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Search of human proteins with 153791377
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153791377 apoptosis-inducing protein D [Homo sapiens]
(279 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153791377 apoptosis-inducing protein D [Homo sapiens] 573 e-164
gi|13375827 phafin 2 [Homo sapiens] 294 7e-80
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens] 129 4e-30
gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens] 94 2e-19
gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens] 83 3e-16
gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens] 81 9e-16
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens] 78 1e-14
gi|24797153 faciogenital dysplasia protein [Homo sapiens] 71 1e-12
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 68 8e-12
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 67 1e-11
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 67 2e-11
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 66 3e-11
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 66 3e-11
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 65 5e-11
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 64 1e-10
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 61 9e-10
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 61 9e-10
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 61 1e-09
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 60 2e-09
gi|217272865 myotubularin related protein 4 [Homo sapiens] 59 4e-09
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 59 4e-09
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 59 4e-09
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 59 4e-09
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 59 5e-09
gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 58 1e-08
gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 58 1e-08
gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform... 57 2e-08
gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo sa... 57 2e-08
gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform... 54 1e-07
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 54 1e-07
>gi|153791377 apoptosis-inducing protein D [Homo sapiens]
Length = 279
Score = 573 bits (1478), Expect = e-164
Identities = 279/279 (100%), Positives = 279/279 (100%)
Query: 1 MVDHLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFND 60
MVDHLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFND
Sbjct: 1 MVDHLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFND 60
Query: 61 ILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQ 120
ILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQ
Sbjct: 61 ILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQ 120
Query: 121 EWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGF 180
EWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGF
Sbjct: 121 EWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGF 180
Query: 181 VVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICG 240
VVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICG
Sbjct: 181 VVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICG 240
Query: 241 ASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS 279
ASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS
Sbjct: 241 ASSGDDDDSDEDKEGSRDGDWPSSVEFYASGVAWSAFHS 279
>gi|13375827 phafin 2 [Homo sapiens]
Length = 249
Score = 294 bits (752), Expect = 7e-80
Identities = 141/252 (55%), Positives = 176/252 (69%), Gaps = 3/252 (1%)
Query: 1 MVDHLANTEINSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFND 60
MVD LAN+E N++RI+ VE+CFGA+GQPL +PGRVL+GEGVLTK CRKK K R FFLFND
Sbjct: 1 MVDRLANSEANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFND 60
Query: 61 ILVYGSIVLNKRKYRSQHIIPLEEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQ 120
ILVYG+IV+ K+KY QHIIPLE VT++ + + +N W+IKT KSF V AA+ATE+
Sbjct: 61 ILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKS 120
Query: 121 EWISHIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGF 180
EW++HI +CV L +G+ PS EHAA W+PD +CMRC + +F+ + RRHHCRKCGF
Sbjct: 121 EWMNHINKCVTDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGF 180
Query: 181 VVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICG 240
VVC CS +RFLLP S KPVR+C CY L+A + A Q A S L P+
Sbjct: 181 VVCGPCSEKRFLLPSQSSKPVRICDFCYDLLSA---GDMATCQPARSDSYSQSLKSPLND 237
Query: 241 ASSGDDDDSDED 252
S DDDD D
Sbjct: 238 MSDDDDDDDSSD 249
>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
Length = 1430
Score = 129 bits (323), Expect = 4e-30
Identities = 79/216 (36%), Positives = 112/216 (51%), Gaps = 24/216 (11%)
Query: 32 PGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLNKRKYRSQHIIPLEEVTLELLP 91
PGRV L EG+L K RK +PR+FFLFND L+Y + V Y+ +++ L + + P
Sbjct: 1086 PGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPV-QSGMYKLNNMLSLAGMKVRK-P 1143
Query: 92 ETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVRR--QLRATGRP--------- 140
+N I++ ++SF++SA+SATER EW+ I + + R T P
Sbjct: 1144 TQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEEYAKKRITFCPSRSLDEADS 1203
Query: 141 -------PSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLL 193
P A WIPD +CM CT + F+ RRHHCR CG +VC CS ++ L
Sbjct: 1204 ENKEEVSPLGSKAPIWIPDTRATMCMICT-SEFTLTWRRHHCRACGKIVCQACSSNKYGL 1262
Query: 194 PRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPG 229
L +P RVC C++EL Q+ + GSPG
Sbjct: 1263 DYLKNQPARVCEHCFQEL---QKLDHQHSPRIGSPG 1295
>gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]
Length = 1462
Score = 93.6 bits (231), Expect = 2e-19
Identities = 67/231 (29%), Positives = 101/231 (43%), Gaps = 40/231 (17%)
Query: 11 NSQRIAAVESCFGASGQPLALPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLN 70
N Q++ +E G L PGR L EG L K K +PR FL ND+L+Y +
Sbjct: 1090 NLQKLVHIEHSVRGQGD-LLQPGREFLKEGTLMKVTGKNRRPRHLFLMNDVLLY-TYPQK 1147
Query: 71 KRKYRSQHIIPLEEV-----TLELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISH 125
KYR ++ + + + +E +P L+ I+T++ ++SA+S ER EW
Sbjct: 1148 DGKYRLKNTLAVANMKVSRPVMEKVPYALK------IETSESCLMLSASSCAERDEWYGC 1201
Query: 126 IEECVRRQLRATG--------------------RPPSTEHAAPWIPDKATDICMRCTQTR 165
+ + +A RPP+ +P +CM C
Sbjct: 1202 LSRALPEDYKAQALAAFHHSVEIRERLGVSLGERPPTL------VPVTHVMMCMNCG-CD 1254
Query: 166 FSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQR 216
FS RRHHC CG +VC CSR ++ L L + +VC C+ EL + R
Sbjct: 1255 FSLTLRRHHCHACGKIVCRNCSRNKYPLKYLKDRMAKVCDGCFGELKKRGR 1305
>gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens]
Length = 766
Score = 82.8 bits (203), Expect = 3e-16
Identities = 66/220 (30%), Positives = 104/220 (47%), Gaps = 34/220 (15%)
Query: 32 PGRVLLGEGVLTKECRKK--AKPRIFFLFNDILVYG----SIVLNKRKYRSQHIIP---L 82
P L+ EG + K + A+ R FLFN++L+Y S+V +K R++ I +
Sbjct: 419 PSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKI 478
Query: 83 EEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVR--RQLRATGRP 140
E E P T Q + +++ + A+SA +++EWI ++E + Q T R
Sbjct: 479 VETQNEEYPHTFQVSGK------ERTLELQASSAQDKEEWIKALQETIDAFHQRHETFRN 532
Query: 141 PSTE---------------HAAPWIPDKATDICMRCTQTRFSALTRR-HHCRKCGFVVCA 184
+ A WI D +CM+C + F+ALTRR HHCR CG+VVC
Sbjct: 533 AIAKDNDIHSEVSTAELGKRAPRWIRDNEVTMCMKCKEP-FNALTRRRHHCRACGYVVCW 591
Query: 185 ECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQG 224
+CS + L K +VC CY+ ++ EE + +G
Sbjct: 592 KCSDYKAQLEYDGGKLSKVCKDCYQIISGFTDSEEKKRKG 631
>gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens]
Length = 655
Score = 81.3 bits (199), Expect = 9e-16
Identities = 61/219 (27%), Positives = 99/219 (45%), Gaps = 26/219 (11%)
Query: 32 PGRVLLGEGVLTKECRKKAKP--RIFFLFNDILVY--GSIVLNKRKYRSQHIIPLEEVTL 87
P LL EG + K ++ P R FLFN++L+Y ++ +++ + I + + +
Sbjct: 316 PSNTLLREGPVLKISFRRNDPMERYLFLFNNMLLYCVPRVIQVGAQFQVRTRIDVAGMKV 375
Query: 88 ELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECV------RRQLRATGRPP 141
L + + + +++ +++ + A S E W+ + + +A + P
Sbjct: 376 RELMDA-EFPHSFLVSGKQRTLELQARSQEEMISWMQAFQAAIDQIEKRNETFKAAAQGP 434
Query: 142 STE-------------HAAPWIPDKATDICMRCTQTRFSALTRR-HHCRKCGFVVCAECS 187
+ A W+ DK +CMRC Q F+ALTRR HHCR CG+VVCA CS
Sbjct: 435 EGDIQEQELQSEELGLRAPQWVRDKMVTMCMRC-QEPFNALTRRRHHCRACGYVVCARCS 493
Query: 188 RQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAG 226
R L +P RVC CY L E E++ G
Sbjct: 494 DYRAELKYDDNRPNRVCLHCYAFLTGNVLPEAKEDKRRG 532
>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
Length = 2539
Score = 77.8 bits (190), Expect = 1e-14
Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 6/156 (3%)
Query: 71 KRKYRSQHIIPLEEVTLELL-PETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEEC 129
+R+ RS +I L+E+ + PETL A + S S + R+ +
Sbjct: 1735 QREKRSDSVIHLQEIVHQAADPETLPRSPSAEFSPAAPPGISSIHSPSLRERSFPPTQPS 1794
Query: 130 VRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQ 189
AT PP+ W+PD+ ICM C + F+ RRHHCR+CG +VC+ CS +
Sbjct: 1795 QEFVPPAT--PPARHQ---WVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTK 1849
Query: 190 RFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGA 225
+ ++ P RVC CY +E +E+ A
Sbjct: 1850 KMVVEGCRENPARVCDQCYSYCNKDVPEEPSEKPEA 1885
>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
Length = 961
Score = 70.9 bits (172), Expect = 1e-12
Identities = 55/206 (26%), Positives = 95/206 (46%), Gaps = 25/206 (12%)
Query: 27 QPLALPGRVLLGEGVLTKECRKKA--KPRIFFLFNDILVY--GSIVLNKRKYRSQHIIPL 82
+ + P + L+ EG + K K + R LFND L+Y + L +K+ + I +
Sbjct: 582 EDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYCVPRLRLLGQKFSVRARIDV 641
Query: 83 EEVTLELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVRRQ--------- 133
+ + L+ L +++ ++S + A + E+++W+ I + +
Sbjct: 642 DGMELKE-SSNLNLPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTLETFKL 700
Query: 134 LRATGR-----PPST------EHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVV 182
L +T R PP++ + A I +K +CMRC + S RRHHC+ CG VV
Sbjct: 701 LNSTNREDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVV 760
Query: 183 CAECSRQRFLLPRLSPKPVRVCSLCY 208
C +CS R L + + RVC+ CY
Sbjct: 761 CGKCSEFRARLVYDNNRSNRVCTDCY 786
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 68.2 bits (165), Expect = 8e-12
Identities = 32/77 (41%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Query: 133 QLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFL 192
+L A R E W+PD+A C C + F+ + R+HHCR CG + C+ CS
Sbjct: 798 ELAAKTRDGDFEDPPEWVPDEACGFCTAC-KAPFTVIRRKHHCRSCGKIFCSRCSSHSAP 856
Query: 193 LPRLSP-KPVRVCSLCY 208
LPR KPVRVC+ CY
Sbjct: 857 LPRYGQVKPVRVCTHCY 873
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 67.4 bits (163), Expect = 1e-11
Identities = 37/99 (37%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Query: 133 QLRATGRPPST---EHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQ 189
Q + R P T E A W+PD CM+C + RF+ RRHHCR CG V CA C
Sbjct: 677 QFGISARKPFTTLGEVAPVWVPDSQAPNCMKC-EARFTFTKRRHHCRACGKVFCASCCSL 735
Query: 190 RFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSP 228
+ L + K RVC +C+ L Q E + SP
Sbjct: 736 KCKLLYMDRKEARVCVICHSVLMNAQAWENMMSASSQSP 774
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 67.0 bits (162), Expect = 2e-11
Identities = 31/63 (49%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
Query: 149 WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCY 208
W D CM C + FS RRHHCR+CG + CAECS + L P S KPVRVC C+
Sbjct: 1349 WAEDNEVQNCMACGKG-FSVTVRRHHCRQCGNIFCAECSAKNALTPS-SKKPVRVCDACF 1406
Query: 209 REL 211
+L
Sbjct: 1407 NDL 1409
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 66.2 bits (160), Expect = 3e-11
Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 141 PSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLS-PK 199
P A W+ D+ D C C+ RFS RRHHCR CG + C +CSR + + RL
Sbjct: 198 PGRSAADHWVKDEGGDSCSGCS-VRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISS 256
Query: 200 PVRVCSLCYRELAAQQRQEE 219
PVRVC CY L ++ E+
Sbjct: 257 PVRVCQNCYYNLQHERGSED 276
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 66.2 bits (160), Expect = 3e-11
Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 141 PSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLS-PK 199
P A W+ D+ D C C+ RFS RRHHCR CG + C +CSR + + RL
Sbjct: 3443 PGRSAADHWVKDEGGDSCSGCS-VRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISS 3501
Query: 200 PVRVCSLCYRELAAQQRQEE 219
PVRVC CY L ++ E+
Sbjct: 3502 PVRVCQNCYYNLQHERGSED 3521
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 65.5 bits (158), Expect = 5e-11
Identities = 36/91 (39%), Positives = 47/91 (51%), Gaps = 6/91 (6%)
Query: 133 QLRATGRPPST---EHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQ 189
Q + R P T E A W+PD CM+C + RF+ RRHHCR CG V CA C
Sbjct: 677 QFGISARKPFTTLGEVAPVWVPDSQAPNCMKC-EARFTFTKRRHHCRACGKVFCASCCSL 735
Query: 190 RFLLPRLSPKPVRVCSLCYREL--AAQQRQE 218
+ L + K RVC +C+ L AQ R++
Sbjct: 736 KCKLLYMDRKEARVCVICHSVLMNVAQPREQ 766
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 63.9 bits (154), Expect = 1e-10
Identities = 33/82 (40%), Positives = 42/82 (51%), Gaps = 4/82 (4%)
Query: 133 QLRATGRPPST---EHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQ 189
Q + R P T E A W+PD CM+C + RF+ RRHHCR CG V CA C
Sbjct: 677 QFGISARKPFTTLGEVAPVWVPDSQAPNCMKC-EARFTFTKRRHHCRACGKVFCASCCSL 735
Query: 190 RFLLPRLSPKPVRVCSLCYREL 211
+ L + K RVC +C+ L
Sbjct: 736 KCKLLYMDRKEARVCVICHSVL 757
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 61.2 bits (147), Expect = 9e-10
Identities = 29/70 (41%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 149 WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCY 208
W+PD CM C Q +F+ RRHHCR CG V C C ++ L L K RVC +CY
Sbjct: 744 WVPDSEAPNCMNC-QVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE-KEARVCVVCY 801
Query: 209 RELAAQQRQE 218
++ Q E
Sbjct: 802 ETISKAQAFE 811
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 61.2 bits (147), Expect = 9e-10
Identities = 29/70 (41%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 149 WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCY 208
W+PD CM C Q +F+ RRHHCR CG V C C ++ L L K RVC +CY
Sbjct: 744 WVPDSEAPNCMNC-QVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE-KEARVCVVCY 801
Query: 209 RELAAQQRQE 218
++ Q E
Sbjct: 802 ETISKAQAFE 811
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 60.8 bits (146), Expect = 1e-09
Identities = 32/74 (43%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 135 RATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLP 194
RA G P E W+PDK CM+C +F LTR+HHCR+CG C C Q+ L
Sbjct: 28 RAFGSPFGLEEPQ-WVPDKECRRCMQC-DAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLR 85
Query: 195 RLS-PKPVRVCSLC 207
R+ PVR C+ C
Sbjct: 86 RMCFVDPVRQCAEC 99
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 60.5 bits (145), Expect = 2e-09
Identities = 28/60 (46%), Positives = 33/60 (55%), Gaps = 2/60 (3%)
Query: 149 WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCY 208
W+ DK C C + FS R+HHCR CG + C CS LP SPKPVRVC C+
Sbjct: 572 WLKDKEATHCKLC-EKEFSLSKRKHHCRNCGEIFCNACSDNELPLPS-SPKPVRVCDSCH 629
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 59.3 bits (142), Expect = 4e-09
Identities = 38/120 (31%), Positives = 50/120 (41%), Gaps = 13/120 (10%)
Query: 125 HIEECVRRQLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCA 184
H E+C+ TE W+PD C C F RRHHCR CG V CA
Sbjct: 1088 HSEDCLSEASWEPVDKKETE-VTRWVPDHMASHCYNC-DCEFWLAKRRHHCRNCGNVFCA 1145
Query: 185 ECSRQRFLLP-RLSPKPVRVCSLCYRELAAQQRQEEAEEQGAGSPGQPAHLARPICGASS 243
C + +P + PV VC+ CY + + +E +Q L +PI ASS
Sbjct: 1146 GCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQQ----------LKKPIATASS 1195
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 59.3 bits (142), Expect = 4e-09
Identities = 26/60 (43%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 149 WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCY 208
W+ D C +C + FS R+HHCR CG + C CS LP PKPVRVC C+
Sbjct: 531 WLKDDEATHCRQC-EKEFSISRRKHHCRNCGHIFCNTCSSNELALPSY-PKPVRVCDSCH 588
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 59.3 bits (142), Expect = 4e-09
Identities = 26/60 (43%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 149 WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCY 208
W+ D C +C + FS R+HHCR CG + C CS LP PKPVRVC C+
Sbjct: 531 WLKDDEATHCRQC-EKEFSISRRKHHCRNCGHIFCNTCSSNELALPSY-PKPVRVCDSCH 588
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 59.3 bits (142), Expect = 4e-09
Identities = 26/60 (43%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 149 WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCY 208
W+ D C +C + FS R+HHCR CG + C CS LP PKPVRVC C+
Sbjct: 639 WLKDDEATHCRQC-EKEFSISRRKHHCRNCGHIFCNTCSSNELALPSY-PKPVRVCDSCH 696
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 58.9 bits (141), Expect = 5e-09
Identities = 27/71 (38%), Positives = 40/71 (56%), Gaps = 5/71 (7%)
Query: 142 STEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLS-PKP 200
+ E A W+ + C RC + +F +TR+HHCR CG + C +CS + +P+ K
Sbjct: 153 AAERAPDWVD---AEECHRC-RVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKE 208
Query: 201 VRVCSLCYREL 211
VRVC CY +L
Sbjct: 209 VRVCEPCYEQL 219
>gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 57.8 bits (138), Expect = 1e-08
Identities = 61/260 (23%), Positives = 105/260 (40%), Gaps = 54/260 (20%)
Query: 32 PGRVLLGEGVLTKECRKKAKP--RIFFLFNDILVY--GSIVLNKRKYRSQHIIPLEEVTL 87
P L+ EG + K K P R FLFN +++Y + L +K+ + + + + +
Sbjct: 367 PANELIKEGQIQKLSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDISGLQV 426
Query: 88 ELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVRRQ------LRATGRPP 141
+ + + A + ++I K+S + + E++EWI I+ + + +A G
Sbjct: 427 QDIVKPNTA-HTFIITGRKRSLELQTRTEEEKKEWIQIIQATIEKHKQNSETFKAFGGAF 485
Query: 142 STEH---AAPWIP---------------------------------DKATDICMRCTQTR 165
S + +P +P DK C C +T
Sbjct: 486 SQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAAGLEPRKLSSKTRRDKEKQSCKSCGETF 545
Query: 166 FSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGA 225
S RRHHC+ CG V+C +CS + R S RVC C+ Q E+ E+
Sbjct: 546 NSITKRRHHCKLCGAVICGKCSEFKAENSRQS----RVCRDCF---LTQPVAPESTEKTP 598
Query: 226 GSPGQPAHLARPICGASSGD 245
+ QP+ L P+ + SG+
Sbjct: 599 TADPQPSLLCGPLRLSESGE 618
Score = 30.0 bits (66), Expect = 2.3
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 75 RSQHIIPLEEVTLELLP--ETLQAKNRWMIKTAKKSFVVSAASATERQEWI 123
R IPL L + E L + + W ++ AK+S+ +SA+SA +Q+W+
Sbjct: 645 RLPRTIPLPSCKLSVPDPEERLDSGHVWKLQWAKQSWYLSASSAELQQQWL 695
>gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 57.8 bits (138), Expect = 1e-08
Identities = 61/260 (23%), Positives = 105/260 (40%), Gaps = 54/260 (20%)
Query: 32 PGRVLLGEGVLTKECRKKAKP--RIFFLFNDILVY--GSIVLNKRKYRSQHIIPLEEVTL 87
P L+ EG + K K P R FLFN +++Y + L +K+ + + + + +
Sbjct: 367 PANELIKEGQIQKLSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDISGLQV 426
Query: 88 ELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVRRQ------LRATGRPP 141
+ + + A + ++I K+S + + E++EWI I+ + + +A G
Sbjct: 427 QDIVKPNTA-HTFIITGRKRSLELQTRTEEEKKEWIQIIQATIEKHKQNSETFKAFGGAF 485
Query: 142 STEH---AAPWIP---------------------------------DKATDICMRCTQTR 165
S + +P +P DK C C +T
Sbjct: 486 SQDEDPSLSPDMPITSTSPVEPVVTTEGSSGAAGLEPRKLSSKTRRDKEKQSCKSCGETF 545
Query: 166 FSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCYRELAAQQRQEEAEEQGA 225
S RRHHC+ CG V+C +CS + R S RVC C+ Q E+ E+
Sbjct: 546 NSITKRRHHCKLCGAVICGKCSEFKAENSRQS----RVCRDCF---LTQPVAPESTEKTP 598
Query: 226 GSPGQPAHLARPICGASSGD 245
+ QP+ L P+ + SG+
Sbjct: 599 TADPQPSLLCGPLRLSESGE 618
Score = 30.0 bits (66), Expect = 2.3
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 75 RSQHIIPLEEVTLELLP--ETLQAKNRWMIKTAKKSFVVSAASATERQEWI 123
R IPL L + E L + + W ++ AK+S+ +SA+SA +Q+W+
Sbjct: 645 RLPRTIPLPSCKLSVPDPEERLDSGHVWKLQWAKQSWYLSASSAELQQQWL 695
>gi|5031633 FERM, RhoGEF, and pleckstrin domain protein 1 isoform 1
[Homo sapiens]
Length = 1045
Score = 56.6 bits (135), Expect = 2e-08
Identities = 36/125 (28%), Positives = 65/125 (52%), Gaps = 3/125 (2%)
Query: 29 LALPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSIVLN-KRKYRSQHIIPLEEVTL 87
L +PGR + G L+K K + R+FFLFND+L+Y S L +++ +PL +T+
Sbjct: 753 LVVPGREFIRLGSLSKLSGKGLQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTI 812
Query: 88 ELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVRRQLRATGRPPSTEHAA 147
E + + ++ ++S +V+A+S +E ++W+ I+ + L P+ E A
Sbjct: 813 EESEDEWGVPHCLTLRGQRQSIIVAASSRSEMEKWVEDIQMAI--DLAEKSSSPAPEFLA 870
Query: 148 PWIPD 152
PD
Sbjct: 871 SSPPD 875
>gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo
sapiens]
Length = 1054
Score = 56.6 bits (135), Expect = 2e-08
Identities = 31/104 (29%), Positives = 59/104 (56%), Gaps = 1/104 (0%)
Query: 29 LALPGRVLLGEGVLTKECRKKAKPRIFFLFNDILVYGSI-VLNKRKYRSQHIIPLEEVTL 87
L PGR + EG L K +K + R+FFLF+D+L+Y S V +R + ++PL+ + +
Sbjct: 749 LIAPGREFIREGCLHKLTKKGLQQRMFFLFSDMLLYTSKGVAGTSHFRIRGLLPLQGMLV 808
Query: 88 ELLPETLQAKNRWMIKTAKKSFVVSAASATERQEWISHIEECVR 131
E + + I A+K+ VV+A++ E+++W+ + ++
Sbjct: 809 EESDNEWSVPHCFTIYAAQKTIVVAASTRLEKEKWMLDLNSAIQ 852
>gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform 1
[Homo sapiens]
Length = 1170
Score = 54.3 bits (129), Expect = 1e-07
Identities = 23/52 (44%), Positives = 33/52 (63%), Gaps = 2/52 (3%)
Query: 158 CMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLS-PKPVRVCSLCY 208
C CT RF TR+HHCR CG ++C +CS + + + KPVRVC++C+
Sbjct: 1111 CYECT-ARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNICF 1161
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 54.3 bits (129), Expect = 1e-07
Identities = 25/64 (39%), Positives = 33/64 (51%), Gaps = 2/64 (3%)
Query: 149 WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSP-KPVRVCSLC 207
W+PD C C + F +R+HHCR CG V C+ C Q+ +P +P RVC C
Sbjct: 1079 WLPDHLAAHCYAC-DSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSC 1137
Query: 208 YREL 211
Y L
Sbjct: 1138 YSSL 1141
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,042,134
Number of Sequences: 37866
Number of extensions: 593084
Number of successful extensions: 3141
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 2945
Number of HSP's gapped (non-prelim): 180
length of query: 279
length of database: 18,247,518
effective HSP length: 101
effective length of query: 178
effective length of database: 14,423,052
effective search space: 2567303256
effective search space used: 2567303256
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.