKERKKERK 176
Query: 221 PDRDNKHREKSSTREKREKYSK 242
+R K +E+ +K+ K+ +
Sbjct: 177 KERKEKKKEEKRREDKKRKWGE 198
Score = 80.1 bits (196), Expect = 1e-14
Identities = 51/198 (25%), Positives = 95/198 (47%), Gaps = 11/198 (5%)
Query: 5 KRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDA 64
+R+ + D K + + + ++ E +HR++ +E + KE Q
Sbjct: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERE----RQKE 61
Query: 65 RSRDRVAEVHTAKESPRGERDRDRQRERRRDA-----KDREKEKLKEKHREAEKSHSRGK 119
R R R E T +E+ R +R+R RQRER+R KDR++E+ +E R E++ G+
Sbjct: 62 RDRQRQRERETERETER-QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
Query: 120 DREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERG 179
+R+K+ +R +E RQ Q R R+ +R + + +K+ ER
Sbjct: 121 ERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
Query: 180 DEDRERRYRE-RKLQYGD 196
++ +E + RE +K ++G+
Sbjct: 181 EKKKEEKRREDKKRKWGE 198
Score = 63.9 bits (154), Expect = 8e-10
Identities = 51/228 (22%), Positives = 94/228 (41%), Gaps = 33/228 (14%)
Query: 106 EKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVS 165
E+ RE ++ RGK+ E+E+DR+ +E + ER+ R
Sbjct: 2 ERQRERKRETDRGKETERERDRQREREN----------------------QTERENRHRQ 39
Query: 166 KVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKE-EGERRHRKPREPDRD 224
+ R E+D ++R E ++ R+R+ Q + + ++ + ER+ + RE D+D
Sbjct: 40 RDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKD 99
Query: 225 NKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAK 284
K T RE+ K DK ER +++ + + ER + R+ K
Sbjct: 100 RDRERKRETDRNRER--NRKGGRERDKQTERERDRERERQRQRERERQR---QRERKRET 154
Query: 285 DEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHG 332
D R+R ++ E + ++ + E R +D +RK G
Sbjct: 155 DRERQRWAEREERKKERKKERKKERKEKKKEEKRR-----EDKKRKWG 197
Score = 45.1 bits (105), Expect = 4e-04
Identities = 48/208 (23%), Positives = 79/208 (37%), Gaps = 29/208 (13%)
Query: 212 ERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKE-KRHKEGFHFDDE 270
ER+ + RE DR K E+ R++ + E+ N RH++ RH+E D
Sbjct: 2 ERQRERKRETDR-GKETERERDRQRERENQTEREN--------RHRQRDRHRE----RDR 48
Query: 271 RHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRK 330
+ +R+ + +D R+RE + R +R + + R KD+D RK
Sbjct: 49 QTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTD---RERDKDRDRERK 105
Query: 331 HGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDG 390
+ + R GG E + + E D E R + E +
Sbjct: 106 RETDRN-----RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRE------- 153
Query: 391 DDDESSNEPESREKLEELPLAQKKEIQE 418
D E E E+ +E +KKE +E
Sbjct: 154 TDRERQRWAEREERKKERKKERKKERKE 181
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 89.0 bits (219), Expect = 2e-17
Identities = 61/200 (30%), Positives = 106/200 (53%), Gaps = 15/200 (7%)
Query: 66 SRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDRE-KE 124
S +++ T +ES R + R+R++ +R K+R++E+ K K ++ K RGK+RE K
Sbjct: 21 SCSHISKPCTQRESERKKERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKR 79
Query: 125 KDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRE 184
K+R +++E R+ ++ R+R+ R ERK +K E ER E+++
Sbjct: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERK----------KKKERKERERENKQ 129
Query: 185 RRYRERKLQYGDSKDNPLKYWLYKEEGER-RHRKPREPDRDNKHREKSSTREKREKYSKE 243
RR R+RK + + K KE G+R R RK R+ + K RE++ K+E+ KE
Sbjct: 130 RRERKRKKRRKKKRRKERKR--EKERGKRERKRKKRKKEEREKKRERNRKERKKERERKE 187
Query: 244 KSNSFSDKGEERHKEKRHKE 263
+ ++ +ER K+K K+
Sbjct: 188 RRERKKERKKERRKKKERKK 207
Score = 82.4 bits (202), Expect = 2e-15
Identities = 62/218 (28%), Positives = 112/218 (51%), Gaps = 34/218 (15%)
Query: 31 KEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQR 90
K+ER+ REK+ R+ + E K R + + + R+R KE R ++R++QR
Sbjct: 37 KKERREREKRKREREK----ERKRERGKKEKKKRKKRER------GKERERKRKEREKQR 86
Query: 91 ERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRD 150
+ RR+ K+R K K KEK + K R ++R+K+K+R+ R+ E +
Sbjct: 87 KERRE-KERRKRK-KEKKKRERKQRGR-RERKKKKERKERERE----------------N 127
Query: 151 RQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEE 210
+Q ER +K R K R +E+ + ERG +R+R+ R+++ + + N + K+E
Sbjct: 128 KQRRERKRKKRR--KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE---RKKE 182
Query: 211 GERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSF 248
ER+ R+ R+ +R + R+K ++ R+ + S F
Sbjct: 183 RERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVF 220
Score = 77.0 bits (188), Expect = 9e-14
Identities = 55/231 (23%), Positives = 109/231 (47%), Gaps = 43/231 (18%)
Query: 88 RQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQE 147
R+ ER+++ ++REK K + RE E+ RGK +K++ +R R +E
Sbjct: 32 RESERKKERREREKRK---REREKERKRERGKKEKKKRKKRERGKE-------------- 74
Query: 148 TRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLY 207
R+R+ ER +++ K R + K E +R + R RR R++K
Sbjct: 75 -RERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKK---------------- 117
Query: 208 KEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHF 267
+ RK RE R+NK R + R+KR K + K + +R ++++ ++
Sbjct: 118 ------KERKERE--RENKQRRERK-RKKRRKKKRRKERKREKERGKRERKRKKRKKEER 168
Query: 268 DDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLV 318
+ +R ++ +RK++ + E R+R+ + + R + K+D + + ++ V
Sbjct: 169 EKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQV 219
Score = 70.9 bits (172), Expect = 6e-12
Identities = 50/210 (23%), Positives = 93/210 (44%), Gaps = 16/210 (7%)
Query: 146 QETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYW 205
+E R+R+ +R K R + + E+K ++RER+ +ER+ Q +
Sbjct: 38 KERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE--------- 88
Query: 206 LYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNS--FSDKGEERHKEKRHKE 263
+ E ERR RK + R+ K R + ++K+E+ +E+ N K ++R K+KR KE
Sbjct: 89 --RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
Query: 264 GFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGK 323
E+ + +RK K K E R+++ + + +++ + R K
Sbjct: 147 R---KREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
Query: 324 DKDSRRKHGHEEGSSVWWKLDQRPGGEETV 353
++ RK + S V+ L + TV
Sbjct: 204 ERKKDRKTDRQTDSQVFRPLRESAFNRVTV 233
Score = 58.2 bits (139), Expect = 4e-08
Identities = 55/191 (28%), Positives = 84/191 (43%), Gaps = 37/191 (19%)
Query: 169 SEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHR 228
SE K E ER RER +ERK + G K+E ++R ++ R +R+ K +
Sbjct: 34 SERKKERREREKRKRERE-KERKRERG------------KKEKKKRKKRERGKERERKRK 80
Query: 229 EKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPR 288
E REK+ K +EK ER K K+ K+ +R + R+E+ K E +
Sbjct: 81 E----REKQRKERREK---------ERRKRKKEKK------KRERKQRGRRERKKKKERK 121
Query: 289 KRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPG 348
+RE +N + R R KR + + GK + R+K EE K +R
Sbjct: 122 ERERENKQRRER-KRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE----KKRERNR 176
Query: 349 GEETVEIEKEE 359
E E E++E
Sbjct: 177 KERKKERERKE 187
Score = 57.0 bits (136), Expect = 9e-08
Identities = 32/128 (25%), Positives = 67/128 (52%), Gaps = 3/128 (2%)
Query: 5 KRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDA 64
K R K + + R+ + +++R RE+K +KE + E+K+ R R +
Sbjct: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRER---KRK 136
Query: 65 RSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKE 124
+ R + +E RG+R+R R++ ++ + + + + KE+ +E E+ R + +E++
Sbjct: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK 196
Query: 125 KDRRARKE 132
K+RR +KE
Sbjct: 197 KERRKKKE 204
Score = 57.0 bits (136), Expect = 9e-08
Identities = 28/105 (26%), Positives = 56/105 (53%), Gaps = 1/105 (0%)
Query: 29 GSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQ-DARSRDRVAEVHTAKESPRGERDRD 87
G +E +K +E+K R+ E K + R + R R++ K R + +R+
Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169
Query: 88 RQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKE 132
++RER R + +E+E+ + + R+ E+ R K +E++KDR+ ++
Sbjct: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQ 214
Score = 56.2 bits (134), Expect = 2e-07
Identities = 33/151 (21%), Positives = 81/151 (53%), Gaps = 2/151 (1%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E KR+ ++ + + RK + ++ER+ R+K+ +K+ E +E + +
Sbjct: 62 EKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKE-KKKRERKQRGRRERKKKKER 120
Query: 62 QDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDR 121
++ ++ K+ + +R ++R+RE+ R ++R+++K K++ RE ++ +R K+R
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNR-KER 179
Query: 122 EKEKDRRARKEELRQTVAHHNLLGQETRDRQ 152
+KE++R+ R+E ++ + +DR+
Sbjct: 180 KKERERKERRERKKERKKERRKKKERKKDRK 210
Score = 52.0 bits (123), Expect = 3e-06
Identities = 39/159 (24%), Positives = 71/159 (44%), Gaps = 17/159 (10%)
Query: 208 KEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHF 267
+ E ER+ + RE ++ + REK RE+ +K K++ K ER KE+ K
Sbjct: 31 QRESERKKER-REREKRKREREKERKRERGKKEKKKR------KKRERGKERERKR---- 79
Query: 268 DDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDS 327
ER + +R+EK + ++++ + + R R K+ + EN R K K
Sbjct: 80 -KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
Query: 328 RRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENAR 366
R+K +E K ++ G E ++++ + E R
Sbjct: 139 RKKKRRKER-----KREKERGKRERKRKKRKKEEREKKR 172
Score = 40.0 bits (92), Expect = 0.012
Identities = 30/110 (27%), Positives = 57/110 (51%), Gaps = 6/110 (5%)
Query: 4 GKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQD 63
G+R K + + R++ + K +K R K+ ++E E E K + R ++
Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK-RKKEER 168
Query: 64 ARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEK 113
+ R+R + KE R ER R+R++ER+ K+R K+K ++K R+ ++
Sbjct: 169 EKKRERNRK-ERKKERERKER-RERKKERK---KERRKKKERKKDRKTDR 213
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 87.0 bits (214), Expect = 8e-17
Identities = 90/448 (20%), Positives = 203/448 (45%), Gaps = 48/448 (10%)
Query: 14 KADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEV 73
+ + L++ +W +EE + +EKK+RK+ E + + R +Q+ + R++ ++
Sbjct: 266 QTNTLQEEMWR-----QEEELREQEKKIRKQEEKMWRQEERLR----EQEGKMREQEEKM 316
Query: 74 HTAKESPRGERDRDRQRERRRDAKDREKEKLKEKH-REAEKSHSRGKDREKEKDRRARKE 132
R R RE+ ++ +++EKE ++K RE E+ +++ E++ + R++
Sbjct: 317 W---------RQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQ 367
Query: 133 ELRQTVAHHNLLGQE----TRDRQLLERAERKGRSVSKVR-SEEKDEDSERGDEDRERRY 187
E + L QE +++++ ++ ER ++R EE+ + E+ E E+
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMR 427
Query: 188 RERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSST-REKREKYSKEKSN 246
E+K+Q + K +++ E+ + R +R+ K RE+ T RE+ EK K++ N
Sbjct: 428 EEKKMQEQEKKT--------RDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 479
Query: 247 SFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKR 306
+ + +E +++ ++ ++ + K +++ R +E G+ + K
Sbjct: 480 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 539
Query: 307 DGTSSQ--HAENLVRNHGK---DKDSRRKHGHEEGSSVWWKLDQRPGGEETV-EIEKEET 360
Q E +R+ + D++ R + +E W +++ EE + E EK+
Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599
Query: 361 DLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQ 420
+ E + E+ ++ E+ + + +E E E + + +E + +++E Q
Sbjct: 600 EEEEMMREQ-----EEKMQEQEEKMQ----EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 421 RAINAENERIGELSLKLFQKRGRTEFEK 448
E +R+ E KL++ E EK
Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQEK 678
Score = 86.7 bits (213), Expect = 1e-16
Identities = 90/458 (19%), Positives = 202/458 (44%), Gaps = 41/458 (8%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E R ++ W+ ++ LW ++E++ RE++ + + + ++ R R+ +
Sbjct: 361 EEKMREQEEKMWRQEE---RLW-------EQEKQMREQEQKMRDQEERMWEQDERLREKE 410
Query: 62 QDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDR 121
+ R ++++ E E R E+ Q ++ RD +++ +E +E+ RE EK K R
Sbjct: 411 ERMREQEKMWE---QVEKMREEKKMQEQEKKTRDQEEKMQE--EERIREREK-----KMR 460
Query: 122 EKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDE---DSER 178
E+E+ R ++E++++ N+ QE ++ Q E+K + + + +E++E + E
Sbjct: 461 EEEETMREQEEKMQK--QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518
Query: 179 GDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKRE 238
D+E + + K + K + ++++E + R ++ + D++ + +K+ +EK+
Sbjct: 519 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578
Query: 239 KYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRK-----EKSAKDEPRKRESQ 293
+EK ++ ER K+ R +E + E + K EK + E + +E +
Sbjct: 579 WDQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQE 637
Query: 294 N---GEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGE 350
+ ++ + E + +K ++ E+ +W +Q +
Sbjct: 638 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIW---EQEKMEK 694
Query: 351 ETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPL 410
+T E EK+ D E R + E + E+ + +E E E + + +E +
Sbjct: 695 KTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR----EQEEKMQEQEEKMQEQEEEM 750
Query: 411 AQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFEK 448
+++E Q E +R+ E KL++ E EK
Sbjct: 751 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788
Score = 64.7 bits (156), Expect = 4e-10
Identities = 67/363 (18%), Positives = 164/363 (45%), Gaps = 44/363 (12%)
Query: 13 WKADDLRKH---LWAIQSGGSKEERKHREKKLRKESEMDLPEHK----EPRCRDPDQDAR 65
W+ + +R+ +W + +E+K +++ R E + E K E + R+ + R
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE---R 590
Query: 66 SRDRVAEVHTAKESPRGERDRDRQRERRRDAKDR----EKEKLKEKHREAEKSHSRGKDR 121
R+R ++ +E R + ++ +++E + ++ ++EK++E+ + + + ++
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 122 EKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDE-DSERGD 180
E++ + R E ++ + H + ++ + ++ E+ + + K + +EK D E+
Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR 710
Query: 181 EDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTR-EKREK 239
E+ R RE+K++ +EE R ++ + +++ K +E+ E+ EK
Sbjct: 711 EEESMREREKKMR--------------EEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK 756
Query: 240 YSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRN 299
+++ + + KEK + + + Q + +E+ +D+ K Q E +
Sbjct: 757 MWEQEEKMWEQQRLPEQKEKL----WEHEKMQEQEKIWEQEEKMRDQEEKMRGQ--EEKM 810
Query: 300 RGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWW---KLDQRPGGEETVEIE 356
RG K G + + G+++ + G EE +W K++++ G+E E
Sbjct: 811 RGQEEKMRGQEEKMWGQEEKMWGQEE---KMWGQEE--KMWGQEEKMEEKMQGQEEKMRE 865
Query: 357 KEE 359
+EE
Sbjct: 866 QEE 868
Score = 55.1 bits (131), Expect = 4e-07
Identities = 51/274 (18%), Positives = 129/274 (47%), Gaps = 15/274 (5%)
Query: 1 MEPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDP 60
M+ + + + K + + +W + ++E K E++ E + L EH++ + ++
Sbjct: 619 MQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 678
Query: 61 DQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKD 120
Q+ + E K + ++ D+++ R ++ RE+EK K RE E+ ++
Sbjct: 679 MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM-REREK---KMREEEEMMREQEE 734
Query: 121 REKEKDRRARKEELRQTVAHHNLLGQETR--DRQLLERAERKGRSVSKVRSEEK--DEDS 176
+ +E++ + +++E + QE + ++Q L + K K++ +EK +++
Sbjct: 735 KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEE 794
Query: 177 ERGDEDRERRYRERKLQYGDSK--DNPLKYW-----LYKEEGERRHRKPREPDRDNKHRE 229
+ D++ + R +E K++ + K K W ++ +E + ++ + ++ K E
Sbjct: 795 KMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEE 854
Query: 230 KSSTREKREKYSKEKSNSFSDKGEERHKEKRHKE 263
K +E++ + +EK +K E+ ++ R +E
Sbjct: 855 KMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQE 888
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 85.5 bits (210), Expect = 2e-16
Identities = 104/461 (22%), Positives = 188/461 (40%), Gaps = 80/461 (17%)
Query: 20 KHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRC--RDPDQDARSRDRVAEVHTAK 77
K W +++ + K R K+ +++E+ ++ + R RD ++ RD E+ T +
Sbjct: 5 KDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI-TIR 63
Query: 78 ESP---------RGERDRD------RQRERRRDAKDREKEKLKEKHREA---EKSHSRGK 119
SP RGE D +Q R+ R+ EK KEK + A E+ H R K
Sbjct: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRK 123
Query: 120 DREKEKDRRAR---KEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDS 176
+E+D+ R +++ R+ H+ R+R LE+ ERK K+R ++K++
Sbjct: 124 RHREEQDKARREWERQKRREMAREHS-----RRERDRLEQLERKRERERKMREQQKEQ-- 176
Query: 177 ERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDN---KHREKSST 233
R ++RERR ER+ K + E HR RE D H +S
Sbjct: 177 -REQKERERRAEERR-----------KEREARREVSAHHRTMREDYSDKVKASHWSRSPP 224
Query: 234 REKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQ 293
R RE++ G + KE++ +E D + S+ +RK SA+ + S
Sbjct: 225 RPPRERFEL-------GDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 277
Query: 294 NGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETV 353
+ E + +G++S+ +E ++++ + E GS+ + +
Sbjct: 278 SEEEEEEEEEEEEEGSTSEESE-------EEEEEEEEEEEETGSN-----SEEASEQSAE 325
Query: 354 EIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEE------ 407
E+ +EE + R + + D E + +++ P+S E
Sbjct: 326 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDS 385
Query: 408 ---LPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTE 445
LP+ K+E+ + A+ G S++ FQ R E
Sbjct: 386 PALLPIELKQELPKYLPALQ------GCRSVEEFQCLNRIE 420
Score = 73.2 bits (178), Expect = 1e-12
Identities = 68/351 (19%), Positives = 138/351 (39%), Gaps = 23/351 (6%)
Query: 85 DRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLL 144
++D + + D +EK++ KE+ +AE + D K + ELR +
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
Query: 145 GQETRDRQLLERAERKGRSVS---KVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNP 201
R +E + S++ + K++ R DE R+ +++ +++
Sbjct: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVK-------- 115
Query: 202 LKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRH 261
+ E ERR R E D+ + E+ RE ++S+ + + +R +E++
Sbjct: 116 ------EREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKM 169
Query: 262 KEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNH 321
+E ++R Q +R+ + + E R + HR + + D + A + R+
Sbjct: 170 RE--QQKEQREQKERERRAEERRKEREARREVSAHHR----TMREDYSDKVKASHWSRSP 223
Query: 322 GKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDY 381
+ R + G K+++R + +I E +A + + + + E+
Sbjct: 224 PRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEE 283
Query: 382 EDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGE 432
E++ E +G E S E E E+ EE E Q A E + E
Sbjct: 284 EEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 334
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 85.1 bits (209), Expect = 3e-16
Identities = 76/281 (27%), Positives = 123/281 (43%), Gaps = 73/281 (25%)
Query: 30 SKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQ 89
SK E +H +E + + + R R+ D R RDR E T E ERDR R
Sbjct: 3 SKTEGRHTH------TETETMDRQRERRRETD---RERDRAKESKT--EDRHSERDRQRD 51
Query: 90 RERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETR 149
RER R+ +DR++E+ K+ RE E+ R +DR+++++ +++ R+T H ET
Sbjct: 52 RERNRE-RDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRH-----TET- 104
Query: 150 DRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKE 209
DR ER ++K R + +VR E+++ E G
Sbjct: 105 DR---ERQKQKEREMERVRDREREKQKEMG------------------------------ 131
Query: 210 EGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFH--- 266
R + RE DR+ RE+ + RE+ + G ER E RH+E
Sbjct: 132 ---RERQTDRETDRE---RERQAERER-------------ETGRERKTEDRHRERERERK 172
Query: 267 FDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRD 307
+ ER + +R+ + + R+RE+ R R + +RD
Sbjct: 173 RERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 63.5 bits (153), Expect = 1e-09
Identities = 61/244 (25%), Positives = 109/244 (44%), Gaps = 64/244 (26%)
Query: 87 DRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQ 146
DRQRERRR+ DRE+++ KE S+ +DR E+DR+ +E R+
Sbjct: 18 DRQRERRRET-DRERDRAKE---------SKTEDRHSERDRQRDRERNRE---------- 57
Query: 147 ETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWL 206
RDR+ ++ +R+G E+ + ER D DR+R
Sbjct: 58 RDRDREREKQTDREG---------ERQRERER-DRDRQR--------------------- 86
Query: 207 YKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFH 266
E ER K RE DR H E R+K+++ E+ D+ E+ KE +
Sbjct: 87 ---ETERERDKERETDR---HTETDRERQKQKEREMERVR---DREREKQKEMGRERQTD 137
Query: 267 FDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKD 326
+ +R + +R+ + ++ R+R++++ HR R KR+ + + R+ +++
Sbjct: 138 RETDRER---ERQAERERETGRERKTED-RHRERERERKRERERKRETKERERHTDMERE 193
Query: 327 SRRK 330
+R+
Sbjct: 194 RQRE 197
Score = 57.8 bits (138), Expect = 5e-08
Identities = 45/200 (22%), Positives = 79/200 (39%), Gaps = 14/200 (7%)
Query: 136 QTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYG 195
+T H ET DRQ R E S+ +D SER + R RER
Sbjct: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRE 63
Query: 196 DSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEER 255
K EGER+ + R+ DR + T +R+K + ++ +D+ ++
Sbjct: 64 REKQT-------DREGERQRERERDRDRQRE------TERERDKERETDRHTETDRERQK 110
Query: 256 HKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAE 315
KE R E + Q + R+ ++ ++ R+RE Q R G K + +
Sbjct: 111 QKE-REMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERER 169
Query: 316 NLVRNHGKDKDSRRKHGHEE 335
R + ++++ + H +
Sbjct: 170 ERKRERERKRETKERERHTD 189
Score = 55.1 bits (131), Expect = 4e-07
Identities = 35/128 (27%), Positives = 61/128 (47%), Gaps = 5/128 (3%)
Query: 5 KRRTKDDTWKADDLRKHLWAIQSGGSKEER-----KHREKKLRKESEMDLPEHKEPRCRD 59
+R T+ + K + +H + ++ER + RE++ +KE + +E
Sbjct: 85 QRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRER 144
Query: 60 PDQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGK 119
Q R R+ E T ER+R R+RER+R+ K+RE+ E+ R+ E R +
Sbjct: 145 ERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDR 204
Query: 120 DREKEKDR 127
RE E++R
Sbjct: 205 QRESERER 212
Score = 47.8 bits (112), Expect = 6e-05
Identities = 60/242 (24%), Positives = 97/242 (40%), Gaps = 34/242 (14%)
Query: 208 KEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHF 267
K EG H + DR RE+R + +E+ D+ +E E RH E
Sbjct: 4 KTEGRHTHTETETMDRQ---------RERRRETDRER-----DRAKESKTEDRHSER--- 46
Query: 268 DDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDS 327
D +R DR+ +D R+RE Q R +RD + E R K++++
Sbjct: 47 DRQR-----DRERNRERDRDREREKQTDREGERQRERERDRDRQRETE---RERDKERET 98
Query: 328 RRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEV 387
R H E K +R E V + E E R + T D + + + E
Sbjct: 99 DR---HTETDRERQKQKERE--MERVRDREREKQKEMGR-ERQTDRETDRERERQAERER 152
Query: 388 CDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFE 447
G + ++ + RE+ + +K+E +E +R + E ER E K ++R E E
Sbjct: 153 ETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQR---ESE 209
Query: 448 KE 449
+E
Sbjct: 210 RE 211
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 84.0 bits (206), Expect = 7e-16
Identities = 78/346 (22%), Positives = 145/346 (41%), Gaps = 38/346 (10%)
Query: 20 KHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRC--RDPDQDARSRDRVAEVHTAK 77
K W +++ + K R K+ +++E+ ++ + R RD ++ RD E+ T +
Sbjct: 5 KDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI-TIR 63
Query: 78 ESP---------RGERD------------RDRQRERRRDAKDREKEKLKEKHREAEKSHS 116
SP RGE D R + R+D K +EK+ + K +E E
Sbjct: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERR 123
Query: 117 RGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDS 176
+ E++K RR + + R+ +A + R+R LE+ ERK K+R ++K++
Sbjct: 124 KRHREEQDKARREWERQKRREMAREH----SRRERDRLEQLERKRERERKMREQQKEQRE 179
Query: 177 ERGDEDR-ERRYRERKLQYGDSKDNPLKYWLYKEEGERRH--RKPREPDR------DNKH 227
++ E R E R +ER+ + S + Y ++ + H R P P R D +
Sbjct: 180 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 239
Query: 228 REKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEP 287
K E+R+ S + S S++ + + G ++E + + +E S +E
Sbjct: 240 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 299
Query: 288 RKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGH 333
+ E + E S+ + S Q AE + + + R H
Sbjct: 300 EEEEEEEEEEEEETGSNSEE-ASEQSAEEVSEEEMSEDEERENENH 344
Score = 71.2 bits (173), Expect = 5e-12
Identities = 83/361 (22%), Positives = 147/361 (40%), Gaps = 42/361 (11%)
Query: 85 DRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLL 144
++D + + D +EK++ KE+ +AE + D DR ++++ L +
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSD-----DRDSKRDSLEE-------- 50
Query: 145 GQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDED-----RERRYRERKLQYGDSKD 199
E RD +E R S R E+ ED RG+ED + + RK + KD
Sbjct: 51 -GELRD-HCMEITIRN----SPYRREDSMED--RGEEDDSLAIKPPQQMSRKEKVHHRKD 102
Query: 200 NPLKYWLYKEEGERRHRKPREPDRDNKHREKSS------TREKREKYSKEKSNSFSDKGE 253
K +++ R K RE +R +HRE+ R+KR + ++E S D+ E
Sbjct: 103 EKRK----EKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLE 158
Query: 254 --ERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSS 311
ER +E+ K ++R Q +R+ + + E R + HR + + D +
Sbjct: 159 QLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR----TMREDYSDK 214
Query: 312 QHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYT 371
A + R+ + R + G K+++R + +I E +A + +
Sbjct: 215 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAE 274
Query: 372 ASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIG 431
+ + E+ E++ E +G E S E E E+ EE E Q A E +
Sbjct: 275 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS 334
Query: 432 E 432
E
Sbjct: 335 E 335
Score = 35.8 bits (81), Expect = 0.22
Identities = 42/205 (20%), Positives = 74/205 (36%), Gaps = 52/205 (25%)
Query: 32 EERKHREKKLR---------KESEMDLPEHKEPRCRDPDQDARSR-------DRVAEVHT 75
E ++ RE+K+R KE E E ++ R + A R D+V H
Sbjct: 161 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 220
Query: 76 AKESPRGERDRDRQRERRRDAKDR-----------------------------------E 100
++ PR R+R + R+ K+ E
Sbjct: 221 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 280
Query: 101 KEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERK 160
+E+ +E+ E E S S + E+E++ +E + +E + ++ E ER+
Sbjct: 281 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 340
Query: 161 GRSVSKVRSEEK-DEDSERGDEDRE 184
+ V E + D DS +E E
Sbjct: 341 NENHLLVVPESRFDRDSGESEEAEE 365
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 83.6 bits (205), Expect = 9e-16
Identities = 107/471 (22%), Positives = 189/471 (40%), Gaps = 90/471 (19%)
Query: 20 KHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRC--RDPDQDARSRDRVAEVHTAK 77
K W +++ + K R K+ +++E+ ++ + R RD ++ RD E+ T +
Sbjct: 5 KDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI-TIR 63
Query: 78 ESP---------RGERDRD------RQRERRRDAKDREKEKLKEKHREAEKS-----HSR 117
SP RGE D +Q R+ R+ EK KEK R S H+R
Sbjct: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHAR 123
Query: 118 GKDREKEKDRRARKEE-----------LRQTVAHHNLLGQETRDRQLLERAERKGRSVSK 166
K+RE E+ +R R+E+ R+ H+ R+R LE+ ERK K
Sbjct: 124 VKEREHERRKRHREEQDKARREWERQKRREMAREHS-----RRERDRLEQLERKRERERK 178
Query: 167 VRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDN- 225
+R ++K++ R ++RERR ER+ K + E HR RE D
Sbjct: 179 MREQQKEQ---REQKERERRAEERR-----------KEREARREVSAHHRTMREDYSDKV 224
Query: 226 --KHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSA 283
H +S R RE++ G + KE++ +E D + S+ +RK SA
Sbjct: 225 KASHWSRSPPRPPRERFEL-------GDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 277
Query: 284 KDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKL 343
+ + S + E + +G++S+ +E ++++ + E GS+
Sbjct: 278 ESSSAESGSGSEEEEEEEEEEEEEGSTSEESE-------EEEEEEEEEEEETGSN----- 325
Query: 344 DQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESRE 403
+ + E+ +EE + R + + D E + +++ P+S
Sbjct: 326 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 385
Query: 404 KLEE---------LPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTE 445
E LP+ K+E+ + A+ G S++ FQ R E
Sbjct: 386 LTEGDYVPDSPALLPIELKQELPKYLPALQ------GCRSVEEFQCLNRIE 430
Score = 75.9 bits (185), Expect = 2e-13
Identities = 77/317 (24%), Positives = 132/317 (41%), Gaps = 47/317 (14%)
Query: 9 KDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRD 68
+ D + + R H + + GG K RE + RK H+E + D+ R +
Sbjct: 100 RKDEKRKEKCRHHSHSAE-GGKHARVKEREHERRKR-------HRE----EQDKARREWE 147
Query: 69 RVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRR 128
R A+E R ERDR Q ER+R+ + + +E+ KE+ RE ++ R ++R KE++ R
Sbjct: 148 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQ-REQKERERRAEERRKEREAR 206
Query: 129 ARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYR 188
R+ AHH + ++ D+ R + R E D +E E R
Sbjct: 207 ------REVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 260
Query: 189 ERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSF 248
LQ D D+ RK + + S E+ E+ +E+ S
Sbjct: 261 LSDLQ--DISDS--------------ERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 304
Query: 249 SDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRG------- 301
S++ EE +E+ +E +E ++ + E+SA++ + S++ E N
Sbjct: 305 SEESEEEEEEEEEEE-----EETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 359
Query: 302 ASSKRDGTSSQHAENLV 318
+ RD S+ AE V
Sbjct: 360 SRFDRDSGESEEAEEEV 376
Score = 74.7 bits (182), Expect = 4e-13
Identities = 71/351 (20%), Positives = 137/351 (39%), Gaps = 13/351 (3%)
Query: 85 DRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLL 144
++D + + D +EK++ KE+ +AE + D K + ELR +
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
Query: 145 GQETRDRQLLERAERKGRSVS---KVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNP 201
R +E + S++ + K++ R DE R+ + R K
Sbjct: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHAR 123
Query: 202 LKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRH 261
+K + E ERR R E D+ + E+ RE ++S+ + + +R +E++
Sbjct: 124 VK----EREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKM 179
Query: 262 KEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNH 321
+E ++R Q +R+ + + E R + HR + + D + A + R+
Sbjct: 180 RE--QQKEQREQKERERRAEERRKEREARREVSAHHR----TMREDYSDKVKASHWSRSP 233
Query: 322 GKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDY 381
+ R + G K+++R + +I E +A + + + + E+
Sbjct: 234 PRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEE 293
Query: 382 EDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGE 432
E++ E +G E S E E E+ EE E Q A E + E
Sbjct: 294 EEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 344
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 83.6 bits (205), Expect = 9e-16
Identities = 92/443 (20%), Positives = 196/443 (44%), Gaps = 58/443 (13%)
Query: 14 KADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEV 73
+ + L++ +W +EE + +EKK+RK+ E + Q+ R R++ ++
Sbjct: 228 QTNTLQEEMWR-----QEEELREQEKKIRKQEE-----------KMWRQEERLREQEGKM 271
Query: 74 HTAKESPRGERDRDRQRERRRDAKDREKE-KLKEKHREAEKSHSRGKDREKEKDRRARKE 132
+E R R R RE+ ++ +++EKE + ++K RE E+ +++ E++ + R++
Sbjct: 272 REQEEKMR--RQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ 329
Query: 133 ELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKL 192
E + L QE + R+ E+K D E +++ R RE++
Sbjct: 330 EEKMWRQEERLWEQEKQMRE----------------QEQKMRDQEERMWEQDERLREKEE 373
Query: 193 QYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSST-REKREKYSKEKSNSFSDK 251
+ + + K W E+ E+ + R +R+ K RE+ T RE+ EK K++ N + +
Sbjct: 374 RMREQE----KMW---EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426
Query: 252 GEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSS 311
+E +++ ++ ++ + K +++ R +E G+ + K
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK----MR 482
Query: 312 QHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQ--RPGGEETVEIEKEETDLENARADA 369
+ + + K +D +K +E W+ D+ R E E +K E R +
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQE--ERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
Query: 370 YTASCEDDFEDYEDDFEVCDGDDDESSNEPESR-EKLEELPLAQKKEIQEIQRAINAENE 428
T E D E+ ++E E E + + EE+ Q++++QE + + + E
Sbjct: 541 KTQEQEKKTWDQEEKMR-----EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEE 595
Query: 429 RIGELSLKLFQKRGRTEFEKEPR 451
++ E K+ Q++ +E+E +
Sbjct: 596 KMWEQEEKM-QEQEEKMWEQEEK 617
Score = 76.3 bits (186), Expect = 1e-13
Identities = 81/440 (18%), Positives = 193/440 (43%), Gaps = 45/440 (10%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E R ++ W+ ++ LW + ++E+K R+++ R + + KE R R+ +
Sbjct: 323 EEKMREQEEKMWRQEE---RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 62 ----------QDARSRDRVAEVHTAKESPRGERDRDRQRERR---RDAKDREKEKLKEKH 108
++ R R+R ++ +E+ R + ++ +++E ++ K+ ++++L E
Sbjct: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE-- 437
Query: 109 REAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQET---RDRQLLERAERKGRSVS 165
+ EK + K +E+E+ ++E++R + GQE R ++ E+ ++
Sbjct: 438 -QKEKLWEQEKMQEQEEKIWEQEEKIRD---QEEMWGQEKKMWRQEKMREQEDQMWEQEE 493
Query: 166 KVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREP---- 221
K+R D++ + D++ ++ +L+ + + K +EE R +K +E
Sbjct: 494 KMR----DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 222 -DRDNKHREKSSTREKREKYSKEKS--NSFSDKGEERHKEKRHKEGFHFDDERHQSNVDR 278
D++ K RE+ RE+ +K +E+ +K +E+ ++ R +E ++ E +
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 279 KEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSS 338
K +++ ++E ++ +++ + E + K ++ K +E
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE--- 666
Query: 339 VWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNE 398
++ G EE + ++E+ + + E E G +++ +
Sbjct: 667 -----EKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQ 721
Query: 399 PESREKLEELPLAQKKEIQE 418
E REK EE QK+++QE
Sbjct: 722 EEMREK-EERIRDQKEKMQE 740
Score = 67.0 bits (162), Expect = 9e-11
Identities = 66/325 (20%), Positives = 142/325 (43%), Gaps = 18/325 (5%)
Query: 19 RKHLWAIQSGGSKEERK-HREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAK 77
++ LW + +EE+ +E+K+R + EM E K R + R++ ++ +
Sbjct: 439 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR------QEKMREQEDQMWEQE 492
Query: 78 ESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQT 137
E R + + +E R +D E+L+EK + + EK ++ + +E+ ++T
Sbjct: 493 EKMRDQEQKMWDQEERMWEQD---ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 138 VAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRY-RERKLQYGD 196
+ +E R R+ E+ R+ + + + E+ E E+ E E+ + +E K+Q +
Sbjct: 550 WDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608
Query: 197 SK--DNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEE 254
K + K W +EE + + ++ +++ K +E+ ++E+ +E+ E+
Sbjct: 609 EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR---EQ 665
Query: 255 RHKEKRHKEGFHFDDERHQSNVDR-KEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQH 313
K + +E +E+ Q ++ +E+ K ++ + E + G K G
Sbjct: 666 EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMR 725
Query: 314 AENLVRNHGKDKDSRRKHGHEEGSS 338
+ K+K R HEE S
Sbjct: 726 EKEERIRDQKEKMQERLPEHEERCS 750
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 81.3 bits (199), Expect = 5e-15
Identities = 100/457 (21%), Positives = 188/457 (41%), Gaps = 58/457 (12%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E K + + WK D G ++E+K RE+ +KE ++ E E + +
Sbjct: 691 EGEKELAEKEEWKKRD-----------GEEQEQKEREQGHQKERNQEMEEGGEEEHGEGE 739
Query: 62 QDARSRDRVAEVH-TAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKD 120
++ R+ E KE GE + + ER ++ +R+KE+ K + E+ +G+
Sbjct: 740 EEEGDREEEEEKEGEGKEEGEGE---EVEGEREKEEGERKKEERAGKEEKGEEEGDQGEG 796
Query: 121 REKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGD 180
E+E + R ++E E E +G V + + E ++E+ E G+
Sbjct: 797 EEEETEGRGEEKE---------------------EGGEVEGGEVEEGKGE-REEEEEEGE 834
Query: 181 EDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKY 240
+ E E + G+ ++ K +EEGE + + + + E+ E E+
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGK---GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEG 891
Query: 241 SKEKSNSFSDKGEERHKEKRHKEGFHFDDE-RHQSNVDRKEKSAKDEPRKRESQNGEHRN 299
E ++GE +E+ EG + E + + + E ++E + E ++GE
Sbjct: 892 EGEGE---EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEG 948
Query: 300 RGASSKRDGTSSQ-HAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKE 358
+ +G + E G+ ++ + EEG + ++ G EE E +
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG---EGEEEEGEEEGEEEGEG 1005
Query: 359 ETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKL---EELPLAQKKE 415
E + E + E + E E + E G+++E E E REK EE +++E
Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEEGEGE---GEEEEGEEEGEEREKEGEGEENRRNREEE 1062
Query: 416 IQE---IQRAINAENER-IGELSLKLFQKRGRTEFEK 448
+E Q ENER GE K+ + +G ++ K
Sbjct: 1063 EEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGK 1099
Score = 78.6 bits (192), Expect = 3e-14
Identities = 96/437 (21%), Positives = 171/437 (39%), Gaps = 31/437 (7%)
Query: 28 GGSKEERKHREKKLRKESEMDLPEHKE-------PRCRDPDQDARSRDRVAEVHTAKESP 80
GG KE+ + L ++E+ + K P R D AE +E
Sbjct: 617 GGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRG-DGTCEEGSSGAEHWQDEERE 675
Query: 81 RGERDRDR-QRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVA 139
+GE+D+ R + ER + + EK + K R+ E+ + +++ +K+R EE +
Sbjct: 676 KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE--E 733
Query: 140 HHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERR--YRERKLQYGDS 197
H +E DR+ E E +G+ + E + + E G+ +E R E+ + GD
Sbjct: 734 EHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQ 793
Query: 198 KDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHK 257
+ +EE E R + E + E+ E+ + + +GEE
Sbjct: 794 GEGE------EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEG 847
Query: 258 EKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENL 317
E +EG +E + +E + + E GE G + E
Sbjct: 848 EGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907
Query: 318 VRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDD 377
G++++ K G EEG + G EE E E E+ + E + E++
Sbjct: 908 GEGEGEEEEGEGK-GEEEGEE-----GEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961
Query: 378 -----FEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGE 432
E+ E + E +G+ +E E E E+ E ++ E +E + E E GE
Sbjct: 962 GEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE-EGEGEGEEEEEGE 1020
Query: 433 LSLKLFQKRGRTEFEKE 449
+ ++ + G E E+E
Sbjct: 1021 VEGEVEGEEGEGEGEEE 1037
Score = 60.5 bits (145), Expect = 8e-09
Identities = 81/379 (21%), Positives = 148/379 (39%), Gaps = 75/379 (19%)
Query: 91 ERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRD 150
E + A+D + ++E+ EA + + + KEK +L + D
Sbjct: 588 EEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTE---------------ILSDDLTD 632
Query: 151 RQLLERAERKGRSVSKVRS----------EE--------KDEDSERGDEDRERRYRERKL 192
+ E +E K +SV + EE +DE+ E+G++D+ R ER
Sbjct: 633 KA--EVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERP- 689
Query: 193 QYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKG 252
G+ + KE E+ K R+ E+ +E+ + + KE++ + G
Sbjct: 690 --GEGE---------KELAEKEEWKKRDG-------EEQEQKEREQGHQKERNQEMEEGG 731
Query: 253 EERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQ 312
EE H E +EG ++E + ++E ++ +RE + GE + + K +
Sbjct: 732 EEEHGEGEEEEGDR-EEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKG--- 787
Query: 313 HAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIE--KEETDLENARADAY 370
+++ + G EE + + + G E E+E K E + E +
Sbjct: 788 -----------EEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGE 836
Query: 371 TASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERI 430
E + E+ E + E +G +E E E E+ EE + E +E + E E
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE----GEGEGEEEEGEGEGEEEGE 892
Query: 431 GELSLKLFQKRGRTEFEKE 449
GE + + G E E E
Sbjct: 893 GEGEEEEGEGEGEEEGEGE 911
Score = 46.2 bits (108), Expect = 2e-04
Identities = 39/211 (18%), Positives = 87/211 (41%), Gaps = 1/211 (0%)
Query: 29 GSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDR 88
G +EE + + ++ +E E + E +E D + + E +E GE + +
Sbjct: 912 GEEEEGEGKGEEEGEEGEGE-GEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEG 970
Query: 89 QRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQET 148
+ E + E+E+ + + E E ++ E E++ EE + + G+E
Sbjct: 971 EGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEG 1030
Query: 149 RDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYK 208
E E +G K E++ + +E+ E +Y+E + + +D + K
Sbjct: 1031 EGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSK 1090
Query: 209 EEGERRHRKPREPDRDNKHREKSSTREKREK 239
+G ++ K + + + + + +E+R K
Sbjct: 1091 IKGSVKYGKHKTYQKKSVTNTQGNGKEQRSK 1121
Score = 44.3 bits (103), Expect = 6e-04
Identities = 56/310 (18%), Positives = 112/310 (36%), Gaps = 20/310 (6%)
Query: 31 KEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQR 90
K ER+ E++ E E E +E + + + + + E +E GE + + +
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882
Query: 91 ---------ERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHH 141
E + ++ E E +E E E+ GK E+ ++ EE
Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE 942
Query: 142 NLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSE-RGDEDR------ERRYRERKLQY 194
+ G+ + E E +G + E + E+ E G+E+ E E +
Sbjct: 943 DGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002
Query: 195 GDSKDNPLKYWLYKEEGERRHRKPREPDR----DNKHREKSSTREKREKYSKEKSNSFSD 250
G+ ++ +EEGE E + + E+ REK + + + N +
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEE 1062
Query: 251 KGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTS 310
+ EE ++ +E D V + + S K K + +G ++
Sbjct: 1063 EEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKM 1122
Query: 311 SQHAENLVRN 320
++ L++N
Sbjct: 1123 PVQSKRLLKN 1132
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 81.3 bits (199), Expect = 5e-15
Identities = 78/351 (22%), Positives = 145/351 (41%), Gaps = 39/351 (11%)
Query: 20 KHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRC--RDPDQDARSRDRVAEVHTAK 77
K W +++ + K R K+ +++E+ ++ + R RD ++ RD E+ T +
Sbjct: 5 KDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI-TIR 63
Query: 78 ESP---------RGERD------------RDRQRERRRDAKDREKEKLKEKHREAEKSHS 116
SP RGE D R + R+D K +EK+ + K +E E
Sbjct: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERR 123
Query: 117 RGKDREKEKDRRARKEELRQTVAHHNLLGQETRD-----RQLLERAERKGRSVSKVRSEE 171
+ E++K RR + + R+ +A + + D R LE+ ERK K+R ++
Sbjct: 124 KRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQ 183
Query: 172 KDEDSERGDEDR-ERRYRERKLQYGDSKDNPLKYWLYKEEGERRH--RKPREPDR----- 223
K++ ++ E R E R +ER+ + S + Y ++ + H R P P R
Sbjct: 184 KEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFEL 243
Query: 224 -DNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKS 282
D + K E+R+ S + S S++ + + G ++E + + +E S
Sbjct: 244 GDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGS 303
Query: 283 AKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGH 333
+E + E + E S+ + S Q AE + + + R H
Sbjct: 304 TSEESEEEEEEEEEEEEETGSNSEE-ASEQSAEEVSEEEMSEDEERENENH 353
Score = 70.5 bits (171), Expect = 8e-12
Identities = 86/366 (23%), Positives = 147/366 (40%), Gaps = 43/366 (11%)
Query: 85 DRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLL 144
++D + + D +EK++ KE+ +AE + D DR ++++ L +
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSD-----DRDSKRDSLEE-------- 50
Query: 145 GQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDED--------RERRYRERKLQYGD 196
E RD +E R S R E+ ED RG+ED ++ +E+ D
Sbjct: 51 -GELRD-HCMEITIRN----SPYRREDSMED--RGEEDDSLAIKPPQQMSRKEKVHHRKD 102
Query: 197 SKDNPLKYWLYKE---EGERRHRKPREPDRDNKHREKSSTRE-KREKYSKEKSNS----F 248
K K+ KE E ERR R E D+ + E+ RE RE +E+ N F
Sbjct: 103 EKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLF 162
Query: 249 SDKGE--ERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKR 306
D+ E ER +E+ K ++R Q +R+ + + E R + HR + +
Sbjct: 163 RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHR----TMRE 218
Query: 307 DGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENAR 366
D + A + R+ + R + G K+++R + +I E +A
Sbjct: 219 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAE 278
Query: 367 ADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAE 426
+ + + + E+ E++ E +G E S E E E+ EE E Q A
Sbjct: 279 SSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 338
Query: 427 NERIGE 432
E + E
Sbjct: 339 EEEMSE 344
Score = 35.8 bits (81), Expect = 0.22
Identities = 42/205 (20%), Positives = 74/205 (36%), Gaps = 52/205 (25%)
Query: 32 EERKHREKKLR---------KESEMDLPEHKEPRCRDPDQDARSR-------DRVAEVHT 75
E ++ RE+K+R KE E E ++ R + A R D+V H
Sbjct: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 229
Query: 76 AKESPRGERDRDRQRERRRDAKDR-----------------------------------E 100
++ PR R+R + R+ K+ E
Sbjct: 230 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 289
Query: 101 KEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERK 160
+E+ +E+ E E S S + E+E++ +E + +E + ++ E ER+
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Query: 161 GRSVSKVRSEEK-DEDSERGDEDRE 184
+ V E + D DS +E E
Sbjct: 350 NENHLLVVPESRFDRDSGESEEAEE 374
Score = 31.6 bits (70), Expect = 4.2
Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 10/103 (9%)
Query: 24 AIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGE 83
A GS+EE + E++ + S + E +E + +++ S A +A+E E
Sbjct: 282 AESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEE 341
Query: 84 RDRDRQRER----------RRDAKDREKEKLKEKHREAEKSHS 116
D +RE R D E E+ +E+ E S
Sbjct: 342 MSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 384
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 81.3 bits (199), Expect = 5e-15
Identities = 79/341 (23%), Positives = 144/341 (42%), Gaps = 39/341 (11%)
Query: 6 RRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEM-DLPEHKEPRCRDPDQDA 64
R +K D+ + +LR H + E R R+E M D E + P Q
Sbjct: 7 RDSKRDSLEEGELRDH---------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQM 57
Query: 65 RSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKE 124
+++V H K+ E+ ++++R R A+ + ++KEK RE H R K +E
Sbjct: 58 SRKEKV---HHRKD----EKRKEKRRHRSHSAEGGKHARVKEKERE----HERRKRHREE 106
Query: 125 KDRRAR---KEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDE 181
+D+ R +++ R+ H+ R+R LE+ ERK K+R ++K++ ++ E
Sbjct: 107 QDKARREWERQKRREMAREHS-----RRERDRLEQLERKRERERKMREQQKEQREQKERE 161
Query: 182 DR-ERRYRERKLQYGDSKDNPLKYWLYKEEGERRH--RKPREPDR------DNKHREKSS 232
R E R +ER+ + S + Y ++ + H R P P R D + K
Sbjct: 162 RRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEE 221
Query: 233 TREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRES 292
E+R+ S + S S++ + + G ++E + + +E S +E + E
Sbjct: 222 KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE 281
Query: 293 QNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGH 333
+ E S+ + S Q AE + + + R H
Sbjct: 282 EEEEEEEETGSNSEE-ASEQSAEEVSEEEMSEDEERENENH 321
Score = 68.2 bits (165), Expect = 4e-11
Identities = 79/390 (20%), Positives = 156/390 (40%), Gaps = 75/390 (19%)
Query: 26 QSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERD 85
QS +R E+ ++ M++ P R+ + DR E + P +
Sbjct: 3 QSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSME----DRGEEDDSLAIKPPQQMS 58
Query: 86 RDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLG 145
R + R+D K +EK + + E K H+R K++E+E +RR R E
Sbjct: 59 RKEKVHHRKDEKRKEKRRHRSHSAEGGK-HARVKEKEREHERRKRHRE------------ 105
Query: 146 QETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYW 205
++ + R+ ER +R+ ++ E + +R ++ +R RERK++
Sbjct: 106 EQDKARREWERQKRR-----EMAREHSRRERDRLEQLERKRERERKMR------------ 148
Query: 206 LYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGF 265
+++ E+R +K RE + + +E+ + RE + + +SDK + H +
Sbjct: 149 --EQQKEQREQKERERRAEERRKEREARREV-SAHHRTMREDYSDKVKASHWSR------ 199
Query: 266 HFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDK 325
+ P + + G+ R K + +L+ +
Sbjct: 200 -----------------SPPRPPRERFELGDGRKPVKEEKME------ERDLLSDLQDIS 236
Query: 326 DSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDYEDDF 385
DS RK E SS + G E E E+EE + E + ++ E++ E+ E++
Sbjct: 237 DSERKTSSAESSSA-----ESGSGSEEEEEEEEEEEEEGSTSE----ESEEEEEEEEEEE 287
Query: 386 EVCDGDDDESSNEPESREKLEELPLAQKKE 415
E + +E+S + EE+ +++E
Sbjct: 288 EETGSNSEEASEQSAEEVSEEEMSEDEERE 317
Score = 54.3 bits (129), Expect = 6e-07
Identities = 56/298 (18%), Positives = 115/298 (38%), Gaps = 12/298 (4%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E GK + + + RK Q +E + + +++ +E + E R +
Sbjct: 83 EGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRE 142
Query: 62 QDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSH-SRGKD 120
++ + R++ E KE R +R ++RE RR+ + ++ + + SH SR
Sbjct: 143 RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 202
Query: 121 R---------EKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEE 171
R + K + K E R ++ + R E + + S S+ EE
Sbjct: 203 RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE 262
Query: 172 KDEDSERG--DEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHRE 229
++E+ E G E+ E E + + ++ N + E + +R+N++
Sbjct: 263 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 322
Query: 230 KSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEP 287
+ ++ S E + + GE + EG + D S ++ K++ K P
Sbjct: 323 LVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP 380
Score = 51.2 bits (121), Expect = 5e-06
Identities = 61/292 (20%), Positives = 109/292 (37%), Gaps = 34/292 (11%)
Query: 165 SKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRD 224
S R E+ ED RG+ED + + K ++ + E+R K R
Sbjct: 31 SPYRREDSMED--RGEEDDSLAIKPPQQMSRKEK-------VHHRKDEKRKEKRRHRSHS 81
Query: 225 NKHREKSSTREKREKYSKEKSN-SFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSA 283
+ + + +EK ++ + K + DK + ++ +E R + +++ E+
Sbjct: 82 AEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKR 141
Query: 284 KDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKL 343
+ E + RE Q E R + +R + E + R + + +S W +
Sbjct: 142 ERERKMREQQK-EQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 200
Query: 344 DQRP--------GGEETVEIEKEE-----------TDLENARADAYTASCE----DDFED 380
RP G + V+ EK E +D E + A ++S E + E+
Sbjct: 201 PPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEE 260
Query: 381 YEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGE 432
E++ E +G E S E E E+ EE E Q A E + E
Sbjct: 261 EEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 312
Score = 32.0 bits (71), Expect = 3.2
Identities = 34/164 (20%), Positives = 66/164 (40%), Gaps = 2/164 (1%)
Query: 292 SQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEE 351
SQ+ + ++ S + E +RN ++ + EE S+ K Q+ +E
Sbjct: 2 SQSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKE 61
Query: 352 TVEIEKEETDLENARADAYTA--SCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELP 409
V K+E E R +++A ++ E + E +E E+ +
Sbjct: 62 KVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRRE 121
Query: 410 LAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFEKEPRTD 453
+A++ +E R E +R E ++ QK R + E+E R +
Sbjct: 122 MAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAE 165
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 81.3 bits (199), Expect = 5e-15
Identities = 79/341 (23%), Positives = 144/341 (42%), Gaps = 39/341 (11%)
Query: 6 RRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEM-DLPEHKEPRCRDPDQDA 64
R +K D+ + +LR H + E R R+E M D E + P Q
Sbjct: 41 RDSKRDSLEEGELRDH---------RMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQM 91
Query: 65 RSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKE 124
+++V H K+ E+ ++++R R A+ + ++KEK RE H R K +E
Sbjct: 92 SRKEKV---HHRKD----EKRKEKRRHRSHSAEGGKHARVKEKERE----HERRKRHREE 140
Query: 125 KDRRAR---KEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDE 181
+D+ R +++ R+ H+ R+R LE+ ERK K+R ++K++ ++ E
Sbjct: 141 QDKARREWERQKRREMAREHS-----RRERDRLEQLERKRERERKMREQQKEQREQKERE 195
Query: 182 DR-ERRYRERKLQYGDSKDNPLKYWLYKEEGERRH--RKPREPDR------DNKHREKSS 232
R E R +ER+ + S + Y ++ + H R P P R D + K
Sbjct: 196 RRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEE 255
Query: 233 TREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRES 292
E+R+ S + S S++ + + G ++E + + +E S +E + E
Sbjct: 256 KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEE 315
Query: 293 QNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGH 333
+ E S+ + S Q AE + + + R H
Sbjct: 316 EEEEEEEETGSNSEE-ASEQSAEEVSEEEMSEDEERENENH 355
Score = 73.9 bits (180), Expect = 7e-13
Identities = 89/418 (21%), Positives = 170/418 (40%), Gaps = 93/418 (22%)
Query: 20 KHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRC--RDPDQDARSRDRVAEVHTAK 77
K W +++ + K R K+ +++E+ ++ + R RD ++ RD E+ T +
Sbjct: 5 KDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI-TIR 63
Query: 78 ESP---------RGERDRD------RQRERRRDAKDREKEKLKEKHREAEKS-----HSR 117
SP RGE D +Q R+ R+ EK KEK R S H+R
Sbjct: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHAR 123
Query: 118 GKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSE 177
K++E+E +RR R E ++ + R+ ER +R+ ++ E + +
Sbjct: 124 VKEKEREHERRKRHRE------------EQDKARREWERQKRR-----EMAREHSRRERD 166
Query: 178 RGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKR 237
R ++ +R RERK++ +++ E+R +K RE + + +E+ + RE
Sbjct: 167 RLEQLERKRERERKMR--------------EQQKEQREQKERERRAEERRKEREARREV- 211
Query: 238 EKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEH 297
+ + +SDK + H + + P + + G+
Sbjct: 212 SAHHRTMREDYSDKVKASHWSR-----------------------SPPRPPRERFELGDG 248
Query: 298 RNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEK 357
R K + +L+ + DS RK E SS + G E E E+
Sbjct: 249 RKPVKEEKME------ERDLLSDLQDISDSERKTSSAESSSA-----ESGSGSEEEEEEE 297
Query: 358 EETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKE 415
EE + E + ++ E++ E+ E++ E + +E+S + EE+ +++E
Sbjct: 298 EEEEEEGSTSE----ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351
Score = 58.5 bits (140), Expect = 3e-08
Identities = 78/372 (20%), Positives = 143/372 (38%), Gaps = 53/372 (14%)
Query: 85 DRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLL 144
++D + + D +EK++ KE+ +AE + D DR ++++ L +
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSD-----DRDSKRDSLEEG------- 51
Query: 145 GQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKY 204
E RD ++ E R S R E+ ED RG+ED + + K
Sbjct: 52 --ELRDHRM-EITIRN----SPYRREDSMED--RGEEDDSLAIKPPQQMSRKEK------ 96
Query: 205 WLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSN-SFSDKGEERHKEKRHKE 263
++ + E+R K R + + + +EK ++ + K + DK + ++ +E
Sbjct: 97 -VHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRRE 155
Query: 264 GFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGK 323
R + +++ E+ + E + RE Q E R + +R + E
Sbjct: 156 MAREHSRRERDRLEQLERKRERERKMREQQK-EQREQKERERRAEERRKEREARREVSAH 214
Query: 324 DKDSRRKHGHEEGSSVWWKLDQRP--------GGEETVEIEKEE-----------TDLEN 364
+ R + + +S W + RP G + V+ EK E +D E
Sbjct: 215 HRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSER 274
Query: 365 ARADAYTASCE----DDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQ 420
+ A ++S E + E+ E++ E +G E S E E E+ EE E Q
Sbjct: 275 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ 334
Query: 421 RAINAENERIGE 432
A E + E
Sbjct: 335 SAEEVSEEEMSE 346
Score = 54.3 bits (129), Expect = 6e-07
Identities = 56/298 (18%), Positives = 115/298 (38%), Gaps = 12/298 (4%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E GK + + + RK Q +E + + +++ +E + E R +
Sbjct: 117 EGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRE 176
Query: 62 QDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSH-SRGKD 120
++ + R++ E KE R +R ++RE RR+ + ++ + + SH SR
Sbjct: 177 RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 236
Query: 121 R---------EKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEE 171
R + K + K E R ++ + R E + + S S+ EE
Sbjct: 237 RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE 296
Query: 172 KDEDSERG--DEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHRE 229
++E+ E G E+ E E + + ++ N + E + +R+N++
Sbjct: 297 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHL 356
Query: 230 KSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEP 287
+ ++ S E + + GE + EG + D S ++ K++ K P
Sbjct: 357 LVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLP 414
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 80.9 bits (198), Expect = 6e-15
Identities = 88/450 (19%), Positives = 197/450 (43%), Gaps = 41/450 (9%)
Query: 2 EPGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
E RR ++ W+ ++ + +E +E+K+R++ EM + E +E R +
Sbjct: 334 EEKMRRQEEMMWEKEEKMRR--------QEEMMWEKEEKMRRQEEM-MWEKEEKMRRQEE 384
Query: 62 QDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDR 121
+++ E+ E E+++ R++E +R +++ +E+ K + +EA+ K R
Sbjct: 385 MMWEKEEKIREL----EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 440
Query: 122 EKE-KDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGD 180
E+E K R K+ RQ H +++ + E++ R EEK + E
Sbjct: 441 EQEEKIREQEKKMWRQEEKIH--------EQEKIREEEKRQEQEEMWRQEEKIHEQEEIW 492
Query: 181 EDRERRY-RERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREK 239
+E+ + +E K++ + K W +E+ + K RE + + R++ RE+ E
Sbjct: 493 RQKEKMHEQEEKIRKQEEK-----VWRQEEKIREQEEKIREQE-EKMWRQEEKIREQEEM 546
Query: 240 YSKEKSNSFSDKGEERHKEKRHKEGFHFDDER---HQSNVDRKEKSAKDEPRKRESQNGE 296
+ +E+ +K E K + ++ +E+ + V R+E+ +++ KR+ Q +
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 297 HRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIE 356
+ + Q E +R ++K ++ +E + +++ +E E
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQ-EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 665
Query: 357 KEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESRE-KLEELPLAQKKE 415
+EET R + E + E+ + +E E E + + EE Q+++
Sbjct: 666 QEET---MWRQEEKIREQEKKIREQEEKIR----EQEEMMQEQEEKMWEQEEKMCEQEEK 718
Query: 416 IQEIQRAINAENERIGELSLKLFQKRGRTE 445
+QE + + + E++ E ++L Q+ + +
Sbjct: 719 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 76.3 bits (186), Expect = 1e-13
Identities = 73/370 (19%), Positives = 163/370 (44%), Gaps = 24/370 (6%)
Query: 89 QRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQE- 147
++ + ++ K RE+E EK RE E+ R ++ EK+ + R++E + QE
Sbjct: 314 EKIQEQEEKIREQE---EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 370
Query: 148 ---TRDRQLLERAERKGRSVSKVRS-EEKDEDSERGDEDRERRYRERKLQYGDSK-DNPL 202
++ ++ + E K+R EEK + E+ E E+R E K++ + + +
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 430
Query: 203 KYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHK 262
K W R+ K RE + + +EK R++ + + +EK +K +E+ + R +
Sbjct: 431 KMW-------RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE-EEKRQEQEEMWRQE 482
Query: 263 EGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHG 322
E H +E + +KEK + E + R+ + R +++ + E + R
Sbjct: 483 EKIHEQEEIWR----QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEE 538
Query: 323 KDKDSRRKHGHEE---GSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFE 379
K ++ EE W+ ++R E+ + ++E+ + + + E
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 380 DYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGELSLKLFQ 439
++ E +++ + E ++ EE Q+++I+E + + E++GE K+ +
Sbjct: 599 KRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 658
Query: 440 KRGRTEFEKE 449
+ + + ++E
Sbjct: 659 QEEKMQEQEE 668
Score = 62.8 bits (151), Expect = 2e-09
Identities = 60/357 (16%), Positives = 154/357 (43%), Gaps = 6/357 (1%)
Query: 98 DREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERA 157
+R ++ +EK E+ +++ +E++ + R++E + + QE + E+
Sbjct: 292 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 351
Query: 158 ERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRK 217
R+ + + + + ++ +++ + R +E + + K L+ ++++E R +
Sbjct: 352 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 411
Query: 218 PREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEK-RHKEGFHFDDERHQSNV 276
R+ + + +EK +E + +EK +K E+ K+ R +E H ++ +
Sbjct: 412 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 471
Query: 277 DRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEG 336
++++ + K Q R + +++ + E + R K ++ K E+
Sbjct: 472 RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI-REQE 530
Query: 337 SSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDF----EDYEDDFEVCDGDD 392
+W + ++ EE E++ + E + ED E + E +
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE 590
Query: 393 DESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFEKE 449
++ + E R++ EE Q+++I+E + I + E+I E K+ ++ T+ ++E
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 80.9 bits (198), Expect = 6e-15
Identities = 70/317 (22%), Positives = 131/317 (41%), Gaps = 18/317 (5%)
Query: 26 QSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERD 85
QS +R E+ ++ M++ P R+ + DR E + P +
Sbjct: 3 QSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSME----DRGEEDDSLAIKPPQQMS 58
Query: 86 RDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLG 145
R + R+D K +EK+ + K +E E + E++K RR + + R+ +A +
Sbjct: 59 RKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREH--- 115
Query: 146 QETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDR-ERRYRERKLQYGDSKDNPLKY 204
R+R LE+ ERK K+R ++K++ ++ E R E R +ER+ + S +
Sbjct: 116 -SRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMR 174
Query: 205 WLYKEEGERRH--RKPREPDR------DNKHREKSSTREKREKYSKEKSNSFSDKGEERH 256
Y ++ + H R P P R D + K E+R+ S + S S++
Sbjct: 175 EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 234
Query: 257 KEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAEN 316
+ + G ++E + + +E S +E + E + E S+ + S Q AE
Sbjct: 235 ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE-ASEQSAEE 293
Query: 317 LVRNHGKDKDSRRKHGH 333
+ + + R H
Sbjct: 294 VSEEEMSEDEERENENH 310
Score = 63.9 bits (154), Expect = 8e-10
Identities = 70/334 (20%), Positives = 141/334 (42%), Gaps = 36/334 (10%)
Query: 85 DRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARK---EELRQTVAHH 141
DRD +R+ + + R+ + +DR +E D A K + R+ HH
Sbjct: 6 DRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHH 65
Query: 142 NLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNP 201
E R + R + K R + + +++D R + +R++R RE ++ + +
Sbjct: 66 RK--DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKR-REMAREHSRRERDR 122
Query: 202 LKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRH 261
L+ K E ER+ R+ ++ R+ K RE+ + ++E+ ++ + ++ H+ R
Sbjct: 123 LEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSA-------HHRTMR- 174
Query: 262 KEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNH 321
+D + +S PR+R + G+ R K + +L+ +
Sbjct: 175 ------EDYSDKVKASHWSRSPPRPPRER-FELGDGRKPVKEEKME------ERDLLSDL 221
Query: 322 GKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASCEDDFEDY 381
DS RK E SS + G E E E+EE + E + ++ E++ E+
Sbjct: 222 QDISDSERKTSSAESSSA-----ESGSGSEEEEEEEEEEEEEGSTSE----ESEEEEEEE 272
Query: 382 EDDFEVCDGDDDESSNEPESREKLEELPLAQKKE 415
E++ E + +E+S + EE+ +++E
Sbjct: 273 EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 306
Score = 50.1 bits (118), Expect = 1e-05
Identities = 50/248 (20%), Positives = 94/248 (37%), Gaps = 25/248 (10%)
Query: 209 EEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSN-SFSDKGEERHKEKRHKEGFHF 267
++ R+ + D K ++ + +EK ++ + K + DK + ++ +E
Sbjct: 55 QQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMARE 114
Query: 268 DDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDS 327
R + +++ E+ + E + RE Q E R + +R + E +
Sbjct: 115 HSRRERDRLEQLERKRERERKMREQQK-EQREQKERERRAEERRKEREARREVSAHHRTM 173
Query: 328 RRKHGHEEGSSVWWKLDQRP--------GGEETVEIEKEE-----------TDLENARAD 368
R + + +S W + RP G + V+ EK E +D E +
Sbjct: 174 REDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSS 233
Query: 369 AYTASCE----DDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAIN 424
A ++S E + E+ E++ E +G E S E E E+ EE E Q A
Sbjct: 234 AESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 293
Query: 425 AENERIGE 432
E + E
Sbjct: 294 VSEEEMSE 301
Score = 35.8 bits (81), Expect = 0.22
Identities = 42/205 (20%), Positives = 74/205 (36%), Gaps = 52/205 (25%)
Query: 32 EERKHREKKLR---------KESEMDLPEHKEPRCRDPDQDARSR-------DRVAEVHT 75
E ++ RE+K+R KE E E ++ R + A R D+V H
Sbjct: 127 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW 186
Query: 76 AKESPRGERDRDRQRERRRDAKDR-----------------------------------E 100
++ PR R+R + R+ K+ E
Sbjct: 187 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 246
Query: 101 KEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERK 160
+E+ +E+ E E S S + E+E++ +E + +E + ++ E ER+
Sbjct: 247 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 306
Query: 161 GRSVSKVRSEEK-DEDSERGDEDRE 184
+ V E + D DS +E E
Sbjct: 307 NENHLLVVPESRFDRDSGESEEAEE 331
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 79.3 bits (194), Expect = 2e-14
Identities = 73/302 (24%), Positives = 121/302 (40%), Gaps = 43/302 (14%)
Query: 29 GSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDR 88
GS+ R + + S ++ R R S+ ++ + S R + R
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRS----GSSKSSHSKSRSRSRSGSRSRSKSR 233
Query: 89 QRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVA--------- 139
R + R +EK + K + +SHS GK R K KD+ K + V
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 140 HHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKD 199
H + +R ++ E++G SVS+ RS+EK R + R R SKD
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRG-SVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352
Query: 200 NPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEK 259
K +G +R R+ + R +S +R K E+ K S S G + K+K
Sbjct: 353 --------KRKGRKRSRE--------ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKK 396
Query: 260 RHKEGFHFDDERHQS-----NVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHA 314
D +R QS +V ++ + AK E +RE + GE N G + + S ++
Sbjct: 397 E-------DTDRSQSRSPSRSVSKEREHAKSESSQREGR-GESENAGTNQETRSRSRSNS 448
Query: 315 EN 316
++
Sbjct: 449 KS 450
Score = 74.7 bits (182), Expect = 4e-13
Identities = 63/304 (20%), Positives = 118/304 (38%), Gaps = 23/304 (7%)
Query: 26 QSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEV-----HTAKESP 80
+SG SK + R S + R + +SR E H+A +S
Sbjct: 207 RSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSR 266
Query: 81 RGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAH 140
+D+ ++ + D + K + +H+ KS SR ++R E+++R R
Sbjct: 267 SKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGR----- 321
Query: 141 HNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDN 200
QE RQ R+ KG S S+ RS K +D +G + R R S+ +
Sbjct: 322 ----SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERS 377
Query: 201 PLKYWLYKEEGERRHRKPREPDRDNKH-REKSSTREKREKYSKEKSNSFSDKGEERHKEK 259
++ G +R K + K ++S +R SKE+ ++ S+ + + +
Sbjct: 378 -------RKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
Query: 260 RHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVR 319
G + + + + + + E R R + R+R S R + S + + R
Sbjct: 431 SENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSP-SRSRSR 489
Query: 320 NHGK 323
+H +
Sbjct: 490 SHSR 493
Score = 41.2 bits (95), Expect = 0.005
Identities = 62/292 (21%), Positives = 99/292 (33%), Gaps = 74/292 (25%)
Query: 159 RKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKP 218
R+ RS S+ RS + R R R+ + + G SK + H K
Sbjct: 180 RRRRSYSRSRSHSRSRS-------RSRHSRKSRSRSGSSKSS--------------HSKS 218
Query: 219 REPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQS---- 274
R ++ R S +R K S+ +S S +K KEK R +S
Sbjct: 219 R-----SRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQA 273
Query: 275 --------NVDR-------------KEKSAKDEPRKRESQNG--------EHRNRGASSK 305
NV + K +S E R E + G E R + S+
Sbjct: 274 EEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333
Query: 306 RDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSS-------------VWWKLDQRPGGEET 352
+ + R+ KDK RK EE S K D + G +
Sbjct: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSK- 392
Query: 353 VEIEKEETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREK 404
+ +KE+TD +R+ + + S E + E G+ + + E+R +
Sbjct: 393 -KKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSR 443
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 79.3 bits (194), Expect = 2e-14
Identities = 70/337 (20%), Positives = 154/337 (45%), Gaps = 34/337 (10%)
Query: 2 EPGKRRTKDDTWKADDLRKH----LWAIQSGGSKEERKHREKKLRKESEMDLPE-----H 52
E RR ++ W+ ++ + +W KEE+ R +++ E E + E H
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMW------EKEEKMRRLEEMMWEKEEKIRELEEKMH 387
Query: 53 KEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAE 112
++ + R+ ++ + +++ E +E E RQ E+ R+ +++ +E+ K+ R+ E
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQ---EAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
Query: 113 KSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQET--RDRQLLERAERKGRSVSKV-RS 169
K H + K RE+EK R+ ++E RQ + QE R ++ + E+ + KV R
Sbjct: 445 KIHEQEKIREEEK-RQEQEEMWRQ---EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ 500
Query: 170 EEKDEDSERGDEDRER---------RYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPRE 220
EEK D E ++E R +E K++ + K + + ++E + ++ +
Sbjct: 501 EEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 560
Query: 221 PDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKE 280
+++ R++ RE+ EK ++K + + +E++ +E E+ + +++E
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 281 KSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENL 317
K + E + +E + R +++ Q E +
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 657
Score = 68.6 bits (166), Expect = 3e-11
Identities = 77/441 (17%), Positives = 195/441 (44%), Gaps = 49/441 (11%)
Query: 14 KADDLRKHLWAIQSG-GSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAE 72
+AD L K L ++ + ++ E +L ++ E + +E + + + + +++ +
Sbjct: 266 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE---KIQEWEEKIQEQEEK 322
Query: 73 VHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKE 132
+ +E R + ++ R++E K+ + + +E E E+ R ++ EK+ + R+
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIREL 382
Query: 133 ELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKL 192
E ++ +++ + E K + K+R +EK ++ E +E + RE++
Sbjct: 383 E------------EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 430
Query: 193 QYGDSKDNPLKYWLYKE---EGERRHRKPREPDRDNKHREKSSTREKREKY-SKEKSNSF 248
+ ++ K W +E E E+ + + +++ R++ RE+ E + KEK +
Sbjct: 431 KI---REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487
Query: 249 SDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDG 308
++ K R +E H +E+ + +++EK + E + RE + +++
Sbjct: 488 EKIRKQEEKVWRQEEKMHDQEEKIR---EQEEKMWRQEEKIREQEEKIREQEEKIREQEE 544
Query: 309 TSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARAD 368
+ E + K ++ + EE K+ ++ EE + +KE+
Sbjct: 545 MMQEQEEKMGEQEEKMQEQEKMRRQEE------KIREQ---EEKIREQKEKIR------- 588
Query: 369 AYTASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENE 428
E + + +E + ++ + ++ E + E+ EE Q++++QE + + + E
Sbjct: 589 ------EQEEKIWEQEEKIREQEEMMQEQEEKMWEQ-EEKMCEQEEKMQEQEEKMRRQEE 641
Query: 429 RIGELSLKLFQKRGRTEFEKE 449
++ E ++L Q+ + + +E
Sbjct: 642 KMWEQEVRLRQQEEKMQEHQE 662
Score = 50.1 bits (118), Expect = 1e-05
Identities = 46/212 (21%), Positives = 99/212 (46%), Gaps = 29/212 (13%)
Query: 2 EPGKRRTKDDTWKADDL---RKHLWAIQSGGSKEE--RKHREKKLRKESEMDLPEHK--- 53
E KR+ +++ W+ ++ ++ +W + ++E RK EK R+E +M E K
Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIRE 513
Query: 54 --------EPRCRDPDQDARSRDRVA----EVHTAKESPRGERDRDRQRE---RRRDAKD 98
E + R+ ++ R ++ E+ +E GE++ Q + RR++ K
Sbjct: 514 QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Query: 99 REKE----KLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLL 154
RE+E + KEK RE E+ +++ +E++ +++E + + QE + ++
Sbjct: 574 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633
Query: 155 ERAERKGRSV--SKVRSEEKDEDSERGDEDRE 184
E+ R+ + +VR +++E + E E
Sbjct: 634 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 77.8 bits (190), Expect = 5e-14
Identities = 86/351 (24%), Positives = 136/351 (38%), Gaps = 47/351 (13%)
Query: 6 RRTKDDTWKADDLRKHLWAIQSGGSKEERKHR------EKKLRKESEMDLPEHKEPRCRD 59
RR + W + ++ + S S +ER HR ++ R +S + R R
Sbjct: 348 RRGRSHNWSRNPSKERSHS-HSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRS 406
Query: 60 PDQDARSRDRVAEVHTAKE-----SPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKS 114
P++ AR R R + A++ SP RD R R + A+DR + + K R+ +S
Sbjct: 407 PNK-ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYK-ARDRSRSRSPNKARDHSRS 464
Query: 115 HSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQ-LLERAERKGRSVSKVRSEEKD 173
S K R++ + R KE H+ LG +++R R+ K R + RS K+
Sbjct: 465 RSPNKARDRSRSRSPSKER------DHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518
Query: 174 EDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKP---------REPDRD 224
D R + R R + +D +E R+ R P R P ++
Sbjct: 519 RDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKE 578
Query: 225 NKHREKSSTREKREKYSKEKSNSFSDKGEER--HKEKRH-------KEGFHFDDERHQSN 275
+ R+ S+ E+R+ N S R KEK H KEG H QS
Sbjct: 579 RERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNH-----SQSR 633
Query: 276 VDRKEK--SAKDEPRKRESQNGEHRNRGASSKR-DGTSSQHAENLVRNHGK 323
KE S PR + + R S R +S H+ + + G+
Sbjct: 634 TSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQ 684
Score = 77.8 bits (190), Expect = 5e-14
Identities = 80/312 (25%), Positives = 121/312 (38%), Gaps = 24/312 (7%)
Query: 19 RKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKE 78
R H W S +ER H + E D PR + S ++ + H+
Sbjct: 351 RSHNW---SRNPSKERSHSHSR-SSSKERDHRGSSSPRKESGRSQSGSPNKQRD-HSRSR 405
Query: 79 SPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTV 138
SP RDR R R + A+DR + + K R+ +S S K R++ + R K
Sbjct: 406 SPNKARDRSRSRSPYK-ARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464
Query: 139 AHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSK 198
N + RDR R+ K R S++ S K+ D R + R + +
Sbjct: 465 RSPN----KARDRSR-SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKER 519
Query: 199 DNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKE 258
D+ KE R+ R P NK R++S +R E+ +S S S + + R
Sbjct: 520 DHRRSRSPSKERQRRQSRSP------NKERDRSQSRSPSEEREHRQSRSPSKERDRRRWR 573
Query: 259 KRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLV 318
KE ER QS +E+ R Q+G R R ASSK S +
Sbjct: 574 SPSKE-----RERRQSRSSSEERD-HSRSRSPNKQSGYSRPR-ASSKEKAHSRSRTPSKE 626
Query: 319 RNHGKDKDSRRK 330
NH + + S ++
Sbjct: 627 GNHSQSRTSSKE 638
Score = 61.2 bits (147), Expect = 5e-09
Identities = 72/337 (21%), Positives = 119/337 (35%), Gaps = 44/337 (13%)
Query: 7 RTKDDTWKADDLRKHLWA-----IQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPD 61
R + +WK + R Q G + R H + K + +S R+P
Sbjct: 301 RVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPS 360
Query: 62 QDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDR 121
++ H+ S ERD R+++ R + K R+ +S S K R
Sbjct: 361 KERS--------HSHSRSSSKERDHRGSSSPRKES-GRSQSGSPNKQRDHSRSRSPNKAR 411
Query: 122 EKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDE 181
++ + R K R N +R R + K R S+ RS K D R
Sbjct: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSR-----SPYKARDRSRSRSPNKARDHSRSRS 466
Query: 182 DRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYS 241
+ R R R +D+ L ER HR+ R P ++ + R+ S+ ++R+
Sbjct: 467 PNKARDRSRSRSPSKERDHSQ---LGSPSKERDHRRSRSPSKERQCRQSRSSSKERDH-- 521
Query: 242 KEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRG 301
+S S S + + R +KE DR + + E R EHR
Sbjct: 522 -RRSRSPSKERQRRQSRSPNKER------------DRSQSRSPSEER-------EHRQSR 561
Query: 302 ASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSS 338
+ SK + + R + + S + H S
Sbjct: 562 SPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRS 598
Score = 58.5 bits (140), Expect = 3e-08
Identities = 77/366 (21%), Positives = 122/366 (33%), Gaps = 58/366 (15%)
Query: 30 SKEERKHREKKLRKESEMDLPEH----KEPRCRDPDQDARSRDRVAEVHTAKESPRGERD 85
S E R K + S P+ + PR R+ RV H+ K + R
Sbjct: 258 SPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRS-HSWKRNHSRARS 316
Query: 86 RDR-----QRERRRDAKDREKEKLKEKHR--------------EAEKSHSRGKDREKEKD 126
R R Q R ++ K K + + R E+SHS + KE+D
Sbjct: 317 RTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERD 376
Query: 127 RRA----RKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDED 182
R RKE R N K R S+ RS K D R
Sbjct: 377 HRGSSSPRKESGRSQSGSPN-----------------KQRDHSRSRSPNKARDRSRSRSP 419
Query: 183 RERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSK 242
+ R R R ++D YK R R P + ++ R + R++ S
Sbjct: 420 YKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSP 479
Query: 243 EKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGA 302
K S G KE+ H+ +S KE+ + + S+ +HR +
Sbjct: 480 SKERDHSQLGSPS-KERDHR----------RSRSPSKERQCRQS--RSSSKERDHRRSRS 526
Query: 303 SSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDL 362
SK + N R+ + + + H + S + D+R + E E+ ++
Sbjct: 527 PSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRS 586
Query: 363 ENARAD 368
+ D
Sbjct: 587 SSEERD 592
Score = 53.1 bits (126), Expect = 1e-06
Identities = 58/255 (22%), Positives = 94/255 (36%), Gaps = 41/255 (16%)
Query: 3 PGKRRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQ 62
P K R + + R H Q G +ER HR + KE +CR
Sbjct: 467 PNKARDRSRSRSPSKERDHS---QLGSPSKERDHRRSR---------SPSKERQCRQSRS 514
Query: 63 DARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHR--EAEKSHSRGKD 120
++ RD H SP ER +RR ++ KE+ + + R E+ H + +
Sbjct: 515 SSKERD-----HRRSRSPSKER-------QRRQSRSPNKERDRSQSRSPSEEREHRQSRS 562
Query: 121 REKEKDRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGD 180
KE+DRR + ++ + E RD R+ K S+ R+ K++ R
Sbjct: 563 PSKERDRRRWRSPSKERERRQSRSSSEERDHS-RSRSPNKQSGYSRPRASSKEKAHSRS- 620
Query: 181 EDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKR--E 238
R ++ + S+ + KE + PR PD SS + R
Sbjct: 621 -----RTPSKEGNHSQSRTSS------KESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPS 669
Query: 239 KYSKEKSNSFSDKGE 253
K S ++F G+
Sbjct: 670 KTSSHSPSTFPSGGQ 684
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 77.0 bits (188), Expect = 9e-14
Identities = 104/459 (22%), Positives = 187/459 (40%), Gaps = 48/459 (10%)
Query: 32 EERKHREKKLRKESEMDLPEHKE--PRCRDPDQDARSR---DRVAEVHTAKESPRGERDR 86
E RE++ +K + L KE P D SR + AE T ++ + E +
Sbjct: 98 ERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQ 157
Query: 87 DR-------------QRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARK-- 131
+R Q+ RDA++ +KE KEK E E+ RG E + + +
Sbjct: 158 ERYEIEETETVTKSYQKNDWRDAEENKKED-KEKEEEEEEKPKRGSIGENQVEVMVEEKT 216
Query: 132 -EELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRER 190
E +TV GQ + + E +G + ++ED ER + +R R E
Sbjct: 217 TESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEE 276
Query: 191 KLQYGDSKDNPLKYWLYKEEGERR----HRKPRE-PDRDNKHREKSSTREKREKYSKEKS 245
+ + +D + + E E + R+ RE +R+ E+ E+R++ +E+
Sbjct: 277 RERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEK 336
Query: 246 NSFSDKGEERHKEKR--------HKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEH 297
+ ++ + +EKR +E +ER ++ + +EK AK E +KR Q E
Sbjct: 337 RAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEK-AKVEEQKRNKQLEEK 395
Query: 298 RNRGASSKRDGTS-SQHAENLVRNHGKDKDSR------RKHGHEEGSSVWWKLDQRPGGE 350
++ +K G Q E N K ++ + +K G E+G+ V K ++ E
Sbjct: 396 KHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQ--E 453
Query: 351 ETVEIEKEETDLENARADAYTASCEDDFEDYEDDF-EVCDGDDDESSNEPESREKLEELP 409
+ +KEE E + D F D + F EV + + +++ + E P
Sbjct: 454 DKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRP 513
Query: 410 LAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFEK 448
+ + + A A G+ +L ++RG TE E+
Sbjct: 514 GGRAS--VDTKEAEGAPQVEAGKRLEELRRRRGETESEE 550
Score = 71.2 bits (173), Expect = 5e-12
Identities = 98/419 (23%), Positives = 171/419 (40%), Gaps = 69/419 (16%)
Query: 30 SKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDR- 88
S E+ E K R E+E E +E +QD + D A + +++ ER+R
Sbjct: 252 SHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREA 311
Query: 89 -QRERRRDAKDR---EKEKLKEKHREAEKSHSRGKDREK----------EKDRRARKEEL 134
+RER R+ + R E++++KE+ + A + R K+ EK E+++RA +E
Sbjct: 312 EERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 371
Query: 135 RQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQY 194
R E + R ++ +K++ E+ ++ E G E++ +E KLQ
Sbjct: 372 RARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIE-GKWVNEKKAQEDKLQT 430
Query: 195 GDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEE 254
+ K++GE + K + KREK ++K +F + +
Sbjct: 431 A----------VLKKQGEEKGTK---------------VQAKREKLQEDKP-TFKKEEIK 464
Query: 255 RHKEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHA 314
K K+ KE E +S +DRK+ + +SQNGE +H
Sbjct: 465 DEKIKKDKE----PKEEVKSFMDRKKGFT-----EVKSQNGEFMTH---------KLKHT 506
Query: 315 ENLVRNHG--KDKDSRRKHG--HEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAY 370
EN G D++ G E +L +R G E+ E EK + + A +
Sbjct: 507 ENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALE-- 564
Query: 371 TASCEDDFEDYEDDFEVCDGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENER 429
E+ + E+ +V + ++ E R+ EE + KE E +RA AE +
Sbjct: 565 ---LEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQ 620
Score = 67.0 bits (162), Expect = 9e-11
Identities = 93/436 (21%), Positives = 183/436 (41%), Gaps = 61/436 (13%)
Query: 85 DRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLL 144
D +R+RE RR + RE+ +L+ + +++ ++ +E+ RRAR+E LRQ + L
Sbjct: 3 DFERRRELRR--QKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEES-L 59
Query: 145 GQETRDRQLLER----AERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDN 200
GQ T ++ + E + + + E DE + R R+++LQ +
Sbjct: 60 GQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQK 119
Query: 201 PLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKR-EKYSKEKSNSFS---DKGEERH 256
+ R+ + +N+ EK E R E+Y E++ + + K + R
Sbjct: 120 EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRD 179
Query: 257 KEKRHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAEN 316
E+ KE KEK ++E + + GE++ ++ S +
Sbjct: 180 AEENKKED--------------KEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVV 225
Query: 317 LVRNHGK--DKDSRRKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLENARADAYTASC 374
+ +G+ ++ +++ E+GS D+ E+ E +KE + E AR +A
Sbjct: 226 MSLKNGQISSEEPKQEEEREQGS------DEISHHEKMEEEDKERAEAERARLEAE---- 275
Query: 375 EDDFEDYEDDFEVCD-----------GDDDESSNEPESREKL---EELPLAQKKEIQEIQ 420
E + E D ++ D + E E RE++ E+ +++ I+E +
Sbjct: 276 ERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE 335
Query: 421 RAINAENERIGELSLKLFQKRGRTEFEKEPRTDTNSSPSRASVCGIFVDFASASHRQKSR 480
+ E +RI E + ++R R + E+E R +RA + A ++ R
Sbjct: 336 KRAAEERQRIKEEEKRAAEERQRIK-EEEKRAAEERQRARAE------EEEKAKVEEQKR 388
Query: 481 TQALKQK---MRSTKL 493
+ L++K M+ TK+
Sbjct: 389 NKQLEEKKHAMQETKI 404
Score = 58.2 bits (139), Expect = 4e-08
Identities = 81/410 (19%), Positives = 160/410 (39%), Gaps = 38/410 (9%)
Query: 48 DLPEHKEPRCRDPDQDARSRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEK 107
D +E R + ++ +R+A + R+R R+ + R + +E+E L +
Sbjct: 3 DFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQV 62
Query: 108 HREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRD--RQLLERAERKGRSVS 165
+ E + EE + T + + G + +L R ER+ + +
Sbjct: 63 TDQVEVN----------AQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQ 112
Query: 166 KVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREPDRDN 225
+ +K+ D D R++Q D+ +N K E + + E +
Sbjct: 113 EALERQKEFDPT--ITDASLSLPSRRMQ-NDTAENETTEKEEKSESRQERYEIEETETVT 169
Query: 226 KHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSAKD 285
K +K+ R+ E N DK +E +E++ K G + + + V+ K +++
Sbjct: 170 KSYQKNDWRDAEE-------NKKEDKEKEEEEEEKPKRG-SIGENQVEVMVEEKTTESQE 221
Query: 286 EPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKLDQ 345
E +NG+ +S + + R G D+ S + EE
Sbjct: 222 ETVVMSLKNGQI-----------SSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERA 270
Query: 346 RPGGEETVEIEKEETDL---ENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPESR 402
R EE I+ E+ E AR +A + + E E + ++++ + E R
Sbjct: 271 RLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQR 330
Query: 403 EKLEELPLAQKKE-IQEIQRAINAENERIGELSLKLFQKRGRTEFEKEPR 451
K EE A++++ I+E ++ E +RI E + ++R R E+E +
Sbjct: 331 IKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEK 380
Score = 42.4 bits (98), Expect = 0.002
Identities = 57/303 (18%), Positives = 121/303 (39%), Gaps = 15/303 (4%)
Query: 6 RRTKDDTWKADDLRKHLWAIQSGGSKEERKHREKKLRKESEMDLPEHKEPRCRDPDQDAR 65
R +++ K ++ +++ + + +E K + +K+ ++ E K+ + D Q A
Sbjct: 374 RAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQ-EDKLQTAV 432
Query: 66 SRDRVAEVHTAKESPRGERDRDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEK 125
+ + E T ++ R + D+ ++ + KD + +K KE E + R K + K
Sbjct: 433 LKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVK 492
Query: 126 DRRARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRER 185
+ E + + H R ++ E +G + E +R +E R R
Sbjct: 493 SQNG--EFMTHKLKHTENTFSRPGGRASVDTKEAEGAP--------QVEAGKRLEELRRR 542
Query: 186 RYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPRE--PDRDNKHREKSSTREKREKYSKE 243
R ++ K + L EE +++ + R+ + + + +++ + R+ RE+ K
Sbjct: 543 RGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKR 602
Query: 244 KSNSFSDKGEERHKEKRHK--EGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRG 301
+ ++ EKR K E DD++ K S K E R ++ G
Sbjct: 603 RLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSG 662
Query: 302 ASS 304
S
Sbjct: 663 VKS 665
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 76.6 bits (187), Expect = 1e-13
Identities = 81/297 (27%), Positives = 134/297 (45%), Gaps = 35/297 (11%)
Query: 30 SKEERKHREKKLRKESEMDLPEHKEP-------RCRDPDQD-ARSRDRVAEVHTAKESPR 81
SKEERK R + +E + D P R RD + +RSR R +E
Sbjct: 16 SKEERK-RSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRH 74
Query: 82 GERDRDRQRERRRDAKDREKE--KLKEKHREAEKSHSRGKDREKEKDRRARKEEL----- 134
ER+RD++R+R + +DR+K+ + + + + S RGKD + KDR ++K+E
Sbjct: 75 KERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGD 134
Query: 135 RQTVAHHNLLGQETRDRQLLERAERKGRSVSKV-RSEEKDEDSERGDEDRERRYRERKLQ 193
++ A L + ++ E AE K + +SK R E + ++ E+R+R E + +
Sbjct: 135 KKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKK 194
Query: 194 YGDSKDNPLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGE 253
+D K +E ERR R+ R N + ++ E R+K +EK DK +
Sbjct: 195 RKQFQDLGRKMLEDPQERERRERRERMERETNGNEDE----EGRQKIREEK-----DKSK 245
Query: 254 ERH--KE------KRHKEGFHFDDERHQSNVDRKEKSAKD-EPRKRESQNGEHRNRG 301
E H KE K+ + H +D + D E ++ D P +E + RG
Sbjct: 246 ELHAIKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSIDYNPLYKERHQVQLLGRG 302
Score = 72.0 bits (175), Expect = 3e-12
Identities = 64/263 (24%), Positives = 111/263 (42%), Gaps = 32/263 (12%)
Query: 63 DARSRDRVAEVHTAKESPRGERDRDRQRERRRD-AKDREKEKLKEKHREAEKSHSRG--- 118
D + RD K S +R+RDR R+R+ +KDR++ + +++ R +S SR
Sbjct: 7 DKKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSK 66
Query: 119 --------KDREKEKDR-RARKEELRQTVAHHNLLGQETRDRQLLERAERKGRSVSKVRS 169
K+RE++K+R R +K+ R H + R R L K K R
Sbjct: 67 SAERERRHKERERDKERDRNKKDRDRDKDGHRR---DKDRKRSSLSPGRGKDFKSRKDRD 123
Query: 170 EEKDEDSERGDED--------RERRYRERKLQYGDSKDNPLKYWLYKEEGERRHRKPREP 221
+KDE+ E GD+ E +++ + ++K +L K E E K R+
Sbjct: 124 SKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPK----FLSKAEREAEALKRRQQ 179
Query: 222 DRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHK----EGFHFDDERHQSNVD 277
+ + + R R+KR+++ D E +E+R + + D+E Q +
Sbjct: 180 EVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIRE 239
Query: 278 RKEKSAKDEPRKRESQNGEHRNR 300
K+KS + K G + R
Sbjct: 240 EKDKSKELHAIKERYLGGIKKRR 262
Score = 65.5 bits (158), Expect = 3e-10
Identities = 60/264 (22%), Positives = 118/264 (44%), Gaps = 39/264 (14%)
Query: 86 RDRQRERRRDAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLG 145
+DR ++ + R + +E+ R+ ++ S KDR++ + R R+ G
Sbjct: 9 KDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRG------------G 56
Query: 146 QETRDRQLLERAERKGRSVSKVRSEEKDEDSERGDEDRE--RRYRERK---LQYGDSKDN 200
+R R + AER+ R + R +E+D + + D D++ RR ++RK L G KD
Sbjct: 57 SRSRSRSRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKD- 115
Query: 201 PLKYWLYKEEGERRHRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSD-KGEERHKEK 259
+K +R +K E + +K + K+ E +K+K+ ++ K + K +
Sbjct: 116 ------FKSRKDRDSKKDEEDEHGDK-KPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAE 168
Query: 260 RHKEGFHFDDERHQSNVDRKEKSAKDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVR 319
R E +R Q V+ +++ ++E +KR+ + ++ G D + E R
Sbjct: 169 REAEAL----KRRQQEVEERQRMLEEERKKRK----QFQDLGRKMLEDPQERERRERRER 220
Query: 320 -----NHGKDKDSRRKHGHEEGSS 338
N +D++ R+K E+ S
Sbjct: 221 MERETNGNEDEEGRQKIREEKDKS 244
Score = 49.3 bits (116), Expect = 2e-05
Identities = 57/276 (20%), Positives = 112/276 (40%), Gaps = 58/276 (21%)
Query: 95 DAKDREKEKLKEKHREAEKSHSRGKDREKEKDRRARKEELRQTVAHHNLLGQETRDRQLL 154
D KDR+ KE E+ SR DRE+++DR + + H + RDR
Sbjct: 7 DKKDRDASPSKE-----ERKRSRTPDRERDRDRDRKSSPSKDRKRHRS------RDR--- 52
Query: 155 ERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGERR 214
R+G S S+ RS K + RERR++ER+
Sbjct: 53 ----RRGGSRSRSRSRSKSAE-------RERRHKERE----------------------- 78
Query: 215 HRKPREPDRDNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQS 274
+ +E DR+ K R++ +R+K K +S S + K ++ ++ +++ H
Sbjct: 79 --RDKERDRNKKDRDRDKDGHRRDK--DRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGD 134
Query: 275 NVDRKEKSAKDE--PRKRESQNGEHRNRGAS-SKRDGTSSQHAENLVRNHGK---DKDSR 328
+ + + +E +K+ + E + + S ++R+ + + + V + ++ +
Sbjct: 135 KKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKK 194
Query: 329 RKHGHEEGSSVWWKLDQRPGGEETVEIEKEETDLEN 364
RK + G + +R E +E+E E+
Sbjct: 195 RKQFQDLGRKMLEDPQERERRERRERMERETNGNED 230
Score = 43.5 bits (101), Expect = 0.001
Identities = 56/246 (22%), Positives = 106/246 (43%), Gaps = 36/246 (14%)
Query: 224 DNKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEGFHFDDERHQSNVDRKEKSA 283
D K R+ S ++E+R K + D+ ER +++ K D +RH+S DR+ +
Sbjct: 7 DKKDRDASPSKEER------KRSRTPDR--ERDRDRDRKSSPSKDRKRHRSR-DRRRGGS 57
Query: 284 KDEPRKRESQNGEHRNRGASSKRDGTSSQHAENLVRNHGKDKDSRRKHGHEEGSSVWWKL 343
+ R R S++ E R +RD + + ++ +DKD R+ + SS+
Sbjct: 58 RSRSRSR-SKSAERERRHKERERD----KERDRNKKDRDRDKDGHRRDKDRKRSSL---- 108
Query: 344 DQRPGGEETVEIEKE---ETDLENARADAYTASCEDDFEDYEDDFEVCDGDDDESSNEPE 400
PG + + K+ + D E+ D + E+ + ++E+ +P+
Sbjct: 109 --SPGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKA----EEEAEAKPK 162
Query: 401 SREKLEELPLAQKK---EIQEIQRAINAENER------IGELSLKLFQKRGRTEFEKEPR 451
K E A K+ E++E QR + E ++ +G L+ Q+R R E +
Sbjct: 163 FLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERME 222
Query: 452 TDTNSS 457
+TN +
Sbjct: 223 RETNGN 228
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,739,997
Number of Sequences: 37866
Number of extensions: 2152232
Number of successful extensions: 30744
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 457
Number of HSP's successfully gapped in prelim test: 953
Number of HSP's that attempted gapping in prelim test: 9794
Number of HSP's gapped (non-prelim): 8291
length of query: 1066
length of database: 18,247,518
effective HSP length: 113
effective length of query: 953
effective length of database: 13,968,660
effective search space: 13312132980
effective search space used: 13312132980
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.