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Search of human proteins with 153792461
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]
(870 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens] 1794 0.0
gi|157502187 radial spoke head 10 homolog B [Homo sapiens] 1791 0.0
gi|13376267 MORN repeat containing 1 [Homo sapiens] 103 5e-22
gi|50355990 MORN repeat containing 3 [Homo sapiens] 100 8e-21
gi|40316935 alsin isoform 1 [Homo sapiens] 98 4e-20
gi|18254456 testis-specific gene A2 [Homo sapiens] 93 9e-19
gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens] 86 1e-16
gi|21735575 junctophilin 1 [Homo sapiens] 81 4e-15
gi|21704283 junctophilin 3 [Homo sapiens] 78 3e-14
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens] 75 3e-13
gi|225690502 junctophilin 4 [Homo sapiens] 69 1e-11
gi|225690500 junctophilin 4 [Homo sapiens] 69 1e-11
gi|149999376 MORN repeat containing 4 [Homo sapiens] 64 6e-10
gi|30520314 MORN repeat containing 4 [Homo sapiens] 64 6e-10
gi|29893812 junctophilin 2 isoform 2 [Homo sapiens] 62 2e-09
gi|75750531 ankyrin repeat and MYND domain containing 1 isoform ... 57 6e-08
gi|18139549 SET domain-containing protein 7 [Homo sapiens] 55 4e-07
gi|75750529 ankyrin repeat and MYND domain containing 1 isoform ... 50 7e-06
gi|224282170 MORN repeat containing 2 [Homo sapiens] 46 1e-04
gi|223278407 MORN repeat containing 5 [Homo sapiens] 43 0.001
gi|153945715 myosin VC [Homo sapiens] 37 0.079
gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens] 35 0.23
gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens] 35 0.23
gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens] 35 0.23
gi|37694065 estrogen receptor binding site associated antigen 9 ... 34 0.67
gi|4758230 estrogen receptor binding site associated antigen 9 [... 34 0.67
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 33 1.1
gi|155030242 WD repeat domain 60 [Homo sapiens] 33 1.5
gi|122937227 U2-associated SR140 protein [Homo sapiens] 33 1.5
gi|21264343 scaffold attachment factor B [Homo sapiens] 32 2.0
>gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]
Length = 870
Score = 1794 bits (4647), Expect = 0.0
Identities = 870/870 (100%), Positives = 870/870 (100%)
Query: 1 MVKEKKKADKKGEKSARSPSSLSDNLDFSKQDGNTTRQEMSPAGVPLLGMQLNEVKPKKD 60
MVKEKKKADKKGEKSARSPSSLSDNLDFSKQDGNTTRQEMSPAGVPLLGMQLNEVKPKKD
Sbjct: 1 MVKEKKKADKKGEKSARSPSSLSDNLDFSKQDGNTTRQEMSPAGVPLLGMQLNEVKPKKD 60
Query: 61 RQNVQQNEDASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHG 120
RQNVQQNEDASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHG
Sbjct: 61 RQNVQQNEDASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHG 120
Query: 121 QGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYI 180
QGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYI
Sbjct: 121 QGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYI 180
Query: 181 GHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEG 240
GHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEG
Sbjct: 181 GHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEG 240
Query: 241 RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFY 300
RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFY
Sbjct: 241 RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFY 300
Query: 301 YASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEVEFISCLDLSSGVA 360
YASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEVEFISCLDLSSGVA
Sbjct: 301 YASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEVEFISCLDLSSGVA 360
Query: 361 PRLSRSAELIRKLDGSESHSVLGSSIELDLNLLLDMYPETVQPEEKKQVEYAVLRNITEL 420
PRLSRSAELIRKLDGSESHSVLGSSIELDLNLLLDMYPETVQPEEKKQVEYAVLRNITEL
Sbjct: 361 PRLSRSAELIRKLDGSESHSVLGSSIELDLNLLLDMYPETVQPEEKKQVEYAVLRNITEL 420
Query: 421 RRIYSFYSSLGCGHSLDNTFLMTKLHFWRFLKDCKFHHHKLTLADMDRILSANNDIPVEE 480
RRIYSFYSSLGCGHSLDNTFLMTKLHFWRFLKDCKFHHHKLTLADMDRILSANNDIPVEE
Sbjct: 421 RRIYSFYSSLGCGHSLDNTFLMTKLHFWRFLKDCKFHHHKLTLADMDRILSANNDIPVEE 480
Query: 481 IHSPFTTILLRTFLNYLLHLAYHIYHEEFQKRSPSLFLCFTKLMTENIRPNACQIKGNLF 540
IHSPFTTILLRTFLNYLLHLAYHIYHEEFQKRSPSLFLCFTKLMTENIRPNACQIKGNLF
Sbjct: 481 IHSPFTTILLRTFLNYLLHLAYHIYHEEFQKRSPSLFLCFTKLMTENIRPNACQIKGNLF 540
Query: 541 REQQRTLYSMSYMNKCWEIYLAYCRPSAAPPHEPTMKMRHFLWMLKDFKMINKELTAATF 600
REQQRTLYSMSYMNKCWEIYLAYCRPSAAPPHEPTMKMRHFLWMLKDFKMINKELTAATF
Sbjct: 541 REQQRTLYSMSYMNKCWEIYLAYCRPSAAPPHEPTMKMRHFLWMLKDFKMINKELTAATF 600
Query: 601 MEVIAEDNRFIYDGIDSNFEPELVFLEFFEALLSFAFICVTDQMTKSYTNVPADDVSGNK 660
MEVIAEDNRFIYDGIDSNFEPELVFLEFFEALLSFAFICVTDQMTKSYTNVPADDVSGNK
Sbjct: 601 MEVIAEDNRFIYDGIDSNFEPELVFLEFFEALLSFAFICVTDQMTKSYTNVPADDVSGNK 660
Query: 661 HETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSV 720
HETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSV
Sbjct: 661 HETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSV 720
Query: 721 SHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNNTYVFFVNTLFHAYKRE 780
SHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNNTYVFFVNTLFHAYKRE
Sbjct: 721 SHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNNTYVFFVNTLFHAYKRE 780
Query: 781 EAIKEKIRADRLRSTAQAQQRKMEDDELEARLNIFILREEEAKRHDYEVDITVLKEPADV 840
EAIKEKIRADRLRSTAQAQQRKMEDDELEARLNIFILREEEAKRHDYEVDITVLKEPADV
Sbjct: 781 EAIKEKIRADRLRSTAQAQQRKMEDDELEARLNIFILREEEAKRHDYEVDITVLKEPADV 840
Query: 841 SSSHLILDPPKEDVTVSPSSKTITSKKKKK 870
SSSHLILDPPKEDVTVSPSSKTITSKKKKK
Sbjct: 841 SSSHLILDPPKEDVTVSPSSKTITSKKKKK 870
>gi|157502187 radial spoke head 10 homolog B [Homo sapiens]
Length = 870
Score = 1791 bits (4638), Expect = 0.0
Identities = 868/870 (99%), Positives = 869/870 (99%)
Query: 1 MVKEKKKADKKGEKSARSPSSLSDNLDFSKQDGNTTRQEMSPAGVPLLGMQLNEVKPKKD 60
MVKEKKKADKKGEKSARSPSSLSDNLDFSKQDGNTTRQEMSPAGVPLLGMQLNEVKPKKD
Sbjct: 1 MVKEKKKADKKGEKSARSPSSLSDNLDFSKQDGNTTRQEMSPAGVPLLGMQLNEVKPKKD 60
Query: 61 RQNVQQNEDASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHG 120
RQNVQQNEDA+QYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHG
Sbjct: 61 RQNVQQNEDATQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHG 120
Query: 121 QGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYI 180
QGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYI
Sbjct: 121 QGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYI 180
Query: 181 GHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEG 240
GHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEG
Sbjct: 181 GHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEG 240
Query: 241 RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFY 300
RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFY
Sbjct: 241 RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFY 300
Query: 301 YASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEVEFISCLDLSSGVA 360
YASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEVEFISCLDLSSGVA
Sbjct: 301 YASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEVEFISCLDLSSGVA 360
Query: 361 PRLSRSAELIRKLDGSESHSVLGSSIELDLNLLLDMYPETVQPEEKKQVEYAVLRNITEL 420
PRLSRSAELIRKLDGSESHSVLGSSIELDLNLLLDMYPETVQPEEKKQVEYAVLRNITEL
Sbjct: 361 PRLSRSAELIRKLDGSESHSVLGSSIELDLNLLLDMYPETVQPEEKKQVEYAVLRNITEL 420
Query: 421 RRIYSFYSSLGCGHSLDNTFLMTKLHFWRFLKDCKFHHHKLTLADMDRILSANNDIPVEE 480
RRIYSFYSSLGCGHSLDNTFLMTKLHFWRFLKDCKFHHHKLTLADMDRILSANNDIPVEE
Sbjct: 421 RRIYSFYSSLGCGHSLDNTFLMTKLHFWRFLKDCKFHHHKLTLADMDRILSANNDIPVEE 480
Query: 481 IHSPFTTILLRTFLNYLLHLAYHIYHEEFQKRSPSLFLCFTKLMTENIRPNACQIKGNLF 540
IHSPFTTILLRTFLNYLLHLAYHIYHEEFQKRSPSLFLCFTKLMTENIRPNACQIKGNLF
Sbjct: 481 IHSPFTTILLRTFLNYLLHLAYHIYHEEFQKRSPSLFLCFTKLMTENIRPNACQIKGNLF 540
Query: 541 REQQRTLYSMSYMNKCWEIYLAYCRPSAAPPHEPTMKMRHFLWMLKDFKMINKELTAATF 600
REQQRTLYSMSYMNKCWEIYLAYCRPSAAPPHEPTMKMRHFLWMLKDFKMINKELTAATF
Sbjct: 541 REQQRTLYSMSYMNKCWEIYLAYCRPSAAPPHEPTMKMRHFLWMLKDFKMINKELTAATF 600
Query: 601 MEVIAEDNRFIYDGIDSNFEPELVFLEFFEALLSFAFICVTDQMTKSYTNVPADDVSGNK 660
MEVIAEDNRFIYDGIDSNFEPELVFLEFFEALLSFAFICVTDQMTKSYTNVPADDVSGNK
Sbjct: 601 MEVIAEDNRFIYDGIDSNFEPELVFLEFFEALLSFAFICVTDQMTKSYTNVPADDVSGNK 660
Query: 661 HETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSV 720
HETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSV
Sbjct: 661 HETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSV 720
Query: 721 SHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNNTYVFFVNTLFHAYKRE 780
SHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNN YVFFVNTLFHAYKRE
Sbjct: 721 SHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNNMYVFFVNTLFHAYKRE 780
Query: 781 EAIKEKIRADRLRSTAQAQQRKMEDDELEARLNIFILREEEAKRHDYEVDITVLKEPADV 840
EAIKEKIRADRLRSTAQAQQRKMEDDELEARLNIFILREEEAKRHDYEVDITVLKEPADV
Sbjct: 781 EAIKEKIRADRLRSTAQAQQRKMEDDELEARLNIFILREEEAKRHDYEVDITVLKEPADV 840
Query: 841 SSSHLILDPPKEDVTVSPSSKTITSKKKKK 870
SSSHLILDPPKEDVTVSPSSKTITSKKKKK
Sbjct: 841 SSSHLILDPPKEDVTVSPSSKTITSKKKKK 870
>gi|13376267 MORN repeat containing 1 [Homo sapiens]
Length = 497
Score = 103 bits (258), Expect = 5e-22
Identities = 64/174 (36%), Positives = 87/174 (50%), Gaps = 5/174 (2%)
Query: 86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWA-DGLKYEGDFVKNVPMNH 144
YEGE G G G F+ G Y G F +G + G+G WA G + G FV P +
Sbjct: 39 YEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDTFSGQFVLGEPQGY 98
Query: 145 GVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWY 204
GV + G YEGEV +GMR G G F Y G + + KRHG G + + Q G Y
Sbjct: 99 GVMEYKAGGCYEGEVSHGMREGHG-FLVDRDGQVYQGSFHDNKRHGPGQMLF-QNGD-KY 155
Query: 205 EGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERG 258
+GDWV++ ++G G+ G+ Y+GQW ++ G G M + Y G W G
Sbjct: 156 DGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAH-CSGVTYYGLWING 208
Score = 92.8 bits (229), Expect = 1e-18
Identities = 62/223 (27%), Positives = 98/223 (43%), Gaps = 37/223 (16%)
Query: 119 HGQGTYIWADGL-KYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPV 177
+G G Y++ + +YEG++ HG + DGS YEG V+G G G +
Sbjct: 25 NGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWSGD 84
Query: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRH 237
++ G + G+ G G + Y G YEG+ +++G G + G +Y+G + DN RH
Sbjct: 85 TFSGQFVLGEPQGYGVMEYKAGGC--YEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRH 142
Query: 238 GEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRG 297
G G+M + QNG ++Y G++V R G G
Sbjct: 143 GPGQMLF---------------QNG-------------------DKYDGDWVRDRRQGHG 168
Query: 298 KFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIA 340
A G+ Y G+W S+ G+G + +G Y G + N H A
Sbjct: 169 VLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHPA 211
Score = 86.3 bits (212), Expect = 1e-16
Identities = 49/154 (31%), Positives = 72/154 (46%), Gaps = 11/154 (7%)
Query: 188 RHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTT 247
R+G G +Y YEG+W K G G +K G+ YEG + D GEGR W +
Sbjct: 24 RNGYG-VYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAFVDGEITGEGRRHWAWS 82
Query: 248 NEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMY 307
+ ++G++ G G+G +Y Y GE +G R G G G +Y
Sbjct: 83 GDTFSGQFVLGEPQGYGV----------MEYKAGGCYEGEVSHGMREGHGFLVDRDGQVY 132
Query: 308 DGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
G + NK+HG G++ F+NG Y+G + D G
Sbjct: 133 QGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQG 166
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 3/126 (2%)
Query: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
+++ G+ V G +G G ++ G Y G S G+ G G + DG Y+G F N
Sbjct: 84 DTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHG 143
Query: 144 HGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCW 203
G + +G Y+G+ V R G G+ +C+ +Y G W + G GS+ + T
Sbjct: 144 PGQMLFQNGDKYDGDWVRDRRQGHGVLRCA-DGSTYKGQWHSDVFSGLGSMAHCSGVT-- 200
Query: 204 YEGDWV 209
Y G W+
Sbjct: 201 YYGLWI 206
Score = 35.0 bits (79), Expect = 0.30
Identities = 16/58 (27%), Positives = 27/58 (46%)
Query: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVP 141
+ Y+G+ VR +G G G TY+G + + G G+ G+ Y G ++ P
Sbjct: 153 DKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWINGHP 210
>gi|50355990 MORN repeat containing 3 [Homo sapiens]
Length = 240
Score = 100 bits (248), Expect = 8e-21
Identities = 56/163 (34%), Positives = 86/163 (52%), Gaps = 10/163 (6%)
Query: 109 YRGMFSEGLMHGQGTYIWA-DGLKYEGDFVKNVPMNHGVYTWPD-GSMYEGEVVNGMRNG 166
++G + +G + ++A +G Y G++ NV G W G++YEG+ G R+G
Sbjct: 14 WKGWDRKAQRNGLRSQVYAVNGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDG 73
Query: 167 FGMFKCSTQPVS-----YIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCY 221
+G Q Y G W K+ G G ++ + +YEGDW + + GWG Y
Sbjct: 74 YGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKE--YYEGDWCGSQRSGWGRMYY 131
Query: 222 KSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFG 264
+G+IYEGQWE++ +GEG +R L Y G WERG++NG G
Sbjct: 132 SNGDIYEGQWENDKPNGEGMLR-LKNGNRYEGCWERGMKNGAG 173
Score = 86.3 bits (212), Expect = 1e-16
Identities = 45/154 (29%), Positives = 78/154 (50%), Gaps = 29/154 (18%)
Query: 210 QNIKKGWGIRCYKSG----------NIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGI 259
+++ KGW + ++G + Y G+WEDN++HG+G W Y G W+ G
Sbjct: 11 ESLWKGWDRKAQRNGLRSQVYAVNGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGK 70
Query: 260 QNGFGT--------------HTWFLKRIRSSQYPL-----RNEYIGEFVNGYRHGRGKFY 300
++G+GT ++ + K + S Y + + Y G++ R G G+ Y
Sbjct: 71 RDGYGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMY 130
Query: 301 YASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAF 334
Y++G +Y+G+W ++K +G G L KNG YEG +
Sbjct: 131 YSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCW 164
Score = 82.0 bits (201), Expect = 2e-15
Identities = 50/157 (31%), Positives = 74/157 (47%), Gaps = 10/157 (6%)
Query: 106 GCTYRGMFSEGLMHGQGTYIWAD-GLKYEGDFVKNVPMNHGVYTWPDGS------MYEGE 158
G Y G + + + HG+GT +W G YEGD+ +G + PD +Y G
Sbjct: 35 GDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSGW 94
Query: 159 VVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGI 218
++G+G+ + Y G WC +R G G +YY+ YEG W + G G+
Sbjct: 95 WKGDKKSGYGIQFFGPKEY-YEGDWCGSQRSGWGRMYYSNGDI--YEGQWENDKPNGEGM 151
Query: 219 RCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRW 255
K+GN YEG WE M++G GR L + + G W
Sbjct: 152 LRLKNGNRYEGCWERGMKNGAGRFFHLDHGQLFEGFW 188
Score = 38.9 bits (89), Expect = 0.021
Identities = 25/87 (28%), Positives = 36/87 (41%)
Query: 97 GEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYE 156
G G F Y G + G G +++G YEG + + P G+ +G+ YE
Sbjct: 102 GYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYE 161
Query: 157 GEVVNGMRNGFGMFKCSTQPVSYIGHW 183
G GM+NG G F + G W
Sbjct: 162 GCWERGMKNGAGRFFHLDHGQLFEGFW 188
Score = 33.9 bits (76), Expect = 0.67
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 1/56 (1%)
Query: 86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWAD-GLKYEGDFVKNV 140
YEG+ GEG + G Y G + G+ +G G + D G +EG +V N+
Sbjct: 137 YEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNGAGRFFHLDHGQLFEGFWVDNM 192
Score = 33.5 bits (75), Expect = 0.88
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
Query: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
E YEG+ G G + G Y G + +G+G +G +YEG + + +
Sbjct: 112 EYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNG 171
Query: 144 HGVYTWPD-GSMYEGEVVNGMRNGFGMFKCST 174
G + D G ++EG V+ M KC T
Sbjct: 172 AGRFFHLDHGQLFEGFWVDNMA------KCGT 197
>gi|40316935 alsin isoform 1 [Homo sapiens]
Length = 1657
Score = 97.8 bits (242), Expect = 4e-20
Identities = 61/214 (28%), Positives = 96/214 (44%), Gaps = 42/214 (19%)
Query: 132 YEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVS----YIGHWCNGK 187
Y+G ++ P GV WPDG MY G NG+ +G+G ++ + ++ Y+GHW GK
Sbjct: 1049 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGK 1108
Query: 188 RHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMR--WL 245
G+ G+ Y SG ++EG ++DNMRHG G +R L
Sbjct: 1109 MCGQ-------------------------GVYSYASGEVFEGCFQDNMRHGHGLLRSGKL 1143
Query: 246 TTNEE--YTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYAS 303
T++ + G+W + G+G +Y+G + + G G
Sbjct: 1144 TSSSPSMFIGQWVMDKKAGYGVF---------DDITRGEKYMGMWQDDVCQGNGVVVTQF 1194
Query: 304 GAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSND 337
G Y+G + NK G G L ++ +YEG FS+D
Sbjct: 1195 GLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDD 1228
Score = 70.1 bits (170), Expect = 8e-12
Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 14/202 (6%)
Query: 52 LNEVKPKKDRQNVQQNED----ASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGC 107
++++ P +VQ+ E +++Y +L +Y+G + G G G + G
Sbjct: 1011 MSDLPPYGSGSSVQRQEPPISRSAKYTFYKDPRLKDATYDGRWLSGKPHGRGVLKWPDGK 1070
Query: 108 TYRGMFSEGLMHGQGTYIWADGL-----KYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNG 162
Y GMF GL G G Y + Y G + + GVY++ G ++EG +
Sbjct: 1071 MYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDN 1130
Query: 163 MRNGFGMFK----CSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGI 218
MR+G G+ + S+ P +IG W K+ G G G Y G W ++ +G G+
Sbjct: 1131 MRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGE-KYMGMWQDDVCQGNGV 1189
Query: 219 RCYKSGNIYEGQWEDNMRHGEG 240
+ G YEG + N G G
Sbjct: 1190 VVTQFGLYYEGNFHLNKMMGNG 1211
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 78 LTKLIVESYEGEKVRGLYEGEG-FAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDF 136
LT + G+ V G G F G Y GM+ + + G G + GL YEG+F
Sbjct: 1143 LTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNF 1202
Query: 137 VKNVPMNHGVYTWPDGSMYEGE 158
N M +GV D ++YEGE
Sbjct: 1203 HLNKMMGNGVLLSEDDTIYEGE 1224
Score = 41.6 bits (96), Expect = 0.003
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 305 AMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEV 347
A YDG W+S K HG G L + +G++Y G F N G+ + +
Sbjct: 1047 ATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRI 1089
Score = 39.3 bits (90), Expect = 0.016
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 6/76 (7%)
Query: 88 GEKVRGLYE-----GEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPM 142
GEK G+++ G G Q G Y G F M G G + D YEG+F + +
Sbjct: 1172 GEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDDWTL 1231
Query: 143 N-HGVYTWPDGSMYEG 157
+ G T P+G EG
Sbjct: 1232 SGKGTLTMPNGDYIEG 1247
>gi|18254456 testis-specific gene A2 [Homo sapiens]
Length = 309
Score = 93.2 bits (230), Expect = 9e-19
Identities = 49/134 (36%), Positives = 72/134 (53%), Gaps = 3/134 (2%)
Query: 83 VESYEGEKVR-GLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVP 141
+ YEG + G G G A G TY G + G HGQG Y + +G +Y G++V+N
Sbjct: 17 IGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKK 76
Query: 142 MNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGT 201
G + +PDGS YEGE N +R+G G++ +Y G W +RHG+G+ Y + G+
Sbjct: 77 HGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINND-TYTGEWFAHQRHGQGTYLYAETGS 135
Query: 202 CWYEGDWVQNIKKG 215
Y G WV ++G
Sbjct: 136 -KYVGTWVNGQQEG 148
Score = 93.2 bits (230), Expect = 9e-19
Identities = 50/162 (30%), Positives = 77/162 (47%), Gaps = 14/162 (8%)
Query: 150 PDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWV 209
P+G YEG G R+G G++K YIG + K+HG+G+ Y YEG+W
Sbjct: 39 PNGDTYEGSYEFGKRHGQGIYKFKNG-ARYIGEYVRNKKHGQGTFIYPDGSR--YEGEWA 95
Query: 210 QNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWF 269
+++ G G+ Y + + Y G+W + RHG+G + T +Y G W G Q G
Sbjct: 96 NDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG------- 148
Query: 270 LKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEW 311
+ L + Y G+F+N G GK+ + G GE+
Sbjct: 149 ----TAELIHLNHRYQGKFLNKNPVGPGKYVFDVGCEQHGEY 186
Score = 83.6 bits (205), Expect = 7e-16
Identities = 48/158 (30%), Positives = 76/158 (48%), Gaps = 6/158 (3%)
Query: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
++YEG G G+G F+ G Y G + HGQGT+I+ DG +YEG++ ++
Sbjct: 42 DTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHG 101
Query: 144 HGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGS-IYYNQEGTC 202
HGVY + + Y GE R+G G + + Y+G W NG++ G I+ N
Sbjct: 102 HGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEGTAELIHLNHR--- 158
Query: 203 WYEGDWVQNIKKGWGIRCYKSGNIYEGQWE-DNMRHGE 239
Y+G ++ G G + G G++ +M GE
Sbjct: 159 -YQGKFLNKNPVGPGKYVFDVGCEQHGEYRLTDMERGE 195
Score = 73.2 bits (178), Expect = 1e-12
Identities = 42/134 (31%), Positives = 64/134 (47%), Gaps = 12/134 (8%)
Query: 213 KKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKR 272
+ G G +G+ YEG +E RHG+G ++ Y G + R ++G GT
Sbjct: 30 RHGRGRARLPNGDTYEGSYEFGKRHGQGIYKF-KNGARYIGEYVRNKKHGQGTFI----- 83
Query: 273 IRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTF-KNGRVYE 331
YP + Y GE+ N RHG G +YY + Y GEW ++++HG G + + G Y
Sbjct: 84 -----YPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYV 138
Query: 332 GAFSNDHIAGFPDL 345
G + N G +L
Sbjct: 139 GTWVNGQQEGTAEL 152
Score = 67.8 bits (164), Expect = 4e-11
Identities = 39/111 (35%), Positives = 54/111 (48%), Gaps = 15/111 (13%)
Query: 224 GNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRN- 282
G G+ E RHG GR R L + Y G +E G ++G G Y +N
Sbjct: 18 GEYEGGRNEAGERHGRGRAR-LPNGDTYEGSYEFGKRHGQGI------------YKFKNG 64
Query: 283 -EYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEG 332
YIGE+V +HG+G F Y G+ Y+GEW ++ +HG G + N Y G
Sbjct: 65 ARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTG 115
Score = 60.1 bits (144), Expect = 9e-09
Identities = 32/85 (37%), Positives = 47/85 (55%), Gaps = 10/85 (11%)
Query: 253 GRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWV 312
GR E G ++G G ++ P + Y G + G RHG+G + + +GA Y GE+V
Sbjct: 23 GRNEAGERHGRGR----------ARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYV 72
Query: 313 SNKKHGMGRLTFKNGRVYEGAFSND 337
NKKHG G + +G YEG ++ND
Sbjct: 73 RNKKHGQGTFIYPDGSRYEGEWAND 97
>gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
Length = 953
Score = 85.9 bits (211), Expect = 1e-16
Identities = 55/209 (26%), Positives = 88/209 (42%), Gaps = 33/209 (15%)
Query: 132 YEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGK 191
YEG++ + P G WPDG + G G+ +GFG+
Sbjct: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQA---------------- 401
Query: 192 GSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMR---WLTTN 248
+++ Y+ W + G+GI Y + +Y+G +++ +RHG G +
Sbjct: 402 -----SEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQP 456
Query: 249 EEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYD 308
YTG WERG ++G+G YIG + G RHG G +G Y
Sbjct: 457 FRYTGHWERGQRSGYGI---------EEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQ 507
Query: 309 GEWVSNKKHGMGRLTFKNGRVYEGAFSND 337
G + ++K G G L ++ +YEG F+ D
Sbjct: 508 GTFQADKTVGPGILLSEDDSLYEGTFTRD 536
Score = 74.3 bits (181), Expect = 4e-13
Identities = 49/170 (28%), Positives = 80/170 (47%), Gaps = 15/170 (8%)
Query: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGN-----IYEGQWE 232
+Y G WC G+ HGKG++ + + G++ Q ++ G+GIR + Y+ W
Sbjct: 357 TYEGEWCRGRPHGKGTLKWPDGRN--HVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414
Query: 233 DNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGY 292
+ G G + +T+E Y G ++ G+++GFG L+ + P R Y G + G
Sbjct: 415 EGSMCGYGICEY-STDEVYKGYFQEGLRHGFGV----LESGPQAPQPFR--YTGHWERGQ 467
Query: 293 RHGRGKFYYAS-GAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
R G G G Y G W + ++HG G + + G Y+G F D G
Sbjct: 468 RSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVG 517
Score = 72.4 bits (176), Expect = 2e-12
Identities = 54/203 (26%), Positives = 88/203 (43%), Gaps = 17/203 (8%)
Query: 46 PLLGMQLNEVKPKKDRQNVQQNEDASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQG 105
P+LG L +P R ++Y +L +YEGE RG G+G +
Sbjct: 326 PVLGAGLEPSQPPDCR--------CAEYTFQAEGRLCQATYEGEWCRGRPHGKGTLKWPD 377
Query: 106 GCTYRGMFSEGLMHGQGTYIWADGLK-----YEGDFVKNVPMNHGVYTWPDGSMYEGEVV 160
G + G F +GL HG G + + Y+ + + +G+ + +Y+G
Sbjct: 378 GRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQ 437
Query: 161 NGMRNGFGMFKC---STQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWG 217
G+R+GFG+ + + QP Y GHW G+R G G G Y G W + G G
Sbjct: 438 EGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGE-RYIGMWQAGQRHGPG 496
Query: 218 IRCYKSGNIYEGQWEDNMRHGEG 240
+ ++G Y+G ++ + G G
Sbjct: 497 VMVTQAGVCYQGTFQADKTVGPG 519
Score = 42.0 bits (97), Expect = 0.002
Identities = 27/84 (32%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
Query: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVP-M 142
E Y G G G G Q G Y+G F G G + D YEG F +++ M
Sbjct: 481 ERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTRDLTLM 540
Query: 143 NHGVYTWPDGSMYEGEVVNGMRNG 166
G T+P+G EG +G G
Sbjct: 541 GKGKVTFPNGFTLEGSFGSGAGRG 564
Score = 39.3 bits (90), Expect = 0.016
Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 86 YEGEKVRGLYEGEGFAAF-QGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144
Y G RG G G G Y GM+ G HG G + G+ Y+G F + +
Sbjct: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGP 518
Query: 145 GVYTWPDGSMYEG 157
G+ D S+YEG
Sbjct: 519 GILLSEDDSLYEG 531
Score = 38.1 bits (87), Expect = 0.036
Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 19/113 (16%)
Query: 239 EGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGK 298
EGR+ T Y G W RG +G GT W P ++G F G HG G
Sbjct: 350 EGRLCQAT----YEGEWCRGRPHGKGTLKW----------PDGRNHVGNFCQGLEHGFGI 395
Query: 299 FYYASGA-----MYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLE 346
+ Y W G G + VY+G F GF LE
Sbjct: 396 RLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLE 448
>gi|21735575 junctophilin 1 [Homo sapiens]
Length = 661
Score = 81.3 bits (199), Expect = 4e-15
Identities = 47/139 (33%), Positives = 66/139 (47%), Gaps = 5/139 (3%)
Query: 103 FQGGCTYRGMFSEGLMHGQGTYIWADGL-KYEGDFVKNVPMNHGVYTWPDGSMYEGEVVN 161
F G TY G + EG HG G G +Y G + + G YTWP G+ Y+G
Sbjct: 8 FDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGG-YTWPSGNTYQGYWAQ 66
Query: 162 GMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCY 221
G R+G G+ + Y G W +G + G+ + + YEG W ++ G+G+ Y
Sbjct: 67 GKRHGLGVE--TKGKWMYRGEWSHGFK-GRYGVRQSLCTPARYEGTWSNGLQDGYGVETY 123
Query: 222 KSGNIYEGQWEDNMRHGEG 240
G Y+GQW MRHG G
Sbjct: 124 GDGGTYQGQWAGGMRHGYG 142
Score = 74.7 bits (182), Expect = 3e-13
Identities = 47/146 (32%), Positives = 62/146 (42%), Gaps = 19/146 (13%)
Query: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRH 237
+Y G W GK HG G I +G Y G W + G + SGN Y+G W RH
Sbjct: 13 TYCGGWEEGKAHGHG-ICTGPKGQGEYSGSWSHGFEVVGGYT-WPSGNTYQGYWAQGKRH 70
Query: 238 GEG---RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRH 294
G G + +W+ Y G W G + +G +S P R Y G + NG +
Sbjct: 71 GLGVETKGKWM-----YRGEWSHGFKGRYGVR-------QSLCTPAR--YEGTWSNGLQD 116
Query: 295 GRGKFYYASGAMYDGEWVSNKKHGMG 320
G G Y G Y G+W +HG G
Sbjct: 117 GYGVETYGDGGTYQGQWAGGMRHGYG 142
Score = 72.4 bits (176), Expect = 2e-12
Identities = 74/307 (24%), Positives = 120/307 (39%), Gaps = 60/307 (19%)
Query: 88 GEKVRGLYEGE---GFAAFQG-----GCTYRGMFSEGLMHGQGTYI---------WADGL 130
G K +G Y G GF G G TY+G +++G HG G W+ G
Sbjct: 31 GPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGF 90
Query: 131 K--------------YEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKC---- 172
K YEG + + +GV T+ DG Y+G+ GMR+G+G+ +
Sbjct: 91 KGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYG 150
Query: 173 ---------STQPVSYIGHWCNGK-RHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYK 222
T S NG H + + GT G +V N + K
Sbjct: 151 MATVIRSPLRTSLASLRSEQSNGSVLHDAAAAADSPAGT---RGGFVLNFHADAELAGKK 207
Query: 223 SGNIYE-GQWEDNMRHGEGRMRWLTTNEEYTGRWERG---IQNGFGTHTWFLKRIRSSQY 278
G ++ G +M+ + + +++ + R + I + T +
Sbjct: 208 KGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFC 267
Query: 279 PLRNE--------YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVY 330
P+ + Y+GE+ N R+G G ++G Y+GEW +NK+HG G F +G
Sbjct: 268 PVEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKE 327
Query: 331 EGAFSND 337
EG + N+
Sbjct: 328 EGKYKNN 334
Score = 65.9 bits (159), Expect = 2e-10
Identities = 49/178 (27%), Positives = 69/178 (38%), Gaps = 41/178 (23%)
Query: 122 GTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPV--SY 179
G + + DG Y G + + HG+ T P G +GE +GF + T P +Y
Sbjct: 4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKG---QGEYSGSWSHGFEVVGGYTWPSGNTY 60
Query: 180 IGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGE 239
G+W GKRHG G +G W+ Y G+W +
Sbjct: 61 QGYWAQGKRHGLG---------VETKGKWM-----------------YRGEWSHGFKGRY 94
Query: 240 GRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRG 297
G + L T Y G W G+Q+G+G T Y Y G++ G RHG G
Sbjct: 95 GVRQSLCTPARYEGTWSNGLQDGYGVET----------YGDGGTYQGQWAGGMRHGYG 142
Score = 43.9 bits (102), Expect = 7e-04
Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
Query: 173 STQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWE 232
+T +Y+G W N KR+G G + YEG+W N + G+G + G+ EG+++
Sbjct: 275 ATTTETYMGEWKNDKRNGFG--VSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYK 332
Query: 233 DNM 235
+N+
Sbjct: 333 NNI 335
Score = 40.0 bits (92), Expect = 0.009
Identities = 19/56 (33%), Positives = 30/56 (53%)
Query: 108 TYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGM 163
TY G + +G G ++G+KYEG++ N +G +PDGS EG+ N +
Sbjct: 280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
Score = 36.6 bits (83), Expect = 0.10
Identities = 18/57 (31%), Positives = 26/57 (45%)
Query: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNV 140
E+Y GE G G + G Y G ++ HG G ++ DG K EG + N+
Sbjct: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
Score = 35.0 bits (79), Expect = 0.30
Identities = 15/37 (40%), Positives = 21/37 (56%)
Query: 86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQG 122
YEG GL +G G + G TY+G ++ G+ HG G
Sbjct: 106 YEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYG 142
Score = 30.0 bits (66), Expect = 9.7
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 297 GKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR-VYEGAFSN 336
G+F + G Y G W K HG G T G+ Y G++S+
Sbjct: 4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSH 44
>gi|21704283 junctophilin 3 [Homo sapiens]
Length = 748
Score = 78.2 bits (191), Expect = 3e-14
Identities = 46/141 (32%), Positives = 65/141 (46%), Gaps = 9/141 (6%)
Query: 103 FQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH---GVYTWPDGSMYEGEV 159
F G +Y G + +G HG G G K +G++ + GVYTWP G+ Y+G
Sbjct: 9 FDDGGSYCGGWEDGKAHGHGV---CTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTW 65
Query: 160 VNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIR 219
G R+G G+ S Y G W +G + G+ + YEG W ++ G+G
Sbjct: 66 AQGKRHGIGLE--SKGKWVYKGEWTHGFK-GRYGVRECAGNGAKYEGTWSNGLQDGYGTE 122
Query: 220 CYKSGNIYEGQWEDNMRHGEG 240
Y G Y+GQW MR G G
Sbjct: 123 TYSDGGTYQGQWVGGMRQGYG 143
Score = 77.4 bits (189), Expect = 5e-14
Identities = 48/150 (32%), Positives = 70/150 (46%), Gaps = 10/150 (6%)
Query: 118 MHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPV 177
M G + + DG Y G + HGV T P G +GE +GF + T P
Sbjct: 1 MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKG---QGEYTGSWSHGFEVLGVYTWPS 57
Query: 178 --SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIR-CYKSGNIYEGQWEDN 234
+Y G W GKRHG G +G Y+G+W K +G+R C +G YEG W +
Sbjct: 58 GNTYQGTWAQGKRHGIG---LESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNG 114
Query: 235 MRHGEGRMRWLTTNEEYTGRWERGIQNGFG 264
++ G G + + Y G+W G++ G+G
Sbjct: 115 LQDGYGTETY-SDGGTYQGQWVGGMRQGYG 143
Score = 73.6 bits (179), Expect = 8e-13
Identities = 44/146 (30%), Positives = 62/146 (42%), Gaps = 19/146 (13%)
Query: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRH 237
SY G W +GK HG G + +G Y G W + G+ + SGN Y+G W RH
Sbjct: 14 SYCGGWEDGKAHGHG-VCTGPKGQGEYTGSWSHGFEV-LGVYTWPSGNTYQGTWAQGKRH 71
Query: 238 G---EGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRH 294
G E + +W+ Y G W G + +G + Y G + NG +
Sbjct: 72 GIGLESKGKWV-----YKGEWTHGFKGRYGVRECAGNGAK---------YEGTWSNGLQD 117
Query: 295 GRGKFYYASGAMYDGEWVSNKKHGMG 320
G G Y+ G Y G+WV + G G
Sbjct: 118 GYGTETYSDGGTYQGQWVGGMRQGYG 143
Score = 62.4 bits (150), Expect = 2e-09
Identities = 40/135 (29%), Positives = 53/135 (39%), Gaps = 34/135 (25%)
Query: 221 YKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPL 280
+ G Y G WED HG G EYTG W G + G +TW P
Sbjct: 9 FDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFE-VLGVYTW----------PS 57
Query: 281 RNEYIGEFVNGYRHG-----RGKFYY------------------ASGAMYDGEWVSNKKH 317
N Y G + G RHG +GK+ Y +GA Y+G W + +
Sbjct: 58 GNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQD 117
Query: 318 GMGRLTFKNGRVYEG 332
G G T+ +G Y+G
Sbjct: 118 GYGTETYSDGGTYQG 132
Score = 53.9 bits (128), Expect = 6e-07
Identities = 23/58 (39%), Positives = 34/58 (58%)
Query: 284 YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
Y+GE+ N R G G + G Y+GEW SN++HG G +TF +G EG + + + G
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVG 345
Score = 50.1 bits (118), Expect = 9e-06
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 85 SYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWA-DGLKYEGDFVKNVPMN 143
+Y+G +G G G + +G Y+G ++ G G A +G KYEG + +
Sbjct: 60 TYQGTWAQGKRHGIGLES-KGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDG 118
Query: 144 HGVYTWPDGSMYEGEVVNGMRNGFGM 169
+G T+ DG Y+G+ V GMR G+G+
Sbjct: 119 YGTETYSDGGTYQGQWVGGMRQGYGV 144
Score = 44.3 bits (103), Expect = 5e-04
Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 173 STQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWE 232
+T +Y+G W N KR G G + +G YEG+W N + G+G + G EG+++
Sbjct: 282 ATTTETYVGEWKNDKRSGFG-VSQRSDGLK-YEGEWASNRRHGYGCMTFPDGTKEEGKYK 339
Query: 233 DNMRHGEGR 241
N+ G R
Sbjct: 340 QNILVGGKR 348
Score = 41.6 bits (96), Expect = 0.003
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 204 YEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNG 262
Y G+W + + G+G+ G YEG+W N RHG G M + +E G++++ I G
Sbjct: 288 YVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKE-EGKYKQNILVG 345
Score = 40.4 bits (93), Expect = 0.007
Identities = 20/51 (39%), Positives = 28/51 (54%)
Query: 108 TYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGE 158
TY G + G G +DGLKYEG++ N +G T+PDG+ EG+
Sbjct: 287 TYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGK 337
Score = 35.8 bits (81), Expect = 0.18
Identities = 18/57 (31%), Positives = 26/57 (45%)
Query: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNV 140
E+Y GE G G + G Y G ++ HG G + DG K EG + +N+
Sbjct: 286 ETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNI 342
Score = 30.0 bits (66), Expect = 9.7
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 297 GKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR-VYEGAFSN 336
G+F + G Y G W K HG G T G+ Y G++S+
Sbjct: 5 GRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSH 45
>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
Length = 696
Score = 75.1 bits (183), Expect = 3e-13
Identities = 46/141 (32%), Positives = 65/141 (46%), Gaps = 9/141 (6%)
Query: 103 FQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH---GVYTWPDGSMYEGEV 159
F G Y G + G HG G G K +G++ + GVYTWP G+ +EG
Sbjct: 8 FDDGGAYCGGWEGGKAHGHGL---CTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYW 64
Query: 160 VNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIR 219
G R+G G+ Y G W +G + G+ I + YEG W ++ G+G
Sbjct: 65 SQGKRHGLGIETKGRW--LYKGEWTHGFK-GRYGIRQSSSSGAKYEGTWNNGLQDGYGTE 121
Query: 220 CYKSGNIYEGQWEDNMRHGEG 240
Y G Y+GQ+ + MRHG G
Sbjct: 122 TYADGGTYQGQFTNGMRHGYG 142
Score = 73.9 bits (180), Expect = 6e-13
Identities = 48/146 (32%), Positives = 65/146 (44%), Gaps = 19/146 (13%)
Query: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRH 237
+Y G W GK HG G + +G Y G W + G+ + SGN +EG W RH
Sbjct: 13 AYCGGWEGGKAHGHG-LCTGPKGQGEYSGSWNFGFEVA-GVYTWPSGNTFEGYWSQGKRH 70
Query: 238 GEG---RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRH 294
G G + RWL Y G W G + +G IR S +Y G + NG +
Sbjct: 71 GLGIETKGRWL-----YKGEWTHGFKGRYG--------IRQSSSS-GAKYEGTWNNGLQD 116
Query: 295 GRGKFYYASGAMYDGEWVSNKKHGMG 320
G G YA G Y G++ + +HG G
Sbjct: 117 GYGTETYADGGTYQGQFTNGMRHGYG 142
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 31/113 (27%)
Query: 88 GEKVRGLYEGE--------GFAAFQGGCTYRGMFSEGLMHG-----QGTYIW-------- 126
G K +G Y G G + G T+ G +S+G HG +G +++
Sbjct: 31 GPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGF 90
Query: 127 ----------ADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGM 169
+ G KYEG + + +G T+ DG Y+G+ NGMR+G+G+
Sbjct: 91 KGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGV 143
Score = 46.2 bits (108), Expect = 1e-04
Identities = 21/54 (38%), Positives = 31/54 (57%)
Query: 284 YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSND 337
Y+GE+ N R G G +SG Y+GEW+ N +HG G T +G EG + ++
Sbjct: 291 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHN 344
Score = 43.5 bits (101), Expect = 8e-04
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 173 STQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWE 232
+T +Y+G W N KR G G + YEG+W+ N++ G+G G+ EG++
Sbjct: 285 ATTTETYMGEWKNDKRSGFG--VSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYR 342
Query: 233 DNMRHGEGRMRWL 245
N+ + + R L
Sbjct: 343 HNVLVKDTKRRML 355
Score = 38.1 bits (87), Expect = 0.036
Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
Query: 55 VKPKKDRQNVQQNEDASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFS 114
V ++ R + +++ +S ++ T + E+ EG +E + A TY G +
Sbjct: 239 VGSQRSRVSFLKSDLSSGASDAASTASLGEAAEGADEAAPFEADIDATTTE--TYMGEWK 296
Query: 115 EGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGE 158
G G + GL+YEG+++ N+ +G T PDG EG+
Sbjct: 297 NDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGK 340
Score = 37.4 bits (85), Expect = 0.061
Identities = 16/37 (43%), Positives = 21/37 (56%)
Query: 86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQG 122
YEG GL +G G + G TY+G F+ G+ HG G
Sbjct: 106 YEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYG 142
Score = 35.0 bits (79), Expect = 0.30
Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 1/73 (1%)
Query: 68 EDASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWA 127
++A+ +E I E+Y GE G G + G Y G + + L HG G
Sbjct: 274 DEAAPFEADI-DATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLP 332
Query: 128 DGLKYEGDFVKNV 140
DG + EG + NV
Sbjct: 333 DGHREEGKYRHNV 345
Score = 30.0 bits (66), Expect = 9.7
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 7/59 (11%)
Query: 132 YEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGK-RH 189
Y G++ + GV G YEGE ++ +R+G+G C+T P GH GK RH
Sbjct: 291 YMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYG---CTTLP---DGHREEGKYRH 343
>gi|225690502 junctophilin 4 [Homo sapiens]
Length = 628
Score = 69.3 bits (168), Expect = 1e-11
Identities = 49/146 (33%), Positives = 67/146 (45%), Gaps = 9/146 (6%)
Query: 97 GEGFAAFQGGCTYRGMFSEGLMHGQG--TYIWADGLKYEGDFVKNVPMNHGVYTWPDGSM 154
G F GGC Y G + G HG G T A G +Y G + + GV+T P G
Sbjct: 4 GGKFDFDDGGC-YVGGWEAGRAHGYGVCTGPGAQG-EYSGCWAHGFE-SLGVFTGPGGHS 60
Query: 155 YEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKK 214
Y+G G R G G+ + S +Y G W G + G+ ++ + G Y G W +
Sbjct: 61 YQGHWQQGKREGLGVERKSRW--TYRGEWLGGLK-GRSGVWESVSGLR-YAGLWKDGFQD 116
Query: 215 GWGIRCYKSGNIYEGQWEDNMRHGEG 240
G+G Y G Y+GQW+ RHG G
Sbjct: 117 GYGTETYSDGGTYQGQWQAGKRHGYG 142
Score = 63.2 bits (152), Expect = 1e-09
Identities = 43/145 (29%), Positives = 62/145 (42%), Gaps = 20/145 (13%)
Query: 179 YIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHG 238
Y+G W G+ HG G + Y G W + G+ G+ Y+G W+ R G
Sbjct: 15 YVGGWEAGRAHGYG-VCTGPGAQGEYSGCWAHGFES-LGVFTGPGGHSYQGHWQQGKREG 72
Query: 239 EG---RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHG 295
G + RW Y G W G++ G W S LR Y G + +G++ G
Sbjct: 73 LGVERKSRWT-----YRGEWLGGLKGRSGV--W------ESVSGLR--YAGLWKDGFQDG 117
Query: 296 RGKFYYASGAMYDGEWVSNKKHGMG 320
G Y+ G Y G+W + K+HG G
Sbjct: 118 YGTETYSDGGTYQGQWQAGKRHGYG 142
Score = 49.3 bits (116), Expect = 2e-05
Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 11/123 (8%)
Query: 221 YKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQN-----GFGTHTWFLKRIRS 275
+ G Y G WE HG G EY+G W G ++ G G H++ +
Sbjct: 9 FDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGHWQQG 68
Query: 276 SQYPLRNE------YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRV 329
+ L E Y GE++ G + G + SG Y G W + G G T+ +G
Sbjct: 69 KREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGT 128
Query: 330 YEG 332
Y+G
Sbjct: 129 YQG 131
Score = 47.4 bits (111), Expect = 6e-05
Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 85 SYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144
SY+G +G EG G + TYRG + GL G + GL+Y G + +
Sbjct: 60 SYQGHWQQGKREGLGVER-KSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGY 118
Query: 145 GVYTWPDGSMYEGEVVNGMRNGFGM 169
G T+ DG Y+G+ G R+G+G+
Sbjct: 119 GTETYSDGGTYQGQWQAGKRHGYGV 143
Score = 45.1 bits (105), Expect = 3e-04
Identities = 20/56 (35%), Positives = 31/56 (55%)
Query: 284 YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHI 339
Y GE+ R G G ++G Y+GEW+ N++HG GR T +G EG + + +
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRL 337
Score = 43.9 bits (102), Expect = 7e-04
Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query: 95 YEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSM 154
+E G GG +Y+G + +G G G Y G+++ + GV+ G
Sbjct: 47 FESLGVFTGPGGHSYQGHWQQGKREGLGVE-RKSRWTYRGEWLGGLKGRSGVWESVSGLR 105
Query: 155 YEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKG---SIYYNQ 198
Y G +G ++G+G + + +Y G W GKRHG G S+ Y+Q
Sbjct: 106 YAGLWKDGFQDGYGT-ETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQ 151
Score = 40.0 bits (92), Expect = 0.009
Identities = 16/38 (42%), Positives = 23/38 (60%)
Query: 204 YEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGR 241
Y G+W + + G+G+ +G YEG+W N RHG GR
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGR 319
Score = 35.4 bits (80), Expect = 0.23
Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 179 YIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHG 238
Y G W +R G G + YEG+W+ N + G+G G+ EG+++ N
Sbjct: 282 YAGEWRADRRSGFG--VSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVH 339
Query: 239 EGRMRWL 245
GR+R L
Sbjct: 340 GGRVRSL 346
Score = 34.7 bits (78), Expect = 0.39
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 101 AAFQGGCT--YRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGE 158
A +G T Y G + G G ++GL+YEG+++ N +G T PDGS EG+
Sbjct: 272 ALIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGK 331
Score = 34.7 bits (78), Expect = 0.39
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 16/92 (17%)
Query: 246 TTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGA 305
+ E Y G W ++GFG SQ Y GE++ RHG G+ G+
Sbjct: 277 SATEVYAGEWRADRRSGFGV----------SQRSNGLRYEGEWLGNRRHGYGRTTRPDGS 326
Query: 306 MYDGEWVSNKKHGMGR------LTFKNGRVYE 331
+G++ N+ GR L + G+V E
Sbjct: 327 REEGKYKRNRLVHGGRVRSLLPLALRRGKVKE 358
Score = 30.4 bits (67), Expect = 7.4
Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 3/51 (5%)
Query: 297 GKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEV 347
GKF + G Y G W + + HG G T G +G +S GF L V
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCT---GPGAQGEYSGCWAHGFESLGV 52
>gi|225690500 junctophilin 4 [Homo sapiens]
Length = 628
Score = 69.3 bits (168), Expect = 1e-11
Identities = 49/146 (33%), Positives = 67/146 (45%), Gaps = 9/146 (6%)
Query: 97 GEGFAAFQGGCTYRGMFSEGLMHGQG--TYIWADGLKYEGDFVKNVPMNHGVYTWPDGSM 154
G F GGC Y G + G HG G T A G +Y G + + GV+T P G
Sbjct: 4 GGKFDFDDGGC-YVGGWEAGRAHGYGVCTGPGAQG-EYSGCWAHGFE-SLGVFTGPGGHS 60
Query: 155 YEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKK 214
Y+G G R G G+ + S +Y G W G + G+ ++ + G Y G W +
Sbjct: 61 YQGHWQQGKREGLGVERKSRW--TYRGEWLGGLK-GRSGVWESVSGLR-YAGLWKDGFQD 116
Query: 215 GWGIRCYKSGNIYEGQWEDNMRHGEG 240
G+G Y G Y+GQW+ RHG G
Sbjct: 117 GYGTETYSDGGTYQGQWQAGKRHGYG 142
Score = 63.2 bits (152), Expect = 1e-09
Identities = 43/145 (29%), Positives = 62/145 (42%), Gaps = 20/145 (13%)
Query: 179 YIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHG 238
Y+G W G+ HG G + Y G W + G+ G+ Y+G W+ R G
Sbjct: 15 YVGGWEAGRAHGYG-VCTGPGAQGEYSGCWAHGFES-LGVFTGPGGHSYQGHWQQGKREG 72
Query: 239 EG---RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHG 295
G + RW Y G W G++ G W S LR Y G + +G++ G
Sbjct: 73 LGVERKSRWT-----YRGEWLGGLKGRSGV--W------ESVSGLR--YAGLWKDGFQDG 117
Query: 296 RGKFYYASGAMYDGEWVSNKKHGMG 320
G Y+ G Y G+W + K+HG G
Sbjct: 118 YGTETYSDGGTYQGQWQAGKRHGYG 142
Score = 49.3 bits (116), Expect = 2e-05
Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 11/123 (8%)
Query: 221 YKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQN-----GFGTHTWFLKRIRS 275
+ G Y G WE HG G EY+G W G ++ G G H++ +
Sbjct: 9 FDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQGHWQQG 68
Query: 276 SQYPLRNE------YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRV 329
+ L E Y GE++ G + G + SG Y G W + G G T+ +G
Sbjct: 69 KREGLGVERKSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGYGTETYSDGGT 128
Query: 330 YEG 332
Y+G
Sbjct: 129 YQG 131
Score = 47.4 bits (111), Expect = 6e-05
Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 85 SYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144
SY+G +G EG G + TYRG + GL G + GL+Y G + +
Sbjct: 60 SYQGHWQQGKREGLGVER-KSRWTYRGEWLGGLKGRSGVWESVSGLRYAGLWKDGFQDGY 118
Query: 145 GVYTWPDGSMYEGEVVNGMRNGFGM 169
G T+ DG Y+G+ G R+G+G+
Sbjct: 119 GTETYSDGGTYQGQWQAGKRHGYGV 143
Score = 45.1 bits (105), Expect = 3e-04
Identities = 20/56 (35%), Positives = 31/56 (55%)
Query: 284 YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHI 339
Y GE+ R G G ++G Y+GEW+ N++HG GR T +G EG + + +
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRL 337
Score = 43.9 bits (102), Expect = 7e-04
Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query: 95 YEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSM 154
+E G GG +Y+G + +G G G Y G+++ + GV+ G
Sbjct: 47 FESLGVFTGPGGHSYQGHWQQGKREGLGVE-RKSRWTYRGEWLGGLKGRSGVWESVSGLR 105
Query: 155 YEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKG---SIYYNQ 198
Y G +G ++G+G + + +Y G W GKRHG G S+ Y+Q
Sbjct: 106 YAGLWKDGFQDGYGT-ETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQ 151
Score = 40.0 bits (92), Expect = 0.009
Identities = 16/38 (42%), Positives = 23/38 (60%)
Query: 204 YEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGR 241
Y G+W + + G+G+ +G YEG+W N RHG GR
Sbjct: 282 YAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGR 319
Score = 35.4 bits (80), Expect = 0.23
Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 179 YIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHG 238
Y G W +R G G + YEG+W+ N + G+G G+ EG+++ N
Sbjct: 282 YAGEWRADRRSGFG--VSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVH 339
Query: 239 EGRMRWL 245
GR+R L
Sbjct: 340 GGRVRSL 346
Score = 34.7 bits (78), Expect = 0.39
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 101 AAFQGGCT--YRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGE 158
A +G T Y G + G G ++GL+YEG+++ N +G T PDGS EG+
Sbjct: 272 ALIEGSATEVYAGEWRADRRSGFGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGK 331
Score = 34.7 bits (78), Expect = 0.39
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 16/92 (17%)
Query: 246 TTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGA 305
+ E Y G W ++GFG SQ Y GE++ RHG G+ G+
Sbjct: 277 SATEVYAGEWRADRRSGFGV----------SQRSNGLRYEGEWLGNRRHGYGRTTRPDGS 326
Query: 306 MYDGEWVSNKKHGMGR------LTFKNGRVYE 331
+G++ N+ GR L + G+V E
Sbjct: 327 REEGKYKRNRLVHGGRVRSLLPLALRRGKVKE 358
Score = 30.4 bits (67), Expect = 7.4
Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 3/51 (5%)
Query: 297 GKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEV 347
GKF + G Y G W + + HG G T G +G +S GF L V
Sbjct: 5 GKFDFDDGGCYVGGWEAGRAHGYGVCT---GPGAQGEYSGCWAHGFESLGV 52
>gi|149999376 MORN repeat containing 4 [Homo sapiens]
Length = 146
Score = 63.9 bits (154), Expect = 6e-10
Identities = 39/123 (31%), Positives = 58/123 (47%), Gaps = 15/123 (12%)
Query: 221 YKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPL 280
Y SG Y G+W++ RHG G++ + Y G +E G+ NGFG T +
Sbjct: 10 YSSGEEYRGEWKEGRRHGFGQLMF-ADGGTYLGHFENGLFNGFGVLT----------FSD 58
Query: 281 RNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR----VYEGAFSN 336
+ Y GEF G +G G F ++GE+ + + G G LTF +G EG F N
Sbjct: 59 GSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFEN 118
Query: 337 DHI 339
+ +
Sbjct: 119 NKL 121
Score = 63.9 bits (154), Expect = 6e-10
Identities = 34/86 (39%), Positives = 44/86 (51%)
Query: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
E Y GE G G G F G TY G F GL +G G ++DG +YEG+F +
Sbjct: 14 EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNG 73
Query: 144 HGVYTWPDGSMYEGEVVNGMRNGFGM 169
GV+ D +EGE NG +GFG+
Sbjct: 74 VGVFIRYDNMTFEGEFKNGRVDGFGL 99
Score = 63.2 bits (152), Expect = 1e-09
Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 98 EGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEG 157
+G + G YRG + EG HG G ++ADG Y G F + GV T+ DGS YEG
Sbjct: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEG 64
Query: 158 EVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYY 196
E G NG G+F +++ G + NG+ G G + +
Sbjct: 65 EFAQGKFNGVGVF-IRYDNMTFEGEFKNGRVDGFGLLTF 102
Score = 58.2 bits (139), Expect = 3e-08
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
Query: 246 TTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGA 305
++ EEY G W+ G ++GFG + Y+G F NG +G G ++ G+
Sbjct: 11 SSGEEYRGEWKEGRRHGFG----------QLMFADGGTYLGHFENGLFNGFGVLTFSDGS 60
Query: 306 MYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Y+GE+ K +G+G + +EG F N + GF
Sbjct: 61 RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97
Score = 52.8 bits (125), Expect = 1e-06
Identities = 25/69 (36%), Positives = 36/69 (52%)
Query: 85 SYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144
+Y G GL+ G G F G Y G F++G +G G +I D + +EG+F
Sbjct: 38 TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97
Query: 145 GVYTWPDGS 153
G+ T+PDGS
Sbjct: 98 GLLTFPDGS 106
Score = 50.1 bits (118), Expect = 9e-06
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 275 SSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAF 334
S Y EY GE+ G RHG G+ +A G Y G + + +G G LTF +G YEG F
Sbjct: 7 SFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEF 66
Query: 335 SNDHIAG 341
+ G
Sbjct: 67 AQGKFNG 73
Score = 49.3 bits (116), Expect = 2e-05
Identities = 21/47 (44%), Positives = 27/47 (57%)
Query: 296 RGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
+G F Y+SG Y GEW ++HG G+L F +G Y G F N GF
Sbjct: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGF 51
Score = 46.6 bits (109), Expect = 1e-04
Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Query: 142 MNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGT 201
+ G +T+ G Y GE G R+GFG + +Y+GH+ NG +G G + ++
Sbjct: 3 LTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFA-DGGTYLGHFENGLFNGFGVLTFSDGSR 61
Query: 202 CWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEG 240
YEG++ Q G G+ +EG++++ G G
Sbjct: 62 --YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFG 98
>gi|30520314 MORN repeat containing 4 [Homo sapiens]
Length = 146
Score = 63.9 bits (154), Expect = 6e-10
Identities = 39/123 (31%), Positives = 58/123 (47%), Gaps = 15/123 (12%)
Query: 221 YKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPL 280
Y SG Y G+W++ RHG G++ + Y G +E G+ NGFG T +
Sbjct: 10 YSSGEEYRGEWKEGRRHGFGQLMF-ADGGTYLGHFENGLFNGFGVLT----------FSD 58
Query: 281 RNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR----VYEGAFSN 336
+ Y GEF G +G G F ++GE+ + + G G LTF +G EG F N
Sbjct: 59 GSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFEN 118
Query: 337 DHI 339
+ +
Sbjct: 119 NKL 121
Score = 63.9 bits (154), Expect = 6e-10
Identities = 34/86 (39%), Positives = 44/86 (51%)
Query: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
E Y GE G G G F G TY G F GL +G G ++DG +YEG+F +
Sbjct: 14 EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNG 73
Query: 144 HGVYTWPDGSMYEGEVVNGMRNGFGM 169
GV+ D +EGE NG +GFG+
Sbjct: 74 VGVFIRYDNMTFEGEFKNGRVDGFGL 99
Score = 63.2 bits (152), Expect = 1e-09
Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 1/99 (1%)
Query: 98 EGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEG 157
+G + G YRG + EG HG G ++ADG Y G F + GV T+ DGS YEG
Sbjct: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEG 64
Query: 158 EVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYY 196
E G NG G+F +++ G + NG+ G G + +
Sbjct: 65 EFAQGKFNGVGVF-IRYDNMTFEGEFKNGRVDGFGLLTF 102
Score = 58.2 bits (139), Expect = 3e-08
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 10/97 (10%)
Query: 246 TTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGA 305
++ EEY G W+ G ++GFG + Y+G F NG +G G ++ G+
Sbjct: 11 SSGEEYRGEWKEGRRHGFG----------QLMFADGGTYLGHFENGLFNGFGVLTFSDGS 60
Query: 306 MYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Y+GE+ K +G+G + +EG F N + GF
Sbjct: 61 RYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97
Score = 52.8 bits (125), Expect = 1e-06
Identities = 25/69 (36%), Positives = 36/69 (52%)
Query: 85 SYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH 144
+Y G GL+ G G F G Y G F++G +G G +I D + +EG+F
Sbjct: 38 TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97
Query: 145 GVYTWPDGS 153
G+ T+PDGS
Sbjct: 98 GLLTFPDGS 106
Score = 50.1 bits (118), Expect = 9e-06
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 275 SSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAF 334
S Y EY GE+ G RHG G+ +A G Y G + + +G G LTF +G YEG F
Sbjct: 7 SFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEF 66
Query: 335 SNDHIAG 341
+ G
Sbjct: 67 AQGKFNG 73
Score = 49.3 bits (116), Expect = 2e-05
Identities = 21/47 (44%), Positives = 27/47 (57%)
Query: 296 RGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
+G F Y+SG Y GEW ++HG G+L F +G Y G F N GF
Sbjct: 5 KGSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGF 51
Score = 46.6 bits (109), Expect = 1e-04
Identities = 28/99 (28%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Query: 142 MNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGT 201
+ G +T+ G Y GE G R+GFG + +Y+GH+ NG +G G + ++
Sbjct: 3 LTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFA-DGGTYLGHFENGLFNGFGVLTFSDGSR 61
Query: 202 CWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEG 240
YEG++ Q G G+ +EG++++ G G
Sbjct: 62 --YEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFG 98
>gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]
Length = 129
Score = 62.0 bits (149), Expect = 2e-09
Identities = 44/132 (33%), Positives = 57/132 (43%), Gaps = 19/132 (14%)
Query: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRH 237
+Y G W GK HG G + +G Y G W + G+ + SGN +EG W RH
Sbjct: 13 AYCGGWEGGKAHGHG-LCTGPKGQGEYSGSWNFGFEVA-GVYTWPSGNTFEGYWSQGKRH 70
Query: 238 GEG---RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRH 294
G G + RWL Y G W G + +G IR S +Y G + NG +
Sbjct: 71 GLGIETKGRWL-----YKGEWTHGFKGRYG--------IRQSSSS-GAKYEGTWNNGLQD 116
Query: 295 GRGKFYYASGAM 306
G G YA G M
Sbjct: 117 GYGTETYADGGM 128
Score = 57.0 bits (136), Expect = 7e-08
Identities = 38/127 (29%), Positives = 55/127 (43%), Gaps = 9/127 (7%)
Query: 103 FQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNH---GVYTWPDGSMYEGEV 159
F G Y G + G HG G G K +G++ + GVYTWP G+ +EG
Sbjct: 8 FDDGGAYCGGWEGGKAHGHGL---CTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYW 64
Query: 160 VNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIR 219
G R+G G+ Y G W +G + G+ I + YEG W ++ G+G
Sbjct: 65 SQGKRHGLGIETKGRW--LYKGEWTHGFK-GRYGIRQSSSSGAKYEGTWNNGLQDGYGTE 121
Query: 220 CYKSGNI 226
Y G +
Sbjct: 122 TYADGGM 128
Score = 52.0 bits (123), Expect = 2e-06
Identities = 36/117 (30%), Positives = 47/117 (40%), Gaps = 13/117 (11%)
Query: 221 YKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPL 280
+ G Y G WE HG G EY+G W G + G +TW P
Sbjct: 8 FDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVA-GVYTW----------PS 56
Query: 281 RNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMG-RLTFKNGRVYEGAFSN 336
N + G + G RHG G +Y GEW K G R + +G YEG ++N
Sbjct: 57 GNTFEGYWSQGKRHGLG-IETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNN 112
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 32/123 (26%)
Query: 88 GEKVRGLYEGE--------GFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKN 139
G K +G Y G G + G T+ G +S+G HG G++ +G +
Sbjct: 31 GPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGL-------GIETKGRW--- 80
Query: 140 VPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQE 199
+Y+GE +G + +G+ + S+ Y G W NG + G G+ Y
Sbjct: 81 --------------LYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADG 126
Query: 200 GTC 202
G C
Sbjct: 127 GMC 129
>gi|75750531 ankyrin repeat and MYND domain containing 1 isoform 2
[Homo sapiens]
Length = 717
Score = 57.4 bits (137), Expect = 6e-08
Identities = 26/78 (33%), Positives = 36/78 (46%)
Query: 98 EGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEG 157
+G +Q GC Y+G F + G G + W G Y G F ++ G Y WPDGS + G
Sbjct: 80 QGVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTG 139
Query: 158 EVVNGMRNGFGMFKCSTQ 175
R G+G T+
Sbjct: 140 TFYLSHREGYGTMYMKTR 157
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 11/84 (13%)
Query: 217 GIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSS 276
G++ ++ G +Y+G++ NM+ G G+ W T E Y G++ R +G GT+ W
Sbjct: 81 GVQEWQDGCMYQGEFGLNMKLGYGKFSW-PTGESYHGQFYRDHCHGLGTYMW-------- 131
Query: 277 QYPLRNEYIGEFVNGYRHGRGKFY 300
P + + G F +R G G Y
Sbjct: 132 --PDGSSFTGTFYLSHREGYGTMY 153
Score = 44.3 bits (103), Expect = 5e-04
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 16/136 (11%)
Query: 3 KEKKKADKKGEK-SARSPSSLSDNLDFSKQDGNTT-RQEMSPAGVPLLGMQLNEVKPKKD 60
+++ K GE +A P SL + F+ +D + +E A PL L E
Sbjct: 20 RQRPLEGKGGETPAAEEPGSLKNYAVFATRDVSAAPEKEEEEAEGPLRAQDLRE------ 73
Query: 61 RQNVQQNEDASQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHG 120
+Q + ++++ + Y+GE + G G ++ G +Y G F HG
Sbjct: 74 -SYIQLVQGVQEWQDGCM-------YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHG 125
Query: 121 QGTYIWADGLKYEGDF 136
GTY+W DG + G F
Sbjct: 126 LGTYMWPDGSSFTGTF 141
Score = 41.2 bits (95), Expect = 0.004
Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Query: 198 QEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWER 257
Q+G C Y+G++ N+K G+G + +G Y GQ+ + HG G W +TG +
Sbjct: 86 QDG-CMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMW-PDGSSFTGTFYL 143
Query: 258 GIQNGFGT 265
+ G+GT
Sbjct: 144 SHREGYGT 151
Score = 40.4 bits (93), Expect = 0.007
Identities = 19/59 (32%), Positives = 30/59 (50%)
Query: 284 YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Y GEF + G GKF + +G Y G++ + HG+G + +G + G F H G+
Sbjct: 91 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGY 149
Score = 40.0 bits (92), Expect = 0.009
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 140 VPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQE 199
+ + GV W DG MY+GE M+ G+G F T SY G + HG G+ Y +
Sbjct: 76 IQLVQGVQEWQDGCMYQGEFGLNMKLGYGKFSWPTGE-SYHGQFYRDHCHGLGT-YMWPD 133
Query: 200 GTCWYEGDWVQNIKKGWGIRCYKS 223
G+ + G + + ++G+G K+
Sbjct: 134 GSS-FTGTFYLSHREGYGTMYMKT 156
Score = 38.5 bits (88), Expect = 0.027
Identities = 23/104 (22%), Positives = 43/104 (41%), Gaps = 11/104 (10%)
Query: 251 YTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGE 310
Y G + ++ G+G +W P Y G+F + HG G + + G+ + G
Sbjct: 91 YQGEFGLNMKLGYGKFSW----------PTGESYHGQFYRDHCHGLGTYMWPDGSSFTGT 140
Query: 311 WVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFPDLEVEFISCLD 354
+ + + G G + K R+++ ND + D + C D
Sbjct: 141 FYLSHREGYGTMYMKT-RLFQTHCHNDIVNLLLDCGADVNKCSD 183
Score = 38.1 bits (87), Expect = 0.036
Identities = 22/62 (35%), Positives = 29/62 (46%), Gaps = 7/62 (11%)
Query: 280 LRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHI 339
LR YI + V G + + G MY GE+ N K G G+ ++ G Y G F DH
Sbjct: 71 LRESYI-QLVQGVQE------WQDGCMYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHC 123
Query: 340 AG 341
G
Sbjct: 124 HG 125
>gi|18139549 SET domain-containing protein 7 [Homo sapiens]
Length = 366
Score = 54.7 bits (130), Expect = 4e-07
Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
Query: 80 KLIVESYEGE-KVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVK 138
+++ E+ EG GL G + + G F G +G+G + + DG EG +V
Sbjct: 6 EMVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVD 65
Query: 139 NVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQ 198
+ GVYT+ DG + +G V+G NG + + + G + + RHG IYY
Sbjct: 66 DALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDTDGRLIFKGQYKDNIRHGVCWIYYPD 125
Query: 199 EGT 201
G+
Sbjct: 126 GGS 128
Score = 50.1 bits (118), Expect = 9e-06
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 10/84 (11%)
Query: 258 GIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKH 317
G+ +GF T T Y + + G FV+G ++GRGKF++ G+ +G +V +
Sbjct: 20 GLPHGFCTVT----------YSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQ 69
Query: 318 GMGRLTFKNGRVYEGAFSNDHIAG 341
G G T+++G V +G + + + G
Sbjct: 70 GQGVYTYEDGGVLQGTYVDGELNG 93
Score = 34.7 bits (78), Expect = 0.39
Identities = 16/52 (30%), Positives = 28/52 (53%)
Query: 290 NGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
+G HG Y+S ++G +V +K+G G+ F +G EG + +D + G
Sbjct: 19 DGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQG 70
Score = 32.7 bits (73), Expect = 1.5
Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 22/131 (16%)
Query: 185 NGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRW 244
+G HG ++ Y+ T +EG++V K G G + G+ EG + D+ G+G
Sbjct: 19 DGLPHGFCTVTYSS--TDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQG---- 72
Query: 245 LTTNEE---YTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYI--GEFVNGYRHGRGKF 299
+ T E+ G + G NG + +Y I G++ + RHG
Sbjct: 73 VYTYEDGGVLQGTYVDGELNG-----------PAQEYDTDGRLIFKGQYKDNIRHGVCWI 121
Query: 300 YYASGAMYDGE 310
YY G GE
Sbjct: 122 YYPDGGSLVGE 132
>gi|75750529 ankyrin repeat and MYND domain containing 1 isoform 1
[Homo sapiens]
Length = 941
Score = 50.4 bits (119), Expect = 7e-06
Identities = 40/160 (25%), Positives = 65/160 (40%), Gaps = 20/160 (12%)
Query: 109 YRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFG 168
Y+G F + G G + W G Y G F ++ G Y WPDGS + G R G+G
Sbjct: 2 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYG 61
Query: 169 MFKCSTQPVSYIGHWCNGKRHGKGSIYY---NQEGTCWYEGDWVQ---NIKKGWGIRCYK 222
T+ + G + +R G G Y +Q+ W+ ++ I G+ + Y
Sbjct: 62 TMYMKTR--LFQGLYKADQRFGPGVETYPDGSQDVGLWFREQLIKLCTQIPSGFSLLRYP 119
Query: 223 SGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNG 262
++ + H R ++ +EE W G+Q G
Sbjct: 120 -------EFSSFITHSPAR---ISLSEEEKTEW--GLQEG 147
Score = 47.0 bits (110), Expect = 8e-05
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 12/102 (11%)
Query: 226 IYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYI 285
+Y+G++ NM+ G G+ W T E Y G++ R +G GT+ W P + +
Sbjct: 1 MYQGEFGLNMKLGYGKFSW-PTGESYHGQFYRDHCHGLGTYMW----------PDGSSFT 49
Query: 286 GEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNG 327
G F +R G G Y + ++ G + ++++ G G T+ +G
Sbjct: 50 GTFYLSHREGYGTMYMKT-RLFQGLYKADQRFGPGVETYPDG 90
Score = 40.4 bits (93), Expect = 0.007
Identities = 19/59 (32%), Positives = 30/59 (50%)
Query: 284 YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Y GEF + G GKF + +G Y G++ + HG+G + +G + G F H G+
Sbjct: 2 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGY 60
Score = 40.0 bits (92), Expect = 0.009
Identities = 19/51 (37%), Positives = 26/51 (50%)
Query: 86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDF 136
Y+GE + G G ++ G +Y G F HG GTY+W DG + G F
Sbjct: 2 YQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTF 52
Score = 39.7 bits (91), Expect = 0.012
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 11/91 (12%)
Query: 251 YTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRHGRGKFYYASGAMYDGE 310
Y G + ++ G+G +W P Y G+F + HG G + + G+ + G
Sbjct: 2 YQGEFGLNMKLGYGKFSW----------PTGESYHGQFYRDHCHGLGTYMWPDGSSFTGT 51
Query: 311 WVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
+ + + G G + K R+++G + D G
Sbjct: 52 FYLSHREGYGTMYMKT-RLFQGLYKADQRFG 81
Score = 35.0 bits (79), Expect = 0.30
Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 154 MYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIK 213
MY+GE M+ G+G F T SY G + HG G+ Y +G+ + G + + +
Sbjct: 1 MYQGEFGLNMKLGYGKFSWPTGE-SYHGQFYRDHCHGLGT-YMWPDGSS-FTGTFYLSHR 57
Query: 214 KGWGIRCYKSGNIYEGQWEDNMRHGEG 240
+G+G Y +++G ++ + R G G
Sbjct: 58 EGYG-TMYMKTRLFQGLYKADQRFGPG 83
Score = 34.3 bits (77), Expect = 0.52
Identities = 15/36 (41%), Positives = 19/36 (52%)
Query: 306 MYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
MY GE+ N K G G+ ++ G Y G F DH G
Sbjct: 1 MYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHG 36
Score = 33.1 bits (74), Expect = 1.1
Identities = 23/74 (31%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query: 84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMN 143
ESY G+ R G G + G ++ G F G GT L ++G + +
Sbjct: 23 ESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYGTMYMKTRL-FQGLYKADQRFG 81
Query: 144 HGVYTWPDGSMYEG 157
GV T+PDGS G
Sbjct: 82 PGVETYPDGSQDVG 95
>gi|224282170 MORN repeat containing 2 [Homo sapiens]
Length = 79
Score = 46.2 bits (108), Expect = 1e-04
Identities = 19/48 (39%), Positives = 30/48 (62%)
Query: 294 HGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
+G G+ + SGA+Y+G++ N HG+G TF NG Y G F+ + + G
Sbjct: 2 NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEG 49
Score = 44.7 bits (104), Expect = 4e-04
Identities = 20/52 (38%), Positives = 27/52 (51%)
Query: 106 GCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEG 157
G Y G F + + HG GTY + +G KY G+F +N G YT G + G
Sbjct: 12 GAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEWSG 63
Score = 40.8 bits (94), Expect = 0.006
Identities = 18/51 (35%), Positives = 27/51 (52%)
Query: 86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDF 136
YEG+ ++ G G F G Y G F+E + G+G Y GL++ G+F
Sbjct: 15 YEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEWSGNF 65
Score = 40.4 bits (93), Expect = 0.007
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Query: 284 YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGFP 343
Y G+F + HG G + + +GA Y G + N+ G G T G + G F H P
Sbjct: 15 YEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGLEWSGNF---HFTAAP 71
Query: 344 DLEVE 348
DL+++
Sbjct: 72 DLKLK 76
Score = 37.0 bits (84), Expect = 0.079
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Query: 215 GWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGFGTHT 267
G+G + SG +YEGQ++DNM HG G + +YTG + G G +T
Sbjct: 3 GFGRLEHFSGAVYEGQFKDNMFHGLGTYTF-PNGAKYTGNFNENRVEGEGEYT 54
Score = 33.5 bits (75), Expect = 0.88
Identities = 18/53 (33%), Positives = 24/53 (45%)
Query: 118 MHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMF 170
M+G G G YEG F N+ G YT+P+G+ Y G G G +
Sbjct: 1 MNGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEGEY 53
>gi|223278407 MORN repeat containing 5 [Homo sapiens]
Length = 161
Score = 42.7 bits (99), Expect = 0.001
Identities = 19/55 (34%), Positives = 30/55 (54%)
Query: 282 NEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSN 336
++YIGE+V+G G+ K+ + +Y GE HG G L F +G Y+ + N
Sbjct: 6 SKYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYDAIWEN 60
Score = 40.8 bits (94), Expect = 0.006
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHG 145
Y GE V G EG+ Y G +G+ HG+GT + G +Y+ + + + G
Sbjct: 8 YIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYDAIWENGLAIK-G 66
Query: 146 VYTWPDGSMYE 156
YT+ DG Y+
Sbjct: 67 TYTFSDGLHYD 77
Score = 40.8 bits (94), Expect = 0.006
Identities = 20/53 (37%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 279 PLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYE 331
P Y+GE +G HG G Y+ SG+ YD W N G TF +G Y+
Sbjct: 26 PTETIYVGEMKDGMFHGEGTLYFPSGSQYDAIW-ENGLAIKGTYTFSDGLHYD 77
Score = 35.8 bits (81), Expect = 0.18
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Query: 152 GSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYY---NQEGTCWYEG 206
GS Y GE V+G G + T+ + Y+G +G HG+G++Y+ +Q W G
Sbjct: 5 GSKYIGEYVDGRMEGKAKYILPTETI-YVGEMKDGMFHGEGTLYFPSGSQYDAIWENG 61
Score = 35.4 bits (80), Expect = 0.23
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 204 YEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNEEYTGRWERGIQNGF 263
Y G++V +G + IY G+ +D M HGEG + + + +Y WE G+
Sbjct: 8 YIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTL-YFPSGSQYDAIWENGLAIK- 65
Query: 264 GTHTW 268
GT+T+
Sbjct: 66 GTYTF 70
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/82 (26%), Positives = 32/82 (39%), Gaps = 1/82 (1%)
Query: 106 GCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMR- 164
G Y G + +G M G+ YI Y G+ + G +P GS Y+ NG+
Sbjct: 5 GSKYIGEYVDGRMEGKAKYILPTETIYVGEMKDGMFHGEGTLYFPSGSQYDAIWENGLAI 64
Query: 165 NGFGMFKCSTQPVSYIGHWCNG 186
G F H+C+G
Sbjct: 65 KGTYTFSDGLHYDEKNWHYCDG 86
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 37.0 bits (84), Expect = 0.079
Identities = 43/179 (24%), Positives = 74/179 (41%), Gaps = 37/179 (20%)
Query: 705 DVNKIRKSEPKIKKSVSHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNN 764
DV KI+K E +++K+ +H R N++ GK R +D EE+ +
Sbjct: 922 DVEKIQKLEAELEKAATHRR----NYEEKGK-------------RYRDAVEEKLAKLQKH 964
Query: 765 TYVFFVNTLFHAYKREEAIKEKIRADRLRSTAQAQQRKMEDD-ELEARLNIFILREEEAK 823
N+ K + +K + + + L+ +++ DD + E R + + + E K
Sbjct: 965 ------NSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELK 1018
Query: 824 RHDYEVDITVLKEPAD------------VSSSHLILDPPKEDVT-VSPSSKTITSKKKK 869
DYE I LKE V H+ D K +V +S KTI+ +K+
Sbjct: 1019 TQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKE 1077
>gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]
Length = 292
Score = 35.4 bits (80), Expect = 0.23
Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 675 KSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKI--RKSEPKIKKSVSHERVSKMNFKL 732
K P+ + ES+ +HSD + SSSS+ D K +K E K SV++ + + K
Sbjct: 215 KKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKR 274
Query: 733 TGKGITFFSSESKKYERPKDD 753
T + +++ + E +DD
Sbjct: 275 TNWKV---ATDERSAESSEDD 292
>gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]
Length = 293
Score = 35.4 bits (80), Expect = 0.23
Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 675 KSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKI--RKSEPKIKKSVSHERVSKMNFKL 732
K P+ + ES+ +HSD + SSSS+ D K +K E K SV++ + + K
Sbjct: 216 KKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKR 275
Query: 733 TGKGITFFSSESKKYERPKDD 753
T + +++ + E +DD
Sbjct: 276 TNWKV---ATDERSAESSEDD 293
>gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens]
Length = 293
Score = 35.4 bits (80), Expect = 0.23
Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 675 KSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKI--RKSEPKIKKSVSHERVSKMNFKL 732
K P+ + ES+ +HSD + SSSS+ D K +K E K SV++ + + K
Sbjct: 216 KKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKR 275
Query: 733 TGKGITFFSSESKKYERPKDD 753
T + +++ + E +DD
Sbjct: 276 TNWKV---ATDERSAESSEDD 293
>gi|37694065 estrogen receptor binding site associated antigen 9
[Homo sapiens]
Length = 213
Score = 33.9 bits (76), Expect = 0.67
Identities = 39/171 (22%), Positives = 76/171 (44%), Gaps = 18/171 (10%)
Query: 640 VTDQMTKSYTNVPAD-DVSGNKHETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSS 698
+T T Y++VP DV +T ++DA P++V + + + + A +S
Sbjct: 40 ITLPTTVDYSSVPKQTDVEE------WTSWDEDA----PTSV---KIEGGNGNVATQQNS 86
Query: 699 KLELSPDVNKIRKSEPKIKKSVSHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEF 758
+L PD K + + + ++ +NF + F S + + P + E
Sbjct: 87 LEQLEPDYFKDMTPTIRKTQKIVIKKREPLNFGIPDGSTGFSSRLAATQDLPFIHQSSEL 146
Query: 759 ---NTWVNNTYVFFVNTLFHAYKREEAIKEKIRADRLRSTAQAQQRKMEDD 806
+TW NT + A++ EE ++++ ADR + A+ Q++KME +
Sbjct: 147 GDLDTWQENTNAWEEEE-DAAWQAEEVLRQQKLADREKRAAEQQRKKMEKE 196
>gi|4758230 estrogen receptor binding site associated antigen 9
[Homo sapiens]
Length = 213
Score = 33.9 bits (76), Expect = 0.67
Identities = 39/171 (22%), Positives = 76/171 (44%), Gaps = 18/171 (10%)
Query: 640 VTDQMTKSYTNVPAD-DVSGNKHETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSS 698
+T T Y++VP DV +T ++DA P++V + + + + A +S
Sbjct: 40 ITLPTTVDYSSVPKQTDVEE------WTSWDEDA----PTSV---KIEGGNGNVATQQNS 86
Query: 699 KLELSPDVNKIRKSEPKIKKSVSHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEF 758
+L PD K + + + ++ +NF + F S + + P + E
Sbjct: 87 LEQLEPDYFKDMTPTIRKTQKIVIKKREPLNFGIPDGSTGFSSRLAATQDLPFIHQSSEL 146
Query: 759 ---NTWVNNTYVFFVNTLFHAYKREEAIKEKIRADRLRSTAQAQQRKMEDD 806
+TW NT + A++ EE ++++ ADR + A+ Q++KME +
Sbjct: 147 GDLDTWQENTNAWEEEE-DAAWQAEEVLRQQKLADREKRAAEQQRKKMEKE 196
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
[Homo sapiens]
Length = 3969
Score = 33.1 bits (74), Expect = 1.1
Identities = 45/210 (21%), Positives = 80/210 (38%), Gaps = 13/210 (6%)
Query: 667 ILNQDAQNKSPSAVMSHESDAAHSDSARSSS-SKLELSPDVNKIRKSEPKIKKSVSHERV 725
+ N+ + K S + S +HS RS S ELSP + + SVS
Sbjct: 731 VSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSP-LTPPSSVSSSLSISVSPLAT 789
Query: 726 SKMN--FKLTGKGITFFSSESKKYERPKDDREEEFNTWVNNTYV-----FFVNTLFHAYK 778
S +N F +T ++K +RP+ + +++ F + +
Sbjct: 790 SALNPTFTFPSHSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGR 849
Query: 779 REEAIKEKIRADRLRSTAQAQQRKMEDDELEARLNIFILREEEAKRHDYEVDITVLKEPA 838
++ E++ DR + + + E D + N R+E+ K+ + L
Sbjct: 850 NKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVG 909
Query: 839 DVSSSHLILDPPKEDVTVSPSSKTITSKKK 868
VS ++ EDV S S+K T +KK
Sbjct: 910 RVSKEKVV----GEDVATSSSAKKATGRKK 935
>gi|155030242 WD repeat domain 60 [Homo sapiens]
Length = 1066
Score = 32.7 bits (73), Expect = 1.5
Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 6/110 (5%)
Query: 684 ESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSVSHERVSKMNFKLTGK-GITFFSS 742
+ D S + S KLE P K E + + +ER+ +++ KL K G T F
Sbjct: 389 DGDDDESSNEPESREKLEELPLAQKKEIQEIQRAINAENERIGELSLKLFQKRGRTEFEK 448
Query: 743 ESKKYERPKDDREEEFNTWVNNTYVFFVNTLFHAYKREEAIKEKIRADRL 792
E + D V +V F + R +A+K+K+R+ +L
Sbjct: 449 EPR-----TDTNSSPSRASVCGIFVDFASASHRQKSRTQALKQKMRSTKL 493
>gi|122937227 U2-associated SR140 protein [Homo sapiens]
Length = 1029
Score = 32.7 bits (73), Expect = 1.5
Identities = 17/55 (30%), Positives = 29/55 (52%)
Query: 673 QNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVNKIRKSEPKIKKSVSHERVSK 727
++ SP + S S+ +H +S+RS SS + DV+K K P ++ R S+
Sbjct: 945 KSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSR 999
>gi|21264343 scaffold attachment factor B [Homo sapiens]
Length = 915
Score = 32.3 bits (72), Expect = 2.0
Identities = 43/179 (24%), Positives = 71/179 (39%), Gaps = 29/179 (16%)
Query: 654 DDVSGNKHETIYTILNQDAQNKSPSAVMSHESDAAHSDSARSSSSKLELSPDVN------ 707
DD SG K + +QD Q PS + K + P ++
Sbjct: 529 DDGSGEKSK------DQDDQKPGPSERSRATKSGSRGTERTVVMDKSKGVPVISVKTSGS 582
Query: 708 KIRKSEPKIKKSVSHERVSKMNFKLTGKGITFFSSESKKYERPKDDREEEFNTWVNNTYV 767
K R S+ + +KS S E+ S ++F + SES R + +RE+
Sbjct: 583 KERASKSQDRKSASREKRSVVSFDKVKEPRKSRDSESHSRVRERSEREQRMQA------- 635
Query: 768 FFVNTLFHAYKREEAIKEKIRADRLRSTAQAQQR-KMEDDELE-ARLNIFILREEEAKR 824
++REE + +I +RL Q +R +ME + LE R+++ R E +R
Sbjct: 636 --------QWEREERERLEIARERLAFQRQRLERERMERERLERERMHVEHERRREQER 686
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,780,488
Number of Sequences: 37866
Number of extensions: 1577844
Number of successful extensions: 5295
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 4738
Number of HSP's gapped (non-prelim): 283
length of query: 870
length of database: 18,247,518
effective HSP length: 111
effective length of query: 759
effective length of database: 14,044,392
effective search space: 10659693528
effective search space used: 10659693528
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.