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Search of human proteins with 154090959
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154090959 hypothetical protein LOC55747 [Homo sapiens]
(1253 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154090959 hypothetical protein LOC55747 [Homo sapiens] 2469 0.0
gi|54124343 hypothetical protein LOC387680 [Homo sapiens] 2443 0.0
gi|59814411 hypothetical protein LOC253725 [Homo sapiens] 2351 0.0
gi|169190542 PREDICTED: hypothetical protein [Homo sapiens] 604 e-172
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 64 1e-09
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 63 2e-09
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 62 3e-09
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 62 4e-09
gi|217330641 IWS1 homolog [Homo sapiens] 61 6e-09
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 60 1e-08
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 60 1e-08
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 58 5e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 58 5e-08
gi|217035154 RCSD domain containing 1 [Homo sapiens] 57 1e-07
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 57 1e-07
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 56 2e-07
gi|55741677 SET domain containing 1A [Homo sapiens] 55 3e-07
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 55 5e-07
gi|104526627 triadin [Homo sapiens] 54 7e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 54 9e-07
gi|87299628 biorientation of chromosomes in cell division 1-like... 53 2e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 53 2e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 53 2e-06
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 52 5e-06
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 52 5e-06
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 52 5e-06
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 51 6e-06
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 51 8e-06
gi|24415404 MDN1, midasin homolog [Homo sapiens] 50 2e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 49 3e-05
>gi|154090959 hypothetical protein LOC55747 [Homo sapiens]
Length = 1253
Score = 2469 bits (6399), Expect = 0.0
Identities = 1253/1253 (100%), Positives = 1253/1253 (100%)
Query: 1 MPRLSGKSVRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAF 60
MPRLSGKSVRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAF
Sbjct: 1 MPRLSGKSVRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAF 60
Query: 61 EQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEE 120
EQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEE
Sbjct: 61 EQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEE 120
Query: 121 GSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKE 180
GSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKE
Sbjct: 121 GSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKE 180
Query: 181 EEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKE 240
EEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKE
Sbjct: 181 EEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKE 240
Query: 241 RRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAG 300
RRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAG
Sbjct: 241 RRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAG 300
Query: 301 ASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPT 360
ASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPT
Sbjct: 301 ASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPT 360
Query: 361 GLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDE 420
GLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDE
Sbjct: 361 GLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDE 420
Query: 421 NKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPT 480
NKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPT
Sbjct: 421 NKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPT 480
Query: 481 SVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNI 540
SVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNI
Sbjct: 481 SVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNI 540
Query: 541 PASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVS 600
PASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVS
Sbjct: 541 PASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVS 600
Query: 601 LLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVES 660
LLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVES
Sbjct: 601 LLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVES 660
Query: 661 AKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEE 720
AKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEE
Sbjct: 661 AKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEE 720
Query: 721 DKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKT 780
DKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKT
Sbjct: 721 DKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKT 780
Query: 781 KLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEK 840
KLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEK
Sbjct: 781 KLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEK 840
Query: 841 GIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAF 900
GIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAF
Sbjct: 841 GIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAF 900
Query: 901 PSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRL 960
PSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRL
Sbjct: 901 PSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRL 960
Query: 961 AAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPV 1020
AAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPV
Sbjct: 961 AAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPV 1020
Query: 1021 PGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAK 1080
PGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAK
Sbjct: 1021 PGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAK 1080
Query: 1081 SPMFPALGEASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQKVKKNETKSNSQQDVI 1140
SPMFPALGEASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQKVKKNETKSNSQQDVI
Sbjct: 1081 SPMFPALGEASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQKVKKNETKSNSQQDVI 1140
Query: 1141 LTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAK 1200
LTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAK
Sbjct: 1141 LTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAK 1200
Query: 1201 SIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1253
SIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ
Sbjct: 1201 SIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1253
>gi|54124343 hypothetical protein LOC387680 [Homo sapiens]
Length = 1341
Score = 2443 bits (6331), Expect = 0.0
Identities = 1240/1244 (99%), Positives = 1240/1244 (99%)
Query: 10 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 69
RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN
Sbjct: 98 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 157
Query: 70 SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS 129
SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS
Sbjct: 158 SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS 217
Query: 130 IVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE 189
IVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE
Sbjct: 218 IVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE 277
Query: 190 NTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE 249
NTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE
Sbjct: 278 NTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE 337
Query: 250 DNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSS 309
DNLF PPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSS
Sbjct: 338 DNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSS 397
Query: 310 SKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 369
SKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD
Sbjct: 398 SKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 457
Query: 370 DDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV 429
DDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV
Sbjct: 458 DDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV 517
Query: 430 TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDED 489
TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPT VSLFDDED
Sbjct: 518 TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDED 577
Query: 490 EEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLAS 549
EEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLAS
Sbjct: 578 EEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLAS 637
Query: 550 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDS 609
DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDS
Sbjct: 638 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDS 697
Query: 610 RGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR 669
GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR
Sbjct: 698 GGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR 757
Query: 670 TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII 729
TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII
Sbjct: 758 TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII 817
Query: 730 QAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS 789
QAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS
Sbjct: 818 QAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS 877
Query: 790 LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQ 849
LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQ
Sbjct: 878 LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQ 937
Query: 850 DSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH 909
DSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH
Sbjct: 938 DSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH 997
Query: 910 GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETE 969
GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETE
Sbjct: 998 GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETE 1057
Query: 970 DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFA 1029
DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFA
Sbjct: 1058 DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFA 1117
Query: 1030 KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE 1089
KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE
Sbjct: 1118 KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE 1177
Query: 1090 ASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFED 1149
ASSDDDLFQSAKPKPAKKTN FPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFED
Sbjct: 1178 ASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFED 1237
Query: 1150 DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD 1209
DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD
Sbjct: 1238 DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD 1297
Query: 1210 IFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1253
IFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ
Sbjct: 1298 IFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1341
>gi|59814411 hypothetical protein LOC253725 [Homo sapiens]
Length = 1318
Score = 2351 bits (6092), Expect = 0.0
Identities = 1203/1244 (96%), Positives = 1210/1244 (97%), Gaps = 23/1244 (1%)
Query: 10 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 69
RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN
Sbjct: 98 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 157
Query: 70 SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS 129
SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS
Sbjct: 158 SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS 217
Query: 130 IVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE 189
IVDTEEEKEEEESDEDFAHHSDNEQN+HTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE
Sbjct: 218 IVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEE 277
Query: 190 NTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE 249
NTRPKRSRPTSFADELAARIKGDA+GRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE
Sbjct: 278 NTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEE 337
Query: 250 DNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSS 309
DNLF PPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEA QDRQAGASVKEESSS
Sbjct: 338 DNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSS 397
Query: 310 SKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 369
SKPGKKIPAGAVSVFLGDTDVFGAASVPS+KEPQKPEQPTPRKSPYGPPPTGLFDDDDGD
Sbjct: 398 SKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGD 457
Query: 370 DDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV 429
DDDDFFSAPHSKPSKT KVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV
Sbjct: 458 DDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKV 517
Query: 430 TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDED 489
TLS SKNLKPSSETKTQKGLFSDEEDSEDLFSSQSAS LKGASLLPGKLPTSVSLFDDED
Sbjct: 518 TLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDED 577
Query: 490 EEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLAS 549
EEDNLFGGTAAKKQTL LQAQREEKAKASELSKKKASALLFSSDEE WNIPASQTHLAS
Sbjct: 578 EEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEE--WNIPASQTHLAS 635
Query: 550 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDS 609
DSRSKGEPRDSGTLQSQEAKAVKKTSLFEED+EDDLFAIAKDSQKKTQRVSLLFEDDVDS
Sbjct: 636 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDS 695
Query: 610 RGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR 669
GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR
Sbjct: 696 GGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGR 755
Query: 670 TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII 729
TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII
Sbjct: 756 TDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNII 815
Query: 730 QAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS 789
QAPQKEVGKG DPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS
Sbjct: 816 QAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGS 875
Query: 790 LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQ 849
LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSV+SFKNQKHPESIQGSKEKGIWKPETP
Sbjct: 876 LFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETP- 934
Query: 850 DSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH 909
QANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH
Sbjct: 935 --------------------QANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSH 974
Query: 910 GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETE 969
GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSE E
Sbjct: 975 GLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAE 1034
Query: 970 DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFA 1029
DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVD SPFA
Sbjct: 1035 DMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFA 1094
Query: 1030 KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE 1089
KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE
Sbjct: 1095 KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGE 1154
Query: 1090 ASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFED 1149
ASSDDDLFQSAKPKPAKKTN FPLLEDEDDLFTDQKVKKNETKS+SQQDVILTTQDIFED
Sbjct: 1155 ASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFED 1214
Query: 1150 DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD 1209
DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD
Sbjct: 1215 DIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDD 1274
Query: 1210 IFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1253
IFS+GIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ
Sbjct: 1275 IFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 1318
>gi|169190542 PREDICTED: hypothetical protein [Homo sapiens]
Length = 308
Score = 604 bits (1557), Expect = e-172
Identities = 303/308 (98%), Positives = 305/308 (99%)
Query: 946 MRGKRRPQTRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTE 1005
MRGKRRPQTRAARRLAAQESSE EDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTE
Sbjct: 1 MRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTE 60
Query: 1006 EALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAK 1065
EALAAAAAPWEGGPVPGVD SPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAK
Sbjct: 61 EALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAK 120
Query: 1066 IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQK 1125
IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTN FPLLEDEDDLFTDQK
Sbjct: 121 IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQK 180
Query: 1126 VKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADL 1185
VKKNETKS+SQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADL
Sbjct: 181 VKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADL 240
Query: 1186 TVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDD 1245
TVKPKEKSKKKVEAKSIFDDDMDDIFS+GIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDD
Sbjct: 241 TVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDD 300
Query: 1246 PLNAFGGQ 1253
PLNAFGGQ
Sbjct: 301 PLNAFGGQ 308
Score = 33.9 bits (76), Expect = 1.0
Identities = 46/195 (23%), Positives = 74/195 (37%), Gaps = 28/195 (14%)
Query: 638 LFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSS 697
LF + G +SV++ AK + V K + + E DLF S
Sbjct: 96 LFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFP-ALGEASSDDDLFQS 154
Query: 698 SSPWDKGTKPRTKT-VLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQD-- 754
+ P KP KT L ++E+D DQ + + E D + +F+D
Sbjct: 155 AKP-----KPAKKTNPFPLLEDEDDLFTDQKV---KKNETKSSSQQDVILTTQDIFEDDI 206
Query: 755 ---EELLFSHKLQKDN--------DPDVDLFAGT----KKTKLLEPSVGSLFGDDEDDDL 799
E + S K ++ D ++D+FA K+ + S+F DD DD+
Sbjct: 207 FATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDM-DDI 265
Query: 800 FSSAKSQPLVQEKKR 814
FS+ + K R
Sbjct: 266 FSTGIQAKTTKPKSR 280
Score = 31.2 bits (69), Expect = 6.5
Identities = 50/216 (23%), Positives = 81/216 (37%), Gaps = 47/216 (21%)
Query: 567 EAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPATK 626
+AK+ +L E +DDLF AK K L ED+ D LF K
Sbjct: 133 KAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDD----LF------TDQKVK 182
Query: 627 KKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQ 686
K ET S + +++ L + + + A E++K S+K TR +
Sbjct: 183 KNETKSSS---------QQDVILTTQDIFEDDIFATEAIK-------PSQK----TREKE 222
Query: 687 ETVKHS------DLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGR 740
+T++ + D+F+ + K + S+FD++ D + I K
Sbjct: 223 KTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTK------ 276
Query: 741 DPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAG 776
PKS E F HK+ D ++ F G
Sbjct: 277 -----PKSRSAQAAPEPRFEHKVSNIFDDPLNAFGG 307
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 63.5 bits (153), Expect = 1e-09
Identities = 156/743 (20%), Positives = 273/743 (36%), Gaps = 94/743 (12%)
Query: 129 SIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIE 188
++ T++ E + S+ + H +D + Q D E + ++ A +E +D+ +++
Sbjct: 334 ALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQL-REYQDLLNVK 392
Query: 189 ENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSG---------------EAKPRK 233
+ + + RI + P +LP G E K +
Sbjct: 393 MALDIEIAAYRKLLEGEECRIGFGPI------PFSLPEGLPKIPSVSTHIKVKSEEKIKV 446
Query: 234 TLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEA 293
K +KE + E+ T +E+ G GG+ ++E E + T++
Sbjct: 447 VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGE---EEEAEGGEEETKS 503
Query: 294 PQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKS 353
P +A + KE S K K PA A S + A S +K P+K + P ++
Sbjct: 504 PPAEEAASPEKEAKSPVKEEAKSPAEAKS-----PEKEEAKSPAEVKSPEKAKSPAKEEA 558
Query: 354 PYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDL-FKEKAVASPE 412
PP + ++ + S +K + +S A+ E+ KE+A + E
Sbjct: 559 K-SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617
Query: 413 ATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGAS 472
A +E K+ AE K S K P+ E E E ++ S +K +
Sbjct: 618 AKSPVKEEAKSPAEVK---SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674
Query: 473 LLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSS 532
P K + V E+ K + +A+ EKAK+ + K+ S
Sbjct: 675 KSPEKAKSPVKAEAKSPEK---------AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Query: 533 DEEDQWNIPASQTHLASDSRSKGE---PRDSGTL--QSQEAKAVKKTSLFEEDEE--DDL 585
+E+ +++ + +++S + P + TL +S EAK K ++ +
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785
Query: 586 FAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEK 645
+ K+ K ++ ++D + P +P KK+E S EEEK
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKA-------PEKEIP---KKEEVKSPVK------EEEK 829
Query: 646 EAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGT 705
++ VK KK E K T E +K+ + ++ + P
Sbjct: 830 PQEVKVKEPPKKAEEEKAP----ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP--AVE 883
Query: 706 KPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRD--PDAHPK-STGVFQDEELLFSHK 762
KP+ V + +E EDK + + P+KE + DA PK T V + E K
Sbjct: 884 KPKESKVEAKKEEAEDKKK----VPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP--DDAK 937
Query: 763 LQKDNDPDVDLFAG-------TKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRV 815
++ + P A +K K E + EDD S S+P K
Sbjct: 938 AKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP----KAEK 993
Query: 816 VKKDHSVDSFKNQKHPESIQGSK 838
+K S D K+ K PE K
Sbjct: 994 AEKSSSTDQ-KDSKPPEKATEDK 1015
Score = 53.5 bits (127), Expect = 1e-06
Identities = 148/760 (19%), Positives = 272/760 (35%), Gaps = 106/760 (13%)
Query: 3 RLSGKSVRVYDEEVEEPVLKAEAEKTEQEKTREQKEV--DLIPKVQEAVNYGLQVLDSAF 60
+++ ++R EE+ E + +A TE E + K+ ++++ + A
Sbjct: 305 KVNTDAMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQADIASYQEAI 364
Query: 61 EQLDIKAGNSDSE--------EDDANGRVEL---------ILEPKDLYID-RPLPYLIGS 102
+QLD + N+ E +D N ++ L +LE ++ I P+P+ +
Sbjct: 365 QQLDAELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPE 424
Query: 103 KL-----------FMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSD 151
L +E + + E S +E + ++ EE EEE E
Sbjct: 425 GLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKE------- 477
Query: 152 NEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTR-PKRSRPTSFADELAARIK 210
+E ++++G EEE+ E EE T+ P S E + +K
Sbjct: 478 --------AKEEEGKEEEG--------GEEEEAEGGEEETKSPPAEEAASPEKEAKSPVK 521
Query: 211 GDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGG 270
+A + E + EAK +K ++ ++P+ +E +PP+ + S
Sbjct: 522 EEA--KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK---SPPEAKSPEKEEAKSPA 576
Query: 271 GLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDV 330
+ S K EE+ EA +A + VKEE+ S PA A S +
Sbjct: 577 EVKSPEKAK-SPAKEEAKSPAEAKSPEKAKSPVKEEAKS-------PAEAKSPVKEE--- 625
Query: 331 FGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQS 390
A S +K P+K + PT ++ P + ++ + S ++ K +S
Sbjct: 626 --AKSPAEVKSPEKAKSPT-KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS 682
Query: 391 TADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSET-KTQKGL 449
E K K+ EA + ++ + E K + +K ++T + K
Sbjct: 683 PVKA---EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSP 739
Query: 450 FSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQA 509
+E S + S +K K P D+ ++ +A
Sbjct: 740 VKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKA 799
Query: 510 ----QREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQS 565
+ + KA E+ KK+ +E+ Q A + ++ P+ S
Sbjct: 800 KSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDS 859
Query: 566 QEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPAT 625
++ +A KK + + EE A+ K + K + ED PT A
Sbjct: 860 KKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK--------KKVPTPEKEAP 911
Query: 626 KKKETVSEAPPLLFSDEEEKE---------------AQLGVKSVDKKVESAKESLKFGRT 670
K E +A P ++ +KE + + D K E AK+ + +T
Sbjct: 912 AKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKT 971
Query: 671 DVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTK 710
+ E + L++ + K SSS K +KP K
Sbjct: 972 EAKAKEDDKTLSKEPSKP-KAEKAEKSSSTDQKDSKPPEK 1010
Score = 39.3 bits (90), Expect = 0.024
Identities = 101/456 (22%), Positives = 162/456 (35%), Gaps = 48/456 (10%)
Query: 803 AKSQPLVQE-KKRVVKKDHSVDSFKNQKHP---ESIQGSKEKGIWKPETPQDSSGLAPFK 858
AKS P + +K K V S + K P E+ ++ K K ++P +P +
Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617
Query: 859 TKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLP 918
K P K A + A PT S K PE S + +++ P
Sbjct: 618 AKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSP 677
Query: 919 GSGEAGVSFDLPAQADTLHSANKSRVKMRGK-----RRPQTRAARRLAAQESSETEDMSV 973
++ V A+A + A KS VK K + P A+ +S E+
Sbjct: 678 EKAKSPVK----AEAKSPEKA-KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT 732
Query: 974 PRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAA--AAPWEGGPVPGVDRSPFAKS 1031
P + + A SP + +A + + + EA A A P +SP +
Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEE 792
Query: 1032 LGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPV---GGKAKSPMFPALG 1088
+ S +A D + E K K E P V KA+ PA
Sbjct: 793 V-KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP 851
Query: 1089 EASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQ-KVKKNETKSNSQQD--VILTTQD 1145
+ D S K + KK P +E++ + ++ K K E K +D + T +
Sbjct: 852 KTEEKKD---SKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEK 908
Query: 1146 IFEDDIFATEAIKPSQKT------------REKEKTLE-SNLFDDNIDIFADLTVKPKEK 1192
+ E KP +KT +E K E + D + KP+EK
Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968
Query: 1193 SKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQ 1228
K + +AK +DD + + +KPK+ A+
Sbjct: 969 PKTEAKAK---EDD------KTLSKEPSKPKAEKAE 995
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 62.8 bits (151), Expect = 2e-09
Identities = 180/866 (20%), Positives = 295/866 (34%), Gaps = 178/866 (20%)
Query: 119 EEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDL----- 173
E G DR +++ +E+ + + + AH + ++ + D+ + D G L
Sbjct: 943 ESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWER 1002
Query: 174 -FADSEKEEEDIEDIE--ENTRPKRSRPTS-----------------------FADELAA 207
EKE++D D E E T+P+R + S F ++
Sbjct: 1003 HHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKCFKEKKDT 1062
Query: 208 RIKG-DAVGRVDEEPTTLPSGEAKPRKTL-----KEKKERRTPSDDEEDNLFTPPKLTDE 261
+ K D G+ E +L G+ K K ++ E++ +E + + TDE
Sbjct: 1063 KEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDE 1122
Query: 262 DFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAV 321
S G SG K + +D E + R+A AS + SS K
Sbjct: 1123 SEDDRDSCMG--SGFKMGEASDLPRTDGLQEKEEGREAYASDRHRKSSDK---------- 1170
Query: 322 SVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSK 381
E QK ++P R+ G G D + F K
Sbjct: 1171 ----------------QHPERQKDKEPRDRRKDRGAADAGR------DKKEKVFEKHKEK 1208
Query: 382 PSKTG-------KVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSS 434
K K +++ D D++ K+K E + D+ K++ ++K S
Sbjct: 1209 KDKESTEKYKDRKDRASVDSTQDKKN---KQKLPEKAEKKHAAEDKAKSKHKEKSDKEHS 1265
Query: 435 KNLKPSSETKTQKGLFSD---------EEDSEDLFSSQSASKLKGASLLPGKLPTSVSLF 485
K K S +K L EDS D S S+ PG F
Sbjct: 1266 KERKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSF 1325
Query: 486 DDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQT 545
+ +D +++ CL EK K E + +S+ S D E A +
Sbjct: 1326 TEPPGDDK-------PRESACLP----EKLKEKERHRHSSSSSKKSHDRERAKKEKAEKK 1374
Query: 546 HLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFED 605
D + G +DSG + E+D L A D+ + + ED
Sbjct: 1375 EKGEDYKEGGSRKDSG-----------------QYEKDFLEA---DAYGVSYNMKADIED 1414
Query: 606 DVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEK---EAQLGVKSVDKKVESAK 662
++D LF + KK + SE P ++E K + + + KK E +
Sbjct: 1415 ELDKTIELFST--------EKKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHR 1466
Query: 663 ESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDK 722
E + + + +GLL E ++H + DK + PR +DK
Sbjct: 1467 EKWRDEKERHRDRHADGLLRHHRDELLRHHRDEQKPATRDKDSPPRVL---------KDK 1517
Query: 723 MEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKL 782
D+ K K +D K V + K+ DP G K +
Sbjct: 1518 SRDEGPRLGDAKLKEKFKDGAEKEKGDPVKMSNG---NDKVAPSKDP------GKKDARP 1568
Query: 783 LEPSVGSLFGDDEDDDL----FSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSK 838
E +G D DL F SQ ++ ++R + + + +H K
Sbjct: 1569 REKLLG-------DGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKLRHRSGDPKLK 1621
Query: 839 EKGIWKPETPQDSSGL-APFKTK---EPSTRIGKIQANLAINPAA---LLPTAASQISE- 890
EK KP GL P K +P + K++ + I PAA L P + + +
Sbjct: 1622 EKA--KPADDGRKKGLDIPAKKPPGLDPPFKDKKLKESTPIPPAAENKLHPASGADSKDW 1679
Query: 891 -----VKPVLPELAFPSSEHRRSHGL 911
+K VLP A P + R G+
Sbjct: 1680 LAGPHMKEVLP--ASPRPDQSRPTGV 1703
Score = 30.8 bits (68), Expect = 8.5
Identities = 114/591 (19%), Positives = 214/591 (36%), Gaps = 108/591 (18%)
Query: 302 SVKEESSSSKPGKKIP--AGAVSVFLGDTDV-FGAASVPSMKEPQKPEQPTPRKSPYGPP 358
S +E S+ S + P A + SV +TD F K P+ + P K Y
Sbjct: 291 SSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKATAPVKDEYE-- 348
Query: 359 PTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQT 418
FD+DD D + V + D + ++ P+ V
Sbjct: 349 ----FDEDDEQD-------------RVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSY 391
Query: 419 DENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKL 478
+N A KK +S + L +S DEED+ + +L ++LPG
Sbjct: 392 TKNNTIAPKK---ASHRILSDTS----------DEEDASVTVGTGEKLRLSAHTILPGSK 438
Query: 479 PTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQW 538
S + E++ ++ +R+++ K E+ K S SS+ E +
Sbjct: 439 TREPSNAKQQKEKNK-------------VKKKRKKETKGREVRFGKRSDKFCSSESESES 485
Query: 539 NIPA--SQTHLASDSRSKGEP-----------RDSGTLQSQEAKAVKKTSLFEEDEE--- 582
+ + L S KG P + + S + A +K + D+
Sbjct: 486 SESGEDDRDSLGSSGCLKGSPLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKH 545
Query: 583 ---DDLFAIAK------DSQKKTQRVSLLFEDDVDSRGSLFGS-PPTSVPPATKKKETVS 632
D+ I+ S + R L E D S GS S P +K+ ++S
Sbjct: 546 WRTDNWKTISSPAWSEVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLS 605
Query: 633 EAPPLLFSDEE------EKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQ 686
E S E +KE ++ K K KE G+ +++ K T +
Sbjct: 606 EKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEK---GQCSISQELKLKSFTYEYE 662
Query: 687 ETVKHSDLFSSSSPWDKGTKPRTKTV---LSLFDEEED----KMEDQNIIQAPQKEVGKG 739
++ + SD + D T+ + K + F +EE K+E++ + +K + +
Sbjct: 663 DSKQKSDK-AILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRI 721
Query: 740 RDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDL 799
+D ++++ S + +KD + K+ E + L+ ++
Sbjct: 722 KD-----------TNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKL-RLYKEERK--- 766
Query: 800 FSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQD 850
+K +P EKK +K+D + K + E + K++ +++ ++ D
Sbjct: 767 -KKSKDRPSKLEKKNDLKED-KISKEKEKIFKEDKEKLKKEKVYREDSAFD 815
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 62.0 bits (149), Expect = 3e-09
Identities = 110/489 (22%), Positives = 188/489 (38%), Gaps = 95/489 (19%)
Query: 406 KAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSE-TKTQKGLFSD-EEDSEDLFSSQ 463
KA E +VS EK T+SS K KP+ + T +K FS+ + +D S+
Sbjct: 203 KATTDEEGSVSNIATEIKDGEKSGTVSSQK--KPALKATSDEKDSFSNITREKKDGEISR 260
Query: 464 SASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEK--------- 514
+ S K +L + L +++D T + Q L+A R+EK
Sbjct: 261 TVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARG 320
Query: 515 ----AKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKA 570
K +S +K AL +SDE+D ++ + +R K + S + SQ+
Sbjct: 321 KKNGEKTRRVSSRKKPALKATSDEKDSFS---------NITRGKKDGEISRKVSSQKPPT 371
Query: 571 VKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKET 630
+K TS DEED + IA++++ K +
Sbjct: 372 LKGTS----DEEDSVLGIARENKD-----------------------------GEKSRTV 398
Query: 631 VSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK--ESLKFGRTDVAESEKEGL--LTRSAQ 686
SE PP L + +EK++ L + K E K S K + EK+ +TR +
Sbjct: 399 SSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKK 458
Query: 687 ETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHP 746
+ + S P KGT +VL + E +D + + + + +K G D
Sbjct: 459 DGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTV--SSEKPPGLKATSD--- 513
Query: 747 KSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLF------ 800
+ + +L + +KD + + KK L S D++D L+
Sbjct: 514 ------EKDSVLNIARGKKDGE-KTRTVSSRKKPALKATS------DEKDSVLYIAREKK 560
Query: 801 SSAKSQPLVQEK----KRVVKKDHSVDSFKNQKHPESIQGS----KEKGIWKPETPQDSS 852
KS+ + +K K + K+ SV + +K E I G+ K+ + +DS
Sbjct: 561 DGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSV 620
Query: 853 GLAPFKTKE 861
P + K+
Sbjct: 621 SNIPTEIKD 629
Score = 50.4 bits (119), Expect = 1e-05
Identities = 110/526 (20%), Positives = 192/526 (36%), Gaps = 97/526 (18%)
Query: 108 QEDVGLGELSSEEGSVGS--------DRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTT 159
Q+ L + EEGSV + ++ V ++++ + + ++ S+ + +
Sbjct: 197 QKQQALKATTDEEGSVSNIATEIKDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDG 256
Query: 160 QMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDE 219
++S L A S KE+ + E ++SR SF + D +
Sbjct: 257 EISRTVSSQKPPALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLN 316
Query: 220 EPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFT------------------PPKL--- 258
+GE K R+ KK + DE+D+ PP L
Sbjct: 317 IARGKKNGE-KTRRVSSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGT 375
Query: 259 TDEDFSPFGSGGGLFSGGK----------GLFDDEDEESDLFTEAPQDRQAGASVKEESS 308
+DE+ S G G K GL DE+ + A + ++ G K SS
Sbjct: 376 SDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLNIA-RGKKYGEKTKRVSS 434
Query: 309 SSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDG 368
KP + + F T + QKP P G D++D
Sbjct: 435 RKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKP-----------PALKGTSDEEDS 483
Query: 369 DDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKK 428
++ +K G+ T + ++ L KA + + +V K EK
Sbjct: 484 -------VLGIARENKDGEKSRT--VSSEKPPGL---KATSDEKDSVLNIARGKKDGEKT 531
Query: 429 VTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDE 488
T+SS K KP+ + SDE+DS + + K ++ K P ++ D E
Sbjct: 532 RTVSSRK--KPALKAT------SDEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKE 583
Query: 489 DEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQ-WNIPASQTHL 547
D N + +++++ + +S +K AL +SD++D NIP
Sbjct: 584 DSVPN-------------MATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIK-- 628
Query: 548 ASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQ 593
+ + SGT+ SQ+ A K TS+ ++D ++ KD Q
Sbjct: 629 --------DGQQSGTVSSQKQPAWKATSV-KKDSVSNIATEIKDGQ 665
Score = 50.1 bits (118), Expect = 1e-05
Identities = 97/440 (22%), Positives = 168/440 (38%), Gaps = 80/440 (18%)
Query: 273 FSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFG 332
F GL DE+ L A + ++ G + SS KP K + F T
Sbjct: 298 FDQPPGLKATRDEKDSLLNIA-RGKKNGEKTRRVSSRKKPALKATSDEKDSFSNITRGKK 356
Query: 333 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 392
+ QKP P G D++D ++ +K G+ T
Sbjct: 357 DGEISRKVSSQKP-----------PTLKGTSDEEDS-------VLGIARENKDGEKSRT- 397
Query: 393 DIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSD 452
+ ++ L KA + + +V K EK +SS K KPS E SD
Sbjct: 398 -VSSEKPPGL---KASSDEKDSVLNIARGKKYGEKTKRVSSRK--KPSLEAT------SD 445
Query: 453 EEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQRE 512
E+DS FS+ + K G +L DEED++ G + + +
Sbjct: 446 EKDS---FSNITREKKDGEISRKVSSQKPPALKGTSDEEDSVLG----------IARENK 492
Query: 513 EKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 572
+ K+ +S +K L +SDE+D + + +R K + + T+ S++ A+K
Sbjct: 493 DGEKSRTVSSEKPPGLKATSDEKDS---------VLNIARGKKDGEKTRTVSSRKKPALK 543
Query: 573 KTSLFEEDEEDDLFAIAKDSQ--KKTQRVSLLF----------EDDVDSRGS------LF 614
TS DE+D + IA++ + +K++ VS ED V + + +
Sbjct: 544 ATS----DEKDSVLYIAREKKDGEKSRTVSSQKQPALKAICDKEDSVPNMATEKKDEQIS 599
Query: 615 GSPPTSVPPATK----KKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRT 670
G+ + PA K KK++VS P + ++ + K K+S+ T
Sbjct: 600 GTVSSQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSVKKDSVSNIAT 659
Query: 671 DVAESEKEGLLTRSAQETVK 690
++ + + G ++ Q K
Sbjct: 660 EIKDGQIRGTVSPQKQSAQK 679
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 61.6 bits (148), Expect = 4e-09
Identities = 129/626 (20%), Positives = 235/626 (37%), Gaps = 87/626 (13%)
Query: 285 EESDLFTEAPQDRQAGAS-----VKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSM 339
E+ LFT +DR ++ + +SS + ++ P +++ D PS
Sbjct: 199 EQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEAD---------PSS 249
Query: 340 KEP-QKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKP-------SKTGKVQST 391
K ++ + P P K P DD D + + P K ++T
Sbjct: 250 KAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKAT 309
Query: 392 ADIFGDEEGDLFKEKAVASPEATVSQTDENKARA--EKKVTL--------SSSKNLKPSS 441
+D D ++ E TVS ++ + +KKV+L K+ SS
Sbjct: 310 SDE-KDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSS 368
Query: 442 ETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLF------ 495
+ + SD+ DS +++ L+ ++ K P + D+ED N+
Sbjct: 369 QKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDG 428
Query: 496 --GGTAAKKQTLCLQAQREEK-------------AKASELSKKKASALLFSSDEEDQWNI 540
GT + ++ L+A +EK K+ +S +K AL +SDEE
Sbjct: 429 EKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGS--- 485
Query: 541 PASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKD------SQK 594
+ S +R + S T+ S++ A K TS DE+D I + S+K
Sbjct: 486 ------VLSIARENKDGEKSRTVSSRKKPASKATS----DEKDSFSNITRGKKDGEISRK 535
Query: 595 KTQRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSV 654
+ + + D S+ G + K + SE PP L + +EK++ L +
Sbjct: 536 VSSQKPPTLKGTSDEEDSVLGIAREN-KDGEKSRTVSSEKPPGLKASSDEKDSVLNIARG 594
Query: 655 DKKVESAK--ESLKFGRTDVAESEKEGL--LTRSAQETVKHSDLFSSSSPWDKGTKPRTK 710
K E K S K + EK+ +TR ++ + S P KGT
Sbjct: 595 KKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPALKGTSDEED 654
Query: 711 TVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPD 770
+VL + E +D + + + + +K G D + + ++ + P
Sbjct: 655 SVLGIARENKDGEKSRTV--SSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTVSSQKPP 712
Query: 771 VDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKH 830
K T E SV S+ +++D + + S+ K +KD ++ + +K+
Sbjct: 713 T-----LKATSDEEDSVLSIARENKDGEKSRTVSSEKPSGLKATSAEKDSVLNIARGKKY 767
Query: 831 PESIQ--GSKEKGIWKPETPQDSSGL 854
E + S++K K + + S L
Sbjct: 768 GEKTKRVSSRKKPALKATSDEKDSVL 793
Score = 42.7 bits (99), Expect = 0.002
Identities = 96/474 (20%), Positives = 175/474 (36%), Gaps = 68/474 (14%)
Query: 108 QEDVGLGELSSEEGSVGS--------DRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTT 159
Q+ L S EEGSV S ++ V + ++ + + ++ S+ + +
Sbjct: 471 QKPPALTATSDEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDG 530
Query: 160 QMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDE 219
++S + L S++E+ + EN ++SR S + D V
Sbjct: 531 EISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKDSVLN 590
Query: 220 EPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGL 279
GE R + ++K SD+++ + D + S S KG
Sbjct: 591 IARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKP-PALKGT 649
Query: 280 FDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSM 339
D+ED + E + G + SS PG K + SV ++
Sbjct: 650 SDEEDSVLGIARE----NKDGEKSRTVSSEKPPGLKATSDEKD------------SVLNI 693
Query: 340 KEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEE 399
+K + T S PP D++D S ++ +K G+ T + ++
Sbjct: 694 ARGKKDGEKTRTVSSQKPPTLKA----TSDEEDSVLSI--ARENKDGEKSRT--VSSEKP 745
Query: 400 GDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDL 459
L KA ++ + +V K EK +SS K KP+ + SDE+DS
Sbjct: 746 SGL---KATSAEKDSVLNIARGKKYGEKTKRVSSRK--KPALKAT------SDEKDSVLY 794
Query: 460 FSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASE 519
+ + K ++ K P ++ D ED N + +++++ +
Sbjct: 795 IAREKKDGEKSRTVSSQKQPALKAICDKEDSVPN-------------MATEKKDEQISGT 841
Query: 520 LSKKKASALLFSSDEEDQ-WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVK 572
+S +K AL +SD++D NIP + + SGT+ Q+ A K
Sbjct: 842 VSSQKQPALKATSDKKDSVSNIPTEIK----------DGQQSGTVSPQKQSAQK 885
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 61.2 bits (147), Expect = 6e-09
Identities = 97/382 (25%), Positives = 142/382 (37%), Gaps = 92/382 (24%)
Query: 10 RVYDEEVEEPVLK--AEAEKTEQEKTR-EQKEVDLIPKVQEAVNYGL-----QVLDSAFE 61
++ D E EEP +++E E K R E + +PK Q + + Q DS E
Sbjct: 181 QISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENE 240
Query: 62 QLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEG 121
+L K SDSE +D E ++L P P + S E ED + S E
Sbjct: 241 ELP-KPRISDSESEDPPRHQASDSENEEL----PKPRISDS----ESEDPPRNQASDSEN 291
Query: 122 ------------SVGSDRGSIVDTEEE-----KEEEESDEDF--------------AHHS 150
S G +G D+E E K++ ESD+D + HS
Sbjct: 292 EELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHS 351
Query: 151 DNEQNRHTTQMSDEEEDDDGCDLFADSEKEEE---------------DIEDIEENTRPKR 195
D+ +R SD EE++ E E+E D ED EE K+
Sbjct: 352 DSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSED-EEKASAKK 410
Query: 196 SRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERR-------TPSDDE 248
SR S AD+ + D G+ E T E + K L +KK + S +E
Sbjct: 411 SRVVSDADDSDSDAVSDKSGK--REKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNE 468
Query: 249 EDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESS 308
E+NL FG G D+E+EE F + + + G + +E+
Sbjct: 469 EENLIA---------DIFGESG----------DEEEEEFTGFNQEDLEEEKGETQVKEAE 509
Query: 309 SSKPGKKIPAGAVSVFLGDTDV 330
S I G FL D ++
Sbjct: 510 DSDSDDNIKRGKHMDFLSDFEM 531
Score = 57.4 bits (137), Expect = 8e-08
Identities = 128/578 (22%), Positives = 205/578 (35%), Gaps = 112/578 (19%)
Query: 101 GSKLFMEQEDVGL-GELSSEEGSVGSDRGSIV-DTEEEKEEEESDEDFAHHSDNEQNRHT 158
G+ ++ D G GE E GSD GS+ +E E + E HH + +N
Sbjct: 15 GATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEP 74
Query: 159 TQM--SDEEEDDDGCDLFADSEKEE-----------EDIEDIEENTRPKRSRPTSFAD-E 204
+ SD E ++ +DSE EE ED+ ++ + +R +D E
Sbjct: 75 LNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSE 134
Query: 205 LAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFTPPKLTDEDFS 264
+ G A +E+ P+ +++ + +++P+ D E P+++D +
Sbjct: 135 NEELLNGHASDSENEDVGKHPASDSEIEEL------QKSPASDSETEDALKPQISDSESE 188
Query: 265 PFGSGGGLFSGGK-----GLFDDEDEE------SDLFTEAPQDRQAGASVKEE------- 306
S + + D E EE SD +E P QA S EE
Sbjct: 189 EPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRIS 248
Query: 307 ----------SSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKP-----EQPTPR 351
+S +++P +S + AS +E KP E P+
Sbjct: 249 DSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQ 308
Query: 352 KSPYGPPPT--------GLFDDDDGD----------DDDDFFSAPHSKPSKTGKVQSTAD 393
K P T DDD D +D F S H K S +
Sbjct: 309 KGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEE 368
Query: 394 ------IFGDEEGDLFKEKAVASPEATV--SQTDENKARAEKKVTLSSS----------- 434
+ DE+ +E+ VA +A V DE KA A+K +S +
Sbjct: 369 EHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDK 428
Query: 435 -----KNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDED 489
K + SE + K L + + +DLF S S S + +L+ S D+E+
Sbjct: 429 SGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGES---GDEEE 485
Query: 490 EEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLAS 549
EE F +++ Q + E + + + + K+ + F SD E S
Sbjct: 486 EEFTGFNQEDLEEEKGETQVKEAEDSDSDD-NIKRGKHMDFLSDFEMMLQRKKSM----- 539
Query: 550 DSRSKGEPRDSGTLQSQ-----EAKAVKKTSLFEEDEE 582
S + RD GT S A VK EED +
Sbjct: 540 -SGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQ 576
Score = 38.5 bits (88), Expect = 0.041
Identities = 85/377 (22%), Positives = 142/377 (37%), Gaps = 49/377 (12%)
Query: 439 PSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGT 498
P+S+++T+ L DSE S+ + + AS + P + D E EE
Sbjct: 168 PASDSETEDALKPQISDSE----SEEPPRHQ-ASDSENEEPPKPRMSDSESEE------- 215
Query: 499 AAKKQTLCLQAQREEKAKASELSKKKASALLFS-SDEEDQWNIPASQTH-------LASD 550
K Q +++ + +AS+ ++ S S+ ED AS + SD
Sbjct: 216 LPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISD 275
Query: 551 SRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKK-TQRVSLLFEDDVDS 609
S S+ PR+ + E + + K + + + E A DS+ + R E D DS
Sbjct: 276 SESEDPPRNQAS--DSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDS 333
Query: 610 RGSLFGSPPT-------SVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK 662
G S +KK S+ S+EEE + Q D+K +
Sbjct: 334 DRENKGEDTEMQNDSFHSDSHMDRKKFHSSD------SEEEEHKKQKMDSDEDEKEGEEE 387
Query: 663 ESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDK 722
+ K +++SE E + V +D S + DK K R KT+ S +EE K
Sbjct: 388 KVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGK-REKTIASDSEEEAGK 446
Query: 723 -MEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTK 781
+ D+ K + D + +EE L + + D + + F G +
Sbjct: 447 ELSDK-----------KNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQED 495
Query: 782 LLEPSVGSLFGDDEDDD 798
L E + + ED D
Sbjct: 496 LEEEKGETQVKEAEDSD 512
Score = 33.9 bits (76), Expect = 1.0
Identities = 105/517 (20%), Positives = 189/517 (36%), Gaps = 83/517 (16%)
Query: 717 DEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAG 776
D E D+ + N + +E+ + +D D+ + EE +N+ DV+
Sbjct: 68 DSENDEPLNLNASDSESEELHRQKDSDS--------ESEERAEPPASDSENE-DVNQHGS 118
Query: 777 TKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQG 836
+++ GS D E+++L + S ++ + D ++ QK P S
Sbjct: 119 DSESEETRKLPGS---DSENEELLNGHASDSENEDVGKHPASDSEIEEL--QKSPAS--D 171
Query: 837 SKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLP 896
S+ + KP+ S P + QA+ + N P + SE P P
Sbjct: 172 SETEDALKPQISDSESEEPP-----------RHQASDSENEEPPKPRMSDSESEELPK-P 219
Query: 897 ELAFPSSEHRRSHGLESVP--VLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQT 954
+++ SE H LP + + P + S N+ K R
Sbjct: 220 QVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESE 279
Query: 955 RAARRLAAQESSETEDMSVPR-------GPIAQWADGAISPNGHRPQLRAASGEDSTEEA 1007
R A+ SE E++ PR GP A + + + R + + S +DS E
Sbjct: 280 DPPRNQASD--SENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRE- 336
Query: 1008 LAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADL--FDSGDIFSTGTGSQSVERTKPKAK 1065
G + F HS D F S D S+ E K K
Sbjct: 337 --------NKGEDTEMQNDSF-----HSDSHMDRKKFHSSD-------SEEEEHKKQKMD 376
Query: 1066 IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNTFPLLEDED-DLFTDQ 1124
E+ G + K A + S+D+ + AKK+ +D D D +D+
Sbjct: 377 SDEDEKE---GEEEKVAKRKAAVLSDSEDE-----EKASAKKSRVVSDADDSDSDAVSDK 428
Query: 1125 KVKKNETKSNSQQDVI---LTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLF----DD 1177
K+ +T ++ ++ L+ + E D+F +++ ++ +E+ L +++F D+
Sbjct: 429 SGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDS-----ESGNEEENLIADIFGESGDE 483
Query: 1178 NIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSG 1214
+ F + E+ K + + K D D DD G
Sbjct: 484 EEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDNIKRG 520
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 60.5 bits (145), Expect = 1e-08
Identities = 127/619 (20%), Positives = 243/619 (39%), Gaps = 92/619 (14%)
Query: 285 EESDLFTEAPQDRQAGAS-----VKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSM 339
E+ LFT +DR ++ + +SS + ++ P +++ D PS
Sbjct: 199 EQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEAD---------PSS 249
Query: 340 KEP-QKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKP-------SKTGKVQST 391
K ++ + P P K P DD D + + P K ++T
Sbjct: 250 KAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKAT 309
Query: 392 ADIFGDEEGDLFKEKAVASPEATVSQTDEN--KARAEKKVTL--------SSSKNLKPSS 441
+D D ++ E TVS ++ K +KKV+L K+ SS
Sbjct: 310 SDE-KDSVSNIATEIKKGQQSGTVSPQKQSAWKVIFKKKVSLLNIATRIMGGGKSGTVSS 368
Query: 442 ETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAK 501
+ + SD+ DS +++ L+ ++ K P + D+ED N
Sbjct: 369 QKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSN-------- 420
Query: 502 KQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSG 561
+ + ++ K+ +S +K AL ++DE+D S +++A++ + + SG
Sbjct: 421 -----IATEIKDGEKSGTVSSQKQPALKATTDEKD------SVSNIATEIK---DGEKSG 466
Query: 562 TLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQ--KKTQRVS-------LLFEDDVDSRGS 612
T+ SQ+ A+ TS DEE + +IA++++ +K++ VS D+ DS
Sbjct: 467 TVSSQKPPALTATS----DEEGSVLSIARENKDGEKSRTVSSRKKPALKATSDEKDS--- 519
Query: 613 LFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDV 672
F + ++ S+ PP L +E+++ LG+ +K E ++
Sbjct: 520 -FSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENKDGEKSR---------T 569
Query: 673 AESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAP 732
SEK L S+ E ++ +K + ++ SL ++K NI +
Sbjct: 570 VSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSFSNITREK 629
Query: 733 QK-EVGKGRDPDAHPKSTGVFQDEE-LLFSHKLQKDNDPDVDLFA----GTKKTKLLEPS 786
+ E+ + P G +E+ +L + KD + + + G K T + S
Sbjct: 630 KDGEISRKVSSQKPPALKGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDS 689
Query: 787 VGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGS----KEKGI 842
V ++ +D + + S P K + K+ SV + +K E I G+ K+ +
Sbjct: 690 VLNIARGKKDGEK-TRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISGTVSCQKQPAL 748
Query: 843 WKPETPQDSSGLAPFKTKE 861
+DS P + K+
Sbjct: 749 KATSDKKDSVSNIPTEIKD 767
Score = 38.5 bits (88), Expect = 0.041
Identities = 80/366 (21%), Positives = 142/366 (38%), Gaps = 54/366 (14%)
Query: 277 KGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASV 336
K D++D S++ TE ++G ++ + +S+ + D + +V
Sbjct: 443 KATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATSDEEGSVLSIARENKDGEKSRTV 502
Query: 337 PSMKEPQ-----------------KPEQPTPRKSPYGPPPT--GLFDDDDG------DDD 371
S K+P K + RK PPT G D++D ++
Sbjct: 503 SSRKKPALKATSDEKDSFSNITRGKKDGEISRKVSSQKPPTLKGTSDEEDSVLGIARENK 562
Query: 372 DDFFSAPHSKPSKTGKVQSTAD-------IFGDEEGDLFKE---KAVASPEATVSQTDE- 420
D S S G S+A+ G ++G+ K + S EAT + D
Sbjct: 563 DGEKSRTVSSEKPPGLKASSAEKDSVLNIARGKKDGEKTKRVSSRKKPSLEATSDEKDSF 622
Query: 421 -NKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLP 479
N R +K +S + S + KG SDEEDS + ++ K ++ K P
Sbjct: 623 SNITREKKDGEISRKVS---SQKPPALKGT-SDEEDSVLGIARENKDGEKSRTVSSEKPP 678
Query: 480 TSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKA---------SELSKKKASALLF 530
+ D++D N+ G ++T + + ++ KA + ++KK +
Sbjct: 679 GLKATSDEKDSVLNIARGKKDGEKTRTVSSPKQPALKAICDKEDSVPNMATEKKDEQISG 738
Query: 531 SSDEEDQWNIPASQTHLASDSRSKGEPRD---SGTLQSQEAKAVKKTSLFEEDEEDDLFA 587
+ + Q + A+ S S E +D SGT+ SQ+ A K TS+ ++D ++
Sbjct: 739 TVSCQKQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQPAWKATSV-KKDSVSNIAT 797
Query: 588 IAKDSQ 593
KD Q
Sbjct: 798 EIKDGQ 803
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 60.1 bits (144), Expect = 1e-08
Identities = 96/595 (16%), Positives = 187/595 (31%), Gaps = 19/595 (3%)
Query: 117 SSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFAD 176
SS+ S S+ S D+ + + SD D + S++ + ++ SD + D D +D
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 177 SEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPT-----------TLP 225
S K E D D + + S + +D + ++ D + +
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685
Query: 226 SGEAKPRKTLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDE 285
S ++ E SD + + ++ + S S S D +
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745
Query: 286 ESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPS-MKEPQK 344
SD + + +S +SS S + S D+ +S S +
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805
Query: 345 PEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFK 404
+ + D + D D ++ S S S +D +
Sbjct: 806 SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS 865
Query: 405 EKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQS 464
+ + +S + S + ++ E + SS + S + SD DS + S
Sbjct: 866 DSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE 925
Query: 465 ASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKK 524
+S S S + D D D+ ++ + + +
Sbjct: 926 SSNSSDNS----NSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 525 ASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDD 584
+S SSD D + +S + +SDS + DS S + + ++ + + D
Sbjct: 982 SSDSSDSSDSSD--SSDSSDSSNSSDSSDSSDSSDSSN-SSDSSNSSDSSNSSDSSDSSD 1038
Query: 585 LFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEE 644
+ S S D DS S S + ++ E+ + SD +
Sbjct: 1039 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD 1098
Query: 645 KEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSS 699
+S+ S +D ++S + S+ + SS S
Sbjct: 1099 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153
Score = 51.6 bits (122), Expect = 5e-06
Identities = 103/643 (16%), Positives = 209/643 (32%), Gaps = 40/643 (6%)
Query: 69 NSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRG 128
NSD +D+ NG SK + + + ++ + + + G
Sbjct: 494 NSDESKDNGNGS--------------------DSKGAEDDDSDSTSDTNNSDSNGNGNNG 533
Query: 129 SIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIE 188
+ + + + + +SD + SD+ + ++ SD + D +DS+ + D D
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSS--SDSDSSDSDSSDSS 591
Query: 189 ENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSD-- 246
++ S + +D + D+ D + + S K SD
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSS 651
Query: 247 DEEDNLFTPPKLTDEDFSPFG-SGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKE 305
D D+ + D S S S D + SD + + +S +
Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711
Query: 306 ESSSSKPGKKIPAGAVSVFLGDT--------DVFGAASVPSMKEPQKPEQPTPRKSPYGP 357
S SS + + S D+ + S S + S
Sbjct: 712 SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 771
Query: 358 PPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQ 417
+ D + D +D ++ S S S + D + + +S + S
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831
Query: 418 TDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGK 477
+ ++ ++ + SS S ++ SD DS D +S +S ++
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891
Query: 478 LPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKK-ASALLFSSDEED 536
+S S + + D+ ++ + E + +S+ S +S SSD D
Sbjct: 892 SDSSDS--SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949
Query: 537 QWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKT 596
N +S + +SDS + + DS + S ++ +S + + D + S
Sbjct: 950 SSN--SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS--DSSDSSDSSDSSDSSNSSD 1005
Query: 597 QRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDK 656
S D +S S S ++ ++ ++ + SD +
Sbjct: 1006 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065
Query: 657 KVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSS 699
+S+ S +D +ES + S+ + SS S
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS 1108
Score = 50.1 bits (118), Expect = 1e-05
Identities = 133/791 (16%), Positives = 258/791 (32%), Gaps = 75/791 (9%)
Query: 107 EQEDVGLGELSSEEGSVGSDRGSIVDTEEEKE---EEESDEDFAHHSDNEQNRHTTQMSD 163
E ED G G+ EE G D + +E ++ E++ D +SD+++ D
Sbjct: 253 EDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKED 312
Query: 164 EEEDDDGCDLFADSEK------EEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRV 217
+ DG D + SE+ E+ + IE+ + + + + AVG+
Sbjct: 313 PHNEVDG-DKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKS 371
Query: 218 DEEPTTLPSGEAKPRKTLKEKKERRTPSDD-----------------EEDNLFTPPKLTD 260
++ + + R KE + +D E N+ P + ++
Sbjct: 372 QDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSE 431
Query: 261 EDFSPFGSGGGLFSGGKGL----FDDEDEESDLFTEAPQDR-QAGASVKEESSSSKPGKK 315
S G S G FDD+ + D + + A+ + +++SS G
Sbjct: 432 PGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDA 491
Query: 316 IPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDD--------- 366
S G+ G+ S + + T G G D+D
Sbjct: 492 SYNSDESKDNGN----GSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKS 547
Query: 367 -----DGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDEN 421
D D + + S S + S++D + + +S + S + ++
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607
Query: 422 KARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTS 481
++ + SS + SS++++ + DS D SS S+ + S
Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSD-----SSNS 662
Query: 482 VSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIP 541
+ D D D+ +++ + + + +SE S S+ SSD D N
Sbjct: 663 SNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSN 722
Query: 542 ASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSL 601
+S + ++ S S S + S ++ +S + + + DS + S
Sbjct: 723 SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD--SS 780
Query: 602 LFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESA 661
D DS S S ++ ++ ++ + SD + + S D +S+
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS---SDSDSSNSSDSSNSSDSS-DSS 836
Query: 662 KESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEED 721
S +D ++ S ++ SD +SS D + D +
Sbjct: 837 NSSDSSDSSDSSDG--------SDSDSSNRSDSSNSSDSSDSSDSSNSS------DSSDS 882
Query: 722 KMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTK 781
+++ + + D D+ S + S + N D + + +
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942
Query: 782 LLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKG 841
S S D + SS S +S DS + +S S
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002
Query: 842 IWKPETPQDSS 852
DSS
Sbjct: 1003 SSDSSDSSDSS 1013
Score = 39.7 bits (91), Expect = 0.018
Identities = 59/351 (16%), Positives = 120/351 (34%), Gaps = 16/351 (4%)
Query: 117 SSEEGSVGSDRGSIVDTEEEKEEEES-DEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFA 175
+S + S SD + D+ + S D ++ SD+ + +++ SD + D D +
Sbjct: 940 NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS-S 998
Query: 176 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTL 235
DS + + + + S ++ +D + D+ D ++ S ++
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSNS 1057
Query: 236 KEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQ 295
+ + SD + + + + E S S D + SD +
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117
Query: 296 DRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPY 355
+ +S +SS S + S ++ +S S + S
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 356 GPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATV 415
+ D D D S+ S S + ++D + + + +S +
Sbjct: 1178 S-------NSSDSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228
Query: 416 SQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSAS 466
S ++E+ ++ + S S N SS++ SD D D SQS S
Sbjct: 1229 SDSNESSDSSDSSDS-SDSSNSSDSSDSSDSSDSTSDSNDESD---SQSKS 1275
Score = 35.8 bits (81), Expect = 0.26
Identities = 54/343 (15%), Positives = 104/343 (30%), Gaps = 28/343 (8%)
Query: 118 SEEGSVGSDRGSIVDTEEEKEEEESDE--DFAHHSDNEQNRHTTQMSDEEEDDDGCDLFA 175
S + S SD D+ + +S + D ++ SD+ + ++ SD + D D
Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD--- 1041
Query: 176 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTL 235
+ D D +++ S +S + + + E + S +
Sbjct: 1042 --SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099
Query: 236 KEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQ 295
+ + SD + + + + + S S D E SD +
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS 1159
Query: 296 DRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPY 355
+ +S +SS S + S D+ +S S
Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS-------- 1211
Query: 356 GPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATV 415
D D D D + S S S + D + S ++T
Sbjct: 1212 --------DSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263
Query: 416 SQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSED 458
DE+ ++++ S + N S +G S+ S+D
Sbjct: 1264 DSNDESDSQSK-----SGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 58.2 bits (139), Expect = 5e-08
Identities = 112/520 (21%), Positives = 192/520 (36%), Gaps = 96/520 (18%)
Query: 8 SVRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKA 67
S ++ +VE P LK + K +E E K D +++EA+ + L + ++ +A
Sbjct: 433 SSKIQKPKVEAPKLKVQ-HKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEA 491
Query: 68 GNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDR 127
EE +A E+ + + P E+ EEG
Sbjct: 492 AEEKEEEPEAEEE-EVAAKKSPVKATAP-------------------EVKEEEGEK---- 527
Query: 128 GSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDI 187
+ EE +EEEE +++ A E+ + S E+E+ + + ++E E E+ E
Sbjct: 528 ----EEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 583
Query: 188 EENTRPKRSRPTSFADELAARIKGD----AVGRVDEEPTTLPSGEAKPRKTLKEKKERRT 243
EE ++S + +EL A K + A V + P P+ ++EK +
Sbjct: 584 EEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 643
Query: 244 PSDDEEDNLFTP-PKLTDED--------------------FSPFGSGGGLFSGGKGLFDD 282
P E+ +P PK E+ SP GKG +
Sbjct: 644 PKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKG--EQ 701
Query: 283 EDEESDLFTEAPQDRQAGASVKEESSSSKPGKK-----IPAGAVSVFLGDTDVFGAASVP 337
++EE EAP++ + KEE P KK + AV+ + T
Sbjct: 702 KEEEEKEVKEAPKEEK--VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEK 759
Query: 338 SMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGD 397
KE KP Q K G + G +++ S +K S+ + ++ G
Sbjct: 760 ETKEEGKPLQQEKEKEKAG--------GEGGSEEEG--SDKGAKGSRKEDIAVNGEVEGK 809
Query: 398 EE---------GDLFKEKAVASPEATVSQTDENKA--RAEKKVTLSSSKNLKPS------ 440
EE +EK V + +S DE K ++E+KV ++ + S
Sbjct: 810 EEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGA 869
Query: 441 ------SETKTQKGLFSDEEDSEDLFSSQSASKLKGASLL 474
S T TQK +E E L S++ K+ +++
Sbjct: 870 TKYITKSVTVTQKVEEHEETFEEKLVSTKKVEKVTSHAIV 909
Score = 39.7 bits (91), Expect = 0.018
Identities = 88/415 (21%), Positives = 156/415 (37%), Gaps = 58/415 (13%)
Query: 340 KEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEE 399
+EP+ E+ K +++G+ +++ + + K + ++E
Sbjct: 497 EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE 556
Query: 400 GDLFKEKAVASPEATVSQTD--ENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDE--ED 455
G KE+ T ++ + E +A+ EKKV + S E T++ L +D E
Sbjct: 557 GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVE-------EKSEEVATKEELVADAKVEK 609
Query: 456 SEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKA 515
E S S ++ GK P S +++ + K ++ ++ EEK
Sbjct: 610 PEKAKSPVPKSPVEEK----GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 665
Query: 516 KASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRS--KGEPRDSGTLQSQEAKAVKK 573
K S +SK +E+ + +P S A KGE ++ + +E K K
Sbjct: 666 K-SPVSKSPV-------EEKAKSPVPKSPVEEAKSKAEVGKGEQKEE---EEKEVKEAPK 714
Query: 574 TSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSE 633
E+ EE KD +K + S + E+ V ++ S + +KET E
Sbjct: 715 EEKVEKKEEKP-----KDVPEKKKAESPVKEEAVAEVVTITKSVKVHL-----EKETKEE 764
Query: 634 APPLLFSDEEEKEAQLGVKSVDKKVESAKESLK---------FGRTDVAESEKEGLLTRS 684
PL E+EK G + + AK S K G+ +V + KE R
Sbjct: 765 GKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGRE 824
Query: 685 AQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKG 739
++ V + L S + KG D+ E+K+ ++ E G G
Sbjct: 825 EEKGVVTNGLDLSPADEKKGG-----------DKSEEKVVVTKTVEKITSEGGDG 868
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 58.2 bits (139), Expect = 5e-08
Identities = 112/520 (21%), Positives = 192/520 (36%), Gaps = 96/520 (18%)
Query: 8 SVRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKA 67
S ++ +VE P LK + K +E E K D +++EA+ + L + ++ +A
Sbjct: 57 SSKIQKPKVEAPKLKVQ-HKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEA 115
Query: 68 GNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDR 127
EE +A E+ + + P E+ EEG
Sbjct: 116 AEEKEEEPEAEEE-EVAAKKSPVKATAP-------------------EVKEEEGEK---- 151
Query: 128 GSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDI 187
+ EE +EEEE +++ A E+ + S E+E+ + + ++E E E+ E
Sbjct: 152 ----EEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAK 207
Query: 188 EENTRPKRSRPTSFADELAARIKGD----AVGRVDEEPTTLPSGEAKPRKTLKEKKERRT 243
EE ++S + +EL A K + A V + P P+ ++EK +
Sbjct: 208 EEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 267
Query: 244 PSDDEEDNLFTP-PKLTDED--------------------FSPFGSGGGLFSGGKGLFDD 282
P E+ +P PK E+ SP GKG +
Sbjct: 268 PKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKG--EQ 325
Query: 283 EDEESDLFTEAPQDRQAGASVKEESSSSKPGKK-----IPAGAVSVFLGDTDVFGAASVP 337
++EE EAP++ + KEE P KK + AV+ + T
Sbjct: 326 KEEEEKEVKEAPKEEK--VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEK 383
Query: 338 SMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGD 397
KE KP Q K G + G +++ S +K S+ + ++ G
Sbjct: 384 ETKEEGKPLQQEKEKEKAG--------GEGGSEEEG--SDKGAKGSRKEDIAVNGEVEGK 433
Query: 398 EE---------GDLFKEKAVASPEATVSQTDENKA--RAEKKVTLSSSKNLKPS------ 440
EE +EK V + +S DE K ++E+KV ++ + S
Sbjct: 434 EEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGA 493
Query: 441 ------SETKTQKGLFSDEEDSEDLFSSQSASKLKGASLL 474
S T TQK +E E L S++ K+ +++
Sbjct: 494 TKYITKSVTVTQKVEEHEETFEEKLVSTKKVEKVTSHAIV 533
Score = 39.7 bits (91), Expect = 0.018
Identities = 88/415 (21%), Positives = 156/415 (37%), Gaps = 58/415 (13%)
Query: 340 KEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEE 399
+EP+ E+ K +++G+ +++ + + K + ++E
Sbjct: 121 EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE 180
Query: 400 GDLFKEKAVASPEATVSQTD--ENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDE--ED 455
G KE+ T ++ + E +A+ EKKV + S E T++ L +D E
Sbjct: 181 GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVE-------EKSEEVATKEELVADAKVEK 233
Query: 456 SEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKA 515
E S S ++ GK P S +++ + K ++ ++ EEK
Sbjct: 234 PEKAKSPVPKSPVEEK----GKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 289
Query: 516 KASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRS--KGEPRDSGTLQSQEAKAVKK 573
K S +SK +E+ + +P S A KGE ++ + +E K K
Sbjct: 290 K-SPVSKSPV-------EEKAKSPVPKSPVEEAKSKAEVGKGEQKEE---EEKEVKEAPK 338
Query: 574 TSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSE 633
E+ EE KD +K + S + E+ V ++ S + +KET E
Sbjct: 339 EEKVEKKEEKP-----KDVPEKKKAESPVKEEAVAEVVTITKSVKVHL-----EKETKEE 388
Query: 634 APPLLFSDEEEKEAQLGVKSVDKKVESAKESLK---------FGRTDVAESEKEGLLTRS 684
PL E+EK G + + AK S K G+ +V + KE R
Sbjct: 389 GKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGRE 448
Query: 685 AQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKG 739
++ V + L S + KG D+ E+K+ ++ E G G
Sbjct: 449 EEKGVVTNGLDLSPADEKKGG-----------DKSEEKVVVTKTVEKITSEGGDG 492
>gi|217035154 RCSD domain containing 1 [Homo sapiens]
Length = 416
Score = 57.0 bits (136), Expect = 1e-07
Identities = 58/185 (31%), Positives = 82/185 (44%), Gaps = 11/185 (5%)
Query: 846 ETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEH 905
++P ++S FK K S I K+QANL +PAALLP A+ + +K ++ P S
Sbjct: 67 KSPPNASHPPKFKVKS-SPLIEKLQANLTFDPAALLPGASPKSPGLKAMVSPFHSPPST- 124
Query: 906 RRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQES 965
S G+ S P + E VSFD P + L NK R + KRRP +R RR
Sbjct: 125 PSSPGVRSRP--SEAEEVPVSFDQPPEGSHLPCYNKVRTRGSIKRRPPSRRFRR----SQ 178
Query: 966 SETEDMSVPRGPIAQWADGAISPNGHR--PQLRAASGEDSTEEALAAAAAPWEG-GPVPG 1022
S+ ++ R + +GA +G P A G + E A G P
Sbjct: 179 SDCGELGDFRAVESSQQNGAKEEDGDEVLPSKSKAPGSPLSSEGAAGEGVRTLGPAEKPP 238
Query: 1023 VDRSP 1027
+ RSP
Sbjct: 239 LRRSP 243
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 56.6 bits (135), Expect = 1e-07
Identities = 106/480 (22%), Positives = 180/480 (37%), Gaps = 67/480 (13%)
Query: 125 SDRGSIVDTEEEKEEEESDEDFAHH---SDNEQ---------NRHTTQMSDE---EEDDD 169
S GS V +EE+ E+ SD + SD+ Q +R T + D+ +EDD
Sbjct: 50 SSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDS 109
Query: 170 GCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEA 229
G D F D + +D +E + D + A + G+ + TT S E
Sbjct: 110 GDDTFGDDDSGPGP-KDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESREL 168
Query: 230 KPRKTLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDL 289
+ K E + + E ++E + GS G G DDE +SD
Sbjct: 169 DNEDRVDSKPEGGDSTQESE---------SEEHWVGGGSDGESSHGDGSELDDEGMQSD- 218
Query: 290 FTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPT 349
D ++ S + S + G K + +T G + + + P +
Sbjct: 219 ------DPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQL-----LEHPSRKI 267
Query: 350 PRKSPYG-PPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGD----LFK 404
RKS DD++ ++ S +S TG Q D GD + D L +
Sbjct: 268 FRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQ 327
Query: 405 EK--------AVASPEATVSQTDENKARAEKKVTLSSSKNLKP-SSETKTQKGLFSDEED 455
E+ + +S EA +S + + E+ V+ S N P +S + Q+ S EED
Sbjct: 328 EESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEED 387
Query: 456 SEDLFS-SQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEK 514
S S S+S S+ + A + + E++N + + ++Q EE
Sbjct: 388 SSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEES 447
Query: 515 AKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKT 574
+ S + S S +ED ++ + SK + G L++ E ++ K T
Sbjct: 448 HSEEDDSDSQDS----SRSKED-----------SNSTESKSSSEEDGQLKNIEIESRKLT 492
Score = 39.7 bits (91), Expect = 0.018
Identities = 90/407 (22%), Positives = 148/407 (36%), Gaps = 80/407 (19%)
Query: 364 DDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEE--GDLFKEKAVASPEATVSQTDEN 421
DDD+ D DD F S P + + G +E D + ++P+ S D
Sbjct: 103 DDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQD-- 160
Query: 422 KARAEKKVTLSSSKNL--KPSSETKTQKGLFSDEEDSEDLF----SSQSASKLKGASLLP 475
T S S+ L + ++K + G + E +SE+ + S +S G+ L
Sbjct: 161 --------TTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSEL-- 210
Query: 476 GKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFS---- 531
+ D+ E G + + E ++ + S LL
Sbjct: 211 ----DDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRK 266
Query: 532 -------SDEEDQWNIPASQT--HLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEE 582
S+E+D+ + + T + SDS RD+G SQ + K S +ED +
Sbjct: 267 IFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGL--SQPRRDSKGDS--QEDSK 322
Query: 583 DDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEA------PP 636
++L SQ+++Q V D S S + + + ++E VSE+ P
Sbjct: 323 ENL------SQEESQNV-----DGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPT 371
Query: 637 LLF--------SDEEEKEAQLGVKSVDKKVESA----KESLKFGR------TDVAESEKE 678
+ S EE+ L + + E A ESL F D S +E
Sbjct: 372 TSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQE 431
Query: 679 GLLTRS----AQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEED 721
GL + S +Q HS+ S S +K + + S EED
Sbjct: 432 GLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEED 478
Score = 34.7 bits (78), Expect = 0.59
Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 26/186 (13%)
Query: 69 NSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRG 128
N S+E+ + + E++ E + D P P + +QED SSEE S +
Sbjct: 345 NLSSQENSSESQEEVVSESRG---DNPDPT---TSYVEDQEDSD----SSEEDSSHTLSH 394
Query: 129 SIVDTEEEKEEEESDE--DFAHHS-DNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIE 185
S ++ EE+ + ES E +F+ S ++ ++ +++ + + ++ EED
Sbjct: 395 SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 454
Query: 186 DIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPS 245
D ++++R K D + K + EE L + E + RK + + P
Sbjct: 455 DSQDSSRSKE-------DSNSTESKSSS-----EEDGQLKNIEIESRKLTVDAYHNK-PI 501
Query: 246 DDEEDN 251
D++DN
Sbjct: 502 GDQDDN 507
Score = 32.0 bits (71), Expect = 3.8
Identities = 93/463 (20%), Positives = 166/463 (35%), Gaps = 72/463 (15%)
Query: 398 EEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEED-S 456
E+ + +K +P + ++ ++ KV+ N PS T++++GL SD+
Sbjct: 28 EDSEEWKGHLAQAPTPPLESSESSEG---SKVSSEEQANEDPSDSTQSEEGLGSDDHQYI 84
Query: 457 EDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAK 516
L S S KG D +D+ED+ T + R+E
Sbjct: 85 YRLAGGFSRSTGKGGD-------------DKDDDEDDSGDDTFGDDDSGPGPKDRQEGGN 131
Query: 517 ASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSL 576
+ S + + + +S+E + P Q A D+ S E R+ ++K S
Sbjct: 132 SRLGSDEDSDDTIQASEE----SAPQGQDS-AQDTTS--ESRELDNEDRVDSKPEGGDST 184
Query: 577 FEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPP 636
E + E+ D + S L ++ + S P S+ S
Sbjct: 185 QESESEEHWVGGGSDGESSHGDGSELDDEGMQS------DDPESIRSERGNSRMNSAGMK 238
Query: 637 LLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVA-ESEKEGLLTRSAQETVKHSDLF 695
S E ++A + +E + F ++ ++ E ++ L + E VK SD
Sbjct: 239 SKESGENSEQANTQDSGGSQLLEHPSRKI-FRKSRISEEDDRSELDDNNTMEEVK-SDST 296
Query: 696 SSSSPWDKG-TKPRTKTVLSLFDEEED-----KMEDQNIIQAPQKEVGKGRDPDAHPKST 749
+S+ D G ++PR S D +ED E+ + P E + + + S+
Sbjct: 297 ENSNSRDTGLSQPRRD---SKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS 353
Query: 750 GVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLV 809
+ +E + S + DP S D ED D S L
Sbjct: 354 ---ESQEEVVSESRGDNPDPTT-----------------SYVEDQEDSDSSEEDSSHTLS 393
Query: 810 QEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSS 852
K ++ DS + ES+ S+E PE+P+D +
Sbjct: 394 HSKSE--SREEQADS----ESSESLNFSEE----SPESPEDEN 426
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 55.8 bits (133), Expect = 2e-07
Identities = 125/599 (20%), Positives = 228/599 (38%), Gaps = 107/599 (17%)
Query: 117 SSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFAD 176
S E V +RG +++ +E EEE +E+ + E+ +EEED++ +
Sbjct: 1048 SPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEE--------EEEEDEE-----EE 1094
Query: 177 SEKEEEDIEDIEENTRPKRSRPTSFADE-----LAARIKGDAVGRVDEEPTTLPSGEAKP 231
E+EEE+ E+ +++ P+ ++P S A + + + +G R++ TT
Sbjct: 1095 EEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTT-------- 1146
Query: 232 RKTLKEKKERRTPSDDEEDNLFTPPKL--------TDEDFSPFGSGGGLFSGGKGLFDDE 283
+T+ E E D D P+L ++ P GK +E
Sbjct: 1147 -ETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEE 1205
Query: 284 DEESD--LFTEAPQDRQAGASVKEESSSSKPGKK---IPAGAVSVFLGDTDVFGAASVPS 338
+E D F A R ++ ++SS+ K G K P V+ T
Sbjct: 1206 EEGKDNHCFKNADPCRN---NMNDDSSNLKEGSKDNPEPLKCKQVWPKGT------KRGL 1256
Query: 339 MKEPQKPEQPTPRK-SPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGD 397
K Q E+ T K + Y PP T + + D+ + K + GK S + I +
Sbjct: 1257 SKWRQNKERKTGFKLNLYTPPETPM-------EPDEQVTVEEQKETSEGKT-SPSPIRIE 1308
Query: 398 EEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSE-TKTQKGLFSDEEDS 456
EE KE + EA + Q + + V+ ++S KP + K ++ +EE+
Sbjct: 1309 EE---VKE----TGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEE 1361
Query: 457 EDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAK 516
E+ ++E+E + GG +K ++Q +E+ +
Sbjct: 1362 EE---------------------------EEEEEGEEEEGGGNVEKDPDGAKSQEKEEPE 1394
Query: 517 ASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSL 576
S ++K+ SA L +EE++ + S ++ + DS ++ K
Sbjct: 1395 IS--TEKEDSARLDDHEEEEEEDEEPSH----NEDHDADDEDDSHMESAEVEKEELPRES 1448
Query: 577 FEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPP 636
F+E E+ + + Q +L + VD S P E+ E PP
Sbjct: 1449 FKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPP 1508
Query: 637 LLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLF 695
++ +K+ Q K VD + + + T +SE + QE+ + D F
Sbjct: 1509 ---GEQAQKQDQKNSKEVDTEFKEGNPA-----TMEIDSETVQAVQSLTQESSEQDDTF 1559
Score = 46.2 bits (108), Expect = 2e-04
Identities = 43/158 (27%), Positives = 67/158 (42%), Gaps = 36/158 (22%)
Query: 106 MEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEE 165
+E++ G EE + +++ ++ +EEEE DE+ +H+ D+ D +
Sbjct: 1378 VEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDH----------DAD 1427
Query: 166 EDDDGCDLFADSEKEEEDIEDIEE-----------NTRPKRSRPTSFAD---ELAA---- 207
++DD A+ EKEE E +E N +P S P D +L A
Sbjct: 1428 DEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNS 1487
Query: 208 ---RIKGD--AVGRVDEEPTTLPSGEAKPRKTLKEKKE 240
+ GD AV DEEP P GE ++ K KE
Sbjct: 1488 EPKELAGDPEAVPESDEEP---PPGEQAQKQDQKNSKE 1522
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 55.5 bits (132), Expect = 3e-07
Identities = 60/250 (24%), Positives = 89/250 (35%), Gaps = 24/250 (9%)
Query: 120 EGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDG--CDLFADS 177
EG S S EE+ EE+E DED D + ++EE D C L+ADS
Sbjct: 964 EGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADS 1023
Query: 178 EKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEE----PTTLPSGEAKPRK 233
+ E + D E ++ S +S + ++ DEE P LPS PR+
Sbjct: 1024 DGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPRE 1083
Query: 234 TLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEA 293
TP+ E + P ++ +P + G ++ + L
Sbjct: 1084 V-----PVPTPAPVE---VPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPL---R 1132
Query: 294 PQDRQAGASVKEESSSSKPGKKIP------AGAVSVFLGDTDVFGAASVPSMKEPQ-KPE 346
P + AG +P IP +V +V A P PQ K
Sbjct: 1133 PPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFP 1192
Query: 347 QPTPRKSPYG 356
P RK+P G
Sbjct: 1193 GPASRKAPRG 1202
Score = 40.8 bits (94), Expect = 0.008
Identities = 60/276 (21%), Positives = 103/276 (37%), Gaps = 41/276 (14%)
Query: 226 SGEAKPRKTLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGL--FSGGKGL---- 279
S E K + K++ D E+ L P L+ D++ G G+ F+ G GL
Sbjct: 829 SKEEKAKPFQNAAKQQAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLRGAL 888
Query: 280 ----FDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAAS 335
F + +E +EA ++++ S E P ++ AG
Sbjct: 889 RLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGE-------------PG 935
Query: 336 VPSMKEPQKPE-----QPTPRKS-------PYGPPPTGLFDDDDGDDDDDFFSAPHSKPS 383
P K P++ E Q RKS + D++ D++D+
Sbjct: 936 RPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVD 995
Query: 384 KTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSET 443
T K +D DEE D + ++ + EN + ++ + + SSS + SS +
Sbjct: 996 TTKKETEVSD-GEDEESDSSSKCSLYA-----DSDGENDSTSDSESSSSSSSSSSSSSSS 1049
Query: 444 KTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLP 479
+ S E SED + + L AS P ++P
Sbjct: 1050 SSSSSSSSSESSSEDEEEEERPAALPSASPPPREVP 1085
Score = 37.7 bits (86), Expect = 0.069
Identities = 76/376 (20%), Positives = 129/376 (34%), Gaps = 92/376 (24%)
Query: 280 FDDEDEESDLFTEAPQDRQAGASVKEESSSSKPG--------KKIPAGAVSVFLGDTDVF 331
++ ++E++ F A + +QA KE++ +PG K + F + +
Sbjct: 827 WESKEEKAKPFQNAAK-QQAKEEDKEKTKLKEPGLLSLVDWAKSGGTTGIEAFAFGSGLR 885
Query: 332 GAASVPSMKEPQK-PEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQS 390
GA +PS K +K P + + P P+ ++D+ D + + + +P
Sbjct: 886 GALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPG------- 938
Query: 391 TADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLF 450
P + + + + K L S + S E+ ++K
Sbjct: 939 ------------------TKPPKRDEERGKTQGKHRKSFALDSEGE-EASQESSSEK--- 976
Query: 451 SDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQ 510
DEED E+ DE++ED KK+T +
Sbjct: 977 -DEEDDEE----------------------------DEEDEDREEAVDTTKKETEVSDGE 1007
Query: 511 REEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKA 570
EE +S K S S E D + S + +S S S S + S E+ +
Sbjct: 1008 DEESDSSS-----KCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSS 1062
Query: 571 VKKTSLFEEDEEDDLFAIAKDSQKKTQR---VSLLFEDDVDSRGSLFGSPPTSVP----- 622
EDEE++ A S R V +V + GSP T +P
Sbjct: 1063 --------EDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEAS 1114
Query: 623 ---PATKKKETVSEAP 635
PA +E+ AP
Sbjct: 1115 PARPAGPTEESPPSAP 1130
Score = 35.8 bits (81), Expect = 0.26
Identities = 41/228 (17%), Positives = 83/228 (36%), Gaps = 38/228 (16%)
Query: 136 EKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKR 195
+ E EE+ ++ + D E + +E+E+D+ + D+ K+E ++ D E+
Sbjct: 962 DSEGEEASQESSSEKDEEDD-------EEDEEDEDREEAVDTTKKETEVSDGEDEESDSS 1014
Query: 196 SRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFTP 255
S+ + +AD + D+ + ++ S + + S ++E+ P
Sbjct: 1015 SKCSLYADSDG---ENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERP 1071
Query: 256 PKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAP-----QDRQAGASV----KEE 306
L P E + T AP +R AG+ V ++E
Sbjct: 1072 AALPSASPPP-------------------REVPVPTPAPVEVPVPERVAGSPVTPLPEQE 1112
Query: 307 SSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSP 354
+S ++P S L + P+ + ++P P P P
Sbjct: 1113 ASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPP 1160
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 54.7 bits (130), Expect = 5e-07
Identities = 155/750 (20%), Positives = 270/750 (36%), Gaps = 129/750 (17%)
Query: 17 EEPVLKAEAEK------TEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNS 70
++P LK ++K T E EQK ++P V++ +N L D+ + +
Sbjct: 24 KQPALKDTSDKNDSVSNTATEIKDEQKSGTVLPAVEQCLNRSLYRPDAVAQPVTEDEFAL 83
Query: 71 DSE----------EDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEE 120
+SE + + +E +L P + +DR L YL+ +D E +
Sbjct: 84 ESEIISKLYIPKRKIISPRSIEDVLPPVEEAVDRCL-YLLDRFAQAVTKDKFALESENIS 142
Query: 121 GSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKE 180
++R +I EK + D + + T D+ D +G L A +K
Sbjct: 143 EPYFTNRRTISQQSAEKLDAACGID--------KTENGTLFEDQNVDKEGKALPATGQKA 194
Query: 181 EEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKE 240
++ P + +D ++ R +G +D ++ S E P TL K+
Sbjct: 195 -----NVSPEQPPLFTHTVKDSDHISTRF----LGSMDSLTSSEESSERPPLSTLTLKEA 245
Query: 241 RRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAG 300
+ PP P K DD+D S++ TE + +G
Sbjct: 246 DPSSKAAMRRKDSPPPGKVSSQKQP---------AEKATSDDKDSVSNIATEIKEGPISG 296
Query: 301 ASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPT 360
SS +P +K + D + +KE Q+ +P+K
Sbjct: 297 TV----SSQKQPAEKATS--------DEKDSVSNIATEIKEGQQSGTVSPQKQ------- 337
Query: 361 GLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDE 420
+ K + +T G + G + +K S +AT +TD
Sbjct: 338 ------------SAWKVIFKKKVSLLNI-ATRITGGGKSGTVSSQKQPPS-KATSDKTDS 383
Query: 421 --NKARAEKKV----TLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLL 474
N A K T+SS K +P+ + T DEEDS +++ K ++
Sbjct: 384 ALNIATEIKDGLQCGTVSSQK--QPALKATT------DEEDSVSNIATEIKDGEKSGTVS 435
Query: 475 PGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDE 534
K P + D+ED L + + ++ K+ +S +K AL ++DE
Sbjct: 436 SQKQPALKATTDEED-------------SVLNIATEIKDGEKSETVSSQKQPALKATTDE 482
Query: 535 EDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQK 594
ED +I A++ + SGT+ S++ A+K TS DE+D I + +K
Sbjct: 483 EDSVSIIATEIK---------DGEKSGTVSSRKKPALKATS----DEKDSFSNITR--EK 527
Query: 595 KTQRVSLLFEDDVDSRGSLFGSPPTSV-------PPATKKKETVSEAPPLLFSDEEEKEA 647
K +S SV K + SE PP L + +EK++
Sbjct: 528 KDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDS 587
Query: 648 QLGVKSVDKKVESAKESLKFGRTDV-AESEKEGLLTRSAQETVKH---SDLFSSSSPWDK 703
L + K E + + + A S+KE + A ET + S P K
Sbjct: 588 LLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALK 647
Query: 704 GTKPRTKTVLSLFDEEEDKMEDQNIIQAPQ 733
T + +V ++ E +D + + Q
Sbjct: 648 ATSDKKDSVSNIPTEIKDGQQSGTVSSQKQ 677
Score = 48.5 bits (114), Expect = 4e-05
Identities = 91/412 (22%), Positives = 155/412 (37%), Gaps = 50/412 (12%)
Query: 438 KPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGG 497
K SS+ + + SD++DS +++ ++ K P + D++D N+
Sbjct: 263 KVSSQKQPAEKATSDDKDSVSNIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATE 322
Query: 498 TAAKKQTLCLQAQREEKAKASELSKKKASALLF---------SSDEEDQWNIPASQTHLA 548
+Q+ + Q++ K + KKK S L S Q P+ T
Sbjct: 323 IKEGQQSGTVSPQKQSAWKV--IFKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDK 380
Query: 549 SDS--RSKGEPRDS---GTLQSQEAKAVKKTSLFEEDEEDDLFAIA---KDSQKK---TQ 597
+DS E +D GT+ SQ+ A+K T+ DEED + IA KD +K +
Sbjct: 381 TDSALNIATEIKDGLQCGTVSSQKQPALKATT----DEEDSVSNIATEIKDGEKSGTVSS 436
Query: 598 RVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLL--FSDEEEKEAQLGVKSVD 655
+ + D S+ + T + K + S+ P L +DEE+ + + + D
Sbjct: 437 QKQPALKATTDEEDSVL-NIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKD 495
Query: 656 KKVESAKESLKFGRTDVAESEKEGL--LTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVL 713
+ S K EK+ +TR ++ + S P K T +VL
Sbjct: 496 GEKSGTVSSRKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVL 555
Query: 714 SLFDEEEDKMEDQNIIQAPQKEVGKGRDPD------AHPKSTGVFQDEELLFSHKLQKDN 767
S+ EE+D + + + + RD A K G + + SHK
Sbjct: 556 SIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYG--EKTRRVSSHKQ---- 609
Query: 768 DPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKD 819
K T E SV ++ + +D+ + + SQ K KKD
Sbjct: 610 -------PALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKD 654
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 54.3 bits (129), Expect = 7e-07
Identities = 86/383 (22%), Positives = 153/383 (39%), Gaps = 51/383 (13%)
Query: 501 KKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDS 560
KK T + +++EK + L+K++ A EE + KG ++
Sbjct: 182 KKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEK------------TKKEVKGGKQEK 229
Query: 561 GTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTS 620
+ + K V+KT +++ED A ++K Q + D+ G L +
Sbjct: 230 VKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPA 289
Query: 621 VPP--ATKKKETVSEAPPLLFSDE-EEKEAQLGVKSVDKKVES---AKESLKFGRTDVAE 674
+PP T++ + A P L E E+K+A+ V S KK E K+S K DV E
Sbjct: 290 IPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDV-E 348
Query: 675 SEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQK 734
++ G + + Q TVK + ++ K +TK + + K E + +K
Sbjct: 349 KKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKK------EK 402
Query: 735 EVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGT------KKTKLLEPSVG 788
V + P K V D+++ + K+ V + K TK +E +
Sbjct: 403 HVEPAKSP---KKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIR 459
Query: 789 SLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQG---SKEKGIWKP 845
S K+ ++++K+ + K+ V + +K PE+ + SK KP
Sbjct: 460 K----------EKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKP 509
Query: 846 ETPQDSSGLAPFKTKEPSTRIGK 868
+ PQ L K ++P +I K
Sbjct: 510 KPPQ----LQGKKEEKPEPQIKK 528
Score = 47.4 bits (111), Expect = 9e-05
Identities = 65/277 (23%), Positives = 113/277 (40%), Gaps = 39/277 (14%)
Query: 409 ASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKL 468
ASP + + + K +AEKKVT + K K + K++K D E E AS+
Sbjct: 305 ASP--ALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKE----PGKASET 358
Query: 469 KGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASAL 528
K ++ K+ + DE +ED+ K+T + K K E +K
Sbjct: 359 KQGTV---KIAAQAAAKKDEKKEDS--------KKTKKPAEVEQPKGKKQEKKEKHVEP- 406
Query: 529 LFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAI 588
+ + + ++P+ + A R+K E ++ K +KT+ E E I
Sbjct: 407 --AKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQE------I 458
Query: 589 AKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEA-------PPLLFSD 641
K+ KT + L ++ + + + P TKK E +S+A PP L
Sbjct: 459 RKEKSGKTSSI-LKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGK 517
Query: 642 EEEKEAQLGVKSVDKKVESA-KESLKFGRTDVAESEK 677
+EEK + K+ + A E ++ + D+ + EK
Sbjct: 518 KEEKPE----PQIKKEAKPAISEKVQIHKQDIVKPEK 550
Score = 46.6 bits (109), Expect = 1e-04
Identities = 120/555 (21%), Positives = 210/555 (37%), Gaps = 104/555 (18%)
Query: 364 DDDDGDDDDD----------------FFSAPHSKPSKTGKVQSTADIFGDEEG-DLFKEK 406
+DDDGD+D D + KP + K+Q+ E+G + +EK
Sbjct: 120 EDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPER--KIQTKVTHKEKEKGKEKVREK 177
Query: 407 AVASPEATVSQTDENKARAEKKVTLSSSKNLKPS--SETKTQKGLFSDEEDSEDLFSSQS 464
+AT + E K + E K K K + SE KT+K + +++ Q+
Sbjct: 178 EKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEK----VKQT 233
Query: 465 ASKLKGASLLPG-------KLPTSVSLFDDEDEE-------DNLFGGTAAKKQTLCL--- 507
A+K+K P K +VS + +D+ D G Q+ +
Sbjct: 234 AAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPP 293
Query: 508 ----QAQR--------EEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKG 555
QA R EEK + ++KK ++ ++ED +T + + + G
Sbjct: 294 LPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPG 353
Query: 556 EPRDS--GTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGSL 613
+ ++ GT++ A KK DE+ K+ KKT++ + + +G
Sbjct: 354 KASETKQGTVKIAAQAAAKK------DEK-------KEDSKKTKKPA----EVEQPKGKK 396
Query: 614 FGSPPTSVPPA--TKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTD 671
V PA KK+ +V + E KE ++G S+ K V KE K +T
Sbjct: 397 QEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKE-EIGAVSIKKAVPGKKEE-KTTKTV 454
Query: 672 VAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQA 731
E KE ++ K S + P KG + K SL ++E + +D+ + +A
Sbjct: 455 EQEIRKE--------KSGKTSSILKDKEP-IKGKE--EKVPASLKEKEPETKKDEKMSKA 503
Query: 732 PQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLF 791
GK + PK + +E +++K+ P + K +++P
Sbjct: 504 -----GK----EVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSH 554
Query: 792 GDDEDDDLFS-SAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQD 850
G E+ L A + + K K +H ++ P SI+ K K K +
Sbjct: 555 GKPEEKVLKQVKAVTIEKTAKPKPTKKAEH------REREPPSIKTDKPKPTPKGTSEVT 608
Query: 851 SSGLAPFKTKEPSTR 865
SG + E ++
Sbjct: 609 ESGKKKTEISEKESK 623
Score = 35.8 bits (81), Expect = 0.26
Identities = 78/386 (20%), Positives = 145/386 (37%), Gaps = 55/386 (14%)
Query: 14 EEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFE--QLDIK-AGNS 70
EE E KAE + T + K +E++++ + + A++ + A E Q +K A +
Sbjct: 310 EEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQA 369
Query: 71 DSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSI 130
+++D+ + +P + +++P G K +++ V + +E SV SD+
Sbjct: 370 AAKKDEKKEDSKKTKKPAE--VEQPK----GKKQEKKEKHVEPAKSPKKEHSVPSDKQVK 423
Query: 131 VDTEEEKE---------------EEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFA 175
TE KE EE++ + E++ T+ + ++E G +
Sbjct: 424 AKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKV 483
Query: 176 DS---EKEEEDIEDIEENTRPKRSRPT------SFADELAARIKGDAVGRVDEEPTTLPS 226
+ EKE E +D + + K +P ++ +IK +A + E+
Sbjct: 484 PASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQ 543
Query: 227 GEAKPRKTLK-----------------EKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSG 269
KP KT+ EK + P+ E PP + + P G
Sbjct: 544 DIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKG 603
Query: 270 -GGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDT 328
+ GK + ++ES + R+ S ++ES K A
Sbjct: 604 TSEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPA----RVSK 659
Query: 329 DVFGAASVPSMKEPQKPEQPTPRKSP 354
DV + KE + PT +KSP
Sbjct: 660 DVEDVPASKKAKEGTEDVSPTKQKSP 685
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 53.9 bits (128), Expect = 9e-07
Identities = 132/672 (19%), Positives = 250/672 (37%), Gaps = 107/672 (15%)
Query: 108 QEDVGLGELSSE-EGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEE 166
++D+ L L++E EG+ + ++ +K++E+ +DF ++ + + +
Sbjct: 14 KDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIK 73
Query: 167 DDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPS 226
D +E EE+ ++ + ++ + SF D + L
Sbjct: 74 ADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDN---------------DSEELED 118
Query: 227 GEAKPRKTLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEE 286
++K +KT K K E + SDD++D P K G S K +EDE+
Sbjct: 119 KDSKSKKTAKPKVEMYSGSDDDDDFNKLPKK---------AKGKAQKSNKKWDGSEEDED 169
Query: 287 -SDLFTEAPQDRQAGASVKE------------ESSSSKPGKKIPAGAVSVFLGDTDVFGA 333
S E + +G S E ++ +KPG I +G D D
Sbjct: 170 NSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGN-----EDDDASFK 224
Query: 334 ASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTAD 393
+ K+ +K E+ ++ ++ + +TGK +
Sbjct: 225 IKTVAQKKAEKKERERKKRD---------------EEKAKLRKLKEKEELETGKKDQSKQ 269
Query: 394 IFGDEEGDLFKEKAVASP---EATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLF 450
E F+E+ V S + V E KA ++ K + K +KG
Sbjct: 270 ---KESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAE-DDNEGDKKKKDKKKKKGEK 325
Query: 451 SDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQ 510
++E + S++ K +L K ++E+ L A +K+ L+ +
Sbjct: 326 EEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQE 385
Query: 511 REEKAKASELSK----KKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQ 566
+ E+ K E + KK LL S E +R++ E LQ+Q
Sbjct: 386 KRERKKQKEKERKERLKKEGKLLTKSQRE---------------ARARAE-ATLKLLQAQ 429
Query: 567 EAKAVKKTSL-----FEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSV 621
+ K SL ED++ +S++ ++ + L +V +G +
Sbjct: 430 GVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQG--VPEKEETP 487
Query: 622 PPATKKKETVSEAPPL-----LFSDEEEKEAQ-----LGVKSVDKKVESAKESLKFGRTD 671
PP ++E +E L + SDEE ++ + + VK ++ E +E +
Sbjct: 488 PPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEES 547
Query: 672 VAESEKEGLLTRSA--QETVKHSDLFSSSSPWDKGTKP-RTKTVLSLFDEEEDKMEDQNI 728
E E+EG S +E K SD S DK KP + + S +D ++D+ +++
Sbjct: 548 EEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDK--KPSKEMSSDSEYDSDDDRTKEERA 605
Query: 729 IQAPQKEVGKGR 740
++ + K R
Sbjct: 606 YDKAKRRIEKRR 617
Score = 40.4 bits (93), Expect = 0.011
Identities = 76/436 (17%), Positives = 175/436 (40%), Gaps = 57/436 (13%)
Query: 20 VLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANG 79
V + +AEK E+E+ + +E + K++E ++ +Q K EE+
Sbjct: 228 VAQKKAEKKERERKKRDEEKAKLRKLKEKE----ELETGKKDQSKQKESQRKFEEETVKS 283
Query: 80 RVEL---ILEPKDLYIDRPLPYLIGSKLFMEQED----VGLGELSSEEGSVGSDRGSIVD 132
+V + ++ + + P ++ +++D G E +E G + ++
Sbjct: 284 KVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKA 343
Query: 133 TEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTR 192
+E + + +E+ + E+ + ++ + ++++ + ++E + ++ E R
Sbjct: 344 MQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLE---QEKRERKKQKEKERKER 400
Query: 193 PKRSRPTSFADELAARIKGDAVGR-VDEEPTTLPSGEAKPRK--TLKEKKERRTPSDDEE 249
K+ + AR + +A + + + +PS ++ P+K ++KK ++ P E
Sbjct: 401 LKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLES 460
Query: 250 DNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQ-AGASVKEESS 308
+ +L + +G+ + E+ + E +D + AG E +
Sbjct: 461 KEVSESMELC----------AAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMA 510
Query: 309 SSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDG 368
S + +K+ V + + + P +E ++ E+ +S G + +G
Sbjct: 511 SDEETEKVEGNKVHIEVKEN--------PEEEEEEEEEEEEDEESEEEEEEEGESEGSEG 562
Query: 369 DDDDDFFS-------APHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDEN 421
D++D+ S KPSK + ++D D + D KE+ D+
Sbjct: 563 DEEDEKVSDEKDSGKTLDKKPSK----EMSSDSEYDSDDDRTKEERA---------YDKA 609
Query: 422 KARAEKKVTLSSSKNL 437
K R EK+ L SKN+
Sbjct: 610 KRRIEKR-RLEHSKNV 624
Score = 38.9 bits (89), Expect = 0.031
Identities = 45/222 (20%), Positives = 94/222 (42%), Gaps = 45/222 (20%)
Query: 10 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 69
R +E +E+ + + +K ++ K R +KE L+ K Q + + ++ +
Sbjct: 376 RKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPS 435
Query: 70 SDS-------EEDDANGRVELILEPKDLYIDRPL-----------------PYLIGSKLF 105
DS ED ++ LE K++ L P + +
Sbjct: 436 KDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEE 495
Query: 106 MEQEDVGLGE---LSSEEGSVGSDRGSI-----VDTEEEKEEEESDEDFAHHSDNEQNRH 157
+ ED GL + ++S+E + + + + EEE+EEEE +E+ D E
Sbjct: 496 EDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEE-----DEE---- 546
Query: 158 TTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPT 199
S+EEE+++G ++ ++E+E + D +++ + +P+
Sbjct: 547 ----SEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPS 584
Score = 36.6 bits (83), Expect = 0.15
Identities = 63/286 (22%), Positives = 108/286 (37%), Gaps = 46/286 (16%)
Query: 642 EEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLL----TRSAQETVKHSDLFSS 697
E+E + G K +KK + E + E +G+ T + + T + + F+S
Sbjct: 34 EQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTS 93
Query: 698 SSPWDKGTKPRTKTVLSLFDEE-EDKMEDQNIIQAPQKEVGKGRDPD------------- 743
KG K + ++ EE EDK P+ E+ G D D
Sbjct: 94 KDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGK 153
Query: 744 ---AHPKSTGVFQDEE----------LLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSL 790
++ K G +DE+ + S + ++D + G KK + +P
Sbjct: 154 AQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIE 213
Query: 791 FGDDEDDDLFS-SAKSQPLVQEKKRVVKK-DHSVDSFKNQKHPESIQGSKEKGIWKPETP 848
G+++DD F +Q ++K+R KK D + K E ++ K K ++
Sbjct: 214 SGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGK-----KDQSK 268
Query: 849 QDSSGLAPFKTKEPSTRIGKIQANLAINPA----ALLPTAASQISE 890
Q S + E T K+ + + PA A PTAA +E
Sbjct: 269 QKESQ----RKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNE 310
Score = 34.3 bits (77), Expect = 0.77
Identities = 51/230 (22%), Positives = 80/230 (34%), Gaps = 30/230 (13%)
Query: 649 LGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPR 708
+G K +K +S K+ + D +E EG QE K KG K +
Sbjct: 1 MGKKQKNKSEDSTKDDIDL---DALAAEIEGAGAAKEQEPQK-----------SKGKKKK 46
Query: 709 TKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQK--- 765
K +E+D +++ + + + R+ A + +EE K +K
Sbjct: 47 EKKKQDF--DEDDILKELEELSLEAQGIKADRETVAVKPTEN--NEEEFTSKDKKKKGQK 102
Query: 766 -------DNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEK--KRVV 816
DND + +K K +P V G D+DDD K +K K+
Sbjct: 103 GKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWD 162
Query: 817 KKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRI 866
+ D+ K K I S E G E Q G + +P I
Sbjct: 163 GSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNI 212
Score = 33.9 bits (76), Expect = 1.0
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Query: 1088 GEASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQKVKKNETKS--NSQQDVILTTQD 1145
G A + K K KK F DEDD+ + + E + ++ V + +
Sbjct: 30 GAAKEQEPQKSKGKKKKEKKKQDF----DEDDILKELEELSLEAQGIKADRETVAVKPTE 85
Query: 1146 IFEDDIFATEAIKPSQKTREKEKTLESNLFDDN-IDIFADLTVKPKEKSKKKVEAKSIFD 1204
E++ + + K QK +++ FDDN + D K K+ +K KVE S D
Sbjct: 86 NNEEEFTSKDKKKKGQKGKKQS-------FDDNDSEELEDKDSKSKKTAKPKVEMYSGSD 138
Query: 1205 DDMDDIFSSGIQAKTTKPKS 1224
DD DD +AK KS
Sbjct: 139 DD-DDFNKLPKKAKGKAQKS 157
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 52.8 bits (125), Expect = 2e-06
Identities = 221/1144 (19%), Positives = 413/1144 (36%), Gaps = 190/1144 (16%)
Query: 43 PKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGS 102
P+V++AV+ L L+ E G+ ++ DD LI + P P G
Sbjct: 149 PQVEKAVHEFLATLNHKEE------GSGNTAPDDEKPDTSLITQGV------PTP---GP 193
Query: 103 KLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHH----SDNEQNRHT 158
+ + + + E + S + +T K E + + + ++ R +
Sbjct: 194 SANVANDAMSILETITSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTS 253
Query: 159 TQMSDEEED--DDGCDLFADSEKEEE------DIEDIEENTRPKRSRPTSFAD--ELAAR 208
M+D+E+ D G + + K EE +E+I+ T+ + D + ++
Sbjct: 254 EDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSE 313
Query: 209 IKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGS 268
K + + +++P + GE K KEKKE+ D K+ DE
Sbjct: 314 QKNKSTDKGEKKPDSNEKGERK-----KEKKEKTEKKFDHSKKSEDTQKVKDEK------ 362
Query: 269 GGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDT 328
+A + + E +S+K K + L D+
Sbjct: 363 -----------------------QAKEKEVESLKLPSEKNSNK-AKTVEGTKEDFSLIDS 398
Query: 329 DVFGAASVP----------SMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAP 378
DV G + S +E + E T G DD + + +
Sbjct: 399 DVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGE-----ITSDDEEKNKQNKTKT 453
Query: 379 HSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLK 438
+ S GK +S + + K + + E TV Q ++ A+ +++ L N +
Sbjct: 454 QTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINRE 513
Query: 439 PSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGT 498
E + QK +SK KG +SV L +E +L
Sbjct: 514 KLEEKRKQKA------------EKTKSSKTKGQGR------SSVDL--EESSTKSLEPKA 553
Query: 499 AAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPR 558
A K+ L + E+K S+ KK + + +S ++ Q+ + +T S+ K +
Sbjct: 554 ARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKIS 613
Query: 559 DSGTLQSQEAKAVKKT-------SLFEEDEEDDLFAIAKDSQKKTQRVSLL--FEDDVDS 609
S L+ AK+ SL DE + + ++ +++T ++ +++ D+
Sbjct: 614 SSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDT 673
Query: 610 RGSLFGSPPTSV--PPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKF 667
R + + K+K T+ L D E + +K K+V+S+KE +
Sbjct: 674 RDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLK---KEVKSSKEKPER 730
Query: 668 GRT------DVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEED 721
+T V K + ++ ET HS + K +T LS D+ E
Sbjct: 731 EKTPSEDKLSVKHKYKGDCMHKTGDETELHSSE-KGLKVEENIQKQSQQTKLSSDDKTER 789
Query: 722 KMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTK 781
K + +N + +GK D P S + + +E ++K+N+ + +KTK
Sbjct: 790 KSKHRN--ERKLSVLGK----DGKPVSEYIIKTDE-----NVRKENNKK-ERRLSAEKTK 837
Query: 782 LLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKH--PESIQGSKE 839
S S + D L S L + + + +DS + PE + ++
Sbjct: 838 AEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEK 897
Query: 840 KGIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELA 899
+ + ++ + + K+K ++ ++ L A Q + KP +
Sbjct: 898 R---RTKSLLEEKLVLKSKSKTQGKQVKVVETELQEG-------ATKQATTPKPDKEKNT 947
Query: 900 FPS-SEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAAR 958
+ SE +R +E P E GV L + + HS K RA
Sbjct: 948 EENDSEKQRKSKVEDKPF----EETGVEPVLETASSSAHSTQKDS---------SHRAKL 994
Query: 959 RLAAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGG 1018
LA ++ +D + R + +S +GH+ + S +D ++ +
Sbjct: 995 PLAKEKYKSDKDSTSTR------LERKLS-DGHKSRSLKHSSKDIKKK---------DEN 1038
Query: 1019 PVPGVDRSPFAKSLGHSRGEADLFD---SGDIFSTGTGSQSVERTKPKAKIAENPANPPV 1075
D S +RG + L + S + GS S E K + K+A N + P
Sbjct: 1039 KSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPS 1098
Query: 1076 GGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQKVKKNETKSNS 1135
G + P + S D L +P + ++ P +E ++F K + N +NS
Sbjct: 1099 GSSLQRP------KKSGDMTLIPEQEP---MEIDSEPGVE---NVFEVSKTQDNR-NNNS 1145
Query: 1136 QQDV 1139
QQD+
Sbjct: 1146 QQDI 1149
Score = 41.6 bits (96), Expect = 0.005
Identities = 45/237 (18%), Positives = 96/237 (40%), Gaps = 19/237 (8%)
Query: 11 VYDEEVEEPVLKAEAEKTEQEKTREQKEVDL--IPKVQEAVNYGLQVLDSAFEQLDIKAG 68
V D +E + + +TE T+E+ DL +PK N + ++
Sbjct: 2790 VLDSRIE--TAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSET 2847
Query: 69 NSDSEEDDANGRVELILEPKDLYIDR----PLPYLIGSKLFMEQEDVGLGELSSEEGSVG 124
+ E + + ++ E + + I R P Y + + L M+ + + + E S
Sbjct: 2848 TGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPS 2907
Query: 125 SDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDI 184
S + ++ T+E +E + ++ + +D+ + + T + K +
Sbjct: 2908 SSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGR----------KPKRSLTV 2957
Query: 185 EDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKER 241
D E++ P+R R S +D + + + ++ +EE PSG A R T + + +R
Sbjct: 2958 SDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSG-ATTRSTTRSEAQR 3013
Score = 38.5 bits (88), Expect = 0.041
Identities = 92/508 (18%), Positives = 176/508 (34%), Gaps = 51/508 (10%)
Query: 386 GKVQSTADIFGDEEGDLFK---EKAVASPE---ATVSQTDENKARAEKKVTLSSSKNLKP 439
G+ +ST + EE ++ +K SPE A S T A + +S +L+
Sbjct: 2448 GQKESTLHLINAEEKNVLLNSLQKEDKSPETGTAGGSSTASYSAGRGLEGNANSPAHLRG 2507
Query: 440 SSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLF---DDEDEEDNLFG 496
+T Q D S ++ + +K + P + + F + + EDNL
Sbjct: 2508 PEQTSGQTA--KDPSVSIRYLAAVNTGAIKADDMPPVQGTVAEHSFLPAEQQGSEDNLKT 2565
Query: 497 GTAAKKQTLCLQAQREEKAKASE-----------LSKKKASALLFSSDEEDQWNIPASQT 545
T T C+ Q + A + L+ K L +D +W AS
Sbjct: 2566 ST-----TKCITGQESKIAPSHTMIPPATYSVALLAPKCEQDLTIKNDYSGKWTDQASAE 2620
Query: 546 HLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFED 605
D+ ++ + G + + + +EE L + K ++
Sbjct: 2621 KTGDDNSTRKSFPEEGDIMVTVSSEENVCDI--GNEESPLNVLGGLKLKANLKMEAYVPS 2678
Query: 606 DVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESL 665
+ + G + +PP S+ + PLL ++ L V++ + S
Sbjct: 2679 EEEKNGEIL-APPESLCGGKPSGIAELQREPLLVNES------LNVENSGFRTNEEIHSE 2731
Query: 666 KFGRTDVAESEK---EGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDK 722
+ + +++ K E + S + K + P K R + LS DE +D
Sbjct: 2732 SYNKGEISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRK----RKQHYLSSEDEPDDN 2787
Query: 723 MEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKL 782
+ + + E + + P+ P T +L K + + K
Sbjct: 2788 PD----VLDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYS 2843
Query: 783 LEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGI 842
+ G ++DD + S + QP++ ++KR + + V++ K + GI
Sbjct: 2844 SSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKD----DSKTDTGI 2899
Query: 843 WKPETPQDSSGLAPFKTKEPSTRIGKIQ 870
E SS L +T E + +Q
Sbjct: 2900 VTVEQSPSSSKLKVMQTDESNKETANLQ 2927
Score = 36.6 bits (83), Expect = 0.15
Identities = 118/634 (18%), Positives = 232/634 (36%), Gaps = 105/634 (16%)
Query: 10 RVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGN 69
R + E E K +AEKT+ KT+ Q +D++ +
Sbjct: 508 RQINREKLEEKRKQKAEKTKSSKTKGQGR----------------------SSVDLEESS 545
Query: 70 SDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGS 129
+ S E A R++ +L+ + + L + +++ + E S ++ D
Sbjct: 546 TKSLEPKA-ARIKEVLKER-----KVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKE 599
Query: 130 IVDTEE--EKEEEESDEDFAH-HSDNE----------------QNRHTTQMSDEEEDDDG 170
+ T E EKE+ S ++ H H+ +E +N++ +++ E +
Sbjct: 600 TLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTS 659
Query: 171 CDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDA-VGRVDEEPTTLPSGEA 229
+ + +EE D D++ + T + + +K + + + D E L S
Sbjct: 660 TPVIMEGVQEETDTRDVKRQVE-RSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLK 718
Query: 230 KPRKTLKEKKER-RTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESD 288
K K+ KEK ER +TPS ED L K + G L S KGL E +
Sbjct: 719 KEVKSSKEKPEREKTPS---EDKLSVKHKYKGDCMHKTGDETELHSSEKGL----KVEEN 771
Query: 289 LFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQP 348
+ ++ Q + + E S + +K+ V G P + K ++
Sbjct: 772 IQKQSQQTKLSSDDKTERKSKHRNERKL------------SVLGKDGKPVSEYIIKTDEN 819
Query: 349 TPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAV 408
+ + + + SA +K + S + I D G
Sbjct: 820 VRK---------------ENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLG-------- 856
Query: 409 ASPEATVSQTDENKARAEKKVTLSSS---KNLKPSSETKTQKGLFSDEEDSEDLFSSQSA 465
S + ++ +++ +E K + S+ NLKP +K + + + S+S
Sbjct: 857 -SKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSK 915
Query: 466 SKLKGASLLPGKL---PTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQR-EEKAKASELS 521
++ K ++ +L T + D+E N + K++ ++ + EE L
Sbjct: 916 TQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLE 975
Query: 522 KKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTS----LF 577
+SA D + +P ++ SD S + +++++K +S
Sbjct: 976 TASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKK 1035
Query: 578 EEDEEDDLFAIAKD-SQKKTQRVSLLFEDDVDSR 610
+E++ DD D S +K + S L E + R
Sbjct: 1036 DENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRR 1069
Score = 33.5 bits (75), Expect = 1.3
Identities = 47/231 (20%), Positives = 93/231 (40%), Gaps = 19/231 (8%)
Query: 512 EEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAV 571
EE+ + K+K L + +D ++ S+ A + EP D+ S++ + +
Sbjct: 2762 EEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEEL 2821
Query: 572 KKTSLFEED------EEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPAT 625
KTS EE D ++ ++ + +K + ++D D+ S P +
Sbjct: 2822 PKTSSETNSTTSRVMEEKDEYSSSETTGEKPE------QNDDDTIKSQEEDQPIIIKRKR 2875
Query: 626 KKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSA 685
+ L D+ + + G+ +V++ S+K LK +TD + E L RS
Sbjct: 2876 GRPRKYPVETTLKMKDDSKTDT--GIVTVEQSPSSSK--LKVMQTDESNKETANLQERSI 2931
Query: 686 QETVKHSDLFSSSSPWDKGTKP-RTKTVLSLFDEEEDKMEDQNIIQAPQKE 735
+ +S +G KP R+ TV + E + + Q + P ++
Sbjct: 2932 SNDDGEEKIVTSVR--RRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVED 2980
Score = 31.6 bits (70), Expect = 5.0
Identities = 17/64 (26%), Positives = 31/64 (48%)
Query: 129 SIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIE 188
S+ D E+K+E+ESDE+ ++E + TT+ + E + S K + ++
Sbjct: 2973 SVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQRSKTQLSPSIKRKREVSPPG 3032
Query: 189 ENTR 192
TR
Sbjct: 3033 ARTR 3036
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 52.8 bits (125), Expect = 2e-06
Identities = 104/512 (20%), Positives = 189/512 (36%), Gaps = 71/512 (13%)
Query: 20 VLKAEAEKTEQEKTREQKEVDLI----PKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEED 75
+L+A+A EK+ ++ + + PK QE + L+ + +IK + ++
Sbjct: 1419 ILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDT 1478
Query: 76 DANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEE 135
+ I KD + + + + E S E S R
Sbjct: 1479 FKKDSQQDIPSSKD---HKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGS 1535
Query: 136 EKEEEESDEDFAHHSDNEQ--NRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRP 193
+E ED + E + +MS +ED G + D E +++I +T
Sbjct: 1536 SSSDEYKQEDSQGSGEEEDFIRKQIIEMS-ADEDASGSE---DDEFIRNQLKEISSSTES 1591
Query: 194 KRSRPTSFADELAA----RIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKE---RRTPSD 246
++ T ++ A R+ + +DE+ S + + E E R T S
Sbjct: 1592 QKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQ 1651
Query: 247 DEEDNLFTPPK-----LTDEDFSPFGSGGGLFSGGKGL---FDDEDE-ESDLFTEAPQDR 297
+ E+ + T T E S S K FD+E E E + T++P+DR
Sbjct: 1652 ESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDR 1711
Query: 298 QAG-ASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYG 356
G S +SS PG +VS D+D S PS K+ + +Q R P+G
Sbjct: 1712 SRGEGSSSLHASSFTPGTS--PTSVSSLDEDSD-----SSPSHKKGESKQQRKARHRPHG 1764
Query: 357 PPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVS 416
P + D + ++ ++ ++ ++E E+ + S
Sbjct: 1765 PLLPTIEDSSEEEE-----------------LREEEELLKEQEKQREIEQQQRKSSSKKS 1807
Query: 417 QTDENKARAEKK--------VTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKL 468
+ D+++ RA+++ LS ++ P+ E + + S +S S
Sbjct: 1808 KKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDP 1867
Query: 469 KGASLLPGK---------LPTSVSLFDDEDEE 491
+G + P K LPT+VSL+ DE+
Sbjct: 1868 EGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQ 1899
Score = 47.4 bits (111), Expect = 9e-05
Identities = 175/866 (20%), Positives = 307/866 (35%), Gaps = 199/866 (22%)
Query: 17 EEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDD 76
+E +K EAEK EK +E ++ IP + D K S E+D
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTT---------------DQKQEESKLEKDK 1204
Query: 77 ANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEE 136
A+ E +PLP KL E+E ++ SEE + +++ ++
Sbjct: 1205 ASALQE----------KKPLPE--EKKLIPEEE-----KIRSEE------KKPLLEEKKP 1241
Query: 137 KEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRS 196
E++ A S E+ +H DL + E E +E PK
Sbjct: 1242 TPEDKKLLPEAKTSAPEEQKH--------------DLLKSQVQIAE--EKLEGRVAPKTV 1285
Query: 197 RPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFTPP 256
+ + +++G G P +LP + K KT+KE+ + PP
Sbjct: 1286 QE---GKQPQTKMEGLPSGT----PQSLPKEDDKTTKTIKEQPQ--------------PP 1324
Query: 257 KLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKI 316
D GK + ED++SD T + Q ++ + + SS
Sbjct: 1325 CTAKPD---------QVEPGKEKTEKEDDKSD--TSSSQQPKSPQGLSDTGYSSD----- 1368
Query: 317 PAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFS 376
+S LG+ +PS+ PT K GL D + S
Sbjct: 1369 ---GISSSLGE--------IPSLI-------PTDEKDIL----KGLKKDSFSQE-----S 1401
Query: 377 APHSKPSKTGKVQST--------ADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKK 428
+P S PS K++ST A DE+ + + SPE Q EK
Sbjct: 1402 SP-SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQ--------EKT 1452
Query: 429 VTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDE 488
+LS + + S E + +E+ +D F S + + D +
Sbjct: 1453 QSLSETLEITISEEE-----IKESQEERKDTFKKDSQQDIPSSK-------------DHK 1494
Query: 489 DEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLA 548
++ + + T ++ ++ E + K++ S SSDE Q
Sbjct: 1495 EKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ----------- 1543
Query: 549 SDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDE--EDDLFAIAK--DSQKKTQRVSLLFE 604
DS+ GE D Q E A + S E+DE + L I+ +SQKK
Sbjct: 1544 EDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKK--------- 1594
Query: 605 DDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKES 664
++ +G + + T+K T S +E+ + D +
Sbjct: 1595 EETKGKGKITAGKHRRL---TRKSST---------SIDEDAGRRHSWHDEDDEAFDESPE 1642
Query: 665 LKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKME 724
LK+ T ESE+ + K +L S+ + DK + ++ SL+ +EE ++E
Sbjct: 1643 LKYRETKSQESEELVVTGGGGLRRFKTIELNSTIA--DKYSAESSQKKTSLYFDEEPELE 1700
Query: 725 DQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLE 784
+++ +P+ H S + S D+ P ++ K
Sbjct: 1701 MESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARH 1760
Query: 785 PSVGSLFGDDEDDDLFSSAKSQPLV---QEKKR-VVKKDHSVDSFKNQKHPESIQGSKEK 840
G L ED + + + QEK+R + ++ S K++K + ++ + +
Sbjct: 1761 RPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRR 1820
Query: 841 GIWKPETPQDSSGLAPFKTKEPSTRI 866
+P+TP S L+P + P+ +
Sbjct: 1821 E--RPKTP--PSNLSPIEDASPTEEL 1842
Score = 44.7 bits (104), Expect = 6e-04
Identities = 138/658 (20%), Positives = 252/658 (38%), Gaps = 116/658 (17%)
Query: 626 KKKETVS--EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTR 683
K KET+S + PP++ +D++++E++L E K+ L + + E EK R
Sbjct: 1175 KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQE--KKPLPEEKKLIPEEEK----IR 1228
Query: 684 SAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPD 743
S ++ + +P DK P KT S +E++ + + A +K G+
Sbjct: 1229 SEEKKPLLEE--KKPTPEDKKLLPEAKT--SAPEEQKHDLLKSQVQIAEEKLEGR----- 1279
Query: 744 AHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSA 803
PK+ +Q+ P TK L + SL EDD +
Sbjct: 1280 VAPKT--------------VQEGKQPQ------TKMEGLPSGTPQSL--PKEDDKTTKTI 1317
Query: 804 KSQP----------LVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSG 853
K QP + K++ K+D D+ +Q+ P+S QG + G + + S G
Sbjct: 1318 KEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQ-PKSPQGLSDTG-YSSDGISSSLG 1375
Query: 854 ----LAPFKTKEPSTRIGK---IQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHR 906
L P K+ + K Q + +P+ L ++ +S ++ LA SE +
Sbjct: 1376 EIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSE-K 1434
Query: 907 RSHGLESVPVLPGSGEAGVSF----DLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAA 962
++ E P P E S ++ + + + + R K Q + +
Sbjct: 1435 KTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHK 1494
Query: 963 QESSETEDMSVPRGPIAQWADGAISPNGHRPQL--RAASGEDSTEEALAAAAAPWEGGPV 1020
++S +D++ R P + + S N PQ R + G S++E E
Sbjct: 1495 EKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ------EDSQG 1548
Query: 1021 PGVDRSPFAKSLGHSRGEADLFDSGDI---------FSTGTGSQSVERTKPKAKIAENPA 1071
G + K + + D S D S+ T SQ E TK K KI
Sbjct: 1549 SGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAG-- 1606
Query: 1072 NPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQ--KVKKN 1129
K S D+D A + +++ DEDD D+ ++K
Sbjct: 1607 --------KHRRLTRKSSTSIDED---------AGRRHSW---HDEDDEAFDESPELKYR 1646
Query: 1130 ETKSNSQQDVILT----TQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDI-FAD 1184
ETKS +++++T + ++ +T A K S ++ +K+ +L FD+ ++
Sbjct: 1647 ETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSL---YFDEEPELEMES 1703
Query: 1185 LTVKPKEKSK----KKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHK 1238
LT P+++S+ + A S SS + + P + ++ + + H+
Sbjct: 1704 LTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHR 1761
Score = 33.5 bits (75), Expect = 1.3
Identities = 58/282 (20%), Positives = 105/282 (37%), Gaps = 31/282 (10%)
Query: 333 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 392
AA + + K P+ S + P + D + D+ S S S G + S A
Sbjct: 4181 AAILYQKQSKHKKSLIDPKMSKFSPI------QESRDLEPDYSSYMTSSTSSIGGISSRA 4234
Query: 393 DIFGDE----------EGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSE 442
+ D+ + F ++ + T+ T + + E SS +PSS
Sbjct: 4235 RLLQDDITFGLRKNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSR 4294
Query: 443 TKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKK 502
+ GL D D SS S+ +LK + S + + +L + +
Sbjct: 4295 PSSVYGL--DLSIKRD--SSSSSLRLKAQEAEALDVSFSHASSSARTKPTSLPISQSRGR 4350
Query: 503 QTLCLQAQREEK-----AKASELSKKKASALL-FSSDEEDQW----NIPASQTHLASDSR 552
+ Q EE + +++ A L S+D DQ+ ++P Q H+ +SR
Sbjct: 4351 IPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREESR 4410
Query: 553 SKGEPRDSGTLQSQEAKAVKKTSLFE-EDEEDDLFAIAKDSQ 593
++G RD + A+ + + EE D F ++S+
Sbjct: 4411 TRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPRESR 4452
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 52.8 bits (125), Expect = 2e-06
Identities = 104/512 (20%), Positives = 189/512 (36%), Gaps = 71/512 (13%)
Query: 20 VLKAEAEKTEQEKTREQKEVDLI----PKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEED 75
+L+A+A EK+ ++ + + PK QE + L+ + +IK + ++
Sbjct: 1419 ILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDT 1478
Query: 76 DANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEE 135
+ I KD + + + + E S E S R
Sbjct: 1479 FKKDSQQDIPSSKD---HKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGS 1535
Query: 136 EKEEEESDEDFAHHSDNEQ--NRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRP 193
+E ED + E + +MS +ED G + D E +++I +T
Sbjct: 1536 SSSDEYKQEDSQGSGEEEDFIRKQIIEMS-ADEDASGSE---DDEFIRNQLKEISSSTES 1591
Query: 194 KRSRPTSFADELAA----RIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKE---RRTPSD 246
++ T ++ A R+ + +DE+ S + + E E R T S
Sbjct: 1592 QKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQ 1651
Query: 247 DEEDNLFTPPK-----LTDEDFSPFGSGGGLFSGGKGL---FDDEDE-ESDLFTEAPQDR 297
+ E+ + T T E S S K FD+E E E + T++P+DR
Sbjct: 1652 ESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDR 1711
Query: 298 QAG-ASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYG 356
G S +SS PG +VS D+D S PS K+ + +Q R P+G
Sbjct: 1712 SRGEGSSSLHASSFTPGTS--PTSVSSLDEDSD-----SSPSHKKGESKQQRKARHRPHG 1764
Query: 357 PPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVS 416
P + D + ++ ++ ++ ++E E+ + S
Sbjct: 1765 PLLPTIEDSSEEEE-----------------LREEEELLKEQEKQREIEQQQRKSSSKKS 1807
Query: 417 QTDENKARAEKK--------VTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKL 468
+ D+++ RA+++ LS ++ P+ E + + S +S S
Sbjct: 1808 KKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDP 1867
Query: 469 KGASLLPGK---------LPTSVSLFDDEDEE 491
+G + P K LPT+VSL+ DE+
Sbjct: 1868 EGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQ 1899
Score = 47.4 bits (111), Expect = 9e-05
Identities = 175/866 (20%), Positives = 307/866 (35%), Gaps = 199/866 (22%)
Query: 17 EEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDD 76
+E +K EAEK EK +E ++ IP + D K S E+D
Sbjct: 1160 QEQEVKTEAEKVILEKVKETLSMEKIPPMVTT---------------DQKQEESKLEKDK 1204
Query: 77 ANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEE 136
A+ E +PLP KL E+E ++ SEE + +++ ++
Sbjct: 1205 ASALQE----------KKPLPE--EKKLIPEEE-----KIRSEE------KKPLLEEKKP 1241
Query: 137 KEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRS 196
E++ A S E+ +H DL + E E +E PK
Sbjct: 1242 TPEDKKLLPEAKTSAPEEQKH--------------DLLKSQVQIAE--EKLEGRVAPKTV 1285
Query: 197 RPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFTPP 256
+ + +++G G P +LP + K KT+KE+ + PP
Sbjct: 1286 QE---GKQPQTKMEGLPSGT----PQSLPKEDDKTTKTIKEQPQ--------------PP 1324
Query: 257 KLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKI 316
D GK + ED++SD T + Q ++ + + SS
Sbjct: 1325 CTAKPD---------QVEPGKEKTEKEDDKSD--TSSSQQPKSPQGLSDTGYSSD----- 1368
Query: 317 PAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFS 376
+S LG+ +PS+ PT K GL D + S
Sbjct: 1369 ---GISSSLGE--------IPSLI-------PTDEKDIL----KGLKKDSFSQE-----S 1401
Query: 377 APHSKPSKTGKVQST--------ADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKK 428
+P S PS K++ST A DE+ + + SPE Q EK
Sbjct: 1402 SP-SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQ--------EKT 1452
Query: 429 VTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDE 488
+LS + + S E + +E+ +D F S + + D +
Sbjct: 1453 QSLSETLEITISEEE-----IKESQEERKDTFKKDSQQDIPSSK-------------DHK 1494
Query: 489 DEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLA 548
++ + + T ++ ++ E + K++ S SSDE Q
Sbjct: 1495 EKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ----------- 1543
Query: 549 SDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDE--EDDLFAIAK--DSQKKTQRVSLLFE 604
DS+ GE D Q E A + S E+DE + L I+ +SQKK
Sbjct: 1544 EDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKK--------- 1594
Query: 605 DDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKES 664
++ +G + + T+K T S +E+ + D +
Sbjct: 1595 EETKGKGKITAGKHRRL---TRKSST---------SIDEDAGRRHSWHDEDDEAFDESPE 1642
Query: 665 LKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKME 724
LK+ T ESE+ + K +L S+ + DK + ++ SL+ +EE ++E
Sbjct: 1643 LKYRETKSQESEELVVTGGGGLRRFKTIELNSTIA--DKYSAESSQKKTSLYFDEEPELE 1700
Query: 725 DQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLE 784
+++ +P+ H S + S D+ P ++ K
Sbjct: 1701 MESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARH 1760
Query: 785 PSVGSLFGDDEDDDLFSSAKSQPLV---QEKKR-VVKKDHSVDSFKNQKHPESIQGSKEK 840
G L ED + + + QEK+R + ++ S K++K + ++ + +
Sbjct: 1761 RPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRR 1820
Query: 841 GIWKPETPQDSSGLAPFKTKEPSTRI 866
+P+TP S L+P + P+ +
Sbjct: 1821 E--RPKTP--PSNLSPIEDASPTEEL 1842
Score = 44.7 bits (104), Expect = 6e-04
Identities = 138/658 (20%), Positives = 252/658 (38%), Gaps = 116/658 (17%)
Query: 626 KKKETVS--EAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTR 683
K KET+S + PP++ +D++++E++L E K+ L + + E EK R
Sbjct: 1175 KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQE--KKPLPEEKKLIPEEEK----IR 1228
Query: 684 SAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPD 743
S ++ + +P DK P KT S +E++ + + A +K G+
Sbjct: 1229 SEEKKPLLEE--KKPTPEDKKLLPEAKT--SAPEEQKHDLLKSQVQIAEEKLEGR----- 1279
Query: 744 AHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSA 803
PK+ +Q+ P TK L + SL EDD +
Sbjct: 1280 VAPKT--------------VQEGKQPQ------TKMEGLPSGTPQSL--PKEDDKTTKTI 1317
Query: 804 KSQP----------LVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSG 853
K QP + K++ K+D D+ +Q+ P+S QG + G + + S G
Sbjct: 1318 KEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQ-PKSPQGLSDTG-YSSDGISSSLG 1375
Query: 854 ----LAPFKTKEPSTRIGK---IQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHR 906
L P K+ + K Q + +P+ L ++ +S ++ LA SE +
Sbjct: 1376 EIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSE-K 1434
Query: 907 RSHGLESVPVLPGSGEAGVSF----DLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAA 962
++ E P P E S ++ + + + + R K Q + +
Sbjct: 1435 KTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHK 1494
Query: 963 QESSETEDMSVPRGPIAQWADGAISPNGHRPQL--RAASGEDSTEEALAAAAAPWEGGPV 1020
++S +D++ R P + + S N PQ R + G S++E E
Sbjct: 1495 EKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ------EDSQG 1548
Query: 1021 PGVDRSPFAKSLGHSRGEADLFDSGDI---------FSTGTGSQSVERTKPKAKIAENPA 1071
G + K + + D S D S+ T SQ E TK K KI
Sbjct: 1549 SGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAG-- 1606
Query: 1072 NPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQ--KVKKN 1129
K S D+D A + +++ DEDD D+ ++K
Sbjct: 1607 --------KHRRLTRKSSTSIDED---------AGRRHSW---HDEDDEAFDESPELKYR 1646
Query: 1130 ETKSNSQQDVILT----TQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDI-FAD 1184
ETKS +++++T + ++ +T A K S ++ +K+ +L FD+ ++
Sbjct: 1647 ETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSL---YFDEEPELEMES 1703
Query: 1185 LTVKPKEKSK----KKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHK 1238
LT P+++S+ + A S SS + + P + ++ + + H+
Sbjct: 1704 LTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHR 1761
Score = 33.5 bits (75), Expect = 1.3
Identities = 58/282 (20%), Positives = 105/282 (37%), Gaps = 31/282 (10%)
Query: 333 AASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTA 392
AA + + K P+ S + P + D + D+ S S S G + S A
Sbjct: 4181 AAILYQKQSKHKKSLIDPKMSKFSPI------QESRDLEPDYSSYMTSSTSSIGGISSRA 4234
Query: 393 DIFGDE----------EGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSE 442
+ D+ + F ++ + T+ T + + E SS +PSS
Sbjct: 4235 RLLQDDITFGLRKNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSR 4294
Query: 443 TKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKK 502
+ GL D D SS S+ +LK + S + + +L + +
Sbjct: 4295 PSSVYGL--DLSIKRD--SSSSSLRLKAQEAEALDVSFSHASSSARTKPTSLPISQSRGR 4350
Query: 503 QTLCLQAQREEK-----AKASELSKKKASALL-FSSDEEDQW----NIPASQTHLASDSR 552
+ Q EE + +++ A L S+D DQ+ ++P Q H+ +SR
Sbjct: 4351 IPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREESR 4410
Query: 553 SKGEPRDSGTLQSQEAKAVKKTSLFE-EDEEDDLFAIAKDSQ 593
++G RD + A+ + + EE D F ++S+
Sbjct: 4411 TRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPRESR 4452
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 51.6 bits (122), Expect = 5e-06
Identities = 65/292 (22%), Positives = 120/292 (41%), Gaps = 50/292 (17%)
Query: 404 KEKAVASPEATVSQTDENKARAEKKVTLSSSKNLK---PSSETKTQKGLFSDEEDSEDLF 460
K V+S + S+ +K + + L+ SS+ + +DEEDS
Sbjct: 106 KSGTVSSQKQPASKATSDKTDSALNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNI 165
Query: 461 SSQSASKLKGASLLPGKLPTSVSLFDDEDE--------EDNLFGGTAAKKQTLCLQAQRE 512
+++ K ++ K P + D+ED +D T + ++ L+A +
Sbjct: 166 ATEIKDGEKSGTVSSQKQPALKATTDEEDSVLNIATEIKDGEKSETVSSQKQPALKATTD 225
Query: 513 EK-------------AKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRD 559
E+ K+ +S +K AL +SDE+D + ++ +R K +
Sbjct: 226 EEDSVSIIATEIKDGEKSGTVSSRKKPALKATSDEKDSF---------SNITREKKDGEI 276
Query: 560 SGTLQSQEAKAVKKTSLFEEDEEDDLFAIA--KDSQKKTQRVS-------LLFEDDVDSR 610
S T+ S++ +K TS DEED + IA K+ +KT+RVS D+ DS
Sbjct: 277 SRTVTSEKPAGLKATS----DEEDSVLNIARGKEDGEKTRRVSSRKKPALKATSDEKDS- 331
Query: 611 GSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAK 662
F + + S+ PP L + +E+++ L + +K E ++
Sbjct: 332 ---FSNITREKKDGETSRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSR 380
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 51.6 bits (122), Expect = 5e-06
Identities = 146/698 (20%), Positives = 251/698 (35%), Gaps = 127/698 (18%)
Query: 3 RLSGKSVRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQ 62
+LSGK EV + + EK++ KT+ K KVQ+ GL + F +
Sbjct: 885 KLSGKEQSFTSLEVRK--VAETKEKSKHLKTKTCK------KVQD----GLSDIAEKFLK 932
Query: 63 LDIKAGNSDSEEDDANGRVELILEPKDL---YIDRPLPYLI---GSKLFMEQEDV----- 111
D S+ ++ + E +P D I Y G++ E+E++
Sbjct: 933 KDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPK 992
Query: 112 GLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDG- 170
G+ ++ + I D +K++E SD +A S + + + S++++ +G
Sbjct: 993 GIKQIKNGTTDGEKKSKKIRDKTSKKKDELSD--YAEKSTGKGD--SCDSSEDKKSKNGA 1048
Query: 171 -------CDLFADSEKEEEDIEDIEENTRPKRSRPTSFAD------ELAARIKGDAVGRV 217
C L S ++ +D + + + +D EL R +
Sbjct: 1049 YGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNT 1108
Query: 218 DEEPTTLPSGEAKPRKTLKEKKERRTPS--------DDEEDNLFTPPKLTDEDFSPFGSG 269
E + S +A+ +KK++RT S + + ++L T K D + S
Sbjct: 1109 KEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSS 1168
Query: 270 GGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSK-------PGKKIPAGAVS 322
D ED++ + E D Q V E S G + + +V
Sbjct: 1169 -----------DIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVP 1217
Query: 323 VFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKP 382
V + D D + PE +K L D+DG DD+ P
Sbjct: 1218 VTVDDDD-----------DDNDPENRIAKKMLLEEIKANLSSDEDGSSDDE----PEEGK 1262
Query: 383 SKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKAR-----AEKKVTLSSS--- 434
+TGK GDEE K + E+ + K R K+T+S
Sbjct: 1263 KRTGKQNEENP--GDEEA-----KNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESG 1315
Query: 435 --KNLKPSS--ETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDE 490
K KP E K + EDSED +S + + + P + S E E
Sbjct: 1316 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1375
Query: 491 EDNLFGGTAAKKQTLCLQ--AQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLA 548
E+ K++ + +Q + E K+ + E ++K +EE++ +
Sbjct: 1376 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEE----EEEEEEEEEEEEEDENDD 1431
Query: 549 SDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVD 608
S S KG + L+ + + + +L EE+E A + ++K + V + ED
Sbjct: 1432 SKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREV-IEIED--- 1487
Query: 609 SRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKE 646
+ PT P TK +L DEE KE
Sbjct: 1488 -------ASPTKCPITTKL---------VLDEDEETKE 1509
Score = 46.2 bits (108), Expect = 2e-04
Identities = 183/926 (19%), Positives = 333/926 (35%), Gaps = 129/926 (13%)
Query: 335 SVPSMKEPQKP------EQPTPRKSPYGPPPTGLFDDDDGDDD----DDFFSAPHSKPSK 384
SVP K+ ++ + P P K P + + D D+ + HS S
Sbjct: 654 SVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSD 713
Query: 385 T--GKVQSTADIFGD---EEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKP 439
T ++ + D + G K K + S D K ++ K +S K
Sbjct: 714 TDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKR--- 770
Query: 440 SSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTA 499
+T+++ + E + E +S SK+ A ++P + EDE+ + G
Sbjct: 771 --QTQSESSNYDSELEKE----IKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDN 824
Query: 500 AKKQTLCLQAQREEKAKASELSKKKASALLFSSDE----------EDQWNIPASQTHLAS 549
+ L + + +S+ +++K FSS E E + +P Q AS
Sbjct: 825 QGHKNL-----KTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASAS 879
Query: 550 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDE-----------EDDLFAIAKDSQKKTQR 598
+ G + SG QS + V+K + +E +D L IA+ KK Q
Sbjct: 880 ---TDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQS 936
Query: 599 VSLLFEDDVDSRGSLFGSPPTSVPPATKKK--------ETVSEAPPLLFSDEEEKEAQLG 650
+ D + S G+ P KKK E+ S+ L EE G
Sbjct: 937 DE---TSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKG 993
Query: 651 VKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDK-GTKPRT 709
+K + ++ K R D +K+ L + + T K SS K G R
Sbjct: 994 IKQIKNGTTDGEKKSKKIR-DKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGRE 1052
Query: 710 KTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDP 769
K L + K +D + + + K G ++ L +L++ +
Sbjct: 1053 KKRCKLLGKSSRKRQDCSSSDTEKYSM----------KEDGCNSSDKRLKRIELRERRN- 1101
Query: 770 DVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQK 829
+ + TK E GS D E+ + K Q +KK V+ K+ +S +
Sbjct: 1102 ----LSSKRNTK--EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTST 1155
Query: 830 HPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQIS 889
+ + + Q+S G + +I + NL ++ ++ +
Sbjct: 1156 KRKQADITSSSSSDIEDDDQNSIG----EGSSDEQKIKPVTENLVLSSHTGFCQSSGDEA 1211
Query: 890 EVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGK 949
K V P + + +L +A +S D +D K R + +
Sbjct: 1212 LSKSV-PVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNE 1270
Query: 950 RRPQTRAARRLAAQES-SETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEAL 1008
P A+ ES S++E+ PR R +L + GE E+
Sbjct: 1271 ENPGDEEAKNQVNSESDSDSEESKKPR----------YRHRLLRHKLTVSDGESGEEK-- 1318
Query: 1009 AAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPK---AK 1065
P E V G +R K ++D +SG + S+S + +P+ AK
Sbjct: 1319 --KTKPKEHKEVKGRNR---RKVSSEDSEDSDFQESG---VSEEVSESEDEQRPRTRSAK 1370
Query: 1066 IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQK 1125
AE N + K + E SS ++ S + + K+ E+E++ +++
Sbjct: 1371 KAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEE----EEEEEEEEEEE 1426
Query: 1126 VKKNETKSNSQQDVILTTQDIFEDDIFATE---AIKPSQKTREK--EKTLESNLFDDNID 1180
+ +++KS + + + I +DD TE A+K ++ R++ E+ E + I+
Sbjct: 1427 DENDDSKSPGKGRKKI--RKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIE 1484
Query: 1181 IFADLTVKPKEKSKKKVEAKSIFDDD 1206
I + +K + K + D+D
Sbjct: 1485 I------EDASPTKCPITTKLVLDED 1504
Score = 30.8 bits (68), Expect = 8.5
Identities = 27/127 (21%), Positives = 51/127 (40%), Gaps = 10/127 (7%)
Query: 119 EEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSE 178
+E S ++ + + EEEKEEEE +E+ + ++N D + G
Sbjct: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEN------DDSKSPGKGRKKIRKIL 1446
Query: 179 KEEEDIEDIEENTRPKRSRPTSFADELAARIK-GDAVGRVDEEPTTLPSGEAKPRKTLKE 237
K+++ + + + + R A+ R K + + D PT P + L E
Sbjct: 1447 KDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCP---ITTKLVLDE 1503
Query: 238 KKERRTP 244
+E + P
Sbjct: 1504 DEETKEP 1510
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 51.6 bits (122), Expect = 5e-06
Identities = 146/698 (20%), Positives = 251/698 (35%), Gaps = 127/698 (18%)
Query: 3 RLSGKSVRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQ 62
+LSGK EV + + EK++ KT+ K KVQ+ GL + F +
Sbjct: 923 KLSGKEQSFTSLEVRK--VAETKEKSKHLKTKTCK------KVQD----GLSDIAEKFLK 970
Query: 63 LDIKAGNSDSEEDDANGRVELILEPKDL---YIDRPLPYLI---GSKLFMEQEDV----- 111
D S+ ++ + E +P D I Y G++ E+E++
Sbjct: 971 KDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPK 1030
Query: 112 GLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDG- 170
G+ ++ + I D +K++E SD +A S + + + S++++ +G
Sbjct: 1031 GIKQIKNGTTDGEKKSKKIRDKTSKKKDELSD--YAEKSTGKGD--SCDSSEDKKSKNGA 1086
Query: 171 -------CDLFADSEKEEEDIEDIEENTRPKRSRPTSFAD------ELAARIKGDAVGRV 217
C L S ++ +D + + + +D EL R +
Sbjct: 1087 YGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNT 1146
Query: 218 DEEPTTLPSGEAKPRKTLKEKKERRTPS--------DDEEDNLFTPPKLTDEDFSPFGSG 269
E + S +A+ +KK++RT S + + ++L T K D + S
Sbjct: 1147 KEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSS 1206
Query: 270 GGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSK-------PGKKIPAGAVS 322
D ED++ + E D Q V E S G + + +V
Sbjct: 1207 -----------DIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVP 1255
Query: 323 VFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKP 382
V + D D + PE +K L D+DG DD+ P
Sbjct: 1256 VTVDDDD-----------DDNDPENRIAKKMLLEEIKANLSSDEDGSSDDE----PEEGK 1300
Query: 383 SKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKAR-----AEKKVTLSSS--- 434
+TGK GDEE K + E+ + K R K+T+S
Sbjct: 1301 KRTGKQNEENP--GDEEA-----KNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESG 1353
Query: 435 --KNLKPSS--ETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDE 490
K KP E K + EDSED +S + + + P + S E E
Sbjct: 1354 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1413
Query: 491 EDNLFGGTAAKKQTLCLQ--AQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLA 548
E+ K++ + +Q + E K+ + E ++K +EE++ +
Sbjct: 1414 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEE----EEEEEEEEEEEEEDENDD 1469
Query: 549 SDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVD 608
S S KG + L+ + + + +L EE+E A + ++K + V + ED
Sbjct: 1470 SKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREV-IEIED--- 1525
Query: 609 SRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKE 646
+ PT P TK +L DEE KE
Sbjct: 1526 -------ASPTKCPITTKL---------VLDEDEETKE 1547
Score = 46.2 bits (108), Expect = 2e-04
Identities = 183/926 (19%), Positives = 333/926 (35%), Gaps = 129/926 (13%)
Query: 335 SVPSMKEPQKP------EQPTPRKSPYGPPPTGLFDDDDGDDD----DDFFSAPHSKPSK 384
SVP K+ ++ + P P K P + + D D+ + HS S
Sbjct: 692 SVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSD 751
Query: 385 T--GKVQSTADIFGD---EEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKP 439
T ++ + D + G K K + S D K ++ K +S K
Sbjct: 752 TDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKR--- 808
Query: 440 SSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTA 499
+T+++ + E + E +S SK+ A ++P + EDE+ + G
Sbjct: 809 --QTQSESSNYDSELEKE----IKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDN 862
Query: 500 AKKQTLCLQAQREEKAKASELSKKKASALLFSSDE----------EDQWNIPASQTHLAS 549
+ L + + +S+ +++K FSS E E + +P Q AS
Sbjct: 863 QGHKNL-----KTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASAS 917
Query: 550 DSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDE-----------EDDLFAIAKDSQKKTQR 598
+ G + SG QS + V+K + +E +D L IA+ KK Q
Sbjct: 918 ---TDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQS 974
Query: 599 VSLLFEDDVDSRGSLFGSPPTSVPPATKKK--------ETVSEAPPLLFSDEEEKEAQLG 650
+ D + S G+ P KKK E+ S+ L EE G
Sbjct: 975 DE---TSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKG 1031
Query: 651 VKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDK-GTKPRT 709
+K + ++ K R D +K+ L + + T K SS K G R
Sbjct: 1032 IKQIKNGTTDGEKKSKKIR-DKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGRE 1090
Query: 710 KTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDP 769
K L + K +D + + + K G ++ L +L++ +
Sbjct: 1091 KKRCKLLGKSSRKRQDCSSSDTEKYSM----------KEDGCNSSDKRLKRIELRERRN- 1139
Query: 770 DVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQK 829
+ + TK E GS D E+ + K Q +KK V+ K+ +S +
Sbjct: 1140 ----LSSKRNTK--EIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTST 1193
Query: 830 HPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQIS 889
+ + + Q+S G + +I + NL ++ ++ +
Sbjct: 1194 KRKQADITSSSSSDIEDDDQNSIG----EGSSDEQKIKPVTENLVLSSHTGFCQSSGDEA 1249
Query: 890 EVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGK 949
K V P + + +L +A +S D +D K R + +
Sbjct: 1250 LSKSV-PVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNE 1308
Query: 950 RRPQTRAARRLAAQES-SETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEAL 1008
P A+ ES S++E+ PR R +L + GE E+
Sbjct: 1309 ENPGDEEAKNQVNSESDSDSEESKKPR----------YRHRLLRHKLTVSDGESGEEK-- 1356
Query: 1009 AAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPK---AK 1065
P E V G +R K ++D +SG + S+S + +P+ AK
Sbjct: 1357 --KTKPKEHKEVKGRNR---RKVSSEDSEDSDFQESG---VSEEVSESEDEQRPRTRSAK 1408
Query: 1066 IAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNTFPLLEDEDDLFTDQK 1125
AE N + K + E SS ++ S + + K+ E+E++ +++
Sbjct: 1409 KAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEE----EEEEEEEEEEE 1464
Query: 1126 VKKNETKSNSQQDVILTTQDIFEDDIFATE---AIKPSQKTREK--EKTLESNLFDDNID 1180
+ +++KS + + + I +DD TE A+K ++ R++ E+ E + I+
Sbjct: 1465 DENDDSKSPGKGRKKI--RKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIE 1522
Query: 1181 IFADLTVKPKEKSKKKVEAKSIFDDD 1206
I + +K + K + D+D
Sbjct: 1523 I------EDASPTKCPITTKLVLDED 1542
Score = 30.8 bits (68), Expect = 8.5
Identities = 27/127 (21%), Positives = 51/127 (40%), Gaps = 10/127 (7%)
Query: 119 EEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSE 178
+E S ++ + + EEEKEEEE +E+ + ++N D + G
Sbjct: 1431 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDEN------DDSKSPGKGRKKIRKIL 1484
Query: 179 KEEEDIEDIEENTRPKRSRPTSFADELAARIK-GDAVGRVDEEPTTLPSGEAKPRKTLKE 237
K+++ + + + + R A+ R K + + D PT P + L E
Sbjct: 1485 KDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCP---ITTKLVLDE 1541
Query: 238 KKERRTP 244
+E + P
Sbjct: 1542 DEETKEP 1548
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 51.2 bits (121), Expect = 6e-06
Identities = 92/427 (21%), Positives = 159/427 (37%), Gaps = 52/427 (12%)
Query: 163 DEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPT 222
D++EDD G D F D + +D +E + D + A + G+ + T
Sbjct: 87 DDDEDDSGDDTFGDDDSGPGP-KDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDT 145
Query: 223 TLPSGEAKPRKTLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDD 282
T S E + K E + + E ++E + GS G G DD
Sbjct: 146 TSESRELDNEDRVDSKPEGGDSTQESE---------SEEHWVGGGSDGESSHGDGSELDD 196
Query: 283 EDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEP 342
E +SD D ++ S + S + G K + +T G + +
Sbjct: 197 EGMQSD-------DPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQL-----L 244
Query: 343 QKPEQPTPRKSPYG-PPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGD 401
+ P + RKS DD++ ++ S +S TG Q D GD + D
Sbjct: 245 EHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQED 304
Query: 402 ----LFKEK--------AVASPEATVSQTDENKARAEKKVTLSSSKNLKP-SSETKTQKG 448
L +E+ + +S EA +S + + E+ V+ S N P +S + Q+
Sbjct: 305 SKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQED 364
Query: 449 LFSDEEDSEDLFS-SQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCL 507
S EEDS S S+S S+ + A + + E++N + +
Sbjct: 365 SDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSA 424
Query: 508 QAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQE 567
++Q EE + S + S S +ED ++ + SK + G L++ E
Sbjct: 425 ESQSEESHSEEDDSDSQDS----SRSKED-----------SNSTESKSSSEEDGQLKNIE 469
Query: 568 AKAVKKT 574
++ K T
Sbjct: 470 IESRKLT 476
Score = 39.7 bits (91), Expect = 0.018
Identities = 90/407 (22%), Positives = 148/407 (36%), Gaps = 80/407 (19%)
Query: 364 DDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEE--GDLFKEKAVASPEATVSQTDEN 421
DDD+ D DD F S P + + G +E D + ++P+ S D
Sbjct: 87 DDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQD-- 144
Query: 422 KARAEKKVTLSSSKNL--KPSSETKTQKGLFSDEEDSEDLF----SSQSASKLKGASLLP 475
T S S+ L + ++K + G + E +SE+ + S +S G+ L
Sbjct: 145 --------TTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSEL-- 194
Query: 476 GKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFS---- 531
+ D+ E G + + E ++ + S LL
Sbjct: 195 ----DDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRK 250
Query: 532 -------SDEEDQWNIPASQT--HLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEE 582
S+E+D+ + + T + SDS RD+G SQ + K S +ED +
Sbjct: 251 IFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGL--SQPRRDSKGDS--QEDSK 306
Query: 583 DDLFAIAKDSQKKTQRVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEA------PP 636
++L SQ+++Q V D S S + + + ++E VSE+ P
Sbjct: 307 ENL------SQEESQNV-----DGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPT 355
Query: 637 LLF--------SDEEEKEAQLGVKSVDKKVESA----KESLKFGR------TDVAESEKE 678
+ S EE+ L + + E A ESL F D S +E
Sbjct: 356 TSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQE 415
Query: 679 GLLTRS----AQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEED 721
GL + S +Q HS+ S S +K + + S EED
Sbjct: 416 GLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEED 462
Score = 39.3 bits (90), Expect = 0.024
Identities = 83/411 (20%), Positives = 149/411 (36%), Gaps = 68/411 (16%)
Query: 268 SGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVK--EESSSSKPGKKIPAGAVSVFL 325
+GG S GKG D +D+E D + D +G K +E +S+ G
Sbjct: 72 AGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSD---------- 121
Query: 326 GDTDVFGAASVPSMKEPQKPEQPTPRKS-------PYGPPPTGLFDDDDGDDDDDFFSAP 378
D+D AS S + Q Q T +S P G + + ++ +
Sbjct: 122 EDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGG 181
Query: 379 HSKPSKTGKVQSTAD--IFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSS--S 434
S G D + D+ + E+ + + ++ E+ +E+ T S S
Sbjct: 182 SDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGS 241
Query: 435 KNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNL 494
+ L+ S +K S+E+D +L + + ++K D E N
Sbjct: 242 QLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVK----------------SDSTENSN- 284
Query: 495 FGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSK 554
+ T Q +R+ K + E SK+ S +E + P+S++ ++ S+
Sbjct: 285 ------SRDTGLSQPRRDSKGDSQEDSKEN-----LSQEESQNVDGPSSESSQEANLSSQ 333
Query: 555 GEPRDSGTLQSQEAKA--VKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSRGS 612
+S E++ T+ + ED+ED + S + S E+ DS S
Sbjct: 334 ENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESS 393
Query: 613 LFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKE 663
+ E E+P ++E +Q G++S ES E
Sbjct: 394 ----------ESLNFSEESPESP-----EDENSSSQEGLQSHSSSAESQSE 429
Score = 34.7 bits (78), Expect = 0.59
Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 26/186 (13%)
Query: 69 NSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRG 128
N S+E+ + + E++ E + D P P + +QED SSEE S +
Sbjct: 329 NLSSQENSSESQEEVVSESRG---DNPDPT---TSYVEDQEDSD----SSEEDSSHTLSH 378
Query: 129 SIVDTEEEKEEEESDE--DFAHHS-DNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIE 185
S ++ EE+ + ES E +F+ S ++ ++ +++ + + ++ EED
Sbjct: 379 SKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDS 438
Query: 186 DIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPS 245
D ++++R K D + K + EE L + E + RK + + P
Sbjct: 439 DSQDSSRSKE-------DSNSTESKSSS-----EEDGQLKNIEIESRKLTVDAYHNK-PI 485
Query: 246 DDEEDN 251
D++DN
Sbjct: 486 GDQDDN 491
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 50.8 bits (120), Expect = 8e-06
Identities = 96/488 (19%), Positives = 182/488 (37%), Gaps = 42/488 (8%)
Query: 611 GSLFGSPPTSVPPATKKKETVSEA--PPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFG 668
G G+ P A + + SE P D +E E + +S D + A+
Sbjct: 1827 GQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGE---- 1882
Query: 669 RTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNI 728
A+ E E + T A+ V+ + + +K +P T++V +L E ED+ E +
Sbjct: 1883 ----AQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGA 1938
Query: 729 IQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVG 788
+E + + P+S E++ S + +++ P+ + + + + G
Sbjct: 1939 EAQEAEEAAQEAEGQTQPES-------EVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 789 SLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETP 848
+ ED + + +E+ + + + ++G +K + +
Sbjct: 1992 EAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQK--TEGDAQ 2049
Query: 849 QDSSGL-APFKTKEPSTRIGKIQ-ANLAINPAALLPTAASQISEVKPVLPELAFPSS--E 904
+S G+ AP +E G++Q A +P + A E +P + P + E
Sbjct: 2050 PESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGE 2109
Query: 905 HRRSHGLESVPVLPGSGE---AGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLA 961
+++ G+E+ P G + G+ S G+ +P++
Sbjct: 2110 AQKAEGIEA-PETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQE 2168
Query: 962 AQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTE-EALAAAAAPWEGGPV 1020
A+E ++ E G A A+G P + A GE E E + A A E P
Sbjct: 2169 AEEEAQPE----LEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPE 2224
Query: 1021 PGVDRSPFA------KSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPP 1074
P +P A +S G ++GE S G G QS E ++ + + E+ PP
Sbjct: 2225 PEGVETPEAEGEAQPESEGETQGEK---KGSPQVSLGDG-QSEEASESSSPVPEDRPTPP 2280
Query: 1075 VGGKAKSP 1082
+P
Sbjct: 2281 PSPGGDTP 2288
Score = 50.1 bits (118), Expect = 1e-05
Identities = 109/493 (22%), Positives = 185/493 (37%), Gaps = 75/493 (15%)
Query: 18 EPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDA 77
E + EAE+ Q ++ + + +++ + QEA ++ E D++A ++ E +A
Sbjct: 1959 EVIESQEAEEEAQPESEDVEALEVEVETQEAEG------EAQPESEDVEAPEAEGEMQEA 2012
Query: 78 NGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEK 137
+ P+ ++ P G + QE G + + + SD + EEE
Sbjct: 2013 EEEAQ----PESDGVEAQ-PKSEGEEA---QEVEGETQKTEGDAQPESDGVEAPEAEEEA 2064
Query: 138 EEEESDEDFAH---HSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPK 194
+E E + A H ++E + + + +G + ++E E + E IE
Sbjct: 2065 QEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEA-PEAEGEAQKAEGIEAPETEG 2123
Query: 195 RSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFT 254
++P S E A +G+A + GEA+P E +E + E + +
Sbjct: 2124 EAQPESEGIE-APEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEA 2182
Query: 255 PPKLTDEDFSPFGSG-------GGLFSGGKGLFDDE-DEESDLFTEAPQDRQAGASVKEE 306
P + + P G G +G+ E +EE+ E + +A + E
Sbjct: 2183 PE--AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPE 2240
Query: 307 SSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDD 366
S G+K G+ V LGD +E + P P P PP G
Sbjct: 2241 SEGETQGEK--KGSPQVSLGD---------GQSEEASESSSPVPEDRPTPPPSPG----- 2284
Query: 367 DGDDDDDFFSAPHSKP-SKTGKVQSTADIFG-----DEEGDLFKEKAVASPEATVSQTDE 420
GD PH +P S+TG S A +G D E D SP+A + T
Sbjct: 2285 -GD-------TPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGD-TRSPDAKSTGT-- 2333
Query: 421 NKARAEKKVTLSSSKNLKPSSETKTQK----GLFSDEEDSEDLFSSQSASKLKGASLLPG 476
AE+K T + P S T Q+ G + E+ + + + Q L SL P
Sbjct: 2334 --PHAERKAT-----RMYPESSTSEQEEAPLGSRTPEQGASEGYDLQEDQAL--GSLAPT 2384
Query: 477 KLPTSVSLFDDED 489
+ F +D
Sbjct: 2385 EAVGRADGFGQDD 2397
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 49.7 bits (117), Expect = 2e-05
Identities = 121/611 (19%), Positives = 223/611 (36%), Gaps = 80/611 (13%)
Query: 136 EKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKR 195
E EE+E D++ + + ++H ++ EE D L+ D ++EE ++ EE+ + +
Sbjct: 4741 ELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEE---DEEEEDNKTEE 4797
Query: 196 SRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPS--------DD 247
+ P ++ K D L SG + K+ ++KKE + + +D
Sbjct: 4798 TGPGMDEEDSELVAKDD----------NLDSGNSNKDKSQQDKKEEKEEAEADDGGQGED 4847
Query: 248 EEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASV-KEE 306
+ + + + P+ + L +D D +D+ G EE
Sbjct: 4848 KINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLD-----SEDKNGGEDTDNEE 4902
Query: 307 SSSSKP----GKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGL 362
P K AG + G+T+ E Q P++P S G
Sbjct: 4903 GEEENPLEIKEKPEEAGHEAEERGETET-------DQNESQSPQEPEEGPSE-DDKAEGE 4954
Query: 363 FDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENK 422
+ D G DD D +A H + + QS + D+E D +E P Q E +
Sbjct: 4955 EEMDTGADDQDGDAAQHPEEHSEEQQQSVEE--KDKEAD--EEGGENGPADQGFQPQEEE 5010
Query: 423 ARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGAS--LLPGKLPT 480
R + S ++ P E +K S + + + A +L GA+ GK
Sbjct: 5011 ERED-----SDTEEQVP--EALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEH 5063
Query: 481 SVSLFD---DEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQ 537
D E E N A++K T + +K A S +
Sbjct: 5064 GSGAADANQAEGHESNFIAQLASQKHT---------RKNTQSFKRKPGQADNERSMGDHN 5114
Query: 538 WNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQ 597
+ + +DS ++ P Q ++A A + + + + +A Q+++
Sbjct: 5115 ERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSA 5174
Query: 598 RVSLLFEDDVDSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKE---AQLGVKSV 654
+ S +++ + +L T+++E A EE K A LG +
Sbjct: 5175 KDSGKDQEEEEIEDTLMD---------TEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEM 5225
Query: 655 DKKVESAK-ESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVL 713
+ ++++ K E + RTD A E E ++E+ H+ + D +P K V
Sbjct: 5226 EVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHT---AHQFLMDTIFQPFLKDVN 5282
Query: 714 SLFDEEEDKME 724
L E E ++E
Sbjct: 5283 ELRQELERQLE 5293
Score = 44.3 bits (103), Expect = 7e-04
Identities = 125/645 (19%), Positives = 239/645 (37%), Gaps = 94/645 (14%)
Query: 139 EEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRP 198
E E +D + NE+ T +E+D + D +D + E+ IE E+
Sbjct: 4682 EGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGE 4741
Query: 199 TSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFTPPKL 258
+E + + G +D+ L EA +K + R DD+E+
Sbjct: 4742 LEEQEEDDEKSDSEG-GDLDKHMGDLNGEEA-------DKLDERLWGDDDEEE-----DE 4788
Query: 259 TDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPA 318
+ED +G G+ DEE + +G S K++S K +K A
Sbjct: 4789 EEEDNKTEETGPGM-----------DEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEA 4837
Query: 319 GAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAP 378
A G+ + + + P P P L DD + D + +
Sbjct: 4838 EADDGGQGEDKI--NEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGG 4895
Query: 379 HSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLK 438
++ G+ ++ +I E E + E ++TD+N++++ ++ S++ K
Sbjct: 4896 EDTDNEEGEEENPLEIKEKPE-----EAGHEAEERGETETDQNESQSPQEPEEGPSEDDK 4950
Query: 439 PSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGT 498
E + G +D++D + + S+ + SV D E +E+ G
Sbjct: 4951 AEGEEEMDTG--ADDQDGDAAQHPEEHSE---------EQQQSVEEKDKEADEEGGENGP 4999
Query: 499 AAKKQTLCLQAQREEKAKAS-------ELSKKKASALLFSSDEEDQWNIPASQTHLASDS 551
A + Q Q EE+ + S E ++K A + E+ N A + A+
Sbjct: 5000 ADQG----FQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPE 5055
Query: 552 RSKG-EPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFE---DDV 607
+ +G E SG + +A+ + F SQK T++ + F+
Sbjct: 5056 KEQGKEEHGSGAADANQAEG-----------HESNFIAQLASQKHTRKNTQSFKRKPGQA 5104
Query: 608 DSRGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKF 667
D+ S+ G V + +T S A ++ +AQ+ + ++ ++
Sbjct: 5105 DNERSM-GDHNERVHKRLRTVDTDSHAEQ---GPAQQPQAQVEDADAFEHIKQGSDAYDA 5160
Query: 668 GRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQN 727
DVA E++ +SA+++ K D+ + T++ ++EE K D
Sbjct: 5161 QTYDVASKEQQ----QSAKDSGK-----------DQEEEEIEDTLMDTEEQEEFKAAD-- 5203
Query: 728 IIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVD 772
+ Q +E+ G G + E + + K ++D DP D
Sbjct: 5204 VEQLKPEEIKSGT-----TAPLGFDEMEVEIQTVKTEEDQDPRTD 5243
Score = 42.0 bits (97), Expect = 0.004
Identities = 115/538 (21%), Positives = 191/538 (35%), Gaps = 108/538 (20%)
Query: 13 DEEVEEPVLK--------AEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLD 64
DEE E V K + +K++Q+K E++E + + G Q D EQ+D
Sbjct: 4803 DEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAE--------ADDGGQGEDKINEQID 4854
Query: 65 IKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSS------ 118
+ ++E D +G E + EP+ L + L K E D GE +
Sbjct: 4855 -ERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKE 4913
Query: 119 ---EEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFA 175
E G +RG + E + + E+ D + +M +D DG
Sbjct: 4914 KPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEE--EMDTGADDQDGDAAQH 4971
Query: 176 DSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDE--EPTTLPSGEAKPRK 233
E EE + +EE + ADE +G G D+ +P
Sbjct: 4972 PEEHSEEQQQSVEEKDKE--------ADE-----EGGENGPADQGFQP------------ 5006
Query: 234 TLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEA 293
+++E R SD EE P L ++ + G +G + + + +L A
Sbjct: 5007 ---QEEEEREDSDTEEQ---VPEALERKEHASCGQ-----TGVENM--QNTQAMELAGAA 5053
Query: 294 PQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKS 353
P+ Q KEE S G S F+ A + S K +K Q RK
Sbjct: 5054 PEKEQG----KEEHGSGAADANQAEGHESNFI--------AQLASQKHTRKNTQSFKRKP 5101
Query: 354 PYGPPPTGLFDDDDG--------DDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKE 405
+ D ++ D D P +P A + E+ D F E
Sbjct: 5102 GQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQ--------AQV---EDADAF-E 5149
Query: 406 KAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSA 465
+A +QT + ++ +++ S K+ E + + L EE E F +
Sbjct: 5150 HIKQGSDAYDAQTYDVASKEQQQSAKDSGKD---QEEEEIEDTLMDTEEQEE--FKAADV 5204
Query: 466 SKLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKK 523
+LK + G T+ L DE E + T + +A +E + + E S++
Sbjct: 5205 EQLKPEEIKSG---TTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRE 5259
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 48.9 bits (115), Expect = 3e-05
Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 10/140 (7%)
Query: 132 DTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENT 191
+ EEE+EEEE +E+ D E+ + EEE+++ + + E+EE ++E+ EE
Sbjct: 890 EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE 949
Query: 192 RPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKER---------- 241
+ ++L G V P TLP P K + E
Sbjct: 950 DEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEV 1009
Query: 242 RTPSDDEEDNLFTPPKLTDE 261
P +EE T P L E
Sbjct: 1010 EEPGTEEERGADTAPTLAPE 1029
Score = 40.0 bits (92), Expect = 0.014
Identities = 44/252 (17%), Positives = 100/252 (39%), Gaps = 32/252 (12%)
Query: 217 VDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFTPPKLTDEDFSPFGSGGGLFSGG 276
++E+ T + + + +E++E ++EE+ F + +E++
Sbjct: 874 LEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEY------------- 920
Query: 277 KGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVF--LGDTDVFGAA 334
F++E+EE + F E ++ + +EE + +++ F G GA
Sbjct: 921 ---FEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAP 977
Query: 335 SVPSMKEPQKPEQPTPRKSPYGPPPTGLF-------DDDDGDDDDDFFSAPHSKPSKTGK 387
P++ P + P+ P P GL +++ D AP + PS+ G+
Sbjct: 978 PPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ-GE 1036
Query: 388 VQSTAD--IFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKT 445
V+ + G +L +E+ A P +T++ + + + + + ET+T
Sbjct: 1037 VEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEM----ETET 1092
Query: 446 QKGLFSDEEDSE 457
+ ++E +
Sbjct: 1093 EAEALQEKEQDD 1104
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.126 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,434,495
Number of Sequences: 37866
Number of extensions: 2954838
Number of successful extensions: 20111
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 692
Number of HSP's that attempted gapping in prelim test: 12431
Number of HSP's gapped (non-prelim): 4915
length of query: 1253
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1139
effective length of database: 13,930,794
effective search space: 15867174366
effective search space used: 15867174366
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.