Search of human proteins with 154146191

Search of human proteins with 154146191

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
sapiens]
         (732 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s...  1451   0.0  
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s...  1451   0.0  
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]          1263   0.0  
gi|4507677 heat shock protein 90kDa beta, member 1 [Homo sapiens]     639   0.0  
gi|155722983 TNF receptor-associated protein 1 [Homo sapiens]         196   5e-50
gi|221219020 NYD-SP11 protein [Homo sapiens]                           65   3e-10
gi|55741661 hypothetical protein LOC57653 [Homo sapiens]               59   2e-08
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    57   8e-08
gi|34878777 ring finger protein 20 [Homo sapiens]                      56   1e-07
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            55   2e-07
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          55   2e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens]               52   2e-06
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    52   3e-06
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     51   3e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            50   1e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    50   1e-05
gi|4757900 calreticulin precursor [Homo sapiens]                       49   2e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        49   2e-05
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     48   3e-05
gi|4758220 XAP-5 protein [Homo sapiens]                                48   4e-05
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    47   5e-05
gi|215422388 death-domain associated protein isoform a [Homo sap...    47   5e-05
gi|215422366 death-domain associated protein isoform b [Homo sap...    47   5e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     47   5e-05
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              47   5e-05
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is...    47   6e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    47   6e-05
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    47   6e-05
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    47   6e-05
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ...    47   6e-05

>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
           sapiens]
          Length = 732

 Score = 1451 bits (3756), Expect = 0.0
 Identities = 732/732 (100%), Positives = 732/732 (100%)

Query: 1   MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 60
           MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR
Sbjct: 1   MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 60

Query: 61  YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
           YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME
Sbjct: 61  YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120

Query: 121 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 180
           ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM
Sbjct: 121 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 180

Query: 181 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED 240
           GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED
Sbjct: 181 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED 240

Query: 241 KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN 300
           KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN
Sbjct: 241 KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN 300

Query: 301 PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN 360
           PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN
Sbjct: 301 PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN 360

Query: 361 IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 420
           IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC
Sbjct: 361 IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 420

Query: 421 LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY 480
           LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY
Sbjct: 421 LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY 480

Query: 481 CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT 540
           CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT
Sbjct: 481 CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT 540

Query: 541 LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV 600
           LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV
Sbjct: 541 LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV 600

Query: 601 TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK 660
           TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK
Sbjct: 601 TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK 660

Query: 661 DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE 720
           DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE
Sbjct: 661 DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE 720

Query: 721 GDDDTSRMEEVD 732
           GDDDTSRMEEVD
Sbjct: 721 GDDDTSRMEEVD 732


>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
           sapiens]
          Length = 854

 Score = 1451 bits (3756), Expect = 0.0
 Identities = 732/732 (100%), Positives = 732/732 (100%)

Query: 1   MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 60
           MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR
Sbjct: 123 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 182

Query: 61  YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
           YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME
Sbjct: 183 YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 242

Query: 121 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 180
           ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM
Sbjct: 243 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 302

Query: 181 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED 240
           GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED
Sbjct: 303 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED 362

Query: 241 KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN 300
           KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN
Sbjct: 363 KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN 422

Query: 301 PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN 360
           PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN
Sbjct: 423 PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN 482

Query: 361 IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 420
           IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC
Sbjct: 483 IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 542

Query: 421 LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY 480
           LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY
Sbjct: 543 LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY 602

Query: 481 CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT 540
           CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT
Sbjct: 603 CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT 662

Query: 541 LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV 600
           LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV
Sbjct: 663 LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV 722

Query: 601 TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK 660
           TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK
Sbjct: 723 TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK 782

Query: 661 DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE 720
           DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE
Sbjct: 783 DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE 842

Query: 721 GDDDTSRMEEVD 732
           GDDDTSRMEEVD
Sbjct: 843 GDDDTSRMEEVD 854


>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
          Length = 724

 Score = 1263 bits (3268), Expect = 0.0
 Identities = 628/732 (85%), Positives = 684/732 (93%), Gaps = 8/732 (1%)

Query: 1   MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 60
           MPEE         EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIR
Sbjct: 1   MPEEVHHG-----EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIR 55

Query: 61  YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
           YESLTDPSKLDSGKEL I++IPN Q+RTLT+VDTGIGMTKADLINNLGTIAKSGTKAFME
Sbjct: 56  YESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFME 115

Query: 121 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 180
           ALQAGADISMIGQFGVGFYSAYLVAEKV VITKHNDDEQYAWESSAGGSFTVR D GEP+
Sbjct: 116 ALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPI 175

Query: 181 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED 240
           GRGTKVILHLKEDQTEYLEERR+KE+VKKHSQFIGYPITL++EKER+KE+SDDEAEE++ 
Sbjct: 176 GRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKG 235

Query: 241 KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN 300
              EKE+E+K+ E+KP+IEDVGSDEE++     KKK KKIKEKYIDQEELNKTKPIWTRN
Sbjct: 236 ---EKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRN 292

Query: 301 PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN 360
           PDDIT EEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF+PRRAPFDLFEN+KKKNN
Sbjct: 293 PDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNN 352

Query: 361 IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 420
           IKLYVRRVFIMD+C+ELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKN+VKKC
Sbjct: 353 IKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKC 412

Query: 421 LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY 480
           LELF+ELAEDKENYKKFYE FSKN+KLGIHEDS NR++LSELLRY+TS SGDEM SL +Y
Sbjct: 413 LELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEY 472

Query: 481 CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT 540
            +RMKE QK IYYITGE+K+QVANSAFVER+RK G EV+YM EPIDEYCVQQLKEF+GK+
Sbjct: 473 VSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKS 532

Query: 541 LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV 600
           LVSVTKEGLELPEDEEEKKK EE K KFENLCK+MK+IL+KKVEKV +SNRLV+SPCCIV
Sbjct: 533 LVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIV 592

Query: 601 TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK 660
           TSTYGWTANMERIMKAQALRDNSTMGYM AKKHLEINPDH I+ETLRQKAEADKNDK+VK
Sbjct: 593 TSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVK 652

Query: 661 DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE 720
           DLV+LL+ETALLSSGFSLEDPQTH+NRIYRMIKLGLGIDED+  A++ +AAV +E+PPLE
Sbjct: 653 DLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLE 712

Query: 721 GDDDTSRMEEVD 732
           GD+D SRMEEVD
Sbjct: 713 GDEDASRMEEVD 724


>gi|4507677 heat shock protein 90kDa beta, member 1 [Homo sapiens]
          Length = 803

 Score =  639 bits (1648), Expect = 0.0
 Identities = 345/729 (47%), Positives = 479/729 (65%), Gaps = 27/729 (3%)

Query: 15  EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 74
           E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR  SLTD + L   +
Sbjct: 71  EKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNE 130

Query: 75  ELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAGADIS- 129
           EL + +  +K+   L + DTG+GMT+ +L+ NLGTIAKSGT  F+    EA + G   S 
Sbjct: 131 ELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSE 190

Query: 130 MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILH 189
           +IGQFGVGFYSA+LVA+KV V +KHN+D Q+ WES +     +    G  +GRGT + L 
Sbjct: 191 LIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLV 250

Query: 190 LKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEE 249
           LKE+ ++YLE   IK +VKK+SQFI +PI ++  K         E  E+  +EEE  KEE
Sbjct: 251 LKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKT--------ETVEEPMEEEEAAKEE 302

Query: 250 KESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEY 309
           KE  D    ++   +EEEE+K   K K KK+++   D E +N  KPIW R   ++  +EY
Sbjct: 303 KEESD----DEAAVEEEEEEK---KPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEY 355

Query: 310 GEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFEN--RKKKNNIKLYVRR 367
             FYKS + + +D +A  HF+ EG++ F+++LFVP  AP  LF+    KK + IKLYVRR
Sbjct: 356 KAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRR 415

Query: 368 VFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTEL 427
           VFI D+  +++P+YLNF++GVVDS+DLPLN+SRE LQQ K+LKVIRK LV+K L++  ++
Sbjct: 416 VFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKI 475

Query: 428 AEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKEN 487
           A+DK N   F+++F  NIKLG+ ED  NR +L++LLR+ +S    ++ SL  Y  RMKE 
Sbjct: 476 ADDKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEK 534

Query: 488 QKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKE 547
           Q  IY++ G ++ +  +S FVERL K G EVIY+ EP+DEYC+Q L EF+GK   +V KE
Sbjct: 535 QDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKE 594

Query: 548 GLELPEDEEEKKKQEEKKTKFENLCKIMKD-ILEKKVEKVVVSNRLVTSPCCIVTSTYGW 606
           G++  E E+ K+ +E  + +FE L   MKD  L+ K+EK VVS RL  SPC +V S YGW
Sbjct: 595 GVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGW 654

Query: 607 TANMERIMKAQAL---RDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLV 663
           + NMERIMKAQA    +D ST  Y + KK  EINP H +I  + ++ + D++DK+V DL 
Sbjct: 655 SGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLA 714

Query: 664 ILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDD 723
           ++L+ETA L SG+ L D + + +RI RM++L L ID D    ++      E       D 
Sbjct: 715 VVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDT 774

Query: 724 DTSRMEEVD 732
           +    EE+D
Sbjct: 775 EQDEDEEMD 783



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 2/73 (2%)

Query: 208 KKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEE 267
           K +   I   + L +  + D +V ++  EE E+  E+  ++ ++ ED  E  DVG+DEEE
Sbjct: 733 KAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDED--EEMDVGTDEEE 790

Query: 268 EKKDGDKKKKKKI 280
           E       +K ++
Sbjct: 791 ETAKESTAEKDEL 803



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 17/54 (31%), Positives = 30/54 (55%)

Query: 237 EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEEL 290
           + + K EE+ +EE E   +   ED   DE+EE   G  ++++  KE   +++EL
Sbjct: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803


>gi|155722983 TNF receptor-associated protein 1 [Homo sapiens]
          Length = 704

 Score =  196 bits (499), Expect = 5e-50
 Identities = 120/421 (28%), Positives = 225/421 (53%), Gaps = 21/421 (4%)

Query: 284 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 343
           Y++   +N  + IW  +P D+   ++ EFY+ +    +      H+  +  L  R++ +V
Sbjct: 286 YLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYV 345

Query: 344 PRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREML 403
           P   P     +R+  +++ LY R+V I     +++P++L FIRGVVDSED+PLN+SRE+L
Sbjct: 346 PDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELL 405

Query: 404 QQSKILKVIRKNLVKKCLELFTELA-EDKENYKKFYEQFSKNIKLGI--HEDSQNRKKLS 460
           Q+S +++ +R  L ++ ++ F + + +D E Y KF+E +   ++ GI    + + ++ ++
Sbjct: 406 QESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIA 465

Query: 461 ELLRYYTSA-SGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVI 519
           +LLRY +SA    ++ SL +Y +RM+   ++IYY+    +    +S + E ++K   EV+
Sbjct: 466 KLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVL 525

Query: 520 YMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQ--------EEKKTKFENL 571
           +  E  DE  +  L+EF+ K L+SV  + + +   +EEK +          EK+T  E L
Sbjct: 526 FCFEQFDELTLLHLREFDKKKLISVETD-IVVDHYKEEKFEDRSPAAECLSEKET--EEL 582

Query: 572 CKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAK 631
              M+++L  +V  V V+ RL T P  +     G        ++ Q L           +
Sbjct: 583 MAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQ 639

Query: 632 KHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRM 691
             LEINP H++I+ L Q   ++     +  LV  +YE A++++G  ++DP+    R+  +
Sbjct: 640 PTLEINPRHALIKKLNQLRASEPGLAQL--LVDQIYENAMIAAGL-VDDPRAMVGRLNEL 696

Query: 692 I 692
           +
Sbjct: 697 L 697



 Score =  180 bits (456), Expect = 5e-45
 Identities = 100/241 (41%), Positives = 156/241 (64%), Gaps = 11/241 (4%)

Query: 22  FQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLI 81
           FQAE  +L+ ++  + YS KE+F+RELISN+SDAL+K+R++ ++D   L    E+ I+L 
Sbjct: 90  FQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALP---EMEIHLQ 146

Query: 82  PNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS--MIGQFGVGFY 139
            N +  T+TI DTGIGMT+ +L++NLGTIA+SG+KAF++ALQ  A+ S  +IGQFGVGFY
Sbjct: 147 TNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFY 206

Query: 140 SAYLVAEKVTVITKHNDDEQ--YAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEY 197
           SA++VA++V V ++        Y W S   G F +   +G  +  GTK+I+HLK D  E+
Sbjct: 207 SAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASG--VRTGTKIIIHLKSDCKEF 264

Query: 198 LEERRIKEIVKKHSQFIGYPITLFVEKERDKEV--SDDEAEEKEDKEEEKEKEEKESEDK 255
             E R++++V K+S F+ +P+ L   +    +     D  + +E + EE  +   ++ DK
Sbjct: 265 SSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDK 324

Query: 256 P 256
           P
Sbjct: 325 P 325


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 41/139 (29%), Positives = 84/139 (60%), Gaps = 12/139 (8%)

Query: 219  TLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKK 278
            +L  E E+ + +S +E EE+E++EE +E+E +E E++ + E+ G +++ EK++ +KKKKK
Sbjct: 2232 SLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKK 2291

Query: 279  KIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFR 338
            K K+K    EE+ + + ++    + ++ EE     +SL+++ E+    +  S+E +++ R
Sbjct: 2292 KEKKK----EEVQEKEEVFEEKEEIMSEEE----TESLSDEEEEE---ESCSLEEEVD-R 2339

Query: 339  ALLFVPRRAPFDLFENRKK 357
                + +   F L E R+K
Sbjct: 2340 EKEILKKEKQFKLQEQRRK 2358



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 21/87 (24%), Positives = 50/87 (57%)

Query: 222  VEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 281
            V++   +E   +E E   D+ E++E    E E++ E E+   +EE  +++ ++K++++ +
Sbjct: 2217 VDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276

Query: 282  EKYIDQEELNKTKPIWTRNPDDITNEE 308
            EK +++EE  K K    +  +++  +E
Sbjct: 2277 EKQVEKEEEEKKKKKKEKKKEEVQEKE 2303



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/114 (26%), Positives = 60/114 (52%), Gaps = 21/114 (18%)

Query: 191  KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 250
            +E++ E  EER  +E+ ++  +          E+  +K+V  +E E+K+ K+E+K++E +
Sbjct: 2247 EEEEREEEEEREEEEVREEEEE------RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQ 2300

Query: 251  ESED----------KPEIEDVGSDEEEE-----KKDGDKKKKKKIKEKYIDQEE 289
            E E+          + E E +  +EEEE     +++ D++K+   KEK    +E
Sbjct: 2301 EKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQE 2354



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 18/68 (26%), Positives = 38/68 (55%), Gaps = 2/68 (2%)

Query: 224  KERDKEVSDDEAE--EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 281
            K ++++  D+E    E+E   E +EKE++ +E++  I++        +K    +KK+  +
Sbjct: 1532 KSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQE 1591

Query: 282  EKYIDQEE 289
            E+ + QEE
Sbjct: 1592 ERKLAQEE 1599



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 223  EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
            ++E+  E     A+E+E   +EKEK  +  E  PE E+    + E+  +   K  +K +E
Sbjct: 1759 QREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQK-RE 1817

Query: 283  KYIDQ-EELNKTKPI 296
            ++I+  EEL K K I
Sbjct: 1818 RWINSMEELTKNKMI 1832



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 7/87 (8%)

Query: 238  KEDK--EEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKP 295
            KE+K  EEE +   K SE   + E+ G  EEEE     K++ +K KE     +  +K K 
Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKE----AKRGDKPKE 2211

Query: 296  IWTRNPDDITNEE-YGEFYKSLTNDWE 321
             ++   D++ +EE + E  +SL ++ E
Sbjct: 2212 KFSSQVDEVESEEHFSEEMESLLDELE 2238



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 18/66 (27%), Positives = 40/66 (60%), Gaps = 2/66 (3%)

Query: 226  RDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEI--EDVGSDEEEEKKDGDKKKKKKIKEK 283
            +++E++ +E +  E+K++  E+EE  +  + ++  E+    +EEE    +K+K  + KEK
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790

Query: 284  YIDQEE 289
              ++EE
Sbjct: 1791 MPEEEE 1796


>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
          Length = 1646

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 65/263 (24%), Positives = 125/263 (47%), Gaps = 27/263 (10%)

Query: 176  TGEPMGRGTKVILHLKEDQTEY-----LEERRIKEIVKKHSQFIGYPITLFVEKERDKEV 230
            T E +G+  K  LH K D+++      LEE +++     +       +    EK+ + E 
Sbjct: 849  TEEVLGQQKKSPLHAKMDESKEGSIQGLEEMQVEREGSLNPSLNEENVKGQGEKKEESEE 908

Query: 231  SDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEE- 289
             D++ EE+E+++ E+EKEEKE++++ E   VG  EEE+K++G       ++E Y +  E 
Sbjct: 909  EDEKEEEEEEEKLEEEKEEKEAQEEQESLSVG--EEEDKEEG-------LEEIYYEDMES 959

Query: 290  ----LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQ--LEFRALLFV 343
                   T  ++    ++   + +  F     ND      ++  ++  +  LE +  LF 
Sbjct: 960  FTISSGNTYFVFVPLEEEHCRKSHSTFSAMFINDTSSAKFIEQVTIPSRLILEIKKQLFS 1019

Query: 344  P--RRAPFDLFE--NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDS-EDLPLNI 398
                 +P ++    +R +K   ++ +    IM N E+L  EYL+    V++  E    N+
Sbjct: 1020 EGGNFSPKEINSLCSRLEKEAARIELVESVIMLNMEKLENEYLDQANDVINKFESKFHNL 1079

Query: 399  SREMLQQSKILKVIRKNLVK-KC 420
            S +++   KI +++    VK KC
Sbjct: 1080 SVDLIFIEKIQRLLTNLQVKIKC 1102


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 37/111 (33%), Positives = 62/111 (55%), Gaps = 17/111 (15%)

Query: 193 DQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEE-------- 244
           ++TE  EE   KE  +K  +           KE++K+    E E++++KEEE        
Sbjct: 14  EETEETEEEEEKEGKRKEKR-------KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66

Query: 245 -KEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTK 294
            K+KEE+E E++ E E+    EEEEK++G ++KKKK + +  ++EE  K +
Sbjct: 67  KKKKEEEEREEEEE-EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 28/74 (37%), Positives = 44/74 (59%), Gaps = 7/74 (9%)

Query: 223 EKERDKEVSDDEAEEKEDKE-------EEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKK 275
           +KE ++    +E EE+E+KE       +EK KE+++ +   E E     EEEEKK   K+
Sbjct: 7   KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66

Query: 276 KKKKIKEKYIDQEE 289
           KKKK +E+  ++EE
Sbjct: 67  KKKKEEEEREEEEE 80



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 26/93 (27%), Positives = 56/93 (60%), Gaps = 11/93 (11%)

Query: 191 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 250
           K+ +T+  E+R+ KE  +K  +           ++R K+  ++E EE+E++EEE+++EE+
Sbjct: 42  KKKKTKETEKRKEKEEEEKKRK-----------RKRKKKKEEEEREEEEEEEEEEKEEEE 90

Query: 251 ESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 283
           + E +   +      +EE+++  KK+++K K+K
Sbjct: 91  KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 24/74 (32%), Positives = 46/74 (62%), Gaps = 8/74 (10%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKE--------EKESEDKPEIEDVGSDEEEEKKDGDK 274
           +K++ K+   +E EE E+ EEE+EKE        EK  E + + +   +++ +EK++ +K
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 275 KKKKKIKEKYIDQE 288
           K+K+K K+K  ++E
Sbjct: 61  KRKRKRKKKKEEEE 74



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 7/69 (10%)

Query: 226 RDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYI 285
           + K+    E EE E+ EE +E+EEKE + K +        +E++K+ +KKKK K  EK  
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEK-------RKEKRKEKEKKKKTKETEKRK 53

Query: 286 DQEELNKTK 294
           ++EE  K +
Sbjct: 54  EKEEEEKKR 62


>gi|34878777 ring finger protein 20 [Homo sapiens]
          Length = 975

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 84/400 (21%), Positives = 171/400 (42%), Gaps = 66/400 (16%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEK-KDGDKKKKKKIK 281
           E+ER++   + E E + +KE+E+E+E+++ ++  +  D   D+E+ K  DG KK+ + IK
Sbjct: 568 ERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIK 627

Query: 282 EKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALL 341
           +  I+ ++  +++       D          Y+S   +  D + +     + + E   L 
Sbjct: 628 QLKIELKKAQESQKEMKLLLD---------MYRSAPKEQRDKVQLMAAEKKSKAELEDL- 677

Query: 342 FVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISRE 401
              R+   DL E+++KK N K+            E   EYL     +   E+        
Sbjct: 678 ---RQRLKDL-EDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEE------EA 727

Query: 402 MLQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGIHEDSQNRKKLS 460
           +L +  +     +++ ++ + L  +L E D  N+K   E+   N             ++ 
Sbjct: 728 LLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSN-------------QIH 774

Query: 461 ELLRYYTSASGDEMVSLKD------YCTRMKENQKHIYYI---TGETKDQVANSAFVERL 511
           +LL+       D++++LK          R  E ++H+      TGE K+    +  +E  
Sbjct: 775 KLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGE-KELGLRTQALEMN 833

Query: 512 RKHGLEVIYMIEPID---EYCVQQLKEFEGKTLV-SVTKEG-----LELPEDEEEKKKQE 562
           ++  +E   + + +    E   ++L +F+ + +  SVTKE          ED    +++ 
Sbjct: 834 KRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDMFNFKRAQEDISRLRRKL 893

Query: 563 EKKTKFENLCK----IMKDILEKKVEKVVVSNRLVTSPCC 598
           E   K +N+ K    +M++I + K          +T PCC
Sbjct: 894 ETTKKPDNVPKCDEILMEEIKDYKAR--------LTCPCC 925


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 30/63 (47%), Positives = 49/63 (77%), Gaps = 5/63 (7%)

Query: 227 DKEVSDDEAE-EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYI 285
           ++EV ++E E E+E+KEEEKE++E+E E + E E+   DEEEE+K+G K +++K++E+ I
Sbjct: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEE---DEEEEEKEGKKMEEEKVEEE-I 175

Query: 286 DQE 288
           D E
Sbjct: 176 DTE 178



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 22/64 (34%), Positives = 47/64 (73%), Gaps = 5/64 (7%)

Query: 236 EEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKK--KKIKEKYIDQE---EL 290
           EE+ ++EEE+ +EE++ E+K E E+    EEE+++D ++++K  KK++E+ +++E   E+
Sbjct: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEI 179

Query: 291 NKTK 294
            +T+
Sbjct: 180 QRTQ 183



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 20/58 (34%), Positives = 39/58 (67%), Gaps = 3/58 (5%)

Query: 235 AEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNK 292
           AEE   ++    +EE+  E++ E+E+   +E+EE+K+ D+++++K +EK  D+EE  K
Sbjct: 107 AEECSAQQGLPVEEEEVEEEEEEVEE---EEKEEEKEEDEEEEEKEEEKEEDEEEEEK 161



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 5/64 (7%)

Query: 524 PIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKV 583
           P++E  V++ +E      V   ++  E  EDEEE++K+EEK+   E   K  K + E+KV
Sbjct: 117 PVEEEEVEEEEEE-----VEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV 171

Query: 584 EKVV 587
           E+ +
Sbjct: 172 EEEI 175


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 30/99 (30%), Positives = 60/99 (60%), Gaps = 7/99 (7%)

Query: 224 KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 283
           ++ D+   +DE +E+ D+EEE+E EE++ +D  + EDV  +EEEE+++ +++++++ ++ 
Sbjct: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENED- 170

Query: 284 YIDQEELNKTKPIWTRNPDDITNEEYGEF----YKSLTN 318
              Q   + T+ +     DD  N+EY  +     KSL N
Sbjct: 171 --HQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLN 207



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 29/93 (31%), Positives = 51/93 (54%), Gaps = 7/93 (7%)

Query: 231 SDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEEL 290
           S DE ++ +  E+  EKEE E E+  E  D   DE+EE ++GD++++++I+E+  D +E 
Sbjct: 86  SVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDED 145

Query: 291 NKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDH 323
            +       + +D   EE  E  +    + EDH
Sbjct: 146 GE-------DVEDEEEEEEEEEEEEEEEENEDH 171


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 22/48 (45%), Positives = 38/48 (79%)

Query: 224 KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKD 271
           +E D+E  ++E EE+ED+EEE+E+EE+E E++ E E+   +EEEE+++
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 21/62 (33%), Positives = 45/62 (72%)

Query: 232 DDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELN 291
           +++ EE+E++EEE+E EE+E E++ E E+   +EEEE+++ +++++++     I QE+ +
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTS 318

Query: 292 KT 293
            T
Sbjct: 319 HT 320



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 20/49 (40%), Positives = 39/49 (79%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKD 271
           E+E ++E  ++E EE++++EEE+E+EE+E E++ E E+   +EEEE+++
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 19/60 (31%), Positives = 44/60 (73%)

Query: 224 KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 283
           +E  K+      EE++++EEE+E+EE+E E++ E E+   +EEEE+++ +++++++ +E+
Sbjct: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 32/138 (23%), Positives = 70/138 (50%), Gaps = 10/138 (7%)

Query: 168 GSFTVRTDTGEPMGRGTKV---ILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEK 224
           G     T   E +G+  K    I+HL ++  E       ++ +    +     + +  E+
Sbjct: 172 GQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTER 231

Query: 225 ERD--KEVSDDEAEEKEDKEE-----EKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKK 277
            +D   +  +D A E+  K++     E+E EE+E E++ E ED   +EEEE+++ +++++
Sbjct: 232 SQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291

Query: 278 KKIKEKYIDQEELNKTKP 295
           ++ +E+  ++EE  +  P
Sbjct: 292 EEEEEEEEEEEEEEEAAP 309



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 19/60 (31%), Positives = 39/60 (65%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
           E+E +++  ++E EE+E++EEE+E+EE+E E++ E E+  + +   ++D      +K  E
Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 20/90 (22%), Positives = 50/90 (55%), Gaps = 3/90 (3%)

Query: 222 VEKERDKEVSDDEAEEKEDKEEEKEK---EEKESEDKPEIEDVGSDEEEEKKDGDKKKKK 278
           V  ER +++     E+   +E  K+K     +E +++ E E+   +E+EE+++ ++++++
Sbjct: 227 VTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEE 286

Query: 279 KIKEKYIDQEELNKTKPIWTRNPDDITNEE 308
           + +E+  ++EE  + +      PD I  E+
Sbjct: 287 EEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
           theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 90/392 (22%), Positives = 161/392 (41%), Gaps = 69/392 (17%)

Query: 187 ILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS-DDEAEEKEDKEEEK 245
           IL  KE+Q +      +K   K+H + +    T+   KER + ++   E EE E +E E 
Sbjct: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAEL 601

Query: 246 EKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDIT 305
           +K  K  E++   E    ++E   ++ ++ KKK ++E+    E++ KT+ +  +   DI 
Sbjct: 602 QKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERL---EQIKKTE-LGAKAFKDID 657

Query: 306 NEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLY- 364
            E+  E       D +  +A +   +E + +        +    D FE  K+   I L  
Sbjct: 658 IEDLEEL------DPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIK 711

Query: 365 ----VRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 420
                +R+  MD  E+   E                 I+   L++ K L+   KN + + 
Sbjct: 712 SAYEEQRIKDMDLWEQQEEE----------------RITTMQLEREKALE--HKNRMSRM 753

Query: 421 LE---LFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSL 477
           LE   LF  +   K   +  YE+  K  +  + E+  NR                    L
Sbjct: 754 LEDRDLF--VMRLKAARQSVYEEKLKQFEERLAEERHNR--------------------L 791

Query: 478 KDYCTRMKENQKHIYYITGETKDQ--VANSAFVERLRKHGLEVIYMIEPIDEY--CVQQL 533
           ++   + KE ++  YY   E ++Q         ER  +   E     E + EY   V++L
Sbjct: 792 EERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKL 851

Query: 534 KEFEGKTLVSVTKEGLELPEDEEEKKKQEEKK 565
           +E E K      K   EL  +E E++++EE++
Sbjct: 852 EEVERK------KRQRELEIEERERRREEERR 877



 Score = 33.9 bits (76), Expect = 0.55
 Identities = 33/134 (24%), Positives = 59/134 (44%), Gaps = 26/134 (19%)

Query: 190 LKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERD----------KEVSDDEAEEKE 239
           LK+ +    EER  +   +K  +     IT + EKE +          KE  + E  E+ 
Sbjct: 776 LKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERA 835

Query: 240 DKEEE-----------KEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQE 288
            +EEE           +E E K+ + + EIE+     EEE++ GD    +K   ++ D++
Sbjct: 836 KREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRK-DSRWGDRD 894

Query: 289 ELNKTKPIWTRNPD 302
               ++  W + P+
Sbjct: 895 ----SEGTWRKGPE 904


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 32/100 (32%), Positives = 54/100 (54%), Gaps = 13/100 (13%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
           EKE ++   ++E ++KE+KEEE+E+E K+ E++ EI +  ++EE E KD +         
Sbjct: 375 EKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRN-KNEEEGESKDEE--------- 424

Query: 283 KYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWED 322
              D++E    KP      D  T E YGE  +   ++ +D
Sbjct: 425 ---DEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQD 461



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 28/90 (31%), Positives = 48/90 (53%), Gaps = 9/90 (10%)

Query: 227 DKEVSDDEAEEKEDKEEEKEKEEKESEDKPEI-----EDVGSDEEEEKKDGDKKKKKKIK 281
           ++E S+DE    ED+++E  +    S+D+ +      +++   EEEE K  ++ KKK+ K
Sbjct: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393

Query: 282 EKYIDQEELNKTKPIWTRNPDDITNEEYGE 311
           E+  ++E   K +    RN     NEE GE
Sbjct: 394 EEEEEEEMKQKEEEEEIRN----KNEEEGE 419


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 30/101 (29%), Positives = 53/101 (52%), Gaps = 1/101 (0%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKE-EKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 281
           E+ER +E   +E +E+E K+EE+EKE E++   K E + VG  EEE K+   K++KK+ +
Sbjct: 132 ERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER 191

Query: 282 EKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWED 322
            +   ++E  + +    +       E   E  K    +W +
Sbjct: 192 NRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWRE 232



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 25/78 (32%), Positives = 47/78 (60%), Gaps = 4/78 (5%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKE----SEDKPEIEDVGSDEEEEKKDGDKKKKK 278
           E+ER K   + E +E E+KE+ K+KE+KE    S++  E E     + EE+K+ ++KK++
Sbjct: 94  ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153

Query: 279 KIKEKYIDQEELNKTKPI 296
           + KE+   + +  + K +
Sbjct: 154 REKERERKERKKRERKQV 171



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 30/106 (28%), Positives = 60/106 (56%), Gaps = 2/106 (1%)

Query: 191 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 250
           KE ++E  +ERR +E  K+  +          EK+ +++  + E +++  ++E KE EEK
Sbjct: 53  KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112

Query: 251 ESEDKPEIEDVG--SDEEEEKKDGDKKKKKKIKEKYIDQEELNKTK 294
           E   K E ++ G  S E +E++  +++K+++ KE+   +EE  K +
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 31/104 (29%), Positives = 54/104 (51%), Gaps = 19/104 (18%)

Query: 191 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSD-----DEAEEKEDKEEEK 245
           K+++ E  + RR KE  +   +          EK + KE  +      E +E+E KEE K
Sbjct: 91  KKEERERKKRRREKENKEGEEK----------EKRKKKEKKERGRTSKEGKERERKEERK 140

Query: 246 EKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEE 289
            +E KE E K E      ++E E+K+  K+++K++ EK  +++E
Sbjct: 141 REERKERERKKE----EREKERERKERKKRERKQVGEKEEERKE 180



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 23/64 (35%), Positives = 39/64 (60%), Gaps = 3/64 (4%)

Query: 223 EKER---DKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKK 279
           +KER    KE  + E +E+  +EE KE+E K+ E + E E     + E K+ G+K++++K
Sbjct: 120 KKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERK 179

Query: 280 IKEK 283
            KE+
Sbjct: 180 EKER 183



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 25/104 (24%), Positives = 55/104 (52%), Gaps = 9/104 (8%)

Query: 191 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 250
           K+++ E  +ER  KE  K+  + +G       EKE +++  + +  +K ++  ++ K+E+
Sbjct: 150 KKEERE--KERERKERKKRERKQVG-------EKEEERKEKERKERKKRERNRKERKKER 200

Query: 251 ESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTK 294
           E +++ E +     +EE KK+  K ++   +EK   + E  + K
Sbjct: 201 ERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 20/73 (27%), Positives = 39/73 (53%)

Query: 222 VEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 281
           +E  ++ +   +   +KE +E EK K E+E E K E        E +K++ ++KK+++ K
Sbjct: 45  IETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREK 104

Query: 282 EKYIDQEELNKTK 294
           E    +E+  + K
Sbjct: 105 ENKEGEEKEKRKK 117



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 21/73 (28%), Positives = 44/73 (60%), Gaps = 1/73 (1%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEK-EKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 281
           ++ER+++    E E KE +E+EK +K+EK+   +   E    + +EE+K  ++K++++ K
Sbjct: 92  KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151

Query: 282 EKYIDQEELNKTK 294
           E+   + E  + K
Sbjct: 152 EEREKERERKERK 164



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 21/73 (28%), Positives = 41/73 (56%), Gaps = 1/73 (1%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
           E E  KE   +   E++ +  E+EK ++E E + + E    +++ E+K  ++++KK+ +E
Sbjct: 44  EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103

Query: 283 KYIDQ-EELNKTK 294
           K   + EE  K K
Sbjct: 104 KENKEGEEKEKRK 116



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 19/66 (28%), Positives = 37/66 (56%)

Query: 229 EVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQE 288
           E+ + E E +  KE +KE+E +  +++ E E    + E+E+K    KK+KK + K  ++E
Sbjct: 37  EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96

Query: 289 ELNKTK 294
              + +
Sbjct: 97  RKKRRR 102



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 18/80 (22%), Positives = 42/80 (52%), Gaps = 10/80 (12%)

Query: 199 EERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEI 258
           EER+ KE  ++  +          E+ R +   + E +E+ ++++E++K+E+  +++ + 
Sbjct: 176 EERKEKERKERKKR----------ERNRKERKKERERKERRERKKERKKKEERKKERQKD 225

Query: 259 EDVGSDEEEEKKDGDKKKKK 278
                 E+E  K   K++KK
Sbjct: 226 RQTNWREKERGKRERKERKK 245



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 18/64 (28%), Positives = 35/64 (54%)

Query: 231 SDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEEL 290
           S+    E+E +  ++ K+E+ESE K E  +    + E +K+  +++ KK K+    +EE 
Sbjct: 36  SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95

Query: 291 NKTK 294
            + K
Sbjct: 96  ERKK 99


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 16/116 (13%)

Query: 178 EPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEE 237
           E  G G K +   +E +    EE+  KE  + H            +KER++E+ +   EE
Sbjct: 687 ERPGEGEKELAEKEEWKKRDGEEQEQKEREQGH------------QKERNQEMEEGGEEE 734

Query: 238 KEDKEEEK----EKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEE 289
             + EEE+    E+EEKE E K E E    + E EK++G++KK+++  ++   +EE
Sbjct: 735 HGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 24/66 (36%), Positives = 40/66 (60%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
           E+E ++E  + E EE E +EEE E EE+E E K E E    + EEE ++G+ + +++  E
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884

Query: 283 KYIDQE 288
              ++E
Sbjct: 885 GEGEEE 890



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 28/103 (27%), Positives = 57/103 (55%), Gaps = 8/103 (7%)

Query: 223  EKERDKEVSDDEAEEKEDKEEEKE---KEEKESEDKPEIEDV-----GSDEEEEKKDGDK 274
            E E ++E  ++E EE+ + EEE E   +EE+E E + E+E       G +EE E++  ++
Sbjct: 987  EGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEER 1046

Query: 275  KKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLT 317
            +K+ + +E   ++EE  + +  +    ++    + GE YK ++
Sbjct: 1047 EKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVS 1089



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 26/92 (28%), Positives = 49/92 (53%), Gaps = 2/92 (2%)

Query: 223  EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
            E+   +E  + E EE+E+ E E E E +E E + E E+   + EE +K+G+ ++ ++ +E
Sbjct: 1001 EEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNRE 1060

Query: 283  KYIDQEELNKTKPIWTRNPDDITNEEYGEFYK 314
            +  ++EE  K +       +    EEY +  K
Sbjct: 1061 E--EEEEEGKYQETGEEENERQDGEEYKKVSK 1090



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 23/63 (36%), Positives = 41/63 (65%), Gaps = 5/63 (7%)

Query: 223  EKERDKEVSDDEAEEKEDK---EEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDK-KKKK 278
            E E ++E  ++E EE+E +   EE +   E+E E++ + ++ G +EE E++DG++ KK  
Sbjct: 1031 EGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETG-EEENERQDGEEYKKVS 1089

Query: 279  KIK 281
            KIK
Sbjct: 1090 KIK 1092



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 27/75 (36%), Positives = 44/75 (58%), Gaps = 2/75 (2%)

Query: 223  EKERDKEVSDDEAE-EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 281
            E E + EV  +E E E E++E E+E EE+E E + E E+  + EEEE+++G  ++  + +
Sbjct: 1018 EGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGE-ENRRNREEEEEEEGKYQETGEEE 1076

Query: 282  EKYIDQEELNKTKPI 296
             +  D EE  K   I
Sbjct: 1077 NERQDGEEYKKVSKI 1091



 Score = 38.1 bits (87), Expect = 0.029
 Identities = 20/53 (37%), Positives = 32/53 (60%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKK 275
           E E  K   ++E EE E +EEE E EE+E E + E  +   +EE E+ +G+++
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEE 870



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 22/68 (32%), Positives = 40/68 (58%), Gaps = 3/68 (4%)

Query: 222 VEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 281
           VE ER+KE  + + EE+  KEE+ E+E  + E +   E+      EEK++G + +  +++
Sbjct: 764 VEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE---EEETEGRGEEKEEGGEVEGGEVE 820

Query: 282 EKYIDQEE 289
           E   ++EE
Sbjct: 821 EGKGEREE 828



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 22/67 (32%), Positives = 38/67 (56%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
           EKE   EV   E EE + + EE+E+E +  E++ E E+   + EEE+ +G  +++ +  E
Sbjct: 807 EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE 866

Query: 283 KYIDQEE 289
              + EE
Sbjct: 867 GEEEGEE 873



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 23/68 (33%), Positives = 42/68 (61%), Gaps = 1/68 (1%)

Query: 223  EKERDKEVSDDEAEEKEDKEEEKEKE-EKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 281
            E E + E  + E EE+E + E +E+E E+E E++ E E+ G  E EE+++G+ + + + +
Sbjct: 969  EGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGE 1028

Query: 282  EKYIDQEE 289
            E   + EE
Sbjct: 1029 EGEGEGEE 1036



 Score = 36.6 bits (83), Expect = 0.085
 Identities = 22/89 (24%), Positives = 47/89 (52%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
           E++ ++E    E EE+E +   +EKEE    +  E+E+   + EEE+++G+ ++++   E
Sbjct: 784 EEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGE 843

Query: 283 KYIDQEELNKTKPIWTRNPDDITNEEYGE 311
           +   + E  + +       ++   EE GE
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 21/66 (31%), Positives = 39/66 (59%), Gaps = 1/66 (1%)

Query: 223  EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
            E E + E   +E E  E +EEE E E +E E + E E+ G  EEE + +G+++++ +++ 
Sbjct: 965  EGEEEGEGEGEEGEG-EGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEG 1023

Query: 283  KYIDQE 288
            +   +E
Sbjct: 1024 EVEGEE 1029



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 37/169 (21%), Positives = 70/169 (41%), Gaps = 18/169 (10%)

Query: 149 TVITKHNDDEQYAW--ESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKE- 205
           T +T+++D ++Y    E   G +       G  M +    I    +++ E  EE+   E 
Sbjct: 536 TALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAED 595

Query: 206 -----IVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIED 260
                I ++  +     + +   ++   E+  D+  +K +  E K K   E+ED PE   
Sbjct: 596 SKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRG 655

Query: 261 VGSDEE----------EEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTR 299
            G+ EE          EE++ G+K K +   E+  + E+    K  W +
Sbjct: 656 DGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKK 704



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 40/172 (23%), Positives = 73/172 (42%), Gaps = 21/172 (12%)

Query: 155 NDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFI 214
           +DD     E S G + +V      P GRG             + +E R K    K    +
Sbjct: 627 SDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEM 686

Query: 215 GYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDV----------GSD 264
             P       E +KE+++ E  +K D EE+++KE ++   K   +++          G +
Sbjct: 687 ERP------GEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEE 740

Query: 265 EE-----EEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGE 311
           EE     EE+K+G+ K++ + +E   ++E+    +    R   +   EE G+
Sbjct: 741 EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGD 792



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 20/48 (41%), Positives = 27/48 (56%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKK 270
           E E + E  + E E +E+ E E E+EE E E + E E  G +EE E K
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGK 920



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 3/66 (4%)

Query: 224 KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 283
           +E + E  ++E E + ++E E E EE+E E + E E  G  EEEE   G+ K +++ +E 
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE---GEGKGEEEGEEG 928

Query: 284 YIDQEE 289
             + EE
Sbjct: 929 EGEGEE 934



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 18/51 (35%), Positives = 31/51 (60%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGD 273
           E+E + E  ++E E + ++E E E EE+E E K E E    + E E+++G+
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 21/68 (30%), Positives = 42/68 (61%), Gaps = 2/68 (2%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEE-EEKKDGDKKKKKKIK 281
           ++E ++E   +  EE E +E E E+E++E E K E E  G +E+ EE+ D  + ++++ +
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKE-ERAGKEEKGEEEGDQGEGEEEETE 802

Query: 282 EKYIDQEE 289
            +  ++EE
Sbjct: 803 GRGEEKEE 810



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 5/66 (7%)

Query: 223 EKERDKEVSDDEAEEKEDKEE----EKEKEEKESEDKPEIEDVGSDEEEE-KKDGDKKKK 277
           E+E  +   ++E EE E +EE    E E EE+E E + E E  G  EEEE + +G+++ +
Sbjct: 850 EEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGE 909

Query: 278 KKIKEK 283
            + +E+
Sbjct: 910 GEGEEE 915



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 20/60 (33%), Positives = 37/60 (61%), Gaps = 1/60 (1%)

Query: 224  KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 283
            +E + E   +E  E E +E E E EE+E E + E E+ G +E EE+ +G+++ + + +E+
Sbjct: 958  EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGE-EEEGEEEGEEEGEGEEEGEGEGEEE 1016



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 25/74 (33%), Positives = 42/74 (56%), Gaps = 7/74 (9%)

Query: 223  EKERDKEVSDDEAE-EKEDKEEEKEKEEKESEDKPEIEDVGSD------EEEEKKDGDKK 275
            E+E + E  D E E E+E+ E E E+EE E E + E E  G +      EEE + +G+++
Sbjct: 934  EEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEE 993

Query: 276  KKKKIKEKYIDQEE 289
            + ++  E+  + EE
Sbjct: 994  EGEEEGEEEGEGEE 1007



 Score = 33.9 bits (76), Expect = 0.55
 Identities = 20/65 (30%), Positives = 38/65 (58%)

Query: 225 ERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKY 284
           E ++   + E EE+E + EE+E E +E E + E E+     EEE ++G+ +++ +  E  
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877

Query: 285 IDQEE 289
            ++EE
Sbjct: 878 GEEEE 882



 Score = 33.9 bits (76), Expect = 0.55
 Identities = 21/61 (34%), Positives = 37/61 (60%), Gaps = 1/61 (1%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
           E E ++E  + E EE E K EE E EE E E++ E  +   +EEE + +G+++ + + +E
Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEE-EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE 897

Query: 283 K 283
           +
Sbjct: 898 E 898



 Score = 33.9 bits (76), Expect = 0.55
 Identities = 18/51 (35%), Positives = 30/51 (58%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGD 273
           E E + E  + E E +E+ E E E+EE E + + E E+   + EEE+ +G+
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGE 940



 Score = 33.1 bits (74), Expect = 0.94
 Identities = 20/59 (33%), Positives = 37/59 (62%), Gaps = 4/59 (6%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKE---EKESEDKPEIEDVGSDEEEEKKDGDKKKKK 278
           E+E ++   ++E EE E + EE+E E   E+E E + E E+ G  E EE+ +G+ ++++
Sbjct: 859 EEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE-EEEGEGEGEEEGEGEGEEEE 916



 Score = 33.1 bits (74), Expect = 0.94
 Identities = 20/66 (30%), Positives = 37/66 (56%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
           E+E  +   +D   E E++E E E EE+E E + E E  G  EE E +  +++ + + +E
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992

Query: 283 KYIDQE 288
           +  ++E
Sbjct: 993 EEGEEE 998



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 1/68 (1%)

Query: 223 EKERDKEVSDDEAEEK-EDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 281
           E E ++E  + E EE+ E + EE+E E K  E+  E E  G +EE E +  D + + + +
Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE 951

Query: 282 EKYIDQEE 289
           E   + EE
Sbjct: 952 EGEWEGEE 959



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 21/52 (40%), Positives = 31/52 (59%), Gaps = 2/52 (3%)

Query: 224 KERDKEVSDDEAE-EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDK 274
           +E + E  ++E E E ED E E E+EE E E + E E  G  EEE + +G++
Sbjct: 926 EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE-EGEGEGEEEGEGEGEE 976



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 20/64 (31%), Positives = 38/64 (59%), Gaps = 3/64 (4%)

Query: 223  EKERDKEVSDDEAEEKEDK---EEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKK 279
            E E ++E  + E EE+E +   EEE E E +E E + E E+   + EEE+ + + +++ +
Sbjct: 945  EGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE 1004

Query: 280  IKEK 283
             +E+
Sbjct: 1005 GEEE 1008



 Score = 30.4 bits (67), Expect = 6.1
 Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 2/57 (3%)

Query: 223 EKERDKEVSDDEAEEKEDK--EEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKK 277
           E+E  +   ++E EE E +  EEE E E ++ E + E E+   + EEE+ +G+ +++
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEE 969


>gi|4757900 calreticulin precursor [Homo sapiens]
          Length = 417

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 26/59 (44%), Positives = 41/59 (69%), Gaps = 4/59 (6%)

Query: 222 VEKERDKEVSDDEAEE---KEDKEEEKEKEEKESEDKPEIEDVGSDEE-EEKKDGDKKK 276
           V K  +K++ D + EE   KE++E++K KEE+E+EDK + ED   DEE EE K+ D+++
Sbjct: 349 VTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 18/46 (39%), Positives = 32/46 (69%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEE 268
           E++R KE  +D+  ++E++ E+KE +E + ED+ + ED   DEEE+
Sbjct: 363 EEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 17/48 (35%), Positives = 30/48 (62%)

Query: 224 KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKD 271
           KE +++    E EE EDKE++++K+E E +++ + ED   D   + KD
Sbjct: 368 KEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKD 415



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 19/58 (32%), Positives = 34/58 (58%), Gaps = 10/58 (17%)

Query: 199 EERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKP 256
           EE+R+KE  +   +          ++E + E  +D+ ++ ED+E+E++KEE E ED P
Sbjct: 363 EEQRLKEEEEDKKR----------KEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVP 410



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 15/54 (27%), Positives = 39/54 (72%), Gaps = 1/54 (1%)

Query: 236 EEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEE 289
           ++ +DK++E+++ ++E EDK   E+  ++++E+ +D D+ ++ + ++K  D+EE
Sbjct: 355 KQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDE-EDKEEDEEE 407



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 16/47 (34%), Positives = 30/47 (63%), Gaps = 4/47 (8%)

Query: 223 EKERDKEVSDDEAEEKEDKEE----EKEKEEKESEDKPEIEDVGSDE 265
           E+E  K   ++EAE+KED E+    E+++E+KE +++ ++     DE
Sbjct: 370 EEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 1/53 (1%)

Query: 238 KEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKD-GDKKKKKKIKEKYIDQEE 289
           K  +++ K+K+++E   K E ED    EEEE +D  D + K + +E   D+EE
Sbjct: 351 KAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEE 403


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)

Query: 191 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 250
           K D ++Y E  R+   V++    +G+   L    +        +A  KE++EEE+E EE+
Sbjct: 689 KRDLSDYRERARLLNRVRR----VGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEE 744

Query: 251 ESEDKPEIEDVGSDEEEEKKDGDKKKK 277
           E ED+ E E+   +EEEE+++ +++++
Sbjct: 745 EEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 16/41 (39%), Positives = 32/41 (78%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGS 263
           E+E ++E  ++E E++E++EEE+E+EE+E E++ E E+  +
Sbjct: 734 EEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAA 774



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 19/54 (35%), Positives = 33/54 (61%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKK 276
           E+E ++E  +DE EE+E++EEE+E+EE+E E++     V   E    + G   +
Sbjct: 738 EEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSE 791



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 19/60 (31%), Positives = 37/60 (61%), Gaps = 5/60 (8%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDV-----GSDEEEEKKDGDKKKK 277
           E+E + E  ++E EE+E++EEE+E+EE+E+     + +V     GS  E  ++  D+ ++
Sbjct: 743 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQE 802


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 26/69 (37%), Positives = 46/69 (66%), Gaps = 6/69 (8%)

Query: 223 EKERDKEVSDDEAE-----EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKK 277
           +K++DKE S DE E     +K+ K++EK++E K   DK +++ V  D +EE++  D +K+
Sbjct: 379 KKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK-DVKQVTRDYDEEEQGYDSEKE 437

Query: 278 KKIKEKYID 286
           KK ++K I+
Sbjct: 438 KKEEKKPIE 446



 Score = 36.6 bits (83), Expect = 0.085
 Identities = 18/74 (24%), Positives = 39/74 (52%), Gaps = 8/74 (10%)

Query: 236 EEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEE------ 289
           E+K+DK++E+ ++E+E     + +    +++ E+K    K  K++   Y ++E+      
Sbjct: 377 EKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEK 436

Query: 290 --LNKTKPIWTRNP 301
               + KPI T +P
Sbjct: 437 EKKEEKKPIETGSP 450



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 14/83 (16%)

Query: 228 KEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQ 287
           +++S   +  +  KE++K+K+++ S D            E ++   KKKK K KEK  D+
Sbjct: 363 RKLSRSPSPRRHKKEKKKDKDKERSRD------------ERERSTSKKKKSKDKEK--DR 408

Query: 288 EELNKTKPIWTRNPDDITNEEYG 310
           E  +++     +   D   EE G
Sbjct: 409 ERKSESDKDVKQVTRDYDEEEQG 431


>gi|4758220 XAP-5 protein [Homo sapiens]
          Length = 339

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 29/107 (27%), Positives = 60/107 (56%), Gaps = 9/107 (8%)

Query: 224 KERDKEVSDDE-AEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
           KER+K+++  E ++E + K E+  ++E++ E K +I  +    EEE++ G+++++  + E
Sbjct: 82  KEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYE 141

Query: 283 KYIDQEELNKTKPIWTRNPDDITN--------EEYGEFYKSLTNDWE 321
           + +++EE+   K    +NPD  T+        EE     + L  +WE
Sbjct: 142 EEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWE 188


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 33/161 (20%)

Query: 225 ERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEK--------KDGDKKK 276
           + D E SD+E EE+E++EEE+  + +E ED  ++++   D+EEE         KDGDK  
Sbjct: 437 DEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSP 496

Query: 277 KKKIK---EKYIDQ---------EELNKTKPIWTR-------NPDDITNEEYGEFYKSLT 317
              ++   EK ++          E+ NK + +           P  I  E  GE  + LT
Sbjct: 497 MSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELT 556

Query: 318 NDWEDHLAVKHFSVEGQLEFRAL-LFVPRRAPFDLFENRKK 357
            + E  +     S   +LE  AL L  P     D+  +RK+
Sbjct: 557 LEEESPV-----SQLFELEIEALPLDTPSSVETDISSSRKQ 592


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 33/161 (20%)

Query: 225 ERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEK--------KDGDKKK 276
           + D E SD+E EE+E++EEE+  + +E ED  ++++   D+EEE         KDGDK  
Sbjct: 437 DEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSP 496

Query: 277 KKKIK---EKYIDQ---------EELNKTKPIWTR-------NPDDITNEEYGEFYKSLT 317
              ++   EK ++          E+ NK + +           P  I  E  GE  + LT
Sbjct: 497 MSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELT 556

Query: 318 NDWEDHLAVKHFSVEGQLEFRAL-LFVPRRAPFDLFENRKK 357
            + E  +     S   +LE  AL L  P     D+  +RK+
Sbjct: 557 LEEESPV-----SQLFELEIEALPLDTPSSVETDISSSRKQ 592


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 33/161 (20%)

Query: 225 ERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEK--------KDGDKKK 276
           + D E SD+E EE+E++EEE+  + +E ED  ++++   D+EEE         KDGDK  
Sbjct: 449 DEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSP 508

Query: 277 KKKIK---EKYIDQ---------EELNKTKPIWTR-------NPDDITNEEYGEFYKSLT 317
              ++   EK ++          E+ NK + +           P  I  E  GE  + LT
Sbjct: 509 MSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELT 568

Query: 318 NDWEDHLAVKHFSVEGQLEFRAL-LFVPRRAPFDLFENRKK 357
            + E  +     S   +LE  AL L  P     D+  +RK+
Sbjct: 569 LEEESPV-----SQLFELEIEALPLDTPSSVETDISSSRKQ 604


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 4/119 (3%)

Query: 186 VILHLKEDQTEYLE--ERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEE 243
           V  H+K    E ++  E+  KE V    Q     +T  V +E +KE  ++E +E+E  EE
Sbjct: 432 VSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEE 491

Query: 244 EKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPD 302
           E+ +  +E    P  E+  S E+E K    ++ K   + K  ++EE     P   ++P+
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK--SPAEVKSPE 548



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 1/91 (1%)

Query: 222 VEK-ERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKI 280
           VEK E++  + +++ EE +  EE  E+EEKE++++   E+ G +EEE +   ++ K    
Sbjct: 447 VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPA 506

Query: 281 KEKYIDQEELNKTKPIWTRNPDDITNEEYGE 311
           +E    ++E         ++P +  + E  E
Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEKEE 537



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 35/134 (26%), Positives = 58/134 (43%), Gaps = 5/134 (3%)

Query: 190 LKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEA----EEKEDKEEEK 245
           LKED     +E   KE VK   +    P  + V KE  K+  +++A    + +E K+ +K
Sbjct: 803 LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKV-KEPPKKAEEEKAPATPKTEEKKDSKK 861

Query: 246 EKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDIT 305
           E+  K+   KP++E+      E+ K+   + KK+  E         K  P      +D  
Sbjct: 862 EEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK 921

Query: 306 NEEYGEFYKSLTND 319
            +E  E  K   +D
Sbjct: 922 PKEKTEVAKKEPDD 935



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 25/115 (21%), Positives = 51/115 (44%)

Query: 194 QTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESE 253
           + E  +E ++KE  KK  +          EK+  K+    + E  + K EEK++   E  
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885

Query: 254 DKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEE 308
            + ++E    + E++KK    +K+   K +  +  +  +   +  + PDD   +E
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 5/77 (6%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPE---IEDVGSDEEEEKKDGDKK--KK 277
           EK +     D +A EKE  ++E+ K   + E+KP+   +++     EEEK     K  +K
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK 856

Query: 278 KKIKEKYIDQEELNKTK 294
           K  K++   ++E  K K
Sbjct: 857 KDSKKEEAPKKEAPKPK 873



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 21/90 (23%), Positives = 41/90 (45%)

Query: 219  TLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKK 278
            T   +KE D   + + ++  E KE   EK++ + E   + E+    E + K+D     K+
Sbjct: 926  TEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985

Query: 279  KIKEKYIDQEELNKTKPIWTRNPDDITNEE 308
              K K    E+ + T    ++ P+  T ++
Sbjct: 986  PSKPKAEKAEKSSSTDQKDSKPPEKATEDK 1015



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 12/85 (14%)

Query: 222 VEKERDKEVSDDEAEEKEDKEE----EKE-------KEEKESEDKPEIEDVGSDEEEEKK 270
           VEK ++ +V + + EE EDK++    EKE       KE+ + ++K E+     D+ + K+
Sbjct: 882 VEKPKESKV-EAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940

Query: 271 DGDKKKKKKIKEKYIDQEELNKTKP 295
                +KK+   +  D +E    KP
Sbjct: 941 PSKPAEKKEAAPEKKDTKEEKAKKP 965



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 3/75 (4%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEE---EKKDGDKKKKKK 279
           E ++     + EA  K + +E+ + +EK    K E +D  + E     EKK+   +KK  
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT 957

Query: 280 IKEKYIDQEELNKTK 294
            +EK    EE  KT+
Sbjct: 958 KEEKAKKPEEKPKTE 972



 Score = 30.4 bits (67), Expect = 6.1
 Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 6/65 (9%)

Query: 224 KERDK-EVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 282
           K ++K EV+  E ++ + KE  K  E+KE+   PE +D    +EE+ K  ++K K + K 
Sbjct: 921 KPKEKTEVAKKEPDDAKAKEPSKPAEKKEAA--PEKKDT---KEEKAKKPEEKPKTEAKA 975

Query: 283 KYIDQ 287
           K  D+
Sbjct: 976 KEDDK 980



 Score = 30.0 bits (66), Expect = 8.0
 Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 14/81 (17%)

Query: 223  EKERDKEVSDDEAEEKE------------DKEEEKEKEEKESEDKPEIEDVGSDEEE--E 268
            EK    +   D+A+ KE            +K++ KE++ K+ E+KP+ E    ++++   
Sbjct: 924  EKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS 983

Query: 269  KKDGDKKKKKKIKEKYIDQEE 289
            K+    K +K  K    DQ++
Sbjct: 984  KEPSKPKAEKAEKSSSTDQKD 1004


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 24/70 (34%), Positives = 39/70 (55%)

Query: 232 DDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELN 291
           +DE EE+E +EEE+E EE+E ED+ E E+   +EEEE +   + +K     + I      
Sbjct: 361 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG 420

Query: 292 KTKPIWTRNP 301
           +  P+ +  P
Sbjct: 421 EPAPVLSSPP 430



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 2/91 (2%)

Query: 215 GYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDK 274
           G+ +   +    D E  ++E E +E++EE +E+EE++ E++ E E+   +EEE ++ G  
Sbjct: 347 GFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEE--EEEEEPQQRGQG 404

Query: 275 KKKKKIKEKYIDQEELNKTKPIWTRNPDDIT 305
           +K      K +D         + +  P D++
Sbjct: 405 EKSATPSRKILDPNTGEPAPVLSSPPPADVS 435


>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
           isoform b [Homo sapiens]
          Length = 1176

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 3/77 (3%)

Query: 234 EAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK---YIDQEEL 290
           E EE+E++EEE+E+EE+E E++ E E+ G+  +     G +K KKK ++         + 
Sbjct: 300 EEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKR 359

Query: 291 NKTKPIWTRNPDDITNE 307
            K +P   + P  ++N+
Sbjct: 360 RKREPPRAKEPRGVSND 376


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 22/58 (37%), Positives = 44/58 (75%), Gaps = 4/58 (6%)

Query: 231 SDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQE 288
           SD+E EE+E++EEE+E+EE+E ED  E E    ++EEE  + +++++++ +E++ ++E
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEE----EDEEEYFEEEEEEEEEFEEEFEEEE 939



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 22/61 (36%), Positives = 45/61 (73%), Gaps = 1/61 (1%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESED-KPEIEDVGSDEEEEKKDGDKKKKKKIK 281
           E+E ++E  +D  EE+ED+EE  E+EE+E E+ + E E+   + EEE+++ D++++++++
Sbjct: 899 EEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958

Query: 282 E 282
           E
Sbjct: 959 E 959



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 23/74 (31%), Positives = 50/74 (67%), Gaps = 2/74 (2%)

Query: 218 ITLFVEKERDKEVSDDEAEEKEDKEEEKEKE--EKESEDKPEIEDVGSDEEEEKKDGDKK 275
           +T+      D+E  ++E EE+E++EEE+E+E  E+E ED+ E  +   +EEEE ++  ++
Sbjct: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEE 937

Query: 276 KKKKIKEKYIDQEE 289
           ++ +++E+  +++E
Sbjct: 938 EEGELEEEEEEEDE 951



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 23/77 (29%), Positives = 54/77 (70%), Gaps = 4/77 (5%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKESE---DKPEIEDVGSDEEEEKKDGDKKKKKK 279
           E+E ++E  ++E EE+E++EE+ E+EE++ E   ++ E E+   +EE E+++G+ +++++
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947

Query: 280 IKEKYIDQEELNKTKPI 296
            +E   ++EEL + + +
Sbjct: 948 -EEDEEEEEELEEVEDL 963



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 23/50 (46%), Positives = 34/50 (68%), Gaps = 1/50 (2%)

Query: 221 FVEKERDKEVSDDEAEEKEDK-EEEKEKEEKESEDKPEIEDVGSDEEEEK 269
           F E+E D+E   +E EE+E++ EEE E+EE E E++ E ED   +EE E+
Sbjct: 910 FEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEE 959



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 20/79 (25%)

Query: 191 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 250
           +ED+ EY EE   +E                  +E ++E  ++E E +E++EEE E+EE+
Sbjct: 914 EEDEEEYFEEEEEEE------------------EEFEEEFEEEEGELEEEEEEEDEEEEE 955

Query: 251 ESEDKPEIE--DVGSDEEE 267
           E E+  ++E    G + EE
Sbjct: 956 ELEEVEDLEFGTAGGEVEE 974



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 8/71 (11%)

Query: 191 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 250
           +E++ E  EE   +E  +   ++       F E+E ++E  ++E EE+E + EE+E EE+
Sbjct: 898 EEEEEEEEEEEDFEEEEEDEEEY-------FEEEEEEEEEFEEEFEEEEGELEEEE-EEE 949

Query: 251 ESEDKPEIEDV 261
           + E++ E+E+V
Sbjct: 950 DEEEEEELEEV 960



 Score = 36.6 bits (83), Expect = 0.085
 Identities = 20/70 (28%), Positives = 41/70 (58%)

Query: 242 EEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNP 301
           +EE+E+EE+E E++ E E+   D EEE++D ++  +++ +E+   +EE  + +       
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946

Query: 302 DDITNEEYGE 311
           ++   EE  E
Sbjct: 947 EEEDEEEEEE 956



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 22/80 (27%), Positives = 43/80 (53%)

Query: 193 DQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKES 252
           D+ E  EE   +E  ++  +   +      E+E  +E  ++E E +E+ EEE+ + E+E 
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946

Query: 253 EDKPEIEDVGSDEEEEKKDG 272
           E++ E E+   +E E+ + G
Sbjct: 947 EEEDEEEEEELEEVEDLEFG 966


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 33/144 (22%), Positives = 64/144 (44%), Gaps = 19/144 (13%)

Query: 151  ITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKH 210
            ++  + ++    ES      +   D   P  R  K    L+E+Q  Y ++++ + I    
Sbjct: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA-ELEENQRSYKQKKKRRRI---- 1390

Query: 211  SQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKK 270
                          +  ++ S +     E++EEEKE+EE+E E++ E E+  +D+ +   
Sbjct: 1391 --------------KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1436

Query: 271  DGDKKKKKKIKEKYIDQEELNKTK 294
             G KK +K +K+  +  E  N  K
Sbjct: 1437 KGRKKIRKILKDDKLRTETQNALK 1460



 Score = 33.1 bits (74), Expect = 0.94
 Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 3/92 (3%)

Query: 222  VEKERDKEVSDDEAEEKEDKEEEKEKEEKESED--KPEIEDVGSDEEEEKKDGDKKKKKK 279
            V+    ++VS +++E+ + +E    +E  ESED  +P        E EE +   K+KKK+
Sbjct: 1328 VKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1387

Query: 280  IKEKYIDQEELNKTKPIWTRNPDDITNEEYGE 311
             + K + ++  ++ K       ++   EE  E
Sbjct: 1388 RRIK-VQEDSSSENKSNSEEEEEEKEEEEEEE 1418



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 15/65 (23%), Positives = 35/65 (53%), Gaps = 1/65 (1%)

Query: 220  LFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKK 279
            + +E+ +    SD++    ++ EE K++  K++E+ P  E+  +    E  D D ++ KK
Sbjct: 1237 MLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSES-DSDSEESKK 1295

Query: 280  IKEKY 284
             + ++
Sbjct: 1296 PRYRH 1300


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 33/144 (22%), Positives = 64/144 (44%), Gaps = 19/144 (13%)

Query: 151  ITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKH 210
            ++  + ++    ES      +   D   P  R  K    L+E+Q  Y ++++ + I    
Sbjct: 1374 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA-ELEENQRSYKQKKKRRRI---- 1428

Query: 211  SQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKK 270
                          +  ++ S +     E++EEEKE+EE+E E++ E E+  +D+ +   
Sbjct: 1429 --------------KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1474

Query: 271  DGDKKKKKKIKEKYIDQEELNKTK 294
             G KK +K +K+  +  E  N  K
Sbjct: 1475 KGRKKIRKILKDDKLRTETQNALK 1498



 Score = 33.1 bits (74), Expect = 0.94
 Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 3/92 (3%)

Query: 222  VEKERDKEVSDDEAEEKEDKEEEKEKEEKESED--KPEIEDVGSDEEEEKKDGDKKKKKK 279
            V+    ++VS +++E+ + +E    +E  ESED  +P        E EE +   K+KKK+
Sbjct: 1366 VKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1425

Query: 280  IKEKYIDQEELNKTKPIWTRNPDDITNEEYGE 311
             + K + ++  ++ K       ++   EE  E
Sbjct: 1426 RRIK-VQEDSSSENKSNSEEEEEEKEEEEEEE 1456



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 15/65 (23%), Positives = 35/65 (53%), Gaps = 1/65 (1%)

Query: 220  LFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKK 279
            + +E+ +    SD++    ++ EE K++  K++E+ P  E+  +    E  D D ++ KK
Sbjct: 1275 MLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSES-DSDSEESKK 1333

Query: 280  IKEKY 284
             + ++
Sbjct: 1334 PRYRH 1338


>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
           sapiens]
          Length = 482

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 29/118 (24%), Positives = 68/118 (57%), Gaps = 12/118 (10%)

Query: 191 KEDQTEYLEERRIKE--IVKKHSQFIGYPITLFVEKERD----KEVSDDEAEEKEDKEEE 244
           +E++  ++EE++++E  ++++  Q +     L  +K ++    K+  ++ A+++++++E 
Sbjct: 46  EEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQER 105

Query: 245 KEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPD 302
           K KE+ E + + E       EEEE+K  +KK+K++  +K +DQ E         +NP+
Sbjct: 106 KLKEQWEEQQRKE------REEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPE 157



 Score = 33.5 bits (75), Expect = 0.72
 Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 4/104 (3%)

Query: 223 EKERDKEVSDDEAEEKEDKEEEKEKEEKE---SEDKPEIE-DVGSDEEEEKKDGDKKKKK 278
           E+E D  + + + EE++  E E+++  +E    E K + E  +  ++EE  K   +++++
Sbjct: 46  EEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQER 105

Query: 279 KIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWED 322
           K+KE++ +Q+   + +    R       E   +      N+ E+
Sbjct: 106 KLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELEN 149



 Score = 30.8 bits (68), Expect = 4.7
 Identities = 35/149 (23%), Positives = 65/149 (43%), Gaps = 16/149 (10%)

Query: 446 KLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANS 505
           K+   E   ++K  + L +        E+  L+D     KE ++  +      + Q+   
Sbjct: 6   KMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFI----EEQQLEEE 61

Query: 506 AFVER----------LRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDE 555
             +ER          LR+   +  + I+   E   ++ +E + + L    +E  +  E E
Sbjct: 62  KLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQ-QRKERE 120

Query: 556 EEKKKQEEKKTKFENLCKIMKDILEKKVE 584
           EE++K++EKK K E L K M D  E ++E
Sbjct: 121 EEEQKRQEKKEKEEALQK-MLDQAENELE 148



 Score = 30.0 bits (66), Expect = 8.0
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 226 RDKEVSDDEAEEKEDKEEEKEKEEK--ESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 283
           RD  +S  E EE    EE++ +EEK  E E +   E+    E++ +++   KK+K+   K
Sbjct: 38  RDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAK 97

Query: 284 YIDQEELNKTKPIWTRNPDDITNEE 308
              +E+  K K  W         EE
Sbjct: 98  KRQEEQERKLKEQWEEQQRKEREEE 122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,850,454
Number of Sequences: 37866
Number of extensions: 1331684
Number of successful extensions: 42988
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 724
Number of HSP's successfully gapped in prelim test: 632
Number of HSP's that attempted gapping in prelim test: 12792
Number of HSP's gapped (non-prelim): 14438
length of query: 732
length of database: 18,247,518
effective HSP length: 110
effective length of query: 622
effective length of database: 14,082,258
effective search space: 8759164476
effective search space used: 8759164476
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.