BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|154146199 sal-like 3 [Homo sapiens] (1300 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|154146199 sal-like 3 [Homo sapiens] 2630 0.0 gi|118442837 sal-like 1 isoform a [Homo sapiens] 1224 0.0 gi|189217876 sal-like 1 isoform b [Homo sapiens] 1161 0.0 gi|10047144 sal-like 4 [Homo sapiens] 595 e-170 gi|49087132 sal-like 2 [Homo sapiens] 470 e-132 gi|138175817 zinc finger protein 236 [Homo sapiens] 131 4e-30 gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo... 131 5e-30 gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo... 131 5e-30 gi|148276998 zinc finger protein 628 [Homo sapiens] 127 9e-29 gi|69885084 p120E4F [Homo sapiens] 111 4e-24 gi|22749325 zinc finger protein 48 [Homo sapiens] 106 1e-22 gi|116256460 zinc finger protein 775 [Homo sapiens] 104 6e-22 gi|21699088 zinc finger protein 627 [Homo sapiens] 102 3e-21 gi|51173737 ras responsive element binding protein 1 isoform 1 [... 98 5e-20 gi|4507987 zinc finger protein 136 [Homo sapiens] 97 8e-20 gi|21687252 zinc finger protein 296 [Homo sapiens] 96 2e-19 gi|193083160 zinc finger protein 441 [Homo sapiens] 94 7e-19 gi|47271376 zinc finger protein 615 [Homo sapiens] 94 7e-19 gi|224548994 zinc finger protein 709 isoform b [Homo sapiens] 94 8e-19 gi|22749235 zinc finger protein 709 isoform a [Homo sapiens] 94 8e-19 gi|40807465 zinc finger protein 341 [Homo sapiens] 93 1e-18 gi|33438586 zinc finger protein 77 [Homo sapiens] 92 2e-18 gi|21699060 zinc finger protein 564 [Homo sapiens] 92 4e-18 gi|153791350 replication initiator 1 isoform 1 [Homo sapiens] 92 4e-18 gi|153792539 replication initiator 1 isoform 1 [Homo sapiens] 92 4e-18 gi|153792647 replication initiator 1 isoform 3 [Homo sapiens] 92 4e-18 gi|153791994 replication initiator 1 isoform 1 [Homo sapiens] 92 4e-18 gi|37622343 zinc finger protein 266 [Homo sapiens] 91 9e-18 gi|37622349 zinc finger protein 266 [Homo sapiens] 91 9e-18 gi|13376064 zinc finger protein 408 [Homo sapiens] 90 1e-17 >gi|154146199 sal-like 3 [Homo sapiens] Length = 1300 Score = 2630 bits (6818), Expect = 0.0 Identities = 1300/1300 (100%), Positives = 1300/1300 (100%) Query: 1 MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEF 60 MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEF Sbjct: 1 MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEF 60 Query: 61 FKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGA 120 FKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGA Sbjct: 61 FKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGA 120 Query: 121 EGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQ 180 EGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQ Sbjct: 121 EGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQ 180 Query: 181 FSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRP 240 FSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRP Sbjct: 181 FSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRP 240 Query: 241 SLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGAS 300 SLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGAS Sbjct: 241 SLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGAS 300 Query: 301 TPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPS 360 TPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPS Sbjct: 301 TPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPS 360 Query: 361 PLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKH 420 PLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKH Sbjct: 361 PLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKH 420 Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMN 480 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMN Sbjct: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMN 480 Query: 481 PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY 540 PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY Sbjct: 481 PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY 540 Query: 541 ADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVS 600 ADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVS Sbjct: 541 ADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVS 600 Query: 601 LPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSE 660 LPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSE Sbjct: 601 LPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSE 660 Query: 661 TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720 TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG Sbjct: 661 TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720 Query: 721 NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMD 780 NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMD Sbjct: 721 NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMD 780 Query: 781 SELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSI 840 SELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSI Sbjct: 781 SELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSI 840 Query: 841 AALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESS 900 AALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESS Sbjct: 841 AALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESS 900 Query: 901 SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960 SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA Sbjct: 901 SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960 Query: 961 PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020 PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL Sbjct: 961 PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020 Query: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL Sbjct: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080 Query: 1081 PAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKP 1140 PAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKP Sbjct: 1081 PAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKP 1140 Query: 1141 FGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDL 1200 FGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDL Sbjct: 1141 FGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDL 1200 Query: 1201 AARAMNVDPSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGSMASGM 1260 AARAMNVDPSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGSMASGM Sbjct: 1201 AARAMNVDPSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGSMASGM 1260 Query: 1261 DKARTGSSPPIVSLDKASSETAASRPFTRFIEDNKEIGIN 1300 DKARTGSSPPIVSLDKASSETAASRPFTRFIEDNKEIGIN Sbjct: 1261 DKARTGSSPPIVSLDKASSETAASRPFTRFIEDNKEIGIN 1300 >gi|118442837 sal-like 1 isoform a [Homo sapiens] Length = 1324 Score = 1224 bits (3168), Expect = 0.0 Identities = 706/1377 (51%), Positives = 886/1377 (64%), Gaps = 136/1377 (9%) Query: 1 MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESR-SGGEETSVCEKCCAE 59 MSRRKQAKPQH +SD PE A+ D + G SR + ++ VC +CCAE Sbjct: 1 MSRRKQAKPQHFQSD---------PEVASLPRRDGDTEKGQPSRPTKSKDAHVCGRCCAE 51 Query: 60 FFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSER------------- 106 FF+ +D L H+++CTK VLIV+E+ PA PPE F P +P E+ Sbjct: 52 FFELSDLLLHKKNCTKNQLVLIVNEN-PASPPETFSPSPPPDNPDEQMNDTVNKTDQVDC 110 Query: 107 ----------------AESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPA 150 E+ A ++G+ + G + + +G + + Sbjct: 111 SDLSEHNGLDREESMEVEAPVANKSGSGTSSGSHSSTAPSSSSSSSSSSGGGGSSSTGTS 170 Query: 151 APAPPTPAYGAPST---------NVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAA 201 A P G +T NV +E L STKVAVAQFSQ AR G SG A Sbjct: 171 AITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEARCGGASGG-----KLA 225 Query: 202 VPLILEQLMALQQQQIHQLQLIEQIRSQVALM--QRPPPRPSLSPAAAPSAPGPAP-SQL 258 VP ++EQL+ALQQQQIHQLQLIEQIR Q+ L+ Q S SP+ P S L Sbjct: 226 VPALMEQLLALQQQQIHQLQLIEQIRHQILLLASQNADLPTSSSPSQGTLRTSANPLSTL 285 Query: 259 PGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEP-SAPAAPSAA 317 + L+A A A S A+ + + P+ P+S + P+ S+P A Sbjct: 286 SSHLSQQLAAAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNTIIPSNSGSSPNMNILA 345 Query: 318 PAPAAPAPAPAPQSAASSQPQ----SASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIF 373 A P+ SA +S S+S+ PA A SLL A +PLLPQ +++ +F Sbjct: 346 AAVTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPAS---NPLLPQQASANSVF 402 Query: 374 PNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDS 433 P+PL +I TA L+ LSAL + RK KPPNV+ FE K+++++ FFKHKCRFCAKVFGSDS Sbjct: 403 PSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDS 462 Query: 434 ALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPT 493 ALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPE+LDN+PT Sbjct: 463 ALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDNIPT 522 Query: 494 CSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY--ADSPSATPASR 551 +GIPYGMS+PPEKPVT+WLD+KPVLPT+ TSVGL LPPT+P + + P+ P S Sbjct: 523 STGIPYGMSIPPEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKTEEPAPIPISH 582 Query: 552 SPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDA 611 S P PG +SG ES LGG P +AE +LP + ++ ++ Sbjct: 583 SATSP-----------PGSVKSDSG---GPESATRNLGGLP-EEAEGSTLPPSGGKSEES 627 Query: 612 PVGAQASAAPTSVD-------------GAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQT 658 G ++ PT+ G+ T+ +P LP +SEQFKA+FPFGGLLDS Q Sbjct: 628 --GMVTNSVPTASSSVLSSPAADCGPAGSATTFTNPLLPLMSEQFKAKFPFGGLLDSAQA 685 Query: 659 SETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTT 718 SETSKLQQLVENIDKK TDPN+C+ICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTT Sbjct: 686 SETSKLQQLVENIDKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTT 745 Query: 719 KGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDA 778 KGNLKTH+ VHRA PPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTP+P+ + ++ Sbjct: 746 KGNLKTHYSVHRAMPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDSYSES 805 Query: 779 MDSEL-AYDDKNAETLSSYDD----DMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSP 833 M+S+ ++D+KN + L ++ D D E S+ D + DA+ D S SP Sbjct: 806 MESDTGSFDEKNFDDLDNFSDENMEDCPEGSIPDTPKSADASQD----------SLSSSP 855 Query: 834 -PSVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAG 892 P +SSIAALENQMKMI++ ++ Q LKSVENGS E D L+NDSSS GD+ES+SAG Sbjct: 856 LPLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDMESQSAG 915 Query: 893 SPALSESSSS-QALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAP 951 SPA+SES+SS QALSP+ S E KSP + EE + + +E + + P +GGA Sbjct: 916 SPAISESTSSMQALSPSNSTQEF--HKSPSI---EEKPQRAVPSEFANGLSPTPVNGGAL 970 Query: 952 GRAG-----IKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFV 1006 I +E +LF R+RGK +T C +CGK FAC+SAL+IHYRSHTKERPF+ Sbjct: 971 DLTSSHAEKIIKEDSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFI 1030 Query: 1007 CALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVN 1066 C +C RG ST GNLKQH+LTH++++LPSQLF+P+ LGP+Q++ + +++ ++IK EVN Sbjct: 1031 CTVCNRGFSTKGNLKQHMLTHQMRDLPSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVN 1090 Query: 1067 G--HGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPP-PRRTPKQHNCQSCGKTFS 1123 G H + P VP+GP + +P+L P PRRTPKQH C +CGKTFS Sbjct: 1091 GFVHVSPQDSKDTPT----SHVPSGP--LSSSATSPVLLPALPRRTPKQHYCNTCGKTFS 1144 Query: 1124 SASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMA 1183 S+SALQIHERTHTGEKPF CTICGRAFTTKGNLKVHMGTHMWN+ PARRGRRLSV+ PM Sbjct: 1145 SSSALQIHERTHTGEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMT 1204 Query: 1184 LLGGDALKFSEMFQKDLAARAMNVDP-SFWNQYAAAITNGLAMKNNEISVIQNGGIPQLP 1242 LGG+ +KF EMFQKDLAAR+ + DP SFWNQYAAA++NGLAMK NEISVIQNGGIP +P Sbjct: 1205 FLGGNPVKFPEMFQKDLAARSGSGDPSSFWNQYAAALSNGLAMKANEISVIQNGGIPPIP 1264 Query: 1243 VSLGGSALPPLGSMASGMDKARTGS-SPPIVSLDK-ASSETAASRPFTRFIEDNKEI 1297 SLG P+ + +++ + + P+ L+K ASSE + FTRF+ED+KEI Sbjct: 1265 GSLGSGNSSPVSGLTGNLERLQNSEPNAPLAGLEKMASSENGTNFRFTRFVEDSKEI 1321 >gi|189217876 sal-like 1 isoform b [Homo sapiens] Length = 1227 Score = 1161 bits (3004), Expect = 0.0 Identities = 659/1244 (52%), Positives = 823/1244 (66%), Gaps = 96/1244 (7%) Query: 104 SERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPS 163 S E+ A ++G+ + G + + +G + +A P G + Sbjct: 27 SMEVEAPVANKSGSGTSSGSHSSTAPSSSSSSSSSSGGGGSSSTGTSAITTSLPQLGDLT 86 Query: 164 T---------NVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQ 214 T NV +E L STKVAVAQFSQ AR G SG AVP ++EQL+ALQQ Sbjct: 87 TLGNFSVINSNVIIENLQSTKVAVAQFSQEARCGGASGG-----KLAVPALMEQLLALQQ 141 Query: 215 QQIHQLQLIEQIRSQVALM--QRPPPRPSLSPAAAPSAPGPAP-SQLPGLAALPLSAGAP 271 QQIHQLQLIEQIR Q+ L+ Q S SP+ P S L + L+A A Sbjct: 142 QQIHQLQLIEQIRHQILLLASQNADLPTSSSPSQGTLRTSANPLSTLSSHLSQQLAAAAG 201 Query: 272 AAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEP-SAPAAPSAAPAPAAPAPAPAPQ 330 A S A+ + + P+ P+S + P+ S+P A A P+ Sbjct: 202 LAQSLASQSASISGVKQLPPIQLPQSSSGNTIIPSNSGSSPNMNILAAAVTTPSSEKVAS 261 Query: 331 SAASSQPQ----SASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANA 386 SA +S S+S+ PA A SLL A +PLLPQ +++ +FP+PL +I TA Sbjct: 262 SAGASHVSNPAVSSSSSPAFAISSLLSPAS---NPLLPQQASANSVFPSPLPNIGTTAED 318 Query: 387 LDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGER 446 L+ LSAL + RK KPPNV+ FE K+++++ FFKHKCRFCAKVFGSDSALQIHLRSHTGER Sbjct: 319 LNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQIHLRSHTGER 378 Query: 447 PFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPE 506 PFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPE+LDN+PT +GIPYGMS+PPE Sbjct: 379 PFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEHLDNIPTSTGIPYGMSIPPE 438 Query: 507 KPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY--ADSPSATPASRSPQRPSPASSECA 564 KPVT+WLD+KPVLPT+ TSVGL LPPT+P + + P+ P S S P Sbjct: 439 KPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLIPFIKTEEPAPIPISHSATSP-------- 490 Query: 565 SLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSV 624 PG +SG ES LGG P +AE +LP + ++ ++ G ++ PT+ Sbjct: 491 ---PGSVKSDSG---GPESATRNLGGLP-EEAEGSTLPPSGGKSEES--GMVTNSVPTAS 541 Query: 625 D-------------GAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENI 671 G+ T+ +P LP +SEQFKA+FPFGGLLDS Q SETSKLQQLVENI Sbjct: 542 SSVLSSPAADCGPAGSATTFTNPLLPLMSEQFKAKFPFGGLLDSAQASETSKLQQLVENI 601 Query: 672 DKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRA 731 DKK TDPN+C+ICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTH+ VHRA Sbjct: 602 DKKATDPNECIICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHYSVHRA 661 Query: 732 KPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSEL-AYDDKNA 790 PPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTP+P+ + ++M+S+ ++D+KN Sbjct: 662 MPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPVPDSYSESMESDTGSFDEKNF 721 Query: 791 ETLSSYDD----DMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSP-PSVISSIAALEN 845 + L ++ D D E S+ D + DA+ D S SP P +SSIAALEN Sbjct: 722 DDLDNFSDENMEDCPEGSIPDTPKSADASQD----------SLSSSPLPLEMSSIAALEN 771 Query: 846 QMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSS-QA 904 QMKMI++ ++ Q LKSVENGS E D L+NDSSS GD+ES+SAGSPA+SES+SS QA Sbjct: 772 QMKMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDMESQSAGSPAISESTSSMQA 831 Query: 905 LSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAG-----IKEE 959 LSP+ S E KSP + EE + + +E + + P +GGA I +E Sbjct: 832 LSPSNSTQEF--HKSPSI---EEKPQRAVPSEFANGLSPTPVNGGALDLTSSHAEKIIKE 886 Query: 960 APFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGN 1019 +LF R+RGK +T C +CGK FAC+SAL+IHYRSHTKERPF+C +C RG ST GN Sbjct: 887 DSLGILFPFRDRGKFKNTACDICGKTFACQSALDIHYRSHTKERPFICTVCNRGFSTKGN 946 Query: 1020 LKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNG--HGKAMALGEG 1077 LKQH+LTH++++LPSQLF+P+ LGP+Q++ + +++ ++IK EVNG H + Sbjct: 947 LKQHMLTHQMRDLPSQLFEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDT 1006 Query: 1078 PPLPAGVQVPAGPQTVMGPGLAPMLAPP-PRRTPKQHNCQSCGKTFSSASALQIHERTHT 1136 P VP+GP + +P+L P PRRTPKQH C +CGKTFSS+SALQIHERTHT Sbjct: 1007 PT----SHVPSGP--LSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIHERTHT 1060 Query: 1137 GEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMF 1196 GEKPF CTICGRAFTTKGNLKVHMGTHMWN+ PARRGRRLSV+ PM LGG+ +KF EMF Sbjct: 1061 GEKPFACTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDGPMTFLGGNPVKFPEMF 1120 Query: 1197 QKDLAARAMNVDP-SFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGS 1255 QKDLAAR+ + DP SFWNQYAAA++NGLAMK NEISVIQNGGIP +P SLG P+ Sbjct: 1121 QKDLAARSGSGDPSSFWNQYAAALSNGLAMKANEISVIQNGGIPPIPGSLGSGNSSPVSG 1180 Query: 1256 MASGMDKARTGS-SPPIVSLDK-ASSETAASRPFTRFIEDNKEI 1297 + +++ + + P+ L+K ASSE + FTRF+ED+KEI Sbjct: 1181 LTGNLERLQNSEPNAPLAGLEKMASSENGTNFRFTRFVEDSKEI 1224 >gi|10047144 sal-like 4 [Homo sapiens] Length = 1053 Score = 595 bits (1535), Expect = e-170 Identities = 428/1075 (39%), Positives = 540/1075 (50%), Gaps = 203/1075 (18%) Query: 1 MSRRKQAKPQHLKSDE---ELLPPDGAPEHA-----APGEGAEDA-------------DS 39 MSRRKQAKPQH+ S+E E P PE A AP G A D Sbjct: 1 MSRRKQAKPQHINSEEDQGEQQPQQQTPEFADAAPAAPAAGELGAPVNHPGNDEVASEDE 60 Query: 40 GPESRSGGEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSP 99 R EET VCEKCCAEFF ++FLEH+++CTK PPVLI+++ P EDF Sbjct: 61 ATVKRLRREETHVCEKCCAEFFSISEFLEHKKNCTKNPPVLIMNDSEGPVPSEDFSGAVL 120 Query: 100 ASSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTP-- 157 + P+ + E G + + +P + + E A PPTP Sbjct: 121 SHQPTSPGSKDCHRENGGSSEDMKEKPDAESVVYLKTETA-------------LPPTPQD 167 Query: 158 ----AYG-APSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMAL 212 A G +TNVTL+AL TKVAV Q S A A GA ++P +LEQ++ L Sbjct: 168 ISYLAKGKVANTNVTLQALRGTKVAVNQRSADALPAPVPGAN------SIPWVLEQILCL 221 Query: 213 QQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPA 272 QQQQ+ Q+QL EQIR QV + S + A G SQ A LS A Sbjct: 222 QQQQLQQIQLTEQIRIQVNMWASHALHSSGAGADTLKTLGSHMSQQVSAAVALLSQKA-- 279 Query: 273 AAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSA 332 G+Q LS A A P A P + Sbjct: 280 ---------------GSQGLSLD-----------------ALKQAKLPHANIP------S 301 Query: 333 ASSQPQSASTPPALAPGS---LLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDP 389 A+S P L P L LPS LLPQ S V+F +P ++A + Sbjct: 302 ATSSLSPGLAPFTLKPDGTRVLPNVMSRLPSALLPQAPGS-VLFQSPFSTVALDTS---- 356 Query: 390 LSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFK 449 K KGKPPN+S + K E +KHKC++C+KVFG+DS+LQIHLRSHTGERPF Sbjct: 357 -----KKGKGKPPNISAVDVKPKDEAALYKHKCKYCSKVFGTDSSLQIHLRSHTGERPFV 411 Query: 450 CNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLP-PEKP 508 C++CG+RF+TKGNLKVHF RH P ++ NP E+ D V +GIPY +S+P P Sbjct: 412 CSVCGHRFTTKGNLKVHFHRH----PQVKANPQLFAEFQDKVAAGNGIPYALSVPDPIDE 467 Query: 509 VTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSP 568 + LDSKPVL V TSVGL PQ +LS Sbjct: 468 PSLSLDSKPVL--VTTSVGL------------------------PQ----------NLSS 491 Query: 569 GLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAP 628 G N P+ L GG SLP GD G +P Sbjct: 492 GTN------------PKDLTGG---------SLP------GDLQPGP-----------SP 513 Query: 629 TSLGSPGLPAVSEQFKAQFPFGGLLDSMQT----SETSKLQQLVENIDKKMTDPNQCVIC 684 S G P LP V + + P G T SET KLQQLVENIDK TDPN+C+IC Sbjct: 514 ESEGGPTLPGVGPNYNS--PRAGGFQGSGTPEPGSETLKLQQLVENIDKATTDPNECLIC 571 Query: 685 HRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPIC 744 HRVLSCQS+LKMHYRTHTGERPF+CKICGRAF+TKGNLKTH GVHR ++ QHSCPIC Sbjct: 572 HRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNTSIKTQHSCPIC 631 Query: 745 QKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSELAYDDKNAETLSSYDDDMDENS 804 QKKFTNAV+LQQHIRMHMGGQIPNTPLPE D SE +N T + DD+ E+ Sbjct: 632 QKKFTNAVMLQQHIRMHMGGQIPNTPLPENPCDFTGSEPMTVGENGSTGAICHDDVIESI 691 Query: 805 MEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGLKS 864 ++ ++A + +K SP + +A+L+ K+ + + Q+ S Sbjct: 692 DVEEVSSQEAPSSSSKVPTPLPSIHSASPTLGFAMMASLDAPGKVGPAPFNLQR---QGS 748 Query: 865 VENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSPGLGA 924 ENGS ESD L+NDSSS +GD E +S SP + E++S QALSPA S ES +SKSP G+ Sbjct: 749 RENGSVESDGLTNDSSSLMGDQEYQSR-SPDILETTSFQALSPANSQAESIKSKSPDAGS 807 Query: 925 PEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAP------------FSLLFLSRERG 972 E E +TE + ++ P + +K E P + L ++ R Sbjct: 808 KAESSE-NSRTEM-EGRSSLPSTFIRAPPTYVKVEVPGTFVGPSTLSPGMTPLLAAQPRR 865 Query: 973 KCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 + C CGK F+ SAL+IH R+HT E+PFVC +C R +T GNLK H +TH Sbjct: 866 QAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNLKVHYMTH 920 Score = 233 bits (595), Expect = 7e-61 Identities = 130/267 (48%), Positives = 167/267 (62%), Gaps = 17/267 (6%) Query: 1042 ALGPSQSTPSLISSAAPTM-IKMEVNGHGKAMALGEG---------PPLPAGVQVPA--- 1088 AL P+ S I S +P K E + + + G PP V+VP Sbjct: 787 ALSPANSQAESIKSKSPDAGSKAESSENSRTEMEGRSSLPSTFIRAPPTYVKVEVPGTFV 846 Query: 1089 GPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGR 1148 GP T + PG+ P+LA PRR KQH C CGK FSSASALQIHERTHTGEKPF C ICGR Sbjct: 847 GPST-LSPGMTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGR 905 Query: 1149 AFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQKDLAARAMNVD 1208 AFTTKGNLKVH TH NN ARRGR+L++EN MALLG D + SE+F K++ A ++NVD Sbjct: 906 AFTTKGNLKVHYMTHGANNNSARRGRKLAIENTMALLGTDGKRVSEIFPKEILAPSVNVD 965 Query: 1209 PSFWNQYAAAITNGLAMKNNEISVIQNGGIPQLPVSLGGSALPPLGSMASGMDKARTGSS 1268 P WNQY + + GLA+K NEISVIQ+GG+P LPVSLG +++ + S MD +++G S Sbjct: 966 PVVWNQYTSMLNGGLAVKTNEISVIQSGGVPTLPVSLGATSVVN-NATVSKMDGSQSGIS 1024 Query: 1269 PPIVSLDKASSETAASRPFTRFIEDNK 1295 + ++++ F F+E+NK Sbjct: 1025 ADVEK--PSATDGVPKHQFPHFLEENK 1049 Score = 131 bits (330), Expect = 4e-30 Identities = 114/368 (30%), Positives = 157/368 (42%), Gaps = 84/368 (22%) Query: 875 LSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSPGLGA----PEEPQE 930 +S S+AV L S+ AGS LS + QA P + + S SPGL P+ + Sbjct: 264 MSQQVSAAVA-LLSQKAGSQGLSLDALKQAKLPHANIPSATSSLSPGLAPFTLKPDGTRV 322 Query: 931 IPLKTERPDSPAA--APGSGGAPGRAGIKEEAPFSLLFLS---RERGKCPSTV------- 978 +P R S APGS + ++PFS + L + +GK P+ Sbjct: 323 LPNVMSRLPSALLPQAPGS--------VLFQSPFSTVALDTSKKGKGKPPNISAVDVKPK 374 Query: 979 ---------CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRL 1029 C C K F S+L+IH RSHT ERPFVC++C +T GNLK H H Sbjct: 375 DEAALYKHKCKYCSKVFGTDSSLQIHLRSHTGERPFVCSVCGHRFTTKGNLKVHFHRHPQ 434 Query: 1030 KELPSQLFDP-----------NFALGPSQ--STPSLISSAAPTMIKMEVNGHGKAMALGE 1076 + QLF +AL PSL + P ++ V G + ++ G Sbjct: 435 VKANPQLFAEFQDKVAAGNGIPYALSVPDPIDEPSLSLDSKPVLVTTSV-GLPQNLSSGT 493 Query: 1077 GP------PLPAGVQVPAGPQTVMG---PGLAPMLAPP---------------------- 1105 P LP +Q P++ G PG+ P P Sbjct: 494 NPKDLTGGSLPGDLQPGPSPESEGGPTLPGVGPNYNSPRAGGFQGSGTPEPGSETLKLQQ 553 Query: 1106 -----PRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHM 1160 + T + C C + S S+L++H RTHTGE+PF C ICGRAF+TKGNLK H+ Sbjct: 554 LVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHL 613 Query: 1161 GTHMWNNA 1168 G H N + Sbjct: 614 GVHRTNTS 621 Score = 125 bits (314), Expect = 3e-28 Identities = 136/489 (27%), Positives = 198/489 (40%), Gaps = 85/489 (17%) Query: 312 AAPSAAP-APAAPAPAPAPQSAASSQP-------------QSASTPPALAPGSLLGAAPG 357 AA + P A + P P P + S+P S + P L GSL G Sbjct: 450 AAGNGIPYALSVPDPIDEPSLSLDSKPVLVTTSVGLPQNLSSGTNPKDLTGGSLPGDLQP 509 Query: 358 LPSPLL---PQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAE 414 PSP P G + +P + +P S +K ++ V + Sbjct: 510 GPSPESEGGPTLPGVGPNYNSPRAGGFQGSGTPEPGSETLKLQQ------LVENIDKATT 563 Query: 415 DPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK- 473 DP ++C C +V S+L++H R+HTGERPF+C ICG FSTKGNLK H H+ Sbjct: 564 DP---NECLICHRVLSCQSSLKMHYRTHTGERPFQCKICGRAFSTKGNLKTHLGVHRTNT 620 Query: 474 ---------------------YPHIQMNP------YPVPE----YLDNVPTCSGIPYGMS 502 HI+M+ P+PE + + P G Sbjct: 621 SIKTQHSCPICQKKFTNAVMLQQHIRMHMGGQIPNTPLPENPCDFTGSEPMTVGENGSTG 680 Query: 503 LPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAH------GYA-----DSPSAT-PAS 550 V +D + V S ++P +P H G+A D+P PA Sbjct: 681 AICHDDVIESIDVEEVSSQEAPSSSSKVPTPLPSIHSASPTLGFAMMASLDAPGKVGPAP 740 Query: 551 RSPQRPSPASSECASL-SPGLNHVESGVSATAE----SPQSLLGGPPLTKAEPVSLPCTN 605 + QR S E S+ S GL + S + E SP +L P + + Sbjct: 741 FNLQRQG--SRENGSVESDGLTNDSSSLMGDQEYQSRSPD-ILETTSFQALSPANSQAES 797 Query: 606 ARAGDAPVGAQASAAP---TSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETS 662 ++ G++A ++ T ++G +SL S + A K + P G T Sbjct: 798 IKSKSPDAGSKAESSENSRTEMEGR-SSLPSTFIRAPPTYVKVEVP--GTFVGPSTLSPG 854 Query: 663 KLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNL 722 + L+ ++ + C C + S SAL++H RTHTGE+PF C ICGRAFTTKGNL Sbjct: 855 -MTPLLAAQPRRQAKQHGCTRCGKNFSSASALQIHERTHTGEKPFVCNICGRAFTTKGNL 913 Query: 723 KTHFGVHRA 731 K H+ H A Sbjct: 914 KVHYMTHGA 922 Score = 65.9 bits (159), Expect = 2e-10 Identities = 100/453 (22%), Positives = 149/453 (32%), Gaps = 129/453 (28%) Query: 708 KCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIP 767 KCK C + F T +L+ H H + P C +C +FT L+ H H + Sbjct: 383 KCKYCSKVFGTDSSLQIHLRSHTGERPF----VCSVCGHRFTTKGNLKVHFHRHPQVKA- 437 Query: 768 NTPLPEGFQDAMDSELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAG 827 N L FQD + + S D +DE S+ D+ KP+L Sbjct: 438 NPQLFAEFQDKVAA-----GNGIPYALSVPDPIDEPSLSLDS----------KPVL---- 478 Query: 828 SCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLE 887 V +S+ +N + S + + LTG S GDL+ Sbjct: 479 --------VTTSVGLPQN----LSSGTNPKDLTG------------------GSLPGDLQ 508 Query: 888 SRSAGSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGS 947 P PS PG+G +SP A Sbjct: 509 -------------------PGPSPESEGGPTLPGVGP------------NYNSPRAGGFQ 537 Query: 948 GGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVC 1007 G G E L + ++ C +C + +C+S+L++HYR+HT ERPF C Sbjct: 538 GSGTPEPG-SETLKLQQLVENIDKATTDPNECLICHRVLSCQSSLKMHYRTHTGERPFQC 596 Query: 1008 ALCRRGCSTMGNLK--------------------------------QHLLTHRLKELPSQ 1035 +C R ST GNLK QH+ H ++P+ Sbjct: 597 KICGRAFSTKGNLKTHLGVHRTNTSIKTQHSCPICQKKFTNAVMLQQHIRMHMGGQIPNT 656 Query: 1036 LFDPN---------FALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQV 1086 N +G + ST ++ I +E +A + P P Sbjct: 657 PLPENPCDFTGSEPMTVGENGSTGAICHDDVIESIDVEEVSSQEAPSSSSKVPTPLPSIH 716 Query: 1087 PAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCG 1119 A P +G + L P + P N Q G Sbjct: 717 SASP--TLGFAMMASLDAPGKVGPAPFNLQRQG 747 Score = 30.8 bits (68), Expect = 8.8 Identities = 13/26 (50%), Positives = 16/26 (61%) Query: 1112 QHNCQSCGKTFSSASALQIHERTHTG 1137 QH+C C K F++A LQ H R H G Sbjct: 625 QHSCPICQKKFTNAVMLQQHIRMHMG 650 >gi|49087132 sal-like 2 [Homo sapiens] Length = 1007 Score = 470 bits (1210), Expect = e-132 Identities = 378/1165 (32%), Positives = 507/1165 (43%), Gaps = 280/1165 (24%) Query: 1 MSRRKQAKPQHLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEF 60 MSRRKQ KPQ L SD E P + G+ +E+ + VC KCCA+F Sbjct: 1 MSRRKQRKPQQLISDCE------GPSASENGDASEE-----------DHPQVCAKCCAQF 43 Query: 61 FKWADFLEHQRSCTKLPPVLIV---------HEDAPAPPPEDFPEP----SPASSPSERA 107 +FL HQ +C+ PPV+++ + P PE P + S+P + Sbjct: 44 TDPTEFLAHQNACSTDPPVMVIIGGQENPNNSSASSEPRPEGHNNPQVMDTEHSNPPDSG 103 Query: 108 ESEAAEEAGAEGAEGEARP-----------------VEKEAEPMDAEPAGDTRAPRPPPA 150 S + GE P + + + A P P PPP Sbjct: 104 SSVPTDPTWGPERRGEESPGHFLVAATGTAAGGGGGLILASPKLGATPLPPESTPAPPPP 163 Query: 151 APAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLM 210 P PP P G+ N+ PLILE+L Sbjct: 164 PPPPPPPGVGSGHLNI------------------------------------PLILEELR 187 Query: 211 ALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGA 270 LQQ+QIHQ+Q+ EQI QV L+ S AP +PS+LPG +A + Sbjct: 188 VLQQRQIHQMQMTEQICRQVLLLG--------SLGQTVGAPA-SPSELPGTG----TASS 234 Query: 271 PAAAIAGSGPAAPA----AFEGAQPLSRPESGASTPGG-------PAEPSAPAAPSAAPA 319 + P P + S SGA TP P P + Sbjct: 235 TKPLLPLFSPIKPVQTSKTLASSSSSSSSSSGAETPKQAFFHLYHPLGSQHPFSAGGVGR 294 Query: 320 PAAPAPAPAPQSAASSQPQSAS------TPPALAPGSLLGAAPGLPSPLLPQTSASGVIF 373 P PAP+P S+ AS + L LGAA GL + T++ G++ Sbjct: 295 SHKPTPAPSPALPGSTDQLIASPHLAFPSTTGLLAAQCLGAARGLEA-----TASPGLLK 349 Query: 374 PNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDS 433 P K +S E E P +HKCRFCAKVFGSDS Sbjct: 350 P-----------------------KNGSGELSYGEVMGPLEKPGGRHKCRFCAKVFGSDS 386 Query: 434 ALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPT 493 ALQIHLRSHTGERP+KCN+CGNRF+T+GNLKVHF RH+EKYPH+QMNP+PVPE+LD V T Sbjct: 387 ALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRHREKYPHVQMNPHPVPEHLDYVIT 446 Query: 494 CSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSP 553 SG+PYGMS+PPEK A+ +ATP Sbjct: 447 SSGLPYGMSVPPEK---------------------------------AEEEAATPGGGVE 473 Query: 554 QRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTK------AEPVSLPCTNA- 606 ++P AS+ S + L + + + TA +P G P K EP + N Sbjct: 474 RKPLVASTTALSATESLTLLSTS-AGTATAP----GLPAFNKFVLMKAVEPKNKADENTP 528 Query: 607 --RAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKA--QFPFGGLLDSM--QTSE 660 G A G S+ T + + P ++ FK+ FPF +L+ + SE Sbjct: 529 PGSEGSAISGVAESSTATRMQLSKLVTSLPSWALLTNHFKSTGSFPFPYVLEPLGASPSE 588 Query: 661 TSKLQQLVENIDKK------------------------MTDPNQCVICHRVLSCQSALKM 696 TSKLQQLVE ID++ + PNQCVIC RVLSC AL++ Sbjct: 589 TSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQCVICLRVLSCPRALRL 648 Query: 697 HYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQ 756 HY H GERPFKCK+CGRAF+T+GNL+ HF H+A P R Q+SCPICQKKFTNAV LQQ Sbjct: 649 HYGQHGGERPFKCKVCGRAFSTRGNLRAHFVGHKASPAARAQNSCPICQKKFTNAVTLQQ 708 Query: 757 HIRMHMGGQIPN--TPLPEG---------FQDAMDSELAYDDKNAETLSSYDDDMDENSM 805 H+RMH+GGQIPN T LPEG Q + ++ + ++ S ++ +E Sbjct: 709 HVRMHLGGQIPNGGTALPEGGGAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEE 768 Query: 806 EDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGLKSV 865 ED+ E +D + S AG S S+ DS Sbjct: 769 EDEEEEEDVTDED-----SLAGRGSESGGEKAISVRG--------DS------------- 802 Query: 866 ENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSP----- 920 E SG + + +++A E S +E ++ Q+ P P +S P Sbjct: 803 EEASGAEEEVGTVAAAATAGKEMDS------NEKTTQQSSLPPPPPPDSLDQPQPMEQGS 856 Query: 921 --GLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPS-T 977 LG EE K ER SPA+A G + EE + +E G+ S Sbjct: 857 SGVLGGKEEGG----KPERSSSPASALTPEGEATSVTLVEELSLQEA-MRKEPGESSSRK 911 Query: 978 VCGVCGKPFACKSALEIHYRSHTKERP-FVCALCRRGCSTMGNLKQHLLTHRLKELPSQL 1036 C VCG+ F ++ALE H ++H KE P F C CR+G LK+H+L L Q Sbjct: 912 ACEVCGQAFPSQAALEEHQKTHPKEGPLFTCVFCRQGFLERATLKKHML---LAHHQVQP 968 Query: 1037 FDPNFALGPSQ-STPSLISSAAPTM 1060 F P+ GP + SL+ +P++ Sbjct: 969 FAPH---GPQNIAALSLVPGCSPSI 990 Score = 77.0 bits (188), Expect = 1e-13 Identities = 32/59 (54%), Positives = 40/59 (67%) Query: 1105 PPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 P + +H C+ C K F S SALQIH R+HTGE+P+ C +CG FTT+GNLKVH H Sbjct: 365 PLEKPGGRHKCRFCAKVFGSDSALQIHLRSHTGERPYKCNVCGNRFTTRGNLKVHFHRH 423 Score = 62.4 bits (150), Expect = 3e-09 Identities = 45/151 (29%), Positives = 65/151 (43%), Gaps = 22/151 (14%) Query: 1024 LLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAG 1083 LLT+ K S F + L P ++PS S + K++ G + G P Sbjct: 562 LLTNHFKSTGSFPFP--YVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAP---- 615 Query: 1084 VQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGC 1143 T P AP + + C C + S AL++H H GE+PF C Sbjct: 616 --------TTSAP------APSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKC 661 Query: 1144 TICGRAFTTKGNLKVHMGTHMWNNAPARRGR 1174 +CGRAF+T+GNL+ H H +PA R + Sbjct: 662 KVCGRAFSTRGNLRAHFVGH--KASPAARAQ 690 Score = 49.7 bits (117), Expect = 2e-05 Identities = 28/85 (32%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Query: 1081 PAGVQVPAGPQT----VMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHT 1136 PA P G T V L + P + + C+ CG+ F S +AL+ H++TH Sbjct: 875 PASALTPEGEATSVTLVEELSLQEAMRKEPGESSSRKACEVCGQAFPSQAALEEHQKTHP 934 Query: 1137 GEKP-FGCTICGRAFTTKGNLKVHM 1160 E P F C C + F + LK HM Sbjct: 935 KEGPLFTCVFCRQGFLERATLKKHM 959 Score = 34.3 bits (77), Expect = 0.80 Identities = 67/280 (23%), Positives = 112/280 (40%), Gaps = 38/280 (13%) Query: 873 DRLSNDSSSAVGDLESRS--AGSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQE 930 ++ ++++ G +E + A + ALS + S LS + + +PGL P + Sbjct: 459 EKAEEEAATPGGGVERKPLVASTTALSATESLTLLSTSAGT-----ATAPGL--PAFNKF 511 Query: 931 IPLKTERPDSPA---AAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFA 987 + +K P + A PGS G+ +G+ E + + + LS+ PS Sbjct: 512 VLMKAVEPKNKADENTPPGSEGS-AISGVAESSTATRMQLSKLVTSLPSW---------- 560 Query: 988 CKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQ 1047 + L H++S T PF L G S K L ++ + + P+ Sbjct: 561 --ALLTNHFKS-TGSFPFPYVLEPLGASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTT 617 Query: 1048 STPSLISSAAP----TMIKMEVNGHGKAMALG---EGPPLPAGVQVPAGPQTVMGPGLAP 1100 S P+ SSA+ +I + V +A+ L G P +V + G A Sbjct: 618 SAPAPSSSASSGPNQCVICLRVLSCPRALRLHYGQHGGERPFKCKVCGRAFSTRGNLRAH 677 Query: 1101 ML---APPPRRTPKQHNCQSCGKTFSSASALQIHERTHTG 1137 + A P R Q++C C K F++A LQ H R H G Sbjct: 678 FVGHKASPAARA--QNSCPICQKKFTNAVTLQQHVRMHLG 715 >gi|138175817 zinc finger protein 236 [Homo sapiens] Length = 1845 Score = 131 bits (330), Expect = 4e-30 Identities = 136/535 (25%), Positives = 213/535 (39%), Gaps = 78/535 (14%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740 C C + S L H R HTGERPFKC CG+AF KG L+TH H + P H+ Sbjct: 199 CPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKP----HA 254 Query: 741 CPICQKKFTNAVVLQQHI-RMHMGGQIPNTPLPEGFQDAMDSELAYDDKNAETLSSYDDD 799 C C F+ LQ H+ R+H ++ N P +E + K+ +L+++ Sbjct: 255 CAFCPAAFSQKGNLQSHVQRVH--SEVKNGPTYN------CTECSCVFKSLGSLNTHISK 306 Query: 800 MDENSMEDDAELKDAATDPAKPLLSYAGSCPP--SPPSVISSIAALENQMKMIDSVMSCQ 857 M ++ ++T+ A L + P + +S ++ + + D + Sbjct: 307 MHMGGPQNST----SSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLL 362 Query: 858 QLTGLKSVENGSGESDRLSNDSSSAVG---DLESRSAGSPALSE-------SSSSQALSP 907 +L+ VE SG+S + S VG D+ ++ + LS + S A + Sbjct: 363 ELSEPAPVE--SGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKTS 420 Query: 908 APSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFL 967 AP +++P + + Q P E+ + +P + IK+++PF L Sbjct: 421 AP------HAQNPDVSSVSNEQTDPTDAEQ-EKEQESPEKLDKKEKKMIKKKSPF-LPGS 472 Query: 968 SRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 RE VC C K F S L H R HT E+PF C C R + L H+ TH Sbjct: 473 IREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTH 532 Query: 1028 R-LKELPSQLFDPNFALGPSQSTPSLISSAAPTMI------KMEVNGHGKA--------- 1071 +K Q +F+ S + + K +GH K Sbjct: 533 TGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHT 592 Query: 1072 -MALGEGPPLPAGVQV-----PAGPQTVMGPGLAP---MLAPPPR--------------R 1108 + PA V+V P + P L ++ P P+ Sbjct: 593 ELRKMRHQRKPAKVRVGKTNIPVPDIPLQEPILITDLGLIQPIPKNQFFQSYFNNNFVNE 652 Query: 1109 TPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 + + C C + + + L+ H R+HTGEKPF C+ CGR F + G LK H+ TH Sbjct: 653 ADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTH 707 Score = 119 bits (298), Expect = 2e-26 Identities = 141/552 (25%), Positives = 209/552 (37%), Gaps = 84/552 (15%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C R LK H RTHTG + FKC IC AFTT G+L+ H G+H P Sbjct: 684 PFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRP--- 740 Query: 738 QHSCPICQKKF-----------TNAVVLQQHIRMHM-GGQIPNTPLPEGFQDA---MDSE 782 + CP CQK F T+ L Q ++ H I ++ + + A M E Sbjct: 741 -YMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQQAASIDDSTVDQQSMQASTQMQVE 799 Query: 783 LAYDD--KNAETLSSYDDDMDENSME-----DDAELKDAATDPAKPL-LSYAGSCPPSPP 834 + D+ + AE +++ + M + + ++A L D +PL G P P Sbjct: 800 IESDELPQTAEVVAANPEAMLDLEPQHVVGTEEAGLGQQLAD--QPLEADEDGFVAPQDP 857 Query: 835 SVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSNDSS-SAVGDLESRSA-G 892 L + + QQ + G +D V L+ S Sbjct: 858 --------LRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLE 909 Query: 893 SPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPG 952 S ALS S Q+L APS+ + + L +E+ L+ + Sbjct: 910 SQALSTSFHQQSLLQAPSSDGM--NVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSY 967 Query: 953 RA-----GIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVC 1007 R G K+ + S G+ P C +CG+ F L+ H ++HT + F C Sbjct: 968 RCDYCNKGFKKSSHLKQHVRSHT-GEKPYK-CKLCGRGFVSSGVLKSHEKTHTGVKAFSC 1025 Query: 1008 ALCRRGCSTMGNLKQHLLTHR-LKELPSQLFDPNFA--------LGPSQSTPSLISSAAP 1058 ++C +T G+L +H+ TH +K + F + Q+ PS +S+ Sbjct: 1026 SVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQTVPSAVSATGE 1085 Query: 1059 T----MIKMEVNGHGKAMALGEGPP----------LPAGVQVPAGPQTVMGPGLAPMLAP 1104 T + E H A + P P TV L A Sbjct: 1086 TEGGDICMEEEEEHSDRNASRKSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAE 1145 Query: 1105 PPRRT------------PKQHNCQS-CGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151 R + PK NC + C K+F S L H R HTGEKP+ C CG++FT Sbjct: 1146 KDRISELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFT 1205 Query: 1152 TKGNLKVHMGTH 1163 K L H+ TH Sbjct: 1206 VKSTLDCHVKTH 1217 Score = 102 bits (255), Expect = 2e-21 Identities = 105/394 (26%), Positives = 144/394 (36%), Gaps = 74/394 (18%) Query: 418 FKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH- 476 F + C C K F S L H+R HTGERPFKC+ CG F+ KG L+ H +H + PH Sbjct: 195 FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQTHMIKHTGEKPHA 254 Query: 477 -------------IQMNPYPVPEYLDNVPT-----CSGIPYGMSLPPEKPVTTWLDSKPV 518 +Q + V + N PT CS + S Sbjct: 255 CAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCV---------------FKSLGS 299 Query: 519 LPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHV----- 573 L T + + + P + A +AT P + + A + AS P V Sbjct: 300 LNTHISKMHMGGPQNSTSSTETAHVLTATLFQTLPLQQTEAQATSASSQPSSQAVSDVIQ 359 Query: 574 ---ESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGA-QASAAPTSVDGAPT 629 E A ES QS G L+ ++ ++ + + A+A P A T Sbjct: 360 QLLELSEPAPVESGQSPQPGQQLSITVGINQDILQQALENSGLSSIPAAAHPNDSCHAKT 419 Query: 630 SLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKK--------------- 674 S P VS Q +E K Q+ E +DKK Sbjct: 420 SAPHAQNPDVSSVSNEQ-------TDPTDAEQEKEQESPEKLDKKEKKMIKKKSPFLPGS 472 Query: 675 MTDPN-----QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729 + + N C C + S L H R HT E+PFKC C RAF K L H H Sbjct: 473 IREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCPQCFRAFAVKSTLTAHIKTH 532 Query: 730 RAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + L+ HIR+H G Sbjct: 533 TGIKAFK----CQYCMKSFSTSGSLKVHIRLHTG 562 Score = 88.2 bits (217), Expect = 5e-17 Identities = 96/384 (25%), Positives = 146/384 (38%), Gaps = 49/384 (12%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + E PF KC C K F ALQ H+ HTGE+P C C FS KG + Q H Sbjct: 220 TGERPF---KCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAFSQKG----NLQSHV 272 Query: 472 EKYPHIQMNPYPVPEYLDNVPTCSGIPYG--------MSLPPEKPVTTWLDSKPVLPTVP 523 ++ N P Y +C G M + + T+ ++ VL T Sbjct: 273 QRVHSEVKNG---PTYNCTECSCVFKSLGSLNTHISKMHMGGPQNSTSSTETAHVL-TAT 328 Query: 524 TSVGLQLPPTVPGAHGYADSPSATPASRSPQR-------------PSPASSECASLSPGL 570 L L T A + PS+ S Q+ SP + S++ G+ Sbjct: 329 LFQTLPLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGI 388 Query: 571 NH-------VESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDA--PVGAQASA-- 619 N SG+S+ + T A P ++ + + P A+ Sbjct: 389 NQDILQQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQ 448 Query: 620 -APTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTD- 677 +P +D + P + + + + E K LV +I + Sbjct: 449 ESPEKLDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEK 508 Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C R + +S L H +THTG + FKC+ C ++F+T G+LK H +H P Sbjct: 509 PFKCPQCFRAFAVKSTLTAHIKTHTGIKAFKCQYCMKSFSTSGSLKVHIRLHTGVRPF-- 566 Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761 +CP C KKF + + HI H Sbjct: 567 --ACPHCDKKFRTSGHRKTHIASH 588 Score = 88.2 bits (217), Expect = 5e-17 Identities = 127/553 (22%), Positives = 203/553 (36%), Gaps = 105/553 (18%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + +S L H +THTG++ F C +C AF+TKG+LK H +H P + Sbjct: 1194 PYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFK- 1252 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLP------EGFQDAMDSELAYDDKNAE 791 CP C+ +F + + H++ H P EG Q + D N Sbjct: 1253 ---CPHCELRFRTSGRRKTHMQFHYKPDPKKARKPMTRSSSEGLQPVNLLNSSSTDPNVF 1309 Query: 792 TL--SSYDDDMDEN--------------SMEDDAELKDAATDPAKPLLS----YAGSCPP 831 + S D+N S+ +L + TD + L + Sbjct: 1310 IMNNSVLTGQFDQNLLQPGLVGQAILPASVSAGGDLTVSLTDGSLATLEGIQLQLAANLV 1369 Query: 832 SPPSVISSI--AALENQMKMID-SVMS---------CQQLTGLKSV--ENGSGESDRLSN 877 P IS I A++ N ID S++ QQLTG + +N S ++ + Sbjct: 1370 GPNVQISGIDAASINNITLQIDPSILQQTLQQGNLLAQQLTGEPGLAPQNSSLQTSDSTV 1429 Query: 878 DSSSAVGDLESRSAGSPA---------LSESSSSQALSPAPSNGESFRSKSPGLGAPE-E 927 +S + + S LSE S + + + + S GL +P Sbjct: 1430 PASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTNSSGTQDLTQVMTSQGLVSPSGG 1489 Query: 928 PQEIPLKTERPD-SPAAAPGSG-GAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKP 985 P EI L S A +G A +G +E ++ L+ G PST P Sbjct: 1490 PHEITLTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTT------P 1543 Query: 986 FACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHL------LTHRLKELPSQLFDP 1039 + + + + ++ T G L L +T + ++ P+ L DP Sbjct: 1544 MSPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDP 1603 Query: 1040 NFALGPSQSTPSLI--------SSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQ 1091 + + +P +I +SAA I +V G +A G P Sbjct: 1604 SLSGQGGAGSPQVILVSHTPQSASAACEEIAYQVAGVSGNLAPGNQP------------- 1650 Query: 1092 TVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHER-THTGEKPFGCTICGRAF 1150 + + H C C + FSSA+ L H + H E+ GC +C +AF Sbjct: 1651 ---------------EKEGRAHQCLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAF 1695 Query: 1151 TTKGNLKVHMGTH 1163 +LK HM TH Sbjct: 1696 KRATHLKEHMQTH 1708 Score = 79.7 bits (195), Expect = 2e-14 Identities = 88/378 (23%), Positives = 137/378 (36%), Gaps = 52/378 (13%) Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMN 480 KC C F + +L+ H+ H RP+ C C F T N K H++ + Sbjct: 714 KCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKTFKTSLNCK----------KHMKTH 763 Query: 481 PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGY 540 Y + + L + I + +D + + + V ++ A Sbjct: 764 RYELAQQLQQHQQAASID-----------DSTVDQQSMQASTQMQVEIESDELPQTAEVV 812 Query: 541 ADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAE---SPQSLLGG------- 590 A +P A PQ +E A L L + + A + +PQ L G Sbjct: 813 AANPEAM-LDLEPQHV--VGTEEAGLGQQL--ADQPLEADEDGFVAPQDPLRGHVDQFEE 867 Query: 591 --PPLTKAEPVSLP-------CTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSE 641 P EP LP + + PV ++ TS L Sbjct: 868 QSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPS 927 Query: 642 QFKAQFPFGGLLDSMQTSETSKLQ--QLVENIDKKMTDPNQCVICHRVLSCQSALKMHYR 699 + +S Q + Q Q +E+ + + +C C++ S LK H R Sbjct: 928 SDGMNVTTRLIQESSQEELDLQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVR 987 Query: 700 THTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIR 759 +HTGE+P+KCK+CGR F + G LK+H H SC +C FT L +H+ Sbjct: 988 SHTGEKPYKCKLCGRGFVSSGVLKSHEKTHTGVKAF----SCSVCNASFTTNGSLTRHMA 1043 Query: 760 MHMGGQIPNTPL-PEGFQ 776 HM + P EGF+ Sbjct: 1044 THMSMKPYKCPFCEEGFR 1061 Score = 73.6 bits (179), Expect = 1e-12 Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 46/190 (24%) Query: 978 VCGVCGKPFACKSALEIHYRSHTKE----RPFVCALCRRGCSTMGNLKQHLLTH-RLKEL 1032 +C CG F +S L +H H +E R C C++ T LK+H+ TH +++ Sbjct: 122 ICSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYKIRVS 181 Query: 1033 PSQLFDPNF-ALGPSQSTPSLISS-AAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGP 1090 ++ ++ N G + S P + P+ + + H GE P Sbjct: 182 STRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIH-----TGERP------------ 224 Query: 1091 QTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAF 1150 C CGK F+ ALQ H HTGEKP C C AF Sbjct: 225 ----------------------FKCSECGKAFNQKGALQTHMIKHTGEKPHACAFCPAAF 262 Query: 1151 TTKGNLKVHM 1160 + KGNL+ H+ Sbjct: 263 SQKGNLQSHV 272 Score = 72.0 bits (175), Expect = 3e-12 Identities = 52/185 (28%), Positives = 73/185 (39%), Gaps = 32/185 (17%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C VC K F+ ++L+ H H KE +C+ C + L H+ HR +EL Sbjct: 95 CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHR-QELAGTRQH 153 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 A T S + T K+ V+ + + + G Sbjct: 154 ACKACKKEFETSSELKEHMKTHYKIRVSS------------------TRSYNRNIDRSGF 195 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 ++C CGKTF S L H R HTGE+PF C+ CG+AF KG L+ Sbjct: 196 T-------------YSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQKGALQT 242 Query: 1159 HMGTH 1163 HM H Sbjct: 243 HMIKH 247 Score = 69.3 bits (168), Expect = 2e-11 Identities = 49/183 (26%), Positives = 75/183 (40%), Gaps = 45/183 (24%) Query: 979 CGVCGKPFACKSALEIHYRS-HTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037 C C + F+ + L H + H +ER C +CR+ +LK+H+ TH+ Sbjct: 1659 CLECDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQA-------- 1710 Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097 GPS +SS P + K + A + L ++ G Sbjct: 1711 ------GPS------LSSQKPRVFKCDTC----EKAFAKPSQLERHSRIHTGE------- 1747 Query: 1098 LAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLK 1157 + +C C K F+ SALQ+H + HTGE+P+ C C FT K N+K Sbjct: 1748 -------------RPFHCTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQKSNMK 1794 Query: 1158 VHM 1160 +HM Sbjct: 1795 LHM 1797 Score = 68.9 bits (167), Expect = 3e-11 Identities = 28/53 (52%), Positives = 36/53 (67%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 K + C CGK+F+ S L H +THTG+K F C +C AF+TKG+LKVHM H Sbjct: 1193 KPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLH 1245 Score = 68.6 bits (166), Expect = 4e-11 Identities = 84/381 (22%), Positives = 134/381 (35%), Gaps = 70/381 (18%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + E PF KC C + F S L+ H+R+HTG + FKC IC F+T G+L+ H H Sbjct: 680 TGEKPF---KCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHN 736 Query: 472 EKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLP 531 + P++ P C +K T L+ K + T + QL Sbjct: 737 DLRPYM-------------CPYC-----------QKTFKTSLNCKKHMKTHRYELAQQLQ 772 Query: 532 PTVPGA---HGYADSPSATPASR------SPQRPSPASSECASLSPGLNHVESGVSATAE 582 A D S +++ S + P A A+ L+ V T E Sbjct: 773 QHQQAASIDDSTVDQQSMQASTQMQVEIESDELPQTAEVVAANPEAMLDLEPQHVVGTEE 832 Query: 583 SP-QSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLG--------- 632 + L PL E + + G + S A S + A G Sbjct: 833 AGLGQQLADQPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQ 892 Query: 633 SPGLPAV----------SEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCV 682 P P V S+ F LL + + + +L++ ++ D Sbjct: 893 QPQFPPVQQLQDSSTLESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELD----- 947 Query: 683 ICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCP 742 L Q + + R ++C C + F +LK H H + P + C Sbjct: 948 -----LQAQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKP----YKCK 998 Query: 743 ICQKKFTNAVVLQQHIRMHMG 763 +C + F ++ VL+ H + H G Sbjct: 999 LCGRGFVSSGVLKSHEKTHTG 1019 Score = 67.8 bits (164), Expect = 7e-11 Identities = 27/54 (50%), Positives = 37/54 (68%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHM 1164 K + C+ CG+ F S+ L+ HE+THTG K F C++C +FTT G+L HM THM Sbjct: 993 KPYKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMATHM 1046 Score = 67.0 bits (162), Expect = 1e-10 Identities = 33/104 (31%), Positives = 49/104 (47%), Gaps = 4/104 (3%) Query: 662 SKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGN 721 S+L+ + + N C C + S L H R HTGE+P+KC CG++FT K Sbjct: 1150 SELRDKQAELQDEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKST 1209 Query: 722 LKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQ 765 L H H + SC +C F+ L+ H+R+H G + Sbjct: 1210 LDCHVKTHTGQK----LFSCHVCSNAFSTKGSLKVHMRLHTGAK 1249 Score = 63.9 bits (154), Expect = 9e-10 Identities = 28/64 (43%), Positives = 40/64 (62%), Gaps = 4/64 (6%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKE----KYP 475 +KC C K F S L H+++HTG++ F C++C N FSTKG+LKVH + H K P Sbjct: 1195 YKCDECGKSFTVKSTLDCHVKTHTGQKLFSCHVCSNAFSTKGSLKVHMRLHTGAKPFKCP 1254 Query: 476 HIQM 479 H ++ Sbjct: 1255 HCEL 1258 Score = 63.5 bits (153), Expect = 1e-09 Identities = 26/54 (48%), Positives = 34/54 (62%) Query: 1110 PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 P+ C +C K F+ S L+ H R HTGE+PF CT+C +AF K L+VHM H Sbjct: 1719 PRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMKKH 1772 Score = 63.2 bits (152), Expect = 2e-09 Identities = 29/70 (41%), Positives = 39/70 (55%), Gaps = 3/70 (4%) Query: 400 KPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFST 459 KP + + E PF C C K F SALQ+H++ HTGERP+KC C F+ Sbjct: 1733 KPSQLERHSRIHTGERPFH---CTLCEKAFNQKSALQVHMKKHTGERPYKCAYCVMGFTQ 1789 Query: 460 KGNLKVHFQR 469 K N+K+H +R Sbjct: 1790 KSNMKLHMKR 1799 Score = 61.2 bits (147), Expect = 6e-09 Identities = 47/188 (25%), Positives = 78/188 (41%), Gaps = 19/188 (10%) Query: 290 QPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQ--SAASSQPQSASTPPA-- 345 QPL E G P P +PA + PA PQ + + Q PP Sbjct: 842 QPLEADEDGFVAPQDPLRGHVDQFEEQSPAQQSFEPAGLPQGFTVTDTYHQQPQFPPVQQ 901 Query: 346 LAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVS 405 L S L ++ A F + A +++ ++ + L++ + ++ Sbjct: 902 LQDSSTL------------ESQALSTSFHQQSLLQAPSSDGMNVTTRLIQESSQEELDLQ 949 Query: 406 VFEPKA---SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462 + + + ++C +C K F S L+ H+RSHTGE+P+KC +CG F + G Sbjct: 950 AQGSQFLEDNEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGV 1009 Query: 463 LKVHFQRH 470 LK H + H Sbjct: 1010 LKSHEKTH 1017 Score = 60.5 bits (145), Expect = 1e-08 Identities = 64/241 (26%), Positives = 91/241 (37%), Gaps = 37/241 (15%) Query: 524 TSVGLQLP-----PTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVS 578 TS G Q P P++ G G A SP S +PQ S A E A G+ SG Sbjct: 1590 TSQGQQFPALLTDPSLSGQGG-AGSPQVILVSHTPQSASAACEEIAYQVAGV----SGNL 1644 Query: 579 ATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPA 638 A P+ L C A + A + + V G G P Sbjct: 1645 APGNQPEK-------EGRAHQCLECDRAFSSAAVLMHHSK----EVHGRERI---HGCPV 1690 Query: 639 VSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHY 698 + FK L + MQT + ++ + +C C + + S L+ H Sbjct: 1691 CRKAFKRATH---LKEHMQTHQAGP------SLSSQKPRVFKCDTCEKAFAKPSQLERHS 1741 Query: 699 RTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHI 758 R HTGERPF C +C +AF K L+ H H + P + C C FT ++ H+ Sbjct: 1742 RIHTGERPFHCTLCEKAFNQKSALQVHMKKHTGERP----YKCAYCVMGFTQKSNMKLHM 1797 Query: 759 R 759 + Sbjct: 1798 K 1798 Score = 60.5 bits (145), Expect = 1e-08 Identities = 28/68 (41%), Positives = 38/68 (55%), Gaps = 1/68 (1%) Query: 409 PKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQ 468 P S++ P KC C K F S L+ H R HTGERPF C +C F+ K L+VH + Sbjct: 1712 PSLSSQKPRV-FKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQKSALQVHMK 1770 Query: 469 RHKEKYPH 476 +H + P+ Sbjct: 1771 KHTGERPY 1778 Score = 59.7 bits (143), Expect = 2e-08 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 1/93 (1%) Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736 DP C +C++ S ++LK H H E C CG FT + L H HR + Sbjct: 92 DPT-CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGT 150 Query: 737 VQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNT 769 QH+C C+K+F + L++H++ H ++ +T Sbjct: 151 RQHACKACKKEFETSSELKEHMKTHYKIRVSST 183 Score = 58.5 bits (140), Expect = 4e-08 Identities = 23/51 (45%), Positives = 33/51 (64%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 +KC +C + + L+ H+RSHTGE+PFKC+ CG F + G LK H + H Sbjct: 657 YKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTH 707 Score = 58.2 bits (139), Expect = 5e-08 Identities = 50/199 (25%), Positives = 72/199 (36%), Gaps = 33/199 (16%) Query: 305 PAEPSAPAAPSAAPAPAAPAPAPAPQSAAS-SQPQSASTPPALAPGSLLGAAPGLPSPLL 363 P + + A SA+ P++ A + Q S+P + + PG L G+ +L Sbjct: 334 PLQQTEAQATSASSQPSSQAVSDVIQQLLELSEPAPVESGQSPQPGQQLSITVGINQDIL 393 Query: 364 PQ-------TSASGVIFPNPLVSIAATA-------------NALDPLSALMKHRKGKPPN 403 Q +S PN +A DP A + + P Sbjct: 394 QQALENSGLSSIPAAAHPNDSCHAKTSAPHAQNPDVSSVSNEQTDPTDAEQEKEQESPEK 453 Query: 404 VSVFEPKA-SAEDPFFK-----------HKCRFCAKVFGSDSALQIHLRSHTGERPFKCN 451 + E K + PF H C +CAK F S L H+R HT E+PFKC Sbjct: 454 LDKKEKKMIKKKSPFLPGSIREENGVRWHVCPYCAKEFRKPSDLVRHIRIHTHEKPFKCP 513 Query: 452 ICGNRFSTKGNLKVHFQRH 470 C F+ K L H + H Sbjct: 514 QCFRAFAVKSTLTAHIKTH 532 Score = 57.4 bits (137), Expect = 9e-08 Identities = 24/60 (40%), Positives = 32/60 (53%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481 C C+ F + +L++H+R HTG +PFKC C RF T G K H Q H + P P Sbjct: 1225 CHVCSNAFSTKGSLKVHMRLHTGAKPFKCPHCELRFRTSGRRKTHMQFHYKPDPKKARKP 1284 Score = 55.8 bits (133), Expect = 3e-07 Identities = 23/57 (40%), Positives = 33/57 (57%) Query: 414 EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 ++P + C +C K F S L H+R HTGE+P+KC+ CG F+ K L H + H Sbjct: 1161 DEPKHANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTH 1217 Score = 55.5 bits (132), Expect = 3e-07 Identities = 63/299 (21%), Positives = 108/299 (36%), Gaps = 41/299 (13%) Query: 495 SGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQ 554 SG P+ ++L + + ++ PT +S G P + ++ S + S +P Sbjct: 1487 SGGPHEITLTINNSSLSQVLAQAAGPTATSSSGS--PQEITLTISELNTTSGSLPSTTPM 1544 Query: 555 RPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTN------ARA 608 PS S++ +S ++ V+ T Q +L G + V+L T+ A Sbjct: 1545 SPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGG----LDTVTLNITSQGQQFPALL 1600 Query: 609 GDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLV 668 D + Q A V + S ++ G L Q + + Q + Sbjct: 1601 TDPSLSGQGGAGSPQVILVSHTPQSASAACEEIAYQVAGVSGNLAPGNQPEKEGRAHQCL 1660 Query: 669 ENIDKKMTDP----------------NQCVICHRVLSCQSALKMHYRTHTG--------E 704 E D+ + + C +C + + LK H +TH Sbjct: 1661 E-CDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKP 1719 Query: 705 RPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 R FKC C +AF L+ H +H + P C +C+K F LQ H++ H G Sbjct: 1720 RVFKCDTCEKAFAKPSQLERHSRIHTGERPFH----CTLCEKAFNQKSALQVHMKKHTG 1774 Score = 53.9 bits (128), Expect = 1e-06 Identities = 24/57 (42%), Positives = 30/57 (52%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736 +C C + S +LK+H R HTG RPF C C + F T G+ KTH H LR Sbjct: 539 KCQYCMKSFSTSGSLKVHIRLHTGVRPFACPHCDKKFRTSGHRKTHIASHFKHTELR 595 Score = 53.9 bits (128), Expect = 1e-06 Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 6/66 (9%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQM 479 +KC+ C + F S L+ H ++HTG + F C++C F+T G+L H H+ M Sbjct: 995 YKCKLCGRGFVSSGVLKSHEKTHTGVKAFSCSVCNASFTTNGSLTRHMA------THMSM 1048 Query: 480 NPYPVP 485 PY P Sbjct: 1049 KPYKCP 1054 Score = 48.5 bits (114), Expect = 4e-05 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Query: 1108 RTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 R K H C C +TF+ L +H+ TH+GE P C +C + F+ +LK H+ H Sbjct: 61 RNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRVASLKAHIMLH 115 Score = 47.8 bits (112), Expect = 7e-05 Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 4/60 (6%) Query: 704 ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 +RP+KC C RA+ +LK H H + P + C C + F +A VL+ HIR H G Sbjct: 654 DRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFK----CSQCGRGFVSAGVLKAHIRTHTG 709 Score = 47.8 bits (112), Expect = 7e-05 Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037 C C + + L+ H RSHT E+PF C+ C RG + G LK H+ TH LK + Sbjct: 659 CFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRGFVSAGVLKAHIRTHTGLKSFKCLIC 718 Query: 1038 DPNFALGPS 1046 + F G S Sbjct: 719 NGAFTTGGS 727 Score = 47.8 bits (112), Expect = 7e-05 Identities = 59/241 (24%), Positives = 90/241 (37%), Gaps = 31/241 (12%) Query: 541 ADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVS 600 A P+AT +S SPQ + SE + S L P T P + Sbjct: 1509 AAGPTATSSSGSPQEITLTISELNTTSGSL--------------------PSTTPMSPSA 1548 Query: 601 LPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFP-FGGLLD----S 655 + N + VG AS T D + S GL V+ +Q F LL S Sbjct: 1549 ISTQNLVMSSSGVGGDASVTLTLAD--TQGMLSGGLDTVTLNITSQGQQFPALLTDPSLS 1606 Query: 656 MQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRA 715 Q S LV + + + + I ++V L + R +C C RA Sbjct: 1607 GQGGAGSPQVILVSHTPQSASAACE-EIAYQVAGVSGNLAPGNQPEKEGRAHQCLECDRA 1665 Query: 716 FTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGF 775 F++ L H + + H CP+C+K F A L++H++ H G ++ P F Sbjct: 1666 FSSAAVLMHHSKEVHGRERI---HGCPVCRKAFKRATHLKEHMQTHQAGPSLSSQKPRVF 1722 Query: 776 Q 776 + Sbjct: 1723 K 1723 Score = 47.4 bits (111), Expect = 9e-05 Identities = 32/102 (31%), Positives = 39/102 (38%), Gaps = 22/102 (21%) Query: 681 CVICHRVLSCQSALKMHYRTH----TGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736 C C + QS L +H H G R CK C + F T LK H H +R Sbjct: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTHYK---IR 179 Query: 737 VQ---------------HSCPICQKKFTNAVVLQQHIRMHMG 763 V +SCP C K F L +HIR+H G Sbjct: 180 VSSTRSYNRNIDRSGFTYSCPHCGKTFQKPSQLTRHIRIHTG 221 Score = 45.1 bits (105), Expect = 5e-04 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 4/71 (5%) Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462 N+++ + S EDP C C K F ++L+ H+ H E C+ CG+ F+ + Sbjct: 80 NLTLHKCTHSGEDP----TCPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQ 135 Query: 463 LKVHFQRHKEK 473 L VH + H+++ Sbjct: 136 LAVHMEEHRQE 146 Score = 42.7 bits (99), Expect = 0.002 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 1/57 (1%) Query: 420 HKCRFCAKVFGSDSALQIHLRSH-TGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475 HKC C F +S Q H+R H ++P +C+ C F+ + NL +H H + P Sbjct: 37 HKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDP 93 Score = 42.7 bits (99), Expect = 0.002 Identities = 21/58 (36%), Positives = 28/58 (48%) Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARR 1172 C C K FS ++L+ H H E+ C+ CG FT + L VHM H A R+ Sbjct: 95 CPVCNKKFSRVASLKAHIMLHEKEENLICSECGDEFTLQSQLAVHMEEHRQELAGTRQ 152 Score = 42.4 bits (98), Expect = 0.003 Identities = 52/228 (22%), Positives = 87/228 (38%), Gaps = 13/228 (5%) Query: 254 APSQLPGLAALPLSAGAPAAAIA-GSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPA 312 +PS P L ++ + + +A +GP A ++ Q ++ S +T G + P Sbjct: 1485 SPSGGPHEITLTINNSSLSQVLAQAAGPTATSSSGSPQEITLTISELNTTSGSLPSTTPM 1544 Query: 313 APSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPG----SLLGAAPGLPSPLL---PQ 365 +PSA + AS A T L+ G +L + G P L P Sbjct: 1545 SPSAISTQNLVMSSSGVGGDASVTLTLADTQGMLSGGLDTVTLNITSQGQQFPALLTDPS 1604 Query: 366 TSASGVIFPNPLVSIAATANALDPLSALMKHR-KGKPPNVSVFEPKASAEDPFFKHKCRF 424 S G ++ ++ T + + ++ G N++ P E H+C Sbjct: 1605 LSGQGGAGSPQVILVSHTPQSASAACEEIAYQVAGVSGNLA---PGNQPEKEGRAHQCLE 1661 Query: 425 CAKVFGSDSALQIHLRS-HTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 C + F S + L H + H ER C +C F +LK H Q H+ Sbjct: 1662 CDRAFSSAAVLMHHSKEVHGRERIHGCPVCRKAFKRATHLKEHMQTHQ 1709 Score = 41.2 bits (95), Expect = 0.007 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Query: 1108 RTPKQHNCQSCGKTFSSASALQIHERTH-TGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 + P H C+ C +F S Q H R H +KP C C + F + NL +H TH Sbjct: 32 QVPNFHKCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTH 88 Score = 40.8 bits (94), Expect = 0.009 Identities = 16/50 (32%), Positives = 26/50 (52%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 C C F ++ +L H+ +H +P+KC C F T + K H +RH+ Sbjct: 1025 CSVCNASFTTNGSLTRHMATHMSMKPYKCPFCEEGFRTTVHCKKHMKRHQ 1074 Score = 38.1 bits (87), Expect = 0.055 Identities = 19/54 (35%), Positives = 26/54 (48%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKEL 1032 C C K F S L H R HT E+P+ C C + + L H+ TH ++L Sbjct: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKL 1222 Score = 36.6 bits (83), Expect = 0.16 Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 2/74 (2%) Query: 958 EEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTM 1017 +E+ F ER P C C + F + L +H +H+ E P C +C + S + Sbjct: 48 KESQFQRHMRDHERNDKPHR-CDQCPQTFNVEFNLTLHKCTHSGEDP-TCPVCNKKFSRV 105 Query: 1018 GNLKQHLLTHRLKE 1031 +LK H++ H +E Sbjct: 106 ASLKAHIMLHEKEE 119 Score = 35.8 bits (81), Expect = 0.27 Identities = 17/53 (32%), Positives = 20/53 (37%), Gaps = 4/53 (7%) Query: 422 CRFCAKVFGSDSALQIHLRSH----TGERPFKCNICGNRFSTKGNLKVHFQRH 470 C C F S L +H+ H G R C C F T LK H + H Sbjct: 123 CSECGDEFTLQSQLAVHMEEHRQELAGTRQHACKACKKEFETSSELKEHMKTH 175 Score = 35.4 bits (80), Expect = 0.36 Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 4/58 (6%) Query: 709 CKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQI 766 C C ++F +L H +H + P + C C K FT L H++ H G ++ Sbjct: 1169 CTYCPKSFKKPSDLVRHVRIHTGEKP----YKCDECGKSFTVKSTLDCHVKTHTGQKL 1222 Score = 32.0 bits (71), Expect = 4.0 Identities = 20/78 (25%), Positives = 29/78 (37%), Gaps = 24/78 (30%) Query: 708 KCKICGRAFTTKGNLKTHFGVH-RAKPPLRVQH-----------------------SCPI 743 KC+IC +F + + H H R P R +CP+ Sbjct: 38 KCEICLLSFPKESQFQRHMRDHERNDKPHRCDQCPQTFNVEFNLTLHKCTHSGEDPTCPV 97 Query: 744 CQKKFTNAVVLQQHIRMH 761 C KKF+ L+ HI +H Sbjct: 98 CNKKFSRVASLKAHIMLH 115 >gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo sapiens] Length = 1059 Score = 131 bits (329), Expect = 5e-30 Identities = 236/1025 (23%), Positives = 329/1025 (32%), Gaps = 236/1025 (23%) Query: 184 GARAAGGSGAGG--GVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQ---RPPP 238 GA G SG GG GV + P + L L Q+ ++L + VA + PPP Sbjct: 9 GAGGGGSSGIGGEDGVHFQSYPF--DFLEFLNHQRFEPMELYGEHAKAVAALPCAPGPPP 66 Query: 239 RPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESG 298 +P P P P P P S P A + S ++ ++ + S S Sbjct: 67 QP-------PPQPPPPQYDYP-----PQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSS 114 Query: 299 ASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAA---SSQPQSASTPPALAPGSLLGAA 355 +S+ +P P A A P P A P PQ S P S G Sbjct: 115 SSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVT 174 Query: 356 PGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAED 415 PGL +P A A PL A + G PP + +P + Sbjct: 175 PGLGAP----------------------AGAPGPLPAPSQTPPG-PPAAAACDPTKDDKG 211 Query: 416 PFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475 F + K + ER F C +C F +L H H + P Sbjct: 212 YFRRLK--------------------YLMERRFPCGVCQKSFKQSSHLVQHMLVHSGERP 251 Query: 476 HIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVP 535 + G+ V++ + + VP + G P P Sbjct: 252 Y---------------------ECGVCGRTYNHVSSLIRHRRCHKDVPPAAG---GPPQP 287 Query: 536 GAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTK 595 G H P PA PA+S +ATA +P ++ GPP T Sbjct: 288 GPHL---PPLGLPA--------PAAS----------------AATAAAPSTVSSGPPATP 320 Query: 596 AEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDS 655 P AP A SAAP V P + G GG Sbjct: 321 VAP------------AP-SADGSAAPAGVGVPPPATG-----------------GG---- 346 Query: 656 MQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRA 715 P C +C +V S L H HTGE+PF C +C ++ Sbjct: 347 --------------------DGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKS 386 Query: 716 FTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMH----MGGQIPNTP- 770 F + +LK H H A ++ C IC K F +A L +H H GG P P Sbjct: 387 FNRRESLKRHVKTHSAD---LLRLPCGICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPC 443 Query: 771 -LPEGFQDAMDSELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGS- 828 L A S L + +A ++ + D AA+ P P G Sbjct: 444 DLCGKSYSAPQSLLRHKAAHAPPAAAAEAPKD-----------GAASAPQPPPTFPPGPY 492 Query: 829 -CPPSPPSVISSIAALENQMKMIDSV----MSCQQLT---GLKSVENGSGESDRLSNDSS 880 PP PP+ S AA + +V + L S GSG S Sbjct: 493 LLPPDPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCC 552 Query: 881 SAVGDLESRSAGSPALSESSSSQALSPAPSNGESFR-----SKSPGLGAPEEPQEIPL-- 933 G R + + P G+ FR SK + E P + L Sbjct: 553 GICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCELCG 612 Query: 934 -------------KTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCG 980 + R P A G+ G P G S S C Sbjct: 613 KVFGYPQSLTRHRQVHRLQLPCALAGAAGLPSTQGTPGACGPGASGTSAGPTDGLSYACS 672 Query: 981 VCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPN 1040 CG+ F + H H E+P+ C C + + NL H L H + P +L P Sbjct: 673 DCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLVH--QAAPERLLPP- 729 Query: 1041 FALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQ--VPAGPQTVMGPGL 1098 P P SS V +G A +G AGV AG V G G Sbjct: 730 ---APGGLQPPDGSSGTDA---ASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAVAGAGG 783 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 P++ +C +CG++F L H+ H + GC +CG++F +L + Sbjct: 784 GASSG------PERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLL 837 Query: 1159 HMGTH 1163 H +H Sbjct: 838 HRRSH 842 Score = 111 bits (278), Expect = 4e-24 Identities = 168/753 (22%), Positives = 238/753 (31%), Gaps = 184/753 (24%) Query: 37 ADSGPESRSGGEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDA---------P 87 A G S GGE+ + +F +FL HQR P+ + E A P Sbjct: 10 AGGGGSSGIGGEDGVHFQSYPFDFL---EFLNHQR----FEPMELYGEHAKAVAALPCAP 62 Query: 88 APPPEDFPEPSPA--SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAP 145 PPP+ P+P P P + AE + + + + + + + P Sbjct: 63 GPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKP 122 Query: 146 RP--PPAAPAPPTPAYGA--PSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAA 201 P PPA APP P + A P+ + L + +G A+G G A A Sbjct: 123 DPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVTPGLGAPAG 182 Query: 202 VPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPS----- 256 P P P PS +P P+A P+ Sbjct: 183 AP-------------------------------GPLPAPSQTPPGPPAAAACDPTKDDKG 211 Query: 257 ---QLPGLAALPLSAGAPAAAIAGSGPAAP--AAFEGAQPLSRPESGAS----------- 300 +L L G + S G +P G + Sbjct: 212 YFRRLKYLMERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHR 271 Query: 301 --------TPGGPAEPSAPAAPSAAPAPAA-PAPAPAPQSAASSQPQSASTPPALAPGSL 351 GGP +P P PAPAA A A AP + +S P + P A GS Sbjct: 272 RCHKDVPPAAGGPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSA 331 Query: 352 LGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKA 411 A G+P P A+G Sbjct: 332 APAGVGVPPP------ATG----------------------------------------- 344 Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + PF C C KVF S L H HTGE+PF C++C F+ + +LK H + H Sbjct: 345 GGDGPF---ACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHS 401 Query: 472 EKYPHIQMN---------PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTV 522 + Y + + +G P +PV P Sbjct: 402 ADLLRLPCGICGKAFRDASYLLKHQAAHAGAGAGGP-----------------RPVYPCD 444 Query: 523 PTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAE 582 P ++ H A +P A A + A + PG Sbjct: 445 LCGKSYSAPQSLL-RHKAAHAPPAAAAEAPKDGAASAPQPPPTFPPG------------- 490 Query: 583 SPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTS-LGSPGLPAVSE 641 P L PP T +E + G PV A P + GA TS G G + Sbjct: 491 -PYLLPPDPPTTDSEKAAAAAAAVVYGAVPV-PLLGAHPLLLGGAGTSGAGGSGASVPGK 548 Query: 642 QFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTH 701 F G ET K + + +K P+QC +C + L H+ H Sbjct: 549 TFCCGICGRG----FGRRETLKRHERIHTGEK----PHQCPVCGKRFRESFHLSKHHVVH 600 Query: 702 TGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734 T ERP+KC++CG+ F +L H VHR + P Sbjct: 601 TRERPYKCELCGKVFGYPQSLTRHRQVHRLQLP 633 Score = 92.8 bits (229), Expect = 2e-18 Identities = 164/674 (24%), Positives = 225/674 (33%), Gaps = 122/674 (18%) Query: 147 PPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGA-----GGGVAAAA 201 PP PAP A A + + +T VA A + G+ A G G GGG A Sbjct: 292 PPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFA 351 Query: 202 VPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGL 261 PL + + +HQ Q+I + S S S + L Sbjct: 352 CPLCWKVFK--KPSHLHQHQIIHTGEKPFSCSVC-----SKSFNRRESLKRHVKTHSADL 404 Query: 262 AALPLSAGAPA-----------AAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSA 310 LP A AA AG+G P P S P A Sbjct: 405 LRLPCGICGKAFRDASYLLKHQAAHAGAGAGGPRP---VYPCDLCGKSYSAPQSLLRHKA 461 Query: 311 PAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASG 370 AP PAA A AP +A++ QP PP PG P L P P T + Sbjct: 462 AHAP-----PAAAAEAPKDGAASAPQP-----PPTFPPG------PYLLPPDPPTTDSE- 504 Query: 371 VIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFG 430 + AA P+ L H + + A P C C + FG Sbjct: 505 ----KAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCCGICGRGFG 560 Query: 431 SDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDN 490 L+ H R HTGE+P +C +CG RF +L H H + P+ Sbjct: 561 RRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPY-------------K 607 Query: 491 VPTCSGI-PYGMSLPPEKPVTTWLDSKPVLP-TVPTSVGLQLPPTVPGAHGYADSPSATP 548 C + Y SL + V + LP + + GL PGA G P A+ Sbjct: 608 CELCGKVFGYPQSLTRHRQV-----HRLQLPCALAGAAGLPSTQGTPGACG----PGASG 658 Query: 549 ASRSPQRP-SPASSECASLSPGLNHVES-----------GVSATAES------------- 583 S P S A S+C P L HV S G A ++ Sbjct: 659 TSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLV 718 Query: 584 ----PQSLL----GG---PPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVD---GAPT 629 P+ LL GG P + + N AG+ A A + + GA Sbjct: 719 HQAAPERLLPPAPGGLQPPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAV 778 Query: 630 SLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLS 689 + G + E+F G T K LV C +C + + Sbjct: 779 AGAGGGASSGPERFSCA-TCGQSFKHFLGLVTHKYVHLVRRT-------LGCGLCGQSFA 830 Query: 690 CQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFT 749 L +H R+H +R F+C +CG+ F L H H + P R C +C + F Sbjct: 831 GAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYR----CGVCGRGFL 886 Query: 750 NAVVLQQHIRMHMG 763 + L+QH +H G Sbjct: 887 RSWYLRQHRVVHTG 900 Score = 62.4 bits (150), Expect = 3e-09 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + +S L H R H GER ++C+ CG+ F ++ H RA P R Sbjct: 931 PQRCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRH---QRAHEPPRA 987 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQ 765 + CP C K F + ++H+ H GG+ Sbjct: 988 ELRCPACLKAFKDPGYFRKHLAAHQGGR 1015 Score = 59.3 bits (142), Expect = 2e-08 Identities = 59/226 (26%), Positives = 80/226 (35%), Gaps = 15/226 (6%) Query: 952 GRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCR 1011 G G + LL R + C VCGK F + L H R HT++RP+ C +C Sbjct: 823 GLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCG 882 Query: 1012 RGCSTMGNLKQHLLTHR-LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGK 1070 RG L+QH + H + + FA S + + + A + GK Sbjct: 883 RGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVAR---PQRCSACGK 939 Query: 1071 AMA----LGEGPPLPAGVQVPAGPQTVMG-----PGLAPMLAPPPRRTPKQHNCQSCGKT 1121 L E L G + G L A P R + C +C K Sbjct: 940 TFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHEPPRA--ELRCPACLKA 997 Query: 1122 FSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNN 1167 F + H H G +PF C+ CG F LK H H N Sbjct: 998 FKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAEN 1043 Score = 58.5 bits (140), Expect = 4e-08 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C +C R L+ H HTGER FKC +C + F +L H +H P R Sbjct: 875 PYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQR- 933 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 C C K F L +H R+H+G Sbjct: 934 ---CSACGKTFRYRSNLLEHQRLHLG 956 Score = 57.8 bits (138), Expect = 7e-08 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 +C +C + + L H R HT +RP++C +CGR F L+ H VH + + Sbjct: 849 RCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFK--- 905 Query: 740 SCPICQKKFTNAVVLQQHIRMH 761 C +C K+F + L +H R+H Sbjct: 906 -CGVCAKRFAQSSSLAEHRRLH 926 Score = 49.7 bits (117), Expect = 2e-05 Identities = 24/67 (35%), Positives = 33/67 (49%) Query: 405 SVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLK 464 SV + + E P + +C C K F + HL +H G RPF+C+ CG F+ LK Sbjct: 974 SVLRHQRAHEPPRAELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLK 1033 Query: 465 VHFQRHK 471 H HK Sbjct: 1034 KHRLAHK 1040 Score = 45.8 bits (107), Expect = 3e-04 Identities = 21/50 (42%), Positives = 26/50 (52%) Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 KC CAK F S+L H R H RP +C+ CG F + NL H + H Sbjct: 905 KCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLH 954 Score = 45.1 bits (105), Expect = 5e-04 Identities = 19/54 (35%), Positives = 27/54 (50%) Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168 C C K F+ +S+L H R H +P C+ CG+ F + NL H H+ A Sbjct: 906 CGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERA 959 Score = 44.3 bits (103), Expect = 8e-04 Identities = 20/56 (35%), Positives = 28/56 (50%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475 ++C C + F L+ H HTGER FKC +C RF+ +L H + H P Sbjct: 876 YRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARP 931 Score = 41.2 bits (95), Expect = 0.007 Identities = 17/53 (32%), Positives = 23/53 (43%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAK 732 +C C + + H H G RPF+C CG F LK H H+A+ Sbjct: 990 RCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAE 1042 Score = 38.9 bits (89), Expect = 0.032 Identities = 18/51 (35%), Positives = 25/51 (49%) Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 +C C K F S L H R H GER ++C CG F ++ H + H+ Sbjct: 933 RCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHE 983 Score = 38.1 bits (87), Expect = 0.055 Identities = 18/54 (33%), Positives = 24/54 (44%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKEL 1032 C C K F H +H RPF C+ C G + LK+H L H+ + L Sbjct: 991 CPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAENL 1044 >gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo sapiens] Length = 1059 Score = 131 bits (329), Expect = 5e-30 Identities = 236/1025 (23%), Positives = 329/1025 (32%), Gaps = 236/1025 (23%) Query: 184 GARAAGGSGAGG--GVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQ---RPPP 238 GA G SG GG GV + P + L L Q+ ++L + VA + PPP Sbjct: 9 GAGGGGSSGIGGEDGVHFQSYPF--DFLEFLNHQRFEPMELYGEHAKAVAALPCAPGPPP 66 Query: 239 RPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESG 298 +P P P P P P S P A + S ++ ++ + S S Sbjct: 67 QP-------PPQPPPPQYDYP-----PQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSS 114 Query: 299 ASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAA---SSQPQSASTPPALAPGSLLGAA 355 +S+ +P P A A P P A P PQ S P S G Sbjct: 115 SSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVT 174 Query: 356 PGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAED 415 PGL +P A A PL A + G PP + +P + Sbjct: 175 PGLGAP----------------------AGAPGPLPAPSQTPPG-PPAAAACDPTKDDKG 211 Query: 416 PFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475 F + K + ER F C +C F +L H H + P Sbjct: 212 YFRRLK--------------------YLMERRFPCGVCQKSFKQSSHLVQHMLVHSGERP 251 Query: 476 HIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVP 535 + G+ V++ + + VP + G P P Sbjct: 252 Y---------------------ECGVCGRTYNHVSSLIRHRRCHKDVPPAAG---GPPQP 287 Query: 536 GAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTK 595 G H P PA PA+S +ATA +P ++ GPP T Sbjct: 288 GPHL---PPLGLPA--------PAAS----------------AATAAAPSTVSSGPPATP 320 Query: 596 AEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDS 655 P AP A SAAP V P + G GG Sbjct: 321 VAP------------AP-SADGSAAPAGVGVPPPATG-----------------GG---- 346 Query: 656 MQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRA 715 P C +C +V S L H HTGE+PF C +C ++ Sbjct: 347 --------------------DGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKS 386 Query: 716 FTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMH----MGGQIPNTP- 770 F + +LK H H A ++ C IC K F +A L +H H GG P P Sbjct: 387 FNRRESLKRHVKTHSAD---LLRLPCGICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPC 443 Query: 771 -LPEGFQDAMDSELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGS- 828 L A S L + +A ++ + D AA+ P P G Sbjct: 444 DLCGKSYSAPQSLLRHKAAHAPPAAAAEAPKD-----------GAASAPQPPPTFPPGPY 492 Query: 829 -CPPSPPSVISSIAALENQMKMIDSV----MSCQQLT---GLKSVENGSGESDRLSNDSS 880 PP PP+ S AA + +V + L S GSG S Sbjct: 493 LLPPDPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCC 552 Query: 881 SAVGDLESRSAGSPALSESSSSQALSPAPSNGESFR-----SKSPGLGAPEEPQEIPL-- 933 G R + + P G+ FR SK + E P + L Sbjct: 553 GICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCELCG 612 Query: 934 -------------KTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCG 980 + R P A G+ G P G S S C Sbjct: 613 KVFGYPQSLTRHRQVHRLQLPCALAGAAGLPSTQGTPGACGPGASGTSAGPTDGLSYACS 672 Query: 981 VCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPN 1040 CG+ F + H H E+P+ C C + + NL H L H + P +L P Sbjct: 673 DCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLVH--QAAPERLLPP- 729 Query: 1041 FALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQ--VPAGPQTVMGPGL 1098 P P SS V +G A +G AGV AG V G G Sbjct: 730 ---APGGLQPPDGSSGTDA---ASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAVAGAGG 783 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 P++ +C +CG++F L H+ H + GC +CG++F +L + Sbjct: 784 GASSG------PERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLL 837 Query: 1159 HMGTH 1163 H +H Sbjct: 838 HRRSH 842 Score = 111 bits (278), Expect = 4e-24 Identities = 168/753 (22%), Positives = 238/753 (31%), Gaps = 184/753 (24%) Query: 37 ADSGPESRSGGEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDA---------P 87 A G S GGE+ + +F +FL HQR P+ + E A P Sbjct: 10 AGGGGSSGIGGEDGVHFQSYPFDFL---EFLNHQR----FEPMELYGEHAKAVAALPCAP 62 Query: 88 APPPEDFPEPSPA--SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAP 145 PPP+ P+P P P + AE + + + + + + + P Sbjct: 63 GPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKP 122 Query: 146 RP--PPAAPAPPTPAYGA--PSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAA 201 P PPA APP P + A P+ + L + +G A+G G A A Sbjct: 123 DPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVTPGLGAPAG 182 Query: 202 VPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPS----- 256 P P P PS +P P+A P+ Sbjct: 183 AP-------------------------------GPLPAPSQTPPGPPAAAACDPTKDDKG 211 Query: 257 ---QLPGLAALPLSAGAPAAAIAGSGPAAP--AAFEGAQPLSRPESGAS----------- 300 +L L G + S G +P G + Sbjct: 212 YFRRLKYLMERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHR 271 Query: 301 --------TPGGPAEPSAPAAPSAAPAPAA-PAPAPAPQSAASSQPQSASTPPALAPGSL 351 GGP +P P PAPAA A A AP + +S P + P A GS Sbjct: 272 RCHKDVPPAAGGPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSA 331 Query: 352 LGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKA 411 A G+P P A+G Sbjct: 332 APAGVGVPPP------ATG----------------------------------------- 344 Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + PF C C KVF S L H HTGE+PF C++C F+ + +LK H + H Sbjct: 345 GGDGPF---ACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHS 401 Query: 472 EKYPHIQMN---------PYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTV 522 + Y + + +G P +PV P Sbjct: 402 ADLLRLPCGICGKAFRDASYLLKHQAAHAGAGAGGP-----------------RPVYPCD 444 Query: 523 PTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAE 582 P ++ H A +P A A + A + PG Sbjct: 445 LCGKSYSAPQSLL-RHKAAHAPPAAAAEAPKDGAASAPQPPPTFPPG------------- 490 Query: 583 SPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTS-LGSPGLPAVSE 641 P L PP T +E + G PV A P + GA TS G G + Sbjct: 491 -PYLLPPDPPTTDSEKAAAAAAAVVYGAVPV-PLLGAHPLLLGGAGTSGAGGSGASVPGK 548 Query: 642 QFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTH 701 F G ET K + + +K P+QC +C + L H+ H Sbjct: 549 TFCCGICGRG----FGRRETLKRHERIHTGEK----PHQCPVCGKRFRESFHLSKHHVVH 600 Query: 702 TGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734 T ERP+KC++CG+ F +L H VHR + P Sbjct: 601 TRERPYKCELCGKVFGYPQSLTRHRQVHRLQLP 633 Score = 92.8 bits (229), Expect = 2e-18 Identities = 164/674 (24%), Positives = 225/674 (33%), Gaps = 122/674 (18%) Query: 147 PPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGA-----GGGVAAAA 201 PP PAP A A + + +T VA A + G+ A G G GGG A Sbjct: 292 PPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFA 351 Query: 202 VPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGL 261 PL + + +HQ Q+I + S S S + L Sbjct: 352 CPLCWKVFK--KPSHLHQHQIIHTGEKPFSCSVC-----SKSFNRRESLKRHVKTHSADL 404 Query: 262 AALPLSAGAPA-----------AAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSA 310 LP A AA AG+G P P S P A Sbjct: 405 LRLPCGICGKAFRDASYLLKHQAAHAGAGAGGPRP---VYPCDLCGKSYSAPQSLLRHKA 461 Query: 311 PAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASG 370 AP PAA A AP +A++ QP PP PG P L P P T + Sbjct: 462 AHAP-----PAAAAEAPKDGAASAPQP-----PPTFPPG------PYLLPPDPPTTDSE- 504 Query: 371 VIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFG 430 + AA P+ L H + + A P C C + FG Sbjct: 505 ----KAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSGAGGSGASVPGKTFCCGICGRGFG 560 Query: 431 SDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDN 490 L+ H R HTGE+P +C +CG RF +L H H + P+ Sbjct: 561 RRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPY-------------K 607 Query: 491 VPTCSGI-PYGMSLPPEKPVTTWLDSKPVLP-TVPTSVGLQLPPTVPGAHGYADSPSATP 548 C + Y SL + V + LP + + GL PGA G P A+ Sbjct: 608 CELCGKVFGYPQSLTRHRQV-----HRLQLPCALAGAAGLPSTQGTPGACG----PGASG 658 Query: 549 ASRSPQRP-SPASSECASLSPGLNHVES-----------GVSATAES------------- 583 S P S A S+C P L HV S G A ++ Sbjct: 659 TSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIENLMWHKLV 718 Query: 584 ----PQSLL----GG---PPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVD---GAPT 629 P+ LL GG P + + N AG+ A A + + GA Sbjct: 719 HQAAPERLLPPAPGGLQPPDGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAV 778 Query: 630 SLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLS 689 + G + E+F G T K LV C +C + + Sbjct: 779 AGAGGGASSGPERFSCA-TCGQSFKHFLGLVTHKYVHLVRRT-------LGCGLCGQSFA 830 Query: 690 CQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFT 749 L +H R+H +R F+C +CG+ F L H H + P R C +C + F Sbjct: 831 GAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYR----CGVCGRGFL 886 Query: 750 NAVVLQQHIRMHMG 763 + L+QH +H G Sbjct: 887 RSWYLRQHRVVHTG 900 Score = 61.6 bits (148), Expect = 5e-09 Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 3/88 (3%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + +S L H R H GER ++C+ CG+ F ++ H RA P R Sbjct: 931 PQRCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRH---QRAHEPPRP 987 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQ 765 + CP C K F + ++H+ H GG+ Sbjct: 988 ELRCPACLKAFKDPGYFRKHLAAHQGGR 1015 Score = 58.9 bits (141), Expect = 3e-08 Identities = 59/226 (26%), Positives = 80/226 (35%), Gaps = 15/226 (6%) Query: 952 GRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCR 1011 G G + LL R + C VCGK F + L H R HT++RP+ C +C Sbjct: 823 GLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCG 882 Query: 1012 RGCSTMGNLKQHLLTHR-LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGK 1070 RG L+QH + H + + FA S + + + A + GK Sbjct: 883 RGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVAR---PQRCSACGK 939 Query: 1071 AMA----LGEGPPLPAGVQVPAGPQTVMG-----PGLAPMLAPPPRRTPKQHNCQSCGKT 1121 L E L G + G L A P R + C +C K Sbjct: 940 TFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHEPPR--PELRCPACLKA 997 Query: 1122 FSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNN 1167 F + H H G +PF C+ CG F LK H H N Sbjct: 998 FKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAEN 1043 Score = 58.5 bits (140), Expect = 4e-08 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C +C R L+ H HTGER FKC +C + F +L H +H P R Sbjct: 875 PYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQR- 933 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 C C K F L +H R+H+G Sbjct: 934 ---CSACGKTFRYRSNLLEHQRLHLG 956 Score = 57.8 bits (138), Expect = 7e-08 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 +C +C + + L H R HT +RP++C +CGR F L+ H VH + + Sbjct: 849 RCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFK--- 905 Query: 740 SCPICQKKFTNAVVLQQHIRMH 761 C +C K+F + L +H R+H Sbjct: 906 -CGVCAKRFAQSSSLAEHRRLH 926 Score = 48.9 bits (115), Expect = 3e-05 Identities = 24/67 (35%), Positives = 33/67 (49%) Query: 405 SVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLK 464 SV + + E P + +C C K F + HL +H G RPF+C+ CG F+ LK Sbjct: 974 SVLRHQRAHEPPRPELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLK 1033 Query: 465 VHFQRHK 471 H HK Sbjct: 1034 KHRLAHK 1040 Score = 45.8 bits (107), Expect = 3e-04 Identities = 21/50 (42%), Positives = 26/50 (52%) Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 KC CAK F S+L H R H RP +C+ CG F + NL H + H Sbjct: 905 KCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLH 954 Score = 45.1 bits (105), Expect = 5e-04 Identities = 19/54 (35%), Positives = 27/54 (50%) Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168 C C K F+ +S+L H R H +P C+ CG+ F + NL H H+ A Sbjct: 906 CGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERA 959 Score = 44.3 bits (103), Expect = 8e-04 Identities = 20/56 (35%), Positives = 28/56 (50%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475 ++C C + F L+ H HTGER FKC +C RF+ +L H + H P Sbjct: 876 YRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARP 931 Score = 41.2 bits (95), Expect = 0.007 Identities = 19/58 (32%), Positives = 28/58 (48%) Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQ 478 +C C K F S L H R H GER ++C CG F ++ H + H+ P ++ Sbjct: 933 RCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHEPPRPELR 990 Score = 41.2 bits (95), Expect = 0.007 Identities = 17/53 (32%), Positives = 23/53 (43%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAK 732 +C C + + H H G RPF+C CG F LK H H+A+ Sbjct: 990 RCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAE 1042 Score = 39.3 bits (90), Expect = 0.025 Identities = 19/58 (32%), Positives = 25/58 (43%) Query: 975 PSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKEL 1032 P C C K F H +H RPF C+ C G + LK+H L H+ + L Sbjct: 987 PELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAENL 1044 >gi|148276998 zinc finger protein 628 [Homo sapiens] Length = 1055 Score = 127 bits (318), Expect = 9e-29 Identities = 139/553 (25%), Positives = 188/553 (33%), Gaps = 110/553 (19%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + S+L+ H HTGERP+ C +CG++FT NL+ H VH + P R Sbjct: 143 PYPCPDCPKAFKNSSSLRRHRHVHTGERPYTCGVCGKSFTQSTNLRQHQRVHTGERPFR- 201 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTP--------------------------- 770 CP+C K FT++ L H R H P T Sbjct: 202 ---CPLCPKTFTHSSNLLLHQRTHGAAPAPGTASAAPPPQSREPGKVFVCDAYLQRHLQP 258 Query: 771 ----------------LPEGFQDAMDS--ELAYDDKNAETLSSYDDDMDENSMEDDAELK 812 +PE F A ++ EL Y E S ++ + E+ Sbjct: 259 HSPPAPPAPPPPPPPVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEH---QPCPGP 315 Query: 813 DAATDPAK-PLLSYAGSCPPSP-PSVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSG 870 DAA P + P + PPSP P AA + S + + GL ++ G Sbjct: 316 DAAPQPQEAPAEAPKADQPPSPLPQPPPPAAAPAPGFACLPCGKSFRTVAGLSRHQHSHG 375 Query: 871 ESDRLSNDSSSAVGD--------------LESRSAGSPALSESSSSQALSPAPSNGESFR 916 + + S G +E +AG P ++ P Sbjct: 376 AAGGQAFRCGSCDGSFPQLASLLAHQQCHVEEAAAGRPPPQAEAAEVTCPQEP------- 428 Query: 917 SKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPS 976 +P P P P ERP A S G +G++ L G+ P Sbjct: 429 -LAPAAPVPPPPPSAPASAERPYKCAECGKS--FKGSSGLR-------YHLRDHTGERPY 478 Query: 977 TVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQL 1036 CG CGK F S L IH R HT R F C C + + HL H Sbjct: 479 Q-CGECGKAFKRSSLLAIHQRVHTGLRAFTCGQCGLTFKWSSHYQYHLRLH--------- 528 Query: 1037 FDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP 1096 S P + + GE P GV G Sbjct: 529 ---------SGERPYACGECGKAFRNTSCLRRHRHVHTGERPH-ACGV---CGKSFAQTS 575 Query: 1097 GLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNL 1156 L P C C KTF+ +S L +H+RTH+ E+PF C ICGR F L Sbjct: 576 NLRQHQRVHTGERP--FRCPLCPKTFTHSSNLLLHQRTHSAERPFTCPICGRGFVMAAYL 633 Query: 1157 KVHMGTHMWNNAP 1169 + H+ TH N P Sbjct: 634 QRHLRTHAPANTP 646 Score = 115 bits (289), Expect = 2e-25 Identities = 122/501 (24%), Positives = 170/501 (33%), Gaps = 136/501 (27%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740 C C S + H R HTGERP+ C C +AF +L+ H VH + P ++ Sbjct: 118 CGQCGLAFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNSSSLRRHRHVHTGERP----YT 173 Query: 741 CPICQKKFTNAVVLQQHIRMHMGGQIPNTPL-PEGFQDAMDSELAYDDKNAE----TLSS 795 C +C K FT + L+QH R+H G + PL P+ F + + L A T S+ Sbjct: 174 CGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAPAPGTASA 233 Query: 796 YDDDMDENS---MEDDAELK---DAATDPAKPLLSYAGSCPPSPPSVISS--IAALENQM 847 DA L+ + PA P + PP PP V+ +AA E + Sbjct: 234 APPPQSREPGKVFVCDAYLQRHLQPHSPPAPP------APPPPPPPVVPELFLAAAETTV 287 Query: 848 KMIDSVMSCQQLTGLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSP 907 +++ C+Q SS L Sbjct: 288 ELVYRCDGCEQ--------------------------------------GFSSEELLLEH 309 Query: 908 APSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFL 967 P PG A +PQE P + + D P + P A Sbjct: 310 QP---------CPGPDAAPQPQEAPAEAPKADQPPSPLPQPPPPAAA------------- 347 Query: 968 SRERGKCPSTVCGVCGKPFACKSALEIHYRSH--TKERPFVCALCRRGCSTMGNLKQHLL 1025 P C CGK F + L H SH + F C C + +L H Sbjct: 348 -----PAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRCGSCDGSFPQLASLLAHQQ 402 Query: 1026 THRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQ 1085 H + AA G PP + Sbjct: 403 CH-------------------------VEEAA----------------AGRPPPQAEAAE 421 Query: 1086 VPAGPQTVMGPGLAPMLAPP---PRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFG 1142 V PQ + P AP+ PP P + + C CGK+F +S L+ H R HTGE+P+ Sbjct: 422 VTC-PQEPLAPA-APVPPPPPSAPASAERPYKCAECGKSFKGSSGLRYHLRDHTGERPYQ 479 Query: 1143 CTICGRAFTTKGNLKVHMGTH 1163 C CG+AF L +H H Sbjct: 480 CGECGKAFKRSSLLAIHQRVH 500 Score = 94.0 bits (232), Expect = 8e-19 Identities = 141/633 (22%), Positives = 216/633 (34%), Gaps = 145/633 (22%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH--------- 470 + C C K F + L+ H R HTGERPF+C +C F+ NL +H + H Sbjct: 172 YTCGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAPAPGTA 231 Query: 471 ------KEKYP------------HIQMNPYPVPEY--------------------LDNVP 492 + + P H+Q + P P ++ V Sbjct: 232 SAAPPPQSREPGKVFVCDAYLQRHLQPHSPPAPPAPPPPPPPVVPELFLAAAETTVELVY 291 Query: 493 TCSGIPYGMSL------------------PPEKPVTTWLDSKPVLPTVPTSVGLQLPPTV 534 C G G S P E P +P P+ + PP Sbjct: 292 RCDGCEQGFSSEELLLEHQPCPGPDAAPQPQEAPAEAPKADQP-----PSPLPQPPPPAA 346 Query: 535 PGAHGYADSPSA----TPASRSPQRPSPASS-----ECASLSPGLNHVESGVSATAESPQ 585 A G+A P T A S + S ++ C S + S ++ + Sbjct: 347 APAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRCGSCDGSFPQLASLLAHQQCHVE 406 Query: 586 SLLGGPPLTKAEPVSLPCTNAR-AGDAPVGAQASAAPTSVDG-------APTSLGSPGLP 637 G P +AE + C A APV +AP S + + GS GL Sbjct: 407 EAAAGRPPPQAEAAEVTCPQEPLAPAAPVPPPPPSAPASAERPYKCAECGKSFKGSSGLR 466 Query: 638 AVSEQFKAQFPF--GGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALK 695 + P+ G + + S + Q V + T C C S + Sbjct: 467 YHLRDHTGERPYQCGECGKAFKRSSLLAIHQRVHTGLRAFT----CGQCGLTFKWSSHYQ 522 Query: 696 MHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQ 755 H R H+GERP+ C CG+AF L+ H VH + P H+C +C K F L+ Sbjct: 523 YHLRLHSGERPYACGECGKAFRNTSCLRRHRHVHTGERP----HACGVCGKSFAQTSNLR 578 Query: 756 QHIRMHMGGQIPNTPL-PEGFQDAMDSELAYDDKNAE------------TLSSYDDDMDE 802 QH R+H G + PL P+ F + + L +AE +++Y Sbjct: 579 QHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFTCPICGRGFVMAAY------ 632 Query: 803 NSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGL 862 ++ A P AG PP+P + + A ++ V+ Q T Sbjct: 633 --LQRHLRTHAPANTPPSTTAPAAGPQPPAPLAAARAPPATQDV-----HVLPHLQATLS 685 Query: 863 KSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSPGL 922 V G+ ++ L + ++ L ++A L SS P P Sbjct: 686 LEVAGGTAQAPSLGPAAPNSQTFLLVQTAQGLQLIPSSVQPPTPPPP------------- 732 Query: 923 GAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAG 955 P P+ I L P+++ G+GG R G Sbjct: 733 --PAPPKLILL-------PSSSAGAGGGRARQG 756 Score = 86.3 bits (212), Expect = 2e-16 Identities = 79/256 (30%), Positives = 97/256 (37%), Gaps = 38/256 (14%) Query: 242 LSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGA------QPLSRP 295 L P + P+ P P P P + L L+A + F QP P Sbjct: 256 LQPHSPPAPPAPPPPPPPVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGP 315 Query: 296 ESGASTPGGPAE-PSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAP------ 348 ++ PAE P A PS P P PA APAP A +S T L+ Sbjct: 316 DAAPQPQEAPAEAPKADQPPSPLPQPPPPAAAPAPGFACLPCGKSFRTVAGLSRHQHSHG 375 Query: 349 ---------GSLLGAAPGLPSPLLPQT-----SASGVIFPNPLVSIAATANALDPLSALM 394 GS G+ P L S L Q +A+G P A A P L Sbjct: 376 AAGGQAFRCGSCDGSFPQLASLLAHQQCHVEEAAAGRPPPQ-----AEAAEVTCPQEPLA 430 Query: 395 KHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICG 454 PP S ASAE P+ KC C K F S L+ HLR HTGERP++C CG Sbjct: 431 PAAPVPPPPPSA---PASAERPY---KCAECGKSFKGSSGLRYHLRDHTGERPYQCGECG 484 Query: 455 NRFSTKGNLKVHFQRH 470 F L +H + H Sbjct: 485 KAFKRSSLLAIHQRVH 500 Score = 83.6 bits (205), Expect = 1e-15 Identities = 105/400 (26%), Positives = 145/400 (36%), Gaps = 69/400 (17%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP---- 475 + C C K F + S+L+ H HTGERP+ C +CG F+ NL+ H + H + P Sbjct: 144 YPCPDCPKAFKNSSSLRRHRHVHTGERPYTCGVCGKSFTQSTNLRQHQRVHTGERPFRCP 203 Query: 476 --------------HIQMN-PYPVPEYLDNVPTCSGIPYGMSLPPEKPVT--TWLDS--K 516 H + + P P T S P S P K +L + Sbjct: 204 LCPKTFTHSSNLLLHQRTHGAAPAP------GTASAAPPPQSREPGKVFVCDAYLQRHLQ 257 Query: 517 PVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLS----PGLNH 572 P P P + PP VP A + R SSE L PG + Sbjct: 258 PHSPPAPPAPPPPPPPVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGPDA 317 Query: 573 VESGVSATAESPQ-----SLLGGPPLTKAEP----VSLPC----------TNARAGDAPV 613 A AE+P+ S L PP A P LPC + + Sbjct: 318 APQPQEAPAEAPKADQPPSPLPQPPPPAAAPAPGFACLPCGKSFRTVAGLSRHQHSHGAA 377 Query: 614 GAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLV----- 668 G QA S DG+ L S L A + + G + +E + Q+ + Sbjct: 378 GGQAFRC-GSCDGSFPQLAS--LLAHQQCHVEEAAAGRPPPQAEAAEVTCPQEPLAPAAP 434 Query: 669 -----ENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLK 723 + P +C C + S L+ H R HTGERP++C CG+AF L Sbjct: 435 VPPPPPSAPASAERPYKCAECGKSFKGSSGLRYHLRDHTGERPYQCGECGKAFKRSSLLA 494 Query: 724 THFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 H VH LR +C C F + Q H+R+H G Sbjct: 495 IHQRVHTG---LRA-FTCGQCGLTFKWSSHYQYHLRLHSG 530 Score = 79.0 bits (193), Expect = 3e-14 Identities = 154/668 (23%), Positives = 206/668 (30%), Gaps = 167/668 (25%) Query: 47 GEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSER 106 GE C C F ++ L HQR+ H APAP P + P + Sbjct: 196 GERPFRCPLCPKTFTHSSNLLLHQRT----------HGAAPAPGTASAAPPPQSREPGKV 245 Query: 107 AESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNV 166 +A + + P PPA PAPP P P Sbjct: 246 FVCDAYLQRHLQ--------------------------PHSPPAPPAPPPPP--PPVVPE 277 Query: 167 TLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQI 226 A T V + G S E+L+ L+ Q Q Sbjct: 278 LFLAAAETTVELVYRCDGCEQGFSS---------------EELL-LEHQPCPGPDAAPQP 321 Query: 227 RSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAG-------SG 279 + A P+ P+ P P PA + PG A LP G +AG G Sbjct: 322 QEAPA----EAPKADQPPSPLPQPPPPAAAPAPGFACLP--CGKSFRTVAGLSRHQHSHG 375 Query: 280 PAAPAAFE---------------GAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPA 324 A AF Q E+ A P AE + P APAAP Sbjct: 376 AAGGQAFRCGSCDGSFPQLASLLAHQQCHVEEAAAGRPPPQAEAAEVTCPQEPLAPAAPV 435 Query: 325 PAPAPQSAASSQPQSASTPPALAP-GSLLGAAPGLPSPLLPQTSA--------------S 369 P P P S P SA P A G + GL L T S Sbjct: 436 PPPPP-----SAPASAERPYKCAECGKSFKGSSGLRYHLRDHTGERPYQCGECGKAFKRS 490 Query: 370 GVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVF 429 ++ + V A K ++ + S E P+ C C K F Sbjct: 491 SLLAIHQRVHTGLRAFTCGQCGLTFKWSSHYQYHLRLH----SGERPY---ACGECGKAF 543 Query: 430 GSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP-------------- 475 + S L+ H HTGERP C +CG F+ NL+ H + H + P Sbjct: 544 RNTSCLRRHRHVHTGERPHACGVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSS 603 Query: 476 --------HIQMNPYPVP---------EYLD---------NVPTCSGIPYGMSLPPEKPV 509 H P+ P YL N P + P PP P+ Sbjct: 604 NLLLHQRTHSAERPFTCPICGRGFVMAAYLQRHLRTHAPANTPPSTTAPAAGPQPP-APL 662 Query: 510 TTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPG 569 + P V LQ ++ A G A +PS PA+ P+ + + G Sbjct: 663 AA-ARAPPATQDVHVLPHLQATLSLEVAGGTAQAPSLGPAA-----PNSQTFLLVQTAQG 716 Query: 570 LNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPT 629 L + S V Q PP + + LP ++A AG G +A P +V A Sbjct: 717 LQLIPSSV-------QPPTPPPPPAPPKLILLPSSSAGAG----GGRARQGPRAVGKAGQ 765 Query: 630 SLGSPGLP 637 G LP Sbjct: 766 GAGVVWLP 773 Score = 76.6 bits (187), Expect = 1e-13 Identities = 62/228 (27%), Positives = 86/228 (37%), Gaps = 51/228 (22%) Query: 942 AAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTK 1001 + A G+G PG A A + CG CGK F S L H R+HT Sbjct: 12 STAEGAGEKPGPAAPAPAAQYE---------------CGECGKSFRWSSRLLHHQRTHTG 56 Query: 1002 ERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMI 1061 ERP+ C C + L H H E P Q D P ++ I Sbjct: 57 ERPYKCPDCPKAFKGSSALLYHQRGH-TGERPYQCPD----------CPKAFKRSSLLQI 105 Query: 1062 KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHN------C 1115 V+ +A G+ GLA + + +QH C Sbjct: 106 HRSVHTGLRAFICGQ-------------------CGLAFKWSSHYQYHLRQHTGERPYPC 146 Query: 1116 QSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 C K F ++S+L+ H HTGE+P+ C +CG++FT NL+ H H Sbjct: 147 PDCPKAFKNSSSLRRHRHVHTGERPYTCGVCGKSFTQSTNLRQHQRVH 194 Score = 73.9 bits (180), Expect = 9e-13 Identities = 68/249 (27%), Positives = 87/249 (34%), Gaps = 53/249 (21%) Query: 972 GKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKE 1031 G+ P T CGVCGK F + L H R HT ERPF C LC + + NL H TH Sbjct: 168 GERPYT-CGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAP 226 Query: 1032 LPS--------QLFDPNFAL-----------------------GPSQSTPSLISSAAPTM 1060 P Q +P P P L +AA T Sbjct: 227 APGTASAAPPPQSREPGKVFVCDAYLQRHLQPHSPPAPPAPPPPPPPVVPELFLAAAETT 286 Query: 1061 IKMEVN------GHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQ-- 1112 +++ G L E P P A PQ P AP PP P+ Sbjct: 287 VELVYRCDGCEQGFSSEELLLEHQPCPGP---DAAPQPQEAPAEAPKADQPPSPLPQPPP 343 Query: 1113 --------HNCQSCGKTFSSASALQIHERTH--TGEKPFGCTICGRAFTTKGNLKVHMGT 1162 C CGK+F + + L H+ +H G + F C C +F +L H Sbjct: 344 PAAAPAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRCGSCDGSFPQLASLLAHQQC 403 Query: 1163 HMWNNAPAR 1171 H+ A R Sbjct: 404 HVEEAAAGR 412 Score = 61.2 bits (147), Expect = 6e-09 Identities = 54/178 (30%), Positives = 65/178 (36%), Gaps = 49/178 (27%) Query: 979 CGVCGK-------------------PFAC---------KSALEIHYRSHTKERPFVCALC 1010 CGVCGK PF C S L +H R+H+ ERPF C +C Sbjct: 564 CGVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFTCPIC 623 Query: 1011 RRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAP------------ 1058 RG L++HL TH P P A GP P + A P Sbjct: 624 GRGFVMAAYLQRHLRTHAPANTPPSTTAP--AAGPQPPAPLAAARAPPATQDVHVLPHLQ 681 Query: 1059 TMIKMEVNGHGKAMALGEGPPLPAG-----VQVPAGPQTVMGPGLAPMLAPPPRRTPK 1111 + +EV G G A A GP P VQ G Q + + P PPP PK Sbjct: 682 ATLSLEVAG-GTAQAPSLGPAAPNSQTFLLVQTAQGLQLIPS-SVQPPTPPPPPAPPK 737 Score = 55.1 bits (131), Expect = 4e-07 Identities = 30/76 (39%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 1088 AGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICG 1147 A T G G P A P Q+ C CGK+F +S L H+RTHTGE+P+ C C Sbjct: 9 APASTAEGAGEKPGPAAPAPAA--QYECGECGKSFRWSSRLLHHQRTHTGERPYKCPDCP 66 Query: 1148 RAFTTKGNLKVHMGTH 1163 +AF L H H Sbjct: 67 KAFKGSSALLYHQRGH 82 Score = 50.4 bits (119), Expect = 1e-05 Identities = 25/69 (36%), Positives = 35/69 (50%) Query: 408 EPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHF 467 +P +A P +++C C K F S L H R+HTGERP+KC C F L H Sbjct: 20 KPGPAAPAPAAQYECGECGKSFRWSSRLLHHQRTHTGERPYKCPDCPKAFKGSSALLYHQ 79 Query: 468 QRHKEKYPH 476 + H + P+ Sbjct: 80 RGHTGERPY 88 Score = 50.1 bits (118), Expect = 1e-05 Identities = 22/51 (43%), Positives = 27/51 (52%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 +KC C K F SAL H R HTGERP++C C F L++H H Sbjct: 60 YKCPDCPKAFKGSSALLYHQRGHTGERPYQCPDCPKAFKRSSLLQIHRSVH 110 Score = 50.1 bits (118), Expect = 1e-05 Identities = 31/96 (32%), Positives = 43/96 (44%), Gaps = 20/96 (20%) Query: 391 SALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKC 450 SAL+ H++G + E P+ +C C K F S LQIH HTG R F C Sbjct: 73 SALLYHQRGH-----------TGERPY---QCPDCPKAFKRSSLLQIHRSVHTGLRAFIC 118 Query: 451 NICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPE 486 CG F + + H ++H + PYP P+ Sbjct: 119 GQCGLAFKWSSHYQYHLRQHTGE------RPYPCPD 148 Score = 47.8 bits (112), Expect = 7e-05 Identities = 73/286 (25%), Positives = 100/286 (34%), Gaps = 58/286 (20%) Query: 28 AAPGEGAEDADSGPESRSGGEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAP 87 AAP G A P+SR G+ VC+ Q PP P Sbjct: 224 AAPAPGTASAAPPPQSREPGK-VFVCDAYLQRHL--------QPHSPPAPPA------PP 268 Query: 88 APPPEDFPEPSPASSPSERAESEAAEEAGAEGAEGEARPVEKE------AEPMDAE-PAG 140 PPP PE A++ + E + +G E +E + A P E PA Sbjct: 269 PPPPPVVPELFLAAAETT-VELVYRCDGCEQGFSSEELLLEHQPCPGPDAAPQPQEAPAE 327 Query: 141 DTRAPRPPPAAPAPPTPAYGAPSTN---VTLEALLSTKVAVAQFSQGARAAGGSGAGGGV 197 +A +PP P PP PA AP+ + T +++ AAGG G Sbjct: 328 APKADQPPSPLPQPPPPA-AAPAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRCGS 386 Query: 198 AAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQ 257 + P L L+A QQ + + A RPPP+ + P P Sbjct: 387 CDGSFPQ-LASLLAHQQCHVEE-----------AAAGRPPPQAEAAEVTCPQEP------ 428 Query: 258 LPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPG 303 APAA + P+APA+ E +P E G S G Sbjct: 429 -----------LAPAAPVPPPPPSAPASAE--RPYKCAECGKSFKG 461 Score = 45.8 bits (107), Expect = 3e-04 Identities = 21/55 (38%), Positives = 26/55 (47%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 C C F S Q HLR HTGERP+ C C F +L+ H H + P+ Sbjct: 118 CGQCGLAFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNSSSLRRHRHVHTGERPY 172 Score = 44.7 bits (104), Expect = 6e-04 Identities = 53/260 (20%), Positives = 80/260 (30%), Gaps = 76/260 (29%) Query: 978 VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKE-----L 1032 +CG CG F S + H R HT ERP+ C C + +L++H H + + Sbjct: 117 ICGQCGLAFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNSSSLRRHRHVHTGERPYTCGV 176 Query: 1033 PSQLFDPNFALGPSQST------------PSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080 + F + L Q P + ++ ++ +G A P Sbjct: 177 CGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAPAPGTASAAPP 236 Query: 1081 P------------AGVQVPAGPQTVMGPGLAPMLAPPPRRTPK------------QHNCQ 1116 P A +Q P + P P PPP P+ + C Sbjct: 237 PQSREPGKVFVCDAYLQRHLQPHSPPAPPAPP--PPPPPVVPELFLAAAETTVELVYRCD 294 Query: 1117 SCGKTFSSASALQIHE-----------RTHTGEKP----------------------FGC 1143 C + FSS L H+ + E P F C Sbjct: 295 GCEQGFSSEELLLEHQPCPGPDAAPQPQEAPAEAPKADQPPSPLPQPPPPAAAPAPGFAC 354 Query: 1144 TICGRAFTTKGNLKVHMGTH 1163 CG++F T L H +H Sbjct: 355 LPCGKSFRTVAGLSRHQHSH 374 Score = 41.2 bits (95), Expect = 0.007 Identities = 29/92 (31%), Positives = 34/92 (36%) Query: 936 ERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIH 995 E+P A AP + G G LL R C C K F SAL H Sbjct: 19 EKPGPAAPAPAAQYECGECGKSFRWSSRLLHHQRTHTGERPYKCPDCPKAFKGSSALLYH 78 Query: 996 YRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 R HT ERP+ C C + L+ H H Sbjct: 79 QRGHTGERPYQCPDCPKAFKRSSLLQIHRSVH 110 Score = 40.4 bits (93), Expect = 0.011 Identities = 77/307 (25%), Positives = 99/307 (32%), Gaps = 61/307 (19%) Query: 883 VGDLESRSAGSPALSESSSSQALSPAPSN-------GESFRSKSPGLGAPE-EPQEIPLK 934 VG + S A +PAP+ G+SFR S L E P K Sbjct: 2 VGSHADMAPASTAEGAGEKPGPAAPAPAAQYECGECGKSFRWSSRLLHHQRTHTGERPYK 61 Query: 935 TERPDSPAAAPGSGGAP-GRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALE 993 PD P A GS + G E P+ +CP C K F S L+ Sbjct: 62 C--PDCPKAFKGSSALLYHQRGHTGERPY----------QCPD-----CPKAFKRSSLLQ 104 Query: 994 IHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLI 1053 IH HT R F+C C + + HL H E P P P Sbjct: 105 IHRSVHTGLRAFICGQCGLAFKWSSHYQYHLRQH-TGERPY----------PCPDCPKAF 153 Query: 1054 SSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQH 1113 +++ V+ GE P GV G L P Sbjct: 154 KNSSSLRRHRHVH-------TGE-RPYTCGV---CGKSFTQSTNLRQHQRVHTGERP--F 200 Query: 1114 NCQSCGKTFSSASALQIHERTHTGEKPFGCTIC----------GRAFTTKGNLKVHMGTH 1163 C C KTF+ +S L +H+RTH G P T G+ F L+ H+ H Sbjct: 201 RCPLCPKTFTHSSNLLLHQRTH-GAAPAPGTASAAPPPQSREPGKVFVCDAYLQRHLQPH 259 Query: 1164 MWNNAPA 1170 PA Sbjct: 260 SPPAPPA 266 Score = 32.0 bits (71), Expect = 4.0 Identities = 63/284 (22%), Positives = 90/284 (31%), Gaps = 37/284 (13%) Query: 138 PAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGV 197 PA + P A P PP P A + T + + + Q + AGG+ + Sbjct: 642 PANTPPSTTAPAAGPQPPAPLAAARAPPATQDVHVLPHL---QATLSLEVAGGTAQAPSL 698 Query: 198 AAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQ 257 AA L Q LQLI S+ P P P P Sbjct: 699 GPAAP----NSQTFLLVQTAQGLQLIPS---------------SVQPPTPPPPPAP---- 735 Query: 258 LPGLAALPLSAGAPAAAIAGSGP-AAPAAFEGAQPLSRP-ESGASTPGGPAEPSAPAAPS 315 P L LP S+ A GP A A +GA + P G G + ++ S Sbjct: 736 -PKLILLPSSSAGAGGGRARQGPRAVGKAGQGAGVVWLPGPGGLGVQGAASAGASGTGQS 794 Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375 PQ + Q Q P + L A L P + V Sbjct: 795 LIVLQNVGGGEAGPQEMSGVQLQPLRPAPEVTTVQLQPAQEVTTVQLQPAQEVTTVQL-Q 853 Query: 376 PLVSIAATANALDPLSALMKHRKG-----KPPNVSVFEPKASAE 414 P + T L P++ + + G + PN+ V + A+ E Sbjct: 854 PAQEV--TTVQLQPVAGQLSNSSGGAVATEAPNLLVVQSGAAEE 895 Score = 31.6 bits (70), Expect = 5.2 Identities = 68/270 (25%), Positives = 88/270 (32%), Gaps = 35/270 (12%) Query: 133 PMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAAGGSG 192 P PA + P P AA AP PA L+A LS +V AGG+ Sbjct: 647 PSTTAPAAGPQPPAPLAAARAP--PATQDVHVLPHLQATLSLEV-----------AGGTA 693 Query: 193 AGGGVAAAAVPLILEQLMALQQQQIHQLQLI-EQIRSQVALMQRPPPRPSLSPAAAPSAP 251 + AA L Q LQLI ++ PP+ L P+++ A Sbjct: 694 QAPSLGPAAP----NSQTFLLVQTAQGLQLIPSSVQPPTPPPPPAPPKLILLPSSSAGAG 749 Query: 252 GPAPSQLPGLAALPLSAGAPAAAIAGSGP-------AAPAAFEG-AQPLSRPESGASTPG 303 G Q P AG A + GP AA A G Q L ++ Sbjct: 750 GGRARQGPRAVG---KAGQGAGVVWLPGPGGLGVQGAASAGASGTGQSLIVLQNVGGGEA 806 Query: 304 GPAEPSAPAAPSAAPAPAAPAPAPAPQSAASS---QPQSASTPPALAPGSLLGAAPGLPS 360 GP E S PAP P ++ QP T L P + P Sbjct: 807 GPQEMSGVQLQPLRPAPEVTTVQLQPAQEVTTVQLQPAQEVTTVQLQPAQEVTTVQLQPV 866 Query: 361 PLLPQTSASGVI---FPNPLVSIAATANAL 387 S+ G + PN LV + A L Sbjct: 867 AGQLSNSSGGAVATEAPNLLVVQSGAAEEL 896 >gi|69885084 p120E4F [Homo sapiens] Length = 784 Score = 111 bits (278), Expect = 4e-24 Identities = 114/483 (23%), Positives = 171/483 (35%), Gaps = 81/483 (16%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740 C +CH+ S LK H TH+ + +CK+CG +F TKG+L H H + P + Sbjct: 194 CALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERP----YK 249 Query: 741 CPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSELAYDDKNAETLSSYDDDM 800 C C K F + L +H++ TP E + ++ ++ ++A S Sbjct: 250 CSKCGKSFRESGALTRHLKSL-------TPCTEKIRFSVSKDVVVSKEDARA-GSGAGAA 301 Query: 801 DENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLT 860 + + T P L++ A +VI + ++ + ++ + Sbjct: 302 GLGTATSSVTGEPIETSPVIHLVTDAKG------TVIHEVHVQMQELSLGMKALAPEPPV 355 Query: 861 GLKSVENGSGESDRLSNDSSSAVGDLESRSAGSPALSESSSSQALSPAPSNGESFRSKSP 920 + + G + L + + G + R+AG AL PAP+ G S Sbjct: 356 SQELPCSSEGSRENLLHQAMQNSGIVLERAAGEEG--------ALEPAPAAGSS------ 401 Query: 921 GLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCG 980 PQ PL P P + E P S + C Sbjct: 402 -------PQ--PLAVAAPQLP--------------VLEVQPLETQVASEASAVPRTHPCP 438 Query: 981 VCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPN 1040 C + F + LE H R HT RPF CA C + LK+H H + + Sbjct: 439 QCSETFPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLLKKHQEVH--------VRERR 490 Query: 1041 FALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLP-AGVQVPAGPQTVMGPGLA 1099 F G I+ V GH + + P P G + A Sbjct: 491 FRCGDCGKLYKTIA---------HVRGHRRVHSDERPYPCPKCGKRYKTKN--------A 533 Query: 1100 PMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVH 1159 + K H CQ C + F +L H R HTGEKPF C CGR F G L H Sbjct: 534 QQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRH 593 Query: 1160 MGT 1162 + T Sbjct: 594 LRT 596 Score = 86.3 bits (212), Expect = 2e-16 Identities = 114/505 (22%), Positives = 177/505 (35%), Gaps = 70/505 (13%) Query: 305 PAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGS-------------- 350 PA P+ A PAAP P P + A ++AS ++ S Sbjct: 91 PATPATTALLGQEVVPAAPGPEE-PITVAHIVVEAASLAADISHASDLVGGGHIKEVIVA 149 Query: 351 ---LLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVF 407 LG +P P+ G+ + N + H+ K S+ Sbjct: 150 AEAELGDGEMAEAPGSPRQQGLGLAGEGEQAQVKLLVNKDGRYVCALCHKTFKTG--SIL 207 Query: 408 EPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHF 467 + H+C+ C F + +L H R HT ERP+KC+ CG F G L H Sbjct: 208 KAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRHTDERPYKCSKCGKSFRESGALTRHL 267 Query: 468 QRHKEKYPHIQMNPYPVPEYL----DNVPTCSGI-PYGMSLPPEKPVTTWLDSKPVL--- 519 K P + + V + + ++ SG G+ +++ PV+ Sbjct: 268 ---KSLTPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTATSSVTGEPIETSPVIHLV 324 Query: 520 ----PTVPTSVGLQLPPTVPGAHGYADSPSAT---PASRSPQRPSPASSECASLSPGLNH 572 TV V +Q+ G A P + P S R + + L Sbjct: 325 TDAKGTVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSRENLLHQAMQNSGIVLER 384 Query: 573 VESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTS------VDG 626 A +P + PL A P LP + + V ++ASA P + + Sbjct: 385 AAGEEGALEPAPAAGSSPQPLAVAAP-QLPVLEVQPLETQVASEASAVPRTHPCPQCSET 443 Query: 627 APTSL-------GSPG-LPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDP 678 PT+ G G P Q FP LL K Q V +++ Sbjct: 444 FPTAATLEAHKRGHTGPRPFACAQCGKAFPKAYLL---------KKHQEVHVRERRF--- 491 Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738 +C C ++ + ++ H R H+ ERP+ C CG+ + TK + HF H + P Sbjct: 492 -RCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHLEEKP---- 546 Query: 739 HSCPICQKKFTNAVVLQQHIRMHMG 763 H C C + F L +H+R H G Sbjct: 547 HVCQFCSRGFREKGSLVRHVRHHTG 571 Score = 65.5 bits (158), Expect = 3e-10 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 1/86 (1%) Query: 1079 PLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGE 1138 P P V P P + P L +A P+ H C C +TF +A+ L+ H+R HTG Sbjct: 402 PQPLAVAAPQLPVLEVQP-LETQVASEASAVPRTHPCPQCSETFPTAATLEAHKRGHTGP 460 Query: 1139 KPFGCTICGRAFTTKGNLKVHMGTHM 1164 +PF C CG+AF LK H H+ Sbjct: 461 RPFACAQCGKAFPKAYLLKKHQEVHV 486 Score = 65.1 bits (157), Expect = 4e-10 Identities = 79/323 (24%), Positives = 124/323 (38%), Gaps = 54/323 (16%) Query: 164 TNVTLEALLSTKVAVAQFSQGARAAGGSGAGG-GVAAAAV---PL----ILEQLMALQQQ 215 T T + S V + ARA G+GA G G A ++V P+ ++ + + Sbjct: 271 TPCTEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGT 330 Query: 216 QIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAI 275 IH++ + Q++ M+ P P +S S+ G + L AA Sbjct: 331 VIHEVHV--QMQELSLGMKALAPEPPVSQELPCSSEGSRENLLHQAMQNSGIVLERAAGE 388 Query: 276 AGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPS-AAPAPAAPAPAPAPQSAAS 334 G+ APAA QPL+ + P P P A+ A A P P PQ + + Sbjct: 389 EGALEPAPAAGSSPQPLA-----VAAPQLPVLEVQPLETQVASEASAVPRTHPCPQCSET 443 Query: 335 SQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALM 394 P+ + G P P + A A L Sbjct: 444 -----------------------FPTAATLEAHKRGHTGPRPF-ACAQCGKAFPKAYLLK 479 Query: 395 KHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICG 454 KH++ V V E + +C C K++ + + ++ H R H+ ERP+ C CG Sbjct: 480 KHQE-----VHVRERR---------FRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCG 525 Query: 455 NRFSTKGNLKVHFQRHKEKYPHI 477 R+ TK +VHF+ H E+ PH+ Sbjct: 526 KRYKTKNAQQVHFRTHLEEKPHV 548 Score = 53.9 bits (128), Expect = 1e-06 Identities = 46/187 (24%), Positives = 76/187 (40%), Gaps = 21/187 (11%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPA 1170 K H C+ CG +F + +L H R HT E+P+ C+ CG++F G L H+ + P Sbjct: 218 KDHECKLCGASFRTKGSLIRHHRRHTDERPYKCSKCGKSFRESGALT----RHLKSLTPC 273 Query: 1171 RRGRRLSVENPMALLGGDALKFSEMFQKDLAARAMNV--DPSFWNQYAAAITNGLAMKNN 1228 R SV + + DA S L +V +P + +T+ Sbjct: 274 TEKIRFSVSKDVVVSKEDARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKG---- 329 Query: 1229 EISVIQNGGIPQLPVSLGGSALPPLGSMASGMDKARTGSSPPI---------VSLDKASS 1279 +VI + +SLG AL P ++ + + GS + + L++A+ Sbjct: 330 --TVIHEVHVQMQELSLGMKALAPEPPVSQELPCSSEGSRENLLHQAMQNSGIVLERAAG 387 Query: 1280 ETAASRP 1286 E A P Sbjct: 388 EEGALEP 394 Score = 52.8 bits (125), Expect = 2e-06 Identities = 22/53 (41%), Positives = 30/53 (56%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 + + C CGK + + +A Q+H RTH EKP C C R F KG+L H+ H Sbjct: 517 RPYPCPKCGKRYKTKNAQQVHFRTHLEEKPHVCQFCSRGFREKGSLVRHVRHH 569 Score = 50.8 bits (120), Expect = 8e-06 Identities = 22/48 (45%), Positives = 26/48 (54%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTH 725 P+ C C R + +L H R HTGE+PFKC CGR F G L H Sbjct: 546 PHVCQFCSRGFREKGSLVRHVRHHTGEKPFKCYKCGRGFAEHGTLNRH 593 Score = 50.4 bits (119), Expect = 1e-05 Identities = 18/54 (33%), Positives = 32/54 (59%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHM 1164 ++ C CGK + + + ++ H R H+ E+P+ C CG+ + TK +VH TH+ Sbjct: 489 RRFRCGDCGKLYKTIAHVRGHRRVHSDERPYPCPKCGKRYKTKNAQQVHFRTHL 542 Score = 48.5 bits (114), Expect = 4e-05 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 4/117 (3%) Query: 1048 STPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPR 1107 S+P ++ AAP + +EV +A E +P P +T P A + A Sbjct: 400 SSPQPLAVAAPQLPVLEVQPLETQVA-SEASAVPRTHPCPQCSETF--PTAATLEAHKRG 456 Query: 1108 RT-PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 T P+ C CGK F A L+ H+ H E+ F C CG+ + T +++ H H Sbjct: 457 HTGPRPFACAQCGKAFPKAYLLKKHQEVHVRERRFRCGDCGKLYKTIAHVRGHRRVH 513 Score = 47.4 bits (111), Expect = 9e-05 Identities = 21/49 (42%), Positives = 27/49 (55%) Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 C C KTF + S L+ H TH+ K C +CG +F TKG+L H H Sbjct: 194 CALCHKTFKTGSILKAHMVTHSSRKDHECKLCGASFRTKGSLIRHHRRH 242 Score = 41.2 bits (95), Expect = 0.007 Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 7/88 (7%) Query: 942 AAAPGSGGAPGR--AGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSH 999 A APGS G AG E+A LL K VC +C K F S L+ H +H Sbjct: 160 AEAPGSPRQQGLGLAGEGEQAQVKLLV-----NKDGRYVCALCHKTFKTGSILKAHMVTH 214 Query: 1000 TKERPFVCALCRRGCSTMGNLKQHLLTH 1027 + + C LC T G+L +H H Sbjct: 215 SSRKDHECKLCGASFRTKGSLIRHHRRH 242 Score = 37.4 bits (85), Expect = 0.094 Identities = 45/146 (30%), Positives = 58/146 (39%), Gaps = 26/146 (17%) Query: 24 APEHAAPGEGAEDADSG------PESRSGGEETSVCEKCCAEFFKWADFLEH--QRSCTK 75 A E A A A SG P S ++ C +C AEF DF++H Q++C + Sbjct: 25 AGEGAVAAVAAALAPSGFLGLPAPFSEEDEDDVHRCGRCQAEFTALEDFVQHKIQKACQR 84 Query: 76 LPP----------VLIVHEDAPAPP-PEDFPEPSPASSPSERAESEAAEEAGAEGAEGEA 124 PP L+ E PA P PE EP + A S AA+ + A G Sbjct: 85 APPEALPATPATTALLGQEVVPAAPGPE---EPITVAHIVVEAASLAADISHASDLVGGG 141 Query: 125 R----PVEKEAEPMDAEPAGDTRAPR 146 V EAE D E A +PR Sbjct: 142 HIKEVIVAAEAELGDGEMAEAPGSPR 167 >gi|22749325 zinc finger protein 48 [Homo sapiens] Length = 618 Score = 106 bits (265), Expect = 1e-22 Identities = 139/545 (25%), Positives = 189/545 (34%), Gaps = 125/545 (22%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG----NLKTHFG--VHRAKPP 734 C C + S L H RTHTGE+P+KC +CG+ F + +TH G +RA+PP Sbjct: 114 CGECGKSFRQMSDLVKHQRTHTGEKPYKCGVCGKGFGDSSARIKHQRTHSGEKPYRARPP 173 Query: 735 L----RVQHS----------CPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMD 780 ++ S C C K F + L +H R H G P G Sbjct: 174 AQGPPKIPRSRIPAGERPTICGECGKSFRLSSDLVKHQRTHTG----EKPYKCGICGKGF 229 Query: 781 SELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSPPSVISSI 840 + + K+ T + AAT K C + S Sbjct: 230 GDSSARIKHQRTHRGEQPPRPVVPRRQPSRAATAATQGPK-AQDKPYICTDCGKRFVLSC 288 Query: 841 AALENQMKMI------------------DSVMSCQQLTGLKSV---ENGSGESDRLSNDS 879 + L +Q + D V + TG K E G G +D S Sbjct: 289 SLLSHQRSHLGPKPFGCDVCGKEFARGSDLVKHLRVHTGEKPYLCPECGKGFAD-----S 343 Query: 880 SSAVGDLESRSAGSP-ALSE-----SSSSQALSPAPSNGESFRSKSPGLGAP---EEPQE 930 S+ V L + S P A E S SS L ++ E PG P P Sbjct: 344 SARVKHLRTHSGERPHACPECDRTFSLSSTLLRHRLTHMEPQDFSFPGYPLPALIPSPPP 403 Query: 931 IPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTV-------CGVCG 983 PL T P +P + SG G G++ E + G+ P + C CG Sbjct: 404 PPLGTSPPLTPRSPSHSGEPFGLPGLEPEPG------GPQAGEPPPPLAGDKPHKCPECG 457 Query: 984 KPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKEL----PSQLFDP 1039 K F S L H+R HT E+P++C C +G + +HL THR + PS L P Sbjct: 458 KGFRRSSDLVKHHRVHTGEKPYLCPECGKGFADSSARVKHLRTHRGERARPPPPSTLLRP 517 Query: 1040 NFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLA 1099 + GP VP P+ Sbjct: 518 HNPPGP----------------------------------------VPMAPR-------- 529 Query: 1100 PMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVH 1159 P + P + H C CGK F +S L H RTHTGEKP+ C CG+ F H Sbjct: 530 PRVRAQPSGPSQPHVCGFCGKEFPRSSDLVKHRRTHTGEKPYKCAECGKGFGDSSARIKH 589 Query: 1160 MGTHM 1164 H+ Sbjct: 590 QRGHL 594 Score = 99.8 bits (247), Expect = 2e-20 Identities = 73/215 (33%), Positives = 85/215 (39%), Gaps = 38/215 (17%) Query: 978 VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037 +C CGK FA SA H R+H+ ERP C C R S L +H LTH Sbjct: 332 LCPECGKGFADSSARVKHLRTHSGERPHACPECDRTFSLSSTLLRHRLTH---------M 382 Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097 +P P P+LI S P LG PPL +G + PG Sbjct: 383 EPQDFSFPGYPLPALIPSPPPP-------------PLGTSPPLTPRSPSHSGEPFGL-PG 428 Query: 1098 LAPMLA-------PPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAF 1150 L P PPP K H C CGK F +S L H R HTGEKP+ C CG+ F Sbjct: 429 LEPEPGGPQAGEPPPPLAGDKPHKCPECGKGFRRSSDLVKHHRVHTGEKPYLCPECGKGF 488 Query: 1151 TTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALL 1185 H+ TH RG R P LL Sbjct: 489 ADSSARVKHLRTH--------RGERARPPPPSTLL 515 Score = 93.6 bits (231), Expect = 1e-18 Identities = 131/520 (25%), Positives = 183/520 (35%), Gaps = 113/520 (21%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFK------------------------CKICG 713 P +C +C + SA H RTH+GE+P++ C CG Sbjct: 139 PYKCGVCGKGFGDSSARIKHQRTHSGEKPYRARPPAQGPPKIPRSRIPAGERPTICGECG 198 Query: 714 RAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPE 773 ++F +L H H + P + C IC K F ++ +H R H G Q P +P Sbjct: 199 KSFRLSSDLVKHQRTHTGEKP----YKCGICGKGFGDSSARIKHQRTHRGEQPPRPVVPR 254 Query: 774 GFQDAMDSELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDPAKPLLSYAGSCPPSP 833 Q + + A A+ D + + + L S+ G Sbjct: 255 R-QPSRAATAATQGPKAQDKPYICTDCGKRFVLSCSLLSHQR--------SHLG------ 299 Query: 834 PSVISSIAALENQMKMIDSVMSCQQLTGLKSV---ENGSGESDRLSNDSSSAVGDLESRS 890 P + + D V + TG K E G G +D SS+ V L + S Sbjct: 300 PKPFGCDVCGKEFARGSDLVKHLRVHTGEKPYLCPECGKGFAD-----SSARVKHLRTHS 354 Query: 891 AGSP-ALSE-----SSSSQALSPAPSNGESFRSKSPGLGAPE---EPQEIPLKTERPDSP 941 P A E S SS L ++ E PG P P PL T P +P Sbjct: 355 GERPHACPECDRTFSLSSTLLRHRLTHMEPQDFSFPGYPLPALIPSPPPPPLGTSPPLTP 414 Query: 942 AAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTV-------CGVCGKPFACKSALEI 994 + SG G G++ E + G+ P + C CGK F S L Sbjct: 415 RSPSHSGEPFGLPGLEPEPG------GPQAGEPPPPLAGDKPHKCPECGKGFRRSSDLVK 468 Query: 995 HYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKEL----PSQLFDPNFALGPSQSTP 1050 H+R HT E+P++C C +G + +HL THR + PS L P+ GP P Sbjct: 469 HHRVHTGEKPYLCPECGKGFADSSARVKHLRTHRGERARPPPPSTLLRPHNPPGPVPMAP 528 Query: 1051 SLISSAAPTMIKMEVNGHGKAMALGEGPPLP-----AGVQVPAGPQTVMGPGLAPMLAPP 1105 A P+ GP P G + P V Sbjct: 529 RPRVRAQPS-----------------GPSQPHVCGFCGKEFPRSSDLVKH---------- 561 Query: 1106 PRRT---PKQHNCQSCGKTFSSASALQIHERTHTGEKPFG 1142 RRT K + C CGK F +SA H+R H PFG Sbjct: 562 -RRTHTGEKPYKCAECGKGFGDSSARIKHQRGHLVLTPFG 600 Score = 80.9 bits (198), Expect = 7e-15 Identities = 56/194 (28%), Positives = 75/194 (38%), Gaps = 56/194 (28%) Query: 976 STVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQ 1035 + VCG CGK F S L H R+HT E+P+ C +C +G +H TH ++ Sbjct: 111 AAVCGECGKSFRQMSDLVKHQRTHTGEKPYKCGVCGKGFGDSSARIKHQRTHSGEK---- 166 Query: 1036 LFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095 P A P+Q GPP ++PAG + + Sbjct: 167 ---PYRARPPAQ-----------------------------GPPKIPRSRIPAGERPTI- 193 Query: 1096 PGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGN 1155 C CGK+F +S L H+RTHTGEKP+ C ICG+ F Sbjct: 194 -------------------CGECGKSFRLSSDLVKHQRTHTGEKPYKCGICGKGFGDSSA 234 Query: 1156 LKVHMGTHMWNNAP 1169 H TH P Sbjct: 235 RIKHQRTHRGEQPP 248 Score = 73.6 bits (179), Expect = 1e-12 Identities = 97/408 (23%), Positives = 135/408 (33%), Gaps = 100/408 (24%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481 C C K F S L H R+HTGE+P+KC ICG F H + H+ + P + P Sbjct: 194 CGECGKSFRLSSDLVKHQRTHTGEKPYKCGICGKGFGDSSARIKHQRTHRGEQPPRPVVP 253 Query: 482 YPVPEYLDNVPT----------------------CSGIPYGMSLPPEKPV------TTWL 513 P T CS + + S KP + Sbjct: 254 RRQPSRAATAATQGPKAQDKPYICTDCGKRFVLSCSLLSHQRSHLGPKPFGCDVCGKEFA 313 Query: 514 DSKPVLPTVPTSVGLQLPPTVPG-AHGYADSPSATPASRSPQRPSPASSECASLSPGLNH 572 ++ + G + P P G+ADS + R+ P + + L+ Sbjct: 314 RGSDLVKHLRVHTG-EKPYLCPECGKGFADSSARVKHLRTHSGERPHACPECDRTFSLSS 372 Query: 573 VESGVSATAESPQSL-LGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSL 631 T PQ G PL P P P+G P S + Sbjct: 373 TLLRHRLTHMEPQDFSFPGYPLPALIPSPPP--------PPLGTSPPLTPRSPSHSGEPF 424 Query: 632 GSPGL---PAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVL 688 G PGL P + + P G DK P++C C + Sbjct: 425 GLPGLEPEPGGPQAGEPPPPLAG--------------------DK----PHKCPECGKGF 460 Query: 689 SCQSALKMHYRTHTGERPFKCKICGRAFTTKG----NLKTHFGVHRAKPP---------- 734 S L H+R HTGE+P+ C CG+ F +L+TH G RA+PP Sbjct: 461 RRSSDLVKHHRVHTGEKPYLCPECGKGFADSSARVKHLRTHRG-ERARPPPPSTLLRPHN 519 Query: 735 ------------LRVQ-------HSCPICQKKFTNAVVLQQHIRMHMG 763 +R Q H C C K+F + L +H R H G Sbjct: 520 PPGPVPMAPRPRVRAQPSGPSQPHVCGFCGKEFPRSSDLVKHRRTHTG 567 Score = 65.5 bits (158), Expect = 3e-10 Identities = 83/307 (27%), Positives = 107/307 (34%), Gaps = 43/307 (14%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481 C C K F S L HLR HTGE+P+ C CG F+ H + H + PH Sbjct: 305 CDVCGKEFARGSDLVKHLRVHTGEKPYLCPECGKGFADSSARVKHLRTHSGERPH----- 359 Query: 482 YPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYA 541 PE D + S L +P P+ +P+ PP P Sbjct: 360 -ACPE-CDRTFSLSSTLLRHRLTHMEPQDFSFPGYPLPALIPS------PPPPP----LG 407 Query: 542 DSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSL 601 SP TP RSP S E L PGL G PQ+ PPL +P Sbjct: 408 TSPPLTP--RSPSH----SGEPFGL-PGLEPEPGG-------PQAGEPPPPLAGDKPHKC 453 Query: 602 P-CTNA--RAGD------APVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGL 652 P C R+ D G + P G S +A+ P Sbjct: 454 PECGKGFRRSSDLVKHHRVHTGEKPYLCPECGKGFADSSARVKHLRTHRGERARPPPPST 513 Query: 653 LDSMQTSETSKLQQLVENIDKKMTDPNQ---CVICHRVLSCQSALKMHYRTHTGERPFKC 709 L + + + P+Q C C + S L H RTHTGE+P+KC Sbjct: 514 LLRPHNPPGPVPMAPRPRVRAQPSGPSQPHVCGFCGKEFPRSSDLVKHRRTHTGEKPYKC 573 Query: 710 KICGRAF 716 CG+ F Sbjct: 574 AECGKGF 580 Score = 62.0 bits (149), Expect = 4e-09 Identities = 76/310 (24%), Positives = 104/310 (33%), Gaps = 44/310 (14%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481 C C K F S L H R+HTGE+P+KC +CG F H + H + P+ P Sbjct: 114 CGECGKSFRQMSDLVKHQRTHTGEKPYKCGVCGKGFGDSSARIKHQRTHSGEKPYRARPP 173 Query: 482 YPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYA 541 P + S IP G PT+ G G + Sbjct: 174 AQGPPKIPR----SRIPAGER-----------------------------PTICGECGKS 200 Query: 542 DSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSL 601 S+ +C G SA + ++ G P P Sbjct: 201 FRLSSDLVKHQRTHTGEKPYKCGICGKGF----GDSSARIKHQRTHRGEQPPRPVVPRRQ 256 Query: 602 PCTNARAGDAPVGAQASAAP-TSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSE 660 P A A A G +A P D + S L + PFG + + + Sbjct: 257 PSRAATA--ATQGPKAQDKPYICTDCGKRFVLSCSLLSHQRSHLGPKPFGCDVCGKEFAR 314 Query: 661 TSKL-QQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTK 719 S L + L + +K P C C + + SA H RTH+GERP C C R F+ Sbjct: 315 GSDLVKHLRVHTGEK---PYLCPECGKGFADSSARVKHLRTHSGERPHACPECDRTFSLS 371 Query: 720 GNLKTHFGVH 729 L H H Sbjct: 372 STLLRHRLTH 381 Score = 58.2 bits (139), Expect = 5e-08 Identities = 59/246 (23%), Positives = 79/246 (32%), Gaps = 42/246 (17%) Query: 249 SAPG-PAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAE 307 S PG P P+ +P PL P + S P G +P E Sbjct: 388 SFPGYPLPALIPSPPPPPLGTSPPLTPRSPSHSGEPFGLPGLEP---------------E 432 Query: 308 PSAPAAPSAAPAPAAPAPAPAPQSAASSQPQS---------ASTPPALAPGSLLGAAPGL 358 P P A P A P P+ + S P L P G A Sbjct: 433 PGGPQAGEPPPPLAGDKPHKCPECGKGFRRSSDLVKHHRVHTGEKPYLCPECGKGFADSS 492 Query: 359 PSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFF 418 +T P P ++ N P+ + R +A P Sbjct: 493 ARVKHLRTHRGERARPPPPSTLLRPHNPPGPVPMAPRPRV-----------RAQPSGPSQ 541 Query: 419 KHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQ 478 H C FC K F S L H R+HTGE+P+KC CG F R K + H+ Sbjct: 542 PHVCGFCGKEFPRSSDLVKHRRTHTGEKPYKCAECGKGFGDSS------ARIKHQRGHLV 595 Query: 479 MNPYPV 484 + P+ + Sbjct: 596 LTPFGI 601 Score = 39.3 bits (90), Expect = 0.025 Identities = 22/81 (27%), Positives = 32/81 (39%), Gaps = 24/81 (29%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFK------------------------CNICGN 455 +KC C K FG SA H R+H+GE+P++ C CG Sbjct: 140 YKCGVCGKGFGDSSARIKHQRTHSGEKPYRARPPAQGPPKIPRSRIPAGERPTICGECGK 199 Query: 456 RFSTKGNLKVHFQRHKEKYPH 476 F +L H + H + P+ Sbjct: 200 SFRLSSDLVKHQRTHTGEKPY 220 >gi|116256460 zinc finger protein 775 [Homo sapiens] Length = 537 Score = 104 bits (259), Expect = 6e-22 Identities = 79/225 (35%), Positives = 96/225 (42%), Gaps = 49/225 (21%) Query: 978 VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR--------- 1028 +C CGK F S+L IH R HT ERP+ C C R S NL +HL H Sbjct: 282 ICNECGKSFTWWSSLNIHQRIHTGERPYACPECGRRFSQKPNLTRHLRNHTGERPHPCPH 341 Query: 1029 -----------LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEG 1077 LK L + L P P S S A + H +A A+ E Sbjct: 342 CGRGFRQKQHLLKHLRTHL--PGAQAAPCPSCGKSCRSRAA------LRAHQRAHAVAE- 392 Query: 1078 PPLPAGVQVPAGPQTVMGPGLAP-----MLAPPPRRT--------------PKQHNCQSC 1118 P +PAG + PQ PGLA +P R T P+Q C C Sbjct: 393 PAVPAG-EPGDQPQAEAIPGLAARPRSSQRSPGARDTLWGRGQAGLAGPGEPRQFICNEC 451 Query: 1119 GKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 GK+FS SAL IH+R HTGE+P+ C CGR F+ K NL H H Sbjct: 452 GKSFSWWSALTIHQRIHTGERPYPCPECGRRFSQKPNLTRHRRNH 496 Score = 92.8 bits (229), Expect = 2e-18 Identities = 65/196 (33%), Positives = 84/196 (42%), Gaps = 10/196 (5%) Query: 978 VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPS--- 1034 +CG CGK F+ K L H R HT ERPF C C R S +L +H TH S Sbjct: 136 LCGKCGKSFSQKPNLARHQRHHTGERPFCCPECARRFSQKQHLLKHQKTHSRPATHSCPE 195 Query: 1035 --QLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQT 1092 + F L Q + + + + A P P G A Sbjct: 196 CERCFRHQVGLRIHQRAHARDRQGSRAGLHELIQDAAARRACRLQPGPPRGRPEWAWLGL 255 Query: 1093 VMG----PGL-APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICG 1147 G PG A + P P+Q C CGK+F+ S+L IH+R HTGE+P+ C CG Sbjct: 256 CQGWWGQPGARAAVSGPEGPGEPRQFICNECGKSFTWWSSLNIHQRIHTGERPYACPECG 315 Query: 1148 RAFTTKGNLKVHMGTH 1163 R F+ K NL H+ H Sbjct: 316 RRFSQKPNLTRHLRNH 331 Score = 87.8 bits (216), Expect = 6e-17 Identities = 88/314 (28%), Positives = 107/314 (34%), Gaps = 70/314 (22%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481 C C K F S+L IH R HTGERP+ C CG RFS K NL H + H + PH Sbjct: 283 CNECGKSFTWWSSLNIHQRIHTGERPYACPECGRRFSQKPNLTRHLRNHTGERPH----- 337 Query: 482 YPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYA 541 P P G + K + T L PGA A Sbjct: 338 -PCPH--------CGRGFRQKQHLLKHLRTHL---------------------PGAQA-A 366 Query: 542 DSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSL 601 PS + RS A P + E G AE+ L P ++ P Sbjct: 367 PCPSCGKSCRSRAALRAHQRAHAVAEPAVPAGEPGDQPQAEAIPGLAARPRSSQRSP--- 423 Query: 602 PCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPA--VSEQFKAQFPFGGLLDSMQTS 659 A T L PG P + + F + L Q Sbjct: 424 ----------------GARDTLWGRGQAGLAGPGEPRQFICNECGKSFSWWSALTIHQRI 467 Query: 660 ETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTK 719 T + P C C R S + L H R HTGERP+ C CGR F+ K Sbjct: 468 HTGE-------------RPYPCPECGRRFSQKPNLTRHRRNHTGERPYLCPACGRGFSQK 514 Query: 720 GNLKTHFGVHRAKP 733 +L H VHRA P Sbjct: 515 QHLLKHQRVHRAAP 528 Score = 68.6 bits (166), Expect = 4e-11 Identities = 35/90 (38%), Positives = 47/90 (52%), Gaps = 6/90 (6%) Query: 677 DPNQ--CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734 +P Q C C + + S+L +H R HTGERP+ C CGR F+ K NL H H + P Sbjct: 277 EPRQFICNECGKSFTWWSSLNIHQRIHTGERPYACPECGRRFSQKPNLTRHLRNHTGERP 336 Query: 735 LRVQHSCPICQKKFTNAVVLQQHIRMHMGG 764 H CP C + F L +H+R H+ G Sbjct: 337 ----HPCPHCGRGFRQKQHLLKHLRTHLPG 362 Score = 65.5 bits (158), Expect = 3e-10 Identities = 31/81 (38%), Positives = 46/81 (56%), Gaps = 4/81 (4%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740 C+ C + S S+LK+H RTHTGE+P+ C CG++F+ K NL H H + P Sbjct: 109 CLDCGKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARHQRHHTGERPF----C 164 Query: 741 CPICQKKFTNAVVLQQHIRMH 761 CP C ++F+ L +H + H Sbjct: 165 CPECARRFSQKQHLLKHQKTH 185 Score = 64.7 bits (156), Expect = 6e-10 Identities = 35/87 (40%), Positives = 46/87 (52%), Gaps = 6/87 (6%) Query: 677 DPNQ--CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734 +P Q C C + S SAL +H R HTGERP+ C CGR F+ K NL H H + P Sbjct: 442 EPRQFICNECGKSFSWWSALTIHQRIHTGERPYPCPECGRRFSQKPNLTRHRRNHTGERP 501 Query: 735 LRVQHSCPICQKKFTNAVVLQQHIRMH 761 + CP C + F+ L +H R+H Sbjct: 502 ----YLCPACGRGFSQKQHLLKHQRVH 524 Score = 62.4 bits (150), Expect = 3e-09 Identities = 51/161 (31%), Positives = 68/161 (42%), Gaps = 14/161 (8%) Query: 606 ARAGDAPVGAQASAAPTSVDG-----APTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSE 660 A G G+ A PT D AP S P P++S + F Sbjct: 62 ALGGQEESGSPRWAPPTEQDAGLAGRAPGSASGPLSPSLSSG-EGHFVCLDCGKRFSWWS 120 Query: 661 TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720 + K+ Q +K P C C + S + L H R HTGERPF C C R F+ K Sbjct: 121 SLKIHQRTHTGEK----PYLCGKCGKSFSQKPNLARHQRHHTGERPFCCPECARRFSQKQ 176 Query: 721 NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMH 761 +L H H ++P HSCP C++ F + V L+ H R H Sbjct: 177 HLLKHQKTH-SRP---ATHSCPECERCFRHQVGLRIHQRAH 213 Score = 61.6 bits (148), Expect = 5e-09 Identities = 27/49 (55%), Positives = 34/49 (69%) Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 C CGK FS S+L+IH+RTHTGEKP+ C CG++F+ K NL H H Sbjct: 109 CLDCGKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARHQRHH 157 Score = 57.0 bits (136), Expect = 1e-07 Identities = 32/84 (38%), Positives = 36/84 (42%), Gaps = 3/84 (3%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C R S + L H R HTGERP C CGR F K +L H H P Sbjct: 308 PYACPECGRRFSQKPNLTRHLRNHTGERPHPCPHCGRGFRQKQHLLKHLRTHL---PGAQ 364 Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761 CP C K + L+ H R H Sbjct: 365 AAPCPSCGKSCRSRAALRAHQRAH 388 Score = 55.8 bits (133), Expect = 3e-07 Identities = 25/53 (47%), Positives = 31/53 (58%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 K + C CGK+FS L H+R HTGE+PF C C R F+ K +L H TH Sbjct: 133 KPYLCGKCGKSFSQKPNLARHQRHHTGERPFCCPECARRFSQKQHLLKHQKTH 185 Score = 55.1 bits (131), Expect = 4e-07 Identities = 30/65 (46%), Positives = 36/65 (55%), Gaps = 6/65 (9%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481 C C K F S+L+IH R+HTGE+P+ C CG FS K NL H QRH H P Sbjct: 109 CLDCGKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARH-QRH-----HTGERP 162 Query: 482 YPVPE 486 + PE Sbjct: 163 FCCPE 167 Score = 54.7 bits (130), Expect = 6e-07 Identities = 52/167 (31%), Positives = 72/167 (43%), Gaps = 34/167 (20%) Query: 888 SRSAGSPALSESSSSQALSPAPSNGESFRSKSPGLGAP-EEPQE--IPLKTERPDSPAAA 944 +++A P+ +S S+A A + + G P ++PQ IP RP S + Sbjct: 363 AQAAPCPSCGKSCRSRAALRAHQRAHAVAEPAVPAGEPGDQPQAEAIPGLAARPRSSQRS 422 Query: 945 PGSG------GAPGRAGIKEEAPFSLLFLSRERGKCPS-----TV------------CGV 981 PG+ G G AG E F + E GK S T+ C Sbjct: 423 PGARDTLWGRGQAGLAGPGEPRQF----ICNECGKSFSWWSALTIHQRIHTGERPYPCPE 478 Query: 982 CGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR 1028 CG+ F+ K L H R+HT ERP++C C RG S KQHLL H+ Sbjct: 479 CGRRFSQKPNLTRHRRNHTGERPYLCPACGRGFSQ----KQHLLKHQ 521 Score = 52.4 bits (124), Expect = 3e-06 Identities = 47/148 (31%), Positives = 58/148 (39%), Gaps = 21/148 (14%) Query: 332 AASSQPQSAS---TPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALD 388 A Q +S S PP L G APG SASG + P+ L S LD Sbjct: 62 ALGGQEESGSPRWAPPTEQDAGLAGRAPG---------SASGPLSPS-LSSGEGHFVCLD 111 Query: 389 PLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPF 448 R ++ + + + E P+ C C K F L H R HTGERPF Sbjct: 112 -----CGKRFSWWSSLKIHQRTHTGEKPYL---CGKCGKSFSQKPNLARHQRHHTGERPF 163 Query: 449 KCNICGNRFSTKGNLKVHFQRHKEKYPH 476 C C RFS K +L H + H H Sbjct: 164 CCPECARRFSQKQHLLKHQKTHSRPATH 191 Score = 51.2 bits (121), Expect = 6e-06 Identities = 53/216 (24%), Positives = 77/216 (35%), Gaps = 48/216 (22%) Query: 256 SQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPS 315 + LPG A P P+ + AA A + A ++ P A PG +P A A P Sbjct: 358 THLPGAQAAP----CPSCGKSCRSRAALRAHQRAHAVAEPAVPAGEPGD--QPQAEAIPG 411 Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375 A P + +P + + Q+ A PG P + + Sbjct: 412 LAARPRSSQRSPGARDTLWGRGQAGL------------AGPGEPRQFICNECGKSFSW-- 457 Query: 376 PLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSAL 435 SAL H++ + E P+ C C + F L Sbjct: 458 --------------WSALTIHQRIH-----------TGERPY---PCPECGRRFSQKPNL 489 Query: 436 QIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 H R+HTGERP+ C CG FS K +L H + H+ Sbjct: 490 TRHRRNHTGERPYLCPACGRGFSQKQHLLKHQRVHR 525 Score = 47.4 bits (111), Expect = 9e-05 Identities = 25/64 (39%), Positives = 30/64 (46%), Gaps = 3/64 (4%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQM 479 + C C + F L HLR+HTGERP C CG F K +L H + H P Q Sbjct: 309 YACPECGRRFSQKPNLTRHLRNHTGERPHPCPHCGRGFRQKQHLLKHLRTH---LPGAQA 365 Query: 480 NPYP 483 P P Sbjct: 366 APCP 369 Score = 39.7 bits (91), Expect = 0.019 Identities = 18/69 (26%), Positives = 30/69 (43%) Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGR 1174 C C + FS L H++TH+ C C R F + L++H H + +R G Sbjct: 165 CPECARRFSQKQHLLKHQKTHSRPATHSCPECERCFRHQVGLRIHQRAHARDRQGSRAGL 224 Query: 1175 RLSVENPMA 1183 +++ A Sbjct: 225 HELIQDAAA 233 Score = 38.5 bits (88), Expect = 0.042 Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 4/59 (6%) Query: 705 RPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 R F C CG++F+ L H +H + P + CP C ++F+ L +H R H G Sbjct: 444 RQFICNECGKSFSWWSALTIHQRIHTGERP----YPCPECGRRFSQKPNLTRHRRNHTG 498 Score = 38.1 bits (87), Expect = 0.055 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 702 TGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMH 761 +GE F C CG+ F+ +LK H H + P + C C K F+ L +H R H Sbjct: 102 SGEGHFVCLDCGKRFSWWSSLKIHQRTHTGEKP----YLCGKCGKSFSQKPNLARHQRHH 157 Query: 762 MG 763 G Sbjct: 158 TG 159 Score = 34.7 bits (78), Expect = 0.61 Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 5/83 (6%) Query: 3 RRKQAKPQHLKSDEELLPPDGAP---EHAAPGEGAEDADSGP--ESRSGGEETSVCEKCC 57 R+ +P+ L EE P AP + A A + SGP S S GE VC C Sbjct: 54 RQTMGRPRALGGQEESGSPRWAPPTEQDAGLAGRAPGSASGPLSPSLSSGEGHFVCLDCG 113 Query: 58 AEFFKWADFLEHQRSCTKLPPVL 80 F W+ HQR+ T P L Sbjct: 114 KRFSWWSSLKIHQRTHTGEKPYL 136 Score = 32.7 bits (73), Expect = 2.3 Identities = 14/35 (40%), Positives = 21/35 (60%) Query: 443 TGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 +GE F C CG RFS +LK+H + H + P++ Sbjct: 102 SGEGHFVCLDCGKRFSWWSSLKIHQRTHTGEKPYL 136 Score = 32.3 bits (72), Expect = 3.0 Identities = 22/60 (36%), Positives = 25/60 (41%), Gaps = 9/60 (15%) Query: 20 PPDGAPEHAAPG--------EGAEDADSGPESRSGGEETSVCEKCCAEFFKWADFLEHQR 71 PP G PE A G GA A SGPE G +C +C F W+ HQR Sbjct: 243 PPRGRPEWAWLGLCQGWWGQPGARAAVSGPEG-PGEPRQFICNECGKSFTWWSSLNIHQR 301 Score = 32.0 bits (71), Expect = 4.0 Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Query: 1110 PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 P + + G+ SAS + +GE F C CG+ F+ +LK+H TH Sbjct: 77 PTEQDAGLAGRAPGSASG-PLSPSLSSGEGHFVCLDCGKRFSWWSSLKIHQRTH 129 >gi|21699088 zinc finger protein 627 [Homo sapiens] Length = 461 Score = 102 bits (253), Expect = 3e-21 Identities = 56/185 (30%), Positives = 85/185 (45%), Gaps = 24/185 (12%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+C + IH R+HT E+P+ C C + +++ H TH ++L Sbjct: 253 CKQCGKAFSCSKYIRIHERTHTGEKPYECKQCGKAFRCASSVRSHERTHTGEKL------ 306 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 F + ++S MIK NG K G+ P+ ++ T Sbjct: 307 --FECKECGKALTCLASVRRHMIKHTGNGPYKCKVCGKAFDFPSSFRIHERTHT------ 358 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 K ++C+ CGK FS +S+ + HER HTGEKP+ CT CG+AF+ ++ Sbjct: 359 ----------GEKPYDCKQCGKAFSCSSSFRKHERIHTGEKPYKCTKCGKAFSRSSYFRI 408 Query: 1159 HMGTH 1163 H TH Sbjct: 409 HERTH 413 Score = 71.6 bits (174), Expect = 5e-12 Identities = 52/185 (28%), Positives = 83/185 (44%), Gaps = 30/185 (16%) Query: 982 CGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNF 1041 CG+ + + + R+H +P+ C C ++ ++++H+LTHR +P + Sbjct: 144 CGRALSYHRSFPVRERTHPGGKPYDCKECGETFISLVSIRRHMLTHR-GGVPYKCK---- 198 Query: 1042 ALGPSQSTPSL--ISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 G + PSL I + T K E GKA + + +T G Sbjct: 199 VCGKAFDYPSLFRIHERSHTGEKPYECKQCGKAFSCSS--------YIRIHERTHTGD-- 248 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 K + C+ CGK FS + ++IHERTHTGEKP+ C CG+AF +++ Sbjct: 249 ------------KPYECKQCGKAFSCSKYIRIHERTHTGEKPYECKQCGKAFRCASSVRS 296 Query: 1159 HMGTH 1163 H TH Sbjct: 297 HERTH 301 Score = 71.6 bits (174), Expect = 5e-12 Identities = 31/89 (34%), Positives = 50/89 (56%), Gaps = 4/89 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S +++H RTHTG++P++CK CG+AF+ ++ H H + P Sbjct: 222 PYECKQCGKAFSCSSYIRIHERTHTGDKPYECKQCGKAFSCSKYIRIHERTHTGEKP--- 278 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQI 766 + C C K F A ++ H R H G ++ Sbjct: 279 -YECKQCGKAFRCASSVRSHERTHTGEKL 306 Score = 70.1 bits (170), Expect = 1e-11 Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 4/95 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + SC S+ + H R HTGE+P+KC CG+AF+ + H H + P Sbjct: 362 PYDCKQCGKAFSCSSSFRKHERIHTGEKPYKCTKCGKAFSRSSYFRIHERTHTGEKP--- 418 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLP 772 + C C K F+ + + H ++H G + P P Sbjct: 419 -YECKQCGKAFSRSTYFRVHEKIHTGEKPYENPNP 452 Score = 69.7 bits (169), Expect = 2e-11 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C +C + S+ ++H RTHTGE+P+ CK CG+AF+ + + H +H + P Sbjct: 334 PYKCKVCGKAFDFPSSFRIHERTHTGEKPYDCKQCGKAFSCSSSFRKHERIHTGEKP--- 390 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + + H R H G Sbjct: 391 -YKCTKCGKAFSRSSYFRIHERTHTG 415 Score = 65.5 bits (158), Expect = 3e-10 Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C +C + S ++H R+HTGE+P++CK CG+AF+ ++ H H P Sbjct: 194 PYKCKVCGKAFDYPSLFRIHERSHTGEKPYECKQCGKAFSCSSYIRIHERTHTGDKP--- 250 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + ++ H R H G Sbjct: 251 -YECKQCGKAFSCSKYIRIHERTHTG 275 Score = 65.1 bits (157), Expect = 4e-10 Identities = 30/86 (34%), Positives = 44/86 (51%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + C S+++ H RTHTGE+ F+CK CG+A T +++ H H P Sbjct: 278 PYECKQCGKAFRCASSVRSHERTHTGEKLFECKECGKALTCLASVRRHMIKHTGNGP--- 334 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C +C K F + H R H G Sbjct: 335 -YKCKVCGKAFDFPSSFRIHERTHTG 359 Score = 64.3 bits (155), Expect = 7e-10 Identities = 27/84 (32%), Positives = 46/84 (54%), Gaps = 4/84 (4%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 +C C + L+C ++++ H HTG P+KCK+CG+AF + + H H + P + Sbjct: 308 ECKECGKALTCLASVRRHMIKHTGNGPYKCKVCGKAFDFPSSFRIHERTHTGEKP----Y 363 Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763 C C K F+ + ++H R+H G Sbjct: 364 DCKQCGKAFSCSSSFRKHERIHTG 387 Score = 59.3 bits (142), Expect = 2e-08 Identities = 23/57 (40%), Positives = 34/57 (59%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S +IH RSHTGE+P++C CG FS +++H + H P+ Sbjct: 195 YKCKVCGKAFDYPSLFRIHERSHTGEKPYECKQCGKAFSCSSYIRIHERTHTGDKPY 251 Score = 58.9 bits (141), Expect = 3e-08 Identities = 25/62 (40%), Positives = 35/62 (56%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQM 479 +KC C K F S +IH R+HTGE+P++C CG FS +VH + H + P+ Sbjct: 391 YKCTKCGKAFSRSSYFRIHERTHTGEKPYECKQCGKAFSRSTYFRVHEKIHTGEKPYENP 450 Query: 480 NP 481 NP Sbjct: 451 NP 452 Score = 57.4 bits (137), Expect = 9e-08 Identities = 24/76 (31%), Positives = 42/76 (55%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P + E + E P+ +C+ C K F S ++IH R+HTG++P++C CG FS Sbjct: 207 PSLFRIHERSHTGEKPY---ECKQCGKAFSCSSYIRIHERTHTGDKPYECKQCGKAFSCS 263 Query: 461 GNLKVHFQRHKEKYPH 476 +++H + H + P+ Sbjct: 264 KYIRIHERTHTGEKPY 279 Score = 57.0 bits (136), Expect = 1e-07 Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P + + E + E P+ C+ C K F S+ + H R HTGE+P+KC CG FS Sbjct: 347 PSSFRIHERTHTGEKPY---DCKQCGKAFSCSSSFRKHERIHTGEKPYKCTKCGKAFSRS 403 Query: 461 GNLKVHFQRHKEKYPH 476 ++H + H + P+ Sbjct: 404 SYFRIHERTHTGEKPY 419 Score = 56.6 bits (135), Expect = 2e-07 Identities = 22/57 (38%), Positives = 34/57 (59%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S+ +IH R+HTGE+P+ C CG FS + + H + H + P+ Sbjct: 335 YKCKVCGKAFDFPSSFRIHERTHTGEKPYDCKQCGKAFSCSSSFRKHERIHTGEKPY 391 Score = 54.7 bits (130), Expect = 6e-07 Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 7/91 (7%) Query: 673 KKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAK 732 KK NQC R LS + + RTH G +P+ CK CG F + +++ H HR Sbjct: 136 KKSYTRNQC---GRALSYHRSFPVRERTHPGGKPYDCKECGETFISLVSIRRHMLTHRGG 192 Query: 733 PPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 P + C +C K F + + H R H G Sbjct: 193 VP----YKCKVCGKAFDYPSLFRIHERSHTG 219 Score = 53.1 bits (126), Expect = 2e-06 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C +++ H TH G P+KCK+CG+AF + H H + P Sbjct: 166 PYDCKECGETFISLVSIRRHMLTHRGGVPYKCKVCGKAFDYPSLFRIHERSHTGEKP--- 222 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + ++ H R H G Sbjct: 223 -YECKQCGKAFSCSSYIRIHERTHTG 247 Score = 51.2 bits (121), Expect = 6e-06 Identities = 18/51 (35%), Positives = 31/51 (60%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 ++C+ C K F ++IH R+HTGE+P++C CG F +++ H + H Sbjct: 251 YECKQCGKAFSCSKYIRIHERTHTGEKPYECKQCGKAFRCASSVRSHERTH 301 Score = 47.8 bits (112), Expect = 7e-05 Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 3/73 (4%) Query: 404 VSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNL 463 + + E + E P+ +C+ C K F S+++ H R+HTGE+ F+C CG + ++ Sbjct: 266 IRIHERTHTGEKPY---ECKQCGKAFRCASSVRSHERTHTGEKLFECKECGKALTCLASV 322 Query: 464 KVHFQRHKEKYPH 476 + H +H P+ Sbjct: 323 RRHMIKHTGNGPY 335 Score = 46.6 bits (109), Expect = 2e-04 Identities = 16/56 (28%), Positives = 31/56 (55%) Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +C+ C K ++++ H+ HTG P+KC +CG F + ++H + H + P+ Sbjct: 308 ECKECGKALTCLASVRRHMIKHTGNGPYKCKVCGKAFDFPSSFRIHERTHTGEKPY 363 Score = 46.2 bits (108), Expect = 2e-04 Identities = 19/53 (35%), Positives = 28/53 (52%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 K + CG+ S + + ERTH G KP+ C CG F + +++ HM TH Sbjct: 137 KSYTRNQCGRALSYHRSFPVRERTHPGGKPYDCKECGETFISLVSIRRHMLTH 189 Score = 43.5 bits (101), Expect = 0.001 Identities = 16/57 (28%), Positives = 31/57 (54%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 + C+ C + F S +++ H+ +H G P+KC +CG F ++H + H + P+ Sbjct: 167 YDCKECGETFISLVSIRRHMLTHRGGVPYKCKVCGKAFDYPSLFRIHERSHTGEKPY 223 Score = 42.4 bits (98), Expect = 0.003 Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 9/108 (8%) Query: 666 QLVENIDKKMTD---PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNL 722 Q+ + I K T P + +C V S+L H R HTG P + + G+ T+ Sbjct: 85 QIPDGILNKKTPGVKPCESSVCGEVGMGPSSLNRHIRDHTGREPNEYQEYGKKSYTRNQC 144 Query: 723 KTHFGVHRAKP------PLRVQHSCPICQKKFTNAVVLQQHIRMHMGG 764 HR+ P P + C C + F + V +++H+ H GG Sbjct: 145 GRALSYHRSFPVRERTHPGGKPYDCKECGETFISLVSIRRHMLTHRGG 192 Score = 33.9 bits (76), Expect = 1.0 Identities = 12/52 (23%), Positives = 24/52 (46%) Query: 425 CAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 C + + + R+H G +P+ C CG F + +++ H H+ P+ Sbjct: 144 CGRALSYHRSFPVRERTHPGGKPYDCKECGETFISLVSIRRHMLTHRGGVPY 195 Score = 32.0 bits (71), Expect = 4.0 Identities = 21/69 (30%), Positives = 30/69 (43%), Gaps = 12/69 (17%) Query: 1107 RRTPKQHNCQS--CGKTFSSASALQIHERTHTGEKP----------FGCTICGRAFTTKG 1154 ++TP C+S CG+ S+L H R HTG +P + CGRA + Sbjct: 93 KKTPGVKPCESSVCGEVGMGPSSLNRHIRDHTGREPNEYQEYGKKSYTRNQCGRALSYHR 152 Query: 1155 NLKVHMGTH 1163 + V TH Sbjct: 153 SFPVRERTH 161 >gi|51173737 ras responsive element binding protein 1 isoform 1 [Homo sapiens] Length = 1742 Score = 98.2 bits (243), Expect = 5e-20 Identities = 153/635 (24%), Positives = 238/635 (37%), Gaps = 146/635 (22%) Query: 475 PHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTV 534 P + + PV E L + + + I +S P T D P T+ L +V Sbjct: 1049 PPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVADPGPASTGSNTTASDSLGGSV 1108 Query: 535 PGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAES----------P 584 P A A + T S + P+PASS A+ SP E G + T++ P Sbjct: 1109 PKAATTATPAATTSPKESSEPPAPASSPEAA-SP----TEQGPAGTSKKRGRKRGMRSRP 1163 Query: 585 QSLLGGPPLTKAEPVS-----LPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAV 639 ++ GG L + + L T+ + V GAP P Sbjct: 1164 RANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDNTQDEVAGAPADHHGP----- 1218 Query: 640 SEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYR 699 S++ + P LL + + S T+ LQ++ C C RV S+L+ H Sbjct: 1219 SDEEQGSPPEDKLLRAKRNSYTNCLQKIT------------CPHCPRVFPWASSLQRHML 1266 Query: 700 THTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIR 759 THTG++PF C+ C F+TK N + H LR +H C Sbjct: 1267 THTGQKPFPCQKCDAFFSTKSNCERH--------QLR-KHGVTTCS-------------- 1303 Query: 760 MHMGGQIPNTPLPE-GFQDAMDSELAYDDKNAETLSSYDDDMDENSMEDDAELKDAATDP 818 + G IP + + G D+ DS+ +AET ++ + +D S + ++ ++ Sbjct: 1304 LRRNGLIPQSKESDVGSHDSTDSQ-----SDAETAAAAGEVLDLTSRD-----REQPSEG 1353 Query: 819 AKPLLSYAGSCPPSPPSVISSIAALENQMKMIDSVMSCQQLTGLKSVENGSGESDRLSND 878 A L AG P + ++ + +S ++ E +G++D D Sbjct: 1354 ATELRQVAGDAPVEQATAETASPVHREEHGRGESHEPEEE----HGTEESTGDADGAEED 1409 Query: 879 SSS-----------------AVGDLESRSAGSPALSESSSSQALSPAPSNGESFR----- 916 +SS A GD E+ + G+ +S Q L+ + G+SF+ Sbjct: 1410 ASSNQSLDLDFATKLMDFKLAEGDGEAGAGGA-----ASQEQKLA-CDTCGKSFKFLGTL 1463 Query: 917 --------------SKSPGLGAPEE-PQEIPLKTER-PDSPA----AAPGSGGAPGRAGI 956 K G EE PQ P + E+ P++PA +APG+G AP Sbjct: 1464 SRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQEEKPPETPAEVVESAPGAGEAPAEKLA 1523 Query: 957 KE-EAPFSLLFLSRERG-------KCPST---------------VCGVCGKPFACKSALE 993 +E E P + +R K P T VC VC K F L Sbjct: 1524 EETEGPSDGESAAEKRSSEKSDDDKKPKTDSPKSVASKADKRKKVCSVCNKRFWSLQDLT 1583 Query: 994 IHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR 1028 H RSHT ERP+ C C R + +L +H H+ Sbjct: 1584 RHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQ 1618 Score = 80.9 bits (198), Expect = 7e-15 Identities = 118/498 (23%), Positives = 183/498 (36%), Gaps = 55/498 (11%) Query: 11 HLKSDEELLPPDGAPEHAAPGEGAEDADSGPESRSGGEETSVCEKCCAEFFKWADFLEHQ 70 H+ +P + +G A++ SG E S C + FLE Q Sbjct: 808 HILKQHLHVPEQDIESYVLAADGLGPAEAPAAEASGRGEDSGCA-ALGDCKPLTAFLEPQ 866 Query: 71 -----RSCTKLPPVLIVHEDAPAPP-PEDFPEPSPAS-----------------SPSERA 107 R T+ PP + + PA DF EP S SPS Sbjct: 867 NGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPLDFSQKGLALVQVKQENISFLSPSSLV 926 Query: 108 ESEAAEEAGAEGAEGEARPVEKE-AEPMDA----EPAGDTRAPRPPPAAPAPPTPAYGAP 162 + + E R +K+ A P +A E AG + P P PA P P P P Sbjct: 927 PYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPEEEAGSSEQPSPCPA-PGPSLPVTLGP 985 Query: 163 STNVTLEALLSTKVAVAQFSQGARAAGGSGAGGGVAAAAVPLILEQLMAL-----QQQQI 217 S +L + +A A A + G AVP+ L++ + Sbjct: 986 S------GILESPMAPAP---AATPEPPAQPLQGPVQLAVPIYSSALVSSPPLVGSSALL 1036 Query: 218 HQLQLIEQIRSQVALM-QRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIA 276 L+ +R + L+ +PP L P A+ + + S P L L P A Sbjct: 1037 SGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTL--LKTKVADPGPAST 1094 Query: 277 GSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAP-APAPQSAASS 335 GS A + G+ P + + + P E S P AP+++P A+P PA S Sbjct: 1095 GSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAASPTEQGPAGTSKKRG 1154 Query: 336 QPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMK 395 + + + P G + + G + + + + +P + A + A Sbjct: 1155 RKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDNTQDEVAGAPAD 1214 Query: 396 HR------KGKPPNVSVFEPKASA-EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPF 448 H +G PP + K ++ + K C C +VF S+LQ H+ +HTG++PF Sbjct: 1215 HHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQRHMLTHTGQKPF 1274 Query: 449 KCNICGNRFSTKGNLKVH 466 C C FSTK N + H Sbjct: 1275 PCQKCDAFFSTKSNCERH 1292 Score = 68.9 bits (167), Expect = 3e-11 Identities = 27/51 (52%), Positives = 37/51 (72%) Query: 1113 HNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 H+C CGK+ SSAS+L H H+GE+P+ CT+CG++FTT GN+ HM H Sbjct: 97 HSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH 147 Score = 68.2 bits (165), Expect = 5e-11 Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 7/125 (5%) Query: 609 GDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLV 668 G +P G ++ + P P +G E+ P + + Q T ++Q Sbjct: 34 GGSPQGIKSPSKPPG----PNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQ-- 87 Query: 669 ENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGV 728 N D D + C IC + LS S+L H H+GERP+KC +CG++FTT GN+ H + Sbjct: 88 HNTDTGGAD-HSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKI 146 Query: 729 HRAKP 733 H P Sbjct: 147 HEKDP 151 Score = 65.9 bits (159), Expect = 2e-10 Identities = 75/265 (28%), Positives = 104/265 (39%), Gaps = 36/265 (13%) Query: 219 QLQLIEQIRSQVALMQRPPPRPSLSP-AAAPSAPGPAP-SQLPGLAALPLSAGAPAAAIA 276 +L I+QI A PP+ SL P + AP+AP A +P L PL P +A Sbjct: 466 ELADIQQILKMAA---SAPPQISLPPFSKAPAAPLQAIFKHMPPLKPKPLVT--PRTVVA 520 Query: 277 GSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAP--QSAAS 334 S P + A P G PS P P + A + A QS + Sbjct: 521 TSTPPPLINAQQASP------------GCISPSLPPPPLKLLKGSVEAASNAHLLQSKSG 568 Query: 335 SQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALM 394 +QP +A+ P + L P + + L Q S + P + + L A M Sbjct: 569 TQPHAATRLSLQQPRAELPGQPEMKTQL-EQDSIIEALLPLSMEAKIKQEITEGELKAFM 627 Query: 395 KHRKGK--PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNI 452 GK P V P CRFC +VF L+ H+RSH G P++CNI Sbjct: 628 TAPGGKKTPAMRKVLYP------------CRFCNQVFAFSGVLRAHVRSHLGISPYQCNI 675 Query: 453 CGNRFSTKGNLKVHFQRHKEKYPHI 477 C + K L H + H + P+I Sbjct: 676 CDYIAADKAALIRHLRTHSGERPYI 700 Score = 62.4 bits (150), Expect = 3e-09 Identities = 53/216 (24%), Positives = 81/216 (37%), Gaps = 26/216 (12%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C +CGK + S+L+ H H+ ERP+ C +C + +T GN+ +H+ H D Sbjct: 99 CSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEK--------D 150 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 PN A + +P L + K+ + + P PA V G + Sbjct: 151 PNSATATAPPSP-LKRRRLSSKRKLSHDAESE-----REDPAPAKKMVEDGQSGDL---- 200 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 ++ + +C C K F L+ H TH+ + P C IC F T L Sbjct: 201 -------EKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLR 252 Query: 1159 HMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSE 1194 H GR NP G L F++ Sbjct: 253 HNALVHKQLPRDAMGRPFIQNNPSIPAGFHDLGFTD 288 Score = 61.2 bits (147), Expect = 6e-09 Identities = 26/57 (45%), Positives = 35/57 (61%), Gaps = 1/57 (1%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 H C C K S S+L H+ H+GERP+KC +CG F+T GN+ H + H EK P+ Sbjct: 97 HSCSICGKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIH-EKDPN 152 Score = 58.9 bits (141), Expect = 3e-08 Identities = 70/245 (28%), Positives = 98/245 (40%), Gaps = 53/245 (21%) Query: 503 LPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSP---- 558 +PP KP KP++ T T V PP + A A+P SP P P Sbjct: 504 MPPLKP-------KPLV-TPRTVVATSTPPPLINAQ------QASPGCISPSLPPPPLKL 549 Query: 559 --ASSECASLSPGLNHVESGVSATA------ESPQSLLGGPPLTKAEPVSLPCTNARAGD 610 S E AS + L +SG A + P++ L G P K + L + Sbjct: 550 LKGSVEAAS-NAHLLQSKSGTQPHAATRLSLQQPRAELPGQPEMKTQ---LEQDSIIEAL 605 Query: 611 APVGAQASAAPTSVDGA----PTSLGSPGLPAVSE-----QFKAQ-FPFGGLLDSMQTSE 660 P+ +A +G T+ G PA+ + +F Q F F G+L + S Sbjct: 606 LPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSH 665 Query: 661 TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720 P QC IC + + ++AL H RTH+GERP+ CKIC FT K Sbjct: 666 LG-------------ISPYQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKA 712 Query: 721 NLKTH 725 N + H Sbjct: 713 NCERH 717 Score = 56.2 bits (134), Expect = 2e-07 Identities = 47/191 (24%), Positives = 66/191 (34%), Gaps = 63/191 (32%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C +C A K+AL H R+H+ ERP++C +C + N ++HL LK + Sbjct: 673 CNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDI-- 730 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 + +SS+A + V P TV Sbjct: 731 --------EKNIEYVSSSAAEL-----------------------VDAFCAPDTV----- 754 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERT---------HTGEKPFGCTICGRA 1149 C+ CG+ AL+IH RT H G KPF C C A Sbjct: 755 ----------------CRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAA 798 Query: 1150 FTTKGNLKVHM 1160 F K N H+ Sbjct: 799 FAAKRNCIHHI 809 Score = 55.5 bits (132), Expect = 3e-07 Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 7/84 (8%) Query: 681 CVICHRVLSCQSALKMHYRTH---TGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 C +C ++ + Q L MH R H TG C ICG++ ++ +L H VH + P Sbjct: 68 CPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERP--- 124 Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761 + C +C + FT + +H+++H Sbjct: 125 -YKCTVCGQSFTTNGNMHRHMKIH 147 Score = 55.5 bits (132), Expect = 3e-07 Identities = 51/169 (30%), Positives = 69/169 (40%), Gaps = 20/169 (11%) Query: 304 GPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLL 363 G EP A+ A P PAP + P++ + APG+ G AP L Sbjct: 1471 GRQEPKDEKGDGASTAEEGPQPAPEQEE---KPPETPAEVVESAPGA--GEAPA--EKLA 1523 Query: 364 PQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCR 423 +T P+ S A ++ K K P + AS D K C Sbjct: 1524 EETEG-----PSDGESAAEKRSS-------EKSDDDKKPKTDSPKSVASKADKR-KKVCS 1570 Query: 424 FCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKE 472 C K F S L H+RSHTGERP+KC C F+ K +L H + H++ Sbjct: 1571 VCNKRFWSLQDLTRHMRSHTGERPYKCQTCERTFTLKHSLVRHQRIHQK 1619 Score = 54.3 bits (129), Expect = 7e-07 Identities = 96/416 (23%), Positives = 142/416 (34%), Gaps = 92/416 (22%) Query: 422 CRFCAKVFGSDSALQIHLRSHTG-----ERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 C C K F +L +H ++H E+P + G+ KG L + +H + Sbjct: 318 CDTCDKAFPMLCSLALHKQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTK---- 373 Query: 477 IQMNPYPVPEYL--DN-----------VPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVP 523 + P P E L DN +P G +SL P + + S VLP Sbjct: 374 -DVRPAPAEEPLPDDNQAIQLQTLKCQLPQDPGCTNLLSLSPFEAASLG-GSLTVLPATK 431 Query: 524 TSVG-LQLPPTVPGAHGYADSPSATP--------------------ASRSPQRPSPASSE 562 S+ L L P G DS AS PQ P S+ Sbjct: 432 DSIKHLSLQPFQKGFIIQPDSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPFSK 491 Query: 563 C--ASLSPGLNHVESGVSATAESPQSLLGG---PPLTKAEPVSLPC-------------- 603 A L H+ +P++++ PPL A+ S C Sbjct: 492 APAAPLQAIFKHMPPLKPKPLVTPRTVVATSTPPPLINAQQASPGCISPSLPPPPLKLLK 551 Query: 604 ------TNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQ 657 +NA + G Q AA T + PG P + Q + LL Sbjct: 552 GSVEAASNAHLLQSKSGTQPHAA-TRLSLQQPRAELPGQPEMKTQLEQDSIIEALLP--- 607 Query: 658 TSETSKLQQLVENIDKK--MTDPN------------QCVICHRVLSCQSALKMHYRTHTG 703 S +K++Q + + K MT P C C++V + L+ H R+H G Sbjct: 608 LSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLG 667 Query: 704 ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIR 759 P++C IC K L H H + P + C IC FT ++H+R Sbjct: 668 ISPYQCNICDYIAADKAALIRHLRTHSGERP----YICKICHYPFTVKANCERHLR 719 Score = 49.7 bits (117), Expect = 2e-05 Identities = 22/45 (48%), Positives = 27/45 (60%) Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVH 1159 C C + F AS+LQ H THTG+KPF C C F+TK N + H Sbjct: 1248 CPHCPRVFPWASSLQRHMLTHTGQKPFPCQKCDAFFSTKSNCERH 1292 Score = 47.8 bits (112), Expect = 7e-05 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 4/88 (4%) Query: 1080 LPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHN----CQSCGKTFSSASALQIHERTH 1135 LP ++ + G A M AP ++TP C+ C + F+ + L+ H R+H Sbjct: 606 LPLSMEAKIKQEITEGELKAFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSH 665 Query: 1136 TGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 G P+ C IC K L H+ TH Sbjct: 666 LGISPYQCNICDYIAADKAALIRHLRTH 693 Score = 44.3 bits (103), Expect = 8e-04 Identities = 19/48 (39%), Positives = 27/48 (56%) Query: 1113 HNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHM 1160 + C C + +AL H RTH+GE+P+ C IC FT K N + H+ Sbjct: 671 YQCNICDYIAADKAALIRHLRTHSGERPYICKICHYPFTVKANCERHL 718 Score = 42.7 bits (99), Expect = 0.002 Identities = 31/133 (23%), Positives = 53/133 (39%), Gaps = 11/133 (8%) Query: 1081 PAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTH---TG 1137 P G++ P+ P GP + +NC C K ++ L +H R H TG Sbjct: 37 PQGIKSPSKPP---GPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTG 93 Query: 1138 EKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVENPMALLGGDALKFSEMFQ 1197 C+ICG++ ++ +L HM H R + +V G+ + ++ + Sbjct: 94 GADHSCSICGKSLSSASSLDRHMLVH-----SGERPYKCTVCGQSFTTNGNMHRHMKIHE 148 Query: 1198 KDLAARAMNVDPS 1210 KD + PS Sbjct: 149 KDPNSATATAPPS 161 Score = 42.0 bits (97), Expect = 0.004 Identities = 54/224 (24%), Positives = 76/224 (33%), Gaps = 67/224 (29%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTM----GNLKQHLLTHRLKELPS 1034 C VC K F CK LE H +H+ + P C +C C T G L+ + L H K+LP Sbjct: 210 CPVCFKEFVCKYGLETHMETHS-DNPLRCDIC---CVTFRTHRGLLRHNALVH--KQLPR 263 Query: 1035 QLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGV---------- 1084 F + P +PAG Sbjct: 264 DAMGRPF--------------------------------IQNNPSIPAGFHDLGFTDFSC 291 Query: 1085 -QVPAGPQTVMGPGLAPMLAPPPRRTPKQHN--CQSCGKTFSSASALQIHERTHTG---- 1137 + P Q L ++ +QH C +C K F +L +H++TH Sbjct: 292 RKFPRISQAWCETNLRRCIS-------EQHRFVCDTCDKAFPMLCSLALHKQTHVAADQG 344 Query: 1138 -EKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPARRGRRLSVEN 1180 EKP + G A KG L + H + PA L +N Sbjct: 345 QEKPQATPLPGDALDQKGFLALLGLQHTKDVRPAPAEEPLPDDN 388 Score = 40.4 bits (93), Expect = 0.011 Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%) Query: 670 NIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTT-KGNLKTHFGV 728 +++KK + C +C + C+ L+ H TH+ + P +C IC F T +G L+ + V Sbjct: 199 DLEKKADEVFHCPVCFKEFVCKYGLETHMETHS-DNPLRCDICCVTFRTHRGLLRHNALV 257 Query: 729 HRAKP 733 H+ P Sbjct: 258 HKQLP 262 Score = 40.4 bits (93), Expect = 0.011 Identities = 43/161 (26%), Positives = 63/161 (39%), Gaps = 26/161 (16%) Query: 975 PSTVCGVCGKPFACKSALEIHYRS---------HTKERPFVCALCRRGCSTMGNLKQHLL 1025 P TVC +CG+ AL IH R+ H +PF C C + N H+L Sbjct: 751 PDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHIL 810 Query: 1026 THRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGK---AMALGEGPPLPA 1082 L +P Q + ++ L P+ +A E +G G+ ALG+ PL A Sbjct: 811 KQHL-HVPEQDIE-SYVLAADGLGPAEAPAA-------EASGRGEDSGCAALGDCKPLTA 861 Query: 1083 GVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFS 1123 ++ G + G P PPP + K S F+ Sbjct: 862 FLEPQNG---FLHRG--PTQPPPPHVSIKLEPASSFAVDFN 897 Score = 40.0 bits (92), Expect = 0.015 Identities = 59/260 (22%), Positives = 88/260 (33%), Gaps = 49/260 (18%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGE---------RPFKCNICGNRFSTKGNLKVHFQRHKE 472 CR C + AL+IH+R+H G +PF+C C F+ K N H + Sbjct: 755 CRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAKRNCIHHILKQHL 814 Query: 473 KYPHIQMNPYPVPE---YLDNVPTCSGIPYG-----MSLPPEKPVTTWLDSKPVLPTVPT 524 P + Y + P G +L KP+T +L+ P Sbjct: 815 HVPEQDIESYVLAADGLGPAEAPAAEASGRGEDSGCAALGDCKPLTAFLE--------PQ 866 Query: 525 SVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAE-- 582 + L PT P P + PASS + L+ + G++ Sbjct: 867 NGFLHRGPTQP------------PPPHVSIKLEPASSFAVDFNEPLDFSQKGLALVQVKQ 914 Query: 583 ------SPQSLLGGPPLTKAEPVSLPC-TNARAGDAPVGAQASAAPTSVDGAPTSLGSPG 635 SP SL+ P EP+ L N R GD + + A + + SP Sbjct: 915 ENISFLSPSSLV--PYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPEEEAGSSEQPSP- 971 Query: 636 LPAVSEQFKAQFPFGGLLDS 655 PA G+L+S Sbjct: 972 CPAPGPSLPVTLGPSGILES 991 Score = 39.3 bits (90), Expect = 0.025 Identities = 22/66 (33%), Positives = 28/66 (42%), Gaps = 9/66 (13%) Query: 669 ENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGE---------RPFKCKICGRAFTTK 719 E +D C +C L AL++H RTH G +PF+CK C AF K Sbjct: 743 ELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGGHKGRKPFECKECSAAFAAK 802 Query: 720 GNLKTH 725 N H Sbjct: 803 RNCIHH 808 Score = 38.9 bits (89), Expect = 0.032 Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 1/69 (1%) Query: 695 KMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVL 754 + + T + + C +C + TT+ L H H HSC IC K ++A L Sbjct: 54 RRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTG-GADHSCSICGKSLSSASSL 112 Query: 755 QQHIRMHMG 763 +H+ +H G Sbjct: 113 DRHMLVHSG 121 Score = 38.9 bits (89), Expect = 0.032 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 420 HKCRFCAKVFGSDSALQIHLRSH---TGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 + C C K+ + L +H+R H TG C+ICG S+ +L H H + P+ Sbjct: 66 YNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSICGKSLSSASSLDRHMLVHSGERPY 125 Score = 36.2 bits (82), Expect = 0.21 Identities = 17/49 (34%), Positives = 22/49 (44%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 C C + FA L H RSH P+ C +C + L +HL TH Sbjct: 645 CRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAADKAALIRHLRTH 693 Score = 35.0 bits (79), Expect = 0.47 Identities = 37/163 (22%), Positives = 61/163 (37%), Gaps = 32/163 (19%) Query: 14 SDEELLPPDGAPEHAAPGEGAE---------------DADSGPESRSGGEETSVCEKCCA 58 ++E DGA E A+ + + D ++G + E+ C+ C Sbjct: 1396 TEESTGDADGAEEDASSNQSLDLDFATKLMDFKLAEGDGEAGAGGAASQEQKLACDTCGK 1455 Query: 59 EFFKWADFLEHQRSCTKLPPV------LIVHEDAPAPPPEDFPEPSPASSPSERAES--- 109 F H+++ + P E+ P P PE E P +P+E ES Sbjct: 1456 SFKFLGTLSRHRKAHGRQEPKDEKGDGASTAEEGPQPAPEQ--EEKPPETPAEVVESAPG 1513 Query: 110 --EAAEEAGAEGAEG----EARPVEKEAEPMDAEPAGDTRAPR 146 EA E AE EG E+ ++ +E D + T +P+ Sbjct: 1514 AGEAPAEKLAEETEGPSDGESAAEKRSSEKSDDDKKPKTDSPK 1556 Score = 34.3 bits (77), Expect = 0.80 Identities = 16/57 (28%), Positives = 24/57 (42%), Gaps = 4/57 (7%) Query: 707 FKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 + C+ C + F G L+ H H P + C IC + L +H+R H G Sbjct: 643 YPCRFCNQVFAFSGVLRAHVRSHLGISP----YQCNICDYIAADKAALIRHLRTHSG 695 >gi|4507987 zinc finger protein 136 [Homo sapiens] Length = 540 Score = 97.4 bits (241), Expect = 8e-20 Identities = 63/192 (32%), Positives = 85/192 (44%), Gaps = 10/192 (5%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037 C VCGKPF S+ ++H R HT E+PF C C + S L+ H TH K + Sbjct: 254 CKVCGKPFHSLSSFQVHERIHTGEKPFKCKQCGKAFSCSPTLRIHERTHTGEKPYECKQC 313 Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097 F+ PS I + + + GKA + P G Sbjct: 314 GKAFSYLPSLRLHERIHTGEKPFVCKQC---GKAFRSASTFQIHERTHTGEKPYECKECG 370 Query: 1098 LAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151 A P RR +H C+ CGK F S S +IHERTHTGEKP+ C CG+AF Sbjct: 371 EAFSCIPSMRRHMIKHTGEGPYKCKVCGKPFHSLSPFRIHERTHTGEKPYVCKHCGKAFV 430 Query: 1152 TKGNLKVHMGTH 1163 + ++++H TH Sbjct: 431 SSTSIRIHERTH 442 Score = 89.7 bits (221), Expect = 2e-17 Identities = 62/200 (31%), Positives = 90/200 (45%), Gaps = 12/200 (6%) Query: 978 VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037 VC CGK F S +IH R+HT E+P+ C C S + ++++H++ H E P + Sbjct: 337 VCKQCGKAFRSASTFQIHERTHTGEKPYECKECGEAFSCIPSMRRHMIKHT-GEGP---Y 392 Query: 1038 DPNFALGPSQS-TPSLISSAAPTMIKMEVNGH-GKAMALGEGPPLPAGVQVPAGPQTVMG 1095 P S +P I T K V H GKA + P Sbjct: 393 KCKVCGKPFHSLSPFRIHERTHTGEKPYVCKHCGKAFVSSTSIRIHERTHTGEKPYECKQ 452 Query: 1096 PGLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149 G A R H C+ CGK F S+S+ ++HERTHTG+KP+ C CG+A Sbjct: 453 CGKAFSYLNSFRTHEMIHTGEKPFECKRCGKAFRSSSSFRLHERTHTGQKPYHCKECGKA 512 Query: 1150 FTTKGNLKVHMGTHMWNNAP 1169 ++ + + + HM TH + P Sbjct: 513 YSCRASFQRHMLTHAEDGPP 532 Score = 76.6 bits (187), Expect = 1e-13 Identities = 63/227 (27%), Positives = 97/227 (42%), Gaps = 33/227 (14%) Query: 969 RERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH- 1027 +E G+ P T C KPF+ + H HT E+ + C C + ++ +++H++TH Sbjct: 133 QEYGEKPDTR-NQCWKPFSSHHSFRTHEIIHTGEKLYDCKECGKTFFSLKRIRRHIITHS 191 Query: 1028 -----------RLKELPSQL--------FDPNFALGPSQSTPSLISSAAPTMIKMEVNGH 1068 + + PS+ + + + I+S MIK +G Sbjct: 192 GYTPYKCKVCGKAFDYPSRFRTHERSHTGEKPYECQECGKAFTCITSVRRHMIKHTGDGP 251 Query: 1069 GKAMALGEGPPLPAGVQVPAGPQTVMGP------GLAPMLAPPPR---RT---PKQHNCQ 1116 K G+ + QV T P G A +P R RT K + C+ Sbjct: 252 YKCKVCGKPFHSLSSFQVHERIHTGEKPFKCKQCGKAFSCSPTLRIHERTHTGEKPYECK 311 Query: 1117 SCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 CGK FS +L++HER HTGEKPF C CG+AF + ++H TH Sbjct: 312 QCGKAFSYLPSLRLHERIHTGEKPFVCKQCGKAFRSASTFQIHERTH 358 Score = 73.9 bits (180), Expect = 9e-13 Identities = 34/86 (39%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC L++H RTHTGE+P++CK CG+AF+ +L+ H +H + P Sbjct: 279 PFKCKQCGKAFSCSPTLRIHERTHTGEKPYECKQCGKAFSYLPSLRLHERIHTGEKPF-- 336 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 C C K F +A Q H R H G Sbjct: 337 --VCKQCGKAFRSASTFQIHERTHTG 360 Score = 69.3 bits (168), Expect = 2e-11 Identities = 32/86 (37%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C +C + S+ ++H R HTGE+PFKCK CG+AF+ L+ H H + P Sbjct: 251 PYKCKVCGKPFHSLSSFQVHERIHTGEKPFKCKQCGKAFSCSPTLRIHERTHTGEKP--- 307 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ L+ H R+H G Sbjct: 308 -YECKQCGKAFSYLPSLRLHERIHTG 332 Score = 66.2 bits (160), Expect = 2e-10 Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C +C + S + H R+HTGE+P++C+ CG+AFT +++ H H P Sbjct: 195 PYKCKVCGKAFDYPSRFRTHERSHTGEKPYECQECGKAFTCITSVRRHMIKHTGDGP--- 251 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C +C K F + Q H R+H G Sbjct: 252 -YKCKVCGKPFHSLSSFQVHERIHTG 276 Score = 66.2 bits (160), Expect = 2e-10 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + +++++H RTHTGE+P++CK CG+AF+ + +TH +H + P Sbjct: 419 PYVCKHCGKAFVSSTSIRIHERTHTGEKPYECKQCGKAFSYLNSFRTHEMIHTGEKPF-- 476 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 C C K F ++ + H R H G Sbjct: 477 --ECKRCGKAFRSSSSFRLHERTHTG 500 Score = 64.7 bits (156), Expect = 6e-10 Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + +C ++++ H HTG+ P+KCK+CG+ F + + + H +H + P + Sbjct: 223 PYECQECGKAFTCITSVRRHMIKHTGDGPYKCKVCGKPFHSLSSFQVHERIHTGEKPFK- 281 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 C C K F+ + L+ H R H G Sbjct: 282 ---CKQCGKAFSCSPTLRIHERTHTG 304 Score = 63.5 bits (153), Expect = 1e-09 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C +C + S ++H RTHTGE+P+ CK CG+AF + +++ H H + P Sbjct: 391 PYKCKVCGKPFHSLSPFRIHERTHTGEKPYVCKHCGKAFVSSTSIRIHERTHTGEKP--- 447 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + H +H G Sbjct: 448 -YECKQCGKAFSYLNSFRTHEMIHTG 472 Score = 63.2 bits (152), Expect = 2e-09 Identities = 26/57 (45%), Positives = 36/57 (63%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S S+ Q+H R HTGE+PFKC CG FS L++H + H + P+ Sbjct: 252 YKCKVCGKPFHSLSSFQVHERIHTGEKPFKCKQCGKAFSCSPTLRIHERTHTGEKPY 308 Score = 63.2 bits (152), Expect = 2e-09 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C SC +++ H HTGE P+KCK+CG+ F + + H H + P Sbjct: 363 PYECKECGEAFSCIPSMRRHMIKHTGEGPYKCKVCGKPFHSLSPFRIHERTHTGEKP--- 419 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F ++ ++ H R H G Sbjct: 420 -YVCKHCGKAFVSSTSIRIHERTHTG 444 Score = 62.4 bits (150), Expect = 3e-09 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + S ++H RTHTGE+P++CK CG AF+ +++ H H + P Sbjct: 335 PFVCKQCGKAFRSASTFQIHERTHTGEKPYECKECGEAFSCIPSMRRHMIKHTGEGP--- 391 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C +C K F + + H R H G Sbjct: 392 -YKCKVCGKPFHSLSPFRIHERTHTG 416 Score = 62.0 bits (149), Expect = 4e-09 Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S +L++H R HTGE+PF CK CG+AF + + H H + P Sbjct: 307 PYECKQCGKAFSYLPSLRLHERIHTGEKPFVCKQCGKAFRSASTFQIHERTHTGEKP--- 363 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C + F+ +++H+ H G Sbjct: 364 -YECKECGEAFSCIPSMRRHMIKHTG 388 Score = 60.1 bits (144), Expect = 1e-08 Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 4/84 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S ++ + H HTGE+PF+CK CG+AF + + + H H + P Sbjct: 447 PYECKQCGKAFSYLNSFRTHEMIHTGEKPFECKRCGKAFRSSSSFRLHERTHTGQKP--- 503 Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761 + C C K ++ Q+H+ H Sbjct: 504 -YHCKECGKAYSCRASFQRHMLTH 526 Score = 59.7 bits (143), Expect = 2e-08 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 7/83 (8%) Query: 399 GKP----PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICG 454 GKP + V E + E PF KC+ C K F L+IH R+HTGE+P++C CG Sbjct: 258 GKPFHSLSSFQVHERIHTGEKPF---KCKQCGKAFSCSPTLRIHERTHTGEKPYECKQCG 314 Query: 455 NRFSTKGNLKVHFQRHKEKYPHI 477 FS +L++H + H + P + Sbjct: 315 KAFSYLPSLRLHERIHTGEKPFV 337 Score = 59.7 bits (143), Expect = 2e-08 Identities = 28/75 (37%), Positives = 43/75 (57%), Gaps = 3/75 (4%) Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKG 461 P++ + E + E PF C+ C K F S S QIH R+HTGE+P++C CG FS Sbjct: 321 PSLRLHERIHTGEKPFV---CKQCGKAFRSASTFQIHERTHTGEKPYECKECGEAFSCIP 377 Query: 462 NLKVHFQRHKEKYPH 476 +++ H +H + P+ Sbjct: 378 SMRRHMIKHTGEGPY 392 Score = 57.4 bits (137), Expect = 9e-08 Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 4/83 (4%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740 C C + ++ H TH+G P+KCK+CG+AF +TH H + P + Sbjct: 170 CKECGKTFFSLKRIRRHIITHSGYTPYKCKVCGKAFDYPSRFRTHERSHTGEKP----YE 225 Query: 741 CPICQKKFTNAVVLQQHIRMHMG 763 C C K FT +++H+ H G Sbjct: 226 CQECGKAFTCITSVRRHMIKHTG 248 Score = 57.4 bits (137), Expect = 9e-08 Identities = 25/67 (37%), Positives = 40/67 (59%), Gaps = 3/67 (4%) Query: 410 KASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQR 469 K + E P+ KC+ C K F S S +IH R+HTGE+P+ C CG F + ++++H + Sbjct: 385 KHTGEGPY---KCKVCGKPFHSLSPFRIHERTHTGEKPYVCKHCGKAFVSSTSIRIHERT 441 Query: 470 HKEKYPH 476 H + P+ Sbjct: 442 HTGEKPY 448 Score = 55.8 bits (133), Expect = 3e-07 Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 3/64 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + E PF +C+ C K F S S+ ++H R+HTG++P+ C CG +S + + + H H Sbjct: 471 TGEKPF---ECKRCGKAFRSSSSFRLHERTHTGQKPYHCKECGKAYSCRASFQRHMLTHA 527 Query: 472 EKYP 475 E P Sbjct: 528 EDGP 531 Score = 55.5 bits (132), Expect = 3e-07 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 3/75 (4%) Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKG 461 P + + E + E P+ +C+ C K F +L++H R HTGE+PF C CG F + Sbjct: 293 PTLRIHERTHTGEKPY---ECKQCGKAFSYLPSLRLHERIHTGEKPFVCKQCGKAFRSAS 349 Query: 462 NLKVHFQRHKEKYPH 476 ++H + H + P+ Sbjct: 350 TFQIHERTHTGEKPY 364 Score = 55.5 bits (132), Expect = 3e-07 Identities = 24/70 (34%), Positives = 39/70 (55%), Gaps = 3/70 (4%) Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465 + E + E P+ C+ C K F S ++++IH R+HTGE+P++C CG FS + + Sbjct: 409 IHERTHTGEKPYV---CKHCGKAFVSSTSIRIHERTHTGEKPYECKQCGKAFSYLNSFRT 465 Query: 466 HFQRHKEKYP 475 H H + P Sbjct: 466 HEMIHTGEKP 475 Score = 53.1 bits (126), Expect = 2e-06 Identities = 21/57 (36%), Positives = 33/57 (57%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S + H RSHTGE+P++C CG F+ +++ H +H P+ Sbjct: 196 YKCKVCGKAFDYPSRFRTHERSHTGEKPYECQECGKAFTCITSVRRHMIKHTGDGPY 252 Score = 53.1 bits (126), Expect = 2e-06 Identities = 19/57 (33%), Positives = 33/57 (57%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734 P +C C + S+ ++H RTHTG++P+ CK CG+A++ + + + H H P Sbjct: 475 PFECKRCGKAFRSSSSFRLHERTHTGQKPYHCKECGKAYSCRASFQRHMLTHAEDGP 531 Score = 51.2 bits (121), Expect = 6e-06 Identities = 20/72 (27%), Positives = 39/72 (54%), Gaps = 3/72 (4%) Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465 + E + E P+ +C+ C + F +++ H+ HTGE P+KC +CG F + ++ Sbjct: 353 IHERTHTGEKPY---ECKECGEAFSCIPSMRRHMIKHTGEGPYKCKVCGKPFHSLSPFRI 409 Query: 466 HFQRHKEKYPHI 477 H + H + P++ Sbjct: 410 HERTHTGEKPYV 421 Score = 51.2 bits (121), Expect = 6e-06 Identities = 21/74 (28%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462 ++ + E + E P+ +C+ C K F ++ + H HTGE+PF+C CG F + + Sbjct: 434 SIRIHERTHTGEKPY---ECKQCGKAFSYLNSFRTHEMIHTGEKPFECKRCGKAFRSSSS 490 Query: 463 LKVHFQRHKEKYPH 476 ++H + H + P+ Sbjct: 491 FRLHERTHTGQKPY 504 Score = 50.1 bits (118), Expect = 1e-05 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 3/75 (4%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P E + E P+ +C+ C K F ++++ H+ HTG+ P+KC +CG F + Sbjct: 208 PSRFRTHERSHTGEKPY---ECQECGKAFTCITSVRRHMIKHTGDGPYKCKVCGKPFHSL 264 Query: 461 GNLKVHFQRHKEKYP 475 + +VH + H + P Sbjct: 265 SSFQVHERIHTGEKP 279 Score = 48.1 bits (113), Expect = 5e-05 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 4/80 (5%) Query: 684 CHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPI 743 C + S + + H HTGE+ + CK CG+ F + ++ H H P + C + Sbjct: 145 CWKPFSSHHSFRTHEIIHTGEKLYDCKECGKTFFSLKRIRRHIITHSGYTP----YKCKV 200 Query: 744 CQKKFTNAVVLQQHIRMHMG 763 C K F + H R H G Sbjct: 201 CGKAFDYPSRFRTHERSHTG 220 Score = 46.6 bits (109), Expect = 2e-04 Identities = 17/57 (29%), Positives = 30/57 (52%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 + C+ C K F S ++ H+ +H+G P+KC +CG F + H + H + P+ Sbjct: 168 YDCKECGKTFFSLKRIRRHIITHSGYTPYKCKVCGKAFDYPSRFRTHERSHTGEKPY 224 Score = 38.1 bits (87), Expect = 0.055 Identities = 26/107 (24%), Positives = 47/107 (43%), Gaps = 16/107 (14%) Query: 669 ENIDKKMTDPNQC--VICHRVLSCQSALKMHYRTHTG----------ERPFKCKICGRAF 716 +N+ KK+ C ++ V QS+L H + H+G E+P C + F Sbjct: 90 QNLSKKIPGVKLCESIVYGEVSMGQSSLNRHIKDHSGHEPKEYQEYGEKPDTRNQCWKPF 149 Query: 717 TTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 ++ + +TH +H + + C C K F + +++HI H G Sbjct: 150 SSHHSFRTHEIIHTGEK----LYDCKECGKTFFSLKRIRRHIITHSG 192 Score = 35.4 bits (80), Expect = 0.36 Identities = 16/52 (30%), Positives = 24/52 (46%) Query: 425 CAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 C K F S + + H HTGE+ + C CG F + ++ H H P+ Sbjct: 145 CWKPFSSHHSFRTHEIIHTGEKLYDCKECGKTFFSLKRIRRHIITHSGYTPY 196 >gi|21687252 zinc finger protein 296 [Homo sapiens] Length = 475 Score = 96.3 bits (238), Expect = 2e-19 Identities = 67/213 (31%), Positives = 88/213 (41%), Gaps = 31/213 (14%) Query: 976 STVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQ 1035 S C VC K + S L++H RSHT ERP+ C C C+ L +H THR S Sbjct: 230 SPTCPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPYACAQSSKLNRHKKTHRQVPPQSP 289 Query: 1036 LFDPNFALGPSQSTPS-LISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQT-- 1092 L S + P + +AAPT G G G AGVQ P P + Sbjct: 290 LMADTSQEQASAAPPEPAVHAAAPTSTLPCSGGE------GAGAAATAGVQEPGAPGSGA 343 Query: 1093 VMGPG--------------LAPMLAPPPRRTPKQ--------HNCQSCGKTFSSASALQI 1130 GPG A P++ PK +C+ CGK F+++S L + Sbjct: 344 QAGPGGDTWGAITTEQRTDPANSQKASPKKMPKSGGKSRGPGGSCEFCGKHFTNSSNLTV 403 Query: 1131 HERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 H R+HTGE+P+ C C A L H H Sbjct: 404 HRRSHTGERPYTCEFCNYACAQSSKLNRHRRMH 436 Score = 63.5 bits (153), Expect = 1e-09 Identities = 96/413 (23%), Positives = 138/413 (33%), Gaps = 43/413 (10%) Query: 89 PPPEDFPEPSPASSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPP 148 P P+ P+ +P P E AG G E P PM A A PR P Sbjct: 36 PEPDAQPQQAPRLGPFSPKE---VSSAGRFGGEPHHSP-----GPMPAGAALLALGPRNP 87 Query: 149 PAAPAPPTPAYG--APSTNVTLEALLSTKV-------AVAQFSQ----GARAAGGSGAGG 195 P TP Y P T+ + L + A+ F G + G G Sbjct: 88 WTLWTPLTPNYPDRQPWTDKHPDLLTCGRCLQTFPLEAITAFMDHKKLGCQLFRGPSRGQ 147 Query: 196 GVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAP 255 G + + Q +L Q +++ Q P +P + A Sbjct: 148 GSEREELKALSCLRCGKQFTVAWKLLRHAQWDHGLSIYQTESEAPE-APLLGLAEVAAAV 206 Query: 256 SQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAAPS 315 S + G AA S A + + P P + S + + G + P Sbjct: 207 SAVVGPAAEAKSPRASGSGLTRRSPTCPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPY 266 Query: 316 AAPAPAA---------PAPAPAPQSAASSQPQSASTPP-----ALAPGSLLGAAPGLPSP 361 A + P +P A +SQ Q+++ PP A AP S L + G + Sbjct: 267 ACAQSSKLNRHKKTHRQVPPQSPLMADTSQEQASAAPPEPAVHAAAPTSTLPCSGGEGAG 326 Query: 362 LLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKH- 420 + +GV P S A D A+ ++ P N PK + Sbjct: 327 A---AATAGVQEPGAPGSGAQAGPGGDTWGAITTEQRTDPANSQKASPKKMPKSGGKSRG 383 Query: 421 ---KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 C FC K F + S L +H RSHTGERP+ C C + L H + H Sbjct: 384 PGGSCEFCGKHFTNSSNLTVHRRSHTGERPYTCEFCNYACAQSSKLNRHRRMH 436 Score = 59.7 bits (143), Expect = 2e-08 Identities = 45/172 (26%), Positives = 68/172 (39%), Gaps = 15/172 (8%) Query: 591 PPLTKAEPVS-LPCTNARAGDAPV--GAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQF 647 P + A P S LPC+ A G Q AP S GA G A++ + + Sbjct: 306 PAVHAAAPTSTLPCSGGEGAGAAATAGVQEPGAPGS--GAQAGPGGDTWGAITTEQRTD- 362 Query: 648 PFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPF 707 S+ + +++ ++ K C C + + S L +H R+HTGERP+ Sbjct: 363 --------PANSQKASPKKMPKSGGKSRGPGGSCEFCGKHFTNSSNLTVHRRSHTGERPY 414 Query: 708 KCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIR 759 C+ C A L H +H P + CP C F L +H+R Sbjct: 415 TCEFCNYACAQSSKLNRHRRMH-GMTPGSTRFECPHCHVPFGLRATLDKHLR 465 Score = 55.5 bits (132), Expect = 3e-07 Identities = 42/158 (26%), Positives = 58/158 (36%), Gaps = 32/158 (20%) Query: 893 SPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAA--------A 944 SP ++++S QA + P P + A +P AA A Sbjct: 288 SPLMADTSQEQASAAPPE---------PAVHAAAPTSTLPCSGGEGAGAAATAGVQEPGA 338 Query: 945 PGSGGAPGRAGI---------------KEEAPFSLLFLSRERGKCPSTVCGVCGKPFACK 989 PGSG G G ++A + S + + P C CGK F Sbjct: 339 PGSGAQAGPGGDTWGAITTEQRTDPANSQKASPKKMPKSGGKSRGPGGSCEFCGKHFTNS 398 Query: 990 SALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 S L +H RSHT ERP+ C C C+ L +H H Sbjct: 399 SNLTVHRRSHTGERPYTCEFCNYACAQSSKLNRHRRMH 436 Score = 54.7 bits (130), Expect = 6e-07 Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 8/90 (8%) Query: 1079 PLPAGVQVPAGPQTVMGPGLAPMLAPPPRR-----TPKQHNCQSCGKTFSSASALQIHER 1133 PL +V A V+GP A PR T + C C KT SS S L++H R Sbjct: 195 PLLGLAEVAAAVSAVVGPAAE---AKSPRASGSGLTRRSPTCPVCKKTLSSFSNLKVHMR 251 Query: 1134 THTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 +HTGE+P+ C C A L H TH Sbjct: 252 SHTGERPYACDQCPYACAQSSKLNRHKKTH 281 Score = 53.9 bits (128), Expect = 1e-06 Identities = 24/54 (44%), Positives = 29/54 (53%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734 C +C + LS S LK+H R+HTGERP+ C C A L H HR PP Sbjct: 233 CPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPYACAQSSKLNRHKKTHRQVPP 286 Score = 52.8 bits (125), Expect = 2e-06 Identities = 42/145 (28%), Positives = 61/145 (42%), Gaps = 8/145 (5%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNP 481 C C K S S L++H+RSHTGERP+ C+ C + L H + H++ P + Sbjct: 233 CPVCKKTLSSFSNLKVHMRSHTGERPYACDQCPYACAQSSKLNRHKKTHRQVPPQSPLMA 292 Query: 482 YPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYA 541 E S P ++ P +T S + G+Q P PG+ A Sbjct: 293 DTSQE------QASAAPPEPAVHAAAPTSTLPCSGGEGAGAAATAGVQ-EPGAPGSGAQA 345 Query: 542 DSPSAT-PASRSPQRPSPASSECAS 565 T A + QR PA+S+ AS Sbjct: 346 GPGGDTWGAITTEQRTDPANSQKAS 370 Score = 38.9 bits (89), Expect = 0.032 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 10/81 (12%) Query: 709 CKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMH------M 762 C+ CG+ FT NL H H + P ++C C + L +H RMH Sbjct: 388 CEFCGKHFTNSSNLTVHRRSHTGERP----YTCEFCNYACAQSSKLNRHRRMHGMTPGST 443 Query: 763 GGQIPNTPLPEGFQDAMDSEL 783 + P+ +P G + +D L Sbjct: 444 RFECPHCHVPFGLRATLDKHL 464 >gi|193083160 zinc finger protein 441 [Homo sapiens] Length = 693 Score = 94.4 bits (233), Expect = 7e-19 Identities = 62/188 (32%), Positives = 85/188 (45%), Gaps = 24/188 (12%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F C + L+IH R HT ERP+ C C + + ++ H TH E P + Sbjct: 421 CKQCGKAFICCTYLQIHERIHTGERPYKCKQCGKAFRSSNYIRVHEKTHT-GEKPYECKQ 479 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 AL S + S MI +G K G+ P+ + T P Sbjct: 480 CGKAL-------SHLKSFQRHMIMHTGDGPHKCKICGKSFDSPSSFRRHERIHTGERP-- 530 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 + C+ CGK F S+S +Q+HERTHTGEKP+GC CG+A + + + Sbjct: 531 --------------YKCKLCGKGFRSSSYIQLHERTHTGEKPYGCQQCGKALSDLSSFRR 576 Query: 1159 HMGTHMWN 1166 HM TH N Sbjct: 577 HMITHTGN 584 Score = 94.4 bits (233), Expect = 7e-19 Identities = 64/185 (34%), Positives = 80/185 (43%), Gaps = 24/185 (12%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C +CGK F S+ H R HT ERP+ C LC +G + ++ H TH E P Sbjct: 505 CKICGKSFDSPSSFRRHERIHTGERPYKCKLCGKGFRSSSYIQLHERTHT-GEKPYGCQQ 563 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 AL S +SS MI NG K G+G P+ VQ T Sbjct: 564 CGKAL-------SDLSSFRRHMITHTGNGPHKCKICGKGFDYPSSVQRHERTHT------ 610 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 K + C+ CGK FS +S L+IHER HTGEKP+ C CG+ F Sbjct: 611 ----------GEKPYECKECGKAFSHSSYLRIHERVHTGEKPYKCKECGKPFHCPSAFHK 660 Query: 1159 HMGTH 1163 H TH Sbjct: 661 HERTH 665 Score = 85.1 bits (209), Expect = 4e-16 Identities = 53/189 (28%), Positives = 81/189 (42%), Gaps = 33/189 (17%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C +CGK F S++ H R+HT E+P+ C C + S ++H++TH Sbjct: 310 CKICGKGFLSPSSVRRHKRTHTGEKPYECKYCGKAFSDCTGFRRHMITHT---------- 359 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 GP + + +P++ + H GE P + G Sbjct: 360 ---GDGPHKCKVCGKAFDSPSLCRRHETTH-----TGEKPY-----------KCECGKAF 400 Query: 1099 APMLAPPPRRTP----KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKG 1154 + T K + C+ CGK F + LQIHER HTGE+P+ C CG+AF + Sbjct: 401 SDFYYFRNHETTHTGEKPYKCKQCGKAFICCTYLQIHERIHTGERPYKCKQCGKAFRSSN 460 Query: 1155 NLKVHMGTH 1163 ++VH TH Sbjct: 461 YIRVHEKTH 469 Score = 70.9 bits (172), Expect = 8e-12 Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P QC C + SC +++ RTHTGE+ ++CK CG+AF G+ + H VH P Sbjct: 251 PYQCKQCGKAFSCSCYTQLYERTHTGEQSYECKQCGKAFYHLGSFQRHMIVHTGDGP--- 307 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 H C IC K F + +++H R H G Sbjct: 308 -HKCKICGKGFLSPSSVRRHKRTHTG 332 Score = 70.1 bits (170), Expect = 1e-11 Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 4/100 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P++C IC + S+++ H RTHTGE+P++CK CG+AF+ + H H P Sbjct: 307 PHKCKICGKGFLSPSSVRRHKRTHTGEKPYECKYCGKAFSDCTGFRRHMITHTGDGP--- 363 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQD 777 H C +C K F + + ++H H G + + F D Sbjct: 364 -HKCKVCGKAFDSPSLCRRHETTHTGEKPYKCECGKAFSD 402 Score = 69.7 bits (169), Expect = 2e-11 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + C + L++H R HTGERP+KCK CG+AF + ++ H H + P Sbjct: 418 PYKCKQCGKAFICCTYLQIHERIHTGERPYKCKQCGKAFRSSNYIRVHEKTHTGEKP--- 474 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K ++ Q+H+ MH G Sbjct: 475 -YECKQCGKALSHLKSFQRHMIMHTG 499 Score = 69.3 bits (168), Expect = 2e-11 Identities = 62/212 (29%), Positives = 82/212 (38%), Gaps = 30/212 (14%) Query: 957 KEEAPFSLL-----FLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCR 1011 KE A FS L ++ G P +C +CG F S + R+HT+E+P+ C Sbjct: 172 KECASFSSLENLQRHMAAHHGDGPR-ICKLCGNAFIWPSLFHMLRRTHTEEKPYEYEQCS 230 Query: 1012 RGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKA 1071 + +H TH E P Q A S T L E GKA Sbjct: 231 TAFPAYSSTLRHERTHS-GEKPYQCKQCGKAFSCSCYT-QLYERTHTGEQSYECKQCGKA 288 Query: 1072 MALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIH 1131 V GP H C+ CGK F S S+++ H Sbjct: 289 FYHLGSFQRHMIVHTGDGP----------------------HKCKICGKGFLSPSSVRRH 326 Query: 1132 ERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 +RTHTGEKP+ C CG+AF+ + HM TH Sbjct: 327 KRTHTGEKPYECKYCGKAFSDCTGFRRHMITH 358 Score = 67.8 bits (164), Expect = 7e-11 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 24/110 (21%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P++C IC + S+ + H R HTGERP+KCK+CG+ F + ++ H H + P Sbjct: 502 PHKCKICGKSFDSPSSFRRHERIHTGERPYKCKLCGKGFRSSSYIQLHERTHTGEKPYGC 561 Query: 738 Q------------------------HSCPICQKKFTNAVVLQQHIRMHMG 763 Q H C IC K F +Q+H R H G Sbjct: 562 QQCGKALSDLSSFRRHMITHTGNGPHKCKICGKGFDYPSSVQRHERTHTG 611 Score = 67.0 bits (162), Expect = 1e-10 Identities = 31/84 (36%), Positives = 46/84 (54%), Gaps = 4/84 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P++C IC + S+++ H RTHTGE+P++CK CG+AF+ L+ H VH + P Sbjct: 586 PHKCKICGKGFDYPSSVQRHERTHTGEKPYECKECGKAFSHSSYLRIHERVHTGEKP--- 642 Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761 + C C K F +H R H Sbjct: 643 -YKCKECGKPFHCPSAFHKHERTH 665 Score = 65.9 bits (159), Expect = 2e-10 Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + +++H +THTGE+P++CK CG+A + + + H +H P Sbjct: 446 PYKCKQCGKAFRSSNYIRVHEKTHTGEKPYECKQCGKALSHLKSFQRHMIMHTGDGP--- 502 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 H C IC K F + ++H R+H G Sbjct: 503 -HKCKICGKSFDSPSSFRRHERIHTG 527 Score = 65.1 bits (157), Expect = 4e-10 Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + LS + + H HTG+ P KCKICG++F + + + H +H + P Sbjct: 474 PYECKQCGKALSHLKSFQRHMIMHTGDGPHKCKICGKSFDSPSSFRRHERIHTGERP--- 530 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C +C K F ++ +Q H R H G Sbjct: 531 -YKCKLCGKGFRSSSYIQLHERTHTG 555 Score = 63.5 bits (153), Expect = 1e-09 Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + LS S+ + H THTG P KCKICG+ F +++ H H + P Sbjct: 558 PYGCQQCGKALSDLSSFRRHMITHTGNGPHKCKICGKGFDYPSSVQRHERTHTGEKP--- 614 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+++ L+ H R+H G Sbjct: 615 -YECKECGKAFSHSSYLRIHERVHTG 639 Score = 62.0 bits (149), Expect = 4e-09 Identities = 24/57 (42%), Positives = 36/57 (63%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 HKC+ C K F S S+ + H R HTGERP+KC +CG F + +++H + H + P+ Sbjct: 503 HKCKICGKSFDSPSSFRRHERIHTGERPYKCKLCGKGFRSSSYIQLHERTHTGEKPY 559 Score = 60.1 bits (144), Expect = 1e-08 Identities = 24/57 (42%), Positives = 36/57 (63%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 HKC+ C K F S++Q H R+HTGE+P++C CG FS L++H + H + P+ Sbjct: 587 HKCKICGKGFDYPSSVQRHERTHTGEKPYECKECGKAFSHSSYLRIHERVHTGEKPY 643 Score = 59.7 bits (143), Expect = 2e-08 Identities = 48/184 (26%), Positives = 69/184 (37%), Gaps = 28/184 (15%) Query: 982 CGKPFACKSALEIHYRSHTKERPFVCALCRR--GCSTMGNLKQHLLTHRLKELPSQLFDP 1039 C F S+ H R+H+ E+P+ C C + CS L + T Q Sbjct: 229 CSTAFPAYSSTLRHERTHSGEKPYQCKQCGKAFSCSCYTQLYERTHTGEQSYECKQCGKA 288 Query: 1040 NFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLA 1099 + LG Q MI +G K G+G P+ V+ T Sbjct: 289 FYHLGSFQR----------HMIVHTGDGPHKCKICGKGFLSPSSVRRHKRTHT------- 331 Query: 1100 PMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVH 1159 K + C+ CGK FS + + H THTG+ P C +CG+AF + + H Sbjct: 332 ---------GEKPYECKYCGKAFSDCTGFRRHMITHTGDGPHKCKVCGKAFDSPSLCRRH 382 Query: 1160 MGTH 1163 TH Sbjct: 383 ETTH 386 Score = 58.9 bits (141), Expect = 3e-08 Identities = 25/57 (43%), Positives = 35/57 (61%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F + LQIH R HTGERP+KC CG F + ++VH + H + P+ Sbjct: 419 YKCKQCGKAFICCTYLQIHERIHTGERPYKCKQCGKAFRSSNYIRVHEKTHTGEKPY 475 Score = 57.8 bits (138), Expect = 7e-08 Identities = 24/57 (42%), Positives = 33/57 (57%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 HKC+ C K F S S+++ H R+HTGE+P++C CG FS + H H PH Sbjct: 308 HKCKICGKGFLSPSSVRRHKRTHTGEKPYECKYCGKAFSDCTGFRRHMITHTGDGPH 364 Score = 56.6 bits (135), Expect = 2e-07 Identities = 23/57 (40%), Positives = 32/57 (56%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S S +Q+H R+HTGE+P+ C CG S + + H H PH Sbjct: 531 YKCKLCGKGFRSSSYIQLHERTHTGEKPYGCQQCGKALSDLSSFRRHMITHTGNGPH 587 Score = 55.8 bits (133), Expect = 3e-07 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 4/84 (4%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 +C C + + + H HTG+ P KCKICG+ F + +++ H H + P + Sbjct: 281 ECKQCGKAFYHLGSFQRHMIVHTGDGPHKCKICGKGFLSPSSVRRHKRTHTGEKP----Y 336 Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763 C C K F++ ++H+ H G Sbjct: 337 ECKYCGKAFSDCTGFRRHMITHTG 360 Score = 55.8 bits (133), Expect = 3e-07 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 5/86 (5%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S + H THTGE+P+KCK CG+AF L+ H +H + P Sbjct: 391 PYKCE-CGKAFSDFYYFRNHETTHTGEKPYKCKQCGKAFICCTYLQIHERIHTGERP--- 446 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F ++ ++ H + H G Sbjct: 447 -YKCKQCGKAFRSSNYIRVHEKTHTG 471 Score = 55.5 bits (132), Expect = 3e-07 Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P +V E + E P+ +C+ C K F S L+IH R HTGE+P+KC CG F Sbjct: 599 PSSVQRHERTHTGEKPY---ECKECGKAFSHSSYLRIHERVHTGEKPYKCKECGKPFHCP 655 Query: 461 GNLKVHFQRHKEKYPH 476 H + H + P+ Sbjct: 656 SAFHKHERTHSMEKPY 671 Score = 54.7 bits (130), Expect = 6e-07 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 4/84 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S S L++H R HTGE+P+KCK CG+ F H H + P Sbjct: 614 PYECKECGKAFSHSSYLRIHERVHTGEKPYKCKECGKPFHCPSAFHKHERTHSMEKP--- 670 Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761 + C C + F +H H Sbjct: 671 -YKCKECGEAFHCISSFHKHEMTH 693 Score = 52.4 bits (124), Expect = 3e-06 Identities = 20/57 (35%), Positives = 33/57 (57%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S + +++H ++HTGE+P++C CG S + + H H PH Sbjct: 447 YKCKQCGKAFRSSNYIRVHEKTHTGEKPYECKQCGKALSHLKSFQRHMIMHTGDGPH 503 Score = 50.1 bits (118), Expect = 1e-05 Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 HKC+ C K F S S + H +HTGE+P+KC CG FS + H H + P+ Sbjct: 364 HKCKVCGKAFDSPSLCRRHETTHTGEKPYKCE-CGKAFSDFYYFRNHETTHTGEKPY 419 Score = 48.9 bits (115), Expect = 3e-05 Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 5/115 (4%) Query: 652 LLDSMQTSETSKLQQLVENIDKKMTD-PNQCVICHRVLSCQSALKMHYRTHTGERPFKCK 710 L D + + S L+ L ++ D P C +C S M RTHT E+P++ + Sbjct: 168 LYDCKECASFSSLENLQRHMAAHHGDGPRICKLCGNAFIWPSLFHMLRRTHTEEKPYEYE 227 Query: 711 ICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQ 765 C AF + H H + P + C C K F+ + Q + R H G Q Sbjct: 228 QCSTAFPAYSSTLRHERTHSGEKP----YQCKQCGKAFSCSCYTQLYERTHTGEQ 278 Score = 48.9 bits (115), Expect = 3e-05 Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P +V + + E P+ +C++C K F + + H+ +HTG+ P KC +CG F + Sbjct: 320 PSSVRRHKRTHTGEKPY---ECKYCGKAFSDCTGFRRHMITHTGDGPHKCKVCGKAFDSP 376 Query: 461 GNLKVHFQRHKEKYPH 476 + H H + P+ Sbjct: 377 SLCRRHETTHTGEKPY 392 Score = 48.5 bits (114), Expect = 4e-05 Identities = 19/49 (38%), Positives = 27/49 (55%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 C CGKPF C SA H R+H+ E+P+ C C + + +H +TH Sbjct: 645 CKECGKPFHCPSAFHKHERTHSMEKPYKCKECGEAFHCISSFHKHEMTH 693 Score = 48.1 bits (113), Expect = 5e-05 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 3/73 (4%) Query: 404 VSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNL 463 + V E + E P+ +C+ C K + Q H+ HTG+ P KC ICG F + + Sbjct: 462 IRVHEKTHTGEKPY---ECKQCGKALSHLKSFQRHMIMHTGDGPHKCKICGKSFDSPSSF 518 Query: 464 KVHFQRHKEKYPH 476 + H + H + P+ Sbjct: 519 RRHERIHTGERPY 531 Score = 47.4 bits (111), Expect = 9e-05 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 3/65 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 S E P+ +C+ C K F Q++ R+HTGE+ ++C CG F G+ + H H Sbjct: 247 SGEKPY---QCKQCGKAFSCSCYTQLYERTHTGEQSYECKQCGKAFYHLGSFQRHMIVHT 303 Query: 472 EKYPH 476 PH Sbjct: 304 GDGPH 308 Score = 47.0 bits (110), Expect = 1e-04 Identities = 19/57 (33%), Positives = 32/57 (56%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F + Q H+ HTG+ P KC ICG F + +++ H + H + P+ Sbjct: 280 YECKQCGKAFYHLGSFQRHMIVHTGDGPHKCKICGKGFLSPSSVRRHKRTHTGEKPY 336 Score = 44.7 bits (104), Expect = 6e-04 Identities = 19/51 (37%), Positives = 26/51 (50%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 +KC+ C K F SA H R+H+ E+P+KC CG F + H H Sbjct: 643 YKCKECGKPFHCPSAFHKHERTHSMEKPYKCKECGEAFHCISSFHKHEMTH 693 Score = 43.5 bits (101), Expect = 0.001 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC C K F + H +HTGE+P+KC CG F L++H + H + P+ Sbjct: 392 YKCE-CGKAFSDFYYFRNHETTHTGEKPYKCKQCGKAFICCTYLQIHERIHTGERPY 447 Score = 41.6 bits (96), Expect = 0.005 Identities = 19/53 (35%), Positives = 27/53 (50%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKE 1031 C CGK F+ S L IH R HT E+P+ C C + +H TH +++ Sbjct: 617 CKECGKAFSHSSYLRIHERVHTGEKPYKCKECGKPFHCPSAFHKHERTHSMEK 669 Score = 40.4 bits (93), Expect = 0.011 Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 K + CG FS QIHER G+K + C C +F++ NL+ HM H Sbjct: 139 KPYTHTQCGTAFSYQPCFQIHERPQHGKKLYDCKECA-SFSSLENLQRHMAAH 190 Score = 38.5 bits (88), Expect = 0.042 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Query: 1106 PRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAF 1150 P+ K ++C+ C +FSS LQ H H G+ P C +CG AF Sbjct: 162 PQHGKKLYDCKECA-SFSSLENLQRHMAAHHGDGPRICKLCGNAF 205 Score = 37.7 bits (86), Expect = 0.072 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 1/57 (1%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 + C+ CA F S LQ H+ +H G+ P C +CGN F + + H E+ P+ Sbjct: 169 YDCKECAS-FSSLENLQRHMAAHHGDGPRICKLCGNAFIWPSLFHMLRRTHTEEKPY 224 Score = 37.7 bits (86), Expect = 0.072 Identities = 15/46 (32%), Positives = 27/46 (58%) Query: 425 CAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 C+ F + S+ H R+H+GE+P++C CG FS +++ + H Sbjct: 229 CSTAFPAYSSTLRHERTHSGEKPYQCKQCGKAFSCSCYTQLYERTH 274 Score = 34.7 bits (78), Expect = 0.61 Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 5/65 (7%) Query: 684 CHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPI 743 C S Q ++H R G++ + CK C +F++ NL+ H H P C + Sbjct: 146 CGTAFSYQPCFQIHERPQHGKKLYDCKECA-SFSSLENLQRHMAAHHGDGP----RICKL 200 Query: 744 CQKKF 748 C F Sbjct: 201 CGNAF 205 Score = 32.3 bits (72), Expect = 3.0 Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 1/53 (1%) Query: 425 CAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 C F QIH R G++ + C C + FS+ NL+ H H P I Sbjct: 146 CGTAFSYQPCFQIHERPQHGKKLYDCKECAS-FSSLENLQRHMAAHHGDGPRI 197 Score = 32.3 bits (72), Expect = 3.0 Identities = 14/55 (25%), Positives = 24/55 (43%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 C+ C F S + R+HT E+P++ C F + H + H + P+ Sbjct: 198 CKLCGNAFIWPSLFHMLRRTHTEEKPYEYEQCSTAFPAYSSTLRHERTHSGEKPY 252 >gi|47271376 zinc finger protein 615 [Homo sapiens] Length = 731 Score = 94.4 bits (233), Expect = 7e-19 Identities = 63/186 (33%), Positives = 84/186 (45%), Gaps = 26/186 (13%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK FA KS L H R+HT E+P+VC CR+G + +L H TH E P D Sbjct: 430 CNECGKGFALKSPLIRHQRTHTGEKPYVCTECRKGFTMKSDLIVHQRTHTA-EKPYICND 488 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGE-GPPLPAGVQVPAGPQTVMGPG 1097 G + S + ++ + K GE G PA +++ +T G Sbjct: 489 ----CGKGFTVKSRL------IVHQRTHTGEKPYVCGECGKGFPAKIRLMGHQRTHTGE- 537 Query: 1098 LAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLK 1157 K + C CGK F+ S L +H RTHTGEKP+ C+ CG+ T K L Sbjct: 538 -------------KPYICNECGKGFTEKSHLNVHRRTHTGEKPYVCSECGKDLTGKSMLI 584 Query: 1158 VHMGTH 1163 H TH Sbjct: 585 AHQRTH 590 Score = 88.2 bits (217), Expect = 5e-17 Identities = 60/187 (32%), Positives = 74/187 (39%), Gaps = 54/187 (28%) Query: 978 VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH-RLKELPSQL 1036 VC CGK F S H R HT E+P VC++C + S L H TH LK Sbjct: 205 VCSECGKAFLKLSQFIDHQRVHTGEKPHVCSMCGKAFSRKSRLMDHQRTHTELKHYECTE 264 Query: 1037 FDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP 1096 D F + K ++N H K T MG Sbjct: 265 CDKTF------------------LKKSQLNIHQK---------------------THMGG 285 Query: 1097 GLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNL 1156 K + C CGK F L H+RTHTGEKP GC++CG+AF+TK +L Sbjct: 286 --------------KPYTCSQCGKAFIKKCRLIYHQRTHTGEKPHGCSVCGKAFSTKFSL 331 Query: 1157 KVHMGTH 1163 H TH Sbjct: 332 TTHQKTH 338 Score = 87.8 bits (216), Expect = 6e-17 Identities = 61/188 (32%), Positives = 82/188 (43%), Gaps = 28/188 (14%) Query: 978 VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037 +C CGK F K L H+R+HT E+PF+C C +G + LK L+TH+ +L+ Sbjct: 345 ICSECGKGFIEKRRLTAHHRTHTGEKPFICNKCGKGFT----LKNSLITHQQTHTGEKLY 400 Query: 1038 D-PNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095 G S ++ T K + N GK AL PL + G Sbjct: 401 TCSECGKGFSMKHCLMVHQRTHTGEKPYKCNECGKGFALKS--PLIRHQRTHTG------ 452 Query: 1096 PGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGN 1155 K + C C K F+ S L +H+RTHT EKP+ C CG+ FT K Sbjct: 453 --------------EKPYVCTECRKGFTMKSDLIVHQRTHTAEKPYICNDCGKGFTVKSR 498 Query: 1156 LKVHMGTH 1163 L VH TH Sbjct: 499 LIVHQRTH 506 Score = 84.7 bits (208), Expect = 5e-16 Identities = 58/186 (31%), Positives = 77/186 (41%), Gaps = 26/186 (13%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037 C VCGK F+ K +L H ++HT E+P++C+ C +G L H TH K Sbjct: 318 CSVCGKAFSTKFSLTTHQKTHTGEKPYICSECGKGFIEKRRLTAHHRTHTGEKPFICNKC 377 Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097 F L S T + E G+G + + V T Sbjct: 378 GKGFTLKNSLITHQQTHTGEKLYTCSEC---------GKGFSMKHCLMVHQRTHT----- 423 Query: 1098 LAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLK 1157 K + C CGK F+ S L H+RTHTGEKP+ CT C + FT K +L Sbjct: 424 -----------GEKPYKCNECGKGFALKSPLIRHQRTHTGEKPYVCTECRKGFTMKSDLI 472 Query: 1158 VHMGTH 1163 VH TH Sbjct: 473 VHQRTH 478 Score = 80.1 bits (196), Expect = 1e-14 Identities = 57/188 (30%), Positives = 79/188 (42%), Gaps = 28/188 (14%) Query: 978 VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037 +C CGK F KS L +H R+HT E+P+VC C +G L H TH Sbjct: 485 ICNDCGKGFTVKSRLIVHQRTHTGEKPYVCGECGKGFPAKIRLMGHQRTH---------- 534 Query: 1038 DPNFALGPSQSTPSLISSAAPTMI-KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP 1096 + P + + K +N H + GE P + + G Sbjct: 535 --------TGEKPYICNECGKGFTEKSHLNVHRRTHT-GEKPYVCS----ECGKDLT--- 578 Query: 1097 GLAPMLAPPPRRT-PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGN 1155 G + ++A T K + C CGK F+ S L IH++THTGEKP+ C C + F K Sbjct: 579 GKSMLIAHQRTHTGEKPYICNECGKGFTMKSTLSIHQQTHTGEKPYKCNECDKTFRKKTC 638 Query: 1156 LKVHMGTH 1163 L H H Sbjct: 639 LIQHQRFH 646 Score = 72.8 bits (177), Expect = 2e-12 Identities = 57/214 (26%), Positives = 78/214 (36%), Gaps = 52/214 (24%) Query: 978 VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLF 1037 VCG CGK F K L H R+HT E+P++C C +G + +L H TH Sbjct: 513 VCGECGKGFPAKIRLMGHQRTHTGEKPYICNECGKGFTEKSHLNVHRRTH---------- 562 Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097 + P + S + + + GE P + G M Sbjct: 563 --------TGEKPYVCSECGKDLTGKSMLIAHQRTHTGEKPYICN----ECGKGFTMKST 610 Query: 1098 LAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHT--------------------- 1136 L+ + K + C C KTF + L H+R HT Sbjct: 611 LS--IHQQTHTGEKPYKCNECDKTFRKKTCLIQHQRFHTGKTSFACTECGKFSLRKNDLI 668 Query: 1137 -------GEKPFGCTICGRAFTTKGNLKVHMGTH 1163 GEKP+ C+ CG+AFTTK L VH H Sbjct: 669 THQRIHTGEKPYKCSDCGKAFTTKSGLNVHQRKH 702 Score = 67.4 bits (163), Expect = 9e-11 Identities = 34/86 (39%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + L+ +S L H RTHTGE+P+ C CG+ FT K L H H + P Sbjct: 567 PYVCSECGKDLTGKSMLIAHQRTHTGEKPYICNECGKGFTMKSTLSIHQQTHTGEKP--- 623 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F L QH R H G Sbjct: 624 -YKCNECDKTFRKKTCLIQHQRFHTG 648 Score = 65.1 bits (157), Expect = 4e-10 Identities = 31/81 (38%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740 C C + ++ L H R HTGE+P+KC CG+AFTTK L H H + P + Sbjct: 654 CTECGKFSLRKNDLITHQRIHTGEKPYKCSDCGKAFTTKSGLNVHQRKHTGERP----YG 709 Query: 741 CPICQKKFTNAVVLQQHIRMH 761 C C K F + +L +H R+H Sbjct: 710 CSDCGKAFAHLSILVKHRRIH 730 Score = 63.5 bits (153), Expect = 1e-09 Identities = 33/86 (38%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + + L H RTHTGE+P C +CG+AF+TK +L TH H + P Sbjct: 287 PYTCSQCGKAFIKKCRLIYHQRTHTGEKPHGCSVCGKAFSTKFSLTTHQKTHTGEKP--- 343 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F L H R H G Sbjct: 344 -YICSECGKGFIEKRRLTAHHRTHTG 368 Score = 61.6 bits (148), Expect = 5e-09 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + + +S L +H RTHT E+P+ C CG+ FT K L H H + P Sbjct: 455 PYVCTECRKGFTMKSDLIVHQRTHTAEKPYICNDCGKGFTVKSRLIVHQRTHTGEKP--- 511 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F + L H R H G Sbjct: 512 -YVCGECGKGFPAKIRLMGHQRTHTG 536 Score = 61.6 bits (148), Expect = 5e-09 Identities = 24/53 (45%), Positives = 33/53 (62%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 K + C CGK F++ S L +H+R HTGE+P+GC+ CG+AF L H H Sbjct: 678 KPYKCSDCGKAFTTKSGLNVHQRKHTGERPYGCSDCGKAFAHLSILVKHRRIH 730 Score = 61.2 bits (147), Expect = 6e-09 Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 4/89 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P+ C +C + S + +L H +THTGE+P+ C CG+ F K L H H + P Sbjct: 315 PHGCSVCGKAFSTKFSLTTHQKTHTGEKPYICSECGKGFIEKRRLTAHHRTHTGEKPF-- 372 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQI 766 C C K FT L H + H G ++ Sbjct: 373 --ICNKCGKGFTLKNSLITHQQTHTGEKL 399 Score = 60.8 bits (146), Expect = 8e-09 Identities = 38/125 (30%), Positives = 54/125 (43%), Gaps = 9/125 (7%) Query: 641 EQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRT 700 +QF + F + + S+ K QQ NI+ + + C C + S H R Sbjct: 171 KQFYTEMKFPAIAKPINKSQFIK-QQRTHNIE----NAHVCSECGKAFLKLSQFIDHQRV 225 Query: 701 HTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRM 760 HTGE+P C +CG+AF+ K L H H + C C K F L H + Sbjct: 226 HTGEKPHVCSMCGKAFSRKSRLMDHQRTHTELK----HYECTECDKTFLKKSQLNIHQKT 281 Query: 761 HMGGQ 765 HMGG+ Sbjct: 282 HMGGK 286 Score = 60.8 bits (146), Expect = 8e-09 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 4/84 (4%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 +C C + +S L +H +TH G +P+ C CG+AF K L H H + P H Sbjct: 261 ECTECDKTFLKKSQLNIHQKTHMGGKPYTCSQCGKAFIKKCRLIYHQRTHTGEKP----H 316 Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763 C +C K F+ L H + H G Sbjct: 317 GCSVCGKAFSTKFSLTTHQKTHTG 340 Score = 60.5 bits (145), Expect = 1e-08 Identities = 31/81 (38%), Positives = 40/81 (49%), Gaps = 4/81 (4%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740 C C + S + L +H RTHTGE+P+KC CG+ F K L H H + P + Sbjct: 402 CSECGKGFSMKHCLMVHQRTHTGEKPYKCNECGKGFALKSPLIRHQRTHTGEKP----YV 457 Query: 741 CPICQKKFTNAVVLQQHIRMH 761 C C+K FT L H R H Sbjct: 458 CTECRKGFTMKSDLIVHQRTH 478 Score = 60.5 bits (145), Expect = 1e-08 Identities = 31/86 (36%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + + L H RTHTGE+P+ C CG+ FT K +L H H + P Sbjct: 511 PYVCGECGKGFPAKIRLMGHQRTHTGEKPYICNECGKGFTEKSHLNVHRRTHTGEKP--- 567 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K T +L H R H G Sbjct: 568 -YVCSECGKDLTGKSMLIAHQRTHTG 592 Score = 60.1 bits (144), Expect = 1e-08 Identities = 33/86 (38%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + +S L H RTHTGE+P+ C C + FT K +L H H A+ P Sbjct: 427 PYKCNECGKGFALKSPLIRHQRTHTGEKPYVCTECRKGFTMKSDLIVHQRTHTAEKP--- 483 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K FT L H R H G Sbjct: 484 -YICNDCGKGFTVKSRLIVHQRTHTG 508 Score = 59.7 bits (143), Expect = 2e-08 Identities = 25/51 (49%), Positives = 30/51 (58%) Query: 1113 HNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 H C CGK F S H+R HTGEKP C++CG+AF+ K L H TH Sbjct: 204 HVCSECGKAFLKLSQFIDHQRVHTGEKPHVCSMCGKAFSRKSRLMDHQRTH 254 Score = 59.7 bits (143), Expect = 2e-08 Identities = 35/103 (33%), Positives = 45/103 (43%), Gaps = 4/103 (3%) Query: 661 TSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720 T K +V P C C + + +S L +H RTHTGE+P+ C CG+ F K Sbjct: 466 TMKSDLIVHQRTHTAEKPYICNDCGKGFTVKSRLIVHQRTHTGEKPYVCGECGKGFPAKI 525 Query: 721 NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 L H H + P + C C K FT L H R H G Sbjct: 526 RLMGHQRTHTGEKP----YICNECGKGFTEKSHLNVHRRTHTG 564 Score = 59.3 bits (142), Expect = 2e-08 Identities = 26/54 (48%), Positives = 30/54 (55%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHM 1164 K H C CGK FS S L H+RTHT K + CT C + F K L +H THM Sbjct: 230 KPHVCSMCGKAFSRKSRLMDHQRTHTELKHYECTECDKTFLKKSQLNIHQKTHM 283 Score = 56.6 bits (135), Expect = 2e-07 Identities = 31/86 (36%), Positives = 41/86 (47%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + + +S L +H RTHTGE+P+ C CG+ T K L H H + P Sbjct: 539 PYICNECGKGFTEKSHLNVHRRTHTGEKPYVCSECGKDLTGKSMLIAHQRTHTGEKP--- 595 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K FT L H + H G Sbjct: 596 -YICNECGKGFTMKSTLSIHQQTHTG 620 Score = 55.8 bits (133), Expect = 3e-07 Identities = 23/58 (39%), Positives = 33/58 (56%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 + C C K F L +H R+HTGE+P+KCN CG F+ K L H + H + P++ Sbjct: 400 YTCSECGKGFSMKHCLMVHQRTHTGEKPYKCNECGKGFALKSPLIRHQRTHTGEKPYV 457 Score = 55.1 bits (131), Expect = 4e-07 Identities = 24/58 (41%), Positives = 33/58 (56%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 + C C K F L H R+HTGE+P C++CG FSTK +L H + H + P+I Sbjct: 288 YTCSQCGKAFIKKCRLIYHQRTHTGEKPHGCSVCGKAFSTKFSLTTHQKTHTGEKPYI 345 Score = 55.1 bits (131), Expect = 4e-07 Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + ++ L H R HTG+ F C CG+ K +L TH +H + P Sbjct: 623 PYKCNECDKTFRKKTCLIQHQRFHTGKTSFACTECGKFSLRKNDLITHQRIHTGEKP--- 679 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K FT L H R H G Sbjct: 680 -YKCSDCGKAFTTKSGLNVHQRKHTG 704 Score = 53.5 bits (127), Expect = 1e-06 Identities = 23/56 (41%), Positives = 33/56 (58%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 C C K F + L H R+HTGE+P+ CN CG F+ K +L VH + H + P++ Sbjct: 514 CGECGKGFPAKIRLMGHQRTHTGEKPYICNECGKGFTEKSHLNVHRRTHTGEKPYV 569 Score = 53.5 bits (127), Expect = 1e-06 Identities = 26/74 (35%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462 +++V + E P+ C C K S L H R+HTGE+P+ CN CG F+ K Sbjct: 554 HLNVHRRTHTGEKPYV---CSECGKDLTGKSMLIAHQRTHTGEKPYICNECGKGFTMKST 610 Query: 463 LKVHFQRHKEKYPH 476 L +H Q H + P+ Sbjct: 611 LSIHQQTHTGEKPY 624 Score = 53.1 bits (126), Expect = 2e-06 Identities = 22/58 (37%), Positives = 31/58 (53%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 H C C K F + +L H ++HTGE+P+ C+ CG F K L H + H + P I Sbjct: 316 HGCSVCGKAFSTKFSLTTHQKTHTGEKPYICSECGKGFIEKRRLTAHHRTHTGEKPFI 373 Score = 53.1 bits (126), Expect = 2e-06 Identities = 23/55 (41%), Positives = 32/55 (58%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 C C K + L H R HTGE+P+KC+ CG F+TK L VH ++H + P+ Sbjct: 654 CTECGKFSLRKNDLITHQRIHTGEKPYKCSDCGKAFTTKSGLNVHQRKHTGERPY 708 Score = 52.8 bits (125), Expect = 2e-06 Identities = 24/58 (41%), Positives = 33/58 (56%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 +KC C K F S L H R+HTGE+P+ C C F+ K +L VH + H + P+I Sbjct: 428 YKCNECGKGFALKSPLIRHQRTHTGEKPYVCTECRKGFTMKSDLIVHQRTHTAEKPYI 485 Score = 52.8 bits (125), Expect = 2e-06 Identities = 23/56 (41%), Positives = 32/56 (57%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 C C K F S L +H R+HT E+P+ CN CG F+ K L VH + H + P++ Sbjct: 458 CTECRKGFTMKSDLIVHQRTHTAEKPYICNDCGKGFTVKSRLIVHQRTHTGEKPYV 513 Score = 52.4 bits (124), Expect = 3e-06 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P+ C +C + S +S L H RTHT + ++C C + F K L H H P Sbjct: 231 PHVCSMCGKAFSRKSRLMDHQRTHTELKHYECTECDKTFLKKSQLNIHQKTHMGGKP--- 287 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 ++C C K F L H R H G Sbjct: 288 -YTCSQCGKAFIKKCRLIYHQRTHTG 312 Score = 52.4 bits (124), Expect = 3e-06 Identities = 35/110 (31%), Positives = 50/110 (45%), Gaps = 6/110 (5%) Query: 370 GVIFPNPLVSIAATANALDPLSALMKHRKG--KPPNVSVFEPKASAEDPFFKHKCRFCAK 427 G +PL+ T P + RKG ++ V + +AE P+ C C K Sbjct: 436 GFALKSPLIRHQRTHTGEKPY-VCTECRKGFTMKSDLIVHQRTHTAEKPYI---CNDCGK 491 Query: 428 VFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 F S L +H R+HTGE+P+ C CG F K L H + H + P+I Sbjct: 492 GFTVKSRLIVHQRTHTGEKPYVCGECGKGFPAKIRLMGHQRTHTGEKPYI 541 Score = 52.0 bits (123), Expect = 4e-06 Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + + +++L H +THTGE+ + C CG+ F+ K L H H + P Sbjct: 371 PFICNKCGKGFTLKNSLITHQQTHTGEKLYTCSECGKGFSMKHCLMVHQRTHTGEKP--- 427 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F L +H R H G Sbjct: 428 -YKCNECGKGFALKSPLIRHQRTHTG 452 Score = 52.0 bits (123), Expect = 4e-06 Identities = 22/53 (41%), Positives = 30/53 (56%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHR 730 P +C C + + +S L +H R HTGERP+ C CG+AF L H +HR Sbjct: 679 PYKCSDCGKAFTTKSGLNVHQRKHTGERPYGCSDCGKAFAHLSILVKHRRIHR 731 Score = 52.0 bits (123), Expect = 4e-06 Identities = 22/52 (42%), Positives = 30/52 (57%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 +KC C K F + S L +H R HTGERP+ C+ CG F+ L H + H+ Sbjct: 680 YKCSDCGKAFTTKSGLNVHQRKHTGERPYGCSDCGKAFAHLSILVKHRRIHR 731 Score = 51.6 bits (122), Expect = 5e-06 Identities = 28/73 (38%), Positives = 34/73 (46%) Query: 400 KPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFST 459 KP N S F + + H C C K F S H R HTGE+P C++CG FS Sbjct: 184 KPINKSQFIKQQRTHNIENAHVCSECGKAFLKLSQFIDHQRVHTGEKPHVCSMCGKAFSR 243 Query: 460 KGNLKVHFQRHKE 472 K L H + H E Sbjct: 244 KSRLMDHQRTHTE 256 Score = 51.6 bits (122), Expect = 5e-06 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 5/82 (6%) Query: 398 KGKPPNVSVF--EPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGN 455 KG P + + + + E P+ C C K F S L +H R+HTGE+P+ C+ CG Sbjct: 519 KGFPAKIRLMGHQRTHTGEKPYI---CNECGKGFTEKSHLNVHRRTHTGEKPYVCSECGK 575 Query: 456 RFSTKGNLKVHFQRHKEKYPHI 477 + K L H + H + P+I Sbjct: 576 DLTGKSMLIAHQRTHTGEKPYI 597 Score = 51.6 bits (122), Expect = 5e-06 Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + + +S L +H +THTGE+P+KC C + F K L H H K Sbjct: 595 PYICNECGKGFTMKSTLSIHQQTHTGEKPYKCNECDKTFRKKTCLIQHQRFHTGK----T 650 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 +C C K L H R+H G Sbjct: 651 SFACTECGKFSLRKNDLITHQRIHTG 676 Score = 50.8 bits (120), Expect = 8e-06 Identities = 25/59 (42%), Positives = 31/59 (52%), Gaps = 3/59 (5%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 + E P+ C C K F L H R+HTGE+PF CN CG F+ K +L H Q H Sbjct: 339 TGEKPYI---CSECGKGFIEKRRLTAHHRTHTGEKPFICNKCGKGFTLKNSLITHQQTH 394 Score = 49.3 bits (116), Expect = 2e-05 Identities = 25/62 (40%), Positives = 32/62 (51%), Gaps = 3/62 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + E P+ C C K F S L IH ++HTGE+P+KCN C F K L H + H Sbjct: 591 TGEKPYI---CNECGKGFTMKSTLSIHQQTHTGEKPYKCNECDKTFRKKTCLIQHQRFHT 647 Query: 472 EK 473 K Sbjct: 648 GK 649 Score = 49.3 bits (116), Expect = 2e-05 Identities = 21/50 (42%), Positives = 28/50 (56%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR 1028 C CGK F KS L +H R HT ERP+ C+ C + + + L +H HR Sbjct: 682 CSDCGKAFTTKSGLNVHQRKHTGERPYGCSDCGKAFAHLSILVKHRRIHR 731 Score = 48.1 bits (113), Expect = 5e-05 Identities = 21/57 (36%), Positives = 30/57 (52%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C C K F S L IH ++H G +P+ C+ CG F K L H + H + PH Sbjct: 260 YECTECDKTFLKKSQLNIHQKTHMGGKPYTCSQCGKAFIKKCRLIYHQRTHTGEKPH 316 Score = 47.4 bits (111), Expect = 9e-05 Identities = 24/65 (36%), Positives = 35/65 (53%), Gaps = 3/65 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + E PF C C K F ++L H ++HTGE+ + C+ CG FS K L VH + H Sbjct: 367 TGEKPFI---CNKCGKGFTLKNSLITHQQTHTGEKLYTCSECGKGFSMKHCLMVHQRTHT 423 Query: 472 EKYPH 476 + P+ Sbjct: 424 GEKPY 428 Score = 44.3 bits (103), Expect = 8e-04 Identities = 19/57 (33%), Positives = 26/57 (45%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 H C C K F S L H R+HT + ++C C F K L +H + H P+ Sbjct: 232 HVCSMCGKAFSRKSRLMDHQRTHTELKHYECTECDKTFLKKSQLNIHQKTHMGGKPY 288 Score = 38.5 bits (88), Expect = 0.042 Identities = 19/52 (36%), Positives = 25/52 (48%) Query: 976 STVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 S C CGK K+ L H R HT E+P+ C+ C + +T L H H Sbjct: 651 SFACTECGKFSLRKNDLITHQRIHTGEKPYKCSDCGKAFTTKSGLNVHQRKH 702 >gi|224548994 zinc finger protein 709 isoform b [Homo sapiens] Length = 609 Score = 94.0 bits (232), Expect = 8e-19 Identities = 60/194 (30%), Positives = 88/194 (45%), Gaps = 14/194 (7%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+C S+ +H R+HT E+P C C + S +++ H TH E P + Sbjct: 362 CKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRIHERTHT-GEKPYECKQ 420 Query: 1039 PNFALGPSQST---PSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095 A S S + + P E GKA + + P Sbjct: 421 CGKAFSCSSSFRMHERIHTGEKP----YECKQCGKAFSFSSSFRMHERTHTGEKPYECKQ 476 Query: 1096 PGLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149 G A + R + H C+ CGK FS +S+++IHERTHTGEKP+ C CG+A Sbjct: 477 CGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKA 536 Query: 1150 FTTKGNLKVHMGTH 1163 F+ ++++H TH Sbjct: 537 FSCSSSVRMHERTH 550 Score = 89.7 bits (221), Expect = 2e-17 Identities = 55/185 (29%), Positives = 81/185 (43%), Gaps = 24/185 (12%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK +C ++ H R HT E+P+ C C + S + ++H H E P + Sbjct: 250 CKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHT-GEKPYDCKE 308 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 A + S MI NG K G+ P+ Q+ T Sbjct: 309 CGKAF-------ISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHT------ 355 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 K + C+ CGK FS +S+ ++HERTHTGEKP C CG+AF+ ++++ Sbjct: 356 ----------GEKPYECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRI 405 Query: 1159 HMGTH 1163 H TH Sbjct: 406 HERTH 410 Score = 87.8 bits (216), Expect = 6e-17 Identities = 60/192 (31%), Positives = 88/192 (45%), Gaps = 10/192 (5%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+C S++ IH R+HT E+P+ C C + S + + H H E P + Sbjct: 390 CKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHT-GEKPYECKQ 448 Query: 1039 PNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097 A S S+ + T K E GKA + + P G Sbjct: 449 CGKAF--SFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCG 506 Query: 1098 LAPMLAPPPR---RT---PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151 A + R RT K + C+ CGK FS +S++++HERTHTG KP+ C C +AF+ Sbjct: 507 KAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFS 566 Query: 1152 TKGNLKVHMGTH 1163 + ++H TH Sbjct: 567 CSRSFRIHERTH 578 Score = 87.8 bits (216), Expect = 6e-17 Identities = 58/192 (30%), Positives = 81/192 (42%), Gaps = 10/192 (5%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+C S+ +H R HT E+P+ C C + S + + H TH E P + Sbjct: 418 CKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHT-GEKPYECKQ 476 Query: 1039 PNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097 A S S + T K E GKA + + P G Sbjct: 477 CGKAFSCSSSFR--MHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCG 534 Query: 1098 LAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151 A + R + H C+ C K FS + + +IHERTHTGEKP+ C CG+AF Sbjct: 535 KAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRSFRIHERTHTGEKPYACQQCGKAFK 594 Query: 1152 TKGNLKVHMGTH 1163 + ++H H Sbjct: 595 CSRSFRIHERVH 606 Score = 85.1 bits (209), Expect = 4e-16 Identities = 61/194 (31%), Positives = 82/194 (42%), Gaps = 14/194 (7%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+ S+ H R+H+ E+P+ C C + + H TH E P Q Sbjct: 194 CKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTH-TGEKPYQCKQ 252 Query: 1039 PNFALGPSQSTPS---LISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095 AL S S + + P K GKA + + P Sbjct: 253 CGKALSCPTSFRSHERIHTGEKPYKCKK----CGKAFSFPSSFRKHERIHTGEKPYDCKE 308 Query: 1096 PGLAPMLAPPPRRTPKQH------NCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149 G A + P RR H C+ CGK F S+ QIHERTHTGEKP+ C CG+A Sbjct: 309 CGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKA 368 Query: 1150 FTTKGNLKVHMGTH 1163 F+ + ++H TH Sbjct: 369 FSCSSSFRMHERTH 382 Score = 78.6 bits (192), Expect = 4e-14 Identities = 59/198 (29%), Positives = 85/198 (42%), Gaps = 16/198 (8%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+ S+ +IH R+HT E+P+ C C + + H+ H E P + + Sbjct: 138 CKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRGHMRMHT-GEKPYKCKE 196 Query: 1039 PNFALGPSQSTPSLISSAAPTMI---KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095 G + S PS + T E GKA + + P Sbjct: 197 ----CGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQ 252 Query: 1096 PGLAPMLAPPPRRT-------PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGR 1148 G A + P R+ K + C+ CGK FS S+ + HER HTGEKP+ C CG+ Sbjct: 253 CGKA-LSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGK 311 Query: 1149 AFTTKGNLKVHMGTHMWN 1166 AF + + + HM H N Sbjct: 312 AFISLPSYRRHMIMHTGN 329 Score = 75.9 bits (185), Expect = 2e-13 Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P++C C + SC S++++H RTHTGE+P++CK CG+AF+ + + H +H + P Sbjct: 387 PHECKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHTGEKP--- 443 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + + H R H G Sbjct: 444 -YECKQCGKAFSFSSSFRMHERTHTG 468 Score = 75.9 bits (185), Expect = 2e-13 Identities = 32/86 (37%), Positives = 50/86 (58%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S+ +MH RTHTGE+P++CK CG+AF+ +++ H H + P Sbjct: 471 PYECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKP--- 527 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + ++ H R H G Sbjct: 528 -YECKQCGKAFSCSSSVRMHERTHTG 552 Score = 74.3 bits (181), Expect = 7e-13 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S+ +MH RTHTGE+P +CK CG+AF+ +++ H H + P Sbjct: 359 PYECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRIHERTHTGEKP--- 415 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + + H R+H G Sbjct: 416 -YECKQCGKAFSCSSSFRMHERIHTG 440 Score = 73.9 bits (180), Expect = 9e-13 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P QC C + LSC ++ + H R HTGE+P+KCK CG+AF+ + + H +H + P Sbjct: 247 PYQCKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGEKP--- 303 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F + ++H+ MH G Sbjct: 304 -YDCKECGKAFISLPSYRRHMIMHTG 328 Score = 72.8 bits (177), Expect = 2e-12 Identities = 55/191 (28%), Positives = 78/191 (40%), Gaps = 36/191 (18%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+ +S+ IH R+HT E+P+ C C + S + + H TH E P + + Sbjct: 110 CKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTH-TGEKPYECKE 168 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 A + GH + M GE P + +T P Sbjct: 169 CGKAF----------------IYHTTFRGHMR-MHTGEKP-----YKCKECGKTFSHPSS 206 Query: 1099 APMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTT 1152 R + H+ C+ CGK F QIHERTHTGEKP+ C CG+A + Sbjct: 207 F-------RNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSC 259 Query: 1153 KGNLKVHMGTH 1163 + + H H Sbjct: 260 PTSFRSHERIH 270 Score = 72.4 bits (176), Expect = 3e-12 Identities = 55/201 (27%), Positives = 76/201 (37%), Gaps = 46/201 (22%) Query: 979 CGVCGKPFACKSALEIHYRSHTK----------ERPFVCALCRRGCSTMGNLKQHLLTHR 1028 C VCGK + C S+L H RSHT+ E+ + C C + S + + H TH Sbjct: 72 CSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHERTH- 130 Query: 1029 LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPA 1088 + P K GKA + + Sbjct: 131 -------------------------TGEKPYKCKQ----CGKAFSWPSSFQIHERTHTGE 161 Query: 1089 GPQTVMGPGLAPMLAPPPRRTPKQH------NCQSCGKTFSSASALQIHERTHTGEKPFG 1142 P G A + R + H C+ CGKTFS S+ + HERTH+GEKP+ Sbjct: 162 KPYECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHPSSFRNHERTHSGEKPYE 221 Query: 1143 CTICGRAFTTKGNLKVHMGTH 1163 C CG+AF ++H TH Sbjct: 222 CKQCGKAFRYYQTFQIHERTH 242 Score = 72.4 bits (176), Expect = 3e-12 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S++++H RTHTGE+P++CK CG+AF+ +++ H H P Sbjct: 499 PYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKP--- 555 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + + H R H G Sbjct: 556 -YECKQCDKAFSCSRSFRIHERTHTG 580 Score = 72.0 bits (175), Expect = 3e-12 Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + C S+ ++H RTHTGE+P++CK CG+AF+ + + H H + P Sbjct: 331 PYKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKP--- 387 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 H C C K F+ + ++ H R H G Sbjct: 388 -HECKQCGKAFSCSSSVRIHERTHTG 412 Score = 72.0 bits (175), Expect = 3e-12 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S+ +MH R HTGE+P++CK CG+AF+ + + H H + P Sbjct: 415 PYECKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHTGEKP--- 471 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + + H R H G Sbjct: 472 -YECKQCGKAFSCSSSFRMHERTHTG 496 Score = 70.1 bits (170), Expect = 1e-11 Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S S+ +MH RTHTGE+P++CK CG+AF+ + + H H + P Sbjct: 443 PYECKQCGKAFSFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKP--- 499 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + ++ H R H G Sbjct: 500 -YECKQCGKAFSCSSSIRIHERTHTG 524 Score = 69.7 bits (169), Expect = 2e-11 Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 4/84 (4%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 +C C + S +S+ ++H RTHTGE+P+KCK CG+AF+ + + H H + P + Sbjct: 109 ECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTHTGEKP----Y 164 Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763 C C K F + H+RMH G Sbjct: 165 ECKECGKAFIYHTTFRGHMRMHTG 188 Score = 67.8 bits (164), Expect = 7e-11 Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S+++MH RTHTG +P++CK C +AF+ + + H H + P Sbjct: 527 PYECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRSFRIHERTHTGEKP--- 583 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 ++C C K F + + H R+H G Sbjct: 584 -YACQQCGKAFKCSRSFRIHERVHSG 608 Score = 67.0 bits (162), Expect = 1e-10 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S S+ ++H RTHTGE+P++CK CG+AF + H +H + P Sbjct: 135 PYKCKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRGHMRMHTGEKP--- 191 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F++ + H R H G Sbjct: 192 -YKCKECGKTFSHPSSFRNHERTHSG 216 Score = 63.2 bits (152), Expect = 2e-09 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + ++H RTHTGE+P++CK CG+A + + ++H +H + P Sbjct: 219 PYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSCPTSFRSHERIHTGEKP--- 275 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ ++H R+H G Sbjct: 276 -YKCKKCGKAFSFPSSFRKHERIHTG 300 Score = 62.8 bits (151), Expect = 2e-09 Identities = 24/57 (42%), Positives = 36/57 (63%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S+ QIH R+HTGE+P++C CG FS + ++H + H + PH Sbjct: 332 YKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPH 388 Score = 61.2 bits (147), Expect = 6e-09 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S S+ + H R HTGE+P+ CK CG+AF + + + H +H P Sbjct: 275 PYKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGKAFISLPSYRRHMIMHTGNGP--- 331 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F Q H R H G Sbjct: 332 -YKCKECGKAFDCPSSFQIHERTHTG 356 Score = 60.8 bits (146), Expect = 8e-09 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + + H R HTGE+P+KCK CG+ F+ + + H H + P Sbjct: 163 PYECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHPSSFRNHERTHSGEKP--- 219 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F Q H R H G Sbjct: 220 -YECKQCGKAFRYYQTFQIHERTHTG 244 Score = 60.1 bits (144), Expect = 1e-08 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S S+ + H RTH+GE+P++CK CG+AF + H H + P Sbjct: 191 PYKCKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKP--- 247 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K + + H R+H G Sbjct: 248 -YQCKQCGKALSCPTSFRSHERIHTG 272 Score = 60.1 bits (144), Expect = 1e-08 Identities = 22/57 (38%), Positives = 37/57 (64%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 H+C+ C K F S+++IH R+HTGE+P++C CG FS + ++H + H + P+ Sbjct: 388 HECKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHTGEKPY 444 Score = 59.3 bits (142), Expect = 2e-08 Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P + + E + E P+ +C+ C K F S+ ++H R+HTGE+P +C CG FS Sbjct: 344 PSSFQIHERTHTGEKPY---ECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCS 400 Query: 461 GNLKVHFQRHKEKYPH 476 ++++H + H + P+ Sbjct: 401 SSVRIHERTHTGEKPY 416 Score = 58.9 bits (141), Expect = 3e-08 Identities = 50/181 (27%), Positives = 71/181 (39%), Gaps = 30/181 (16%) Query: 962 FSLLFLSRER---GKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMG 1018 FS F ER G+ P C CGK F+C S+ +H R+HT E+P+ C C + S Sbjct: 455 FSSSFRMHERTHTGEKPYE-CKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSS 513 Query: 1019 NLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEG 1077 +++ H TH E P + A S S + T +K E KA + Sbjct: 514 SIRIHERTHT-GEKPYECKQCGKAFSCSSSVR--MHERTHTGVKPYECKQCDKAFSCSRS 570 Query: 1078 PPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTG 1137 + P + CQ CGK F + + +IHER H+G Sbjct: 571 FRIHERTHTGEKP----------------------YACQQCGKAFKCSRSFRIHERVHSG 608 Query: 1138 E 1138 E Sbjct: 609 E 609 Score = 58.5 bits (140), Expect = 4e-08 Identities = 20/57 (35%), Positives = 37/57 (64%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F S+ ++H R+HTGE+P++C CG FS ++++H + H + P+ Sbjct: 472 YECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPY 528 Score = 58.2 bits (139), Expect = 5e-08 Identities = 21/57 (36%), Positives = 37/57 (64%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F S+++IH R+HTGE+P++C CG FS ++++H + H P+ Sbjct: 500 YECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKPY 556 Score = 57.4 bits (137), Expect = 9e-08 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 14/96 (14%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHT----------GERPFKCKICGRAFTTKGNLKTHFG 727 P +C +C + C S+L H R+HT GE+ ++CK CG+ F+ + + + H Sbjct: 69 PYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHER 128 Query: 728 VHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 H + P + C C K F+ Q H R H G Sbjct: 129 THTGEKP----YKCKQCGKAFSWPSSFQIHERTHTG 160 Score = 57.4 bits (137), Expect = 9e-08 Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 3/74 (4%) Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462 +V + E + E P+ +C+ C K F S+ ++H R HTGE+P++C CG FS + Sbjct: 402 SVRIHERTHTGEKPY---ECKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSS 458 Query: 463 LKVHFQRHKEKYPH 476 ++H + H + P+ Sbjct: 459 FRMHERTHTGEKPY 472 Score = 57.0 bits (136), Expect = 1e-07 Identities = 22/57 (38%), Positives = 36/57 (63%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F S+ +IH R+HTGE+P+KC CG FS + ++H + H + P+ Sbjct: 108 YECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTHTGEKPY 164 Score = 56.6 bits (135), Expect = 2e-07 Identities = 20/57 (35%), Positives = 36/57 (63%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F S+ ++H R+HTGE+P++C CG FS + ++H + H + P+ Sbjct: 444 YECKQCGKAFSFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPY 500 Score = 55.8 bits (133), Expect = 3e-07 Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 3/71 (4%) Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465 + E + E P+ KC+ C K F S+ QIH R+HTGE+P++C CG F + Sbjct: 125 IHERTHTGEKPY---KCKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRG 181 Query: 466 HFQRHKEKYPH 476 H + H + P+ Sbjct: 182 HMRMHTGEKPY 192 Score = 54.7 bits (130), Expect = 6e-07 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P + + E + E P+ +C+ C K F + + H+R HTGE+P+KC CG FS Sbjct: 148 PSSFQIHERTHTGEKPY---ECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHP 204 Query: 461 GNLKVHFQRHKEKYPH 476 + + H + H + P+ Sbjct: 205 SSFRNHERTHSGEKPY 220 Score = 53.9 bits (128), Expect = 1e-06 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + + + H HTG P+KCK CG+AF + + H H + P Sbjct: 303 PYDCKECGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKP--- 359 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + + H R H G Sbjct: 360 -YECKQCGKAFSCSSSFRMHERTHTG 384 Score = 53.5 bits (127), Expect = 1e-06 Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 3/74 (4%) Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462 ++ + E + E P+ +C+ C K F S++++H R+HTG +P++C C FS + Sbjct: 514 SIRIHERTHTGEKPY---ECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRS 570 Query: 463 LKVHFQRHKEKYPH 476 ++H + H + P+ Sbjct: 571 FRIHERTHTGEKPY 584 Score = 51.2 bits (121), Expect = 6e-06 Identities = 19/57 (33%), Positives = 33/57 (57%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S+ + H R+H+GE+P++C CG F ++H + H + P+ Sbjct: 192 YKCKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPY 248 Score = 51.2 bits (121), Expect = 6e-06 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P + E S E P+ +C+ C K F QIH R+HTGE+P++C CG S Sbjct: 204 PSSFRNHERTHSGEKPY---ECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSCP 260 Query: 461 GNLKVHFQRHKEKYPH 476 + + H + H + P+ Sbjct: 261 TSFRSHERIHTGEKPY 276 Score = 50.4 bits (119), Expect = 1e-05 Identities = 18/51 (35%), Positives = 30/51 (58%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 ++C+ C K F + +IH R+HTGE+P+ C CG F + ++H + H Sbjct: 556 YECKQCDKAFSCSRSFRIHERTHTGEKPYACQQCGKAFKCSRSFRIHERVH 606 Score = 50.1 bits (118), Expect = 1e-05 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465 + E + E P+ +C+ C K ++ + H R HTGE+P+KC CG FS + + Sbjct: 237 IHERTHTGEKPY---QCKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRK 293 Query: 466 HFQRHKEKYPH 476 H + H + P+ Sbjct: 294 HERIHTGEKPY 304 Score = 48.1 bits (113), Expect = 5e-05 Identities = 20/57 (35%), Positives = 30/57 (52%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S+ + H R HTGE+P+ C CG F + + + H H P+ Sbjct: 276 YKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGKAFISLPSYRRHMIMHTGNGPY 332 Score = 47.8 bits (112), Expect = 7e-05 Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 10/67 (14%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHT----------GERPFKCNICGNRFSTKGNLKVHFQR 469 ++C C K + S+L H+RSHT GE+ ++C CG RFS + + ++H + Sbjct: 70 YECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHERT 129 Query: 470 HKEKYPH 476 H + P+ Sbjct: 130 HTGEKPY 136 Score = 46.2 bits (108), Expect = 2e-04 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 10/63 (15%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHT----------GEKPFGCTICGRAFTTKGNLKVHM 1160 K + C CGK + S+L H R+HT GEK + C CG+ F+ + + ++H Sbjct: 68 KPYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHE 127 Query: 1161 GTH 1163 TH Sbjct: 128 RTH 130 Score = 45.8 bits (107), Expect = 3e-04 Identities = 18/57 (31%), Positives = 30/57 (52%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 + C+ C K F S + + H+ HTG P+KC CG F + ++H + H + P+ Sbjct: 304 YDCKECGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKPY 360 Score = 35.4 bits (80), Expect = 0.36 Identities = 14/45 (31%), Positives = 26/45 (57%) Query: 1119 GKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 G+T S + +++T T KP+ C++CG+ + +L HM +H Sbjct: 48 GETISQTPNPKPNKKTFTRVKPYECSVCGKDYMCHSSLNRHMRSH 92 Score = 35.4 bits (80), Expect = 0.36 Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 6/75 (8%) Query: 695 KMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV------QHSCPICQKKF 748 K + +T T +P++C +CG+ + +L H H + C C K+F Sbjct: 58 KPNKKTFTRVKPYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRF 117 Query: 749 TNAVVLQQHIRMHMG 763 + + H R H G Sbjct: 118 SFRSSFRIHERTHTG 132 >gi|22749235 zinc finger protein 709 isoform a [Homo sapiens] Length = 641 Score = 94.0 bits (232), Expect = 8e-19 Identities = 60/194 (30%), Positives = 88/194 (45%), Gaps = 14/194 (7%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+C S+ +H R+HT E+P C C + S +++ H TH E P + Sbjct: 394 CKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRIHERTHT-GEKPYECKQ 452 Query: 1039 PNFALGPSQST---PSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095 A S S + + P E GKA + + P Sbjct: 453 CGKAFSCSSSFRMHERIHTGEKP----YECKQCGKAFSFSSSFRMHERTHTGEKPYECKQ 508 Query: 1096 PGLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149 G A + R + H C+ CGK FS +S+++IHERTHTGEKP+ C CG+A Sbjct: 509 CGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKA 568 Query: 1150 FTTKGNLKVHMGTH 1163 F+ ++++H TH Sbjct: 569 FSCSSSVRMHERTH 582 Score = 89.7 bits (221), Expect = 2e-17 Identities = 55/185 (29%), Positives = 81/185 (43%), Gaps = 24/185 (12%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK +C ++ H R HT E+P+ C C + S + ++H H E P + Sbjct: 282 CKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHT-GEKPYDCKE 340 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 A + S MI NG K G+ P+ Q+ T Sbjct: 341 CGKAF-------ISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHT------ 387 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 K + C+ CGK FS +S+ ++HERTHTGEKP C CG+AF+ ++++ Sbjct: 388 ----------GEKPYECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRI 437 Query: 1159 HMGTH 1163 H TH Sbjct: 438 HERTH 442 Score = 87.8 bits (216), Expect = 6e-17 Identities = 60/192 (31%), Positives = 88/192 (45%), Gaps = 10/192 (5%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+C S++ IH R+HT E+P+ C C + S + + H H E P + Sbjct: 422 CKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHT-GEKPYECKQ 480 Query: 1039 PNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097 A S S+ + T K E GKA + + P G Sbjct: 481 CGKAF--SFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCG 538 Query: 1098 LAPMLAPPPR---RT---PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151 A + R RT K + C+ CGK FS +S++++HERTHTG KP+ C C +AF+ Sbjct: 539 KAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFS 598 Query: 1152 TKGNLKVHMGTH 1163 + ++H TH Sbjct: 599 CSRSFRIHERTH 610 Score = 87.8 bits (216), Expect = 6e-17 Identities = 58/192 (30%), Positives = 81/192 (42%), Gaps = 10/192 (5%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+C S+ +H R HT E+P+ C C + S + + H TH E P + Sbjct: 450 CKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHT-GEKPYECKQ 508 Query: 1039 PNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPG 1097 A S S + T K E GKA + + P G Sbjct: 509 CGKAFSCSSSFR--MHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCG 566 Query: 1098 LAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151 A + R + H C+ C K FS + + +IHERTHTGEKP+ C CG+AF Sbjct: 567 KAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRSFRIHERTHTGEKPYACQQCGKAFK 626 Query: 1152 TKGNLKVHMGTH 1163 + ++H H Sbjct: 627 CSRSFRIHERVH 638 Score = 85.1 bits (209), Expect = 4e-16 Identities = 61/194 (31%), Positives = 82/194 (42%), Gaps = 14/194 (7%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+ S+ H R+H+ E+P+ C C + + H TH E P Q Sbjct: 226 CKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTH-TGEKPYQCKQ 284 Query: 1039 PNFALGPSQSTPS---LISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095 AL S S + + P K GKA + + P Sbjct: 285 CGKALSCPTSFRSHERIHTGEKPYKCKK----CGKAFSFPSSFRKHERIHTGEKPYDCKE 340 Query: 1096 PGLAPMLAPPPRRTPKQH------NCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149 G A + P RR H C+ CGK F S+ QIHERTHTGEKP+ C CG+A Sbjct: 341 CGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKA 400 Query: 1150 FTTKGNLKVHMGTH 1163 F+ + ++H TH Sbjct: 401 FSCSSSFRMHERTH 414 Score = 78.6 bits (192), Expect = 4e-14 Identities = 59/198 (29%), Positives = 85/198 (42%), Gaps = 16/198 (8%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+ S+ +IH R+HT E+P+ C C + + H+ H E P + + Sbjct: 170 CKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRGHMRMHT-GEKPYKCKE 228 Query: 1039 PNFALGPSQSTPSLISSAAPTMI---KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095 G + S PS + T E GKA + + P Sbjct: 229 ----CGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQ 284 Query: 1096 PGLAPMLAPPPRRT-------PKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGR 1148 G A + P R+ K + C+ CGK FS S+ + HER HTGEKP+ C CG+ Sbjct: 285 CGKA-LSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGK 343 Query: 1149 AFTTKGNLKVHMGTHMWN 1166 AF + + + HM H N Sbjct: 344 AFISLPSYRRHMIMHTGN 361 Score = 75.9 bits (185), Expect = 2e-13 Identities = 31/86 (36%), Positives = 51/86 (59%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P++C C + SC S++++H RTHTGE+P++CK CG+AF+ + + H +H + P Sbjct: 419 PHECKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHTGEKP--- 475 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + + H R H G Sbjct: 476 -YECKQCGKAFSFSSSFRMHERTHTG 500 Score = 75.9 bits (185), Expect = 2e-13 Identities = 32/86 (37%), Positives = 50/86 (58%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S+ +MH RTHTGE+P++CK CG+AF+ +++ H H + P Sbjct: 503 PYECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKP--- 559 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + ++ H R H G Sbjct: 560 -YECKQCGKAFSCSSSVRMHERTHTG 584 Score = 74.3 bits (181), Expect = 7e-13 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S+ +MH RTHTGE+P +CK CG+AF+ +++ H H + P Sbjct: 391 PYECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRIHERTHTGEKP--- 447 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + + H R+H G Sbjct: 448 -YECKQCGKAFSCSSSFRMHERIHTG 472 Score = 73.9 bits (180), Expect = 9e-13 Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P QC C + LSC ++ + H R HTGE+P+KCK CG+AF+ + + H +H + P Sbjct: 279 PYQCKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGEKP--- 335 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F + ++H+ MH G Sbjct: 336 -YDCKECGKAFISLPSYRRHMIMHTG 360 Score = 72.8 bits (177), Expect = 2e-12 Identities = 55/191 (28%), Positives = 78/191 (40%), Gaps = 36/191 (18%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+ +S+ IH R+HT E+P+ C C + S + + H TH E P + + Sbjct: 142 CKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTH-TGEKPYECKE 200 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 A + GH + M GE P + +T P Sbjct: 201 CGKAF----------------IYHTTFRGHMR-MHTGEKP-----YKCKECGKTFSHPSS 238 Query: 1099 APMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTT 1152 R + H+ C+ CGK F QIHERTHTGEKP+ C CG+A + Sbjct: 239 F-------RNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSC 291 Query: 1153 KGNLKVHMGTH 1163 + + H H Sbjct: 292 PTSFRSHERIH 302 Score = 72.4 bits (176), Expect = 3e-12 Identities = 55/201 (27%), Positives = 76/201 (37%), Gaps = 46/201 (22%) Query: 979 CGVCGKPFACKSALEIHYRSHTK----------ERPFVCALCRRGCSTMGNLKQHLLTHR 1028 C VCGK + C S+L H RSHT+ E+ + C C + S + + H TH Sbjct: 104 CSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHERTH- 162 Query: 1029 LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPA 1088 + P K GKA + + Sbjct: 163 -------------------------TGEKPYKCKQ----CGKAFSWPSSFQIHERTHTGE 193 Query: 1089 GPQTVMGPGLAPMLAPPPRRTPKQH------NCQSCGKTFSSASALQIHERTHTGEKPFG 1142 P G A + R + H C+ CGKTFS S+ + HERTH+GEKP+ Sbjct: 194 KPYECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHPSSFRNHERTHSGEKPYE 253 Query: 1143 CTICGRAFTTKGNLKVHMGTH 1163 C CG+AF ++H TH Sbjct: 254 CKQCGKAFRYYQTFQIHERTH 274 Score = 72.4 bits (176), Expect = 3e-12 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S++++H RTHTGE+P++CK CG+AF+ +++ H H P Sbjct: 531 PYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKP--- 587 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + + H R H G Sbjct: 588 -YECKQCDKAFSCSRSFRIHERTHTG 612 Score = 72.0 bits (175), Expect = 3e-12 Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + C S+ ++H RTHTGE+P++CK CG+AF+ + + H H + P Sbjct: 363 PYKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKP--- 419 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 H C C K F+ + ++ H R H G Sbjct: 420 -HECKQCGKAFSCSSSVRIHERTHTG 444 Score = 72.0 bits (175), Expect = 3e-12 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S+ +MH R HTGE+P++CK CG+AF+ + + H H + P Sbjct: 447 PYECKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHTGEKP--- 503 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + + H R H G Sbjct: 504 -YECKQCGKAFSCSSSFRMHERTHTG 528 Score = 70.1 bits (170), Expect = 1e-11 Identities = 31/86 (36%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S S+ +MH RTHTGE+P++CK CG+AF+ + + H H + P Sbjct: 475 PYECKQCGKAFSFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKP--- 531 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + ++ H R H G Sbjct: 532 -YECKQCGKAFSCSSSIRIHERTHTG 556 Score = 69.7 bits (169), Expect = 2e-11 Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 4/84 (4%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 +C C + S +S+ ++H RTHTGE+P+KCK CG+AF+ + + H H + P + Sbjct: 141 ECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTHTGEKP----Y 196 Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763 C C K F + H+RMH G Sbjct: 197 ECKECGKAFIYHTTFRGHMRMHTG 220 Score = 67.8 bits (164), Expect = 7e-11 Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S+++MH RTHTG +P++CK C +AF+ + + H H + P Sbjct: 559 PYECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRSFRIHERTHTGEKP--- 615 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 ++C C K F + + H R+H G Sbjct: 616 -YACQQCGKAFKCSRSFRIHERVHSG 640 Score = 67.0 bits (162), Expect = 1e-10 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S S+ ++H RTHTGE+P++CK CG+AF + H +H + P Sbjct: 167 PYKCKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRGHMRMHTGEKP--- 223 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F++ + H R H G Sbjct: 224 -YKCKECGKTFSHPSSFRNHERTHSG 248 Score = 63.2 bits (152), Expect = 2e-09 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + ++H RTHTGE+P++CK CG+A + + ++H +H + P Sbjct: 251 PYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSCPTSFRSHERIHTGEKP--- 307 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ ++H R+H G Sbjct: 308 -YKCKKCGKAFSFPSSFRKHERIHTG 332 Score = 62.8 bits (151), Expect = 2e-09 Identities = 24/57 (42%), Positives = 36/57 (63%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S+ QIH R+HTGE+P++C CG FS + ++H + H + PH Sbjct: 364 YKCKECGKAFDCPSSFQIHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPH 420 Score = 61.2 bits (147), Expect = 6e-09 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S S+ + H R HTGE+P+ CK CG+AF + + + H +H P Sbjct: 307 PYKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGKAFISLPSYRRHMIMHTGNGP--- 363 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F Q H R H G Sbjct: 364 -YKCKECGKAFDCPSSFQIHERTHTG 388 Score = 60.8 bits (146), Expect = 8e-09 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + + H R HTGE+P+KCK CG+ F+ + + H H + P Sbjct: 195 PYECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHPSSFRNHERTHSGEKP--- 251 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F Q H R H G Sbjct: 252 -YECKQCGKAFRYYQTFQIHERTHTG 276 Score = 60.1 bits (144), Expect = 1e-08 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S S+ + H RTH+GE+P++CK CG+AF + H H + P Sbjct: 223 PYKCKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKP--- 279 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K + + H R+H G Sbjct: 280 -YQCKQCGKALSCPTSFRSHERIHTG 304 Score = 60.1 bits (144), Expect = 1e-08 Identities = 22/57 (38%), Positives = 37/57 (64%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 H+C+ C K F S+++IH R+HTGE+P++C CG FS + ++H + H + P+ Sbjct: 420 HECKQCGKAFSCSSSVRIHERTHTGEKPYECKQCGKAFSCSSSFRMHERIHTGEKPY 476 Score = 59.3 bits (142), Expect = 2e-08 Identities = 24/76 (31%), Positives = 43/76 (56%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P + + E + E P+ +C+ C K F S+ ++H R+HTGE+P +C CG FS Sbjct: 376 PSSFQIHERTHTGEKPY---ECKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCS 432 Query: 461 GNLKVHFQRHKEKYPH 476 ++++H + H + P+ Sbjct: 433 SSVRIHERTHTGEKPY 448 Score = 58.9 bits (141), Expect = 3e-08 Identities = 50/181 (27%), Positives = 71/181 (39%), Gaps = 30/181 (16%) Query: 962 FSLLFLSRER---GKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMG 1018 FS F ER G+ P C CGK F+C S+ +H R+HT E+P+ C C + S Sbjct: 487 FSSSFRMHERTHTGEKPYE-CKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSS 545 Query: 1019 NLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIK-MEVNGHGKAMALGEG 1077 +++ H TH E P + A S S + T +K E KA + Sbjct: 546 SIRIHERTHT-GEKPYECKQCGKAFSCSSSVR--MHERTHTGVKPYECKQCDKAFSCSRS 602 Query: 1078 PPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTG 1137 + P + CQ CGK F + + +IHER H+G Sbjct: 603 FRIHERTHTGEKP----------------------YACQQCGKAFKCSRSFRIHERVHSG 640 Query: 1138 E 1138 E Sbjct: 641 E 641 Score = 58.5 bits (140), Expect = 4e-08 Identities = 20/57 (35%), Positives = 37/57 (64%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F S+ ++H R+HTGE+P++C CG FS ++++H + H + P+ Sbjct: 504 YECKQCGKAFSCSSSFRMHERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPY 560 Score = 58.2 bits (139), Expect = 5e-08 Identities = 21/57 (36%), Positives = 37/57 (64%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F S+++IH R+HTGE+P++C CG FS ++++H + H P+ Sbjct: 532 YECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTHTGVKPY 588 Score = 57.4 bits (137), Expect = 9e-08 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 14/96 (14%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHT----------GERPFKCKICGRAFTTKGNLKTHFG 727 P +C +C + C S+L H R+HT GE+ ++CK CG+ F+ + + + H Sbjct: 101 PYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHER 160 Query: 728 VHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 H + P + C C K F+ Q H R H G Sbjct: 161 THTGEKP----YKCKQCGKAFSWPSSFQIHERTHTG 192 Score = 57.4 bits (137), Expect = 9e-08 Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 3/74 (4%) Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462 +V + E + E P+ +C+ C K F S+ ++H R HTGE+P++C CG FS + Sbjct: 434 SVRIHERTHTGEKPY---ECKQCGKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSS 490 Query: 463 LKVHFQRHKEKYPH 476 ++H + H + P+ Sbjct: 491 FRMHERTHTGEKPY 504 Score = 57.0 bits (136), Expect = 1e-07 Identities = 22/57 (38%), Positives = 36/57 (63%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F S+ +IH R+HTGE+P+KC CG FS + ++H + H + P+ Sbjct: 140 YECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTHTGEKPY 196 Score = 56.6 bits (135), Expect = 2e-07 Identities = 20/57 (35%), Positives = 36/57 (63%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F S+ ++H R+HTGE+P++C CG FS + ++H + H + P+ Sbjct: 476 YECKQCGKAFSFSSSFRMHERTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPY 532 Score = 55.8 bits (133), Expect = 3e-07 Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 3/71 (4%) Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465 + E + E P+ KC+ C K F S+ QIH R+HTGE+P++C CG F + Sbjct: 157 IHERTHTGEKPY---KCKQCGKAFSWPSSFQIHERTHTGEKPYECKECGKAFIYHTTFRG 213 Query: 466 HFQRHKEKYPH 476 H + H + P+ Sbjct: 214 HMRMHTGEKPY 224 Score = 54.7 bits (130), Expect = 6e-07 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P + + E + E P+ +C+ C K F + + H+R HTGE+P+KC CG FS Sbjct: 180 PSSFQIHERTHTGEKPY---ECKECGKAFIYHTTFRGHMRMHTGEKPYKCKECGKTFSHP 236 Query: 461 GNLKVHFQRHKEKYPH 476 + + H + H + P+ Sbjct: 237 SSFRNHERTHSGEKPY 252 Score = 53.9 bits (128), Expect = 1e-06 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + + + H HTG P+KCK CG+AF + + H H + P Sbjct: 335 PYDCKECGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKP--- 391 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + + H R H G Sbjct: 392 -YECKQCGKAFSCSSSFRMHERTHTG 416 Score = 53.5 bits (127), Expect = 1e-06 Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 3/74 (4%) Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462 ++ + E + E P+ +C+ C K F S++++H R+HTG +P++C C FS + Sbjct: 546 SIRIHERTHTGEKPY---ECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRS 602 Query: 463 LKVHFQRHKEKYPH 476 ++H + H + P+ Sbjct: 603 FRIHERTHTGEKPY 616 Score = 51.2 bits (121), Expect = 6e-06 Identities = 19/57 (33%), Positives = 33/57 (57%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S+ + H R+H+GE+P++C CG F ++H + H + P+ Sbjct: 224 YKCKECGKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPY 280 Score = 51.2 bits (121), Expect = 6e-06 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P + E S E P+ +C+ C K F QIH R+HTGE+P++C CG S Sbjct: 236 PSSFRNHERTHSGEKPY---ECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSCP 292 Query: 461 GNLKVHFQRHKEKYPH 476 + + H + H + P+ Sbjct: 293 TSFRSHERIHTGEKPY 308 Score = 50.4 bits (119), Expect = 1e-05 Identities = 18/51 (35%), Positives = 30/51 (58%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 ++C+ C K F + +IH R+HTGE+P+ C CG F + ++H + H Sbjct: 588 YECKQCDKAFSCSRSFRIHERTHTGEKPYACQQCGKAFKCSRSFRIHERVH 638 Score = 50.1 bits (118), Expect = 1e-05 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465 + E + E P+ +C+ C K ++ + H R HTGE+P+KC CG FS + + Sbjct: 269 IHERTHTGEKPY---QCKQCGKALSCPTSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRK 325 Query: 466 HFQRHKEKYPH 476 H + H + P+ Sbjct: 326 HERIHTGEKPY 336 Score = 48.1 bits (113), Expect = 5e-05 Identities = 20/57 (35%), Positives = 30/57 (52%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S+ + H R HTGE+P+ C CG F + + + H H P+ Sbjct: 308 YKCKKCGKAFSFPSSFRKHERIHTGEKPYDCKECGKAFISLPSYRRHMIMHTGNGPY 364 Score = 47.8 bits (112), Expect = 7e-05 Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 10/67 (14%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHT----------GERPFKCNICGNRFSTKGNLKVHFQR 469 ++C C K + S+L H+RSHT GE+ ++C CG RFS + + ++H + Sbjct: 102 YECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHERT 161 Query: 470 HKEKYPH 476 H + P+ Sbjct: 162 HTGEKPY 168 Score = 46.2 bits (108), Expect = 2e-04 Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 10/63 (15%) Query: 1111 KQHNCQSCGKTFSSASALQIHERTHT----------GEKPFGCTICGRAFTTKGNLKVHM 1160 K + C CGK + S+L H R+HT GEK + C CG+ F+ + + ++H Sbjct: 100 KPYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHE 159 Query: 1161 GTH 1163 TH Sbjct: 160 RTH 162 Score = 45.8 bits (107), Expect = 3e-04 Identities = 18/57 (31%), Positives = 30/57 (52%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 + C+ C K F S + + H+ HTG P+KC CG F + ++H + H + P+ Sbjct: 336 YDCKECGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKPY 392 Score = 35.4 bits (80), Expect = 0.36 Identities = 14/45 (31%), Positives = 26/45 (57%) Query: 1119 GKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 G+T S + +++T T KP+ C++CG+ + +L HM +H Sbjct: 80 GETISQTPNPKPNKKTFTRVKPYECSVCGKDYMCHSSLNRHMRSH 124 Score = 35.4 bits (80), Expect = 0.36 Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 6/75 (8%) Query: 695 KMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV------QHSCPICQKKF 748 K + +T T +P++C +CG+ + +L H H + C C K+F Sbjct: 90 KPNKKTFTRVKPYECSVCGKDYMCHSSLNRHMRSHTEHRSYEYHKYGEKSYECKECGKRF 149 Query: 749 TNAVVLQQHIRMHMG 763 + + H R H G Sbjct: 150 SFRSSFRIHERTHTG 164 >gi|40807465 zinc finger protein 341 [Homo sapiens] Length = 847 Score = 93.2 bits (230), Expect = 1e-18 Identities = 98/338 (28%), Positives = 126/338 (37%), Gaps = 69/338 (20%) Query: 142 TRAPRPPPAAPAP----PTPAYGAPSTNVTL--EALLSTKVAVAQFSQGARAAGGSGAGG 195 T + PP AAP PTPA ST +T+ L+ T V G Sbjct: 90 TNSIYPPSAAPTAVQQAPTPANRQISTYITVPPSPLIQTLVQ-----------GNILVSD 138 Query: 196 GVAAAAVPLI--LEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRPSLSPAAAPSAPGP 253 V +A+ L+Q M + + + S + PPP P P P P P Sbjct: 139 DVLMSAMSAFTSLDQPMPQGPPPVQSSLNMHSVPSYLTQPPPPPPPPPPLPPPPPPQPPP 198 Query: 254 APSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESGASTPGGPAEPSAPAA 313 P P S G P G G + A PL+ G+ T A P Sbjct: 199 PP---------PQSLGPPGRPNPG-GNGVVEVYSAAAPLA----GSGTVEIQALGMQPYP 244 Query: 314 PSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIF 373 P P +P TP +PG G P P+P P TSA+G Sbjct: 245 PLEVPNQCV-------------EPPVYPTPTVYSPGKQ-GFKPKGPNPAAPMTSATG--- 287 Query: 374 PNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDS 433 T D A +K R+ K +PKA K KC +C K F + Sbjct: 288 --------GTVATFDS-PATLKTRRAKAAG----KPKAQ------KLKCSYCDKSFTKNF 328 Query: 434 ALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 LQ H+RSHTGE+PF+C CG F+ K N+K H Q HK Sbjct: 329 DLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHK 366 Score = 69.3 bits (168), Expect = 2e-11 Identities = 63/267 (23%), Positives = 98/267 (36%), Gaps = 46/267 (17%) Query: 925 PEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERG------------ 972 P P E+P + P P + +PG+ G K + P ++ G Sbjct: 242 PYPPLEVPNQCVEP--PVYPTPTVYSPGKQGFKPKGPNPAAPMTSATGGTVATFDSPATL 299 Query: 973 -----------KCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLK 1021 K C C K F L+ H RSHT E+PF C C R + N+K Sbjct: 300 KTRRAKAAGKPKAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVK 359 Query: 1022 QHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLP 1081 +H+ TH++ + G S T S +S ++ + + + G G PLP Sbjct: 360 KHMQTHKV-----------WPPGHSGGTVSR-NSVTVQVMALNPSRQEDEESTGLGQPLP 407 Query: 1082 AGVQVPAGPQTVMGPGLAPMLAPPPRRT---PKQHNCQSCGKTFSSASALQIHERTHTGE 1138 Q PQ + G P ++ + CQ C FS+ L+ H H E Sbjct: 408 GAPQ----PQALSTAGEEEGDKPESKQVVLIDSSYLCQFCPSKFSTYFQLKSHMTQHKNE 463 Query: 1139 KPFGCTI--CGRAFTTKGNLKVHMGTH 1163 + + C + C + F H+ +H Sbjct: 464 QVYKCVVKSCAQTFPKLDTFLEHIKSH 490 Score = 68.9 bits (167), Expect = 3e-11 Identities = 73/308 (23%), Positives = 109/308 (35%), Gaps = 55/308 (17%) Query: 479 MNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAH 538 +N + VP YL P PP P P LP P Q PP P + Sbjct: 166 LNMHSVPSYLTQPPP----------PPPPP--------PPLPPPPPP---QPPPPPPQSL 204 Query: 539 GYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEP 598 G P RP+P + G+ V S + A S + + P Sbjct: 205 G------------PPGRPNPGGN-------GVVEVYSAAAPLAGSGTVEIQALGMQPYPP 245 Query: 599 VSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQT 658 + +P + + PV + G +P P S GG + + + Sbjct: 246 LEVP---NQCVEPPVYPTPTVYSPGKQGFKPKGPNPAAPMTSAT-------GGTVATFDS 295 Query: 659 SETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTT 718 T K ++ + K +C C + + L+ H R+HTGE+PF+C CGRAF Sbjct: 296 PATLKTRR-AKAAGKPKAQKLKCSYCDKSFTKNFDLQQHIRSHTGEKPFQCIACGRAFAQ 354 Query: 719 KGNLKTHFGVHRAKPPLR----VQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEG 774 K N+K H H+ PP V + Q N + +G +P P P+ Sbjct: 355 KSNVKKHMQTHKVWPPGHSGGTVSRNSVTVQVMALNPSRQEDEESTGLGQPLPGAPQPQA 414 Query: 775 FQDAMDSE 782 A + E Sbjct: 415 LSTAGEEE 422 Score = 62.0 bits (149), Expect = 4e-09 Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 9/89 (10%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 +C +C + + LK+H H+GE+P+KC +C AF K LK H +H P + ++ Sbjct: 588 KCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHE---PFK-KY 643 Query: 740 SCPI-----CQKKFTNAVVLQQHIRMHMG 763 CP C K+F L+ HI H G Sbjct: 644 KCPFSTHTGCSKEFNRPDKLKAHILSHSG 672 Score = 61.2 bits (147), Expect = 6e-09 Identities = 69/290 (23%), Positives = 105/290 (36%), Gaps = 42/290 (14%) Query: 891 AGSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGA 950 +G S + Q ++ PS E S G P PQ L T A Sbjct: 373 SGGTVSRNSVTVQVMALNPSRQEDEESTGLGQPLPGAPQPQALST--------------A 418 Query: 951 PGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCAL- 1009 G K E+ +L S S +C C F+ L+ H H E+ + C + Sbjct: 419 GEEEGDKPESKQVVLIDS-------SYLCQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVK 471 Query: 1010 -CRRGCSTMGNLKQHLLTHRLK-----ELPSQLFDPNFALGPSQSTPSLISSAAPTMIKM 1063 C + + +H+ +H+ + L + F + LG Q + SL+ +P Sbjct: 472 SCAQTFPKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHSLLPQHSPK---- 527 Query: 1064 EVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRRTPKQH---------- 1113 + N K + P ++ T P P R ++H Sbjct: 528 KDNAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHCQKVFPCERYLRRHLPTHGSGGRF 587 Query: 1114 NCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 CQ C K F L++H H+GEKP+ C++C AF K LK HM H Sbjct: 588 KCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIH 637 Score = 58.5 bits (140), Expect = 4e-08 Identities = 44/181 (24%), Positives = 64/181 (35%), Gaps = 47/181 (25%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C VC K F + L++H H+ E+P+ C++C + LK+H+L H P + + Sbjct: 589 CQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHE----PFKKYK 644 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 F S T P +K + H Sbjct: 645 CPF----STHTGCSKEFNRPDKLKAHILSHSGM--------------------------- 673 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 K H C C K+FS + L H+R HTG F C C + F+ LK Sbjct: 674 ------------KLHKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKD 721 Query: 1159 H 1159 H Sbjct: 722 H 722 Score = 55.5 bits (132), Expect = 3e-07 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 4/81 (4%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740 C C +V C+ L+ H TH FKC++C + F + LK H +H + P + Sbjct: 561 CPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIHSGEKP----YK 616 Query: 741 CPICQKKFTNAVVLQQHIRMH 761 C +C+ F L++H+ +H Sbjct: 617 CSVCESAFNRKDKLKRHMLIH 637 Score = 53.1 bits (126), Expect = 2e-06 Identities = 20/53 (37%), Positives = 33/53 (62%) Query: 419 KHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + KC+ C K F + L++H H+GE+P+KC++C + F+ K LK H H+ Sbjct: 586 RFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKRHMLIHE 638 Score = 50.1 bits (118), Expect = 1e-05 Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 15/94 (15%) Query: 396 HRKGKPPNVSVFEPKASAED----------PFFKHKCRF-----CAKVFGSDSALQIHLR 440 H KP SV E + +D PF K+KC F C+K F L+ H+ Sbjct: 609 HSGEKPYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSTHTGCSKEFNRPDKLKAHIL 668 Query: 441 SHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKY 474 SH+G + KC +C FS + +L H + H Y Sbjct: 669 SHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNY 702 Score = 47.4 bits (111), Expect = 9e-05 Identities = 25/91 (27%), Positives = 35/91 (38%), Gaps = 9/91 (9%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKI-----CGRAFTTKGNLKTHFGVHRAK 732 P +C +C + + LK H H + +KC C + F LK H H Sbjct: 614 PYKCSVCESAFNRKDKLKRHMLIHEPFKKYKCPFSTHTGCSKEFNRPDKLKAHILSHSGM 673 Query: 733 PPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 H C +C K F+ L +H R H G Sbjct: 674 K----LHKCALCSKSFSRRAHLAEHQRAHTG 700 Score = 45.4 bits (106), Expect = 3e-04 Identities = 112/553 (20%), Positives = 168/553 (30%), Gaps = 128/553 (23%) Query: 240 PSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAA---IAGSGPAAPAAFEGAQPLSRPE 296 PS +P A AP PA Q+ +P S I S +A L +P Sbjct: 96 PSAAPTAVQQAPTPANRQISTYITVPPSPLIQTLVQGNILVSDDVLMSAMSAFTSLDQP- 154 Query: 297 SGASTPGGP----------AEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPAL 346 P GP + PS P P P P P P P PQS P Sbjct: 155 ----MPQGPPPVQSSLNMHSVPSYLTQPPPPPPPPPPLPPPPPPQPPPPPPQSLGPPGRP 210 Query: 347 APGS-----LLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKP 401 PG + AA L + A G+ P + ++P + Sbjct: 211 NPGGNGVVEVYSAAAPLAGSGTVEIQALGM---QPYPPLEVPNQCVEP--PVYPTPTVYS 265 Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGE---RPFKCNICGNRFS 458 P F+PK F S + L+ G+ + KC+ C F+ Sbjct: 266 PGKQGFKPKGPNPAAPMTSATGGTVATFDSPATLKTRRAKAAGKPKAQKLKCSYCDKSFT 325 Query: 459 TKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPV 518 +L+ H + H P+ I G + + V + + V Sbjct: 326 KNFDLQQHIRS------HTGEKPFQC------------IACGRAFAQKSNVKKHMQTHKV 367 Query: 519 LPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVS 578 P PG G S ++ PS E S GL Sbjct: 368 WP--------------PGHSGGTVSRNSVTVQVMALNPSRQEDE---ESTGLG------- 403 Query: 579 ATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPA 638 Q L G P +P +L GD P Q + Sbjct: 404 ------QPLPGAP-----QPQALSTAGEEEGDKPESKQ-------------------VVL 433 Query: 639 VSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDK-KMTDPNQCVI--CHRVLSCQSALK 695 + + QF S+ S QL ++ + K +CV+ C + Sbjct: 434 IDSSYLCQFC---------PSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFL 484 Query: 696 MHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS---------CPICQK 746 H ++H E ++C +CG+ F + +L GVH+ L QHS C C Sbjct: 485 EHIKSHQEELSYRCHLCGKDFPSLYDL----GVHQYSHSLLPQHSPKKDNAVYKCVKCVN 540 Query: 747 KFTNAVVLQQHIR 759 K++ L+ H++ Sbjct: 541 KYSTPEALEHHLQ 553 Score = 43.1 bits (100), Expect = 0.002 Identities = 20/47 (42%), Positives = 24/47 (51%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVH 466 HKC C+K F + L H R+HTG F+C C FS LK H Sbjct: 676 HKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKDH 722 Score = 41.6 bits (96), Expect = 0.005 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 5/82 (6%) Query: 684 CHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPI 743 C + + LK H +H+G + KC +C ++F+ + +L H H R C Sbjct: 653 CSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGNYKFR----CAG 708 Query: 744 CQKKFTNAVVLQQHIRMHMGGQ 765 C K F+ L+ H R +G Q Sbjct: 709 CAKGFSRHKYLKDH-RCRLGPQ 729 Score = 40.4 bits (93), Expect = 0.011 Identities = 19/55 (34%), Positives = 27/55 (49%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 C C KVF + L+ HL +H FKC +C F + LK+H H + P+ Sbjct: 561 CPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIHSGEKPY 615 Score = 39.7 bits (91), Expect = 0.019 Identities = 16/47 (34%), Positives = 25/47 (53%) Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTH 725 ++C +C + S ++ L H R HTG F+C C + F+ LK H Sbjct: 676 HKCALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKDH 722 Score = 38.1 bits (87), Expect = 0.055 Identities = 15/49 (30%), Positives = 25/49 (51%) Query: 1118 CGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWN 1166 C K F+ L+ H +H+G K C +C ++F+ + +L H H N Sbjct: 653 CSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAHTGN 701 Score = 37.7 bits (86), Expect = 0.072 Identities = 27/98 (27%), Positives = 38/98 (38%), Gaps = 12/98 (12%) Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHT---------GERPFKCNI 452 P + F + ++C C K F S L +H SH+ +KC Sbjct: 478 PKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHSLLPQHSPKKDNAVYKCVK 537 Query: 453 CGNRFSTKGNLKVHFQ--RHKEKYPHIQMNPYPVPEYL 488 C N++ST L+ H Q H PH Q +P YL Sbjct: 538 CVNKYSTPEALEHHLQTATHNFPCPHCQ-KVFPCERYL 574 Score = 36.6 bits (83), Expect = 0.16 Identities = 18/55 (32%), Positives = 25/55 (45%) Query: 973 KCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 KCP + C K F L+ H SH+ + CALC + S +L +H H Sbjct: 644 KCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAH 698 Score = 35.4 bits (80), Expect = 0.36 Identities = 22/83 (26%), Positives = 31/83 (37%), Gaps = 6/83 (7%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKC--KICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738 C C S LK H H E+ +KC K C + F H H+ + + Sbjct: 440 CQFCPSKFSTYFQLKSHMTQHKNEQVYKCVVKSCAQTFPKLDTFLEHIKSHQEE----LS 495 Query: 739 HSCPICQKKFTNAVVLQQHIRMH 761 + C +C K F + L H H Sbjct: 496 YRCHLCGKDFPSLYDLGVHQYSH 518 >gi|33438586 zinc finger protein 77 [Homo sapiens] Length = 545 Score = 92.4 bits (228), Expect = 2e-18 Identities = 64/196 (32%), Positives = 91/196 (46%), Gaps = 18/196 (9%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F+C S H R+HT E+P+ C C + S + + H+ TH E P Q Sbjct: 270 CKECGKAFSCPSYFREHVRTHTGEKPYECKHCGKSFSCYSSFRDHVRTHT-GEKPCQCKH 328 Query: 1039 PNFALGPSQSTPSLISSAAPTMI---KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095 G + + S + T E GKA L A +++ G + + Sbjct: 329 ----CGKAFTCYSSLREHGRTHSGEKPYECKECGKAFRYPSS--LRAHMRMHTGEKPYVC 382 Query: 1096 PGLAPMLAPPP--RRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICG 1147 P RR K H+ C+ CGK +S +S+L+IH RTHTGEKPF C CG Sbjct: 383 KQCGKAFGCPTYFRRHVKTHSGVKPYQCKECGKAYSFSSSLRIHVRTHTGEKPFECKHCG 442 Query: 1148 RAFTTKGNLKVHMGTH 1163 +AF+ +L+ H+ TH Sbjct: 443 KAFSCHSSLREHVRTH 458 Score = 82.4 bits (202), Expect = 3e-15 Identities = 62/195 (31%), Positives = 91/195 (46%), Gaps = 16/195 (8%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRR--GCSTMGNLKQHLLTHRLKELPSQL 1036 C CGK F S+L H R HT E+P+VC C + GC T ++H+ TH + P Q Sbjct: 354 CKECGKAFRYPSSLRAHMRMHTGEKPYVCKQCGKAFGCPTY--FRRHVKTHSGVK-PYQC 410 Query: 1037 FDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAG--PQTVM 1094 + A S S + + E GKA + L V+ +G P Sbjct: 411 KECGKAYSFSSSLRIHVRTHTGEK-PFECKHCGKAFSCHSS--LREHVRTHSGEKPYECN 467 Query: 1095 GPGLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGR 1148 G A A ++ + H+ C CGK +S +S+L++H RTHTGE+P+ C CG+ Sbjct: 468 QCGKAFSHAQYFQKHVRSHSGVKPYECTECGKAYSCSSSLRVHVRTHTGERPYECKQCGK 527 Query: 1149 AFTTKGNLKVHMGTH 1163 F +L+ H+ TH Sbjct: 528 TFRYLASLQAHVRTH 542 Score = 81.6 bits (200), Expect = 4e-15 Identities = 36/86 (41%), Positives = 52/86 (60%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P QC C + S S+L++H RTHTGE+PF+CK CG+AF+ +L+ H H + P Sbjct: 407 PYQCKECGKAYSFSSSLRIHVRTHTGEKPFECKHCGKAFSCHSSLREHVRTHSGEKP--- 463 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F++A Q+H+R H G Sbjct: 464 -YECNQCGKAFSHAQYFQKHVRSHSG 488 Score = 75.1 bits (183), Expect = 4e-13 Identities = 35/86 (40%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S+ + H RTHTGE+P +CK CG+AFT +L+ H H + P Sbjct: 295 PYECKHCGKSFSCYSSFRDHVRTHTGEKPCQCKHCGKAFTCYSSLREHGRTHSGEKP--- 351 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F L+ H+RMH G Sbjct: 352 -YECKECGKAFRYPSSLRAHMRMHTG 376 Score = 72.8 bits (177), Expect = 2e-12 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P QC C + +C S+L+ H RTH+GE+P++CK CG+AF +L+ H +H + P Sbjct: 323 PCQCKHCGKAFTCYSSLREHGRTHSGEKPYECKECGKAFRYPSSLRAHMRMHTGEKP--- 379 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F ++H++ H G Sbjct: 380 -YVCKQCGKAFGCPTYFRRHVKTHSG 404 Score = 72.4 bits (176), Expect = 3e-12 Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S + H RTHTGE+P++CK CG++F+ + + H H + P + Sbjct: 267 PYECKECGKAFSCPSYFREHVRTHTGEKPYECKHCGKSFSCYSSFRDHVRTHTGEKPCQC 326 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 +H C K FT L++H R H G Sbjct: 327 KH----CGKAFTCYSSLREHGRTHSG 348 Score = 71.2 bits (173), Expect = 6e-12 Identities = 59/235 (25%), Positives = 87/235 (37%), Gaps = 65/235 (27%) Query: 929 QEIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRERGKCPSTVCGVCGKPFAC 988 Q P+KT+ + P S A S+ ++ K S C CGK F C Sbjct: 177 QSPPMKTQTVEKPCNCQDSRTA------------SVTYVKSLSSK-KSYECQKCGKAFIC 223 Query: 989 KSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFDPNFALGPSQS 1048 S+ H SH ++ C +C + L +H+ TH ++ P + Sbjct: 224 PSSFRGHVNSHHGQKTHACKVCGKTFMYYSYLTRHVRTHTGEK-------------PYEC 270 Query: 1049 TPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGLAPMLAPPPRR 1108 + + P+ + V H GE P Sbjct: 271 KECGKAFSCPSYFREHVRTH-----TGEKP------------------------------ 295 Query: 1109 TPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 + C+ CGK+FS S+ + H RTHTGEKP C CG+AFT +L+ H TH Sbjct: 296 ----YECKHCGKSFSCYSSFRDHVRTHTGEKPCQCKHCGKAFTCYSSLREHGRTH 346 Score = 67.8 bits (164), Expect = 7e-11 Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + SC S+L+ H RTH+GE+P++C CG+AF+ + H H P Sbjct: 435 PFECKHCGKAFSCHSSLREHVRTHSGEKPYECNQCGKAFSHAQYFQKHVRSHSGVKP--- 491 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K ++ + L+ H+R H G Sbjct: 492 -YECTECGKAYSCSSSLRVHVRTHTG 516 Score = 66.2 bits (160), Expect = 2e-10 Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + C + + H +TH+G +P++CK CG+A++ +L+ H H + P Sbjct: 379 PYVCKQCGKAFGCPTYFRRHVKTHSGVKPYQCKECGKAYSFSSSLRIHVRTHTGEKPFEC 438 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 +H C K F+ L++H+R H G Sbjct: 439 KH----CGKAFSCHSSLREHVRTHSG 460 Score = 65.9 bits (159), Expect = 2e-10 Identities = 29/83 (34%), Positives = 42/83 (50%), Gaps = 4/83 (4%) Query: 681 CVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHS 740 C +C + S L H RTHTGE+P++CK CG+AF+ + H H + P + Sbjct: 242 CKVCGKTFMYYSYLTRHVRTHTGEKPYECKECGKAFSCPSYFREHVRTHTGEKP----YE 297 Query: 741 CPICQKKFTNAVVLQQHIRMHMG 763 C C K F+ + H+R H G Sbjct: 298 CKHCGKSFSCYSSFRDHVRTHTG 320 Score = 63.5 bits (153), Expect = 1e-09 Identities = 46/159 (28%), Positives = 67/159 (42%), Gaps = 24/159 (15%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK ++ S+L IH R+HT E+PF C C + S +L++H+ TH E P + Sbjct: 410 CKECGKAYSFSSSLRIHVRTHTGEKPFECKHCGKAFSCHSSLREHVRTHS-GEKPYECNQ 468 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 A +Q + S + E GKA + L V+ G Sbjct: 469 CGKAFSHAQYFQKHVRSHSGVK-PYECTECGKAYSCSSS--LRVHVRTHTGE-------- 517 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTG 1137 + + C+ CGKTF ++LQ H RTH G Sbjct: 518 ------------RPYECKQCGKTFRYLASLQAHVRTHAG 544 Score = 63.2 bits (152), Expect = 2e-09 Identities = 57/185 (30%), Positives = 72/185 (38%), Gaps = 38/185 (20%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F E RSHT +RP C C + CS + + T + E P D Sbjct: 144 CTKCGKAF------ENRQRSHTGQRP--CKECGQACSCLSCQSPPMKTQTV-EKPCNCQD 194 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 A S + +SS E GKA P + G Sbjct: 195 SRTA---SVTYVKSLSSKK----SYECQKCGKAFIC---------------PSSFRGHVN 232 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 + K H C+ CGKTF S L H RTHTGEKP+ C CG+AF+ + Sbjct: 233 S-------HHGQKTHACKVCGKTFMYYSYLTRHVRTHTGEKPYECKECGKAFSCPSYFRE 285 Query: 1159 HMGTH 1163 H+ TH Sbjct: 286 HVRTH 290 Score = 62.8 bits (151), Expect = 2e-09 Identities = 24/52 (46%), Positives = 34/52 (65%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729 P +C C + SC S+L++H RTHTGERP++CK CG+ F +L+ H H Sbjct: 491 PYECTECGKAYSCSSSLRVHVRTHTGERPYECKQCGKTFRYLASLQAHVRTH 542 Score = 62.4 bits (150), Expect = 3e-09 Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 11/98 (11%) Query: 390 LSALMKHRKGKPPNVSVFEPKASAEDPFFK-----------HKCRFCAKVFGSDSALQIH 438 L A M+ G+ P V KA +F+ ++C+ C K + S+L+IH Sbjct: 367 LRAHMRMHTGEKPYVCKQCGKAFGCPTYFRRHVKTHSGVKPYQCKECGKAYSFSSSLRIH 426 Query: 439 LRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +R+HTGE+PF+C CG FS +L+ H + H + P+ Sbjct: 427 VRTHTGEKPFECKHCGKAFSCHSSLREHVRTHSGEKPY 464 Score = 62.0 bits (149), Expect = 4e-09 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S+L+ H R HTGE+P+ CK CG+AF + H H P Sbjct: 351 PYECKECGKAFRYPSSLRAHMRMHTGEKPYVCKQCGKAFGCPTYFRRHVKTHSGVKP--- 407 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K ++ + L+ H+R H G Sbjct: 408 -YQCKECGKAYSFSSSLRIHVRTHTG 432 Score = 62.0 bits (149), Expect = 4e-09 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S + H R+H+G +P++C CG+A++ +L+ H H + P Sbjct: 463 PYECNQCGKAFSHAQYFQKHVRSHSGVKPYECTECGKAYSCSSSLRVHVRTHTGERP--- 519 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F LQ H+R H G Sbjct: 520 -YECKQCGKTFRYLASLQAHVRTHAG 544 Score = 56.2 bits (134), Expect = 2e-07 Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 4/84 (4%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 +C C + C S+ + H +H G++ CK+CG+ F L H H + P + Sbjct: 213 ECQKCGKAFICPSSFRGHVNSHHGQKTHACKVCGKTFMYYSYLTRHVRTHTGEKP----Y 268 Query: 740 SCPICQKKFTNAVVLQQHIRMHMG 763 C C K F+ ++H+R H G Sbjct: 269 ECKECGKAFSCPSYFREHVRTHTG 292 Score = 56.2 bits (134), Expect = 2e-07 Identities = 24/65 (36%), Positives = 38/65 (58%), Gaps = 3/65 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + E PF +C+ C K F S+L+ H+R+H+GE+P++CN CG FS + H + H Sbjct: 431 TGEKPF---ECKHCGKAFSCHSSLREHVRTHSGEKPYECNQCGKAFSHAQYFQKHVRSHS 487 Query: 472 EKYPH 476 P+ Sbjct: 488 GVKPY 492 Score = 56.2 bits (134), Expect = 2e-07 Identities = 20/51 (39%), Positives = 33/51 (64%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRH 470 ++C C K + S+L++H+R+HTGERP++C CG F +L+ H + H Sbjct: 492 YECTECGKAYSCSSSLRVHVRTHTGERPYECKQCGKTFRYLASLQAHVRTH 542 Score = 54.3 bits (129), Expect = 7e-07 Identities = 22/57 (38%), Positives = 32/57 (56%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 H C+ C K F S L H+R+HTGE+P++C CG FS + H + H + P+ Sbjct: 240 HACKVCGKTFMYYSYLTRHVRTHTGEKPYECKECGKAFSCPSYFREHVRTHTGEKPY 296 Score = 54.3 bits (129), Expect = 7e-07 Identities = 28/84 (33%), Positives = 46/84 (54%), Gaps = 5/84 (5%) Query: 421 KCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQM- 479 +C+ C K F S+L+ H R+H+GE+P++C CG F +L+ H + H + P++ Sbjct: 325 QCKHCGKAFTCYSSLREHGRTHSGEKPYECKECGKAFRYPSSLRAHMRMHTGEKPYVCKQ 384 Query: 480 --NPYPVPEYL-DNVPTCSGI-PY 499 + P Y +V T SG+ PY Sbjct: 385 CGKAFGCPTYFRRHVKTHSGVKPY 408 Score = 54.3 bits (129), Expect = 7e-07 Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 3/65 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 S E P+ +C C K F Q H+RSH+G +P++C CG +S +L+VH + H Sbjct: 459 SGEKPY---ECNQCGKAFSHAQYFQKHVRSHSGVKPYECTECGKAYSCSSSLRVHVRTHT 515 Query: 472 EKYPH 476 + P+ Sbjct: 516 GERPY 520 Score = 53.1 bits (126), Expect = 2e-06 Identities = 20/56 (35%), Positives = 33/56 (58%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475 ++C+ C K F S + H+R+HTGE+P++C CG FS + + H + H + P Sbjct: 268 YECKECGKAFSCPSYFREHVRTHTGEKPYECKHCGKSFSCYSSFRDHVRTHTGEKP 323 Score = 52.8 bits (125), Expect = 2e-06 Identities = 20/57 (35%), Positives = 35/57 (61%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F S+ + H+R+HTGE+P +C CG F+ +L+ H + H + P+ Sbjct: 296 YECKHCGKSFSCYSSFRDHVRTHTGEKPCQCKHCGKAFTCYSSLREHGRTHSGEKPY 352 Score = 52.0 bits (123), Expect = 4e-06 Identities = 32/127 (25%), Positives = 49/127 (38%), Gaps = 26/127 (20%) Query: 659 SETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERP------------ 706 SE +K + EN + T C C + SC S +T T E+P Sbjct: 142 SECTKCGKAFENRQRSHTGQRPCKECGQACSCLSCQSPPMKTQTVEKPCNCQDSRTASVT 201 Query: 707 ----------FKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQ 756 ++C+ CG+AF + + H H + H+C +C K F L + Sbjct: 202 YVKSLSSKKSYECQKCGKAFICPSSFRGHVNSHHGQK----THACKVCGKTFMYYSYLTR 257 Query: 757 HIRMHMG 763 H+R H G Sbjct: 258 HVRTHTG 264 Score = 51.6 bits (122), Expect = 5e-06 Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 S E P+ +C+ C K F S+L+ H+R HTGE+P+ C CG F + H + H Sbjct: 347 SGEKPY---ECKECGKAFRYPSSLRAHMRMHTGEKPYVCKQCGKAFGCPTYFRRHVKTHS 403 Query: 472 EKYPH 476 P+ Sbjct: 404 GVKPY 408 Score = 42.0 bits (97), Expect = 0.004 Identities = 17/57 (29%), Positives = 29/57 (50%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F S+ + H+ SH G++ C +CG F L H + H + P+ Sbjct: 212 YECQKCGKAFICPSSFRGHVNSHHGQKTHACKVCGKTFMYYSYLTRHVRTHTGEKPY 268 Score = 36.2 bits (82), Expect = 0.21 Identities = 15/36 (41%), Positives = 21/36 (58%) Query: 1118 CGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTK 1153 CG+T S + L +H+ T KP CT CG+AF + Sbjct: 119 CGETLSQTANLLVHKSYPTEAKPSECTKCGKAFENR 154 >gi|21699060 zinc finger protein 564 [Homo sapiens] Length = 553 Score = 91.7 bits (226), Expect = 4e-18 Identities = 62/197 (31%), Positives = 88/197 (44%), Gaps = 20/197 (10%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C VCG+ F S + H R+HT E+P+ C C + S+ N++ H TH E P + + Sbjct: 311 CKVCGRAFIFPSYVRKHERTHTGEKPYECNKCGKTFSSSSNVRTHERTHT-GEKPYECKE 369 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP-- 1096 A + S MIK +G K G P+ Q+ T P Sbjct: 370 CGKAF-------ISLPSVRRHMIKHTGDGPYKCQVCGRAFDCPSSFQIHERTHTGEKPYE 422 Query: 1097 ----GLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTIC 1146 G A + R+ H CQ CGK F S+++ HERTHTGEKP+ C C Sbjct: 423 CQVCGKAFISLKRIRKHMILHTGDGPYKCQVCGKAFDCPSSVRTHERTHTGEKPYECKEC 482 Query: 1147 GRAFTTKGNLKVHMGTH 1163 G+AF ++++H TH Sbjct: 483 GKAFNYASSIRIHERTH 499 Score = 89.4 bits (220), Expect = 2e-17 Identities = 49/185 (26%), Positives = 79/185 (42%), Gaps = 52/185 (28%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C VCG+ F C S+ +IH R+HT E+P+ C +C + ++ +++H++ H Sbjct: 395 CQVCGRAFDCPSSFQIHERTHTGEKPYECQVCGKAFISLKRIRKHMILHT---------- 444 Query: 1039 PNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGPGL 1098 +G K G+ P+ V+ T Sbjct: 445 --------------------------GDGPYKCQVCGKAFDCPSSVRTHERTHT------ 472 Query: 1099 APMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKV 1158 K + C+ CGK F+ AS+++IHERTHTGEKP+ C CG+ F+ + + Sbjct: 473 ----------GEKPYECKECGKAFNYASSIRIHERTHTGEKPYECKQCGKTFSYSSSFQR 522 Query: 1159 HMGTH 1163 H H Sbjct: 523 HERAH 527 Score = 89.0 bits (219), Expect = 3e-17 Identities = 60/194 (30%), Positives = 82/194 (42%), Gaps = 14/194 (7%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F S IH R+HT E+P C C + + N + H++ H + P + Sbjct: 255 CQECGKAFDRPSLFRIHERTHTGEKPHECKQCGKAFISFTNFQSHMIRHT-GDGPYKCK- 312 Query: 1039 PNFALGPSQSTPSLISSAAPTMI---KMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMG 1095 G + PS + T E N GK + P Sbjct: 313 ---VCGRAFIFPSYVRKHERTHTGEKPYECNKCGKTFSSSSNVRTHERTHTGEKPYECKE 369 Query: 1096 PGLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRA 1149 G A + P RR +H CQ CG+ F S+ QIHERTHTGEKP+ C +CG+A Sbjct: 370 CGKAFISLPSVRRHMIKHTGDGPYKCQVCGRAFDCPSSFQIHERTHTGEKPYECQVCGKA 429 Query: 1150 FTTKGNLKVHMGTH 1163 F + ++ HM H Sbjct: 430 FISLKRIRKHMILH 443 Score = 81.3 bits (199), Expect = 6e-15 Identities = 64/207 (30%), Positives = 86/207 (41%), Gaps = 30/207 (14%) Query: 979 CGVCGKPFACKSALEIHYRSHTK----------ERPFVCALCRRGCSTMGNLKQHLLTHR 1028 C +CGK F S+L H RSH E+P+ C C + S+ + ++H TH Sbjct: 105 CSLCGKVFMHHSSLSRHIRSHLGHKPYDYQEYGEKPYKCKQCGKAFSSCQSFRRHERTHT 164 Query: 1029 LKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPA 1088 E P +A + S MIK +G K G+ P+ Q+ Sbjct: 165 -GEKP-------YACPECGKAFISLPSVRRHMIKHTGDGPYKCQECGKAFDRPSLFQIHE 216 Query: 1089 GPQTVMGP------GLAPMLAPPPRRTPKQHN------CQSCGKTFSSASALQIHERTHT 1136 T P A + P +R +H CQ CGK F S +IHERTHT Sbjct: 217 RTHTGEKPYECQECAKAFISLPSFQRHMIRHTGDGPYKCQECGKAFDRPSLFRIHERTHT 276 Query: 1137 GEKPFGCTICGRAFTTKGNLKVHMGTH 1163 GEKP C CG+AF + N + HM H Sbjct: 277 GEKPHECKQCGKAFISFTNFQSHMIRH 303 Score = 74.3 bits (181), Expect = 7e-13 Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C +C + C S+++ H RTHTGE+P++CK CG+AF +++ H H + P Sbjct: 448 PYKCQVCGKAFDCPSSVRTHERTHTGEKPYECKECGKAFNYASSIRIHERTHTGEKP--- 504 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + Q+H R H G Sbjct: 505 -YECKQCGKTFSYSSSFQRHERAHNG 529 Score = 73.9 bits (180), Expect = 9e-13 Identities = 30/86 (34%), Positives = 49/86 (56%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C +C R C S+ ++H RTHTGE+P++C++CG+AF + ++ H +H P Sbjct: 392 PYKCQVCGRAFDCPSSFQIHERTHTGEKPYECQVCGKAFISLKRIRKHMILHTGDGP--- 448 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C +C K F ++ H R H G Sbjct: 449 -YKCQVCGKAFDCPSSVRTHERTHTG 473 Score = 68.9 bits (167), Expect = 3e-11 Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C +C R S ++ H RTHTGE+P++C CG+ F++ N++TH H + P Sbjct: 308 PYKCKVCGRAFIFPSYVRKHERTHTGEKPYECNKCGKTFSSSSNVRTHERTHTGEKP--- 364 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F + +++H+ H G Sbjct: 365 -YECKECGKAFISLPSVRRHMIKHTG 389 Score = 64.7 bits (156), Expect = 6e-10 Identities = 30/86 (34%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S S ++ H RTHTGE+P++CK CG+AF + +++ H H P Sbjct: 336 PYECNKCGKTFSSSSNVRTHERTHTGEKPYECKECGKAFISLPSVRRHMIKHTGDGP--- 392 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C +C + F Q H R H G Sbjct: 393 -YKCQVCGRAFDCPSSFQIHERTHTG 417 Score = 63.2 bits (152), Expect = 2e-09 Identities = 38/128 (29%), Positives = 65/128 (50%), Gaps = 19/128 (14%) Query: 651 GLLDSMQTSETSKL--QQLVENIDKKMTD---PNQCVICHRVLSCQSALKMHYRTHTG-- 703 GL +S + + + Q L N++KK+ P +C +C +V S+L H R+H G Sbjct: 70 GLSESKEYDQCGEAFSQILNLNLNKKIPTIVRPCECSLCGKVFMHHSSLSRHIRSHLGHK 129 Query: 704 --------ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQ 755 E+P+KCK CG+AF++ + + H H + P ++CP C K F + ++ Sbjct: 130 PYDYQEYGEKPYKCKQCGKAFSSCQSFRRHERTHTGEKP----YACPECGKAFISLPSVR 185 Query: 756 QHIRMHMG 763 +H+ H G Sbjct: 186 RHMIKHTG 193 Score = 63.2 bits (152), Expect = 2e-09 Identities = 29/86 (33%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S ++H RTHTGE+P +CK CG+AF + N ++H H P Sbjct: 252 PYKCQECGKAFDRPSLFRIHERTHTGEKPHECKQCGKAFISFTNFQSHMIRHTGDGP--- 308 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C +C + F +++H R H G Sbjct: 309 -YKCKVCGRAFIFPSYVRKHERTHTG 333 Score = 60.8 bits (146), Expect = 8e-09 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S + + H RTHTGE+P+ C CG+AF + +++ H H P Sbjct: 140 PYKCKQCGKAFSSCQSFRRHERTHTGEKPYACPECGKAFISLPSVRRHMIKHTGDGP--- 196 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F + Q H R H G Sbjct: 197 -YKCQECGKAFDRPSLFQIHERTHTG 221 Score = 60.8 bits (146), Expect = 8e-09 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + +++ H HTG+ P+KC++CGRAF + + H H + P Sbjct: 364 PYECKECGKAFISLPSVRRHMIKHTGDGPYKCQVCGRAFDCPSSFQIHERTHTGEKP--- 420 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C +C K F + +++H+ +H G Sbjct: 421 -YECQVCGKAFISLKRIRKHMILHTG 445 Score = 59.7 bits (143), Expect = 2e-08 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 3/78 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P +V E + E P+ +C+ C K F S+++IH R+HTGE+P++C CG FS Sbjct: 461 PSSVRTHERTHTGEKPY---ECKECGKAFNYASSIRIHERTHTGEKPYECKQCGKTFSYS 517 Query: 461 GNLKVHFQRHKEKYPHIQ 478 + + H + H P+++ Sbjct: 518 SSFQRHERAHNGDKPYVK 535 Score = 59.3 bits (142), Expect = 2e-08 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P++C C + + + H HTG+ P+KCK+CGRAF ++ H H + P Sbjct: 280 PHECKQCGKAFISFTNFQSHMIRHTGDGPYKCKVCGRAFIFPSYVRKHERTHTGEKP--- 336 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+++ ++ H R H G Sbjct: 337 -YECNKCGKTFSSSSNVRTHERTHTG 361 Score = 58.5 bits (140), Expect = 4e-08 Identities = 22/57 (38%), Positives = 37/57 (64%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C + F S ++ H R+HTGE+P++CN CG FS+ N++ H + H + P+ Sbjct: 309 YKCKVCGRAFIFPSYVRKHERTHTGEKPYECNKCGKTFSSSSNVRTHERTHTGEKPY 365 Score = 57.4 bits (137), Expect = 9e-08 Identities = 20/57 (35%), Positives = 37/57 (64%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S+++ H R+HTGE+P++C CG F+ ++++H + H + P+ Sbjct: 449 YKCQVCGKAFDCPSSVRTHERTHTGEKPYECKECGKAFNYASSIRIHERTHTGEKPY 505 Score = 57.0 bits (136), Expect = 1e-07 Identities = 27/86 (31%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S ++H RTHTGE+P++C+ C +AF + + + H H P Sbjct: 196 PYKCQECGKAFDRPSLFQIHERTHTGEKPYECQECAKAFISLPSFQRHMIRHTGDGP--- 252 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F + + H R H G Sbjct: 253 -YKCQECGKAFDRPSLFRIHERTHTG 277 Score = 56.6 bits (135), Expect = 2e-07 Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKG 461 P+V K + + P+ KC+ C + F S+ QIH R+HTGE+P++C +CG F + Sbjct: 378 PSVRRHMIKHTGDGPY---KCQVCGRAFDCPSSFQIHERTHTGEKPYECQVCGKAFISLK 434 Query: 462 NLKVHFQRHKEKYPH 476 ++ H H P+ Sbjct: 435 RIRKHMILHTGDGPY 449 Score = 55.1 bits (131), Expect = 4e-07 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + + H HTG+ P+KC+ CG+AF + H H + P Sbjct: 224 PYECQECAKAFISLPSFQRHMIRHTGDGPYKCQECGKAFDRPSLFRIHERTHTGEKP--- 280 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 H C C K F + Q H+ H G Sbjct: 281 -HECKQCGKAFISFTNFQSHMIRHTG 305 Score = 55.1 bits (131), Expect = 4e-07 Identities = 20/57 (35%), Positives = 34/57 (59%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPP 734 P +C C + + S++++H RTHTGE+P++CK CG+ F+ + + H H P Sbjct: 476 PYECKECGKAFNYASSIRIHERTHTGEKPYECKQCGKTFSYSSSFQRHERAHNGDKP 532 Score = 53.9 bits (128), Expect = 1e-06 Identities = 23/57 (40%), Positives = 32/57 (56%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S +IH R+HTGE+P +C CG F + N + H RH P+ Sbjct: 253 YKCQECGKAFDRPSLFRIHERTHTGEKPHECKQCGKAFISFTNFQSHMIRHTGDGPY 309 Score = 53.5 bits (127), Expect = 1e-06 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Query: 400 KPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFST 459 +P + E + E P+ +C+ CAK F S + Q H+ HTG+ P+KC CG F Sbjct: 208 RPSLFQIHERTHTGEKPY---ECQECAKAFISLPSFQRHMIRHTGDGPYKCQECGKAFDR 264 Query: 460 KGNLKVHFQRHKEKYPH 476 ++H + H + PH Sbjct: 265 PSLFRIHERTHTGEKPH 281 Score = 53.5 bits (127), Expect = 1e-06 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGN 462 NV E + E P+ +C+ C K F S +++ H+ HTG+ P+KC +CG F + Sbjct: 351 NVRTHERTHTGEKPY---ECKECGKAFISLPSVRRHMIKHTGDGPYKCQVCGRAFDCPSS 407 Query: 463 LKVHFQRHKEKYPH 476 ++H + H + P+ Sbjct: 408 FQIHERTHTGEKPY 421 Score = 53.1 bits (126), Expect = 2e-06 Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 3/75 (4%) Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKG 461 P+V K + + P+ KC+ C K F S QIH R+HTGE+P++C C F + Sbjct: 182 PSVRRHMIKHTGDGPY---KCQECGKAFDRPSLFQIHERTHTGEKPYECQECAKAFISLP 238 Query: 462 NLKVHFQRHKEKYPH 476 + + H RH P+ Sbjct: 239 SFQRHMIRHTGDGPY 253 Score = 53.1 bits (126), Expect = 2e-06 Identities = 25/76 (32%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P V E + E P+ +C C K F S S ++ H R+HTGE+P++C CG F + Sbjct: 321 PSYVRKHERTHTGEKPY---ECNKCGKTFSSSSNVRTHERTHTGEKPYECKECGKAFISL 377 Query: 461 GNLKVHFQRHKEKYPH 476 +++ H +H P+ Sbjct: 378 PSVRRHMIKHTGDGPY 393 Score = 52.8 bits (125), Expect = 2e-06 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + +++ H HTG+ P+KC+ CG+AF + H H + P Sbjct: 168 PYACPECGKAFISLPSVRRHMIKHTGDGPYKCQECGKAFDRPSLFQIHERTHTGEKP--- 224 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F + Q+H+ H G Sbjct: 225 -YECQECAKAFISLPSFQRHMIRHTG 249 Score = 52.8 bits (125), Expect = 2e-06 Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 3/76 (3%) Query: 401 PPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 P + + E + E P+ +C+ C K F S ++ H+ HTG+ P+KC +CG F Sbjct: 405 PSSFQIHERTHTGEKPY---ECQVCGKAFISLKRIRKHMILHTGDGPYKCQVCGKAFDCP 461 Query: 461 GNLKVHFQRHKEKYPH 476 +++ H + H + P+ Sbjct: 462 SSVRTHERTHTGEKPY 477 Score = 52.0 bits (123), Expect = 4e-06 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Query: 400 KPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFST 459 +P + E + E P H+C+ C K F S + Q H+ HTG+ P+KC +CG F Sbjct: 264 RPSLFRIHERTHTGEKP---HECKQCGKAFISFTNFQSHMIRHTGDGPYKCKVCGRAFIF 320 Query: 460 KGNLKVHFQRHKEKYPH 476 ++ H + H + P+ Sbjct: 321 PSYVRKHERTHTGEKPY 337 Score = 50.1 bits (118), Expect = 1e-05 Identities = 20/57 (35%), Positives = 33/57 (57%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F S + + H R+HTGE+P+ C CG F + +++ H +H P+ Sbjct: 141 YKCKQCGKAFSSCQSFRRHERTHTGEKPYACPECGKAFISLPSVRRHMIKHTGDGPY 197 Score = 48.1 bits (113), Expect = 5e-05 Identities = 28/76 (36%), Positives = 37/76 (48%), Gaps = 16/76 (21%) Query: 421 KCRFCAKVFGSDSALQIHLRSHT----------GERPFKCNICGNRFSTKGNLKVHFQRH 470 +C C KVF S+L H+RSH GE+P+KC CG FS+ + F+RH Sbjct: 104 ECSLCGKVFMHHSSLSRHIRSHLGHKPYDYQEYGEKPYKCKQCGKAFSSCQS----FRRH 159 Query: 471 KEKYPHIQMNPYPVPE 486 + H PY PE Sbjct: 160 ER--THTGEKPYACPE 173 Score = 44.7 bits (104), Expect = 6e-04 Identities = 18/57 (31%), Positives = 30/57 (52%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 + C C K F S +++ H+ HTG+ P+KC CG F ++H + H + P+ Sbjct: 169 YACPECGKAFISLPSVRRHMIKHTGDGPYKCQECGKAFDRPSLFQIHERTHTGEKPY 225 Score = 41.6 bits (96), Expect = 0.005 Identities = 24/103 (23%), Positives = 44/103 (42%), Gaps = 6/103 (5%) Query: 667 LVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHF 726 L ++++ +++ + C S L ++ + T RP +C +CG+ F +L H Sbjct: 63 LRNHMEEGLSESKEYDQCGEAFSQILNLNLNKKIPTIVRPCECSLCGKVFMHHSSLSRHI 122 Query: 727 GVHRAKPPLRVQ------HSCPICQKKFTNAVVLQQHIRMHMG 763 H P Q + C C K F++ ++H R H G Sbjct: 123 RSHLGHKPYDYQEYGEKPYKCKQCGKAFSSCQSFRRHERTHTG 165 Score = 37.0 bits (84), Expect = 0.12 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 3/58 (5%) Query: 403 NVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTK 460 ++ + E + E P+ +C+ C K F S+ Q H R+H G++P+ N+ F T+ Sbjct: 491 SIRIHERTHTGEKPY---ECKQCGKTFSYSSSFQRHERAHNGDKPYVKNVGKLSFITQ 545 Score = 36.6 bits (83), Expect = 0.16 Identities = 14/47 (29%), Positives = 27/47 (57%) Query: 1118 CGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHM 1164 CG+ FS L ++++ T +P C++CG+ F +L H+ +H+ Sbjct: 80 CGEAFSQILNLNLNKKIPTIVRPCECSLCGKVFMHHSSLSRHIRSHL 126 Score = 32.0 bits (71), Expect = 4.0 Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 6/70 (8%) Query: 425 CAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPV 484 C + F L ++ + T RP +C++CG F +L H + H+ PY Sbjct: 80 CGEAFSQILNLNLNKKIPTIVRPCECSLCGKVFMHHSSLSRHIR------SHLGHKPYDY 133 Query: 485 PEYLDNVPTC 494 EY + C Sbjct: 134 QEYGEKPYKC 143 Score = 31.2 bits (69), Expect = 6.8 Identities = 12/42 (28%), Positives = 22/42 (52%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTK 719 P +C C + S S+ + H R H G++P+ + +F T+ Sbjct: 504 PYECKQCGKTFSYSSSFQRHERAHNGDKPYVKNVGKLSFITQ 545 Score = 31.2 bits (69), Expect = 6.8 Identities = 11/28 (39%), Positives = 18/28 (64%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFV 1006 C CGK F+ S+ + H R+H ++P+V Sbjct: 507 CKQCGKTFSYSSSFQRHERAHNGDKPYV 534 >gi|153791350 replication initiator 1 isoform 1 [Homo sapiens] Length = 567 Score = 91.7 bits (226), Expect = 4e-18 Identities = 73/221 (33%), Positives = 93/221 (42%), Gaps = 27/221 (12%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037 C CGK F K L H R HT ERP C C + + L H H K P + Sbjct: 238 CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 297 Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMAL-GEGPP-LPAGVQVPAGPQTVMG 1095 F + P+L+S + K+ G A A G G P LPAG Q A T Sbjct: 298 GRRF-----RHKPNLLSHS-----KIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAV 347 Query: 1096 PGLAPMLAPPPRRTPKQ-----------HNCQSCGKTFSSASALQIHERTHTGEKPFGCT 1144 P L P PPP P+ ++C CG++F L+ H+R HTGE+PF C Sbjct: 348 P-LKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCA 406 Query: 1145 ICGRAFTTKGNLKVHMGTHMWNN--APARRGRRLSVENPMA 1183 CG+ F K +L H H A GRR S + +A Sbjct: 407 ECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA 447 Score = 85.5 bits (210), Expect = 3e-16 Identities = 101/386 (26%), Positives = 134/386 (34%), Gaps = 59/386 (15%) Query: 382 ATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRS 441 A A AL P R P V+ P A D F+ C C K F L H R Sbjct: 207 AAAKALGP-------RPRGRPAVTAPRPGGDAVDRPFQ--CACCGKRFRHKPNLIAHRRV 257 Query: 442 HTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGM 501 HTGERP +C CG RF+ K L H + H + P+ Sbjct: 258 HTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPY------------------------- 292 Query: 502 SLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASS 561 P K KP L L + G S A P SPQ P+ Sbjct: 293 ---PCKECGRRFRHKPNL--------LSHSKIHKRSEG---SAQAAPGPGSPQLPAGPQE 338 Query: 562 ECASLSPGLN---HVESGVSATAESPQSLLGGPP-LTKAEPVSLPCTNARAGDAPVGAQA 617 A +P + E A E PQ + PP L + R A Sbjct: 339 SAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHT 398 Query: 618 SAAPTSVDGAPTSLGSPG-LPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMT 676 P + + G L A S + PF + S+ S L D Sbjct: 399 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA--AHRRDHAPD 456 Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736 P C C + + L H R HTGE+P+ C CG+AF+ K NL +H +H + P Sbjct: 457 RPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERP-- 514 Query: 737 VQHSCPICQKKFTNAVVLQQHIRMHM 762 ++CP C + F+ L H + H+ Sbjct: 515 --YACPDCDRSFSQKSNLITHRKSHI 538 Score = 84.0 bits (206), Expect = 9e-16 Identities = 79/274 (28%), Positives = 96/274 (35%), Gaps = 54/274 (19%) Query: 901 SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960 S + AP G P A E +PLK PA P G P EA Sbjct: 317 SEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLK------PAQEPPPGAPPEHPQDPIEA 370 Query: 961 PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020 P SL C CG+ F + L H R HT ERPF CA C + Sbjct: 371 PPSLYS------------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGK---- 414 Query: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080 K HL+ H S + S E G+ + G Sbjct: 415 KTHLVAH-----------------------SRVHSGERPFACEEC---GRRFSQGSHLAA 448 Query: 1081 PAGVQVPAGPQTVMGPGLA----PMLAPPPR--RTPKQHNCQSCGKTFSSASALQIHERT 1134 P P G A P LA R K + C CGK FS S L H R Sbjct: 449 HRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRI 508 Query: 1135 HTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168 HTGE+P+ C C R+F+ K NL H +H+ + A Sbjct: 509 HTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 542 Score = 71.6 bits (174), Expect = 5e-12 Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 20/229 (8%) Query: 960 APFSLLFLSRERGKCPST--VCGVCGKPFACKSALEIHYRSHT-KERPFVCALCRRGCST 1016 APF L P C +CG+ F AL +H R+H+ +RP C C R Sbjct: 97 APFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWR 156 Query: 1017 MGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKM-EVNGHGKAMALG 1075 L+ HL R P+ P +S A + + E A ALG Sbjct: 157 RKQLRAHL---RRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALG 213 Query: 1076 EGPPLPAGVQVP-AGPQTVMGPGLAPMLAPPPRRTP------------KQHNCQSCGKTF 1122 P V P G V P R P + H C CGK F Sbjct: 214 PRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRF 273 Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPAR 1171 ++ L H R HTGEKP+ C CGR F K NL H H + A+ Sbjct: 274 TNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 322 Score = 67.8 bits (164), Expect = 7e-11 Identities = 88/335 (26%), Positives = 114/335 (34%), Gaps = 72/335 (21%) Query: 445 ERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLP 504 +RPF+C CG RF K NL H + H + PH P C Sbjct: 233 DRPFQCACCGKRFRHKPNLIAHRRVHTGERPH-------------QCPECG--------- 270 Query: 505 PEKPVTTWLDSKPVLPTVPT-SVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSEC 563 K T +KP L + G + P + P+ S+ +R S Sbjct: 271 --KRFT----NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKR----SEGS 320 Query: 564 ASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTS 623 A +PG SPQ L GP + AEP P + P P Sbjct: 321 AQAAPGPG-----------SPQ-LPAGPQESAAEPT--PAVPLKPAQEPPPGAPPEHPQD 366 Query: 624 VDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSK----LQQLVENIDKKM---- 675 AP SL S + F L + Q T + + +N KK Sbjct: 367 PIEAPPSLYS------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVA 420 Query: 676 -------TDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGV 728 P C C R S S L H R H +RPF C CG+AF K L H + Sbjct: 421 HSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRI 480 Query: 729 HRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 H + P + CP C K F+ L H R+H G Sbjct: 481 HTGEKP----YVCPDCGKAFSQKSNLVSHRRIHTG 511 Score = 64.7 bits (156), Expect = 6e-10 Identities = 41/122 (33%), Positives = 50/122 (40%), Gaps = 14/122 (11%) Query: 354 AAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASA 413 AAPG SP LP P P V PL + G PP P+ Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAV----------PLKPAQEPPPGAPPE----HPQDPI 368 Query: 414 EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473 E P + C C + F + L+ H R HTGERPF C CG F K +L H + H + Sbjct: 369 EAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGE 428 Query: 474 YP 475 P Sbjct: 429 RP 430 Score = 63.2 bits (152), Expect = 2e-09 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 24/162 (14%) Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375 AAP P +P PQ +A+ + PA P PG P P+ + P Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEP------PPGAP----PEHPQDPIEAPP 372 Query: 376 PLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSAL 435 L S + L H++ + + E PF C C K FG + L Sbjct: 373 SLYSCDDCGRSFRLERFLRAHQR-----------QHTGERPF---TCAECGKNFGKKTHL 418 Query: 436 QIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 H R H+GERPF C CG RFS +L H + H P + Sbjct: 419 VAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFV 460 Score = 46.2 bits (108), Expect = 2e-04 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 1/89 (1%) Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738 ++C C R AL +H R P C CGR F L H VH A P + Sbjct: 57 HRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATP-DLG 115 Query: 739 HSCPICQKKFTNAVVLQQHIRMHMGGQIP 767 +C +C + F V L H+R H + P Sbjct: 116 FACHLCGQSFRGWVALVLHLRAHSAAKRP 144 Score = 42.0 bits (97), Expect = 0.004 Identities = 63/250 (25%), Positives = 77/250 (30%), Gaps = 73/250 (29%) Query: 294 RPESGASTPGGPAEPSAPAAP---SAAPAPAAP---APAPAPQSAASSQPQSASTPPALA 347 R E A GP P PA P +A P PA P A P P + PP+L Sbjct: 316 RSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLY 375 Query: 348 PGSLLGAAPGLPSPLL----------PQTSAS-GVIFPNP--LVSIAATANALDPL---- 390 G + L L P T A G F LV+ + + P Sbjct: 376 SCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEE 435 Query: 391 --------SALMKHRKGKPPNVSVFEP---KASAEDPFFK-----------HKCRFCAKV 428 S L HR+ P+ P KA P+ + C C K Sbjct: 436 CGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKA 495 Query: 429 FGSDSALQIHLRSHTGERP----------------------------FKCNICGNRFSTK 460 F S L H R HTGERP F C ICG F + Sbjct: 496 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 555 Query: 461 GNLKVHFQRH 470 L H ++H Sbjct: 556 ERLLAHQKKH 565 Score = 41.6 bits (96), Expect = 0.005 Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 24/157 (15%) Query: 892 GSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAP 951 GSP L A P P+ + P PE PQ+ E P S + G + Sbjct: 328 GSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQD---PIEAPPSLYSCDDCGRSF 384 Query: 952 G-----RAGIKE---EAPFSLLFLSRERGKCPSTV-------------CGVCGKPFACKS 990 RA ++ E PF+ + GK V C CG+ F+ S Sbjct: 385 RLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGS 444 Query: 991 ALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 L H R H +RPFVC C + L H H Sbjct: 445 HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 481 Score = 40.0 bits (92), Expect = 0.015 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHT-GERPFKCNICGNRFSTK 460 P +++ +A P C C + F AL +HLR+H+ +RP C C RF + Sbjct: 98 PFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRR 157 Query: 461 GNLKVHFQR 469 L+ H +R Sbjct: 158 KQLRAHLRR 166 Score = 39.3 bits (90), Expect = 0.025 Identities = 21/68 (30%), Positives = 29/68 (42%) Query: 410 KASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQR 469 ++ A+ P H+C C + F AL +H R P C CG RF L +H Q Sbjct: 47 QSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQV 106 Query: 470 HKEKYPHI 477 H P + Sbjct: 107 HAAATPDL 114 Score = 37.7 bits (86), Expect = 0.072 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%) Query: 681 CVICHRVLSCQSALKMHYRTHTG-ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 C +C + AL +H R H+ +RP C C R F + L+ H + R PP Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAH--LRRCHPPAPEAR 175 Query: 740 S--CPICQKKFTNAVVLQQHIRMHM 762 C C + F L H R+H+ Sbjct: 176 PFICGNCGRSFAQWDQLVAHKRVHV 200 Score = 35.8 bits (81), Expect = 0.27 Identities = 28/101 (27%), Positives = 35/101 (34%), Gaps = 12/101 (11%) Query: 1072 MALGEGPPLPAGVQVPAGPQTV---------MGPGLAPMLAPPPRRTPKQHNCQSCGKTF 1122 +A+G P PQT+ G +A A P R H C C + F Sbjct: 10 LAMGLAQPRLLSGPSQESPQTLGKESRGLRQQGTSVAQSGAQAPGRA---HRCAHCRRHF 66 Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 AL +H R P C CGR F L +H H Sbjct: 67 PGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH 107 Score = 35.8 bits (81), Expect = 0.27 Identities = 18/52 (34%), Positives = 24/52 (46%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729 P C C R S +S L H ++H + F C ICG+ F + L H H Sbjct: 514 PYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565 Score = 33.5 bits (75), Expect = 1.4 Identities = 16/49 (32%), Positives = 23/49 (46%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 C C + F+ KS L H +SH ++ F CA+C + L H H Sbjct: 517 CPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565 Score = 31.2 bits (69), Expect = 6.8 Identities = 35/125 (28%), Positives = 41/125 (32%), Gaps = 19/125 (15%) Query: 47 GEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPE------DFPEPSPA 100 GE C +C F H+R T + P P E P Sbjct: 260 GERPHQCPECGKRFTNKPYLTSHRRIHTG---------EKPYPCKECGRRFRHKPNLLSH 310 Query: 101 SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPA--PPTPA 158 S +R+E A G + A P E AEP A P A PPP AP P P Sbjct: 311 SKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPL--KPAQEPPPGAPPEHPQDPI 368 Query: 159 YGAPS 163 PS Sbjct: 369 EAPPS 373 >gi|153792539 replication initiator 1 isoform 1 [Homo sapiens] Length = 567 Score = 91.7 bits (226), Expect = 4e-18 Identities = 73/221 (33%), Positives = 93/221 (42%), Gaps = 27/221 (12%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037 C CGK F K L H R HT ERP C C + + L H H K P + Sbjct: 238 CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 297 Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMAL-GEGPP-LPAGVQVPAGPQTVMG 1095 F + P+L+S + K+ G A A G G P LPAG Q A T Sbjct: 298 GRRF-----RHKPNLLSHS-----KIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAV 347 Query: 1096 PGLAPMLAPPPRRTPKQ-----------HNCQSCGKTFSSASALQIHERTHTGEKPFGCT 1144 P L P PPP P+ ++C CG++F L+ H+R HTGE+PF C Sbjct: 348 P-LKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCA 406 Query: 1145 ICGRAFTTKGNLKVHMGTHMWNN--APARRGRRLSVENPMA 1183 CG+ F K +L H H A GRR S + +A Sbjct: 407 ECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA 447 Score = 85.5 bits (210), Expect = 3e-16 Identities = 101/386 (26%), Positives = 134/386 (34%), Gaps = 59/386 (15%) Query: 382 ATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRS 441 A A AL P R P V+ P A D F+ C C K F L H R Sbjct: 207 AAAKALGP-------RPRGRPAVTAPRPGGDAVDRPFQ--CACCGKRFRHKPNLIAHRRV 257 Query: 442 HTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGM 501 HTGERP +C CG RF+ K L H + H + P+ Sbjct: 258 HTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPY------------------------- 292 Query: 502 SLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASS 561 P K KP L L + G S A P SPQ P+ Sbjct: 293 ---PCKECGRRFRHKPNL--------LSHSKIHKRSEG---SAQAAPGPGSPQLPAGPQE 338 Query: 562 ECASLSPGLN---HVESGVSATAESPQSLLGGPP-LTKAEPVSLPCTNARAGDAPVGAQA 617 A +P + E A E PQ + PP L + R A Sbjct: 339 SAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHT 398 Query: 618 SAAPTSVDGAPTSLGSPG-LPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMT 676 P + + G L A S + PF + S+ S L D Sbjct: 399 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA--AHRRDHAPD 456 Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736 P C C + + L H R HTGE+P+ C CG+AF+ K NL +H +H + P Sbjct: 457 RPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERP-- 514 Query: 737 VQHSCPICQKKFTNAVVLQQHIRMHM 762 ++CP C + F+ L H + H+ Sbjct: 515 --YACPDCDRSFSQKSNLITHRKSHI 538 Score = 84.0 bits (206), Expect = 9e-16 Identities = 79/274 (28%), Positives = 96/274 (35%), Gaps = 54/274 (19%) Query: 901 SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960 S + AP G P A E +PLK PA P G P EA Sbjct: 317 SEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLK------PAQEPPPGAPPEHPQDPIEA 370 Query: 961 PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020 P SL C CG+ F + L H R HT ERPF CA C + Sbjct: 371 PPSLYS------------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGK---- 414 Query: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080 K HL+ H S + S E G+ + G Sbjct: 415 KTHLVAH-----------------------SRVHSGERPFACEEC---GRRFSQGSHLAA 448 Query: 1081 PAGVQVPAGPQTVMGPGLA----PMLAPPPR--RTPKQHNCQSCGKTFSSASALQIHERT 1134 P P G A P LA R K + C CGK FS S L H R Sbjct: 449 HRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRI 508 Query: 1135 HTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168 HTGE+P+ C C R+F+ K NL H +H+ + A Sbjct: 509 HTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 542 Score = 71.6 bits (174), Expect = 5e-12 Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 20/229 (8%) Query: 960 APFSLLFLSRERGKCPST--VCGVCGKPFACKSALEIHYRSHT-KERPFVCALCRRGCST 1016 APF L P C +CG+ F AL +H R+H+ +RP C C R Sbjct: 97 APFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWR 156 Query: 1017 MGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKM-EVNGHGKAMALG 1075 L+ HL R P+ P +S A + + E A ALG Sbjct: 157 RKQLRAHL---RRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALG 213 Query: 1076 EGPPLPAGVQVP-AGPQTVMGPGLAPMLAPPPRRTP------------KQHNCQSCGKTF 1122 P V P G V P R P + H C CGK F Sbjct: 214 PRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRF 273 Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPAR 1171 ++ L H R HTGEKP+ C CGR F K NL H H + A+ Sbjct: 274 TNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 322 Score = 67.8 bits (164), Expect = 7e-11 Identities = 88/335 (26%), Positives = 114/335 (34%), Gaps = 72/335 (21%) Query: 445 ERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLP 504 +RPF+C CG RF K NL H + H + PH P C Sbjct: 233 DRPFQCACCGKRFRHKPNLIAHRRVHTGERPH-------------QCPECG--------- 270 Query: 505 PEKPVTTWLDSKPVLPTVPT-SVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSEC 563 K T +KP L + G + P + P+ S+ +R S Sbjct: 271 --KRFT----NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKR----SEGS 320 Query: 564 ASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTS 623 A +PG SPQ L GP + AEP P + P P Sbjct: 321 AQAAPGPG-----------SPQ-LPAGPQESAAEPT--PAVPLKPAQEPPPGAPPEHPQD 366 Query: 624 VDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSK----LQQLVENIDKKM---- 675 AP SL S + F L + Q T + + +N KK Sbjct: 367 PIEAPPSLYS------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVA 420 Query: 676 -------TDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGV 728 P C C R S S L H R H +RPF C CG+AF K L H + Sbjct: 421 HSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRI 480 Query: 729 HRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 H + P + CP C K F+ L H R+H G Sbjct: 481 HTGEKP----YVCPDCGKAFSQKSNLVSHRRIHTG 511 Score = 64.7 bits (156), Expect = 6e-10 Identities = 41/122 (33%), Positives = 50/122 (40%), Gaps = 14/122 (11%) Query: 354 AAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASA 413 AAPG SP LP P P V PL + G PP P+ Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAV----------PLKPAQEPPPGAPPE----HPQDPI 368 Query: 414 EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473 E P + C C + F + L+ H R HTGERPF C CG F K +L H + H + Sbjct: 369 EAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGE 428 Query: 474 YP 475 P Sbjct: 429 RP 430 Score = 63.2 bits (152), Expect = 2e-09 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 24/162 (14%) Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375 AAP P +P PQ +A+ + PA P PG P P+ + P Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEP------PPGAP----PEHPQDPIEAPP 372 Query: 376 PLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSAL 435 L S + L H++ + + E PF C C K FG + L Sbjct: 373 SLYSCDDCGRSFRLERFLRAHQR-----------QHTGERPF---TCAECGKNFGKKTHL 418 Query: 436 QIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 H R H+GERPF C CG RFS +L H + H P + Sbjct: 419 VAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFV 460 Score = 46.2 bits (108), Expect = 2e-04 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 1/89 (1%) Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738 ++C C R AL +H R P C CGR F L H VH A P + Sbjct: 57 HRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATP-DLG 115 Query: 739 HSCPICQKKFTNAVVLQQHIRMHMGGQIP 767 +C +C + F V L H+R H + P Sbjct: 116 FACHLCGQSFRGWVALVLHLRAHSAAKRP 144 Score = 42.0 bits (97), Expect = 0.004 Identities = 63/250 (25%), Positives = 77/250 (30%), Gaps = 73/250 (29%) Query: 294 RPESGASTPGGPAEPSAPAAP---SAAPAPAAP---APAPAPQSAASSQPQSASTPPALA 347 R E A GP P PA P +A P PA P A P P + PP+L Sbjct: 316 RSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLY 375 Query: 348 PGSLLGAAPGLPSPLL----------PQTSAS-GVIFPNP--LVSIAATANALDPL---- 390 G + L L P T A G F LV+ + + P Sbjct: 376 SCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEE 435 Query: 391 --------SALMKHRKGKPPNVSVFEP---KASAEDPFFK-----------HKCRFCAKV 428 S L HR+ P+ P KA P+ + C C K Sbjct: 436 CGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKA 495 Query: 429 FGSDSALQIHLRSHTGERP----------------------------FKCNICGNRFSTK 460 F S L H R HTGERP F C ICG F + Sbjct: 496 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 555 Query: 461 GNLKVHFQRH 470 L H ++H Sbjct: 556 ERLLAHQKKH 565 Score = 41.6 bits (96), Expect = 0.005 Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 24/157 (15%) Query: 892 GSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAP 951 GSP L A P P+ + P PE PQ+ E P S + G + Sbjct: 328 GSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQD---PIEAPPSLYSCDDCGRSF 384 Query: 952 G-----RAGIKE---EAPFSLLFLSRERGKCPSTV-------------CGVCGKPFACKS 990 RA ++ E PF+ + GK V C CG+ F+ S Sbjct: 385 RLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGS 444 Query: 991 ALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 L H R H +RPFVC C + L H H Sbjct: 445 HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 481 Score = 40.0 bits (92), Expect = 0.015 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHT-GERPFKCNICGNRFSTK 460 P +++ +A P C C + F AL +HLR+H+ +RP C C RF + Sbjct: 98 PFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRR 157 Query: 461 GNLKVHFQR 469 L+ H +R Sbjct: 158 KQLRAHLRR 166 Score = 39.3 bits (90), Expect = 0.025 Identities = 21/68 (30%), Positives = 29/68 (42%) Query: 410 KASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQR 469 ++ A+ P H+C C + F AL +H R P C CG RF L +H Q Sbjct: 47 QSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQV 106 Query: 470 HKEKYPHI 477 H P + Sbjct: 107 HAAATPDL 114 Score = 37.7 bits (86), Expect = 0.072 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%) Query: 681 CVICHRVLSCQSALKMHYRTHTG-ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 C +C + AL +H R H+ +RP C C R F + L+ H + R PP Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAH--LRRCHPPAPEAR 175 Query: 740 S--CPICQKKFTNAVVLQQHIRMHM 762 C C + F L H R+H+ Sbjct: 176 PFICGNCGRSFAQWDQLVAHKRVHV 200 Score = 35.8 bits (81), Expect = 0.27 Identities = 28/101 (27%), Positives = 35/101 (34%), Gaps = 12/101 (11%) Query: 1072 MALGEGPPLPAGVQVPAGPQTV---------MGPGLAPMLAPPPRRTPKQHNCQSCGKTF 1122 +A+G P PQT+ G +A A P R H C C + F Sbjct: 10 LAMGLAQPRLLSGPSQESPQTLGKESRGLRQQGTSVAQSGAQAPGRA---HRCAHCRRHF 66 Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 AL +H R P C CGR F L +H H Sbjct: 67 PGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH 107 Score = 35.8 bits (81), Expect = 0.27 Identities = 18/52 (34%), Positives = 24/52 (46%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729 P C C R S +S L H ++H + F C ICG+ F + L H H Sbjct: 514 PYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565 Score = 33.5 bits (75), Expect = 1.4 Identities = 16/49 (32%), Positives = 23/49 (46%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 C C + F+ KS L H +SH ++ F CA+C + L H H Sbjct: 517 CPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565 Score = 31.2 bits (69), Expect = 6.8 Identities = 35/125 (28%), Positives = 41/125 (32%), Gaps = 19/125 (15%) Query: 47 GEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPE------DFPEPSPA 100 GE C +C F H+R T + P P E P Sbjct: 260 GERPHQCPECGKRFTNKPYLTSHRRIHTG---------EKPYPCKECGRRFRHKPNLLSH 310 Query: 101 SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPA--PPTPA 158 S +R+E A G + A P E AEP A P A PPP AP P P Sbjct: 311 SKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPL--KPAQEPPPGAPPEHPQDPI 368 Query: 159 YGAPS 163 PS Sbjct: 369 EAPPS 373 >gi|153792647 replication initiator 1 isoform 3 [Homo sapiens] Length = 624 Score = 91.7 bits (226), Expect = 4e-18 Identities = 73/221 (33%), Positives = 93/221 (42%), Gaps = 27/221 (12%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037 C CGK F K L H R HT ERP C C + + L H H K P + Sbjct: 295 CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 354 Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMAL-GEGPP-LPAGVQVPAGPQTVMG 1095 F + P+L+S + K+ G A A G G P LPAG Q A T Sbjct: 355 GRRF-----RHKPNLLSHS-----KIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAV 404 Query: 1096 PGLAPMLAPPPRRTPKQ-----------HNCQSCGKTFSSASALQIHERTHTGEKPFGCT 1144 P L P PPP P+ ++C CG++F L+ H+R HTGE+PF C Sbjct: 405 P-LKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCA 463 Query: 1145 ICGRAFTTKGNLKVHMGTHMWNN--APARRGRRLSVENPMA 1183 CG+ F K +L H H A GRR S + +A Sbjct: 464 ECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA 504 Score = 85.5 bits (210), Expect = 3e-16 Identities = 101/386 (26%), Positives = 134/386 (34%), Gaps = 59/386 (15%) Query: 382 ATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRS 441 A A AL P R P V+ P A D F+ C C K F L H R Sbjct: 264 AAAKALGP-------RPRGRPAVTAPRPGGDAVDRPFQ--CACCGKRFRHKPNLIAHRRV 314 Query: 442 HTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGM 501 HTGERP +C CG RF+ K L H + H + P+ Sbjct: 315 HTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPY------------------------- 349 Query: 502 SLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASS 561 P K KP L L + G S A P SPQ P+ Sbjct: 350 ---PCKECGRRFRHKPNL--------LSHSKIHKRSEG---SAQAAPGPGSPQLPAGPQE 395 Query: 562 ECASLSPGLN---HVESGVSATAESPQSLLGGPP-LTKAEPVSLPCTNARAGDAPVGAQA 617 A +P + E A E PQ + PP L + R A Sbjct: 396 SAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHT 455 Query: 618 SAAPTSVDGAPTSLGSPG-LPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMT 676 P + + G L A S + PF + S+ S L D Sbjct: 456 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA--AHRRDHAPD 513 Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736 P C C + + L H R HTGE+P+ C CG+AF+ K NL +H +H + P Sbjct: 514 RPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERP-- 571 Query: 737 VQHSCPICQKKFTNAVVLQQHIRMHM 762 ++CP C + F+ L H + H+ Sbjct: 572 --YACPDCDRSFSQKSNLITHRKSHI 595 Score = 84.0 bits (206), Expect = 9e-16 Identities = 79/274 (28%), Positives = 96/274 (35%), Gaps = 54/274 (19%) Query: 901 SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960 S + AP G P A E +PLK PA P G P EA Sbjct: 374 SEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLK------PAQEPPPGAPPEHPQDPIEA 427 Query: 961 PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020 P SL C CG+ F + L H R HT ERPF CA C + Sbjct: 428 PPSLYS------------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGK---- 471 Query: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080 K HL+ H S + S E G+ + G Sbjct: 472 KTHLVAH-----------------------SRVHSGERPFACEEC---GRRFSQGSHLAA 505 Query: 1081 PAGVQVPAGPQTVMGPGLA----PMLAPPPR--RTPKQHNCQSCGKTFSSASALQIHERT 1134 P P G A P LA R K + C CGK FS S L H R Sbjct: 506 HRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRI 565 Query: 1135 HTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168 HTGE+P+ C C R+F+ K NL H +H+ + A Sbjct: 566 HTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 599 Score = 71.6 bits (174), Expect = 5e-12 Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 20/229 (8%) Query: 960 APFSLLFLSRERGKCPST--VCGVCGKPFACKSALEIHYRSHT-KERPFVCALCRRGCST 1016 APF L P C +CG+ F AL +H R+H+ +RP C C R Sbjct: 154 APFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWR 213 Query: 1017 MGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKM-EVNGHGKAMALG 1075 L+ HL R P+ P +S A + + E A ALG Sbjct: 214 RKQLRAHL---RRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALG 270 Query: 1076 EGPPLPAGVQVP-AGPQTVMGPGLAPMLAPPPRRTP------------KQHNCQSCGKTF 1122 P V P G V P R P + H C CGK F Sbjct: 271 PRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRF 330 Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPAR 1171 ++ L H R HTGEKP+ C CGR F K NL H H + A+ Sbjct: 331 TNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 379 Score = 67.8 bits (164), Expect = 7e-11 Identities = 88/335 (26%), Positives = 114/335 (34%), Gaps = 72/335 (21%) Query: 445 ERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLP 504 +RPF+C CG RF K NL H + H + PH P C Sbjct: 290 DRPFQCACCGKRFRHKPNLIAHRRVHTGERPH-------------QCPECG--------- 327 Query: 505 PEKPVTTWLDSKPVLPTVPT-SVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSEC 563 K T +KP L + G + P + P+ S+ +R S Sbjct: 328 --KRFT----NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKR----SEGS 377 Query: 564 ASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTS 623 A +PG SPQ L GP + AEP P + P P Sbjct: 378 AQAAPGPG-----------SPQ-LPAGPQESAAEPT--PAVPLKPAQEPPPGAPPEHPQD 423 Query: 624 VDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSK----LQQLVENIDKKM---- 675 AP SL S + F L + Q T + + +N KK Sbjct: 424 PIEAPPSLYS------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVA 477 Query: 676 -------TDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGV 728 P C C R S S L H R H +RPF C CG+AF K L H + Sbjct: 478 HSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRI 537 Query: 729 HRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 H + P + CP C K F+ L H R+H G Sbjct: 538 HTGEKP----YVCPDCGKAFSQKSNLVSHRRIHTG 568 Score = 64.7 bits (156), Expect = 6e-10 Identities = 41/122 (33%), Positives = 50/122 (40%), Gaps = 14/122 (11%) Query: 354 AAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASA 413 AAPG SP LP P P V PL + G PP P+ Sbjct: 380 AAPGPGSPQLPAGPQESAAEPTPAV----------PLKPAQEPPPGAPPE----HPQDPI 425 Query: 414 EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473 E P + C C + F + L+ H R HTGERPF C CG F K +L H + H + Sbjct: 426 EAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGE 485 Query: 474 YP 475 P Sbjct: 486 RP 487 Score = 63.2 bits (152), Expect = 2e-09 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 24/162 (14%) Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375 AAP P +P PQ +A+ + PA P PG P P+ + P Sbjct: 380 AAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEP------PPGAP----PEHPQDPIEAPP 429 Query: 376 PLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSAL 435 L S + L H++ + + E PF C C K FG + L Sbjct: 430 SLYSCDDCGRSFRLERFLRAHQR-----------QHTGERPF---TCAECGKNFGKKTHL 475 Query: 436 QIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 H R H+GERPF C CG RFS +L H + H P + Sbjct: 476 VAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFV 517 Score = 46.2 bits (108), Expect = 2e-04 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 1/89 (1%) Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738 ++C C R AL +H R P C CGR F L H VH A P + Sbjct: 114 HRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATP-DLG 172 Query: 739 HSCPICQKKFTNAVVLQQHIRMHMGGQIP 767 +C +C + F V L H+R H + P Sbjct: 173 FACHLCGQSFRGWVALVLHLRAHSAAKRP 201 Score = 42.0 bits (97), Expect = 0.004 Identities = 63/250 (25%), Positives = 77/250 (30%), Gaps = 73/250 (29%) Query: 294 RPESGASTPGGPAEPSAPAAP---SAAPAPAAP---APAPAPQSAASSQPQSASTPPALA 347 R E A GP P PA P +A P PA P A P P + PP+L Sbjct: 373 RSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLY 432 Query: 348 PGSLLGAAPGLPSPLL----------PQTSAS-GVIFPNP--LVSIAATANALDPL---- 390 G + L L P T A G F LV+ + + P Sbjct: 433 SCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEE 492 Query: 391 --------SALMKHRKGKPPNVSVFEP---KASAEDPFFK-----------HKCRFCAKV 428 S L HR+ P+ P KA P+ + C C K Sbjct: 493 CGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKA 552 Query: 429 FGSDSALQIHLRSHTGERP----------------------------FKCNICGNRFSTK 460 F S L H R HTGERP F C ICG F + Sbjct: 553 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 612 Query: 461 GNLKVHFQRH 470 L H ++H Sbjct: 613 ERLLAHQKKH 622 Score = 41.6 bits (96), Expect = 0.005 Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 24/157 (15%) Query: 892 GSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAP 951 GSP L A P P+ + P PE PQ+ E P S + G + Sbjct: 385 GSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQD---PIEAPPSLYSCDDCGRSF 441 Query: 952 G-----RAGIKE---EAPFSLLFLSRERGKCPSTV-------------CGVCGKPFACKS 990 RA ++ E PF+ + GK V C CG+ F+ S Sbjct: 442 RLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGS 501 Query: 991 ALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 L H R H +RPFVC C + L H H Sbjct: 502 HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 538 Score = 40.0 bits (92), Expect = 0.015 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHT-GERPFKCNICGNRFSTK 460 P +++ +A P C C + F AL +HLR+H+ +RP C C RF + Sbjct: 155 PFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRR 214 Query: 461 GNLKVHFQR 469 L+ H +R Sbjct: 215 KQLRAHLRR 223 Score = 39.3 bits (90), Expect = 0.025 Identities = 21/68 (30%), Positives = 29/68 (42%) Query: 410 KASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQR 469 ++ A+ P H+C C + F AL +H R P C CG RF L +H Q Sbjct: 104 QSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQV 163 Query: 470 HKEKYPHI 477 H P + Sbjct: 164 HAAATPDL 171 Score = 37.7 bits (86), Expect = 0.072 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%) Query: 681 CVICHRVLSCQSALKMHYRTHTG-ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 C +C + AL +H R H+ +RP C C R F + L+ H + R PP Sbjct: 175 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAH--LRRCHPPAPEAR 232 Query: 740 S--CPICQKKFTNAVVLQQHIRMHM 762 C C + F L H R+H+ Sbjct: 233 PFICGNCGRSFAQWDQLVAHKRVHV 257 Score = 36.2 bits (82), Expect = 0.21 Identities = 34/123 (27%), Positives = 42/123 (34%), Gaps = 13/123 (10%) Query: 1050 PSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTV---------MGPGLAP 1100 P L S A +E G +A+G P PQT+ G +A Sbjct: 46 PQLCSLQAEEEPMLERRCRGP-LAMGLAQPRLLSGPSQESPQTLGKESRGLRQQGTSVAQ 104 Query: 1101 MLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHM 1160 A P R H C C + F AL +H R P C CGR F L +H Sbjct: 105 SGAQAPGRA---HRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHR 161 Query: 1161 GTH 1163 H Sbjct: 162 QVH 164 Score = 35.8 bits (81), Expect = 0.27 Identities = 18/52 (34%), Positives = 24/52 (46%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729 P C C R S +S L H ++H + F C ICG+ F + L H H Sbjct: 571 PYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 622 Score = 33.5 bits (75), Expect = 1.4 Identities = 16/49 (32%), Positives = 23/49 (46%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 C C + F+ KS L H +SH ++ F CA+C + L H H Sbjct: 574 CPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 622 Score = 31.2 bits (69), Expect = 6.8 Identities = 35/125 (28%), Positives = 41/125 (32%), Gaps = 19/125 (15%) Query: 47 GEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPE------DFPEPSPA 100 GE C +C F H+R T + P P E P Sbjct: 317 GERPHQCPECGKRFTNKPYLTSHRRIHTG---------EKPYPCKECGRRFRHKPNLLSH 367 Query: 101 SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPA--PPTPA 158 S +R+E A G + A P E AEP A P A PPP AP P P Sbjct: 368 SKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPL--KPAQEPPPGAPPEHPQDPI 425 Query: 159 YGAPS 163 PS Sbjct: 426 EAPPS 430 >gi|153791994 replication initiator 1 isoform 1 [Homo sapiens] Length = 567 Score = 91.7 bits (226), Expect = 4e-18 Identities = 73/221 (33%), Positives = 93/221 (42%), Gaps = 27/221 (12%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLF 1037 C CGK F K L H R HT ERP C C + + L H H K P + Sbjct: 238 CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 297 Query: 1038 DPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMAL-GEGPP-LPAGVQVPAGPQTVMG 1095 F + P+L+S + K+ G A A G G P LPAG Q A T Sbjct: 298 GRRF-----RHKPNLLSHS-----KIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAV 347 Query: 1096 PGLAPMLAPPPRRTPKQ-----------HNCQSCGKTFSSASALQIHERTHTGEKPFGCT 1144 P L P PPP P+ ++C CG++F L+ H+R HTGE+PF C Sbjct: 348 P-LKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCA 406 Query: 1145 ICGRAFTTKGNLKVHMGTHMWNN--APARRGRRLSVENPMA 1183 CG+ F K +L H H A GRR S + +A Sbjct: 407 ECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA 447 Score = 85.5 bits (210), Expect = 3e-16 Identities = 101/386 (26%), Positives = 134/386 (34%), Gaps = 59/386 (15%) Query: 382 ATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRS 441 A A AL P R P V+ P A D F+ C C K F L H R Sbjct: 207 AAAKALGP-------RPRGRPAVTAPRPGGDAVDRPFQ--CACCGKRFRHKPNLIAHRRV 257 Query: 442 HTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGM 501 HTGERP +C CG RF+ K L H + H + P+ Sbjct: 258 HTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPY------------------------- 292 Query: 502 SLPPEKPVTTWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASS 561 P K KP L L + G S A P SPQ P+ Sbjct: 293 ---PCKECGRRFRHKPNL--------LSHSKIHKRSEG---SAQAAPGPGSPQLPAGPQE 338 Query: 562 ECASLSPGLN---HVESGVSATAESPQSLLGGPP-LTKAEPVSLPCTNARAGDAPVGAQA 617 A +P + E A E PQ + PP L + R A Sbjct: 339 SAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHT 398 Query: 618 SAAPTSVDGAPTSLGSPG-LPAVSEQFKAQFPFGGLLDSMQTSETSKLQQLVENIDKKMT 676 P + + G L A S + PF + S+ S L D Sbjct: 399 GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLA--AHRRDHAPD 456 Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736 P C C + + L H R HTGE+P+ C CG+AF+ K NL +H +H + P Sbjct: 457 RPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERP-- 514 Query: 737 VQHSCPICQKKFTNAVVLQQHIRMHM 762 ++CP C + F+ L H + H+ Sbjct: 515 --YACPDCDRSFSQKSNLITHRKSHI 538 Score = 84.0 bits (206), Expect = 9e-16 Identities = 79/274 (28%), Positives = 96/274 (35%), Gaps = 54/274 (19%) Query: 901 SSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAPGRAGIKEEA 960 S + AP G P A E +PLK PA P G P EA Sbjct: 317 SEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLK------PAQEPPPGAPPEHPQDPIEA 370 Query: 961 PFSLLFLSRERGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNL 1020 P SL C CG+ F + L H R HT ERPF CA C + Sbjct: 371 PPSLYS------------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGK---- 414 Query: 1021 KQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPL 1080 K HL+ H S + S E G+ + G Sbjct: 415 KTHLVAH-----------------------SRVHSGERPFACEEC---GRRFSQGSHLAA 448 Query: 1081 PAGVQVPAGPQTVMGPGLA----PMLAPPPR--RTPKQHNCQSCGKTFSSASALQIHERT 1134 P P G A P LA R K + C CGK FS S L H R Sbjct: 449 HRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRI 508 Query: 1135 HTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNA 1168 HTGE+P+ C C R+F+ K NL H +H+ + A Sbjct: 509 HTGERPYACPDCDRSFSQKSNLITHRKSHIRDGA 542 Score = 71.6 bits (174), Expect = 5e-12 Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 20/229 (8%) Query: 960 APFSLLFLSRERGKCPST--VCGVCGKPFACKSALEIHYRSHT-KERPFVCALCRRGCST 1016 APF L P C +CG+ F AL +H R+H+ +RP C C R Sbjct: 97 APFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWR 156 Query: 1017 MGNLKQHLLTHRLKELPSQLFDPNFALGPSQSTPSLISSAAPTMIKM-EVNGHGKAMALG 1075 L+ HL R P+ P +S A + + E A ALG Sbjct: 157 RKQLRAHL---RRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALG 213 Query: 1076 EGPPLPAGVQVP-AGPQTVMGPGLAPMLAPPPRRTP------------KQHNCQSCGKTF 1122 P V P G V P R P + H C CGK F Sbjct: 214 PRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRF 273 Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPAR 1171 ++ L H R HTGEKP+ C CGR F K NL H H + A+ Sbjct: 274 TNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 322 Score = 67.8 bits (164), Expect = 7e-11 Identities = 88/335 (26%), Positives = 114/335 (34%), Gaps = 72/335 (21%) Query: 445 ERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLP 504 +RPF+C CG RF K NL H + H + PH P C Sbjct: 233 DRPFQCACCGKRFRHKPNLIAHRRVHTGERPH-------------QCPECG--------- 270 Query: 505 PEKPVTTWLDSKPVLPTVPT-SVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSEC 563 K T +KP L + G + P + P+ S+ +R S Sbjct: 271 --KRFT----NKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKR----SEGS 320 Query: 564 ASLSPGLNHVESGVSATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQASAAPTS 623 A +PG SPQ L GP + AEP P + P P Sbjct: 321 AQAAPGPG-----------SPQ-LPAGPQESAAEPT--PAVPLKPAQEPPPGAPPEHPQD 366 Query: 624 VDGAPTSLGSPGLPAVSEQFKAQFPFGGLLDSMQTSETSK----LQQLVENIDKKM---- 675 AP SL S + F L + Q T + + +N KK Sbjct: 367 PIEAPPSLYS------CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVA 420 Query: 676 -------TDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGV 728 P C C R S S L H R H +RPF C CG+AF K L H + Sbjct: 421 HSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRI 480 Query: 729 HRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 H + P + CP C K F+ L H R+H G Sbjct: 481 HTGEKP----YVCPDCGKAFSQKSNLVSHRRIHTG 511 Score = 64.7 bits (156), Expect = 6e-10 Identities = 41/122 (33%), Positives = 50/122 (40%), Gaps = 14/122 (11%) Query: 354 AAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASA 413 AAPG SP LP P P V PL + G PP P+ Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAV----------PLKPAQEPPPGAPPE----HPQDPI 368 Query: 414 EDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473 E P + C C + F + L+ H R HTGERPF C CG F K +L H + H + Sbjct: 369 EAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGE 428 Query: 474 YP 475 P Sbjct: 429 RP 430 Score = 63.2 bits (152), Expect = 2e-09 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 24/162 (14%) Query: 316 AAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPN 375 AAP P +P PQ +A+ + PA P PG P P+ + P Sbjct: 323 AAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEP------PPGAP----PEHPQDPIEAPP 372 Query: 376 PLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSAL 435 L S + L H++ + + E PF C C K FG + L Sbjct: 373 SLYSCDDCGRSFRLERFLRAHQR-----------QHTGERPF---TCAECGKNFGKKTHL 418 Query: 436 QIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHI 477 H R H+GERPF C CG RFS +L H + H P + Sbjct: 419 VAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFV 460 Score = 46.2 bits (108), Expect = 2e-04 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 1/89 (1%) Query: 679 NQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQ 738 ++C C R AL +H R P C CGR F L H VH A P + Sbjct: 57 HRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATP-DLG 115 Query: 739 HSCPICQKKFTNAVVLQQHIRMHMGGQIP 767 +C +C + F V L H+R H + P Sbjct: 116 FACHLCGQSFRGWVALVLHLRAHSAAKRP 144 Score = 42.0 bits (97), Expect = 0.004 Identities = 63/250 (25%), Positives = 77/250 (30%), Gaps = 73/250 (29%) Query: 294 RPESGASTPGGPAEPSAPAAP---SAAPAPAAP---APAPAPQSAASSQPQSASTPPALA 347 R E A GP P PA P +A P PA P A P P + PP+L Sbjct: 316 RSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLY 375 Query: 348 PGSLLGAAPGLPSPLL----------PQTSAS-GVIFPNP--LVSIAATANALDPL---- 390 G + L L P T A G F LV+ + + P Sbjct: 376 SCDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEE 435 Query: 391 --------SALMKHRKGKPPNVSVFEP---KASAEDPFFK-----------HKCRFCAKV 428 S L HR+ P+ P KA P+ + C C K Sbjct: 436 CGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKA 495 Query: 429 FGSDSALQIHLRSHTGERP----------------------------FKCNICGNRFSTK 460 F S L H R HTGERP F C ICG F + Sbjct: 496 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 555 Query: 461 GNLKVHFQRH 470 L H ++H Sbjct: 556 ERLLAHQKKH 565 Score = 41.6 bits (96), Expect = 0.005 Identities = 42/157 (26%), Positives = 55/157 (35%), Gaps = 24/157 (15%) Query: 892 GSPALSESSSSQALSPAPSNGESFRSKSPGLGAPEEPQEIPLKTERPDSPAAAPGSGGAP 951 GSP L A P P+ + P PE PQ+ E P S + G + Sbjct: 328 GSPQLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQD---PIEAPPSLYSCDDCGRSF 384 Query: 952 G-----RAGIKE---EAPFSLLFLSRERGKCPSTV-------------CGVCGKPFACKS 990 RA ++ E PF+ + GK V C CG+ F+ S Sbjct: 385 RLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGS 444 Query: 991 ALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 L H R H +RPFVC C + L H H Sbjct: 445 HLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH 481 Score = 40.0 bits (92), Expect = 0.015 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 402 PNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHT-GERPFKCNICGNRFSTK 460 P +++ +A P C C + F AL +HLR+H+ +RP C C RF + Sbjct: 98 PFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRR 157 Query: 461 GNLKVHFQR 469 L+ H +R Sbjct: 158 KQLRAHLRR 166 Score = 39.3 bits (90), Expect = 0.025 Identities = 21/68 (30%), Positives = 29/68 (42%) Query: 410 KASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQR 469 ++ A+ P H+C C + F AL +H R P C CG RF L +H Q Sbjct: 47 QSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQV 106 Query: 470 HKEKYPHI 477 H P + Sbjct: 107 HAAATPDL 114 Score = 37.7 bits (86), Expect = 0.072 Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 5/85 (5%) Query: 681 CVICHRVLSCQSALKMHYRTHTG-ERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 C +C + AL +H R H+ +RP C C R F + L+ H + R PP Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAH--LRRCHPPAPEAR 175 Query: 740 S--CPICQKKFTNAVVLQQHIRMHM 762 C C + F L H R+H+ Sbjct: 176 PFICGNCGRSFAQWDQLVAHKRVHV 200 Score = 35.8 bits (81), Expect = 0.27 Identities = 28/101 (27%), Positives = 35/101 (34%), Gaps = 12/101 (11%) Query: 1072 MALGEGPPLPAGVQVPAGPQTV---------MGPGLAPMLAPPPRRTPKQHNCQSCGKTF 1122 +A+G P PQT+ G +A A P R H C C + F Sbjct: 10 LAMGLAQPRLLSGPSQESPQTLGKESRGLRQQGTSVAQSGAQAPGRA---HRCAHCRRHF 66 Query: 1123 SSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTH 1163 AL +H R P C CGR F L +H H Sbjct: 67 PGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH 107 Score = 35.8 bits (81), Expect = 0.27 Identities = 18/52 (34%), Positives = 24/52 (46%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVH 729 P C C R S +S L H ++H + F C ICG+ F + L H H Sbjct: 514 PYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565 Score = 33.5 bits (75), Expect = 1.4 Identities = 16/49 (32%), Positives = 23/49 (46%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTH 1027 C C + F+ KS L H +SH ++ F CA+C + L H H Sbjct: 517 CPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565 Score = 31.2 bits (69), Expect = 6.8 Identities = 35/125 (28%), Positives = 41/125 (32%), Gaps = 19/125 (15%) Query: 47 GEETSVCEKCCAEFFKWADFLEHQRSCTKLPPVLIVHEDAPAPPPE------DFPEPSPA 100 GE C +C F H+R T + P P E P Sbjct: 260 GERPHQCPECGKRFTNKPYLTSHRRIHTG---------EKPYPCKECGRRFRHKPNLLSH 310 Query: 101 SSPSERAESEAAEEAGAEGAEGEARPVEKEAEPMDAEPAGDTRAPRPPPAAPA--PPTPA 158 S +R+E A G + A P E AEP A P A PPP AP P P Sbjct: 311 SKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPL--KPAQEPPPGAPPEHPQDPI 368 Query: 159 YGAPS 163 PS Sbjct: 369 EAPPS 373 >gi|37622343 zinc finger protein 266 [Homo sapiens] Length = 549 Score = 90.5 bits (223), Expect = 9e-18 Identities = 62/187 (33%), Positives = 84/187 (44%), Gaps = 28/187 (14%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK FA S L H R+HT E+PF C C + + NL HL H E P + + Sbjct: 382 CKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHT-GEKPFECLE 440 Query: 1039 PNFALGPSQSTPSLIS--SAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP 1096 A S S + + SA ME GKA P V + T Sbjct: 441 CGKAFTHSSSLNNHMRTHSAKKPFTCMEC---GKAFKF------PTCVNLHMRIHT---- 487 Query: 1097 GLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNL 1156 K + C+ CGK+FS +++ Q+HERTHTGEKP+ C CG+AF++ + Sbjct: 488 ------------GEKPYKCKQCGKSFSYSNSFQLHERTHTGEKPYECKECGKAFSSSSSF 535 Query: 1157 KVHMGTH 1163 + H H Sbjct: 536 RNHERRH 542 Score = 85.5 bits (210), Expect = 3e-16 Identities = 58/192 (30%), Positives = 82/192 (42%), Gaps = 10/192 (5%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F L H ++HT E+P+ C C R + L QH+ H + E P + + Sbjct: 242 CKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIH-VGEKPYECKE 300 Query: 1039 PNFAL-GPSQSTPSLISSAAPTMIKMEVNGHG--KAMALGEGPPLPAGVQ----VPAGPQ 1091 A SQ T L + A + ++ G + L + + G++ G Sbjct: 301 CGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKA 360 Query: 1092 TVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151 L P + C+ CGK F+ +S L H RTHTGEKPF C CG+AF Sbjct: 361 FTQNSDLTKHARTHSGERP--YECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFA 418 Query: 1152 TKGNLKVHMGTH 1163 NL H+ H Sbjct: 419 ISSNLSGHLRIH 430 Score = 73.2 bits (178), Expect = 2e-12 Identities = 37/103 (35%), Positives = 52/103 (50%), Gaps = 5/103 (4%) Query: 662 SKLQQLVENIDKKMT-DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720 ++ QL E++ DP +C IC + S L H+R HTG +P+KCK CG+AFT Sbjct: 306 TRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKAFTQNS 365 Query: 721 NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 +L H H + P + C C K F + L +H R H G Sbjct: 366 DLTKHARTHSGERP----YECKECGKAFARSSRLSEHTRTHTG 404 Score = 71.6 bits (174), Expect = 5e-12 Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +CV C + + S L H R HTGE+PF+C CG+AFT +L H H AK P Sbjct: 407 PFECVKCGKAFAISSNLSGHLRIHTGEKPFECLECGKAFTHSSSLNNHMRTHSAKKPF-- 464 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 +C C K F + H+R+H G Sbjct: 465 --TCMECGKAFKFPTCVNLHMRIHTG 488 Score = 71.2 bits (173), Expect = 6e-12 Identities = 33/84 (39%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + S L H RTHTGE+PF+C CG+AF NL H +H + P Sbjct: 379 PYECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHTGEKPF-- 436 Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761 C C K FT++ L H+R H Sbjct: 437 --ECLECGKAFTHSSSLNNHMRTH 458 Score = 69.7 bits (169), Expect = 2e-11 Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 24/111 (21%) Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736 +P +C C + + L H +THTGE+P+KCK CGRAFT L H +H + P Sbjct: 238 NPYECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIHVGEKPYE 297 Query: 737 VQH------------------------SCPICQKKFTNAVVLQQHIRMHMG 763 + C IC K F N+ L H R+H G Sbjct: 298 CKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTG 348 Score = 66.6 bits (161), Expect = 1e-10 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + S L H RTH+GERP++CK CG+AF L H H + P Sbjct: 351 PYKCKDCGKAFTQNSDLTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTGEKPF-- 408 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 C C K F + L H+R+H G Sbjct: 409 --ECVKCGKAFAISSNLSGHLRIHTG 432 Score = 65.9 bits (159), Expect = 2e-10 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + L +H THTG+ P++CK CG+AFT L H H + P Sbjct: 211 PYKCKECGKGFRYSAYLNIHMGTHTGDNPYECKECGKAFTRSCQLTQHRKTHTGEKP--- 267 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C + FT + L QH+++H+G Sbjct: 268 -YKCKDCGRAFTVSSCLSQHMKIHVG 292 Score = 65.5 bits (158), Expect = 3e-10 Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S L H +THT + PF+CKICG++F L HF +H P Sbjct: 295 PYECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKP--- 351 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K FT L +H R H G Sbjct: 352 -YKCKDCGKAFTQNSDLTKHARTHSG 376 Score = 63.5 bits (153), Expect = 1e-09 Identities = 52/193 (26%), Positives = 77/193 (39%), Gaps = 35/193 (18%) Query: 977 TVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQL 1036 +V CGK F+ + + R+ T E+ F C+ + +L+ HL TH + L Sbjct: 129 SVFSQCGKAFSLNPDV-VCQRTCTGEKAFDCSDSGKSFINHSHLQGHLRTHNGESLHEW- 186 Query: 1037 FDPNFALGPSQSTPSLISSAAPTMIKMEVNGHG-----KAMALGEGPPLPAGVQVPAGPQ 1091 + I S T + + + H K G+G A + + G Sbjct: 187 ---------KECGRGFIHS---TDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTH 234 Query: 1092 TVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151 T P + C+ CGK F+ + L H +THTGEKP+ C CGRAFT Sbjct: 235 TGDNP----------------YECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFT 278 Query: 1152 TKGNLKVHMGTHM 1164 L HM H+ Sbjct: 279 VSSCLSQHMKIHV 291 Score = 62.4 bits (150), Expect = 3e-09 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C+ C + + + +H R HTGE+P+KCK CG++F+ + + H H + P Sbjct: 463 PFTCMECGKAFKFPTCVNLHMRIHTGEKPYKCKQCGKSFSYSNSFQLHERTHTGEKP--- 519 Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761 + C C K F+++ + H R H Sbjct: 520 -YECKECGKAFSSSSSFRNHERRH 542 Score = 60.1 bits (144), Expect = 1e-08 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C+ C + + S+L H RTH+ ++PF C CG+AF + H +H + P Sbjct: 435 PFECLECGKAFTHSSSLNNHMRTHSAKKPFTCMECGKAFKFPTCVNLHMRIHTGEKP--- 491 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + Q H R H G Sbjct: 492 -YKCKQCGKSFSYSNSFQLHERTHTG 516 Score = 58.5 bits (140), Expect = 4e-08 Identities = 21/54 (38%), Positives = 36/54 (66%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473 +KC+ C K F ++ Q+H R+HTGE+P++C CG FS+ + + H +RH ++ Sbjct: 492 YKCKQCGKSFSYSNSFQLHERTHTGEKPYECKECGKAFSSSSSFRNHERRHADE 545 Score = 57.4 bits (137), Expect = 9e-08 Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 4/80 (5%) Query: 684 CHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPI 743 C R + L + +TH E+P+KCK CG+ F L H G H P + C Sbjct: 189 CGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDNP----YECKE 244 Query: 744 CQKKFTNAVVLQQHIRMHMG 763 C K FT + L QH + H G Sbjct: 245 CGKAFTRSCQLTQHRKTHTG 264 Score = 57.4 bits (137), Expect = 9e-08 Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 +A+DPF +C+ C K F + S L H R HTG +P+KC CG F+ +L H + H Sbjct: 319 TAKDPF---ECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKAFTQNSDLTKHARTHS 375 Query: 472 EKYPH 476 + P+ Sbjct: 376 GERPY 380 Score = 56.6 bits (135), Expect = 2e-07 Identities = 26/64 (40%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 S E P+ +C+ C K F S L H R+HTGE+PF+C CG F+ NL H + H Sbjct: 375 SGERPY---ECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHT 431 Query: 472 EKYP 475 + P Sbjct: 432 GEKP 435 Score = 55.8 bits (133), Expect = 3e-07 Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 SA+ PF C C K F + + +H+R HTGE+P+KC CG FS + ++H + H Sbjct: 459 SAKKPF---TCMECGKAFKFPTCVNLHMRIHTGEKPYKCKQCGKSFSYSNSFQLHERTHT 515 Query: 472 EKYPH 476 + P+ Sbjct: 516 GEKPY 520 Score = 55.5 bits (132), Expect = 3e-07 Identities = 27/64 (42%), Positives = 34/64 (53%), Gaps = 3/64 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + E PF +C C K F S L HLR HTGE+PF+C CG F+ +L H + H Sbjct: 403 TGEKPF---ECVKCGKAFAISSNLSGHLRIHTGEKPFECLECGKAFTHSSSLNNHMRTHS 459 Query: 472 EKYP 475 K P Sbjct: 460 AKKP 463 Score = 54.7 bits (130), Expect = 6e-07 Identities = 22/56 (39%), Positives = 32/56 (57%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475 +KC+ C K F +S L H R+H+GERP++C CG F+ L H + H + P Sbjct: 352 YKCKDCGKAFTQNSDLTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTGEKP 407 Score = 52.8 bits (125), Expect = 2e-06 Identities = 21/55 (38%), Positives = 31/55 (56%) Query: 1113 HNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNN 1167 H + CG+ F ++ L + +TH EKP+ C CG+ F L +HMGTH +N Sbjct: 184 HEWKECGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDN 238 Score = 51.6 bits (122), Expect = 5e-06 Identities = 20/56 (35%), Positives = 30/56 (53%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475 +KC+ C + F S L H++ H GE+P++C CG F+ L H + H K P Sbjct: 268 YKCKDCGRAFTVSSCLSQHMKIHVGEKPYECKECGIAFTRSSQLTEHLKTHTAKDP 323 Score = 50.8 bits (120), Expect = 8e-06 Identities = 20/57 (35%), Positives = 31/57 (54%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F L H ++HTGE+P+KC CG F+ L H + H + P+ Sbjct: 240 YECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIHVGEKPY 296 Score = 50.1 bits (118), Expect = 1e-05 Identities = 20/57 (35%), Positives = 32/57 (56%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F + L IH+ +HTG+ P++C CG F+ L H + H + P+ Sbjct: 212 YKCKECGKGFRYSAYLNIHMGTHTGDNPYECKECGKAFTRSCQLTQHRKTHTGEKPY 268 Score = 48.9 bits (115), Expect = 3e-05 Identities = 21/57 (36%), Positives = 30/57 (52%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C F S L HL++HT + PF+C ICG F L HF+ H P+ Sbjct: 296 YECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPY 352 Score = 46.6 bits (109), Expect = 2e-04 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + E PF +C C K F S+L H+R+H+ ++PF C CG F + +H + H Sbjct: 431 TGEKPF---ECLECGKAFTHSSSLNNHMRTHSAKKPFTCMECGKAFKFPTCVNLHMRIHT 487 Query: 472 EKYPH 476 + P+ Sbjct: 488 GEKPY 492 Score = 41.6 bits (96), Expect = 0.005 Identities = 16/57 (28%), Positives = 28/57 (49%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 H+ + C + F + L + +++H E+P+KC CG F L +H H P+ Sbjct: 184 HEWKECGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDNPY 240 Score = 38.1 bits (87), Expect = 0.055 Identities = 20/55 (36%), Positives = 27/55 (49%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 C K F + S LQ HLR+H GE + CG F +L V Q H+ + P+ Sbjct: 158 CSDSGKSFINHSHLQGHLRTHNGESLHEWKECGRGFIHSTDLAVRIQTHRSEKPY 212 Score = 36.6 bits (83), Expect = 0.16 Identities = 37/129 (28%), Positives = 52/129 (40%), Gaps = 23/129 (17%) Query: 654 DSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICG 713 D + +S +Q + + +++D QC V S S LK H RT E F+C + G Sbjct: 56 DVLGEPTSSGIQMIGSHNGGEVSDVKQC---GDVSSEHSCLKTHVRTQNSENTFECYLYG 112 Query: 714 RAFTTKGNLKTHFGVHRA-----------KPPLRVQHSCP-----ICQ---KKFTNAVVL 754 F T + KT G R+ P + Q +C C K F N L Sbjct: 113 VDFLTL-HKKTSTGEQRSVFSQCGKAFSLNPDVVCQRTCTGEKAFDCSDSGKSFINHSHL 171 Query: 755 QQHIRMHMG 763 Q H+R H G Sbjct: 172 QGHLRTHNG 180 >gi|37622349 zinc finger protein 266 [Homo sapiens] Length = 549 Score = 90.5 bits (223), Expect = 9e-18 Identities = 62/187 (33%), Positives = 84/187 (44%), Gaps = 28/187 (14%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK FA S L H R+HT E+PF C C + + NL HL H E P + + Sbjct: 382 CKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHT-GEKPFECLE 440 Query: 1039 PNFALGPSQSTPSLIS--SAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTVMGP 1096 A S S + + SA ME GKA P V + T Sbjct: 441 CGKAFTHSSSLNNHMRTHSAKKPFTCMEC---GKAFKF------PTCVNLHMRIHT---- 487 Query: 1097 GLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNL 1156 K + C+ CGK+FS +++ Q+HERTHTGEKP+ C CG+AF++ + Sbjct: 488 ------------GEKPYKCKQCGKSFSYSNSFQLHERTHTGEKPYECKECGKAFSSSSSF 535 Query: 1157 KVHMGTH 1163 + H H Sbjct: 536 RNHERRH 542 Score = 85.5 bits (210), Expect = 3e-16 Identities = 58/192 (30%), Positives = 82/192 (42%), Gaps = 10/192 (5%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQLFD 1038 C CGK F L H ++HT E+P+ C C R + L QH+ H + E P + + Sbjct: 242 CKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIH-VGEKPYECKE 300 Query: 1039 PNFAL-GPSQSTPSLISSAAPTMIKMEVNGHG--KAMALGEGPPLPAGVQ----VPAGPQ 1091 A SQ T L + A + ++ G + L + + G++ G Sbjct: 301 CGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKA 360 Query: 1092 TVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151 L P + C+ CGK F+ +S L H RTHTGEKPF C CG+AF Sbjct: 361 FTQNSDLTKHARTHSGERP--YECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFA 418 Query: 1152 TKGNLKVHMGTH 1163 NL H+ H Sbjct: 419 ISSNLSGHLRIH 430 Score = 73.2 bits (178), Expect = 2e-12 Identities = 37/103 (35%), Positives = 52/103 (50%), Gaps = 5/103 (4%) Query: 662 SKLQQLVENIDKKMT-DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKG 720 ++ QL E++ DP +C IC + S L H+R HTG +P+KCK CG+AFT Sbjct: 306 TRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKAFTQNS 365 Query: 721 NLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 +L H H + P + C C K F + L +H R H G Sbjct: 366 DLTKHARTHSGERP----YECKECGKAFARSSRLSEHTRTHTG 404 Score = 71.6 bits (174), Expect = 5e-12 Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +CV C + + S L H R HTGE+PF+C CG+AFT +L H H AK P Sbjct: 407 PFECVKCGKAFAISSNLSGHLRIHTGEKPFECLECGKAFTHSSSLNNHMRTHSAKKPF-- 464 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 +C C K F + H+R+H G Sbjct: 465 --TCMECGKAFKFPTCVNLHMRIHTG 488 Score = 71.2 bits (173), Expect = 6e-12 Identities = 33/84 (39%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + S L H RTHTGE+PF+C CG+AF NL H +H + P Sbjct: 379 PYECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHTGEKPF-- 436 Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761 C C K FT++ L H+R H Sbjct: 437 --ECLECGKAFTHSSSLNNHMRTH 458 Score = 69.7 bits (169), Expect = 2e-11 Identities = 35/111 (31%), Positives = 47/111 (42%), Gaps = 24/111 (21%) Query: 677 DPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLR 736 +P +C C + + L H +THTGE+P+KCK CGRAFT L H +H + P Sbjct: 238 NPYECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIHVGEKPYE 297 Query: 737 VQH------------------------SCPICQKKFTNAVVLQQHIRMHMG 763 + C IC K F N+ L H R+H G Sbjct: 298 CKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTG 348 Score = 66.6 bits (161), Expect = 1e-10 Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + S L H RTH+GERP++CK CG+AF L H H + P Sbjct: 351 PYKCKDCGKAFTQNSDLTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTGEKPF-- 408 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 C C K F + L H+R+H G Sbjct: 409 --ECVKCGKAFAISSNLSGHLRIHTG 432 Score = 65.9 bits (159), Expect = 2e-10 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + + L +H THTG+ P++CK CG+AFT L H H + P Sbjct: 211 PYKCKECGKGFRYSAYLNIHMGTHTGDNPYECKECGKAFTRSCQLTQHRKTHTGEKP--- 267 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C + FT + L QH+++H+G Sbjct: 268 -YKCKDCGRAFTVSSCLSQHMKIHVG 292 Score = 65.5 bits (158), Expect = 3e-10 Identities = 32/86 (37%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C C + S L H +THT + PF+CKICG++F L HF +H P Sbjct: 295 PYECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKP--- 351 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K FT L +H R H G Sbjct: 352 -YKCKDCGKAFTQNSDLTKHARTHSG 376 Score = 63.5 bits (153), Expect = 1e-09 Identities = 52/193 (26%), Positives = 77/193 (39%), Gaps = 35/193 (18%) Query: 977 TVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELPSQL 1036 +V CGK F+ + + R+ T E+ F C+ + +L+ HL TH + L Sbjct: 129 SVFSQCGKAFSLNPDV-VCQRTCTGEKAFDCSDSGKSFINHSHLQGHLRTHNGESLHEW- 186 Query: 1037 FDPNFALGPSQSTPSLISSAAPTMIKMEVNGHG-----KAMALGEGPPLPAGVQVPAGPQ 1091 + I S T + + + H K G+G A + + G Sbjct: 187 ---------KECGRGFIHS---TDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTH 234 Query: 1092 TVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFT 1151 T P + C+ CGK F+ + L H +THTGEKP+ C CGRAFT Sbjct: 235 TGDNP----------------YECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFT 278 Query: 1152 TKGNLKVHMGTHM 1164 L HM H+ Sbjct: 279 VSSCLSQHMKIHV 291 Score = 62.4 bits (150), Expect = 3e-09 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 4/84 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C+ C + + + +H R HTGE+P+KCK CG++F+ + + H H + P Sbjct: 463 PFTCMECGKAFKFPTCVNLHMRIHTGEKPYKCKQCGKSFSYSNSFQLHERTHTGEKP--- 519 Query: 738 QHSCPICQKKFTNAVVLQQHIRMH 761 + C C K F+++ + H R H Sbjct: 520 -YECKECGKAFSSSSSFRNHERRH 542 Score = 60.1 bits (144), Expect = 1e-08 Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P +C+ C + + S+L H RTH+ ++PF C CG+AF + H +H + P Sbjct: 435 PFECLECGKAFTHSSSLNNHMRTHSAKKPFTCMECGKAFKFPTCVNLHMRIHTGEKP--- 491 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 + C C K F+ + Q H R H G Sbjct: 492 -YKCKQCGKSFSYSNSFQLHERTHTG 516 Score = 58.5 bits (140), Expect = 4e-08 Identities = 21/54 (38%), Positives = 36/54 (66%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEK 473 +KC+ C K F ++ Q+H R+HTGE+P++C CG FS+ + + H +RH ++ Sbjct: 492 YKCKQCGKSFSYSNSFQLHERTHTGEKPYECKECGKAFSSSSSFRNHERRHADE 545 Score = 57.4 bits (137), Expect = 9e-08 Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 4/80 (5%) Query: 684 CHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPI 743 C R + L + +TH E+P+KCK CG+ F L H G H P + C Sbjct: 189 CGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDNP----YECKE 244 Query: 744 CQKKFTNAVVLQQHIRMHMG 763 C K FT + L QH + H G Sbjct: 245 CGKAFTRSCQLTQHRKTHTG 264 Score = 57.4 bits (137), Expect = 9e-08 Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 +A+DPF +C+ C K F + S L H R HTG +P+KC CG F+ +L H + H Sbjct: 319 TAKDPF---ECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGKAFTQNSDLTKHARTHS 375 Query: 472 EKYPH 476 + P+ Sbjct: 376 GERPY 380 Score = 56.6 bits (135), Expect = 2e-07 Identities = 26/64 (40%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 S E P+ +C+ C K F S L H R+HTGE+PF+C CG F+ NL H + H Sbjct: 375 SGERPY---ECKECGKAFARSSRLSEHTRTHTGEKPFECVKCGKAFAISSNLSGHLRIHT 431 Query: 472 EKYP 475 + P Sbjct: 432 GEKP 435 Score = 55.8 bits (133), Expect = 3e-07 Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 SA+ PF C C K F + + +H+R HTGE+P+KC CG FS + ++H + H Sbjct: 459 SAKKPF---TCMECGKAFKFPTCVNLHMRIHTGEKPYKCKQCGKSFSYSNSFQLHERTHT 515 Query: 472 EKYPH 476 + P+ Sbjct: 516 GEKPY 520 Score = 55.5 bits (132), Expect = 3e-07 Identities = 27/64 (42%), Positives = 34/64 (53%), Gaps = 3/64 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + E PF +C C K F S L HLR HTGE+PF+C CG F+ +L H + H Sbjct: 403 TGEKPF---ECVKCGKAFAISSNLSGHLRIHTGEKPFECLECGKAFTHSSSLNNHMRTHS 459 Query: 472 EKYP 475 K P Sbjct: 460 AKKP 463 Score = 54.7 bits (130), Expect = 6e-07 Identities = 22/56 (39%), Positives = 32/56 (57%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475 +KC+ C K F +S L H R+H+GERP++C CG F+ L H + H + P Sbjct: 352 YKCKDCGKAFTQNSDLTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTGEKP 407 Score = 52.8 bits (125), Expect = 2e-06 Identities = 21/55 (38%), Positives = 31/55 (56%) Query: 1113 HNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNN 1167 H + CG+ F ++ L + +TH EKP+ C CG+ F L +HMGTH +N Sbjct: 184 HEWKECGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDN 238 Score = 51.6 bits (122), Expect = 5e-06 Identities = 20/56 (35%), Positives = 30/56 (53%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYP 475 +KC+ C + F S L H++ H GE+P++C CG F+ L H + H K P Sbjct: 268 YKCKDCGRAFTVSSCLSQHMKIHVGEKPYECKECGIAFTRSSQLTEHLKTHTAKDP 323 Score = 50.8 bits (120), Expect = 8e-06 Identities = 20/57 (35%), Positives = 31/57 (54%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C K F L H ++HTGE+P+KC CG F+ L H + H + P+ Sbjct: 240 YECKECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQHMKIHVGEKPY 296 Score = 50.1 bits (118), Expect = 1e-05 Identities = 20/57 (35%), Positives = 32/57 (56%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 +KC+ C K F + L IH+ +HTG+ P++C CG F+ L H + H + P+ Sbjct: 212 YKCKECGKGFRYSAYLNIHMGTHTGDNPYECKECGKAFTRSCQLTQHRKTHTGEKPY 268 Score = 48.9 bits (115), Expect = 3e-05 Identities = 21/57 (36%), Positives = 30/57 (52%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 ++C+ C F S L HL++HT + PF+C ICG F L HF+ H P+ Sbjct: 296 YECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPY 352 Score = 46.6 bits (109), Expect = 2e-04 Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 412 SAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHK 471 + E PF +C C K F S+L H+R+H+ ++PF C CG F + +H + H Sbjct: 431 TGEKPF---ECLECGKAFTHSSSLNNHMRTHSAKKPFTCMECGKAFKFPTCVNLHMRIHT 487 Query: 472 EKYPH 476 + P+ Sbjct: 488 GEKPY 492 Score = 41.6 bits (96), Expect = 0.005 Identities = 16/57 (28%), Positives = 28/57 (49%) Query: 420 HKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 H+ + C + F + L + +++H E+P+KC CG F L +H H P+ Sbjct: 184 HEWKECGRGFIHSTDLAVRIQTHRSEKPYKCKECGKGFRYSAYLNIHMGTHTGDNPY 240 Score = 38.1 bits (87), Expect = 0.055 Identities = 20/55 (36%), Positives = 27/55 (49%) Query: 422 CRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPH 476 C K F + S LQ HLR+H GE + CG F +L V Q H+ + P+ Sbjct: 158 CSDSGKSFINHSHLQGHLRTHNGESLHEWKECGRGFIHSTDLAVRIQTHRSEKPY 212 Score = 36.6 bits (83), Expect = 0.16 Identities = 37/129 (28%), Positives = 52/129 (40%), Gaps = 23/129 (17%) Query: 654 DSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICG 713 D + +S +Q + + +++D QC V S S LK H RT E F+C + G Sbjct: 56 DVLGEPTSSGIQMIGSHNGGEVSDVKQC---GDVSSEHSCLKTHVRTQNSENTFECYLYG 112 Query: 714 RAFTTKGNLKTHFGVHRA-----------KPPLRVQHSCP-----ICQ---KKFTNAVVL 754 F T + KT G R+ P + Q +C C K F N L Sbjct: 113 VDFLTL-HKKTSTGEQRSVFSQCGKAFSLNPDVVCQRTCTGEKAFDCSDSGKSFINHSHL 171 Query: 755 QQHIRMHMG 763 Q H+R H G Sbjct: 172 QGHLRTHNG 180 >gi|13376064 zinc finger protein 408 [Homo sapiens] Length = 720 Score = 90.1 bits (222), Expect = 1e-17 Identities = 92/315 (29%), Positives = 129/315 (40%), Gaps = 63/315 (20%) Query: 873 DRLSNDSSSAV-----GDLESR---SAGSPALSESSSSQALSPAPSNGESFRSKSPG--- 921 DR+S DS GD++ A P +S+S+ P S G SF S + G Sbjct: 243 DRISKDSQPLGPLLQDGDVDEECPAQAQMPPELQSNSATQQDPDGS-GASFSSSARGTQP 301 Query: 922 -------LGAPEEPQEIPLKTERPDSPAAAPG----SGGAPGRAGIKEEAPFSLLFLSRE 970 L +P + + P + + P+ A G S PG AG S + Sbjct: 302 HGYLAKKLHSPSD--QCPPRAKTPEPGAQQSGFPTLSRSPPGPAGS-----------SPK 348 Query: 971 RGKCPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-L 1029 +G+ CG CGK F L+ H HT +PF+C C + S+ + K H+L HR + Sbjct: 349 QGR--RYRCGECGKAFLQLCHLKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGV 406 Query: 1030 KELPSQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGV-QVPA 1088 + P D + ++ S A + GKA A L QVPA Sbjct: 407 RPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQC---GKAFARRPSLRLHRKTHQVPA 463 Query: 1089 GPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGR 1148 P AP P C CG+ ++ +L+ H R HTGEKPF C CGR Sbjct: 464 AP------------APCP--------CPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGR 503 Query: 1149 AFTTKGNLKVHMGTH 1163 AF +GNL+ H+ H Sbjct: 504 AFRQRGNLRGHLRLH 518 Score = 83.6 bits (205), Expect = 1e-15 Identities = 89/333 (26%), Positives = 127/333 (38%), Gaps = 57/333 (17%) Query: 885 DLESRSA------GSPALSESSSSQALSP---------APSNGESFRSKSPGLGAPEEPQ 929 +L+S SA GS A S SSS++ P +PS+ R+K+P GA + Sbjct: 274 ELQSNSATQQDPDGSGA-SFSSSARGTQPHGYLAKKLHSPSDQCPPRAKTPEPGAQQSG- 331 Query: 930 EIPLKTERPDSPAAAPGSGGAPGRAGIKEEAPFSLLFLSRER----GKCPSTVCGVCGKP 985 P + P PA + G R G +A L L + G P +C CGK Sbjct: 332 -FPTLSRSPPGPAGSSPKQGRRYRCGECGKAFLQLCHLKKHAFVHTGHKPF-LCTECGKS 389 Query: 986 FACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHR-LKELPSQLFDPNFALG 1044 ++ + + + H H RPF C C + T +LK+H + H + FA Sbjct: 390 YSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARR 449 Query: 1045 PSQSTPSLISS--AAPTMIKMEVNGHGKA----------MALGEGP-------------- 1078 PS AAP V G A + GE P Sbjct: 450 PSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRG 509 Query: 1079 PLPAGVQVPAGPQTVMGPGLAPMLAPPPR-------RTPKQHNCQSCGKTFSSASALQIH 1131 L +++ G + P A P T + H C CGK L+ H Sbjct: 510 NLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAH 569 Query: 1132 ERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHM 1164 ER H+GE+PF C CGRA+T L+ H+ +H+ Sbjct: 570 ERLHSGERPFPCPQCGRAYTLATKLRRHLKSHL 602 Score = 76.6 bits (187), Expect = 1e-13 Identities = 36/86 (41%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C +C R L+ Q +L+ H R HTGE+PF C CGRAF +GNL+ H +H + P R Sbjct: 467 PCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYR- 525 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 CP C F L++H+ H G Sbjct: 526 ---CPHCADAFPQLPELRRHLISHTG 548 Score = 72.0 bits (175), Expect = 3e-12 Identities = 56/190 (29%), Positives = 83/190 (43%), Gaps = 28/190 (14%) Query: 974 CPSTVCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLKELP 1033 CP C VCG+P A + +L H R HT E+PF+C C R GNL+ HL H E P Sbjct: 468 CP---CPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHT-GERP 523 Query: 1034 SQLFDPNFALGPSQSTPSLISSAAPTMIKMEVNGHGKAMALGEGPPLPAGVQVPAGPQTV 1093 + P+ A + P L ++ + H GE P + P T+ Sbjct: 524 YRC--PHCA----DAFPQLPE------LRRHLISH-----TGEAHLCPVCGKALRDPHTL 566 Query: 1094 MGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTK 1153 L R P C CG+ ++ A+ L+ H ++H +KP+ C CG +T Sbjct: 567 RAH---ERLHSGERPFP----CPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLP 619 Query: 1154 GNLKVHMGTH 1163 +L+ H +H Sbjct: 620 QSLRRHQLSH 629 Score = 64.3 bits (155), Expect = 7e-10 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 1/86 (1%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + Q LK H H+G RPF C CG+AF + +L+ H H+ P Sbjct: 408 PFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARRPSLRLHRKTHQV-PAAPA 466 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 CP+C + N L+ H+R+H G Sbjct: 467 PCPCPVCGRPLANQGSLRNHMRLHTG 492 Score = 63.5 bits (153), Expect = 1e-09 Identities = 35/108 (32%), Positives = 49/108 (45%), Gaps = 8/108 (7%) Query: 663 KLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNL 722 +L +L ++ + + C +C + L L+ H R H+GERPF C CGRA+T L Sbjct: 535 QLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTLATKL 594 Query: 723 KTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTP 770 + H H P R CP C +T L Q +R H P P Sbjct: 595 RRHLKSHLEDKPYR----CPTCGMGYT----LPQSLRRHQLSHRPEAP 634 Score = 59.7 bits (143), Expect = 2e-08 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 5/86 (5%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C R + L+ H R HTGERP++C C AF L+ H H + Sbjct: 495 PFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGE----- 549 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMG 763 H CP+C K + L+ H R+H G Sbjct: 550 AHLCPVCGKALRDPHTLRAHERLHSG 575 Score = 57.4 bits (137), Expect = 9e-08 Identities = 32/95 (33%), Positives = 43/95 (45%), Gaps = 7/95 (7%) Query: 678 PNQCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRV 737 P C C + S + + K H H G RPF C C +A+ T+ +LK H VH P Sbjct: 380 PFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARPF-- 437 Query: 738 QHSCPICQKKFTNAVVLQQHIRMHMGGQIPNTPLP 772 +C C K F L+ H + H Q+P P P Sbjct: 438 --ACDQCGKAFARRPSLRLHRKTH---QVPAAPAP 467 Score = 56.6 bits (135), Expect = 2e-07 Identities = 72/303 (23%), Positives = 99/303 (32%), Gaps = 60/303 (19%) Query: 288 GAQPLSRPESGASTPGGPA------EPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSAS 341 GA+P + + G + P+ PAAP+ P P P S + Sbjct: 433 GARPFACDQCGKAFARRPSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLHTG 492 Query: 342 TPPALAP--GSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKG 399 P L P G L L T P+ A+A L L +H Sbjct: 493 EKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPH-------CADAFPQLPELRRHLIS 545 Query: 400 KPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFST 459 H C C K L+ H R H+GERPF C CG ++ Sbjct: 546 HTGEA---------------HLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTL 590 Query: 460 KGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKPVL 519 L+ H + H E P+ PTC G+ Y + P+ L +P Sbjct: 591 ATKLRRHLKSHLEDKPY-------------RCPTC-GMGYTL---PQSLRRHQLSHRPEA 633 Query: 520 PTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSA 579 P PP+VP A A P+ PQ E +SP + VE +S Sbjct: 634 PC--------SPPSVPSA---ASEPTVVLLQAEPQLLDTHREE--EVSPARDVVEVTISE 680 Query: 580 TAE 582 + E Sbjct: 681 SQE 683 Score = 52.4 bits (124), Expect = 3e-06 Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 4/86 (4%) Query: 680 QCVICHRVLSCQSALKMHYRTHTGERPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQH 739 +C C + LK H HTG +PF C CG++++++ + K H HR P Sbjct: 354 RCGECGKAFLQLCHLKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGVRPF---- 409 Query: 740 SCPICQKKFTNAVVLQQHIRMHMGGQ 765 CP C K + L++H +H G + Sbjct: 410 PCPQCDKAYGTQRDLKEHQVVHSGAR 435 Score = 52.4 bits (124), Expect = 3e-06 Identities = 21/56 (37%), Positives = 32/56 (57%) Query: 1115 CQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHMGTHMWNNAPA 1170 C C K + + L+ H+ H+G +PF C CG+AF + +L++H TH APA Sbjct: 411 CPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARRPSLRLHRKTHQVPAAPA 466 Score = 50.4 bits (119), Expect = 1e-05 Identities = 67/287 (23%), Positives = 99/287 (34%), Gaps = 33/287 (11%) Query: 222 LIEQIRSQVALMQRPPPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPA 281 ++ ++ S V P + P P + P+ Q + + L S P Sbjct: 193 VVTEVESAVQQEVASPGEDAAEPCIDPGSQSPSGIQAENMVSPGLKFPTQDRISKDSQPL 252 Query: 282 APAAFEG-------AQPLSRPE--SGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSA 332 P +G AQ PE S ++T P A + SA A S Sbjct: 253 GPLLQDGDVDEECPAQAQMPPELQSNSATQQDPDGSGASFSSSARGTQPHGYLAKKLHSP 312 Query: 333 ASSQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNPLVSIAATANALDPLSA 392 + P A TP PG+ P L P A A L Sbjct: 313 SDQCPPRAKTPE---PGAQQSGFPTLSRS--PPGPAGSSPKQGRRYRCGECGKAFLQLCH 367 Query: 393 LMKH---RKGKPPNVSVFEPKA-SAEDPFFKHK----------CRFCAKVFGSDSALQIH 438 L KH G P + K+ S+E+ F H C C K +G+ L+ H Sbjct: 368 LKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEH 427 Query: 439 LRSHTGERPFKCNICGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVP 485 H+G RPF C+ CG F+ + +L++H + H+ + P P P Sbjct: 428 QVVHSGARPFACDQCGKAFARRPSLRLHRKTHQ-----VPAAPAPCP 469 Score = 45.1 bits (105), Expect = 5e-04 Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 8/83 (9%) Query: 979 CGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRLK------EL 1032 C CG+ + + L H +SH +++P+ C C G + +L++H L+HR + + Sbjct: 581 CPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHRPEAPCSPPSV 640 Query: 1033 PSQLFDPNFALGPSQSTPSLISS 1055 PS +P L Q+ P L+ + Sbjct: 641 PSAASEPTVVL--LQAEPQLLDT 661 Score = 34.3 bits (77), Expect = 0.80 Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 4/59 (6%) Query: 705 RPFKCKICGRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMHMG 763 R ++C CG+AF +LK H VH P C C K +++ + H+ H G Sbjct: 351 RRYRCGECGKAFLQLCHLKKHAFVHTGHKPF----LCTECGKSYSSEESFKAHMLGHRG 405 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.129 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 65,848,018 Number of Sequences: 37866 Number of extensions: 4272017 Number of successful extensions: 134631 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1868 Number of HSP's successfully gapped in prelim test: 2544 Number of HSP's that attempted gapping in prelim test: 27173 Number of HSP's gapped (non-prelim): 75669 length of query: 1300 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1186 effective length of database: 13,930,794 effective search space: 16521921684 effective search space used: 16521921684 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.