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Search of human proteins with 153266866
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
precursor [Homo sapiens]
(490 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2 prec... 997 0.0
gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Hom... 668 0.0
gi|157743288 gamma-aminobutyric acid (GABA) receptor, rho 3 [Hom... 545 e-155
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 324 1e-88
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 324 1e-88
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 317 1e-86
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 315 6e-86
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre... 306 4e-83
gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is... 295 5e-80
gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo s... 288 8e-78
gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens] 276 4e-74
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 275 5e-74
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 275 5e-74
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 274 2e-73
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 272 6e-73
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 270 2e-72
gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo... 266 3e-71
gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens] 258 7e-69
gi|8924258 gamma-aminobutyric acid (GABA) receptor, theta precur... 254 1e-67
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 253 2e-67
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 248 1e-65
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso... 248 1e-65
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 247 2e-65
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 240 2e-63
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 239 4e-63
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 239 4e-63
gi|4504023 glycine receptor, beta [Homo sapiens] 239 4e-63
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ... 238 7e-63
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 234 1e-61
gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon p... 233 2e-61
>gi|153266866 gamma-aminobutyric acid (GABA) receptor, rho 2
precursor [Homo sapiens]
Length = 490
Score = 997 bits (2578), Expect = 0.0
Identities = 490/490 (100%), Positives = 490/490 (100%)
Query: 1 MVKPGGICSATGYWKAAFCLTDVHKMPYFTRLILFLFCLMVLVESRKPKRKRWTGQVEMP 60
MVKPGGICSATGYWKAAFCLTDVHKMPYFTRLILFLFCLMVLVESRKPKRKRWTGQVEMP
Sbjct: 1 MVKPGGICSATGYWKAAFCLTDVHKMPYFTRLILFLFCLMVLVESRKPKRKRWTGQVEMP 60
Query: 61 KPSHLYKKNLDVTKIRKGKPQQLLRVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVD 120
KPSHLYKKNLDVTKIRKGKPQQLLRVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVD
Sbjct: 61 KPSHLYKKNLDVTKIRKGKPQQLLRVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVD 120
Query: 121 MDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDN 180
MDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDN
Sbjct: 121 MDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDN 180
Query: 181 IMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDE 240
IMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDE
Sbjct: 181 IMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDE 240
Query: 241 SLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLM 300
SLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLM
Sbjct: 241 SLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLM 300
Query: 301 VMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFV 360
VMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFV
Sbjct: 301 VMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFV 360
Query: 361 FLSVLEYAAVNYLTTVQERKERKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRS 420
FLSVLEYAAVNYLTTVQERKERKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRS
Sbjct: 361 FLSVLEYAAVNYLTTVQERKERKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRS 420
Query: 421 HILTEEERQDKIVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIF 480
HILTEEERQDKIVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIF
Sbjct: 421 HILTEEERQDKIVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIF 480
Query: 481 FNLIYWSVFS 490
FNLIYWSVFS
Sbjct: 481 FNLIYWSVFS 490
>gi|194097386 gamma-aminobutyric acid (GABA) receptor, rho 1 [Homo
sapiens]
Length = 479
Score = 668 bits (1724), Expect = 0.0
Identities = 331/445 (74%), Positives = 380/445 (85%), Gaps = 7/445 (1%)
Query: 47 KPKRKRWTGQVEMPKP-SHLYKKNLDVTKIRKGKPQQLLRVDEHDFSMRPAFGGPAIPVG 105
+P+R+R + K S + +++ D+TK K +QLLR+D+HDFSMRP FGGPAIPVG
Sbjct: 41 RPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLRIDDHDFSMRPGFGGPAIPVG 100
Query: 106 VDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFDGRLVKKIWVPDVFF 165
VDVQVESLDSISEVDMDFTMTLYLRHYWKDERL+F S +N SMTFDGRLVKKIWVPD+FF
Sbjct: 101 VDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPSTNNLSMTFDGRLVKKIWVPDMFF 160
Query: 166 VHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYA 225
VHSKRSF HDTTTDN+MLRV PDG VLYS+R+TVTAMCNMDFS FPLD+QTCSLE+ESYA
Sbjct: 161 VHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYA 220
Query: 226 YTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRH 285
YT++DLMLYWK G++SLKTDE+ISLSQFLIQ+FHTT++LAFYSSTGWYNRLYINFTLRRH
Sbjct: 221 YTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYINFTLRRH 280
Query: 286 IFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSY 345
IFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARV LGITTVLTM+TIITGVNASMPRVSY
Sbjct: 281 IFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSY 340
Query: 346 VKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKFPCMCGMLHSKTMMLDGS 405
+KAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKE+KLREK PC G+ +T MLDG+
Sbjct: 341 IKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLPCTSGLPPPRTAMLDGN 400
Query: 406 YSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHA 465
YS+ E N L Y + E+ D+++V L L+ E ++ ++K RI +THA
Sbjct: 401 YSDGEVNDLDNY----MPENGEKPDRMMVQLTLASERSSPQRKSQRSSYVSMRI--DTHA 454
Query: 466 IDKYSRLIFPASYIFFNLIYWSVFS 490
IDKYSR+IFPA+YI FNLIYWS+FS
Sbjct: 455 IDKYSRIIFPAAYILFNLIYWSIFS 479
>gi|157743288 gamma-aminobutyric acid (GABA) receptor, rho 3 [Homo
sapiens]
Length = 467
Score = 545 bits (1404), Expect = e-155
Identities = 275/461 (59%), Positives = 342/461 (74%), Gaps = 4/461 (0%)
Query: 29 FTRLILFLFCLMVLVESRKPKRKRWTGQVEMPKPSHLYKKNLDVTKIRKGKPQQLLRVDE 88
FT + + L + + K +R + ++ K D TK R K +QLL +++
Sbjct: 10 FTYIWIILKPNVCAASNIKMTHQRCSSSMKQTCKQETRMKKDDSTKARPQKYEQLLHIED 69
Query: 89 HDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSM 148
+DF+MRP FGG +PVG+DV VES+DSISE +MDFTMT YLRHYWKDERL+F S +NKSM
Sbjct: 70 NDFAMRPGFGGSPVPVGIDVHVESIDSISETNMDFTMTFYLRHYWKDERLSFPSTANKSM 129
Query: 149 TFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFS 208
TFD RL +KIWVPD+FFVHSKRSF HDTT +NIMLRV PDG+VL S+RITV+AMC MDFS
Sbjct: 130 TFDHRLTRKIWVPDIFFVHSKRSFIHDTTMENIMLRVHPDGNVLLSLRITVSAMCFMDFS 189
Query: 209 HFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYS 268
FPLD+Q CSLELESYAY ++DLMLYWK+G++SL T+E +SLSQF I+ F +S LAFYS
Sbjct: 190 RFPLDTQNCSLELESYAYNEDDLMLYWKHGNKSLNTEEHMSLSQFFIEDFSASSGLAFYS 249
Query: 269 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLT 328
STGWYNRL+INF LRRH+FFF+LQTYFPA LMVMLSWVSFWIDRRAVPARVSLGITTVLT
Sbjct: 250 STGWYNRLFINFVLRRHVFFFVLQTYFPAILMVMLSWVSFWIDRRAVPARVSLGITTVLT 309
Query: 329 MTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKF 388
M+TIIT V+ASMP+VSY+KAVD+YLWVS +FVFLSV+EYAAVNYLTTV+ERK+ K K
Sbjct: 310 MSTIITAVSASMPQVSYLKAVDVYLWVSSLFVFLSVIEYAAVNYLTTVEERKQFKKTGKI 369
Query: 389 PCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAARKK 448
M + + M DG Y +SE + + +E+ + K + S +++ +++
Sbjct: 370 SRMYNIDAVQAMAFDGCYHDSEID--MDQTSLSLNSEDFMRRKSI--CSPSTDSSRIKRR 425
Query: 449 GLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
L G G I +N H ID YSR++FP YI FNL YW V+
Sbjct: 426 KSLGGHVGRIILENNHVIDTYSRILFPIVYILFNLFYWGVY 466
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 324 bits (831), Expect = 1e-88
Identities = 172/434 (39%), Positives = 262/434 (60%), Gaps = 49/434 (11%)
Query: 89 HDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSM 148
+D +RP FGGP + VG+++ + S+D +SEV+MD+T+T+Y + YW+D+RLA+S ++
Sbjct: 48 YDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIP-LNL 106
Query: 149 TFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFS 208
T D R+ ++WVPD +F++ K+SF H T N M+R+ PDG VLY +RIT TA C MD
Sbjct: 107 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 166
Query: 209 HFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYS 268
+PLD Q C+LE+ESY YT +D+ YW+ GD+++ E+I L QF I + SR ++
Sbjct: 167 RYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFA 226
Query: 269 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLT 328
TG Y RL ++F L+R+I +F+LQTY P+ L+ +LSWVSFWI+ A ARV+LGITTVLT
Sbjct: 227 -TGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 285
Query: 329 MTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQ-ERKERKLREK 387
MTTI T + ++P++ YVKA+D+YL FVFVFL++LEYA VNY+ + ++++KL E
Sbjct: 286 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAE- 344
Query: 388 FPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAA-- 445
KT S+SE+N + + + + E + V G+ N+A
Sbjct: 345 ----------KTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAIS 394
Query: 446 -----------------------------RKKGLLKGQTGFRI----FQNTHAIDKYSRL 472
+K L + + +I + +AID++SR+
Sbjct: 395 FDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRI 454
Query: 473 IFPASYIFFNLIYW 486
+FP ++ FNL+YW
Sbjct: 455 VFPFTFSLFNLVYW 468
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 324 bits (831), Expect = 1e-88
Identities = 172/434 (39%), Positives = 262/434 (60%), Gaps = 49/434 (11%)
Query: 89 HDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSM 148
+D +RP FGGP + VG+++ + S+D +SEV+MD+T+T+Y + YW+D+RLA+S ++
Sbjct: 48 YDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIP-LNL 106
Query: 149 TFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFS 208
T D R+ ++WVPD +F++ K+SF H T N M+R+ PDG VLY +RIT TA C MD
Sbjct: 107 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 166
Query: 209 HFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYS 268
+PLD Q C+LE+ESY YT +D+ YW+ GD+++ E+I L QF I + SR ++
Sbjct: 167 RYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFA 226
Query: 269 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLT 328
TG Y RL ++F L+R+I +F+LQTY P+ L+ +LSWVSFWI+ A ARV+LGITTVLT
Sbjct: 227 -TGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 285
Query: 329 MTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQ-ERKERKLREK 387
MTTI T + ++P++ YVKA+D+YL FVFVFL++LEYA VNY+ + ++++KL E
Sbjct: 286 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAE- 344
Query: 388 FPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAA-- 445
KT S+SE+N + + + + E + V G+ N+A
Sbjct: 345 ----------KTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAIS 394
Query: 446 -----------------------------RKKGLLKGQTGFRI----FQNTHAIDKYSRL 472
+K L + + +I + +AID++SR+
Sbjct: 395 FDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRI 454
Query: 473 IFPASYIFFNLIYW 486
+FP ++ FNL+YW
Sbjct: 455 VFPFTFSLFNLVYW 468
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 317 bits (813), Expect = 1e-86
Identities = 167/426 (39%), Positives = 254/426 (59%), Gaps = 32/426 (7%)
Query: 89 HDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSM 148
+D +RP FGGP + VG+ + V S+D +SEV+MD+T+T+Y + WKD+RL++S ++
Sbjct: 48 YDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIP-LNL 106
Query: 149 TFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFS 208
T D R+ ++WVPD +F++ K+SF H T N M+R+ PDG VLY +RIT TA C MD
Sbjct: 107 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 166
Query: 209 HFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYS 268
+PLD Q C+LE+ESY YT +D+ YW G+ ++ KI L QF I + S+ ++
Sbjct: 167 RYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFT 226
Query: 269 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLT 328
TG Y RL ++F L+R+I +F+LQTY P+TL+ +LSWVSFWI+ A ARV+LGITTVLT
Sbjct: 227 -TGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLT 285
Query: 329 MTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYL--------------- 373
MTTI T + ++P++ YVKA+DIYL FVFVFL++LEYA VNY+
Sbjct: 286 MTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQD 345
Query: 374 TTVQERKERKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHI----------- 422
+ E+ + ++ + G + T+ + S SE + P++ +
Sbjct: 346 QSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYR 405
Query: 423 --LTEEERQDKIVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIF 480
L+ E + + G+ + R+ LK + ++IDK+SR+ FP ++
Sbjct: 406 KPLSSREAYGRALDRHGVPSKGRIRRRASQLK--VKIPDLTDVNSIDKWSRMFFPITFSL 463
Query: 481 FNLIYW 486
FN++YW
Sbjct: 464 FNVVYW 469
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 315 bits (807), Expect = 6e-86
Identities = 171/429 (39%), Positives = 262/429 (61%), Gaps = 37/429 (8%)
Query: 89 HDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSM 148
+D +RP FGGP + VG+++ + S+D +SEV+MD+T+T+Y + W+D+RL+++ ++
Sbjct: 47 YDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIP-LNL 105
Query: 149 TFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFS 208
T D R+ ++WVPD +F++ K+SF H T N M+R+ PDG VLY +RIT TA C MD
Sbjct: 106 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 165
Query: 209 HFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYS 268
+PLD Q C+LE+ESY YT +D+ YW+ D ++ KI L QF I + ++ +S
Sbjct: 166 RYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFS 225
Query: 269 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLT 328
TG Y RL ++F L+R+I +F+LQTY P+ L+ +LSWVSFWI+ A ARV+LGITTVLT
Sbjct: 226 -TGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 284
Query: 329 MTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQ-ERKERKLREK 387
MTTI T + ++P++ YVKA+D+YL FVFVF+++LEYA VNY+ + ++++K EK
Sbjct: 285 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEK 344
Query: 388 FPCMCGMLHSKTMMLD------------------GSYSESEANSLAGYPRSHILTEEE-- 427
+++ M LD + SEA G PRS +L +
Sbjct: 345 ----AASANNEKMRLDVNKMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASS 400
Query: 428 ---RQDKIVVH-LGLSG-EANAARKKGLLKGQTG-----FRIFQNTHAIDKYSRLIFPAS 477
R+ + H G + E + A+KK L+ + + +AID++SR+ FP
Sbjct: 401 IQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVV 460
Query: 478 YIFFNLIYW 486
+ FFN++YW
Sbjct: 461 FSFFNIVYW 469
>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
precursor [Homo sapiens]
Length = 452
Score = 306 bits (783), Expect = 4e-83
Identities = 150/407 (36%), Positives = 255/407 (62%), Gaps = 17/407 (4%)
Query: 92 SMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFD 151
+ RP GGP + V + ++V S+D ISE +M++TMT++L W+D RL+++ +N+++ D
Sbjct: 54 NFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYNH-TNETLGLD 112
Query: 152 GRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFP 211
R V K+W+PD F V++K ++ HD T +N ++R+ PDG +LYS+RIT T C+MD + +P
Sbjct: 113 SRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYP 172
Query: 212 LDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTG 271
+D Q C L+LESY Y+ ED++ YW E + +K+ L+QF I + T+ L + S G
Sbjct: 173 MDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAG 232
Query: 272 WYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTT 331
+ RL ++F LRR+ +++Q+Y P+ L+V +SWVSFWI + AVPARVSLGITTVLTMTT
Sbjct: 233 QFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTT 292
Query: 332 IITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKFPCM 391
++ +S+PR S +KA+D+Y W+ +VFVF +++EYA ++ +++++ K++ P
Sbjct: 293 LMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAKVKVSRPRA 352
Query: 392 CGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQ---DKIVVHLGLSGEANAARKK 448
+ + ++ + S AG + ++ +R+ + + + + E +K+
Sbjct: 353 EMDVRNAIVLF--------SLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVETGETKKE 404
Query: 449 GLLK--GQTGFRIFQ---NTHAIDKYSRLIFPASYIFFNLIYWSVFS 490
G + GQ G R + ID Y+R +FPA++ N+IYW+ ++
Sbjct: 405 GAARSGGQGGIRARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAYA 451
>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 1 [Homo sapiens]
Length = 512
Score = 295 bits (756), Expect = 5e-80
Identities = 140/300 (46%), Positives = 210/300 (70%), Gaps = 3/300 (1%)
Query: 89 HDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSM 148
+D +RP FGGP + VG+++ + S+D +SEV+MD+T+T+Y + W+D+RL+++ ++
Sbjct: 47 YDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIP-LNL 105
Query: 149 TFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFS 208
T D R+ ++WVPD +F++ K+SF H T N M+R+ PDG VLY +RIT TA C MD
Sbjct: 106 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR 165
Query: 209 HFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYS 268
+PLD Q C+LE+ESY YT +D+ YW+ D ++ KI L QF I + ++ +S
Sbjct: 166 RYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFS 225
Query: 269 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLT 328
TG Y RL ++F L+R+I +F+LQTY P+ L+ +LSWVSFWI+ A ARV+LGITTVLT
Sbjct: 226 -TGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 284
Query: 329 MTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQ-ERKERKLREK 387
MTTI T + ++P++ YVKA+D+YL FVFVF+++LEYA VNY+ + ++++K EK
Sbjct: 285 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEK 344
Score = 38.1 bits (87), Expect = 0.018
Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 12/100 (12%)
Query: 399 TMMLDGSYSESEANSLAGYPRSHILTEEE-----RQDKIVVH-LGLSG-EANAARKKGLL 451
T+ + + SEA G PRS +L + R+ + H G + E + A+KK L
Sbjct: 408 TLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRL 467
Query: 452 KGQTG-----FRIFQNTHAIDKYSRLIFPASYIFFNLIYW 486
+ + + +AID++SR+ FP + FFN++YW
Sbjct: 468 RRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYW 507
>gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo
sapiens]
Length = 440
Score = 288 bits (737), Expect = 8e-78
Identities = 150/399 (37%), Positives = 239/399 (59%), Gaps = 15/399 (3%)
Query: 93 MRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFDG 152
+RP FGG + + + + + S+ SISE +MD+T T+YLR W D+RL F NKS T D
Sbjct: 52 LRPNFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVFEG--NKSFTLDA 109
Query: 153 RLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPL 212
RLV+ +WVPD + V SK+SF H+ T N ++R+F +G VLY++RIT T CNMD S +P+
Sbjct: 110 RLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPM 169
Query: 213 DSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGW 272
D+QTC L+LES+ Y D+ W G++S++ E + L+Q+ I+++ T + TG
Sbjct: 170 DTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRS-QQETGN 228
Query: 273 YNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTI 332
Y RL + F LRR++ +F+L+TY P+T +V+LSWVSFWI +VPAR +G+TTVL+MTT+
Sbjct: 229 YTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTL 288
Query: 333 ITGVNASMPRVS-YVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQ-ERKERKLREKFPC 390
+ G S+P + ++KA+D+YL + F FVF ++LEYA +Y + Q K+R ++
Sbjct: 289 MIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDRGTTKEVEE 348
Query: 391 MCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAARKKGL 450
+ S T +++ S S + + I ++ + + + K G
Sbjct: 349 V-----SITNIINSSISSFKRK--ISFASIEISSDNVDYSDLTMKTSDKFKFVFREKMGR 401
Query: 451 LKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
+ + QN +D YS+L+FP ++ N+ YW+ +
Sbjct: 402 I---VDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYY 437
>gi|169646728 glycine receptor, alpha 2 isoform B [Homo sapiens]
Length = 452
Score = 276 bits (705), Expect = 4e-74
Identities = 149/405 (36%), Positives = 233/405 (57%), Gaps = 17/405 (4%)
Query: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
R +D +RP F GP + V ++ + S SI+E MD+ + ++LR W D RLA+S
Sbjct: 54 RTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYP 113
Query: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
+ S+ D ++ IW PD+FF + K + HD TTDN +LR+ +G VLYS+R+T+T C
Sbjct: 114 DDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCP 173
Query: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
MD +FP+D QTC+++LES+ YT DL+ W + D ++ E ++L QF++++
Sbjct: 174 MDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLS-DGPVQVAEGLTLPQFILKEEKELGYC 232
Query: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
+ +TG + + + F L R + ++L+Q Y P+ L+V+LSWVSFWI+ A PARV+LGIT
Sbjct: 233 TKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGIT 292
Query: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKL 384
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ Q ++ +L
Sbjct: 293 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR-QHKEFLRL 351
Query: 385 REKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANA 444
R + K + + + +GY H L + +D V +
Sbjct: 352 RRR---------QKRQNKEEDVTRESRFNFSGYGMGHCL---QVKDGTAVKATPANPLPQ 399
Query: 445 ARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
K G + ID SR FP +++ FN+ YW +
Sbjct: 400 PPKDG---DAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 275 bits (704), Expect = 5e-74
Identities = 148/405 (36%), Positives = 233/405 (57%), Gaps = 17/405 (4%)
Query: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
R +D +RP F GP + V ++ + S S++E MD+ + ++LR W D RLA+S
Sbjct: 54 RTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYP 113
Query: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
+ S+ D ++ IW PD+FF + K + HD TTDN +LR+ +G VLYS+R+T+T C
Sbjct: 114 DDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCP 173
Query: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
MD +FP+D QTC+++LES+ YT DL+ W + D ++ E ++L QF++++
Sbjct: 174 MDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLS-DGPVQVAEGLTLPQFILKEEKELGYC 232
Query: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
+ +TG + + + F L R + ++L+Q Y P+ L+V+LSWVSFWI+ A PARV+LGIT
Sbjct: 233 TKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGIT 292
Query: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKL 384
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ Q ++ +L
Sbjct: 293 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR-QHKEFLRL 351
Query: 385 REKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANA 444
R + K + + + +GY H L + +D V +
Sbjct: 352 RRR---------QKRQNKEEDVTRESRFNFSGYGMGHCL---QVKDGTAVKATPANPLPQ 399
Query: 445 ARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
K G + ID SR FP +++ FN+ YW +
Sbjct: 400 PPKDG---DAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 275 bits (704), Expect = 5e-74
Identities = 148/405 (36%), Positives = 233/405 (57%), Gaps = 17/405 (4%)
Query: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
R +D +RP F GP + V ++ + S S++E MD+ + ++LR W D RLA+S
Sbjct: 54 RTSGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYP 113
Query: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
+ S+ D ++ IW PD+FF + K + HD TTDN +LR+ +G VLYS+R+T+T C
Sbjct: 114 DDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCP 173
Query: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
MD +FP+D QTC+++LES+ YT DL+ W + D ++ E ++L QF++++
Sbjct: 174 MDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLS-DGPVQVAEGLTLPQFILKEEKELGYC 232
Query: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
+ +TG + + + F L R + ++L+Q Y P+ L+V+LSWVSFWI+ A PARV+LGIT
Sbjct: 233 TKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGIT 292
Query: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKL 384
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ Q ++ +L
Sbjct: 293 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSR-QHKEFLRL 351
Query: 385 REKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANA 444
R + K + + + +GY H L + +D V +
Sbjct: 352 RRR---------QKRQNKEEDVTRESRFNFSGYGMGHCL---QVKDGTAVKATPANPLPQ 399
Query: 445 ARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
K G + ID SR FP +++ FN+ YW +
Sbjct: 400 PPKDG---DAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 274 bits (700), Expect = 2e-73
Identities = 150/410 (36%), Positives = 236/410 (57%), Gaps = 16/410 (3%)
Query: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
R +D +RP F GP + V ++ + S SI+E MD+ + ++LR W D RLA+S
Sbjct: 53 RTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP 112
Query: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
+ S+ D ++ IW PD+FF + K + H+ TTDN +LR+F +G+VLYS+R+T+T C
Sbjct: 113 DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCP 172
Query: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
MD +FP+D QTC ++LES+ YT DL+ W++ + ++ E ++L QFL+++
Sbjct: 173 MDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVAEGLTLPQFLLKEEKDLRYC 231
Query: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
+ +TG + + + F L R + ++L+Q Y P+ L+V+LSWVSFWI+ A PARV+LGIT
Sbjct: 232 TKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGIT 291
Query: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQE---RKE 381
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ + R
Sbjct: 292 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFR 351
Query: 382 RKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGE 441
RK + K + +D ES S Y L ++ G++ +
Sbjct: 352 RKRKNKTEAFALEKFYRFSDMDDEVRESRF-SFTAYGMGPCLQAKD---------GMTPK 401
Query: 442 ANAARKKGLLKGQTGFR--IFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
+ + K R ID SR FP +++ FN+ YW ++
Sbjct: 402 GPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 272 bits (695), Expect = 6e-73
Identities = 151/410 (36%), Positives = 238/410 (58%), Gaps = 16/410 (3%)
Query: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
R +D +RP F GP + V ++ + S SI+E MD+ + ++LR W D RLA++
Sbjct: 48 RTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP 107
Query: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
+ S+ D ++ IW PD+FF + K + H+ TTDN +LR+ +G+VLYS+RIT+T C
Sbjct: 108 DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACP 167
Query: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
MD +FP+D QTC ++LES+ YT DL+ W+ +++ + ++L QF++++
Sbjct: 168 MDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVADGLTLPQFILKEEKDLRYC 226
Query: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
+ +TG + + F L R + ++L+Q Y P+ L+V+LSW+SFWI+ A PARV LGIT
Sbjct: 227 TKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGIT 286
Query: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKL 384
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ Q ++ +
Sbjct: 287 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSR-QHKELLRF 345
Query: 385 REKFPCMCGMLHSKTMMLDGSYSESEAN----SLAGYPRSHILTEEERQDKIVVH-LGLS 439
R K H K+ ML+ + E EA + + Y + +D I V S
Sbjct: 346 RRK------RRHHKSPMLN-LFQEDEAGEGRFNFSAYGMGPACL--QAKDGISVKGANNS 396
Query: 440 GEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
N + Q IDK SR+ FP +++ FN+ YW ++
Sbjct: 397 NTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 270 bits (690), Expect = 2e-72
Identities = 149/407 (36%), Positives = 234/407 (57%), Gaps = 25/407 (6%)
Query: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
R +D +RP F GP + V ++ + S SI+E MD+ + ++LR W D RLA+S
Sbjct: 53 RTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYP 112
Query: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
+ S+ D ++ IW PD+FF + K + H+ TTDN +LR+F +G+VLYS+R+T+T C
Sbjct: 113 DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCP 172
Query: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
MD +FP+D QTC ++LES+ YT DL+ W++ + ++ E ++L QFL+++
Sbjct: 173 MDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVAEGLTLPQFLLKEEKDLRYC 231
Query: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
+ +TG + + + F L R + ++L+Q Y P+ L+V+LSWVSFWI+ A PARV+LGIT
Sbjct: 232 TKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGIT 291
Query: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKL 384
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ R+ ++L
Sbjct: 292 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVS----RQHKEL 347
Query: 385 REKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANA 444
K D ES S Y L ++ G++ +
Sbjct: 348 LR--------FRRKRKNKDDEVRESRF-SFTAYGMGPCLQAKD---------GMTPKGPN 389
Query: 445 ARKKGLLKGQTGFR--IFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
+ + K R ID SR FP +++ FN+ YW ++
Sbjct: 390 HPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 436
>gi|119372310 glycine receptor, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 449
Score = 266 bits (680), Expect = 3e-71
Identities = 149/418 (35%), Positives = 232/418 (55%), Gaps = 40/418 (9%)
Query: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
R +D +RP F GP + V ++ + S SI+E MD+ + ++LR W D RLA++
Sbjct: 48 RTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYP 107
Query: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
+ S+ D ++ IW PD+FF + K + H+ TTDN +LR+ +G+VLYS+RIT+T C
Sbjct: 108 DDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACP 167
Query: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
MD +FP+D QTC ++LES+ YT DL+ W+ +++ + ++L QF++++
Sbjct: 168 MDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQE-QGAVQVADGLTLPQFILKEEKDLRYC 226
Query: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
+ +TG + + F L R + ++L+Q Y P+ L+V+LSW+SFWI+ A PARV LGIT
Sbjct: 227 TKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGIT 286
Query: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQE------ 378
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAAVN+++ +
Sbjct: 287 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFR 346
Query: 379 RKERKLRE------KFPCMC-GMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDK 431
RK R +E +F GM + DG + NS P E K
Sbjct: 347 RKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRK 406
Query: 432 IVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
+ + Q IDK SR+ FP +++ FN+ YW ++
Sbjct: 407 LFI--------------------------QRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
>gi|218156328 glycine receptor, alpha 4 precursor [Homo sapiens]
Length = 417
Score = 258 bits (660), Expect = 7e-69
Identities = 124/303 (40%), Positives = 199/303 (65%), Gaps = 1/303 (0%)
Query: 85 RVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSAS 144
R +D +RP F GP + V ++ + S SI++ MD+ + ++LR W D RL++
Sbjct: 54 RTSGYDARIRPNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYREYP 113
Query: 145 NKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCN 204
+ S+ D ++ IW PD+FF + K + H+ TTDN +LR+F +G+VLYS+R+T+ C
Sbjct: 114 DDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCL 173
Query: 205 MDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRL 264
MD +FP+D QTC+++LES+ YT +DL+ W +++ E ++L QF+++
Sbjct: 174 MDLKNFPMDIQTCTMQLESFGYTMKDLVFEWLEDAPAVQVAEGLTLPQFILRDEKDLGCC 233
Query: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
+ +TG + + + F L R + ++L+Q Y P+ L+V+LSWVSFWI+ A PARV LGIT
Sbjct: 234 TKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGIT 293
Query: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKL 384
TVLTMTT +G AS+P+VSYVKA+DI++ V +FVF ++LEYAA+N+++ Q ++ +L
Sbjct: 294 TVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAINFVSR-QHKEFIRL 352
Query: 385 REK 387
R +
Sbjct: 353 RRR 355
>gi|8924258 gamma-aminobutyric acid (GABA) receptor, theta precursor
[Homo sapiens]
Length = 632
Score = 254 bits (649), Expect = 1e-67
Identities = 118/305 (38%), Positives = 198/305 (64%), Gaps = 4/305 (1%)
Query: 86 VDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASN 145
+ +D +RP FGG +PV + + V S++ ISE++MD+T+T++ WKD RLA+ +
Sbjct: 67 LSRYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAYYETT- 125
Query: 146 KSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNM 205
++T D R+ +K+WVPD +F++SK +F HD T +N + ++ PDG V Y +R+T TA C++
Sbjct: 126 LNLTLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSL 185
Query: 206 DFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQF-LIQKFHTTSRL 264
D FP+D Q C+L +ESY YT ED++L+W + ++ E++ + QF + + T+ +
Sbjct: 186 DLHKFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEV 245
Query: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
FY TG Y RL + F ++R + +L+Q Y+P L + SW+SFW++ + ARV++G+T
Sbjct: 246 YFY--TGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLT 303
Query: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKL 384
++L +TTI + + +P +S +KA+DIY+ V FVFLS+LEY +NYL + + +
Sbjct: 304 SMLILTTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPR 363
Query: 385 REKFP 389
R + P
Sbjct: 364 RHRRP 368
Score = 33.1 bits (74), Expect = 0.59
Identities = 10/21 (47%), Positives = 17/21 (80%)
Query: 466 IDKYSRLIFPASYIFFNLIYW 486
+DK+SR +FP ++ FN++YW
Sbjct: 607 VDKWSRFLFPLAFGLFNIVYW 627
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 253 bits (647), Expect = 2e-67
Identities = 149/414 (35%), Positives = 234/414 (56%), Gaps = 23/414 (5%)
Query: 86 VDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASN 145
++ +D +RP FGG V D+ V S +S+V+M++TM ++ R W DERL F +
Sbjct: 40 LEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPT- 98
Query: 146 KSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNM 205
+ ++ + +V KIW PD FF + K+S H+ TT N + R+ +G +LY+MR+T+ A C M
Sbjct: 99 EILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPM 158
Query: 206 DFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGD-ESLKT-DEKISLSQF-LIQKFHTTS 262
+FP+D C L+ SYAY +++ WK G S++ +E SL Q+ LI + T S
Sbjct: 159 RLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQ--TVS 216
Query: 263 RLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLG 322
S+TG Y + + F L+R + +F++Q Y P + V+LS VSFWI++ +VPAR G
Sbjct: 217 SETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFG 276
Query: 323 ITTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERK-E 381
ITTVLTMTT+ S+P+VSY A+D ++ V F FVF +++E+AAVNY T +Q +K +
Sbjct: 277 ITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAK 336
Query: 382 RKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGE 441
RK + P T+ + + EA + + L ++R + + + S E
Sbjct: 337 RKAQFAAP--------PTVTISKATEPLEAEIVLHPDSKYHL--KKRITSLSLPIVSSSE 386
Query: 442 ANAARKKGLLKGQTGFR------IFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
AN + + T F T ID+YSR++FP ++ FNL+YW V+
Sbjct: 387 ANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVY 440
>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
precursor [Homo sapiens]
Length = 475
Score = 248 bits (632), Expect = 1e-65
Identities = 137/405 (33%), Positives = 226/405 (55%), Gaps = 13/405 (3%)
Query: 86 VDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASN 145
++ +D +RP G + D+ V S+ ++ ++M++T+ ++ W D RL F+S
Sbjct: 74 LEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTI- 132
Query: 146 KSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNM 205
K + + +V KIW+PD FF +SK++ H TT N MLR++ DG VLY++R+T+ A C +
Sbjct: 133 KVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQL 192
Query: 206 DFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLA 265
+FP+D +C LE SY Y E+++ WK + L QF T+ +
Sbjct: 193 QLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVV 252
Query: 266 FYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITT 325
+++G Y + + F L R + +F +QTY P TL+V+LSWVSFWI++ AVPAR SLGITT
Sbjct: 253 -KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITT 311
Query: 326 VLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLR 385
VLTMTT+ T S+P+VSYV A+D+++ V F+FVF +++EY ++Y + ++ + K +
Sbjct: 312 VLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDK 371
Query: 386 EKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAA 445
+K + M K +D + + + T + +D+ + L G+ A+
Sbjct: 372 KKKNPLLRMFSFKAPTID-------IRPRSATIQMNNATHLQERDEEYGYECLDGKDCAS 424
Query: 446 RKKGLLKGQTGF----RIFQNTHAIDKYSRLIFPASYIFFNLIYW 486
+TG RI +D Y+R+ FP ++ FNL+YW
Sbjct: 425 FFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYW 469
>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
[Homo sapiens]
Length = 465
Score = 248 bits (632), Expect = 1e-65
Identities = 145/419 (34%), Positives = 226/419 (53%), Gaps = 23/419 (5%)
Query: 74 KIRKGKPQQLLR--VDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRH 131
KI +G Q+L + +D +RP G + DV V S+ + ++M++T+ +
Sbjct: 58 KIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQ 117
Query: 132 YWKDERLAFSSASNKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHV 191
W D RL F+S K + + +V KIW+PD FF +S++S H TT N +LR++ DG V
Sbjct: 118 TWFDSRLKFNSTM-KVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRV 176
Query: 192 LYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLS 251
LY++R+T+ A C + +FP+D +C LE SY Y ++ WK + + L
Sbjct: 177 LYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLY 236
Query: 252 QFLIQKFHTTSRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWID 311
QF ++ + ++ +G Y + I F L R + +F +QTY P L V+LSWVSFWI+
Sbjct: 237 QFAFVGLRNSTEIT-HTISGDYVIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWIN 295
Query: 312 RRAVPARVSLGITTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVN 371
+ AVPAR SLGITTVLTMTT+ T S+P+VSYV A+D+++ V F+FVF +++EY ++
Sbjct: 296 KDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLH 355
Query: 372 YLTTVQE----RKERKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEE 427
Y T+ Q+ K+RKL+ K G+ T++ + S + + GY E
Sbjct: 356 YFTSNQKGKTATKDRKLKNKASMTPGLHPGSTLIPMNNISVPQEDDY-GYQCL------E 408
Query: 428 RQDKIVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYW 486
+D + ++G RI ID YSR+ FP ++ FNL+YW
Sbjct: 409 GKDCASFFCCFEDCRTGSWREG--------RIHIRIAKIDSYSRIFFPTAFALFNLVYW 459
>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
precursor [Homo sapiens]
Length = 467
Score = 247 bits (630), Expect = 2e-65
Identities = 136/404 (33%), Positives = 221/404 (54%), Gaps = 19/404 (4%)
Query: 86 VDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASN 145
++ +D +RP G + D+ V S+ ++ ++M++T+ ++ W D RL F+S
Sbjct: 74 LEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTI- 132
Query: 146 KSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNM 205
K + + +V KIW+PD FF +SK++ H TT N MLR++ DG VLY++R+T+ A C +
Sbjct: 133 KVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQL 192
Query: 206 DFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLA 265
+FP+D +C LE SY Y E+++ WK + L QF T+ +
Sbjct: 193 QLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVV 252
Query: 266 FYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITT 325
+++G Y + + F L R + +F +QTY P TL+V+LSWVSFWI++ AVPAR SLGITT
Sbjct: 253 -KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITT 311
Query: 326 VLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTT---VQERKER 382
VLTMTT+ T S+P+VSYV A+D+++ V F+FVF +++EY ++Y + + K++
Sbjct: 312 VLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDK 371
Query: 383 KLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEA 442
K + P + S T+ ++ + E + GY + +D
Sbjct: 372 KKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECL------DGKDCASFFCCFEDCR 425
Query: 443 NAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYW 486
A + G RI +D Y+R+ FP ++ FNL+YW
Sbjct: 426 TGAWRHG--------RIHIRIAKMDSYARIFFPTAFCLFNLVYW 461
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 240 bits (612), Expect = 2e-63
Identities = 147/468 (31%), Positives = 240/468 (51%), Gaps = 46/468 (9%)
Query: 34 LFLFCLMVLVESRKPKRKRWTGQVEMPKPSHLYKKNLDVTKIRKGKPQQLLRVDEHDFSM 93
L LFC+ + + S G +MP S + N ++T + L D +D +
Sbjct: 15 LLLFCISMNLSSH-------FGFSQMPTSSVKDETNDNITIFTRILDGLL---DGYDNRL 64
Query: 94 RPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASNKSMTFDGR 153
RP G V D+ V S +S+ +M++T+ ++ R WKDERL F + + +
Sbjct: 65 RPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQR-LPLNNL 123
Query: 154 LVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLD 213
L KIW PD FF + K+S H+ TT N +LR+ DG +LY+MR+T++A C M FP+D
Sbjct: 124 LASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMD 183
Query: 214 SQTCSLELESYAYTDEDLMLYWKNGDES--LKTDEKISLSQFLIQKFHTTSRLAFYSSTG 271
+ C L+ SYAY + +++ W NG + ++ L+Q+ + T +STG
Sbjct: 184 AHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMG-QTVGTENISTSTG 242
Query: 272 WYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTT 331
Y + +F L+R I +F++QTY P + V+LS VSFW++R +VPAR G+TTVLTMTT
Sbjct: 243 EYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTT 302
Query: 332 IITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLT----------TVQERKE 381
+ S+P+V+Y A+D ++ V + FVF +++E+A VNY T ++ K
Sbjct: 303 LSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKI 362
Query: 382 RKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGE 441
+K RE ++L+ S + ++ P + +E+ G S
Sbjct: 363 KKKRE-------------VILNKSTNAFTTGKMSHPPN---IPKEQ------TPAGTSNT 400
Query: 442 ANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
+ + K K + + + IDK SR++FP + FNL+YW+ +
Sbjct: 401 TSVSVKPSEEKTSESKKTYNSISKIDKMSRIVFPVLFGTFNLVYWATY 448
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 239 bits (610), Expect = 4e-63
Identities = 137/416 (32%), Positives = 220/416 (52%), Gaps = 37/416 (8%)
Query: 86 VDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASN 145
+D +D +RP G V ++ V S +S+ DM++T+ ++ R WKDERL F N
Sbjct: 50 LDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMN 109
Query: 146 KSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNM 205
+ + + KIW PD FF + K+S H+ T N +LR+ DG +LY+MR+TV A C M
Sbjct: 110 -ILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPM 168
Query: 206 DFSHFPLDSQTCSLELESYAYTDEDLMLYWK-NGDESLKTDEKIS-LSQFLIQKFHTTSR 263
FP+D+ +C L+ SYAYT ++ W N +S++ S L+Q+ + + +
Sbjct: 169 HLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLG-QSIGK 227
Query: 264 LAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGI 323
SSTG Y + +F L+R I +F++QTY P + V+LS VSFW++R +VPAR G+
Sbjct: 228 ETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGV 287
Query: 324 TTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLT--------- 374
TTVLTMTT+ S+P+V+Y A+D ++ V + FVF +++E+A VNY T
Sbjct: 288 TTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGK 347
Query: 375 -TVQERKERKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIV 433
V ++K+ K + M+ + +Y+ + AN + D ++
Sbjct: 348 SVVNDKKKEK-------------ASVMIQNNAYAVAVANYAPNLSK----------DPVL 384
Query: 434 VHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
+ S KK K + F + ID+ SR++FP + FNL+YW+ +
Sbjct: 385 STISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 239 bits (610), Expect = 4e-63
Identities = 137/416 (32%), Positives = 220/416 (52%), Gaps = 37/416 (8%)
Query: 86 VDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASN 145
+D +D +RP G V ++ V S +S+ DM++T+ ++ R WKDERL F N
Sbjct: 50 LDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMN 109
Query: 146 KSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNM 205
+ + + KIW PD FF + K+S H+ T N +LR+ DG +LY+MR+TV A C M
Sbjct: 110 -ILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPM 168
Query: 206 DFSHFPLDSQTCSLELESYAYTDEDLMLYWK-NGDESLKTDEKIS-LSQFLIQKFHTTSR 263
FP+D+ +C L+ SYAYT ++ W N +S++ S L+Q+ + + +
Sbjct: 169 HLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLG-QSIGK 227
Query: 264 LAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGI 323
SSTG Y + +F L+R I +F++QTY P + V+LS VSFW++R +VPAR G+
Sbjct: 228 ETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGV 287
Query: 324 TTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLT--------- 374
TTVLTMTT+ S+P+V+Y A+D ++ V + FVF +++E+A VNY T
Sbjct: 288 TTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGK 347
Query: 375 -TVQERKERKLREKFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIV 433
V ++K+ K + M+ + +Y+ + AN + D ++
Sbjct: 348 SVVNDKKKEK-------------ASVMIQNNAYAVAVANYAPNLSK----------DPVL 384
Query: 434 VHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYWSVF 489
+ S KK K + F + ID+ SR++FP + FNL+YW+ +
Sbjct: 385 STISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATY 440
>gi|4504023 glycine receptor, beta [Homo sapiens]
Length = 497
Score = 239 bits (610), Expect = 4e-63
Identities = 151/435 (34%), Positives = 237/435 (54%), Gaps = 39/435 (8%)
Query: 89 HDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSS--ASNK 146
+D +RP F G + V V++ + S SI E MD+ + ++LR W D RL S +
Sbjct: 67 YDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDFRGSD 126
Query: 147 SMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMD 206
++T D + K +W PD+FF + K + HD T +NI+L +F DG VL SMR+++T C +D
Sbjct: 127 ALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLD 186
Query: 207 FSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQK--FHTTSRL 264
+ FP+D+Q C ++LES+ YT +DL W++GD EKI+L QF I+K +
Sbjct: 187 LTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQL--EKIALPQFDIKKEDIEYGNCT 244
Query: 265 AFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGIT 324
+Y TG+Y + + FTLRR + F+++ Y P L+V+LSW+SFWI+ A ARV LGI
Sbjct: 245 KYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIF 304
Query: 325 TVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTT----VQERK 380
+VL++ + T + A +P+VSYVKA+D++L +F F S++EYA V + V+ K
Sbjct: 305 SVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEK 364
Query: 381 ERKLREKFPCMCGMLHSKTMMLDGS--------------------YSESEANS-----LA 415
R + + G +K ++G+ S+S+ S +
Sbjct: 365 ARIAKAEQADGKGGNVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVG 424
Query: 416 GYPRSHILTEEERQDK-IVVHLGLSGEANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIF 474
PR L+ + K I V+ GL G++ A K + I ID Y+R +F
Sbjct: 425 SLPRDFELSNYDCYGKPIEVNNGL-GKSQAKNNKKPPPAKP--VIPTAAKRIDLYARALF 481
Query: 475 PASYIFFNLIYWSVF 489
P ++FFN+IYWS++
Sbjct: 482 PFCFLFFNVIYWSIY 496
>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
[Homo sapiens]
Length = 467
Score = 238 bits (608), Expect = 7e-63
Identities = 154/478 (32%), Positives = 244/478 (51%), Gaps = 45/478 (9%)
Query: 33 ILFLFCLMVLVESRKPK-----------RKRWTGQVEMPKPSHLYKKNLDVTKIRKGKPQ 81
+L L CL + +R K ++W V PK ++ DVT I
Sbjct: 5 LLLLLCLFSGLHARSRKVEEDEYEDSSSNQKW---VLAPK-----SQDTDVTLILN---- 52
Query: 82 QLLRVDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFS 141
+LLR E+D +RP G + VD+ V S+ +S ++M++ + ++ W D RL F+
Sbjct: 53 KLLR--EYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFN 110
Query: 142 SASNKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTA 201
S K +T + +V IW+PD F +SK + H TT N +LR++ DG +LY++R+T+ A
Sbjct: 111 STM-KILTLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINA 169
Query: 202 MCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTT 261
C + +FP+D +C L SY Y E+++ W+ + L QF T
Sbjct: 170 ECQLQLHNFPMDEHSCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNT 229
Query: 262 SRLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSL 321
+ + +S G Y + I F L R + +F +QTY P L V+LSWVSFWI + A PAR +L
Sbjct: 230 TEIVT-TSAGDYVVMTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTAL 288
Query: 322 GITTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKE 381
GITTVLTMTT+ T S+PRVSYV A+D+++ V F+FVF +++EYA +NY ++ ++
Sbjct: 289 GITTVLTMTTLSTIARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTT 348
Query: 382 RKLREKF--PCMCGMLHSK-TMMLDGSYS--ESEANSLAGYPRSHILTEEERQDKIVVHL 436
K P + + ++ +YS + A ++ + +E +D V
Sbjct: 349 TKKTTSLLHPDSSRWIPERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYEC 408
Query: 437 GLSGE--------ANAARKKGLLKGQTGFRIFQNTHAIDKYSRLIFPASYIFFNLIYW 486
L G+ + KG+ I + +D YSR+ FP S++ FNL+YW
Sbjct: 409 -LDGKDCQSFFCCYEECKSGSWRKGRIHIDILE----LDSYSRVFFPTSFLLFNLVYW 461
>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
[Homo sapiens]
Length = 554
Score = 234 bits (597), Expect = 1e-61
Identities = 121/307 (39%), Positives = 182/307 (59%), Gaps = 6/307 (1%)
Query: 86 VDEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSSASN 145
+D +D +RP FGGP V D+ V S +S+V+M++TM ++ R W D+RL +
Sbjct: 56 LDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPI- 114
Query: 146 KSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNM 205
+ + + +V K+W PD FF + K+S +H+ T N + R+ +G +LY+MR+T++A C M
Sbjct: 115 EILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPM 174
Query: 206 DFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKF---HTTS 262
FP+D C L+ SYAY +++ W G E K+ E S L+Q T S
Sbjct: 175 RLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPE--KSVEVPKESSSLVQYDLIGQTVS 232
Query: 263 RLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLG 322
S TG Y + + F LRR + +F++QTY P + V+LS VSFWI++ +VPAR G
Sbjct: 233 SETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFG 292
Query: 323 ITTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKER 382
ITTVLTMTT+ S+P+VSY A+D ++ V F FVF +++E+AAVNY T +Q K +
Sbjct: 293 ITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQMEKAK 352
Query: 383 KLREKFP 389
+ K P
Sbjct: 353 RKTSKPP 359
Score = 37.7 bits (86), Expect = 0.024
Identities = 13/27 (48%), Positives = 21/27 (77%)
Query: 463 THAIDKYSRLIFPASYIFFNLIYWSVF 489
T IDKY+R++FP ++ FN++YW V+
Sbjct: 515 TSKIDKYARILFPVTFGAFNMVYWVVY 541
>gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon
precursor [Homo sapiens]
Length = 506
Score = 233 bits (595), Expect = 2e-61
Identities = 140/447 (31%), Positives = 232/447 (51%), Gaps = 36/447 (8%)
Query: 73 TKIRKGKPQQLLRV-----DEHDFSMRPAFGGPAIPVGVDVQVESLDSISEVDMDFTMTL 127
T R GK + R+ +D +RP G V V++ V SL +S +DM++T+ +
Sbjct: 61 TGSRVGKLPEASRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDI 120
Query: 128 YLRHYWKDERLAFSSASNKSMTFDGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFP 187
W DERL ++ +S+ +G +V ++W+PD FF +SKR+ H+ T N M+R++
Sbjct: 121 IFSQTWYDERLCYNDTF-ESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYK 179
Query: 188 DGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEK 247
DG VLY++R+T+ A C++ FP+DS +C L S++Y + +++ W+N L+ +EK
Sbjct: 180 DGKVLYTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENF--KLEINEK 237
Query: 248 ISLSQFLIQKFHTTSRLAFYSS-TGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWV 306
S F +++ ++ G + + I F + R + Q Y P+++ MLSWV
Sbjct: 238 NSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWV 297
Query: 307 SFWIDRRAVPARVSLGITTVLTMTTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLE 366
SFWI + PAR SLGIT+VLTMTT+ T + PRVSY+ A+D Y+ + FVF F ++LE
Sbjct: 298 SFWIKTESAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLE 357
Query: 367 YAAVNYLTTVQERKERKLREKFPCMCGMLHSKT-------------------MMLDGSYS 407
+A +N+L Q + + + P + H++T + +GS
Sbjct: 358 FAVLNFLIYNQTKAHASPKLRHPRINSRAHARTRARSRACARQHQEAFVCQIVTTEGSDG 417
Query: 408 ESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAARKKGLL----KGQT--GFRIFQ 461
E + A P S E R + L +K + +G T R+
Sbjct: 418 EERPSCSAQQPPSPGSPEGPR--SLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCI 475
Query: 462 NTHAIDKYSRLIFPASYIFFNLIYWSV 488
+ + +D YSR++FP ++ FFN++YW V
Sbjct: 476 HVYRLDNYSRVVFPVTFFFFNVLYWLV 502
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.137 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,443,933
Number of Sequences: 37866
Number of extensions: 727716
Number of successful extensions: 2233
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2040
Number of HSP's gapped (non-prelim): 112
length of query: 490
length of database: 18,247,518
effective HSP length: 106
effective length of query: 384
effective length of database: 14,233,722
effective search space: 5465749248
effective search space used: 5465749248
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.