Search of human proteins with 154146199

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154146199 sal-like 3 [Homo sapiens]
         (1300 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154146199 sal-like 3 [Homo sapiens]                               2630   0.0  
gi|118442837 sal-like 1 isoform a [Homo sapiens]                     1224   0.0  
gi|189217876 sal-like 1 isoform b [Homo sapiens]                     1161   0.0  
gi|10047144 sal-like 4 [Homo sapiens]                                 595   e-170
gi|49087132 sal-like 2 [Homo sapiens]                                 470   e-132
gi|138175817 zinc finger protein 236 [Homo sapiens]                   131   4e-30
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...   131   5e-30
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...   131   5e-30
gi|148276998 zinc finger protein 628 [Homo sapiens]                   127   9e-29
gi|69885084 p120E4F [Homo sapiens]                                    111   4e-24
gi|22749325 zinc finger protein 48 [Homo sapiens]                     106   1e-22
gi|116256460 zinc finger protein 775 [Homo sapiens]                   104   6e-22
gi|21699088 zinc finger protein 627 [Homo sapiens]                    102   3e-21
gi|51173737 ras responsive element binding protein 1 isoform 1 [...    98   5e-20
gi|4507987 zinc finger protein 136 [Homo sapiens]                      97   8e-20
gi|21687252 zinc finger protein 296 [Homo sapiens]                     96   2e-19
gi|193083160 zinc finger protein 441 [Homo sapiens]                    94   7e-19
gi|47271376 zinc finger protein 615 [Homo sapiens]                     94   7e-19
gi|224548994 zinc finger protein 709 isoform b [Homo sapiens]          94   8e-19
gi|22749235 zinc finger protein 709 isoform a [Homo sapiens]           94   8e-19
gi|40807465 zinc finger protein 341 [Homo sapiens]                     93   1e-18
gi|33438586 zinc finger protein 77 [Homo sapiens]                      92   2e-18
gi|21699060 zinc finger protein 564 [Homo sapiens]                     92   4e-18
gi|153791350 replication initiator 1 isoform 1 [Homo sapiens]          92   4e-18
gi|153792539 replication initiator 1 isoform 1 [Homo sapiens]          92   4e-18
gi|153792647 replication initiator 1 isoform 3 [Homo sapiens]          92   4e-18
gi|153791994 replication initiator 1 isoform 1 [Homo sapiens]          92   4e-18
gi|37622343 zinc finger protein 266 [Homo sapiens]                     91   9e-18
gi|37622349 zinc finger protein 266 [Homo sapiens]                     91   9e-18
gi|13376064 zinc finger protein 408 [Homo sapiens]                     90   1e-17

>gi|154146199 sal-like 3 [Homo sapiens]
          Length = 1300

 Score = 2630 bits (6818), Expect = 0.0
 Identities = 1300/1300 (100%), Positives = 1300/1300 (100%)

Query: 1    MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEF 60
            MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEF
Sbjct: 1    MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEF 60

Query: 61   FKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGA 120
            FKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGA
Sbjct: 61   FKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGA 120

Query: 121  EGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQ 180
            EGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQ
Sbjct: 121  EGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQ 180

Query: 181  FSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRP 240
            FSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRP
Sbjct: 181  FSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRP 240

Query: 241  SLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGAS 300
            SLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGAS
Sbjct: 241  SLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGAS 300

Query: 301  TPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPS 360
            TPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPS
Sbjct: 301  TPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPS 360

Query: 361  PLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKH 420
            PLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKH
Sbjct: 361  PLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKH 420

Query: 421  KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMN 480
            KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMN
Sbjct: 421  KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMN 480

Query: 481  PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY 540
            PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY
Sbjct: 481  PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY 540

Query: 541  ADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVS 600
            ADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVS
Sbjct: 541  ADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVS 600

Query: 601  LPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSE 660
            LPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSE
Sbjct: 601  LPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSE 660

Query: 661  TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720
            TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG
Sbjct: 661  TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720

Query: 721  NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMD 780
            NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMD
Sbjct: 721  NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMD 780

Query: 781  SELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSI 840
            SELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSI
Sbjct: 781  SELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSI 840

Query: 841  AALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESS 900
            AALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESS
Sbjct: 841  AALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESS 900

Query: 901  SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960
            SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA
Sbjct: 901  SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960

Query: 961  PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020
            PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL
Sbjct: 961  PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020

Query: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080
            KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL
Sbjct: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080

Query: 1081 PAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKP 1140
            PAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKP
Sbjct: 1081 PAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKP 1140

Query: 1141 FGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDL 1200
            FGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDL
Sbjct: 1141 FGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDL 1200

Query: 1201 AARAMNVDPSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGSMASGM 1260
            AARAMNVDPSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGSMASGM
Sbjct: 1201 AARAMNVDPSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGSMASGM 1260

Query: 1261 DKARTGSSPPIVSLDKASSETAASRPFTRFIEDNKEIGIN 1300
            DKARTGSSPPIVSLDKASSETAASRPFTRFIEDNKEIGIN
Sbjct: 1261 DKARTGSSPPIVSLDKASSETAASRPFTRFIEDNKEIGIN 1300


>gi|118442837 sal-like 1 isoform a [Homo sapiens]
          Length = 1324

 Score = 1224 bits (3168), Expect = 0.0
 Identities = 706/1377 (51%), Positives = 886/1377 (64%), Gaps = 136/1377 (9%)

Query: 1    MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESR-SGGEETSVCEKCCAE 59
            MSRRKQAKPQH +SD         PE A+      D + G  SR +  ++  VC +CCAE
Sbjct: 1    MSRRKQAKPQHFQSD---------PEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAE 51

Query: 60   FFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSER------------- 106
            FF+ +D L H+++CTK   VLIV+E+ PA PPE F    P  +P E+             
Sbjct: 52   FFELSDLLLHKKNCTKNQLVLIVNEN-PASPPETFSPSPPPDNPDEQMNDTVNKTDQVDC 110

Query: 107  ----------------AESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPA 150
                             E+  A ++G+  + G        +    +  +G   +     +
Sbjct: 111  SDLSEHNGLDREESMEVEAPVANKSGSGTSSGSHSSTAPSSSSSSSSSSGGGGSSSTGTS 170

Query: 151  APAPPTPAYGAPST---------NVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAA 201
            A     P  G  +T         NV +E L STKVAVAQFSQ AR  G SG        A
Sbjct: 171  AITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEARCGGASGG-----KLA 225

Query: 202  VPLILEQLMALQQQQIHQLQLIEQIRSQVALM--QRPPPRPSLSPAAAPSAPGPAP-SQL 258
            VP ++EQL+ALQQQQIHQLQLIEQIR Q+ L+  Q      S SP+         P S L
Sbjct: 226  VPALMEQLLALQQQQIHQLQLIEQIRHQILLLASQNADLPTSSSPSQGTLRTSANPLSTL 285

Query: 259  PGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEP-SAPAAPSAA 317
                +  L+A A  A    S  A+ +  +   P+  P+S +     P+   S+P     A
Sbjct: 286  SSHLSQQLAAAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNTIIPSNSGSSPNMNILA 345

Query: 318  PAPAAPAPAPAPQSAASSQPQ----SASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIF 373
             A   P+      SA +S       S+S+ PA A  SLL  A    +PLLPQ +++  +F
Sbjct: 346  AAVTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPAS---NPLLPQQASANSVF 402

Query: 374  PNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDS 433
            P+PL +I  TA  L+ LSAL + RK KPPNV+ FE K+++++ FFKHKCRFCAKVFGSDS
Sbjct: 403  PSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDS 462

Query: 434  ALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPT 493
            ALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPE+LDN+PT
Sbjct: 463  ALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDNIPT 522

Query: 494  CSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY--ADSPSATPASR 551
             +GIPYGMS+PPEKPVT+WLD+KPVLPT+ TSVGL LPPT+P    +   + P+  P S 
Sbjct: 523  STGIPYGMSIPPEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKTEEPAPIPISH 582

Query: 552  SPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDA 611
            S   P           PG    +SG     ES    LGG P  +AE  +LP +  ++ ++
Sbjct: 583  SATSP-----------PGSVKSDSG---GPESATRNLGGLP-EEAEGSTLPPSGGKSEES 627

Query: 612  PVGAQASAAPTSVD-------------GAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQT 658
              G   ++ PT+               G+ T+  +P LP +SEQFKA+FPFGGLLDS Q 
Sbjct: 628  --GMVTNSVPTASSSVLSSPAADCGPAGSATTFTNPLLPLMSEQFKAKFPFGGLLDSAQA 685

Query: 659  SETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTT 718
            SETSKLQQLVENIDKK TDPN+C+ICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTT
Sbjct: 686  SETSKLQQLVENIDKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTT 745

Query: 719  KGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDA 778
            KGNLKTH+ VHRA PPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTP+P+ + ++
Sbjct: 746  KGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDSYSES 805

Query: 779  MDSEL-AYDDKNAETLSSYDD----DMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSP 833
            M+S+  ++D+KN + L ++ D    D  E S+ D  +  DA+ D          S   SP
Sbjct: 806  MESDTGSFDEKNFDDLDNFSDENMEDCPEGSIPDTPKSADASQD----------SLSSSP 855

Query: 834  -PSVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAG 892
             P  +SSIAALENQMKMI++ ++ Q    LKSVENGS E D L+NDSSS  GD+ES+SAG
Sbjct: 856  LPLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDMESQSAG 915

Query: 893  SPALSESSSS-QALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAP 951
            SPA+SES+SS QALSP+ S  E    KSP +   EE  +  + +E  +  +  P +GGA 
Sbjct: 916  SPAISESTSSMQALSPSNSTQEF--HKSPSI---EEKPQRAVPSEFANGLSPTPVNGGAL 970

Query: 952  GRAG-----IKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFV 1006
                     I +E    +LF  R+RGK  +T C +CGK FAC+SAL+IHYRSHTKERPF+
Sbjct: 971  DLTSSHAEKIIKEDSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFI 1030

Query: 1007 CALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVN 1066
            C +C RG ST GNLKQH+LTH++++LPSQLF+P+  LGP+Q++  + +++  ++IK EVN
Sbjct: 1031 CTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVN 1090

Query: 1067 G--HGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPP-PRRTPKQHNCQSCGKTFS 1123
            G  H       + P       VP+GP  +     +P+L P  PRRTPKQH C +CGKTFS
Sbjct: 1091 GFVHVSPQDSKDTPT----SHVPSGP--LSSSATSPVLLPALPRRTPKQHYCNTCGKTFS 1144

Query: 1124 SASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMA 1183
            S+SALQIHERTHTGEKPF CTICGRAFTTKGNLKVHMGTHMWN+ PARRGRRLSV+ PM 
Sbjct: 1145 SSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMT 1204

Query: 1184 LLGGDALKFSEMFQKDLAARAMNVDP-SFWNQYAAAITNGLAMKNNEISVIQNGGIPQLP 1242
             LGG+ +KF EMFQKDLAAR+ + DP SFWNQYAAA++NGLAMK NEISVIQNGGIP +P
Sbjct: 1205 FLGGNPVKFPEMFQKDLAARSGSGDPSSFWNQYAAALSNGLAMKANEISVIQNGGIPPIP 1264

Query: 1243 VSLGGSALPPLGSMASGMDKARTGS-SPPIVSLDK-ASSETAASRPFTRFIEDNKEI 1297
             SLG     P+  +   +++ +    + P+  L+K ASSE   +  FTRF+ED+KEI
Sbjct: 1265 GSLGSGNSSPVSGLTGNLERLQNSEPNAPLAGLEKMASSENGTNFRFTRFVEDSKEI 1321


>gi|189217876 sal-like 1 isoform b [Homo sapiens]
          Length = 1227

 Score = 1161 bits (3004), Expect = 0.0
 Identities = 659/1244 (52%), Positives = 823/1244 (66%), Gaps = 96/1244 (7%)

Query: 104  SERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPS 163
            S   E+  A ++G+  + G        +    +  +G   +     +A     P  G  +
Sbjct: 27   SMEVEAPVANKSGSGTSSGSHSSTAPSSSSSSSSSSGGGGSSSTGTSAITTSLPQLGDLT 86

Query: 164  T---------NVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQ 214
            T         NV +E L STKVAVAQFSQ AR  G SG        AVP ++EQL+ALQQ
Sbjct: 87   TLGNFSVINSNVIIENLQSTKVAVAQFSQEARCGGASGG-----KLAVPALMEQLLALQQ 141

Query: 215  QQIHQLQLIEQIRSQVALM--QRPPPRPSLSPAAAPSAPGPAP-SQLPGLAALPLSAGAP 271
            QQIHQLQLIEQIR Q+ L+  Q      S SP+         P S L    +  L+A A 
Sbjct: 142  QQIHQLQLIEQIRHQILLLASQNADLPTSSSPSQGTLRTSANPLSTLSSHLSQQLAAAAG 201

Query: 272  AAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEP-SAPAAPSAAPAPAAPAPAPAPQ 330
             A    S  A+ +  +   P+  P+S +     P+   S+P     A A   P+      
Sbjct: 202  LAQSLASQSASISGVKQLPPIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSEKVAS 261

Query: 331  SAASSQPQ----SASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANA 386
            SA +S       S+S+ PA A  SLL  A    +PLLPQ +++  +FP+PL +I  TA  
Sbjct: 262  SAGASHVSNPAVSSSSSPAFAISSLLSPAS---NPLLPQQASANSVFPSPLPNIGTTAED 318

Query: 387  LDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGER 446
            L+ LSAL + RK KPPNV+ FE K+++++ FFKHKCRFCAKVFGSDSALQIHLRSHTGER
Sbjct: 319  LNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGER 378

Query: 447  PFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPE 506
            PFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPE+LDN+PT +GIPYGMS+PPE
Sbjct: 379  PFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDNIPTSTGIPYGMSIPPE 438

Query: 507  KPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY--ADSPSATPASRSPQRPSPASSECA 564
            KPVT+WLD+KPVLPT+ TSVGL LPPT+P    +   + P+  P S S   P        
Sbjct: 439  KPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKTEEPAPIPISHSATSP-------- 490

Query: 565  SLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSV 624
               PG    +SG     ES    LGG P  +AE  +LP +  ++ ++  G   ++ PT+ 
Sbjct: 491  ---PGSVKSDSG---GPESATRNLGGLP-EEAEGSTLPPSGGKSEES--GMVTNSVPTAS 541

Query: 625  D-------------GAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENI 671
                          G+ T+  +P LP +SEQFKA+FPFGGLLDS Q SETSKLQQLVENI
Sbjct: 542  SSVLSSPAADCGPAGSATTFTNPLLPLMSEQFKAKFPFGGLLDSAQASETSKLQQLVENI 601

Query: 672  DKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRA 731
            DKK TDPN+C+ICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTH+ VHRA
Sbjct: 602  DKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRA 661

Query: 732  KPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSEL-AYDDKNA 790
             PPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTP+P+ + ++M+S+  ++D+KN 
Sbjct: 662  MPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGSFDEKNF 721

Query: 791  ETLSSYDD----DMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSP-PSVISSIAALEN 845
            + L ++ D    D  E S+ D  +  DA+ D          S   SP P  +SSIAALEN
Sbjct: 722  DDLDNFSDENMEDCPEGSIPDTPKSADASQD----------SLSSSPLPLEMSSIAALEN 771

Query: 846  QMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSS-QA 904
            QMKMI++ ++ Q    LKSVENGS E D L+NDSSS  GD+ES+SAGSPA+SES+SS QA
Sbjct: 772  QMKMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDMESQSAGSPAISESTSSMQA 831

Query: 905  LSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAG-----IKEE 959
            LSP+ S  E    KSP +   EE  +  + +E  +  +  P +GGA          I +E
Sbjct: 832  LSPSNSTQEF--HKSPSI---EEKPQRAVPSEFANGLSPTPVNGGALDLTSSHAEKIIKE 886

Query: 960  APFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGN 1019
                +LF  R+RGK  +T C +CGK FAC+SAL+IHYRSHTKERPF+C +C RG ST GN
Sbjct: 887  DSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGN 946

Query: 1020 LKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNG--HGKAMALGEG 1077
            LKQH+LTH++++LPSQLF+P+  LGP+Q++  + +++  ++IK EVNG  H       + 
Sbjct: 947  LKQHMLTHQMRDLPSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDT 1006

Query: 1078 PPLPAGVQVPAGPQTVMGPGLAPMLAPP-PRRTPKQHNCQSCGKTFSSASALQIHERTHT 1136
            P       VP+GP  +     +P+L P  PRRTPKQH C +CGKTFSS+SALQIHERTHT
Sbjct: 1007 PT----SHVPSGP--LSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIHERTHT 1060

Query: 1137 GEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMF 1196
            GEKPF CTICGRAFTTKGNLKVHMGTHMWN+ PARRGRRLSV+ PM  LGG+ +KF EMF
Sbjct: 1061 GEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMTFLGGNPVKFPEMF 1120

Query: 1197 QKDLAARAMNVDP-SFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGS 1255
            QKDLAAR+ + DP SFWNQYAAA++NGLAMK NEISVIQNGGIP +P SLG     P+  
Sbjct: 1121 QKDLAARSGSGDPSSFWNQYAAALSNGLAMKANEISVIQNGGIPPIPGSLGSGNSSPVSG 1180

Query: 1256 MASGMDKARTGS-SPPIVSLDK-ASSETAASRPFTRFIEDNKEI 1297
            +   +++ +    + P+  L+K ASSE   +  FTRF+ED+KEI
Sbjct: 1181 LTGNLERLQNSEPNAPLAGLEKMASSENGTNFRFTRFVEDSKEI 1224


>gi|10047144 sal-like 4 [Homo sapiens]
          Length = 1053

 Score =  595 bits (1535), Expect = e-170
 Identities = 428/1075 (39%), Positives = 540/1075 (50%), Gaps = 203/1075 (18%)

Query: 1    MSRRKQAKPQHLKSDE---ELLPPDGAPEHA-----APGEGAEDA-------------DS 39
            MSRRKQAKPQH+ S+E   E  P    PE A     AP  G   A             D 
Sbjct: 1    MSRRKQAKPQHINSEEDQGEQQPQQQTPEFADAAPAAPAAGELGAPVNHPGNDEVASEDE 60

Query: 40   GPESRSGGEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSP 99
                R   EET VCEKCCAEFF  ++FLEH+++CTK PPVLI+++     P EDF     
Sbjct: 61   ATVKRLRREETHVCEKCCAEFFSISEFLEHKKNCTKNPPVLIMNDSEGPVPSEDFSGAVL 120

Query: 100  ASSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTP-- 157
            +  P+     +   E G    + + +P  +    +  E A              PPTP  
Sbjct: 121  SHQPTSPGSKDCHRENGGSSEDMKEKPDAESVVYLKTETA-------------LPPTPQD 167

Query: 158  ----AYG-APSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMAL 212
                A G   +TNVTL+AL  TKVAV Q S  A  A   GA       ++P +LEQ++ L
Sbjct: 168  ISYLAKGKVANTNVTLQALRGTKVAVNQRSADALPAPVPGAN------SIPWVLEQILCL 221

Query: 213  QQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPA 272
            QQQQ+ Q+QL EQIR QV +        S + A      G   SQ    A   LS  A  
Sbjct: 222  QQQQLQQIQLTEQIRIQVNMWASHALHSSGAGADTLKTLGSHMSQQVSAAVALLSQKA-- 279

Query: 273  AAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSA 332
                           G+Q LS                   A   A  P A  P      +
Sbjct: 280  ---------------GSQGLSLD-----------------ALKQAKLPHANIP------S 301

Query: 333  ASSQPQSASTPPALAPGS---LLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDP 389
            A+S       P  L P     L      LPS LLPQ   S V+F +P  ++A   +    
Sbjct: 302  ATSSLSPGLAPFTLKPDGTRVLPNVMSRLPSALLPQAPGS-VLFQSPFSTVALDTS---- 356

Query: 390  LSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFK 449
                 K  KGKPPN+S  + K   E   +KHKC++C+KVFG+DS+LQIHLRSHTGERPF 
Sbjct: 357  -----KKGKGKPPNISAVDVKPKDEAALYKHKCKYCSKVFGTDSSLQIHLRSHTGERPFV 411

Query: 450  CNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLP-PEKP 508
            C++CG+RF+TKGNLKVHF RH    P ++ NP    E+ D V   +GIPY +S+P P   
Sbjct: 412  CSVCGHRFTTKGNLKVHFHRH----PQVKANPQLFAEFQDKVAAGNGIPYALSVPDPIDE 467

Query: 509  VTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSP 568
             +  LDSKPVL  V TSVGL                        PQ          +LS 
Sbjct: 468  PSLSLDSKPVL--VTTSVGL------------------------PQ----------NLSS 491

Query: 569  GLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAP 628
            G N            P+ L GG         SLP      GD   G            +P
Sbjct: 492  GTN------------PKDLTGG---------SLP------GDLQPGP-----------SP 513

Query: 629  TSLGSPGLPAVSEQFKAQFPFGGLLDSMQT----SETSKLQQLVENIDKKMTDPNQCVIC 684
             S G P LP V   + +  P  G      T    SET KLQQLVENIDK  TDPN+C+IC
Sbjct: 514  ESEGGPTLPGVGPNYNS--PRAGGFQGSGTPEPGSETLKLQQLVENIDKATTDPNECLIC 571

Query: 685  HRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPIC 744
            HRVLSCQS+LKMHYRTHTGERPF+CKICGRAF+TKGNLKTH GVHR    ++ QHSCPIC
Sbjct: 572  HRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNTSIKTQHSCPIC 631

Query: 745  QKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSELAYDDKNAETLSSYDDDMDENS 804
            QKKFTNAV+LQQHIRMHMGGQIPNTPLPE   D   SE     +N  T +   DD+ E+ 
Sbjct: 632  QKKFTNAVMLQQHIRMHMGGQIPNTPLPENPCDFTGSEPMTVGENGSTGAICHDDVIESI 691

Query: 805  MEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGLKS 864
              ++   ++A +  +K           SP    + +A+L+   K+  +  + Q+     S
Sbjct: 692  DVEEVSSQEAPSSSSKVPTPLPSIHSASPTLGFAMMASLDAPGKVGPAPFNLQR---QGS 748

Query: 865  VENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSPGLGA 924
             ENGS ESD L+NDSSS +GD E +S  SP + E++S QALSPA S  ES +SKSP  G+
Sbjct: 749  RENGSVESDGLTNDSSSLMGDQEYQSR-SPDILETTSFQALSPANSQAESIKSKSPDAGS 807

Query: 925  PEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAP------------FSLLFLSRERG 972
              E  E   +TE  +  ++ P +        +K E P             + L  ++ R 
Sbjct: 808  KAESSE-NSRTEM-EGRSSLPSTFIRAPPTYVKVEVPGTFVGPSTLSPGMTPLLAAQPRR 865

Query: 973  KCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
            +     C  CGK F+  SAL+IH R+HT E+PFVC +C R  +T GNLK H +TH
Sbjct: 866  QAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTH 920



 Score =  233 bits (595), Expect = 7e-61
 Identities = 130/267 (48%), Positives = 167/267 (62%), Gaps = 17/267 (6%)

Query: 1042 ALGPSQSTPSLISSAAPTM-IKMEVNGHGKAMALGEG---------PPLPAGVQVPA--- 1088
            AL P+ S    I S +P    K E + + +    G           PP    V+VP    
Sbjct: 787  ALSPANSQAESIKSKSPDAGSKAESSENSRTEMEGRSSLPSTFIRAPPTYVKVEVPGTFV 846

Query: 1089 GPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGR 1148
            GP T + PG+ P+LA  PRR  KQH C  CGK FSSASALQIHERTHTGEKPF C ICGR
Sbjct: 847  GPST-LSPGMTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGR 905

Query: 1149 AFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDLAARAMNVD 1208
            AFTTKGNLKVH  TH  NN  ARRGR+L++EN MALLG D  + SE+F K++ A ++NVD
Sbjct: 906  AFTTKGNLKVHYMTHGANNNSARRGRKLAIENTMALLGTDGKRVSEIFPKEILAPSVNVD 965

Query: 1209 PSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGSMASGMDKARTGSS 1268
            P  WNQY + +  GLA+K NEISVIQ+GG+P LPVSLG +++    +  S MD +++G S
Sbjct: 966  PVVWNQYTSMLNGGLAVKTNEISVIQSGGVPTLPVSLGATSVVN-NATVSKMDGSQSGIS 1024

Query: 1269 PPIVSLDKASSETAASRPFTRFIEDNK 1295
              +     ++++      F  F+E+NK
Sbjct: 1025 ADVEK--PSATDGVPKHQFPHFLEENK 1049



 Score =  131 bits (330), Expect = 4e-30
 Identities = 114/368 (30%), Positives = 157/368 (42%), Gaps = 84/368 (22%)

Query: 875  LSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSPGLGA----PEEPQE 930
            +S   S+AV  L S+ AGS  LS  +  QA  P  +   +  S SPGL      P+  + 
Sbjct: 264  MSQQVSAAVA-LLSQKAGSQGLSLDALKQAKLPHANIPSATSSLSPGLAPFTLKPDGTRV 322

Query: 931  IPLKTERPDSPAA--APGSGGAPGRAGIKEEAPFSLLFLS---RERGKCPSTV------- 978
            +P    R  S     APGS        +  ++PFS + L    + +GK P+         
Sbjct: 323  LPNVMSRLPSALLPQAPGS--------VLFQSPFSTVALDTSKKGKGKPPNISAVDVKPK 374

Query: 979  ---------CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRL 1029
                     C  C K F   S+L+IH RSHT ERPFVC++C    +T GNLK H   H  
Sbjct: 375  DEAALYKHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVHFHRHPQ 434

Query: 1030 KELPSQLFDP-----------NFALGPSQ--STPSLISSAAPTMIKMEVNGHGKAMALGE 1076
             +   QLF              +AL        PSL   + P ++   V G  + ++ G 
Sbjct: 435  VKANPQLFAEFQDKVAAGNGIPYALSVPDPIDEPSLSLDSKPVLVTTSV-GLPQNLSSGT 493

Query: 1077 GP------PLPAGVQVPAGPQTVMG---PGLAPMLAPP---------------------- 1105
             P       LP  +Q    P++  G   PG+ P    P                      
Sbjct: 494  NPKDLTGGSLPGDLQPGPSPESEGGPTLPGVGPNYNSPRAGGFQGSGTPEPGSETLKLQQ 553

Query: 1106 -----PRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHM 1160
                  + T   + C  C +  S  S+L++H RTHTGE+PF C ICGRAF+TKGNLK H+
Sbjct: 554  LVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHL 613

Query: 1161 GTHMWNNA 1168
            G H  N +
Sbjct: 614  GVHRTNTS 621



 Score =  125 bits (314), Expect = 3e-28
 Identities = 136/489 (27%), Positives = 198/489 (40%), Gaps = 85/489 (17%)

Query: 312 AAPSAAP-APAAPAPAPAPQSAASSQP-------------QSASTPPALAPGSLLGAAPG 357
           AA +  P A + P P   P  +  S+P              S + P  L  GSL G    
Sbjct: 450 AAGNGIPYALSVPDPIDEPSLSLDSKPVLVTTSVGLPQNLSSGTNPKDLTGGSLPGDLQP 509

Query: 358 LPSPLL---PQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAE 414
            PSP     P     G  + +P       +   +P S  +K ++       V     +  
Sbjct: 510 GPSPESEGGPTLPGVGPNYNSPRAGGFQGSGTPEPGSETLKLQQ------LVENIDKATT 563

Query: 415 DPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK- 473
           DP   ++C  C +V    S+L++H R+HTGERPF+C ICG  FSTKGNLK H   H+   
Sbjct: 564 DP---NECLICHRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNT 620

Query: 474 ---------------------YPHIQMNP------YPVPE----YLDNVPTCSGIPYGMS 502
                                  HI+M+        P+PE    +  + P   G      
Sbjct: 621 SIKTQHSCPICQKKFTNAVMLQQHIRMHMGGQIPNTPLPENPCDFTGSEPMTVGENGSTG 680

Query: 503 LPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAH------GYA-----DSPSAT-PAS 550
                 V   +D + V      S   ++P  +P  H      G+A     D+P    PA 
Sbjct: 681 AICHDDVIESIDVEEVSSQEAPSSSSKVPTPLPSIHSASPTLGFAMMASLDAPGKVGPAP 740

Query: 551 RSPQRPSPASSECASL-SPGLNHVESGVSATAE----SPQSLLGGPPLTKAEPVSLPCTN 605
            + QR    S E  S+ S GL +  S +    E    SP  +L         P +    +
Sbjct: 741 FNLQRQG--SRENGSVESDGLTNDSSSLMGDQEYQSRSPD-ILETTSFQALSPANSQAES 797

Query: 606 ARAGDAPVGAQASAAP---TSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETS 662
            ++     G++A ++    T ++G  +SL S  + A     K + P  G      T    
Sbjct: 798 IKSKSPDAGSKAESSENSRTEMEGR-SSLPSTFIRAPPTYVKVEVP--GTFVGPSTLSPG 854

Query: 663 KLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNL 722
            +  L+    ++    + C  C +  S  SAL++H RTHTGE+PF C ICGRAFTTKGNL
Sbjct: 855 -MTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNL 913

Query: 723 KTHFGVHRA 731
           K H+  H A
Sbjct: 914 KVHYMTHGA 922



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 100/453 (22%), Positives = 149/453 (32%), Gaps = 129/453 (28%)

Query: 708  KCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIP 767
            KCK C + F T  +L+ H   H  + P      C +C  +FT    L+ H   H   +  
Sbjct: 383  KCKYCSKVFGTDSSLQIHLRSHTGERPF----VCSVCGHRFTTKGNLKVHFHRHPQVKA- 437

Query: 768  NTPLPEGFQDAMDSELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAG 827
            N  L   FQD + +             S  D +DE S+  D+          KP+L    
Sbjct: 438  NPQLFAEFQDKVAA-----GNGIPYALSVPDPIDEPSLSLDS----------KPVL---- 478

Query: 828  SCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLE 887
                    V +S+   +N    + S  + + LTG                   S  GDL+
Sbjct: 479  --------VTTSVGLPQN----LSSGTNPKDLTG------------------GSLPGDLQ 508

Query: 888  SRSAGSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGS 947
                               P PS         PG+G               +SP A    
Sbjct: 509  -------------------PGPSPESEGGPTLPGVGP------------NYNSPRAGGFQ 537

Query: 948  GGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVC 1007
            G      G  E      L  + ++       C +C +  +C+S+L++HYR+HT ERPF C
Sbjct: 538  GSGTPEPG-SETLKLQQLVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFQC 596

Query: 1008 ALCRRGCSTMGNLK--------------------------------QHLLTHRLKELPSQ 1035
             +C R  ST GNLK                                QH+  H   ++P+ 
Sbjct: 597  KICGRAFSTKGNLKTHLGVHRTNTSIKTQHSCPICQKKFTNAVMLQQHIRMHMGGQIPNT 656

Query: 1036 LFDPN---------FALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQV 1086
                N           +G + ST ++        I +E     +A +     P P     
Sbjct: 657  PLPENPCDFTGSEPMTVGENGSTGAICHDDVIESIDVEEVSSQEAPSSSSKVPTPLPSIH 716

Query: 1087 PAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCG 1119
             A P   +G  +   L  P +  P   N Q  G
Sbjct: 717  SASP--TLGFAMMASLDAPGKVGPAPFNLQRQG 747



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 13/26 (50%), Positives = 16/26 (61%)

Query: 1112 QHNCQSCGKTFSSASALQIHERTHTG 1137
            QH+C  C K F++A  LQ H R H G
Sbjct: 625  QHSCPICQKKFTNAVMLQQHIRMHMG 650


>gi|49087132 sal-like 2 [Homo sapiens]
          Length = 1007

 Score =  470 bits (1210), Expect = e-132
 Identities = 378/1165 (32%), Positives = 507/1165 (43%), Gaps = 280/1165 (24%)

Query: 1    MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEF 60
            MSRRKQ KPQ L SD E       P  +  G+ +E+           +   VC KCCA+F
Sbjct: 1    MSRRKQRKPQQLISDCE------GPSASENGDASEE-----------DHPQVCAKCCAQF 43

Query: 61   FKWADFLEHQRSCTKLPPVLIV---------HEDAPAPPPEDFPEP----SPASSPSERA 107
                +FL HQ +C+  PPV+++            +  P PE    P    +  S+P +  
Sbjct: 44   TDPTEFLAHQNACSTDPPVMVIIGGQENPNNSSASSEPRPEGHNNPQVMDTEHSNPPDSG 103

Query: 108  ESEAAEEAGAEGAEGEARP-----------------VEKEAEPMDAEPAGDTRAPRPPPA 150
             S   +        GE  P                 +   +  + A P      P PPP 
Sbjct: 104  SSVPTDPTWGPERRGEESPGHFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPP 163

Query: 151  APAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLM 210
             P PP P  G+   N+                                    PLILE+L 
Sbjct: 164  PPPPPPPGVGSGHLNI------------------------------------PLILEELR 187

Query: 211  ALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGA 270
             LQQ+QIHQ+Q+ EQI  QV L+         S      AP  +PS+LPG      +A +
Sbjct: 188  VLQQRQIHQMQMTEQICRQVLLLG--------SLGQTVGAPA-SPSELPGTG----TASS 234

Query: 271  PAAAIAGSGPAAPA----AFEGAQPLSRPESGASTPGG-------PAEPSAPAAPSAAPA 319
                +    P  P         +   S   SGA TP         P     P +      
Sbjct: 235  TKPLLPLFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGR 294

Query: 320  PAAPAPAPAPQSAASSQPQSAS------TPPALAPGSLLGAAPGLPSPLLPQTSASGVIF 373
               P PAP+P    S+    AS      +   L     LGAA GL +     T++ G++ 
Sbjct: 295  SHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEA-----TASPGLLK 349

Query: 374  PNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDS 433
            P                       K     +S  E     E P  +HKCRFCAKVFGSDS
Sbjct: 350  P-----------------------KNGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDS 386

Query: 434  ALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPT 493
            ALQIHLRSHTGERP+KCN+CGNRF+T+GNLKVHF RH+EKYPH+QMNP+PVPE+LD V T
Sbjct: 387  ALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVIT 446

Query: 494  CSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSP 553
             SG+PYGMS+PPEK                                 A+  +ATP     
Sbjct: 447  SSGLPYGMSVPPEK---------------------------------AEEEAATPGGGVE 473

Query: 554  QRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTK------AEPVSLPCTNA- 606
            ++P  AS+   S +  L  + +  + TA +P    G P   K       EP +    N  
Sbjct: 474  RKPLVASTTALSATESLTLLSTS-AGTATAP----GLPAFNKFVLMKAVEPKNKADENTP 528

Query: 607  --RAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKA--QFPFGGLLDSM--QTSE 660
                G A  G   S+  T +  +      P    ++  FK+   FPF  +L+ +    SE
Sbjct: 529  PGSEGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSE 588

Query: 661  TSKLQQLVENIDKK------------------------MTDPNQCVICHRVLSCQSALKM 696
            TSKLQQLVE ID++                         + PNQCVIC RVLSC  AL++
Sbjct: 589  TSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRL 648

Query: 697  HYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQ 756
            HY  H GERPFKCK+CGRAF+T+GNL+ HF  H+A P  R Q+SCPICQKKFTNAV LQQ
Sbjct: 649  HYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQ 708

Query: 757  HIRMHMGGQIPN--TPLPEG---------FQDAMDSELAYDDKNAETLSSYDDDMDENSM 805
            H+RMH+GGQIPN  T LPEG          Q  +    ++  + ++  S  ++  +E   
Sbjct: 709  HVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEE 768

Query: 806  EDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGLKSV 865
            ED+ E +D   +      S AG    S      S+          DS             
Sbjct: 769  EDEEEEEDVTDED-----SLAGRGSESGGEKAISVRG--------DS------------- 802

Query: 866  ENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSP----- 920
            E  SG  + +   +++A    E  S      +E ++ Q+  P P   +S     P     
Sbjct: 803  EEASGAEEEVGTVAAAATAGKEMDS------NEKTTQQSSLPPPPPPDSLDQPQPMEQGS 856

Query: 921  --GLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPS-T 977
               LG  EE      K ER  SPA+A    G      + EE       + +E G+  S  
Sbjct: 857  SGVLGGKEEGG----KPERSSSPASALTPEGEATSVTLVEELSLQEA-MRKEPGESSSRK 911

Query: 978  VCGVCGKPFACKSALEIHYRSHTKERP-FVCALCRRGCSTMGNLKQHLLTHRLKELPSQL 1036
             C VCG+ F  ++ALE H ++H KE P F C  CR+G      LK+H+L   L     Q 
Sbjct: 912  ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHML---LAHHQVQP 968

Query: 1037 FDPNFALGPSQ-STPSLISSAAPTM 1060
            F P+   GP   +  SL+   +P++
Sbjct: 969  FAPH---GPQNIAALSLVPGCSPSI 990



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 32/59 (54%), Positives = 40/59 (67%)

Query: 1105 PPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            P  +   +H C+ C K F S SALQIH R+HTGE+P+ C +CG  FTT+GNLKVH   H
Sbjct: 365  PLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 45/151 (29%), Positives = 65/151 (43%), Gaps = 22/151 (14%)

Query: 1024 LLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAG 1083
            LLT+  K   S  F   + L P  ++PS  S     + K++  G     +   G P    
Sbjct: 562  LLTNHFKSTGSFPFP--YVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAP---- 615

Query: 1084 VQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGC 1143
                    T   P      AP    +   + C  C +  S   AL++H   H GE+PF C
Sbjct: 616  --------TTSAP------APSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKC 661

Query: 1144 TICGRAFTTKGNLKVHMGTHMWNNAPARRGR 1174
             +CGRAF+T+GNL+ H   H    +PA R +
Sbjct: 662  KVCGRAFSTRGNLRAHFVGH--KASPAARAQ 690



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 1081 PAGVQVPAGPQT----VMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHT 1136
            PA    P G  T    V    L   +   P  +  +  C+ CG+ F S +AL+ H++TH 
Sbjct: 875  PASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHP 934

Query: 1137 GEKP-FGCTICGRAFTTKGNLKVHM 1160
             E P F C  C + F  +  LK HM
Sbjct: 935  KEGPLFTCVFCRQGFLERATLKKHM 959



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 67/280 (23%), Positives = 112/280 (40%), Gaps = 38/280 (13%)

Query: 873  DRLSNDSSSAVGDLESRS--AGSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQE 930
            ++   ++++  G +E +   A + ALS + S   LS +        + +PGL  P   + 
Sbjct: 459  EKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTSAGT-----ATAPGL--PAFNKF 511

Query: 931  IPLKTERPDSPA---AAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFA 987
            + +K   P + A     PGS G+   +G+ E +  + + LS+     PS           
Sbjct: 512  VLMKAVEPKNKADENTPPGSEGS-AISGVAESSTATRMQLSKLVTSLPSW---------- 560

Query: 988  CKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQ 1047
              + L  H++S T   PF   L   G S     K   L  ++    +       +  P+ 
Sbjct: 561  --ALLTNHFKS-TGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTT 617

Query: 1048 STPSLISSAAP----TMIKMEVNGHGKAMALG---EGPPLPAGVQVPAGPQTVMGPGLAP 1100
            S P+  SSA+      +I + V    +A+ L     G   P   +V     +  G   A 
Sbjct: 618  SAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAH 677

Query: 1101 ML---APPPRRTPKQHNCQSCGKTFSSASALQIHERTHTG 1137
             +   A P  R   Q++C  C K F++A  LQ H R H G
Sbjct: 678  FVGHKASPAARA--QNSCPICQKKFTNAVTLQQHVRMHLG 715


>gi|138175817 zinc finger protein 236 [Homo sapiens]
          Length = 1845

 Score =  131 bits (330), Expect = 4e-30
 Identities = 136/535 (25%), Positives = 213/535 (39%), Gaps = 78/535 (14%)

Query: 681  CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740
            C  C +     S L  H R HTGERPFKC  CG+AF  KG L+TH   H  + P    H+
Sbjct: 199  CPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKP----HA 254

Query: 741  CPICQKKFTNAVVLQQHI-RMHMGGQIPNTPLPEGFQDAMDSELAYDDKNAETLSSYDDD 799
            C  C   F+    LQ H+ R+H   ++ N P          +E +   K+  +L+++   
Sbjct: 255  CAFCPAAFSQKGNLQSHVQRVH--SEVKNGPTYN------CTECSCVFKSLGSLNTHISK 306

Query: 800  MDENSMEDDAELKDAATDPAKPLLSYAGSCPP--SPPSVISSIAALENQMKMIDSVMSCQ 857
            M     ++      ++T+ A  L +      P     +  +S ++  +   + D +    
Sbjct: 307  MHMGGPQNST----SSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLL 362

Query: 858  QLTGLKSVENGSGESDRLSNDSSSAVG---DLESRSAGSPALSE-------SSSSQALSP 907
            +L+    VE  SG+S +     S  VG   D+  ++  +  LS        + S  A + 
Sbjct: 363  ELSEPAPVE--SGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTS 420

Query: 908  APSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFL 967
            AP       +++P + +    Q  P   E+ +    +P       +  IK+++PF L   
Sbjct: 421  AP------HAQNPDVSSVSNEQTDPTDAEQ-EKEQESPEKLDKKEKKMIKKKSPF-LPGS 472

Query: 968  SRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
             RE       VC  C K F   S L  H R HT E+PF C  C R  +    L  H+ TH
Sbjct: 473  IREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTH 532

Query: 1028 R-LKELPSQLFDPNFALGPSQSTPSLISSAAPTMI------KMEVNGHGKA--------- 1071
              +K    Q    +F+   S      + +            K   +GH K          
Sbjct: 533  TGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHT 592

Query: 1072 -MALGEGPPLPAGVQV-----PAGPQTVMGPGLAP---MLAPPPR--------------R 1108
             +        PA V+V     P     +  P L     ++ P P+               
Sbjct: 593  ELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNE 652

Query: 1109 TPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
              + + C  C + +  +  L+ H R+HTGEKPF C+ CGR F + G LK H+ TH
Sbjct: 653  ADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTH 707



 Score =  119 bits (298), Expect = 2e-26
 Identities = 141/552 (25%), Positives = 209/552 (37%), Gaps = 84/552 (15%)

Query: 678  PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
            P +C  C R       LK H RTHTG + FKC IC  AFTT G+L+ H G+H    P   
Sbjct: 684  PFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRP--- 740

Query: 738  QHSCPICQKKF-----------TNAVVLQQHIRMHM-GGQIPNTPLPEGFQDA---MDSE 782
             + CP CQK F           T+   L Q ++ H     I ++ + +    A   M  E
Sbjct: 741  -YMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVE 799

Query: 783  LAYDD--KNAETLSSYDDDMDENSME-----DDAELKDAATDPAKPL-LSYAGSCPPSPP 834
            +  D+  + AE +++  + M +   +     ++A L     D  +PL     G   P  P
Sbjct: 800  IESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLAD--QPLEADEDGFVAPQDP 857

Query: 835  SVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSS-SAVGDLESRSA-G 892
                    L   +   +     QQ      +  G   +D          V  L+  S   
Sbjct: 858  --------LRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLE 909

Query: 893  SPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPG 952
            S ALS S   Q+L  APS+     + +  L      +E+ L+ +                
Sbjct: 910  SQALSTSFHQQSLLQAPSSDGM--NVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSY 967

Query: 953  RA-----GIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVC 1007
            R      G K+ +       S   G+ P   C +CG+ F     L+ H ++HT  + F C
Sbjct: 968  RCDYCNKGFKKSSHLKQHVRSHT-GEKPYK-CKLCGRGFVSSGVLKSHEKTHTGVKAFSC 1025

Query: 1008 ALCRRGCSTMGNLKQHLLTHR-LKELPSQLFDPNFA--------LGPSQSTPSLISSAAP 1058
            ++C    +T G+L +H+ TH  +K       +  F         +   Q+ PS +S+   
Sbjct: 1026 SVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGE 1085

Query: 1059 T----MIKMEVNGHGKAMALGEGPP----------LPAGVQVPAGPQTVMGPGLAPMLAP 1104
            T    +   E   H    A  +  P                 P    TV    L    A 
Sbjct: 1086 TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAE 1145

Query: 1105 PPRRT------------PKQHNCQS-CGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151
              R +            PK  NC + C K+F   S L  H R HTGEKP+ C  CG++FT
Sbjct: 1146 KDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFT 1205

Query: 1152 TKGNLKVHMGTH 1163
             K  L  H+ TH
Sbjct: 1206 VKSTLDCHVKTH 1217



 Score =  102 bits (255), Expect = 2e-21
 Identities = 105/394 (26%), Positives = 144/394 (36%), Gaps = 74/394 (18%)

Query: 418 FKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH- 476
           F + C  C K F   S L  H+R HTGERPFKC+ CG  F+ KG L+ H  +H  + PH 
Sbjct: 195 FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHA 254

Query: 477 -------------IQMNPYPVPEYLDNVPT-----CSGIPYGMSLPPEKPVTTWLDSKPV 518
                        +Q +   V   + N PT     CS +                 S   
Sbjct: 255 CAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCV---------------FKSLGS 299

Query: 519 LPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHV----- 573
           L T  + + +  P     +   A   +AT     P + + A +  AS  P    V     
Sbjct: 300 LNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQ 359

Query: 574 ---ESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGA-QASAAPTSVDGAPT 629
              E    A  ES QS   G  L+    ++         ++ + +  A+A P     A T
Sbjct: 360 QLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKT 419

Query: 630 SLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKK--------------- 674
           S      P VS     Q            +E  K Q+  E +DKK               
Sbjct: 420 SAPHAQNPDVSSVSNEQ-------TDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGS 472

Query: 675 MTDPN-----QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729
           + + N      C  C +     S L  H R HT E+PFKC  C RAF  K  L  H   H
Sbjct: 473 IREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTH 532

Query: 730 RAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
                 +    C  C K F+ +  L+ HIR+H G
Sbjct: 533 TGIKAFK----CQYCMKSFSTSGSLKVHIRLHTG 562



 Score = 88.2 bits (217), Expect = 5e-17
 Identities = 96/384 (25%), Positives = 146/384 (38%), Gaps = 49/384 (12%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           + E PF   KC  C K F    ALQ H+  HTGE+P  C  C   FS KG    + Q H 
Sbjct: 220 TGERPF---KCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKG----NLQSHV 272

Query: 472 EKYPHIQMNPYPVPEYLDNVPTCSGIPYG--------MSLPPEKPVTTWLDSKPVLPTVP 523
           ++      N    P Y     +C     G        M +   +  T+  ++  VL T  
Sbjct: 273 QRVHSEVKNG---PTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVL-TAT 328

Query: 524 TSVGLQLPPTVPGAHGYADSPSATPASRSPQR-------------PSPASSECASLSPGL 570
               L L  T   A   +  PS+   S   Q+              SP   +  S++ G+
Sbjct: 329 LFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGI 388

Query: 571 NH-------VESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDA--PVGAQASA-- 619
           N          SG+S+   +          T A     P  ++ + +   P  A+     
Sbjct: 389 NQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQ 448

Query: 620 -APTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTD- 677
            +P  +D     +     P +    + +      +      E  K   LV +I     + 
Sbjct: 449 ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C R  + +S L  H +THTG + FKC+ C ++F+T G+LK H  +H    P   
Sbjct: 509 PFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPF-- 566

Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761
             +CP C KKF  +   + HI  H
Sbjct: 567 --ACPHCDKKFRTSGHRKTHIASH 588



 Score = 88.2 bits (217), Expect = 5e-17
 Identities = 127/553 (22%), Positives = 203/553 (36%), Gaps = 105/553 (18%)

Query: 678  PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
            P +C  C +  + +S L  H +THTG++ F C +C  AF+TKG+LK H  +H    P + 
Sbjct: 1194 PYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFK- 1252

Query: 738  QHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLP------EGFQDAMDSELAYDDKNAE 791
               CP C+ +F  +   + H++ H          P      EG Q       +  D N  
Sbjct: 1253 ---CPHCELRFRTSGRRKTHMQFHYKPDPKKARKPMTRSSSEGLQPVNLLNSSSTDPNVF 1309

Query: 792  TL--SSYDDDMDEN--------------SMEDDAELKDAATDPAKPLLS----YAGSCPP 831
             +  S      D+N              S+    +L  + TD +   L        +   
Sbjct: 1310 IMNNSVLTGQFDQNLLQPGLVGQAILPASVSAGGDLTVSLTDGSLATLEGIQLQLAANLV 1369

Query: 832  SPPSVISSI--AALENQMKMID-SVMS---------CQQLTGLKSV--ENGSGESDRLSN 877
             P   IS I  A++ N    ID S++           QQLTG   +  +N S ++   + 
Sbjct: 1370 GPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPGLAPQNSSLQTSDSTV 1429

Query: 878  DSSSAVGDLESRSAGSPA---------LSESSSSQALSPAPSNGESFRSKSPGLGAPE-E 927
             +S  +  +   S              LSE  S    + + +   +    S GL +P   
Sbjct: 1430 PASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGG 1489

Query: 928  PQEIPLKTERPD-SPAAAPGSG-GAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKP 985
            P EI L       S   A  +G  A   +G  +E   ++  L+   G  PST       P
Sbjct: 1490 PHEITLTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTT------P 1543

Query: 986  FACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHL------LTHRLKELPSQLFDP 1039
             +  +    +    +       ++      T G L   L      +T + ++ P+ L DP
Sbjct: 1544 MSPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDP 1603

Query: 1040 NFALGPSQSTPSLI--------SSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQ 1091
            + +      +P +I        +SAA   I  +V G    +A G  P             
Sbjct: 1604 SLSGQGGAGSPQVILVSHTPQSASAACEEIAYQVAGVSGNLAPGNQP------------- 1650

Query: 1092 TVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHER-THTGEKPFGCTICGRAF 1150
                            +  + H C  C + FSSA+ L  H +  H  E+  GC +C +AF
Sbjct: 1651 ---------------EKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAF 1695

Query: 1151 TTKGNLKVHMGTH 1163
                +LK HM TH
Sbjct: 1696 KRATHLKEHMQTH 1708



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 88/378 (23%), Positives = 137/378 (36%), Gaps = 52/378 (13%)

Query: 421  KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMN 480
            KC  C   F +  +L+ H+  H   RP+ C  C   F T  N K           H++ +
Sbjct: 714  KCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCK----------KHMKTH 763

Query: 481  PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY 540
             Y + + L      + I             + +D + +  +    V ++       A   
Sbjct: 764  RYELAQQLQQHQQAASID-----------DSTVDQQSMQASTQMQVEIESDELPQTAEVV 812

Query: 541  ADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAE---SPQSLLGG------- 590
            A +P A      PQ      +E A L   L   +  + A  +   +PQ  L G       
Sbjct: 813  AANPEAM-LDLEPQHV--VGTEEAGLGQQL--ADQPLEADEDGFVAPQDPLRGHVDQFEE 867

Query: 591  --PPLTKAEPVSLP-------CTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSE 641
              P     EP  LP         + +    PV     ++        TS     L     
Sbjct: 868  QSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPS 927

Query: 642  QFKAQFPFGGLLDSMQTSETSKLQ--QLVENIDKKMTDPNQCVICHRVLSCQSALKMHYR 699
                      + +S Q     + Q  Q +E+ + +     +C  C++     S LK H R
Sbjct: 928  SDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVR 987

Query: 700  THTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIR 759
            +HTGE+P+KCK+CGR F + G LK+H   H          SC +C   FT    L +H+ 
Sbjct: 988  SHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF----SCSVCNASFTTNGSLTRHMA 1043

Query: 760  MHMGGQIPNTPL-PEGFQ 776
             HM  +    P   EGF+
Sbjct: 1044 THMSMKPYKCPFCEEGFR 1061



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 46/190 (24%)

Query: 978  VCGVCGKPFACKSALEIHYRSHTKE----RPFVCALCRRGCSTMGNLKQHLLTH-RLKEL 1032
            +C  CG  F  +S L +H   H +E    R   C  C++   T   LK+H+ TH +++  
Sbjct: 122  ICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVS 181

Query: 1033 PSQLFDPNF-ALGPSQSTPSLISS-AAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGP 1090
             ++ ++ N    G + S P    +   P+ +   +  H      GE P            
Sbjct: 182  STRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIH-----TGERP------------ 224

Query: 1091 QTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAF 1150
                                    C  CGK F+   ALQ H   HTGEKP  C  C  AF
Sbjct: 225  ----------------------FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAF 262

Query: 1151 TTKGNLKVHM 1160
            + KGNL+ H+
Sbjct: 263  SQKGNLQSHV 272



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 52/185 (28%), Positives = 73/185 (39%), Gaps = 32/185 (17%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C VC K F+  ++L+ H   H KE   +C+ C    +    L  H+  HR +EL      
Sbjct: 95   CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHR-QELAGTRQH 153

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
               A      T S +     T  K+ V+                     +  + +   G 
Sbjct: 154  ACKACKKEFETSSELKEHMKTHYKIRVSS------------------TRSYNRNIDRSGF 195

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                          ++C  CGKTF   S L  H R HTGE+PF C+ CG+AF  KG L+ 
Sbjct: 196  T-------------YSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQT 242

Query: 1159 HMGTH 1163
            HM  H
Sbjct: 243  HMIKH 247



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 49/183 (26%), Positives = 75/183 (40%), Gaps = 45/183 (24%)

Query: 979  CGVCGKPFACKSALEIHYRS-HTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037
            C  C + F+  + L  H +  H +ER   C +CR+      +LK+H+ TH+         
Sbjct: 1659 CLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQA-------- 1710

Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097
                  GPS      +SS  P + K +        A  +   L    ++  G        
Sbjct: 1711 ------GPS------LSSQKPRVFKCDTC----EKAFAKPSQLERHSRIHTGE------- 1747

Query: 1098 LAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLK 1157
                         +  +C  C K F+  SALQ+H + HTGE+P+ C  C   FT K N+K
Sbjct: 1748 -------------RPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMK 1794

Query: 1158 VHM 1160
            +HM
Sbjct: 1795 LHM 1797



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 28/53 (52%), Positives = 36/53 (67%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            K + C  CGK+F+  S L  H +THTG+K F C +C  AF+TKG+LKVHM  H
Sbjct: 1193 KPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLH 1245



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 84/381 (22%), Positives = 134/381 (35%), Gaps = 70/381 (18%)

Query: 412  SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
            + E PF   KC  C + F S   L+ H+R+HTG + FKC IC   F+T G+L+ H   H 
Sbjct: 680  TGEKPF---KCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHN 736

Query: 472  EKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLP 531
            +  P++              P C           +K   T L+ K  + T    +  QL 
Sbjct: 737  DLRPYM-------------CPYC-----------QKTFKTSLNCKKHMKTHRYELAQQLQ 772

Query: 532  PTVPGA---HGYADSPSATPASR------SPQRPSPASSECASLSPGLNHVESGVSATAE 582
                 A       D  S   +++      S + P  A    A+    L+     V  T E
Sbjct: 773  QHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEE 832

Query: 583  SP-QSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLG--------- 632
            +     L   PL   E   +   +   G      + S A  S + A    G         
Sbjct: 833  AGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQ 892

Query: 633  SPGLPAV----------SEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCV 682
             P  P V          S+     F    LL +  +   +   +L++   ++  D     
Sbjct: 893  QPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELD----- 947

Query: 683  ICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCP 742
                 L  Q +  +        R ++C  C + F    +LK H   H  + P    + C 
Sbjct: 948  -----LQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKP----YKCK 998

Query: 743  ICQKKFTNAVVLQQHIRMHMG 763
            +C + F ++ VL+ H + H G
Sbjct: 999  LCGRGFVSSGVLKSHEKTHTG 1019



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 27/54 (50%), Positives = 37/54 (68%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHM 1164
            K + C+ CG+ F S+  L+ HE+THTG K F C++C  +FTT G+L  HM THM
Sbjct: 993  KPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHM 1046



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 33/104 (31%), Positives = 49/104 (47%), Gaps = 4/104 (3%)

Query: 662  SKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGN 721
            S+L+     +  +    N C  C +     S L  H R HTGE+P+KC  CG++FT K  
Sbjct: 1150 SELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKST 1209

Query: 722  LKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQ 765
            L  H   H  +       SC +C   F+    L+ H+R+H G +
Sbjct: 1210 LDCHVKTHTGQK----LFSCHVCSNAFSTKGSLKVHMRLHTGAK 1249



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 28/64 (43%), Positives = 40/64 (62%), Gaps = 4/64 (6%)

Query: 420  HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKE----KYP 475
            +KC  C K F   S L  H+++HTG++ F C++C N FSTKG+LKVH + H      K P
Sbjct: 1195 YKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCP 1254

Query: 476  HIQM 479
            H ++
Sbjct: 1255 HCEL 1258



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 26/54 (48%), Positives = 34/54 (62%)

Query: 1110 PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            P+   C +C K F+  S L+ H R HTGE+PF CT+C +AF  K  L+VHM  H
Sbjct: 1719 PRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 29/70 (41%), Positives = 39/70 (55%), Gaps = 3/70 (4%)

Query: 400  KPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFST 459
            KP  +       + E PF    C  C K F   SALQ+H++ HTGERP+KC  C   F+ 
Sbjct: 1733 KPSQLERHSRIHTGERPFH---CTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQ 1789

Query: 460  KGNLKVHFQR 469
            K N+K+H +R
Sbjct: 1790 KSNMKLHMKR 1799



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 47/188 (25%), Positives = 78/188 (41%), Gaps = 19/188 (10%)

Query: 290  QPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQ--SAASSQPQSASTPPA-- 345
            QPL   E G   P  P           +PA  +  PA  PQ  +   +  Q    PP   
Sbjct: 842  QPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQ 901

Query: 346  LAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVS 405
            L   S L            ++ A    F    +  A +++ ++  + L++    +  ++ 
Sbjct: 902  LQDSSTL------------ESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQ 949

Query: 406  VFEPKA---SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462
                +    + +     ++C +C K F   S L+ H+RSHTGE+P+KC +CG  F + G 
Sbjct: 950  AQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGV 1009

Query: 463  LKVHFQRH 470
            LK H + H
Sbjct: 1010 LKSHEKTH 1017



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 64/241 (26%), Positives = 91/241 (37%), Gaps = 37/241 (15%)

Query: 524  TSVGLQLP-----PTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVS 578
            TS G Q P     P++ G  G A SP     S +PQ  S A  E A    G+    SG  
Sbjct: 1590 TSQGQQFPALLTDPSLSGQGG-AGSPQVILVSHTPQSASAACEEIAYQVAGV----SGNL 1644

Query: 579  ATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPA 638
            A    P+               L C  A +  A +   +      V G        G P 
Sbjct: 1645 APGNQPEK-------EGRAHQCLECDRAFSSAAVLMHHSK----EVHGRERI---HGCPV 1690

Query: 639  VSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHY 698
              + FK       L + MQT +         ++  +     +C  C +  +  S L+ H 
Sbjct: 1691 CRKAFKRATH---LKEHMQTHQAGP------SLSSQKPRVFKCDTCEKAFAKPSQLERHS 1741

Query: 699  RTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHI 758
            R HTGERPF C +C +AF  K  L+ H   H  + P    + C  C   FT    ++ H+
Sbjct: 1742 RIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP----YKCAYCVMGFTQKSNMKLHM 1797

Query: 759  R 759
            +
Sbjct: 1798 K 1798



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%)

Query: 409  PKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQ 468
            P  S++ P    KC  C K F   S L+ H R HTGERPF C +C   F+ K  L+VH +
Sbjct: 1712 PSLSSQKPRV-FKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMK 1770

Query: 469  RHKEKYPH 476
            +H  + P+
Sbjct: 1771 KHTGERPY 1778



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 1/93 (1%)

Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736
           DP  C +C++  S  ++LK H   H  E    C  CG  FT +  L  H   HR +    
Sbjct: 92  DPT-CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGT 150

Query: 737 VQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNT 769
            QH+C  C+K+F  +  L++H++ H   ++ +T
Sbjct: 151 RQHACKACKKEFETSSELKEHMKTHYKIRVSST 183



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 23/51 (45%), Positives = 33/51 (64%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
           +KC +C + +     L+ H+RSHTGE+PFKC+ CG  F + G LK H + H
Sbjct: 657 YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTH 707



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 50/199 (25%), Positives = 72/199 (36%), Gaps = 33/199 (16%)

Query: 305 PAEPSAPAAPSAAPAPAAPAPAPAPQSAAS-SQPQSASTPPALAPGSLLGAAPGLPSPLL 363
           P + +   A SA+  P++ A +   Q     S+P    +  +  PG  L    G+   +L
Sbjct: 334 PLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDIL 393

Query: 364 PQ-------TSASGVIFPNPLVSIAATA-------------NALDPLSALMKHRKGKPPN 403
            Q       +S      PN       +A                DP  A  +  +  P  
Sbjct: 394 QQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEK 453

Query: 404 VSVFEPKA-SAEDPFFK-----------HKCRFCAKVFGSDSALQIHLRSHTGERPFKCN 451
           +   E K    + PF             H C +CAK F   S L  H+R HT E+PFKC 
Sbjct: 454 LDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCP 513

Query: 452 ICGNRFSTKGNLKVHFQRH 470
            C   F+ K  L  H + H
Sbjct: 514 QCFRAFAVKSTLTAHIKTH 532



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 24/60 (40%), Positives = 32/60 (53%)

Query: 422  CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481
            C  C+  F +  +L++H+R HTG +PFKC  C  RF T G  K H Q H +  P     P
Sbjct: 1225 CHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARKP 1284



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 23/57 (40%), Positives = 33/57 (57%)

Query: 414  EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
            ++P   + C +C K F   S L  H+R HTGE+P+KC+ CG  F+ K  L  H + H
Sbjct: 1161 DEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTH 1217



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 63/299 (21%), Positives = 108/299 (36%), Gaps = 41/299 (13%)

Query: 495  SGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQ 554
            SG P+ ++L       + + ++   PT  +S G   P  +       ++ S +  S +P 
Sbjct: 1487 SGGPHEITLTINNSSLSQVLAQAAGPTATSSSGS--PQEITLTISELNTTSGSLPSTTPM 1544

Query: 555  RPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTN------ARA 608
             PS  S++   +S      ++ V+ T    Q +L G      + V+L  T+      A  
Sbjct: 1545 SPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGG----LDTVTLNITSQGQQFPALL 1600

Query: 609  GDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLV 668
             D  +  Q  A    V     +  S         ++     G L    Q  +  +  Q +
Sbjct: 1601 TDPSLSGQGGAGSPQVILVSHTPQSASAACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCL 1660

Query: 669  ENIDKKMTDP----------------NQCVICHRVLSCQSALKMHYRTHTG--------E 704
            E  D+  +                  + C +C +     + LK H +TH           
Sbjct: 1661 E-CDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKP 1719

Query: 705  RPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
            R FKC  C +AF     L+ H  +H  + P      C +C+K F     LQ H++ H G
Sbjct: 1720 RVFKCDTCEKAFAKPSQLERHSRIHTGERPFH----CTLCEKAFNQKSALQVHMKKHTG 1774



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 24/57 (42%), Positives = 30/57 (52%)

Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736
           +C  C +  S   +LK+H R HTG RPF C  C + F T G+ KTH   H     LR
Sbjct: 539 KCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELR 595



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 6/66 (9%)

Query: 420  HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQM 479
            +KC+ C + F S   L+ H ++HTG + F C++C   F+T G+L  H         H+ M
Sbjct: 995  YKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMA------THMSM 1048

Query: 480  NPYPVP 485
             PY  P
Sbjct: 1049 KPYKCP 1054



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 1/56 (1%)

Query: 1108 RTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            R  K H C  C +TF+    L +H+ TH+GE P  C +C + F+   +LK H+  H
Sbjct: 61   RNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLH 115



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 4/60 (6%)

Query: 704 ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
           +RP+KC  C RA+    +LK H   H  + P +    C  C + F +A VL+ HIR H G
Sbjct: 654 DRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFK----CSQCGRGFVSAGVLKAHIRTHTG 709



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037
            C  C + +     L+ H RSHT E+PF C+ C RG  + G LK H+ TH  LK     + 
Sbjct: 659  CFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLIC 718

Query: 1038 DPNFALGPS 1046
            +  F  G S
Sbjct: 719  NGAFTTGGS 727



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 59/241 (24%), Positives = 90/241 (37%), Gaps = 31/241 (12%)

Query: 541  ADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVS 600
            A  P+AT +S SPQ  +   SE  + S  L                    P  T   P +
Sbjct: 1509 AAGPTATSSSGSPQEITLTISELNTTSGSL--------------------PSTTPMSPSA 1548

Query: 601  LPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFP-FGGLLD----S 655
            +   N     + VG  AS   T  D     + S GL  V+    +Q   F  LL     S
Sbjct: 1549 ISTQNLVMSSSGVGGDASVTLTLAD--TQGMLSGGLDTVTLNITSQGQQFPALLTDPSLS 1606

Query: 656  MQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRA 715
             Q    S    LV +  +  +   +  I ++V      L    +     R  +C  C RA
Sbjct: 1607 GQGGAGSPQVILVSHTPQSASAACE-EIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRA 1665

Query: 716  FTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGF 775
            F++   L  H      +  +   H CP+C+K F  A  L++H++ H  G   ++  P  F
Sbjct: 1666 FSSAAVLMHHSKEVHGRERI---HGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVF 1722

Query: 776  Q 776
            +
Sbjct: 1723 K 1723



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 32/102 (31%), Positives = 39/102 (38%), Gaps = 22/102 (21%)

Query: 681 CVICHRVLSCQSALKMHYRTH----TGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736
           C  C    + QS L +H   H     G R   CK C + F T   LK H   H     +R
Sbjct: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYK---IR 179

Query: 737 VQ---------------HSCPICQKKFTNAVVLQQHIRMHMG 763
           V                +SCP C K F     L +HIR+H G
Sbjct: 180 VSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTG 221



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 4/71 (5%)

Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462
           N+++ +   S EDP     C  C K F   ++L+ H+  H  E    C+ CG+ F+ +  
Sbjct: 80  NLTLHKCTHSGEDP----TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQ 135

Query: 463 LKVHFQRHKEK 473
           L VH + H+++
Sbjct: 136 LAVHMEEHRQE 146



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSH-TGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475
           HKC  C   F  +S  Q H+R H   ++P +C+ C   F+ + NL +H   H  + P
Sbjct: 37  HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP 93



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 21/58 (36%), Positives = 28/58 (48%)

Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARR 1172
            C  C K FS  ++L+ H   H  E+   C+ CG  FT +  L VHM  H    A  R+
Sbjct: 95   CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQ 152



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 52/228 (22%), Positives = 87/228 (38%), Gaps = 13/228 (5%)

Query: 254  APSQLPGLAALPLSAGAPAAAIA-GSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPA 312
            +PS  P    L ++  + +  +A  +GP A ++    Q ++   S  +T  G    + P 
Sbjct: 1485 SPSGGPHEITLTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPM 1544

Query: 313  APSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPG----SLLGAAPGLPSPLL---PQ 365
            +PSA         +      AS     A T   L+ G    +L   + G   P L   P 
Sbjct: 1545 SPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDPS 1604

Query: 366  TSASGVIFPNPLVSIAATANALDPLSALMKHR-KGKPPNVSVFEPKASAEDPFFKHKCRF 424
             S  G      ++ ++ T  +       + ++  G   N++   P    E     H+C  
Sbjct: 1605 LSGQGGAGSPQVILVSHTPQSASAACEEIAYQVAGVSGNLA---PGNQPEKEGRAHQCLE 1661

Query: 425  CAKVFGSDSALQIHLRS-HTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
            C + F S + L  H +  H  ER   C +C   F    +LK H Q H+
Sbjct: 1662 CDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQ 1709



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 1/57 (1%)

Query: 1108 RTPKQHNCQSCGKTFSSASALQIHERTH-TGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            + P  H C+ C  +F   S  Q H R H   +KP  C  C + F  + NL +H  TH
Sbjct: 32   QVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTH 88



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 16/50 (32%), Positives = 26/50 (52%)

Query: 422  CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
            C  C   F ++ +L  H+ +H   +P+KC  C   F T  + K H +RH+
Sbjct: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ 1074



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 19/54 (35%), Positives = 26/54 (48%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKEL 1032
            C  C K F   S L  H R HT E+P+ C  C +  +    L  H+ TH  ++L
Sbjct: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKL 1222



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 2/74 (2%)

Query: 958  EEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTM 1017
            +E+ F       ER   P   C  C + F  +  L +H  +H+ E P  C +C +  S +
Sbjct: 48   KESQFQRHMRDHERNDKPHR-CDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRV 105

Query: 1018 GNLKQHLLTHRLKE 1031
             +LK H++ H  +E
Sbjct: 106  ASLKAHIMLHEKEE 119



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 17/53 (32%), Positives = 20/53 (37%), Gaps = 4/53 (7%)

Query: 422 CRFCAKVFGSDSALQIHLRSH----TGERPFKCNICGNRFSTKGNLKVHFQRH 470
           C  C   F   S L +H+  H     G R   C  C   F T   LK H + H
Sbjct: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH 175



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 4/58 (6%)

Query: 709  CKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQI 766
            C  C ++F    +L  H  +H  + P    + C  C K FT    L  H++ H G ++
Sbjct: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKP----YKCDECGKSFTVKSTLDCHVKTHTGQKL 1222



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 20/78 (25%), Positives = 29/78 (37%), Gaps = 24/78 (30%)

Query: 708 KCKICGRAFTTKGNLKTHFGVH-RAKPPLRVQH-----------------------SCPI 743
           KC+IC  +F  +   + H   H R   P R                          +CP+
Sbjct: 38  KCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDPTCPV 97

Query: 744 CQKKFTNAVVLQQHIRMH 761
           C KKF+    L+ HI +H
Sbjct: 98  CNKKFSRVASLKAHIMLH 115


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
            sapiens]
          Length = 1059

 Score =  131 bits (329), Expect = 5e-30
 Identities = 236/1025 (23%), Positives = 329/1025 (32%), Gaps = 236/1025 (23%)

Query: 184  GARAAGGSGAGG--GVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQ---RPPP 238
            GA   G SG GG  GV   + P   + L  L  Q+   ++L  +    VA +     PPP
Sbjct: 9    GAGGGGSSGIGGEDGVHFQSYPF--DFLEFLNHQRFEPMELYGEHAKAVAALPCAPGPPP 66

Query: 239  RPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESG 298
            +P       P  P P     P     P S   P A +  S  ++ ++   +   S   S 
Sbjct: 67   QP-------PPQPPPPQYDYP-----PQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSS 114

Query: 299  ASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAA---SSQPQSASTPPALAPGSLLGAA 355
            +S+     +P  P A  A P P   A  P PQ      S             P S  G  
Sbjct: 115  SSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVT 174

Query: 356  PGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAED 415
            PGL +P                      A A  PL A  +   G PP  +  +P    + 
Sbjct: 175  PGLGAP----------------------AGAPGPLPAPSQTPPG-PPAAAACDPTKDDKG 211

Query: 416  PFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475
             F + K                    +  ER F C +C   F    +L  H   H  + P
Sbjct: 212  YFRRLK--------------------YLMERRFPCGVCQKSFKQSSHLVQHMLVHSGERP 251

Query: 476  HIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVP 535
            +                       G+       V++ +  +     VP + G    P  P
Sbjct: 252  Y---------------------ECGVCGRTYNHVSSLIRHRRCHKDVPPAAG---GPPQP 287

Query: 536  GAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTK 595
            G H     P   PA        PA+S                +ATA +P ++  GPP T 
Sbjct: 288  GPHL---PPLGLPA--------PAAS----------------AATAAAPSTVSSGPPATP 320

Query: 596  AEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDS 655
              P            AP  A  SAAP  V   P + G                 GG    
Sbjct: 321  VAP------------AP-SADGSAAPAGVGVPPPATG-----------------GG---- 346

Query: 656  MQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRA 715
                                  P  C +C +V    S L  H   HTGE+PF C +C ++
Sbjct: 347  --------------------DGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKS 386

Query: 716  FTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMH----MGGQIPNTP- 770
            F  + +LK H   H A     ++  C IC K F +A  L +H   H     GG  P  P 
Sbjct: 387  FNRRESLKRHVKTHSAD---LLRLPCGICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPC 443

Query: 771  -LPEGFQDAMDSELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGS- 828
             L      A  S L +   +A   ++ +   D            AA+ P  P     G  
Sbjct: 444  DLCGKSYSAPQSLLRHKAAHAPPAAAAEAPKD-----------GAASAPQPPPTFPPGPY 492

Query: 829  -CPPSPPSVISSIAALENQMKMIDSV----MSCQQLT---GLKSVENGSGESDRLSNDSS 880
              PP PP+  S  AA      +  +V    +    L       S   GSG S        
Sbjct: 493  LLPPDPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCC 552

Query: 881  SAVGDLESRSAGSPALSESSSSQALSPAPSNGESFR-----SKSPGLGAPEEPQEIPL-- 933
               G    R           + +     P  G+ FR     SK   +   E P +  L  
Sbjct: 553  GICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCELCG 612

Query: 934  -------------KTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCG 980
                         +  R   P A  G+ G P   G            S       S  C 
Sbjct: 613  KVFGYPQSLTRHRQVHRLQLPCALAGAAGLPSTQGTPGACGPGASGTSAGPTDGLSYACS 672

Query: 981  VCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPN 1040
             CG+ F     +  H   H  E+P+ C  C +    + NL  H L H  +  P +L  P 
Sbjct: 673  DCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLVH--QAAPERLLPP- 729

Query: 1041 FALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQ--VPAGPQTVMGPGL 1098
                P    P   SS         V  +G A  +G      AGV     AG   V G G 
Sbjct: 730  ---APGGLQPPDGSSGTDA---ASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAVAGAGG 783

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                       P++ +C +CG++F     L  H+  H   +  GC +CG++F    +L +
Sbjct: 784  GASSG------PERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLL 837

Query: 1159 HMGTH 1163
            H  +H
Sbjct: 838  HRRSH 842



 Score =  111 bits (278), Expect = 4e-24
 Identities = 168/753 (22%), Positives = 238/753 (31%), Gaps = 184/753 (24%)

Query: 37  ADSGPESRSGGEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDA---------P 87
           A  G  S  GGE+    +    +F    +FL HQR      P+ +  E A         P
Sbjct: 10  AGGGGSSGIGGEDGVHFQSYPFDFL---EFLNHQR----FEPMELYGEHAKAVAALPCAP 62

Query: 88  APPPEDFPEPSPA--SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAP 145
            PPP+  P+P P     P +      AE   +  +   +      +    +  +   + P
Sbjct: 63  GPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKP 122

Query: 146 RP--PPAAPAPPTPAYGA--PSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAA 201
            P  PPA  APP P + A  P+    +  L   +       +G  A+G     G  A A 
Sbjct: 123 DPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVTPGLGAPAG 182

Query: 202 VPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPS----- 256
            P                                P P PS +P   P+A    P+     
Sbjct: 183 AP-------------------------------GPLPAPSQTPPGPPAAAACDPTKDDKG 211

Query: 257 ---QLPGLAALPLSAGAPAAAIAGSGPAAP--AAFEGAQPLSRPESGAS----------- 300
              +L  L       G    +   S           G +P      G +           
Sbjct: 212 YFRRLKYLMERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHR 271

Query: 301 --------TPGGPAEPSAPAAPSAAPAPAA-PAPAPAPQSAASSQPQSASTPPALAPGSL 351
                     GGP +P     P   PAPAA  A A AP + +S  P +   P   A GS 
Sbjct: 272 RCHKDVPPAAGGPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSA 331

Query: 352 LGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKA 411
             A  G+P P      A+G                                         
Sbjct: 332 APAGVGVPPP------ATG----------------------------------------- 344

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
             + PF    C  C KVF   S L  H   HTGE+PF C++C   F+ + +LK H + H 
Sbjct: 345 GGDGPF---ACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHS 401

Query: 472 EKYPHIQMN---------PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTV 522
                +             Y +     +    +G P                 +PV P  
Sbjct: 402 ADLLRLPCGICGKAFRDASYLLKHQAAHAGAGAGGP-----------------RPVYPCD 444

Query: 523 PTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAE 582
                   P ++   H  A +P A  A       + A     +  PG             
Sbjct: 445 LCGKSYSAPQSLL-RHKAAHAPPAAAAEAPKDGAASAPQPPPTFPPG------------- 490

Query: 583 SPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTS-LGSPGLPAVSE 641
            P  L   PP T +E  +        G  PV     A P  + GA TS  G  G     +
Sbjct: 491 -PYLLPPDPPTTDSEKAAAAAAAVVYGAVPV-PLLGAHPLLLGGAGTSGAGGSGASVPGK 548

Query: 642 QFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTH 701
            F       G        ET K  + +   +K    P+QC +C +       L  H+  H
Sbjct: 549 TFCCGICGRG----FGRRETLKRHERIHTGEK----PHQCPVCGKRFRESFHLSKHHVVH 600

Query: 702 TGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734
           T ERP+KC++CG+ F    +L  H  VHR + P
Sbjct: 601 TRERPYKCELCGKVFGYPQSLTRHRQVHRLQLP 633



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 164/674 (24%), Positives = 225/674 (33%), Gaps = 122/674 (18%)

Query: 147 PPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGA-----GGGVAAAA 201
           PP   PAP   A  A + +       +T VA A  + G+ A  G G      GGG    A
Sbjct: 292 PPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFA 351

Query: 202 VPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGL 261
            PL  +     +   +HQ Q+I       +         S S     S      +    L
Sbjct: 352 CPLCWKVFK--KPSHLHQHQIIHTGEKPFSCSVC-----SKSFNRRESLKRHVKTHSADL 404

Query: 262 AALPLSAGAPA-----------AAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSA 310
             LP      A           AA AG+G   P       P        S P       A
Sbjct: 405 LRLPCGICGKAFRDASYLLKHQAAHAGAGAGGPRP---VYPCDLCGKSYSAPQSLLRHKA 461

Query: 311 PAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASG 370
             AP     PAA A AP   +A++ QP     PP   PG      P L  P  P T +  
Sbjct: 462 AHAP-----PAAAAEAPKDGAASAPQP-----PPTFPPG------PYLLPPDPPTTDSE- 504

Query: 371 VIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFG 430
                   + AA      P+  L  H        +     + A  P     C  C + FG
Sbjct: 505 ----KAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCCGICGRGFG 560

Query: 431 SDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDN 490
               L+ H R HTGE+P +C +CG RF    +L  H   H  + P+              
Sbjct: 561 RRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPY-------------K 607

Query: 491 VPTCSGI-PYGMSLPPEKPVTTWLDSKPVLP-TVPTSVGLQLPPTVPGAHGYADSPSATP 548
              C  +  Y  SL   + V      +  LP  +  + GL      PGA G    P A+ 
Sbjct: 608 CELCGKVFGYPQSLTRHRQV-----HRLQLPCALAGAAGLPSTQGTPGACG----PGASG 658

Query: 549 ASRSPQRP-SPASSECASLSPGLNHVES-----------GVSATAES------------- 583
            S  P    S A S+C    P L HV S           G  A  ++             
Sbjct: 659 TSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLV 718

Query: 584 ----PQSLL----GG---PPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVD---GAPT 629
               P+ LL    GG   P  +     +    N  AG+      A A  +  +   GA  
Sbjct: 719 HQAAPERLLPPAPGGLQPPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAV 778

Query: 630 SLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLS 689
           +    G  +  E+F      G          T K   LV            C +C +  +
Sbjct: 779 AGAGGGASSGPERFSCA-TCGQSFKHFLGLVTHKYVHLVRRT-------LGCGLCGQSFA 830

Query: 690 CQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFT 749
               L +H R+H  +R F+C +CG+ F     L  H   H  + P R    C +C + F 
Sbjct: 831 GAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYR----CGVCGRGFL 886

Query: 750 NAVVLQQHIRMHMG 763
            +  L+QH  +H G
Sbjct: 887 RSWYLRQHRVVHTG 900



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 3/88 (3%)

Query: 678  PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
            P +C  C +    +S L  H R H GER ++C+ CG+ F    ++  H    RA  P R 
Sbjct: 931  PQRCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRH---QRAHEPPRA 987

Query: 738  QHSCPICQKKFTNAVVLQQHIRMHMGGQ 765
            +  CP C K F +    ++H+  H GG+
Sbjct: 988  ELRCPACLKAFKDPGYFRKHLAAHQGGR 1015



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 59/226 (26%), Positives = 80/226 (35%), Gaps = 15/226 (6%)

Query: 952  GRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCR 1011
            G  G      + LL   R   +     C VCGK F   + L  H R HT++RP+ C +C 
Sbjct: 823  GLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCG 882

Query: 1012 RGCSTMGNLKQHLLTHR-LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGK 1070
            RG      L+QH + H   +     +    FA   S +    + + A        +  GK
Sbjct: 883  RGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVAR---PQRCSACGK 939

Query: 1071 AMA----LGEGPPLPAGVQVPAGPQTVMG-----PGLAPMLAPPPRRTPKQHNCQSCGKT 1121
                   L E   L  G +         G       L    A  P R   +  C +C K 
Sbjct: 940  TFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHEPPRA--ELRCPACLKA 997

Query: 1122 FSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNN 1167
            F      + H   H G +PF C+ CG  F     LK H   H   N
Sbjct: 998  FKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAEN 1043



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C +C R       L+ H   HTGER FKC +C + F    +L  H  +H    P R 
Sbjct: 875 PYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQR- 933

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
              C  C K F     L +H R+H+G
Sbjct: 934 ---CSACGKTFRYRSNLLEHQRLHLG 956



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           +C +C +     + L  H R HT +RP++C +CGR F     L+ H  VH  +   +   
Sbjct: 849 RCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFK--- 905

Query: 740 SCPICQKKFTNAVVLQQHIRMH 761
            C +C K+F  +  L +H R+H
Sbjct: 906 -CGVCAKRFAQSSSLAEHRRLH 926



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 24/67 (35%), Positives = 33/67 (49%)

Query: 405  SVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLK 464
            SV   + + E P  + +C  C K F      + HL +H G RPF+C+ CG  F+    LK
Sbjct: 974  SVLRHQRAHEPPRAELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLK 1033

Query: 465  VHFQRHK 471
             H   HK
Sbjct: 1034 KHRLAHK 1040



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 21/50 (42%), Positives = 26/50 (52%)

Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
           KC  CAK F   S+L  H R H   RP +C+ CG  F  + NL  H + H
Sbjct: 905 KCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLH 954



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 19/54 (35%), Positives = 27/54 (50%)

Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168
            C  C K F+ +S+L  H R H   +P  C+ CG+ F  + NL  H   H+   A
Sbjct: 906  CGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERA 959



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 20/56 (35%), Positives = 28/56 (50%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475
           ++C  C + F     L+ H   HTGER FKC +C  RF+   +L  H + H    P
Sbjct: 876 YRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARP 931



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 17/53 (32%), Positives = 23/53 (43%)

Query: 680  QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAK 732
            +C  C +        + H   H G RPF+C  CG  F     LK H   H+A+
Sbjct: 990  RCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAE 1042



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 18/51 (35%), Positives = 25/51 (49%)

Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           +C  C K F   S L  H R H GER ++C  CG  F    ++  H + H+
Sbjct: 933 RCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHE 983



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 18/54 (33%), Positives = 24/54 (44%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKEL 1032
            C  C K F        H  +H   RPF C+ C  G +    LK+H L H+ + L
Sbjct: 991  CPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAENL 1044


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
            sapiens]
          Length = 1059

 Score =  131 bits (329), Expect = 5e-30
 Identities = 236/1025 (23%), Positives = 329/1025 (32%), Gaps = 236/1025 (23%)

Query: 184  GARAAGGSGAGG--GVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQ---RPPP 238
            GA   G SG GG  GV   + P   + L  L  Q+   ++L  +    VA +     PPP
Sbjct: 9    GAGGGGSSGIGGEDGVHFQSYPF--DFLEFLNHQRFEPMELYGEHAKAVAALPCAPGPPP 66

Query: 239  RPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESG 298
            +P       P  P P     P     P S   P A +  S  ++ ++   +   S   S 
Sbjct: 67   QP-------PPQPPPPQYDYP-----PQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSS 114

Query: 299  ASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAA---SSQPQSASTPPALAPGSLLGAA 355
            +S+     +P  P A  A P P   A  P PQ      S             P S  G  
Sbjct: 115  SSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVT 174

Query: 356  PGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAED 415
            PGL +P                      A A  PL A  +   G PP  +  +P    + 
Sbjct: 175  PGLGAP----------------------AGAPGPLPAPSQTPPG-PPAAAACDPTKDDKG 211

Query: 416  PFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475
             F + K                    +  ER F C +C   F    +L  H   H  + P
Sbjct: 212  YFRRLK--------------------YLMERRFPCGVCQKSFKQSSHLVQHMLVHSGERP 251

Query: 476  HIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVP 535
            +                       G+       V++ +  +     VP + G    P  P
Sbjct: 252  Y---------------------ECGVCGRTYNHVSSLIRHRRCHKDVPPAAG---GPPQP 287

Query: 536  GAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTK 595
            G H     P   PA        PA+S                +ATA +P ++  GPP T 
Sbjct: 288  GPHL---PPLGLPA--------PAAS----------------AATAAAPSTVSSGPPATP 320

Query: 596  AEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDS 655
              P            AP  A  SAAP  V   P + G                 GG    
Sbjct: 321  VAP------------AP-SADGSAAPAGVGVPPPATG-----------------GG---- 346

Query: 656  MQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRA 715
                                  P  C +C +V    S L  H   HTGE+PF C +C ++
Sbjct: 347  --------------------DGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKS 386

Query: 716  FTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMH----MGGQIPNTP- 770
            F  + +LK H   H A     ++  C IC K F +A  L +H   H     GG  P  P 
Sbjct: 387  FNRRESLKRHVKTHSAD---LLRLPCGICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPC 443

Query: 771  -LPEGFQDAMDSELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGS- 828
             L      A  S L +   +A   ++ +   D            AA+ P  P     G  
Sbjct: 444  DLCGKSYSAPQSLLRHKAAHAPPAAAAEAPKD-----------GAASAPQPPPTFPPGPY 492

Query: 829  -CPPSPPSVISSIAALENQMKMIDSV----MSCQQLT---GLKSVENGSGESDRLSNDSS 880
              PP PP+  S  AA      +  +V    +    L       S   GSG S        
Sbjct: 493  LLPPDPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCC 552

Query: 881  SAVGDLESRSAGSPALSESSSSQALSPAPSNGESFR-----SKSPGLGAPEEPQEIPL-- 933
               G    R           + +     P  G+ FR     SK   +   E P +  L  
Sbjct: 553  GICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCELCG 612

Query: 934  -------------KTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCG 980
                         +  R   P A  G+ G P   G            S       S  C 
Sbjct: 613  KVFGYPQSLTRHRQVHRLQLPCALAGAAGLPSTQGTPGACGPGASGTSAGPTDGLSYACS 672

Query: 981  VCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPN 1040
             CG+ F     +  H   H  E+P+ C  C +    + NL  H L H  +  P +L  P 
Sbjct: 673  DCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLVH--QAAPERLLPP- 729

Query: 1041 FALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQ--VPAGPQTVMGPGL 1098
                P    P   SS         V  +G A  +G      AGV     AG   V G G 
Sbjct: 730  ---APGGLQPPDGSSGTDA---ASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAVAGAGG 783

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                       P++ +C +CG++F     L  H+  H   +  GC +CG++F    +L +
Sbjct: 784  GASSG------PERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLL 837

Query: 1159 HMGTH 1163
            H  +H
Sbjct: 838  HRRSH 842



 Score =  111 bits (278), Expect = 4e-24
 Identities = 168/753 (22%), Positives = 238/753 (31%), Gaps = 184/753 (24%)

Query: 37  ADSGPESRSGGEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDA---------P 87
           A  G  S  GGE+    +    +F    +FL HQR      P+ +  E A         P
Sbjct: 10  AGGGGSSGIGGEDGVHFQSYPFDFL---EFLNHQR----FEPMELYGEHAKAVAALPCAP 62

Query: 88  APPPEDFPEPSPA--SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAP 145
            PPP+  P+P P     P +      AE   +  +   +      +    +  +   + P
Sbjct: 63  GPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKP 122

Query: 146 RP--PPAAPAPPTPAYGA--PSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAA 201
            P  PPA  APP P + A  P+    +  L   +       +G  A+G     G  A A 
Sbjct: 123 DPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVTPGLGAPAG 182

Query: 202 VPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPS----- 256
            P                                P P PS +P   P+A    P+     
Sbjct: 183 AP-------------------------------GPLPAPSQTPPGPPAAAACDPTKDDKG 211

Query: 257 ---QLPGLAALPLSAGAPAAAIAGSGPAAP--AAFEGAQPLSRPESGAS----------- 300
              +L  L       G    +   S           G +P      G +           
Sbjct: 212 YFRRLKYLMERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHR 271

Query: 301 --------TPGGPAEPSAPAAPSAAPAPAA-PAPAPAPQSAASSQPQSASTPPALAPGSL 351
                     GGP +P     P   PAPAA  A A AP + +S  P +   P   A GS 
Sbjct: 272 RCHKDVPPAAGGPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSA 331

Query: 352 LGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKA 411
             A  G+P P      A+G                                         
Sbjct: 332 APAGVGVPPP------ATG----------------------------------------- 344

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
             + PF    C  C KVF   S L  H   HTGE+PF C++C   F+ + +LK H + H 
Sbjct: 345 GGDGPF---ACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHS 401

Query: 472 EKYPHIQMN---------PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTV 522
                +             Y +     +    +G P                 +PV P  
Sbjct: 402 ADLLRLPCGICGKAFRDASYLLKHQAAHAGAGAGGP-----------------RPVYPCD 444

Query: 523 PTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAE 582
                   P ++   H  A +P A  A       + A     +  PG             
Sbjct: 445 LCGKSYSAPQSLL-RHKAAHAPPAAAAEAPKDGAASAPQPPPTFPPG------------- 490

Query: 583 SPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTS-LGSPGLPAVSE 641
            P  L   PP T +E  +        G  PV     A P  + GA TS  G  G     +
Sbjct: 491 -PYLLPPDPPTTDSEKAAAAAAAVVYGAVPV-PLLGAHPLLLGGAGTSGAGGSGASVPGK 548

Query: 642 QFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTH 701
            F       G        ET K  + +   +K    P+QC +C +       L  H+  H
Sbjct: 549 TFCCGICGRG----FGRRETLKRHERIHTGEK----PHQCPVCGKRFRESFHLSKHHVVH 600

Query: 702 TGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734
           T ERP+KC++CG+ F    +L  H  VHR + P
Sbjct: 601 TRERPYKCELCGKVFGYPQSLTRHRQVHRLQLP 633



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 164/674 (24%), Positives = 225/674 (33%), Gaps = 122/674 (18%)

Query: 147 PPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGA-----GGGVAAAA 201
           PP   PAP   A  A + +       +T VA A  + G+ A  G G      GGG    A
Sbjct: 292 PPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFA 351

Query: 202 VPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGL 261
            PL  +     +   +HQ Q+I       +         S S     S      +    L
Sbjct: 352 CPLCWKVFK--KPSHLHQHQIIHTGEKPFSCSVC-----SKSFNRRESLKRHVKTHSADL 404

Query: 262 AALPLSAGAPA-----------AAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSA 310
             LP      A           AA AG+G   P       P        S P       A
Sbjct: 405 LRLPCGICGKAFRDASYLLKHQAAHAGAGAGGPRP---VYPCDLCGKSYSAPQSLLRHKA 461

Query: 311 PAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASG 370
             AP     PAA A AP   +A++ QP     PP   PG      P L  P  P T +  
Sbjct: 462 AHAP-----PAAAAEAPKDGAASAPQP-----PPTFPPG------PYLLPPDPPTTDSE- 504

Query: 371 VIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFG 430
                   + AA      P+  L  H        +     + A  P     C  C + FG
Sbjct: 505 ----KAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCCGICGRGFG 560

Query: 431 SDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDN 490
               L+ H R HTGE+P +C +CG RF    +L  H   H  + P+              
Sbjct: 561 RRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPY-------------K 607

Query: 491 VPTCSGI-PYGMSLPPEKPVTTWLDSKPVLP-TVPTSVGLQLPPTVPGAHGYADSPSATP 548
              C  +  Y  SL   + V      +  LP  +  + GL      PGA G    P A+ 
Sbjct: 608 CELCGKVFGYPQSLTRHRQV-----HRLQLPCALAGAAGLPSTQGTPGACG----PGASG 658

Query: 549 ASRSPQRP-SPASSECASLSPGLNHVES-----------GVSATAES------------- 583
            S  P    S A S+C    P L HV S           G  A  ++             
Sbjct: 659 TSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLV 718

Query: 584 ----PQSLL----GG---PPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVD---GAPT 629
               P+ LL    GG   P  +     +    N  AG+      A A  +  +   GA  
Sbjct: 719 HQAAPERLLPPAPGGLQPPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAV 778

Query: 630 SLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLS 689
           +    G  +  E+F      G          T K   LV            C +C +  +
Sbjct: 779 AGAGGGASSGPERFSCA-TCGQSFKHFLGLVTHKYVHLVRRT-------LGCGLCGQSFA 830

Query: 690 CQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFT 749
               L +H R+H  +R F+C +CG+ F     L  H   H  + P R    C +C + F 
Sbjct: 831 GAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYR----CGVCGRGFL 886

Query: 750 NAVVLQQHIRMHMG 763
            +  L+QH  +H G
Sbjct: 887 RSWYLRQHRVVHTG 900



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 3/88 (3%)

Query: 678  PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
            P +C  C +    +S L  H R H GER ++C+ CG+ F    ++  H    RA  P R 
Sbjct: 931  PQRCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRH---QRAHEPPRP 987

Query: 738  QHSCPICQKKFTNAVVLQQHIRMHMGGQ 765
            +  CP C K F +    ++H+  H GG+
Sbjct: 988  ELRCPACLKAFKDPGYFRKHLAAHQGGR 1015



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 59/226 (26%), Positives = 80/226 (35%), Gaps = 15/226 (6%)

Query: 952  GRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCR 1011
            G  G      + LL   R   +     C VCGK F   + L  H R HT++RP+ C +C 
Sbjct: 823  GLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCG 882

Query: 1012 RGCSTMGNLKQHLLTHR-LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGK 1070
            RG      L+QH + H   +     +    FA   S +    + + A        +  GK
Sbjct: 883  RGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVAR---PQRCSACGK 939

Query: 1071 AMA----LGEGPPLPAGVQVPAGPQTVMG-----PGLAPMLAPPPRRTPKQHNCQSCGKT 1121
                   L E   L  G +         G       L    A  P R   +  C +C K 
Sbjct: 940  TFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHEPPR--PELRCPACLKA 997

Query: 1122 FSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNN 1167
            F      + H   H G +PF C+ CG  F     LK H   H   N
Sbjct: 998  FKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAEN 1043



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C +C R       L+ H   HTGER FKC +C + F    +L  H  +H    P R 
Sbjct: 875 PYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQR- 933

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
              C  C K F     L +H R+H+G
Sbjct: 934 ---CSACGKTFRYRSNLLEHQRLHLG 956



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           +C +C +     + L  H R HT +RP++C +CGR F     L+ H  VH  +   +   
Sbjct: 849 RCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFK--- 905

Query: 740 SCPICQKKFTNAVVLQQHIRMH 761
            C +C K+F  +  L +H R+H
Sbjct: 906 -CGVCAKRFAQSSSLAEHRRLH 926



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 24/67 (35%), Positives = 33/67 (49%)

Query: 405  SVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLK 464
            SV   + + E P  + +C  C K F      + HL +H G RPF+C+ CG  F+    LK
Sbjct: 974  SVLRHQRAHEPPRPELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLK 1033

Query: 465  VHFQRHK 471
             H   HK
Sbjct: 1034 KHRLAHK 1040



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 21/50 (42%), Positives = 26/50 (52%)

Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
           KC  CAK F   S+L  H R H   RP +C+ CG  F  + NL  H + H
Sbjct: 905 KCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLH 954



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 19/54 (35%), Positives = 27/54 (50%)

Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168
            C  C K F+ +S+L  H R H   +P  C+ CG+ F  + NL  H   H+   A
Sbjct: 906  CGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERA 959



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 20/56 (35%), Positives = 28/56 (50%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475
           ++C  C + F     L+ H   HTGER FKC +C  RF+   +L  H + H    P
Sbjct: 876 YRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARP 931



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 19/58 (32%), Positives = 28/58 (48%)

Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQ 478
           +C  C K F   S L  H R H GER ++C  CG  F    ++  H + H+   P ++
Sbjct: 933 RCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHEPPRPELR 990



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 17/53 (32%), Positives = 23/53 (43%)

Query: 680  QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAK 732
            +C  C +        + H   H G RPF+C  CG  F     LK H   H+A+
Sbjct: 990  RCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAE 1042



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 19/58 (32%), Positives = 25/58 (43%)

Query: 975  PSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKEL 1032
            P   C  C K F        H  +H   RPF C+ C  G +    LK+H L H+ + L
Sbjct: 987  PELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAENL 1044


>gi|148276998 zinc finger protein 628 [Homo sapiens]
          Length = 1055

 Score =  127 bits (318), Expect = 9e-29
 Identities = 139/553 (25%), Positives = 188/553 (33%), Gaps = 110/553 (19%)

Query: 678  PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
            P  C  C +     S+L+ H   HTGERP+ C +CG++FT   NL+ H  VH  + P R 
Sbjct: 143  PYPCPDCPKAFKNSSSLRRHRHVHTGERPYTCGVCGKSFTQSTNLRQHQRVHTGERPFR- 201

Query: 738  QHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTP--------------------------- 770
               CP+C K FT++  L  H R H     P T                            
Sbjct: 202  ---CPLCPKTFTHSSNLLLHQRTHGAAPAPGTASAAPPPQSREPGKVFVCDAYLQRHLQP 258

Query: 771  ----------------LPEGFQDAMDS--ELAYDDKNAETLSSYDDDMDENSMEDDAELK 812
                            +PE F  A ++  EL Y     E   S ++ + E+         
Sbjct: 259  HSPPAPPAPPPPPPPVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEH---QPCPGP 315

Query: 813  DAATDPAK-PLLSYAGSCPPSP-PSVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSG 870
            DAA  P + P  +     PPSP P      AA       +    S + + GL   ++  G
Sbjct: 316  DAAPQPQEAPAEAPKADQPPSPLPQPPPPAAAPAPGFACLPCGKSFRTVAGLSRHQHSHG 375

Query: 871  ESDRLSNDSSSAVGD--------------LESRSAGSPALSESSSSQALSPAPSNGESFR 916
             +   +    S  G               +E  +AG P     ++       P       
Sbjct: 376  AAGGQAFRCGSCDGSFPQLASLLAHQQCHVEEAAAGRPPPQAEAAEVTCPQEP------- 428

Query: 917  SKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPS 976
              +P    P  P   P   ERP   A    S    G +G++         L    G+ P 
Sbjct: 429  -LAPAAPVPPPPPSAPASAERPYKCAECGKS--FKGSSGLR-------YHLRDHTGERPY 478

Query: 977  TVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQL 1036
              CG CGK F   S L IH R HT  R F C  C        + + HL  H         
Sbjct: 479  Q-CGECGKAFKRSSLLAIHQRVHTGLRAFTCGQCGLTFKWSSHYQYHLRLH--------- 528

Query: 1037 FDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP 1096
                     S   P                   + +  GE P    GV    G       
Sbjct: 529  ---------SGERPYACGECGKAFRNTSCLRRHRHVHTGERPH-ACGV---CGKSFAQTS 575

Query: 1097 GLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNL 1156
             L           P    C  C KTF+ +S L +H+RTH+ E+PF C ICGR F     L
Sbjct: 576  NLRQHQRVHTGERP--FRCPLCPKTFTHSSNLLLHQRTHSAERPFTCPICGRGFVMAAYL 633

Query: 1157 KVHMGTHMWNNAP 1169
            + H+ TH   N P
Sbjct: 634  QRHLRTHAPANTP 646



 Score =  115 bits (289), Expect = 2e-25
 Identities = 122/501 (24%), Positives = 170/501 (33%), Gaps = 136/501 (27%)

Query: 681  CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740
            C  C       S  + H R HTGERP+ C  C +AF    +L+ H  VH  + P    ++
Sbjct: 118  CGQCGLAFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNSSSLRRHRHVHTGERP----YT 173

Query: 741  CPICQKKFTNAVVLQQHIRMHMGGQIPNTPL-PEGFQDAMDSELAYDDKNAE----TLSS 795
            C +C K FT +  L+QH R+H G +    PL P+ F  + +  L      A     T S+
Sbjct: 174  CGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAPAPGTASA 233

Query: 796  YDDDMDENS---MEDDAELK---DAATDPAKPLLSYAGSCPPSPPSVISS--IAALENQM 847
                           DA L+      + PA P      + PP PP V+    +AA E  +
Sbjct: 234  APPPQSREPGKVFVCDAYLQRHLQPHSPPAPP------APPPPPPPVVPELFLAAAETTV 287

Query: 848  KMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSP 907
            +++     C+Q                                        SS    L  
Sbjct: 288  ELVYRCDGCEQ--------------------------------------GFSSEELLLEH 309

Query: 908  APSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFL 967
             P          PG  A  +PQE P +  + D P +       P  A             
Sbjct: 310  QP---------CPGPDAAPQPQEAPAEAPKADQPPSPLPQPPPPAAA------------- 347

Query: 968  SRERGKCPSTVCGVCGKPFACKSALEIHYRSH--TKERPFVCALCRRGCSTMGNLKQHLL 1025
                   P   C  CGK F   + L  H  SH     + F C  C      + +L  H  
Sbjct: 348  -----PAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRCGSCDGSFPQLASLLAHQQ 402

Query: 1026 THRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQ 1085
             H                         +  AA                 G  PP     +
Sbjct: 403  CH-------------------------VEEAA----------------AGRPPPQAEAAE 421

Query: 1086 VPAGPQTVMGPGLAPMLAPP---PRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFG 1142
            V   PQ  + P  AP+  PP   P    + + C  CGK+F  +S L+ H R HTGE+P+ 
Sbjct: 422  VTC-PQEPLAPA-APVPPPPPSAPASAERPYKCAECGKSFKGSSGLRYHLRDHTGERPYQ 479

Query: 1143 CTICGRAFTTKGNLKVHMGTH 1163
            C  CG+AF     L +H   H
Sbjct: 480  CGECGKAFKRSSLLAIHQRVH 500



 Score = 94.0 bits (232), Expect = 8e-19
 Identities = 141/633 (22%), Positives = 216/633 (34%), Gaps = 145/633 (22%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH--------- 470
           + C  C K F   + L+ H R HTGERPF+C +C   F+   NL +H + H         
Sbjct: 172 YTCGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAPAPGTA 231

Query: 471 ------KEKYP------------HIQMNPYPVPEY--------------------LDNVP 492
                 + + P            H+Q +  P P                      ++ V 
Sbjct: 232 SAAPPPQSREPGKVFVCDAYLQRHLQPHSPPAPPAPPPPPPPVVPELFLAAAETTVELVY 291

Query: 493 TCSGIPYGMSL------------------PPEKPVTTWLDSKPVLPTVPTSVGLQLPPTV 534
            C G   G S                   P E P       +P     P+ +    PP  
Sbjct: 292 RCDGCEQGFSSEELLLEHQPCPGPDAAPQPQEAPAEAPKADQP-----PSPLPQPPPPAA 346

Query: 535 PGAHGYADSPSA----TPASRSPQRPSPASS-----ECASLSPGLNHVESGVSATAESPQ 585
             A G+A  P      T A  S  + S  ++      C S       + S ++      +
Sbjct: 347 APAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRCGSCDGSFPQLASLLAHQQCHVE 406

Query: 586 SLLGGPPLTKAEPVSLPCTNAR-AGDAPVGAQASAAPTSVDG-------APTSLGSPGLP 637
               G P  +AE   + C     A  APV     +AP S +          +  GS GL 
Sbjct: 407 EAAAGRPPPQAEAAEVTCPQEPLAPAAPVPPPPPSAPASAERPYKCAECGKSFKGSSGLR 466

Query: 638 AVSEQFKAQFPF--GGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALK 695
                   + P+  G    + + S    + Q V    +  T    C  C       S  +
Sbjct: 467 YHLRDHTGERPYQCGECGKAFKRSSLLAIHQRVHTGLRAFT----CGQCGLTFKWSSHYQ 522

Query: 696 MHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQ 755
            H R H+GERP+ C  CG+AF     L+ H  VH  + P    H+C +C K F     L+
Sbjct: 523 YHLRLHSGERPYACGECGKAFRNTSCLRRHRHVHTGERP----HACGVCGKSFAQTSNLR 578

Query: 756 QHIRMHMGGQIPNTPL-PEGFQDAMDSELAYDDKNAE------------TLSSYDDDMDE 802
           QH R+H G +    PL P+ F  + +  L     +AE             +++Y      
Sbjct: 579 QHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFTCPICGRGFVMAAY------ 632

Query: 803 NSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGL 862
             ++        A  P       AG  PP+P +   +  A ++       V+   Q T  
Sbjct: 633 --LQRHLRTHAPANTPPSTTAPAAGPQPPAPLAAARAPPATQDV-----HVLPHLQATLS 685

Query: 863 KSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSPGL 922
             V  G+ ++  L   + ++   L  ++A    L  SS      P P             
Sbjct: 686 LEVAGGTAQAPSLGPAAPNSQTFLLVQTAQGLQLIPSSVQPPTPPPP------------- 732

Query: 923 GAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAG 955
             P  P+ I L       P+++ G+GG   R G
Sbjct: 733 --PAPPKLILL-------PSSSAGAGGGRARQG 756



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 79/256 (30%), Positives = 97/256 (37%), Gaps = 38/256 (14%)

Query: 242 LSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGA------QPLSRP 295
           L P + P+ P P P   P +  L L+A      +          F         QP   P
Sbjct: 256 LQPHSPPAPPAPPPPPPPVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGP 315

Query: 296 ESGASTPGGPAE-PSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAP------ 348
           ++       PAE P A   PS  P P  PA APAP  A     +S  T   L+       
Sbjct: 316 DAAPQPQEAPAEAPKADQPPSPLPQPPPPAAAPAPGFACLPCGKSFRTVAGLSRHQHSHG 375

Query: 349 ---------GSLLGAAPGLPSPLLPQT-----SASGVIFPNPLVSIAATANALDPLSALM 394
                    GS  G+ P L S L  Q      +A+G   P      A  A    P   L 
Sbjct: 376 AAGGQAFRCGSCDGSFPQLASLLAHQQCHVEEAAAGRPPPQ-----AEAAEVTCPQEPLA 430

Query: 395 KHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICG 454
                 PP  S     ASAE P+   KC  C K F   S L+ HLR HTGERP++C  CG
Sbjct: 431 PAAPVPPPPPSA---PASAERPY---KCAECGKSFKGSSGLRYHLRDHTGERPYQCGECG 484

Query: 455 NRFSTKGNLKVHFQRH 470
             F     L +H + H
Sbjct: 485 KAFKRSSLLAIHQRVH 500



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 105/400 (26%), Positives = 145/400 (36%), Gaps = 69/400 (17%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP---- 475
           + C  C K F + S+L+ H   HTGERP+ C +CG  F+   NL+ H + H  + P    
Sbjct: 144 YPCPDCPKAFKNSSSLRRHRHVHTGERPYTCGVCGKSFTQSTNLRQHQRVHTGERPFRCP 203

Query: 476 --------------HIQMN-PYPVPEYLDNVPTCSGIPYGMSLPPEKPVT--TWLDS--K 516
                         H + +   P P       T S  P   S  P K      +L    +
Sbjct: 204 LCPKTFTHSSNLLLHQRTHGAAPAP------GTASAAPPPQSREPGKVFVCDAYLQRHLQ 257

Query: 517 PVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLS----PGLNH 572
           P  P  P +     PP VP     A   +     R        SSE   L     PG + 
Sbjct: 258 PHSPPAPPAPPPPPPPVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGPDA 317

Query: 573 VESGVSATAESPQ-----SLLGGPPLTKAEP----VSLPC----------TNARAGDAPV 613
                 A AE+P+     S L  PP   A P      LPC          +  +      
Sbjct: 318 APQPQEAPAEAPKADQPPSPLPQPPPPAAAPAPGFACLPCGKSFRTVAGLSRHQHSHGAA 377

Query: 614 GAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLV----- 668
           G QA     S DG+   L S  L A  +    +   G      + +E +  Q+ +     
Sbjct: 378 GGQAFRC-GSCDGSFPQLAS--LLAHQQCHVEEAAAGRPPPQAEAAEVTCPQEPLAPAAP 434

Query: 669 -----ENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLK 723
                 +       P +C  C +     S L+ H R HTGERP++C  CG+AF     L 
Sbjct: 435 VPPPPPSAPASAERPYKCAECGKSFKGSSGLRYHLRDHTGERPYQCGECGKAFKRSSLLA 494

Query: 724 THFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
            H  VH     LR   +C  C   F  +   Q H+R+H G
Sbjct: 495 IHQRVHTG---LRA-FTCGQCGLTFKWSSHYQYHLRLHSG 530



 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 154/668 (23%), Positives = 206/668 (30%), Gaps = 167/668 (25%)

Query: 47  GEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSER 106
           GE    C  C   F   ++ L HQR+          H  APAP       P  +  P + 
Sbjct: 196 GERPFRCPLCPKTFTHSSNLLLHQRT----------HGAAPAPGTASAAPPPQSREPGKV 245

Query: 107 AESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNV 166
              +A  +   +                          P  PPA PAPP P    P    
Sbjct: 246 FVCDAYLQRHLQ--------------------------PHSPPAPPAPPPPP--PPVVPE 277

Query: 167 TLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQI 226
              A   T V +     G      S               E+L+ L+ Q         Q 
Sbjct: 278 LFLAAAETTVELVYRCDGCEQGFSS---------------EELL-LEHQPCPGPDAAPQP 321

Query: 227 RSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAG-------SG 279
           +   A      P+    P+  P  P PA +  PG A LP   G     +AG        G
Sbjct: 322 QEAPA----EAPKADQPPSPLPQPPPPAAAPAPGFACLP--CGKSFRTVAGLSRHQHSHG 375

Query: 280 PAAPAAFE---------------GAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPA 324
            A   AF                  Q     E+ A  P   AE +    P    APAAP 
Sbjct: 376 AAGGQAFRCGSCDGSFPQLASLLAHQQCHVEEAAAGRPPPQAEAAEVTCPQEPLAPAAPV 435

Query: 325 PAPAPQSAASSQPQSASTPPALAP-GSLLGAAPGLPSPLLPQTSA--------------S 369
           P P P     S P SA  P   A  G     + GL   L   T                S
Sbjct: 436 PPPPP-----SAPASAERPYKCAECGKSFKGSSGLRYHLRDHTGERPYQCGECGKAFKRS 490

Query: 370 GVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVF 429
            ++  +  V     A          K       ++ +     S E P+    C  C K F
Sbjct: 491 SLLAIHQRVHTGLRAFTCGQCGLTFKWSSHYQYHLRLH----SGERPY---ACGECGKAF 543

Query: 430 GSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP-------------- 475
            + S L+ H   HTGERP  C +CG  F+   NL+ H + H  + P              
Sbjct: 544 RNTSCLRRHRHVHTGERPHACGVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSS 603

Query: 476 --------HIQMNPYPVP---------EYLD---------NVPTCSGIPYGMSLPPEKPV 509
                   H    P+  P          YL          N P  +  P     PP  P+
Sbjct: 604 NLLLHQRTHSAERPFTCPICGRGFVMAAYLQRHLRTHAPANTPPSTTAPAAGPQPP-APL 662

Query: 510 TTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPG 569
                + P    V     LQ   ++  A G A +PS  PA+     P+  +      + G
Sbjct: 663 AA-ARAPPATQDVHVLPHLQATLSLEVAGGTAQAPSLGPAA-----PNSQTFLLVQTAQG 716

Query: 570 LNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPT 629
           L  + S V       Q     PP    + + LP ++A AG    G +A   P +V  A  
Sbjct: 717 LQLIPSSV-------QPPTPPPPPAPPKLILLPSSSAGAG----GGRARQGPRAVGKAGQ 765

Query: 630 SLGSPGLP 637
             G   LP
Sbjct: 766 GAGVVWLP 773



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 62/228 (27%), Positives = 86/228 (37%), Gaps = 51/228 (22%)

Query: 942  AAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTK 1001
            + A G+G  PG A     A +                CG CGK F   S L  H R+HT 
Sbjct: 12   STAEGAGEKPGPAAPAPAAQYE---------------CGECGKSFRWSSRLLHHQRTHTG 56

Query: 1002 ERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMI 1061
            ERP+ C  C +       L  H   H   E P Q  D           P     ++   I
Sbjct: 57   ERPYKCPDCPKAFKGSSALLYHQRGH-TGERPYQCPD----------CPKAFKRSSLLQI 105

Query: 1062 KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHN------C 1115
               V+   +A   G+                    GLA   +   +   +QH       C
Sbjct: 106  HRSVHTGLRAFICGQ-------------------CGLAFKWSSHYQYHLRQHTGERPYPC 146

Query: 1116 QSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
              C K F ++S+L+ H   HTGE+P+ C +CG++FT   NL+ H   H
Sbjct: 147  PDCPKAFKNSSSLRRHRHVHTGERPYTCGVCGKSFTQSTNLRQHQRVH 194



 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 68/249 (27%), Positives = 87/249 (34%), Gaps = 53/249 (21%)

Query: 972  GKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKE 1031
            G+ P T CGVCGK F   + L  H R HT ERPF C LC +  +   NL  H  TH    
Sbjct: 168  GERPYT-CGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAP 226

Query: 1032 LPS--------QLFDPNFAL-----------------------GPSQSTPSLISSAAPTM 1060
             P         Q  +P                            P    P L  +AA T 
Sbjct: 227  APGTASAAPPPQSREPGKVFVCDAYLQRHLQPHSPPAPPAPPPPPPPVVPELFLAAAETT 286

Query: 1061 IKMEVN------GHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQ-- 1112
            +++         G      L E  P P      A PQ    P  AP    PP   P+   
Sbjct: 287  VELVYRCDGCEQGFSSEELLLEHQPCPGP---DAAPQPQEAPAEAPKADQPPSPLPQPPP 343

Query: 1113 --------HNCQSCGKTFSSASALQIHERTH--TGEKPFGCTICGRAFTTKGNLKVHMGT 1162
                      C  CGK+F + + L  H+ +H   G + F C  C  +F    +L  H   
Sbjct: 344  PAAAPAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRCGSCDGSFPQLASLLAHQQC 403

Query: 1163 HMWNNAPAR 1171
            H+   A  R
Sbjct: 404  HVEEAAAGR 412



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 54/178 (30%), Positives = 65/178 (36%), Gaps = 49/178 (27%)

Query: 979  CGVCGK-------------------PFAC---------KSALEIHYRSHTKERPFVCALC 1010
            CGVCGK                   PF C          S L +H R+H+ ERPF C +C
Sbjct: 564  CGVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFTCPIC 623

Query: 1011 RRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAP------------ 1058
             RG      L++HL TH     P     P  A GP    P   + A P            
Sbjct: 624  GRGFVMAAYLQRHLRTHAPANTPPSTTAP--AAGPQPPAPLAAARAPPATQDVHVLPHLQ 681

Query: 1059 TMIKMEVNGHGKAMALGEGPPLPAG-----VQVPAGPQTVMGPGLAPMLAPPPRRTPK 1111
              + +EV G G A A   GP  P       VQ   G Q +    + P   PPP   PK
Sbjct: 682  ATLSLEVAG-GTAQAPSLGPAAPNSQTFLLVQTAQGLQLIPS-SVQPPTPPPPPAPPK 737



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 30/76 (39%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 1088 AGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICG 1147
            A   T  G G  P  A P      Q+ C  CGK+F  +S L  H+RTHTGE+P+ C  C 
Sbjct: 9    APASTAEGAGEKPGPAAPAPAA--QYECGECGKSFRWSSRLLHHQRTHTGERPYKCPDCP 66

Query: 1148 RAFTTKGNLKVHMGTH 1163
            +AF     L  H   H
Sbjct: 67   KAFKGSSALLYHQRGH 82



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 25/69 (36%), Positives = 35/69 (50%)

Query: 408 EPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHF 467
           +P  +A  P  +++C  C K F   S L  H R+HTGERP+KC  C   F     L  H 
Sbjct: 20  KPGPAAPAPAAQYECGECGKSFRWSSRLLHHQRTHTGERPYKCPDCPKAFKGSSALLYHQ 79

Query: 468 QRHKEKYPH 476
           + H  + P+
Sbjct: 80  RGHTGERPY 88



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 22/51 (43%), Positives = 27/51 (52%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
           +KC  C K F   SAL  H R HTGERP++C  C   F     L++H   H
Sbjct: 60  YKCPDCPKAFKGSSALLYHQRGHTGERPYQCPDCPKAFKRSSLLQIHRSVH 110



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 31/96 (32%), Positives = 43/96 (44%), Gaps = 20/96 (20%)

Query: 391 SALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKC 450
           SAL+ H++G            + E P+   +C  C K F   S LQIH   HTG R F C
Sbjct: 73  SALLYHQRGH-----------TGERPY---QCPDCPKAFKRSSLLQIHRSVHTGLRAFIC 118

Query: 451 NICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPE 486
             CG  F    + + H ++H  +       PYP P+
Sbjct: 119 GQCGLAFKWSSHYQYHLRQHTGE------RPYPCPD 148



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 73/286 (25%), Positives = 100/286 (34%), Gaps = 58/286 (20%)

Query: 28  AAPGEGAEDADSGPESRSGGEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAP 87
           AAP  G   A   P+SR  G+   VC+               Q      PP        P
Sbjct: 224 AAPAPGTASAAPPPQSREPGK-VFVCDAYLQRHL--------QPHSPPAPPA------PP 268

Query: 88  APPPEDFPEPSPASSPSERAESEAAEEAGAEGAEGEARPVEKE------AEPMDAE-PAG 140
            PPP   PE   A++ +   E     +   +G   E   +E +      A P   E PA 
Sbjct: 269 PPPPPVVPELFLAAAETT-VELVYRCDGCEQGFSSEELLLEHQPCPGPDAAPQPQEAPAE 327

Query: 141 DTRAPRPPPAAPAPPTPAYGAPSTN---VTLEALLSTKVAVAQFSQGARAAGGSGAGGGV 197
             +A +PP   P PP PA  AP+     +       T   +++      AAGG     G 
Sbjct: 328 APKADQPPSPLPQPPPPA-AAPAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRCGS 386

Query: 198 AAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQ 257
              + P  L  L+A QQ  + +           A   RPPP+   +    P  P      
Sbjct: 387 CDGSFPQ-LASLLAHQQCHVEE-----------AAAGRPPPQAEAAEVTCPQEP------ 428

Query: 258 LPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPG 303
                       APAA +    P+APA+ E  +P    E G S  G
Sbjct: 429 -----------LAPAAPVPPPPPSAPASAE--RPYKCAECGKSFKG 461



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 21/55 (38%), Positives = 26/55 (47%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           C  C   F   S  Q HLR HTGERP+ C  C   F    +L+ H   H  + P+
Sbjct: 118 CGQCGLAFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNSSSLRRHRHVHTGERPY 172



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 53/260 (20%), Positives = 80/260 (30%), Gaps = 76/260 (29%)

Query: 978  VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKE-----L 1032
            +CG CG  F   S  + H R HT ERP+ C  C +      +L++H   H  +      +
Sbjct: 117  ICGQCGLAFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNSSSLRRHRHVHTGERPYTCGV 176

Query: 1033 PSQLFDPNFALGPSQST------------PSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080
              + F  +  L   Q              P   + ++  ++    +G   A       P 
Sbjct: 177  CGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAPAPGTASAAPP 236

Query: 1081 P------------AGVQVPAGPQTVMGPGLAPMLAPPPRRTPK------------QHNCQ 1116
            P            A +Q    P +   P   P   PPP   P+             + C 
Sbjct: 237  PQSREPGKVFVCDAYLQRHLQPHSPPAPPAPP--PPPPPVVPELFLAAAETTVELVYRCD 294

Query: 1117 SCGKTFSSASALQIHE-----------RTHTGEKP----------------------FGC 1143
             C + FSS   L  H+           +    E P                      F C
Sbjct: 295  GCEQGFSSEELLLEHQPCPGPDAAPQPQEAPAEAPKADQPPSPLPQPPPPAAAPAPGFAC 354

Query: 1144 TICGRAFTTKGNLKVHMGTH 1163
              CG++F T   L  H  +H
Sbjct: 355  LPCGKSFRTVAGLSRHQHSH 374



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 29/92 (31%), Positives = 34/92 (36%)

Query: 936  ERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIH 995
            E+P   A AP +    G  G        LL   R         C  C K F   SAL  H
Sbjct: 19   EKPGPAAPAPAAQYECGECGKSFRWSSRLLHHQRTHTGERPYKCPDCPKAFKGSSALLYH 78

Query: 996  YRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
             R HT ERP+ C  C +       L+ H   H
Sbjct: 79   QRGHTGERPYQCPDCPKAFKRSSLLQIHRSVH 110



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 77/307 (25%), Positives = 99/307 (32%), Gaps = 61/307 (19%)

Query: 883  VGDLESRSAGSPALSESSSSQALSPAPSN-------GESFRSKSPGLGAPE-EPQEIPLK 934
            VG     +  S A          +PAP+        G+SFR  S  L        E P K
Sbjct: 2    VGSHADMAPASTAEGAGEKPGPAAPAPAAQYECGECGKSFRWSSRLLHHQRTHTGERPYK 61

Query: 935  TERPDSPAAAPGSGGAP-GRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALE 993
               PD P A  GS      + G   E P+          +CP      C K F   S L+
Sbjct: 62   C--PDCPKAFKGSSALLYHQRGHTGERPY----------QCPD-----CPKAFKRSSLLQ 104

Query: 994  IHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLI 1053
            IH   HT  R F+C  C        + + HL  H   E P           P    P   
Sbjct: 105  IHRSVHTGLRAFICGQCGLAFKWSSHYQYHLRQH-TGERPY----------PCPDCPKAF 153

Query: 1054 SSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQH 1113
             +++       V+        GE  P   GV    G        L           P   
Sbjct: 154  KNSSSLRRHRHVH-------TGE-RPYTCGV---CGKSFTQSTNLRQHQRVHTGERP--F 200

Query: 1114 NCQSCGKTFSSASALQIHERTHTGEKPFGCTIC----------GRAFTTKGNLKVHMGTH 1163
             C  C KTF+ +S L +H+RTH G  P   T            G+ F     L+ H+  H
Sbjct: 201  RCPLCPKTFTHSSNLLLHQRTH-GAAPAPGTASAAPPPQSREPGKVFVCDAYLQRHLQPH 259

Query: 1164 MWNNAPA 1170
                 PA
Sbjct: 260  SPPAPPA 266



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 63/284 (22%), Positives = 90/284 (31%), Gaps = 37/284 (13%)

Query: 138 PAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGV 197
           PA    +   P A P PP P   A +   T +  +   +   Q +     AGG+     +
Sbjct: 642 PANTPPSTTAPAAGPQPPAPLAAARAPPATQDVHVLPHL---QATLSLEVAGGTAQAPSL 698

Query: 198 AAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQ 257
             AA          L  Q    LQLI                 S+ P   P  P P    
Sbjct: 699 GPAAP----NSQTFLLVQTAQGLQLIPS---------------SVQPPTPPPPPAP---- 735

Query: 258 LPGLAALPLSAGAPAAAIAGSGP-AAPAAFEGAQPLSRP-ESGASTPGGPAEPSAPAAPS 315
            P L  LP S+       A  GP A   A +GA  +  P   G    G  +  ++    S
Sbjct: 736 -PKLILLPSSSAGAGGGRARQGPRAVGKAGQGAGVVWLPGPGGLGVQGAASAGASGTGQS 794

Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375
                        PQ  +  Q Q     P +    L  A       L P    + V    
Sbjct: 795 LIVLQNVGGGEAGPQEMSGVQLQPLRPAPEVTTVQLQPAQEVTTVQLQPAQEVTTVQL-Q 853

Query: 376 PLVSIAATANALDPLSALMKHRKG-----KPPNVSVFEPKASAE 414
           P   +  T   L P++  + +  G     + PN+ V +  A+ E
Sbjct: 854 PAQEV--TTVQLQPVAGQLSNSSGGAVATEAPNLLVVQSGAAEE 895



 Score = 31.6 bits (70), Expect = 5.2
 Identities = 68/270 (25%), Positives = 88/270 (32%), Gaps = 35/270 (12%)

Query: 133 PMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSG 192
           P    PA   + P P  AA AP  PA         L+A LS +V           AGG+ 
Sbjct: 647 PSTTAPAAGPQPPAPLAAARAP--PATQDVHVLPHLQATLSLEV-----------AGGTA 693

Query: 193 AGGGVAAAAVPLILEQLMALQQQQIHQLQLI-EQIRSQVALMQRPPPRPSLSPAAAPSAP 251
               +  AA          L  Q    LQLI   ++         PP+  L P+++  A 
Sbjct: 694 QAPSLGPAAP----NSQTFLLVQTAQGLQLIPSSVQPPTPPPPPAPPKLILLPSSSAGAG 749

Query: 252 GPAPSQLPGLAALPLSAGAPAAAIAGSGP-------AAPAAFEG-AQPLSRPESGASTPG 303
           G    Q P        AG  A  +   GP       AA A   G  Q L   ++      
Sbjct: 750 GGRARQGPRAVG---KAGQGAGVVWLPGPGGLGVQGAASAGASGTGQSLIVLQNVGGGEA 806

Query: 304 GPAEPSAPAAPSAAPAPAAPAPAPAPQSAASS---QPQSASTPPALAPGSLLGAAPGLPS 360
           GP E S        PAP        P    ++   QP    T   L P   +      P 
Sbjct: 807 GPQEMSGVQLQPLRPAPEVTTVQLQPAQEVTTVQLQPAQEVTTVQLQPAQEVTTVQLQPV 866

Query: 361 PLLPQTSASGVI---FPNPLVSIAATANAL 387
                 S+ G +    PN LV  +  A  L
Sbjct: 867 AGQLSNSSGGAVATEAPNLLVVQSGAAEEL 896


>gi|69885084 p120E4F [Homo sapiens]
          Length = 784

 Score =  111 bits (278), Expect = 4e-24
 Identities = 114/483 (23%), Positives = 171/483 (35%), Gaps = 81/483 (16%)

Query: 681  CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740
            C +CH+     S LK H  TH+  +  +CK+CG +F TKG+L  H   H  + P    + 
Sbjct: 194  CALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERP----YK 249

Query: 741  CPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSELAYDDKNAETLSSYDDDM 800
            C  C K F  +  L +H++         TP  E  + ++  ++    ++A    S     
Sbjct: 250  CSKCGKSFRESGALTRHLKSL-------TPCTEKIRFSVSKDVVVSKEDARA-GSGAGAA 301

Query: 801  DENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLT 860
               +       +   T P   L++ A        +VI  +     ++ +    ++ +   
Sbjct: 302  GLGTATSSVTGEPIETSPVIHLVTDAKG------TVIHEVHVQMQELSLGMKALAPEPPV 355

Query: 861  GLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSP 920
              +   +  G  + L + +    G +  R+AG           AL PAP+ G S      
Sbjct: 356  SQELPCSSEGSRENLLHQAMQNSGIVLERAAGEEG--------ALEPAPAAGSS------ 401

Query: 921  GLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCG 980
                   PQ  PL    P  P              + E  P      S       +  C 
Sbjct: 402  -------PQ--PLAVAAPQLP--------------VLEVQPLETQVASEASAVPRTHPCP 438

Query: 981  VCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPN 1040
             C + F   + LE H R HT  RPF CA C +       LK+H   H        + +  
Sbjct: 439  QCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVH--------VRERR 490

Query: 1041 FALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLP-AGVQVPAGPQTVMGPGLA 1099
            F  G        I+          V GH +  +     P P  G +             A
Sbjct: 491  FRCGDCGKLYKTIA---------HVRGHRRVHSDERPYPCPKCGKRYKTKN--------A 533

Query: 1100 PMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVH 1159
              +        K H CQ C + F    +L  H R HTGEKPF C  CGR F   G L  H
Sbjct: 534  QQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRH 593

Query: 1160 MGT 1162
            + T
Sbjct: 594  LRT 596



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 114/505 (22%), Positives = 177/505 (35%), Gaps = 70/505 (13%)

Query: 305 PAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGS-------------- 350
           PA P+  A       PAAP P   P + A    ++AS    ++  S              
Sbjct: 91  PATPATTALLGQEVVPAAPGPEE-PITVAHIVVEAASLAADISHASDLVGGGHIKEVIVA 149

Query: 351 ---LLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVF 407
               LG      +P  P+    G+        +    N        + H+  K    S+ 
Sbjct: 150 AEAELGDGEMAEAPGSPRQQGLGLAGEGEQAQVKLLVNKDGRYVCALCHKTFKTG--SIL 207

Query: 408 EPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHF 467
           +           H+C+ C   F +  +L  H R HT ERP+KC+ CG  F   G L  H 
Sbjct: 208 KAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCSKCGKSFRESGALTRHL 267

Query: 468 QRHKEKYPHIQMNPYPVPEYL----DNVPTCSGI-PYGMSLPPEKPVTTWLDSKPVL--- 519
              K   P  +   + V + +    ++    SG    G+           +++ PV+   
Sbjct: 268 ---KSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTATSSVTGEPIETSPVIHLV 324

Query: 520 ----PTVPTSVGLQLPPTVPGAHGYADSPSAT---PASRSPQRPSPASSECASLSPGLNH 572
                TV   V +Q+     G    A  P  +   P S    R +       +    L  
Sbjct: 325 TDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSRENLLHQAMQNSGIVLER 384

Query: 573 VESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTS------VDG 626
                 A   +P +     PL  A P  LP    +  +  V ++ASA P +       + 
Sbjct: 385 AAGEEGALEPAPAAGSSPQPLAVAAP-QLPVLEVQPLETQVASEASAVPRTHPCPQCSET 443

Query: 627 APTSL-------GSPG-LPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDP 678
            PT+        G  G  P    Q    FP   LL         K  Q V   +++    
Sbjct: 444 FPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLL---------KKHQEVHVRERRF--- 491

Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738
            +C  C ++    + ++ H R H+ ERP+ C  CG+ + TK   + HF  H  + P    
Sbjct: 492 -RCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKP---- 546

Query: 739 HSCPICQKKFTNAVVLQQHIRMHMG 763
           H C  C + F     L +H+R H G
Sbjct: 547 HVCQFCSRGFREKGSLVRHVRHHTG 571



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 1/86 (1%)

Query: 1079 PLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGE 1138
            P P  V  P  P   + P L   +A      P+ H C  C +TF +A+ L+ H+R HTG 
Sbjct: 402  PQPLAVAAPQLPVLEVQP-LETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGP 460

Query: 1139 KPFGCTICGRAFTTKGNLKVHMGTHM 1164
            +PF C  CG+AF     LK H   H+
Sbjct: 461  RPFACAQCGKAFPKAYLLKKHQEVHV 486



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 79/323 (24%), Positives = 124/323 (38%), Gaps = 54/323 (16%)

Query: 164 TNVTLEALLSTKVAVAQFSQGARAAGGSGAGG-GVAAAAV---PL----ILEQLMALQQQ 215
           T  T +   S    V    + ARA  G+GA G G A ++V   P+    ++  +   +  
Sbjct: 271 TPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGT 330

Query: 216 QIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAI 275
            IH++ +  Q++     M+   P P +S     S+ G   + L             AA  
Sbjct: 331 VIHEVHV--QMQELSLGMKALAPEPPVSQELPCSSEGSRENLLHQAMQNSGIVLERAAGE 388

Query: 276 AGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPS-AAPAPAAPAPAPAPQSAAS 334
            G+   APAA    QPL+      + P  P     P     A+ A A P   P PQ + +
Sbjct: 389 EGALEPAPAAGSSPQPLA-----VAAPQLPVLEVQPLETQVASEASAVPRTHPCPQCSET 443

Query: 335 SQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALM 394
                                   P+    +    G   P P  + A    A      L 
Sbjct: 444 -----------------------FPTAATLEAHKRGHTGPRPF-ACAQCGKAFPKAYLLK 479

Query: 395 KHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICG 454
           KH++     V V E +          +C  C K++ + + ++ H R H+ ERP+ C  CG
Sbjct: 480 KHQE-----VHVRERR---------FRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCG 525

Query: 455 NRFSTKGNLKVHFQRHKEKYPHI 477
            R+ TK   +VHF+ H E+ PH+
Sbjct: 526 KRYKTKNAQQVHFRTHLEEKPHV 548



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 46/187 (24%), Positives = 76/187 (40%), Gaps = 21/187 (11%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPA 1170
            K H C+ CG +F +  +L  H R HT E+P+ C+ CG++F   G L      H+ +  P 
Sbjct: 218  KDHECKLCGASFRTKGSLIRHHRRHTDERPYKCSKCGKSFRESGALT----RHLKSLTPC 273

Query: 1171 RRGRRLSVENPMALLGGDALKFSEMFQKDLAARAMNV--DPSFWNQYAAAITNGLAMKNN 1228
                R SV   + +   DA   S      L     +V  +P   +     +T+       
Sbjct: 274  TEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKG---- 329

Query: 1229 EISVIQNGGIPQLPVSLGGSALPPLGSMASGMDKARTGSSPPI---------VSLDKASS 1279
              +VI    +    +SLG  AL P   ++  +  +  GS   +         + L++A+ 
Sbjct: 330  --TVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSRENLLHQAMQNSGIVLERAAG 387

Query: 1280 ETAASRP 1286
            E  A  P
Sbjct: 388  EEGALEP 394



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 22/53 (41%), Positives = 30/53 (56%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            + + C  CGK + + +A Q+H RTH  EKP  C  C R F  KG+L  H+  H
Sbjct: 517  RPYPCPKCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHH 569



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 22/48 (45%), Positives = 26/48 (54%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTH 725
           P+ C  C R    + +L  H R HTGE+PFKC  CGR F   G L  H
Sbjct: 546 PHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRH 593



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 18/54 (33%), Positives = 32/54 (59%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHM 1164
            ++  C  CGK + + + ++ H R H+ E+P+ C  CG+ + TK   +VH  TH+
Sbjct: 489  RRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHL 542



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 4/117 (3%)

Query: 1048 STPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPR 1107
            S+P  ++ AAP +  +EV      +A  E   +P     P   +T   P  A + A    
Sbjct: 400  SSPQPLAVAAPQLPVLEVQPLETQVA-SEASAVPRTHPCPQCSETF--PTAATLEAHKRG 456

Query: 1108 RT-PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
             T P+   C  CGK F  A  L+ H+  H  E+ F C  CG+ + T  +++ H   H
Sbjct: 457  HTGPRPFACAQCGKAFPKAYLLKKHQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVH 513



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 21/49 (42%), Positives = 27/49 (55%)

Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            C  C KTF + S L+ H  TH+  K   C +CG +F TKG+L  H   H
Sbjct: 194  CALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRH 242



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 7/88 (7%)

Query: 942  AAAPGSGGAPGR--AGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSH 999
            A APGS    G   AG  E+A   LL       K    VC +C K F   S L+ H  +H
Sbjct: 160  AEAPGSPRQQGLGLAGEGEQAQVKLLV-----NKDGRYVCALCHKTFKTGSILKAHMVTH 214

Query: 1000 TKERPFVCALCRRGCSTMGNLKQHLLTH 1027
            +  +   C LC     T G+L +H   H
Sbjct: 215  SSRKDHECKLCGASFRTKGSLIRHHRRH 242



 Score = 37.4 bits (85), Expect = 0.094
 Identities = 45/146 (30%), Positives = 58/146 (39%), Gaps = 26/146 (17%)

Query: 24  APEHAAPGEGAEDADSG------PESRSGGEETSVCEKCCAEFFKWADFLEH--QRSCTK 75
           A E A     A  A SG      P S    ++   C +C AEF    DF++H  Q++C +
Sbjct: 25  AGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRCGRCQAEFTALEDFVQHKIQKACQR 84

Query: 76  LPP----------VLIVHEDAPAPP-PEDFPEPSPASSPSERAESEAAEEAGAEGAEGEA 124
            PP           L+  E  PA P PE   EP   +     A S AA+ + A    G  
Sbjct: 85  APPEALPATPATTALLGQEVVPAAPGPE---EPITVAHIVVEAASLAADISHASDLVGGG 141

Query: 125 R----PVEKEAEPMDAEPAGDTRAPR 146
                 V  EAE  D E A    +PR
Sbjct: 142 HIKEVIVAAEAELGDGEMAEAPGSPR 167


>gi|22749325 zinc finger protein 48 [Homo sapiens]
          Length = 618

 Score =  106 bits (265), Expect = 1e-22
 Identities = 139/545 (25%), Positives = 189/545 (34%), Gaps = 125/545 (22%)

Query: 681  CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG----NLKTHFG--VHRAKPP 734
            C  C +     S L  H RTHTGE+P+KC +CG+ F        + +TH G   +RA+PP
Sbjct: 114  CGECGKSFRQMSDLVKHQRTHTGEKPYKCGVCGKGFGDSSARIKHQRTHSGEKPYRARPP 173

Query: 735  L----RVQHS----------CPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMD 780
                 ++  S          C  C K F  +  L +H R H G      P   G      
Sbjct: 174  AQGPPKIPRSRIPAGERPTICGECGKSFRLSSDLVKHQRTHTG----EKPYKCGICGKGF 229

Query: 781  SELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSI 840
             + +   K+  T                +    AAT   K        C       + S 
Sbjct: 230  GDSSARIKHQRTHRGEQPPRPVVPRRQPSRAATAATQGPK-AQDKPYICTDCGKRFVLSC 288

Query: 841  AALENQMKMI------------------DSVMSCQQLTGLKSV---ENGSGESDRLSNDS 879
            + L +Q   +                  D V   +  TG K     E G G +D     S
Sbjct: 289  SLLSHQRSHLGPKPFGCDVCGKEFARGSDLVKHLRVHTGEKPYLCPECGKGFAD-----S 343

Query: 880  SSAVGDLESRSAGSP-ALSE-----SSSSQALSPAPSNGESFRSKSPGLGAP---EEPQE 930
            S+ V  L + S   P A  E     S SS  L    ++ E      PG   P     P  
Sbjct: 344  SARVKHLRTHSGERPHACPECDRTFSLSSTLLRHRLTHMEPQDFSFPGYPLPALIPSPPP 403

Query: 931  IPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTV-------CGVCG 983
             PL T  P +P +   SG   G  G++ E          + G+ P  +       C  CG
Sbjct: 404  PPLGTSPPLTPRSPSHSGEPFGLPGLEPEPG------GPQAGEPPPPLAGDKPHKCPECG 457

Query: 984  KPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKEL----PSQLFDP 1039
            K F   S L  H+R HT E+P++C  C +G +      +HL THR +      PS L  P
Sbjct: 458  KGFRRSSDLVKHHRVHTGEKPYLCPECGKGFADSSARVKHLRTHRGERARPPPPSTLLRP 517

Query: 1040 NFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLA 1099
            +   GP                                        VP  P+        
Sbjct: 518  HNPPGP----------------------------------------VPMAPR-------- 529

Query: 1100 PMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVH 1159
            P +   P    + H C  CGK F  +S L  H RTHTGEKP+ C  CG+ F        H
Sbjct: 530  PRVRAQPSGPSQPHVCGFCGKEFPRSSDLVKHRRTHTGEKPYKCAECGKGFGDSSARIKH 589

Query: 1160 MGTHM 1164
               H+
Sbjct: 590  QRGHL 594



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 73/215 (33%), Positives = 85/215 (39%), Gaps = 38/215 (17%)

Query: 978  VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037
            +C  CGK FA  SA   H R+H+ ERP  C  C R  S    L +H LTH          
Sbjct: 332  LCPECGKGFADSSARVKHLRTHSGERPHACPECDRTFSLSSTLLRHRLTH---------M 382

Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097
            +P     P    P+LI S  P               LG  PPL       +G    + PG
Sbjct: 383  EPQDFSFPGYPLPALIPSPPPP-------------PLGTSPPLTPRSPSHSGEPFGL-PG 428

Query: 1098 LAPMLA-------PPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAF 1150
            L P          PPP    K H C  CGK F  +S L  H R HTGEKP+ C  CG+ F
Sbjct: 429  LEPEPGGPQAGEPPPPLAGDKPHKCPECGKGFRRSSDLVKHHRVHTGEKPYLCPECGKGF 488

Query: 1151 TTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALL 1185
                    H+ TH        RG R     P  LL
Sbjct: 489  ADSSARVKHLRTH--------RGERARPPPPSTLL 515



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 131/520 (25%), Positives = 183/520 (35%), Gaps = 113/520 (21%)

Query: 678  PNQCVICHRVLSCQSALKMHYRTHTGERPFK------------------------CKICG 713
            P +C +C +     SA   H RTH+GE+P++                        C  CG
Sbjct: 139  PYKCGVCGKGFGDSSARIKHQRTHSGEKPYRARPPAQGPPKIPRSRIPAGERPTICGECG 198

Query: 714  RAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPE 773
            ++F    +L  H   H  + P    + C IC K F ++    +H R H G Q P   +P 
Sbjct: 199  KSFRLSSDLVKHQRTHTGEKP----YKCGICGKGFGDSSARIKHQRTHRGEQPPRPVVPR 254

Query: 774  GFQDAMDSELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSP 833
              Q +  +  A     A+       D  +  +   + L            S+ G      
Sbjct: 255  R-QPSRAATAATQGPKAQDKPYICTDCGKRFVLSCSLLSHQR--------SHLG------ 299

Query: 834  PSVISSIAALENQMKMIDSVMSCQQLTGLKSV---ENGSGESDRLSNDSSSAVGDLESRS 890
            P         +   +  D V   +  TG K     E G G +D     SS+ V  L + S
Sbjct: 300  PKPFGCDVCGKEFARGSDLVKHLRVHTGEKPYLCPECGKGFAD-----SSARVKHLRTHS 354

Query: 891  AGSP-ALSE-----SSSSQALSPAPSNGESFRSKSPGLGAPE---EPQEIPLKTERPDSP 941
               P A  E     S SS  L    ++ E      PG   P     P   PL T  P +P
Sbjct: 355  GERPHACPECDRTFSLSSTLLRHRLTHMEPQDFSFPGYPLPALIPSPPPPPLGTSPPLTP 414

Query: 942  AAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTV-------CGVCGKPFACKSALEI 994
             +   SG   G  G++ E          + G+ P  +       C  CGK F   S L  
Sbjct: 415  RSPSHSGEPFGLPGLEPEPG------GPQAGEPPPPLAGDKPHKCPECGKGFRRSSDLVK 468

Query: 995  HYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKEL----PSQLFDPNFALGPSQSTP 1050
            H+R HT E+P++C  C +G +      +HL THR +      PS L  P+   GP    P
Sbjct: 469  HHRVHTGEKPYLCPECGKGFADSSARVKHLRTHRGERARPPPPSTLLRPHNPPGPVPMAP 528

Query: 1051 SLISSAAPTMIKMEVNGHGKAMALGEGPPLP-----AGVQVPAGPQTVMGPGLAPMLAPP 1105
                 A P+                 GP  P      G + P     V            
Sbjct: 529  RPRVRAQPS-----------------GPSQPHVCGFCGKEFPRSSDLVKH---------- 561

Query: 1106 PRRT---PKQHNCQSCGKTFSSASALQIHERTHTGEKPFG 1142
             RRT    K + C  CGK F  +SA   H+R H    PFG
Sbjct: 562  -RRTHTGEKPYKCAECGKGFGDSSARIKHQRGHLVLTPFG 600



 Score = 80.9 bits (198), Expect = 7e-15
 Identities = 56/194 (28%), Positives = 75/194 (38%), Gaps = 56/194 (28%)

Query: 976  STVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQ 1035
            + VCG CGK F   S L  H R+HT E+P+ C +C +G        +H  TH  ++    
Sbjct: 111  AAVCGECGKSFRQMSDLVKHQRTHTGEKPYKCGVCGKGFGDSSARIKHQRTHSGEK---- 166

Query: 1036 LFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095
               P  A  P+Q                             GPP     ++PAG +  + 
Sbjct: 167  ---PYRARPPAQ-----------------------------GPPKIPRSRIPAGERPTI- 193

Query: 1096 PGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGN 1155
                               C  CGK+F  +S L  H+RTHTGEKP+ C ICG+ F     
Sbjct: 194  -------------------CGECGKSFRLSSDLVKHQRTHTGEKPYKCGICGKGFGDSSA 234

Query: 1156 LKVHMGTHMWNNAP 1169
               H  TH     P
Sbjct: 235  RIKHQRTHRGEQPP 248



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 97/408 (23%), Positives = 135/408 (33%), Gaps = 100/408 (24%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481
           C  C K F   S L  H R+HTGE+P+KC ICG  F        H + H+ + P   + P
Sbjct: 194 CGECGKSFRLSSDLVKHQRTHTGEKPYKCGICGKGFGDSSARIKHQRTHRGEQPPRPVVP 253

Query: 482 YPVPEYLDNVPT----------------------CSGIPYGMSLPPEKPV------TTWL 513
              P       T                      CS + +  S    KP         + 
Sbjct: 254 RRQPSRAATAATQGPKAQDKPYICTDCGKRFVLSCSLLSHQRSHLGPKPFGCDVCGKEFA 313

Query: 514 DSKPVLPTVPTSVGLQLPPTVPG-AHGYADSPSATPASRSPQRPSPASSECASLSPGLNH 572
               ++  +    G + P   P    G+ADS +     R+     P +      +  L+ 
Sbjct: 314 RGSDLVKHLRVHTG-EKPYLCPECGKGFADSSARVKHLRTHSGERPHACPECDRTFSLSS 372

Query: 573 VESGVSATAESPQSL-LGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSL 631
                  T   PQ     G PL    P   P         P+G      P S   +    
Sbjct: 373 TLLRHRLTHMEPQDFSFPGYPLPALIPSPPP--------PPLGTSPPLTPRSPSHSGEPF 424

Query: 632 GSPGL---PAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVL 688
           G PGL   P   +  +   P  G                    DK    P++C  C +  
Sbjct: 425 GLPGLEPEPGGPQAGEPPPPLAG--------------------DK----PHKCPECGKGF 460

Query: 689 SCQSALKMHYRTHTGERPFKCKICGRAFTTKG----NLKTHFGVHRAKPP---------- 734
              S L  H+R HTGE+P+ C  CG+ F        +L+TH G  RA+PP          
Sbjct: 461 RRSSDLVKHHRVHTGEKPYLCPECGKGFADSSARVKHLRTHRG-ERARPPPPSTLLRPHN 519

Query: 735 ------------LRVQ-------HSCPICQKKFTNAVVLQQHIRMHMG 763
                       +R Q       H C  C K+F  +  L +H R H G
Sbjct: 520 PPGPVPMAPRPRVRAQPSGPSQPHVCGFCGKEFPRSSDLVKHRRTHTG 567



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 83/307 (27%), Positives = 107/307 (34%), Gaps = 43/307 (14%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481
           C  C K F   S L  HLR HTGE+P+ C  CG  F+       H + H  + PH     
Sbjct: 305 CDVCGKEFARGSDLVKHLRVHTGEKPYLCPECGKGFADSSARVKHLRTHSGERPH----- 359

Query: 482 YPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYA 541
              PE  D   + S       L   +P        P+   +P+      PP  P      
Sbjct: 360 -ACPE-CDRTFSLSSTLLRHRLTHMEPQDFSFPGYPLPALIPS------PPPPP----LG 407

Query: 542 DSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSL 601
            SP  TP  RSP      S E   L PGL     G       PQ+    PPL   +P   
Sbjct: 408 TSPPLTP--RSPSH----SGEPFGL-PGLEPEPGG-------PQAGEPPPPLAGDKPHKC 453

Query: 602 P-CTNA--RAGD------APVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGL 652
           P C     R+ D         G +    P    G   S             +A+ P    
Sbjct: 454 PECGKGFRRSSDLVKHHRVHTGEKPYLCPECGKGFADSSARVKHLRTHRGERARPPPPST 513

Query: 653 LDSMQTSETSKLQQLVENIDKKMTDPNQ---CVICHRVLSCQSALKMHYRTHTGERPFKC 709
           L                 +  + + P+Q   C  C +     S L  H RTHTGE+P+KC
Sbjct: 514 LLRPHNPPGPVPMAPRPRVRAQPSGPSQPHVCGFCGKEFPRSSDLVKHRRTHTGEKPYKC 573

Query: 710 KICGRAF 716
             CG+ F
Sbjct: 574 AECGKGF 580



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 76/310 (24%), Positives = 104/310 (33%), Gaps = 44/310 (14%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481
           C  C K F   S L  H R+HTGE+P+KC +CG  F        H + H  + P+    P
Sbjct: 114 CGECGKSFRQMSDLVKHQRTHTGEKPYKCGVCGKGFGDSSARIKHQRTHSGEKPYRARPP 173

Query: 482 YPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYA 541
              P  +      S IP G                               PT+ G  G +
Sbjct: 174 AQGPPKIPR----SRIPAGER-----------------------------PTICGECGKS 200

Query: 542 DSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSL 601
              S+               +C     G        SA  +  ++  G  P     P   
Sbjct: 201 FRLSSDLVKHQRTHTGEKPYKCGICGKGF----GDSSARIKHQRTHRGEQPPRPVVPRRQ 256

Query: 602 PCTNARAGDAPVGAQASAAP-TSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSE 660
           P   A A  A  G +A   P    D     + S  L +         PFG  +   + + 
Sbjct: 257 PSRAATA--ATQGPKAQDKPYICTDCGKRFVLSCSLLSHQRSHLGPKPFGCDVCGKEFAR 314

Query: 661 TSKL-QQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTK 719
            S L + L  +  +K   P  C  C +  +  SA   H RTH+GERP  C  C R F+  
Sbjct: 315 GSDLVKHLRVHTGEK---PYLCPECGKGFADSSARVKHLRTHSGERPHACPECDRTFSLS 371

Query: 720 GNLKTHFGVH 729
             L  H   H
Sbjct: 372 STLLRHRLTH 381



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 59/246 (23%), Positives = 79/246 (32%), Gaps = 42/246 (17%)

Query: 249 SAPG-PAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAE 307
           S PG P P+ +P     PL    P    + S    P    G +P               E
Sbjct: 388 SFPGYPLPALIPSPPPPPLGTSPPLTPRSPSHSGEPFGLPGLEP---------------E 432

Query: 308 PSAPAAPSAAPAPAAPAPAPAPQSAASSQPQS---------ASTPPALAPGSLLGAAPGL 358
           P  P A    P  A   P   P+     +  S             P L P    G A   
Sbjct: 433 PGGPQAGEPPPPLAGDKPHKCPECGKGFRRSSDLVKHHRVHTGEKPYLCPECGKGFADSS 492

Query: 359 PSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFF 418
                 +T       P P  ++    N   P+    + R            +A    P  
Sbjct: 493 ARVKHLRTHRGERARPPPPSTLLRPHNPPGPVPMAPRPRV-----------RAQPSGPSQ 541

Query: 419 KHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQ 478
            H C FC K F   S L  H R+HTGE+P+KC  CG  F           R K +  H+ 
Sbjct: 542 PHVCGFCGKEFPRSSDLVKHRRTHTGEKPYKCAECGKGFGDSS------ARIKHQRGHLV 595

Query: 479 MNPYPV 484
           + P+ +
Sbjct: 596 LTPFGI 601



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 22/81 (27%), Positives = 32/81 (39%), Gaps = 24/81 (29%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFK------------------------CNICGN 455
           +KC  C K FG  SA   H R+H+GE+P++                        C  CG 
Sbjct: 140 YKCGVCGKGFGDSSARIKHQRTHSGEKPYRARPPAQGPPKIPRSRIPAGERPTICGECGK 199

Query: 456 RFSTKGNLKVHFQRHKEKYPH 476
            F    +L  H + H  + P+
Sbjct: 200 SFRLSSDLVKHQRTHTGEKPY 220


>gi|116256460 zinc finger protein 775 [Homo sapiens]
          Length = 537

 Score =  104 bits (259), Expect = 6e-22
 Identities = 79/225 (35%), Positives = 96/225 (42%), Gaps = 49/225 (21%)

Query: 978  VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR--------- 1028
            +C  CGK F   S+L IH R HT ERP+ C  C R  S   NL +HL  H          
Sbjct: 282  ICNECGKSFTWWSSLNIHQRIHTGERPYACPECGRRFSQKPNLTRHLRNHTGERPHPCPH 341

Query: 1029 -----------LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEG 1077
                       LK L + L  P     P  S      S A       +  H +A A+ E 
Sbjct: 342  CGRGFRQKQHLLKHLRTHL--PGAQAAPCPSCGKSCRSRAA------LRAHQRAHAVAE- 392

Query: 1078 PPLPAGVQVPAGPQTVMGPGLAP-----MLAPPPRRT--------------PKQHNCQSC 1118
            P +PAG +    PQ    PGLA        +P  R T              P+Q  C  C
Sbjct: 393  PAVPAG-EPGDQPQAEAIPGLAARPRSSQRSPGARDTLWGRGQAGLAGPGEPRQFICNEC 451

Query: 1119 GKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            GK+FS  SAL IH+R HTGE+P+ C  CGR F+ K NL  H   H
Sbjct: 452  GKSFSWWSALTIHQRIHTGERPYPCPECGRRFSQKPNLTRHRRNH 496



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 65/196 (33%), Positives = 84/196 (42%), Gaps = 10/196 (5%)

Query: 978  VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPS--- 1034
            +CG CGK F+ K  L  H R HT ERPF C  C R  S   +L +H  TH      S   
Sbjct: 136  LCGKCGKSFSQKPNLARHQRHHTGERPFCCPECARRFSQKQHLLKHQKTHSRPATHSCPE 195

Query: 1035 --QLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQT 1092
              + F     L   Q   +     +   +   +       A    P  P G    A    
Sbjct: 196  CERCFRHQVGLRIHQRAHARDRQGSRAGLHELIQDAAARRACRLQPGPPRGRPEWAWLGL 255

Query: 1093 VMG----PGL-APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICG 1147
              G    PG  A +  P     P+Q  C  CGK+F+  S+L IH+R HTGE+P+ C  CG
Sbjct: 256  CQGWWGQPGARAAVSGPEGPGEPRQFICNECGKSFTWWSSLNIHQRIHTGERPYACPECG 315

Query: 1148 RAFTTKGNLKVHMGTH 1163
            R F+ K NL  H+  H
Sbjct: 316  RRFSQKPNLTRHLRNH 331



 Score = 87.8 bits (216), Expect = 6e-17
 Identities = 88/314 (28%), Positives = 107/314 (34%), Gaps = 70/314 (22%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481
           C  C K F   S+L IH R HTGERP+ C  CG RFS K NL  H + H  + PH     
Sbjct: 283 CNECGKSFTWWSSLNIHQRIHTGERPYACPECGRRFSQKPNLTRHLRNHTGERPH----- 337

Query: 482 YPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYA 541
            P P          G  +       K + T L                     PGA   A
Sbjct: 338 -PCPH--------CGRGFRQKQHLLKHLRTHL---------------------PGAQA-A 366

Query: 542 DSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSL 601
             PS   + RS           A   P +   E G    AE+   L   P  ++  P   
Sbjct: 367 PCPSCGKSCRSRAALRAHQRAHAVAEPAVPAGEPGDQPQAEAIPGLAARPRSSQRSP--- 423

Query: 602 PCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPA--VSEQFKAQFPFGGLLDSMQTS 659
                            A  T        L  PG P   +  +    F +   L   Q  
Sbjct: 424 ----------------GARDTLWGRGQAGLAGPGEPRQFICNECGKSFSWWSALTIHQRI 467

Query: 660 ETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTK 719
            T +              P  C  C R  S +  L  H R HTGERP+ C  CGR F+ K
Sbjct: 468 HTGE-------------RPYPCPECGRRFSQKPNLTRHRRNHTGERPYLCPACGRGFSQK 514

Query: 720 GNLKTHFGVHRAKP 733
            +L  H  VHRA P
Sbjct: 515 QHLLKHQRVHRAAP 528



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 35/90 (38%), Positives = 47/90 (52%), Gaps = 6/90 (6%)

Query: 677 DPNQ--CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734
           +P Q  C  C +  +  S+L +H R HTGERP+ C  CGR F+ K NL  H   H  + P
Sbjct: 277 EPRQFICNECGKSFTWWSSLNIHQRIHTGERPYACPECGRRFSQKPNLTRHLRNHTGERP 336

Query: 735 LRVQHSCPICQKKFTNAVVLQQHIRMHMGG 764
               H CP C + F     L +H+R H+ G
Sbjct: 337 ----HPCPHCGRGFRQKQHLLKHLRTHLPG 362



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 31/81 (38%), Positives = 46/81 (56%), Gaps = 4/81 (4%)

Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740
           C+ C +  S  S+LK+H RTHTGE+P+ C  CG++F+ K NL  H   H  + P      
Sbjct: 109 CLDCGKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARHQRHHTGERPF----C 164

Query: 741 CPICQKKFTNAVVLQQHIRMH 761
           CP C ++F+    L +H + H
Sbjct: 165 CPECARRFSQKQHLLKHQKTH 185



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 35/87 (40%), Positives = 46/87 (52%), Gaps = 6/87 (6%)

Query: 677 DPNQ--CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734
           +P Q  C  C +  S  SAL +H R HTGERP+ C  CGR F+ K NL  H   H  + P
Sbjct: 442 EPRQFICNECGKSFSWWSALTIHQRIHTGERPYPCPECGRRFSQKPNLTRHRRNHTGERP 501

Query: 735 LRVQHSCPICQKKFTNAVVLQQHIRMH 761
               + CP C + F+    L +H R+H
Sbjct: 502 ----YLCPACGRGFSQKQHLLKHQRVH 524



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 51/161 (31%), Positives = 68/161 (42%), Gaps = 14/161 (8%)

Query: 606 ARAGDAPVGAQASAAPTSVDG-----APTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSE 660
           A  G    G+   A PT  D      AP S   P  P++S   +  F             
Sbjct: 62  ALGGQEESGSPRWAPPTEQDAGLAGRAPGSASGPLSPSLSSG-EGHFVCLDCGKRFSWWS 120

Query: 661 TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720
           + K+ Q     +K    P  C  C +  S +  L  H R HTGERPF C  C R F+ K 
Sbjct: 121 SLKIHQRTHTGEK----PYLCGKCGKSFSQKPNLARHQRHHTGERPFCCPECARRFSQKQ 176

Query: 721 NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMH 761
           +L  H   H ++P     HSCP C++ F + V L+ H R H
Sbjct: 177 HLLKHQKTH-SRP---ATHSCPECERCFRHQVGLRIHQRAH 213



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 27/49 (55%), Positives = 34/49 (69%)

Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            C  CGK FS  S+L+IH+RTHTGEKP+ C  CG++F+ K NL  H   H
Sbjct: 109  CLDCGKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARHQRHH 157



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 32/84 (38%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C R  S +  L  H R HTGERP  C  CGR F  K +L  H   H    P   
Sbjct: 308 PYACPECGRRFSQKPNLTRHLRNHTGERPHPCPHCGRGFRQKQHLLKHLRTHL---PGAQ 364

Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761
              CP C K   +   L+ H R H
Sbjct: 365 AAPCPSCGKSCRSRAALRAHQRAH 388



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 25/53 (47%), Positives = 31/53 (58%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            K + C  CGK+FS    L  H+R HTGE+PF C  C R F+ K +L  H  TH
Sbjct: 133  KPYLCGKCGKSFSQKPNLARHQRHHTGERPFCCPECARRFSQKQHLLKHQKTH 185



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 30/65 (46%), Positives = 36/65 (55%), Gaps = 6/65 (9%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481
           C  C K F   S+L+IH R+HTGE+P+ C  CG  FS K NL  H QRH     H    P
Sbjct: 109 CLDCGKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARH-QRH-----HTGERP 162

Query: 482 YPVPE 486
           +  PE
Sbjct: 163 FCCPE 167



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 52/167 (31%), Positives = 72/167 (43%), Gaps = 34/167 (20%)

Query: 888  SRSAGSPALSESSSSQALSPAPSNGESFRSKSPGLGAP-EEPQE--IPLKTERPDSPAAA 944
            +++A  P+  +S  S+A   A     +    +   G P ++PQ   IP    RP S   +
Sbjct: 363  AQAAPCPSCGKSCRSRAALRAHQRAHAVAEPAVPAGEPGDQPQAEAIPGLAARPRSSQRS 422

Query: 945  PGSG------GAPGRAGIKEEAPFSLLFLSRERGKCPS-----TV------------CGV 981
            PG+       G  G AG  E   F    +  E GK  S     T+            C  
Sbjct: 423  PGARDTLWGRGQAGLAGPGEPRQF----ICNECGKSFSWWSALTIHQRIHTGERPYPCPE 478

Query: 982  CGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR 1028
            CG+ F+ K  L  H R+HT ERP++C  C RG S     KQHLL H+
Sbjct: 479  CGRRFSQKPNLTRHRRNHTGERPYLCPACGRGFSQ----KQHLLKHQ 521



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 47/148 (31%), Positives = 58/148 (39%), Gaps = 21/148 (14%)

Query: 332 AASSQPQSAS---TPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALD 388
           A   Q +S S    PP      L G APG         SASG + P+ L S       LD
Sbjct: 62  ALGGQEESGSPRWAPPTEQDAGLAGRAPG---------SASGPLSPS-LSSGEGHFVCLD 111

Query: 389 PLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPF 448
                   R     ++ + +   + E P+    C  C K F     L  H R HTGERPF
Sbjct: 112 -----CGKRFSWWSSLKIHQRTHTGEKPYL---CGKCGKSFSQKPNLARHQRHHTGERPF 163

Query: 449 KCNICGNRFSTKGNLKVHFQRHKEKYPH 476
            C  C  RFS K +L  H + H     H
Sbjct: 164 CCPECARRFSQKQHLLKHQKTHSRPATH 191



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 53/216 (24%), Positives = 77/216 (35%), Gaps = 48/216 (22%)

Query: 256 SQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPS 315
           + LPG  A P     P+   +    AA  A + A  ++ P   A  PG   +P A A P 
Sbjct: 358 THLPGAQAAP----CPSCGKSCRSRAALRAHQRAHAVAEPAVPAGEPGD--QPQAEAIPG 411

Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375
            A  P +   +P  +     + Q+              A PG P   +         +  
Sbjct: 412 LAARPRSSQRSPGARDTLWGRGQAGL------------AGPGEPRQFICNECGKSFSW-- 457

Query: 376 PLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSAL 435
                          SAL  H++             + E P+    C  C + F     L
Sbjct: 458 --------------WSALTIHQRIH-----------TGERPY---PCPECGRRFSQKPNL 489

Query: 436 QIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
             H R+HTGERP+ C  CG  FS K +L  H + H+
Sbjct: 490 TRHRRNHTGERPYLCPACGRGFSQKQHLLKHQRVHR 525



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 3/64 (4%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQM 479
           + C  C + F     L  HLR+HTGERP  C  CG  F  K +L  H + H    P  Q 
Sbjct: 309 YACPECGRRFSQKPNLTRHLRNHTGERPHPCPHCGRGFRQKQHLLKHLRTH---LPGAQA 365

Query: 480 NPYP 483
            P P
Sbjct: 366 APCP 369



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 18/69 (26%), Positives = 30/69 (43%)

Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGR 1174
            C  C + FS    L  H++TH+      C  C R F  +  L++H   H  +   +R G 
Sbjct: 165  CPECARRFSQKQHLLKHQKTHSRPATHSCPECERCFRHQVGLRIHQRAHARDRQGSRAGL 224

Query: 1175 RLSVENPMA 1183
               +++  A
Sbjct: 225  HELIQDAAA 233



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 4/59 (6%)

Query: 705 RPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
           R F C  CG++F+    L  H  +H  + P    + CP C ++F+    L +H R H G
Sbjct: 444 RQFICNECGKSFSWWSALTIHQRIHTGERP----YPCPECGRRFSQKPNLTRHRRNHTG 498



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 4/62 (6%)

Query: 702 TGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMH 761
           +GE  F C  CG+ F+   +LK H   H  + P    + C  C K F+    L +H R H
Sbjct: 102 SGEGHFVCLDCGKRFSWWSSLKIHQRTHTGEKP----YLCGKCGKSFSQKPNLARHQRHH 157

Query: 762 MG 763
            G
Sbjct: 158 TG 159



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 5/83 (6%)

Query: 3   RRKQAKPQHLKSDEELLPPDGAP---EHAAPGEGAEDADSGP--ESRSGGEETSVCEKCC 57
           R+   +P+ L   EE   P  AP   + A     A  + SGP   S S GE   VC  C 
Sbjct: 54  RQTMGRPRALGGQEESGSPRWAPPTEQDAGLAGRAPGSASGPLSPSLSSGEGHFVCLDCG 113

Query: 58  AEFFKWADFLEHQRSCTKLPPVL 80
             F  W+    HQR+ T   P L
Sbjct: 114 KRFSWWSSLKIHQRTHTGEKPYL 136



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 14/35 (40%), Positives = 21/35 (60%)

Query: 443 TGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
           +GE  F C  CG RFS   +LK+H + H  + P++
Sbjct: 102 SGEGHFVCLDCGKRFSWWSSLKIHQRTHTGEKPYL 136



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 22/60 (36%), Positives = 25/60 (41%), Gaps = 9/60 (15%)

Query: 20  PPDGAPEHAAPG--------EGAEDADSGPESRSGGEETSVCEKCCAEFFKWADFLEHQR 71
           PP G PE A  G         GA  A SGPE   G     +C +C   F  W+    HQR
Sbjct: 243 PPRGRPEWAWLGLCQGWWGQPGARAAVSGPEG-PGEPRQFICNECGKSFTWWSSLNIHQR 301



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%)

Query: 1110 PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            P + +    G+   SAS   +     +GE  F C  CG+ F+   +LK+H  TH
Sbjct: 77   PTEQDAGLAGRAPGSASG-PLSPSLSSGEGHFVCLDCGKRFSWWSSLKIHQRTH 129


>gi|21699088 zinc finger protein 627 [Homo sapiens]
          Length = 461

 Score =  102 bits (253), Expect = 3e-21
 Identities = 56/185 (30%), Positives = 85/185 (45%), Gaps = 24/185 (12%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+C   + IH R+HT E+P+ C  C +      +++ H  TH  ++L      
Sbjct: 253  CKQCGKAFSCSKYIRIHERTHTGEKPYECKQCGKAFRCASSVRSHERTHTGEKL------ 306

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
              F         + ++S    MIK   NG  K    G+    P+  ++     T      
Sbjct: 307  --FECKECGKALTCLASVRRHMIKHTGNGPYKCKVCGKAFDFPSSFRIHERTHT------ 358

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                        K ++C+ CGK FS +S+ + HER HTGEKP+ CT CG+AF+     ++
Sbjct: 359  ----------GEKPYDCKQCGKAFSCSSSFRKHERIHTGEKPYKCTKCGKAFSRSSYFRI 408

Query: 1159 HMGTH 1163
            H  TH
Sbjct: 409  HERTH 413



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 52/185 (28%), Positives = 83/185 (44%), Gaps = 30/185 (16%)

Query: 982  CGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNF 1041
            CG+  +   +  +  R+H   +P+ C  C     ++ ++++H+LTHR   +P +      
Sbjct: 144  CGRALSYHRSFPVRERTHPGGKPYDCKECGETFISLVSIRRHMLTHR-GGVPYKCK---- 198

Query: 1042 ALGPSQSTPSL--ISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
              G +   PSL  I   + T  K  E    GKA +            +    +T  G   
Sbjct: 199  VCGKAFDYPSLFRIHERSHTGEKPYECKQCGKAFSCSS--------YIRIHERTHTGD-- 248

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                        K + C+ CGK FS +  ++IHERTHTGEKP+ C  CG+AF    +++ 
Sbjct: 249  ------------KPYECKQCGKAFSCSKYIRIHERTHTGEKPYECKQCGKAFRCASSVRS 296

Query: 1159 HMGTH 1163
            H  TH
Sbjct: 297  HERTH 301



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 4/89 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S +++H RTHTG++P++CK CG+AF+    ++ H   H  + P   
Sbjct: 222 PYECKQCGKAFSCSSYIRIHERTHTGDKPYECKQCGKAFSCSKYIRIHERTHTGEKP--- 278

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQI 766
            + C  C K F  A  ++ H R H G ++
Sbjct: 279 -YECKQCGKAFRCASSVRSHERTHTGEKL 306



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 4/95 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +  SC S+ + H R HTGE+P+KC  CG+AF+     + H   H  + P   
Sbjct: 362 PYDCKQCGKAFSCSSSFRKHERIHTGEKPYKCTKCGKAFSRSSYFRIHERTHTGEKP--- 418

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLP 772
            + C  C K F+ +   + H ++H G +    P P
Sbjct: 419 -YECKQCGKAFSRSTYFRVHEKIHTGEKPYENPNP 452



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C +C +     S+ ++H RTHTGE+P+ CK CG+AF+   + + H  +H  + P   
Sbjct: 334 PYKCKVCGKAFDFPSSFRIHERTHTGEKPYDCKQCGKAFSCSSSFRKHERIHTGEKP--- 390

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   + H R H G
Sbjct: 391 -YKCTKCGKAFSRSSYFRIHERTHTG 415



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C +C +     S  ++H R+HTGE+P++CK CG+AF+    ++ H   H    P   
Sbjct: 194 PYKCKVCGKAFDYPSLFRIHERSHTGEKPYECKQCGKAFSCSSYIRIHERTHTGDKP--- 250

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +  ++ H R H G
Sbjct: 251 -YECKQCGKAFSCSKYIRIHERTHTG 275



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 30/86 (34%), Positives = 44/86 (51%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +   C S+++ H RTHTGE+ F+CK CG+A T   +++ H   H    P   
Sbjct: 278 PYECKQCGKAFRCASSVRSHERTHTGEKLFECKECGKALTCLASVRRHMIKHTGNGP--- 334

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C +C K F      + H R H G
Sbjct: 335 -YKCKVCGKAFDFPSSFRIHERTHTG 359



 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 4/84 (4%)

Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           +C  C + L+C ++++ H   HTG  P+KCK+CG+AF    + + H   H  + P    +
Sbjct: 308 ECKECGKALTCLASVRRHMIKHTGNGPYKCKVCGKAFDFPSSFRIHERTHTGEKP----Y 363

Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763
            C  C K F+ +   ++H R+H G
Sbjct: 364 DCKQCGKAFSCSSSFRKHERIHTG 387



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 23/57 (40%), Positives = 34/57 (59%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   S  +IH RSHTGE+P++C  CG  FS    +++H + H    P+
Sbjct: 195 YKCKVCGKAFDYPSLFRIHERSHTGEKPYECKQCGKAFSCSSYIRIHERTHTGDKPY 251



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 25/62 (40%), Positives = 35/62 (56%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQM 479
           +KC  C K F   S  +IH R+HTGE+P++C  CG  FS     +VH + H  + P+   
Sbjct: 391 YKCTKCGKAFSRSSYFRIHERTHTGEKPYECKQCGKAFSRSTYFRVHEKIHTGEKPYENP 450

Query: 480 NP 481
           NP
Sbjct: 451 NP 452



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P    + E   + E P+   +C+ C K F   S ++IH R+HTG++P++C  CG  FS  
Sbjct: 207 PSLFRIHERSHTGEKPY---ECKQCGKAFSCSSYIRIHERTHTGDKPYECKQCGKAFSCS 263

Query: 461 GNLKVHFQRHKEKYPH 476
             +++H + H  + P+
Sbjct: 264 KYIRIHERTHTGEKPY 279



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P +  + E   + E P+    C+ C K F   S+ + H R HTGE+P+KC  CG  FS  
Sbjct: 347 PSSFRIHERTHTGEKPY---DCKQCGKAFSCSSSFRKHERIHTGEKPYKCTKCGKAFSRS 403

Query: 461 GNLKVHFQRHKEKYPH 476
              ++H + H  + P+
Sbjct: 404 SYFRIHERTHTGEKPY 419



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 22/57 (38%), Positives = 34/57 (59%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   S+ +IH R+HTGE+P+ C  CG  FS   + + H + H  + P+
Sbjct: 335 YKCKVCGKAFDFPSSFRIHERTHTGEKPYDCKQCGKAFSCSSSFRKHERIHTGEKPY 391



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 7/91 (7%)

Query: 673 KKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAK 732
           KK    NQC    R LS   +  +  RTH G +P+ CK CG  F +  +++ H   HR  
Sbjct: 136 KKSYTRNQC---GRALSYHRSFPVRERTHPGGKPYDCKECGETFISLVSIRRHMLTHRGG 192

Query: 733 PPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
            P    + C +C K F    + + H R H G
Sbjct: 193 VP----YKCKVCGKAFDYPSLFRIHERSHTG 219



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C        +++ H  TH G  P+KCK+CG+AF      + H   H  + P   
Sbjct: 166 PYDCKECGETFISLVSIRRHMLTHRGGVPYKCKVCGKAFDYPSLFRIHERSHTGEKP--- 222

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +  ++ H R H G
Sbjct: 223 -YECKQCGKAFSCSSYIRIHERTHTG 247



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 18/51 (35%), Positives = 31/51 (60%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
           ++C+ C K F     ++IH R+HTGE+P++C  CG  F    +++ H + H
Sbjct: 251 YECKQCGKAFSCSKYIRIHERTHTGEKPYECKQCGKAFRCASSVRSHERTH 301



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 3/73 (4%)

Query: 404 VSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNL 463
           + + E   + E P+   +C+ C K F   S+++ H R+HTGE+ F+C  CG   +   ++
Sbjct: 266 IRIHERTHTGEKPY---ECKQCGKAFRCASSVRSHERTHTGEKLFECKECGKALTCLASV 322

Query: 464 KVHFQRHKEKYPH 476
           + H  +H    P+
Sbjct: 323 RRHMIKHTGNGPY 335



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 16/56 (28%), Positives = 31/56 (55%)

Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +C+ C K     ++++ H+  HTG  P+KC +CG  F    + ++H + H  + P+
Sbjct: 308 ECKECGKALTCLASVRRHMIKHTGNGPYKCKVCGKAFDFPSSFRIHERTHTGEKPY 363



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 19/53 (35%), Positives = 28/53 (52%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            K +    CG+  S   +  + ERTH G KP+ C  CG  F +  +++ HM TH
Sbjct: 137  KSYTRNQCGRALSYHRSFPVRERTHPGGKPYDCKECGETFISLVSIRRHMLTH 189



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 16/57 (28%), Positives = 31/57 (54%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           + C+ C + F S  +++ H+ +H G  P+KC +CG  F      ++H + H  + P+
Sbjct: 167 YDCKECGETFISLVSIRRHMLTHRGGVPYKCKVCGKAFDYPSLFRIHERSHTGEKPY 223



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 9/108 (8%)

Query: 666 QLVENIDKKMTD---PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNL 722
           Q+ + I  K T    P +  +C  V    S+L  H R HTG  P + +  G+   T+   
Sbjct: 85  QIPDGILNKKTPGVKPCESSVCGEVGMGPSSLNRHIRDHTGREPNEYQEYGKKSYTRNQC 144

Query: 723 KTHFGVHRAKP------PLRVQHSCPICQKKFTNAVVLQQHIRMHMGG 764
                 HR+ P      P    + C  C + F + V +++H+  H GG
Sbjct: 145 GRALSYHRSFPVRERTHPGGKPYDCKECGETFISLVSIRRHMLTHRGG 192



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 12/52 (23%), Positives = 24/52 (46%)

Query: 425 CAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           C +      +  +  R+H G +P+ C  CG  F +  +++ H   H+   P+
Sbjct: 144 CGRALSYHRSFPVRERTHPGGKPYDCKECGETFISLVSIRRHMLTHRGGVPY 195



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 12/69 (17%)

Query: 1107 RRTPKQHNCQS--CGKTFSSASALQIHERTHTGEKP----------FGCTICGRAFTTKG 1154
            ++TP    C+S  CG+     S+L  H R HTG +P          +    CGRA +   
Sbjct: 93   KKTPGVKPCESSVCGEVGMGPSSLNRHIRDHTGREPNEYQEYGKKSYTRNQCGRALSYHR 152

Query: 1155 NLKVHMGTH 1163
            +  V   TH
Sbjct: 153  SFPVRERTH 161


>gi|51173737 ras responsive element binding protein 1 isoform 1 [Homo
            sapiens]
          Length = 1742

 Score = 98.2 bits (243), Expect = 5e-20
 Identities = 153/635 (24%), Positives = 238/635 (37%), Gaps = 146/635 (22%)

Query: 475  PHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTV 534
            P + +   PV E L  + + + I   +S  P    T   D  P      T+    L  +V
Sbjct: 1049 PPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVADPGPASTGSNTTASDSLGGSV 1108

Query: 535  PGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAES----------P 584
            P A   A   + T    S + P+PASS  A+ SP     E G + T++           P
Sbjct: 1109 PKAATTATPAATTSPKESSEPPAPASSPEAA-SP----TEQGPAGTSKKRGRKRGMRSRP 1163

Query: 585  QSLLGGPPLTKAEPVS-----LPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAV 639
            ++  GG  L  +   +     L  T+       +          V GAP     P     
Sbjct: 1164 RANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDNTQDEVAGAPADHHGP----- 1218

Query: 640  SEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYR 699
            S++ +   P   LL + + S T+ LQ++             C  C RV    S+L+ H  
Sbjct: 1219 SDEEQGSPPEDKLLRAKRNSYTNCLQKIT------------CPHCPRVFPWASSLQRHML 1266

Query: 700  THTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIR 759
            THTG++PF C+ C   F+TK N + H         LR +H    C               
Sbjct: 1267 THTGQKPFPCQKCDAFFSTKSNCERH--------QLR-KHGVTTCS-------------- 1303

Query: 760  MHMGGQIPNTPLPE-GFQDAMDSELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDP 818
            +   G IP +   + G  D+ DS+      +AET ++  + +D  S +     ++  ++ 
Sbjct: 1304 LRRNGLIPQSKESDVGSHDSTDSQ-----SDAETAAAAGEVLDLTSRD-----REQPSEG 1353

Query: 819  AKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSND 878
            A  L   AG  P    +  ++      +    +S    ++       E  +G++D    D
Sbjct: 1354 ATELRQVAGDAPVEQATAETASPVHREEHGRGESHEPEEE----HGTEESTGDADGAEED 1409

Query: 879  SSS-----------------AVGDLESRSAGSPALSESSSSQALSPAPSNGESFR----- 916
            +SS                 A GD E+ + G+     +S  Q L+   + G+SF+     
Sbjct: 1410 ASSNQSLDLDFATKLMDFKLAEGDGEAGAGGA-----ASQEQKLA-CDTCGKSFKFLGTL 1463

Query: 917  --------------SKSPGLGAPEE-PQEIPLKTER-PDSPA----AAPGSGGAPGRAGI 956
                           K  G    EE PQ  P + E+ P++PA    +APG+G AP     
Sbjct: 1464 SRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLA 1523

Query: 957  KE-EAPFSLLFLSRERG-------KCPST---------------VCGVCGKPFACKSALE 993
            +E E P      + +R        K P T               VC VC K F     L 
Sbjct: 1524 EETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLT 1583

Query: 994  IHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR 1028
             H RSHT ERP+ C  C R  +   +L +H   H+
Sbjct: 1584 RHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQ 1618



 Score = 80.9 bits (198), Expect = 7e-15
 Identities = 118/498 (23%), Positives = 183/498 (36%), Gaps = 55/498 (11%)

Query: 11   HLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEFFKWADFLEHQ 70
            H+      +P      +    +G   A++     SG  E S C     +      FLE Q
Sbjct: 808  HILKQHLHVPEQDIESYVLAADGLGPAEAPAAEASGRGEDSGCA-ALGDCKPLTAFLEPQ 866

Query: 71   -----RSCTKLPPVLIVHEDAPAPP-PEDFPEPSPAS-----------------SPSERA 107
                 R  T+ PP  +  +  PA     DF EP   S                 SPS   
Sbjct: 867  NGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPLDFSQKGLALVQVKQENISFLSPSSLV 926

Query: 108  ESEAAEEAGAEGAEGEARPVEKE-AEPMDA----EPAGDTRAPRPPPAAPAPPTPAYGAP 162
              + + E          R  +K+ A P +A    E AG +  P P PA P P  P    P
Sbjct: 927  PYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPEEEAGSSEQPSPCPA-PGPSLPVTLGP 985

Query: 163  STNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMAL-----QQQQI 217
            S       +L + +A A     A     +    G    AVP+    L++          +
Sbjct: 986  S------GILESPMAPAP---AATPEPPAQPLQGPVQLAVPIYSSALVSSPPLVGSSALL 1036

Query: 218  HQLQLIEQIRSQVALM-QRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIA 276
                L+  +R +  L+  +PP    L P A+ +    + S  P L  L      P  A  
Sbjct: 1037 SGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTL--LKTKVADPGPAST 1094

Query: 277  GSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAP-APAPQSAASS 335
            GS   A  +  G+ P +   +  +    P E S P AP+++P  A+P    PA  S    
Sbjct: 1095 GSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAASPTEQGPAGTSKKRG 1154

Query: 336  QPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMK 395
            + +   + P    G +   + G  + +    + +     +P +  A      +   A   
Sbjct: 1155 RKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDNTQDEVAGAPAD 1214

Query: 396  HR------KGKPPNVSVFEPKASA-EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPF 448
            H       +G PP   +   K ++  +   K  C  C +VF   S+LQ H+ +HTG++PF
Sbjct: 1215 HHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTGQKPF 1274

Query: 449  KCNICGNRFSTKGNLKVH 466
             C  C   FSTK N + H
Sbjct: 1275 PCQKCDAFFSTKSNCERH 1292



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 27/51 (52%), Positives = 37/51 (72%)

Query: 1113 HNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            H+C  CGK+ SSAS+L  H   H+GE+P+ CT+CG++FTT GN+  HM  H
Sbjct: 97   HSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH 147



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 7/125 (5%)

Query: 609 GDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLV 668
           G +P G ++ + P      P  +G        E+     P    + + Q   T  ++Q  
Sbjct: 34  GGSPQGIKSPSKPPG----PNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQ-- 87

Query: 669 ENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGV 728
            N D    D + C IC + LS  S+L  H   H+GERP+KC +CG++FTT GN+  H  +
Sbjct: 88  HNTDTGGAD-HSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKI 146

Query: 729 HRAKP 733
           H   P
Sbjct: 147 HEKDP 151



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 75/265 (28%), Positives = 104/265 (39%), Gaps = 36/265 (13%)

Query: 219 QLQLIEQIRSQVALMQRPPPRPSLSP-AAAPSAPGPAP-SQLPGLAALPLSAGAPAAAIA 276
           +L  I+QI    A     PP+ SL P + AP+AP  A    +P L   PL    P   +A
Sbjct: 466 ELADIQQILKMAA---SAPPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVT--PRTVVA 520

Query: 277 GSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAP--QSAAS 334
            S P      + A P            G   PS P  P      +  A + A   QS + 
Sbjct: 521 TSTPPPLINAQQASP------------GCISPSLPPPPLKLLKGSVEAASNAHLLQSKSG 568

Query: 335 SQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALM 394
           +QP +A+      P + L   P + + L  Q S    + P  + +          L A M
Sbjct: 569 TQPHAATRLSLQQPRAELPGQPEMKTQL-EQDSIIEALLPLSMEAKIKQEITEGELKAFM 627

Query: 395 KHRKGK--PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNI 452
               GK  P    V  P            CRFC +VF     L+ H+RSH G  P++CNI
Sbjct: 628 TAPGGKKTPAMRKVLYP------------CRFCNQVFAFSGVLRAHVRSHLGISPYQCNI 675

Query: 453 CGNRFSTKGNLKVHFQRHKEKYPHI 477
           C    + K  L  H + H  + P+I
Sbjct: 676 CDYIAADKAALIRHLRTHSGERPYI 700



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 53/216 (24%), Positives = 81/216 (37%), Gaps = 26/216 (12%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C +CGK  +  S+L+ H   H+ ERP+ C +C +  +T GN+ +H+  H          D
Sbjct: 99   CSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEK--------D 150

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
            PN A   +  +P L      +  K+  +   +        P PA   V  G    +    
Sbjct: 151  PNSATATAPPSP-LKRRRLSSKRKLSHDAESE-----REDPAPAKKMVEDGQSGDL---- 200

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                    ++  +  +C  C K F     L+ H  TH+ + P  C IC   F T   L  
Sbjct: 201  -------EKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLR 252

Query: 1159 HMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSE 1194
            H             GR     NP    G   L F++
Sbjct: 253  HNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTD 288



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 26/57 (45%), Positives = 35/57 (61%), Gaps = 1/57 (1%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           H C  C K   S S+L  H+  H+GERP+KC +CG  F+T GN+  H + H EK P+
Sbjct: 97  HSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH-EKDPN 152



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 70/245 (28%), Positives = 98/245 (40%), Gaps = 53/245 (21%)

Query: 503 LPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSP---- 558
           +PP KP       KP++ T  T V    PP +  A        A+P   SP  P P    
Sbjct: 504 MPPLKP-------KPLV-TPRTVVATSTPPPLINAQ------QASPGCISPSLPPPPLKL 549

Query: 559 --ASSECASLSPGLNHVESGVSATA------ESPQSLLGGPPLTKAEPVSLPCTNARAGD 610
              S E AS +  L   +SG    A      + P++ L G P  K +   L   +     
Sbjct: 550 LKGSVEAAS-NAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQ---LEQDSIIEAL 605

Query: 611 APVGAQASAAPTSVDGA----PTSLGSPGLPAVSE-----QFKAQ-FPFGGLLDSMQTSE 660
            P+  +A       +G      T+ G    PA+ +     +F  Q F F G+L +   S 
Sbjct: 606 LPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSH 665

Query: 661 TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720
                            P QC IC  + + ++AL  H RTH+GERP+ CKIC   FT K 
Sbjct: 666 LG-------------ISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKA 712

Query: 721 NLKTH 725
           N + H
Sbjct: 713 NCERH 717



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 47/191 (24%), Positives = 66/191 (34%), Gaps = 63/191 (32%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C +C    A K+AL  H R+H+ ERP++C +C    +   N ++HL    LK     +  
Sbjct: 673  CNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDI-- 730

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
                    +     +SS+A  +                       V     P TV     
Sbjct: 731  --------EKNIEYVSSSAAEL-----------------------VDAFCAPDTV----- 754

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERT---------HTGEKPFGCTICGRA 1149
                            C+ CG+      AL+IH RT         H G KPF C  C  A
Sbjct: 755  ----------------CRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAA 798

Query: 1150 FTTKGNLKVHM 1160
            F  K N   H+
Sbjct: 799  FAAKRNCIHHI 809



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 7/84 (8%)

Query: 681 CVICHRVLSCQSALKMHYRTH---TGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           C +C ++ + Q  L MH R H   TG     C ICG++ ++  +L  H  VH  + P   
Sbjct: 68  CPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERP--- 124

Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761
            + C +C + FT    + +H+++H
Sbjct: 125 -YKCTVCGQSFTTNGNMHRHMKIH 147



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 51/169 (30%), Positives = 69/169 (40%), Gaps = 20/169 (11%)

Query: 304  GPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLL 363
            G  EP       A+ A   P PAP  +      P++ +     APG+  G AP     L 
Sbjct: 1471 GRQEPKDEKGDGASTAEEGPQPAPEQEE---KPPETPAEVVESAPGA--GEAPA--EKLA 1523

Query: 364  PQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCR 423
             +T       P+   S A   ++        K    K P     +  AS  D   K  C 
Sbjct: 1524 EETEG-----PSDGESAAEKRSS-------EKSDDDKKPKTDSPKSVASKADKR-KKVCS 1570

Query: 424  FCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKE 472
             C K F S   L  H+RSHTGERP+KC  C   F+ K +L  H + H++
Sbjct: 1571 VCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQK 1619



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 96/416 (23%), Positives = 142/416 (34%), Gaps = 92/416 (22%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTG-----ERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           C  C K F    +L +H ++H       E+P    + G+    KG L +   +H +    
Sbjct: 318 CDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTK---- 373

Query: 477 IQMNPYPVPEYL--DN-----------VPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVP 523
             + P P  E L  DN           +P   G    +SL P +  +    S  VLP   
Sbjct: 374 -DVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASLG-GSLTVLPATK 431

Query: 524 TSVG-LQLPPTVPGAHGYADSPSATP--------------------ASRSPQRPSPASSE 562
            S+  L L P   G     DS                         AS  PQ   P  S+
Sbjct: 432 DSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPFSK 491

Query: 563 C--ASLSPGLNHVESGVSATAESPQSLLGG---PPLTKAEPVSLPC-------------- 603
              A L     H+         +P++++     PPL  A+  S  C              
Sbjct: 492 APAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISPSLPPPPLKLLK 551

Query: 604 ------TNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQ 657
                 +NA    +  G Q  AA T +         PG P +  Q +       LL    
Sbjct: 552 GSVEAASNAHLLQSKSGTQPHAA-TRLSLQQPRAELPGQPEMKTQLEQDSIIEALLP--- 607

Query: 658 TSETSKLQQLVENIDKK--MTDPN------------QCVICHRVLSCQSALKMHYRTHTG 703
            S  +K++Q +   + K  MT P              C  C++V +    L+ H R+H G
Sbjct: 608 LSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLG 667

Query: 704 ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIR 759
             P++C IC      K  L  H   H  + P    + C IC   FT     ++H+R
Sbjct: 668 ISPYQCNICDYIAADKAALIRHLRTHSGERP----YICKICHYPFTVKANCERHLR 719



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 22/45 (48%), Positives = 27/45 (60%)

Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVH 1159
            C  C + F  AS+LQ H  THTG+KPF C  C   F+TK N + H
Sbjct: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERH 1292



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%)

Query: 1080 LPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHN----CQSCGKTFSSASALQIHERTH 1135
            LP  ++     +   G   A M AP  ++TP        C+ C + F+ +  L+ H R+H
Sbjct: 606  LPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSH 665

Query: 1136 TGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
             G  P+ C IC      K  L  H+ TH
Sbjct: 666  LGISPYQCNICDYIAADKAALIRHLRTH 693



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 19/48 (39%), Positives = 27/48 (56%)

Query: 1113 HNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHM 1160
            + C  C    +  +AL  H RTH+GE+P+ C IC   FT K N + H+
Sbjct: 671  YQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHL 718



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 31/133 (23%), Positives = 53/133 (39%), Gaps = 11/133 (8%)

Query: 1081 PAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTH---TG 1137
            P G++ P+ P    GP          +     +NC  C K  ++   L +H R H   TG
Sbjct: 37   PQGIKSPSKPP---GPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTG 93

Query: 1138 EKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQ 1197
                 C+ICG++ ++  +L  HM  H        R  + +V        G+  +  ++ +
Sbjct: 94   GADHSCSICGKSLSSASSLDRHMLVH-----SGERPYKCTVCGQSFTTNGNMHRHMKIHE 148

Query: 1198 KDLAARAMNVDPS 1210
            KD  +      PS
Sbjct: 149  KDPNSATATAPPS 161



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 54/224 (24%), Positives = 76/224 (33%), Gaps = 67/224 (29%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTM----GNLKQHLLTHRLKELPS 1034
            C VC K F CK  LE H  +H+ + P  C +C   C T     G L+ + L H  K+LP 
Sbjct: 210  CPVCFKEFVCKYGLETHMETHS-DNPLRCDIC---CVTFRTHRGLLRHNALVH--KQLPR 263

Query: 1035 QLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGV---------- 1084
                  F                                +   P +PAG           
Sbjct: 264  DAMGRPF--------------------------------IQNNPSIPAGFHDLGFTDFSC 291

Query: 1085 -QVPAGPQTVMGPGLAPMLAPPPRRTPKQHN--CQSCGKTFSSASALQIHERTHTG---- 1137
             + P   Q      L   ++       +QH   C +C K F    +L +H++TH      
Sbjct: 292  RKFPRISQAWCETNLRRCIS-------EQHRFVCDTCDKAFPMLCSLALHKQTHVAADQG 344

Query: 1138 -EKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVEN 1180
             EKP    + G A   KG L +    H  +  PA     L  +N
Sbjct: 345  QEKPQATPLPGDALDQKGFLALLGLQHTKDVRPAPAEEPLPDDN 388



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

Query: 670 NIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTT-KGNLKTHFGV 728
           +++KK  +   C +C +   C+  L+ H  TH+ + P +C IC   F T +G L+ +  V
Sbjct: 199 DLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALV 257

Query: 729 HRAKP 733
           H+  P
Sbjct: 258 HKQLP 262



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 43/161 (26%), Positives = 63/161 (39%), Gaps = 26/161 (16%)

Query: 975  PSTVCGVCGKPFACKSALEIHYRS---------HTKERPFVCALCRRGCSTMGNLKQHLL 1025
            P TVC +CG+      AL IH R+         H   +PF C  C    +   N   H+L
Sbjct: 751  PDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHIL 810

Query: 1026 THRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGK---AMALGEGPPLPA 1082
               L  +P Q  + ++ L      P+   +A       E +G G+     ALG+  PL A
Sbjct: 811  KQHL-HVPEQDIE-SYVLAADGLGPAEAPAA-------EASGRGEDSGCAALGDCKPLTA 861

Query: 1083 GVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFS 1123
             ++   G    +  G  P   PPP  + K     S    F+
Sbjct: 862  FLEPQNG---FLHRG--PTQPPPPHVSIKLEPASSFAVDFN 897



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 59/260 (22%), Positives = 88/260 (33%), Gaps = 49/260 (18%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGE---------RPFKCNICGNRFSTKGNLKVHFQRHKE 472
           CR C +      AL+IH+R+H G          +PF+C  C   F+ K N   H  +   
Sbjct: 755 CRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHL 814

Query: 473 KYPHIQMNPYPVPE---YLDNVPTCSGIPYG-----MSLPPEKPVTTWLDSKPVLPTVPT 524
             P   +  Y +          P       G      +L   KP+T +L+        P 
Sbjct: 815 HVPEQDIESYVLAADGLGPAEAPAAEASGRGEDSGCAALGDCKPLTAFLE--------PQ 866

Query: 525 SVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAE-- 582
           +  L   PT P            P      +  PASS     +  L+  + G++      
Sbjct: 867 NGFLHRGPTQP------------PPPHVSIKLEPASSFAVDFNEPLDFSQKGLALVQVKQ 914

Query: 583 ------SPQSLLGGPPLTKAEPVSLPC-TNARAGDAPVGAQASAAPTSVDGAPTSLGSPG 635
                 SP SL+  P     EP+ L    N R GD  +   + A     +   +   SP 
Sbjct: 915 ENISFLSPSSLV--PYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPEEEAGSSEQPSP- 971

Query: 636 LPAVSEQFKAQFPFGGLLDS 655
            PA            G+L+S
Sbjct: 972 CPAPGPSLPVTLGPSGILES 991



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 22/66 (33%), Positives = 28/66 (42%), Gaps = 9/66 (13%)

Query: 669 ENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGE---------RPFKCKICGRAFTTK 719
           E +D        C +C   L    AL++H RTH G          +PF+CK C  AF  K
Sbjct: 743 ELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAK 802

Query: 720 GNLKTH 725
            N   H
Sbjct: 803 RNCIHH 808



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 1/69 (1%)

Query: 695 KMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVL 754
           + +  T   +  + C +C +  TT+  L  H   H         HSC IC K  ++A  L
Sbjct: 54  RRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTG-GADHSCSICGKSLSSASSL 112

Query: 755 QQHIRMHMG 763
            +H+ +H G
Sbjct: 113 DRHMLVHSG 121



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSH---TGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           + C  C K+  +   L +H+R H   TG     C+ICG   S+  +L  H   H  + P+
Sbjct: 66  YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 17/49 (34%), Positives = 22/49 (44%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
            C  C + FA    L  H RSH    P+ C +C    +    L +HL TH
Sbjct: 645  CRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTH 693



 Score = 35.0 bits (79), Expect = 0.47
 Identities = 37/163 (22%), Positives = 61/163 (37%), Gaps = 32/163 (19%)

Query: 14   SDEELLPPDGAPEHAAPGEGAE---------------DADSGPESRSGGEETSVCEKCCA 58
            ++E     DGA E A+  +  +               D ++G    +  E+   C+ C  
Sbjct: 1396 TEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGK 1455

Query: 59   EFFKWADFLEHQRSCTKLPPV------LIVHEDAPAPPPEDFPEPSPASSPSERAES--- 109
             F        H+++  +  P           E+ P P PE   E  P  +P+E  ES   
Sbjct: 1456 SFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQ--EEKPPETPAEVVESAPG 1513

Query: 110  --EAAEEAGAEGAEG----EARPVEKEAEPMDAEPAGDTRAPR 146
              EA  E  AE  EG    E+   ++ +E  D +    T +P+
Sbjct: 1514 AGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPK 1556



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 16/57 (28%), Positives = 24/57 (42%), Gaps = 4/57 (7%)

Query: 707 FKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
           + C+ C + F   G L+ H   H    P    + C IC     +   L +H+R H G
Sbjct: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISP----YQCNICDYIAADKAALIRHLRTHSG 695


>gi|4507987 zinc finger protein 136 [Homo sapiens]
          Length = 540

 Score = 97.4 bits (241), Expect = 8e-20
 Identities = 63/192 (32%), Positives = 85/192 (44%), Gaps = 10/192 (5%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037
            C VCGKPF   S+ ++H R HT E+PF C  C +  S    L+ H  TH   K    +  
Sbjct: 254  CKVCGKPFHSLSSFQVHERIHTGEKPFKCKQCGKAFSCSPTLRIHERTHTGEKPYECKQC 313

Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097
               F+  PS      I +     +  +    GKA        +         P      G
Sbjct: 314  GKAFSYLPSLRLHERIHTGEKPFVCKQC---GKAFRSASTFQIHERTHTGEKPYECKECG 370

Query: 1098 LAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151
             A    P  RR   +H       C+ CGK F S S  +IHERTHTGEKP+ C  CG+AF 
Sbjct: 371  EAFSCIPSMRRHMIKHTGEGPYKCKVCGKPFHSLSPFRIHERTHTGEKPYVCKHCGKAFV 430

Query: 1152 TKGNLKVHMGTH 1163
            +  ++++H  TH
Sbjct: 431  SSTSIRIHERTH 442



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 62/200 (31%), Positives = 90/200 (45%), Gaps = 12/200 (6%)

Query: 978  VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037
            VC  CGK F   S  +IH R+HT E+P+ C  C    S + ++++H++ H   E P   +
Sbjct: 337  VCKQCGKAFRSASTFQIHERTHTGEKPYECKECGEAFSCIPSMRRHMIKHT-GEGP---Y 392

Query: 1038 DPNFALGPSQS-TPSLISSAAPTMIKMEVNGH-GKAMALGEGPPLPAGVQVPAGPQTVMG 1095
                   P  S +P  I     T  K  V  H GKA        +         P     
Sbjct: 393  KCKVCGKPFHSLSPFRIHERTHTGEKPYVCKHCGKAFVSSTSIRIHERTHTGEKPYECKQ 452

Query: 1096 PGLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149
             G A       R     H       C+ CGK F S+S+ ++HERTHTG+KP+ C  CG+A
Sbjct: 453  CGKAFSYLNSFRTHEMIHTGEKPFECKRCGKAFRSSSSFRLHERTHTGQKPYHCKECGKA 512

Query: 1150 FTTKGNLKVHMGTHMWNNAP 1169
            ++ + + + HM TH  +  P
Sbjct: 513  YSCRASFQRHMLTHAEDGPP 532



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 63/227 (27%), Positives = 97/227 (42%), Gaps = 33/227 (14%)

Query: 969  RERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH- 1027
            +E G+ P T    C KPF+   +   H   HT E+ + C  C +   ++  +++H++TH 
Sbjct: 133  QEYGEKPDTR-NQCWKPFSSHHSFRTHEIIHTGEKLYDCKECGKTFFSLKRIRRHIITHS 191

Query: 1028 -----------RLKELPSQL--------FDPNFALGPSQSTPSLISSAAPTMIKMEVNGH 1068
                       +  + PS+          +  +         + I+S    MIK   +G 
Sbjct: 192  GYTPYKCKVCGKAFDYPSRFRTHERSHTGEKPYECQECGKAFTCITSVRRHMIKHTGDGP 251

Query: 1069 GKAMALGEGPPLPAGVQVPAGPQTVMGP------GLAPMLAPPPR---RT---PKQHNCQ 1116
             K    G+     +  QV     T   P      G A   +P  R   RT    K + C+
Sbjct: 252  YKCKVCGKPFHSLSSFQVHERIHTGEKPFKCKQCGKAFSCSPTLRIHERTHTGEKPYECK 311

Query: 1117 SCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
             CGK FS   +L++HER HTGEKPF C  CG+AF +    ++H  TH
Sbjct: 312  QCGKAFSYLPSLRLHERIHTGEKPFVCKQCGKAFRSASTFQIHERTH 358



 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 34/86 (39%), Positives = 48/86 (55%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC   L++H RTHTGE+P++CK CG+AF+   +L+ H  +H  + P   
Sbjct: 279 PFKCKQCGKAFSCSPTLRIHERTHTGEKPYECKQCGKAFSYLPSLRLHERIHTGEKPF-- 336

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
              C  C K F +A   Q H R H G
Sbjct: 337 --VCKQCGKAFRSASTFQIHERTHTG 360



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C +C +     S+ ++H R HTGE+PFKCK CG+AF+    L+ H   H  + P   
Sbjct: 251 PYKCKVCGKPFHSLSSFQVHERIHTGEKPFKCKQCGKAFSCSPTLRIHERTHTGEKP--- 307

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+    L+ H R+H G
Sbjct: 308 -YECKQCGKAFSYLPSLRLHERIHTG 332



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C +C +     S  + H R+HTGE+P++C+ CG+AFT   +++ H   H    P   
Sbjct: 195 PYKCKVCGKAFDYPSRFRTHERSHTGEKPYECQECGKAFTCITSVRRHMIKHTGDGP--- 251

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C +C K F +    Q H R+H G
Sbjct: 252 -YKCKVCGKPFHSLSSFQVHERIHTG 276



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +     +++++H RTHTGE+P++CK CG+AF+   + +TH  +H  + P   
Sbjct: 419 PYVCKHCGKAFVSSTSIRIHERTHTGEKPYECKQCGKAFSYLNSFRTHEMIHTGEKPF-- 476

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
              C  C K F ++   + H R H G
Sbjct: 477 --ECKRCGKAFRSSSSFRLHERTHTG 500



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  +C ++++ H   HTG+ P+KCK+CG+ F +  + + H  +H  + P + 
Sbjct: 223 PYECQECGKAFTCITSVRRHMIKHTGDGPYKCKVCGKPFHSLSSFQVHERIHTGEKPFK- 281

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
              C  C K F+ +  L+ H R H G
Sbjct: 282 ---CKQCGKAFSCSPTLRIHERTHTG 304



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C +C +     S  ++H RTHTGE+P+ CK CG+AF +  +++ H   H  + P   
Sbjct: 391 PYKCKVCGKPFHSLSPFRIHERTHTGEKPYVCKHCGKAFVSSTSIRIHERTHTGEKP--- 447

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+     + H  +H G
Sbjct: 448 -YECKQCGKAFSYLNSFRTHEMIHTG 472



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 26/57 (45%), Positives = 36/57 (63%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F S S+ Q+H R HTGE+PFKC  CG  FS    L++H + H  + P+
Sbjct: 252 YKCKVCGKPFHSLSSFQVHERIHTGEKPFKCKQCGKAFSCSPTLRIHERTHTGEKPY 308



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C    SC  +++ H   HTGE P+KCK+CG+ F +    + H   H  + P   
Sbjct: 363 PYECKECGEAFSCIPSMRRHMIKHTGEGPYKCKVCGKPFHSLSPFRIHERTHTGEKP--- 419

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F ++  ++ H R H G
Sbjct: 420 -YVCKHCGKAFVSSTSIRIHERTHTG 444



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +     S  ++H RTHTGE+P++CK CG AF+   +++ H   H  + P   
Sbjct: 335 PFVCKQCGKAFRSASTFQIHERTHTGEKPYECKECGEAFSCIPSMRRHMIKHTGEGP--- 391

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C +C K F +    + H R H G
Sbjct: 392 -YKCKVCGKPFHSLSPFRIHERTHTG 416



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S   +L++H R HTGE+PF CK CG+AF +    + H   H  + P   
Sbjct: 307 PYECKQCGKAFSYLPSLRLHERIHTGEKPFVCKQCGKAFRSASTFQIHERTHTGEKP--- 363

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C + F+    +++H+  H G
Sbjct: 364 -YECKECGEAFSCIPSMRRHMIKHTG 388



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 4/84 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S  ++ + H   HTGE+PF+CK CG+AF +  + + H   H  + P   
Sbjct: 447 PYECKQCGKAFSYLNSFRTHEMIHTGEKPFECKRCGKAFRSSSSFRLHERTHTGQKP--- 503

Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761
            + C  C K ++     Q+H+  H
Sbjct: 504 -YHCKECGKAYSCRASFQRHMLTH 526



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 7/83 (8%)

Query: 399 GKP----PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICG 454
           GKP     +  V E   + E PF   KC+ C K F     L+IH R+HTGE+P++C  CG
Sbjct: 258 GKPFHSLSSFQVHERIHTGEKPF---KCKQCGKAFSCSPTLRIHERTHTGEKPYECKQCG 314

Query: 455 NRFSTKGNLKVHFQRHKEKYPHI 477
             FS   +L++H + H  + P +
Sbjct: 315 KAFSYLPSLRLHERIHTGEKPFV 337



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 28/75 (37%), Positives = 43/75 (57%), Gaps = 3/75 (4%)

Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKG 461
           P++ + E   + E PF    C+ C K F S S  QIH R+HTGE+P++C  CG  FS   
Sbjct: 321 PSLRLHERIHTGEKPFV---CKQCGKAFRSASTFQIHERTHTGEKPYECKECGEAFSCIP 377

Query: 462 NLKVHFQRHKEKYPH 476
           +++ H  +H  + P+
Sbjct: 378 SMRRHMIKHTGEGPY 392



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 4/83 (4%)

Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740
           C  C +       ++ H  TH+G  P+KCK+CG+AF      +TH   H  + P    + 
Sbjct: 170 CKECGKTFFSLKRIRRHIITHSGYTPYKCKVCGKAFDYPSRFRTHERSHTGEKP----YE 225

Query: 741 CPICQKKFTNAVVLQQHIRMHMG 763
           C  C K FT    +++H+  H G
Sbjct: 226 CQECGKAFTCITSVRRHMIKHTG 248



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 25/67 (37%), Positives = 40/67 (59%), Gaps = 3/67 (4%)

Query: 410 KASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQR 469
           K + E P+   KC+ C K F S S  +IH R+HTGE+P+ C  CG  F +  ++++H + 
Sbjct: 385 KHTGEGPY---KCKVCGKPFHSLSPFRIHERTHTGEKPYVCKHCGKAFVSSTSIRIHERT 441

Query: 470 HKEKYPH 476
           H  + P+
Sbjct: 442 HTGEKPY 448



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 3/64 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           + E PF   +C+ C K F S S+ ++H R+HTG++P+ C  CG  +S + + + H   H 
Sbjct: 471 TGEKPF---ECKRCGKAFRSSSSFRLHERTHTGQKPYHCKECGKAYSCRASFQRHMLTHA 527

Query: 472 EKYP 475
           E  P
Sbjct: 528 EDGP 531



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 3/75 (4%)

Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKG 461
           P + + E   + E P+   +C+ C K F    +L++H R HTGE+PF C  CG  F +  
Sbjct: 293 PTLRIHERTHTGEKPY---ECKQCGKAFSYLPSLRLHERIHTGEKPFVCKQCGKAFRSAS 349

Query: 462 NLKVHFQRHKEKYPH 476
             ++H + H  + P+
Sbjct: 350 TFQIHERTHTGEKPY 364



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 3/70 (4%)

Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465
           + E   + E P+    C+ C K F S ++++IH R+HTGE+P++C  CG  FS   + + 
Sbjct: 409 IHERTHTGEKPYV---CKHCGKAFVSSTSIRIHERTHTGEKPYECKQCGKAFSYLNSFRT 465

Query: 466 HFQRHKEKYP 475
           H   H  + P
Sbjct: 466 HEMIHTGEKP 475



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 21/57 (36%), Positives = 33/57 (57%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   S  + H RSHTGE+P++C  CG  F+   +++ H  +H    P+
Sbjct: 196 YKCKVCGKAFDYPSRFRTHERSHTGEKPYECQECGKAFTCITSVRRHMIKHTGDGPY 252



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 19/57 (33%), Positives = 33/57 (57%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734
           P +C  C +     S+ ++H RTHTG++P+ CK CG+A++ + + + H   H    P
Sbjct: 475 PFECKRCGKAFRSSSSFRLHERTHTGQKPYHCKECGKAYSCRASFQRHMLTHAEDGP 531



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 20/72 (27%), Positives = 39/72 (54%), Gaps = 3/72 (4%)

Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465
           + E   + E P+   +C+ C + F    +++ H+  HTGE P+KC +CG  F +    ++
Sbjct: 353 IHERTHTGEKPY---ECKECGEAFSCIPSMRRHMIKHTGEGPYKCKVCGKPFHSLSPFRI 409

Query: 466 HFQRHKEKYPHI 477
           H + H  + P++
Sbjct: 410 HERTHTGEKPYV 421



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 21/74 (28%), Positives = 40/74 (54%), Gaps = 3/74 (4%)

Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462
           ++ + E   + E P+   +C+ C K F   ++ + H   HTGE+PF+C  CG  F +  +
Sbjct: 434 SIRIHERTHTGEKPY---ECKQCGKAFSYLNSFRTHEMIHTGEKPFECKRCGKAFRSSSS 490

Query: 463 LKVHFQRHKEKYPH 476
            ++H + H  + P+
Sbjct: 491 FRLHERTHTGQKPY 504



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P      E   + E P+   +C+ C K F   ++++ H+  HTG+ P+KC +CG  F + 
Sbjct: 208 PSRFRTHERSHTGEKPY---ECQECGKAFTCITSVRRHMIKHTGDGPYKCKVCGKPFHSL 264

Query: 461 GNLKVHFQRHKEKYP 475
            + +VH + H  + P
Sbjct: 265 SSFQVHERIHTGEKP 279



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 684 CHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPI 743
           C +  S   + + H   HTGE+ + CK CG+ F +   ++ H   H    P    + C +
Sbjct: 145 CWKPFSSHHSFRTHEIIHTGEKLYDCKECGKTFFSLKRIRRHIITHSGYTP----YKCKV 200

Query: 744 CQKKFTNAVVLQQHIRMHMG 763
           C K F      + H R H G
Sbjct: 201 CGKAFDYPSRFRTHERSHTG 220



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 17/57 (29%), Positives = 30/57 (52%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           + C+ C K F S   ++ H+ +H+G  P+KC +CG  F      + H + H  + P+
Sbjct: 168 YDCKECGKTFFSLKRIRRHIITHSGYTPYKCKVCGKAFDYPSRFRTHERSHTGEKPY 224



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 26/107 (24%), Positives = 47/107 (43%), Gaps = 16/107 (14%)

Query: 669 ENIDKKMTDPNQC--VICHRVLSCQSALKMHYRTHTG----------ERPFKCKICGRAF 716
           +N+ KK+     C  ++   V   QS+L  H + H+G          E+P     C + F
Sbjct: 90  QNLSKKIPGVKLCESIVYGEVSMGQSSLNRHIKDHSGHEPKEYQEYGEKPDTRNQCWKPF 149

Query: 717 TTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
           ++  + +TH  +H  +      + C  C K F +   +++HI  H G
Sbjct: 150 SSHHSFRTHEIIHTGEK----LYDCKECGKTFFSLKRIRRHIITHSG 192



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 16/52 (30%), Positives = 24/52 (46%)

Query: 425 CAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           C K F S  + + H   HTGE+ + C  CG  F +   ++ H   H    P+
Sbjct: 145 CWKPFSSHHSFRTHEIIHTGEKLYDCKECGKTFFSLKRIRRHIITHSGYTPY 196


>gi|21687252 zinc finger protein 296 [Homo sapiens]
          Length = 475

 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 67/213 (31%), Positives = 88/213 (41%), Gaps = 31/213 (14%)

Query: 976  STVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQ 1035
            S  C VC K  +  S L++H RSHT ERP+ C  C   C+    L +H  THR     S 
Sbjct: 230  SPTCPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPYACAQSSKLNRHKKTHRQVPPQSP 289

Query: 1036 LFDPNFALGPSQSTPS-LISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQT-- 1092
            L         S + P   + +AAPT       G       G G    AGVQ P  P +  
Sbjct: 290  LMADTSQEQASAAPPEPAVHAAAPTSTLPCSGGE------GAGAAATAGVQEPGAPGSGA 343

Query: 1093 VMGPG--------------LAPMLAPPPRRTPKQ--------HNCQSCGKTFSSASALQI 1130
              GPG               A      P++ PK          +C+ CGK F+++S L +
Sbjct: 344  QAGPGGDTWGAITTEQRTDPANSQKASPKKMPKSGGKSRGPGGSCEFCGKHFTNSSNLTV 403

Query: 1131 HERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            H R+HTGE+P+ C  C  A      L  H   H
Sbjct: 404  HRRSHTGERPYTCEFCNYACAQSSKLNRHRRMH 436



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 96/413 (23%), Positives = 138/413 (33%), Gaps = 43/413 (10%)

Query: 89  PPPEDFPEPSPASSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPP 148
           P P+  P+ +P   P    E      AG  G E    P      PM A  A     PR P
Sbjct: 36  PEPDAQPQQAPRLGPFSPKE---VSSAGRFGGEPHHSP-----GPMPAGAALLALGPRNP 87

Query: 149 PAAPAPPTPAYG--APSTNVTLEALLSTKV-------AVAQFSQ----GARAAGGSGAGG 195
                P TP Y    P T+   + L   +        A+  F      G +   G   G 
Sbjct: 88  WTLWTPLTPNYPDRQPWTDKHPDLLTCGRCLQTFPLEAITAFMDHKKLGCQLFRGPSRGQ 147

Query: 196 GVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAP 255
           G     +  +       Q     +L    Q    +++ Q     P  +P    +    A 
Sbjct: 148 GSEREELKALSCLRCGKQFTVAWKLLRHAQWDHGLSIYQTESEAPE-APLLGLAEVAAAV 206

Query: 256 SQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPS 315
           S + G AA   S  A  + +    P  P   +     S  +    +  G    +    P 
Sbjct: 207 SAVVGPAAEAKSPRASGSGLTRRSPTCPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPY 266

Query: 316 AAPAPAA---------PAPAPAPQSAASSQPQSASTPP-----ALAPGSLLGAAPGLPSP 361
           A    +            P  +P  A +SQ Q+++ PP     A AP S L  + G  + 
Sbjct: 267 ACAQSSKLNRHKKTHRQVPPQSPLMADTSQEQASAAPPEPAVHAAAPTSTLPCSGGEGAG 326

Query: 362 LLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKH- 420
                + +GV  P    S A      D   A+   ++  P N     PK   +       
Sbjct: 327 A---AATAGVQEPGAPGSGAQAGPGGDTWGAITTEQRTDPANSQKASPKKMPKSGGKSRG 383

Query: 421 ---KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
               C FC K F + S L +H RSHTGERP+ C  C    +    L  H + H
Sbjct: 384 PGGSCEFCGKHFTNSSNLTVHRRSHTGERPYTCEFCNYACAQSSKLNRHRRMH 436



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 45/172 (26%), Positives = 68/172 (39%), Gaps = 15/172 (8%)

Query: 591 PPLTKAEPVS-LPCTNARAGDAPV--GAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQF 647
           P +  A P S LPC+      A    G Q   AP S  GA    G     A++ + +   
Sbjct: 306 PAVHAAAPTSTLPCSGGEGAGAAATAGVQEPGAPGS--GAQAGPGGDTWGAITTEQRTD- 362

Query: 648 PFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPF 707
                      S+ +  +++ ++  K       C  C +  +  S L +H R+HTGERP+
Sbjct: 363 --------PANSQKASPKKMPKSGGKSRGPGGSCEFCGKHFTNSSNLTVHRRSHTGERPY 414

Query: 708 KCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIR 759
            C+ C  A      L  H  +H    P   +  CP C   F     L +H+R
Sbjct: 415 TCEFCNYACAQSSKLNRHRRMH-GMTPGSTRFECPHCHVPFGLRATLDKHLR 465



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 42/158 (26%), Positives = 58/158 (36%), Gaps = 32/158 (20%)

Query: 893  SPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAA--------A 944
            SP ++++S  QA +  P          P + A      +P         AA        A
Sbjct: 288  SPLMADTSQEQASAAPPE---------PAVHAAAPTSTLPCSGGEGAGAAATAGVQEPGA 338

Query: 945  PGSGGAPGRAGI---------------KEEAPFSLLFLSRERGKCPSTVCGVCGKPFACK 989
            PGSG   G  G                 ++A    +  S  + + P   C  CGK F   
Sbjct: 339  PGSGAQAGPGGDTWGAITTEQRTDPANSQKASPKKMPKSGGKSRGPGGSCEFCGKHFTNS 398

Query: 990  SALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
            S L +H RSHT ERP+ C  C   C+    L +H   H
Sbjct: 399  SNLTVHRRSHTGERPYTCEFCNYACAQSSKLNRHRRMH 436



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 8/90 (8%)

Query: 1079 PLPAGVQVPAGPQTVMGPGLAPMLAPPPRR-----TPKQHNCQSCGKTFSSASALQIHER 1133
            PL    +V A    V+GP      A  PR      T +   C  C KT SS S L++H R
Sbjct: 195  PLLGLAEVAAAVSAVVGPAAE---AKSPRASGSGLTRRSPTCPVCKKTLSSFSNLKVHMR 251

Query: 1134 THTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            +HTGE+P+ C  C  A      L  H  TH
Sbjct: 252  SHTGERPYACDQCPYACAQSSKLNRHKKTH 281



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 24/54 (44%), Positives = 29/54 (53%)

Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734
           C +C + LS  S LK+H R+HTGERP+ C  C  A      L  H   HR  PP
Sbjct: 233 CPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPYACAQSSKLNRHKKTHRQVPP 286



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 42/145 (28%), Positives = 61/145 (42%), Gaps = 8/145 (5%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481
           C  C K   S S L++H+RSHTGERP+ C+ C    +    L  H + H++  P   +  
Sbjct: 233 CPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPYACAQSSKLNRHKKTHRQVPPQSPLMA 292

Query: 482 YPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYA 541
               E        S  P   ++    P +T   S         + G+Q  P  PG+   A
Sbjct: 293 DTSQE------QASAAPPEPAVHAAAPTSTLPCSGGEGAGAAATAGVQ-EPGAPGSGAQA 345

Query: 542 DSPSAT-PASRSPQRPSPASSECAS 565
                T  A  + QR  PA+S+ AS
Sbjct: 346 GPGGDTWGAITTEQRTDPANSQKAS 370



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 10/81 (12%)

Query: 709 CKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMH------M 762
           C+ CG+ FT   NL  H   H  + P    ++C  C      +  L +H RMH       
Sbjct: 388 CEFCGKHFTNSSNLTVHRRSHTGERP----YTCEFCNYACAQSSKLNRHRRMHGMTPGST 443

Query: 763 GGQIPNTPLPEGFQDAMDSEL 783
             + P+  +P G +  +D  L
Sbjct: 444 RFECPHCHVPFGLRATLDKHL 464


>gi|193083160 zinc finger protein 441 [Homo sapiens]
          Length = 693

 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 62/188 (32%), Positives = 85/188 (45%), Gaps = 24/188 (12%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F C + L+IH R HT ERP+ C  C +   +   ++ H  TH   E P +   
Sbjct: 421  CKQCGKAFICCTYLQIHERIHTGERPYKCKQCGKAFRSSNYIRVHEKTHT-GEKPYECKQ 479

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
               AL       S + S    MI    +G  K    G+    P+  +      T   P  
Sbjct: 480  CGKAL-------SHLKSFQRHMIMHTGDGPHKCKICGKSFDSPSSFRRHERIHTGERP-- 530

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                          + C+ CGK F S+S +Q+HERTHTGEKP+GC  CG+A +   + + 
Sbjct: 531  --------------YKCKLCGKGFRSSSYIQLHERTHTGEKPYGCQQCGKALSDLSSFRR 576

Query: 1159 HMGTHMWN 1166
            HM TH  N
Sbjct: 577  HMITHTGN 584



 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 64/185 (34%), Positives = 80/185 (43%), Gaps = 24/185 (12%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C +CGK F   S+   H R HT ERP+ C LC +G  +   ++ H  TH   E P     
Sbjct: 505  CKICGKSFDSPSSFRRHERIHTGERPYKCKLCGKGFRSSSYIQLHERTHT-GEKPYGCQQ 563

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
               AL       S +SS    MI    NG  K    G+G   P+ VQ      T      
Sbjct: 564  CGKAL-------SDLSSFRRHMITHTGNGPHKCKICGKGFDYPSSVQRHERTHT------ 610

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                        K + C+ CGK FS +S L+IHER HTGEKP+ C  CG+ F        
Sbjct: 611  ----------GEKPYECKECGKAFSHSSYLRIHERVHTGEKPYKCKECGKPFHCPSAFHK 660

Query: 1159 HMGTH 1163
            H  TH
Sbjct: 661  HERTH 665



 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 53/189 (28%), Positives = 81/189 (42%), Gaps = 33/189 (17%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C +CGK F   S++  H R+HT E+P+ C  C +  S     ++H++TH           
Sbjct: 310  CKICGKGFLSPSSVRRHKRTHTGEKPYECKYCGKAFSDCTGFRRHMITHT---------- 359

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
                 GP +      +  +P++ +     H      GE P            +   G   
Sbjct: 360  ---GDGPHKCKVCGKAFDSPSLCRRHETTH-----TGEKPY-----------KCECGKAF 400

Query: 1099 APMLAPPPRRTP----KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKG 1154
            +         T     K + C+ CGK F   + LQIHER HTGE+P+ C  CG+AF +  
Sbjct: 401  SDFYYFRNHETTHTGEKPYKCKQCGKAFICCTYLQIHERIHTGERPYKCKQCGKAFRSSN 460

Query: 1155 NLKVHMGTH 1163
             ++VH  TH
Sbjct: 461  YIRVHEKTH 469



 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P QC  C +  SC    +++ RTHTGE+ ++CK CG+AF   G+ + H  VH    P   
Sbjct: 251 PYQCKQCGKAFSCSCYTQLYERTHTGEQSYECKQCGKAFYHLGSFQRHMIVHTGDGP--- 307

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            H C IC K F +   +++H R H G
Sbjct: 308 -HKCKICGKGFLSPSSVRRHKRTHTG 332



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 4/100 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P++C IC +     S+++ H RTHTGE+P++CK CG+AF+     + H   H    P   
Sbjct: 307 PHKCKICGKGFLSPSSVRRHKRTHTGEKPYECKYCGKAFSDCTGFRRHMITHTGDGP--- 363

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQD 777
            H C +C K F +  + ++H   H G +       + F D
Sbjct: 364 -HKCKVCGKAFDSPSLCRRHETTHTGEKPYKCECGKAFSD 402



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +   C + L++H R HTGERP+KCK CG+AF +   ++ H   H  + P   
Sbjct: 418 PYKCKQCGKAFICCTYLQIHERIHTGERPYKCKQCGKAFRSSNYIRVHEKTHTGEKP--- 474

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K  ++    Q+H+ MH G
Sbjct: 475 -YECKQCGKALSHLKSFQRHMIMHTG 499



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 62/212 (29%), Positives = 82/212 (38%), Gaps = 30/212 (14%)

Query: 957  KEEAPFSLL-----FLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCR 1011
            KE A FS L      ++   G  P  +C +CG  F   S   +  R+HT+E+P+    C 
Sbjct: 172  KECASFSSLENLQRHMAAHHGDGPR-ICKLCGNAFIWPSLFHMLRRTHTEEKPYEYEQCS 230

Query: 1012 RGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKA 1071
                   +  +H  TH   E P Q      A   S  T  L           E    GKA
Sbjct: 231  TAFPAYSSTLRHERTHS-GEKPYQCKQCGKAFSCSCYT-QLYERTHTGEQSYECKQCGKA 288

Query: 1072 MALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIH 1131
                        V    GP                      H C+ CGK F S S+++ H
Sbjct: 289  FYHLGSFQRHMIVHTGDGP----------------------HKCKICGKGFLSPSSVRRH 326

Query: 1132 ERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            +RTHTGEKP+ C  CG+AF+     + HM TH
Sbjct: 327  KRTHTGEKPYECKYCGKAFSDCTGFRRHMITH 358



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 24/110 (21%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P++C IC +     S+ + H R HTGERP+KCK+CG+ F +   ++ H   H  + P   
Sbjct: 502 PHKCKICGKSFDSPSSFRRHERIHTGERPYKCKLCGKGFRSSSYIQLHERTHTGEKPYGC 561

Query: 738 Q------------------------HSCPICQKKFTNAVVLQQHIRMHMG 763
           Q                        H C IC K F     +Q+H R H G
Sbjct: 562 QQCGKALSDLSSFRRHMITHTGNGPHKCKICGKGFDYPSSVQRHERTHTG 611



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 31/84 (36%), Positives = 46/84 (54%), Gaps = 4/84 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P++C IC +     S+++ H RTHTGE+P++CK CG+AF+    L+ H  VH  + P   
Sbjct: 586 PHKCKICGKGFDYPSSVQRHERTHTGEKPYECKECGKAFSHSSYLRIHERVHTGEKP--- 642

Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761
            + C  C K F       +H R H
Sbjct: 643 -YKCKECGKPFHCPSAFHKHERTH 665



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +     + +++H +THTGE+P++CK CG+A +   + + H  +H    P   
Sbjct: 446 PYKCKQCGKAFRSSNYIRVHEKTHTGEKPYECKQCGKALSHLKSFQRHMIMHTGDGP--- 502

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            H C IC K F +    ++H R+H G
Sbjct: 503 -HKCKICGKSFDSPSSFRRHERIHTG 527



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C + LS   + + H   HTG+ P KCKICG++F +  + + H  +H  + P   
Sbjct: 474 PYECKQCGKALSHLKSFQRHMIMHTGDGPHKCKICGKSFDSPSSFRRHERIHTGERP--- 530

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C +C K F ++  +Q H R H G
Sbjct: 531 -YKCKLCGKGFRSSSYIQLHERTHTG 555



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C + LS  S+ + H  THTG  P KCKICG+ F    +++ H   H  + P   
Sbjct: 558 PYGCQQCGKALSDLSSFRRHMITHTGNGPHKCKICGKGFDYPSSVQRHERTHTGEKP--- 614

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+++  L+ H R+H G
Sbjct: 615 -YECKECGKAFSHSSYLRIHERVHTG 639



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           HKC+ C K F S S+ + H R HTGERP+KC +CG  F +   +++H + H  + P+
Sbjct: 503 HKCKICGKSFDSPSSFRRHERIHTGERPYKCKLCGKGFRSSSYIQLHERTHTGEKPY 559



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           HKC+ C K F   S++Q H R+HTGE+P++C  CG  FS    L++H + H  + P+
Sbjct: 587 HKCKICGKGFDYPSSVQRHERTHTGEKPYECKECGKAFSHSSYLRIHERVHTGEKPY 643



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 48/184 (26%), Positives = 69/184 (37%), Gaps = 28/184 (15%)

Query: 982  CGKPFACKSALEIHYRSHTKERPFVCALCRR--GCSTMGNLKQHLLTHRLKELPSQLFDP 1039
            C   F   S+   H R+H+ E+P+ C  C +   CS    L +   T        Q    
Sbjct: 229  CSTAFPAYSSTLRHERTHSGEKPYQCKQCGKAFSCSCYTQLYERTHTGEQSYECKQCGKA 288

Query: 1040 NFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLA 1099
             + LG  Q            MI    +G  K    G+G   P+ V+      T       
Sbjct: 289  FYHLGSFQR----------HMIVHTGDGPHKCKICGKGFLSPSSVRRHKRTHT------- 331

Query: 1100 PMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVH 1159
                       K + C+ CGK FS  +  + H  THTG+ P  C +CG+AF +    + H
Sbjct: 332  ---------GEKPYECKYCGKAFSDCTGFRRHMITHTGDGPHKCKVCGKAFDSPSLCRRH 382

Query: 1160 MGTH 1163
              TH
Sbjct: 383  ETTH 386



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 25/57 (43%), Positives = 35/57 (61%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   + LQIH R HTGERP+KC  CG  F +   ++VH + H  + P+
Sbjct: 419 YKCKQCGKAFICCTYLQIHERIHTGERPYKCKQCGKAFRSSNYIRVHEKTHTGEKPY 475



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 24/57 (42%), Positives = 33/57 (57%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           HKC+ C K F S S+++ H R+HTGE+P++C  CG  FS     + H   H    PH
Sbjct: 308 HKCKICGKGFLSPSSVRRHKRTHTGEKPYECKYCGKAFSDCTGFRRHMITHTGDGPH 364



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 23/57 (40%), Positives = 32/57 (56%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F S S +Q+H R+HTGE+P+ C  CG   S   + + H   H    PH
Sbjct: 531 YKCKLCGKGFRSSSYIQLHERTHTGEKPYGCQQCGKALSDLSSFRRHMITHTGNGPH 587



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 4/84 (4%)

Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           +C  C +      + + H   HTG+ P KCKICG+ F +  +++ H   H  + P    +
Sbjct: 281 ECKQCGKAFYHLGSFQRHMIVHTGDGPHKCKICGKGFLSPSSVRRHKRTHTGEKP----Y 336

Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763
            C  C K F++    ++H+  H G
Sbjct: 337 ECKYCGKAFSDCTGFRRHMITHTG 360



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 5/86 (5%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S     + H  THTGE+P+KCK CG+AF     L+ H  +H  + P   
Sbjct: 391 PYKCE-CGKAFSDFYYFRNHETTHTGEKPYKCKQCGKAFICCTYLQIHERIHTGERP--- 446

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F ++  ++ H + H G
Sbjct: 447 -YKCKQCGKAFRSSNYIRVHEKTHTG 471



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P +V   E   + E P+   +C+ C K F   S L+IH R HTGE+P+KC  CG  F   
Sbjct: 599 PSSVQRHERTHTGEKPY---ECKECGKAFSHSSYLRIHERVHTGEKPYKCKECGKPFHCP 655

Query: 461 GNLKVHFQRHKEKYPH 476
                H + H  + P+
Sbjct: 656 SAFHKHERTHSMEKPY 671



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 4/84 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S  S L++H R HTGE+P+KCK CG+ F        H   H  + P   
Sbjct: 614 PYECKECGKAFSHSSYLRIHERVHTGEKPYKCKECGKPFHCPSAFHKHERTHSMEKP--- 670

Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761
            + C  C + F       +H   H
Sbjct: 671 -YKCKECGEAFHCISSFHKHEMTH 693



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 20/57 (35%), Positives = 33/57 (57%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F S + +++H ++HTGE+P++C  CG   S   + + H   H    PH
Sbjct: 447 YKCKQCGKAFRSSNYIRVHEKTHTGEKPYECKQCGKALSHLKSFQRHMIMHTGDGPH 503



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           HKC+ C K F S S  + H  +HTGE+P+KC  CG  FS     + H   H  + P+
Sbjct: 364 HKCKVCGKAFDSPSLCRRHETTHTGEKPYKCE-CGKAFSDFYYFRNHETTHTGEKPY 419



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 5/115 (4%)

Query: 652 LLDSMQTSETSKLQQLVENIDKKMTD-PNQCVICHRVLSCQSALKMHYRTHTGERPFKCK 710
           L D  + +  S L+ L  ++     D P  C +C       S   M  RTHT E+P++ +
Sbjct: 168 LYDCKECASFSSLENLQRHMAAHHGDGPRICKLCGNAFIWPSLFHMLRRTHTEEKPYEYE 227

Query: 711 ICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQ 765
            C  AF    +   H   H  + P    + C  C K F+ +   Q + R H G Q
Sbjct: 228 QCSTAFPAYSSTLRHERTHSGEKP----YQCKQCGKAFSCSCYTQLYERTHTGEQ 278



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P +V   +   + E P+   +C++C K F   +  + H+ +HTG+ P KC +CG  F + 
Sbjct: 320 PSSVRRHKRTHTGEKPY---ECKYCGKAFSDCTGFRRHMITHTGDGPHKCKVCGKAFDSP 376

Query: 461 GNLKVHFQRHKEKYPH 476
              + H   H  + P+
Sbjct: 377 SLCRRHETTHTGEKPY 392



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 19/49 (38%), Positives = 27/49 (55%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
            C  CGKPF C SA   H R+H+ E+P+ C  C      + +  +H +TH
Sbjct: 645  CKECGKPFHCPSAFHKHERTHSMEKPYKCKECGEAFHCISSFHKHEMTH 693



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 3/73 (4%)

Query: 404 VSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNL 463
           + V E   + E P+   +C+ C K      + Q H+  HTG+ P KC ICG  F +  + 
Sbjct: 462 IRVHEKTHTGEKPY---ECKQCGKALSHLKSFQRHMIMHTGDGPHKCKICGKSFDSPSSF 518

Query: 464 KVHFQRHKEKYPH 476
           + H + H  + P+
Sbjct: 519 RRHERIHTGERPY 531



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 3/65 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           S E P+   +C+ C K F      Q++ R+HTGE+ ++C  CG  F   G+ + H   H 
Sbjct: 247 SGEKPY---QCKQCGKAFSCSCYTQLYERTHTGEQSYECKQCGKAFYHLGSFQRHMIVHT 303

Query: 472 EKYPH 476
              PH
Sbjct: 304 GDGPH 308



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 19/57 (33%), Positives = 32/57 (56%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F    + Q H+  HTG+ P KC ICG  F +  +++ H + H  + P+
Sbjct: 280 YECKQCGKAFYHLGSFQRHMIVHTGDGPHKCKICGKGFLSPSSVRRHKRTHTGEKPY 336



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 19/51 (37%), Positives = 26/51 (50%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
           +KC+ C K F   SA   H R+H+ E+P+KC  CG  F    +   H   H
Sbjct: 643 YKCKECGKPFHCPSAFHKHERTHSMEKPYKCKECGEAFHCISSFHKHEMTH 693



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC  C K F      + H  +HTGE+P+KC  CG  F     L++H + H  + P+
Sbjct: 392 YKCE-CGKAFSDFYYFRNHETTHTGEKPYKCKQCGKAFICCTYLQIHERIHTGERPY 447



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 19/53 (35%), Positives = 27/53 (50%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKE 1031
            C  CGK F+  S L IH R HT E+P+ C  C +         +H  TH +++
Sbjct: 617  CKECGKAFSHSSYLRIHERVHTGEKPYKCKECGKPFHCPSAFHKHERTHSMEK 669



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 1/53 (1%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            K +    CG  FS     QIHER   G+K + C  C  +F++  NL+ HM  H
Sbjct: 139  KPYTHTQCGTAFSYQPCFQIHERPQHGKKLYDCKECA-SFSSLENLQRHMAAH 190



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 1/45 (2%)

Query: 1106 PRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAF 1150
            P+   K ++C+ C  +FSS   LQ H   H G+ P  C +CG AF
Sbjct: 162  PQHGKKLYDCKECA-SFSSLENLQRHMAAHHGDGPRICKLCGNAF 205



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 1/57 (1%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           + C+ CA  F S   LQ H+ +H G+ P  C +CGN F       +  + H E+ P+
Sbjct: 169 YDCKECAS-FSSLENLQRHMAAHHGDGPRICKLCGNAFIWPSLFHMLRRTHTEEKPY 224



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 15/46 (32%), Positives = 27/46 (58%)

Query: 425 CAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
           C+  F + S+   H R+H+GE+P++C  CG  FS     +++ + H
Sbjct: 229 CSTAFPAYSSTLRHERTHSGEKPYQCKQCGKAFSCSCYTQLYERTH 274



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 5/65 (7%)

Query: 684 CHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPI 743
           C    S Q   ++H R   G++ + CK C  +F++  NL+ H   H    P      C +
Sbjct: 146 CGTAFSYQPCFQIHERPQHGKKLYDCKECA-SFSSLENLQRHMAAHHGDGP----RICKL 200

Query: 744 CQKKF 748
           C   F
Sbjct: 201 CGNAF 205



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 1/53 (1%)

Query: 425 CAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
           C   F      QIH R   G++ + C  C + FS+  NL+ H   H    P I
Sbjct: 146 CGTAFSYQPCFQIHERPQHGKKLYDCKECAS-FSSLENLQRHMAAHHGDGPRI 197



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 14/55 (25%), Positives = 24/55 (43%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           C+ C   F   S   +  R+HT E+P++   C   F    +   H + H  + P+
Sbjct: 198 CKLCGNAFIWPSLFHMLRRTHTEEKPYEYEQCSTAFPAYSSTLRHERTHSGEKPY 252


>gi|47271376 zinc finger protein 615 [Homo sapiens]
          Length = 731

 Score = 94.4 bits (233), Expect = 7e-19
 Identities = 63/186 (33%), Positives = 84/186 (45%), Gaps = 26/186 (13%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK FA KS L  H R+HT E+P+VC  CR+G +   +L  H  TH   E P    D
Sbjct: 430  CNECGKGFALKSPLIRHQRTHTGEKPYVCTECRKGFTMKSDLIVHQRTHTA-EKPYICND 488

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGE-GPPLPAGVQVPAGPQTVMGPG 1097
                 G   +  S +      ++    +   K    GE G   PA +++    +T  G  
Sbjct: 489  ----CGKGFTVKSRL------IVHQRTHTGEKPYVCGECGKGFPAKIRLMGHQRTHTGE- 537

Query: 1098 LAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLK 1157
                         K + C  CGK F+  S L +H RTHTGEKP+ C+ CG+  T K  L 
Sbjct: 538  -------------KPYICNECGKGFTEKSHLNVHRRTHTGEKPYVCSECGKDLTGKSMLI 584

Query: 1158 VHMGTH 1163
             H  TH
Sbjct: 585  AHQRTH 590



 Score = 88.2 bits (217), Expect = 5e-17
 Identities = 60/187 (32%), Positives = 74/187 (39%), Gaps = 54/187 (28%)

Query: 978  VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH-RLKELPSQL 1036
            VC  CGK F   S    H R HT E+P VC++C +  S    L  H  TH  LK      
Sbjct: 205  VCSECGKAFLKLSQFIDHQRVHTGEKPHVCSMCGKAFSRKSRLMDHQRTHTELKHYECTE 264

Query: 1037 FDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP 1096
             D  F                  + K ++N H K                     T MG 
Sbjct: 265  CDKTF------------------LKKSQLNIHQK---------------------THMGG 285

Query: 1097 GLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNL 1156
                          K + C  CGK F     L  H+RTHTGEKP GC++CG+AF+TK +L
Sbjct: 286  --------------KPYTCSQCGKAFIKKCRLIYHQRTHTGEKPHGCSVCGKAFSTKFSL 331

Query: 1157 KVHMGTH 1163
              H  TH
Sbjct: 332  TTHQKTH 338



 Score = 87.8 bits (216), Expect = 6e-17
 Identities = 61/188 (32%), Positives = 82/188 (43%), Gaps = 28/188 (14%)

Query: 978  VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037
            +C  CGK F  K  L  H+R+HT E+PF+C  C +G +    LK  L+TH+      +L+
Sbjct: 345  ICSECGKGFIEKRRLTAHHRTHTGEKPFICNKCGKGFT----LKNSLITHQQTHTGEKLY 400

Query: 1038 D-PNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095
                   G S     ++     T  K  + N  GK  AL    PL    +   G      
Sbjct: 401  TCSECGKGFSMKHCLMVHQRTHTGEKPYKCNECGKGFALKS--PLIRHQRTHTG------ 452

Query: 1096 PGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGN 1155
                           K + C  C K F+  S L +H+RTHT EKP+ C  CG+ FT K  
Sbjct: 453  --------------EKPYVCTECRKGFTMKSDLIVHQRTHTAEKPYICNDCGKGFTVKSR 498

Query: 1156 LKVHMGTH 1163
            L VH  TH
Sbjct: 499  LIVHQRTH 506



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 58/186 (31%), Positives = 77/186 (41%), Gaps = 26/186 (13%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037
            C VCGK F+ K +L  H ++HT E+P++C+ C +G      L  H  TH   K       
Sbjct: 318  CSVCGKAFSTKFSLTTHQKTHTGEKPYICSECGKGFIEKRRLTAHHRTHTGEKPFICNKC 377

Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097
               F L  S  T     +        E          G+G  +   + V     T     
Sbjct: 378  GKGFTLKNSLITHQQTHTGEKLYTCSEC---------GKGFSMKHCLMVHQRTHT----- 423

Query: 1098 LAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLK 1157
                         K + C  CGK F+  S L  H+RTHTGEKP+ CT C + FT K +L 
Sbjct: 424  -----------GEKPYKCNECGKGFALKSPLIRHQRTHTGEKPYVCTECRKGFTMKSDLI 472

Query: 1158 VHMGTH 1163
            VH  TH
Sbjct: 473  VHQRTH 478



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 57/188 (30%), Positives = 79/188 (42%), Gaps = 28/188 (14%)

Query: 978  VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037
            +C  CGK F  KS L +H R+HT E+P+VC  C +G      L  H  TH          
Sbjct: 485  ICNDCGKGFTVKSRLIVHQRTHTGEKPYVCGECGKGFPAKIRLMGHQRTH---------- 534

Query: 1038 DPNFALGPSQSTPSLISSAAPTMI-KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP 1096
                    +   P + +        K  +N H +    GE P + +      G       
Sbjct: 535  --------TGEKPYICNECGKGFTEKSHLNVHRRTHT-GEKPYVCS----ECGKDLT--- 578

Query: 1097 GLAPMLAPPPRRT-PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGN 1155
            G + ++A     T  K + C  CGK F+  S L IH++THTGEKP+ C  C + F  K  
Sbjct: 579  GKSMLIAHQRTHTGEKPYICNECGKGFTMKSTLSIHQQTHTGEKPYKCNECDKTFRKKTC 638

Query: 1156 LKVHMGTH 1163
            L  H   H
Sbjct: 639  LIQHQRFH 646



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 57/214 (26%), Positives = 78/214 (36%), Gaps = 52/214 (24%)

Query: 978  VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037
            VCG CGK F  K  L  H R+HT E+P++C  C +G +   +L  H  TH          
Sbjct: 513  VCGECGKGFPAKIRLMGHQRTHTGEKPYICNECGKGFTEKSHLNVHRRTH---------- 562

Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097
                    +   P + S     +    +    +    GE P +        G    M   
Sbjct: 563  --------TGEKPYVCSECGKDLTGKSMLIAHQRTHTGEKPYICN----ECGKGFTMKST 610

Query: 1098 LAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHT--------------------- 1136
            L+  +        K + C  C KTF   + L  H+R HT                     
Sbjct: 611  LS--IHQQTHTGEKPYKCNECDKTFRKKTCLIQHQRFHTGKTSFACTECGKFSLRKNDLI 668

Query: 1137 -------GEKPFGCTICGRAFTTKGNLKVHMGTH 1163
                   GEKP+ C+ CG+AFTTK  L VH   H
Sbjct: 669  THQRIHTGEKPYKCSDCGKAFTTKSGLNVHQRKH 702



 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 34/86 (39%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C + L+ +S L  H RTHTGE+P+ C  CG+ FT K  L  H   H  + P   
Sbjct: 567 PYVCSECGKDLTGKSMLIAHQRTHTGEKPYICNECGKGFTMKSTLSIHQQTHTGEKP--- 623

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F     L QH R H G
Sbjct: 624 -YKCNECDKTFRKKTCLIQHQRFHTG 648



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 31/81 (38%), Positives = 43/81 (53%), Gaps = 4/81 (4%)

Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740
           C  C +    ++ L  H R HTGE+P+KC  CG+AFTTK  L  H   H  + P    + 
Sbjct: 654 CTECGKFSLRKNDLITHQRIHTGEKPYKCSDCGKAFTTKSGLNVHQRKHTGERP----YG 709

Query: 741 CPICQKKFTNAVVLQQHIRMH 761
           C  C K F +  +L +H R+H
Sbjct: 710 CSDCGKAFAHLSILVKHRRIH 730



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 33/86 (38%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +    +  L  H RTHTGE+P  C +CG+AF+TK +L TH   H  + P   
Sbjct: 287 PYTCSQCGKAFIKKCRLIYHQRTHTGEKPHGCSVCGKAFSTKFSLTTHQKTHTGEKP--- 343

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F     L  H R H G
Sbjct: 344 -YICSECGKGFIEKRRLTAHHRTHTG 368



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +  + +S L +H RTHT E+P+ C  CG+ FT K  L  H   H  + P   
Sbjct: 455 PYVCTECRKGFTMKSDLIVHQRTHTAEKPYICNDCGKGFTVKSRLIVHQRTHTGEKP--- 511

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F   + L  H R H G
Sbjct: 512 -YVCGECGKGFPAKIRLMGHQRTHTG 536



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 24/53 (45%), Positives = 33/53 (62%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            K + C  CGK F++ S L +H+R HTGE+P+GC+ CG+AF     L  H   H
Sbjct: 678  KPYKCSDCGKAFTTKSGLNVHQRKHTGERPYGCSDCGKAFAHLSILVKHRRIH 730



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 4/89 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P+ C +C +  S + +L  H +THTGE+P+ C  CG+ F  K  L  H   H  + P   
Sbjct: 315 PHGCSVCGKAFSTKFSLTTHQKTHTGEKPYICSECGKGFIEKRRLTAHHRTHTGEKPF-- 372

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQI 766
              C  C K FT    L  H + H G ++
Sbjct: 373 --ICNKCGKGFTLKNSLITHQQTHTGEKL 399



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 38/125 (30%), Positives = 54/125 (43%), Gaps = 9/125 (7%)

Query: 641 EQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRT 700
           +QF  +  F  +   +  S+  K QQ   NI+    + + C  C +     S    H R 
Sbjct: 171 KQFYTEMKFPAIAKPINKSQFIK-QQRTHNIE----NAHVCSECGKAFLKLSQFIDHQRV 225

Query: 701 HTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRM 760
           HTGE+P  C +CG+AF+ K  L  H   H         + C  C K F     L  H + 
Sbjct: 226 HTGEKPHVCSMCGKAFSRKSRLMDHQRTHTELK----HYECTECDKTFLKKSQLNIHQKT 281

Query: 761 HMGGQ 765
           HMGG+
Sbjct: 282 HMGGK 286



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 4/84 (4%)

Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           +C  C +    +S L +H +TH G +P+ C  CG+AF  K  L  H   H  + P    H
Sbjct: 261 ECTECDKTFLKKSQLNIHQKTHMGGKPYTCSQCGKAFIKKCRLIYHQRTHTGEKP----H 316

Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763
            C +C K F+    L  H + H G
Sbjct: 317 GCSVCGKAFSTKFSLTTHQKTHTG 340



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 31/81 (38%), Positives = 40/81 (49%), Gaps = 4/81 (4%)

Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740
           C  C +  S +  L +H RTHTGE+P+KC  CG+ F  K  L  H   H  + P    + 
Sbjct: 402 CSECGKGFSMKHCLMVHQRTHTGEKPYKCNECGKGFALKSPLIRHQRTHTGEKP----YV 457

Query: 741 CPICQKKFTNAVVLQQHIRMH 761
           C  C+K FT    L  H R H
Sbjct: 458 CTECRKGFTMKSDLIVHQRTH 478



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 31/86 (36%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +    +  L  H RTHTGE+P+ C  CG+ FT K +L  H   H  + P   
Sbjct: 511 PYVCGECGKGFPAKIRLMGHQRTHTGEKPYICNECGKGFTEKSHLNVHRRTHTGEKP--- 567

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K  T   +L  H R H G
Sbjct: 568 -YVCSECGKDLTGKSMLIAHQRTHTG 592



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 33/86 (38%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  + +S L  H RTHTGE+P+ C  C + FT K +L  H   H A+ P   
Sbjct: 427 PYKCNECGKGFALKSPLIRHQRTHTGEKPYVCTECRKGFTMKSDLIVHQRTHTAEKP--- 483

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K FT    L  H R H G
Sbjct: 484 -YICNDCGKGFTVKSRLIVHQRTHTG 508



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 25/51 (49%), Positives = 30/51 (58%)

Query: 1113 HNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            H C  CGK F   S    H+R HTGEKP  C++CG+AF+ K  L  H  TH
Sbjct: 204  HVCSECGKAFLKLSQFIDHQRVHTGEKPHVCSMCGKAFSRKSRLMDHQRTH 254



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 35/103 (33%), Positives = 45/103 (43%), Gaps = 4/103 (3%)

Query: 661 TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720
           T K   +V         P  C  C +  + +S L +H RTHTGE+P+ C  CG+ F  K 
Sbjct: 466 TMKSDLIVHQRTHTAEKPYICNDCGKGFTVKSRLIVHQRTHTGEKPYVCGECGKGFPAKI 525

Query: 721 NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
            L  H   H  + P    + C  C K FT    L  H R H G
Sbjct: 526 RLMGHQRTHTGEKP----YICNECGKGFTEKSHLNVHRRTHTG 564



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 26/54 (48%), Positives = 30/54 (55%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHM 1164
            K H C  CGK FS  S L  H+RTHT  K + CT C + F  K  L +H  THM
Sbjct: 230  KPHVCSMCGKAFSRKSRLMDHQRTHTELKHYECTECDKTFLKKSQLNIHQKTHM 283



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +  + +S L +H RTHTGE+P+ C  CG+  T K  L  H   H  + P   
Sbjct: 539 PYICNECGKGFTEKSHLNVHRRTHTGEKPYVCSECGKDLTGKSMLIAHQRTHTGEKP--- 595

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K FT    L  H + H G
Sbjct: 596 -YICNECGKGFTMKSTLSIHQQTHTG 620



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 23/58 (39%), Positives = 33/58 (56%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
           + C  C K F     L +H R+HTGE+P+KCN CG  F+ K  L  H + H  + P++
Sbjct: 400 YTCSECGKGFSMKHCLMVHQRTHTGEKPYKCNECGKGFALKSPLIRHQRTHTGEKPYV 457



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 24/58 (41%), Positives = 33/58 (56%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
           + C  C K F     L  H R+HTGE+P  C++CG  FSTK +L  H + H  + P+I
Sbjct: 288 YTCSQCGKAFIKKCRLIYHQRTHTGEKPHGCSVCGKAFSTKFSLTTHQKTHTGEKPYI 345



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +    ++ L  H R HTG+  F C  CG+    K +L TH  +H  + P   
Sbjct: 623 PYKCNECDKTFRKKTCLIQHQRFHTGKTSFACTECGKFSLRKNDLITHQRIHTGEKP--- 679

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K FT    L  H R H G
Sbjct: 680 -YKCSDCGKAFTTKSGLNVHQRKHTG 704



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 23/56 (41%), Positives = 33/56 (58%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
           C  C K F +   L  H R+HTGE+P+ CN CG  F+ K +L VH + H  + P++
Sbjct: 514 CGECGKGFPAKIRLMGHQRTHTGEKPYICNECGKGFTEKSHLNVHRRTHTGEKPYV 569



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 3/74 (4%)

Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462
           +++V     + E P+    C  C K     S L  H R+HTGE+P+ CN CG  F+ K  
Sbjct: 554 HLNVHRRTHTGEKPYV---CSECGKDLTGKSMLIAHQRTHTGEKPYICNECGKGFTMKST 610

Query: 463 LKVHFQRHKEKYPH 476
           L +H Q H  + P+
Sbjct: 611 LSIHQQTHTGEKPY 624



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 22/58 (37%), Positives = 31/58 (53%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
           H C  C K F +  +L  H ++HTGE+P+ C+ CG  F  K  L  H + H  + P I
Sbjct: 316 HGCSVCGKAFSTKFSLTTHQKTHTGEKPYICSECGKGFIEKRRLTAHHRTHTGEKPFI 373



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 23/55 (41%), Positives = 32/55 (58%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           C  C K     + L  H R HTGE+P+KC+ CG  F+TK  L VH ++H  + P+
Sbjct: 654 CTECGKFSLRKNDLITHQRIHTGEKPYKCSDCGKAFTTKSGLNVHQRKHTGERPY 708



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 24/58 (41%), Positives = 33/58 (56%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
           +KC  C K F   S L  H R+HTGE+P+ C  C   F+ K +L VH + H  + P+I
Sbjct: 428 YKCNECGKGFALKSPLIRHQRTHTGEKPYVCTECRKGFTMKSDLIVHQRTHTAEKPYI 485



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 23/56 (41%), Positives = 32/56 (57%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
           C  C K F   S L +H R+HT E+P+ CN CG  F+ K  L VH + H  + P++
Sbjct: 458 CTECRKGFTMKSDLIVHQRTHTAEKPYICNDCGKGFTVKSRLIVHQRTHTGEKPYV 513



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P+ C +C +  S +S L  H RTHT  + ++C  C + F  K  L  H   H    P   
Sbjct: 231 PHVCSMCGKAFSRKSRLMDHQRTHTELKHYECTECDKTFLKKSQLNIHQKTHMGGKP--- 287

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            ++C  C K F     L  H R H G
Sbjct: 288 -YTCSQCGKAFIKKCRLIYHQRTHTG 312



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 6/110 (5%)

Query: 370 GVIFPNPLVSIAATANALDPLSALMKHRKG--KPPNVSVFEPKASAEDPFFKHKCRFCAK 427
           G    +PL+    T     P     + RKG     ++ V +   +AE P+    C  C K
Sbjct: 436 GFALKSPLIRHQRTHTGEKPY-VCTECRKGFTMKSDLIVHQRTHTAEKPYI---CNDCGK 491

Query: 428 VFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
            F   S L +H R+HTGE+P+ C  CG  F  K  L  H + H  + P+I
Sbjct: 492 GFTVKSRLIVHQRTHTGEKPYVCGECGKGFPAKIRLMGHQRTHTGEKPYI 541



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +  + +++L  H +THTGE+ + C  CG+ F+ K  L  H   H  + P   
Sbjct: 371 PFICNKCGKGFTLKNSLITHQQTHTGEKLYTCSECGKGFSMKHCLMVHQRTHTGEKP--- 427

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F     L +H R H G
Sbjct: 428 -YKCNECGKGFALKSPLIRHQRTHTG 452



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 22/53 (41%), Positives = 30/53 (56%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHR 730
           P +C  C +  + +S L +H R HTGERP+ C  CG+AF     L  H  +HR
Sbjct: 679 PYKCSDCGKAFTTKSGLNVHQRKHTGERPYGCSDCGKAFAHLSILVKHRRIHR 731



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 22/52 (42%), Positives = 30/52 (57%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           +KC  C K F + S L +H R HTGERP+ C+ CG  F+    L  H + H+
Sbjct: 680 YKCSDCGKAFTTKSGLNVHQRKHTGERPYGCSDCGKAFAHLSILVKHRRIHR 731



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 28/73 (38%), Positives = 34/73 (46%)

Query: 400 KPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFST 459
           KP N S F  +    +    H C  C K F   S    H R HTGE+P  C++CG  FS 
Sbjct: 184 KPINKSQFIKQQRTHNIENAHVCSECGKAFLKLSQFIDHQRVHTGEKPHVCSMCGKAFSR 243

Query: 460 KGNLKVHFQRHKE 472
           K  L  H + H E
Sbjct: 244 KSRLMDHQRTHTE 256



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 5/82 (6%)

Query: 398 KGKPPNVSVF--EPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGN 455
           KG P  + +   +   + E P+    C  C K F   S L +H R+HTGE+P+ C+ CG 
Sbjct: 519 KGFPAKIRLMGHQRTHTGEKPYI---CNECGKGFTEKSHLNVHRRTHTGEKPYVCSECGK 575

Query: 456 RFSTKGNLKVHFQRHKEKYPHI 477
             + K  L  H + H  + P+I
Sbjct: 576 DLTGKSMLIAHQRTHTGEKPYI 597



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +  + +S L +H +THTGE+P+KC  C + F  K  L  H   H  K     
Sbjct: 595 PYICNECGKGFTMKSTLSIHQQTHTGEKPYKCNECDKTFRKKTCLIQHQRFHTGK----T 650

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
             +C  C K       L  H R+H G
Sbjct: 651 SFACTECGKFSLRKNDLITHQRIHTG 676



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 25/59 (42%), Positives = 31/59 (52%), Gaps = 3/59 (5%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
           + E P+    C  C K F     L  H R+HTGE+PF CN CG  F+ K +L  H Q H
Sbjct: 339 TGEKPYI---CSECGKGFIEKRRLTAHHRTHTGEKPFICNKCGKGFTLKNSLITHQQTH 394



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 25/62 (40%), Positives = 32/62 (51%), Gaps = 3/62 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           + E P+    C  C K F   S L IH ++HTGE+P+KCN C   F  K  L  H + H 
Sbjct: 591 TGEKPYI---CNECGKGFTMKSTLSIHQQTHTGEKPYKCNECDKTFRKKTCLIQHQRFHT 647

Query: 472 EK 473
            K
Sbjct: 648 GK 649



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 21/50 (42%), Positives = 28/50 (56%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR 1028
            C  CGK F  KS L +H R HT ERP+ C+ C +  + +  L +H   HR
Sbjct: 682  CSDCGKAFTTKSGLNVHQRKHTGERPYGCSDCGKAFAHLSILVKHRRIHR 731



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 21/57 (36%), Positives = 30/57 (52%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C  C K F   S L IH ++H G +P+ C+ CG  F  K  L  H + H  + PH
Sbjct: 260 YECTECDKTFLKKSQLNIHQKTHMGGKPYTCSQCGKAFIKKCRLIYHQRTHTGEKPH 316



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 24/65 (36%), Positives = 35/65 (53%), Gaps = 3/65 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           + E PF    C  C K F   ++L  H ++HTGE+ + C+ CG  FS K  L VH + H 
Sbjct: 367 TGEKPFI---CNKCGKGFTLKNSLITHQQTHTGEKLYTCSECGKGFSMKHCLMVHQRTHT 423

Query: 472 EKYPH 476
            + P+
Sbjct: 424 GEKPY 428



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 19/57 (33%), Positives = 26/57 (45%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           H C  C K F   S L  H R+HT  + ++C  C   F  K  L +H + H    P+
Sbjct: 232 HVCSMCGKAFSRKSRLMDHQRTHTELKHYECTECDKTFLKKSQLNIHQKTHMGGKPY 288



 Score = 38.5 bits (88), Expect = 0.042
 Identities = 19/52 (36%), Positives = 25/52 (48%)

Query: 976  STVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
            S  C  CGK    K+ L  H R HT E+P+ C+ C +  +T   L  H   H
Sbjct: 651  SFACTECGKFSLRKNDLITHQRIHTGEKPYKCSDCGKAFTTKSGLNVHQRKH 702


>gi|224548994 zinc finger protein 709 isoform b [Homo sapiens]
          Length = 609

 Score = 94.0 bits (232), Expect = 8e-19
 Identities = 60/194 (30%), Positives = 88/194 (45%), Gaps = 14/194 (7%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+C S+  +H R+HT E+P  C  C +  S   +++ H  TH   E P +   
Sbjct: 362  CKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRIHERTHT-GEKPYECKQ 420

Query: 1039 PNFALGPSQST---PSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095
               A   S S      + +   P     E    GKA +      +         P     
Sbjct: 421  CGKAFSCSSSFRMHERIHTGEKP----YECKQCGKAFSFSSSFRMHERTHTGEKPYECKQ 476

Query: 1096 PGLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149
             G A   +   R   + H       C+ CGK FS +S+++IHERTHTGEKP+ C  CG+A
Sbjct: 477  CGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKA 536

Query: 1150 FTTKGNLKVHMGTH 1163
            F+   ++++H  TH
Sbjct: 537  FSCSSSVRMHERTH 550



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 55/185 (29%), Positives = 81/185 (43%), Gaps = 24/185 (12%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK  +C ++   H R HT E+P+ C  C +  S   + ++H   H   E P    +
Sbjct: 250  CKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHT-GEKPYDCKE 308

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
               A          + S    MI    NG  K    G+    P+  Q+     T      
Sbjct: 309  CGKAF-------ISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHT------ 355

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                        K + C+ CGK FS +S+ ++HERTHTGEKP  C  CG+AF+   ++++
Sbjct: 356  ----------GEKPYECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRI 405

Query: 1159 HMGTH 1163
            H  TH
Sbjct: 406  HERTH 410



 Score = 87.8 bits (216), Expect = 6e-17
 Identities = 60/192 (31%), Positives = 88/192 (45%), Gaps = 10/192 (5%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+C S++ IH R+HT E+P+ C  C +  S   + + H   H   E P +   
Sbjct: 390  CKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHT-GEKPYECKQ 448

Query: 1039 PNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097
               A   S S+   +     T  K  E    GKA +      +         P      G
Sbjct: 449  CGKAF--SFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCG 506

Query: 1098 LAPMLAPPPR---RT---PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151
             A   +   R   RT    K + C+ CGK FS +S++++HERTHTG KP+ C  C +AF+
Sbjct: 507  KAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFS 566

Query: 1152 TKGNLKVHMGTH 1163
               + ++H  TH
Sbjct: 567  CSRSFRIHERTH 578



 Score = 87.8 bits (216), Expect = 6e-17
 Identities = 58/192 (30%), Positives = 81/192 (42%), Gaps = 10/192 (5%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+C S+  +H R HT E+P+ C  C +  S   + + H  TH   E P +   
Sbjct: 418  CKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHT-GEKPYECKQ 476

Query: 1039 PNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097
               A   S S    +     T  K  E    GKA +      +         P      G
Sbjct: 477  CGKAFSCSSSFR--MHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCG 534

Query: 1098 LAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151
             A   +   R   + H       C+ C K FS + + +IHERTHTGEKP+ C  CG+AF 
Sbjct: 535  KAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRSFRIHERTHTGEKPYACQQCGKAFK 594

Query: 1152 TKGNLKVHMGTH 1163
               + ++H   H
Sbjct: 595  CSRSFRIHERVH 606



 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 61/194 (31%), Positives = 82/194 (42%), Gaps = 14/194 (7%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+  S+   H R+H+ E+P+ C  C +        + H  TH   E P Q   
Sbjct: 194  CKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTH-TGEKPYQCKQ 252

Query: 1039 PNFALGPSQSTPS---LISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095
               AL    S  S   + +   P   K      GKA +          +     P     
Sbjct: 253  CGKALSCPTSFRSHERIHTGEKPYKCKK----CGKAFSFPSSFRKHERIHTGEKPYDCKE 308

Query: 1096 PGLAPMLAPPPRRTPKQH------NCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149
             G A +  P  RR    H       C+ CGK F   S+ QIHERTHTGEKP+ C  CG+A
Sbjct: 309  CGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKA 368

Query: 1150 FTTKGNLKVHMGTH 1163
            F+   + ++H  TH
Sbjct: 369  FSCSSSFRMHERTH 382



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 59/198 (29%), Positives = 85/198 (42%), Gaps = 16/198 (8%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+  S+ +IH R+HT E+P+ C  C +        + H+  H   E P +  +
Sbjct: 138  CKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRGHMRMHT-GEKPYKCKE 196

Query: 1039 PNFALGPSQSTPSLISSAAPTMI---KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095
                 G + S PS   +   T       E    GKA    +   +         P     
Sbjct: 197  ----CGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQ 252

Query: 1096 PGLAPMLAPPPRRT-------PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGR 1148
             G A +  P   R+        K + C+ CGK FS  S+ + HER HTGEKP+ C  CG+
Sbjct: 253  CGKA-LSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGK 311

Query: 1149 AFTTKGNLKVHMGTHMWN 1166
            AF +  + + HM  H  N
Sbjct: 312  AFISLPSYRRHMIMHTGN 329



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P++C  C +  SC S++++H RTHTGE+P++CK CG+AF+   + + H  +H  + P   
Sbjct: 387 PHECKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHTGEKP--- 443

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   + H R H G
Sbjct: 444 -YECKQCGKAFSFSSSFRMHERTHTG 468



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 32/86 (37%), Positives = 50/86 (58%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S+ +MH RTHTGE+P++CK CG+AF+   +++ H   H  + P   
Sbjct: 471 PYECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKP--- 527

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +  ++ H R H G
Sbjct: 528 -YECKQCGKAFSCSSSVRMHERTHTG 552



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S+ +MH RTHTGE+P +CK CG+AF+   +++ H   H  + P   
Sbjct: 359 PYECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRIHERTHTGEKP--- 415

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   + H R+H G
Sbjct: 416 -YECKQCGKAFSCSSSFRMHERIHTG 440



 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P QC  C + LSC ++ + H R HTGE+P+KCK CG+AF+   + + H  +H  + P   
Sbjct: 247 PYQCKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGEKP--- 303

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F +    ++H+ MH G
Sbjct: 304 -YDCKECGKAFISLPSYRRHMIMHTG 328



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 55/191 (28%), Positives = 78/191 (40%), Gaps = 36/191 (18%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+ +S+  IH R+HT E+P+ C  C +  S   + + H  TH   E P +  +
Sbjct: 110  CKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTH-TGEKPYECKE 168

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
               A                 +      GH + M  GE P      +     +T   P  
Sbjct: 169  CGKAF----------------IYHTTFRGHMR-MHTGEKP-----YKCKECGKTFSHPSS 206

Query: 1099 APMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTT 1152
                    R   + H+      C+ CGK F      QIHERTHTGEKP+ C  CG+A + 
Sbjct: 207  F-------RNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSC 259

Query: 1153 KGNLKVHMGTH 1163
              + + H   H
Sbjct: 260  PTSFRSHERIH 270



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 55/201 (27%), Positives = 76/201 (37%), Gaps = 46/201 (22%)

Query: 979  CGVCGKPFACKSALEIHYRSHTK----------ERPFVCALCRRGCSTMGNLKQHLLTHR 1028
            C VCGK + C S+L  H RSHT+          E+ + C  C +  S   + + H  TH 
Sbjct: 72   CSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHERTH- 130

Query: 1029 LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPA 1088
                                     +   P   K      GKA +      +        
Sbjct: 131  -------------------------TGEKPYKCKQ----CGKAFSWPSSFQIHERTHTGE 161

Query: 1089 GPQTVMGPGLAPMLAPPPRRTPKQH------NCQSCGKTFSSASALQIHERTHTGEKPFG 1142
             P      G A +     R   + H       C+ CGKTFS  S+ + HERTH+GEKP+ 
Sbjct: 162  KPYECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHPSSFRNHERTHSGEKPYE 221

Query: 1143 CTICGRAFTTKGNLKVHMGTH 1163
            C  CG+AF      ++H  TH
Sbjct: 222  CKQCGKAFRYYQTFQIHERTH 242



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S++++H RTHTGE+P++CK CG+AF+   +++ H   H    P   
Sbjct: 499 PYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKP--- 555

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   + H R H G
Sbjct: 556 -YECKQCDKAFSCSRSFRIHERTHTG 580



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +   C S+ ++H RTHTGE+P++CK CG+AF+   + + H   H  + P   
Sbjct: 331 PYKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKP--- 387

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            H C  C K F+ +  ++ H R H G
Sbjct: 388 -HECKQCGKAFSCSSSVRIHERTHTG 412



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S+ +MH R HTGE+P++CK CG+AF+   + + H   H  + P   
Sbjct: 415 PYECKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHTGEKP--- 471

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   + H R H G
Sbjct: 472 -YECKQCGKAFSCSSSFRMHERTHTG 496



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S  S+ +MH RTHTGE+P++CK CG+AF+   + + H   H  + P   
Sbjct: 443 PYECKQCGKAFSFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKP--- 499

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +  ++ H R H G
Sbjct: 500 -YECKQCGKAFSCSSSIRIHERTHTG 524



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 4/84 (4%)

Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           +C  C +  S +S+ ++H RTHTGE+P+KCK CG+AF+   + + H   H  + P    +
Sbjct: 109 ECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTHTGEKP----Y 164

Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763
            C  C K F      + H+RMH G
Sbjct: 165 ECKECGKAFIYHTTFRGHMRMHTG 188



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S+++MH RTHTG +P++CK C +AF+   + + H   H  + P   
Sbjct: 527 PYECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRSFRIHERTHTGEKP--- 583

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            ++C  C K F  +   + H R+H G
Sbjct: 584 -YACQQCGKAFKCSRSFRIHERVHSG 608



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S  S+ ++H RTHTGE+P++CK CG+AF      + H  +H  + P   
Sbjct: 135 PYKCKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRGHMRMHTGEKP--- 191

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F++    + H R H G
Sbjct: 192 -YKCKECGKTFSHPSSFRNHERTHSG 216



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +        ++H RTHTGE+P++CK CG+A +   + ++H  +H  + P   
Sbjct: 219 PYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSCPTSFRSHERIHTGEKP--- 275

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+     ++H R+H G
Sbjct: 276 -YKCKKCGKAFSFPSSFRKHERIHTG 300



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   S+ QIH R+HTGE+P++C  CG  FS   + ++H + H  + PH
Sbjct: 332 YKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPH 388



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S  S+ + H R HTGE+P+ CK CG+AF +  + + H  +H    P   
Sbjct: 275 PYKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGKAFISLPSYRRHMIMHTGNGP--- 331

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F      Q H R H G
Sbjct: 332 -YKCKECGKAFDCPSSFQIHERTHTG 356



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +     +  + H R HTGE+P+KCK CG+ F+   + + H   H  + P   
Sbjct: 163 PYECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHPSSFRNHERTHSGEKP--- 219

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F      Q H R H G
Sbjct: 220 -YECKQCGKAFRYYQTFQIHERTHTG 244



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S  S+ + H RTH+GE+P++CK CG+AF      + H   H  + P   
Sbjct: 191 PYKCKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKP--- 247

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K  +     + H R+H G
Sbjct: 248 -YQCKQCGKALSCPTSFRSHERIHTG 272



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 22/57 (38%), Positives = 37/57 (64%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           H+C+ C K F   S+++IH R+HTGE+P++C  CG  FS   + ++H + H  + P+
Sbjct: 388 HECKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHTGEKPY 444



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P +  + E   + E P+   +C+ C K F   S+ ++H R+HTGE+P +C  CG  FS  
Sbjct: 344 PSSFQIHERTHTGEKPY---ECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCS 400

Query: 461 GNLKVHFQRHKEKYPH 476
            ++++H + H  + P+
Sbjct: 401 SSVRIHERTHTGEKPY 416



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 50/181 (27%), Positives = 71/181 (39%), Gaps = 30/181 (16%)

Query: 962  FSLLFLSRER---GKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMG 1018
            FS  F   ER   G+ P   C  CGK F+C S+  +H R+HT E+P+ C  C +  S   
Sbjct: 455  FSSSFRMHERTHTGEKPYE-CKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSS 513

Query: 1019 NLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEG 1077
            +++ H  TH   E P +      A   S S    +     T +K  E     KA +    
Sbjct: 514  SIRIHERTHT-GEKPYECKQCGKAFSCSSSVR--MHERTHTGVKPYECKQCDKAFSCSRS 570

Query: 1078 PPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTG 1137
              +         P                      + CQ CGK F  + + +IHER H+G
Sbjct: 571  FRIHERTHTGEKP----------------------YACQQCGKAFKCSRSFRIHERVHSG 608

Query: 1138 E 1138
            E
Sbjct: 609  E 609



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 20/57 (35%), Positives = 37/57 (64%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F   S+ ++H R+HTGE+P++C  CG  FS   ++++H + H  + P+
Sbjct: 472 YECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPY 528



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 21/57 (36%), Positives = 37/57 (64%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F   S+++IH R+HTGE+P++C  CG  FS   ++++H + H    P+
Sbjct: 500 YECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKPY 556



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 14/96 (14%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHT----------GERPFKCKICGRAFTTKGNLKTHFG 727
           P +C +C +   C S+L  H R+HT          GE+ ++CK CG+ F+ + + + H  
Sbjct: 69  PYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHER 128

Query: 728 VHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
            H  + P    + C  C K F+     Q H R H G
Sbjct: 129 THTGEKP----YKCKQCGKAFSWPSSFQIHERTHTG 160



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 3/74 (4%)

Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462
           +V + E   + E P+   +C+ C K F   S+ ++H R HTGE+P++C  CG  FS   +
Sbjct: 402 SVRIHERTHTGEKPY---ECKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSS 458

Query: 463 LKVHFQRHKEKYPH 476
            ++H + H  + P+
Sbjct: 459 FRMHERTHTGEKPY 472



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 22/57 (38%), Positives = 36/57 (63%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F   S+ +IH R+HTGE+P+KC  CG  FS   + ++H + H  + P+
Sbjct: 108 YECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTHTGEKPY 164



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 20/57 (35%), Positives = 36/57 (63%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F   S+ ++H R+HTGE+P++C  CG  FS   + ++H + H  + P+
Sbjct: 444 YECKQCGKAFSFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPY 500



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 3/71 (4%)

Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465
           + E   + E P+   KC+ C K F   S+ QIH R+HTGE+P++C  CG  F      + 
Sbjct: 125 IHERTHTGEKPY---KCKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRG 181

Query: 466 HFQRHKEKYPH 476
           H + H  + P+
Sbjct: 182 HMRMHTGEKPY 192



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P +  + E   + E P+   +C+ C K F   +  + H+R HTGE+P+KC  CG  FS  
Sbjct: 148 PSSFQIHERTHTGEKPY---ECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHP 204

Query: 461 GNLKVHFQRHKEKYPH 476
            + + H + H  + P+
Sbjct: 205 SSFRNHERTHSGEKPY 220



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +      + + H   HTG  P+KCK CG+AF    + + H   H  + P   
Sbjct: 303 PYDCKECGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKP--- 359

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   + H R H G
Sbjct: 360 -YECKQCGKAFSCSSSFRMHERTHTG 384



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 3/74 (4%)

Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462
           ++ + E   + E P+   +C+ C K F   S++++H R+HTG +P++C  C   FS   +
Sbjct: 514 SIRIHERTHTGEKPY---ECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRS 570

Query: 463 LKVHFQRHKEKYPH 476
            ++H + H  + P+
Sbjct: 571 FRIHERTHTGEKPY 584



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 19/57 (33%), Positives = 33/57 (57%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   S+ + H R+H+GE+P++C  CG  F      ++H + H  + P+
Sbjct: 192 YKCKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPY 248



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P +    E   S E P+   +C+ C K F      QIH R+HTGE+P++C  CG   S  
Sbjct: 204 PSSFRNHERTHSGEKPY---ECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSCP 260

Query: 461 GNLKVHFQRHKEKYPH 476
            + + H + H  + P+
Sbjct: 261 TSFRSHERIHTGEKPY 276



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 18/51 (35%), Positives = 30/51 (58%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
           ++C+ C K F    + +IH R+HTGE+P+ C  CG  F    + ++H + H
Sbjct: 556 YECKQCDKAFSCSRSFRIHERTHTGEKPYACQQCGKAFKCSRSFRIHERVH 606



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465
           + E   + E P+   +C+ C K     ++ + H R HTGE+P+KC  CG  FS   + + 
Sbjct: 237 IHERTHTGEKPY---QCKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRK 293

Query: 466 HFQRHKEKYPH 476
           H + H  + P+
Sbjct: 294 HERIHTGEKPY 304



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 20/57 (35%), Positives = 30/57 (52%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   S+ + H R HTGE+P+ C  CG  F +  + + H   H    P+
Sbjct: 276 YKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGKAFISLPSYRRHMIMHTGNGPY 332



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 10/67 (14%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHT----------GERPFKCNICGNRFSTKGNLKVHFQR 469
           ++C  C K +   S+L  H+RSHT          GE+ ++C  CG RFS + + ++H + 
Sbjct: 70  YECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHERT 129

Query: 470 HKEKYPH 476
           H  + P+
Sbjct: 130 HTGEKPY 136



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 10/63 (15%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHT----------GEKPFGCTICGRAFTTKGNLKVHM 1160
            K + C  CGK +   S+L  H R+HT          GEK + C  CG+ F+ + + ++H 
Sbjct: 68   KPYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHE 127

Query: 1161 GTH 1163
             TH
Sbjct: 128  RTH 130



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 18/57 (31%), Positives = 30/57 (52%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           + C+ C K F S  + + H+  HTG  P+KC  CG  F    + ++H + H  + P+
Sbjct: 304 YDCKECGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKPY 360



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 14/45 (31%), Positives = 26/45 (57%)

Query: 1119 GKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            G+T S     + +++T T  KP+ C++CG+ +    +L  HM +H
Sbjct: 48   GETISQTPNPKPNKKTFTRVKPYECSVCGKDYMCHSSLNRHMRSH 92



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 6/75 (8%)

Query: 695 KMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV------QHSCPICQKKF 748
           K + +T T  +P++C +CG+ +    +L  H   H               + C  C K+F
Sbjct: 58  KPNKKTFTRVKPYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRF 117

Query: 749 TNAVVLQQHIRMHMG 763
           +     + H R H G
Sbjct: 118 SFRSSFRIHERTHTG 132


>gi|22749235 zinc finger protein 709 isoform a [Homo sapiens]
          Length = 641

 Score = 94.0 bits (232), Expect = 8e-19
 Identities = 60/194 (30%), Positives = 88/194 (45%), Gaps = 14/194 (7%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+C S+  +H R+HT E+P  C  C +  S   +++ H  TH   E P +   
Sbjct: 394  CKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRIHERTHT-GEKPYECKQ 452

Query: 1039 PNFALGPSQST---PSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095
               A   S S      + +   P     E    GKA +      +         P     
Sbjct: 453  CGKAFSCSSSFRMHERIHTGEKP----YECKQCGKAFSFSSSFRMHERTHTGEKPYECKQ 508

Query: 1096 PGLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149
             G A   +   R   + H       C+ CGK FS +S+++IHERTHTGEKP+ C  CG+A
Sbjct: 509  CGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKA 568

Query: 1150 FTTKGNLKVHMGTH 1163
            F+   ++++H  TH
Sbjct: 569  FSCSSSVRMHERTH 582



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 55/185 (29%), Positives = 81/185 (43%), Gaps = 24/185 (12%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK  +C ++   H R HT E+P+ C  C +  S   + ++H   H   E P    +
Sbjct: 282  CKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHT-GEKPYDCKE 340

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
               A          + S    MI    NG  K    G+    P+  Q+     T      
Sbjct: 341  CGKAF-------ISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHT------ 387

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                        K + C+ CGK FS +S+ ++HERTHTGEKP  C  CG+AF+   ++++
Sbjct: 388  ----------GEKPYECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRI 437

Query: 1159 HMGTH 1163
            H  TH
Sbjct: 438  HERTH 442



 Score = 87.8 bits (216), Expect = 6e-17
 Identities = 60/192 (31%), Positives = 88/192 (45%), Gaps = 10/192 (5%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+C S++ IH R+HT E+P+ C  C +  S   + + H   H   E P +   
Sbjct: 422  CKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHT-GEKPYECKQ 480

Query: 1039 PNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097
               A   S S+   +     T  K  E    GKA +      +         P      G
Sbjct: 481  CGKAF--SFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCG 538

Query: 1098 LAPMLAPPPR---RT---PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151
             A   +   R   RT    K + C+ CGK FS +S++++HERTHTG KP+ C  C +AF+
Sbjct: 539  KAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFS 598

Query: 1152 TKGNLKVHMGTH 1163
               + ++H  TH
Sbjct: 599  CSRSFRIHERTH 610



 Score = 87.8 bits (216), Expect = 6e-17
 Identities = 58/192 (30%), Positives = 81/192 (42%), Gaps = 10/192 (5%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+C S+  +H R HT E+P+ C  C +  S   + + H  TH   E P +   
Sbjct: 450  CKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHT-GEKPYECKQ 508

Query: 1039 PNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097
               A   S S    +     T  K  E    GKA +      +         P      G
Sbjct: 509  CGKAFSCSSSFR--MHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCG 566

Query: 1098 LAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151
             A   +   R   + H       C+ C K FS + + +IHERTHTGEKP+ C  CG+AF 
Sbjct: 567  KAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRSFRIHERTHTGEKPYACQQCGKAFK 626

Query: 1152 TKGNLKVHMGTH 1163
               + ++H   H
Sbjct: 627  CSRSFRIHERVH 638



 Score = 85.1 bits (209), Expect = 4e-16
 Identities = 61/194 (31%), Positives = 82/194 (42%), Gaps = 14/194 (7%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+  S+   H R+H+ E+P+ C  C +        + H  TH   E P Q   
Sbjct: 226  CKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTH-TGEKPYQCKQ 284

Query: 1039 PNFALGPSQSTPS---LISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095
               AL    S  S   + +   P   K      GKA +          +     P     
Sbjct: 285  CGKALSCPTSFRSHERIHTGEKPYKCKK----CGKAFSFPSSFRKHERIHTGEKPYDCKE 340

Query: 1096 PGLAPMLAPPPRRTPKQH------NCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149
             G A +  P  RR    H       C+ CGK F   S+ QIHERTHTGEKP+ C  CG+A
Sbjct: 341  CGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKA 400

Query: 1150 FTTKGNLKVHMGTH 1163
            F+   + ++H  TH
Sbjct: 401  FSCSSSFRMHERTH 414



 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 59/198 (29%), Positives = 85/198 (42%), Gaps = 16/198 (8%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+  S+ +IH R+HT E+P+ C  C +        + H+  H   E P +  +
Sbjct: 170  CKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRGHMRMHT-GEKPYKCKE 228

Query: 1039 PNFALGPSQSTPSLISSAAPTMI---KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095
                 G + S PS   +   T       E    GKA    +   +         P     
Sbjct: 229  ----CGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQ 284

Query: 1096 PGLAPMLAPPPRRT-------PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGR 1148
             G A +  P   R+        K + C+ CGK FS  S+ + HER HTGEKP+ C  CG+
Sbjct: 285  CGKA-LSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGK 343

Query: 1149 AFTTKGNLKVHMGTHMWN 1166
            AF +  + + HM  H  N
Sbjct: 344  AFISLPSYRRHMIMHTGN 361



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P++C  C +  SC S++++H RTHTGE+P++CK CG+AF+   + + H  +H  + P   
Sbjct: 419 PHECKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHTGEKP--- 475

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   + H R H G
Sbjct: 476 -YECKQCGKAFSFSSSFRMHERTHTG 500



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 32/86 (37%), Positives = 50/86 (58%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S+ +MH RTHTGE+P++CK CG+AF+   +++ H   H  + P   
Sbjct: 503 PYECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKP--- 559

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +  ++ H R H G
Sbjct: 560 -YECKQCGKAFSCSSSVRMHERTHTG 584



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S+ +MH RTHTGE+P +CK CG+AF+   +++ H   H  + P   
Sbjct: 391 PYECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRIHERTHTGEKP--- 447

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   + H R+H G
Sbjct: 448 -YECKQCGKAFSCSSSFRMHERIHTG 472



 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P QC  C + LSC ++ + H R HTGE+P+KCK CG+AF+   + + H  +H  + P   
Sbjct: 279 PYQCKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGEKP--- 335

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F +    ++H+ MH G
Sbjct: 336 -YDCKECGKAFISLPSYRRHMIMHTG 360



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 55/191 (28%), Positives = 78/191 (40%), Gaps = 36/191 (18%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+ +S+  IH R+HT E+P+ C  C +  S   + + H  TH   E P +  +
Sbjct: 142  CKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTH-TGEKPYECKE 200

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
               A                 +      GH + M  GE P      +     +T   P  
Sbjct: 201  CGKAF----------------IYHTTFRGHMR-MHTGEKP-----YKCKECGKTFSHPSS 238

Query: 1099 APMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTT 1152
                    R   + H+      C+ CGK F      QIHERTHTGEKP+ C  CG+A + 
Sbjct: 239  F-------RNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSC 291

Query: 1153 KGNLKVHMGTH 1163
              + + H   H
Sbjct: 292  PTSFRSHERIH 302



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 55/201 (27%), Positives = 76/201 (37%), Gaps = 46/201 (22%)

Query: 979  CGVCGKPFACKSALEIHYRSHTK----------ERPFVCALCRRGCSTMGNLKQHLLTHR 1028
            C VCGK + C S+L  H RSHT+          E+ + C  C +  S   + + H  TH 
Sbjct: 104  CSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHERTH- 162

Query: 1029 LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPA 1088
                                     +   P   K      GKA +      +        
Sbjct: 163  -------------------------TGEKPYKCKQ----CGKAFSWPSSFQIHERTHTGE 193

Query: 1089 GPQTVMGPGLAPMLAPPPRRTPKQH------NCQSCGKTFSSASALQIHERTHTGEKPFG 1142
             P      G A +     R   + H       C+ CGKTFS  S+ + HERTH+GEKP+ 
Sbjct: 194  KPYECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHPSSFRNHERTHSGEKPYE 253

Query: 1143 CTICGRAFTTKGNLKVHMGTH 1163
            C  CG+AF      ++H  TH
Sbjct: 254  CKQCGKAFRYYQTFQIHERTH 274



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S++++H RTHTGE+P++CK CG+AF+   +++ H   H    P   
Sbjct: 531 PYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKP--- 587

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   + H R H G
Sbjct: 588 -YECKQCDKAFSCSRSFRIHERTHTG 612



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +   C S+ ++H RTHTGE+P++CK CG+AF+   + + H   H  + P   
Sbjct: 363 PYKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKP--- 419

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            H C  C K F+ +  ++ H R H G
Sbjct: 420 -HECKQCGKAFSCSSSVRIHERTHTG 444



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S+ +MH R HTGE+P++CK CG+AF+   + + H   H  + P   
Sbjct: 447 PYECKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHTGEKP--- 503

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   + H R H G
Sbjct: 504 -YECKQCGKAFSCSSSFRMHERTHTG 528



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S  S+ +MH RTHTGE+P++CK CG+AF+   + + H   H  + P   
Sbjct: 475 PYECKQCGKAFSFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKP--- 531

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +  ++ H R H G
Sbjct: 532 -YECKQCGKAFSCSSSIRIHERTHTG 556



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 4/84 (4%)

Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           +C  C +  S +S+ ++H RTHTGE+P+KCK CG+AF+   + + H   H  + P    +
Sbjct: 141 ECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTHTGEKP----Y 196

Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763
            C  C K F      + H+RMH G
Sbjct: 197 ECKECGKAFIYHTTFRGHMRMHTG 220



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S+++MH RTHTG +P++CK C +AF+   + + H   H  + P   
Sbjct: 559 PYECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRSFRIHERTHTGEKP--- 615

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            ++C  C K F  +   + H R+H G
Sbjct: 616 -YACQQCGKAFKCSRSFRIHERVHSG 640



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S  S+ ++H RTHTGE+P++CK CG+AF      + H  +H  + P   
Sbjct: 167 PYKCKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRGHMRMHTGEKP--- 223

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F++    + H R H G
Sbjct: 224 -YKCKECGKTFSHPSSFRNHERTHSG 248



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +        ++H RTHTGE+P++CK CG+A +   + ++H  +H  + P   
Sbjct: 251 PYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSCPTSFRSHERIHTGEKP--- 307

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+     ++H R+H G
Sbjct: 308 -YKCKKCGKAFSFPSSFRKHERIHTG 332



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 24/57 (42%), Positives = 36/57 (63%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   S+ QIH R+HTGE+P++C  CG  FS   + ++H + H  + PH
Sbjct: 364 YKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPH 420



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S  S+ + H R HTGE+P+ CK CG+AF +  + + H  +H    P   
Sbjct: 307 PYKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGKAFISLPSYRRHMIMHTGNGP--- 363

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F      Q H R H G
Sbjct: 364 -YKCKECGKAFDCPSSFQIHERTHTG 388



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +     +  + H R HTGE+P+KCK CG+ F+   + + H   H  + P   
Sbjct: 195 PYECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHPSSFRNHERTHSGEKP--- 251

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F      Q H R H G
Sbjct: 252 -YECKQCGKAFRYYQTFQIHERTHTG 276



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S  S+ + H RTH+GE+P++CK CG+AF      + H   H  + P   
Sbjct: 223 PYKCKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKP--- 279

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K  +     + H R+H G
Sbjct: 280 -YQCKQCGKALSCPTSFRSHERIHTG 304



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 22/57 (38%), Positives = 37/57 (64%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           H+C+ C K F   S+++IH R+HTGE+P++C  CG  FS   + ++H + H  + P+
Sbjct: 420 HECKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHTGEKPY 476



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P +  + E   + E P+   +C+ C K F   S+ ++H R+HTGE+P +C  CG  FS  
Sbjct: 376 PSSFQIHERTHTGEKPY---ECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCS 432

Query: 461 GNLKVHFQRHKEKYPH 476
            ++++H + H  + P+
Sbjct: 433 SSVRIHERTHTGEKPY 448



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 50/181 (27%), Positives = 71/181 (39%), Gaps = 30/181 (16%)

Query: 962  FSLLFLSRER---GKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMG 1018
            FS  F   ER   G+ P   C  CGK F+C S+  +H R+HT E+P+ C  C +  S   
Sbjct: 487  FSSSFRMHERTHTGEKPYE-CKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSS 545

Query: 1019 NLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEG 1077
            +++ H  TH   E P +      A   S S    +     T +K  E     KA +    
Sbjct: 546  SIRIHERTHT-GEKPYECKQCGKAFSCSSSVR--MHERTHTGVKPYECKQCDKAFSCSRS 602

Query: 1078 PPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTG 1137
              +         P                      + CQ CGK F  + + +IHER H+G
Sbjct: 603  FRIHERTHTGEKP----------------------YACQQCGKAFKCSRSFRIHERVHSG 640

Query: 1138 E 1138
            E
Sbjct: 641  E 641



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 20/57 (35%), Positives = 37/57 (64%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F   S+ ++H R+HTGE+P++C  CG  FS   ++++H + H  + P+
Sbjct: 504 YECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPY 560



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 21/57 (36%), Positives = 37/57 (64%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F   S+++IH R+HTGE+P++C  CG  FS   ++++H + H    P+
Sbjct: 532 YECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKPY 588



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 14/96 (14%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHT----------GERPFKCKICGRAFTTKGNLKTHFG 727
           P +C +C +   C S+L  H R+HT          GE+ ++CK CG+ F+ + + + H  
Sbjct: 101 PYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHER 160

Query: 728 VHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
            H  + P    + C  C K F+     Q H R H G
Sbjct: 161 THTGEKP----YKCKQCGKAFSWPSSFQIHERTHTG 192



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 3/74 (4%)

Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462
           +V + E   + E P+   +C+ C K F   S+ ++H R HTGE+P++C  CG  FS   +
Sbjct: 434 SVRIHERTHTGEKPY---ECKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSS 490

Query: 463 LKVHFQRHKEKYPH 476
            ++H + H  + P+
Sbjct: 491 FRMHERTHTGEKPY 504



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 22/57 (38%), Positives = 36/57 (63%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F   S+ +IH R+HTGE+P+KC  CG  FS   + ++H + H  + P+
Sbjct: 140 YECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTHTGEKPY 196



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 20/57 (35%), Positives = 36/57 (63%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F   S+ ++H R+HTGE+P++C  CG  FS   + ++H + H  + P+
Sbjct: 476 YECKQCGKAFSFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPY 532



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 3/71 (4%)

Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465
           + E   + E P+   KC+ C K F   S+ QIH R+HTGE+P++C  CG  F      + 
Sbjct: 157 IHERTHTGEKPY---KCKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRG 213

Query: 466 HFQRHKEKYPH 476
           H + H  + P+
Sbjct: 214 HMRMHTGEKPY 224



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P +  + E   + E P+   +C+ C K F   +  + H+R HTGE+P+KC  CG  FS  
Sbjct: 180 PSSFQIHERTHTGEKPY---ECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHP 236

Query: 461 GNLKVHFQRHKEKYPH 476
            + + H + H  + P+
Sbjct: 237 SSFRNHERTHSGEKPY 252



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +      + + H   HTG  P+KCK CG+AF    + + H   H  + P   
Sbjct: 335 PYDCKECGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKP--- 391

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   + H R H G
Sbjct: 392 -YECKQCGKAFSCSSSFRMHERTHTG 416



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 3/74 (4%)

Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462
           ++ + E   + E P+   +C+ C K F   S++++H R+HTG +P++C  C   FS   +
Sbjct: 546 SIRIHERTHTGEKPY---ECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRS 602

Query: 463 LKVHFQRHKEKYPH 476
            ++H + H  + P+
Sbjct: 603 FRIHERTHTGEKPY 616



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 19/57 (33%), Positives = 33/57 (57%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   S+ + H R+H+GE+P++C  CG  F      ++H + H  + P+
Sbjct: 224 YKCKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPY 280



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P +    E   S E P+   +C+ C K F      QIH R+HTGE+P++C  CG   S  
Sbjct: 236 PSSFRNHERTHSGEKPY---ECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSCP 292

Query: 461 GNLKVHFQRHKEKYPH 476
            + + H + H  + P+
Sbjct: 293 TSFRSHERIHTGEKPY 308



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 18/51 (35%), Positives = 30/51 (58%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
           ++C+ C K F    + +IH R+HTGE+P+ C  CG  F    + ++H + H
Sbjct: 588 YECKQCDKAFSCSRSFRIHERTHTGEKPYACQQCGKAFKCSRSFRIHERVH 638



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 3/71 (4%)

Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465
           + E   + E P+   +C+ C K     ++ + H R HTGE+P+KC  CG  FS   + + 
Sbjct: 269 IHERTHTGEKPY---QCKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRK 325

Query: 466 HFQRHKEKYPH 476
           H + H  + P+
Sbjct: 326 HERIHTGEKPY 336



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 20/57 (35%), Positives = 30/57 (52%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   S+ + H R HTGE+P+ C  CG  F +  + + H   H    P+
Sbjct: 308 YKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGKAFISLPSYRRHMIMHTGNGPY 364



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 10/67 (14%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHT----------GERPFKCNICGNRFSTKGNLKVHFQR 469
           ++C  C K +   S+L  H+RSHT          GE+ ++C  CG RFS + + ++H + 
Sbjct: 102 YECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHERT 161

Query: 470 HKEKYPH 476
           H  + P+
Sbjct: 162 HTGEKPY 168



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 10/63 (15%)

Query: 1111 KQHNCQSCGKTFSSASALQIHERTHT----------GEKPFGCTICGRAFTTKGNLKVHM 1160
            K + C  CGK +   S+L  H R+HT          GEK + C  CG+ F+ + + ++H 
Sbjct: 100  KPYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHE 159

Query: 1161 GTH 1163
             TH
Sbjct: 160  RTH 162



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 18/57 (31%), Positives = 30/57 (52%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           + C+ C K F S  + + H+  HTG  P+KC  CG  F    + ++H + H  + P+
Sbjct: 336 YDCKECGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKPY 392



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 14/45 (31%), Positives = 26/45 (57%)

Query: 1119 GKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            G+T S     + +++T T  KP+ C++CG+ +    +L  HM +H
Sbjct: 80   GETISQTPNPKPNKKTFTRVKPYECSVCGKDYMCHSSLNRHMRSH 124



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 6/75 (8%)

Query: 695 KMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV------QHSCPICQKKF 748
           K + +T T  +P++C +CG+ +    +L  H   H               + C  C K+F
Sbjct: 90  KPNKKTFTRVKPYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRF 149

Query: 749 TNAVVLQQHIRMHMG 763
           +     + H R H G
Sbjct: 150 SFRSSFRIHERTHTG 164


>gi|40807465 zinc finger protein 341 [Homo sapiens]
          Length = 847

 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 98/338 (28%), Positives = 126/338 (37%), Gaps = 69/338 (20%)

Query: 142 TRAPRPPPAAPAP----PTPAYGAPSTNVTL--EALLSTKVAVAQFSQGARAAGGSGAGG 195
           T +  PP AAP      PTPA    ST +T+    L+ T V            G      
Sbjct: 90  TNSIYPPSAAPTAVQQAPTPANRQISTYITVPPSPLIQTLVQ-----------GNILVSD 138

Query: 196 GVAAAAVPLI--LEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGP 253
            V  +A+     L+Q M      +     +  + S +     PPP P   P   P  P P
Sbjct: 139 DVLMSAMSAFTSLDQPMPQGPPPVQSSLNMHSVPSYLTQPPPPPPPPPPLPPPPPPQPPP 198

Query: 254 APSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAA 313
            P         P S G P     G G      +  A PL+    G+ T    A    P  
Sbjct: 199 PP---------PQSLGPPGRPNPG-GNGVVEVYSAAAPLA----GSGTVEIQALGMQPYP 244

Query: 314 PSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIF 373
           P   P                 +P    TP   +PG   G  P  P+P  P TSA+G   
Sbjct: 245 PLEVPNQCV-------------EPPVYPTPTVYSPGKQ-GFKPKGPNPAAPMTSATG--- 287

Query: 374 PNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDS 433
                    T    D   A +K R+ K       +PKA       K KC +C K F  + 
Sbjct: 288 --------GTVATFDS-PATLKTRRAKAAG----KPKAQ------KLKCSYCDKSFTKNF 328

Query: 434 ALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
            LQ H+RSHTGE+PF+C  CG  F+ K N+K H Q HK
Sbjct: 329 DLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHK 366



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 63/267 (23%), Positives = 98/267 (36%), Gaps = 46/267 (17%)

Query: 925  PEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERG------------ 972
            P  P E+P +   P  P     +  +PG+ G K + P     ++   G            
Sbjct: 242  PYPPLEVPNQCVEP--PVYPTPTVYSPGKQGFKPKGPNPAAPMTSATGGTVATFDSPATL 299

Query: 973  -----------KCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLK 1021
                       K     C  C K F     L+ H RSHT E+PF C  C R  +   N+K
Sbjct: 300  KTRRAKAAGKPKAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVK 359

Query: 1022 QHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLP 1081
            +H+ TH++           +  G S  T S  +S    ++ +  +      + G G PLP
Sbjct: 360  KHMQTHKV-----------WPPGHSGGTVSR-NSVTVQVMALNPSRQEDEESTGLGQPLP 407

Query: 1082 AGVQVPAGPQTVMGPGLAPMLAPPPRRT---PKQHNCQSCGKTFSSASALQIHERTHTGE 1138
               Q    PQ +   G      P  ++       + CQ C   FS+   L+ H   H  E
Sbjct: 408  GAPQ----PQALSTAGEEEGDKPESKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKNE 463

Query: 1139 KPFGCTI--CGRAFTTKGNLKVHMGTH 1163
            + + C +  C + F        H+ +H
Sbjct: 464  QVYKCVVKSCAQTFPKLDTFLEHIKSH 490



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 73/308 (23%), Positives = 109/308 (35%), Gaps = 55/308 (17%)

Query: 479 MNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAH 538
           +N + VP YL   P           PP  P        P LP  P     Q PP  P + 
Sbjct: 166 LNMHSVPSYLTQPPP----------PPPPP--------PPLPPPPPP---QPPPPPPQSL 204

Query: 539 GYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEP 598
           G             P RP+P  +       G+  V S  +  A S    +    +    P
Sbjct: 205 G------------PPGRPNPGGN-------GVVEVYSAAAPLAGSGTVEIQALGMQPYPP 245

Query: 599 VSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQT 658
           + +P    +  + PV    +       G      +P  P  S         GG + +  +
Sbjct: 246 LEVP---NQCVEPPVYPTPTVYSPGKQGFKPKGPNPAAPMTSAT-------GGTVATFDS 295

Query: 659 SETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTT 718
             T K ++  +   K      +C  C +  +    L+ H R+HTGE+PF+C  CGRAF  
Sbjct: 296 PATLKTRR-AKAAGKPKAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQ 354

Query: 719 KGNLKTHFGVHRAKPPLR----VQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEG 774
           K N+K H   H+  PP      V  +    Q    N    +      +G  +P  P P+ 
Sbjct: 355 KSNVKKHMQTHKVWPPGHSGGTVSRNSVTVQVMALNPSRQEDEESTGLGQPLPGAPQPQA 414

Query: 775 FQDAMDSE 782
              A + E
Sbjct: 415 LSTAGEEE 422



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 9/89 (10%)

Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           +C +C +    +  LK+H   H+GE+P+KC +C  AF  K  LK H  +H    P + ++
Sbjct: 588 KCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHE---PFK-KY 643

Query: 740 SCPI-----CQKKFTNAVVLQQHIRMHMG 763
            CP      C K+F     L+ HI  H G
Sbjct: 644 KCPFSTHTGCSKEFNRPDKLKAHILSHSG 672



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 69/290 (23%), Positives = 105/290 (36%), Gaps = 42/290 (14%)

Query: 891  AGSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGA 950
            +G      S + Q ++  PS  E   S   G   P  PQ   L T              A
Sbjct: 373  SGGTVSRNSVTVQVMALNPSRQEDEESTGLGQPLPGAPQPQALST--------------A 418

Query: 951  PGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCAL- 1009
                G K E+   +L  S       S +C  C   F+    L+ H   H  E+ + C + 
Sbjct: 419  GEEEGDKPESKQVVLIDS-------SYLCQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVK 471

Query: 1010 -CRRGCSTMGNLKQHLLTHRLK-----ELPSQLFDPNFALGPSQSTPSLISSAAPTMIKM 1063
             C +    +    +H+ +H+ +      L  + F   + LG  Q + SL+   +P     
Sbjct: 472  SCAQTFPKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHSLLPQHSPK---- 527

Query: 1064 EVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQH---------- 1113
            + N   K +        P  ++      T   P        P  R  ++H          
Sbjct: 528  KDNAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHCQKVFPCERYLRRHLPTHGSGGRF 587

Query: 1114 NCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
             CQ C K F     L++H   H+GEKP+ C++C  AF  K  LK HM  H
Sbjct: 588  KCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIH 637



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 44/181 (24%), Positives = 64/181 (35%), Gaps = 47/181 (25%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C VC K F  +  L++H   H+ E+P+ C++C    +    LK+H+L H     P + + 
Sbjct: 589  CQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHE----PFKKYK 644

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
              F    S  T        P  +K  +  H                              
Sbjct: 645  CPF----STHTGCSKEFNRPDKLKAHILSHSGM--------------------------- 673

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                        K H C  C K+FS  + L  H+R HTG   F C  C + F+    LK 
Sbjct: 674  ------------KLHKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKD 721

Query: 1159 H 1159
            H
Sbjct: 722  H 722



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 4/81 (4%)

Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740
           C  C +V  C+  L+ H  TH     FKC++C + F  +  LK H  +H  + P    + 
Sbjct: 561 CPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIHSGEKP----YK 616

Query: 741 CPICQKKFTNAVVLQQHIRMH 761
           C +C+  F     L++H+ +H
Sbjct: 617 CSVCESAFNRKDKLKRHMLIH 637



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 20/53 (37%), Positives = 33/53 (62%)

Query: 419 KHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           + KC+ C K F  +  L++H   H+GE+P+KC++C + F+ K  LK H   H+
Sbjct: 586 RFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHE 638



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 15/94 (15%)

Query: 396 HRKGKPPNVSVFEPKASAED----------PFFKHKCRF-----CAKVFGSDSALQIHLR 440
           H   KP   SV E   + +D          PF K+KC F     C+K F     L+ H+ 
Sbjct: 609 HSGEKPYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSTHTGCSKEFNRPDKLKAHIL 668

Query: 441 SHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKY 474
           SH+G +  KC +C   FS + +L  H + H   Y
Sbjct: 669 SHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNY 702



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 25/91 (27%), Positives = 35/91 (38%), Gaps = 9/91 (9%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKI-----CGRAFTTKGNLKTHFGVHRAK 732
           P +C +C    + +  LK H   H   + +KC       C + F     LK H   H   
Sbjct: 614 PYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSTHTGCSKEFNRPDKLKAHILSHSGM 673

Query: 733 PPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
                 H C +C K F+    L +H R H G
Sbjct: 674 K----LHKCALCSKSFSRRAHLAEHQRAHTG 700



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 112/553 (20%), Positives = 168/553 (30%), Gaps = 128/553 (23%)

Query: 240 PSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAA---IAGSGPAAPAAFEGAQPLSRPE 296
           PS +P A   AP PA  Q+     +P S          I  S     +A      L +P 
Sbjct: 96  PSAAPTAVQQAPTPANRQISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQP- 154

Query: 297 SGASTPGGP----------AEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPAL 346
                P GP          + PS    P   P P  P P P P       PQS   P   
Sbjct: 155 ----MPQGPPPVQSSLNMHSVPSYLTQPPPPPPPPPPLPPPPPPQPPPPPPQSLGPPGRP 210

Query: 347 APGS-----LLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKP 401
            PG      +  AA  L      +  A G+    P   +      ++P   +        
Sbjct: 211 NPGGNGVVEVYSAAAPLAGSGTVEIQALGM---QPYPPLEVPNQCVEP--PVYPTPTVYS 265

Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGE---RPFKCNICGNRFS 458
           P    F+PK                  F S + L+       G+   +  KC+ C   F+
Sbjct: 266 PGKQGFKPKGPNPAAPMTSATGGTVATFDSPATLKTRRAKAAGKPKAQKLKCSYCDKSFT 325

Query: 459 TKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPV 518
              +L+ H +       H    P+              I  G +   +  V   + +  V
Sbjct: 326 KNFDLQQHIRS------HTGEKPFQC------------IACGRAFAQKSNVKKHMQTHKV 367

Query: 519 LPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVS 578
            P              PG  G   S ++         PS    E    S GL        
Sbjct: 368 WP--------------PGHSGGTVSRNSVTVQVMALNPSRQEDE---ESTGLG------- 403

Query: 579 ATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPA 638
                 Q L G P     +P +L       GD P   Q                   +  
Sbjct: 404 ------QPLPGAP-----QPQALSTAGEEEGDKPESKQ-------------------VVL 433

Query: 639 VSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDK-KMTDPNQCVI--CHRVLSCQSALK 695
           +   +  QF           S+ S   QL  ++ + K     +CV+  C +         
Sbjct: 434 IDSSYLCQFC---------PSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFL 484

Query: 696 MHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS---------CPICQK 746
            H ++H  E  ++C +CG+ F +  +L    GVH+    L  QHS         C  C  
Sbjct: 485 EHIKSHQEELSYRCHLCGKDFPSLYDL----GVHQYSHSLLPQHSPKKDNAVYKCVKCVN 540

Query: 747 KFTNAVVLQQHIR 759
           K++    L+ H++
Sbjct: 541 KYSTPEALEHHLQ 553



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 20/47 (42%), Positives = 24/47 (51%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVH 466
           HKC  C+K F   + L  H R+HTG   F+C  C   FS    LK H
Sbjct: 676 HKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKDH 722



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 5/82 (6%)

Query: 684 CHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPI 743
           C +  +    LK H  +H+G +  KC +C ++F+ + +L  H   H      R    C  
Sbjct: 653 CSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNYKFR----CAG 708

Query: 744 CQKKFTNAVVLQQHIRMHMGGQ 765
           C K F+    L+ H R  +G Q
Sbjct: 709 CAKGFSRHKYLKDH-RCRLGPQ 729



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 19/55 (34%), Positives = 27/55 (49%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           C  C KVF  +  L+ HL +H     FKC +C   F  +  LK+H   H  + P+
Sbjct: 561 CPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIHSGEKPY 615



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 16/47 (34%), Positives = 25/47 (53%)

Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTH 725
           ++C +C +  S ++ L  H R HTG   F+C  C + F+    LK H
Sbjct: 676 HKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKDH 722



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 15/49 (30%), Positives = 25/49 (51%)

Query: 1118 CGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWN 1166
            C K F+    L+ H  +H+G K   C +C ++F+ + +L  H   H  N
Sbjct: 653  CSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGN 701



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 12/98 (12%)

Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHT---------GERPFKCNI 452
           P +  F     +      ++C  C K F S   L +H  SH+             +KC  
Sbjct: 478 PKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHSLLPQHSPKKDNAVYKCVK 537

Query: 453 CGNRFSTKGNLKVHFQ--RHKEKYPHIQMNPYPVPEYL 488
           C N++ST   L+ H Q   H    PH Q   +P   YL
Sbjct: 538 CVNKYSTPEALEHHLQTATHNFPCPHCQ-KVFPCERYL 574



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 18/55 (32%), Positives = 25/55 (45%)

Query: 973  KCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
            KCP +    C K F     L+ H  SH+  +   CALC +  S   +L +H   H
Sbjct: 644  KCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAH 698



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 22/83 (26%), Positives = 31/83 (37%), Gaps = 6/83 (7%)

Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKC--KICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738
           C  C    S    LK H   H  E+ +KC  K C + F        H   H+ +    + 
Sbjct: 440 CQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEE----LS 495

Query: 739 HSCPICQKKFTNAVVLQQHIRMH 761
           + C +C K F +   L  H   H
Sbjct: 496 YRCHLCGKDFPSLYDLGVHQYSH 518


>gi|33438586 zinc finger protein 77 [Homo sapiens]
          Length = 545

 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 64/196 (32%), Positives = 91/196 (46%), Gaps = 18/196 (9%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F+C S    H R+HT E+P+ C  C +  S   + + H+ TH   E P Q   
Sbjct: 270  CKECGKAFSCPSYFREHVRTHTGEKPYECKHCGKSFSCYSSFRDHVRTHT-GEKPCQCKH 328

Query: 1039 PNFALGPSQSTPSLISSAAPTMI---KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095
                 G + +  S +     T       E    GKA        L A +++  G +  + 
Sbjct: 329  ----CGKAFTCYSSLREHGRTHSGEKPYECKECGKAFRYPSS--LRAHMRMHTGEKPYVC 382

Query: 1096 PGLAPMLAPPP--RRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICG 1147
                     P   RR  K H+      C+ CGK +S +S+L+IH RTHTGEKPF C  CG
Sbjct: 383  KQCGKAFGCPTYFRRHVKTHSGVKPYQCKECGKAYSFSSSLRIHVRTHTGEKPFECKHCG 442

Query: 1148 RAFTTKGNLKVHMGTH 1163
            +AF+   +L+ H+ TH
Sbjct: 443  KAFSCHSSLREHVRTH 458



 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 62/195 (31%), Positives = 91/195 (46%), Gaps = 16/195 (8%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRR--GCSTMGNLKQHLLTHRLKELPSQL 1036
            C  CGK F   S+L  H R HT E+P+VC  C +  GC T    ++H+ TH   + P Q 
Sbjct: 354  CKECGKAFRYPSSLRAHMRMHTGEKPYVCKQCGKAFGCPTY--FRRHVKTHSGVK-PYQC 410

Query: 1037 FDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAG--PQTVM 1094
             +   A   S S    + +        E    GKA +      L   V+  +G  P    
Sbjct: 411  KECGKAYSFSSSLRIHVRTHTGEK-PFECKHCGKAFSCHSS--LREHVRTHSGEKPYECN 467

Query: 1095 GPGLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGR 1148
              G A   A   ++  + H+      C  CGK +S +S+L++H RTHTGE+P+ C  CG+
Sbjct: 468  QCGKAFSHAQYFQKHVRSHSGVKPYECTECGKAYSCSSSLRVHVRTHTGERPYECKQCGK 527

Query: 1149 AFTTKGNLKVHMGTH 1163
             F    +L+ H+ TH
Sbjct: 528  TFRYLASLQAHVRTH 542



 Score = 81.6 bits (200), Expect = 4e-15
 Identities = 36/86 (41%), Positives = 52/86 (60%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P QC  C +  S  S+L++H RTHTGE+PF+CK CG+AF+   +L+ H   H  + P   
Sbjct: 407 PYQCKECGKAYSFSSSLRIHVRTHTGEKPFECKHCGKAFSCHSSLREHVRTHSGEKP--- 463

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F++A   Q+H+R H G
Sbjct: 464 -YECNQCGKAFSHAQYFQKHVRSHSG 488



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 35/86 (40%), Positives = 48/86 (55%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S+ + H RTHTGE+P +CK CG+AFT   +L+ H   H  + P   
Sbjct: 295 PYECKHCGKSFSCYSSFRDHVRTHTGEKPCQCKHCGKAFTCYSSLREHGRTHSGEKP--- 351

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F     L+ H+RMH G
Sbjct: 352 -YECKECGKAFRYPSSLRAHMRMHTG 376



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P QC  C +  +C S+L+ H RTH+GE+P++CK CG+AF    +L+ H  +H  + P   
Sbjct: 323 PCQCKHCGKAFTCYSSLREHGRTHSGEKPYECKECGKAFRYPSSLRAHMRMHTGEKP--- 379

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F      ++H++ H G
Sbjct: 380 -YVCKQCGKAFGCPTYFRRHVKTHSG 404



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S  + H RTHTGE+P++CK CG++F+   + + H   H  + P + 
Sbjct: 267 PYECKECGKAFSCPSYFREHVRTHTGEKPYECKHCGKSFSCYSSFRDHVRTHTGEKPCQC 326

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
           +H    C K FT    L++H R H G
Sbjct: 327 KH----CGKAFTCYSSLREHGRTHSG 348



 Score = 71.2 bits (173), Expect = 6e-12
 Identities = 59/235 (25%), Positives = 87/235 (37%), Gaps = 65/235 (27%)

Query: 929  QEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFAC 988
            Q  P+KT+  + P     S  A            S+ ++     K  S  C  CGK F C
Sbjct: 177  QSPPMKTQTVEKPCNCQDSRTA------------SVTYVKSLSSK-KSYECQKCGKAFIC 223

Query: 989  KSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQS 1048
             S+   H  SH  ++   C +C +       L +H+ TH  ++             P + 
Sbjct: 224  PSSFRGHVNSHHGQKTHACKVCGKTFMYYSYLTRHVRTHTGEK-------------PYEC 270

Query: 1049 TPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRR 1108
                 + + P+  +  V  H      GE P                              
Sbjct: 271  KECGKAFSCPSYFREHVRTH-----TGEKP------------------------------ 295

Query: 1109 TPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
                + C+ CGK+FS  S+ + H RTHTGEKP  C  CG+AFT   +L+ H  TH
Sbjct: 296  ----YECKHCGKSFSCYSSFRDHVRTHTGEKPCQCKHCGKAFTCYSSLREHGRTH 346



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  SC S+L+ H RTH+GE+P++C  CG+AF+     + H   H    P   
Sbjct: 435 PFECKHCGKAFSCHSSLREHVRTHSGEKPYECNQCGKAFSHAQYFQKHVRSHSGVKP--- 491

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K ++ +  L+ H+R H G
Sbjct: 492 -YECTECGKAYSCSSSLRVHVRTHTG 516



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +   C +  + H +TH+G +P++CK CG+A++   +L+ H   H  + P   
Sbjct: 379 PYVCKQCGKAFGCPTYFRRHVKTHSGVKPYQCKECGKAYSFSSSLRIHVRTHTGEKPFEC 438

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
           +H    C K F+    L++H+R H G
Sbjct: 439 KH----CGKAFSCHSSLREHVRTHSG 460



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 4/83 (4%)

Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740
           C +C +     S L  H RTHTGE+P++CK CG+AF+     + H   H  + P    + 
Sbjct: 242 CKVCGKTFMYYSYLTRHVRTHTGEKPYECKECGKAFSCPSYFREHVRTHTGEKP----YE 297

Query: 741 CPICQKKFTNAVVLQQHIRMHMG 763
           C  C K F+     + H+R H G
Sbjct: 298 CKHCGKSFSCYSSFRDHVRTHTG 320



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 46/159 (28%), Positives = 67/159 (42%), Gaps = 24/159 (15%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK ++  S+L IH R+HT E+PF C  C +  S   +L++H+ TH   E P +   
Sbjct: 410  CKECGKAYSFSSSLRIHVRTHTGEKPFECKHCGKAFSCHSSLREHVRTHS-GEKPYECNQ 468

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
               A   +Q     + S +      E    GKA +      L   V+   G         
Sbjct: 469  CGKAFSHAQYFQKHVRSHSGVK-PYECTECGKAYSCSSS--LRVHVRTHTGE-------- 517

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTG 1137
                        + + C+ CGKTF   ++LQ H RTH G
Sbjct: 518  ------------RPYECKQCGKTFRYLASLQAHVRTHAG 544



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 57/185 (30%), Positives = 72/185 (38%), Gaps = 38/185 (20%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F      E   RSHT +RP  C  C + CS +      + T  + E P    D
Sbjct: 144  CTKCGKAF------ENRQRSHTGQRP--CKECGQACSCLSCQSPPMKTQTV-EKPCNCQD 194

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
               A   S +    +SS        E    GKA                  P +  G   
Sbjct: 195  SRTA---SVTYVKSLSSKK----SYECQKCGKAFIC---------------PSSFRGHVN 232

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
            +           K H C+ CGKTF   S L  H RTHTGEKP+ C  CG+AF+     + 
Sbjct: 233  S-------HHGQKTHACKVCGKTFMYYSYLTRHVRTHTGEKPYECKECGKAFSCPSYFRE 285

Query: 1159 HMGTH 1163
            H+ TH
Sbjct: 286  HVRTH 290



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 24/52 (46%), Positives = 34/52 (65%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729
           P +C  C +  SC S+L++H RTHTGERP++CK CG+ F    +L+ H   H
Sbjct: 491 PYECTECGKAYSCSSSLRVHVRTHTGERPYECKQCGKTFRYLASLQAHVRTH 542



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 11/98 (11%)

Query: 390 LSALMKHRKGKPPNVSVFEPKASAEDPFFK-----------HKCRFCAKVFGSDSALQIH 438
           L A M+   G+ P V     KA     +F+           ++C+ C K +   S+L+IH
Sbjct: 367 LRAHMRMHTGEKPYVCKQCGKAFGCPTYFRRHVKTHSGVKPYQCKECGKAYSFSSSLRIH 426

Query: 439 LRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +R+HTGE+PF+C  CG  FS   +L+ H + H  + P+
Sbjct: 427 VRTHTGEKPFECKHCGKAFSCHSSLREHVRTHSGEKPY 464



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +     S+L+ H R HTGE+P+ CK CG+AF      + H   H    P   
Sbjct: 351 PYECKECGKAFRYPSSLRAHMRMHTGEKPYVCKQCGKAFGCPTYFRRHVKTHSGVKP--- 407

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K ++ +  L+ H+R H G
Sbjct: 408 -YQCKECGKAYSFSSSLRIHVRTHTG 432



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S     + H R+H+G +P++C  CG+A++   +L+ H   H  + P   
Sbjct: 463 PYECNQCGKAFSHAQYFQKHVRSHSGVKPYECTECGKAYSCSSSLRVHVRTHTGERP--- 519

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F     LQ H+R H G
Sbjct: 520 -YECKQCGKTFRYLASLQAHVRTHAG 544



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           +C  C +   C S+ + H  +H G++   CK+CG+ F     L  H   H  + P    +
Sbjct: 213 ECQKCGKAFICPSSFRGHVNSHHGQKTHACKVCGKTFMYYSYLTRHVRTHTGEKP----Y 268

Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763
            C  C K F+     ++H+R H G
Sbjct: 269 ECKECGKAFSCPSYFREHVRTHTG 292



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 3/65 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           + E PF   +C+ C K F   S+L+ H+R+H+GE+P++CN CG  FS     + H + H 
Sbjct: 431 TGEKPF---ECKHCGKAFSCHSSLREHVRTHSGEKPYECNQCGKAFSHAQYFQKHVRSHS 487

Query: 472 EKYPH 476
              P+
Sbjct: 488 GVKPY 492



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 20/51 (39%), Positives = 33/51 (64%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470
           ++C  C K +   S+L++H+R+HTGERP++C  CG  F    +L+ H + H
Sbjct: 492 YECTECGKAYSCSSSLRVHVRTHTGERPYECKQCGKTFRYLASLQAHVRTH 542



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 22/57 (38%), Positives = 32/57 (56%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           H C+ C K F   S L  H+R+HTGE+P++C  CG  FS     + H + H  + P+
Sbjct: 240 HACKVCGKTFMYYSYLTRHVRTHTGEKPYECKECGKAFSCPSYFREHVRTHTGEKPY 296



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 5/84 (5%)

Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQM- 479
           +C+ C K F   S+L+ H R+H+GE+P++C  CG  F    +L+ H + H  + P++   
Sbjct: 325 QCKHCGKAFTCYSSLREHGRTHSGEKPYECKECGKAFRYPSSLRAHMRMHTGEKPYVCKQ 384

Query: 480 --NPYPVPEYL-DNVPTCSGI-PY 499
               +  P Y   +V T SG+ PY
Sbjct: 385 CGKAFGCPTYFRRHVKTHSGVKPY 408



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 3/65 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           S E P+   +C  C K F      Q H+RSH+G +P++C  CG  +S   +L+VH + H 
Sbjct: 459 SGEKPY---ECNQCGKAFSHAQYFQKHVRSHSGVKPYECTECGKAYSCSSSLRVHVRTHT 515

Query: 472 EKYPH 476
            + P+
Sbjct: 516 GERPY 520



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 20/56 (35%), Positives = 33/56 (58%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475
           ++C+ C K F   S  + H+R+HTGE+P++C  CG  FS   + + H + H  + P
Sbjct: 268 YECKECGKAFSCPSYFREHVRTHTGEKPYECKHCGKSFSCYSSFRDHVRTHTGEKP 323



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 20/57 (35%), Positives = 35/57 (61%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F   S+ + H+R+HTGE+P +C  CG  F+   +L+ H + H  + P+
Sbjct: 296 YECKHCGKSFSCYSSFRDHVRTHTGEKPCQCKHCGKAFTCYSSLREHGRTHSGEKPY 352



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 32/127 (25%), Positives = 49/127 (38%), Gaps = 26/127 (20%)

Query: 659 SETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERP------------ 706
           SE +K  +  EN  +  T    C  C +  SC S      +T T E+P            
Sbjct: 142 SECTKCGKAFENRQRSHTGQRPCKECGQACSCLSCQSPPMKTQTVEKPCNCQDSRTASVT 201

Query: 707 ----------FKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQ 756
                     ++C+ CG+AF    + + H   H  +      H+C +C K F     L +
Sbjct: 202 YVKSLSSKKSYECQKCGKAFICPSSFRGHVNSHHGQK----THACKVCGKTFMYYSYLTR 257

Query: 757 HIRMHMG 763
           H+R H G
Sbjct: 258 HVRTHTG 264



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 3/65 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           S E P+   +C+ C K F   S+L+ H+R HTGE+P+ C  CG  F      + H + H 
Sbjct: 347 SGEKPY---ECKECGKAFRYPSSLRAHMRMHTGEKPYVCKQCGKAFGCPTYFRRHVKTHS 403

Query: 472 EKYPH 476
              P+
Sbjct: 404 GVKPY 408



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 17/57 (29%), Positives = 29/57 (50%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F   S+ + H+ SH G++   C +CG  F     L  H + H  + P+
Sbjct: 212 YECQKCGKAFICPSSFRGHVNSHHGQKTHACKVCGKTFMYYSYLTRHVRTHTGEKPY 268



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 15/36 (41%), Positives = 21/36 (58%)

Query: 1118 CGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTK 1153
            CG+T S  + L +H+   T  KP  CT CG+AF  +
Sbjct: 119  CGETLSQTANLLVHKSYPTEAKPSECTKCGKAFENR 154


>gi|21699060 zinc finger protein 564 [Homo sapiens]
          Length = 553

 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 62/197 (31%), Positives = 88/197 (44%), Gaps = 20/197 (10%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C VCG+ F   S +  H R+HT E+P+ C  C +  S+  N++ H  TH   E P +  +
Sbjct: 311  CKVCGRAFIFPSYVRKHERTHTGEKPYECNKCGKTFSSSSNVRTHERTHT-GEKPYECKE 369

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP-- 1096
               A          + S    MIK   +G  K    G     P+  Q+     T   P  
Sbjct: 370  CGKAF-------ISLPSVRRHMIKHTGDGPYKCQVCGRAFDCPSSFQIHERTHTGEKPYE 422

Query: 1097 ----GLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTIC 1146
                G A +     R+    H       CQ CGK F   S+++ HERTHTGEKP+ C  C
Sbjct: 423  CQVCGKAFISLKRIRKHMILHTGDGPYKCQVCGKAFDCPSSVRTHERTHTGEKPYECKEC 482

Query: 1147 GRAFTTKGNLKVHMGTH 1163
            G+AF    ++++H  TH
Sbjct: 483  GKAFNYASSIRIHERTH 499



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 49/185 (26%), Positives = 79/185 (42%), Gaps = 52/185 (28%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C VCG+ F C S+ +IH R+HT E+P+ C +C +   ++  +++H++ H           
Sbjct: 395  CQVCGRAFDCPSSFQIHERTHTGEKPYECQVCGKAFISLKRIRKHMILHT---------- 444

Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098
                                       +G  K    G+    P+ V+      T      
Sbjct: 445  --------------------------GDGPYKCQVCGKAFDCPSSVRTHERTHT------ 472

Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158
                        K + C+ CGK F+ AS+++IHERTHTGEKP+ C  CG+ F+   + + 
Sbjct: 473  ----------GEKPYECKECGKAFNYASSIRIHERTHTGEKPYECKQCGKTFSYSSSFQR 522

Query: 1159 HMGTH 1163
            H   H
Sbjct: 523  HERAH 527



 Score = 89.0 bits (219), Expect = 3e-17
 Identities = 60/194 (30%), Positives = 82/194 (42%), Gaps = 14/194 (7%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F   S   IH R+HT E+P  C  C +   +  N + H++ H   + P +   
Sbjct: 255  CQECGKAFDRPSLFRIHERTHTGEKPHECKQCGKAFISFTNFQSHMIRHT-GDGPYKCK- 312

Query: 1039 PNFALGPSQSTPSLISSAAPTMI---KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095
                 G +   PS +     T       E N  GK  +                P     
Sbjct: 313  ---VCGRAFIFPSYVRKHERTHTGEKPYECNKCGKTFSSSSNVRTHERTHTGEKPYECKE 369

Query: 1096 PGLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149
             G A +  P  RR   +H       CQ CG+ F   S+ QIHERTHTGEKP+ C +CG+A
Sbjct: 370  CGKAFISLPSVRRHMIKHTGDGPYKCQVCGRAFDCPSSFQIHERTHTGEKPYECQVCGKA 429

Query: 1150 FTTKGNLKVHMGTH 1163
            F +   ++ HM  H
Sbjct: 430  FISLKRIRKHMILH 443



 Score = 81.3 bits (199), Expect = 6e-15
 Identities = 64/207 (30%), Positives = 86/207 (41%), Gaps = 30/207 (14%)

Query: 979  CGVCGKPFACKSALEIHYRSHTK----------ERPFVCALCRRGCSTMGNLKQHLLTHR 1028
            C +CGK F   S+L  H RSH            E+P+ C  C +  S+  + ++H  TH 
Sbjct: 105  CSLCGKVFMHHSSLSRHIRSHLGHKPYDYQEYGEKPYKCKQCGKAFSSCQSFRRHERTHT 164

Query: 1029 LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPA 1088
              E P       +A          + S    MIK   +G  K    G+    P+  Q+  
Sbjct: 165  -GEKP-------YACPECGKAFISLPSVRRHMIKHTGDGPYKCQECGKAFDRPSLFQIHE 216

Query: 1089 GPQTVMGP------GLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHT 1136
               T   P        A +  P  +R   +H       CQ CGK F   S  +IHERTHT
Sbjct: 217  RTHTGEKPYECQECAKAFISLPSFQRHMIRHTGDGPYKCQECGKAFDRPSLFRIHERTHT 276

Query: 1137 GEKPFGCTICGRAFTTKGNLKVHMGTH 1163
            GEKP  C  CG+AF +  N + HM  H
Sbjct: 277  GEKPHECKQCGKAFISFTNFQSHMIRH 303



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C +C +   C S+++ H RTHTGE+P++CK CG+AF    +++ H   H  + P   
Sbjct: 448 PYKCQVCGKAFDCPSSVRTHERTHTGEKPYECKECGKAFNYASSIRIHERTHTGEKP--- 504

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   Q+H R H G
Sbjct: 505 -YECKQCGKTFSYSSSFQRHERAHNG 529



 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 30/86 (34%), Positives = 49/86 (56%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C +C R   C S+ ++H RTHTGE+P++C++CG+AF +   ++ H  +H    P   
Sbjct: 392 PYKCQVCGRAFDCPSSFQIHERTHTGEKPYECQVCGKAFISLKRIRKHMILHTGDGP--- 448

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C +C K F     ++ H R H G
Sbjct: 449 -YKCQVCGKAFDCPSSVRTHERTHTG 473



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C +C R     S ++ H RTHTGE+P++C  CG+ F++  N++TH   H  + P   
Sbjct: 308 PYKCKVCGRAFIFPSYVRKHERTHTGEKPYECNKCGKTFSSSSNVRTHERTHTGEKP--- 364

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F +   +++H+  H G
Sbjct: 365 -YECKECGKAFISLPSVRRHMIKHTG 389



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S  S ++ H RTHTGE+P++CK CG+AF +  +++ H   H    P   
Sbjct: 336 PYECNKCGKTFSSSSNVRTHERTHTGEKPYECKECGKAFISLPSVRRHMIKHTGDGP--- 392

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C +C + F      Q H R H G
Sbjct: 393 -YKCQVCGRAFDCPSSFQIHERTHTG 417



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 38/128 (29%), Positives = 65/128 (50%), Gaps = 19/128 (14%)

Query: 651 GLLDSMQTSETSKL--QQLVENIDKKMTD---PNQCVICHRVLSCQSALKMHYRTHTG-- 703
           GL +S +  +  +   Q L  N++KK+     P +C +C +V    S+L  H R+H G  
Sbjct: 70  GLSESKEYDQCGEAFSQILNLNLNKKIPTIVRPCECSLCGKVFMHHSSLSRHIRSHLGHK 129

Query: 704 --------ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQ 755
                   E+P+KCK CG+AF++  + + H   H  + P    ++CP C K F +   ++
Sbjct: 130 PYDYQEYGEKPYKCKQCGKAFSSCQSFRRHERTHTGEKP----YACPECGKAFISLPSVR 185

Query: 756 QHIRMHMG 763
           +H+  H G
Sbjct: 186 RHMIKHTG 193



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +     S  ++H RTHTGE+P +CK CG+AF +  N ++H   H    P   
Sbjct: 252 PYKCQECGKAFDRPSLFRIHERTHTGEKPHECKQCGKAFISFTNFQSHMIRHTGDGP--- 308

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C +C + F     +++H R H G
Sbjct: 309 -YKCKVCGRAFIFPSYVRKHERTHTG 333



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  S   + + H RTHTGE+P+ C  CG+AF +  +++ H   H    P   
Sbjct: 140 PYKCKQCGKAFSSCQSFRRHERTHTGEKPYACPECGKAFISLPSVRRHMIKHTGDGP--- 196

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F    + Q H R H G
Sbjct: 197 -YKCQECGKAFDRPSLFQIHERTHTG 221



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +      +++ H   HTG+ P+KC++CGRAF    + + H   H  + P   
Sbjct: 364 PYECKECGKAFISLPSVRRHMIKHTGDGPYKCQVCGRAFDCPSSFQIHERTHTGEKP--- 420

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C +C K F +   +++H+ +H G
Sbjct: 421 -YECQVCGKAFISLKRIRKHMILHTG 445



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 3/78 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P +V   E   + E P+   +C+ C K F   S+++IH R+HTGE+P++C  CG  FS  
Sbjct: 461 PSSVRTHERTHTGEKPY---ECKECGKAFNYASSIRIHERTHTGEKPYECKQCGKTFSYS 517

Query: 461 GNLKVHFQRHKEKYPHIQ 478
            + + H + H    P+++
Sbjct: 518 SSFQRHERAHNGDKPYVK 535



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P++C  C +     +  + H   HTG+ P+KCK+CGRAF     ++ H   H  + P   
Sbjct: 280 PHECKQCGKAFISFTNFQSHMIRHTGDGPYKCKVCGRAFIFPSYVRKHERTHTGEKP--- 336

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+++  ++ H R H G
Sbjct: 337 -YECNKCGKTFSSSSNVRTHERTHTG 361



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 22/57 (38%), Positives = 37/57 (64%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C + F   S ++ H R+HTGE+P++CN CG  FS+  N++ H + H  + P+
Sbjct: 309 YKCKVCGRAFIFPSYVRKHERTHTGEKPYECNKCGKTFSSSSNVRTHERTHTGEKPY 365



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 20/57 (35%), Positives = 37/57 (64%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   S+++ H R+HTGE+P++C  CG  F+   ++++H + H  + P+
Sbjct: 449 YKCQVCGKAFDCPSSVRTHERTHTGEKPYECKECGKAFNYASSIRIHERTHTGEKPY 505



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +     S  ++H RTHTGE+P++C+ C +AF +  + + H   H    P   
Sbjct: 196 PYKCQECGKAFDRPSLFQIHERTHTGEKPYECQECAKAFISLPSFQRHMIRHTGDGP--- 252

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F    + + H R H G
Sbjct: 253 -YKCQECGKAFDRPSLFRIHERTHTG 277



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 3/75 (4%)

Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKG 461
           P+V     K + + P+   KC+ C + F   S+ QIH R+HTGE+P++C +CG  F +  
Sbjct: 378 PSVRRHMIKHTGDGPY---KCQVCGRAFDCPSSFQIHERTHTGEKPYECQVCGKAFISLK 434

Query: 462 NLKVHFQRHKEKYPH 476
            ++ H   H    P+
Sbjct: 435 RIRKHMILHTGDGPY 449



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +      + + H   HTG+ P+KC+ CG+AF      + H   H  + P   
Sbjct: 224 PYECQECAKAFISLPSFQRHMIRHTGDGPYKCQECGKAFDRPSLFRIHERTHTGEKP--- 280

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            H C  C K F +    Q H+  H G
Sbjct: 281 -HECKQCGKAFISFTNFQSHMIRHTG 305



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 20/57 (35%), Positives = 34/57 (59%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734
           P +C  C +  +  S++++H RTHTGE+P++CK CG+ F+   + + H   H    P
Sbjct: 476 PYECKECGKAFNYASSIRIHERTHTGEKPYECKQCGKTFSYSSSFQRHERAHNGDKP 532



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 23/57 (40%), Positives = 32/57 (56%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   S  +IH R+HTGE+P +C  CG  F +  N + H  RH    P+
Sbjct: 253 YKCQECGKAFDRPSLFRIHERTHTGEKPHECKQCGKAFISFTNFQSHMIRHTGDGPY 309



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 3/77 (3%)

Query: 400 KPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFST 459
           +P    + E   + E P+   +C+ CAK F S  + Q H+  HTG+ P+KC  CG  F  
Sbjct: 208 RPSLFQIHERTHTGEKPY---ECQECAKAFISLPSFQRHMIRHTGDGPYKCQECGKAFDR 264

Query: 460 KGNLKVHFQRHKEKYPH 476
               ++H + H  + PH
Sbjct: 265 PSLFRIHERTHTGEKPH 281



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 3/74 (4%)

Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462
           NV   E   + E P+   +C+ C K F S  +++ H+  HTG+ P+KC +CG  F    +
Sbjct: 351 NVRTHERTHTGEKPY---ECKECGKAFISLPSVRRHMIKHTGDGPYKCQVCGRAFDCPSS 407

Query: 463 LKVHFQRHKEKYPH 476
            ++H + H  + P+
Sbjct: 408 FQIHERTHTGEKPY 421



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKG 461
           P+V     K + + P+   KC+ C K F   S  QIH R+HTGE+P++C  C   F +  
Sbjct: 182 PSVRRHMIKHTGDGPY---KCQECGKAFDRPSLFQIHERTHTGEKPYECQECAKAFISLP 238

Query: 462 NLKVHFQRHKEKYPH 476
           + + H  RH    P+
Sbjct: 239 SFQRHMIRHTGDGPY 253



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P  V   E   + E P+   +C  C K F S S ++ H R+HTGE+P++C  CG  F + 
Sbjct: 321 PSYVRKHERTHTGEKPY---ECNKCGKTFSSSSNVRTHERTHTGEKPYECKECGKAFISL 377

Query: 461 GNLKVHFQRHKEKYPH 476
            +++ H  +H    P+
Sbjct: 378 PSVRRHMIKHTGDGPY 393



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +      +++ H   HTG+ P+KC+ CG+AF      + H   H  + P   
Sbjct: 168 PYACPECGKAFISLPSVRRHMIKHTGDGPYKCQECGKAFDRPSLFQIHERTHTGEKP--- 224

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F +    Q+H+  H G
Sbjct: 225 -YECQECAKAFISLPSFQRHMIRHTG 249



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 3/76 (3%)

Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           P +  + E   + E P+   +C+ C K F S   ++ H+  HTG+ P+KC +CG  F   
Sbjct: 405 PSSFQIHERTHTGEKPY---ECQVCGKAFISLKRIRKHMILHTGDGPYKCQVCGKAFDCP 461

Query: 461 GNLKVHFQRHKEKYPH 476
            +++ H + H  + P+
Sbjct: 462 SSVRTHERTHTGEKPY 477



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)

Query: 400 KPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFST 459
           +P    + E   + E P   H+C+ C K F S +  Q H+  HTG+ P+KC +CG  F  
Sbjct: 264 RPSLFRIHERTHTGEKP---HECKQCGKAFISFTNFQSHMIRHTGDGPYKCKVCGRAFIF 320

Query: 460 KGNLKVHFQRHKEKYPH 476
              ++ H + H  + P+
Sbjct: 321 PSYVRKHERTHTGEKPY 337



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 20/57 (35%), Positives = 33/57 (57%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F S  + + H R+HTGE+P+ C  CG  F +  +++ H  +H    P+
Sbjct: 141 YKCKQCGKAFSSCQSFRRHERTHTGEKPYACPECGKAFISLPSVRRHMIKHTGDGPY 197



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 28/76 (36%), Positives = 37/76 (48%), Gaps = 16/76 (21%)

Query: 421 KCRFCAKVFGSDSALQIHLRSHT----------GERPFKCNICGNRFSTKGNLKVHFQRH 470
           +C  C KVF   S+L  H+RSH           GE+P+KC  CG  FS+  +    F+RH
Sbjct: 104 ECSLCGKVFMHHSSLSRHIRSHLGHKPYDYQEYGEKPYKCKQCGKAFSSCQS----FRRH 159

Query: 471 KEKYPHIQMNPYPVPE 486
           +    H    PY  PE
Sbjct: 160 ER--THTGEKPYACPE 173



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 18/57 (31%), Positives = 30/57 (52%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           + C  C K F S  +++ H+  HTG+ P+KC  CG  F      ++H + H  + P+
Sbjct: 169 YACPECGKAFISLPSVRRHMIKHTGDGPYKCQECGKAFDRPSLFQIHERTHTGEKPY 225



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 24/103 (23%), Positives = 44/103 (42%), Gaps = 6/103 (5%)

Query: 667 LVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHF 726
           L  ++++ +++  +   C    S    L ++ +  T  RP +C +CG+ F    +L  H 
Sbjct: 63  LRNHMEEGLSESKEYDQCGEAFSQILNLNLNKKIPTIVRPCECSLCGKVFMHHSSLSRHI 122

Query: 727 GVHRAKPPLRVQ------HSCPICQKKFTNAVVLQQHIRMHMG 763
             H    P   Q      + C  C K F++    ++H R H G
Sbjct: 123 RSHLGHKPYDYQEYGEKPYKCKQCGKAFSSCQSFRRHERTHTG 165



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460
           ++ + E   + E P+   +C+ C K F   S+ Q H R+H G++P+  N+    F T+
Sbjct: 491 SIRIHERTHTGEKPY---ECKQCGKTFSYSSSFQRHERAHNGDKPYVKNVGKLSFITQ 545



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 14/47 (29%), Positives = 27/47 (57%)

Query: 1118 CGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHM 1164
            CG+ FS    L ++++  T  +P  C++CG+ F    +L  H+ +H+
Sbjct: 80   CGEAFSQILNLNLNKKIPTIVRPCECSLCGKVFMHHSSLSRHIRSHL 126



 Score = 32.0 bits (71), Expect = 4.0
 Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 6/70 (8%)

Query: 425 CAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPV 484
           C + F     L ++ +  T  RP +C++CG  F    +L  H +       H+   PY  
Sbjct: 80  CGEAFSQILNLNLNKKIPTIVRPCECSLCGKVFMHHSSLSRHIR------SHLGHKPYDY 133

Query: 485 PEYLDNVPTC 494
            EY +    C
Sbjct: 134 QEYGEKPYKC 143



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 12/42 (28%), Positives = 22/42 (52%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTK 719
           P +C  C +  S  S+ + H R H G++P+   +   +F T+
Sbjct: 504 PYECKQCGKTFSYSSSFQRHERAHNGDKPYVKNVGKLSFITQ 545



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 11/28 (39%), Positives = 18/28 (64%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFV 1006
            C  CGK F+  S+ + H R+H  ++P+V
Sbjct: 507  CKQCGKTFSYSSSFQRHERAHNGDKPYV 534


>gi|153791350 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 73/221 (33%), Positives = 93/221 (42%), Gaps = 27/221 (12%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037
            C  CGK F  K  L  H R HT ERP  C  C +  +    L  H   H   K  P +  
Sbjct: 238  CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 297

Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMAL-GEGPP-LPAGVQVPAGPQTVMG 1095
               F     +  P+L+S +     K+     G A A  G G P LPAG Q  A   T   
Sbjct: 298  GRRF-----RHKPNLLSHS-----KIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAV 347

Query: 1096 PGLAPMLAPPPRRTPKQ-----------HNCQSCGKTFSSASALQIHERTHTGEKPFGCT 1144
            P L P   PPP   P+            ++C  CG++F     L+ H+R HTGE+PF C 
Sbjct: 348  P-LKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCA 406

Query: 1145 ICGRAFTTKGNLKVHMGTHMWNN--APARRGRRLSVENPMA 1183
             CG+ F  K +L  H   H      A    GRR S  + +A
Sbjct: 407  ECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA 447



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 101/386 (26%), Positives = 134/386 (34%), Gaps = 59/386 (15%)

Query: 382 ATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRS 441
           A A AL P       R    P V+   P   A D  F+  C  C K F     L  H R 
Sbjct: 207 AAAKALGP-------RPRGRPAVTAPRPGGDAVDRPFQ--CACCGKRFRHKPNLIAHRRV 257

Query: 442 HTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGM 501
           HTGERP +C  CG RF+ K  L  H + H  + P+                         
Sbjct: 258 HTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPY------------------------- 292

Query: 502 SLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASS 561
              P K        KP L        L        + G   S  A P   SPQ P+    
Sbjct: 293 ---PCKECGRRFRHKPNL--------LSHSKIHKRSEG---SAQAAPGPGSPQLPAGPQE 338

Query: 562 ECASLSPGLN---HVESGVSATAESPQSLLGGPP-LTKAEPVSLPCTNARAGDAPVGAQA 617
             A  +P +      E    A  E PQ  +  PP L   +         R   A      
Sbjct: 339 SAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHT 398

Query: 618 SAAPTSVDGAPTSLGSPG-LPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMT 676
              P +      + G    L A S     + PF       + S+ S L       D    
Sbjct: 399 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA--AHRRDHAPD 456

Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736
            P  C  C +    +  L  H R HTGE+P+ C  CG+AF+ K NL +H  +H  + P  
Sbjct: 457 RPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERP-- 514

Query: 737 VQHSCPICQKKFTNAVVLQQHIRMHM 762
             ++CP C + F+    L  H + H+
Sbjct: 515 --YACPDCDRSFSQKSNLITHRKSHI 538



 Score = 84.0 bits (206), Expect = 9e-16
 Identities = 79/274 (28%), Positives = 96/274 (35%), Gaps = 54/274 (19%)

Query: 901  SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960
            S  +   AP  G       P   A E    +PLK      PA  P  G  P       EA
Sbjct: 317  SEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLK------PAQEPPPGAPPEHPQDPIEA 370

Query: 961  PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020
            P SL              C  CG+ F  +  L  H R HT ERPF CA C +        
Sbjct: 371  PPSLYS------------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGK---- 414

Query: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080
            K HL+ H                       S + S        E    G+  + G     
Sbjct: 415  KTHLVAH-----------------------SRVHSGERPFACEEC---GRRFSQGSHLAA 448

Query: 1081 PAGVQVPAGPQTVMGPGLA----PMLAPPPR--RTPKQHNCQSCGKTFSSASALQIHERT 1134
                  P  P      G A    P LA   R     K + C  CGK FS  S L  H R 
Sbjct: 449  HRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRI 508

Query: 1135 HTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168
            HTGE+P+ C  C R+F+ K NL  H  +H+ + A
Sbjct: 509  HTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 542



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 20/229 (8%)

Query: 960  APFSLLFLSRERGKCPST--VCGVCGKPFACKSALEIHYRSHT-KERPFVCALCRRGCST 1016
            APF  L         P     C +CG+ F    AL +H R+H+  +RP  C  C R    
Sbjct: 97   APFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWR 156

Query: 1017 MGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKM-EVNGHGKAMALG 1075
               L+ HL   R    P+    P       +S        A   + + E      A ALG
Sbjct: 157  RKQLRAHL---RRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALG 213

Query: 1076 EGPPLPAGVQVP-AGPQTVMGPGLAPMLAPPPRRTP------------KQHNCQSCGKTF 1122
              P     V  P  G   V  P          R  P            + H C  CGK F
Sbjct: 214  PRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRF 273

Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPAR 1171
            ++   L  H R HTGEKP+ C  CGR F  K NL  H   H  +   A+
Sbjct: 274  TNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 322



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 88/335 (26%), Positives = 114/335 (34%), Gaps = 72/335 (21%)

Query: 445 ERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLP 504
           +RPF+C  CG RF  K NL  H + H  + PH               P C          
Sbjct: 233 DRPFQCACCGKRFRHKPNLIAHRRVHTGERPH-------------QCPECG--------- 270

Query: 505 PEKPVTTWLDSKPVLPTVPT-SVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSEC 563
             K  T    +KP L +      G +  P       +   P+    S+  +R    S   
Sbjct: 271 --KRFT----NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKR----SEGS 320

Query: 564 ASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTS 623
           A  +PG             SPQ L  GP  + AEP   P    +    P        P  
Sbjct: 321 AQAAPGPG-----------SPQ-LPAGPQESAAEPT--PAVPLKPAQEPPPGAPPEHPQD 366

Query: 624 VDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSK----LQQLVENIDKKM---- 675
              AP SL S       +     F     L + Q   T +      +  +N  KK     
Sbjct: 367 PIEAPPSLYS------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVA 420

Query: 676 -------TDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGV 728
                    P  C  C R  S  S L  H R H  +RPF C  CG+AF  K  L  H  +
Sbjct: 421 HSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRI 480

Query: 729 HRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
           H  + P    + CP C K F+    L  H R+H G
Sbjct: 481 HTGEKP----YVCPDCGKAFSQKSNLVSHRRIHTG 511



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 41/122 (33%), Positives = 50/122 (40%), Gaps = 14/122 (11%)

Query: 354 AAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASA 413
           AAPG  SP LP         P P V          PL    +   G PP      P+   
Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAV----------PLKPAQEPPPGAPPE----HPQDPI 368

Query: 414 EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473
           E P   + C  C + F  +  L+ H R HTGERPF C  CG  F  K +L  H + H  +
Sbjct: 369 EAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGE 428

Query: 474 YP 475
            P
Sbjct: 429 RP 430



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 24/162 (14%)

Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375
           AAP P +P     PQ +A+    +    PA  P       PG P    P+     +  P 
Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEP------PPGAP----PEHPQDPIEAPP 372

Query: 376 PLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSAL 435
            L S      +      L  H++           + + E PF    C  C K FG  + L
Sbjct: 373 SLYSCDDCGRSFRLERFLRAHQR-----------QHTGERPF---TCAECGKNFGKKTHL 418

Query: 436 QIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
             H R H+GERPF C  CG RFS   +L  H + H    P +
Sbjct: 419 VAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFV 460



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 1/89 (1%)

Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738
           ++C  C R      AL +H R      P  C  CGR F     L  H  VH A  P  + 
Sbjct: 57  HRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATP-DLG 115

Query: 739 HSCPICQKKFTNAVVLQQHIRMHMGGQIP 767
            +C +C + F   V L  H+R H   + P
Sbjct: 116 FACHLCGQSFRGWVALVLHLRAHSAAKRP 144



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 63/250 (25%), Positives = 77/250 (30%), Gaps = 73/250 (29%)

Query: 294 RPESGASTPGGPAEPSAPAAP---SAAPAPAAP---APAPAPQSAASSQPQSASTPPALA 347
           R E  A    GP  P  PA P   +A P PA P   A  P P +           PP+L 
Sbjct: 316 RSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLY 375

Query: 348 PGSLLGAAPGLPSPLL----------PQTSAS-GVIFPNP--LVSIAATANALDPL---- 390
                G +  L   L           P T A  G  F     LV+ +   +   P     
Sbjct: 376 SCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEE 435

Query: 391 --------SALMKHRKGKPPNVSVFEP---KASAEDPFFK-----------HKCRFCAKV 428
                   S L  HR+   P+     P   KA    P+             + C  C K 
Sbjct: 436 CGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKA 495

Query: 429 FGSDSALQIHLRSHTGERP----------------------------FKCNICGNRFSTK 460
           F   S L  H R HTGERP                            F C ICG  F  +
Sbjct: 496 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 555

Query: 461 GNLKVHFQRH 470
             L  H ++H
Sbjct: 556 ERLLAHQKKH 565



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 24/157 (15%)

Query: 892  GSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAP 951
            GSP L       A  P P+       + P    PE PQ+     E P S  +    G + 
Sbjct: 328  GSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQD---PIEAPPSLYSCDDCGRSF 384

Query: 952  G-----RAGIKE---EAPFSLLFLSRERGKCPSTV-------------CGVCGKPFACKS 990
                  RA  ++   E PF+     +  GK    V             C  CG+ F+  S
Sbjct: 385  RLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGS 444

Query: 991  ALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
             L  H R H  +RPFVC  C +       L  H   H
Sbjct: 445  HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 481



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHT-GERPFKCNICGNRFSTK 460
           P +++     +A  P     C  C + F    AL +HLR+H+  +RP  C  C  RF  +
Sbjct: 98  PFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRR 157

Query: 461 GNLKVHFQR 469
             L+ H +R
Sbjct: 158 KQLRAHLRR 166



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 21/68 (30%), Positives = 29/68 (42%)

Query: 410 KASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQR 469
           ++ A+ P   H+C  C + F    AL +H R      P  C  CG RF     L +H Q 
Sbjct: 47  QSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQV 106

Query: 470 HKEKYPHI 477
           H    P +
Sbjct: 107 HAAATPDL 114



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%)

Query: 681 CVICHRVLSCQSALKMHYRTHTG-ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           C +C +      AL +H R H+  +RP  C  C R F  +  L+ H  + R  PP     
Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAH--LRRCHPPAPEAR 175

Query: 740 S--CPICQKKFTNAVVLQQHIRMHM 762
              C  C + F     L  H R+H+
Sbjct: 176 PFICGNCGRSFAQWDQLVAHKRVHV 200



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 28/101 (27%), Positives = 35/101 (34%), Gaps = 12/101 (11%)

Query: 1072 MALGEGPPLPAGVQVPAGPQTV---------MGPGLAPMLAPPPRRTPKQHNCQSCGKTF 1122
            +A+G   P          PQT+          G  +A   A  P R    H C  C + F
Sbjct: 10   LAMGLAQPRLLSGPSQESPQTLGKESRGLRQQGTSVAQSGAQAPGRA---HRCAHCRRHF 66

Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
                AL +H R      P  C  CGR F     L +H   H
Sbjct: 67   PGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH 107



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 18/52 (34%), Positives = 24/52 (46%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729
           P  C  C R  S +S L  H ++H  +  F C ICG+ F  +  L  H   H
Sbjct: 514 PYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 16/49 (32%), Positives = 23/49 (46%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
            C  C + F+ KS L  H +SH ++  F CA+C +       L  H   H
Sbjct: 517  CPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 35/125 (28%), Positives = 41/125 (32%), Gaps = 19/125 (15%)

Query: 47  GEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPE------DFPEPSPA 100
           GE    C +C   F        H+R  T          + P P  E        P     
Sbjct: 260 GERPHQCPECGKRFTNKPYLTSHRRIHTG---------EKPYPCKECGRRFRHKPNLLSH 310

Query: 101 SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPA--PPTPA 158
           S   +R+E  A    G    +  A P E  AEP  A P     A  PPP AP   P  P 
Sbjct: 311 SKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPL--KPAQEPPPGAPPEHPQDPI 368

Query: 159 YGAPS 163
              PS
Sbjct: 369 EAPPS 373


>gi|153792539 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 73/221 (33%), Positives = 93/221 (42%), Gaps = 27/221 (12%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037
            C  CGK F  K  L  H R HT ERP  C  C +  +    L  H   H   K  P +  
Sbjct: 238  CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 297

Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMAL-GEGPP-LPAGVQVPAGPQTVMG 1095
               F     +  P+L+S +     K+     G A A  G G P LPAG Q  A   T   
Sbjct: 298  GRRF-----RHKPNLLSHS-----KIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAV 347

Query: 1096 PGLAPMLAPPPRRTPKQ-----------HNCQSCGKTFSSASALQIHERTHTGEKPFGCT 1144
            P L P   PPP   P+            ++C  CG++F     L+ H+R HTGE+PF C 
Sbjct: 348  P-LKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCA 406

Query: 1145 ICGRAFTTKGNLKVHMGTHMWNN--APARRGRRLSVENPMA 1183
             CG+ F  K +L  H   H      A    GRR S  + +A
Sbjct: 407  ECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA 447



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 101/386 (26%), Positives = 134/386 (34%), Gaps = 59/386 (15%)

Query: 382 ATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRS 441
           A A AL P       R    P V+   P   A D  F+  C  C K F     L  H R 
Sbjct: 207 AAAKALGP-------RPRGRPAVTAPRPGGDAVDRPFQ--CACCGKRFRHKPNLIAHRRV 257

Query: 442 HTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGM 501
           HTGERP +C  CG RF+ K  L  H + H  + P+                         
Sbjct: 258 HTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPY------------------------- 292

Query: 502 SLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASS 561
              P K        KP L        L        + G   S  A P   SPQ P+    
Sbjct: 293 ---PCKECGRRFRHKPNL--------LSHSKIHKRSEG---SAQAAPGPGSPQLPAGPQE 338

Query: 562 ECASLSPGLN---HVESGVSATAESPQSLLGGPP-LTKAEPVSLPCTNARAGDAPVGAQA 617
             A  +P +      E    A  E PQ  +  PP L   +         R   A      
Sbjct: 339 SAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHT 398

Query: 618 SAAPTSVDGAPTSLGSPG-LPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMT 676
              P +      + G    L A S     + PF       + S+ S L       D    
Sbjct: 399 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA--AHRRDHAPD 456

Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736
            P  C  C +    +  L  H R HTGE+P+ C  CG+AF+ K NL +H  +H  + P  
Sbjct: 457 RPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERP-- 514

Query: 737 VQHSCPICQKKFTNAVVLQQHIRMHM 762
             ++CP C + F+    L  H + H+
Sbjct: 515 --YACPDCDRSFSQKSNLITHRKSHI 538



 Score = 84.0 bits (206), Expect = 9e-16
 Identities = 79/274 (28%), Positives = 96/274 (35%), Gaps = 54/274 (19%)

Query: 901  SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960
            S  +   AP  G       P   A E    +PLK      PA  P  G  P       EA
Sbjct: 317  SEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLK------PAQEPPPGAPPEHPQDPIEA 370

Query: 961  PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020
            P SL              C  CG+ F  +  L  H R HT ERPF CA C +        
Sbjct: 371  PPSLYS------------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGK---- 414

Query: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080
            K HL+ H                       S + S        E    G+  + G     
Sbjct: 415  KTHLVAH-----------------------SRVHSGERPFACEEC---GRRFSQGSHLAA 448

Query: 1081 PAGVQVPAGPQTVMGPGLA----PMLAPPPR--RTPKQHNCQSCGKTFSSASALQIHERT 1134
                  P  P      G A    P LA   R     K + C  CGK FS  S L  H R 
Sbjct: 449  HRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRI 508

Query: 1135 HTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168
            HTGE+P+ C  C R+F+ K NL  H  +H+ + A
Sbjct: 509  HTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 542



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 20/229 (8%)

Query: 960  APFSLLFLSRERGKCPST--VCGVCGKPFACKSALEIHYRSHT-KERPFVCALCRRGCST 1016
            APF  L         P     C +CG+ F    AL +H R+H+  +RP  C  C R    
Sbjct: 97   APFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWR 156

Query: 1017 MGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKM-EVNGHGKAMALG 1075
               L+ HL   R    P+    P       +S        A   + + E      A ALG
Sbjct: 157  RKQLRAHL---RRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALG 213

Query: 1076 EGPPLPAGVQVP-AGPQTVMGPGLAPMLAPPPRRTP------------KQHNCQSCGKTF 1122
              P     V  P  G   V  P          R  P            + H C  CGK F
Sbjct: 214  PRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRF 273

Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPAR 1171
            ++   L  H R HTGEKP+ C  CGR F  K NL  H   H  +   A+
Sbjct: 274  TNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 322



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 88/335 (26%), Positives = 114/335 (34%), Gaps = 72/335 (21%)

Query: 445 ERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLP 504
           +RPF+C  CG RF  K NL  H + H  + PH               P C          
Sbjct: 233 DRPFQCACCGKRFRHKPNLIAHRRVHTGERPH-------------QCPECG--------- 270

Query: 505 PEKPVTTWLDSKPVLPTVPT-SVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSEC 563
             K  T    +KP L +      G +  P       +   P+    S+  +R    S   
Sbjct: 271 --KRFT----NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKR----SEGS 320

Query: 564 ASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTS 623
           A  +PG             SPQ L  GP  + AEP   P    +    P        P  
Sbjct: 321 AQAAPGPG-----------SPQ-LPAGPQESAAEPT--PAVPLKPAQEPPPGAPPEHPQD 366

Query: 624 VDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSK----LQQLVENIDKKM---- 675
              AP SL S       +     F     L + Q   T +      +  +N  KK     
Sbjct: 367 PIEAPPSLYS------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVA 420

Query: 676 -------TDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGV 728
                    P  C  C R  S  S L  H R H  +RPF C  CG+AF  K  L  H  +
Sbjct: 421 HSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRI 480

Query: 729 HRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
           H  + P    + CP C K F+    L  H R+H G
Sbjct: 481 HTGEKP----YVCPDCGKAFSQKSNLVSHRRIHTG 511



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 41/122 (33%), Positives = 50/122 (40%), Gaps = 14/122 (11%)

Query: 354 AAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASA 413
           AAPG  SP LP         P P V          PL    +   G PP      P+   
Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAV----------PLKPAQEPPPGAPPE----HPQDPI 368

Query: 414 EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473
           E P   + C  C + F  +  L+ H R HTGERPF C  CG  F  K +L  H + H  +
Sbjct: 369 EAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGE 428

Query: 474 YP 475
            P
Sbjct: 429 RP 430



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 24/162 (14%)

Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375
           AAP P +P     PQ +A+    +    PA  P       PG P    P+     +  P 
Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEP------PPGAP----PEHPQDPIEAPP 372

Query: 376 PLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSAL 435
            L S      +      L  H++           + + E PF    C  C K FG  + L
Sbjct: 373 SLYSCDDCGRSFRLERFLRAHQR-----------QHTGERPF---TCAECGKNFGKKTHL 418

Query: 436 QIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
             H R H+GERPF C  CG RFS   +L  H + H    P +
Sbjct: 419 VAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFV 460



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 1/89 (1%)

Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738
           ++C  C R      AL +H R      P  C  CGR F     L  H  VH A  P  + 
Sbjct: 57  HRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATP-DLG 115

Query: 739 HSCPICQKKFTNAVVLQQHIRMHMGGQIP 767
            +C +C + F   V L  H+R H   + P
Sbjct: 116 FACHLCGQSFRGWVALVLHLRAHSAAKRP 144



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 63/250 (25%), Positives = 77/250 (30%), Gaps = 73/250 (29%)

Query: 294 RPESGASTPGGPAEPSAPAAP---SAAPAPAAP---APAPAPQSAASSQPQSASTPPALA 347
           R E  A    GP  P  PA P   +A P PA P   A  P P +           PP+L 
Sbjct: 316 RSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLY 375

Query: 348 PGSLLGAAPGLPSPLL----------PQTSAS-GVIFPNP--LVSIAATANALDPL---- 390
                G +  L   L           P T A  G  F     LV+ +   +   P     
Sbjct: 376 SCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEE 435

Query: 391 --------SALMKHRKGKPPNVSVFEP---KASAEDPFFK-----------HKCRFCAKV 428
                   S L  HR+   P+     P   KA    P+             + C  C K 
Sbjct: 436 CGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKA 495

Query: 429 FGSDSALQIHLRSHTGERP----------------------------FKCNICGNRFSTK 460
           F   S L  H R HTGERP                            F C ICG  F  +
Sbjct: 496 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 555

Query: 461 GNLKVHFQRH 470
             L  H ++H
Sbjct: 556 ERLLAHQKKH 565



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 24/157 (15%)

Query: 892  GSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAP 951
            GSP L       A  P P+       + P    PE PQ+     E P S  +    G + 
Sbjct: 328  GSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQD---PIEAPPSLYSCDDCGRSF 384

Query: 952  G-----RAGIKE---EAPFSLLFLSRERGKCPSTV-------------CGVCGKPFACKS 990
                  RA  ++   E PF+     +  GK    V             C  CG+ F+  S
Sbjct: 385  RLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGS 444

Query: 991  ALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
             L  H R H  +RPFVC  C +       L  H   H
Sbjct: 445  HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 481



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHT-GERPFKCNICGNRFSTK 460
           P +++     +A  P     C  C + F    AL +HLR+H+  +RP  C  C  RF  +
Sbjct: 98  PFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRR 157

Query: 461 GNLKVHFQR 469
             L+ H +R
Sbjct: 158 KQLRAHLRR 166



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 21/68 (30%), Positives = 29/68 (42%)

Query: 410 KASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQR 469
           ++ A+ P   H+C  C + F    AL +H R      P  C  CG RF     L +H Q 
Sbjct: 47  QSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQV 106

Query: 470 HKEKYPHI 477
           H    P +
Sbjct: 107 HAAATPDL 114



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%)

Query: 681 CVICHRVLSCQSALKMHYRTHTG-ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           C +C +      AL +H R H+  +RP  C  C R F  +  L+ H  + R  PP     
Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAH--LRRCHPPAPEAR 175

Query: 740 S--CPICQKKFTNAVVLQQHIRMHM 762
              C  C + F     L  H R+H+
Sbjct: 176 PFICGNCGRSFAQWDQLVAHKRVHV 200



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 28/101 (27%), Positives = 35/101 (34%), Gaps = 12/101 (11%)

Query: 1072 MALGEGPPLPAGVQVPAGPQTV---------MGPGLAPMLAPPPRRTPKQHNCQSCGKTF 1122
            +A+G   P          PQT+          G  +A   A  P R    H C  C + F
Sbjct: 10   LAMGLAQPRLLSGPSQESPQTLGKESRGLRQQGTSVAQSGAQAPGRA---HRCAHCRRHF 66

Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
                AL +H R      P  C  CGR F     L +H   H
Sbjct: 67   PGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH 107



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 18/52 (34%), Positives = 24/52 (46%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729
           P  C  C R  S +S L  H ++H  +  F C ICG+ F  +  L  H   H
Sbjct: 514 PYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 16/49 (32%), Positives = 23/49 (46%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
            C  C + F+ KS L  H +SH ++  F CA+C +       L  H   H
Sbjct: 517  CPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 35/125 (28%), Positives = 41/125 (32%), Gaps = 19/125 (15%)

Query: 47  GEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPE------DFPEPSPA 100
           GE    C +C   F        H+R  T          + P P  E        P     
Sbjct: 260 GERPHQCPECGKRFTNKPYLTSHRRIHTG---------EKPYPCKECGRRFRHKPNLLSH 310

Query: 101 SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPA--PPTPA 158
           S   +R+E  A    G    +  A P E  AEP  A P     A  PPP AP   P  P 
Sbjct: 311 SKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPL--KPAQEPPPGAPPEHPQDPI 368

Query: 159 YGAPS 163
              PS
Sbjct: 369 EAPPS 373


>gi|153792647 replication initiator 1 isoform 3 [Homo sapiens]
          Length = 624

 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 73/221 (33%), Positives = 93/221 (42%), Gaps = 27/221 (12%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037
            C  CGK F  K  L  H R HT ERP  C  C +  +    L  H   H   K  P +  
Sbjct: 295  CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 354

Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMAL-GEGPP-LPAGVQVPAGPQTVMG 1095
               F     +  P+L+S +     K+     G A A  G G P LPAG Q  A   T   
Sbjct: 355  GRRF-----RHKPNLLSHS-----KIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAV 404

Query: 1096 PGLAPMLAPPPRRTPKQ-----------HNCQSCGKTFSSASALQIHERTHTGEKPFGCT 1144
            P L P   PPP   P+            ++C  CG++F     L+ H+R HTGE+PF C 
Sbjct: 405  P-LKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCA 463

Query: 1145 ICGRAFTTKGNLKVHMGTHMWNN--APARRGRRLSVENPMA 1183
             CG+ F  K +L  H   H      A    GRR S  + +A
Sbjct: 464  ECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA 504



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 101/386 (26%), Positives = 134/386 (34%), Gaps = 59/386 (15%)

Query: 382 ATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRS 441
           A A AL P       R    P V+   P   A D  F+  C  C K F     L  H R 
Sbjct: 264 AAAKALGP-------RPRGRPAVTAPRPGGDAVDRPFQ--CACCGKRFRHKPNLIAHRRV 314

Query: 442 HTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGM 501
           HTGERP +C  CG RF+ K  L  H + H  + P+                         
Sbjct: 315 HTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPY------------------------- 349

Query: 502 SLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASS 561
              P K        KP L        L        + G   S  A P   SPQ P+    
Sbjct: 350 ---PCKECGRRFRHKPNL--------LSHSKIHKRSEG---SAQAAPGPGSPQLPAGPQE 395

Query: 562 ECASLSPGLN---HVESGVSATAESPQSLLGGPP-LTKAEPVSLPCTNARAGDAPVGAQA 617
             A  +P +      E    A  E PQ  +  PP L   +         R   A      
Sbjct: 396 SAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHT 455

Query: 618 SAAPTSVDGAPTSLGSPG-LPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMT 676
              P +      + G    L A S     + PF       + S+ S L       D    
Sbjct: 456 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA--AHRRDHAPD 513

Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736
            P  C  C +    +  L  H R HTGE+P+ C  CG+AF+ K NL +H  +H  + P  
Sbjct: 514 RPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERP-- 571

Query: 737 VQHSCPICQKKFTNAVVLQQHIRMHM 762
             ++CP C + F+    L  H + H+
Sbjct: 572 --YACPDCDRSFSQKSNLITHRKSHI 595



 Score = 84.0 bits (206), Expect = 9e-16
 Identities = 79/274 (28%), Positives = 96/274 (35%), Gaps = 54/274 (19%)

Query: 901  SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960
            S  +   AP  G       P   A E    +PLK      PA  P  G  P       EA
Sbjct: 374  SEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLK------PAQEPPPGAPPEHPQDPIEA 427

Query: 961  PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020
            P SL              C  CG+ F  +  L  H R HT ERPF CA C +        
Sbjct: 428  PPSLYS------------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGK---- 471

Query: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080
            K HL+ H                       S + S        E    G+  + G     
Sbjct: 472  KTHLVAH-----------------------SRVHSGERPFACEEC---GRRFSQGSHLAA 505

Query: 1081 PAGVQVPAGPQTVMGPGLA----PMLAPPPR--RTPKQHNCQSCGKTFSSASALQIHERT 1134
                  P  P      G A    P LA   R     K + C  CGK FS  S L  H R 
Sbjct: 506  HRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRI 565

Query: 1135 HTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168
            HTGE+P+ C  C R+F+ K NL  H  +H+ + A
Sbjct: 566  HTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 599



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 20/229 (8%)

Query: 960  APFSLLFLSRERGKCPST--VCGVCGKPFACKSALEIHYRSHT-KERPFVCALCRRGCST 1016
            APF  L         P     C +CG+ F    AL +H R+H+  +RP  C  C R    
Sbjct: 154  APFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWR 213

Query: 1017 MGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKM-EVNGHGKAMALG 1075
               L+ HL   R    P+    P       +S        A   + + E      A ALG
Sbjct: 214  RKQLRAHL---RRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALG 270

Query: 1076 EGPPLPAGVQVP-AGPQTVMGPGLAPMLAPPPRRTP------------KQHNCQSCGKTF 1122
              P     V  P  G   V  P          R  P            + H C  CGK F
Sbjct: 271  PRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRF 330

Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPAR 1171
            ++   L  H R HTGEKP+ C  CGR F  K NL  H   H  +   A+
Sbjct: 331  TNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 379



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 88/335 (26%), Positives = 114/335 (34%), Gaps = 72/335 (21%)

Query: 445 ERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLP 504
           +RPF+C  CG RF  K NL  H + H  + PH               P C          
Sbjct: 290 DRPFQCACCGKRFRHKPNLIAHRRVHTGERPH-------------QCPECG--------- 327

Query: 505 PEKPVTTWLDSKPVLPTVPT-SVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSEC 563
             K  T    +KP L +      G +  P       +   P+    S+  +R    S   
Sbjct: 328 --KRFT----NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKR----SEGS 377

Query: 564 ASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTS 623
           A  +PG             SPQ L  GP  + AEP   P    +    P        P  
Sbjct: 378 AQAAPGPG-----------SPQ-LPAGPQESAAEPT--PAVPLKPAQEPPPGAPPEHPQD 423

Query: 624 VDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSK----LQQLVENIDKKM---- 675
              AP SL S       +     F     L + Q   T +      +  +N  KK     
Sbjct: 424 PIEAPPSLYS------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVA 477

Query: 676 -------TDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGV 728
                    P  C  C R  S  S L  H R H  +RPF C  CG+AF  K  L  H  +
Sbjct: 478 HSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRI 537

Query: 729 HRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
           H  + P    + CP C K F+    L  H R+H G
Sbjct: 538 HTGEKP----YVCPDCGKAFSQKSNLVSHRRIHTG 568



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 41/122 (33%), Positives = 50/122 (40%), Gaps = 14/122 (11%)

Query: 354 AAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASA 413
           AAPG  SP LP         P P V          PL    +   G PP      P+   
Sbjct: 380 AAPGPGSPQLPAGPQESAAEPTPAV----------PLKPAQEPPPGAPPE----HPQDPI 425

Query: 414 EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473
           E P   + C  C + F  +  L+ H R HTGERPF C  CG  F  K +L  H + H  +
Sbjct: 426 EAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGE 485

Query: 474 YP 475
            P
Sbjct: 486 RP 487



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 24/162 (14%)

Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375
           AAP P +P     PQ +A+    +    PA  P       PG P    P+     +  P 
Sbjct: 380 AAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEP------PPGAP----PEHPQDPIEAPP 429

Query: 376 PLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSAL 435
            L S      +      L  H++           + + E PF    C  C K FG  + L
Sbjct: 430 SLYSCDDCGRSFRLERFLRAHQR-----------QHTGERPF---TCAECGKNFGKKTHL 475

Query: 436 QIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
             H R H+GERPF C  CG RFS   +L  H + H    P +
Sbjct: 476 VAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFV 517



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 1/89 (1%)

Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738
           ++C  C R      AL +H R      P  C  CGR F     L  H  VH A  P  + 
Sbjct: 114 HRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATP-DLG 172

Query: 739 HSCPICQKKFTNAVVLQQHIRMHMGGQIP 767
            +C +C + F   V L  H+R H   + P
Sbjct: 173 FACHLCGQSFRGWVALVLHLRAHSAAKRP 201



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 63/250 (25%), Positives = 77/250 (30%), Gaps = 73/250 (29%)

Query: 294 RPESGASTPGGPAEPSAPAAP---SAAPAPAAP---APAPAPQSAASSQPQSASTPPALA 347
           R E  A    GP  P  PA P   +A P PA P   A  P P +           PP+L 
Sbjct: 373 RSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLY 432

Query: 348 PGSLLGAAPGLPSPLL----------PQTSAS-GVIFPNP--LVSIAATANALDPL---- 390
                G +  L   L           P T A  G  F     LV+ +   +   P     
Sbjct: 433 SCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEE 492

Query: 391 --------SALMKHRKGKPPNVSVFEP---KASAEDPFFK-----------HKCRFCAKV 428
                   S L  HR+   P+     P   KA    P+             + C  C K 
Sbjct: 493 CGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKA 552

Query: 429 FGSDSALQIHLRSHTGERP----------------------------FKCNICGNRFSTK 460
           F   S L  H R HTGERP                            F C ICG  F  +
Sbjct: 553 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 612

Query: 461 GNLKVHFQRH 470
             L  H ++H
Sbjct: 613 ERLLAHQKKH 622



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 24/157 (15%)

Query: 892  GSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAP 951
            GSP L       A  P P+       + P    PE PQ+     E P S  +    G + 
Sbjct: 385  GSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQD---PIEAPPSLYSCDDCGRSF 441

Query: 952  G-----RAGIKE---EAPFSLLFLSRERGKCPSTV-------------CGVCGKPFACKS 990
                  RA  ++   E PF+     +  GK    V             C  CG+ F+  S
Sbjct: 442  RLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGS 501

Query: 991  ALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
             L  H R H  +RPFVC  C +       L  H   H
Sbjct: 502  HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 538



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHT-GERPFKCNICGNRFSTK 460
           P +++     +A  P     C  C + F    AL +HLR+H+  +RP  C  C  RF  +
Sbjct: 155 PFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRR 214

Query: 461 GNLKVHFQR 469
             L+ H +R
Sbjct: 215 KQLRAHLRR 223



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 21/68 (30%), Positives = 29/68 (42%)

Query: 410 KASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQR 469
           ++ A+ P   H+C  C + F    AL +H R      P  C  CG RF     L +H Q 
Sbjct: 104 QSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQV 163

Query: 470 HKEKYPHI 477
           H    P +
Sbjct: 164 HAAATPDL 171



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%)

Query: 681 CVICHRVLSCQSALKMHYRTHTG-ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           C +C +      AL +H R H+  +RP  C  C R F  +  L+ H  + R  PP     
Sbjct: 175 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAH--LRRCHPPAPEAR 232

Query: 740 S--CPICQKKFTNAVVLQQHIRMHM 762
              C  C + F     L  H R+H+
Sbjct: 233 PFICGNCGRSFAQWDQLVAHKRVHV 257



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 34/123 (27%), Positives = 42/123 (34%), Gaps = 13/123 (10%)

Query: 1050 PSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTV---------MGPGLAP 1100
            P L S  A     +E    G  +A+G   P          PQT+          G  +A 
Sbjct: 46   PQLCSLQAEEEPMLERRCRGP-LAMGLAQPRLLSGPSQESPQTLGKESRGLRQQGTSVAQ 104

Query: 1101 MLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHM 1160
              A  P R    H C  C + F    AL +H R      P  C  CGR F     L +H 
Sbjct: 105  SGAQAPGRA---HRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHR 161

Query: 1161 GTH 1163
              H
Sbjct: 162  QVH 164



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 18/52 (34%), Positives = 24/52 (46%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729
           P  C  C R  S +S L  H ++H  +  F C ICG+ F  +  L  H   H
Sbjct: 571 PYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 622



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 16/49 (32%), Positives = 23/49 (46%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
            C  C + F+ KS L  H +SH ++  F CA+C +       L  H   H
Sbjct: 574  CPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 622



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 35/125 (28%), Positives = 41/125 (32%), Gaps = 19/125 (15%)

Query: 47  GEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPE------DFPEPSPA 100
           GE    C +C   F        H+R  T          + P P  E        P     
Sbjct: 317 GERPHQCPECGKRFTNKPYLTSHRRIHTG---------EKPYPCKECGRRFRHKPNLLSH 367

Query: 101 SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPA--PPTPA 158
           S   +R+E  A    G    +  A P E  AEP  A P     A  PPP AP   P  P 
Sbjct: 368 SKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPL--KPAQEPPPGAPPEHPQDPI 425

Query: 159 YGAPS 163
              PS
Sbjct: 426 EAPPS 430


>gi|153791994 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 73/221 (33%), Positives = 93/221 (42%), Gaps = 27/221 (12%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037
            C  CGK F  K  L  H R HT ERP  C  C +  +    L  H   H   K  P +  
Sbjct: 238  CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 297

Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMAL-GEGPP-LPAGVQVPAGPQTVMG 1095
               F     +  P+L+S +     K+     G A A  G G P LPAG Q  A   T   
Sbjct: 298  GRRF-----RHKPNLLSHS-----KIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAV 347

Query: 1096 PGLAPMLAPPPRRTPKQ-----------HNCQSCGKTFSSASALQIHERTHTGEKPFGCT 1144
            P L P   PPP   P+            ++C  CG++F     L+ H+R HTGE+PF C 
Sbjct: 348  P-LKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCA 406

Query: 1145 ICGRAFTTKGNLKVHMGTHMWNN--APARRGRRLSVENPMA 1183
             CG+ F  K +L  H   H      A    GRR S  + +A
Sbjct: 407  ECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA 447



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 101/386 (26%), Positives = 134/386 (34%), Gaps = 59/386 (15%)

Query: 382 ATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRS 441
           A A AL P       R    P V+   P   A D  F+  C  C K F     L  H R 
Sbjct: 207 AAAKALGP-------RPRGRPAVTAPRPGGDAVDRPFQ--CACCGKRFRHKPNLIAHRRV 257

Query: 442 HTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGM 501
           HTGERP +C  CG RF+ K  L  H + H  + P+                         
Sbjct: 258 HTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPY------------------------- 292

Query: 502 SLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASS 561
              P K        KP L        L        + G   S  A P   SPQ P+    
Sbjct: 293 ---PCKECGRRFRHKPNL--------LSHSKIHKRSEG---SAQAAPGPGSPQLPAGPQE 338

Query: 562 ECASLSPGLN---HVESGVSATAESPQSLLGGPP-LTKAEPVSLPCTNARAGDAPVGAQA 617
             A  +P +      E    A  E PQ  +  PP L   +         R   A      
Sbjct: 339 SAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHT 398

Query: 618 SAAPTSVDGAPTSLGSPG-LPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMT 676
              P +      + G    L A S     + PF       + S+ S L       D    
Sbjct: 399 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA--AHRRDHAPD 456

Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736
            P  C  C +    +  L  H R HTGE+P+ C  CG+AF+ K NL +H  +H  + P  
Sbjct: 457 RPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERP-- 514

Query: 737 VQHSCPICQKKFTNAVVLQQHIRMHM 762
             ++CP C + F+    L  H + H+
Sbjct: 515 --YACPDCDRSFSQKSNLITHRKSHI 538



 Score = 84.0 bits (206), Expect = 9e-16
 Identities = 79/274 (28%), Positives = 96/274 (35%), Gaps = 54/274 (19%)

Query: 901  SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960
            S  +   AP  G       P   A E    +PLK      PA  P  G  P       EA
Sbjct: 317  SEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLK------PAQEPPPGAPPEHPQDPIEA 370

Query: 961  PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020
            P SL              C  CG+ F  +  L  H R HT ERPF CA C +        
Sbjct: 371  PPSLYS------------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGK---- 414

Query: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080
            K HL+ H                       S + S        E    G+  + G     
Sbjct: 415  KTHLVAH-----------------------SRVHSGERPFACEEC---GRRFSQGSHLAA 448

Query: 1081 PAGVQVPAGPQTVMGPGLA----PMLAPPPR--RTPKQHNCQSCGKTFSSASALQIHERT 1134
                  P  P      G A    P LA   R     K + C  CGK FS  S L  H R 
Sbjct: 449  HRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRI 508

Query: 1135 HTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168
            HTGE+P+ C  C R+F+ K NL  H  +H+ + A
Sbjct: 509  HTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 542



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 20/229 (8%)

Query: 960  APFSLLFLSRERGKCPST--VCGVCGKPFACKSALEIHYRSHT-KERPFVCALCRRGCST 1016
            APF  L         P     C +CG+ F    AL +H R+H+  +RP  C  C R    
Sbjct: 97   APFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWR 156

Query: 1017 MGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKM-EVNGHGKAMALG 1075
               L+ HL   R    P+    P       +S        A   + + E      A ALG
Sbjct: 157  RKQLRAHL---RRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALG 213

Query: 1076 EGPPLPAGVQVP-AGPQTVMGPGLAPMLAPPPRRTP------------KQHNCQSCGKTF 1122
              P     V  P  G   V  P          R  P            + H C  CGK F
Sbjct: 214  PRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRF 273

Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPAR 1171
            ++   L  H R HTGEKP+ C  CGR F  K NL  H   H  +   A+
Sbjct: 274  TNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 322



 Score = 67.8 bits (164), Expect = 7e-11
 Identities = 88/335 (26%), Positives = 114/335 (34%), Gaps = 72/335 (21%)

Query: 445 ERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLP 504
           +RPF+C  CG RF  K NL  H + H  + PH               P C          
Sbjct: 233 DRPFQCACCGKRFRHKPNLIAHRRVHTGERPH-------------QCPECG--------- 270

Query: 505 PEKPVTTWLDSKPVLPTVPT-SVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSEC 563
             K  T    +KP L +      G +  P       +   P+    S+  +R    S   
Sbjct: 271 --KRFT----NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKR----SEGS 320

Query: 564 ASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTS 623
           A  +PG             SPQ L  GP  + AEP   P    +    P        P  
Sbjct: 321 AQAAPGPG-----------SPQ-LPAGPQESAAEPT--PAVPLKPAQEPPPGAPPEHPQD 366

Query: 624 VDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSK----LQQLVENIDKKM---- 675
              AP SL S       +     F     L + Q   T +      +  +N  KK     
Sbjct: 367 PIEAPPSLYS------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVA 420

Query: 676 -------TDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGV 728
                    P  C  C R  S  S L  H R H  +RPF C  CG+AF  K  L  H  +
Sbjct: 421 HSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRI 480

Query: 729 HRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
           H  + P    + CP C K F+    L  H R+H G
Sbjct: 481 HTGEKP----YVCPDCGKAFSQKSNLVSHRRIHTG 511



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 41/122 (33%), Positives = 50/122 (40%), Gaps = 14/122 (11%)

Query: 354 AAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASA 413
           AAPG  SP LP         P P V          PL    +   G PP      P+   
Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAV----------PLKPAQEPPPGAPPE----HPQDPI 368

Query: 414 EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473
           E P   + C  C + F  +  L+ H R HTGERPF C  CG  F  K +L  H + H  +
Sbjct: 369 EAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGE 428

Query: 474 YP 475
            P
Sbjct: 429 RP 430



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 24/162 (14%)

Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375
           AAP P +P     PQ +A+    +    PA  P       PG P    P+     +  P 
Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEP------PPGAP----PEHPQDPIEAPP 372

Query: 376 PLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSAL 435
            L S      +      L  H++           + + E PF    C  C K FG  + L
Sbjct: 373 SLYSCDDCGRSFRLERFLRAHQR-----------QHTGERPF---TCAECGKNFGKKTHL 418

Query: 436 QIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477
             H R H+GERPF C  CG RFS   +L  H + H    P +
Sbjct: 419 VAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFV 460



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 1/89 (1%)

Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738
           ++C  C R      AL +H R      P  C  CGR F     L  H  VH A  P  + 
Sbjct: 57  HRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATP-DLG 115

Query: 739 HSCPICQKKFTNAVVLQQHIRMHMGGQIP 767
            +C +C + F   V L  H+R H   + P
Sbjct: 116 FACHLCGQSFRGWVALVLHLRAHSAAKRP 144



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 63/250 (25%), Positives = 77/250 (30%), Gaps = 73/250 (29%)

Query: 294 RPESGASTPGGPAEPSAPAAP---SAAPAPAAP---APAPAPQSAASSQPQSASTPPALA 347
           R E  A    GP  P  PA P   +A P PA P   A  P P +           PP+L 
Sbjct: 316 RSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLY 375

Query: 348 PGSLLGAAPGLPSPLL----------PQTSAS-GVIFPNP--LVSIAATANALDPL---- 390
                G +  L   L           P T A  G  F     LV+ +   +   P     
Sbjct: 376 SCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEE 435

Query: 391 --------SALMKHRKGKPPNVSVFEP---KASAEDPFFK-----------HKCRFCAKV 428
                   S L  HR+   P+     P   KA    P+             + C  C K 
Sbjct: 436 CGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKA 495

Query: 429 FGSDSALQIHLRSHTGERP----------------------------FKCNICGNRFSTK 460
           F   S L  H R HTGERP                            F C ICG  F  +
Sbjct: 496 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 555

Query: 461 GNLKVHFQRH 470
             L  H ++H
Sbjct: 556 ERLLAHQKKH 565



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 24/157 (15%)

Query: 892  GSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAP 951
            GSP L       A  P P+       + P    PE PQ+     E P S  +    G + 
Sbjct: 328  GSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQD---PIEAPPSLYSCDDCGRSF 384

Query: 952  G-----RAGIKE---EAPFSLLFLSRERGKCPSTV-------------CGVCGKPFACKS 990
                  RA  ++   E PF+     +  GK    V             C  CG+ F+  S
Sbjct: 385  RLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGS 444

Query: 991  ALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
             L  H R H  +RPFVC  C +       L  H   H
Sbjct: 445  HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 481



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHT-GERPFKCNICGNRFSTK 460
           P +++     +A  P     C  C + F    AL +HLR+H+  +RP  C  C  RF  +
Sbjct: 98  PFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRR 157

Query: 461 GNLKVHFQR 469
             L+ H +R
Sbjct: 158 KQLRAHLRR 166



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 21/68 (30%), Positives = 29/68 (42%)

Query: 410 KASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQR 469
           ++ A+ P   H+C  C + F    AL +H R      P  C  CG RF     L +H Q 
Sbjct: 47  QSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQV 106

Query: 470 HKEKYPHI 477
           H    P +
Sbjct: 107 HAAATPDL 114



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%)

Query: 681 CVICHRVLSCQSALKMHYRTHTG-ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           C +C +      AL +H R H+  +RP  C  C R F  +  L+ H  + R  PP     
Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAH--LRRCHPPAPEAR 175

Query: 740 S--CPICQKKFTNAVVLQQHIRMHM 762
              C  C + F     L  H R+H+
Sbjct: 176 PFICGNCGRSFAQWDQLVAHKRVHV 200



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 28/101 (27%), Positives = 35/101 (34%), Gaps = 12/101 (11%)

Query: 1072 MALGEGPPLPAGVQVPAGPQTV---------MGPGLAPMLAPPPRRTPKQHNCQSCGKTF 1122
            +A+G   P          PQT+          G  +A   A  P R    H C  C + F
Sbjct: 10   LAMGLAQPRLLSGPSQESPQTLGKESRGLRQQGTSVAQSGAQAPGRA---HRCAHCRRHF 66

Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163
                AL +H R      P  C  CGR F     L +H   H
Sbjct: 67   PGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH 107



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 18/52 (34%), Positives = 24/52 (46%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729
           P  C  C R  S +S L  H ++H  +  F C ICG+ F  +  L  H   H
Sbjct: 514 PYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 16/49 (32%), Positives = 23/49 (46%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027
            C  C + F+ KS L  H +SH ++  F CA+C +       L  H   H
Sbjct: 517  CPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565



 Score = 31.2 bits (69), Expect = 6.8
 Identities = 35/125 (28%), Positives = 41/125 (32%), Gaps = 19/125 (15%)

Query: 47  GEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPE------DFPEPSPA 100
           GE    C +C   F        H+R  T          + P P  E        P     
Sbjct: 260 GERPHQCPECGKRFTNKPYLTSHRRIHTG---------EKPYPCKECGRRFRHKPNLLSH 310

Query: 101 SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPA--PPTPA 158
           S   +R+E  A    G    +  A P E  AEP  A P     A  PPP AP   P  P 
Sbjct: 311 SKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPL--KPAQEPPPGAPPEHPQDPI 368

Query: 159 YGAPS 163
              PS
Sbjct: 369 EAPPS 373


>gi|37622343 zinc finger protein 266 [Homo sapiens]
          Length = 549

 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 62/187 (33%), Positives = 84/187 (44%), Gaps = 28/187 (14%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK FA  S L  H R+HT E+PF C  C +  +   NL  HL  H   E P +  +
Sbjct: 382  CKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHT-GEKPFECLE 440

Query: 1039 PNFALGPSQSTPSLIS--SAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP 1096
               A   S S  + +   SA      ME    GKA         P  V +     T    
Sbjct: 441  CGKAFTHSSSLNNHMRTHSAKKPFTCMEC---GKAFKF------PTCVNLHMRIHT---- 487

Query: 1097 GLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNL 1156
                          K + C+ CGK+FS +++ Q+HERTHTGEKP+ C  CG+AF++  + 
Sbjct: 488  ------------GEKPYKCKQCGKSFSYSNSFQLHERTHTGEKPYECKECGKAFSSSSSF 535

Query: 1157 KVHMGTH 1163
            + H   H
Sbjct: 536  RNHERRH 542



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 58/192 (30%), Positives = 82/192 (42%), Gaps = 10/192 (5%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F     L  H ++HT E+P+ C  C R  +    L QH+  H + E P +  +
Sbjct: 242  CKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIH-VGEKPYECKE 300

Query: 1039 PNFAL-GPSQSTPSLISSAAPTMIKMEVNGHG--KAMALGEGPPLPAGVQ----VPAGPQ 1091
               A    SQ T  L +  A    + ++ G     +  L +   +  G++       G  
Sbjct: 301  CGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKA 360

Query: 1092 TVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151
                  L           P  + C+ CGK F+ +S L  H RTHTGEKPF C  CG+AF 
Sbjct: 361  FTQNSDLTKHARTHSGERP--YECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFA 418

Query: 1152 TKGNLKVHMGTH 1163
               NL  H+  H
Sbjct: 419  ISSNLSGHLRIH 430



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 37/103 (35%), Positives = 52/103 (50%), Gaps = 5/103 (4%)

Query: 662 SKLQQLVENIDKKMT-DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720
           ++  QL E++      DP +C IC +     S L  H+R HTG +P+KCK CG+AFT   
Sbjct: 306 TRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKAFTQNS 365

Query: 721 NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
           +L  H   H  + P    + C  C K F  +  L +H R H G
Sbjct: 366 DLTKHARTHSGERP----YECKECGKAFARSSRLSEHTRTHTG 404



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +CV C +  +  S L  H R HTGE+PF+C  CG+AFT   +L  H   H AK P   
Sbjct: 407 PFECVKCGKAFAISSNLSGHLRIHTGEKPFECLECGKAFTHSSSLNNHMRTHSAKKPF-- 464

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
             +C  C K F     +  H+R+H G
Sbjct: 465 --TCMECGKAFKFPTCVNLHMRIHTG 488



 Score = 71.2 bits (173), Expect = 6e-12
 Identities = 33/84 (39%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  +  S L  H RTHTGE+PF+C  CG+AF    NL  H  +H  + P   
Sbjct: 379 PYECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHTGEKPF-- 436

Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761
              C  C K FT++  L  H+R H
Sbjct: 437 --ECLECGKAFTHSSSLNNHMRTH 458



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 24/111 (21%)

Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736
           +P +C  C +  +    L  H +THTGE+P+KCK CGRAFT    L  H  +H  + P  
Sbjct: 238 NPYECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIHVGEKPYE 297

Query: 737 VQH------------------------SCPICQKKFTNAVVLQQHIRMHMG 763
            +                          C IC K F N+  L  H R+H G
Sbjct: 298 CKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTG 348



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  +  S L  H RTH+GERP++CK CG+AF     L  H   H  + P   
Sbjct: 351 PYKCKDCGKAFTQNSDLTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTGEKPF-- 408

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
              C  C K F  +  L  H+R+H G
Sbjct: 409 --ECVKCGKAFAISSNLSGHLRIHTG 432



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +     + L +H  THTG+ P++CK CG+AFT    L  H   H  + P   
Sbjct: 211 PYKCKECGKGFRYSAYLNIHMGTHTGDNPYECKECGKAFTRSCQLTQHRKTHTGEKP--- 267

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C + FT +  L QH+++H+G
Sbjct: 268 -YKCKDCGRAFTVSSCLSQHMKIHVG 292



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C    +  S L  H +THT + PF+CKICG++F     L  HF +H    P   
Sbjct: 295 PYECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKP--- 351

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K FT    L +H R H G
Sbjct: 352 -YKCKDCGKAFTQNSDLTKHARTHSG 376



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 52/193 (26%), Positives = 77/193 (39%), Gaps = 35/193 (18%)

Query: 977  TVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQL 1036
            +V   CGK F+    + +  R+ T E+ F C+   +      +L+ HL TH  + L    
Sbjct: 129  SVFSQCGKAFSLNPDV-VCQRTCTGEKAFDCSDSGKSFINHSHLQGHLRTHNGESLHEW- 186

Query: 1037 FDPNFALGPSQSTPSLISSAAPTMIKMEVNGHG-----KAMALGEGPPLPAGVQVPAGPQ 1091
                      +     I S   T + + +  H      K    G+G    A + +  G  
Sbjct: 187  ---------KECGRGFIHS---TDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTH 234

Query: 1092 TVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151
            T   P                + C+ CGK F+ +  L  H +THTGEKP+ C  CGRAFT
Sbjct: 235  TGDNP----------------YECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFT 278

Query: 1152 TKGNLKVHMGTHM 1164
                L  HM  H+
Sbjct: 279  VSSCLSQHMKIHV 291



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C+ C +     + + +H R HTGE+P+KCK CG++F+   + + H   H  + P   
Sbjct: 463 PFTCMECGKAFKFPTCVNLHMRIHTGEKPYKCKQCGKSFSYSNSFQLHERTHTGEKP--- 519

Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761
            + C  C K F+++   + H R H
Sbjct: 520 -YECKECGKAFSSSSSFRNHERRH 542



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C+ C +  +  S+L  H RTH+ ++PF C  CG+AF     +  H  +H  + P   
Sbjct: 435 PFECLECGKAFTHSSSLNNHMRTHSAKKPFTCMECGKAFKFPTCVNLHMRIHTGEKP--- 491

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   Q H R H G
Sbjct: 492 -YKCKQCGKSFSYSNSFQLHERTHTG 516



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 21/54 (38%), Positives = 36/54 (66%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473
           +KC+ C K F   ++ Q+H R+HTGE+P++C  CG  FS+  + + H +RH ++
Sbjct: 492 YKCKQCGKSFSYSNSFQLHERTHTGEKPYECKECGKAFSSSSSFRNHERRHADE 545



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 4/80 (5%)

Query: 684 CHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPI 743
           C R     + L +  +TH  E+P+KCK CG+ F     L  H G H    P    + C  
Sbjct: 189 CGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDNP----YECKE 244

Query: 744 CQKKFTNAVVLQQHIRMHMG 763
           C K FT +  L QH + H G
Sbjct: 245 CGKAFTRSCQLTQHRKTHTG 264



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 3/65 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           +A+DPF   +C+ C K F + S L  H R HTG +P+KC  CG  F+   +L  H + H 
Sbjct: 319 TAKDPF---ECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKAFTQNSDLTKHARTHS 375

Query: 472 EKYPH 476
            + P+
Sbjct: 376 GERPY 380



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 26/64 (40%), Positives = 35/64 (54%), Gaps = 3/64 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           S E P+   +C+ C K F   S L  H R+HTGE+PF+C  CG  F+   NL  H + H 
Sbjct: 375 SGERPY---ECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHT 431

Query: 472 EKYP 475
            + P
Sbjct: 432 GEKP 435



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 3/65 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           SA+ PF    C  C K F   + + +H+R HTGE+P+KC  CG  FS   + ++H + H 
Sbjct: 459 SAKKPF---TCMECGKAFKFPTCVNLHMRIHTGEKPYKCKQCGKSFSYSNSFQLHERTHT 515

Query: 472 EKYPH 476
            + P+
Sbjct: 516 GEKPY 520



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 27/64 (42%), Positives = 34/64 (53%), Gaps = 3/64 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           + E PF   +C  C K F   S L  HLR HTGE+PF+C  CG  F+   +L  H + H 
Sbjct: 403 TGEKPF---ECVKCGKAFAISSNLSGHLRIHTGEKPFECLECGKAFTHSSSLNNHMRTHS 459

Query: 472 EKYP 475
            K P
Sbjct: 460 AKKP 463



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 22/56 (39%), Positives = 32/56 (57%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475
           +KC+ C K F  +S L  H R+H+GERP++C  CG  F+    L  H + H  + P
Sbjct: 352 YKCKDCGKAFTQNSDLTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTGEKP 407



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 21/55 (38%), Positives = 31/55 (56%)

Query: 1113 HNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNN 1167
            H  + CG+ F  ++ L +  +TH  EKP+ C  CG+ F     L +HMGTH  +N
Sbjct: 184  HEWKECGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDN 238



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 20/56 (35%), Positives = 30/56 (53%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475
           +KC+ C + F   S L  H++ H GE+P++C  CG  F+    L  H + H  K P
Sbjct: 268 YKCKDCGRAFTVSSCLSQHMKIHVGEKPYECKECGIAFTRSSQLTEHLKTHTAKDP 323



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 20/57 (35%), Positives = 31/57 (54%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F     L  H ++HTGE+P+KC  CG  F+    L  H + H  + P+
Sbjct: 240 YECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIHVGEKPY 296



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 20/57 (35%), Positives = 32/57 (56%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   + L IH+ +HTG+ P++C  CG  F+    L  H + H  + P+
Sbjct: 212 YKCKECGKGFRYSAYLNIHMGTHTGDNPYECKECGKAFTRSCQLTQHRKTHTGEKPY 268



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 21/57 (36%), Positives = 30/57 (52%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C   F   S L  HL++HT + PF+C ICG  F     L  HF+ H    P+
Sbjct: 296 YECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPY 352



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 3/65 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           + E PF   +C  C K F   S+L  H+R+H+ ++PF C  CG  F     + +H + H 
Sbjct: 431 TGEKPF---ECLECGKAFTHSSSLNNHMRTHSAKKPFTCMECGKAFKFPTCVNLHMRIHT 487

Query: 472 EKYPH 476
            + P+
Sbjct: 488 GEKPY 492



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 16/57 (28%), Positives = 28/57 (49%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           H+ + C + F   + L + +++H  E+P+KC  CG  F     L +H   H    P+
Sbjct: 184 HEWKECGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDNPY 240



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 20/55 (36%), Positives = 27/55 (49%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           C    K F + S LQ HLR+H GE   +   CG  F    +L V  Q H+ + P+
Sbjct: 158 CSDSGKSFINHSHLQGHLRTHNGESLHEWKECGRGFIHSTDLAVRIQTHRSEKPY 212



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 37/129 (28%), Positives = 52/129 (40%), Gaps = 23/129 (17%)

Query: 654 DSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICG 713
           D +    +S +Q +  +   +++D  QC     V S  S LK H RT   E  F+C + G
Sbjct: 56  DVLGEPTSSGIQMIGSHNGGEVSDVKQC---GDVSSEHSCLKTHVRTQNSENTFECYLYG 112

Query: 714 RAFTTKGNLKTHFGVHRA-----------KPPLRVQHSCP-----ICQ---KKFTNAVVL 754
             F T  + KT  G  R+            P +  Q +C       C    K F N   L
Sbjct: 113 VDFLTL-HKKTSTGEQRSVFSQCGKAFSLNPDVVCQRTCTGEKAFDCSDSGKSFINHSHL 171

Query: 755 QQHIRMHMG 763
           Q H+R H G
Sbjct: 172 QGHLRTHNG 180


>gi|37622349 zinc finger protein 266 [Homo sapiens]
          Length = 549

 Score = 90.5 bits (223), Expect = 9e-18
 Identities = 62/187 (33%), Positives = 84/187 (44%), Gaps = 28/187 (14%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK FA  S L  H R+HT E+PF C  C +  +   NL  HL  H   E P +  +
Sbjct: 382  CKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHT-GEKPFECLE 440

Query: 1039 PNFALGPSQSTPSLIS--SAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP 1096
               A   S S  + +   SA      ME    GKA         P  V +     T    
Sbjct: 441  CGKAFTHSSSLNNHMRTHSAKKPFTCMEC---GKAFKF------PTCVNLHMRIHT---- 487

Query: 1097 GLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNL 1156
                          K + C+ CGK+FS +++ Q+HERTHTGEKP+ C  CG+AF++  + 
Sbjct: 488  ------------GEKPYKCKQCGKSFSYSNSFQLHERTHTGEKPYECKECGKAFSSSSSF 535

Query: 1157 KVHMGTH 1163
            + H   H
Sbjct: 536  RNHERRH 542



 Score = 85.5 bits (210), Expect = 3e-16
 Identities = 58/192 (30%), Positives = 82/192 (42%), Gaps = 10/192 (5%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038
            C  CGK F     L  H ++HT E+P+ C  C R  +    L QH+  H + E P +  +
Sbjct: 242  CKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIH-VGEKPYECKE 300

Query: 1039 PNFAL-GPSQSTPSLISSAAPTMIKMEVNGHG--KAMALGEGPPLPAGVQ----VPAGPQ 1091
               A    SQ T  L +  A    + ++ G     +  L +   +  G++       G  
Sbjct: 301  CGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKA 360

Query: 1092 TVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151
                  L           P  + C+ CGK F+ +S L  H RTHTGEKPF C  CG+AF 
Sbjct: 361  FTQNSDLTKHARTHSGERP--YECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFA 418

Query: 1152 TKGNLKVHMGTH 1163
               NL  H+  H
Sbjct: 419  ISSNLSGHLRIH 430



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 37/103 (35%), Positives = 52/103 (50%), Gaps = 5/103 (4%)

Query: 662 SKLQQLVENIDKKMT-DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720
           ++  QL E++      DP +C IC +     S L  H+R HTG +P+KCK CG+AFT   
Sbjct: 306 TRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKAFTQNS 365

Query: 721 NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
           +L  H   H  + P    + C  C K F  +  L +H R H G
Sbjct: 366 DLTKHARTHSGERP----YECKECGKAFARSSRLSEHTRTHTG 404



 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +CV C +  +  S L  H R HTGE+PF+C  CG+AFT   +L  H   H AK P   
Sbjct: 407 PFECVKCGKAFAISSNLSGHLRIHTGEKPFECLECGKAFTHSSSLNNHMRTHSAKKPF-- 464

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
             +C  C K F     +  H+R+H G
Sbjct: 465 --TCMECGKAFKFPTCVNLHMRIHTG 488



 Score = 71.2 bits (173), Expect = 6e-12
 Identities = 33/84 (39%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  +  S L  H RTHTGE+PF+C  CG+AF    NL  H  +H  + P   
Sbjct: 379 PYECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHTGEKPF-- 436

Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761
              C  C K FT++  L  H+R H
Sbjct: 437 --ECLECGKAFTHSSSLNNHMRTH 458



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 24/111 (21%)

Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736
           +P +C  C +  +    L  H +THTGE+P+KCK CGRAFT    L  H  +H  + P  
Sbjct: 238 NPYECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIHVGEKPYE 297

Query: 737 VQH------------------------SCPICQKKFTNAVVLQQHIRMHMG 763
            +                          C IC K F N+  L  H R+H G
Sbjct: 298 CKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTG 348



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +  +  S L  H RTH+GERP++CK CG+AF     L  H   H  + P   
Sbjct: 351 PYKCKDCGKAFTQNSDLTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTGEKPF-- 408

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
              C  C K F  +  L  H+R+H G
Sbjct: 409 --ECVKCGKAFAISSNLSGHLRIHTG 432



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C +     + L +H  THTG+ P++CK CG+AFT    L  H   H  + P   
Sbjct: 211 PYKCKECGKGFRYSAYLNIHMGTHTGDNPYECKECGKAFTRSCQLTQHRKTHTGEKP--- 267

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C + FT +  L QH+++H+G
Sbjct: 268 -YKCKDCGRAFTVSSCLSQHMKIHVG 292



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C  C    +  S L  H +THT + PF+CKICG++F     L  HF +H    P   
Sbjct: 295 PYECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKP--- 351

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K FT    L +H R H G
Sbjct: 352 -YKCKDCGKAFTQNSDLTKHARTHSG 376



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 52/193 (26%), Positives = 77/193 (39%), Gaps = 35/193 (18%)

Query: 977  TVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQL 1036
            +V   CGK F+    + +  R+ T E+ F C+   +      +L+ HL TH  + L    
Sbjct: 129  SVFSQCGKAFSLNPDV-VCQRTCTGEKAFDCSDSGKSFINHSHLQGHLRTHNGESLHEW- 186

Query: 1037 FDPNFALGPSQSTPSLISSAAPTMIKMEVNGHG-----KAMALGEGPPLPAGVQVPAGPQ 1091
                      +     I S   T + + +  H      K    G+G    A + +  G  
Sbjct: 187  ---------KECGRGFIHS---TDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTH 234

Query: 1092 TVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151
            T   P                + C+ CGK F+ +  L  H +THTGEKP+ C  CGRAFT
Sbjct: 235  TGDNP----------------YECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFT 278

Query: 1152 TKGNLKVHMGTHM 1164
                L  HM  H+
Sbjct: 279  VSSCLSQHMKIHV 291



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C+ C +     + + +H R HTGE+P+KCK CG++F+   + + H   H  + P   
Sbjct: 463 PFTCMECGKAFKFPTCVNLHMRIHTGEKPYKCKQCGKSFSYSNSFQLHERTHTGEKP--- 519

Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761
            + C  C K F+++   + H R H
Sbjct: 520 -YECKECGKAFSSSSSFRNHERRH 542



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P +C+ C +  +  S+L  H RTH+ ++PF C  CG+AF     +  H  +H  + P   
Sbjct: 435 PFECLECGKAFTHSSSLNNHMRTHSAKKPFTCMECGKAFKFPTCVNLHMRIHTGEKP--- 491

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            + C  C K F+ +   Q H R H G
Sbjct: 492 -YKCKQCGKSFSYSNSFQLHERTHTG 516



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 21/54 (38%), Positives = 36/54 (66%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473
           +KC+ C K F   ++ Q+H R+HTGE+P++C  CG  FS+  + + H +RH ++
Sbjct: 492 YKCKQCGKSFSYSNSFQLHERTHTGEKPYECKECGKAFSSSSSFRNHERRHADE 545



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 4/80 (5%)

Query: 684 CHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPI 743
           C R     + L +  +TH  E+P+KCK CG+ F     L  H G H    P    + C  
Sbjct: 189 CGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDNP----YECKE 244

Query: 744 CQKKFTNAVVLQQHIRMHMG 763
           C K FT +  L QH + H G
Sbjct: 245 CGKAFTRSCQLTQHRKTHTG 264



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 3/65 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           +A+DPF   +C+ C K F + S L  H R HTG +P+KC  CG  F+   +L  H + H 
Sbjct: 319 TAKDPF---ECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKAFTQNSDLTKHARTHS 375

Query: 472 EKYPH 476
            + P+
Sbjct: 376 GERPY 380



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 26/64 (40%), Positives = 35/64 (54%), Gaps = 3/64 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           S E P+   +C+ C K F   S L  H R+HTGE+PF+C  CG  F+   NL  H + H 
Sbjct: 375 SGERPY---ECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHT 431

Query: 472 EKYP 475
            + P
Sbjct: 432 GEKP 435



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 3/65 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           SA+ PF    C  C K F   + + +H+R HTGE+P+KC  CG  FS   + ++H + H 
Sbjct: 459 SAKKPF---TCMECGKAFKFPTCVNLHMRIHTGEKPYKCKQCGKSFSYSNSFQLHERTHT 515

Query: 472 EKYPH 476
            + P+
Sbjct: 516 GEKPY 520



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 27/64 (42%), Positives = 34/64 (53%), Gaps = 3/64 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           + E PF   +C  C K F   S L  HLR HTGE+PF+C  CG  F+   +L  H + H 
Sbjct: 403 TGEKPF---ECVKCGKAFAISSNLSGHLRIHTGEKPFECLECGKAFTHSSSLNNHMRTHS 459

Query: 472 EKYP 475
            K P
Sbjct: 460 AKKP 463



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 22/56 (39%), Positives = 32/56 (57%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475
           +KC+ C K F  +S L  H R+H+GERP++C  CG  F+    L  H + H  + P
Sbjct: 352 YKCKDCGKAFTQNSDLTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTGEKP 407



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 21/55 (38%), Positives = 31/55 (56%)

Query: 1113 HNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNN 1167
            H  + CG+ F  ++ L +  +TH  EKP+ C  CG+ F     L +HMGTH  +N
Sbjct: 184  HEWKECGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDN 238



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 20/56 (35%), Positives = 30/56 (53%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475
           +KC+ C + F   S L  H++ H GE+P++C  CG  F+    L  H + H  K P
Sbjct: 268 YKCKDCGRAFTVSSCLSQHMKIHVGEKPYECKECGIAFTRSSQLTEHLKTHTAKDP 323



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 20/57 (35%), Positives = 31/57 (54%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C K F     L  H ++HTGE+P+KC  CG  F+    L  H + H  + P+
Sbjct: 240 YECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIHVGEKPY 296



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 20/57 (35%), Positives = 32/57 (56%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           +KC+ C K F   + L IH+ +HTG+ P++C  CG  F+    L  H + H  + P+
Sbjct: 212 YKCKECGKGFRYSAYLNIHMGTHTGDNPYECKECGKAFTRSCQLTQHRKTHTGEKPY 268



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 21/57 (36%), Positives = 30/57 (52%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           ++C+ C   F   S L  HL++HT + PF+C ICG  F     L  HF+ H    P+
Sbjct: 296 YECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPY 352



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 3/65 (4%)

Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471
           + E PF   +C  C K F   S+L  H+R+H+ ++PF C  CG  F     + +H + H 
Sbjct: 431 TGEKPF---ECLECGKAFTHSSSLNNHMRTHSAKKPFTCMECGKAFKFPTCVNLHMRIHT 487

Query: 472 EKYPH 476
            + P+
Sbjct: 488 GEKPY 492



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 16/57 (28%), Positives = 28/57 (49%)

Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           H+ + C + F   + L + +++H  E+P+KC  CG  F     L +H   H    P+
Sbjct: 184 HEWKECGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDNPY 240



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 20/55 (36%), Positives = 27/55 (49%)

Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476
           C    K F + S LQ HLR+H GE   +   CG  F    +L V  Q H+ + P+
Sbjct: 158 CSDSGKSFINHSHLQGHLRTHNGESLHEWKECGRGFIHSTDLAVRIQTHRSEKPY 212



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 37/129 (28%), Positives = 52/129 (40%), Gaps = 23/129 (17%)

Query: 654 DSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICG 713
           D +    +S +Q +  +   +++D  QC     V S  S LK H RT   E  F+C + G
Sbjct: 56  DVLGEPTSSGIQMIGSHNGGEVSDVKQC---GDVSSEHSCLKTHVRTQNSENTFECYLYG 112

Query: 714 RAFTTKGNLKTHFGVHRA-----------KPPLRVQHSCP-----ICQ---KKFTNAVVL 754
             F T  + KT  G  R+            P +  Q +C       C    K F N   L
Sbjct: 113 VDFLTL-HKKTSTGEQRSVFSQCGKAFSLNPDVVCQRTCTGEKAFDCSDSGKSFINHSHL 171

Query: 755 QQHIRMHMG 763
           Q H+R H G
Sbjct: 172 QGHLRTHNG 180


>gi|13376064 zinc finger protein 408 [Homo sapiens]
          Length = 720

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 92/315 (29%), Positives = 129/315 (40%), Gaps = 63/315 (20%)

Query: 873  DRLSNDSSSAV-----GDLESR---SAGSPALSESSSSQALSPAPSNGESFRSKSPG--- 921
            DR+S DS         GD++      A  P   +S+S+    P  S G SF S + G   
Sbjct: 243  DRISKDSQPLGPLLQDGDVDEECPAQAQMPPELQSNSATQQDPDGS-GASFSSSARGTQP 301

Query: 922  -------LGAPEEPQEIPLKTERPDSPAAAPG----SGGAPGRAGIKEEAPFSLLFLSRE 970
                   L +P +  + P + + P+  A   G    S   PG AG            S +
Sbjct: 302  HGYLAKKLHSPSD--QCPPRAKTPEPGAQQSGFPTLSRSPPGPAGS-----------SPK 348

Query: 971  RGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-L 1029
            +G+     CG CGK F     L+ H   HT  +PF+C  C +  S+  + K H+L HR +
Sbjct: 349  QGR--RYRCGECGKAFLQLCHLKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGV 406

Query: 1030 KELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGV-QVPA 1088
            +  P    D  +          ++ S A      +    GKA A      L     QVPA
Sbjct: 407  RPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQC---GKAFARRPSLRLHRKTHQVPA 463

Query: 1089 GPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGR 1148
             P            AP P        C  CG+  ++  +L+ H R HTGEKPF C  CGR
Sbjct: 464  AP------------APCP--------CPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGR 503

Query: 1149 AFTTKGNLKVHMGTH 1163
            AF  +GNL+ H+  H
Sbjct: 504  AFRQRGNLRGHLRLH 518



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 89/333 (26%), Positives = 127/333 (38%), Gaps = 57/333 (17%)

Query: 885  DLESRSA------GSPALSESSSSQALSP---------APSNGESFRSKSPGLGAPEEPQ 929
            +L+S SA      GS A S SSS++   P         +PS+    R+K+P  GA +   
Sbjct: 274  ELQSNSATQQDPDGSGA-SFSSSARGTQPHGYLAKKLHSPSDQCPPRAKTPEPGAQQSG- 331

Query: 930  EIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRER----GKCPSTVCGVCGKP 985
              P  +  P  PA +    G   R G   +A   L  L +      G  P  +C  CGK 
Sbjct: 332  -FPTLSRSPPGPAGSSPKQGRRYRCGECGKAFLQLCHLKKHAFVHTGHKPF-LCTECGKS 389

Query: 986  FACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLFDPNFALG 1044
            ++ + + + H   H   RPF C  C +   T  +LK+H + H   +          FA  
Sbjct: 390  YSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARR 449

Query: 1045 PSQSTPSLISS--AAPTMIKMEVNGHGKA----------MALGEGP-------------- 1078
            PS           AAP      V G   A          +  GE P              
Sbjct: 450  PSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRG 509

Query: 1079 PLPAGVQVPAGPQTVMGPGLAPMLAPPPR-------RTPKQHNCQSCGKTFSSASALQIH 1131
             L   +++  G +    P  A      P         T + H C  CGK       L+ H
Sbjct: 510  NLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAH 569

Query: 1132 ERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHM 1164
            ER H+GE+PF C  CGRA+T    L+ H+ +H+
Sbjct: 570  ERLHSGERPFPCPQCGRAYTLATKLRRHLKSHL 602



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 36/86 (41%), Positives = 48/86 (55%), Gaps = 4/86 (4%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C +C R L+ Q +L+ H R HTGE+PF C  CGRAF  +GNL+ H  +H  + P R 
Sbjct: 467 PCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYR- 525

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
              CP C   F     L++H+  H G
Sbjct: 526 ---CPHCADAFPQLPELRRHLISHTG 548



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 56/190 (29%), Positives = 83/190 (43%), Gaps = 28/190 (14%)

Query: 974  CPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELP 1033
            CP   C VCG+P A + +L  H R HT E+PF+C  C R     GNL+ HL  H   E P
Sbjct: 468  CP---CPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHT-GERP 523

Query: 1034 SQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTV 1093
             +   P+ A     + P L        ++  +  H      GE    P   +    P T+
Sbjct: 524  YRC--PHCA----DAFPQLPE------LRRHLISH-----TGEAHLCPVCGKALRDPHTL 566

Query: 1094 MGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTK 1153
                    L    R  P    C  CG+ ++ A+ L+ H ++H  +KP+ C  CG  +T  
Sbjct: 567  RAH---ERLHSGERPFP----CPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLP 619

Query: 1154 GNLKVHMGTH 1163
             +L+ H  +H
Sbjct: 620  QSLRRHQLSH 629



 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 1/86 (1%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +    Q  LK H   H+G RPF C  CG+AF  + +L+ H   H+  P    
Sbjct: 408 PFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARRPSLRLHRKTHQV-PAAPA 466

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
              CP+C +   N   L+ H+R+H G
Sbjct: 467 PCPCPVCGRPLANQGSLRNHMRLHTG 492



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 35/108 (32%), Positives = 49/108 (45%), Gaps = 8/108 (7%)

Query: 663 KLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNL 722
           +L +L  ++     + + C +C + L     L+ H R H+GERPF C  CGRA+T    L
Sbjct: 535 QLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTLATKL 594

Query: 723 KTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTP 770
           + H   H    P R    CP C   +T    L Q +R H     P  P
Sbjct: 595 RRHLKSHLEDKPYR----CPTCGMGYT----LPQSLRRHQLSHRPEAP 634



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 5/86 (5%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C R    +  L+ H R HTGERP++C  C  AF     L+ H   H  +     
Sbjct: 495 PFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGE----- 549

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763
            H CP+C K   +   L+ H R+H G
Sbjct: 550 AHLCPVCGKALRDPHTLRAHERLHSG 575



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 7/95 (7%)

Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737
           P  C  C +  S + + K H   H G RPF C  C +A+ T+ +LK H  VH    P   
Sbjct: 380 PFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARPF-- 437

Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLP 772
             +C  C K F     L+ H + H   Q+P  P P
Sbjct: 438 --ACDQCGKAFARRPSLRLHRKTH---QVPAAPAP 467



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 72/303 (23%), Positives = 99/303 (32%), Gaps = 60/303 (19%)

Query: 288 GAQPLSRPESGASTPGGPA------EPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSAS 341
           GA+P +  + G +    P+          PAAP+  P P    P     S  +       
Sbjct: 433 GARPFACDQCGKAFARRPSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLHTG 492

Query: 342 TPPALAP--GSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKG 399
             P L P  G        L   L   T       P+        A+A   L  L +H   
Sbjct: 493 EKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPH-------CADAFPQLPELRRHLIS 545

Query: 400 KPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFST 459
                               H C  C K       L+ H R H+GERPF C  CG  ++ 
Sbjct: 546 HTGEA---------------HLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTL 590

Query: 460 KGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVL 519
              L+ H + H E  P+               PTC G+ Y +   P+      L  +P  
Sbjct: 591 ATKLRRHLKSHLEDKPY-------------RCPTC-GMGYTL---PQSLRRHQLSHRPEA 633

Query: 520 PTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSA 579
           P          PP+VP A   A  P+       PQ       E   +SP  + VE  +S 
Sbjct: 634 PC--------SPPSVPSA---ASEPTVVLLQAEPQLLDTHREE--EVSPARDVVEVTISE 680

Query: 580 TAE 582
           + E
Sbjct: 681 SQE 683



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 4/86 (4%)

Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739
           +C  C +       LK H   HTG +PF C  CG++++++ + K H   HR   P     
Sbjct: 354 RCGECGKAFLQLCHLKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGVRPF---- 409

Query: 740 SCPICQKKFTNAVVLQQHIRMHMGGQ 765
            CP C K +     L++H  +H G +
Sbjct: 410 PCPQCDKAYGTQRDLKEHQVVHSGAR 435



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 21/56 (37%), Positives = 32/56 (57%)

Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPA 1170
            C  C K + +   L+ H+  H+G +PF C  CG+AF  + +L++H  TH    APA
Sbjct: 411  CPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARRPSLRLHRKTHQVPAAPA 466



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 67/287 (23%), Positives = 99/287 (34%), Gaps = 33/287 (11%)

Query: 222 LIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPA 281
           ++ ++ S V      P   +  P   P +  P+  Q   + +  L           S P 
Sbjct: 193 VVTEVESAVQQEVASPGEDAAEPCIDPGSQSPSGIQAENMVSPGLKFPTQDRISKDSQPL 252

Query: 282 APAAFEG-------AQPLSRPE--SGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSA 332
            P   +G       AQ    PE  S ++T   P    A  + SA         A    S 
Sbjct: 253 GPLLQDGDVDEECPAQAQMPPELQSNSATQQDPDGSGASFSSSARGTQPHGYLAKKLHSP 312

Query: 333 ASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSA 392
           +   P  A TP    PG+     P L     P   A                 A   L  
Sbjct: 313 SDQCPPRAKTPE---PGAQQSGFPTLSRS--PPGPAGSSPKQGRRYRCGECGKAFLQLCH 367

Query: 393 LMKH---RKGKPPNVSVFEPKA-SAEDPFFKHK----------CRFCAKVFGSDSALQIH 438
           L KH     G  P +     K+ S+E+ F  H           C  C K +G+   L+ H
Sbjct: 368 LKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEH 427

Query: 439 LRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVP 485
              H+G RPF C+ CG  F+ + +L++H + H+     +   P P P
Sbjct: 428 QVVHSGARPFACDQCGKAFARRPSLRLHRKTHQ-----VPAAPAPCP 469



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 8/83 (9%)

Query: 979  CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLK------EL 1032
            C  CG+ +   + L  H +SH +++P+ C  C  G +   +L++H L+HR +       +
Sbjct: 581  CPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHRPEAPCSPPSV 640

Query: 1033 PSQLFDPNFALGPSQSTPSLISS 1055
            PS   +P   L   Q+ P L+ +
Sbjct: 641  PSAASEPTVVL--LQAEPQLLDT 661



 Score = 34.3 bits (77), Expect = 0.80
 Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 4/59 (6%)

Query: 705 RPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763
           R ++C  CG+AF    +LK H  VH    P      C  C K +++    + H+  H G
Sbjct: 351 RRYRCGECGKAFLQLCHLKKHAFVHTGHKPF----LCTECGKSYSSEESFKAHMLGHRG 405


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,848,018
Number of Sequences: 37866
Number of extensions: 4272017
Number of successful extensions: 134631
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1868
Number of HSP's successfully gapped in prelim test: 2544
Number of HSP's that attempted gapping in prelim test: 27173
Number of HSP's gapped (non-prelim): 75669
length of query: 1300
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1186
effective length of database: 13,930,794
effective search space: 16521921684
effective search space used: 16521921684
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.