Search of human proteins with 154355002

Search of human proteins with 154355002

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154355002 strawberry notch homolog 2 isoform 1 [Homo
sapiens]
         (1366 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154355002 strawberry notch homolog 2 isoform 1 [Homo sapiens]     2750   0.0  
gi|154355004 strawberry notch homolog 2 isoform 2 [Homo sapiens]     2552   0.0  
gi|33620763 sno, strawberry notch homolog 1 [Homo sapiens]            615   e-176
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    46   2e-04
gi|153792074 proline rich 12 [Homo sapiens]                            44   0.001
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    43   0.002
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    43   0.002
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    43   0.002
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   0.003
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    42   0.003
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          42   0.004
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          42   0.004
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          42   0.004
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   0.005
gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens]         42   0.005
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    42   0.005
gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]       40   0.012
gi|167736355 mucin 4 isoform a [Homo sapiens]                          40   0.015
gi|23238226 CDC42 effector protein 1 [Homo sapiens]                    40   0.015
gi|126090909 engrailed homeobox 1 [Homo sapiens]                       40   0.020
gi|119220564 one cut domain, family member 2 [Homo sapiens]            39   0.034
gi|31657109 zinc finger protein 282 [Homo sapiens]                     39   0.034
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    39   0.045
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    39   0.045
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          39   0.045
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          39   0.045
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          39   0.045
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    38   0.058
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr...    38   0.058
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              38   0.058

>gi|154355002 strawberry notch homolog 2 isoform 1 [Homo sapiens]
          Length = 1366

 Score = 2750 bits (7129), Expect = 0.0
 Identities = 1366/1366 (100%), Positives = 1366/1366 (100%)

Query: 1    MLAVGPAMDRDYPQHEPPPAGSLLYSPPPLQSAMLHCPYWNTFSLPPYPAFSSDSRPFMS 60
            MLAVGPAMDRDYPQHEPPPAGSLLYSPPPLQSAMLHCPYWNTFSLPPYPAFSSDSRPFMS
Sbjct: 1    MLAVGPAMDRDYPQHEPPPAGSLLYSPPPLQSAMLHCPYWNTFSLPPYPAFSSDSRPFMS 60

Query: 61   SASFLGSQPCPDTSYAPVATASSLPPKTCDFAQDSSYFEDFSNISIFSSSVDSLSDIVDT 120
            SASFLGSQPCPDTSYAPVATASSLPPKTCDFAQDSSYFEDFSNISIFSSSVDSLSDIVDT
Sbjct: 61   SASFLGSQPCPDTSYAPVATASSLPPKTCDFAQDSSYFEDFSNISIFSSSVDSLSDIVDT 120

Query: 121  PDFLPADSLNQVSTIWDDNPAPSTHDKLFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQS 180
            PDFLPADSLNQVSTIWDDNPAPSTHDKLFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQS
Sbjct: 121  PDFLPADSLNQVSTIWDDNPAPSTHDKLFQLSRPFAGFEDFLPSHSTPLLVSYQEQSVQS 180

Query: 181  QPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTLAL 240
            QPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTLAL
Sbjct: 181  QPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTLAL 240

Query: 241  PSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGR 300
            PSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGR
Sbjct: 241  PSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGR 300

Query: 301  KKALWFSVSNDLKYDAERDLRDIEATGIAVHALSKIKYGDTTTSEGVLFATYSALIGESQ 360
            KKALWFSVSNDLKYDAERDLRDIEATGIAVHALSKIKYGDTTTSEGVLFATYSALIGESQ
Sbjct: 301  KKALWFSVSNDLKYDAERDLRDIEATGIAVHALSKIKYGDTTTSEGVLFATYSALIGESQ 360

Query: 361  AGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVVYAS 420
            AGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVVYAS
Sbjct: 361  AGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVVYAS 420

Query: 421  ATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQ 480
            ATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQ
Sbjct: 421  ATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQ 480

Query: 481  LSFSGVTFRIEEIPLAPAFECVYNRAALLWAEALNVFQQAADWIGLESRKSLWGQFWSAH 540
            LSFSGVTFRIEEIPLAPAFECVYNRAALLWAEALNVFQQAADWIGLESRKSLWGQFWSAH
Sbjct: 481  LSFSGVTFRIEEIPLAPAFECVYNRAALLWAEALNVFQQAADWIGLESRKSLWGQFWSAH 540

Query: 541  QRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFVSAA 600
            QRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFVSAA
Sbjct: 541  QRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFVSAA 600

Query: 601  EGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESD 660
            EGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESD
Sbjct: 601  EGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESD 660

Query: 661  PGLDSDFNSSPESLVDDDVVIVDAVGLPSDDRGPLCLLQRDPHGPGVLERVERLKQDLLD 720
            PGLDSDFNSSPESLVDDDVVIVDAVGLPSDDRGPLCLLQRDPHGPGVLERVERLKQDLLD
Sbjct: 661  PGLDSDFNSSPESLVDDDVVIVDAVGLPSDDRGPLCLLQRDPHGPGVLERVERLKQDLLD 720

Query: 721  KVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSIDHV 780
            KVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSIDHV
Sbjct: 721  KVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSIDHV 780

Query: 781  NLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGR 840
            NLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGR
Sbjct: 781  NLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGR 840

Query: 841  THRSNQVSAPEYVFLISELAGERRFASIVAKRLESLGALTHGDRRATESRDLSKYNFENK 900
            THRSNQVSAPEYVFLISELAGERRFASIVAKRLESLGALTHGDRRATESRDLSKYNFENK
Sbjct: 841  THRSNQVSAPEYVFLISELAGERRFASIVAKRLESLGALTHGDRRATESRDLSKYNFENK 900

Query: 901  YGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCLDVE 960
            YGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCLDVE
Sbjct: 901  YGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIGGRESRNGCLDVE 960

Query: 961  KDCSITKFLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYE 1020
            KDCSITKFLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYE
Sbjct: 961  KDCSITKFLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYE 1020

Query: 1021 ESQQVFLAPGHPQDGQVVFYKISVDRGLKWEDAFAKSLALTGPYDGFYLSYKVRGNKPSC 1080
            ESQQVFLAPGHPQDGQVVFYKISVDRGLKWEDAFAKSLALTGPYDGFYLSYKVRGNKPSC
Sbjct: 1021 ESQQVFLAPGHPQDGQVVFYKISVDRGLKWEDAFAKSLALTGPYDGFYLSYKVRGNKPSC 1080

Query: 1081 LLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHCSHS 1140
            LLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHCSHS
Sbjct: 1081 LLAEQNRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHCSHS 1140

Query: 1141 AWNRHCRLAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKD 1200
            AWNRHCRLAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKD
Sbjct: 1141 AWNRHCRLAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKD 1200

Query: 1201 RKKQVGIKIPEGCVRRVLQELRLMDADVKRRQAPALGCPAPPAPRPLALPCGPGEVLDLT 1260
            RKKQVGIKIPEGCVRRVLQELRLMDADVKRRQAPALGCPAPPAPRPLALPCGPGEVLDLT
Sbjct: 1201 RKKQVGIKIPEGCVRRVLQELRLMDADVKRRQAPALGCPAPPAPRPLALPCGPGEVLDLT 1260

Query: 1261 YSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLEDML 1320
            YSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLEDML
Sbjct: 1261 YSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAALAHQGCDINFKEVLEDML 1320

Query: 1321 RSLHAGPPSEGALGEGAGAGGAAGGGPERQSVIQFSPPFPGAQAPL 1366
            RSLHAGPPSEGALGEGAGAGGAAGGGPERQSVIQFSPPFPGAQAPL
Sbjct: 1321 RSLHAGPPSEGALGEGAGAGGAAGGGPERQSVIQFSPPFPGAQAPL 1366


>gi|154355004 strawberry notch homolog 2 isoform 2 [Homo sapiens]
          Length = 1309

 Score = 2552 bits (6615), Expect = 0.0
 Identities = 1273/1274 (99%), Positives = 1274/1274 (100%)

Query: 93   QDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDKLFQLS 152
            +DSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDKLFQLS
Sbjct: 36   KDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDKLFQLS 95

Query: 153  RPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKI 212
            RPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKI
Sbjct: 96   RPFAGFEDFLPSHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKI 155

Query: 213  GKQHPDRVVETSTLSSVPPPDITYTLALPSDSGALSALQLEAITYACQQHEVLLPSGQRA 272
            GKQHPDRVVETSTLSSVPPPDITYTLALPSDSGALSALQLEAITYACQQHEVLLPSGQRA
Sbjct: 156  GKQHPDRVVETSTLSSVPPPDITYTLALPSDSGALSALQLEAITYACQQHEVLLPSGQRA 215

Query: 273  GFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATGIAVHA 332
            GFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATGIAVHA
Sbjct: 216  GFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATGIAVHA 275

Query: 333  LSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKA 392
            LSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKA
Sbjct: 276  LSKIKYGDTTTSEGVLFATYSALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKA 335

Query: 393  KNAGSTKMGKAVLDLQNKLPLARVVYASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFL 452
            KNAGSTKMGKAVLDLQNKLPLARVVYASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFL
Sbjct: 336  KNAGSTKMGKAVLDLQNKLPLARVVYASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFL 395

Query: 453  HAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAALLWAE 512
            HAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAALLWAE
Sbjct: 396  HAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAALLWAE 455

Query: 513  ALNVFQQAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVI 572
            ALNVFQQAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVI
Sbjct: 456  ALNVFQQAADWIGLESRKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVI 515

Query: 573  GLQSTGEARTREVLGENDGHLNCFVSAAEGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPR 632
            GLQSTGEARTREVLGENDGHLNCFVSAAEGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPR
Sbjct: 516  GLQSTGEARTREVLGENDGHLNCFVSAAEGVFLSLIQKHFPSTKRKRDRGAGSKRKRRPR 575

Query: 633  GRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGLPSDDR 692
            GRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGLPSDDR
Sbjct: 576  GRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDDDVVIVDAVGLPSDDR 635

Query: 693  GPLCLLQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTG 752
            GPLCLLQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTG
Sbjct: 636  GPLCLLQRDPHGPGVLERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTG 695

Query: 753  RKGRVVSRPDGTVAFESRAEQGLSIDHVNLREKQRFMSGEKLVAIISEASSSGVSLQADR 812
            RKGRVVSRPDGTVAFESRAEQGLSIDHVNLREKQRFMSGEKLVAIISEASSSGVSLQADR
Sbjct: 696  RKGRVVSRPDGTVAFESRAEQGLSIDHVNLREKQRFMSGEKLVAIISEASSSGVSLQADR 755

Query: 813  RVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFASIVAKR 872
            RVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFASIVAKR
Sbjct: 756  RVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFASIVAKR 815

Query: 873  LESLGALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVP 932
            LESLGALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVP
Sbjct: 816  LESLGALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVP 875

Query: 933  TFFRDMKQGLLSVGIGGRESRNGCLDVEKDCSITKFLNRILGLEVHKQNALFQYFSDTFD 992
            TFFRDMKQGLLSVGIGGRESRNGCLDVEKDCSITKFLNRILGLEVHKQNALFQYFSDTFD
Sbjct: 876  TFFRDMKQGLLSVGIGGRESRNGCLDVEKDCSITKFLNRILGLEVHKQNALFQYFSDTFD 935

Query: 993  HLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRGLKWED 1052
            HLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRGLKWED
Sbjct: 936  HLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRGLKWED 995

Query: 1053 AFAKSLALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRR 1112
            AFAKSLALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRR
Sbjct: 996  AFAKSLALTGPYDGFYLSYKVRGNKPSCLLAEQNRGQFFTVYKPNIGRQSQLEALDSLRR 1055

Query: 1113 KFHRVTAEEAKEPWESGYALSLTHCSHSAWNRHCRLAQEGKDCLQGLRLRHHYMLCGALL 1172
            KFHRVTAEEAKEPWESGYALSLTHCSHSAWNRHCRLAQEGKDCLQGLRLRHHYMLCGALL
Sbjct: 1056 KFHRVTAEEAKEPWESGYALSLTHCSHSAWNRHCRLAQEGKDCLQGLRLRHHYMLCGALL 1115

Query: 1173 RVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDADVKRRQ 1232
            RVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDADVKRRQ
Sbjct: 1116 RVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDADVKRRQ 1175

Query: 1233 APALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLG 1292
            APALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLG
Sbjct: 1176 APALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLG 1235

Query: 1293 TPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAAGGGPERQSV 1352
            TPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAAGGGPERQSV
Sbjct: 1236 TPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAAGGGPERQSV 1295

Query: 1353 IQFSPPFPGAQAPL 1366
            IQFSPPFPGAQAPL
Sbjct: 1296 IQFSPPFPGAQAPL 1309


>gi|33620763 sno, strawberry notch homolog 1 [Homo sapiens]
          Length = 1392

 Score =  615 bits (1586), Expect = e-176
 Identities = 329/536 (61%), Positives = 396/536 (73%), Gaps = 40/536 (7%)

Query: 183 EEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTLALPS 242
           +E+DE EEE+ EE+GH ETYA+Y+P K KIG +HPD VVETS+LSSV PPD+ Y  ++  
Sbjct: 222 KEDDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISE 281

Query: 243 ---DSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRG 299
              D+G LSALQLEAITYA QQHE  LP+G RAGFLIGDGAGVGKGRT+AG+I EN+L  
Sbjct: 282 ETIDNGWLSALQLEAITYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLS 341

Query: 300 RKKALWFSVSNDLKYDAERDLRDIEATGIAVHALSKIKYGDTTTS------EGVLFATYS 353
           RK+ALWFSVSNDLKYDAERDLRDI A  I VH+L+K KYG  ++       +GV+FATYS
Sbjct: 342 RKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYS 401

Query: 354 ALIGESQAGGQHRTRLRQILDWCGEAFEGVIVFDECHKAKN---AGS---TKMGKAVLDL 407
           +LIGESQ+GG+++TRL+Q+L WCG+ F+GVIVFDECHKAKN    GS   TK G AVL+L
Sbjct: 402 SLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLEL 461

Query: 408 QNKLPLARVVYASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVA 467
           QNKLP ARVVYASATGASEPRNM YM+RLGIWGEGTPFR F +F+ A+E+RGVGAMEIVA
Sbjct: 462 QNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVA 521

Query: 468 MDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAALLWAEALNVFQQAADWIGLE 527
           MDMK+ GMYIARQLSF+GVTF+IEE+ L+ ++  +YN+A  LW  A   FQQAAD I  E
Sbjct: 522 MDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAE 581

Query: 528 SR--KSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREV 585
            R  KS+WGQFWSAHQRFFKYLCIA+KV+R+V+LAREE+   KCVVIGLQSTGEART E 
Sbjct: 582 QRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEA 641

Query: 586 LGENDGHLNCFVSAAEGVFLSLIQKHFPSTKRKR-----------------DRGAGSKRK 628
           L E  G LN FVS A+GV  SLI+KHFP+  RK+                  R +  K  
Sbjct: 642 LEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSPCKEN 701

Query: 629 RRPRGRGAKAPRLACETAGVIRI----SDDSSTESD--PGLDSDFNSSPESLVDDD 678
           +  + +G +  R A +   V  +    SDDS +ESD     +SD+ SS      DD
Sbjct: 702 KIKKRKGEEITREAKKARKVGGLTGSSSDDSGSESDASDNEESDYESSKNMSSGDD 757



 Score =  568 bits (1465), Expect = e-162
 Identities = 288/522 (55%), Positives = 386/522 (73%), Gaps = 7/522 (1%)

Query: 708  LERVERLKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAF 767
            +ER +++K+DLLDK+ +L  +LP NTLDELID+LGGP+ VAEMTGRKGRVVS  DG++++
Sbjct: 847  VERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISY 906

Query: 768  ESRAEQGLSIDHVNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLEL 827
            ESR+E  + ++ +N+ EKQRFM G+K +AIISEA+SSG+SLQADRR +NQRRRVHMTLEL
Sbjct: 907  ESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLEL 966

Query: 828  PWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFASIVAKRLESLGALTHGDRRAT 887
            PWSADRAIQQFGRTHRSNQV+APEYVFLISELAGE+RFASIVAKRLESLGALTHGDRRAT
Sbjct: 967  PWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRAT 1026

Query: 888  ESRDLSKYNFENKYGTRALHCVLTTILSQTENKVPVPQGYPGGVPTFFRDMKQGLLSVGI 947
            ESRDLS++NF+NKYG  AL  V+ +I++     V  P  YPG    FF+D++QGL+ VG+
Sbjct: 1027 ESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPG---EFFKDVRQGLIGVGL 1083

Query: 948  GGRESRNGCLDVEKDC-SITKFLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDM 1006
               E R+G L ++KD  +I KFLNRILG+EVH+QNALFQYF+DT   +++  K+ G+YDM
Sbjct: 1084 INVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDM 1143

Query: 1007 GILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYKISVDRGLKWEDAFAKSLALTGPYDG 1066
            GILDL  G E++ +   + FL PG+   G V  Y ISV+RG+ WE+A      LTGP DG
Sbjct: 1144 GILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWEEATKIWAELTGPDDG 1203

Query: 1067 FYLSYKVRGNKPSCLLAEQ--NRGQFFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKE 1124
            FYLS ++R NK + +L ++   + + F VY+PN G+Q +LE    L++K+ +V +++A  
Sbjct: 1204 FYLSLQIRNNKKTAILVKEVNPKKKLFLVYRPNTGKQLKLEIYADLKKKYKKVVSDDALM 1263

Query: 1125 PWESGYALSLTHCSHSAWNRHCRLAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMAD 1184
             W   Y  S   C+H+ W  +C+ A  G  C  GLR R +Y+LCG++L VW ++  V+A 
Sbjct: 1264 HWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLAS 1323

Query: 1185 VSSSSY-LQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMD 1225
            VS ++  +QIVRL+T+D ++ VG+ IP  CV  ++  L   D
Sbjct: 1324 VSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSD 1365


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 44/134 (32%), Positives = 50/134 (37%), Gaps = 46/134 (34%)

Query: 1239 PAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFS------FPAPLSLDAGPGVVPLG 1292
            P PP+PR   +P GP        +PPA    PPP  S       PA  ++ AGP   P G
Sbjct: 105  PGPPSPRRPLVPAGP--------APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG 156

Query: 1293 TPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAAGGGPERQSV 1352
             P   A PAALA                    AGP      G G G G   G GP +   
Sbjct: 157  -PAKPAGPAALA------------------ARAGP------GPGPGPGPGPGPGPGK--- 188

Query: 1353 IQFSPPFPGAQAPL 1366
                P  PGA   L
Sbjct: 189  ----PAGPGAAQTL 198



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 43/133 (32%), Positives = 49/133 (36%), Gaps = 32/133 (24%)

Query: 1234 PALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGT 1293
            P +G  APPAP   + P  P        +P A A  PPP    PAP +L   PG  P G 
Sbjct: 242  PFVGAAAPPAPAAPSPPAAP--------APAAPAAAPPP--PPPAPATLARPPG-HPAGP 290

Query: 1294 PDA--QADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAAGGGPERQS 1351
            P A     P A A  G              S  A P    A G  AG  G  G G     
Sbjct: 291  PTAAPAVPPPAAAQNG-------------GSAGAAPAPAPAAGGPAGVSGQPGPGAAA-- 335

Query: 1352 VIQFSPPFPGAQA 1364
                + P PG +A
Sbjct: 336  ----AAPAPGVKA 344



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 45/141 (31%), Positives = 51/141 (36%), Gaps = 44/141 (31%)

Query: 1241 PPAPRPLALPCGPGEVLDL-----TYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPD 1295
            P A  PL  P  PG V+         +PPA A P PP  + PAP    A P   P   P 
Sbjct: 222  PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPP--AAPAP----AAPAAAPPPPPP 275

Query: 1296 AQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEG------ALGEGAGAGGA------A 1343
            A   PA LA                    AGPP+        A  +  G+ GA      A
Sbjct: 276  A---PATLARP--------------PGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPA 318

Query: 1344 GGGPERQSVIQFSPPFPGAQA 1364
             GGP   S      P PGA A
Sbjct: 319  AGGPAGVS----GQPGPGAAA 335



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 47/149 (31%), Positives = 51/149 (34%), Gaps = 28/149 (18%)

Query: 1233 APALGCPAPPAPRPLALPCGPGEVLDLTYSPP--AEAFPPPPHF-------SFPAPLSLD 1283
            APA   P PP P P  L   PG        PP  A A PPP          + PAP    
Sbjct: 265  APA-AAPPPPPPAPATLARPPGH----PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAA 319

Query: 1284 AGPGVVPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAA 1343
             GP  V  G P   A  AA A            E   R + A PP+   L     A  AA
Sbjct: 320  GGPAGVS-GQPGPGAAAAAPAP-------GVKAESPKRVVQAAPPAAQTLAASGPASTAA 371

Query: 1344 GG--GPERQSVI----QFSPPFPGAQAPL 1366
                GP  Q  +       PP PG    L
Sbjct: 372  SMVIGPTMQGALPSPAAVPPPAPGTPTGL 400


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 16/133 (12%)

Query: 1239 PAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQA 1298
            P PP P+P ALP  P  V     SPP    PPPP  + P+P      P   PL  P    
Sbjct: 1473 PPPPPPQP-ALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP-PPPPPPAAAPLAAP--PE 1528

Query: 1299 DPAALAHQGCDINFKEVLEDMLRSLHAGPPSE-----GALGEGAGAGGAAGGGPERQSVI 1353
            +PAA + +  ++          R LH     E     G   E AG  G  G   ER   +
Sbjct: 1529 EPAAPSPEDPEL-------PDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFV 1581

Query: 1354 QFSPPFPGAQAPL 1366
              +   P  +  L
Sbjct: 1582 IRAEDIPSLKLAL 1594



 Score = 30.8 bits (68), Expect = 9.3
 Identities = 20/57 (35%), Positives = 24/57 (42%)

Query: 13   PQHEPPPAGSLLYSPPPLQSAMLHCPYWNTFSLPPYPAFSSDSRPFMSSASFLGSQP 69
            P   PPP    L SPPPL +     P       PP PA  S   P   +A+ L + P
Sbjct: 1471 PPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPP 1527


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
            sapiens]
          Length = 305

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 43/111 (38%), Positives = 50/111 (45%), Gaps = 9/111 (8%)

Query: 1239 PAP-PAPRPLALP-CGPGEVLDLTYSP-PAEA-FPPPPHFSFPAPLSLDAGPGVVPLGTP 1294
            PAP PAP P+A P   P  V  L  +P PA A  P P   + PAP    A P   P   P
Sbjct: 145  PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPA-PAPAPAPAP 203

Query: 1295 DAQADPAALAHQGCDINFK--EVLEDMLRSLHAGPPSEGALGEGAGAGGAA 1343
               A P   A QG +   +  E L D L S  +G P+ G     A A GAA
Sbjct: 204  APDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGT--AAASANGAA 252


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
            sapiens]
          Length = 305

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 43/111 (38%), Positives = 50/111 (45%), Gaps = 9/111 (8%)

Query: 1239 PAP-PAPRPLALP-CGPGEVLDLTYSP-PAEA-FPPPPHFSFPAPLSLDAGPGVVPLGTP 1294
            PAP PAP P+A P   P  V  L  +P PA A  P P   + PAP    A P   P   P
Sbjct: 145  PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPA-PAPAPAPAP 203

Query: 1295 DAQADPAALAHQGCDINFK--EVLEDMLRSLHAGPPSEGALGEGAGAGGAA 1343
               A P   A QG +   +  E L D L S  +G P+ G     A A GAA
Sbjct: 204  APDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGT--AAASANGAA 252


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
            sapiens]
          Length = 316

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 43/111 (38%), Positives = 50/111 (45%), Gaps = 9/111 (8%)

Query: 1239 PAP-PAPRPLALP-CGPGEVLDLTYSP-PAEA-FPPPPHFSFPAPLSLDAGPGVVPLGTP 1294
            PAP PAP P+A P   P  V  L  +P PA A  P P   + PAP    A P   P   P
Sbjct: 156  PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPA-PAPAPAPAP 214

Query: 1295 DAQADPAALAHQGCDINFK--EVLEDMLRSLHAGPPSEGALGEGAGAGGAA 1343
               A P   A QG +   +  E L D L S  +G P+ G     A A GAA
Sbjct: 215  APDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGT--AAASANGAA 263


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 30/73 (41%), Positives = 34/73 (46%), Gaps = 8/73 (10%)

Query: 1239 PAPPAPRPLALPC-----GPGEVLDLTYSPPAEAFPPPPHFSFP--APLSLDAGPGVVPL 1291
            P P AP PLA P       P +      +PP +A P PP  SFP  AP S  A   + PL
Sbjct: 497  PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP-ASFPGQAPFSPSASLPMSPL 555

Query: 1292 GTPDAQADPAALA 1304
             TP  QA P   A
Sbjct: 556  ATPPPQAPPVLAA 568



 Score = 39.3 bits (90), Expect = 0.026
 Identities = 27/69 (39%), Positives = 33/69 (47%), Gaps = 12/69 (17%)

Query: 1236 LGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPD 1295
            L  P+P AP  LA+      +L   +SPP    P PP     AP S  A P V P  TP 
Sbjct: 420  LATPSPQAPNALAV-----HLLQAPFSPP----PSPP---VQAPFSPPASPPVSPSATPP 467

Query: 1296 AQADPAALA 1304
            +QA P+  A
Sbjct: 468  SQAPPSLAA 476



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 8/76 (10%)

Query: 1232 QAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFP---APLSLDAGPGV 1288
            QAP    P+PP   P + P  P   +  + +PP++A   PP  + P    P S  A P +
Sbjct: 437  QAPFSPPPSPPVQAPFSPPASPP--VSPSATPPSQA---PPSLAAPPLQVPPSPPASPPM 491

Query: 1289 VPLGTPDAQADPAALA 1304
             P  TP  QA P   A
Sbjct: 492  SPSATPPPQAPPPLAA 507



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 38/131 (29%), Positives = 45/131 (34%), Gaps = 20/131 (15%)

Query: 1230 RRQAPAL---GCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGP 1286
            R  AP L   G P  P P P A   G  + L   Y          P  + PAP +LD GP
Sbjct: 673  RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG------PESATPAPGALDPGP 726

Query: 1287 GV----------VPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALG-E 1335
                           G        A L           V++ +L        +EGA G  
Sbjct: 727  SPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGS 786

Query: 1336 GAGAGGAAGGG 1346
            G G GGA GGG
Sbjct: 787  GGGPGGAEGGG 797



 Score = 34.3 bits (77), Expect = 0.84
 Identities = 27/67 (40%), Positives = 31/67 (46%), Gaps = 14/67 (20%)

Query: 1239 PAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQA 1298
            P+PP   PLA P  P +      +PPA A PP       AP S  A P + PL TP  QA
Sbjct: 382  PSPPLS-PLATP--PPQ------APPALALPP-----LQAPPSPPASPPLSPLATPSPQA 427

Query: 1299 DPAALAH 1305
              A   H
Sbjct: 428  PNALAVH 434


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 30/73 (41%), Positives = 34/73 (46%), Gaps = 8/73 (10%)

Query: 1239 PAPPAPRPLALPC-----GPGEVLDLTYSPPAEAFPPPPHFSFP--APLSLDAGPGVVPL 1291
            P P AP PLA P       P +      +PP +A P PP  SFP  AP S  A   + PL
Sbjct: 458  PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP-ASFPGQAPFSPSASLPMSPL 516

Query: 1292 GTPDAQADPAALA 1304
             TP  QA P   A
Sbjct: 517  ATPPPQAPPVLAA 529



 Score = 39.3 bits (90), Expect = 0.026
 Identities = 27/69 (39%), Positives = 33/69 (47%), Gaps = 12/69 (17%)

Query: 1236 LGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPD 1295
            L  P+P AP  LA+      +L   +SPP    P PP     AP S  A P V P  TP 
Sbjct: 381  LATPSPQAPNALAV-----HLLQAPFSPP----PSPP---VQAPFSPPASPPVSPSATPP 428

Query: 1296 AQADPAALA 1304
            +QA P+  A
Sbjct: 429  SQAPPSLAA 437



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 8/76 (10%)

Query: 1232 QAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFP---APLSLDAGPGV 1288
            QAP    P+PP   P + P  P   +  + +PP++A   PP  + P    P S  A P +
Sbjct: 398  QAPFSPPPSPPVQAPFSPPASPP--VSPSATPPSQA---PPSLAAPPLQVPPSPPASPPM 452

Query: 1289 VPLGTPDAQADPAALA 1304
             P  TP  QA P   A
Sbjct: 453  SPSATPPPQAPPPLAA 468



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 38/131 (29%), Positives = 45/131 (34%), Gaps = 20/131 (15%)

Query: 1230 RRQAPAL---GCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGP 1286
            R  AP L   G P  P P P A   G  + L   Y          P  + PAP +LD GP
Sbjct: 634  RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG------PESATPAPGALDPGP 687

Query: 1287 GV----------VPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALG-E 1335
                           G        A L           V++ +L        +EGA G  
Sbjct: 688  SPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGS 747

Query: 1336 GAGAGGAAGGG 1346
            G G GGA GGG
Sbjct: 748  GGGPGGAEGGG 758



 Score = 34.3 bits (77), Expect = 0.84
 Identities = 27/67 (40%), Positives = 31/67 (46%), Gaps = 14/67 (20%)

Query: 1239 PAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQA 1298
            P+PP   PLA P  P +      +PPA A PP       AP S  A P + PL TP  QA
Sbjct: 343  PSPPLS-PLATP--PPQ------APPALALPP-----LQAPPSPPASPPLSPLATPSPQA 388

Query: 1299 DPAALAH 1305
              A   H
Sbjct: 389  PNALAVH 395



 Score = 30.8 bits (68), Expect = 9.3
 Identities = 29/93 (31%), Positives = 38/93 (40%), Gaps = 9/93 (9%)

Query: 1218 LQELRLMDADVKRRQA-PALG--------CPAPPAPRPLALPCGPGEVLDLTYSPPAEAF 1268
            LQ LR       R+ A PALG         P+P AP   + P     +     +PP++A 
Sbjct: 268  LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327

Query: 1269 PPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPA 1301
                  +  A  S    P + PL TP  QA PA
Sbjct: 328  TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 360


>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2790

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 37/121 (30%), Positives = 51/121 (42%), Gaps = 22/121 (18%)

Query: 1227 DVKRRQAPALGCPAPP---APRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLD 1283
            +  +R+APA   P       P+P  LP G  E    T  PP    PPPP        S +
Sbjct: 2175 EAPKREAPAFPYPTATLASGPQPF-LPPGK-EATTPTPEPPLPLLPPPPP-------SEE 2225

Query: 1284 AGPGVVPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAA 1343
             GP   P  +P+++A         C ++  ++ +    SL A P S GA G   G GG  
Sbjct: 2226 EGPEEPPKASPESEA---------CSLSAGDLSDSSASSL-AEPESPGAGGTSGGPGGGT 2275

Query: 1344 G 1344
            G
Sbjct: 2276 G 2276


>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 37/121 (30%), Positives = 51/121 (42%), Gaps = 22/121 (18%)

Query: 1227 DVKRRQAPALGCPAPP---APRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLD 1283
            +  +R+APA   P       P+P  LP G  E    T  PP    PPPP        S +
Sbjct: 2091 EAPKREAPAFPYPTATLASGPQPF-LPPGK-EATTPTPEPPLPLLPPPPP-------SEE 2141

Query: 1284 AGPGVVPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAA 1343
             GP   P  +P+++A         C ++  ++ +    SL A P S GA G   G GG  
Sbjct: 2142 EGPEEPPKASPESEA---------CSLSAGDLSDSSASSL-AEPESPGAGGTSGGPGGGT 2191

Query: 1344 G 1344
            G
Sbjct: 2192 G 2192


>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 42.0 bits (97), Expect = 0.004
 Identities = 37/121 (30%), Positives = 51/121 (42%), Gaps = 22/121 (18%)

Query: 1227 DVKRRQAPALGCPAPP---APRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLD 1283
            +  +R+APA   P       P+P  LP G  E    T  PP    PPPP        S +
Sbjct: 2091 EAPKREAPAFPYPTATLASGPQPF-LPPGK-EATTPTPEPPLPLLPPPPP-------SEE 2141

Query: 1284 AGPGVVPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAA 1343
             GP   P  +P+++A         C ++  ++ +    SL A P S GA G   G GG  
Sbjct: 2142 EGPEEPPKASPESEA---------CSLSAGDLSDSSASSL-AEPESPGAGGTSGGPGGGT 2191

Query: 1344 G 1344
            G
Sbjct: 2192 G 2192


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 28/69 (40%), Positives = 35/69 (50%), Gaps = 4/69 (5%)

Query: 1239 PAPPAPRPLA-LPCGPGEVLDLTYSPPAEAFPPPPHFSFP--APLSLDAGPGVVPLGTPD 1295
            P+PPA  P++ L   P +      +PP +A P PP  SFP  AP S  A   + PL TP 
Sbjct: 770  PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA-SFPGQAPFSPSASLPMSPLATPP 828

Query: 1296 AQADPAALA 1304
             QA P   A
Sbjct: 829  PQAPPVLAA 837



 Score = 39.3 bits (90), Expect = 0.026
 Identities = 27/69 (39%), Positives = 33/69 (47%), Gaps = 12/69 (17%)

Query: 1236 LGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPD 1295
            L  P+P AP  LA+      +L   +SPP    P PP     AP S  A P V P  TP 
Sbjct: 645  LATPSPQAPNALAV-----HLLQAPFSPP----PSPP---VQAPFSPPASPPVSPSATPP 692

Query: 1296 AQADPAALA 1304
            +QA P+  A
Sbjct: 693  SQAPPSLAA 701



 Score = 37.4 bits (85), Expect = 0.099
 Identities = 27/90 (30%), Positives = 33/90 (36%), Gaps = 16/90 (17%)

Query: 1232 QAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPP-------------HFSFP- 1277
            QAP      PP   P ++   P +      SPP +  P PP               + P 
Sbjct: 570  QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629

Query: 1278 --APLSLDAGPGVVPLGTPDAQADPAALAH 1305
              AP S  A P + PL TP  QA  A   H
Sbjct: 630  LQAPPSPPASPPLSPLATPSPQAPNALAVH 659



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 8/76 (10%)

Query: 1232 QAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFP---APLSLDAGPGV 1288
            QAP    P+PP   P + P  P   +  + +PP++A   PP  + P    P S  A P +
Sbjct: 662  QAPFSPPPSPPVQAPFSPPASPP--VSPSATPPSQA---PPSLAAPPLQVPPSPPASPPM 716

Query: 1289 VPLGTPDAQADPAALA 1304
             P  TP  QA P   A
Sbjct: 717  SPSATPPPQAPPPLAA 732



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 24/63 (38%), Positives = 28/63 (44%), Gaps = 6/63 (9%)

Query: 1238 CPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQ 1297
            CP    P PL  P  P E      +PP +A   PP  + P PL     P + PL TP  Q
Sbjct: 567  CPLQAPPSPLTTP--PPETPSSIATPPPQA---PPALASP-PLQGLPSPPLSPLATPPPQ 620

Query: 1298 ADP 1300
            A P
Sbjct: 621  APP 623



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 38/131 (29%), Positives = 45/131 (34%), Gaps = 20/131 (15%)

Query: 1230 RRQAPAL---GCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGP 1286
            R  AP L   G P  P P P A   G  + L   Y          P  + PAP +LD GP
Sbjct: 942  RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG------PESATPAPGALDPGP 995

Query: 1287 GV----------VPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALG-E 1335
                           G        A L           V++ +L        +EGA G  
Sbjct: 996  SPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGS 1055

Query: 1336 GAGAGGAAGGG 1346
            G G GGA GGG
Sbjct: 1056 GGGPGGAEGGG 1066



 Score = 32.3 bits (72), Expect = 3.2
 Identities = 28/75 (37%), Positives = 31/75 (41%), Gaps = 17/75 (22%)

Query: 1239 PAPPAPRPLALPCGPGEVLDLTYSPPA------EAFPPP--PHFSFPAPLSLDAGP---- 1286
            P P AP PLA P      L +  SPPA       A PPP  P      PL +   P    
Sbjct: 722  PPPQAPPPLAAP-----PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776

Query: 1287 GVVPLGTPDAQADPA 1301
             + PL  P  QA PA
Sbjct: 777  PMSPLAKPPPQAPPA 791



 Score = 31.6 bits (70), Expect = 5.4
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 27/93 (29%)

Query: 1239 PAPP-----APRPLALPCGPGEVLDLTYSPPAEAFPP----------------PPHFSFP 1277
            P PP      P P  LP  P     L  +PP+ + PP                PP  + P
Sbjct: 316  PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375

Query: 1278 ---APLSLDAGPGV-VP--LGTPDAQADPAALA 1304
               AP SL   P + VP  L +P  QA P+ LA
Sbjct: 376  PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA 408



 Score = 31.2 bits (69), Expect = 7.1
 Identities = 33/98 (33%), Positives = 40/98 (40%), Gaps = 17/98 (17%)

Query: 1218 LQELRLMDADVKRRQA-PALGCPAPPAPRPLALPCGPGEVL------DLTYSPPAEAFPP 1270
            LQ LR       R+ A PALG   P +  PLA P   G         D   +P     PP
Sbjct: 277  LQALRPPQVTPPRKDAAPALG---PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP 333

Query: 1271 PPHFSFPAPL---SLDAGPGV----VPLGTPDAQADPA 1301
             P  + P PL   S  A P +     P  TP +QA P+
Sbjct: 334  SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371



 Score = 31.2 bits (69), Expect = 7.1
 Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 2/63 (3%)

Query: 1239 PAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQA 1298
            PA P   P A P  P  V  L  +PP +  P PP     +PL+         L TP  QA
Sbjct: 742  PASPPMSPSATP--PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799

Query: 1299 DPA 1301
             P+
Sbjct: 800  LPS 802


>gi|108860690 chromosome 16 open reading frame 7 [Homo sapiens]
          Length = 631

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 11/101 (10%)

Query: 1207 IKIPEGCVRRVLQELRL-----MDADVKRRQAPALGCPAPPAPRPLALPCGPGEVLDLTY 1261
            + +P+  + ++L+ L+      +   V R  APA GC  PP P P +    P + L    
Sbjct: 277  LSLPDHPIAQLLRRLQCSVYSALYPAVSRAAAPAPGC-CPPTPNPGSRRLRPSQSLHCML 335

Query: 1262 SPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADPAA 1302
            SPP  +  P P  S P P      PG  P+G+P    D A+
Sbjct: 336  SPPEPSAAPRPQDSPPTP---PLQPG--PVGSPSPLGDTAS 371


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 41.6 bits (96), Expect = 0.005
 Identities = 47/142 (33%), Positives = 53/142 (37%), Gaps = 36/142 (25%)

Query: 1234 PALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFP-----APLSLDAGPGV 1288
            PALGCP PP     +L    G + DL  +PPA A   PP F  P     AP     GP  
Sbjct: 725  PALGCPHPPED-DSSLRAERGSLADLPMAPPASA---PPEFLDPLMGAAAPQYPGRGPPP 780

Query: 1289 VPLGTPD---AQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGAL-GEGAGAGGAAG 1344
             P   P    A ADPAA                        PPS  A  G G  + G   
Sbjct: 781  APPPPPPPPRAPADPAA---------------------SPDPPSAVASPGSGLSSPGPKP 819

Query: 1345 GGPERQSVIQFSP--PFPGAQA 1364
            G    ++   FSP   FPG  A
Sbjct: 820  GDSGYETETPFSPEGAFPGGGA 841


>gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]
          Length = 1439

 Score = 40.4 bits (93), Expect = 0.012
 Identities = 30/79 (37%), Positives = 38/79 (48%), Gaps = 10/79 (12%)

Query: 1220 ELRLMDADVKRRQAPALGCPAPPAPRPLAL-PCGPGEVLDLTYSPPAEA---FPPPPHFS 1275
            ++ ++D D+  R+AP  G P PP P  L L P  P  +LD    PP       PPPP F+
Sbjct: 830  DIDVLDVDLGHREAP--GPPPPPPPTFLGLPPPPPPPLLDSIPPPPVPGNLLVPPPPVFN 887

Query: 1276 FPAPLSLDAGPGVVPLGTP 1294
             P  L    G   VP G P
Sbjct: 888  APQGL----GWSQVPRGQP 902


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 40.0 bits (92), Expect = 0.015
 Identities = 81/359 (22%), Positives = 127/359 (35%), Gaps = 38/359 (10%)

Query: 13   PQHEPPPAGSLLYSPPPLQSAMLHCPYWNTFSLPPYPAFS---SDSRPF----MSSASFL 65
            P   P  A S   +P P+  A    P  +  SLP   A S     + P      SS S  
Sbjct: 1938 PVTSPSSASSGHTTPLPVTDAS-SVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTG 1996

Query: 66   GSQPCPDTSYAPVATASSLPPKTCDFAQDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLP 125
             + P P T  + V+T  + P      +  S+   D + + +  +S  S S   DTP  LP
Sbjct: 1997 HATPLPVTDTSSVSTGQATPLPVTSLSSAST--GDTTPLPVTDTS--SASTGQDTP--LP 2050

Query: 126  ADSLNQVSTIWDDNPAPSTHDKLFQLSRP----FAGFEDFLPSHSTPLLVSYQEQSVQSQ 181
              SL+ VST  D  P P T                        H+T LLV+    SV + 
Sbjct: 2051 VTSLSSVST-GDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVT-DASSVSTG 2108

Query: 182  PEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTLALP 241
                    +  +   G T       PS +  G   P  V +TS++S+     +  T    
Sbjct: 2109 HATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSS 2168

Query: 242  SDSGALSALQLEAITYACQQHEVLLP--------SGQRAGFLIGDGAGVGKGRTVAGVIL 293
            + +G  ++L +   + A   H   LP        +GQ     +   +    G  +  ++ 
Sbjct: 2169 ASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVT 2228

Query: 294  ENHLRGRKKALWFSVSN----------DLKYDAERDLRDIEATGIAVHALSKIKYGDTT 342
            +       +A    V++           L       +    AT + V +LS +  GDTT
Sbjct: 2229 DTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDTT 2287



 Score = 37.7 bits (86), Expect = 0.076
 Identities = 55/225 (24%), Positives = 82/225 (36%), Gaps = 14/225 (6%)

Query: 59   MSSASFLGSQPCPDTSYAPVATASSLP-PKTCDFAQDSSYFEDFSNISIFSSSVDSLSDI 117
            +SSAS   + P P TS +  +T  + P P T     D+S         +  +   S S  
Sbjct: 1318 LSSASTGDTMPLPVTSPSSASTGDTTPLPVT-----DASSVSTGHTTPLHVTDASSASTG 1372

Query: 118  VDTPDFLPADSLNQVSTIWDDNPAPSTHDKLFQLSRP----FAGFEDFLPSHSTPLLVSY 173
              TP  LP  SL+ VST  D  P P T                        H+TPL V+ 
Sbjct: 1373 QATP--LPVTSLSSVST-GDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVT- 1428

Query: 174  QEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPD 233
               SV +            A   GHT        S +  G+     V +TS++S+     
Sbjct: 1429 DASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTP 1488

Query: 234  ITYTLALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGD 278
            +  T    + +G ++ L + + + A   H   LP    +    GD
Sbjct: 1489 LPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGD 1533



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 52/214 (24%), Positives = 75/214 (35%), Gaps = 14/214 (6%)

Query: 69   PCPDTSYAPVATASSLPPKTCDFAQDSSYFEDFSNISIFSSSVDSLSDIVDTPDFLPADS 128
            P  DTS A    A+SLP        D+S         +  +   S S    TP  LP  S
Sbjct: 1122 PVTDTSSASTGHATSLP------VTDTSSVSTGHTTPLHVTDASSASTGQATP--LPVTS 1173

Query: 129  LNQVSTIWDDNPAPSTHDKLFQLSRP----FAGFEDFLPSHSTPLLVSYQEQSVQSQPEE 184
            L+ VST  D  P P T                        H+TPL V+    SV +    
Sbjct: 1174 LSSVST-GDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVT-DASSVSTDHAT 1231

Query: 185  EDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTLALPSDS 244
                    A   GHT        S +  G+     V +TS++S+     +  T    + +
Sbjct: 1232 SLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSAST 1291

Query: 245  GALSALQLEAITYACQQHEVLLPSGQRAGFLIGD 278
            G ++ L + + + A   H   LP    +    GD
Sbjct: 1292 GHVTPLHVTSPSSASTGHATPLPVTSLSSASTGD 1325



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 58/284 (20%), Positives = 97/284 (34%), Gaps = 20/284 (7%)

Query: 60   SSASFLGSQPCPDTSYAPVATASSLP-PKTCDFAQDSSYFEDFSNISIFSSSVDSLSDIV 118
            SSAS   + P P TS + V+T  + P P T   +  + +          S+S    + + 
Sbjct: 2791 SSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLP 2850

Query: 119  DTPDFLPADSLNQVSTIWDDNPAPSTHDKLFQLSRPFAGFEDFLPSHSTPLLVSYQEQSV 178
            DT     +     +  + D + A   H      S P          H+TPL V+    S 
Sbjct: 2851 DTDTSSASTGHATLLPVTDTSSASIGH----ATSLPVTDTSSISTGHATPLHVT-SPSSA 2905

Query: 179  QSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTL 238
             +         +  +   GH        PS +  G   P  V +TS+ S+     +  T 
Sbjct: 2906 STGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTS 2965

Query: 239  ALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLR 298
                 +G  + L + + + A   H   LP        + D +    G+  A  +      
Sbjct: 2966 LSSVSTGDTTPLPVTSPSSASTGHTTPLP--------VTDTSSASTGQATALPVTSTSSA 3017

Query: 299  GRKKALWFSVSNDLKYDAERDLRDIEATGIAVHALSKIKYGDTT 342
                     V++             +AT + V +LS +  GDTT
Sbjct: 3018 STGDTTPLPVTDTSSASTG------QATPLPVTSLSSVSTGDTT 3055



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 52/213 (24%), Positives = 79/213 (37%), Gaps = 12/213 (5%)

Query: 59   MSSASFLGSQPCPDTSYAPVATASSLPPKTCDFAQDSSYFEDFSNISIFSSSVDSLSDIV 118
            +SSAS   + P P T  +  +T  + P    D +  S+  +D + + +  + V S S   
Sbjct: 3750 LSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSAST--DDTTRLPV--TDVSSASTGH 3805

Query: 119  DTPDFLPADSLNQVSTIWDDNPAPSTHDKLFQL----SRPFAGFEDFLPSHSTPLLVSYQ 174
             TP  LP  S +  ST  D  P P T           S P          H+TPL V+  
Sbjct: 3806 ATP--LPVTSTSSAST-GDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVT-D 3861

Query: 175  EQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDI 234
              SV +            +   GH        PS +  G   P  V  TS+ S+     +
Sbjct: 3862 TSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPL 3921

Query: 235  TYTLALPSDSGALSALQLEAITYACQQHEVLLP 267
              T A    +G  + L + + + A +     LP
Sbjct: 3922 PVTNASSLSTGHATPLHVTSPSSASRGDTSTLP 3954



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 51/222 (22%), Positives = 79/222 (35%), Gaps = 16/222 (7%)

Query: 60   SSASFLGSQPCPDTSYAPVATASSLPPKTCDFAQDSSYFEDFSNISIFSSSVDSLSDIVD 119
            SS S   + P P TS + V+T  + P    D + +S+       ++ FSS+    S  + 
Sbjct: 999  SSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLP 1058

Query: 120  TPDF----------LPADSLNQVSTIWDDNPAPSTHDKL----FQLSRPFAGFEDFLPSH 165
              D           LP  SL+  ST  D  P P T           S P          H
Sbjct: 1059 VTDTSSASTGHVTPLPVTSLSSAST-GDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGH 1117

Query: 166  STPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETST 225
            +TPL V+    S  +         +  +   GHT        S +  G+  P  V   S+
Sbjct: 1118 TTPLPVT-DTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSS 1176

Query: 226  LSSVPPPDITYTLALPSDSGALSALQLEAITYACQQHEVLLP 267
            +S+     +  T    + +G  + L +   + A   H   LP
Sbjct: 1177 VSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLP 1218



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 59/239 (24%), Positives = 89/239 (37%), Gaps = 28/239 (11%)

Query: 60   SSASFLGSQPCPDTSYAPVATASSLP-PKTCDFAQDSSYFEDFSNISIFSSSVDSLSDIV 118
            SSAS   + P P TS +  +T  + P P T     D+S        S+  +S+ S+S   
Sbjct: 2231 SSASTGQATPLPVTSLSSASTGDTTPLPVT-----DASSVSTGHATSLPVTSLSSVSTGD 2285

Query: 119  DTPDFLPADSLNQVST-------IWDDNPAPSTHDK---LFQLSRPFAGFEDFLP----- 163
             TP  LP  S +  ST       + D + A + H     +  LS    G    LP     
Sbjct: 2286 TTP--LPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPS 2343

Query: 164  ----SHSTPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDR 219
                 H+TPL V+    SV +            +   GHT        S +  G   P  
Sbjct: 2344 SASTGHATPLHVT-DASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLP 2402

Query: 220  VVETSTLSSVPPPDITYTLALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGD 278
            V +TS+ S+     +  T    + +G  + L +  ++ A   H   LP    +    GD
Sbjct: 2403 VTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGD 2461



 Score = 32.3 bits (72), Expect = 3.2
 Identities = 49/222 (22%), Positives = 79/222 (35%), Gaps = 26/222 (11%)

Query: 60   SSASFLGSQPCPDTSYAPVATASSLP-PKTCDFAQDSSYFEDFSNISIFSSSVDSLSD-- 116
            SSAS   + P P TS + V+T  + P P T   +  + +          S+S    +   
Sbjct: 3079 SSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLP 3138

Query: 117  IVDTPDFLPADSLNQVSTIWDDNPAPSTHDKLFQLSRPFAGFEDFLPSHSTPLLVSYQEQ 176
            + DT      D+ +   T   D  + ST D    L    +        H+TPLLV+    
Sbjct: 3139 VTDTSSAYTGDTTSLPVT---DTSSSSTGDTTPLLVTETSSVST---GHATPLLVT---- 3188

Query: 177  SVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITY 236
                         +  +   GH        PS +  G   P  V +TS++S+     +  
Sbjct: 3189 -------------DASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPV 3235

Query: 237  TLALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGD 278
            T    + +G  + L +  I+ A       LP    +    GD
Sbjct: 3236 TGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGD 3277



 Score = 32.3 bits (72), Expect = 3.2
 Identities = 63/293 (21%), Positives = 101/293 (34%), Gaps = 38/293 (12%)

Query: 60   SSASFLGSQPCPDTSYAPVATASSLPPKTCDFAQDSSYFEDFSNISIFSSS--------- 110
            SSAS   + P P TS + V+T  + P    D +  S+       ++  SS+         
Sbjct: 3431 SSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLP 3490

Query: 111  -VDSLSDIVDTPDFLPADSLNQVSTIWDDNPAPSTHDKLFQLSRPFAGFEDFLPSHSTPL 169
              D+ S        LP  SL+ VST  D  P   T                    H+TPL
Sbjct: 3491 VTDTSSASTGQATPLPVTSLSSVST-GDTTPLLVT------------DASSVSTGHATPL 3537

Query: 170  LVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSV 229
             V+    S  +         +  +   G        +PS S  G   P  V  TS++S+ 
Sbjct: 3538 PVT-DTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTG 3596

Query: 230  PPPDITYTLALPSDSGALSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVA 289
                +  T    + +G ++ L + + + A   H   L        L+ D + V  G    
Sbjct: 3597 HVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPL--------LVTDASSVSTGHATP 3648

Query: 290  GVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATGIAVHALSKIKYGDTT 342
              + +             V++             +AT + V +LS +  GDTT
Sbjct: 3649 LPVTDASSASTGDTTPLPVTDTSSASTG------QATPLPVTSLSSVSTGDTT 3695



 Score = 30.8 bits (68), Expect = 9.3
 Identities = 51/218 (23%), Positives = 81/218 (37%), Gaps = 24/218 (11%)

Query: 60   SSASFLGSQPCPDTSYAPVATASSLPPKTCDFAQDSSYFEDFSNISIFS--SSVDSLSDI 117
            SSAS   + P P TS + V+T  + P    D +  S+       ++I S  S+ D++   
Sbjct: 3671 SSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLP 3730

Query: 118  VDTPDF--------LPADSLNQVSTIWDDNPAPSTHDKLFQLSRPFAGFEDFLPSHSTPL 169
            V +P          LP   L+  ST  D  P P T D     +R           H+TPL
Sbjct: 3731 VTSPSSASTGHATPLPVTGLSSAST-GDTTPLPVT-DTSSASTR-----------HATPL 3777

Query: 170  LVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSV 229
             V+    S  +         +  +   GH         S +  G   P  V +TS++S+ 
Sbjct: 3778 PVT-DTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTG 3836

Query: 230  PPPDITYTLALPSDSGALSALQLEAITYACQQHEVLLP 267
                +  T    + +G  + L +   +     H   LP
Sbjct: 3837 HATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLP 3874


>gi|23238226 CDC42 effector protein 1 [Homo sapiens]
          Length = 391

 Score = 40.0 bits (92), Expect = 0.015
 Identities = 38/123 (30%), Positives = 45/123 (36%), Gaps = 22/123 (17%)

Query: 1232 QAPALGCPAPPA--PRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVV 1289
            +APA   PAP A  P P A P GP             A PP    + PAP +  + P   
Sbjct: 218  EAPAAETPAPAANPPAPTANPTGPA------------ANPPATTANPPAPAANPSAPAAT 265

Query: 1290 PLG------TPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGP--PSEGALGEGAGAGG 1341
            P G       P A + P      G       V E     +  GP  P+  ALG   GAG 
Sbjct: 266  PTGPAANPPAPAASSTPHGHCPNGVTAGLGPVAEVKSSPVGGGPRGPAGPALGRHWGAGW 325

Query: 1342 AAG 1344
              G
Sbjct: 326  DGG 328


>gi|126090909 engrailed homeobox 1 [Homo sapiens]
          Length = 392

 Score = 39.7 bits (91), Expect = 0.020
 Identities = 36/131 (27%), Positives = 46/131 (35%), Gaps = 22/131 (16%)

Query: 1239 PAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQA 1298
            P P  P P A PC P  +    + PP    PPP H + PA                  Q 
Sbjct: 52   PQPAPPSPPAAPCLP-PLAHHPHLPPHPPPPPPQHLAAPAH-----------------QP 93

Query: 1299 DPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAAGGGPER---QSVIQF 1355
             PAA  H+  +     +L          PP +  +   A  G   GG  ER   Q+    
Sbjct: 94   QPAAQLHRTTNFFIDNILRPDFGCKKEQPPPQLLVAAAARGGAGGGGRVERDRGQTAAGR 153

Query: 1356 SPPFP-GAQAP 1365
             P  P G +AP
Sbjct: 154  DPVHPLGTRAP 164



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 37/136 (27%), Positives = 47/136 (34%), Gaps = 22/136 (16%)

Query: 1229 KRRQAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGV 1288
            K ++  ALG  A   P  L+L   PG           ++ P  P    PAP S  A P +
Sbjct: 9    KSQRDSALGAAAAATPGGLSLSLSPGASGSSGSGSDGDSVPVSPQ---PAPPSPPAAPCL 65

Query: 1289 VP------------------LGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSE 1330
             P                  L  P  Q  PAA  H+  +     +L          PP +
Sbjct: 66   PPLAHHPHLPPHPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFGCKKEQPPPQ 125

Query: 1331 GALGEGAGAGGAAGGG 1346
              L   A  GGA GGG
Sbjct: 126  -LLVAAAARGGAGGGG 140


>gi|119220564 one cut domain, family member 2 [Homo sapiens]
          Length = 504

 Score = 38.9 bits (89), Expect = 0.034
 Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 2/52 (3%)

Query: 1306 QGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAAGGGPERQSVIQFSP 1357
            +GC +N  E+  + L +LH GP   G+ G G G GG  GGGP  +  +  SP
Sbjct: 16   EGCAMN-PELTMESLGTLH-GPAGGGSGGGGGGGGGGGGGGPGHEQELLASP 65


>gi|31657109 zinc finger protein 282 [Homo sapiens]
          Length = 671

 Score = 38.9 bits (89), Expect = 0.034
 Identities = 33/121 (27%), Positives = 46/121 (38%), Gaps = 1/121 (0%)

Query: 1228 VKRRQAPALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPG 1287
            +K+ + P    P       L L  GP + L +  +PP     P P    P P  L + P 
Sbjct: 368  IKQEEQPYPWGPRDSMDGELGLDSGPSDSLLMVKNPPPAPPQPQPQPQPPQP-QLQSQPQ 426

Query: 1288 VVPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAAGGGP 1347
               L       +P     +G   +  +VL     S  A P  + + G G G GG  GGG 
Sbjct: 427  PQSLPPIAVAENPGGPPSRGLLDDGFQVLPGERGSGEAPPGGDRSTGGGGGDGGGGGGGA 486

Query: 1348 E 1348
            E
Sbjct: 487  E 487


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 38.5 bits (88), Expect = 0.045
 Identities = 25/68 (36%), Positives = 29/68 (42%), Gaps = 11/68 (16%)

Query: 1234 PALGCPAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGT 1293
            P    P P    P  LP  PG +      PP    PPPP    P P++L   P +VP GT
Sbjct: 817  PTASPPVPAKEEPEELPAAPGPL------PP----PPPPPPPVPGPVTLPP-PQLVPEGT 865

Query: 1294 PDAQADPA 1301
            P     PA
Sbjct: 866  PGGGGPPA 873


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
            sapiens]
          Length = 483

 Score = 38.5 bits (88), Expect = 0.045
 Identities = 49/161 (30%), Positives = 58/161 (36%), Gaps = 37/161 (22%)

Query: 1223 LMDADVKRRQAPALGCPAPPAPRPLALPCG-------PGEVLDLTYSPPAEAFPPPPHFS 1275
            L D  VK + AP L  P  P P PL  PCG       P         PPA   P PP+ S
Sbjct: 243  LSDKAVKPQLAP-LHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYAS 301

Query: 1276 FPAPLSLDAG--PGV---------VPLGTPDAQADPAALAHQGCDINFKEVLEDMLRSLH 1324
                 SL A   PGV         +P  +P  QA P     Q             L +  
Sbjct: 302  CSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQA------------LPAPP 349

Query: 1325 AGPPSEGALGEGAGAGGAAGGGPERQSVIQFSPPFPGAQAP 1365
            A P S+  L +       AGGG          PP P A++P
Sbjct: 350  APPGSQPFLQKKRHGRPGAGGGKLN------PPPAPPARSP 384



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 27/76 (35%), Positives = 32/76 (42%), Gaps = 12/76 (15%)

Query: 1233 APALGC---PAPPAPRPLALPCGPGEVL-DLTYSPPAEAFPPPPHFSFPAPLSLDAGPGV 1288
            AP + C   P PP P P   P  P  VL D    P       PP    P PL     P +
Sbjct: 216  APPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP---IPPPL-----PLL 267

Query: 1289 VPLGTPDAQADPAALA 1304
             P G P  +A+PA+ A
Sbjct: 268  PPCGYPGLKAEPASPA 283



 Score = 30.8 bits (68), Expect = 9.3
 Identities = 34/120 (28%), Positives = 42/120 (35%), Gaps = 17/120 (14%)

Query: 1241 PPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAGPGVVPLGTPDAQADP 1300
            PP P PL  P            PP    PPPP  S P P+S D       L   D +   
Sbjct: 5    PPPPPPLPPP------------PPPLGAPPPPPPSAP-PVSTDTS----SLRRADPKGRS 47

Query: 1301 AALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAAGGGPERQSVIQFSPPFP 1360
            A LA        ++V +   RS      S+G   EG G+    G          F+  FP
Sbjct: 48   ALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFP 107


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 38.5 bits (88), Expect = 0.045
 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 7/76 (9%)

Query: 1232 QAPALGCPAPPAPRPLALP-CGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAG----P 1286
            Q P    P PPAP  LA+P   P     +   P  +A   PPH S P+P S++A     P
Sbjct: 356  QQPPREQPLPPAP--LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP 413

Query: 1287 GVVPLGTPDAQADPAA 1302
             + PL +      P+A
Sbjct: 414  ALKPLSSLSTHHPPSA 429



 Score = 35.4 bits (80), Expect = 0.38
 Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 24/94 (25%)

Query: 1231 RQAPALGCPAPPAPRPLALPCGPGEVLDLTYSP-----PAEAFPPPPHFSFPAPLSLDAG 1285
            +QAPAL    PP+P P   P     +  LT S      P+ A PP      P P SL AG
Sbjct: 247  QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 306

Query: 1286 P-------------------GVVPLGTPDAQADP 1300
            P                   G  PLGT  A A P
Sbjct: 307  PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 38.5 bits (88), Expect = 0.045
 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 7/76 (9%)

Query: 1232 QAPALGCPAPPAPRPLALP-CGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAG----P 1286
            Q P    P PPAP  LA+P   P     +   P  +A   PPH S P+P S++A     P
Sbjct: 910  QQPPREQPLPPAP--LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP 967

Query: 1287 GVVPLGTPDAQADPAA 1302
             + PL +      P+A
Sbjct: 968  ALKPLSSLSTHHPPSA 983



 Score = 35.4 bits (80), Expect = 0.38
 Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 24/94 (25%)

Query: 1231 RQAPALGCPAPPAPRPLALPCGPGEVLDLTYSP-----PAEAFPPPPHFSFPAPLSLDAG 1285
            +QAPAL    PP+P P   P     +  LT S      P+ A PP      P P SL AG
Sbjct: 801  QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 860

Query: 1286 P-------------------GVVPLGTPDAQADP 1300
            P                   G  PLGT  A A P
Sbjct: 861  PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 38.5 bits (88), Expect = 0.045
 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 7/76 (9%)

Query: 1232 QAPALGCPAPPAPRPLALP-CGPGEVLDLTYSPPAEAFPPPPHFSFPAPLSLDAG----P 1286
            Q P    P PPAP  LA+P   P     +   P  +A   PPH S P+P S++A     P
Sbjct: 910  QQPPREQPLPPAP--LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP 967

Query: 1287 GVVPLGTPDAQADPAA 1302
             + PL +      P+A
Sbjct: 968  ALKPLSSLSTHHPPSA 983



 Score = 35.4 bits (80), Expect = 0.38
 Identities = 32/94 (34%), Positives = 36/94 (38%), Gaps = 24/94 (25%)

Query: 1231 RQAPALGCPAPPAPRPLALPCGPGEVLDLTYSP-----PAEAFPPPPHFSFPAPLSLDAG 1285
            +QAPAL    PP+P P   P     +  LT S      P+ A PP      P P SL AG
Sbjct: 801  QQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAG 860

Query: 1286 P-------------------GVVPLGTPDAQADP 1300
            P                   G  PLGT  A A P
Sbjct: 861  PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 894


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
            member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 38.1 bits (87), Expect = 0.058
 Identities = 33/114 (28%), Positives = 39/114 (34%), Gaps = 24/114 (21%)

Query: 1239 PAPPAPRPLALPCGPGEVLDLTYSPPAEAFPPPPHFSFPA----PLSLDAGPGVVPLGTP 1294
            P PP P PL  P  P    D    PP    PPPP ++  A    P      P   P   P
Sbjct: 555  PPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVP 614

Query: 1295 DAQADPAALAHQGCDINFKEVLEDMLRSLHAGPPSEGALGEGAGAGGAAGGGPE 1348
            D+   P A+A +                    PP      E  G  G AGGG +
Sbjct: 615  DSARPPPAVAKR--------------------PPVPPKRQENPGHPGGAGGGEQ 648


>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
            precursor [Homo sapiens]
          Length = 1194

 Score = 38.1 bits (87), Expect = 0.058
 Identities = 56/249 (22%), Positives = 91/249 (36%), Gaps = 34/249 (13%)

Query: 12   YPQHEPPPAGSLLYSPPPLQSAMLHCPYWNTFSLPPYPA-FSSDSRPFMSSASFLGSQPC 70
            Y   E   A  + +SPP   S ++H    +  + PP P+  +++  P      FL     
Sbjct: 955  YNVEEEEDAQPIRFSPPGSPSMVVHRRVPSAATTPPLPSHLTAEETPL-----FLAEPAL 1009

Query: 71   PDTSYAPVATASSLPPKTCDFAQDSSYFEDFSN-ISIFSSSVDSLSDIVDTPDFLPADSL 129
            P     P+      PP      Q  S  +     +S FS+++     ++  P   P + L
Sbjct: 1010 PKGLPPPLQQQQQPPP------QQKSLMDQLQGVVSNFSTAIPDFHAVLAGPGG-PGNGL 1062

Query: 130  NQVSTIWDDNPAPSTHDKLFQLSRPFAGFEDFLP-------SHSTPLLVSYQEQSVQSQP 182
              +       P P  H ++  L     G E   P       S    LL  Y  +  +   
Sbjct: 1063 RSLY----PPPPPPQHLQMLPLQLSTFGEELVSPPADDDDDSERFKLLQEYVYEHEREGN 1118

Query: 183  EEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVP--------PPDI 234
             EEDE EEEE +    ++   D  P+ +       D V   S++ S P        PP++
Sbjct: 1119 TEEDELEEEEEDLQAASKLTPDDSPALTP-PSPFRDSVASGSSVPSSPVSESVLCTPPNV 1177

Query: 235  TYTLALPSD 243
            +Y   +  D
Sbjct: 1178 SYASVILRD 1186



 Score = 31.6 bits (70), Expect = 5.4
 Identities = 20/63 (31%), Positives = 29/63 (46%)

Query: 379 AFEGVIVFDECHKAKNAGSTKMGKAVLDLQNKLPLARVVYASATGASEPRNMIYMSRLGI 438
           A EG+ +        NAG     + +  L+ +LP ARVV     G +    +  M RLG+
Sbjct: 249 AQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGV 308

Query: 439 WGE 441
            GE
Sbjct: 309 VGE 311


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 38.1 bits (87), Expect = 0.058
 Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 174 QEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQ---HPDRVVETSTLSSVP 230
           +E+    + EEEDE EEEE EE    E        KS    +    P+       LSS P
Sbjct: 371 EEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTGEPAPVLSSPP 430

Query: 231 PPDITYTLALPS 242
           P D++  LA PS
Sbjct: 431 PADVSTFLAFPS 442


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,906,228
Number of Sequences: 37866
Number of extensions: 3048863
Number of successful extensions: 20132
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 306
Number of HSP's that attempted gapping in prelim test: 18144
Number of HSP's gapped (non-prelim): 2110
length of query: 1366
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1251
effective length of database: 13,892,928
effective search space: 17380052928
effective search space used: 17380052928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.