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Search of human proteins with 153792590
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
sapiens]
(854 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s... 1707 0.0
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s... 1451 0.0
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens] 1263 0.0
gi|4507677 heat shock protein 90kDa beta, member 1 [Homo sapiens] 639 0.0
gi|155722983 TNF receptor-associated protein 1 [Homo sapiens] 196 6e-50
gi|221219020 NYD-SP11 protein [Homo sapiens] 65 3e-10
gi|55741661 hypothetical protein LOC57653 [Homo sapiens] 59 2e-08
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 57 9e-08
gi|34878777 ring finger protein 20 [Homo sapiens] 56 2e-07
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 55 2e-07
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 55 2e-07
gi|17975763 myelin transcription factor 1 [Homo sapiens] 52 2e-06
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 52 3e-06
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 51 4e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 50 1e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 50 1e-05
gi|4757900 calreticulin precursor [Homo sapiens] 49 3e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 49 3e-05
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 48 3e-05
gi|4758220 XAP-5 protein [Homo sapiens] 48 4e-05
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 47 6e-05
gi|215422388 death-domain associated protein isoform a [Homo sap... 47 6e-05
gi|215422366 death-domain associated protein isoform b [Homo sap... 47 6e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 47 6e-05
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 47 6e-05
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 47 8e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 47 8e-05
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 47 8e-05
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 47 8e-05
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 47 8e-05
>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
sapiens]
Length = 854
Score = 1707 bits (4420), Expect = 0.0
Identities = 854/854 (100%), Positives = 854/854 (100%)
Query: 1 MPPCSGGDGSTPPGPSLRDRDCPAQSAEYPRDRLDPRPGSPSEASSPPFLRSRAPVNWYQ 60
MPPCSGGDGSTPPGPSLRDRDCPAQSAEYPRDRLDPRPGSPSEASSPPFLRSRAPVNWYQ
Sbjct: 1 MPPCSGGDGSTPPGPSLRDRDCPAQSAEYPRDRLDPRPGSPSEASSPPFLRSRAPVNWYQ 60
Query: 61 EKAQVFLWHLMVSGSTTLLCLWKQPFHVSAFPVTASLAFRQSQGAGQHLYKDLQPFILLR 120
EKAQVFLWHLMVSGSTTLLCLWKQPFHVSAFPVTASLAFRQSQGAGQHLYKDLQPFILLR
Sbjct: 61 EKAQVFLWHLMVSGSTTLLCLWKQPFHVSAFPVTASLAFRQSQGAGQHLYKDLQPFILLR 120
Query: 121 LLMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDK 180
LLMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDK
Sbjct: 121 LLMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDK 180
Query: 181 IRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAF 240
IRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAF
Sbjct: 181 IRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAF 240
Query: 241 MEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGE 300
MEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGE
Sbjct: 241 MEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGE 300
Query: 301 PMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEK 360
PMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEK
Sbjct: 301 PMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEK 360
Query: 361 EDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWT 420
EDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWT
Sbjct: 361 EDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWT 420
Query: 421 RNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKK 480
RNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKK
Sbjct: 421 RNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKK 480
Query: 481 NNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVK 540
NNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVK
Sbjct: 481 NNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVK 540
Query: 541 KCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLK 600
KCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLK
Sbjct: 541 KCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLK 600
Query: 601 DYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEG 660
DYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEG
Sbjct: 601 DYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEG 660
Query: 661 KTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCC 720
KTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCC
Sbjct: 661 KTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCC 720
Query: 721 IVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKS 780
IVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKS
Sbjct: 721 IVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKS 780
Query: 781 VKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPP 840
VKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPP
Sbjct: 781 VKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPP 840
Query: 841 LEGDDDTSRMEEVD 854
LEGDDDTSRMEEVD
Sbjct: 841 LEGDDDTSRMEEVD 854
>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
sapiens]
Length = 732
Score = 1451 bits (3756), Expect = 0.0
Identities = 732/732 (100%), Positives = 732/732 (100%)
Query: 123 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 182
MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR
Sbjct: 1 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 60
Query: 183 YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 242
YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME
Sbjct: 61 YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 120
Query: 243 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 302
ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM
Sbjct: 121 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 180
Query: 303 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED 362
GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED
Sbjct: 181 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED 240
Query: 363 KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN 422
KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN
Sbjct: 241 KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN 300
Query: 423 PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN 482
PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN
Sbjct: 301 PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN 360
Query: 483 IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 542
IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC
Sbjct: 361 IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 420
Query: 543 LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY 602
LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY
Sbjct: 421 LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY 480
Query: 603 CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT 662
CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT
Sbjct: 481 CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT 540
Query: 663 LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV 722
LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV
Sbjct: 541 LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV 600
Query: 723 TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK 782
TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK
Sbjct: 601 TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK 660
Query: 783 DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE 842
DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE
Sbjct: 661 DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE 720
Query: 843 GDDDTSRMEEVD 854
GDDDTSRMEEVD
Sbjct: 721 GDDDTSRMEEVD 732
>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
Length = 724
Score = 1263 bits (3268), Expect = 0.0
Identities = 628/732 (85%), Positives = 684/732 (93%), Gaps = 8/732 (1%)
Query: 123 MPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIR 182
MPEE EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIR
Sbjct: 1 MPEEVHHG-----EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIR 55
Query: 183 YESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFME 242
YESLTDPSKLDSGKEL I++IPN Q+RTLT+VDTGIGMTKADLINNLGTIAKSGTKAFME
Sbjct: 56 YESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFME 115
Query: 243 ALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPM 302
ALQAGADISMIGQFGVGFYSAYLVAEKV VITKHNDDEQYAWESSAGGSFTVR D GEP+
Sbjct: 116 ALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPI 175
Query: 303 GRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKED 362
GRGTKVILHLKEDQTEYLEERR+KE+VKKHSQFIGYPITL++EKER+KE+SDDEAEE++
Sbjct: 176 GRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKG 235
Query: 363 KEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRN 422
EKE+E+K+ E+KP+IEDVGSDEE++ KKK KKIKEKYIDQEELNKTKPIWTRN
Sbjct: 236 ---EKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRN 292
Query: 423 PDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNN 482
PDDIT EEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF+PRRAPFDLFEN+KKKNN
Sbjct: 293 PDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNN 352
Query: 483 IKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 542
IKLYVRRVFIMD+C+ELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKN+VKKC
Sbjct: 353 IKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKC 412
Query: 543 LELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDY 602
LELF+ELAEDKENYKKFYE FSKN+KLGIHEDS NR++LSELLRY+TS SGDEM SL +Y
Sbjct: 413 LELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEY 472
Query: 603 CTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKT 662
+RMKE QK IYYITGE+K+QVANSAFVER+RK G EV+YM EPIDEYCVQQLKEF+GK+
Sbjct: 473 VSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKS 532
Query: 663 LVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIV 722
LVSVTKEGLELPEDEEEKKK EE K KFENLCK+MK+IL+KKVEKV +SNRLV+SPCCIV
Sbjct: 533 LVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIV 592
Query: 723 TSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVK 782
TSTYGWTANMERIMKAQALRDNSTMGYM AKKHLEINPDH I+ETLRQKAEADKNDK+VK
Sbjct: 593 TSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVK 652
Query: 783 DLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLE 842
DLV+LL+ETALLSSGFSLEDPQTH+NRIYRMIKLGLGIDED+ A++ +AAV +E+PPLE
Sbjct: 653 DLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIPPLE 712
Query: 843 GDDDTSRMEEVD 854
GD+D SRMEEVD
Sbjct: 713 GDEDASRMEEVD 724
>gi|4507677 heat shock protein 90kDa beta, member 1 [Homo sapiens]
Length = 803
Score = 639 bits (1648), Expect = 0.0
Identities = 345/729 (47%), Positives = 479/729 (65%), Gaps = 27/729 (3%)
Query: 137 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 196
E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR SLTD + L +
Sbjct: 71 EKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNE 130
Query: 197 ELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAGADIS- 251
EL + + +K+ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA + G S
Sbjct: 131 ELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSE 190
Query: 252 MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILH 311
+IGQFGVGFYSA+LVA+KV V +KHN+D Q+ WES + + G +GRGT + L
Sbjct: 191 LIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLV 250
Query: 312 LKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEE 371
LKE+ ++YLE IK +VKK+SQFI +PI ++ K E E+ +EEE KEE
Sbjct: 251 LKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKT--------ETVEEPMEEEEAAKEE 302
Query: 372 KESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEY 431
KE D ++ +EEEE+K K K KK+++ D E +N KPIW R ++ +EY
Sbjct: 303 KEESD----DEAAVEEEEEEK---KPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEY 355
Query: 432 GEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFEN--RKKKNNIKLYVRR 489
FYKS + + +D +A HF+ EG++ F+++LFVP AP LF+ KK + IKLYVRR
Sbjct: 356 KAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRR 415
Query: 490 VFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTEL 549
VFI D+ +++P+YLNF++GVVDS+DLPLN+SRE LQQ K+LKVIRK LV+K L++ ++
Sbjct: 416 VFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKI 475
Query: 550 AEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKEN 609
A+DK N F+++F NIKLG+ ED NR +L++LLR+ +S ++ SL Y RMKE
Sbjct: 476 ADDKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEK 534
Query: 610 QKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKE 669
Q IY++ G ++ + +S FVERL K G EVIY+ EP+DEYC+Q L EF+GK +V KE
Sbjct: 535 QDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKE 594
Query: 670 GLELPEDEEEKKKQEEKKTKFENLCKIMKD-ILEKKVEKVVVSNRLVTSPCCIVTSTYGW 728
G++ E E+ K+ +E + +FE L MKD L+ K+EK VVS RL SPC +V S YGW
Sbjct: 595 GVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGW 654
Query: 729 TANMERIMKAQAL---RDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLV 785
+ NMERIMKAQA +D ST Y + KK EINP H +I + ++ + D++DK+V DL
Sbjct: 655 SGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLA 714
Query: 786 ILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDD 845
++L+ETA L SG+ L D + + +RI RM++L L ID D ++ E D
Sbjct: 715 VVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDT 774
Query: 846 DTSRMEEVD 854
+ EE+D
Sbjct: 775 EQDEDEEMD 783
Score = 35.4 bits (80), Expect = 0.23
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Query: 330 KKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEE 389
K + I + L + + D +V ++ EE E+ E+ ++ ++ ED E DVG+DEEE
Sbjct: 733 KAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDED--EEMDVGTDEEE 790
Query: 390 EKKDGDKKKKKKI 402
E +K ++
Sbjct: 791 ETAKESTAEKDEL 803
Score = 34.7 bits (78), Expect = 0.39
Identities = 17/54 (31%), Positives = 30/54 (55%)
Query: 359 EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEEL 412
+ + K EE+ +EE E + ED DE+EE G ++++ KE +++EL
Sbjct: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803
>gi|155722983 TNF receptor-associated protein 1 [Homo sapiens]
Length = 704
Score = 196 bits (499), Expect = 6e-50
Identities = 120/421 (28%), Positives = 225/421 (53%), Gaps = 21/421 (4%)
Query: 406 YIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFV 465
Y++ +N + IW +P D+ ++ EFY+ + + H+ + L R++ +V
Sbjct: 286 YLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYV 345
Query: 466 PRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREML 525
P P +R+ +++ LY R+V I +++P++L FIRGVVDSED+PLN+SRE+L
Sbjct: 346 PDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELL 405
Query: 526 QQSKILKVIRKNLVKKCLELFTELA-EDKENYKKFYEQFSKNIKLGI--HEDSQNRKKLS 582
Q+S +++ +R L ++ ++ F + + +D E Y KF+E + ++ GI + + ++ ++
Sbjct: 406 QESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIA 465
Query: 583 ELLRYYTSA-SGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVI 641
+LLRY +SA ++ SL +Y +RM+ ++IYY+ + +S + E ++K EV+
Sbjct: 466 KLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVL 525
Query: 642 YMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQ--------EEKKTKFENL 693
+ E DE + L+EF+ K L+SV + + + +EEK + EK+T E L
Sbjct: 526 FCFEQFDELTLLHLREFDKKKLISVETD-IVVDHYKEEKFEDRSPAAECLSEKET--EEL 582
Query: 694 CKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAK 753
M+++L +V V V+ RL T P + G ++ Q L +
Sbjct: 583 MAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMG---AARHFLRMQQLAKTQEERAQLLQ 639
Query: 754 KHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRM 813
LEINP H++I+ L Q ++ + LV +YE A++++G ++DP+ R+ +
Sbjct: 640 PTLEINPRHALIKKLNQLRASEPGLAQL--LVDQIYENAMIAAGL-VDDPRAMVGRLNEL 696
Query: 814 I 814
+
Sbjct: 697 L 697
Score = 180 bits (456), Expect = 6e-45
Identities = 100/241 (41%), Positives = 156/241 (64%), Gaps = 11/241 (4%)
Query: 144 FQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLI 203
FQAE +L+ ++ + YS KE+F+RELISN+SDAL+K+R++ ++D L E+ I+L
Sbjct: 90 FQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALP---EMEIHLQ 146
Query: 204 PNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADIS--MIGQFGVGFY 261
N + T+TI DTGIGMT+ +L++NLGTIA+SG+KAF++ALQ A+ S +IGQFGVGFY
Sbjct: 147 TNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFY 206
Query: 262 SAYLVAEKVTVITKHNDDEQ--YAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEY 319
SA++VA++V V ++ Y W S G F + +G + GTK+I+HLK D E+
Sbjct: 207 SAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASG--VRTGTKIIIHLKSDCKEF 264
Query: 320 LEERRIKEIVKKHSQFIGYPITLFVEKERDKEV--SDDEAEEKEDKEEEKEKEEKESEDK 377
E R++++V K+S F+ +P+ L + + D + +E + EE + ++ DK
Sbjct: 265 SSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDK 324
Query: 378 P 378
P
Sbjct: 325 P 325
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 64.7 bits (156), Expect = 3e-10
Identities = 41/139 (29%), Positives = 84/139 (60%), Gaps = 12/139 (8%)
Query: 341 TLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKK 400
+L E E+ + +S +E EE+E++EE +E+E +E E++ + E+ G +++ EK++ +KKKKK
Sbjct: 2232 SLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKK 2291
Query: 401 KIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFR 460
K K+K EE+ + + ++ + ++ EE +SL+++ E+ + S+E +++ R
Sbjct: 2292 KEKKK----EEVQEKEEVFEEKEEIMSEEE----TESLSDEEEEE---ESCSLEEEVD-R 2339
Query: 461 ALLFVPRRAPFDLFENRKK 479
+ + F L E R+K
Sbjct: 2340 EKEILKKEKQFKLQEQRRK 2358
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/87 (24%), Positives = 50/87 (57%)
Query: 344 VEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 403
V++ +E +E E D+ E++E E E++ E E+ +EE +++ ++K++++ +
Sbjct: 2217 VDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276
Query: 404 EKYIDQEELNKTKPIWTRNPDDITNEE 430
EK +++EE K K + +++ +E
Sbjct: 2277 EKQVEKEEEEKKKKKKEKKKEEVQEKE 2303
Score = 41.2 bits (95), Expect = 0.004
Identities = 30/114 (26%), Positives = 60/114 (52%), Gaps = 21/114 (18%)
Query: 313 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 372
+E++ E EER +E+ ++ + E+ +K+V +E E+K+ K+E+K++E +
Sbjct: 2247 EEEEREEEEEREEEEVREEEEE------RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQ 2300
Query: 373 ESED----------KPEIEDVGSDEEEE-----KKDGDKKKKKKIKEKYIDQEE 411
E E+ + E E + +EEEE +++ D++K+ KEK +E
Sbjct: 2301 EKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQE 2354
Score = 32.0 bits (71), Expect = 2.5
Identities = 18/68 (26%), Positives = 38/68 (55%), Gaps = 2/68 (2%)
Query: 346 KERDKEVSDDEAE--EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 403
K ++++ D+E E+E E +EKE++ +E++ I++ +K +KK+ +
Sbjct: 1532 KSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQE 1591
Query: 404 EKYIDQEE 411
E+ + QEE
Sbjct: 1592 ERKLAQEE 1599
Score = 31.2 bits (69), Expect = 4.3
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
++E+ E A+E+E +EKEK + E PE E+ + E+ + K +K +E
Sbjct: 1759 QREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQK-RE 1817
Query: 405 KYIDQ-EELNKTKPI 418
++I+ EEL K K I
Sbjct: 1818 RWINSMEELTKNKMI 1832
Score = 31.2 bits (69), Expect = 4.3
Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 7/87 (8%)
Query: 360 KEDK--EEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKP 417
KE+K EEE + K SE + E+ G EEEE K++ +K KE + +K K
Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKE----AKRGDKPKE 2211
Query: 418 IWTRNPDDITNEE-YGEFYKSLTNDWE 443
++ D++ +EE + E +SL ++ E
Sbjct: 2212 KFSSQVDEVESEEHFSEEMESLLDELE 2238
Score = 30.8 bits (68), Expect = 5.6
Identities = 18/66 (27%), Positives = 40/66 (60%), Gaps = 2/66 (3%)
Query: 348 RDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEI--EDVGSDEEEEKKDGDKKKKKKIKEK 405
+++E++ +E + E+K++ E+EE + + ++ E+ +EEE +K+K + KEK
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790
Query: 406 YIDQEE 411
++EE
Sbjct: 1791 MPEEEE 1796
>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
Length = 1646
Score = 58.5 bits (140), Expect = 2e-08
Identities = 65/263 (24%), Positives = 125/263 (47%), Gaps = 27/263 (10%)
Query: 298 TGEPMGRGTKVILHLKEDQTEY-----LEERRIKEIVKKHSQFIGYPITLFVEKERDKEV 352
T E +G+ K LH K D+++ LEE +++ + + EK+ + E
Sbjct: 849 TEEVLGQQKKSPLHAKMDESKEGSIQGLEEMQVEREGSLNPSLNEENVKGQGEKKEESEE 908
Query: 353 SDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEE- 411
D++ EE+E+++ E+EKEEKE++++ E VG EEE+K++G ++E Y + E
Sbjct: 909 EDEKEEEEEEEKLEEEKEEKEAQEEQESLSVG--EEEDKEEG-------LEEIYYEDMES 959
Query: 412 ----LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQ--LEFRALLFV 465
T ++ ++ + + F ND ++ ++ + LE + LF
Sbjct: 960 FTISSGNTYFVFVPLEEEHCRKSHSTFSAMFINDTSSAKFIEQVTIPSRLILEIKKQLFS 1019
Query: 466 P--RRAPFDLFE--NRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDS-EDLPLNI 520
+P ++ +R +K ++ + IM N E+L EYL+ V++ E N+
Sbjct: 1020 EGGNFSPKEINSLCSRLEKEAARIELVESVIMLNMEKLENEYLDQANDVINKFESKFHNL 1079
Query: 521 SREMLQQSKILKVIRKNLVK-KC 542
S +++ KI +++ VK KC
Sbjct: 1080 SVDLIFIEKIQRLLTNLQVKIKC 1102
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 56.6 bits (135), Expect = 9e-08
Identities = 37/111 (33%), Positives = 62/111 (55%), Gaps = 17/111 (15%)
Query: 315 DQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEE-------- 366
++TE EE KE +K + KE++K+ E E++++KEEE
Sbjct: 14 EETEETEEEEEKEGKRKEKR-------KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66
Query: 367 -KEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTK 416
K+KEE+E E++ E E+ EEEEK++G ++KKKK + + ++EE K +
Sbjct: 67 KKKKEEEEREEEEE-EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116
Score = 48.5 bits (114), Expect = 3e-05
Identities = 28/74 (37%), Positives = 44/74 (59%), Gaps = 7/74 (9%)
Query: 345 EKERDKEVSDDEAEEKEDKE-------EEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKK 397
+KE ++ +E EE+E+KE +EK KE+++ + E E EEEEKK K+
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66
Query: 398 KKKKIKEKYIDQEE 411
KKKK +E+ ++EE
Sbjct: 67 KKKKEEEEREEEEE 80
Score = 47.8 bits (112), Expect = 4e-05
Identities = 26/93 (27%), Positives = 56/93 (60%), Gaps = 11/93 (11%)
Query: 313 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 372
K+ +T+ E+R+ KE +K + ++R K+ ++E EE+E++EEE+++EE+
Sbjct: 42 KKKKTKETEKRKEKEEEEKKRK-----------RKRKKKKEEEEREEEEEEEEEEKEEEE 90
Query: 373 ESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 405
+ E + + +EE+++ KK+++K K+K
Sbjct: 91 KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 45.8 bits (107), Expect = 2e-04
Identities = 24/74 (32%), Positives = 46/74 (62%), Gaps = 8/74 (10%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKE--------EKESEDKPEIEDVGSDEEEEKKDGDK 396
+K++ K+ +E EE E+ EEE+EKE EK E + + + +++ +EK++ +K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 397 KKKKKIKEKYIDQE 410
K+K+K K+K ++E
Sbjct: 61 KRKRKRKKKKEEEE 74
Score = 43.9 bits (102), Expect = 6e-04
Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 7/69 (10%)
Query: 348 RDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYI 407
+ K+ E EE E+ EE +E+EEKE + K + +E++K+ +KKKK K EK
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK-------RKEKRKEKEKKKKTKETEKRK 53
Query: 408 DQEELNKTK 416
++EE K +
Sbjct: 54 EKEEEEKKR 62
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 55.8 bits (133), Expect = 2e-07
Identities = 84/400 (21%), Positives = 171/400 (42%), Gaps = 66/400 (16%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEK-KDGDKKKKKKIK 403
E+ER++ + E E + +KE+E+E+E+++ ++ + D D+E+ K DG KK+ + IK
Sbjct: 568 ERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIK 627
Query: 404 EKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALL 463
+ I+ ++ +++ D Y+S + D + + + + E L
Sbjct: 628 QLKIELKKAQESQKEMKLLLD---------MYRSAPKEQRDKVQLMAAEKKSKAELEDL- 677
Query: 464 FVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISRE 523
R+ DL E+++KK N K+ E EYL + E+
Sbjct: 678 ---RQRLKDL-EDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQEE------EA 727
Query: 524 MLQQSKILKVIRKNLVKKCLELFTELAE-DKENYKKFYEQFSKNIKLGIHEDSQNRKKLS 582
+L + + +++ ++ + L +L E D N+K E+ N ++
Sbjct: 728 LLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSN-------------QIH 774
Query: 583 ELLRYYTSASGDEMVSLKD------YCTRMKENQKHIYYI---TGETKDQVANSAFVERL 633
+LL+ D++++LK R E ++H+ TGE K+ + +E
Sbjct: 775 KLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGE-KELGLRTQALEMN 833
Query: 634 RKHGLEVIYMIEPID---EYCVQQLKEFEGKTLV-SVTKEG-----LELPEDEEEKKKQE 684
++ +E + + + E ++L +F+ + + SVTKE ED +++
Sbjct: 834 KRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDMFNFKRAQEDISRLRRKL 893
Query: 685 EKKTKFENLCK----IMKDILEKKVEKVVVSNRLVTSPCC 720
E K +N+ K +M++I + K +T PCC
Sbjct: 894 ETTKKPDNVPKCDEILMEEIKDYKAR--------LTCPCC 925
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 55.5 bits (132), Expect = 2e-07
Identities = 30/63 (47%), Positives = 49/63 (77%), Gaps = 5/63 (7%)
Query: 349 DKEVSDDEAE-EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYI 407
++EV ++E E E+E+KEEEKE++E+E E + E E+ DEEEE+K+G K +++K++E+ I
Sbjct: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEE---DEEEEEKEGKKMEEEKVEEE-I 175
Query: 408 DQE 410
D E
Sbjct: 176 DTE 178
Score = 43.9 bits (102), Expect = 6e-04
Identities = 22/64 (34%), Positives = 47/64 (73%), Gaps = 5/64 (7%)
Query: 358 EEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKK--KKIKEKYIDQE---EL 412
EE+ ++EEE+ +EE++ E+K E E+ EEE+++D ++++K KK++E+ +++E E+
Sbjct: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEI 179
Query: 413 NKTK 416
+T+
Sbjct: 180 QRTQ 183
Score = 37.4 bits (85), Expect = 0.060
Identities = 20/58 (34%), Positives = 39/58 (67%), Gaps = 3/58 (5%)
Query: 357 AEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNK 414
AEE ++ +EE+ E++ E+E+ +E+EE+K+ D+++++K +EK D+EE K
Sbjct: 107 AEECSAQQGLPVEEEEVEEEEEEVEE---EEKEEEKEEDEEEEEKEEEKEEDEEEEEK 161
Score = 31.6 bits (70), Expect = 3.3
Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 5/64 (7%)
Query: 646 PIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKV 705
P++E V++ +E V ++ E EDEEE++K+EEK+ E K K + E+KV
Sbjct: 117 PVEEEEVEEEEEE-----VEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV 171
Query: 706 EKVV 709
E+ +
Sbjct: 172 EEEI 175
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 55.5 bits (132), Expect = 2e-07
Identities = 30/99 (30%), Positives = 60/99 (60%), Gaps = 7/99 (7%)
Query: 346 KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 405
++ D+ +DE +E+ D+EEE+E EE++ +D + EDV +EEEE+++ +++++++ ++
Sbjct: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENED- 170
Query: 406 YIDQEELNKTKPIWTRNPDDITNEEYGEF----YKSLTN 440
Q + T+ + DD N+EY + KSL N
Sbjct: 171 --HQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLN 207
Score = 49.3 bits (116), Expect = 2e-05
Identities = 29/93 (31%), Positives = 51/93 (54%), Gaps = 7/93 (7%)
Query: 353 SDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEEL 412
S DE ++ + E+ EKEE E E+ E D DE+EE ++GD++++++I+E+ D +E
Sbjct: 86 SVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDED 145
Query: 413 NKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDH 445
+ + +D EE E + + EDH
Sbjct: 146 GE-------DVEDEEEEEEEEEEEEEEEENEDH 171
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 52.0 bits (123), Expect = 2e-06
Identities = 22/48 (45%), Positives = 38/48 (79%)
Query: 346 KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKD 393
+E D+E ++E EE+ED+EEE+E+EE+E E++ E E+ +EEEE+++
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Score = 49.3 bits (116), Expect = 2e-05
Identities = 21/62 (33%), Positives = 45/62 (72%)
Query: 354 DDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELN 413
+++ EE+E++EEE+E EE+E E++ E E+ +EEEE+++ +++++++ I QE+ +
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTS 318
Query: 414 KT 415
T
Sbjct: 319 HT 320
Score = 48.9 bits (115), Expect = 2e-05
Identities = 20/49 (40%), Positives = 39/49 (79%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKD 393
E+E ++E ++E EE++++EEE+E+EE+E E++ E E+ +EEEE+++
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 44.3 bits (103), Expect = 5e-04
Identities = 19/60 (31%), Positives = 44/60 (73%)
Query: 346 KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 405
+E K+ EE++++EEE+E+EE+E E++ E E+ +EEEE+++ +++++++ +E+
Sbjct: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Score = 43.9 bits (102), Expect = 6e-04
Identities = 32/138 (23%), Positives = 70/138 (50%), Gaps = 10/138 (7%)
Query: 290 GSFTVRTDTGEPMGRGTKV---ILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEK 346
G T E +G+ K I+HL ++ E ++ + + + + E+
Sbjct: 172 GQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTER 231
Query: 347 ERD--KEVSDDEAEEKEDKEE-----EKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKK 399
+D + +D A E+ K++ E+E EE+E E++ E ED +EEEE+++ +++++
Sbjct: 232 SQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291
Query: 400 KKIKEKYIDQEELNKTKP 417
++ +E+ ++EE + P
Sbjct: 292 EEEEEEEEEEEEEEEAAP 309
Score = 42.7 bits (99), Expect = 0.001
Identities = 19/60 (31%), Positives = 39/60 (65%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
E+E +++ ++E EE+E++EEE+E+EE+E E++ E E+ + + ++D +K E
Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327
Score = 37.4 bits (85), Expect = 0.060
Identities = 20/90 (22%), Positives = 50/90 (55%), Gaps = 3/90 (3%)
Query: 344 VEKERDKEVSDDEAEEKEDKEEEKEK---EEKESEDKPEIEDVGSDEEEEKKDGDKKKKK 400
V ER +++ E+ +E K+K +E +++ E E+ +E+EE+++ ++++++
Sbjct: 227 VTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEE 286
Query: 401 KIKEKYIDQEELNKTKPIWTRNPDDITNEE 430
+ +E+ ++EE + + PD I E+
Sbjct: 287 EEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 51.6 bits (122), Expect = 3e-06
Identities = 90/392 (22%), Positives = 161/392 (41%), Gaps = 69/392 (17%)
Query: 309 ILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS-DDEAEEKEDKEEEK 367
IL KE+Q + +K K+H + + T+ KER + ++ E EE E +E E
Sbjct: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAEL 601
Query: 368 EKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDIT 427
+K K E++ E ++E ++ ++ KKK ++E+ E++ KT+ + + DI
Sbjct: 602 QKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERL---EQIKKTE-LGAKAFKDID 657
Query: 428 NEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLY- 486
E+ E D + +A + +E + + + D FE K+ I L
Sbjct: 658 IEDLEEL------DPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIK 711
Query: 487 ----VRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKC 542
+R+ MD E+ E I+ L++ K L+ KN + +
Sbjct: 712 SAYEEQRIKDMDLWEQQEEE----------------RITTMQLEREKALE--HKNRMSRM 753
Query: 543 LE---LFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSL 599
LE LF + K + YE+ K + + E+ NR L
Sbjct: 754 LEDRDLF--VMRLKAARQSVYEEKLKQFEERLAEERHNR--------------------L 791
Query: 600 KDYCTRMKENQKHIYYITGETKDQ--VANSAFVERLRKHGLEVIYMIEPIDEY--CVQQL 655
++ + KE ++ YY E ++Q ER + E E + EY V++L
Sbjct: 792 EERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKL 851
Query: 656 KEFEGKTLVSVTKEGLELPEDEEEKKKQEEKK 687
+E E K K EL +E E++++EE++
Sbjct: 852 EEVERK------KRQRELEIEERERRREEERR 877
Score = 33.9 bits (76), Expect = 0.66
Identities = 33/134 (24%), Positives = 59/134 (44%), Gaps = 26/134 (19%)
Query: 312 LKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERD----------KEVSDDEAEEKE 361
LK+ + EER + +K + IT + EKE + KE + E E+
Sbjct: 776 LKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERA 835
Query: 362 DKEEE-----------KEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQE 410
+EEE +E E K+ + + EIE+ EEE++ GD +K ++ D++
Sbjct: 836 KREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRK-DSRWGDRD 894
Query: 411 ELNKTKPIWTRNPD 424
++ W + P+
Sbjct: 895 ----SEGTWRKGPE 904
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 51.2 bits (121), Expect = 4e-06
Identities = 32/100 (32%), Positives = 54/100 (54%), Gaps = 13/100 (13%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
EKE ++ ++E ++KE+KEEE+E+E K+ E++ EI + ++EE E KD +
Sbjct: 375 EKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRN-KNEEEGESKDEE--------- 424
Query: 405 KYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWED 444
D++E KP D T E YGE + ++ +D
Sbjct: 425 ---DEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQD 461
Score = 41.2 bits (95), Expect = 0.004
Identities = 28/90 (31%), Positives = 48/90 (53%), Gaps = 9/90 (10%)
Query: 349 DKEVSDDEAEEKEDKEEEKEKEEKESEDKPEI-----EDVGSDEEEEKKDGDKKKKKKIK 403
++E S+DE ED+++E + S+D+ + +++ EEEE K ++ KKK+ K
Sbjct: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
Query: 404 EKYIDQEELNKTKPIWTRNPDDITNEEYGE 433
E+ ++E K + RN NEE GE
Sbjct: 394 EEEEEEEMKQKEEEEEIRN----KNEEEGE 419
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 49.7 bits (117), Expect = 1e-05
Identities = 30/101 (29%), Positives = 53/101 (52%), Gaps = 1/101 (0%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKE-EKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 403
E+ER +E +E +E+E K+EE+EKE E++ K E + VG EEE K+ K++KK+ +
Sbjct: 132 ERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER 191
Query: 404 EKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWED 444
+ ++E + + + E E K +W +
Sbjct: 192 NRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWRE 232
Score = 45.1 bits (105), Expect = 3e-04
Identities = 25/78 (32%), Positives = 47/78 (60%), Gaps = 4/78 (5%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKE----SEDKPEIEDVGSDEEEEKKDGDKKKKK 400
E+ER K + E +E E+KE+ K+KE+KE S++ E E + EE+K+ ++KK++
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
Query: 401 KIKEKYIDQEELNKTKPI 418
+ KE+ + + + K +
Sbjct: 154 REKERERKERKKRERKQV 171
Score = 44.3 bits (103), Expect = 5e-04
Identities = 30/106 (28%), Positives = 60/106 (56%), Gaps = 2/106 (1%)
Query: 313 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 372
KE ++E +ERR +E K+ + EK+ +++ + E +++ ++E KE EEK
Sbjct: 53 KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK 112
Query: 373 ESEDKPEIEDVG--SDEEEEKKDGDKKKKKKIKEKYIDQEELNKTK 416
E K E ++ G S E +E++ +++K+++ KE+ +EE K +
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
Score = 43.5 bits (101), Expect = 8e-04
Identities = 31/104 (29%), Positives = 54/104 (51%), Gaps = 19/104 (18%)
Query: 313 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSD-----DEAEEKEDKEEEK 367
K+++ E + RR KE + + EK + KE + E +E+E KEE K
Sbjct: 91 KKEERERKKRRREKENKEGEEK----------EKRKKKEKKERGRTSKEGKERERKEERK 140
Query: 368 EKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEE 411
+E KE E K E ++E E+K+ K+++K++ EK +++E
Sbjct: 141 REERKERERKKE----EREKERERKERKKRERKQVGEKEEERKE 180
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/64 (35%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Query: 345 EKER---DKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKK 401
+KER KE + E +E+ +EE KE+E K+ E + E E + E K+ G+K++++K
Sbjct: 120 KKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERK 179
Query: 402 IKEK 405
KE+
Sbjct: 180 EKER 183
Score = 41.2 bits (95), Expect = 0.004
Identities = 25/104 (24%), Positives = 55/104 (52%), Gaps = 9/104 (8%)
Query: 313 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 372
K+++ E +ER KE K+ + +G EKE +++ + + +K ++ ++ K+E+
Sbjct: 150 KKEERE--KERERKERKKRERKQVG-------EKEEERKEKERKERKKRERNRKERKKER 200
Query: 373 ESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTK 416
E +++ E + +EE KK+ K ++ +EK + E + K
Sbjct: 201 ERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 40.0 bits (92), Expect = 0.009
Identities = 20/73 (27%), Positives = 39/73 (53%)
Query: 344 VEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 403
+E ++ + + +KE +E EK K E+E E K E E +K++ ++KK+++ K
Sbjct: 45 IETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREK 104
Query: 404 EKYIDQEELNKTK 416
E +E+ + K
Sbjct: 105 ENKEGEEKEKRKK 117
Score = 39.3 bits (90), Expect = 0.016
Identities = 21/73 (28%), Positives = 44/73 (60%), Gaps = 1/73 (1%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEK-EKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 403
++ER+++ E E KE +E+EK +K+EK+ + E + +EE+K ++K++++ K
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Query: 404 EKYIDQEELNKTK 416
E+ + E + K
Sbjct: 152 EEREKERERKERK 164
Score = 36.2 bits (82), Expect = 0.13
Identities = 21/73 (28%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
E E KE + E++ + E+EK ++E E + + E +++ E+K ++++KK+ +E
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103
Query: 405 KYIDQ-EELNKTK 416
K + EE K K
Sbjct: 104 KENKEGEEKEKRK 116
Score = 35.4 bits (80), Expect = 0.23
Identities = 19/66 (28%), Positives = 37/66 (56%)
Query: 351 EVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQE 410
E+ + E E + KE +KE+E + +++ E E + E+E+K KK+KK + K ++E
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Query: 411 ELNKTK 416
+ +
Sbjct: 97 RKKRRR 102
Score = 32.3 bits (72), Expect = 1.9
Identities = 18/80 (22%), Positives = 42/80 (52%), Gaps = 10/80 (12%)
Query: 321 EERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEI 380
EER+ KE ++ + E+ R + + E +E+ ++++E++K+E+ +++ +
Sbjct: 176 EERKEKERKERKKR----------ERNRKERKKERERKERRERKKERKKKEERKKERQKD 225
Query: 381 EDVGSDEEEEKKDGDKKKKK 400
E+E K K++KK
Sbjct: 226 RQTNWREKERGKRERKERKK 245
Score = 32.0 bits (71), Expect = 2.5
Identities = 18/64 (28%), Positives = 35/64 (54%)
Query: 353 SDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEEL 412
S+ E+E + ++ K+E+ESE K E + + E +K+ +++ KK K+ +EE
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER 95
Query: 413 NKTK 416
+ K
Sbjct: 96 ERKK 99
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 49.7 bits (117), Expect = 1e-05
Identities = 36/116 (31%), Positives = 60/116 (51%), Gaps = 16/116 (13%)
Query: 300 EPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEE 359
E G G K + +E + EE+ KE + H +KER++E+ + EE
Sbjct: 687 ERPGEGEKELAEKEEWKKRDGEEQEQKEREQGH------------QKERNQEMEEGGEEE 734
Query: 360 KEDKEEEK----EKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEE 411
+ EEE+ E+EEKE E K E E + E EK++G++KK+++ ++ +EE
Sbjct: 735 HGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790
Score = 43.9 bits (102), Expect = 6e-04
Identities = 24/66 (36%), Positives = 40/66 (60%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
E+E ++E + E EE E +EEE E EE+E E K E E + EEE ++G+ + +++ E
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 405 KYIDQE 410
++E
Sbjct: 885 GEGEEE 890
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/103 (27%), Positives = 57/103 (55%), Gaps = 8/103 (7%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKE---KEEKESEDKPEIEDV-----GSDEEEEKKDGDK 396
E E ++E ++E EE+ + EEE E +EE+E E + E+E G +EE E++ ++
Sbjct: 987 EGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEER 1046
Query: 397 KKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLT 439
+K+ + +E ++EE + + + ++ + GE YK ++
Sbjct: 1047 EKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVS 1089
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/92 (28%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
E+ +E + E EE+E+ E E E E +E E + E E+ + EE +K+G+ ++ ++ +E
Sbjct: 1001 EEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNRE 1060
Query: 405 KYIDQEELNKTKPIWTRNPDDITNEEYGEFYK 436
+ ++EE K + + EEY + K
Sbjct: 1061 E--EEEEEGKYQETGEEENERQDGEEYKKVSK 1090
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/63 (36%), Positives = 41/63 (65%), Gaps = 5/63 (7%)
Query: 345 EKERDKEVSDDEAEEKEDK---EEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDK-KKKK 400
E E ++E ++E EE+E + EE + E+E E++ + ++ G +EE E++DG++ KK
Sbjct: 1031 EGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETG-EEENERQDGEEYKKVS 1089
Query: 401 KIK 403
KIK
Sbjct: 1090 KIK 1092
Score = 39.7 bits (91), Expect = 0.012
Identities = 27/75 (36%), Positives = 44/75 (58%), Gaps = 2/75 (2%)
Query: 345 EKERDKEVSDDEAE-EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 403
E E + EV +E E E E++E E+E EE+E E + E E+ + EEEE+++G ++ + +
Sbjct: 1018 EGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGE-ENRRNREEEEEEEGKYQETGEEE 1076
Query: 404 EKYIDQEELNKTKPI 418
+ D EE K I
Sbjct: 1077 NERQDGEEYKKVSKI 1091
Score = 38.1 bits (87), Expect = 0.035
Identities = 20/53 (37%), Positives = 32/53 (60%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKK 397
E E K ++E EE E +EEE E EE+E E + E + +EE E+ +G+++
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEE 870
Score = 37.7 bits (86), Expect = 0.046
Identities = 22/68 (32%), Positives = 40/68 (58%), Gaps = 3/68 (4%)
Query: 344 VEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 403
VE ER+KE + + EE+ KEE+ E+E + E + E+ EEK++G + + +++
Sbjct: 764 VEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE---EEETEGRGEEKEEGGEVEGGEVE 820
Query: 404 EKYIDQEE 411
E ++EE
Sbjct: 821 EGKGEREE 828
Score = 37.7 bits (86), Expect = 0.046
Identities = 22/67 (32%), Positives = 38/67 (56%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
EKE EV E EE + + EE+E+E + E++ E E+ + EEE+ +G +++ + E
Sbjct: 807 EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE 866
Query: 405 KYIDQEE 411
+ EE
Sbjct: 867 GEEEGEE 873
Score = 37.7 bits (86), Expect = 0.046
Identities = 23/68 (33%), Positives = 42/68 (61%), Gaps = 1/68 (1%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKE-EKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 403
E E + E + E EE+E + E +E+E E+E E++ E E+ G E EE+++G+ + + + +
Sbjct: 969 EGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGE 1028
Query: 404 EKYIDQEE 411
E + EE
Sbjct: 1029 EGEGEGEE 1036
Score = 36.6 bits (83), Expect = 0.10
Identities = 22/89 (24%), Positives = 47/89 (52%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
E++ ++E E EE+E + +EKEE + E+E+ + EEE+++G+ ++++ E
Sbjct: 784 EEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGE 843
Query: 405 KYIDQEELNKTKPIWTRNPDDITNEEYGE 433
+ + E + + ++ EE GE
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872
Score = 36.2 bits (82), Expect = 0.13
Identities = 21/66 (31%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
E E + E +E E E +EEE E E +E E + E E+ G EEE + +G+++++ +++
Sbjct: 965 EGEEEGEGEGEEGEG-EGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEG 1023
Query: 405 KYIDQE 410
+ +E
Sbjct: 1024 EVEGEE 1029
Score = 35.8 bits (81), Expect = 0.17
Identities = 37/169 (21%), Positives = 70/169 (41%), Gaps = 18/169 (10%)
Query: 271 TVITKHNDDEQYAW--ESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKE- 327
T +T+++D ++Y E G + G M + I +++ E EE+ E
Sbjct: 536 TALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAED 595
Query: 328 -----IVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIED 382
I ++ + + + ++ E+ D+ +K + E K K E+ED PE
Sbjct: 596 SKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRG 655
Query: 383 VGSDEE----------EEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTR 421
G+ EE EE++ G+K K + E+ + E+ K W +
Sbjct: 656 DGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKK 704
Score = 35.8 bits (81), Expect = 0.17
Identities = 40/172 (23%), Positives = 73/172 (42%), Gaps = 21/172 (12%)
Query: 277 NDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFI 336
+DD E S G + +V P GRG + +E R K K +
Sbjct: 627 SDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEM 686
Query: 337 GYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDV----------GSD 386
P E +KE+++ E +K D EE+++KE ++ K +++ G +
Sbjct: 687 ERP------GEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEE 740
Query: 387 EE-----EEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGE 433
EE EE+K+G+ K++ + +E ++E+ + R + EE G+
Sbjct: 741 EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGD 792
Score = 35.4 bits (80), Expect = 0.23
Identities = 20/48 (41%), Positives = 27/48 (56%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKK 392
E E + E + E E +E+ E E E+EE E E + E E G +EE E K
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGK 920
Score = 35.0 bits (79), Expect = 0.30
Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 3/66 (4%)
Query: 346 KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 405
+E + E ++E E + ++E E E EE+E E + E E G EEEE G+ K +++ +E
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE---GEGKGEEEGEEG 928
Query: 406 YIDQEE 411
+ EE
Sbjct: 929 EGEGEE 934
Score = 35.0 bits (79), Expect = 0.30
Identities = 18/51 (35%), Positives = 31/51 (60%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGD 395
E+E + E ++E E + ++E E E EE+E E K E E + E E+++G+
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938
Score = 34.7 bits (78), Expect = 0.39
Identities = 21/68 (30%), Positives = 42/68 (61%), Gaps = 2/68 (2%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEE-EEKKDGDKKKKKKIK 403
++E ++E + EE E +E E E+E++E E K E E G +E+ EE+ D + ++++ +
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKE-ERAGKEEKGEEEGDQGEGEEEETE 802
Query: 404 EKYIDQEE 411
+ ++EE
Sbjct: 803 GRGEEKEE 810
Score = 34.7 bits (78), Expect = 0.39
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 5/66 (7%)
Query: 345 EKERDKEVSDDEAEEKEDKEE----EKEKEEKESEDKPEIEDVGSDEEEE-KKDGDKKKK 399
E+E + ++E EE E +EE E E EE+E E + E E G EEEE + +G+++ +
Sbjct: 850 EEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGE 909
Query: 400 KKIKEK 405
+ +E+
Sbjct: 910 GEGEEE 915
Score = 34.7 bits (78), Expect = 0.39
Identities = 20/60 (33%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 346 KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 405
+E + E +E E E +E E E EE+E E + E E+ G +E EE+ +G+++ + + +E+
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGE-EEEGEEEGEEEGEGEEEGEGEGEEE 1016
Score = 34.3 bits (77), Expect = 0.50
Identities = 25/74 (33%), Positives = 42/74 (56%), Gaps = 7/74 (9%)
Query: 345 EKERDKEVSDDEAE-EKEDKEEEKEKEEKESEDKPEIEDVGSD------EEEEKKDGDKK 397
E+E + E D E E E+E+ E E E+EE E E + E E G + EEE + +G+++
Sbjct: 934 EEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEE 993
Query: 398 KKKKIKEKYIDQEE 411
+ ++ E+ + EE
Sbjct: 994 EGEEEGEEEGEGEE 1007
Score = 33.9 bits (76), Expect = 0.66
Identities = 20/65 (30%), Positives = 38/65 (58%)
Query: 347 ERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKY 406
E ++ + E EE+E + EE+E E +E E + E E+ EEE ++G+ +++ + E
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877
Query: 407 IDQEE 411
++EE
Sbjct: 878 GEEEE 882
Score = 33.9 bits (76), Expect = 0.66
Identities = 21/61 (34%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
E E ++E + E EE E K EE E EE E E++ E + +EEE + +G+++ + + +E
Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEE-EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE 897
Query: 405 K 405
+
Sbjct: 898 E 898
Score = 33.9 bits (76), Expect = 0.66
Identities = 18/51 (35%), Positives = 30/51 (58%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGD 395
E E + E + E E +E+ E E E+EE E + + E E+ + EEE+ +G+
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGE 940
Score = 33.1 bits (74), Expect = 1.1
Identities = 20/59 (33%), Positives = 37/59 (62%), Gaps = 4/59 (6%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKE---EKESEDKPEIEDVGSDEEEEKKDGDKKKKK 400
E+E ++ ++E EE E + EE+E E E+E E + E E+ G E EE+ +G+ ++++
Sbjct: 859 EEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE-EEEGEGEGEEEGEGEGEEEE 916
Score = 33.1 bits (74), Expect = 1.1
Identities = 20/66 (30%), Positives = 37/66 (56%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
E+E + +D E E++E E E EE+E E + E E G EE E + +++ + + +E
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992
Query: 405 KYIDQE 410
+ ++E
Sbjct: 993 EEGEEE 998
Score = 32.7 bits (73), Expect = 1.5
Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 1/68 (1%)
Query: 345 EKERDKEVSDDEAEEK-EDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIK 403
E E ++E + E EE+ E + EE+E E K E+ E E G +EE E + D + + + +
Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE 951
Query: 404 EKYIDQEE 411
E + EE
Sbjct: 952 EGEWEGEE 959
Score = 31.2 bits (69), Expect = 4.3
Identities = 21/52 (40%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Query: 346 KERDKEVSDDEAE-EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDK 396
+E + E ++E E E ED E E E+EE E E + E E G EEE + +G++
Sbjct: 926 EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE-EGEGEGEEEGEGEGEE 976
Score = 30.8 bits (68), Expect = 5.6
Identities = 20/64 (31%), Positives = 38/64 (59%), Gaps = 3/64 (4%)
Query: 345 EKERDKEVSDDEAEEKEDK---EEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKK 401
E E ++E + E EE+E + EEE E E +E E + E E+ + EEE+ + + +++ +
Sbjct: 945 EGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE 1004
Query: 402 IKEK 405
+E+
Sbjct: 1005 GEEE 1008
Score = 30.4 bits (67), Expect = 7.3
Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 2/57 (3%)
Query: 345 EKERDKEVSDDEAEEKEDK--EEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKK 399
E+E + ++E EE E + EEE E E ++ E + E E+ + EEE+ +G+ +++
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEE 969
>gi|4757900 calreticulin precursor [Homo sapiens]
Length = 417
Score = 48.5 bits (114), Expect = 3e-05
Identities = 26/59 (44%), Positives = 41/59 (69%), Gaps = 4/59 (6%)
Query: 344 VEKERDKEVSDDEAEE---KEDKEEEKEKEEKESEDKPEIEDVGSDEE-EEKKDGDKKK 398
V K +K++ D + EE KE++E++K KEE+E+EDK + ED DEE EE K+ D+++
Sbjct: 349 VTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEE 407
Score = 42.0 bits (97), Expect = 0.002
Identities = 18/46 (39%), Positives = 32/46 (69%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEE 390
E++R KE +D+ ++E++ E+KE +E + ED+ + ED DEEE+
Sbjct: 363 EEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408
Score = 38.9 bits (89), Expect = 0.020
Identities = 17/48 (35%), Positives = 30/48 (62%)
Query: 346 KERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKD 393
KE +++ E EE EDKE++++K+E E +++ + ED D + KD
Sbjct: 368 KEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKD 415
Score = 37.4 bits (85), Expect = 0.060
Identities = 19/58 (32%), Positives = 34/58 (58%), Gaps = 10/58 (17%)
Query: 321 EERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKP 378
EE+R+KE + + ++E + E +D+ ++ ED+E+E++KEE E ED P
Sbjct: 363 EEQRLKEEEEDKKR----------KEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVP 410
Score = 35.8 bits (81), Expect = 0.17
Identities = 15/54 (27%), Positives = 39/54 (72%), Gaps = 1/54 (1%)
Query: 358 EEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEE 411
++ +DK++E+++ ++E EDK E+ ++++E+ +D D+ ++ + ++K D+EE
Sbjct: 355 KQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDE-EDKEEDEEE 407
Score = 35.4 bits (80), Expect = 0.23
Identities = 16/47 (34%), Positives = 30/47 (63%), Gaps = 4/47 (8%)
Query: 345 EKERDKEVSDDEAEEKEDKEE----EKEKEEKESEDKPEIEDVGSDE 387
E+E K ++EAE+KED E+ E+++E+KE +++ ++ DE
Sbjct: 370 EEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
Score = 31.2 bits (69), Expect = 4.3
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Query: 360 KEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKD-GDKKKKKKIKEKYIDQEE 411
K +++ K+K+++E K E ED EEEE +D D + K + +E D+EE
Sbjct: 351 KAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEE 403
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 48.5 bits (114), Expect = 3e-05
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 4/87 (4%)
Query: 313 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 372
K D ++Y E R+ V++ +G+ L + +A KE++EEE+E EE+
Sbjct: 689 KRDLSDYRERARLLNRVRR----VGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEE 744
Query: 373 ESEDKPEIEDVGSDEEEEKKDGDKKKK 399
E ED+ E E+ +EEEE+++ +++++
Sbjct: 745 EEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 41.2 bits (95), Expect = 0.004
Identities = 16/41 (39%), Positives = 32/41 (78%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGS 385
E+E ++E ++E E++E++EEE+E+EE+E E++ E E+ +
Sbjct: 734 EEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAA 774
Score = 40.4 bits (93), Expect = 0.007
Identities = 19/54 (35%), Positives = 33/54 (61%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKK 398
E+E ++E +DE EE+E++EEE+E+EE+E E++ V E + G +
Sbjct: 738 EEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSE 791
Score = 38.5 bits (88), Expect = 0.027
Identities = 19/60 (31%), Positives = 37/60 (61%), Gaps = 5/60 (8%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDV-----GSDEEEEKKDGDKKKK 399
E+E + E ++E EE+E++EEE+E+EE+E+ + +V GS E ++ D+ ++
Sbjct: 743 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQE 802
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 48.1 bits (113), Expect = 3e-05
Identities = 26/69 (37%), Positives = 46/69 (66%), Gaps = 6/69 (8%)
Query: 345 EKERDKEVSDDEAE-----EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKK 399
+K++DKE S DE E +K+ K++EK++E K DK +++ V D +EE++ D +K+
Sbjct: 379 KKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDK-DVKQVTRDYDEEEQGYDSEKE 437
Query: 400 KKIKEKYID 408
KK ++K I+
Sbjct: 438 KKEEKKPIE 446
Score = 36.6 bits (83), Expect = 0.10
Identities = 18/74 (24%), Positives = 39/74 (52%), Gaps = 8/74 (10%)
Query: 358 EEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEE------ 411
E+K+DK++E+ ++E+E + + +++ E+K K K++ Y ++E+
Sbjct: 377 EKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEK 436
Query: 412 --LNKTKPIWTRNP 423
+ KPI T +P
Sbjct: 437 EKKEEKKPIETGSP 450
Score = 31.2 bits (69), Expect = 4.3
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 14/83 (16%)
Query: 350 KEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQ 409
+++S + + KE++K+K+++ S D E ++ KKKK K KEK D+
Sbjct: 363 RKLSRSPSPRRHKKEKKKDKDKERSRD------------ERERSTSKKKKSKDKEK--DR 408
Query: 410 EELNKTKPIWTRNPDDITNEEYG 432
E +++ + D EE G
Sbjct: 409 ERKSESDKDVKQVTRDYDEEEQG 431
>gi|4758220 XAP-5 protein [Homo sapiens]
Length = 339
Score = 47.8 bits (112), Expect = 4e-05
Identities = 29/107 (27%), Positives = 60/107 (56%), Gaps = 9/107 (8%)
Query: 346 KERDKEVSDDE-AEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
KER+K+++ E ++E + K E+ ++E++ E K +I + EEE++ G+++++ + E
Sbjct: 82 KEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSLSFTLEEEEEGGEEEEEAAMYE 141
Query: 405 KYIDQEELNKTKPIWTRNPDDITN--------EEYGEFYKSLTNDWE 443
+ +++EE+ K +NPD T+ EE + L +WE
Sbjct: 142 EEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWE 188
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 47.4 bits (111), Expect = 6e-05
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 33/161 (20%)
Query: 347 ERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEK--------KDGDKKK 398
+ D E SD+E EE+E++EEE+ + +E ED ++++ D+EEE KDGDK
Sbjct: 437 DEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSP 496
Query: 399 KKKIK---EKYIDQ---------EELNKTKPIWTR-------NPDDITNEEYGEFYKSLT 439
++ EK ++ E+ NK + + P I E GE + LT
Sbjct: 497 MSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELT 556
Query: 440 NDWEDHLAVKHFSVEGQLEFRAL-LFVPRRAPFDLFENRKK 479
+ E + S +LE AL L P D+ +RK+
Sbjct: 557 LEEESPV-----SQLFELEIEALPLDTPSSVETDISSSRKQ 592
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 47.4 bits (111), Expect = 6e-05
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 33/161 (20%)
Query: 347 ERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEK--------KDGDKKK 398
+ D E SD+E EE+E++EEE+ + +E ED ++++ D+EEE KDGDK
Sbjct: 437 DEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSP 496
Query: 399 KKKIK---EKYIDQ---------EELNKTKPIWTR-------NPDDITNEEYGEFYKSLT 439
++ EK ++ E+ NK + + P I E GE + LT
Sbjct: 497 MSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELT 556
Query: 440 NDWEDHLAVKHFSVEGQLEFRAL-LFVPRRAPFDLFENRKK 479
+ E + S +LE AL L P D+ +RK+
Sbjct: 557 LEEESPV-----SQLFELEIEALPLDTPSSVETDISSSRKQ 592
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 47.4 bits (111), Expect = 6e-05
Identities = 46/161 (28%), Positives = 73/161 (45%), Gaps = 33/161 (20%)
Query: 347 ERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEK--------KDGDKKK 398
+ D E SD+E EE+E++EEE+ + +E ED ++++ D+EEE KDGDK
Sbjct: 449 DEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSP 508
Query: 399 KKKIK---EKYIDQ---------EELNKTKPIWTR-------NPDDITNEEYGEFYKSLT 439
++ EK ++ E+ NK + + P I E GE + LT
Sbjct: 509 MSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELT 568
Query: 440 NDWEDHLAVKHFSVEGQLEFRAL-LFVPRRAPFDLFENRKK 479
+ E + S +LE AL L P D+ +RK+
Sbjct: 569 LEEESPV-----SQLFELEIEALPLDTPSSVETDISSSRKQ 604
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 47.4 bits (111), Expect = 6e-05
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 4/119 (3%)
Query: 308 VILHLKEDQTEYLE--ERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEE 365
V H+K E ++ E+ KE V Q +T V +E +KE ++E +E+E EE
Sbjct: 432 VSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEE 491
Query: 366 EKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPD 424
E+ + +E P E+ S E+E K ++ K + K ++EE P ++P+
Sbjct: 492 EEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAK--SPAEVKSPE 548
Score = 40.0 bits (92), Expect = 0.009
Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Query: 344 VEK-ERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKI 402
VEK E++ + +++ EE + EE E+EEKE++++ E+ G +EEE + ++ K
Sbjct: 447 VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPA 506
Query: 403 KEKYIDQEELNKTKPIWTRNPDDITNEEYGE 433
+E ++E ++P + + E E
Sbjct: 507 EEAASPEKEAKSPVKEEAKSPAEAKSPEKEE 537
Score = 34.7 bits (78), Expect = 0.39
Identities = 35/134 (26%), Positives = 58/134 (43%), Gaps = 5/134 (3%)
Query: 312 LKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEA----EEKEDKEEEK 367
LKED +E KE VK + P + V KE K+ +++A + +E K+ +K
Sbjct: 803 LKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKV-KEPPKKAEEEKAPATPKTEEKKDSKK 861
Query: 368 EKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDIT 427
E+ K+ KP++E+ E+ K+ + KK+ E K P +D
Sbjct: 862 EEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK 921
Query: 428 NEEYGEFYKSLTND 441
+E E K +D
Sbjct: 922 PKEKTEVAKKEPDD 935
Score = 34.3 bits (77), Expect = 0.50
Identities = 25/115 (21%), Positives = 51/115 (44%)
Query: 316 QTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESE 375
+ E +E ++KE KK + EK+ K+ + E + K EEK++ E
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885
Query: 376 DKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEE 430
+ ++E + E++KK +K+ K + + + + + + PDD +E
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940
Score = 32.3 bits (72), Expect = 1.9
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 5/77 (6%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPE---IEDVGSDEEEEKKDGDKK--KK 399
EK + D +A EKE ++E+ K + E+KP+ +++ EEEK K +K
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK 856
Query: 400 KKIKEKYIDQEELNKTK 416
K K++ ++E K K
Sbjct: 857 KDSKKEEAPKKEAPKPK 873
Score = 32.3 bits (72), Expect = 1.9
Identities = 21/90 (23%), Positives = 41/90 (45%)
Query: 341 TLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKK 400
T +KE D + + ++ E KE EK++ + E + E+ E + K+D K+
Sbjct: 926 TEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985
Query: 401 KIKEKYIDQEELNKTKPIWTRNPDDITNEE 430
K K E+ + T ++ P+ T ++
Sbjct: 986 PSKPKAEKAEKSSSTDQKDSKPPEKATEDK 1015
Score = 31.6 bits (70), Expect = 3.3
Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 12/85 (14%)
Query: 344 VEKERDKEVSDDEAEEKEDKEE----EKE-------KEEKESEDKPEIEDVGSDEEEEKK 392
VEK ++ +V + + EE EDK++ EKE KE+ + ++K E+ D+ + K+
Sbjct: 882 VEKPKESKV-EAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940
Query: 393 DGDKKKKKKIKEKYIDQEELNKTKP 417
+KK+ + D +E KP
Sbjct: 941 PSKPAEKKEAAPEKKDTKEEKAKKP 965
Score = 31.2 bits (69), Expect = 4.3
Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEE---EKKDGDKKKKKK 401
E ++ + EA K + +E+ + +EK K E +D + E EKK+ +KK
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT 957
Query: 402 IKEKYIDQEELNKTK 416
+EK EE KT+
Sbjct: 958 KEEKAKKPEEKPKTE 972
Score = 30.4 bits (67), Expect = 7.3
Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 6/65 (9%)
Query: 346 KERDK-EVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKE 404
K ++K EV+ E ++ + KE K E+KE+ PE +D +EE+ K ++K K + K
Sbjct: 921 KPKEKTEVAKKEPDDAKAKEPSKPAEKKEAA--PEKKDT---KEEKAKKPEEKPKTEAKA 975
Query: 405 KYIDQ 409
K D+
Sbjct: 976 KEDDK 980
Score = 30.0 bits (66), Expect = 9.5
Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 14/81 (17%)
Query: 345 EKERDKEVSDDEAEEKE------------DKEEEKEKEEKESEDKPEIEDVGSDEEE--E 390
EK + D+A+ KE +K++ KE++ K+ E+KP+ E ++++
Sbjct: 924 EKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS 983
Query: 391 KKDGDKKKKKKIKEKYIDQEE 411
K+ K +K K DQ++
Sbjct: 984 KEPSKPKAEKAEKSSSTDQKD 1004
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 47.4 bits (111), Expect = 6e-05
Identities = 24/70 (34%), Positives = 39/70 (55%)
Query: 354 DDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELN 413
+DE EE+E +EEE+E EE+E ED+ E E+ +EEEE + + +K + I
Sbjct: 361 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTG 420
Query: 414 KTKPIWTRNP 423
+ P+ + P
Sbjct: 421 EPAPVLSSPP 430
Score = 40.8 bits (94), Expect = 0.005
Identities = 23/91 (25%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 337 GYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDK 396
G+ + + D E ++E E +E++EE +E+EE++ E++ E E+ +EEE ++ G
Sbjct: 347 GFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEE--EEEEEPQQRGQG 404
Query: 397 KKKKKIKEKYIDQEELNKTKPIWTRNPDDIT 427
+K K +D + + P D++
Sbjct: 405 EKSATPSRKILDPNTGEPAPVLSSPPPADVS 435
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 47.0 bits (110), Expect = 8e-05
Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 3/77 (3%)
Query: 356 EAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK---YIDQEEL 412
E EE+E++EEE+E+EE+E E++ E E+ G+ + G +K KKK ++ +
Sbjct: 300 EEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKR 359
Query: 413 NKTKPIWTRNPDDITNE 429
K +P + P ++N+
Sbjct: 360 RKREPPRAKEPRGVSND 376
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 47.0 bits (110), Expect = 8e-05
Identities = 22/58 (37%), Positives = 44/58 (75%), Gaps = 4/58 (6%)
Query: 353 SDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQE 410
SD+E EE+E++EEE+E+EE+E ED E E ++EEE + +++++++ +E++ ++E
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEE----EDEEEYFEEEEEEEEEFEEEFEEEE 939
Score = 47.0 bits (110), Expect = 8e-05
Identities = 22/61 (36%), Positives = 45/61 (73%), Gaps = 1/61 (1%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESED-KPEIEDVGSDEEEEKKDGDKKKKKKIK 403
E+E ++E +D EE+ED+EE E+EE+E E+ + E E+ + EEE+++ D++++++++
Sbjct: 899 EEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958
Query: 404 E 404
E
Sbjct: 959 E 959
Score = 46.2 bits (108), Expect = 1e-04
Identities = 23/74 (31%), Positives = 50/74 (67%), Gaps = 2/74 (2%)
Query: 340 ITLFVEKERDKEVSDDEAEEKEDKEEEKEKE--EKESEDKPEIEDVGSDEEEEKKDGDKK 397
+T+ D+E ++E EE+E++EEE+E+E E+E ED+ E + +EEEE ++ ++
Sbjct: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEE 937
Query: 398 KKKKIKEKYIDQEE 411
++ +++E+ +++E
Sbjct: 938 EEGELEEEEEEEDE 951
Score = 45.4 bits (106), Expect = 2e-04
Identities = 23/77 (29%), Positives = 54/77 (70%), Gaps = 4/77 (5%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKESE---DKPEIEDVGSDEEEEKKDGDKKKKKK 401
E+E ++E ++E EE+E++EE+ E+EE++ E ++ E E+ +EE E+++G+ +++++
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
Query: 402 IKEKYIDQEELNKTKPI 418
+E ++EEL + + +
Sbjct: 948 -EEDEEEEEELEEVEDL 963
Score = 40.4 bits (93), Expect = 0.007
Identities = 23/50 (46%), Positives = 34/50 (68%), Gaps = 1/50 (2%)
Query: 343 FVEKERDKEVSDDEAEEKEDK-EEEKEKEEKESEDKPEIEDVGSDEEEEK 391
F E+E D+E +E EE+E++ EEE E+EE E E++ E ED +EE E+
Sbjct: 910 FEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEE 959
Score = 38.5 bits (88), Expect = 0.027
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 20/79 (25%)
Query: 313 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 372
+ED+ EY EE +E +E ++E ++E E +E++EEE E+EE+
Sbjct: 914 EEDEEEYFEEEEEEE------------------EEFEEEFEEEEGELEEEEEEEDEEEEE 955
Query: 373 ESEDKPEIE--DVGSDEEE 389
E E+ ++E G + EE
Sbjct: 956 ELEEVEDLEFGTAGGEVEE 974
Score = 37.7 bits (86), Expect = 0.046
Identities = 22/71 (30%), Positives = 43/71 (60%), Gaps = 8/71 (11%)
Query: 313 KEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEK 372
+E++ E EE +E + ++ F E+E ++E ++E EE+E + EE+E EE+
Sbjct: 898 EEEEEEEEEEEDFEEEEEDEEEY-------FEEEEEEEEEFEEEFEEEEGELEEEE-EEE 949
Query: 373 ESEDKPEIEDV 383
+ E++ E+E+V
Sbjct: 950 DEEEEEELEEV 960
Score = 36.6 bits (83), Expect = 0.10
Identities = 20/70 (28%), Positives = 41/70 (58%)
Query: 364 EEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNP 423
+EE+E+EE+E E++ E E+ D EEE++D ++ +++ +E+ +EE + +
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
Query: 424 DDITNEEYGE 433
++ EE E
Sbjct: 947 EEEDEEEEEE 956
Score = 32.7 bits (73), Expect = 1.5
Identities = 22/80 (27%), Positives = 43/80 (53%)
Query: 315 DQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKES 374
D+ E EE +E ++ + + E+E +E ++E E +E+ EEE+ + E+E
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
Query: 375 EDKPEIEDVGSDEEEEKKDG 394
E++ E E+ +E E+ + G
Sbjct: 947 EEEDEEEEEELEEVEDLEFG 966
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 47.0 bits (110), Expect = 8e-05
Identities = 33/144 (22%), Positives = 64/144 (44%), Gaps = 19/144 (13%)
Query: 273 ITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKH 332
++ + ++ ES + D P R K L+E+Q Y ++++ + I
Sbjct: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA-ELEENQRSYKQKKKRRRI---- 1390
Query: 333 SQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKK 392
+ ++ S + E++EEEKE+EE+E E++ E E+ +D+ +
Sbjct: 1391 --------------KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1436
Query: 393 DGDKKKKKKIKEKYIDQEELNKTK 416
G KK +K +K+ + E N K
Sbjct: 1437 KGRKKIRKILKDDKLRTETQNALK 1460
Score = 33.1 bits (74), Expect = 1.1
Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Query: 344 VEKERDKEVSDDEAEEKEDKEEEKEKEEKESED--KPEIEDVGSDEEEEKKDGDKKKKKK 401
V+ ++VS +++E+ + +E +E ESED +P E EE + K+KKK+
Sbjct: 1328 VKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1387
Query: 402 IKEKYIDQEELNKTKPIWTRNPDDITNEEYGE 433
+ K + ++ ++ K ++ EE E
Sbjct: 1388 RRIK-VQEDSSSENKSNSEEEEEEKEEEEEEE 1418
Score = 31.2 bits (69), Expect = 4.3
Identities = 15/65 (23%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 342 LFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKK 401
+ +E+ + SD++ ++ EE K++ K++E+ P E+ + E D D ++ KK
Sbjct: 1237 MLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSES-DSDSEESKK 1295
Query: 402 IKEKY 406
+ ++
Sbjct: 1296 PRYRH 1300
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 47.0 bits (110), Expect = 8e-05
Identities = 33/144 (22%), Positives = 64/144 (44%), Gaps = 19/144 (13%)
Query: 273 ITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKH 332
++ + ++ ES + D P R K L+E+Q Y ++++ + I
Sbjct: 1374 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA-ELEENQRSYKQKKKRRRI---- 1428
Query: 333 SQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKK 392
+ ++ S + E++EEEKE+EE+E E++ E E+ +D+ +
Sbjct: 1429 --------------KVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1474
Query: 393 DGDKKKKKKIKEKYIDQEELNKTK 416
G KK +K +K+ + E N K
Sbjct: 1475 KGRKKIRKILKDDKLRTETQNALK 1498
Score = 33.1 bits (74), Expect = 1.1
Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Query: 344 VEKERDKEVSDDEAEEKEDKEEEKEKEEKESED--KPEIEDVGSDEEEEKKDGDKKKKKK 401
V+ ++VS +++E+ + +E +E ESED +P E EE + K+KKK+
Sbjct: 1366 VKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKR 1425
Query: 402 IKEKYIDQEELNKTKPIWTRNPDDITNEEYGE 433
+ K + ++ ++ K ++ EE E
Sbjct: 1426 RRIK-VQEDSSSENKSNSEEEEEEKEEEEEEE 1456
Score = 31.2 bits (69), Expect = 4.3
Identities = 15/65 (23%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 342 LFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKK 401
+ +E+ + SD++ ++ EE K++ K++E+ P E+ + E D D ++ KK
Sbjct: 1275 MLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSES-DSDSEESKK 1333
Query: 402 IKEKY 406
+ ++
Sbjct: 1334 PRYRH 1338
>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
Length = 482
Score = 47.0 bits (110), Expect = 8e-05
Identities = 29/118 (24%), Positives = 68/118 (57%), Gaps = 12/118 (10%)
Query: 313 KEDQTEYLEERRIKE--IVKKHSQFIGYPITLFVEKERD----KEVSDDEAEEKEDKEEE 366
+E++ ++EE++++E ++++ Q + L +K ++ K+ ++ A+++++++E
Sbjct: 46 EEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQER 105
Query: 367 KEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPD 424
K KE+ E + + E EEEE+K +KK+K++ +K +DQ E +NP+
Sbjct: 106 KLKEQWEEQQRKE------REEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPE 157
Score = 33.5 bits (75), Expect = 0.86
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 4/104 (3%)
Query: 345 EKERDKEVSDDEAEEKEDKEEEKEKEEKE---SEDKPEIE-DVGSDEEEEKKDGDKKKKK 400
E+E D + + + EE++ E E+++ +E E K + E + ++EE K +++++
Sbjct: 46 EEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQER 105
Query: 401 KIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWED 444
K+KE++ +Q+ + + R E + N+ E+
Sbjct: 106 KLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELEN 149
Score = 30.8 bits (68), Expect = 5.6
Identities = 35/149 (23%), Positives = 65/149 (43%), Gaps = 16/149 (10%)
Query: 568 KLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANS 627
K+ E ++K + L + E+ L+D KE ++ + + Q+
Sbjct: 6 KMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFI----EEQQLEEE 61
Query: 628 AFVER----------LRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDE 677
+ER LR+ + + I+ E ++ +E + + L +E + E E
Sbjct: 62 KLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQ-QRKERE 120
Query: 678 EEKKKQEEKKTKFENLCKIMKDILEKKVE 706
EE++K++EKK K E L K M D E ++E
Sbjct: 121 EEEQKRQEKKEKEEALQK-MLDQAENELE 148
Score = 30.0 bits (66), Expect = 9.5
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Query: 348 RDKEVSDDEAEEKEDKEEEKEKEEK--ESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEK 405
RD +S E EE EE++ +EEK E E + E+ E++ +++ KK+K+ K
Sbjct: 38 RDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAK 97
Query: 406 YIDQEELNKTKPIWTRNPDDITNEE 430
+E+ K K W EE
Sbjct: 98 KRQEEQERKLKEQWEEQQRKEREEE 122
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,418,785
Number of Sequences: 37866
Number of extensions: 1721036
Number of successful extensions: 44504
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 727
Number of HSP's successfully gapped in prelim test: 641
Number of HSP's that attempted gapping in prelim test: 14171
Number of HSP's gapped (non-prelim): 14595
length of query: 854
length of database: 18,247,518
effective HSP length: 111
effective length of query: 743
effective length of database: 14,044,392
effective search space: 10434983256
effective search space used: 10434983256
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.