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Search of human proteins with 155029548
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|155029548 phosphofurin acidic cluster sorting protein 2
isoform 1 [Homo sapiens]
(893 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|155029548 phosphofurin acidic cluster sorting protein 2 isofo... 1773 0.0
gi|155029546 phosphofurin acidic cluster sorting protein 2 isofo... 1760 0.0
gi|30089916 phosphofurin acidic cluster sorting protein 1 [Homo ... 979 0.0
gi|217330641 IWS1 homolog [Homo sapiens] 47 1e-04
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 43 0.001
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 42 0.003
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 42 0.003
gi|73858561 proline/serine-rich coiled-coil 1 isoform a [Homo sa... 40 0.007
gi|73858559 proline/serine-rich coiled-coil 1 isoform c [Homo sa... 40 0.007
gi|52630338 proline/serine-rich coiled-coil 1 isoform b [Homo sa... 40 0.007
gi|14249168 proline/serine-rich coiled-coil 1 isoform a [Homo sa... 40 0.007
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 40 0.007
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 40 0.007
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 40 0.007
gi|56118310 nuclear casein kinase and cyclin-dependent kinase su... 40 0.010
gi|61742814 coiled-coil and C2 domain containing 1B [Homo sapiens] 40 0.010
gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens] 40 0.013
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 40 0.013
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 39 0.016
gi|239754138 PREDICTED: hypothetical protein [Homo sapiens] 39 0.016
gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo ... 39 0.016
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 39 0.016
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 39 0.022
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 39 0.022
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 39 0.022
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 39 0.022
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 39 0.022
gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo s... 39 0.028
gi|22547121 tumor necrosis factor receptor superfamily, member 1... 38 0.037
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 38 0.048
>gi|155029548 phosphofurin acidic cluster sorting protein 2 isoform
1 [Homo sapiens]
Length = 893
Score = 1773 bits (4592), Expect = 0.0
Identities = 893/893 (100%), Positives = 893/893 (100%)
Query: 1 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 60
MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI
Sbjct: 1 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 60
Query: 61 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 120
SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR
Sbjct: 61 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 120
Query: 121 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 180
YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID
Sbjct: 121 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 180
Query: 181 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV 240
HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV
Sbjct: 181 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV 240
Query: 241 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 300
RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD
Sbjct: 241 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 300
Query: 301 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 360
SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL
Sbjct: 301 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 360
Query: 361 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP 420
GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP
Sbjct: 361 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP 420
Query: 421 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ 480
STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ
Sbjct: 421 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ 480
Query: 481 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ 540
LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ
Sbjct: 481 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ 540
Query: 541 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR 600
RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR
Sbjct: 541 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR 600
Query: 601 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM 660
YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM
Sbjct: 601 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM 660
Query: 661 LTYKQKSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAA 720
LTYKQKSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAA
Sbjct: 661 LTYKQKSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAA 720
Query: 721 KEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTL 780
KEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTL
Sbjct: 721 KEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTL 780
Query: 781 KCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGIS 840
KCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGIS
Sbjct: 781 KCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGIS 840
Query: 841 RLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHSKATF 893
RLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHSKATF
Sbjct: 841 RLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHSKATF 893
>gi|155029546 phosphofurin acidic cluster sorting protein 2 isoform
2 [Homo sapiens]
Length = 889
Score = 1760 bits (4559), Expect = 0.0
Identities = 889/893 (99%), Positives = 889/893 (99%), Gaps = 4/893 (0%)
Query: 1 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 60
MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI
Sbjct: 1 MAERGRLGLPGAPGALNTPVPMNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELI 60
Query: 61 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 120
SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR
Sbjct: 61 SVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKR 120
Query: 121 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 180
YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID
Sbjct: 121 YKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPID 180
Query: 181 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV 240
HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV
Sbjct: 181 HEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIV 240
Query: 241 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 300
RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD
Sbjct: 241 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 300
Query: 301 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 360
SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL
Sbjct: 301 SGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSL 360
Query: 361 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP 420
GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP
Sbjct: 361 GGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIP 420
Query: 421 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQ 480
STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARS QLQIPRKTVYDQ
Sbjct: 421 STRSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARS----QLQIPRKTVYDQ 476
Query: 481 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ 540
LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ
Sbjct: 477 LNHILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQ 536
Query: 541 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR 600
RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR
Sbjct: 537 RYCNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVAR 596
Query: 601 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM 660
YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM
Sbjct: 597 YLGSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAM 656
Query: 661 LTYKQKSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAA 720
LTYKQKSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAA
Sbjct: 657 LTYKQKSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAA 716
Query: 721 KEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTL 780
KEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTL
Sbjct: 717 KEASPTPPSSPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTL 776
Query: 781 KCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGIS 840
KCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGIS
Sbjct: 777 KCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGIS 836
Query: 841 RLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHSKATF 893
RLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHSKATF
Sbjct: 837 RLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHSKATF 889
>gi|30089916 phosphofurin acidic cluster sorting protein 1 [Homo
sapiens]
Length = 963
Score = 979 bits (2531), Expect = 0.0
Identities = 529/895 (59%), Positives = 660/895 (73%), Gaps = 30/895 (3%)
Query: 10 PGAPGALNTPVP--MNLFATWEVDGSSPSCVPRLCSLTLKKLVVFKELEKELISVVIAVK 67
PG PG TP P MNL+ATWEVD SS SCVPRL SLTLKKLV+ KE++K+L SVVIAVK
Sbjct: 87 PGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVK 146
Query: 68 MQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPHFLKREGNKLQIMLQRRKRYKNRTIL 127
+QGSKRILRS+EIVLP SG VET+L LTFSLQYPHFLKR+ NKLQIMLQRRKRYKNRTIL
Sbjct: 147 LQGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTIL 206
Query: 128 GYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSSQPIDHEDSTMQ 187
GYKTLA G I+MAEVMQHP+EG VL L S++K+ V AEI I SLSSQPIDHE +
Sbjct: 207 GYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSK 266
Query: 188 AGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIVRTTSMTR 247
++ DNYSEEE ESFSSEQE SDD + GQDL +D D+ K KK RR + T+++TR
Sbjct: 267 LSDRSPDIDNYSEEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITR 326
Query: 248 QQNFKQKVVALLRRFKVSDEV-LDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSDSGPDME 306
Q N KQK VALL+RFKVSDEV E E I E EEDLD LYD+L+M +PSDSGP+ME
Sbjct: 327 QPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPSDSGPEME 386
Query: 307 DDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARS-HKEPPSPADVP--EKTRSLGGR 363
+ +S+LSTPKPKL+P+FEG+S SSSQTEIGS++S S K+ SP ++ EK +S +
Sbjct: 387 ETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIK 446
Query: 364 QPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIPS-T 422
DS+++T L + + +AST V E++ + +KT+ S +
Sbjct: 447 NQDDSLTETDTLEI---------TDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPS 497
Query: 423 RSEGKQAGRRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQVQLQIPRKTVYDQLN 482
+ EG R+ RST LKERQ ++P +ER NS D+ER PD L QIPRK VYDQLN
Sbjct: 498 KVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPD----LGHSTQIPRKVVYDQLN 553
Query: 483 HILISDDQLPENIILVNTSDWQGQFLSDVLQRHTLPVVCTCSPADVQAAFSTIVSRIQRY 542
IL+SD LPEN+ILVNT+DWQGQ+++++LQ PVVCTCS +VQA S +++RIQRY
Sbjct: 554 QILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRY 613
Query: 543 CNCNSQPPTPVKIAVAGAQHYLSAILRLFVEQLSHKTPDWLGYMRFLVIPLGSHPVARYL 602
CNCNS P PVK+A G Q YLS+ILR FV+ L++KT DWLGYMRFL+IPLGSHPVA+YL
Sbjct: 614 CNCNSSMPRPVKVAAVGGQSYLSSILRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYL 673
Query: 603 GSVDYRYNNFFQDLAWRDLFNKLEAQSAVQDTPDIVSRITQYIAGANCAHQLPIAEAMLT 662
GSVD +Y++ F D WRDLF++ ++ V + D+ R+ QY+ GA HQLP+AEAMLT
Sbjct: 674 GSVDSKYSSSFLDSGWRDLFSR--SEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEAMLT 731
Query: 663 YKQKSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKE 722
+ K PDE+S QKFIPF+GVVKVG+VE S +T+GD DD+ S++PPS+S +++
Sbjct: 732 CRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRD 791
Query: 723 ASPTPPSSPSVSGGLS---SPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNT 779
A+ TPPSSPS+S L+ SP+ G +++GLQVDYW P +R+R+ +K+D +KNT
Sbjct: 792 ATATPPSSPSMSSALAIVGSPNSPYG-DVIGLQVDYW-LGHPGERRREGDKRDAS-SKNT 848
Query: 780 LKCTFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKV--MFLPKKAKDKDVESKSQCIE 837
LK FRS+QVSRLP SGEA + TM+MTVVTKEKNKKV +FL KK ++K+V+SKSQ IE
Sbjct: 849 LKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIE 908
Query: 838 GISRLICTARQQQNMLRVLIDGVECSDVKFFQLAAQWSSHVKHFPICIFGHSKAT 892
GISRLIC+A+QQQ MLRV IDGVE SD+KFFQLAAQW +HVKHFP+ +F SKAT
Sbjct: 909 GISRLICSAKQQQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKAT 963
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 46.6 bits (109), Expect = 1e-04
Identities = 66/289 (22%), Positives = 115/289 (39%), Gaps = 37/289 (12%)
Query: 179 IDHEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFD--VGKPKKQR 236
++ DS + + K +D+ SEE E +S+ E D G D + ++ G +
Sbjct: 77 LNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENE 136
Query: 237 RSIVRTTSMTRQQNF-----KQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYD 291
+ S + ++ + L++ SD + P I ++E + +
Sbjct: 137 ELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKP--QISDSESEEPPRHQ 194
Query: 292 TLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSA--RSHKEPPS 349
D E+ P M D +S PKP++ S S++E H A ++E P
Sbjct: 195 ASDSENEEPPKPRMSDSESE-ELPKPQV---------SDSESEEPPRHQASDSENEELPK 244
Query: 350 PADVPEKTRSLGGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSG 409
P ++ Q SDS ++ +P PR + ED P +AS D E L P
Sbjct: 245 PRISDSESEDPPRHQASDSENEE----LPKPRISDSESEDPPRNQAS--DSENEEL-PKP 297
Query: 410 RITKTESLVIPSTRSEGKQAGRRGRS-TSLKERQAARPQNERANSLDNE 457
R++ +E SEG Q G S T R +P+++ + +N+
Sbjct: 298 RVSDSE--------SEGPQKGPASDSETEDASRHKQKPESDDDSDRENK 338
Score = 35.4 bits (80), Expect = 0.24
Identities = 32/148 (21%), Positives = 58/148 (39%), Gaps = 15/148 (10%)
Query: 328 HSSSQTEIGSIHSARSHKEPPSPADVPEKTRSLGGRQPSDSVSDTVALGVPGPREHPGQP 387
H +S +EI + + + A P+ + S P SD+ P PR +
Sbjct: 154 HPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSES 213
Query: 388 EDSPEAEASTLDVFTERLPPSGRITKTESLVIPSTR---SEGKQAGRRGRSTS------- 437
E+ P+ + S + PP + + +E+ +P R SE + R S S
Sbjct: 214 EELPKPQVSDSE---SEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPK 270
Query: 438 --LKERQAARPQNERANSLDNERCPDAR 463
+ + ++ P +A+ +NE P R
Sbjct: 271 PRISDSESEDPPRNQASDSENEELPKPR 298
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 43.1 bits (100), Expect = 0.001
Identities = 65/322 (20%), Positives = 122/322 (37%), Gaps = 43/322 (13%)
Query: 181 HEDSTMQAGPKAKSTDNYSEEEYESF--SSEQEASDDAVQGQDLDEDDFDVGKPKKQRRS 238
H+ Q G + + +EEY +E+E ++ + + + + ++ +P ++
Sbjct: 1469 HKYEMPQYGSRRRLLPPAGQEEYGEVVGEAEEEYEEEEEEPKKIKKPKVEIREPSEEEEV 1528
Query: 239 IVR---------TTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLL 289
+V T + ++ + +R ++D E + + E EED D L
Sbjct: 1529 VVTIEKPPAAEPTYTTWKRARIFPMIFKKVRGLADKRGIVDLEGEEWQRRLE-EEDKDYL 1587
Query: 290 YDTLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYF--------EGLSHSSSQTEIGSIHSA 341
TLD E ++S + E++ S T + F E S + S+ E S +
Sbjct: 1588 KLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEEESESETPSEEEESSTPES 1647
Query: 342 RSHKEPPSPADVPEKTRSLGGRQPS-DSVSDTVALGVPGPREHPGQPEDSPEAEASTLDV 400
+ S + K L R+P + V + V G +E P + + P+ E
Sbjct: 1648 EESESTESEGEKARKNIVLARRRPMVEEVKE-----VKGRKEEPQEEQKEPKMEEEEHSE 1702
Query: 401 FTERLP-PSGRITKTESLVIPSTRS----------EGKQAGRRGRSTSLKERQAARPQN- 448
E P P T E+ IP S E ++ G S+S E Q+ P
Sbjct: 1703 EEESGPAPVEESTDPEAQDIPEEGSAESASVEGGVESEEESESGSSSSSSESQSGGPWGY 1762
Query: 449 -----ERANSLDNERCPDARSQ 465
+R+ + + ++ P A S+
Sbjct: 1763 QVPAYDRSKNANQKKSPGANSE 1784
>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
Length = 699
Score = 41.6 bits (96), Expect = 0.003
Identities = 73/343 (21%), Positives = 128/343 (37%), Gaps = 43/343 (12%)
Query: 136 SISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSS-QPIDHEDSTMQAGPKAKS 194
S+ E++Q +G + S K+A + +E + + QP +++ +T + +
Sbjct: 198 SVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERH 257
Query: 195 TDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIVRTTSMTRQQNFKQK 254
+ Y E SE S+D G D + TT ++ +
Sbjct: 258 PEKYQGEAASGCESETSVSEDC-SGLSSQSD--------------ILTTQ--QRDTMQHN 300
Query: 255 VVALLRRFKVSDEVLDSE-QDPAEHIPEAEEDLDLLYDTLDMEHPSDSGPDMEDDDSVLS 313
++ L + + VL+ P+ P D L D + P+ + VL+
Sbjct: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRN--------PEQSTSEKVLT 352
Query: 314 TPKPKLRPYF---EGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSLGGRQPSDSVS 370
+ K P EGLS + + E+ + S +KEP P K SL R S S
Sbjct: 353 SQKSSEYPISQNPEGLS--ADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCS 410
Query: 371 DTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIPSTRSEGKQAG 430
++ R +P Q E +DV ++L SG TE+ +P EG
Sbjct: 411 GSLQ-----NRNYPSQEE-----LIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYL 460
Query: 431 RRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQV-QLQI 472
G S + ++ ++ S P + S L+V QL++
Sbjct: 461 ESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKV 503
>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
Length = 759
Score = 41.6 bits (96), Expect = 0.003
Identities = 73/343 (21%), Positives = 128/343 (37%), Gaps = 43/343 (12%)
Query: 136 SISMAEVMQHPSEGGQVLSLCSSIKEAPVKAAEIWIASLSS-QPIDHEDSTMQAGPKAKS 194
S+ E++Q +G + S K+A + +E + + QP +++ +T + +
Sbjct: 198 SVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERH 257
Query: 195 TDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIVRTTSMTRQQNFKQK 254
+ Y E SE S+D G D + TT ++ +
Sbjct: 258 PEKYQGEAASGCESETSVSEDC-SGLSSQSD--------------ILTTQ--QRDTMQHN 300
Query: 255 VVALLRRFKVSDEVLDSE-QDPAEHIPEAEEDLDLLYDTLDMEHPSDSGPDMEDDDSVLS 313
++ L + + VL+ P+ P D L D + P+ + VL+
Sbjct: 301 LIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRN--------PEQSTSEKVLT 352
Query: 314 TPKPKLRPYF---EGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSLGGRQPSDSVS 370
+ K P EGLS + + E+ + S +KEP P K SL R S S
Sbjct: 353 SQKSSEYPISQNPEGLS--ADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCS 410
Query: 371 DTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIPSTRSEGKQAG 430
++ R +P Q E +DV ++L SG TE+ +P EG
Sbjct: 411 GSLQ-----NRNYPSQEE-----LIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYL 460
Query: 431 RRGRSTSLKERQAARPQNERANSLDNERCPDARSQLQV-QLQI 472
G S + ++ ++ S P + S L+V QL++
Sbjct: 461 ESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKV 503
>gi|73858561 proline/serine-rich coiled-coil 1 isoform a [Homo
sapiens]
Length = 333
Score = 40.4 bits (93), Expect = 0.007
Identities = 52/198 (26%), Positives = 80/198 (40%), Gaps = 28/198 (14%)
Query: 281 EAEEDLDLLYD-TLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIG-SI 338
+ EED+ + D TLD S S E+D +VL TP+ LR GLSH S + +
Sbjct: 3 DLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLR---RGLSHRSDPNAVAPAP 59
Query: 339 HSARSHKEPPSP---ADVPEKTRSLGGRQPSDSVSDTVALG--------VPGPREHPGQP 387
R P SP ++ ++ L + ++ D + G P PR
Sbjct: 60 QGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVL 119
Query: 388 EDSPEAE-ASTLDVFTERLPPSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQAARP 446
+DSP + T++ T R T + S + P RS R+G +L+ RP
Sbjct: 120 KDSPVRDLLPTVNSLT-------RSTPSPSSLTPRLRSN----DRKGSVRALRATSGKRP 168
Query: 447 QNERANSLDNERCPDARS 464
N + S P ++S
Sbjct: 169 SNMKRESPTCNLFPASKS 186
>gi|73858559 proline/serine-rich coiled-coil 1 isoform c [Homo
sapiens]
Length = 363
Score = 40.4 bits (93), Expect = 0.007
Identities = 52/198 (26%), Positives = 80/198 (40%), Gaps = 28/198 (14%)
Query: 281 EAEEDLDLLYD-TLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIG-SI 338
+ EED+ + D TLD S S E+D +VL TP+ LR GLSH S + +
Sbjct: 3 DLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLR---RGLSHRSDPNAVAPAP 59
Query: 339 HSARSHKEPPSP---ADVPEKTRSLGGRQPSDSVSDTVALG--------VPGPREHPGQP 387
R P SP ++ ++ L + ++ D + G P PR
Sbjct: 60 QGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVL 119
Query: 388 EDSPEAE-ASTLDVFTERLPPSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQAARP 446
+DSP + T++ T R T + S + P RS R+G +L+ RP
Sbjct: 120 KDSPVRDLLPTVNSLT-------RSTPSPSSLTPRLRSN----DRKGSVRALRATSGKRP 168
Query: 447 QNERANSLDNERCPDARS 464
N + S P ++S
Sbjct: 169 SNMKRESPTCNLFPASKS 186
>gi|52630338 proline/serine-rich coiled-coil 1 isoform b [Homo
sapiens]
Length = 310
Score = 40.4 bits (93), Expect = 0.007
Identities = 52/198 (26%), Positives = 80/198 (40%), Gaps = 28/198 (14%)
Query: 281 EAEEDLDLLYD-TLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIG-SI 338
+ EED+ + D TLD S S E+D +VL TP+ LR GLSH S + +
Sbjct: 3 DLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLR---RGLSHRSDPNAVAPAP 59
Query: 339 HSARSHKEPPSP---ADVPEKTRSLGGRQPSDSVSDTVALG--------VPGPREHPGQP 387
R P SP ++ ++ L + ++ D + G P PR
Sbjct: 60 QGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVL 119
Query: 388 EDSPEAE-ASTLDVFTERLPPSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQAARP 446
+DSP + T++ T R T + S + P RS R+G +L+ RP
Sbjct: 120 KDSPVRDLLPTVNSLT-------RSTPSPSSLTPRLRSN----DRKGSVRALRATSGKRP 168
Query: 447 QNERANSLDNERCPDARS 464
N + S P ++S
Sbjct: 169 SNMKRESPTCNLFPASKS 186
>gi|14249168 proline/serine-rich coiled-coil 1 isoform a [Homo
sapiens]
Length = 333
Score = 40.4 bits (93), Expect = 0.007
Identities = 52/198 (26%), Positives = 80/198 (40%), Gaps = 28/198 (14%)
Query: 281 EAEEDLDLLYD-TLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIG-SI 338
+ EED+ + D TLD S S E+D +VL TP+ LR GLSH S + +
Sbjct: 3 DLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLR---RGLSHRSDPNAVAPAP 59
Query: 339 HSARSHKEPPSP---ADVPEKTRSLGGRQPSDSVSDTVALG--------VPGPREHPGQP 387
R P SP ++ ++ L + ++ D + G P PR
Sbjct: 60 QGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVL 119
Query: 388 EDSPEAE-ASTLDVFTERLPPSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQAARP 446
+DSP + T++ T R T + S + P RS R+G +L+ RP
Sbjct: 120 KDSPVRDLLPTVNSLT-------RSTPSPSSLTPRLRSN----DRKGSVRALRATSGKRP 168
Query: 447 QNERANSLDNERCPDARS 464
N + S P ++S
Sbjct: 169 SNMKRESPTCNLFPASKS 186
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 40.4 bits (93), Expect = 0.007
Identities = 41/190 (21%), Positives = 82/190 (43%), Gaps = 9/190 (4%)
Query: 148 EGGQVLSLCSSIKEAPVK--AAEIWIASLSSQPIDHEDSTMQAGPKAKSTDNYSEEEYES 205
E ++LS ++ +++P K + ++ S S+P+ E + K S + EE+ E
Sbjct: 1021 EEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEE 1080
Query: 206 FSSEQEASDDAVQGQDLDEDDFDVG-KPKKQRRSIVRTTSMTRQQNFKQKVVALLRRFKV 264
E+E +D + ++ +E++ + + R + ++ ++ R++ F K +R ++
Sbjct: 1081 EEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRI 1140
Query: 265 SDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYFE 324
+ V E I E E L+ +D D E P + + KP LR F+
Sbjct: 1141 NSSV------TTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQ 1194
Query: 325 GLSHSSSQTE 334
QTE
Sbjct: 1195 HQPGKKRQTE 1204
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 40.4 bits (93), Expect = 0.007
Identities = 55/207 (26%), Positives = 87/207 (42%), Gaps = 40/207 (19%)
Query: 295 MEHPSDSGPDM-----EDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPS 349
+E P D P M E+DD + + R S+ + ++ S R K+P S
Sbjct: 545 IEKPVDPPPFMFKPVKEEDDGLSGKHSMRTR---------RSRGSMSTLRSGRK-KQPAS 594
Query: 350 P----ADVPEKTRSLGGRQPS-------DSVSDTVALGVPGPREHPGQPEDSPEAEASTL 398
P + + E RS G PS DS ++TV +E P S + + +
Sbjct: 595 PDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKV 654
Query: 399 DVFTERLP-PSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQAARP----QNERANS 453
TE S + TKT+ + P++ SEG+ G S S+ + ++ P Q+ R+ S
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGE--GESSDSRSVNDEGSSDPKDIDQDNRSTS 712
Query: 454 ------LDNERCPDARSQLQ-VQLQIP 473
DNE D+ +Q Q +Q Q P
Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPP 739
Score = 30.4 bits (67), Expect = 7.7
Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 690 PSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPPSSPS 732
PSSA G P + + ++ PP SP A +A P P +P+
Sbjct: 751 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA-PNQPQAPT 792
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 40.4 bits (93), Expect = 0.007
Identities = 55/207 (26%), Positives = 87/207 (42%), Gaps = 40/207 (19%)
Query: 295 MEHPSDSGPDM-----EDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPS 349
+E P D P M E+DD + + R S+ + ++ S R K+P S
Sbjct: 545 IEKPVDPPPFMFKPVKEEDDGLSGKHSMRTR---------RSRGSMSTLRSGRK-KQPAS 594
Query: 350 P----ADVPEKTRSLGGRQPS-------DSVSDTVALGVPGPREHPGQPEDSPEAEASTL 398
P + + E RS G PS DS ++TV +E P S + + +
Sbjct: 595 PDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKV 654
Query: 399 DVFTERLP-PSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQAARP----QNERANS 453
TE S + TKT+ + P++ SEG+ G S S+ + ++ P Q+ R+ S
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGE--GESSDSRSVNDEGSSDPKDIDQDNRSTS 712
Query: 454 ------LDNERCPDARSQLQ-VQLQIP 473
DNE D+ +Q Q +Q Q P
Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPP 739
Score = 30.4 bits (67), Expect = 7.7
Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 690 PSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPPSSPS 732
PSSA G P + + ++ PP SP A +A P P +P+
Sbjct: 751 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA-PNQPQAPT 792
>gi|56118310 nuclear casein kinase and cyclin-dependent kinase
substrate 1 [Homo sapiens]
Length = 243
Score = 40.0 bits (92), Expect = 0.010
Identities = 50/226 (22%), Positives = 77/226 (34%), Gaps = 37/226 (16%)
Query: 182 EDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQGQDLD----EDDFDVGKPKKQRR 237
ED +GP K + E S + + +D+ +D D +DD + + +
Sbjct: 24 EDYGRDSGPPTKKIRSSPREAKNKRRSGKNSQEDSEDSEDKDVKTKKDDSHSAEDSEDEK 83
Query: 238 SIVRTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEH 297
+ RQ K + R + D + EQ+ + P E+D
Sbjct: 84 EDHKNVRQQRQA--ASKAASKQREMLMEDVGSEEEQEEEDEAPFQEKDSG---------- 131
Query: 298 PSDSGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSP------A 351
SD MEDDD Y G S ++ + R K+ P P
Sbjct: 132 -SDEDFLMEDDDD---------SDY--GSSKKKNKKMVKKSKPERKEKKMPKPRLKATVT 179
Query: 352 DVPEKTRSLGGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEAST 397
P K + GR + S P P+E +PE PE + ST
Sbjct: 180 PSPVKGKGKVGRPTASKASKEKT---PSPKEEDEEPESPPEKKTST 222
Score = 30.8 bits (68), Expect = 5.9
Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 12/82 (14%)
Query: 180 DHEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASD---------DAVQGQDL---DEDDF 227
DH++ Q +K+ E E SE+E + D+ +D D+DD
Sbjct: 85 DHKNVRQQRQAASKAASKQREMLMEDVGSEEEQEEEDEAPFQEKDSGSDEDFLMEDDDDS 144
Query: 228 DVGKPKKQRRSIVRTTSMTRQQ 249
D G KK+ + +V+ + R++
Sbjct: 145 DYGSSKKKNKKMVKKSKPERKE 166
>gi|61742814 coiled-coil and C2 domain containing 1B [Homo sapiens]
Length = 858
Score = 40.0 bits (92), Expect = 0.010
Identities = 33/96 (34%), Positives = 44/96 (45%), Gaps = 13/96 (13%)
Query: 684 KVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKE-ASPTPPSS-----PSVSGGL 737
K+ E S+ D D+ G L PP+ +P AK+ A PT PSS P S
Sbjct: 471 KLASAEDSAPADKDEDEPP----GHLQGEPPAQAPVAKKPARPTVPSSQRLPEPRASSSK 526
Query: 738 SSPSQGVGAELMGLQ---VDYWTAAQPADRKRDAEK 770
SPS V +L L+ + Y AA A R +D E+
Sbjct: 527 ESPSPSVREQLALLEARKLQYQRAALQAKRSQDLEQ 562
>gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]
Length = 1816
Score = 39.7 bits (91), Expect = 0.013
Identities = 75/330 (22%), Positives = 125/330 (37%), Gaps = 51/330 (15%)
Query: 175 SSQPIDHEDSTMQAGPK-------AKSTDNYSEEEYESFSSEQEASDDAVQGQDLDED-- 225
SSQ + ED T + +K + SE + S ++ SDD +G L+E+
Sbjct: 1250 SSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQ 1309
Query: 226 -----DFDVGKPKKQRRSIVRTTS-----------MTRQQ--NFKQKVVALLRRFKVSDE 267
D ++G+ S + +T QQ + ++ L + +
Sbjct: 1310 EEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEA 1369
Query: 268 VLDSE-QDPAEHIPEAEEDLDLLYDTLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYF--- 323
VL+ P+ P D L D+ +P S + +VL++ K P
Sbjct: 1370 VLEQHGSQPSNSYPSIISDSSALE---DLRNPEQS----TSEKAVLTSQKSSEYPISQNP 1422
Query: 324 EGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSLGGRQPSDSVSDTVALGVPGPREH 383
EGL S+ + E+ + S +KEP P K SL R S S ++ R +
Sbjct: 1423 EGL--SADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ-----NRNY 1475
Query: 384 PGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQA 443
P Q E +DV ++L SG TE+ +P EG G S + ++
Sbjct: 1476 PSQ-----EELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPES 1530
Query: 444 ARPQNERANSLDNERCPDARSQLQV-QLQI 472
++ S P + S L+V QL++
Sbjct: 1531 DPSEDRAPESARVGNIPSSTSALKVPQLKV 1560
>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
Length = 1863
Score = 39.7 bits (91), Expect = 0.013
Identities = 75/330 (22%), Positives = 125/330 (37%), Gaps = 51/330 (15%)
Query: 175 SSQPIDHEDSTMQAGPK-------AKSTDNYSEEEYESFSSEQEASDDAVQGQDLDED-- 225
SSQ + ED T + +K + SE + S ++ SDD +G L+E+
Sbjct: 1297 SSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQ 1356
Query: 226 -----DFDVGKPKKQRRSIVRTTS-----------MTRQQ--NFKQKVVALLRRFKVSDE 267
D ++G+ S + +T QQ + ++ L + +
Sbjct: 1357 EEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEA 1416
Query: 268 VLDSE-QDPAEHIPEAEEDLDLLYDTLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYF--- 323
VL+ P+ P D L D+ +P S + +VL++ K P
Sbjct: 1417 VLEQHGSQPSNSYPSIISDSSALE---DLRNPEQS----TSEKAVLTSQKSSEYPISQNP 1469
Query: 324 EGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSLGGRQPSDSVSDTVALGVPGPREH 383
EGL S+ + E+ + S +KEP P K SL R S S ++ R +
Sbjct: 1470 EGL--SADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQ-----NRNY 1522
Query: 384 PGQPEDSPEAEASTLDVFTERLPPSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQA 443
P Q E +DV ++L SG TE+ +P EG G S + ++
Sbjct: 1523 PSQ-----EELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPES 1577
Query: 444 ARPQNERANSLDNERCPDARSQLQV-QLQI 472
++ S P + S L+V QL++
Sbjct: 1578 DPSEDRAPESARVGNIPSSTSALKVPQLKV 1607
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 39.3 bits (90), Expect = 0.016
Identities = 43/195 (22%), Positives = 83/195 (42%), Gaps = 24/195 (12%)
Query: 263 KVSDEVLDSEQDPAEHIPEAEEDL-DLLYDTLDMEHPSDSGPDMEDDDSVLSTPKPKLRP 321
++ +E D E++ E E EE++ ++L D+ + G ED ST KL
Sbjct: 349 RIEEEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVG-VGQSEEDGTRPQSTSDQKLWE 407
Query: 322 YF----EGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRSLGGRQPSDSVSDTVALGV 377
+ + ++ E + + KEP A+ E+ ++ ++ + GV
Sbjct: 408 EVGEEAKKEAEEKAKEEAEEVAEEEAEKEPQDWAETKEEP---------EAEAEAASSGV 458
Query: 378 PGPREHPG-QPEDSPEAEASTLDVFTERLPPSGRI-----TKTESLVIPSTRSEGKQAGR 431
P ++HP Q ED+ +A + + E PPS + K+++L++PS+ S +
Sbjct: 459 PATKQHPEVQVEDT---DADSCPLMAEENPPSTVLPPPSPAKSDTLIVPSSASGTHRKKL 515
Query: 432 RGRSTSLKERQAARP 446
+E +A P
Sbjct: 516 PSEDDEAEELKALSP 530
>gi|239754138 PREDICTED: hypothetical protein [Homo sapiens]
Length = 274
Score = 39.3 bits (90), Expect = 0.016
Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 20/133 (15%)
Query: 338 IHSARSHKEPPSPADVPEKTRSLGGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEAST 397
IH ARS+ +PPS P R PS + L PR PG PE P +
Sbjct: 25 IHPARSN-QPPSRTCPPLPGPPSRSRSPSSRLK----LPADPPRALPGSPEPPPPPPPAA 79
Query: 398 LDVFTERLP--PSGRITKTESLVI--------PSTRSEGKQAGRRGRSTSLKERQAARPQ 447
V R+ P+ R++ + S V P +G++AG R RS + A P+
Sbjct: 80 PHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAA-----PASPR 134
Query: 448 NERANSLDNERCP 460
A ++ N+ P
Sbjct: 135 ARAARAISNQSSP 147
>gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo
sapiens]
Length = 274
Score = 39.3 bits (90), Expect = 0.016
Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 20/133 (15%)
Query: 338 IHSARSHKEPPSPADVPEKTRSLGGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEAST 397
IH ARS+ +PPS P R PS + L PR PG PE P +
Sbjct: 25 IHPARSN-QPPSRTCPPLPGPPSRSRSPSSRLK----LPADPPRALPGSPEPPPPPPPAA 79
Query: 398 LDVFTERLP--PSGRITKTESLVI--------PSTRSEGKQAGRRGRSTSLKERQAARPQ 447
V R+ P+ R++ + S V P +G++AG R RS + A P+
Sbjct: 80 PHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAA-----PASPR 134
Query: 448 NERANSLDNERCP 460
A ++ N+ P
Sbjct: 135 ARAARAISNQSSP 147
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 39.3 bits (90), Expect = 0.016
Identities = 47/163 (28%), Positives = 73/163 (44%), Gaps = 27/163 (16%)
Query: 336 GSIHSARS--HKEPPSP----ADVPEKTRSLGGRQPS-------DSVSDTVALGVPGPRE 382
GS+ + RS K+P SP + + E RS G PS DS ++TV +E
Sbjct: 25 GSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKE 84
Query: 383 HPGQPEDSPEAEASTLDVFTERLP-PSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKER 441
P S + + + TE S + TKT+ + P++ SEG+ G S S+ +
Sbjct: 85 EASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGE--GESSDSRSVNDE 142
Query: 442 QAARP----QNERANS------LDNERCPDARSQLQ-VQLQIP 473
++ P Q+ R+ S DNE D+ +Q Q +Q Q P
Sbjct: 143 GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPP 185
Score = 30.4 bits (67), Expect = 7.7
Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 690 PSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPPSSPS 732
PSSA G P + + ++ PP SP A +A P P +P+
Sbjct: 197 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA-PNQPQAPT 238
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 38.9 bits (89), Expect = 0.022
Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 24/198 (12%)
Query: 687 IVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPP---SSPSVSGGLSS---- 739
+VE ++A S + D APS S P +PA +AS P SSPSVS L++
Sbjct: 1106 LVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDP 1165
Query: 740 -------PSQGVG---AELMGLQVDYWTAAQPADRKR----DAEKKDLPVTKNTLKCTFR 785
P Q G + G + T Q + + + + + L + N +C
Sbjct: 1166 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCL-- 1223
Query: 786 SLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGISRLICT 845
L + + A+ +T + +++ KKV+ K++ K ES+ + + G T
Sbjct: 1224 -LGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAART 1282
Query: 846 ARQQQNMLRVLIDGVECS 863
R ++ +G E S
Sbjct: 1283 PRSKKKKKLGAGEGGEAS 1300
Score = 37.4 bits (85), Expect = 0.063
Identities = 53/246 (21%), Positives = 99/246 (40%), Gaps = 31/246 (12%)
Query: 241 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 300
+T+ + R++ ++ ++ +VSD + SE E EAE + L + S
Sbjct: 55 QTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEE--EAEAETAKATPRLASTNSSV 112
Query: 301 SGPDMEDDDSVLSTPKPKLRPYFE-------GLSHSSSQTEIGSIHSARSHKEPPSPADV 353
G D+ S+ K K + E + H ++ + ++ S +S P A+
Sbjct: 113 LGADLP------SSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKS---PRKSAEP 163
Query: 354 PEKTRSLGGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITK 413
T + + SV A PG GQ + S E +S+ D + S +I +
Sbjct: 164 SANTTLVSETEEEGSVPAFGAAAKPG-MVSAGQADSSSEDTSSSSDETDVEVKASEKILQ 222
Query: 414 TESLVIPSTRSEGKQA-----GRRGRSTSLKERQAARPQNERANSLD-----NERCPDAR 463
+ P+ + GK A G+ G S + +A +P+ + +S + E P A+
Sbjct: 223 VRAASAPAKGTPGKGATPAPPGKAGAVAS--QTKAGKPEEDSESSSEESSDSEEETPAAK 280
Query: 464 SQLQVQ 469
+ LQ +
Sbjct: 281 ALLQAK 286
Score = 36.6 bits (83), Expect = 0.11
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 16/130 (12%)
Query: 678 PFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPPSSPSVSGGL 737
P V VK E S ++ +SD + S T S +A+P +PS G +
Sbjct: 672 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT--SVKKTQAKANPAAARAPSAKGTI 729
Query: 738 SSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTLKCTFRSLQVSRLPSSGE 797
S+P + V TAA A K+ + K P +N T + + +PS G+
Sbjct: 730 SAPGKVV------------TAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK 775
Query: 798 AAATPTMSMT 807
A AT + T
Sbjct: 776 AVATAAQAQT 785
Score = 33.1 bits (74), Expect = 1.2
Identities = 45/190 (23%), Positives = 67/190 (35%), Gaps = 26/190 (13%)
Query: 667 SPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAK----E 722
SP + QK P VK +S +S +S D+A S + T A PA K +
Sbjct: 506 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 565
Query: 723 ASPTPPS---------------SPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRD 767
A P + +P +G +SP+ A G Q ++ + +
Sbjct: 566 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSE 625
Query: 768 AEKKDLPVTKNTLKCTFRSLQVSRLP-------SSGEAAATPTMSMTVVTKEKNKKVMFL 820
EK L VT K + LQV G A P + VT+ K +K
Sbjct: 626 EEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDS 685
Query: 821 PKKAKDKDVE 830
++ D E
Sbjct: 686 ESSEEESDSE 695
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 38.9 bits (89), Expect = 0.022
Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 24/198 (12%)
Query: 687 IVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPP---SSPSVSGGLSS---- 739
+VE ++A S + D APS S P +PA +AS P SSPSVS L++
Sbjct: 1145 LVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDP 1204
Query: 740 -------PSQGVG---AELMGLQVDYWTAAQPADRKR----DAEKKDLPVTKNTLKCTFR 785
P Q G + G + T Q + + + + + L + N +C
Sbjct: 1205 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCL-- 1262
Query: 786 SLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGISRLICT 845
L + + A+ +T + +++ KKV+ K++ K ES+ + + G T
Sbjct: 1263 -LGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAART 1321
Query: 846 ARQQQNMLRVLIDGVECS 863
R ++ +G E S
Sbjct: 1322 PRSKKKKKLGAGEGGEAS 1339
Score = 36.6 bits (83), Expect = 0.11
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 16/130 (12%)
Query: 678 PFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPPSSPSVSGGL 737
P V VK E S ++ +SD + S T S +A+P +PS G +
Sbjct: 749 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT--SVKKTQAKANPAAARAPSAKGTI 806
Query: 738 SSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTLKCTFRSLQVSRLPSSGE 797
S+P + V TAA A K+ + K P +N T + + +PS G+
Sbjct: 807 SAPGKVV------------TAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK 852
Query: 798 AAATPTMSMT 807
A AT + T
Sbjct: 853 AVATAAQAQT 862
Score = 33.1 bits (74), Expect = 1.2
Identities = 45/190 (23%), Positives = 67/190 (35%), Gaps = 26/190 (13%)
Query: 667 SPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAK----E 722
SP + QK P VK +S +S +S D+A S + T A PA K +
Sbjct: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
Query: 723 ASPTPPS---------------SPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRD 767
A P + +P +G +SP+ A G Q ++ + +
Sbjct: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSE 702
Query: 768 AEKKDLPVTKNTLKCTFRSLQVSRLP-------SSGEAAATPTMSMTVVTKEKNKKVMFL 820
EK L VT K + LQV G A P + VT+ K +K
Sbjct: 703 EEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDS 762
Query: 821 PKKAKDKDVE 830
++ D E
Sbjct: 763 ESSEEESDSE 772
Score = 32.3 bits (72), Expect = 2.0
Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 36/173 (20%)
Query: 681 GVVKVGIVEPSSA-TSGDSDDAAPSGSGTL-------SSTPPSASPAAKEASPTPPS--- 729
G+V G + SS TS SD+ G ++ SS SPA K A+P P
Sbjct: 189 GMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARK-AAPAPGKVGD 247
Query: 730 -SPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE-----KKDLPV-TKNTLKC 782
+P V GG P++ A +P + +E +++ P T++ +K
Sbjct: 248 VTPQVKGGALPPAK--------------RAKKPEEESESSEEGSESEEEAPAGTRSQVKA 293
Query: 783 TFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAK-DKDVESKSQ 834
+ + LQV +S A TP T K V K K ++D ES S+
Sbjct: 294 SEKILQVR--AASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE 344
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 38.9 bits (89), Expect = 0.022
Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 24/198 (12%)
Query: 687 IVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPP---SSPSVSGGLSS---- 739
+VE ++A S + D APS S P +PA +AS P SSPSVS L++
Sbjct: 1182 LVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDP 1241
Query: 740 -------PSQGVG---AELMGLQVDYWTAAQPADRKR----DAEKKDLPVTKNTLKCTFR 785
P Q G + G + T Q + + + + + L + N +C
Sbjct: 1242 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCL-- 1299
Query: 786 SLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGISRLICT 845
L + + A+ +T + +++ KKV+ K++ K ES+ + + G T
Sbjct: 1300 -LGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAART 1358
Query: 846 ARQQQNMLRVLIDGVECS 863
R ++ +G E S
Sbjct: 1359 PRSKKKKKLGAGEGGEAS 1376
Score = 36.6 bits (83), Expect = 0.11
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 16/130 (12%)
Query: 678 PFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPPSSPSVSGGL 737
P V VK E S ++ +SD + S T S +A+P +PS G +
Sbjct: 749 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT--SVKKTQAKANPAAARAPSAKGTI 806
Query: 738 SSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTLKCTFRSLQVSRLPSSGE 797
S+P + V TAA A K+ + K P +N T + + +PS G+
Sbjct: 807 SAPGKVV------------TAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK 852
Query: 798 AAATPTMSMT 807
A AT + T
Sbjct: 853 AVATAAQAQT 862
Score = 33.1 bits (74), Expect = 1.2
Identities = 45/190 (23%), Positives = 67/190 (35%), Gaps = 26/190 (13%)
Query: 667 SPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAK----E 722
SP + QK P VK +S +S +S D+A S + T A PA K +
Sbjct: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
Query: 723 ASPTPPS---------------SPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRD 767
A P + +P +G +SP+ A G Q ++ + +
Sbjct: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSE 702
Query: 768 AEKKDLPVTKNTLKCTFRSLQVSRLP-------SSGEAAATPTMSMTVVTKEKNKKVMFL 820
EK L VT K + LQV G A P + VT+ K +K
Sbjct: 703 EEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDS 762
Query: 821 PKKAKDKDVE 830
++ D E
Sbjct: 763 ESSEEESDSE 772
Score = 32.3 bits (72), Expect = 2.0
Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 36/173 (20%)
Query: 681 GVVKVGIVEPSSA-TSGDSDDAAPSGSGTL-------SSTPPSASPAAKEASPTPPS--- 729
G+V G + SS TS SD+ G ++ SS SPA K A+P P
Sbjct: 189 GMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARK-AAPAPGKVGD 247
Query: 730 -SPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE-----KKDLPV-TKNTLKC 782
+P V GG P++ A +P + +E +++ P T++ +K
Sbjct: 248 VTPQVKGGALPPAK--------------RAKKPEEESESSEEGSESEEEAPAGTRSQVKA 293
Query: 783 TFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAK-DKDVESKSQ 834
+ + LQV +S A TP T K V K K ++D ES S+
Sbjct: 294 SEKILQVR--AASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE 344
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 38.9 bits (89), Expect = 0.022
Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 24/198 (12%)
Query: 687 IVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPP---SSPSVSGGLSS---- 739
+VE ++A S + D APS S P +PA +AS P SSPSVS L++
Sbjct: 1105 LVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDP 1164
Query: 740 -------PSQGVG---AELMGLQVDYWTAAQPADRKR----DAEKKDLPVTKNTLKCTFR 785
P Q G + G + T Q + + + + + L + N +C
Sbjct: 1165 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCL-- 1222
Query: 786 SLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGISRLICT 845
L + + A+ +T + +++ KKV+ K++ K ES+ + + G T
Sbjct: 1223 -LGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAART 1281
Query: 846 ARQQQNMLRVLIDGVECS 863
R ++ +G E S
Sbjct: 1282 PRSKKKKKLGAGEGGEAS 1299
Score = 37.4 bits (85), Expect = 0.063
Identities = 53/246 (21%), Positives = 99/246 (40%), Gaps = 31/246 (12%)
Query: 241 RTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPAEHIPEAEEDLDLLYDTLDMEHPSD 300
+T+ + R++ ++ ++ +VSD + SE E EAE + L + S
Sbjct: 55 QTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEE--EAEAETAKATPRLASTNSSV 112
Query: 301 SGPDMEDDDSVLSTPKPKLRPYFE-------GLSHSSSQTEIGSIHSARSHKEPPSPADV 353
G D+ S+ K K + E + H ++ + ++ S +S P A+
Sbjct: 113 LGADLP------SSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKS---PRKSAEP 163
Query: 354 PEKTRSLGGRQPSDSVSDTVALGVPGPREHPGQPEDSPEAEASTLDVFTERLPPSGRITK 413
T + + SV A PG GQ + S E +S+ D + S +I +
Sbjct: 164 SANTTLVSETEEEGSVPAFGAAAKPG-MVSAGQADSSSEDTSSSSDETDVEVKASEKILQ 222
Query: 414 TESLVIPSTRSEGKQA-----GRRGRSTSLKERQAARPQNERANSLD-----NERCPDAR 463
+ P+ + GK A G+ G S + +A +P+ + +S + E P A+
Sbjct: 223 VRAASAPAKGTPGKGATPAPPGKAGAVAS--QTKAGKPEEDSESSSEESSDSEEETPAAK 280
Query: 464 SQLQVQ 469
+ LQ +
Sbjct: 281 ALLQAK 286
Score = 36.6 bits (83), Expect = 0.11
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 16/130 (12%)
Query: 678 PFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPPSSPSVSGGL 737
P V VK E S ++ +SD + S T S +A+P +PS G +
Sbjct: 672 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT--SVKKTQAKANPAAARAPSAKGTI 729
Query: 738 SSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTLKCTFRSLQVSRLPSSGE 797
S+P + V TAA A K+ + K P +N T + + +PS G+
Sbjct: 730 SAPGKVV------------TAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK 775
Query: 798 AAATPTMSMT 807
A AT + T
Sbjct: 776 AVATAAQAQT 785
Score = 33.1 bits (74), Expect = 1.2
Identities = 45/190 (23%), Positives = 67/190 (35%), Gaps = 26/190 (13%)
Query: 667 SPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAK----E 722
SP + QK P VK +S +S +S D+A S + T A PA K +
Sbjct: 506 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 565
Query: 723 ASPTPPS---------------SPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRD 767
A P + +P +G +SP+ A G Q ++ + +
Sbjct: 566 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSE 625
Query: 768 AEKKDLPVTKNTLKCTFRSLQVSRLP-------SSGEAAATPTMSMTVVTKEKNKKVMFL 820
EK L VT K + LQV G A P + VT+ K +K
Sbjct: 626 EEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDS 685
Query: 821 PKKAKDKDVE 830
++ D E
Sbjct: 686 ESSEEESDSE 695
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 38.9 bits (89), Expect = 0.022
Identities = 47/198 (23%), Positives = 81/198 (40%), Gaps = 24/198 (12%)
Query: 687 IVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPP---SSPSVSGGLSS---- 739
+VE ++A S + D APS S P +PA +AS P SSPSVS L++
Sbjct: 1144 LVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDP 1203
Query: 740 -------PSQGVG---AELMGLQVDYWTAAQPADRKR----DAEKKDLPVTKNTLKCTFR 785
P Q G + G + T Q + + + + + L + N +C
Sbjct: 1204 DGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCL-- 1261
Query: 786 SLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGISRLICT 845
L + + A+ +T + +++ KKV+ K++ K ES+ + + G T
Sbjct: 1262 -LGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAART 1320
Query: 846 ARQQQNMLRVLIDGVECS 863
R ++ +G E S
Sbjct: 1321 PRSKKKKKLGAGEGGEAS 1338
Score = 36.6 bits (83), Expect = 0.11
Identities = 35/130 (26%), Positives = 53/130 (40%), Gaps = 16/130 (12%)
Query: 678 PFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPPSSPSVSGGL 737
P V VK E S ++ +SD + S T S +A+P +PS G +
Sbjct: 749 PTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKT--SVKKTQAKANPAAARAPSAKGTI 806
Query: 738 SSPSQGVGAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTLKCTFRSLQVSRLPSSGE 797
S+P + V TAA A K+ + K P +N T + + +PS G+
Sbjct: 807 SAPGKVV------------TAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK 852
Query: 798 AAATPTMSMT 807
A AT + T
Sbjct: 853 AVATAAQAQT 862
Score = 33.1 bits (74), Expect = 1.2
Identities = 45/190 (23%), Positives = 67/190 (35%), Gaps = 26/190 (13%)
Query: 667 SPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAK----E 722
SP + QK P VK +S +S +S D+A S + T A PA K +
Sbjct: 583 SPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK 642
Query: 723 ASPTPPS---------------SPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRD 767
A P + +P +G +SP+ A G Q ++ + +
Sbjct: 643 ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSE 702
Query: 768 AEKKDLPVTKNTLKCTFRSLQVSRLP-------SSGEAAATPTMSMTVVTKEKNKKVMFL 820
EK L VT K + LQV G A P + VT+ K +K
Sbjct: 703 EEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDS 762
Query: 821 PKKAKDKDVE 830
++ D E
Sbjct: 763 ESSEEESDSE 772
Score = 32.3 bits (72), Expect = 2.0
Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 36/173 (20%)
Query: 681 GVVKVGIVEPSSA-TSGDSDDAAPSGSGTL-------SSTPPSASPAAKEASPTPPS--- 729
G+V G + SS TS SD+ G ++ SS SPA K A+P P
Sbjct: 189 GMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARK-AAPAPGKVGD 247
Query: 730 -SPSVSGGLSSPSQGVGAELMGLQVDYWTAAQPADRKRDAE-----KKDLPV-TKNTLKC 782
+P V GG P++ A +P + +E +++ P T++ +K
Sbjct: 248 VTPQVKGGALPPAK--------------RAKKPEEESESSEEGSESEEEAPAGTRSQVKA 293
Query: 783 TFRSLQVSRLPSSGEAAATPTMSMTVVTKEKNKKVMFLPKKAK-DKDVESKSQ 834
+ + LQV +S A TP T K V K K ++D ES S+
Sbjct: 294 SEKILQVR--AASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE 344
>gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo
sapiens]
Length = 874
Score = 38.5 bits (88), Expect = 0.028
Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 687 IVEPSSATSGDSDDAAPSGS-GTLSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGVG 745
+ EP S + S D+ P GS +LSS + K AS P +++PS G
Sbjct: 614 LAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSASCQPREKSGGIPWIATPSSSNG 673
Query: 746 AELMGLQVDYWTAAQPADRKRDAEKKD 772
+ +GL WT + + + DA K D
Sbjct: 674 QKSLGL----WTTSPESSSREDATKTD 696
>gi|22547121 tumor necrosis factor receptor superfamily, member 10c
precursor [Homo sapiens]
Length = 259
Score = 38.1 bits (87), Expect = 0.037
Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 3/98 (3%)
Query: 647 GANCAHQLPIAEAMLTYKQKSPDEESSQKFIPFVGVVKVGIVEPSSATSGDSDDAAPSGS 706
GAN + P AE + +P + + G E + + G AP+
Sbjct: 154 GANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTP---APAAE 210
Query: 707 GTLSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGV 744
T++++P + +PAA+E T P +P+ S LS G+
Sbjct: 211 ETMTTSPGTPAPAAEETMTTSPGTPASSHYLSCTIVGI 248
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
sapiens]
Length = 1085
Score = 37.7 bits (86), Expect = 0.048
Identities = 58/257 (22%), Positives = 90/257 (35%), Gaps = 34/257 (13%)
Query: 191 KAKSTDNYSEEEYESFSSEQEASDDAVQGQDLDEDDFDVGKPKKQRRSIVRTTSMTRQQN 250
K + D+Y + Y + +E DA ED+ + P + R+ +
Sbjct: 707 KCMAGDDYCDSPYSEHGTLEEVDQDAGTEPHTSEDECE---PIEAIAKFDYVGRSARELS 763
Query: 251 FKQKVVALLRRFKVSDEVLDSEQD------PAEHIPEAEEDLDLLYDTLDMEHPSD--SG 302
FK K +LL + S++ + + P ++I + D D DTL + S+ SG
Sbjct: 764 FK-KGASLLLYHRASEDWWEGRHNGIDGLVPHQYIVVQDMD-DTFSDTLSQKADSEASSG 821
Query: 303 PDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTEIGSIHSARSHKEPPSPADVPEKTRS--L 360
P ED S P + + G + R EPP P P +T
Sbjct: 822 PVTEDKSSSKDMNSP------------TDRHPDGYLARQRKRGEPPPPVRRPGRTSDGHC 869
Query: 361 GGRQPSDSVSDTVALGVPGPREHP-------GQPEDSPEAEASTLDVFTERLPPSGRITK 413
P + +V LG P HP G DSPE + + K
Sbjct: 870 PLHPPHALSNSSVDLGSPSLASHPRGLLQNRGLNNDSPERRRRPGHGSLTNISRHDSLKK 929
Query: 414 TESLVIPSTRSEGKQAG 430
+S I + S G+ G
Sbjct: 930 IDSPPIRRSTSSGQYTG 946
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,980,107
Number of Sequences: 37866
Number of extensions: 1886753
Number of successful extensions: 13998
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 365
Number of HSP's that attempted gapping in prelim test: 12399
Number of HSP's gapped (non-prelim): 1891
length of query: 893
length of database: 18,247,518
effective HSP length: 111
effective length of query: 782
effective length of database: 14,044,392
effective search space: 10982714544
effective search space used: 10982714544
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.