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Search of human proteins with 15451914
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15451914 BAI1-associated protein 3 [Homo sapiens]
(1187 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15451914 BAI1-associated protein 3 [Homo sapiens] 2377 0.0
gi|46195765 unc-13 homolog D [Homo sapiens] 571 e-162
gi|110611226 UNC13 (C. elegans)-like [Homo sapiens] 109 1e-23
gi|122937514 unc-13 homolog C [Homo sapiens] 109 2e-23
gi|122937247 unc-13 homolog A [Homo sapiens] 93 2e-18
gi|92859638 synaptotagmin V [Homo sapiens] 69 2e-11
gi|40068038 B/K protein [Homo sapiens] 68 5e-11
gi|6005997 double C2-like domains, beta [Homo sapiens] 68 6e-11
gi|238550198 synaptotagmin III [Homo sapiens] 67 1e-10
gi|238550196 synaptotagmin III [Homo sapiens] 67 1e-10
gi|14150054 synaptotagmin III [Homo sapiens] 67 1e-10
gi|209447073 synaptotagmin I [Homo sapiens] 65 3e-10
gi|5032139 synaptotagmin I [Homo sapiens] 65 3e-10
gi|209447070 synaptotagmin I [Homo sapiens] 65 3e-10
gi|4506067 protein kinase C, alpha [Homo sapiens] 62 2e-09
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 62 4e-09
gi|38570146 synaptotagmin VII [Homo sapiens] 62 4e-09
gi|211059429 synaptotagmin II [Homo sapiens] 61 6e-09
gi|31543670 synaptotagmin II [Homo sapiens] 61 6e-09
gi|47078261 double C2-like domains, alpha [Homo sapiens] 61 6e-09
gi|13384594 protein kinase C, gamma [Homo sapiens] 61 7e-09
gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens] 60 1e-08
gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens] 60 1e-08
gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens] 59 2e-08
gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens] 59 2e-08
gi|24308219 synaptotagmin IV [Homo sapiens] 59 3e-08
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 59 4e-08
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 59 4e-08
gi|45504376 synaptotagmin VI [Homo sapiens] 58 6e-08
gi|28376627 synaptotagmin IX [Homo sapiens] 57 8e-08
>gi|15451914 BAI1-associated protein 3 [Homo sapiens]
Length = 1187
Score = 2377 bits (6159), Expect = 0.0
Identities = 1187/1187 (100%), Positives = 1187/1187 (100%)
Query: 1 MRPRGAAFAAGPPGDLHLGTAIGFAGAIWRSRSPAMSTLLDIKSSVLRQVQVCPSFRRRT 60
MRPRGAAFAAGPPGDLHLGTAIGFAGAIWRSRSPAMSTLLDIKSSVLRQVQVCPSFRRRT
Sbjct: 1 MRPRGAAFAAGPPGDLHLGTAIGFAGAIWRSRSPAMSTLLDIKSSVLRQVQVCPSFRRRT 60
Query: 61 EQDPGSASADPQEPATGAWKPGDGVEFFAHMRLMLKKGEGRQGLPCLEVPLRSGSPAPPE 120
EQDPGSASADPQEPATGAWKPGDGVEFFAHMRLMLKKGEGRQGLPCLEVPLRSGSPAPPE
Sbjct: 61 EQDPGSASADPQEPATGAWKPGDGVEFFAHMRLMLKKGEGRQGLPCLEVPLRSGSPAPPE 120
Query: 121 PVDPSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPDQVDDEEALLSYLQQVFGTSLEEH 180
PVDPSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPDQVDDEEALLSYLQQVFGTSLEEH
Sbjct: 121 PVDPSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPDQVDDEEALLSYLQQVFGTSLEEH 180
Query: 181 TEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQ 240
TEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQ
Sbjct: 181 TEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQ 240
Query: 241 RFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHDDDV 300
RFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHDDDV
Sbjct: 241 RFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHDDDV 300
Query: 301 SLVEACRKLNEVIGLKGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVREVPVAG 360
SLVEACRKLNEVIGLKGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVREVPVAG
Sbjct: 301 SLVEACRKLNEVIGLKGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVREVPVAG 360
Query: 361 VDRWFKLEPRSSASRVQGHCHLVLKLITTQRDTAMSQRGRSGFLSHLLLLSHLLRLEHSA 420
VDRWFKLEPRSSASRVQGHCHLVLKLITTQRDTAMSQRGRSGFLSHLLLLSHLLRLEHSA
Sbjct: 361 VDRWFKLEPRSSASRVQGHCHLVLKLITTQRDTAMSQRGRSGFLSHLLLLSHLLRLEHSA 420
Query: 421 EEPNSSSWRGELSTPAATILCLHGAQSNLSPLQLAVLHWQVSSRHHQTCTLDYSYLLGLL 480
EEPNSSSWRGELSTPAATILCLHGAQSNLSPLQLAVLHWQVSSRHHQTCTLDYSYLLGLL
Sbjct: 421 EEPNSSSWRGELSTPAATILCLHGAQSNLSPLQLAVLHWQVSSRHHQTCTLDYSYLLGLL 480
Query: 481 EDMQAHWEEAPSLPQEQEESLADSLSAFSEFGLQLLRQLRDYFPATNSTAVHRLELLLKC 540
EDMQAHWEEAPSLPQEQEESLADSLSAFSEFGLQLLRQLRDYFPATNSTAVHRLELLLKC
Sbjct: 481 EDMQAHWEEAPSLPQEQEESLADSLSAFSEFGLQLLRQLRDYFPATNSTAVHRLELLLKC 540
Query: 541 LGKLQLFQPSFEICPFESELNMDIAAALKRGNREWYDRILNDKSPREQPGPQRLPGLVVL 600
LGKLQLFQPSFEICPFESELNMDIAAALKRGNREWYDRILNDKSPREQPGPQRLPGLVVL
Sbjct: 541 LGKLQLFQPSFEICPFESELNMDIAAALKRGNREWYDRILNDKSPREQPGPQRLPGLVVL 600
Query: 601 ADAVYDDLQFCYSVYASLFHSILNVDVFTLTFRQLERLVAEEAWVLTEELSPKMTLEVAS 660
ADAVYDDLQFCYSVYASLFHSILNVDVFTLTFRQLERLVAEEAWVLTEELSPKMTLEVAS
Sbjct: 601 ADAVYDDLQFCYSVYASLFHSILNVDVFTLTFRQLERLVAEEAWVLTEELSPKMTLEVAS 660
Query: 661 GLFELYLTLADLQRFWDSIPGRDSRSLALAGIHAPFLPAVKLWFQVLRDQAKWRLQGAVD 720
GLFELYLTLADLQRFWDSIPGRDSRSLALAGIHAPFLPAVKLWFQVLRDQAKWRLQGAVD
Sbjct: 661 GLFELYLTLADLQRFWDSIPGRDSRSLALAGIHAPFLPAVKLWFQVLRDQAKWRLQGAVD 720
Query: 721 MDTLEPVDASSRHSSSAATAGLCLSHIQELWVRLAWPDPAQAQGLGTQLGQDVCEATLFY 780
MDTLEPVDASSRHSSSAATAGLCLSHIQELWVRLAWPDPAQAQGLGTQLGQDVCEATLFY
Sbjct: 721 MDTLEPVDASSRHSSSAATAGLCLSHIQELWVRLAWPDPAQAQGLGTQLGQDVCEATLFY 780
Query: 781 TELLRKKVDTQPGAAGEAVSEALCVVLNNVELVRKAAGQALKGLAWPEGATGPEGVLPRP 840
TELLRKKVDTQPGAAGEAVSEALCVVLNNVELVRKAAGQALKGLAWPEGATGPEGVLPRP
Sbjct: 781 TELLRKKVDTQPGAAGEAVSEALCVVLNNVELVRKAAGQALKGLAWPEGATGPEGVLPRP 840
Query: 841 LLSCTQALDDDLQREAHTVTAHLTSKMVGDIRKYVQHISLSPDSIQNDEAVAPLMKYLDE 900
LLSCTQALDDDLQREAHTVTAHLTSKMVGDIRKYVQHISLSPDSIQNDEAVAPLMKYLDE
Sbjct: 841 LLSCTQALDDDLQREAHTVTAHLTSKMVGDIRKYVQHISLSPDSIQNDEAVAPLMKYLDE 900
Query: 901 KLALLNASLVKGNLSRVLEALWELLLQAILQALGANRDVSADFYSRFHFTLEALVSFFHA 960
KLALLNASLVKGNLSRVLEALWELLLQAILQALGANRDVSADFYSRFHFTLEALVSFFHA
Sbjct: 901 KLALLNASLVKGNLSRVLEALWELLLQAILQALGANRDVSADFYSRFHFTLEALVSFFHA 960
Query: 961 EGQGLPLESLRDGSYKRLKEELRLHKCSTRECIEQFYLDKLKQRTLEQNRFGRLSVRCHY 1020
EGQGLPLESLRDGSYKRLKEELRLHKCSTRECIEQFYLDKLKQRTLEQNRFGRLSVRCHY
Sbjct: 961 EGQGLPLESLRDGSYKRLKEELRLHKCSTRECIEQFYLDKLKQRTLEQNRFGRLSVRCHY 1020
Query: 1021 EAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTRTLHPVYD 1080
EAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTRTLHPVYD
Sbjct: 1021 EAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTRTLHPVYD 1080
Query: 1081 ELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVTGVARPQVGGGARAG 1140
ELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVTGVARPQVGGGARAG
Sbjct: 1081 ELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVTGVARPQVGGGARAG 1140
Query: 1141 QPVTLHLCRPRAQVRSALRRLEGRTSKEAQEFVKKLKELEKCMEADP 1187
QPVTLHLCRPRAQVRSALRRLEGRTSKEAQEFVKKLKELEKCMEADP
Sbjct: 1141 QPVTLHLCRPRAQVRSALRRLEGRTSKEAQEFVKKLKELEKCMEADP 1187
>gi|46195765 unc-13 homolog D [Homo sapiens]
Length = 1090
Score = 571 bits (1472), Expect = e-162
Identities = 370/1068 (34%), Positives = 565/1068 (52%), Gaps = 45/1068 (4%)
Query: 119 PEPVDPSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPDQVDDEEALLSYLQQVFGTSLE 178
PE PS +PE+ +LYE+ALYTVL+R G P+ V + LL YLQ+ F E
Sbjct: 38 PEIQPPS---HHFSPEQRALLYEDALYTVLHRLGHPEPNHVTEASELLRYLQEAFHVEPE 94
Query: 179 EHTEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATR-EPRAQ 237
EH + ++RVR+ + P + LK +V +AK +L KD +GFSDPYC+LGI P ++
Sbjct: 95 EHQQTLQRVRELEKPIFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSR 154
Query: 238 KEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHD 297
Q+ R +P + T+V + TLNPVW E F+ E ED++ HLD+WD D
Sbjct: 155 HRQKAVVRH------TIPEEETHRTQVITQTLNPVWDETFILEFEDITNASFHLDMWDLD 208
Query: 298 DDVSLVEACR-KLNEVIGLKGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVREV 356
VE+ R KL E+ L G+ R FK+ K + DDFLG + + ++++
Sbjct: 209 T----VESVRQKLGELTDLHGLRRIFKEARK-----------DKGQDDFLGNVVLRLQDL 253
Query: 357 PVAGVDRWFKLEPRSSASRVQGHCHLVLKLITTQRDTAMSQRGRSGFLSHLLLLSHLLRL 416
D+W+ LEPR+ +G CHL +LI +R T+ S R + + HL LL L+
Sbjct: 254 RCRE-DQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSAS-RSQPSYTVHLHLLQQLVSH 311
Query: 417 EHSAEEPNSSSWRGELSTPAATILCLHGAQSNLSPLQLAVLHWQVSSRHHQTCTLDYSYL 476
E + E S+SW G LS AAT+L LH Q +LS ++ W SR +Q+ S L
Sbjct: 312 EVTQHEAGSTSWDGSLSPQAATVLFLHATQKDLSDFHQSMAQWLAYSRLYQSLEFPSSCL 371
Query: 477 LGLLEDMQAHWEEAPSLPQEQEESLADSLSAFSEFGLQLLRQLRDYFPATNSTAVHRLEL 536
L + ++ W + L EQ+E LA S S+ +GL L+R+ R FP + S + RL+
Sbjct: 372 LHPITSIEYQWIQG-RLKAEQQEELAASFSSLLTYGLSLIRRFRSVFPLSVSDSPARLQS 430
Query: 537 LLKCLGKLQLFQPSFEICPFESELNMDIAAALKRGNREWYDRILNDKSPREQPGPQRLPG 596
LL+ L ++ + E+CP + L + AL+ G EW+ P Q P+
Sbjct: 431 LLRVLVQMCKMKAFGELCPNTAPLPQLVTEALQTGTTEWFHLKQQHHQPMVQGIPEAGKA 490
Query: 597 LVVLADAVYDDLQFCYSVYASLFHSILNVDVFTLTFRQLERLVAEEAWVLTEELSPKMTL 656
L+ L V DL C + +FH+ L + +F++ FR+L+ LVA+ T + ++
Sbjct: 491 LLGLVQDVIGDLHQCQRTWDKIFHNTLKIHLFSMAFRELQWLVAKRVQDHTTVVGDVVSP 550
Query: 657 EVASGLFELYLTLADLQRFWDSIPGRDSRSLALAGIHAPFLPAVKLWFQVLRDQAKWRLQ 716
E+ LF+LY++L +L + S RD LAL H F PA+ W Q ++A R+Q
Sbjct: 551 EMGESLFQLYISLKELCQLRMSSSERDG-VLALDNFHRWFQPAIPSWLQKTYNEALARVQ 609
Query: 717 GAVDMDTLEPVDASSRHSSSAATAGLCLSHIQELWVRLAWPDPAQAQGLGTQLGQDVCEA 776
AV MD L P+ ++HS+SA C + I +L WPDP +A + + +D C
Sbjct: 610 RAVQMDELVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRL 669
Query: 777 TLFYTELLR---KKVDTQPGAAGEAVSEALCVVLNNVELVRKAAGQALKGLAWPE----- 828
L Y L++ +++ + G+A + LCVV+N++E +R G+ LAW
Sbjct: 670 ALVYCSLIKARARELSSGQKDQGQAAN-MLCVVVNDMEQLRLVIGKLPAQLAWEALEQRV 728
Query: 829 GATGPEGVLPRPLLSCTQALDDDLQREAHTVTAHLTSKMVGDIRKYVQHISLSPDSIQND 888
GA +G L L + Q+ L E T L ++ I K++Q + +S+ +
Sbjct: 729 GAVLEQGQLQNTLHAQLQSALAGLGHEIRTGVRTLAEQLEVGIAKHIQKLVGVRESVLPE 788
Query: 889 EAVAPLMKYLDEKLALLNASLVKGNLSRVLEALWELLLQAILQALGANRDVSADFYSRFH 948
+A+ PLMK+L+ +L +N +LV+ N S +L LW L +++A + R S +R
Sbjct: 789 DAILPLMKFLEVELCYMNTNLVQENFSSLLTLLWTHTLTVLVEAAASQRSSSLAS-NRLK 847
Query: 949 FTLEALVSFFHAEGQGLPLESLRDGSYKRLKEELRLHKCSTRECIEQFYLDKLKQRT-LE 1007
L+ L FHAEG GLP ++L +++ L+ +L L S+RE I +++ +++Q+
Sbjct: 848 IALQNLEICFHAEGCGLPPKALHTATFQALQRDLELQAASSRELIRKYFCSRIQQQAETT 907
Query: 1008 QNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQR 1067
G ++V+ Y A+EQ+L VE+L A+ LLPLD+NG SDPFV + L P H FP + ++
Sbjct: 908 SEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARE 967
Query: 1068 TQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVTG 1127
TQ + LHP++DE F F VPAE CR+ AC+L TV+D+D L +D GEA L L V G
Sbjct: 968 TQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREVPG 1027
Query: 1128 VARPQVGGGARAGQPVTLHLCRPRAQVRSALRRLEGRT-SKEAQEFVK 1174
++ + G L L P L+ LEGR +EAQ FV+
Sbjct: 1028 LSGSEEPGEV---PQTRLPLTYPAPNGDPILQLLEGRKGDREAQVFVR 1072
>gi|110611226 UNC13 (C. elegans)-like [Homo sapiens]
Length = 1591
Score = 109 bits (273), Expect = 1e-23
Identities = 213/1019 (20%), Positives = 379/1019 (37%), Gaps = 184/1019 (18%)
Query: 165 LLSYLQQVFGTSLEEHTEAIERVRKAKAP-----TYALKVSVMRAKNLLAKDPNGFSDPY 219
+ ++ VF + H + ++ V+++ + + ++V+ A+ L AKD G SDPY
Sbjct: 565 IFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPY 624
Query: 220 CMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLF 279
+ + K KR T+ LNPVW+E F F
Sbjct: 625 VTVQV--------------------SKTKKR-----------TKTIFGNLNPVWEEKFHF 653
Query: 280 EIEDVSTDQLHLDIWDHDDDVSLVEACRKLNEVIGLKGMGRYFKQIVKSARANGTAGPTE 339
E + S+D++ + +WD DDD+ KQ +K
Sbjct: 654 ECHN-SSDRIKVRVWDEDDDIK------------------SRVKQRLKR----------- 683
Query: 340 DHTDDFLGCLNIPVREVPVAGVDRWFKLEPRSSASRVQGHCHLVLKLITTQRDTAMSQRG 399
+DDFLG I VR + +D W+ LE R+ S V G L + + +
Sbjct: 684 -ESDDFLGQTIIEVRTLS-GEMDVWYNLEKRTDKSAVSGAIRLQISVEIKGEEKVAPYHV 741
Query: 400 RSGFLSHLLLLSHLLRLEHSA-----EEPNSSSWRGELSTPAATILCLHGAQSNLSPLQL 454
+ L H L +L ++ S E +W+ A I+ + + +
Sbjct: 742 QYTCL-HENLFHYLTDIQGSGGVRIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQ 800
Query: 455 AVLHWQVSSRHHQTCTLDYSYLLGLLEDMQAHWEEAPSLPQEQEESLADSLSAFSEFG-- 512
A+ H+ S + C + + LL ++ A++ + S +D +A S FG
Sbjct: 801 AMTHFACLSSKYM-CPGVPAVMSTLLANINAYYAHTTA---STNVSASDRFAA-SNFGKE 855
Query: 513 --LQLLRQL-----------RDYFPATNSTAVHRLELLLKCLGKLQLFQ---PSFEICPF 556
++LL QL R+ FPA + + L+ + L + F+ + P
Sbjct: 856 RFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSPPR 915
Query: 557 ESELNMDIAAALKRGNREW--------YDRI--LNDKSPREQPGPQRL-----PGLVVLA 601
S++ D A E+ Y R L + P E+ GP P L+ L
Sbjct: 916 ASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLITLI 975
Query: 602 DAVYDDLQFCYSVYASLFHSILNVDVFTLTFRQLERLVAEEAWVLTEELSPKMTLEVASG 661
++ ++ + Y+ + F LNV ++ + L A++ EE K L ++
Sbjct: 976 VSIIEEDKNSYTPVLNQFPQELNVG--KVSAEVMWHLFAQDMKYALEE-HEKDHLCKSAD 1032
Query: 662 LFELYLTLADLQRFWDSIPGRDSRSLALAGIHAPFLPA-----VKLWFQVLRDQAKWRLQ 716
L+ + L + R L + P PA V W D + L+
Sbjct: 1033 YMNLHFKVKWLHNEY-------VRDLPVLQGQVPEYPAWFEQFVLQWLDENEDVSLEFLR 1085
Query: 717 GAVDMDTLEPVDASSRH---SSSAATAGLCLSHIQELWVRLAWPDPAQAQGLGTQLGQDV 773
GA++ D + +S H S S L+ E+ +L PDP+ + + +
Sbjct: 1086 GALERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTI 1145
Query: 774 CEATLFYTELLRKKVDTQPGAAGEAVSEAL-CVVLNNVELVRKAAGQALKGLAWPEGATG 832
+ + Y ++L K E L C+++NNV+ +R + + + E
Sbjct: 1146 GKVLMQYADILSKDFPAY------CTKEKLPCILMNNVQQLRVQLEKMFEAMGGKELDLE 1199
Query: 833 PEGVLPRPLLSCTQALDDDLQREAHTVTAHLTS--KMVGDIRKYVQHI-SLSPDSIQN-- 887
L + LD+ ++ + + + DI V+ + SPD+ +
Sbjct: 1200 AADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDARASAA 1259
Query: 888 ---DEAVAPLMKYLDEKLALLNASLVKGNLSRVLEALWELLLQAILQAL----------- 933
D + PLM +LD L L K L RVL+ LW +++ + + +
Sbjct: 1260 QDADSVLRPLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTDQTGT 1319
Query: 934 ----------------------GANRDVSADFYSRFHFTLEALVSFFHAEGQGLPLESL- 970
R+++ + L+ + +FHA G GL L
Sbjct: 1320 QLIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVLDLALDTIKQYFHAGGNGLKKTFLE 1379
Query: 971 RDGSYKRLKEELRLHKCSTRECIEQFYLDKLKQRTLEQNRFGRLSVR----CHYEAAEQR 1026
+ + L+ L L+ +T I+ F + Q + + G +S++ H E +
Sbjct: 1380 KSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQGSGVDDPVGEVSIQVDLFTHPGTGEHK 1439
Query: 1027 LAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTRTLHPVYDELFYF 1085
+ V+V+ A D L G+ PFV V + PH R T+ K+ P Y+E F+F
Sbjct: 1440 VTVKVVAAND-LKWQTAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHF 1497
Score = 32.3 bits (72), Expect = 2.8
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 12/82 (14%)
Query: 1026 RLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTRTLHPVYDELFYF 1085
++ + V+ A L D G SDP+V V++ +RT+ L+PV++E F+F
Sbjct: 601 KITITVVCAQGLQAKDKTGSSDPYVTVQVSKT-------KKRTKTIFGNLNPVWEEKFHF 653
Query: 1086 SVPAEACRRRAACVLFTVMDHD 1107
C + + V D D
Sbjct: 654 E-----CHNSSDRIKVRVWDED 670
>gi|122937514 unc-13 homolog C [Homo sapiens]
Length = 2214
Score = 109 bits (272), Expect = 2e-23
Identities = 246/1197 (20%), Positives = 444/1197 (37%), Gaps = 212/1197 (17%)
Query: 98 GEGRQGLPCLEVPLRSGSPAPPEPVDPSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPD 157
G RQG+ CLE ++ + + + L+ A + + E+ T++
Sbjct: 1120 GIARQGMKCLECGVKCHEKC--QDLLNADCLQRAAEKSSKHGAEDKTQTIITAMKERMKI 1177
Query: 158 QVDDEEALLSYLQQVFGTSLEEHTEAIERVRKAKAP-----TYALKVSVMRAKNLLAKDP 212
+ + + +Q++F S E+ + + +++ + + ++V+ A+ L AKD
Sbjct: 1178 REKNRPEVFEVIQEMFQISKEDFVQFTKAAKQSVLDGTSKWSAKITITVVSAQGLQAKDK 1237
Query: 213 NGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPV 272
G SDPY + + K +R T+ LNPV
Sbjct: 1238 TGSSDPYVTVQV--------------------GKNKRR-----------TKTIFGNLNPV 1266
Query: 273 WKEHFLFEIEDVSTDQLHLDIWDHDDDVSLVEACRKLNEVIGLKGMGRYFKQIVKSARAN 332
W E F FE + STD++ + +WD DDD+ + ++FK+
Sbjct: 1267 WDEKFYFECHN-STDRIKVRVWDEDDDIK--------------SRVKQHFKK-------- 1303
Query: 333 GTAGPTEDHTDDFLGCLNIPVREVPVAGVDRWFKLEPRSSASRVQGHCHLVLKLITTQRD 392
+DDFLG + VR + +D W+ LE R+ S V G L + + +
Sbjct: 1304 --------ESDDFLGQTIVEVRTLS-GEMDVWYNLEKRTDKSAVSGAIRLKINVEIKGEE 1354
Query: 393 TAMSQRGRSGFLSHLLLLSHLLRLEHSA-----EEPNSSSWRGELSTPAATILCLHGAQS 447
+ L H L +L ++ + E +W+ + I+ +
Sbjct: 1355 KVAPYHIQYTCL-HENLFHYLTEVKSNGGVKIPEVKGDEAWKVFFDDASQEIVDEFAMRY 1413
Query: 448 NLSPLQLAVLHWQVSSRHHQTCTLD--YSYLLGLLEDMQAHWEEAPSLPQEQEESLADSL 505
+ + A+ H+ S + + S LL + AH + ++ + A +
Sbjct: 1414 GIESIYQAMTHFSCLSSKYMCPGVPAVMSTLLANINAFYAHTTVSTNIQVSASDRFAATN 1473
Query: 506 SAFSEFGLQLLRQL-----------RDYFPATNSTAVHRLELLLKCLGKLQLFQP---SF 551
+F ++LL QL R+ FPA+N+ + L+ + L + F+
Sbjct: 1474 FGREKF-IKLLDQLHNSLRIDLSKYRENFPASNTERLQDLKSTVDLLTSITFFRMKVLEL 1532
Query: 552 EICPFESELNMD-IAAALKRGNREWYDRI------LNDKS-----PREQPGPQR-----L 594
+ P S + D + A L + +D L D S PRE GP
Sbjct: 1533 QSPPKASMVVKDCVRACLDSTYKYIFDNCHELYSQLTDPSKKQDIPREDQGPTTKNLDFW 1592
Query: 595 PGLVVLADAVYDDLQFCYSVYASLFHSILNVDVFTLTFRQLERLVAEEAWVLTEELSPKM 654
P L+ L + D+ + Y+ + F LN + ++ AE W L L K
Sbjct: 1593 PQLITLMVTIIDEDKTAYTPVLNQFPQELN----------MGKISAEIMWTLF-ALDMKY 1641
Query: 655 TLE--------VASGLFELYLT--------LADLQRFWDSIPGRDSRSLALAGIHAPFLP 698
LE ++ L+ + +L F D++P SL F P
Sbjct: 1642 ALEEHENQRLCKSTDYMNLHFKVKWFYNEYVRELPAFKDAVP---EYSLW-------FEP 1691
Query: 699 AVKLWFQVLRDQAKWRLQGAVDMDTLEPVDASSRH---SSSAATAGLCLSHIQELWVRLA 755
V W D + L GA+ D + +S H S S L+ E+ +L
Sbjct: 1692 FVMQWLDENEDVSMEFLHGALGRDKKDGFQQTSEHALFSCSVVDVFAQLNQSFEIIKKLE 1751
Query: 756 WPDPAQAQGLGTQLGQDVCEATLFYTELLRKKVDTQPGAAGEAVSEALCVVLNNVELVRK 815
P+P L + + + + L Y ++ D E V C+++NN++ +R
Sbjct: 1752 CPNPEALSHLMRRFAKTINKVLLQYAAIVSS--DFSSHCDKENVP---CILMNNIQQLRV 1806
Query: 816 AAGQALKGLAWPEGATGPEGVLPRPLLSCTQALDDDLQREAHTVTAHLTSKMVGDIRKYV 875
+ + + E + +L + + LD+ + + + + + +
Sbjct: 1807 QLEKMFESMGGKELDSEASTILKELQVKLSGVLDELSVTYGESFQV-IIEECIKQMSFEL 1865
Query: 876 QHISLSPDSIQNDEAVA--------PLMKYLDEKLALLNASLVKGNLSRVLEALWELLL- 926
+ + ++ N + A LM +LD+ L+L K L RVL+ LW+L+L
Sbjct: 1866 NQMRANGNTTSNKNSAAMDAEIVLRSLMDFLDKTLSLSAKICEKTVLKRVLKELWKLVLN 1925
Query: 927 ----QAILQALG----------ANRDVSADFYSRFHF------------------TLEAL 954
Q +L L A +D+ + H L +
Sbjct: 1926 KIEKQIVLPPLTDQTGPQMIFIAAKDLGQLSKLKEHMIREDARGLTPRQCAIMEVVLATI 1985
Query: 955 VSFFHAEGQGLPLESL-RDGSYKRLKEELRLHKCSTRECIEQFYLDKLKQRTLEQNRFGR 1013
+FHA G GL L + + L+ L L+ +T I++F + Q ++ G+
Sbjct: 1986 KQYFHAGGNGLKKNFLEKSPDLQSLRYALSLYTQTTDALIKKFIDTQTSQSRSSKDAVGQ 2045
Query: 1014 LSVRCHYEA----AEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQ 1069
+SV A + ++ V+V+ D L + PFV V + P+L R Q T+
Sbjct: 2046 ISVHVDITATPGTGDHKVTVKVIAIND-LNWQTTAMFRPFVEVCILGPNLGDKKRKQGTK 2104
Query: 1070 VKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVTGVA 1129
K+ T P Y+E F F + E R A + +V D+ + + G + L +
Sbjct: 2105 TKSNTWSPKYNETFQFILGKEN-RPGAYELHLSVKDYCFAREDRIIGMTVIQLQNIA--- 2160
Query: 1130 RPQVGGGARAGQPVTLHLCRPRAQVRSALRRLEGRTSKE-AQEFVKKLKELEKCMEA 1185
G A P+ ++ + + LR L RTS + A+EFV+ E E+
Sbjct: 2161 ---EKGSYGAWYPLLKNISMDETGL-TILRILSQRTSDDVAKEFVRLKSETRSTEES 2213
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 92.8 bits (229), Expect = 2e-18
Identities = 168/832 (20%), Positives = 310/832 (37%), Gaps = 153/832 (18%)
Query: 165 LLSYLQQVFGTSLEEHTEAIERVRKAKAP-----TYALKVSVMRAKNLLAKDPNGFSDPY 219
+ +Q++F + HT+ ++ V+++ + + ++V+ A+ L AKD G SDPY
Sbjct: 729 IFELIQEIFAVTKTAHTQQMKAVKQSVLDGTSKWSAKISITVVCAQGLQAKDKTGSSDPY 788
Query: 220 CMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLF 279
+ + K KR T+ LNPVW+E+F F
Sbjct: 789 VTVQV--------------------GKTKKR-----------TKTIYGNLNPVWEENFHF 817
Query: 280 EIEDVSTDQLHLDIWDHDDDVSLVEACRKLNEVIGLKGMGRYFKQIVKSARANGTAGPTE 339
E + S+D++ + +WD DDD+ + + FK+
Sbjct: 818 ECHN-SSDRIKVRVWDEDDDIK--------------SRVKQRFKR--------------- 847
Query: 340 DHTDDFLGCLNIPVREVPVAGVDRWFKLEPRSSASRVQGHCHLVLKLITTQRDTAMSQRG 399
+DDFLG I VR + +D W+ L+ R+ S V G L + + +
Sbjct: 848 -ESDDFLGQTIIEVRTLS-GEMDVWYNLDKRTDKSAVSGAIRLHISVEIKGEEKVAPYHV 905
Query: 400 RSGFLSHLLLLSHLLRLEHSA-----EEPNSSSWRGELSTPAATILCLHGAQSNLSPLQL 454
+ L H L + ++++ + +W+ A I+ + + +
Sbjct: 906 QYTCL-HENLFHFVTDVQNNGVVKIPDAKGDDAWKVYYDETAQEIVDEFAMRYGVESIYQ 964
Query: 455 AVLHWQVSSRHHQTCTLDYSYLLGLLEDMQAHWEEAPSLPQEQEESLADSLSAFSEFG-- 512
A+ H+ S + C + + LL ++ A++ + S +D +A S FG
Sbjct: 965 AMTHFACLSSKYM-CPGVPAVMSTLLANINAYYAHTTA---STNVSASDRFAA-SNFGKE 1019
Query: 513 --LQLLRQL-----------RDYFPATNSTAVHRLELLLKCLGKLQLFQPSFEICPFESE 559
++LL QL R+ FPA++ + L+ + L + F+ +
Sbjct: 1020 RFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQDLKSTVDLLTSITFFRMKVQELQSPPR 1079
Query: 560 LNMDIAAALKRGNREWYDRILN------------------DKSPREQ-PGPQRLP---GL 597
+ + +K Y+ I N + P EQ P + L L
Sbjct: 1080 ASQVVKDCVKACLNSTYEYIFNNCHELYSREYQTDPAKKGEVLPEEQGPSIKNLDFWSKL 1139
Query: 598 VVLADAVYDDLQFCYSVYASLFHSILNVDVFTLTFRQLERLVAEEAWVLTEELSPKMTLE 657
+ L ++ ++ + Y+ + F LNV ++ + L A++ EE +
Sbjct: 1140 ITLIVSIIEEDKNSYTPCLNQFPQELNVG--KISAEVMWNLFAQDMKYAMEEHDKHRLCK 1197
Query: 658 VAS---------GLFELYLTLADLQRFWDSIPGRDSRSLALAGIHAPFLPAVKLWFQVLR 708
A L+ Y+T +L F D +P A F P V W
Sbjct: 1198 SADYMNLHFKVKWLYNEYVT--ELPAFKDRVPEYP----------AWFEPFVIQWLDENE 1245
Query: 709 DQAKWRLQGAVDMDTLEPVDASSRH---SSSAATAGLCLSHIQELWVRLAWPDPAQAQGL 765
+ ++ L GA++ D + +S H S S L+ E+ +L PDP
Sbjct: 1246 EVSRDFLHGALERDKKDGFQQTSEHALFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHY 1305
Query: 766 GTQLGQDVCEATLFYTELLRKKVDTQPGAAGEAVSEALCVVLNNVELVRKAAGQALKGLA 825
+ + + L Y +++ K + E V C+++NN + +R + + +
Sbjct: 1306 MRRFAKTISNVLLQYADIISKDFASYCSKEKEKVP---CILMNNTQQLRVQLEKMFEAMG 1362
Query: 826 WPEGATGPEGVLPRPLLSCTQALDDDLQREAHTVTAHLTS--KMVGDIRKYVQHISLSPD 883
E +L + LD+ + A + H+ K +GDI V+ P
Sbjct: 1363 GKELDAEASDILKELQVKLNNVLDELSRVFATSFQPHIEECVKQMGDILSQVKGTGNVPA 1422
Query: 884 SIQN------DEAVAPLMKYLDEKLALLNASLVKGNLSRVLEALWELLLQAI 929
S + D + P+M LD L L K L RVL+ LW+L++ +
Sbjct: 1423 SACSSVAQDADNVLQPIMDLLDSNLTLFAKICEKTVLKRVLKELWKLVMNTM 1474
Score = 49.7 bits (117), Expect = 2e-05
Identities = 44/157 (28%), Positives = 71/157 (45%), Gaps = 9/157 (5%)
Query: 951 LEALVSFFHAEGQGLPLESL-RDGSYKRLKEELRLHKCSTRECIEQFYLDKLKQRTLEQN 1009
L+ + +FHA G GL L + + L+ L L+ +T I+ F + Q ++
Sbjct: 1554 LDTIKQYFHAGGVGLKKTFLEKSPDLQSLRYALSLYTQATDLLIKTFVQTQSAQGLGVED 1613
Query: 1010 RFGRLSVRC----HYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRS 1065
G +SV H E ++ V+V+ A DL +G+ PF+ V + P L R
Sbjct: 1614 PVGEVSVHVELFTHPGTGEHKVTVKVVAANDL-KWQTSGIFRPFIEVNIIGPQLSDKKRK 1672
Query: 1066 QRTQVKTRTLHPVYDELFYFSVPAEA---CRRRAACV 1099
T+ K + P Y+E F F++ A+A C CV
Sbjct: 1673 FATKSKNNSWAPKYNESFQFTLSADAGPECYELQVCV 1709
Score = 35.0 bits (79), Expect = 0.42
Identities = 32/132 (24%), Positives = 57/132 (43%), Gaps = 14/132 (10%)
Query: 978 LKEELRLHKCSTRECIE--QFYLDKLKQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAA 1035
LK+ +++ + + E E Q K +Q + + SV ++++ V+ A
Sbjct: 715 LKDRMKIRERNKPEIFELIQEIFAVTKTAHTQQMKAVKQSVLDGTSKWSAKISITVVCAQ 774
Query: 1036 DLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRR 1095
L D G SDP+V V++G +RT+ L+PV++E F+F C
Sbjct: 775 GLQAKDKTGSSDPYVTVQVGKT-------KKRTKTIYGNLNPVWEENFHFE-----CHNS 822
Query: 1096 AACVLFTVMDHD 1107
+ + V D D
Sbjct: 823 SDRIKVRVWDED 834
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 69.3 bits (168), Expect = 2e-11
Identities = 50/150 (33%), Positives = 71/150 (47%), Gaps = 5/150 (3%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQ 1066
EQ + G + Y +L V VL A +L +D GLSDP+V V L VR +
Sbjct: 236 EQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGG--KKVRKK 293
Query: 1067 RTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVT 1126
+T +K TL+P Y+E F F VP + ++ V TV+D+D L N+ G A+G
Sbjct: 294 KTTIKKNTLNPYYNEAFSFEVPCDQVQK--VQVELTVLDYDKLGKNEAIGRVAVGAAAGG 351
Query: 1127 GVARPQVGGGARAGQPVT-LHLCRPRAQVR 1155
R A +P+ H RP +VR
Sbjct: 352 AGLRHWADMLANPRRPIAQWHSLRPPDRVR 381
Score = 59.3 bits (142), Expect = 2e-08
Identities = 49/172 (28%), Positives = 77/172 (44%), Gaps = 21/172 (12%)
Query: 968 ESLRDGSYKRLKEELRLHKCSTRECIEQFYLDKLK--------------QRTLEQNRFGR 1013
+S R + K+ + + ++H + + Q Y+DK++ Q+ +++ GR
Sbjct: 53 KSCRRRTGKKSQAQAQVHLQEVKG-LGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGR 111
Query: 1014 LSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTR 1073
L Y+ +L V +L A L LD G SDP+V V L P R T+V +
Sbjct: 112 LQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKR----RRYETKVHRQ 167
Query: 1074 TLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGV 1125
TL+P + E F F VP R ++ V D D S ND GE + + V
Sbjct: 168 TLNPHFGETFAFKVPYVELGGRV--LVMAVYDFDRFSRNDAIGEVRVPMSSV 217
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 28/103 (27%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V V+ AKNL D G SDPY + +L R+ +
Sbjct: 256 LTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKK--------------------- 294
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T +K +TLNP + E F FE+ + V Q+ L + D+D
Sbjct: 295 -----TTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYD 332
Score = 31.6 bits (70), Expect = 4.7
Identities = 43/165 (26%), Positives = 66/165 (40%), Gaps = 36/165 (21%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V +++A L A D G SDPY + +LP K +R+
Sbjct: 125 LLVGILQAMGLAALDLGGSSDPYVRVYLLP----------DKRRRYE------------- 161
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHD-DDVSLVEACRKLNEVIGL 315
T+V TLNP + E F F++ V L + +D D S +A ++ +
Sbjct: 162 -----TKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSS 216
Query: 316 KGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVREVPVAG 360
+GR + A A P E+ + LG + +R VP AG
Sbjct: 217 VDLGRPVQ-----AWRELQAAPREE--QEKLGDICFSLRYVPTAG 254
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 68.2 bits (165), Expect = 5e-11
Identities = 41/110 (37%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
Query: 1012 GRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVK 1071
G L + +Y + RL V+V+ A LL D + SDPFV ++L H LV++++T
Sbjct: 323 GELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQL--VHGLKLVKTKKTSFL 380
Query: 1072 TRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALG 1121
T+ P Y+E F F VP E A ++FTV H+ S+NDF G +G
Sbjct: 381 RGTIDPFYNESFSFKVPQEELEN--ASLVFTVFGHNMKSSNDFIGRIVIG 428
Score = 47.0 bits (110), Expect = 1e-04
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 13/127 (10%)
Query: 1003 QRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLP-LDANGL------SDPFVIVELG 1055
+ L + + G L Y+ L V V+ A DL P + +G S+P+V + L
Sbjct: 177 EEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLL 236
Query: 1056 PPHLFPLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFA 1115
P S++T VK +T PV++E + F +P +RR +L TV+D D S +
Sbjct: 237 PDQK----NSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRT--LLLTVVDFDKFSRHCVI 290
Query: 1116 GEAALGL 1122
G+ ++ L
Sbjct: 291 GKVSVPL 297
Score = 32.0 bits (71), Expect = 3.6
Identities = 40/182 (21%), Positives = 72/182 (39%), Gaps = 55/182 (30%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V V+RAK LL D + SDP+ + ++ + K ++ F +G
Sbjct: 338 LNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGL------KLVKTKKTSFLRG--------- 382
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHDDDVSLVEACRKLNEVIG 314
T++P + E F F++ E++ L ++ H+ + N+ IG
Sbjct: 383 -----------TIDPFYNESFSFKVPQEELENASLVFTVFGHN--------MKSSNDFIG 423
Query: 315 LKGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVREVPVAGVDRWFKLEPRSSAS 374
+G+Y ++GP+E T+ + LN V++W L R+
Sbjct: 424 RIVIGQY------------SSGPSE--TNHWRRMLN-----THRTAVEQWHSLRSRAECD 464
Query: 375 RV 376
RV
Sbjct: 465 RV 466
Score = 31.2 bits (69), Expect = 6.1
Identities = 56/240 (23%), Positives = 95/240 (39%), Gaps = 48/240 (20%)
Query: 101 RQGLPCLEV-PLRSGS-PAPPEPVDPSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPDQ 158
R P +++ P+ G A EP+ PS+ R P++ +E LY++ + + D
Sbjct: 116 RPSSPLIDIKPIEFGVLSAKKEPIQPSVLRRTYNPDDYFRKFEPHLYSL--DSNSDDVDS 173
Query: 159 VDDEEALLSYLQQVFGTSLEE---HTEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGF 215
+ DEE L Y + S + H RV +A+ + R
Sbjct: 174 LTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSR-------QDMAH 226
Query: 216 SDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKE 275
S+PY + +LP +K SK+ G VK T PV++E
Sbjct: 227 SNPYVKICLLPD-----------------QKNSKQTG-----------VKRKTQKPVFEE 258
Query: 276 HFLFEIEDVSTDQ--LHLDIWDHDD---DVSLVEACRKLNEVIGLKGMGRYFKQIVKSAR 330
+ FEI + + L L + D D + + L EV +KG G ++K ++ S++
Sbjct: 259 RYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKG-GHWWKALIPSSQ 317
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 67.8 bits (164), Expect = 6e-11
Identities = 48/148 (32%), Positives = 77/148 (52%), Gaps = 10/148 (6%)
Query: 976 KRLKEELRLHKCSTRECIE-QFYLDKLKQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHA 1034
K+LK H + C+E Q +DK + ++LE+ GR+ + Y + +Q L V ++
Sbjct: 236 KKLKPN---HTKTFNICLEKQLPVDKTEDKSLEER--GRILISLKYSSQKQGLLVGIVRC 290
Query: 1035 ADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRR 1094
A L +DANG SDP+V L P +T VK +TL+P ++E F + + +
Sbjct: 291 AHLAAMDANGYSDPYVKTYLRPD--VDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAK 348
Query: 1095 RAACVLFTVMDHDWLSTNDFAGEAALGL 1122
++ V TV D+D +NDF G LG+
Sbjct: 349 KSLEV--TVWDYDIGKSNDFIGGVVLGI 374
Score = 48.9 bits (115), Expect = 3e-05
Identities = 38/124 (30%), Positives = 54/124 (43%), Gaps = 29/124 (23%)
Query: 176 SLEEHTEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPR 235
SLEE + + K + L V ++R +L A D NG+SDPY + P D
Sbjct: 263 SLEERGRILISL-KYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVD------ 315
Query: 236 AQKEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFEIE--DVSTDQLHLDI 293
K SK T VK TLNP + E F +EI+ D++ L + +
Sbjct: 316 ----------KKSKHK----------TAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTV 355
Query: 294 WDHD 297
WD+D
Sbjct: 356 WDYD 359
Score = 46.2 bits (108), Expect = 2e-04
Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 1012 GRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVK 1071
G L Y+ L + A L P+D NGL+DP+V + L P RT+
Sbjct: 128 GTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPG--ASKANKLRTKTL 185
Query: 1072 TRTLHPVYDE-LFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGL 1122
TL+P ++E L Y+ + E R+ + +V D D N+F GE + L
Sbjct: 186 RNTLNPTWNETLTYYGITDEDMIRKT--LRISVCDEDKFRHNEFIGETRVPL 235
Score = 38.1 bits (87), Expect = 0.050
Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 29/105 (27%)
Query: 196 ALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLP 255
AL ++ +AK L D NG +DPY L +LP + + R
Sbjct: 142 ALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLR-------------------- 181
Query: 256 AKCIQVTEVKSSTLNPVWKE---HFLFEIEDVSTDQLHLDIWDHD 297
T+ +TLNP W E ++ ED+ L + + D D
Sbjct: 182 ------TKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDED 220
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 66.6 bits (161), Expect = 1e-10
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 8/110 (7%)
Query: 1012 GRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVK 1071
GR+S Y +L V +L A DL D+NG SDP+V + L P + +T+V
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDR----KKKFQTKVH 356
Query: 1072 TRTLHPVYDELFYFSVP-AEACRRRAACVLFTVMDHDWLSTNDFAGEAAL 1120
+TL+PV++E F FSVP AE +R+ + F+V D D S +D G+ L
Sbjct: 357 RKTLNPVFNETFQFSVPLAELAQRK---LHFSVYDFDRFSRHDLIGQVVL 403
Score = 50.8 bits (120), Expect = 7e-06
Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 4/115 (3%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQ 1066
E+ G L+ Y RL V ++ A++L +D G SDP+V L ++ +
Sbjct: 428 EKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR--RLKKR 485
Query: 1067 RTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALG 1121
+T +K TL+P Y+E F V E+ + V+D+D + N+ G +G
Sbjct: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSI--AVVDYDCIGHNEVIGVCRVG 538
Score = 46.6 bits (109), Expect = 1e-04
Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 30/103 (29%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V +++A +L AKD NGFSDPY + +LP R +K Q
Sbjct: 316 LVVRILQALDLPAKDSNGFSDPYVKIYLLP-------DRKKKFQ---------------- 352
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T+V TLNPV+ E F F + +++ +LH ++D D
Sbjct: 353 -----TKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFD 390
Score = 46.2 bits (108), Expect = 2e-04
Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 32/123 (26%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V++++A NL A D GFSDPY ++ E R K+++
Sbjct: 448 LTVTIIKASNLKAMDLTGFSDPYVKASLI------SEGRRLKKRK--------------- 486
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHDDDVSLVEACRKLNEVIGLK 316
T +K +TLNP + E +F++ S + + L I D D C NEVIG+
Sbjct: 487 -----TSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD------CIGHNEVIGVC 535
Query: 317 GMG 319
+G
Sbjct: 536 RVG 538
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 66.6 bits (161), Expect = 1e-10
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 8/110 (7%)
Query: 1012 GRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVK 1071
GR+S Y +L V +L A DL D+NG SDP+V + L P + +T+V
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDR----KKKFQTKVH 356
Query: 1072 TRTLHPVYDELFYFSVP-AEACRRRAACVLFTVMDHDWLSTNDFAGEAAL 1120
+TL+PV++E F FSVP AE +R+ + F+V D D S +D G+ L
Sbjct: 357 RKTLNPVFNETFQFSVPLAELAQRK---LHFSVYDFDRFSRHDLIGQVVL 403
Score = 50.8 bits (120), Expect = 7e-06
Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 4/115 (3%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQ 1066
E+ G L+ Y RL V ++ A++L +D G SDP+V L ++ +
Sbjct: 428 EKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR--RLKKR 485
Query: 1067 RTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALG 1121
+T +K TL+P Y+E F V E+ + V+D+D + N+ G +G
Sbjct: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSI--AVVDYDCIGHNEVIGVCRVG 538
Score = 46.6 bits (109), Expect = 1e-04
Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 30/103 (29%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V +++A +L AKD NGFSDPY + +LP R +K Q
Sbjct: 316 LVVRILQALDLPAKDSNGFSDPYVKIYLLP-------DRKKKFQ---------------- 352
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T+V TLNPV+ E F F + +++ +LH ++D D
Sbjct: 353 -----TKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFD 390
Score = 46.2 bits (108), Expect = 2e-04
Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 32/123 (26%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V++++A NL A D GFSDPY ++ E R K+++
Sbjct: 448 LTVTIIKASNLKAMDLTGFSDPYVKASLI------SEGRRLKKRK--------------- 486
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHDDDVSLVEACRKLNEVIGLK 316
T +K +TLNP + E +F++ S + + L I D D C NEVIG+
Sbjct: 487 -----TSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD------CIGHNEVIGVC 535
Query: 317 GMG 319
+G
Sbjct: 536 RVG 538
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 66.6 bits (161), Expect = 1e-10
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 8/110 (7%)
Query: 1012 GRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVK 1071
GR+S Y +L V +L A DL D+NG SDP+V + L P + +T+V
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDR----KKKFQTKVH 356
Query: 1072 TRTLHPVYDELFYFSVP-AEACRRRAACVLFTVMDHDWLSTNDFAGEAAL 1120
+TL+PV++E F FSVP AE +R+ + F+V D D S +D G+ L
Sbjct: 357 RKTLNPVFNETFQFSVPLAELAQRK---LHFSVYDFDRFSRHDLIGQVVL 403
Score = 50.8 bits (120), Expect = 7e-06
Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 4/115 (3%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQ 1066
E+ G L+ Y RL V ++ A++L +D G SDP+V L ++ +
Sbjct: 428 EKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGR--RLKKR 485
Query: 1067 RTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALG 1121
+T +K TL+P Y+E F V E+ + V+D+D + N+ G +G
Sbjct: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSI--AVVDYDCIGHNEVIGVCRVG 538
Score = 46.6 bits (109), Expect = 1e-04
Identities = 33/103 (32%), Positives = 49/103 (47%), Gaps = 30/103 (29%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V +++A +L AKD NGFSDPY + +LP R +K Q
Sbjct: 316 LVVRILQALDLPAKDSNGFSDPYVKIYLLP-------DRKKKFQ---------------- 352
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T+V TLNPV+ E F F + +++ +LH ++D D
Sbjct: 353 -----TKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFD 390
Score = 46.2 bits (108), Expect = 2e-04
Identities = 36/123 (29%), Positives = 55/123 (44%), Gaps = 32/123 (26%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V++++A NL A D GFSDPY ++ E R K+++
Sbjct: 448 LTVTIIKASNLKAMDLTGFSDPYVKASLI------SEGRRLKKRK--------------- 486
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHDDDVSLVEACRKLNEVIGLK 316
T +K +TLNP + E +F++ S + + L I D D C NEVIG+
Sbjct: 487 -----TSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD------CIGHNEVIGVC 535
Query: 317 GMG 319
+G
Sbjct: 536 RVG 538
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 65.5 bits (158), Expect = 3e-10
Identities = 38/115 (33%), Positives = 61/115 (53%), Gaps = 4/115 (3%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQ 1066
EQ + G + Y +L V +L A +L +D GLSDP+V + L ++ +
Sbjct: 270 EQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHL--MQNGKRLKKK 327
Query: 1067 RTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALG 1121
+T +K TL+P Y+E F F VP E ++ V+ TV+D+D + ND G+ +G
Sbjct: 328 KTTIKKNTLNPYYNESFSFEVPFEQIQK--VQVVVTVLDYDKIGKNDAIGKVFVG 380
Score = 60.1 bits (144), Expect = 1e-08
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 6/116 (5%)
Query: 1002 KQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFP 1061
K+ E+ + G+L Y+ +L V ++ AA+L LD G SDP+V V L P
Sbjct: 134 KEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDK--- 190
Query: 1062 LVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGE 1117
+ T+V +TL+PV++E F F VP + ++ V D D S +D GE
Sbjct: 191 -KKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKT--LVMAVYDFDRFSKHDIIGE 243
Score = 39.7 bits (91), Expect = 0.017
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 28/103 (27%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V ++ AKNL D G SDPY + ++ Q +R +K
Sbjct: 290 LTVVILEAKNLKKMDVGGLSDPYVKIHLM-----------QNGKRLKKKK---------- 328
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T +K +TLNP + E F FE+ E + Q+ + + D+D
Sbjct: 329 -----TTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 366
Score = 35.0 bits (79), Expect = 0.42
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 30/103 (29%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V +++A L A D G SDPY + +LP K+++F
Sbjct: 159 LLVGIIQAAELPALDMGGTSDPYVKVFLLP----------DKKKKF-------------- 194
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T+V TLNPV+ E F F++ ++ L + ++D D
Sbjct: 195 ----ETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFD 233
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 65.5 bits (158), Expect = 3e-10
Identities = 38/115 (33%), Positives = 61/115 (53%), Gaps = 4/115 (3%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQ 1066
EQ + G + Y +L V +L A +L +D GLSDP+V + L ++ +
Sbjct: 270 EQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHL--MQNGKRLKKK 327
Query: 1067 RTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALG 1121
+T +K TL+P Y+E F F VP E ++ V+ TV+D+D + ND G+ +G
Sbjct: 328 KTTIKKNTLNPYYNESFSFEVPFEQIQK--VQVVVTVLDYDKIGKNDAIGKVFVG 380
Score = 60.1 bits (144), Expect = 1e-08
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 6/116 (5%)
Query: 1002 KQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFP 1061
K+ E+ + G+L Y+ +L V ++ AA+L LD G SDP+V V L P
Sbjct: 134 KEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDK--- 190
Query: 1062 LVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGE 1117
+ T+V +TL+PV++E F F VP + ++ V D D S +D GE
Sbjct: 191 -KKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKT--LVMAVYDFDRFSKHDIIGE 243
Score = 39.7 bits (91), Expect = 0.017
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 28/103 (27%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V ++ AKNL D G SDPY + ++ Q +R +K
Sbjct: 290 LTVVILEAKNLKKMDVGGLSDPYVKIHLM-----------QNGKRLKKKK---------- 328
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T +K +TLNP + E F FE+ E + Q+ + + D+D
Sbjct: 329 -----TTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 366
Score = 35.0 bits (79), Expect = 0.42
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 30/103 (29%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V +++A L A D G SDPY + +LP K+++F
Sbjct: 159 LLVGIIQAAELPALDMGGTSDPYVKVFLLP----------DKKKKF-------------- 194
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T+V TLNPV+ E F F++ ++ L + ++D D
Sbjct: 195 ----ETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFD 233
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 65.5 bits (158), Expect = 3e-10
Identities = 38/115 (33%), Positives = 61/115 (53%), Gaps = 4/115 (3%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQ 1066
EQ + G + Y +L V +L A +L +D GLSDP+V + L ++ +
Sbjct: 270 EQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHL--MQNGKRLKKK 327
Query: 1067 RTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALG 1121
+T +K TL+P Y+E F F VP E ++ V+ TV+D+D + ND G+ +G
Sbjct: 328 KTTIKKNTLNPYYNESFSFEVPFEQIQK--VQVVVTVLDYDKIGKNDAIGKVFVG 380
Score = 60.1 bits (144), Expect = 1e-08
Identities = 38/116 (32%), Positives = 58/116 (50%), Gaps = 6/116 (5%)
Query: 1002 KQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFP 1061
K+ E+ + G+L Y+ +L V ++ AA+L LD G SDP+V V L P
Sbjct: 134 KEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDK--- 190
Query: 1062 LVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGE 1117
+ T+V +TL+PV++E F F VP + ++ V D D S +D GE
Sbjct: 191 -KKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKT--LVMAVYDFDRFSKHDIIGE 243
Score = 39.7 bits (91), Expect = 0.017
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 28/103 (27%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V ++ AKNL D G SDPY + ++ Q +R +K
Sbjct: 290 LTVVILEAKNLKKMDVGGLSDPYVKIHLM-----------QNGKRLKKKK---------- 328
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T +K +TLNP + E F FE+ E + Q+ + + D+D
Sbjct: 329 -----TTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 366
Score = 35.0 bits (79), Expect = 0.42
Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 30/103 (29%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V +++A L A D G SDPY + +LP K+++F
Sbjct: 159 LLVGIIQAAELPALDMGGTSDPYVKVFLLP----------DKKKKF-------------- 194
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T+V TLNPV+ E F F++ ++ L + ++D D
Sbjct: 195 ----ETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFD 233
>gi|4506067 protein kinase C, alpha [Homo sapiens]
Length = 672
Score = 62.4 bits (150), Expect = 2e-09
Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 28/121 (23%)
Query: 179 EHTEAIERVR-KAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQ 237
+HTE R+ KA+ L V+V AKNL+ DPNG SDPY L ++P +P+ +
Sbjct: 154 DHTEKRGRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIP------DPKNE 207
Query: 238 KEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTD-QLHLDIWDH 296
+Q+ T+ STLNP W E F F+++ D +L ++IWD
Sbjct: 208 SKQK--------------------TKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDW 247
Query: 297 D 297
D
Sbjct: 248 D 248
Score = 57.0 bits (136), Expect = 1e-07
Identities = 40/113 (35%), Positives = 65/113 (57%), Gaps = 11/113 (9%)
Query: 1012 GRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRS-QRTQV 1070
GR+ ++ E A+++L V V A +L+P+D NGLSDP+V ++L P P S Q+T+
Sbjct: 160 GRIYLKA--EVADEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPD---PKNESKQKTKT 214
Query: 1071 KTRTLHPVYDELFYFSV-PAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGL 1122
TL+P ++E F F + P++ RR + + D D + NDF G + G+
Sbjct: 215 IRSTLNPQWNESFTFKLKPSDKDRRLSV----EIWDWDRTTRNDFMGSLSFGV 263
>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sapiens]
Length = 431
Score = 61.6 bits (148), Expect = 4e-09
Identities = 42/130 (32%), Positives = 69/130 (53%), Gaps = 5/130 (3%)
Query: 992 CIEQFYLDKLKQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVI 1051
C+E+ L++++ + G + + Y + + L V VL A L P+DANG SDPFV
Sbjct: 270 CLEKRRLEEVETEVAWEE-CGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVR 328
Query: 1052 VELGPPHLFPLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLST 1111
+ L P +T V +TL+P ++E F++S P E ++ +L +V D+D +
Sbjct: 329 LFLHPN--AGKKSKFKTSVHRKTLNPEFNEEFFYSGPREELAQKT--LLVSVWDYDLGTA 384
Query: 1112 NDFAGEAALG 1121
+DF G LG
Sbjct: 385 DDFIGGVQLG 394
Score = 41.2 bits (95), Expect = 0.006
Identities = 48/193 (24%), Positives = 67/193 (34%), Gaps = 66/193 (34%)
Query: 107 LEVPLRSGSPAPPEPVDPSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPDQVDDEEALL 166
L VPLR P D L R L E E+ +EE + +L L
Sbjct: 252 LRVPLRKLVPNRARSFDICLEKRRLEEVETEVAWEECGHVLLS----------------L 295
Query: 167 SYLQQVFGTSLEEHTEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILP 226
Y Q G L V V+R +L D NG+SDP+ L +
Sbjct: 296 CYSSQQGG----------------------LLVGVLRCAHLAPMDANGYSDPFVRLFL-- 331
Query: 227 ASDATREPRAQKEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFE--IEDV 284
P A K+ +F T V TLNP + E F + E++
Sbjct: 332 ------HPNAGKKSKF------------------KTSVHRKTLNPEFNEEFFYSGPREEL 367
Query: 285 STDQLHLDIWDHD 297
+ L + +WD+D
Sbjct: 368 AQKTLLVSVWDYD 380
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 61.6 bits (148), Expect = 4e-09
Identities = 42/132 (31%), Positives = 63/132 (47%), Gaps = 4/132 (3%)
Query: 1012 GRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVK 1071
G L + Y + + V ++ A +L +D G SDP+V V L + V ++T
Sbjct: 268 GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWL--MYKDKRVEKKKTVTM 325
Query: 1072 TRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVTGVARP 1131
R L+P+++E F F +P E + R ++ TVMD D LS ND G+ L G +
Sbjct: 326 KRNLNPIFNESFAFDIPTE--KLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKH 383
Query: 1132 QVGGGARAGQPV 1143
AR QPV
Sbjct: 384 WKDMIARPRQPV 395
Score = 54.3 bits (129), Expect = 7e-07
Identities = 39/119 (32%), Positives = 58/119 (48%), Gaps = 7/119 (5%)
Query: 1008 QNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQR 1067
+ GR+ Y E L V+++ A +L D +G SDPFV + L P L
Sbjct: 133 RENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKL----E 188
Query: 1068 TQVKTRTLHPVYDELFYF-SVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGV 1125
T+VK + L+P ++E F F P E +R + V+D+D S ND GE ++ L V
Sbjct: 189 TKVKRKNLNPHWNETFLFEGFPYEKVVQR--ILYLQVLDYDRFSRNDPIGEVSIPLNKV 245
Score = 44.7 bits (104), Expect = 5e-04
Identities = 42/146 (28%), Positives = 62/146 (42%), Gaps = 35/146 (23%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V +M+A+ L AKD +G SDP+ + +LP E
Sbjct: 152 LTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLE----------------------- 188
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFE---IEDVSTDQLHLDIWDHD---DDVSLVEACRKLN 310
T+VK LNP W E FLFE E V L+L + D+D + + E LN
Sbjct: 189 -----TKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLN 243
Query: 311 EVIGLKGMGRYFKQIVKSARANGTAG 336
+V L M ++K + + +G+ G
Sbjct: 244 KV-DLTQMQTFWKDLKPCSDGSGSRG 268
Score = 32.0 bits (71), Expect = 3.6
Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 28/101 (27%)
Query: 199 VSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPAKC 258
V++++A+NL A D G SDPY + ++ ++ R +K++
Sbjct: 285 VNIIKARNLKAMDIGGTSDPYVKVWLM-----YKDKRVEKKK------------------ 321
Query: 259 IQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T LNP++ E F F+I E + + + + D D
Sbjct: 322 ---TVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKD 359
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 61.2 bits (147), Expect = 6e-09
Identities = 43/153 (28%), Positives = 73/153 (47%), Gaps = 5/153 (3%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQ 1066
E + G + Y +L V +L A +L +D GLSDP+V + L ++ +
Sbjct: 267 EPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHL--MQNGKRLKKK 324
Query: 1067 RTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVT 1126
+T VK +TL+P ++E F F +P E ++ V+ TV+D+D L N+ G+ +G
Sbjct: 325 KTTVKKKTLNPYFNESFSFEIPFEQIQK--VQVVVTVLDYDKLGKNEAIGKIFVGSNATG 382
Query: 1127 GVARPQVGGGARAGQPVT-LHLCRPRAQVRSAL 1158
R A +P+ H +P +V + L
Sbjct: 383 TELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
Score = 58.5 bits (140), Expect = 4e-08
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQ 1066
E G+L Y+ +L V VL AA+L LD G SDP+V V L P +
Sbjct: 136 EPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK----KKKY 191
Query: 1067 RTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGV 1125
T+V +TL+P ++E F F VP + + ++ + D D S +D GE + + V
Sbjct: 192 ETKVHRKTLNPAFNETFTFKVPYQELGGKT--LVMAIYDFDRFSKHDIIGEVKVPMNTV 248
Score = 40.0 bits (92), Expect = 0.013
Identities = 31/103 (30%), Positives = 44/103 (42%), Gaps = 28/103 (27%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V ++ AKNL D G SDPY + ++ Q +R +K
Sbjct: 287 LTVCILEAKNLKKMDVGGLSDPYVKIHLM-----------QNGKRLKKKK---------- 325
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T VK TLNP + E F FEI E + Q+ + + D+D
Sbjct: 326 -----TTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 61.2 bits (147), Expect = 6e-09
Identities = 43/153 (28%), Positives = 73/153 (47%), Gaps = 5/153 (3%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQ 1066
E + G + Y +L V +L A +L +D GLSDP+V + L ++ +
Sbjct: 267 EPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHL--MQNGKRLKKK 324
Query: 1067 RTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVT 1126
+T VK +TL+P ++E F F +P E ++ V+ TV+D+D L N+ G+ +G
Sbjct: 325 KTTVKKKTLNPYFNESFSFEIPFEQIQK--VQVVVTVLDYDKLGKNEAIGKIFVGSNATG 382
Query: 1127 GVARPQVGGGARAGQPVT-LHLCRPRAQVRSAL 1158
R A +P+ H +P +V + L
Sbjct: 383 TELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
Score = 58.5 bits (140), Expect = 4e-08
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 6/119 (5%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQ 1066
E G+L Y+ +L V VL AA+L LD G SDP+V V L P +
Sbjct: 136 EPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK----KKKY 191
Query: 1067 RTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGV 1125
T+V +TL+P ++E F F VP + + ++ + D D S +D GE + + V
Sbjct: 192 ETKVHRKTLNPAFNETFTFKVPYQELGGKT--LVMAIYDFDRFSKHDIIGEVKVPMNTV 248
Score = 40.0 bits (92), Expect = 0.013
Identities = 31/103 (30%), Positives = 44/103 (42%), Gaps = 28/103 (27%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V ++ AKNL D G SDPY + ++ Q +R +K
Sbjct: 287 LTVCILEAKNLKKMDVGGLSDPYVKIHLM-----------QNGKRLKKKK---------- 325
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T VK TLNP + E F FEI E + Q+ + + D+D
Sbjct: 326 -----TTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 61.2 bits (147), Expect = 6e-09
Identities = 45/137 (32%), Positives = 66/137 (48%), Gaps = 8/137 (5%)
Query: 997 YLDKLKQRTLEQNRF---GRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVE 1053
YL +L+Q Q GR+ + Y + + L V +L A L +D NG SDP+V
Sbjct: 235 YLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTY 294
Query: 1054 LGPPHLFPLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTND 1113
L P +T VK +TL+P ++E F++ + + V TV D+D +ND
Sbjct: 295 LRPD--VDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEV--TVWDYDIGKSND 350
Query: 1114 FAGEAALGLGGVTGVAR 1130
F G +LG G G AR
Sbjct: 351 FIGGVSLG-PGARGEAR 366
Score = 50.8 bits (120), Expect = 7e-06
Identities = 49/173 (28%), Positives = 66/173 (38%), Gaps = 56/173 (32%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V ++R +L A D NG+SDPY + P D K SK
Sbjct: 268 LLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD----------------KKSK------- 304
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEIE--DVSTDQLHLDIWDHDDDVSLVEACRKLNEVIG 314
T VK TLNP + E F +EIE ++T L + +WD+D K N+ IG
Sbjct: 305 ---HKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYD--------IGKSNDFIG 353
Query: 315 LKGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVREVPVAGVDRWFKL 367
+G G G H D L + P A ++RW L
Sbjct: 354 GVSLG------------PGARGEARKHWSDCL--------QQPDAALERWHTL 386
Score = 49.3 bits (116), Expect = 2e-05
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 5/112 (4%)
Query: 1012 GRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVK 1071
G L Y+ A L +L A L P+D NGL+DP+V + L P +T+ +
Sbjct: 91 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGAC--KANKLKTKTQ 148
Query: 1072 TRTLHPVYDE-LFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGL 1122
TL+PV++E L Y + + + + V D D LS N+F GE + L
Sbjct: 149 RNTLNPVWNEDLTYSGITDDDITHKV--LRIAVCDEDKLSHNEFIGEIRVPL 198
Score = 39.3 bits (90), Expect = 0.023
Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 29/104 (27%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L S++RAK L D NG +DPY L +LP G K +K
Sbjct: 106 LHCSILRAKGLKPMDFNGLADPYVKLHLLP----------------GACKANK------- 142
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFE---IEDVSTDQLHLDIWDHD 297
T+ + +TLNPVW E + +D++ L + + D D
Sbjct: 143 ---LKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDED 183
>gi|13384594 protein kinase C, gamma [Homo sapiens]
Length = 697
Score = 60.8 bits (146), Expect = 7e-09
Identities = 51/192 (26%), Positives = 83/192 (43%), Gaps = 70/192 (36%)
Query: 179 EHTEAIERVR-KAKAPTY-ALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRA 236
+HTE R++ + +APT + V+V A+NL+ DPNG SDPY L ++P +PR
Sbjct: 153 DHTERRGRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLIP------DPRN 206
Query: 237 QKEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTD-QLHLDIWD 295
+Q+ T +TLNPVW E F+F ++ + +L +++WD
Sbjct: 207 LTKQK--------------------TRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWD 246
Query: 296 HDDDVSLVEACRKLNEVIGLKGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVRE 355
D +++R +DF+G ++ V E
Sbjct: 247 WD-----------------------------RTSR------------NDFMGAMSFGVSE 265
Query: 356 VPVAGVDRWFKL 367
+ A VD W+KL
Sbjct: 266 LLKAPVDGWYKL 277
Score = 58.5 bits (140), Expect = 4e-08
Identities = 40/113 (35%), Positives = 61/113 (53%), Gaps = 6/113 (5%)
Query: 1010 RFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQ 1069
R GRL + A++ + V V A +L+P+D NGLSDP+V ++L P + Q+T+
Sbjct: 157 RRGRLQLEIRAPTADE-IHVTVGEARNLIPMDPNGLSDPYVKLKLIPDP--RNLTKQKTR 213
Query: 1070 VKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGL 1122
TL+PV++E F F++ RR + V D D S NDF G + G+
Sbjct: 214 TVKATLNPVWNETFVFNLKPGDVERRLS---VEVWDWDRTSRNDFMGAMSFGV 263
>gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens]
Length = 451
Score = 60.1 bits (144), Expect = 1e-08
Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 4/110 (3%)
Query: 1012 GRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVK 1071
G + + Y + + L V VL A L P+DANG SDPFV + L P +T V
Sbjct: 309 GHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPN--AGKKSKFKTSVH 366
Query: 1072 TRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALG 1121
+TL+P ++E F++S P E ++ +L +V D+D + +DF G LG
Sbjct: 367 RKTLNPEFNEEFFYSGPREELAQKT--LLVSVWDYDLGTADDFIGGVQLG 414
Score = 40.8 bits (94), Expect = 0.008
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 28/103 (27%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V V+R +L D NG+SDP+ L + P A K+ +F
Sbjct: 324 LLVGVLRCAHLAPMDANGYSDPFVRLFL--------HPNAGKKSKF-------------- 361
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFE--IEDVSTDQLHLDIWDHD 297
T V TLNP + E F + E+++ L + +WD+D
Sbjct: 362 ----KTSVHRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYD 400
>gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens]
Length = 451
Score = 60.1 bits (144), Expect = 1e-08
Identities = 39/110 (35%), Positives = 59/110 (53%), Gaps = 4/110 (3%)
Query: 1012 GRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVK 1071
G + + Y + + L V VL A L P+DANG SDPFV + L P +T V
Sbjct: 309 GHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPN--AGKKSKFKTSVH 366
Query: 1072 TRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALG 1121
+TL+P ++E F++S P E ++ +L +V D+D + +DF G LG
Sbjct: 367 RKTLNPEFNEEFFYSGPREELAQKT--LLVSVWDYDLGTADDFIGGVQLG 414
Score = 40.8 bits (94), Expect = 0.008
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 28/103 (27%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V V+R +L D NG+SDP+ L + P A K+ +F
Sbjct: 324 LLVGVLRCAHLAPMDANGYSDPFVRLFL--------HPNAGKKSKF-------------- 361
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFE--IEDVSTDQLHLDIWDHD 297
T V TLNP + E F + E+++ L + +WD+D
Sbjct: 362 ----KTSVHRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYD 400
>gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]
Length = 671
Score = 59.3 bits (142), Expect = 2e-08
Identities = 50/191 (26%), Positives = 76/191 (39%), Gaps = 69/191 (36%)
Query: 179 EHTEAIERVR-KAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQ 237
+HTE R+ +A L V V AKNL+ DPNG SDPY L ++P +P+++
Sbjct: 154 DHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIP------DPKSE 207
Query: 238 KEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTD-QLHLDIWDH 296
+Q+ T+ +LNP W E F F++++ D +L ++IWD
Sbjct: 208 SKQK--------------------TKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDW 247
Query: 297 DDDVSLVEACRKLNEVIGLKGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVREV 356
D +DF+G L+ + E+
Sbjct: 248 D-----------------------------------------LTSRNDFMGSLSFGISEL 266
Query: 357 PVAGVDRWFKL 367
A VD WFKL
Sbjct: 267 QKASVDGWFKL 277
Score = 53.5 bits (127), Expect = 1e-06
Identities = 39/114 (34%), Positives = 60/114 (52%), Gaps = 9/114 (7%)
Query: 1010 RFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRS-QRT 1068
R GR+ ++ H + L V V A +L+P+D NGLSDP+V ++L P P S Q+T
Sbjct: 158 RRGRIYIQAHID--RDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPD---PKSESKQKT 212
Query: 1069 QVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGL 1122
+ +L+P ++E F F + RR + + D D S NDF G + G+
Sbjct: 213 KTIKCSLNPEWNETFRFQLKESDKDRRLS---VEIWDWDLTSRNDFMGSLSFGI 263
>gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]
Length = 673
Score = 59.3 bits (142), Expect = 2e-08
Identities = 50/191 (26%), Positives = 76/191 (39%), Gaps = 69/191 (36%)
Query: 179 EHTEAIERVR-KAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQ 237
+HTE R+ +A L V V AKNL+ DPNG SDPY L ++P +P+++
Sbjct: 154 DHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIP------DPKSE 207
Query: 238 KEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTD-QLHLDIWDH 296
+Q+ T+ +LNP W E F F++++ D +L ++IWD
Sbjct: 208 SKQK--------------------TKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDW 247
Query: 297 DDDVSLVEACRKLNEVIGLKGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVREV 356
D +DF+G L+ + E+
Sbjct: 248 D-----------------------------------------LTSRNDFMGSLSFGISEL 266
Query: 357 PVAGVDRWFKL 367
A VD WFKL
Sbjct: 267 QKASVDGWFKL 277
Score = 53.5 bits (127), Expect = 1e-06
Identities = 39/114 (34%), Positives = 60/114 (52%), Gaps = 9/114 (7%)
Query: 1010 RFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRS-QRT 1068
R GR+ ++ H + L V V A +L+P+D NGLSDP+V ++L P P S Q+T
Sbjct: 158 RRGRIYIQAHID--RDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPD---PKSESKQKT 212
Query: 1069 QVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGL 1122
+ +L+P ++E F F + RR + + D D S NDF G + G+
Sbjct: 213 KTIKCSLNPEWNETFRFQLKESDKDRRLS---VEIWDWDLTSRNDFMGSLSFGI 263
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 58.9 bits (141), Expect = 3e-08
Identities = 40/121 (33%), Positives = 60/121 (49%), Gaps = 4/121 (3%)
Query: 1001 LKQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLF 1060
+K+ + + G L + Y++ L V VL A L D +GLSDP+V V L H
Sbjct: 278 IKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNL--YHAK 335
Query: 1061 PLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAAL 1120
+ ++T VK T + V++ELF F +P E V F V+D + S N+ G+ L
Sbjct: 336 KRISKKKTHVKKCTPNAVFNELFVFDIPCEGL--EDISVEFLVLDSERGSRNEVIGQLVL 393
Query: 1121 G 1121
G
Sbjct: 394 G 394
Score = 45.8 bits (107), Expect = 2e-04
Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 8/121 (6%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGL-SDPFVIVELGPPHLFPLVRS 1065
+Q + G L Y + V + A L +D + SDP++ + + P +
Sbjct: 150 KQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKV--- 206
Query: 1066 QRTQVKTRTLHPVYDELF-YFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGG 1124
+T+V +TL P +DE F ++ +P + A + FT++ D S +D GE + L G
Sbjct: 207 -KTRVLRKTLDPAFDETFTFYGIPYTQIQELA--LHFTILSFDRFSRDDIIGEVLIPLSG 263
Query: 1125 V 1125
+
Sbjct: 264 I 264
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 58.5 bits (140), Expect = 4e-08
Identities = 35/126 (27%), Positives = 64/126 (50%), Gaps = 4/126 (3%)
Query: 997 YLDKLKQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGP 1056
Y ++ +R + G++ V Y + L V ++ L +DANG SDPFV + L P
Sbjct: 537 YEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKP 596
Query: 1057 PHLFPLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAG 1116
+TQ+K +TL+P ++E F++ + +++ + +V D+D +ND+ G
Sbjct: 597 D--MGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDI--SVWDYDIGKSNDYIG 652
Query: 1117 EAALGL 1122
LG+
Sbjct: 653 GCQLGI 658
Score = 49.7 bits (117), Expect = 2e-05
Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 11/120 (9%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFP-LVRS 1065
E G L Y+ L ++ A L P+D+NGL+DP+V + HL P +S
Sbjct: 389 EATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL-----HLLPGASKS 443
Query: 1066 QRTQVKT--RTLHPVYDE-LFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGL 1122
+ + KT T +P+++E L Y + E +R+ + +V D D N+F GE L
Sbjct: 444 NKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKT--LRISVCDEDKFGHNEFIGETRFSL 501
Score = 47.0 bits (110), Expect = 1e-04
Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 28/103 (27%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V ++R +L A D NG+SDP+ L + P +
Sbjct: 567 LIVGIIRCVHLAAMDANGYSDPFVKLWLKP--------------------------DMGK 600
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEIE--DVSTDQLHLDIWDHD 297
K T++K TLNP + E F ++I+ D++ L + +WD+D
Sbjct: 601 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYD 643
Score = 40.4 bits (93), Expect = 0.010
Identities = 43/198 (21%), Positives = 71/198 (35%), Gaps = 40/198 (20%)
Query: 110 PLRSGSPAPPEPVD-------PSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPDQVDDE 162
P G+ APP P++G R Y +A A P ++E
Sbjct: 319 PSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEE 378
Query: 163 EALLSYLQQVFGTSLEEHTEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCML 222
E + T+L A+E +L+ ++++AK L D NG +DPY L
Sbjct: 379 EEEANSYDSDEATTLG----ALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL 434
Query: 223 GILPASDATREPRAQKEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFE-- 280
+LP + + + R T+ +T NP+W E ++
Sbjct: 435 HLLPGASKSNKLR--------------------------TKTLRNTRNPIWNETLVYHGI 468
Query: 281 -IEDVSTDQLHLDIWDHD 297
ED+ L + + D D
Sbjct: 469 TDEDMQRKTLRISVCDED 486
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 58.5 bits (140), Expect = 4e-08
Identities = 35/126 (27%), Positives = 64/126 (50%), Gaps = 4/126 (3%)
Query: 997 YLDKLKQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGP 1056
Y ++ +R + G++ V Y + L V ++ L +DANG SDPFV + L P
Sbjct: 533 YEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKP 592
Query: 1057 PHLFPLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAG 1116
+TQ+K +TL+P ++E F++ + +++ + +V D+D +ND+ G
Sbjct: 593 D--MGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDI--SVWDYDIGKSNDYIG 648
Query: 1117 EAALGL 1122
LG+
Sbjct: 649 GCQLGI 654
Score = 49.7 bits (117), Expect = 2e-05
Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 11/120 (9%)
Query: 1007 EQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFP-LVRS 1065
E G L Y+ L ++ A L P+D+NGL+DP+V + HL P +S
Sbjct: 385 EATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL-----HLLPGASKS 439
Query: 1066 QRTQVKT--RTLHPVYDE-LFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGL 1122
+ + KT T +P+++E L Y + E +R+ + +V D D N+F GE L
Sbjct: 440 NKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKT--LRISVCDEDKFGHNEFIGETRFSL 497
Score = 47.0 bits (110), Expect = 1e-04
Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 28/103 (27%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V ++R +L A D NG+SDP+ L + P +
Sbjct: 563 LIVGIIRCVHLAAMDANGYSDPFVKLWLKP--------------------------DMGK 596
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEIE--DVSTDQLHLDIWDHD 297
K T++K TLNP + E F ++I+ D++ L + +WD+D
Sbjct: 597 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYD 639
Score = 40.4 bits (93), Expect = 0.010
Identities = 43/198 (21%), Positives = 71/198 (35%), Gaps = 40/198 (20%)
Query: 110 PLRSGSPAPPEPVD-------PSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPDQVDDE 162
P G+ APP P++G R Y +A A P ++E
Sbjct: 315 PSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEE 374
Query: 163 EALLSYLQQVFGTSLEEHTEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCML 222
E + T+L A+E +L+ ++++AK L D NG +DPY L
Sbjct: 375 EEEANSYDSDEATTLG----ALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL 430
Query: 223 GILPASDATREPRAQKEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFE-- 280
+LP + + + R T+ +T NP+W E ++
Sbjct: 431 HLLPGASKSNKLR--------------------------TKTLRNTRNPIWNETLVYHGI 464
Query: 281 -IEDVSTDQLHLDIWDHD 297
ED+ L + + D D
Sbjct: 465 TDEDMQRKTLRISVCDED 482
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 57.8 bits (138), Expect = 6e-08
Identities = 50/159 (31%), Positives = 71/159 (44%), Gaps = 16/159 (10%)
Query: 962 GQGLPLESLRDGSYKRLKEELRLHKCSTRECIEQFYLDKLKQRTLEQNRFGRLSVRCHYE 1021
G LP + + S R+K EL K E D + T G+++ Y+
Sbjct: 106 GNELPPAAEQPTSIGRIKPELYKQKSVDGE-------DAKSEAT---KSCGKINFSLRYD 155
Query: 1022 AAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTRTLHPVYDE 1081
+ L V +L A DL D G SDP+V + L P L +T+V +TL+P +DE
Sbjct: 156 YETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKL----QTRVHRKTLNPTFDE 211
Query: 1082 LFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAAL 1120
F+F VP E R + +V D D S +D GE L
Sbjct: 212 NFHFPVPYEELADRK--LHLSVFDFDRFSRHDMIGEVIL 248
Score = 54.3 bits (129), Expect = 7e-07
Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 4/122 (3%)
Query: 1001 LKQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLF 1060
++ T E G + Y RL + V+ +L +D G SDP+V V L
Sbjct: 267 IQYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGR- 325
Query: 1061 PLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAAL 1120
++ ++T +K TL+PVY+E F +P E +L +VMD+D + N+ G +
Sbjct: 326 -RLKKKKTTIKKNTLNPVYNEAIIFDIPPE--NMDQVSLLISVMDYDRVGHNEIIGVCRV 382
Query: 1121 GL 1122
G+
Sbjct: 383 GI 384
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/106 (30%), Positives = 47/106 (44%), Gaps = 30/106 (28%)
Query: 194 TYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGP 253
T L V +++A +L AKD G SDPY + +LP
Sbjct: 158 TETLIVRILKAFDLPAKDFCGSSDPYVKIYLLP--------------------------- 190
Query: 254 LPAKCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
KC T V TLNP + E+F F + E+++ +LHL ++D D
Sbjct: 191 -DRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFD 235
Score = 42.7 bits (99), Expect = 0.002
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 33/128 (25%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L ++V++ +NL A D G+SDPY + +L + R K+++
Sbjct: 293 LTLTVIKCRNLKAMDITGYSDPYVKVSLL------CDGRRLKKKK--------------- 331
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDI----WDHDDDVSLVEACRKLNEV 312
T +K +TLNPV+ E +F+I + DQ+ L I +D ++ CR
Sbjct: 332 -----TTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCR---VG 383
Query: 313 IGLKGMGR 320
I +G+GR
Sbjct: 384 ITAEGLGR 391
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 57.4 bits (137), Expect = 8e-08
Identities = 40/130 (30%), Positives = 63/130 (48%), Gaps = 6/130 (4%)
Query: 991 ECIEQFYLDKLKQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFV 1050
E +Q LD R G+L+ Y+ ++L V++ A +L D +G SDP+V
Sbjct: 201 ELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYV 260
Query: 1051 IVELGPPHLFPLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLS 1110
+ L P +T+V +TL+PV+DE+F F VP R + F+V D D S
Sbjct: 261 KIYLLPDR----KTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARK--LHFSVYDFDRFS 314
Query: 1111 TNDFAGEAAL 1120
+D G+ +
Sbjct: 315 RHDLIGQVVV 324
Score = 52.0 bits (123), Expect = 3e-06
Identities = 39/132 (29%), Positives = 60/132 (45%), Gaps = 7/132 (5%)
Query: 990 RECIEQFYLDKLKQRTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPF 1049
RECI ++ T + G L Y RL + ++ A +L +D G SDP+
Sbjct: 335 RECI---LWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPY 391
Query: 1050 VIVELGPPHLFPLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWL 1109
V V L ++ ++T K TL+PVY+E F VP E + + VMD+D +
Sbjct: 392 VKVSLMCDGR--RLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSI--AVMDYDRV 447
Query: 1110 STNDFAGEAALG 1121
N+ G +G
Sbjct: 448 GHNEIIGVCQVG 459
Score = 45.1 bits (105), Expect = 4e-04
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 30/119 (25%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L +++++A+NL A D G SDPY + ++ + R K+++
Sbjct: 369 LTITIIKARNLKAMDITGASDPYVKVSLM------CDGRRLKKRK--------------- 407
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDI----WDHDDDVSLVEACRKLNE 311
T K +TLNPV+ E +F++ + DQ+HL I +D ++ C+ NE
Sbjct: 408 -----TSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNE 461
Score = 44.7 bits (104), Expect = 5e-04
Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 30/103 (29%)
Query: 197 LKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKGSKRGGPLPA 256
L V + +A NL AKD +G SDPY + +LP R K Q
Sbjct: 237 LIVKIHKAVNLPAKDFSGTSDPYVKIYLLP-------DRKTKHQ---------------- 273
Query: 257 KCIQVTEVKSSTLNPVWKEHFLFEI--EDVSTDQLHLDIWDHD 297
T+V TLNPV+ E FLF + D+ +LH ++D D
Sbjct: 274 -----TKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFD 311
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,349,676
Number of Sequences: 37866
Number of extensions: 2233885
Number of successful extensions: 7287
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 6678
Number of HSP's gapped (non-prelim): 570
length of query: 1187
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1074
effective length of database: 13,968,660
effective search space: 15002340840
effective search space used: 15002340840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.