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Search of human proteins with 153791535
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153791535 general control of amino acid synthesis 5-like 2
[Homo sapiens]
(837 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153791535 general control of amino acid synthesis 5-like 2 [H... 1704 0.0
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 1174 0.0
gi|38788260 bromodomain PHD finger transcription factor isoform ... 109 9e-24
gi|38788274 bromodomain PHD finger transcription factor isoform ... 109 9e-24
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 95 3e-19
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 77 5e-14
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 77 5e-14
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 75 2e-13
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 75 2e-13
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens] 74 6e-13
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens] 74 6e-13
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 74 6e-13
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 74 6e-13
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa... 73 1e-12
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 72 2e-12
gi|164419758 bromodomain containing 2 [Homo sapiens] 71 4e-12
gi|4826806 bromodomain containing 2 [Homo sapiens] 71 4e-12
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 70 8e-12
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 70 8e-12
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 70 8e-12
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 68 4e-11
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 66 1e-10
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 65 2e-10
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 65 2e-10
gi|4503519 eukaryotic translation initiation factor 3, subunit 5... 62 2e-09
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 61 4e-09
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 60 6e-09
gi|30794372 polybromo 1 isoform 1 [Homo sapiens] 59 1e-08
gi|93102371 polybromo 1 isoform 2 [Homo sapiens] 59 1e-08
gi|41281917 polybromo 1 isoform 4 [Homo sapiens] 59 1e-08
>gi|153791535 general control of amino acid synthesis 5-like 2 [Homo
sapiens]
Length = 837
Score = 1704 bits (4412), Expect = 0.0
Identities = 837/837 (100%), Positives = 837/837 (100%)
Query: 1 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT 60
MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT
Sbjct: 1 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT 60
Query: 61 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC 120
GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC
Sbjct: 61 GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC 120
Query: 121 NGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVE 180
NGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVE
Sbjct: 121 NGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVE 180
Query: 181 NLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQ 240
NLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQ
Sbjct: 181 NLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQ 240
Query: 241 YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCH 300
YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCH
Sbjct: 241 YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCH 300
Query: 301 VPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFL 360
VPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFL
Sbjct: 301 VPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFL 360
Query: 361 SMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLS 420
SMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLS
Sbjct: 361 SMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLS 420
Query: 421 LDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLL 480
LDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLL
Sbjct: 421 LDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLL 480
Query: 481 SANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIA 540
SANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIA
Sbjct: 481 SANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIA 540
Query: 541 RLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE 600
RLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE
Sbjct: 541 RLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE 600
Query: 601 YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIP 660
YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIP
Sbjct: 601 YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIP 660
Query: 661 YTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLG 720
YTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLG
Sbjct: 661 YTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLG 720
Query: 721 KEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTE 780
KEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTE
Sbjct: 721 KEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTE 780
Query: 781 RLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK 837
RLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK
Sbjct: 781 RLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK 837
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 1174 bits (3038), Expect = 0.0
Identities = 586/813 (72%), Positives = 667/813 (82%), Gaps = 14/813 (1%)
Query: 32 PSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPARPGLSQQQRASQRK 91
P PA+ P P P P +P AA AG +G GP AG+ P G + R + +K
Sbjct: 27 PQPAALP---PAP-PQGSPCAAAAGGSGACGPATAVAAAGTAEGPGGGGSA---RIAVKK 79
Query: 92 AQVRGLPRAKKLEKLGVFSACKANETCKCNGWKNPKP-PTAPRMDLQQPAANLSELCRSC 150
AQ+R PRAKKLEKLGV+SACKA E+CKCNGWKNP P PT PR DLQQ +L+E CRSC
Sbjct: 80 AQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRADLQQIIVSLTESCRSC 139
Query: 151 EHPLADHVSHLENVSEDEINRLLGMVVDVENLFMSVHKEEDTDTKQVYFYLFKLLRKCIL 210
H LA HVSHLENVSE+E+NRLLG+V+DVE LF VHKEED DTKQVYFYLFKLLRK IL
Sbjct: 140 SHALAAHVSHLENVSEEEMNRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSIL 199
Query: 211 QMTRPVVEGSL-GSPPFEKPNIEQGVLNFVQYKFSHLAPRERQTMFELSKMFLLCLNYWK 269
Q +PVVEGSL PPFEKP+IEQGV NFVQYKFSHL +ERQT+ EL+KMFL +NYW
Sbjct: 200 QRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPAKERQTIVELAKMFLNRINYWH 259
Query: 270 LETPAQFRQRSQAEDVATYKVNYTRWLCYCHVPQSCDSLPRYETTHVFGRSLLRSIFTVT 329
LE P+Q R RS +D++ YK NYTRWLCYC+VPQ CDSLPRYETT VFGR+LLRS+FTV
Sbjct: 260 LEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTQVFGRTLLRSVFTVM 319
Query: 330 RRQLLEKFRVEKDKLVPEKRTLILTHFPKFLSMLEEEIYGANSPIWESGFTMPPSE---- 385
RRQLLE+ R EKDKL EKRTLILTHFPKFLSMLEEE+Y NSPIW+ F S
Sbjct: 320 RRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSQL 379
Query: 386 GTQLVPRPASVSAAV-VPSTPIFSPSMGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLED 444
G Q V P V+ + ST GS+S S+G E PGEKR + ++ LE+
Sbjct: 380 GIQTVINPPPVAGTISYNSTSSSLEQPNAGSSSPACKASSGLEANPGEKRKMTDSHVLEE 439
Query: 445 AKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLLSANAARDETARLEERRGIIEFHVI 504
AK+ RVMGDIPMEL+NEVM TITDPAAMLGPET+ LSA++ARDE ARLEERRG+IEFHV+
Sbjct: 440 AKKPRVMGDIPMELINEVMSTITDPAAMLGPETNFLSAHSARDEAARLEERRGVIEFHVV 499
Query: 505 GNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIARLVFDPKHKTLALIKDGRVIGGIC 564
GNSL K N+++L+WLVGLQNVFSHQLPRMPKEYI RLVFDPKHKTLALIKDGRVIGGIC
Sbjct: 500 GNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGIC 559
Query: 565 FRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKK 624
FRMFP+QGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKH+IL FLTYADEYAIGYFKK
Sbjct: 560 FRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHDILNFLTYADEYAIGYFKK 619
Query: 625 QGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQA 684
QGFSK+IK+PK++Y+GYIKDYEGATLM CELNPRIPYTE S IIKKQKEIIKKLIERKQA
Sbjct: 620 QGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPRIPYTEFSVIIKKQKEIIKKLIERKQA 679
Query: 685 QIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQI 744
QIRKVYPGLSCFK+GVRQIP+ES+PGIRETGWKP GKEK KE +DPDQLY+TLK++L Q+
Sbjct: 680 QIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPRDPDQLYSTLKSILQQV 739
Query: 745 KSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANC 804
KSH SAWPFMEPVK++EAP YYEVIRFP+DLKTM+ERL++RYYV++KLF+ADLQRV NC
Sbjct: 740 KSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNC 799
Query: 805 REYNPPDSEYCRCASALEKFFYFKLKEGGLIDK 837
+EYNPP+SEY +CA+ LEKFF+ K+KE GLIDK
Sbjct: 800 KEYNPPESEYYKCANILEKFFFSKIKEAGLIDK 832
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 109 bits (273), Expect = 9e-24
Identities = 50/97 (51%), Positives = 66/97 (68%)
Query: 734 YTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLF 793
Y LK +L +++H AWPF+EPV ++APDYY VI+ P+DL TM ER++ RYY F
Sbjct: 2790 YEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEF 2849
Query: 794 VADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLK 830
VAD+ ++ NCR YNP DS + +CA LE FF KLK
Sbjct: 2850 VADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2886
Score = 37.7 bits (86), Expect = 0.045
Identities = 33/110 (30%), Positives = 36/110 (32%), Gaps = 43/110 (39%)
Query: 8 PTPAPAAQPRPLQSPAPAPTPTPAPSPASAPI---------------------------- 39
P PAA +PAP P P P P S PI
Sbjct: 8 PPKQPAAPAAERCAPAPPPPPPP---PTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRL 64
Query: 40 -----------PTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPAR 78
P P PAP +AP G G GG G +GG G GG AR
Sbjct: 65 SSPRGGSSSRRKPPPPPPAPPSTSAP-GRGGRGGGGGRTGGGGGGGHLAR 113
Score = 32.7 bits (73), Expect = 1.4
Identities = 14/25 (56%), Positives = 15/25 (60%)
Query: 23 APAPTPTPAPSPASAPIPTPTPAPA 47
AP P TPAP AP P+P P PA
Sbjct: 2651 APCPPVTPAPPAPPAPPPSPPPPPA 2675
Score = 32.3 bits (72), Expect = 1.9
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 1 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPS-PASAPIPTPT 43
+A+ + P P P P PAP P+P P P+ + + TPT
Sbjct: 2643 LAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPT 2686
Score = 32.0 bits (71), Expect = 2.4
Identities = 14/32 (43%), Positives = 16/32 (50%)
Query: 14 AQPRPLQSPAPAPTPTPAPSPASAPIPTPTPA 45
AQ + +P P TP P PA P P P PA
Sbjct: 2644 AQATAVAAPCPPVTPAPPAPPAPPPSPPPPPA 2675
Score = 32.0 bits (71), Expect = 2.4
Identities = 12/25 (48%), Positives = 15/25 (60%)
Query: 25 APTPTPAPSPASAPIPTPTPAPAPA 49
AP P P+P + P P P+P P PA
Sbjct: 2651 APCPPVTPAPPAPPAPPPSPPPPPA 2675
Score = 31.2 bits (69), Expect = 4.2
Identities = 19/65 (29%), Positives = 24/65 (36%), Gaps = 11/65 (16%)
Query: 27 TPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPARPGLSQQQR 86
T AP P P P PAP P+P PA G P P SQ+++
Sbjct: 2647 TAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQ-----------HTGLLSTPTLPAASQKRK 2695
Query: 87 ASQRK 91
+ K
Sbjct: 2696 REEEK 2700
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 109 bits (273), Expect = 9e-24
Identities = 50/97 (51%), Positives = 66/97 (68%)
Query: 734 YTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLF 793
Y LK +L +++H AWPF+EPV ++APDYY VI+ P+DL TM ER++ RYY F
Sbjct: 2807 YEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEF 2866
Query: 794 VADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLK 830
VAD+ ++ NCR YNP DS + +CA LE FF KLK
Sbjct: 2867 VADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLK 2903
Score = 37.7 bits (86), Expect = 0.045
Identities = 33/110 (30%), Positives = 36/110 (32%), Gaps = 43/110 (39%)
Query: 8 PTPAPAAQPRPLQSPAPAPTPTPAPSPASAPI---------------------------- 39
P PAA +PAP P P P P S PI
Sbjct: 8 PPKQPAAPAAERCAPAPPPPPPP---PTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRL 64
Query: 40 -----------PTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPAR 78
P P PAP +AP G G GG G +GG G GG AR
Sbjct: 65 SSPRGGSSSRRKPPPPPPAPPSTSAP-GRGGRGGGGGRTGGGGGGGHLAR 113
Score = 32.7 bits (73), Expect = 1.4
Identities = 14/25 (56%), Positives = 15/25 (60%)
Query: 23 APAPTPTPAPSPASAPIPTPTPAPA 47
AP P TPAP AP P+P P PA
Sbjct: 2668 APCPPVTPAPPAPPAPPPSPPPPPA 2692
Score = 32.3 bits (72), Expect = 1.9
Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 1 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPS-PASAPIPTPT 43
+A+ + P P P P PAP P+P P P+ + + TPT
Sbjct: 2660 LAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPT 2703
Score = 32.0 bits (71), Expect = 2.4
Identities = 14/32 (43%), Positives = 16/32 (50%)
Query: 14 AQPRPLQSPAPAPTPTPAPSPASAPIPTPTPA 45
AQ + +P P TP P PA P P P PA
Sbjct: 2661 AQATAVAAPCPPVTPAPPAPPAPPPSPPPPPA 2692
Score = 32.0 bits (71), Expect = 2.4
Identities = 12/25 (48%), Positives = 15/25 (60%)
Query: 25 APTPTPAPSPASAPIPTPTPAPAPA 49
AP P P+P + P P P+P P PA
Sbjct: 2668 APCPPVTPAPPAPPAPPPSPPPPPA 2692
Score = 31.2 bits (69), Expect = 4.2
Identities = 19/65 (29%), Positives = 24/65 (36%), Gaps = 11/65 (16%)
Query: 27 TPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPARPGLSQQQR 86
T AP P P P PAP P+P PA G P P SQ+++
Sbjct: 2664 TAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQ-----------HTGLLSTPTLPAASQKRK 2712
Query: 87 ASQRK 91
+ K
Sbjct: 2713 REEEK 2717
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 94.7 bits (234), Expect = 3e-19
Identities = 40/106 (37%), Positives = 71/106 (66%)
Query: 721 KEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTE 780
++K K+L + D +T + +L +K+H +WPF+EPV +S AP+YY++I+ P+D+ +M +
Sbjct: 427 EKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEK 486
Query: 781 RLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFY 826
+L Y T++ FV D++ + NCR+YN SEY + + LE+ F+
Sbjct: 487 KLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFH 532
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 77.4 bits (189), Expect = 5e-14
Identities = 40/116 (34%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
Query: 718 PLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVK--KSEAPDYYEVIRFPIDL 775
P K + +QL L+ +L + H AWPF +PV K PDYY++I+ P+D+
Sbjct: 48 PETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDM 107
Query: 776 KTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
T+ +RL + YY + + D + NC YN P + A ALEK F K+ E
Sbjct: 108 GTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE 163
Score = 61.6 bits (148), Expect = 3e-09
Identities = 33/91 (36%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
Query: 737 LKNLLAQIKSHPSAWPFMEPVKKSEAP--DYYEVIRFPIDLKTMTERLRSRYYVTRKLFV 794
LK + A+ K AWPF +PV DY ++I+ P+D+ T+ +L +R Y + F
Sbjct: 361 LKEMFAK-KHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFG 419
Query: 795 ADLQRVIANCREYNPPDSEYCRCASALEKFF 825
AD++ + +NC +YNPPD E A L+ F
Sbjct: 420 ADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 450
Score = 38.1 bits (87), Expect = 0.034
Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 3/39 (7%)
Query: 16 PRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAP 54
P+PLQ+P P P P P P AP P P + P AA P
Sbjct: 244 PQPLQTPPPVP---PQPQPPPAPAPQPVQSHPPIIAATP 279
Score = 37.4 bits (85), Expect = 0.058
Identities = 28/68 (41%), Positives = 30/68 (44%), Gaps = 16/68 (23%)
Query: 4 PSQAPTPAPAAQPRPLQS---PAPAPTP-----TPA-----PSPASAPIPTPT-PAPAPA 49
P Q TP P P P+Q+ P PA TP TP P P P P P P P PA
Sbjct: 205 PPQTQTPQP--NPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPA 262
Query: 50 PAAAPAGS 57
PA P S
Sbjct: 263 PAPQPVQS 270
Score = 35.4 bits (80), Expect = 0.22
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 3/40 (7%)
Query: 3 EPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTP 42
+P Q P P P P+P PAPAP P + P A P P
Sbjct: 245 QPLQTPPPVP---PQPQPPPAPAPQPVQSHPPIIAATPQP 281
Score = 34.3 bits (77), Expect = 0.49
Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 8/58 (13%)
Query: 4 PSQA-PTPAPAAQPRPL-QSPA-----PAPTPTPAPSPASAPIPTPTPAPAPAPAAAP 54
P QA P P PA P + Q+P P P TP P P P P P PAP P + P
Sbjct: 217 PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ-PQPPPAPAPQPVQSHPP 273
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 77.4 bits (189), Expect = 5e-14
Identities = 40/116 (34%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
Query: 718 PLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVK--KSEAPDYYEVIRFPIDL 775
P K + +QL L+ +L + H AWPF +PV K PDYY++I+ P+D+
Sbjct: 48 PETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDM 107
Query: 776 KTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
T+ +RL + YY + + D + NC YN P + A ALEK F K+ E
Sbjct: 108 GTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE 163
Score = 61.6 bits (148), Expect = 3e-09
Identities = 33/91 (36%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
Query: 737 LKNLLAQIKSHPSAWPFMEPVKKSEAP--DYYEVIRFPIDLKTMTERLRSRYYVTRKLFV 794
LK + A+ K AWPF +PV DY ++I+ P+D+ T+ +L +R Y + F
Sbjct: 361 LKEMFAK-KHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFG 419
Query: 795 ADLQRVIANCREYNPPDSEYCRCASALEKFF 825
AD++ + +NC +YNPPD E A L+ F
Sbjct: 420 ADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 450
Score = 40.8 bits (94), Expect = 0.005
Identities = 26/72 (36%), Positives = 29/72 (40%), Gaps = 1/72 (1%)
Query: 6 QAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTP-APAPAPAAAPAGSTGTGGPG 64
QAP P P P P Q P P P P P P P P APA ++P T P
Sbjct: 748 QAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV 807
Query: 65 VGSGGAGSGGDP 76
+ GS DP
Sbjct: 808 LEPQLPGSVFDP 819
Score = 38.1 bits (87), Expect = 0.034
Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 3/39 (7%)
Query: 16 PRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAP 54
P+PLQ+P P P P P P AP P P + P AA P
Sbjct: 244 PQPLQTPPPVP---PQPQPPPAPAPQPVQSHPPIIAATP 279
Score = 37.4 bits (85), Expect = 0.058
Identities = 28/68 (41%), Positives = 30/68 (44%), Gaps = 16/68 (23%)
Query: 4 PSQAPTPAPAAQPRPLQS---PAPAPTP-----TPA-----PSPASAPIPTPT-PAPAPA 49
P Q TP P P P+Q+ P PA TP TP P P P P P P P PA
Sbjct: 205 PPQTQTPQP--NPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPA 262
Query: 50 PAAAPAGS 57
PA P S
Sbjct: 263 PAPQPVQS 270
Score = 36.2 bits (82), Expect = 0.13
Identities = 16/41 (39%), Positives = 18/41 (43%)
Query: 4 PSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTP 44
P P P P+ Q + Q P P P P P P P P P P
Sbjct: 956 PPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRP 996
Score = 35.4 bits (80), Expect = 0.22
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 3/40 (7%)
Query: 3 EPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTP 42
+P Q P P P P+P PAPAP P + P A P P
Sbjct: 245 QPLQTPPPVP---PQPQPPPAPAPQPVQSHPPIIAATPQP 281
Score = 34.3 bits (77), Expect = 0.49
Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 8/58 (13%)
Query: 4 PSQA-PTPAPAAQPRPL-QSPA-----PAPTPTPAPSPASAPIPTPTPAPAPAPAAAP 54
P QA P P PA P + Q+P P P TP P P P P P PAP P + P
Sbjct: 217 PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ-PQPPPAPAPQPVQSHPP 273
Score = 31.6 bits (70), Expect = 3.2
Identities = 19/61 (31%), Positives = 19/61 (31%), Gaps = 14/61 (22%)
Query: 8 PTPAPAAQPRPLQSPAPAPTPT--------------PAPSPASAPIPTPTPAPAPAPAAA 53
P P P QP P Q P P P P P P P P P P A
Sbjct: 976 PPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAK 1035
Query: 54 P 54
P
Sbjct: 1036 P 1036
Score = 30.0 bits (66), Expect = 9.3
Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 4/43 (9%)
Query: 4 PSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAP 46
P Q P P P P+ Q P P P P P A AP +P P
Sbjct: 761 PQQPPPPPP---PQQQQQPPPPPPPPSMPQQA-APAMKSSPPP 799
Score = 30.0 bits (66), Expect = 9.3
Identities = 18/49 (36%), Positives = 19/49 (38%), Gaps = 1/49 (2%)
Query: 6 QAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAP 54
Q PTP + Q P P P P P PS P P P P P P
Sbjct: 939 QPPTPLLPSVKVQSQPPPPLPPP-PHPSVQQQLQQQPPPPPPPQPQPPP 986
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 75.5 bits (184), Expect = 2e-13
Identities = 38/103 (36%), Positives = 55/103 (53%), Gaps = 2/103 (1%)
Query: 731 DQLYTTLKNLLAQIKSHPSAWPFMEPVK--KSEAPDYYEVIRFPIDLKTMTERLRSRYYV 788
+QL K +L + H +WPF PV K + PDYY +I+ P+DL T+ +RL ++YY
Sbjct: 30 NQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYA 89
Query: 789 TRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
+ D + +NC YN P + A ALEK F KL +
Sbjct: 90 KASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQ 132
Score = 63.2 bits (152), Expect = 1e-09
Identities = 34/91 (37%), Positives = 52/91 (57%), Gaps = 3/91 (3%)
Query: 737 LKNLLAQIKSHPSAWPFMEPVKKSEAP--DYYEVIRFPIDLKTMTERLRSRYYVTRKLFV 794
LK +LA+ K AWPF PV + +YY+V++ P+DL T+ E++ ++ Y F
Sbjct: 280 LKEMLAK-KHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFA 338
Query: 795 ADLQRVIANCREYNPPDSEYCRCASALEKFF 825
AD++ + NC +YNPPD E A L+ F
Sbjct: 339 ADVRLMFMNCYKYNPPDHEVVTMARMLQDVF 369
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 75.5 bits (184), Expect = 2e-13
Identities = 38/103 (36%), Positives = 55/103 (53%), Gaps = 2/103 (1%)
Query: 731 DQLYTTLKNLLAQIKSHPSAWPFMEPVK--KSEAPDYYEVIRFPIDLKTMTERLRSRYYV 788
+QL K +L + H +WPF PV K + PDYY +I+ P+DL T+ +RL ++YY
Sbjct: 30 NQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNTIKKRLENKYYA 89
Query: 789 TRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
+ D + +NC YN P + A ALEK F KL +
Sbjct: 90 KASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQKLSQ 132
Score = 63.2 bits (152), Expect = 1e-09
Identities = 34/91 (37%), Positives = 52/91 (57%), Gaps = 3/91 (3%)
Query: 737 LKNLLAQIKSHPSAWPFMEPVKKSEAP--DYYEVIRFPIDLKTMTERLRSRYYVTRKLFV 794
LK +LA+ K AWPF PV + +YY+V++ P+DL T+ E++ ++ Y F
Sbjct: 280 LKEMLAK-KHFSYAWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFA 338
Query: 795 ADLQRVIANCREYNPPDSEYCRCASALEKFF 825
AD++ + NC +YNPPD E A L+ F
Sbjct: 339 ADVRLMFMNCYKYNPPDHEVVTMARMLQDVF 369
>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
Length = 1872
Score = 73.9 bits (180), Expect = 6e-13
Identities = 39/108 (36%), Positives = 63/108 (58%), Gaps = 3/108 (2%)
Query: 727 LKDPDQLYTT--LKNLLAQ-IKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLR 783
L D DQ+ + L N++ Q + + P +WPF PV K PDYY+VI P+DL+T+ + +
Sbjct: 1499 LDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNIS 1558
Query: 784 SRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
Y +R+ F+ D+ ++AN +YN P+S+Y + A + Y L E
Sbjct: 1559 KHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTE 1606
Score = 61.6 bits (148), Expect = 3e-09
Identities = 30/99 (30%), Positives = 54/99 (54%)
Query: 733 LYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKL 792
L + L++++ ++ P+ +PF PV DYY++I P+DL+T+ E +R R Y +R+
Sbjct: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1444
Query: 793 FVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
F L+ ++ N YN P + + ++ KLKE
Sbjct: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE 1483
>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
Length = 1893
Score = 73.9 bits (180), Expect = 6e-13
Identities = 39/108 (36%), Positives = 63/108 (58%), Gaps = 3/108 (2%)
Query: 727 LKDPDQLYTT--LKNLLAQ-IKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLR 783
L D DQ+ + L N++ Q + + P +WPF PV K PDYY+VI P+DL+T+ + +
Sbjct: 1520 LDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNIS 1579
Query: 784 SRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
Y +R+ F+ D+ ++AN +YN P+S+Y + A + Y L E
Sbjct: 1580 KHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCYQTLTE 1627
Score = 61.6 bits (148), Expect = 3e-09
Identities = 30/99 (30%), Positives = 54/99 (54%)
Query: 733 LYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKL 792
L + L++++ ++ P+ +PF PV DYY++I P+DL+T+ E +R R Y +R+
Sbjct: 1406 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1465
Query: 793 FVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
F L+ ++ N YN P + + ++ KLKE
Sbjct: 1466 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE 1504
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 73.9 bits (180), Expect = 6e-13
Identities = 30/100 (30%), Positives = 59/100 (59%)
Query: 735 TTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFV 794
+ + L+ ++ H +WPF++ V K + PDYY++I+ PI L + E++ Y F+
Sbjct: 1404 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1463
Query: 795 ADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGL 834
D++ + +NC EYNP ++ + + L+ FF+ + ++ GL
Sbjct: 1464 DDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGL 1503
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 73.9 bits (180), Expect = 6e-13
Identities = 30/100 (30%), Positives = 59/100 (59%)
Query: 735 TTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFV 794
+ + L+ ++ H +WPF++ V K + PDYY++I+ PI L + E++ Y F+
Sbjct: 1436 SAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFI 1495
Query: 795 ADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGL 834
D++ + +NC EYNP ++ + + L+ FF+ + ++ GL
Sbjct: 1496 DDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHIQAQKLGL 1535
>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
sapiens]
Length = 1826
Score = 73.2 bits (178), Expect = 1e-12
Identities = 37/108 (34%), Positives = 63/108 (58%), Gaps = 3/108 (2%)
Query: 727 LKDPDQLYTT--LKNLLAQ-IKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLR 783
L D DQ+ + L N++ Q + + P +WPF PV K PDYY++I P+DL+T+ + +
Sbjct: 1518 LDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNIS 1577
Query: 784 SRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
Y +R+ F+ D+ ++AN +YN P+S+Y + A + Y + E
Sbjct: 1578 KHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNICYQTITE 1625
Score = 57.0 bits (136), Expect = 7e-08
Identities = 29/99 (29%), Positives = 52/99 (52%)
Query: 733 LYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKL 792
L + L++++ ++ P+ PF PV DYY++I P+DL+T+ E +R Y +R+
Sbjct: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREE 1463
Query: 793 FVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
F L+ ++ N YN P + + ++ KLKE
Sbjct: 1464 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKE 1502
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 72.0 bits (175), Expect = 2e-12
Identities = 39/123 (31%), Positives = 62/123 (50%), Gaps = 1/123 (0%)
Query: 709 PGIRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEV 768
P E G P K + +++ T + +L +++SH +AWPF+EPV Y +
Sbjct: 1775 PRYSEEGLSP-SKRRRLSMRNHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLVSGYRRI 1833
Query: 769 IRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFK 828
I+ P+D TM ERL Y + + F AD V NC+ +N DSE + + +FF +
Sbjct: 1834 IKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMRRFFESR 1893
Query: 829 LKE 831
+E
Sbjct: 1894 WEE 1896
Score = 37.4 bits (85), Expect = 0.058
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 6/62 (9%)
Query: 3 EPSQAPTPAPAAQPRPLQS------PAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAG 56
E + P QP P QS PA +P +P SPA + + +P +P +P PA
Sbjct: 398 ETQSSDFPPSLTQPAPDQSSTIQLHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAA 457
Query: 57 ST 58
ST
Sbjct: 458 ST 459
Score = 35.4 bits (80), Expect = 0.22
Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 4/53 (7%)
Query: 7 APTPAPAAQPRPLQSPAPAPTPTPAPS----PASAPIPTPTPAPAPAPAAAPA 55
AP + Q P SPA +PT +PA S PA++P +P PA + +PA
Sbjct: 412 APDQSSTIQLHPATSPAVSPTTSPAVSLVVSPAASPEISPEVCPAASTVVSPA 464
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 71.2 bits (173), Expect = 4e-12
Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 20/179 (11%)
Query: 668 IKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKEL 727
+ K+K + +K + PG G + +P +R +P+ K K+L
Sbjct: 273 LAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPI-KPPRKDL 331
Query: 728 KDPDQLYTT----------------LKNLLAQIKSHPSAWPFMEPVKKSEAP--DYYEVI 769
D Q + + LK LL++ K AWPF +PV S DY+++I
Sbjct: 332 PDSQQQHQSSKKGKLSEQLKHCNGILKELLSK-KHAAYAWPFYKPVDASALGLHDYHDII 390
Query: 770 RFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFK 828
+ P+DL T+ ++ +R Y + F AD++ + +NC +YNPPD + A L+ F F+
Sbjct: 391 KHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFR 449
Score = 69.3 bits (168), Expect = 1e-11
Identities = 44/141 (31%), Positives = 64/141 (45%), Gaps = 5/141 (3%)
Query: 694 SCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKD---PDQLYTTLKNLLAQIKSHPSA 750
S EG + SVP ++ T P E K +QL K ++ + H A
Sbjct: 37 SLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFA 96
Query: 751 WPFMEPVK--KSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYN 808
WPF +PV K PDY+++I+ P+D+ T+ RL + YY + D + NC YN
Sbjct: 97 WPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
Query: 809 PPDSEYCRCASALEKFFYFKL 829
P + A LEK F K+
Sbjct: 157 KPTDDIVLMAQTLEKIFLQKV 177
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 71.2 bits (173), Expect = 4e-12
Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 20/179 (11%)
Query: 668 IKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLGKEKGKEL 727
+ K+K + +K + PG G + +P +R +P+ K K+L
Sbjct: 273 LAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPI-KPPRKDL 331
Query: 728 KDPDQLYTT----------------LKNLLAQIKSHPSAWPFMEPVKKSEAP--DYYEVI 769
D Q + + LK LL++ K AWPF +PV S DY+++I
Sbjct: 332 PDSQQQHQSSKKGKLSEQLKHCNGILKELLSK-KHAAYAWPFYKPVDASALGLHDYHDII 390
Query: 770 RFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFK 828
+ P+DL T+ ++ +R Y + F AD++ + +NC +YNPPD + A L+ F F+
Sbjct: 391 KHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFR 449
Score = 69.3 bits (168), Expect = 1e-11
Identities = 44/141 (31%), Positives = 64/141 (45%), Gaps = 5/141 (3%)
Query: 694 SCFKEGVRQIPVESVPGIRETGWKPLGKEKGKELKD---PDQLYTTLKNLLAQIKSHPSA 750
S EG + SVP ++ T P E K +QL K ++ + H A
Sbjct: 37 SLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFA 96
Query: 751 WPFMEPVK--KSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYN 808
WPF +PV K PDY+++I+ P+D+ T+ RL + YY + D + NC YN
Sbjct: 97 WPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYN 156
Query: 809 PPDSEYCRCASALEKFFYFKL 829
P + A LEK F K+
Sbjct: 157 KPTDDIVLMAQTLEKIFLQKV 177
>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 70.1 bits (170), Expect = 8e-12
Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 9/102 (8%)
Query: 4 PSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGS------ 57
P+ AP AP A P + APAP P PAP+PA AP+ P PAPAPAPA APA +
Sbjct: 149 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAA 208
Query: 58 ---TGTGGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRG 96
+ G G G D G+S + A A G
Sbjct: 209 PQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANG 250
Score = 69.7 bits (169), Expect = 1e-11
Identities = 40/99 (40%), Positives = 49/99 (49%), Gaps = 4/99 (4%)
Query: 4 PSQAPTPAPAAQP--RPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTG 61
P+ AP PAP A P P+ AP P PAP+PA AP P PAPAPAPA APA +
Sbjct: 145 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 204
Query: 62 GPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRA 100
A G + + G Q+ A Q + + G P A
Sbjct: 205 PDAAPQESAEQGANQGQRG--QEPLADQLHSGISGRPAA 241
Score = 64.7 bits (156), Expect = 3e-10
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 9/91 (9%)
Query: 8 PTPAPAAQPRPLQ--SPAPAPTPTPAPSPASAPI------PTPTPAPAPAPAAAP-AGST 58
P PAPA+ P P+ +PAPAP P P +P +AP+ P P PAPAPAPA AP A
Sbjct: 129 PVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPA 188
Query: 59 GTGGPGVGSGGAGSGGDPARPGLSQQQRASQ 89
P A + A P S +Q A+Q
Sbjct: 189 PAPAPAPAPAPAPAPAPDAAPQESAEQGANQ 219
Score = 30.4 bits (67), Expect = 7.1
Identities = 17/49 (34%), Positives = 20/49 (40%), Gaps = 7/49 (14%)
Query: 7 APTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPA 55
+P PAA+ AP P S P+P P P P P APA
Sbjct: 105 SPPLEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLAPA 146
>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 70.1 bits (170), Expect = 8e-12
Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 9/102 (8%)
Query: 4 PSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGS------ 57
P+ AP AP A P + APAP P PAP+PA AP+ P PAPAPAPA APA +
Sbjct: 149 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAA 208
Query: 58 ---TGTGGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRG 96
+ G G G D G+S + A A G
Sbjct: 209 PQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANG 250
Score = 69.7 bits (169), Expect = 1e-11
Identities = 40/99 (40%), Positives = 49/99 (49%), Gaps = 4/99 (4%)
Query: 4 PSQAPTPAPAAQP--RPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTG 61
P+ AP PAP A P P+ AP P PAP+PA AP P PAPAPAPA APA +
Sbjct: 145 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 204
Query: 62 GPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRA 100
A G + + G Q+ A Q + + G P A
Sbjct: 205 PDAAPQESAEQGANQGQRG--QEPLADQLHSGISGRPAA 241
Score = 64.7 bits (156), Expect = 3e-10
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 9/91 (9%)
Query: 8 PTPAPAAQPRPLQ--SPAPAPTPTPAPSPASAPI------PTPTPAPAPAPAAAP-AGST 58
P PAPA+ P P+ +PAPAP P P +P +AP+ P P PAPAPAPA AP A
Sbjct: 129 PVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPA 188
Query: 59 GTGGPGVGSGGAGSGGDPARPGLSQQQRASQ 89
P A + A P S +Q A+Q
Sbjct: 189 PAPAPAPAPAPAPAPAPDAAPQESAEQGANQ 219
Score = 30.4 bits (67), Expect = 7.1
Identities = 17/49 (34%), Positives = 20/49 (40%), Gaps = 7/49 (14%)
Query: 7 APTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPA 55
+P PAA+ AP P S P+P P P P P APA
Sbjct: 105 SPPLEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLAPA 146
>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
sapiens]
Length = 316
Score = 70.1 bits (170), Expect = 8e-12
Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 9/102 (8%)
Query: 4 PSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGS------ 57
P+ AP AP A P + APAP P PAP+PA AP+ P PAPAPAPA APA +
Sbjct: 160 PAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAA 219
Query: 58 ---TGTGGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRG 96
+ G G G D G+S + A A G
Sbjct: 220 PQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANG 261
Score = 69.7 bits (169), Expect = 1e-11
Identities = 40/99 (40%), Positives = 49/99 (49%), Gaps = 4/99 (4%)
Query: 4 PSQAPTPAPAAQP--RPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTG 61
P+ AP PAP A P P+ AP P PAP+PA AP P PAPAPAPA APA +
Sbjct: 156 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215
Query: 62 GPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRA 100
A G + + G Q+ A Q + + G P A
Sbjct: 216 PDAAPQESAEQGANQGQRG--QEPLADQLHSGISGRPAA 252
Score = 64.7 bits (156), Expect = 3e-10
Identities = 38/91 (41%), Positives = 47/91 (51%), Gaps = 9/91 (9%)
Query: 8 PTPAPAAQPRPLQ--SPAPAPTPTPAPSPASAPI------PTPTPAPAPAPAAAP-AGST 58
P PAPA+ P P+ +PAPAP P P +P +AP+ P P PAPAPAPA AP A
Sbjct: 140 PVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPA 199
Query: 59 GTGGPGVGSGGAGSGGDPARPGLSQQQRASQ 89
P A + A P S +Q A+Q
Sbjct: 200 PAPAPAPAPAPAPAPAPDAAPQESAEQGANQ 230
Score = 30.4 bits (67), Expect = 7.1
Identities = 17/49 (34%), Positives = 20/49 (40%), Gaps = 7/49 (14%)
Query: 7 APTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPA 55
+P PAA+ AP P S P+P P P P P APA
Sbjct: 116 SPPLEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLAPA 157
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 67.8 bits (164), Expect = 4e-11
Identities = 32/101 (31%), Positives = 52/101 (51%)
Query: 725 KELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRS 784
K +D + +L ++++H AWPF+ PV P Y +VI+ P+D T+ E+L S
Sbjct: 2057 KPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSS 2116
Query: 785 RYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFF 825
Y + F D++ V NC +N DS+ R + K+F
Sbjct: 2117 GQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYF 2157
Score = 30.4 bits (67), Expect = 7.1
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 AEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTG 61
A+ S A P +QP P+ +P+PTPAP +SA P A +P G + G
Sbjct: 1576 ADMSTASLVTPQSQP-----PSKSPSPTPAPLGSSAQNPVGLNPFALSPLQVKGGVSMMG 1630
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 66.2 bits (160), Expect = 1e-10
Identities = 32/87 (36%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
Query: 747 HPSAWPFMEPVK--KSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANC 804
H AWPF +PV K PDY+++I+ P+D+ T+ +RL + YY + + D + NC
Sbjct: 53 HQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNC 112
Query: 805 REYNPPDSEYCRCASALEKFFYFKLKE 831
YN P + A ALEK F K+ +
Sbjct: 113 YIYNKPTDDIVLMAQALEKIFLQKVAQ 139
Score = 65.9 bits (159), Expect = 2e-10
Identities = 36/106 (33%), Positives = 59/106 (55%), Gaps = 3/106 (2%)
Query: 722 EKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKS--EAPDYYEVIRFPIDLKTMT 779
+KGK + + L+ +L++ K AWPF +PV E DY+++I+ P+DL T+
Sbjct: 304 KKGKLSEHLRYCDSILREMLSK-KHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVK 362
Query: 780 ERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFF 825
++ R Y + F AD++ + +NC +YNPPD E A L+ F
Sbjct: 363 RKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVF 408
Score = 34.3 bits (77), Expect = 0.49
Identities = 18/46 (39%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Query: 9 TPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAP 54
TP + P Q+P A TP P + +P P PA AP P A P
Sbjct: 181 TPFQSVPPTVSQTPVIAATPVPTITANVTSVPVP-PAAAPPPPATP 225
Score = 30.4 bits (67), Expect = 7.1
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 3/51 (5%)
Query: 4 PSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAP 54
P+ + TP AA P P + P P PA+AP P TP P P
Sbjct: 188 PTVSQTPVIAATPVPTITANVTSVPVP---PAAAPPPPATPIVPVVPPTPP 235
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 65.5 bits (158), Expect = 2e-10
Identities = 36/95 (37%), Positives = 53/95 (55%), Gaps = 3/95 (3%)
Query: 738 KNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRY--YVTRKLFVA 795
+ LL + H + F +PV + PDYY++I+ P+DL T+ +RL+ Y Y + FVA
Sbjct: 909 ERLLLFLYCHEMSLAFQDPVPLT-VPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVA 967
Query: 796 DLQRVIANCREYNPPDSEYCRCASALEKFFYFKLK 830
D + + NC E+N PDSE LE +F LK
Sbjct: 968 DFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLK 1002
Score = 30.0 bits (66), Expect = 9.3
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 15 QPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAP--APAAAPAGSTGTGGPGVGSGGAGS 72
QPRP + + PSP A T T P +P+A+ GS G+ G GA S
Sbjct: 649 QPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADS 708
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 65.5 bits (158), Expect = 2e-10
Identities = 36/95 (37%), Positives = 53/95 (55%), Gaps = 3/95 (3%)
Query: 738 KNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRY--YVTRKLFVA 795
+ LL + H + F +PV + PDYY++I+ P+DL T+ +RL+ Y Y + FVA
Sbjct: 875 ERLLLFLYCHEMSLAFQDPVPLT-VPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVA 933
Query: 796 DLQRVIANCREYNPPDSEYCRCASALEKFFYFKLK 830
D + + NC E+N PDSE LE +F LK
Sbjct: 934 DFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLK 968
Score = 30.0 bits (66), Expect = 9.3
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 15 QPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAP--APAAAPAGSTGTGGPGVGSGGAGS 72
QPRP + + PSP A T T P +P+A+ GS G+ G GA S
Sbjct: 615 QPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADS 674
>gi|4503519 eukaryotic translation initiation factor 3, subunit 5
epsilon, 47kDa [Homo sapiens]
Length = 357
Score = 62.0 bits (149), Expect = 2e-09
Identities = 32/80 (40%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 1 MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT 60
MA P+ P AP A P P+ + APA P P P+PA+AP+P PA + PAAA A +
Sbjct: 1 MATPA-VPVSAPPATPTPVPAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAP 59
Query: 61 GGPGVGSGGAGSGGDPARPG 80
G + PA PG
Sbjct: 60 GQTPASAQAPAQTPAPALPG 79
Score = 53.1 bits (126), Expect = 1e-06
Identities = 28/75 (37%), Positives = 33/75 (44%)
Query: 4 PSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGP 63
P+ AP PA P P +P PA P + PA+A T P PA A APA + P
Sbjct: 19 PAAAPASVPAPTPAPAAAPVPAAAPASSSDPAAAAAATAAPGQTPASAQAPAQTPAPALP 78
Query: 64 GVGSGGAGSGGDPAR 78
G G GG R
Sbjct: 79 GPALPGPFPGGRVVR 93
Score = 46.6 bits (109), Expect = 1e-04
Identities = 30/76 (39%), Positives = 37/76 (48%), Gaps = 11/76 (14%)
Query: 18 PLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPA 77
P+ +P PTP PA +PAS P PTP APAAAP + P S A + A
Sbjct: 7 PVSAPPATPTPVPAAAPASVPAPTP------APAAAPVPA---AAPASSSDPAAAAAATA 57
Query: 78 RPGLSQQQRASQRKAQ 93
PG Q ++Q AQ
Sbjct: 58 APG--QTPASAQAPAQ 71
>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
sapiens]
Length = 1110
Score = 61.2 bits (147), Expect = 4e-09
Identities = 34/97 (35%), Positives = 55/97 (56%), Gaps = 4/97 (4%)
Query: 738 KNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLR---SRYYVTRKLFV 794
+ LL + H + F EPV S P+YY++I+ P+DL T+ ++L+ S++Y FV
Sbjct: 967 ERLLLYLYCHELSIEFQEPVPAS-IPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFV 1025
Query: 795 ADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
AD++ + NC +N DSE + A+ +F KL E
Sbjct: 1026 ADVRLIFKNCERFNEADSEVAQAGKAVALYFEDKLTE 1062
Score = 37.4 bits (85), Expect = 0.058
Identities = 15/25 (60%), Positives = 18/25 (72%)
Query: 29 TPAPSPASAPIPTPTPAPAPAPAAA 53
TPAP+PASAP P P+ P P P A+
Sbjct: 96 TPAPAPASAPAPGPSAGPPPGPPAS 120
Score = 33.1 bits (74), Expect = 1.1
Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 9/76 (11%)
Query: 23 APAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGTGGPGVGSGGAGSGGDPARPGLS 82
A +P + A + TP PAPA APA P+ G P S D +
Sbjct: 78 ASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPP-------ASLLDTC--AVC 128
Query: 83 QQQRASQRKAQVRGLP 98
QQ S+R+A+ + LP
Sbjct: 129 QQSLQSRREAEPKLLP 144
Score = 32.7 bits (73), Expect = 1.4
Identities = 16/44 (36%), Positives = 20/44 (45%)
Query: 11 APAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAP 54
A + + SPA + A S P P P APAP P+A P
Sbjct: 70 ASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGP 113
Score = 32.7 bits (73), Expect = 1.4
Identities = 12/24 (50%), Positives = 16/24 (66%)
Query: 19 LQSPAPAPTPTPAPSPASAPIPTP 42
+ +PAPAP PAP P++ P P P
Sbjct: 94 VSTPAPAPASAPAPGPSAGPPPGP 117
Score = 30.0 bits (66), Expect = 9.3
Identities = 14/33 (42%), Positives = 19/33 (57%), Gaps = 4/33 (12%)
Query: 9 TPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPT 41
TPAPA P +PAP P+ P P P ++ + T
Sbjct: 96 TPAPA----PASAPAPGPSAGPPPGPPASLLDT 124
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
sapiens]
Length = 1205
Score = 60.5 bits (145), Expect = 6e-09
Identities = 32/85 (37%), Positives = 43/85 (50%)
Query: 737 LKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVAD 796
L+ L ++ A F EPV SE PDY E I P+D TM +L S Y T + F D
Sbjct: 598 LRTTLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEED 657
Query: 797 LQRVIANCREYNPPDSEYCRCASAL 821
++ NC +YN D+ + R A L
Sbjct: 658 FNLIVTNCMKYNAKDTIFHRAAVRL 682
>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
Length = 1602
Score = 59.3 bits (142), Expect = 1e-08
Identities = 27/79 (34%), Positives = 46/79 (58%)
Query: 753 FMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDS 812
F + K + PDYY +I+ PIDLKT+ +R+++ Y + D+ + N + YN P S
Sbjct: 208 FQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGS 267
Query: 813 EYCRCASALEKFFYFKLKE 831
+ + A++++K FY K E
Sbjct: 268 QVFKDANSIKKIFYMKKAE 286
Score = 58.5 bits (140), Expect = 2e-08
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 14/196 (7%)
Query: 643 KDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQ 702
++YE +EC+LN + + I K++++ +Q K KE R+
Sbjct: 408 QEYETLDHLECDLN--LMFENAKRYNVPNSAIYKRVLKLQQVMQAKK-------KELARR 458
Query: 703 IPVESVPGIRETGWKPLGKEKGKELKD-PDQLYTTLKNLLAQIKSHPSAWP----FMEPV 757
+E + + G K K K+ Q L N++ + + S FM
Sbjct: 459 DDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKP 518
Query: 758 KKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRC 817
K + PDYY++I P+DLK + +R+ Y + + D++ + N R YN S+
Sbjct: 519 SKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYND 578
Query: 818 ASALEKFFYFKLKEGG 833
A LEK K KE G
Sbjct: 579 AHILEKLLKEKRKELG 594
Score = 50.4 bits (119), Expect = 7e-06
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Query: 732 QLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRK 791
QLY T+++ + A PF K + PDYY+ I+ PI L+ + +L+++ Y T
Sbjct: 356 QLYDTVRSCRNN-QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLD 414
Query: 792 LFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
DL + N + YN P+S + L++ K KE
Sbjct: 415 HLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKE 454
Score = 50.1 bits (118), Expect = 9e-06
Identities = 25/69 (36%), Positives = 35/69 (50%)
Query: 753 FMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDS 812
F+ K+ PDYYEV+ PIDL + ++L+ Y L AD Q + N + Y PDS
Sbjct: 72 FIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDS 131
Query: 813 EYCRCASAL 821
+ A L
Sbjct: 132 PEYKAACKL 140
Score = 40.4 bits (93), Expect = 0.007
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 731 DQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTR 790
+++Y +KN + SA F+ +SE PDYY I+ P+D++ + + + Y
Sbjct: 631 NEVYEAVKNYTDKRGRRLSAI-FLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDI 689
Query: 791 KLFVADLQRVIANCREYNPPDSEYCRCASALEK 823
V D + N YN P+S + A L K
Sbjct: 690 DSMVEDFVMMFNNACTYNEPESLIYKDALVLHK 722
>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
Length = 1582
Score = 59.3 bits (142), Expect = 1e-08
Identities = 27/79 (34%), Positives = 46/79 (58%)
Query: 753 FMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDS 812
F + K + PDYY +I+ PIDLKT+ +R+++ Y + D+ + N + YN P S
Sbjct: 208 FQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGS 267
Query: 813 EYCRCASALEKFFYFKLKE 831
+ + A++++K FY K E
Sbjct: 268 QVFKDANSIKKIFYMKKAE 286
Score = 58.5 bits (140), Expect = 2e-08
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 14/196 (7%)
Query: 643 KDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQ 702
++YE +EC+LN + + I K++++ +Q K KE R+
Sbjct: 440 QEYETLDHLECDLN--LMFENAKRYNVPNSAIYKRVLKLQQVMQAKK-------KELARR 490
Query: 703 IPVESVPGIRETGWKPLGKEKGKELKD-PDQLYTTLKNLLAQIKSHPSAWP----FMEPV 757
+E + + G K K K+ Q L N++ + + S FM
Sbjct: 491 DDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKP 550
Query: 758 KKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRC 817
K + PDYY++I P+DLK + +R+ Y + + D++ + N R YN S+
Sbjct: 551 SKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYND 610
Query: 818 ASALEKFFYFKLKEGG 833
A LEK K KE G
Sbjct: 611 AHILEKLLKEKRKELG 626
Score = 50.4 bits (119), Expect = 7e-06
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Query: 732 QLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRK 791
QLY T+++ + A PF K + PDYY+ I+ PI L+ + +L+++ Y T
Sbjct: 388 QLYDTVRSCRNN-QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLD 446
Query: 792 LFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
DL + N + YN P+S + L++ K KE
Sbjct: 447 HLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKE 486
Score = 50.1 bits (118), Expect = 9e-06
Identities = 25/69 (36%), Positives = 35/69 (50%)
Query: 753 FMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDS 812
F+ K+ PDYYEV+ PIDL + ++L+ Y L AD Q + N + Y PDS
Sbjct: 72 FIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDS 131
Query: 813 EYCRCASAL 821
+ A L
Sbjct: 132 PEYKAACKL 140
Score = 40.4 bits (93), Expect = 0.007
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 731 DQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTR 790
+++Y +KN + SA F+ +SE PDYY I+ P+D++ + + + Y
Sbjct: 663 NEVYEAVKNYTDKRGRRLSAI-FLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDI 721
Query: 791 KLFVADLQRVIANCREYNPPDSEYCRCASALEK 823
V D + N YN P+S + A L K
Sbjct: 722 DSMVEDFVMMFNNACTYNEPESLIYKDALVLHK 754
>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
Length = 1582
Score = 59.3 bits (142), Expect = 1e-08
Identities = 27/79 (34%), Positives = 46/79 (58%)
Query: 753 FMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDS 812
F + K + PDYY +I+ PIDLKT+ +R+++ Y + D+ + N + YN P S
Sbjct: 208 FQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGS 267
Query: 813 EYCRCASALEKFFYFKLKE 831
+ + A++++K FY K E
Sbjct: 268 QVFKDANSIKKIFYMKKAE 286
Score = 58.5 bits (140), Expect = 2e-08
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 14/196 (7%)
Query: 643 KDYEGATLMECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQ 702
++YE +EC+LN + + I K++++ +Q K KE R+
Sbjct: 440 QEYETLDHLECDLN--LMFENAKRYNVPNSAIYKRVLKLQQVMQAKK-------KELARR 490
Query: 703 IPVESVPGIRETGWKPLGKEKGKELKD-PDQLYTTLKNLLAQIKSHPSAWP----FMEPV 757
+E + + G K K K+ Q L N++ + + S FM
Sbjct: 491 DDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKP 550
Query: 758 KKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRC 817
K + PDYY++I P+DLK + +R+ Y + + D++ + N R YN S+
Sbjct: 551 SKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYND 610
Query: 818 ASALEKFFYFKLKEGG 833
A LEK K KE G
Sbjct: 611 AHILEKLLKEKRKELG 626
Score = 50.4 bits (119), Expect = 7e-06
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Query: 732 QLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRK 791
QLY T+++ + A PF K + PDYY+ I+ PI L+ + +L+++ Y T
Sbjct: 388 QLYDTVRSCRNN-QGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLD 446
Query: 792 LFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKE 831
DL + N + YN P+S + L++ K KE
Sbjct: 447 HLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKE 486
Score = 50.1 bits (118), Expect = 9e-06
Identities = 25/69 (36%), Positives = 35/69 (50%)
Query: 753 FMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDS 812
F+ K+ PDYYEV+ PIDL + ++L+ Y L AD Q + N + Y PDS
Sbjct: 72 FIRAPKRRNQPDYYEVVSQPIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDS 131
Query: 813 EYCRCASAL 821
+ A L
Sbjct: 132 PEYKAACKL 140
Score = 40.4 bits (93), Expect = 0.007
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 731 DQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTERLRSRYYVTR 790
+++Y +KN + SA F+ +SE PDYY I+ P+D++ + + + Y
Sbjct: 663 NEVYEAVKNYTDKRGRRLSAI-FLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDI 721
Query: 791 KLFVADLQRVIANCREYNPPDSEYCRCASALEK 823
V D + N YN P+S + A L K
Sbjct: 722 DSMVEDFVMMFNNACTYNEPESLIYKDALVLHK 754
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,679,804
Number of Sequences: 37866
Number of extensions: 2285147
Number of successful extensions: 71775
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1105
Number of HSP's successfully gapped in prelim test: 1145
Number of HSP's that attempted gapping in prelim test: 25040
Number of HSP's gapped (non-prelim): 25743
length of query: 837
length of database: 18,247,518
effective HSP length: 111
effective length of query: 726
effective length of database: 14,044,392
effective search space: 10196228592
effective search space used: 10196228592
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.