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Search of human proteins with 151101459
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|151101459 SAPS domain family, member 1 [Homo sapiens]
(881 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|151101459 SAPS domain family, member 1 [Homo sapiens] 1767 0.0
gi|37537701 SAPS domain family, member 2 [Homo sapiens] 652 0.0
gi|13489083 SAPS domain family, member 3 [Homo sapiens] 627 e-179
gi|169218088 PREDICTED: similar to SAPS domain family, member 2 ... 70 7e-12
gi|210032580 SET domain containing 1B [Homo sapiens] 67 7e-11
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 66 2e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni... 64 6e-10
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 61 4e-09
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 61 5e-09
gi|21735415 centromere protein B [Homo sapiens] 59 2e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 58 3e-08
gi|55741677 SET domain containing 1A [Homo sapiens] 57 8e-08
gi|6912492 mitogen-activated protein kinase 8 interacting protei... 57 8e-08
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 57 1e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 57 1e-07
gi|222418647 mucin 7, secreted precursor [Homo sapiens] 56 1e-07
gi|222418649 mucin 7, secreted precursor [Homo sapiens] 56 1e-07
gi|222418645 mucin 7, secreted precursor [Homo sapiens] 56 1e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 56 2e-07
gi|7706537 mitogen-activated protein kinase 8 interacting protei... 56 2e-07
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 55 2e-07
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 55 2e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 55 3e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 8e-07
gi|167736355 mucin 4 isoform a [Homo sapiens] 53 1e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 53 1e-06
gi|116284392 mucin 2 precursor [Homo sapiens] 53 1e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 52 2e-06
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 52 2e-06
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 52 2e-06
>gi|151101459 SAPS domain family, member 1 [Homo sapiens]
Length = 881
Score = 1767 bits (4576), Expect = 0.0
Identities = 881/881 (100%), Positives = 881/881 (100%)
Query: 1 MFWKFDLHTSSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQPPHLQAMVAW 60
MFWKFDLHTSSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQPPHLQAMVAW
Sbjct: 1 MFWKFDLHTSSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQPPHLQAMVAW 60
Query: 61 VTQEPPDSGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSTGSLNPLL 120
VTQEPPDSGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSTGSLNPLL
Sbjct: 61 VTQEPPDSGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSTGSLNPLL 120
Query: 121 ASFFSKVMGILINRKTDQLVSFLRKKDDFVDLLLQHIGTSAIMDLLLRLLTCVERPQLRQ 180
ASFFSKVMGILINRKTDQLVSFLRKKDDFVDLLLQHIGTSAIMDLLLRLLTCVERPQLRQ
Sbjct: 121 ASFFSKVMGILINRKTDQLVSFLRKKDDFVDLLLQHIGTSAIMDLLLRLLTCVERPQLRQ 180
Query: 181 DVVNWLNEEKIVQRLIEQIHPSKDENQHSNASQSLCDIIRLSREQMIQVQDSPEPDQLLA 240
DVVNWLNEEKIVQRLIEQIHPSKDENQHSNASQSLCDIIRLSREQMIQVQDSPEPDQLLA
Sbjct: 181 DVVNWLNEEKIVQRLIEQIHPSKDENQHSNASQSLCDIIRLSREQMIQVQDSPEPDQLLA 240
Query: 241 TLEKQETIEQLLSNMFEGEQSQSVIVSGIQVLLTLLEPRRPRSESVTVNSFFSSVDGQLE 300
TLEKQETIEQLLSNMFEGEQSQSVIVSGIQVLLTLLEPRRPRSESVTVNSFFSSVDGQLE
Sbjct: 241 TLEKQETIEQLLSNMFEGEQSQSVIVSGIQVLLTLLEPRRPRSESVTVNSFFSSVDGQLE 300
Query: 301 LLAQGALESTVSSVGALHALRPRLSCFHQLLLEPPKLEPLQMTWGMLAPPLGNTRLHVVK 360
LLAQGALESTVSSVGALHALRPRLSCFHQLLLEPPKLEPLQMTWGMLAPPLGNTRLHVVK
Sbjct: 301 LLAQGALESTVSSVGALHALRPRLSCFHQLLLEPPKLEPLQMTWGMLAPPLGNTRLHVVK 360
Query: 361 LLASALSANDAALTHELLALDVPNTMLDLFFHYVFNNFLHAQVEGCVSTMLSLGPPPDSS 420
LLASALSANDAALTHELLALDVPNTMLDLFFHYVFNNFLHAQVEGCVSTMLSLGPPPDSS
Sbjct: 361 LLASALSANDAALTHELLALDVPNTMLDLFFHYVFNNFLHAQVEGCVSTMLSLGPPPDSS 420
Query: 421 PETPIQNPVVKHLLQQCRLVERILTSWEENDRVQCAGGPRKGYMGHLTRVAGALVQNTEK 480
PETPIQNPVVKHLLQQCRLVERILTSWEENDRVQCAGGPRKGYMGHLTRVAGALVQNTEK
Sbjct: 421 PETPIQNPVVKHLLQQCRLVERILTSWEENDRVQCAGGPRKGYMGHLTRVAGALVQNTEK 480
Query: 481 GPNAEQLRQLLKELPSEQQEQWEAFVSGPLAETNKKNMVDLVNTHHLHSSSDDEDDRLKE 540
GPNAEQLRQLLKELPSEQQEQWEAFVSGPLAETNKKNMVDLVNTHHLHSSSDDEDDRLKE
Sbjct: 481 GPNAEQLRQLLKELPSEQQEQWEAFVSGPLAETNKKNMVDLVNTHHLHSSSDDEDDRLKE 540
Query: 541 FNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTANITFSLNAD 600
FNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTANITFSLNAD
Sbjct: 541 FNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTANITFSLNAD 600
Query: 601 DENPNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPP 660
DENPNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPP
Sbjct: 601 DENPNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPP 660
Query: 661 GVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVP 720
GVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVP
Sbjct: 661 GVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVP 720
Query: 721 TDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQ 780
TDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQ
Sbjct: 721 TDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQ 780
Query: 781 EATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQT 840
EATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQT
Sbjct: 781 EATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQT 840
Query: 841 TEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPGSQ 881
TEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPGSQ
Sbjct: 841 TEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPGSQ 881
>gi|37537701 SAPS domain family, member 2 [Homo sapiens]
Length = 932
Score = 652 bits (1682), Expect = 0.0
Identities = 385/930 (41%), Positives = 531/930 (57%), Gaps = 120/930 (12%)
Query: 1 MFWKFDLHTSSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQPPHLQAMVAW 60
MFWKFDL+T+SH+D LL++E ++L EL+DE+D+LQECK N+KLLDFL + ++ +V+
Sbjct: 1 MFWKFDLNTTSHVDKLLDKEHVTLQELMDEDDILQECKAQNQKLLDFLCRQQCMEELVSL 60
Query: 61 VTQEPPDSGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSTGSLNPLL 120
+TQ+PP EE++R+KYP+ ACE+LT DVPQI+D LG DESLL+ LY FL LNPLL
Sbjct: 61 ITQDPPLDMEEKVRFKYPNTACELLTCDVPQISDRLGGDESLLSLLYDFLDHEPPLNPLL 120
Query: 121 ASFFSKVMGILINRKTDQLVSFLRKKDDFVDLLLQHIGTSAIMDLLLRLLTCVERPQLRQ 180
ASFFSK +G LI RKT+Q+++FL+KKD F+ L+L+HIGTSA+MDLLLRL++CVE LRQ
Sbjct: 121 ASFFSKTIGNLIARKTEQVITFLKKKDKFISLVLKHIGTSALMDLLLRLVSCVEPAGLRQ 180
Query: 181 DVVNWLNEEKIVQRLIEQIHPSKDENQHSNASQSLCDIIRLSREQMIQVQDSPEPDQLLA 240
DV++WLNEEK++QRL+E IHPS+DE++ SNASQ+LCDI+RL R+Q Q+Q++ EPD LL
Sbjct: 181 DVLHWLNEEKVIQRLVELIHPSQDEDRQSNASQTLCDIVRLGRDQGSQLQEALEPDPLLT 240
Query: 241 TLEKQETIEQLLSNMFEGEQSQSVIVSGIQVLLTLLEPRRPRSESVTVNSFFSSVDGQLE 300
LE Q+ +EQLL NMF+G++++S +VSG QVLLTLLE RR +E G ++
Sbjct: 241 ALESQDCVEQLLKNMFDGDRTESCLVSGTQVLLTLLETRRVGTE------------GLVD 288
Query: 301 LLAQGALESTVSSVGALHALRPRLSCFHQLLLEPPKLEPLQMTWGMLAPPLGNTRLHVVK 360
+QG S S LH + PRL FHQLLL PPK + + T G+L PLGN RLH +
Sbjct: 289 SFSQGLERSYAVSSSVLHGIEPRLKDFHQLLLNPPKKKAILTTIGVLEEPLGNARLHGAR 348
Query: 361 LLASALSANDAALTHELLALDVPNTMLDLFFHYVFNNFLHAQVEGCVSTMLS-------- 412
L+A+ L N ++ EL L+ + +LDLFF Y +NNFLH QVE C++ +LS
Sbjct: 349 LMAALLHTNTPSINQELCRLNTMDLLLDLFFKYTWNNFLHFQVELCIAAILSHAAREERT 408
Query: 413 --------LGPPPDS---SPETP------IQNPVVKHLLQQCRLVERILTSWEENDRVQC 455
+ PP ++ S ETP N +V HL Q+C LV+RIL +WE ND Q
Sbjct: 409 EASGSESRVEPPHENGNRSLETPQPAASLPDNTMVTHLFQKCCLVQRILEAWEANDHTQA 468
Query: 456 AGGPRKGYMGHLTRVAGALVQNTEKGPNAEQLRQLLKELPSEQQEQWEAFVSGPLAETNK 515
AGG R+G MGHLTR+A A+VQN E+GP + ++++ LP++ + +WE+FV L ETN+
Sbjct: 469 AGGMRRGNMGHLTRIANAVVQNLERGPVQTHISEVIRGLPADCRGRWESFVEETLTETNR 528
Query: 516 KNMVDLVNTHHLHSSSDDEDDRLKEFNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEE 575
+N VDL AF D+Q+Q+MT+ F+D FGFNDEE
Sbjct: 529 RNTVDL------------------------------AFSDYQIQQMTANFVDQFGFNDEE 558
Query: 576 FGEQEESVNAPFDKTANITFSLNADDENPNANLLEICYKDRIQQFDDDEEEEDEEEAQGS 635
F +Q++++NAPFD+ A I F+++AD+++P+A L E C DRIQ FDDDE+E+
Sbjct: 559 FADQDDNINAPFDRIAEINFNIDADEDSPSAALFEACCSDRIQPFDDDEDED-------- 610
Query: 636 GESDGEDGAWQGSQLARGARLGQPP--GVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARG 693
W+ S AR+ P G + S++ E ++ + A G
Sbjct: 611 --------IWEDSDTRCAARVMARPRFGAPHASESCSKNGPERGGQDGKASLEAHRDAPG 662
Query: 694 GATPLSYPSPGPQ--PP------GPSWTATFDPVPTDAPTSP---RVSGEEELHTGPPAP 742
P P+PG + PP G WTA FD PT+P R G G AP
Sbjct: 663 AGAP---PAPGKKEAPPVEGDSEGAMWTAVFDEPANSTPTAPGVVRDVGSSVWAAGTSAP 719
Query: 743 Q----------GPLSVPQGLP-TQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEP 791
+ P + P S A RSQ P +P +
Sbjct: 720 EEKGWAKFTDFQPFCCSESGPRCSSPVDTECSHAEGSRSQGPEKAFSPASPCAWNVCVTR 779
Query: 792 SAPCQALVSIGDLQATFH---GIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPE 848
AP L S H G + A S+ D+ +R P P P E++
Sbjct: 780 KAP--LLASDSSSSGGSHSEDGDQKAASAMDAVSRGPGREAPPL-----PTVARTEEAVG 832
Query: 849 PLGLPQSQSAQALTPPPIPNGSAPEGPASP 878
+G S+ P P +AP P
Sbjct: 833 RVGCADSRLLSPACPAPKEVTAAPAVAVPP 862
>gi|13489083 SAPS domain family, member 3 [Homo sapiens]
Length = 793
Score = 627 bits (1618), Expect = e-179
Identities = 380/914 (41%), Positives = 513/914 (56%), Gaps = 161/914 (17%)
Query: 1 MFWKFDLHTSSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQPPHLQAMVAW 60
MFWKFDLH+SSH+DTLLERED++L EL+DEEDVLQECK NRKL++FLL+ L+ +V++
Sbjct: 1 MFWKFDLHSSSHIDTLLEREDVTLKELMDEEDVLQECKAQNRKLIEFLLKAECLEDLVSF 60
Query: 61 VTQEPPDSGEERLRYKYPSVACEILTSDVPQINDALGADESLLNRLYGFLQSTGSLNPLL 120
+ +EPP +E++RYKYP+++CE+LTSDV Q+ND LG DESLL +LY FL + LNPLL
Sbjct: 61 IIEEPPQDMDEKIRYKYPNISCELLTSDVSQMNDRLGEDESLLMKLYSFLLNDSPLNPLL 120
Query: 121 ASFFSKVMGILINRKTDQLVSFLRKKDDFVDLLLQHIGTSAIMDLLLRLLTCVERPQLRQ 180
ASFFSKV+ ILI+RK +Q+V FL+KK DFVDL+++HIGTSAIMDLLLRLLTC+E PQ RQ
Sbjct: 121 ASFFSKVLSILISRKPEQIVDFLKKKHDFVDLIIKHIGTSAIMDLLLRLLTCIEPPQPRQ 180
Query: 181 DVVNWLNEEKIVQRLIEQIHPSKDENQHSNASQSLCDIIRLSREQMIQVQDSPEPDQLLA 240
DV+NWLNEEKI+QRL+E +HPS++E++HSNASQSLC+I+RLSR+QM+Q+Q+S EPD LLA
Sbjct: 181 DVLNWLNEEKIIQRLVEIVHPSQEEDRHSNASQSLCEIVRLSRDQMLQIQNSTEPDPLLA 240
Query: 241 TLEKQETIEQLLSNMFEGEQSQSVIVSGIQVLLTLLEPRRPRSESVTVNSFFSSVDGQLE 300
TLEKQE IEQLLSN+F E+++S IVS IQ+LLTLLE RRP + +G +E
Sbjct: 241 TLEKQEIIEQLLSNIFHKEKNESAIVSAIQILLTLLETRRP------------TFEGHIE 288
Query: 301 LLAQGALESTVS-SVGALHALRPRLSCFHQLLLEPPKLEPLQMTWGMLAPPLGNTRLHVV 359
+ G S S + L A+R RL FH+LLLEPPK + TW
Sbjct: 289 ICPPGMSHSACSVNKSVLEAIRGRLGSFHELLLEPPKNMFFKYTW--------------- 333
Query: 360 KLLASALSANDAALTHELLALDVPNTMLDLFFHYVFNNFLHAQVEGCVSTMLSLGPPPDS 419
NNFLH QVE C++ L L P ++
Sbjct: 334 ------------------------------------NNFLHTQVEICIA--LILASPFEN 355
Query: 420 SPETPI-------QNPVVKHLLQQCRLVERILTSWEENDRVQCAGGPRKGYMGHLTRVAG 472
+ I N ++KHL Q+C+L+ERIL +WE N++ Q GG R GYMGHLTR+A
Sbjct: 356 TENATITDQDSTGDNLLLKHLFQKCQLIERILEAWEMNEKKQAEGGRRHGYMGHLTRIAN 415
Query: 473 ALVQNTEKGPNAEQLRQLLKELPSEQQEQWEAFVSGPLAETNKKNMVDLVNTHHLHSSSD 532
+V +T+KGPN+ ++QL+K+LP E +E+WE F + L ETNK+N VDL
Sbjct: 416 CIVHSTDKGPNSALVQQLIKDLPDEVRERWETFCTSSLGETNKRNTVDL----------- 464
Query: 533 DEDDRLKEFNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTAN 592
AF D+QMQ+MTS FID FGFNDE+F +Q++ N FD+ ++
Sbjct: 465 -------------------AFSDYQMQQMTSNFIDQFGFNDEKFADQDDIGNVSFDRVSD 505
Query: 593 ITFSLNADDENPNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLAR 652
I F+LN +E+ N L E C K+RIQQFDD G SD ED W+ +A
Sbjct: 506 INFTLNT-NESGNIALFEACCKERIQQFDD-------------GGSDEED-IWEEKHIA- 549
Query: 653 GARLGQPPGVR--SGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGP 710
P R S GSTDSE+ + +EE+ ++ ++ + P P
Sbjct: 550 ----FTPESQRRSSSGSTDSEESTDSEEEDGAKQDLFEPSSANTEDKMEVDLSEP----P 601
Query: 711 SWTATFD-------PVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQS--LASPP 761
+W+A FD P D+ S S EE + T L T+ ++ P
Sbjct: 602 NWSANFDVPMETTHGAPLDSVGSDVWSTEEPMPTKETGWASFSEFTSSLSTKDSLRSNSP 661
Query: 762 ARDALQLRSQDPTPPSAP--------------QEATEGSKVTEPSAPCQALVSIGDLQAT 807
DP PSA + +++G + E + V G ++ T
Sbjct: 662 VEMETSTEPMDPLTPSAAALAVQPEAAGSVAMEASSDGEEDAESTDKVTETVMNGGMKET 721
Query: 808 FH-----GIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGE-KSPEPLGLPQSQSAQAL 861
+A S+ S A + P+T E + +P P P S Q
Sbjct: 722 LSLTVDAKTETAVFKSEEGKLSTSQDAACKDAEECPETAEAKCAAPRP---PSSSPEQRT 778
Query: 862 TPPPIPNGSAPEGP 875
P P ++ GP
Sbjct: 779 GQPSAPGDTSVNGP 792
>gi|169218088 PREDICTED: similar to SAPS domain family, member 2
[Homo sapiens]
Length = 79
Score = 70.5 bits (171), Expect = 7e-12
Identities = 31/44 (70%), Positives = 40/44 (90%)
Query: 163 MDLLLRLLTCVERPQLRQDVVNWLNEEKIVQRLIEQIHPSKDEN 206
MDLLLRL++CVE LRQDV++WLNEEK++QRL+E IHPS+DE+
Sbjct: 1 MDLLLRLVSCVEPAGLRQDVLHWLNEEKVIQRLVELIHPSQDED 44
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 67.0 bits (162), Expect = 7e-11
Identities = 95/362 (26%), Positives = 136/362 (37%), Gaps = 57/362 (15%)
Query: 532 DDEDDRLKEFNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTA 591
DD DDR + N E+ L +A + + E E S ++ F+ ++
Sbjct: 1066 DDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSS 1125
Query: 592 NITFSLNADDENPNANLLEICYKDRIQQFDDDEEEEDEEEAQGSG-----ESDGEDGAWQ 646
+ S + D+E A R ++ +++EEE EE+ S E DGE+ A
Sbjct: 1126 ESSPSSSEDEEEVVA---------REEEEEEEEEEMVAEESMASAGPEDFEQDGEEAA-- 1174
Query: 647 GSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEEEE-----DEEGIGCAARGGATPLSYP 701
LA GA P V S G + D E E EE DE + A P
Sbjct: 1175 ---LAPGA-----PAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPP 1226
Query: 702 -SPGPQPPGPSWTATFDP---VPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSL 757
PG G + P V P SP + E +L P+ P+ +P LP Q
Sbjct: 1227 EEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEV---EPEPPMMLP--LPLQPP 1281
Query: 758 ASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSS 817
PP + P PPS P E E + + PS P + L A H +
Sbjct: 1282 LPPP---------RPPRPPSPPPE-PETTDASHPSVPPEPL-------AEDHPPHTPGLC 1324
Query: 818 SDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPAS 877
A + +VPA+ +PP G S L PQ + P P P+ S+ P +
Sbjct: 1325 GSLAKSQSTETVPATPGGEPP--LSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRT 1382
Query: 878 PG 879
PG
Sbjct: 1383 PG 1384
Score = 47.8 bits (112), Expect = 5e-05
Identities = 76/330 (23%), Positives = 116/330 (35%), Gaps = 82/330 (24%)
Query: 621 DDDEEEEDEEEAQGSGESDGED----------------------------------GAWQ 646
+++EE E+EEE + + D +D +
Sbjct: 1049 EEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAE 1108
Query: 647 GSQLARGARLGQPPGVRSGGSTDSEDEEE----EDEEEEEDEEGIGCAARGGATPLSYPS 702
+ + + + + SEDEEE E+EEEEE+EE + + A P +
Sbjct: 1109 ATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQ 1168
Query: 703 PGPQ----PPGPSWTATFDPVPTDAPTS-------PRVSGEEELHTGPPAPQGPLSVPQ- 750
G + P P+ + D T P + E L G P P+
Sbjct: 1169 DGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEE 1228
Query: 751 -GLPTQSL----ASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQ 805
GL + PPA++ + PP +P+ A E EP P + LQ
Sbjct: 1229 PGLSQEGAMLLSPEPPAKEV------EARPPLSPERAPEHDLEVEPEPPMMLPL---PLQ 1279
Query: 806 ATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLG----LPQSQSAQAL 861
R P S +P T+ AS PP+ + P G L +SQS + +
Sbjct: 1280 PPLPPPR--PPRPPSPPPEPETT-DASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETV 1336
Query: 862 --TP---PPIPNG------SAPEGPASPGS 880
TP PP+ G S+P+ P SP S
Sbjct: 1337 PATPGGEPPLSGGSSGLSLSSPQVPGSPFS 1366
Score = 40.0 bits (92), Expect = 0.010
Identities = 53/186 (28%), Positives = 69/186 (37%), Gaps = 31/186 (16%)
Query: 704 GPQPPG--PSWTATFDPVPTDAPTSPRVSGEEELHTG----PPAPQGPLSVPQGLPTQSL 757
GP PP PS T D PT P S +EEL G PP GP P GL +Q+
Sbjct: 556 GPTPPSSRPSSTGLEDISPTPLPDSDE---DEELDLGLGPRPPPEPGPPD-PAGLLSQT- 610
Query: 758 ASPPARDALQLRSQDPTPPS-----APQEATEGSKVTEPSAPCQALVSIGDLQATFHGIR 812
A AL L D TP S Q + E ++++ P + S D
Sbjct: 611 ----AEVALDLVG-DRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITS-ADCPKPMVVTP 664
Query: 813 SAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAP 872
A + + + P+ +P P P+P G P PPP+P P
Sbjct: 665 GAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQP-GFPM--------PPPLPPPPPP 715
Query: 873 EGPASP 878
PA P
Sbjct: 716 PPPAHP 721
Score = 37.7 bits (86), Expect = 0.047
Identities = 69/275 (25%), Positives = 93/275 (33%), Gaps = 65/275 (23%)
Query: 576 FGEQEESVNAPFDKTANITFSLNADDENPNANL---LEICYKDR------IQQFDDDEEE 626
FG E ++P T S A E P+ +L +E+ K++ +++ D D E
Sbjct: 470 FGWSPEPCDSPGTPTLE---SSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTEL 526
Query: 627 EDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGSTDSEDEEE----EDEEEEE 682
+ E S S A G+ G R PP R ST ED + +E+EE
Sbjct: 527 QMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPS-STGLEDISPTPLPDSDEDEE 585
Query: 683 DEEGIGCAARGGATPLSYPSPGPQPPGPSWTAT----FDPVPTDAPTSPRV------SGE 732
+ G+G P P PGP P + T D V PTS ++ SGE
Sbjct: 586 LDLGLG--------PRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGE 637
Query: 733 E------ELHTGPP------------------------APQGPLSVPQGLPTQSLASPPA 762
+ E+ + P AP PL P G P PP
Sbjct: 638 DMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPP 697
Query: 763 RDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQA 797
P PP P VT P P A
Sbjct: 698 PPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPA 732
Score = 36.2 bits (82), Expect = 0.14
Identities = 55/231 (23%), Positives = 80/231 (34%), Gaps = 53/231 (22%)
Query: 695 ATPLSYPSPGPQPPGPSWTATFDPV---------PTDAPTS-----PRVSGEEELHTGPP 740
AT P P P P + + F P P + PT+ R SGE PP
Sbjct: 376 ATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPP 435
Query: 741 --APQGPLS-----VPQGLPTQSLASPPARDALQLRSQ-----DPTPPSAPQEATEGSKV 788
P PL+ P G P PP ++++L + P P +P T S
Sbjct: 436 PLPPAEPLAKEKPGTPPGPP------PPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSP 489
Query: 789 TEPSAPCQALVSIGDL----QATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGE 844
P P +L S ++ Q T P SD+ + + + +S + P G
Sbjct: 490 AGPEKPHDSLDSRIEMLLKEQRTKLLFLREP-DSDTELQMEGSPISSSSSQLSPLAPFGT 548
Query: 845 KS-------PEPLGLPQSQSAQALTPPPIPN---------GSAPEGPASPG 879
S P P S + ++P P+P+ G P P PG
Sbjct: 549 NSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPG 599
Score = 33.5 bits (75), Expect = 0.89
Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 13/78 (16%)
Query: 621 DDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGG-------------S 667
D+++EE + E + ++ E + R +P + SGG S
Sbjct: 988 DEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQES 1047
Query: 668 TDSEDEEEEDEEEEEDEE 685
T+ E+E EE+EEEE+D++
Sbjct: 1048 TEEEEEAEEEEEEEDDDD 1065
Score = 31.6 bits (70), Expect = 3.4
Identities = 31/103 (30%), Positives = 39/103 (37%), Gaps = 28/103 (27%)
Query: 631 EAQGSGESDGEDGAWQGSQLARGARLG-------QPPGVRSGG---------STDSEDEE 674
E+ G GE G +G G L RL +PP S G S D EDEE
Sbjct: 934 ESWGKGEGLGYEGLGLGIGLRGAIRLPSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEE 993
Query: 675 EEDEEEEE-----------DEEGIGCAARGGATPLSYPSPGPQ 706
E E + + D +G+G R A PL S G +
Sbjct: 994 SERERDRDMADTPCELAKRDPKGVG-VRRRPARPLELDSGGEE 1035
Score = 31.2 bits (69), Expect = 4.4
Identities = 21/67 (31%), Positives = 25/67 (37%), Gaps = 8/67 (11%)
Query: 694 GATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLP 753
G PL P P P PP P + P+P P P H P PL P G+P
Sbjct: 686 GFPPLP-PPPPPPPPQPGFPMP-PPLPPPPPPPPPA------HPAVTVPPPPLPAPPGVP 737
Query: 754 TQSLASP 760
+ P
Sbjct: 738 PPPILPP 744
Score = 31.2 bits (69), Expect = 4.4
Identities = 26/116 (22%), Positives = 42/116 (36%), Gaps = 9/116 (7%)
Query: 692 RGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTS---PRVSGEEELHTGPPAPQGPLSV 748
R P P PQPP P P P PT + + PP P+G V
Sbjct: 1532 RNAGIPAPPPPLPPQPPPPP------PPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEV 1585
Query: 749 PQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDL 804
+ + + P R + R +D PP+ E + + P + + + + D+
Sbjct: 1586 TEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTILYDI 1641
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 65.9 bits (159), Expect = 2e-10
Identities = 74/276 (26%), Positives = 108/276 (39%), Gaps = 44/276 (15%)
Query: 630 EEAQGSGESDGEDGAWQGSQLAR-GARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIG 688
E QG G+ + +WQ R G+ G P + ++EEE+ EEEE+D+EG
Sbjct: 324 ESGQGQGQ---HEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEE 380
Query: 689 CAARGGAT----------------PLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSG- 731
R A PL+ P+P P PP P +T P P P P VS
Sbjct: 381 KEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPP-PSTSPPPPLCPPPPPPVSPP 439
Query: 732 -----------EEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPS-AP 779
EE+ + PP S +G P + + R+A + + +PP+ P
Sbjct: 440 PLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP 499
Query: 780 QEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSAT------RDPST--SVPA 831
AT G P+ ++ + +++ + SA SS T DP V
Sbjct: 500 STATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEV 559
Query: 832 SGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIP 867
S +PP TT EP +P +A TPP P
Sbjct: 560 SPVLRPPITTSPPVPQEPAPVP--SPPRAPTPPSTP 593
Score = 41.6 bits (96), Expect = 0.003
Identities = 80/351 (22%), Positives = 111/351 (31%), Gaps = 104/351 (29%)
Query: 612 CYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARG----ARLGQPPGVRSGGS 667
C+K + Q+ DD+EEE+ EEE + + E+ A + A+L PP S
Sbjct: 353 CWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS 412
Query: 668 TDSE-------------------------------DEEEEDEEEEEDEEGIGCAARGGAT 696
+EE EE C+ + G
Sbjct: 413 PPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRP 472
Query: 697 PLSYPSP------------GPQPPGPSWTATFDPVPTDAPT----------------SPR 728
PL+ PS G PP P+ + P D+PT P
Sbjct: 473 PLT-PSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPV 531
Query: 729 VSGEEE---------LHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAP 779
VS + PP P + V L SPP Q + P+PP AP
Sbjct: 532 VSARSSRVIKTPRRFMDEDPPKPP-KVEVSPVLRPPITTSPPVP---QEPAPVPSPPRAP 587
Query: 780 QEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRD----PSTSVPASGAH 835
T PS P V + + + + +R S TR+ P P
Sbjct: 588 ---------TPPSTP----VPLPEKRRSI--LREPTFRWTSLTRELPPPPPAPPPPPAPS 632
Query: 836 QPPQTTEGEKSPEPLGLPQSQSAQA--------LTPPPIPNGSAPEGPASP 878
PP + P L PQ ++A LTPPP+ APE P
Sbjct: 633 PPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPP 683
Score = 37.7 bits (86), Expect = 0.047
Identities = 47/182 (25%), Positives = 67/182 (36%), Gaps = 39/182 (21%)
Query: 697 PLSYPSPGPQPPGPSWTATFDPV----PTDAPTSPRVSGEEELHTGPP--APQGPLSVPQ 750
P P P P PP T++ P+ P P+ + E + T PP AP+ P P
Sbjct: 623 PAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP- 681
Query: 751 GLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHG 810
PPA D+ P+ P+ G + S P A V ++A
Sbjct: 682 ---------PPADDS----------PAEPEPRAVG-RTNHLSLPRFAPVVTTPVKA---- 717
Query: 811 IRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGS 870
+P + + + P T QP Q + + P+ L PQ Q L PPP P
Sbjct: 718 -EVSPHGAPALSNGPQTQAQLL---QPLQALQTQLLPQALPPPQPQ----LQPPPSPQQM 769
Query: 871 AP 872
P
Sbjct: 770 PP 771
Score = 37.0 bits (84), Expect = 0.081
Identities = 39/152 (25%), Positives = 53/152 (34%), Gaps = 17/152 (11%)
Query: 705 PQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLP--TQSLASPPA 762
P+PP + P T TSP V E PP P S P LP +S+ P
Sbjct: 552 PKPPKVEVSPVLRPPIT---TSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPT 608
Query: 763 RDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSS---- 818
L + P PP AP S P+ + + + Q T PS +
Sbjct: 609 FRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFT-------PSEAHLKI 661
Query: 819 -DSATRDPSTSVPASGAHQPPQTTEGEKSPEP 849
+S P P + +PP + PEP
Sbjct: 662 YESVLTPPPLGAPEAPEPEPPPADDSPAEPEP 693
Score = 35.8 bits (81), Expect = 0.18
Identities = 47/190 (24%), Positives = 62/190 (32%), Gaps = 56/190 (29%)
Query: 645 WQGSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGI----------------- 687
W G ++ RG G+ G E+E + E +EE+ +G
Sbjct: 84 WAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSSLRSALRS 143
Query: 688 --GCAARG-GATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEE----------E 734
G A RG G + P P P+ D PT T R GEE E
Sbjct: 144 QRGRAPRGRGRKHKTTPLPPPR--------LADVAPTPPKTPARKRGEEGTERMVQALTE 195
Query: 735 LHTGPPAPQGPLS--VPQGLPTQSLASPPARD----------------ALQLRSQDPTPP 776
L APQ P S P +S PP R A+ + +P PP
Sbjct: 196 LLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPP 255
Query: 777 SAPQEATEGS 786
P + GS
Sbjct: 256 VVPVKHQTGS 265
Score = 34.3 bits (77), Expect = 0.52
Identities = 55/211 (26%), Positives = 73/211 (34%), Gaps = 57/211 (27%)
Query: 701 PSPGPQPP-GPSWTATFDPVPTDA------PTSPRVSGEEELHTGPPAPQGP-------- 745
P+P P PP P+ +T P+P PT S EL PPAP P
Sbjct: 577 PAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPA 636
Query: 746 ----------LSVPQGLPTQ-------SLASPPARDALQLRSQDPTPPSAPQEATEGSKV 788
L PQ P++ S+ +PP A + + +P PP A E
Sbjct: 637 PATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPE--APEPEPPPADDSPAE---- 690
Query: 789 TEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSP- 847
EP A + T H S P + T V GA P + G ++
Sbjct: 691 PEPRA----------VGRTNH--LSLPRFAPVVTTPVKAEVSPHGA---PALSNGPQTQA 735
Query: 848 ---EPLGLPQSQSAQALTPPPIPNGSAPEGP 875
+PL Q+Q PPP P P P
Sbjct: 736 QLLQPLQALQTQLLPQALPPPQPQLQPPPSP 766
Score = 31.2 bits (69), Expect = 4.4
Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 16/102 (15%)
Query: 697 PLSYPSPGPQPPGPSWTATFDPVPT----DAPTSPRVSGEEELHTGPPAPQGPLSVPQGL 752
PL S GP P S ++ +PT D P PR S P+P P
Sbjct: 1876 PLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRR-------PSPLAPRP----- 1923
Query: 753 PTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAP 794
P ASPP + + QLR PT T G AP
Sbjct: 1924 PPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAP 1965
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 63.9 bits (154), Expect = 6e-10
Identities = 63/221 (28%), Positives = 84/221 (38%), Gaps = 51/221 (23%)
Query: 688 GCAARGGATP------LSYPSPGPQPPGPSWT------ATFDPVPTDAPTSPRVSGEEEL 735
G ATP L+ PSP P P+ T P P APT+P +
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT----- 1224
Query: 736 HTGPPAPQGPLSVP--QGLPTQSLASPPARD---ALQLRSQDPTPPSAPQEATEGSKVTE 790
PP+P+G L+ P +G PT A+PP+ A PTPP+A + +G T
Sbjct: 1225 ---PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281
Query: 791 P--SAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPE 848
P AP A+V+ PS P P A PP +P
Sbjct: 1282 PHKGAPNPAVVT-------------PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328
Query: 849 PLGLPQSQSAQALTPP--------PIPNGSAPEGPASPGSQ 881
P G P + A+TPP P S+ GP +P S+
Sbjct: 1329 PKGAP---TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366
Score = 60.8 bits (146), Expect = 5e-09
Identities = 56/204 (27%), Positives = 75/204 (36%), Gaps = 32/204 (15%)
Query: 693 GGATPLSYPSPGPQ---PPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLS-- 747
G ATP +P P PP P + P P A T P + PP+P+G +
Sbjct: 999 GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT--------PPSPKGSPAAT 1050
Query: 748 -VPQGLPTQ---SLASPPARDALQLRSQDPTPPSAPQEATEGSKVTE------------P 791
+P+G PT +L SP A PTPP+A + +G T P
Sbjct: 1051 PLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP 1110
Query: 792 SAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLG 851
+P L + A + PS P P + A PP G +P P G
Sbjct: 1111 PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG 1170
Query: 852 LPQSQSAQALTPPPIPNGSAPEGP 875
P + +A TPP G A P
Sbjct: 1171 APTTPAA---TPPSPKGGLATPSP 1191
Score = 57.8 bits (138), Expect = 4e-08
Identities = 61/202 (30%), Positives = 78/202 (38%), Gaps = 32/202 (15%)
Query: 688 GCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTDA-PTSPRVSGEEELHTG-------- 738
G ATP S P GP P P P+P A P SP+ H G
Sbjct: 1078 GAPTPPAATPPS-PKGGPATPSPKGA----PMPPAATPPSPKGGLATPPHKGAPTTPAAT 1132
Query: 739 PPAPQGPLSVP--QGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQ 796
PP+P+G L+ P +G PT A+PP+ + TPP P+ A T PS P
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSP-----KGGLATPP--PKGAPTTPAATPPS-PKG 1184
Query: 797 ALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQ 856
L + A + PS P + A PP G +P P G P +
Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244
Query: 857 SAQALTPPPIPNGSAPEGPASP 878
+A PP P G GPA+P
Sbjct: 1245 AA----TPPSPKG----GPATP 1258
Score = 54.3 bits (129), Expect = 5e-07
Identities = 59/218 (27%), Positives = 90/218 (41%), Gaps = 33/218 (15%)
Query: 685 EGIGCAARGGATP-------------LSYPSPGPQPPG----PSWTATFDPVPTDAPTSP 727
EG ++G TP S P GP P P+ A P P + P
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK 1482
Query: 728 RVSGEEELHTGP--PAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEG 785
+V+ P PAP G ++P +P+ SP A +DP P+A T
Sbjct: 1483 QVATSSSPKKAPATPAPMGAPTLPAVIPS----SPKEVPATPSSRRDPIAPTA----TLL 1534
Query: 786 SKVTEPS-APCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGE 844
SK T + AP +AL+ + + P+ + A PS+ +S P T +G
Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE-APATPSSKEASSPPAVTPSTYKGA 1593
Query: 845 KSPEPLGLPQSQSA----QALTPPPIPNGSAPEGPASP 878
SP+ L +P + ++ +A TPP + S +GPA+P
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATP 1631
Score = 53.1 bits (126), Expect = 1e-06
Identities = 61/218 (27%), Positives = 82/218 (37%), Gaps = 48/218 (22%)
Query: 690 AARGGATPLSYPSPGP-QPPGPSWTATFD--------PVPTDAPTSPRV--SGEEELHTG 738
+++G T + P P +PP P AT P P APT P V S +E+
Sbjct: 1460 SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPAT 1519
Query: 739 PPAPQGPLS---------VPQGLPTQSLASPPARDALQLRSQD--PTPPSAPQEATEGSK 787
P + + P++ P L + PPA + PTP AP AT SK
Sbjct: 1520 PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP--ATPSSK 1577
Query: 788 VTEPSAPCQALVSIGDLQATFHGIRSAPSSSD-----SATRDPSTSVPASGAHQPPQTTE 842
E S+P S T+ G APS + + T P A PP +
Sbjct: 1578 --EASSPPAVTPS------TYKG---APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626
Query: 843 GEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPGS 880
G +P P G P T PP+ S + P SP S
Sbjct: 1627 GPATPAPKGTP--------TSPPVTPSSLKDSPTSPAS 1656
Score = 52.4 bits (124), Expect = 2e-06
Identities = 58/199 (29%), Positives = 71/199 (35%), Gaps = 47/199 (23%)
Query: 688 GCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLS 747
G ATP S P GP P P W T P P SP+ GP P
Sbjct: 938 GAPTPPAATPPS-PKGGPATPSPKWAPT---PPAATPPSPK--------GGPATPS---- 981
Query: 748 VPQGLPTQSLASPPARD---ALQLRSQDPTPPSAPQEATEGSKVTEP-----SAPCQALV 799
P+G PT A+PP+ A PTPP+ + +GS P S P A
Sbjct: 982 -PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
Query: 800 SIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQ 859
+P S +AT P P + A P G +P G P +A
Sbjct: 1041 P-------------SPKGSPAATPLPK-GAPTTPAATLPSPKGGPATPSLKGAPTPPAA- 1085
Query: 860 ALTPPPIPNGSAPEGPASP 878
PP P G GPA+P
Sbjct: 1086 ---TPPSPKG----GPATP 1097
Score = 51.6 bits (122), Expect = 3e-06
Identities = 50/190 (26%), Positives = 69/190 (36%), Gaps = 33/190 (17%)
Query: 698 LSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQG-PLSV-PQGLPTQ 755
L +P GP P P AP S + PAP+G P S P+G PT
Sbjct: 893 LPFPKEGPATPAPK----------QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942
Query: 756 SLASPPARD---ALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIR 812
A+PP+ A PTPP+A + +G T PS G
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT-PSPK---------------GAP 986
Query: 813 SAPSSSDSATRDPSTSVPASGAHQPPQTT--EGEKSPEPLGLPQSQSAQALTPPPIPNGS 870
+ P+++ + + + GA PP T + SP P+ S PP P GS
Sbjct: 987 TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046
Query: 871 APEGPASPGS 880
P G+
Sbjct: 1047 PAATPLPKGA 1056
Score = 48.9 bits (115), Expect = 2e-05
Identities = 58/206 (28%), Positives = 73/206 (35%), Gaps = 31/206 (15%)
Query: 688 GCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTG--------P 739
G ATP S P GP P P T P P S + H G P
Sbjct: 1239 GAPTTPAATPPS-PKGGPATPPPKGAPT---PPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 740 PAPQG--PLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQA 797
P+P+G S P+G PT A+PP+ P +P T P+ +
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPS------------PKGSPGTPPPKGAPTPPAVTPPS 1342
Query: 798 LVSIGDLQAT---FHGIRSAPSSSDSATRDPSTSVPASG-AHQPPQTTEGEKSPEPLGLP 853
L AT G + PSS + T +T G A PP G P P G P
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402
Query: 854 QSQSAQALTPPPIP-NGSAPEGPASP 878
S + L+P P EG A+P
Sbjct: 1403 TSPAVIPLSPKKAPATPVTREGAATP 1428
Score = 47.8 bits (112), Expect = 5e-05
Identities = 58/216 (26%), Positives = 84/216 (38%), Gaps = 22/216 (10%)
Query: 688 GCAARGGATPLSYP-SPGPQPP--GPSWTATFDPVPTDAPTSPRVS----GEEELHTGPP 740
G ATP S SPG PP P+ A P P PT P + G +
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE 1367
Query: 741 APQGPLSVP--QGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQAL 798
P P + P +G P + SP A+ DPT P+ + + + T + A
Sbjct: 1368 GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT 1427
Query: 799 VSIGDL---QATFHGIRSAPSSS--------DSATRDPS-TSVPASGAHQPPQTTEGEKS 846
S GDL T ++ AP++S S+ DP+ +V +PP + S
Sbjct: 1428 PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS 1487
Query: 847 PEPLGLPQSQSAQ-ALTPPPIPNGSAPEGPASPGSQ 881
P P + + A T P + S E PA+P S+
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523
Score = 43.5 bits (101), Expect = 9e-04
Identities = 57/213 (26%), Positives = 76/213 (35%), Gaps = 31/213 (14%)
Query: 696 TPLSYPSPGPQPPGPSWTATFDPVP----TDAPTSPRV------SGEEELHTGPPAPQGP 745
TP S P GP P P T T PV D+PTSP + + G PA +GP
Sbjct: 1620 TPPS-PEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678
Query: 746 ------LSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQ-EATEGSK-VTEPSAPCQA 797
L P T + +P + +S +PP P A GSK AP
Sbjct: 1679 TALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL 1738
Query: 798 LVSIGDLQATFHGIRSAPSSS------DSATRDPSTSVPASGAHQPPQTTEGEKSPE-PL 850
L D T G ++ S +S P T+ P++ +P P+
Sbjct: 1739 LPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPV 1798
Query: 851 GLPQSQSAQALTPP-----PIPNGSAPEGPASP 878
LP + S PP P G E P+ P
Sbjct: 1799 SLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKP 1831
Score = 43.1 bits (100), Expect = 0.001
Identities = 53/196 (27%), Positives = 71/196 (36%), Gaps = 37/196 (18%)
Query: 697 PLSYPSPGPQPPG-PSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQ 755
P S PSP P G P T D + + +P S +E T S +G T
Sbjct: 731 PKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATAS-SKGTLTY 789
Query: 756 SLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAP 815
LA P+ + + Q PP+ A P P IG+L S+P
Sbjct: 790 -LADSPSPLGVSVSPQTKRPPTKKGSAG-------PDTP------IGNL--------SSP 827
Query: 816 SSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTP------------ 863
S A+ P S+ G+ P TT P P G P + L+P
Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT 887
Query: 864 PPIPNGSAP-EGPASP 878
P + N P EGPA+P
Sbjct: 888 PSVVNLPFPKEGPATP 903
Score = 42.0 bits (97), Expect = 0.003
Identities = 52/216 (24%), Positives = 77/216 (35%), Gaps = 33/216 (15%)
Query: 686 GIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTD--APTSPRVSGEEELHTGPPAPQ 743
G+ + + P S GP P + ++ PV S G ++ +P
Sbjct: 798 GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857
Query: 744 GPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEA--TEGSKVTEPS-APCQALVS 800
P P+G PT S +P + + L ++ PS EG P AP ++ S
Sbjct: 858 PPS--PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915
Query: 801 IGDLQATF----HGIRSAPSSSDSATRDPSTS--------------VPASGAHQPPQTTE 842
+A GI ++PS + T +T P A PP
Sbjct: 916 SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975
Query: 843 GEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASP 878
G +P P G P +A PP P G GPA+P
Sbjct: 976 GPATPSPKGAPTPPAA----TPPSPKG----GPATP 1003
Score = 42.0 bits (97), Expect = 0.003
Identities = 54/199 (27%), Positives = 82/199 (41%), Gaps = 43/199 (21%)
Query: 703 PGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPT-QSLASPP 761
P P P T P P +AP +P S +E + PPA S +G P+ + L PP
Sbjct: 1551 PAMTVPSPKKTPAI-PTPKEAPATP--SSKEA--SSPPAVTP--STYKGAPSPKELLIPP 1603
Query: 762 ARDALQLRSQDPTPPS----APQE--ATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAP 815
A + + + PTPP+ +P++ AT K T S P T ++ +P
Sbjct: 1604 AVTSPSPK-EAPTPPAVTPPSPEKGPATPAPKGTPTSPP-----------VTPSSLKDSP 1651
Query: 816 SSSDSATRDPSTSVPASGAHQP----------------PQTTEGEKSPEPLGLPQSQSAQ 859
+S S T +VP + P P++T +P G PQ++ +
Sbjct: 1652 TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG-PQTKKSS 1710
Query: 860 ALTPPPIPNGSAPEGPASP 878
A +PP P+ SA G P
Sbjct: 1711 ATSPPICPDPSAKNGSKGP 1729
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 61.2 bits (147), Expect = 4e-09
Identities = 68/269 (25%), Positives = 104/269 (38%), Gaps = 30/269 (11%)
Query: 628 DEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGI 687
++EE + SG S E+ + ++ + P G SG +T + + E E
Sbjct: 701 EDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAK 760
Query: 688 GCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEE-LHTGPPAPQGPL 746
G P + + GP PPGP T P APT P + E T PPAP P
Sbjct: 761 DTGQNGPKPPATLGADGP-PPGP---PTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPS 816
Query: 747 SVPQGLP-----TQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEP-SAPCQALVS 800
+ P +P ++ A+PP + ++ PP+A + A + K EP + C
Sbjct: 817 APPPVVPKEEKEEETAAAPPVEE-----GEEQKPPAAEELAVDTGKAEEPVKSECTEEAE 871
Query: 801 IGD--------LQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGL 852
G +AT G A + R +T+ +SGA Q ++ + E
Sbjct: 872 EGPAKGKDAEAAEATAEGALKAEKKEGGSGR--ATTAKSSGAPQDSDSSATCSADEVDEA 929
Query: 853 PQSQSAQALTPPP---IPNGSAPEGPASP 878
+ L+P P P G P ASP
Sbjct: 930 EGGDKNRLLSPRPSLLTPTGD-PRANASP 957
Score = 32.0 bits (71), Expect = 2.6
Identities = 71/300 (23%), Positives = 98/300 (32%), Gaps = 68/300 (22%)
Query: 624 EEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEEEED 683
EE+E+E A E E +LA + P V+S + +E EE + +D
Sbjct: 825 EEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEP-VKS----ECTEEAEEGPAKGKD 879
Query: 684 EEGIGCAARG-----------GATPLSYPSPGPQPPGPSWTATFDPVPT------DAPTS 726
E A G G + S PQ S T + D V + S
Sbjct: 880 AEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLS 939
Query: 727 PRVSGEEELHTGPP----APQGPLSVPQ------GLP--TQSLASPPARDALQLRSQDPT 774
PR S TG P +PQ PL + Q +P + PP DA + P
Sbjct: 940 PRPSLLTP--TGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPA 997
Query: 775 PP---------SAPQE------------ATEGSKVTE-----PSAPCQALVSIGDLQATF 808
PP APQ+ A K E P+ +A GD
Sbjct: 998 PPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWT 1057
Query: 809 HGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPN 868
G+ + P P++ ++ PP P PLGL + PP I N
Sbjct: 1058 SGLPFPVPPREVIKASPHAPDPSAFSYAPP------GHPLPLGLHDTARPVLPRPPTISN 1111
Score = 32.0 bits (71), Expect = 2.6
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 824 DPSTSVPASGAHQPPQTTEGEKSP-EPLGLPQSQSAQALTPPPIPNGSAPEGPASPG 879
DP P SG Q + G+ P E LG+P +Q A L + GS P G + G
Sbjct: 1164 DPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTAL--GSVPGGSITKG 1218
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 60.8 bits (146), Expect = 5e-09
Identities = 99/432 (22%), Positives = 156/432 (36%), Gaps = 41/432 (9%)
Query: 480 KGPNAEQLRQLLKELPSEQQEQWEAFVSGPLAETNKKNMVDLVNTHHLHS-SSDDEDDRL 538
+ P AE Q E + +WE AE + T + + ++ ED+
Sbjct: 1875 EAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPE 1934
Query: 539 KEFNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTANITFSLN 598
E +EA ++A + + Q + + +EE + E V A +
Sbjct: 1935 SEGAEAQEA--EEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGE 1992
Query: 599 ADDENPNANLLEICYKDRIQQFDDDEE-EEDEEEAQGSGES------DGEDGAWQGSQLA 651
A E+ + E + +Q+ +++ + E D EAQ E +GE +G
Sbjct: 1993 AQPESEDVEAPEA--EGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQP 2050
Query: 652 RGARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPS 711
+ P + E +E E E E E+ A G A P S P+ G +
Sbjct: 2051 ESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEA 2110
Query: 712 WTATFDPVP-TDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRS 770
A P T+ P G E P A +G+ Q ++ + +
Sbjct: 2111 QKAEGIEAPETEGEAQPESEGIE----APEAEGEAQPESEGVEAQDAEGEAQPESEGIEA 2166
Query: 771 QDPTPPSAPQ----EATEGSKVTEP-SAPCQALVSIGDLQATFHGIRSAPSSSDSATRDP 825
Q+ + P+ EA E +P S +A + G+ Q G+ AP + + A +P
Sbjct: 2167 QEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGV-EAPEAEEEAQPEP 2225
Query: 826 S--TSVPASGAHQPPQ--TTEGEKSPEP---LGLPQSQSAQAL---------TPPPIPNG 869
+ A G QP T+GEK P LG QS+ A TPPP P G
Sbjct: 2226 EGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGG 2285
Query: 870 SAPEGPASPGSQ 881
P PGSQ
Sbjct: 2286 DTPH--QRPGSQ 2295
Score = 44.3 bits (103), Expect = 5e-04
Identities = 52/225 (23%), Positives = 81/225 (36%), Gaps = 12/225 (5%)
Query: 646 QGSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEEEEDE-EGIGCA-ARGGATPLSYPSP 703
QG++ G L Q PGV G + D++ + E EG A R G T S S
Sbjct: 1724 QGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSA 1783
Query: 704 GPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPAR 763
G + + + T + SG E+ G A G Q + + +P A
Sbjct: 1784 GSELGEAEQEG--EGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAE 1841
Query: 764 DALQLRSQDPTPPSAPQEATEGSKVTEP-SAPCQALVSIGDLQATFHGIRSAPSSSDSAT 822
Q S+ P A +A E +P S +A + G+ Q + + + +
Sbjct: 1842 GEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQP 1901
Query: 823 RDPSTSVPASGAHQPPQT-------TEGEKSPEPLGLPQSQSAQA 860
P + P+T TEGE PE G ++ +A
Sbjct: 1902 ESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEA 1946
Score = 41.6 bits (96), Expect = 0.003
Identities = 58/261 (22%), Positives = 89/261 (34%), Gaps = 34/261 (13%)
Query: 631 EAQGSGESDGEDGAWQGSQLARGARLGQP----PGVRSGGSTDSEDEEEEDEEEEEDEEG 686
EA+G + +G S+ + G+ LG+ G+ G T + ED + E G
Sbjct: 1762 EAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAG 1821
Query: 687 IGCAARGGATPLSYPSPGPQPPGPSWTATFDPVP-TDAPTSPRVSGEEELHTGPPAPQGP 745
G Q PG S A P + P G E P +G
Sbjct: 1822 -----------------GDQDPGQSDGAEGIEAPEAEGEAQPESEGVE-----APEAEGD 1859
Query: 746 LSVPQG---LPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTE-PSAPCQALVSI 801
+G ++ + +P A Q S+D P A E S+ E P A +A
Sbjct: 1860 AQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPET 1919
Query: 802 GDLQATFHGIRSAPSSSDSATRDPSTSV-PASGAHQPPQTTEGEKSPEPLGLPQSQSAQA 860
++A P S + ++ + A G QP + E P+S+ +A
Sbjct: 1920 ESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEA 1979
Query: 861 LTPPPIPNGSAPEGPASPGSQ 881
L EG A P S+
Sbjct: 1980 LEVE--VETQEAEGEAQPESE 1998
Score = 40.0 bits (92), Expect = 0.010
Identities = 63/291 (21%), Positives = 101/291 (34%), Gaps = 58/291 (19%)
Query: 624 EEEEDEEEAQGSGESDGED---------------------GAWQGSQLARGARLGQPPGV 662
E E D +EA+G + + ED W+ + GA + P
Sbjct: 1855 EAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGA---EAPEA 1911
Query: 663 RSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTD 722
++E E + E E++ E G A+ A + + G P + +
Sbjct: 1912 EKEAQPETESVEALETEGEDEPESEGAEAQ-EAEEAAQEAEGQTQPESEVIESQEAEEEA 1970
Query: 723 APTSPRVSG-EEELHT----GPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPS 777
P S V E E+ T G P+ ++ + +P A +Q ++ P S
Sbjct: 1971 QPESEDVEALEVEVETQEAEGEAQPE----------SEDVEAPEAEGEMQEAEEEAQPES 2020
Query: 778 APQEA---TEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGA 834
EA +EG + E Q + GD Q G+ AP + + A A G
Sbjct: 2021 DGVEAQPKSEGEEAQEVEGETQK--TEGDAQPESDGV-EAPEAEEEAQEAEGEVQEAEGE 2077
Query: 835 HQP------PQTTEGEKSPEPLGLP------QSQSAQALTPPPIPNGSAPE 873
P Q EGE PE G+ ++Q A+ + P + PE
Sbjct: 2078 AHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPE 2128
Score = 36.6 bits (83), Expect = 0.11
Identities = 57/210 (27%), Positives = 75/210 (35%), Gaps = 36/210 (17%)
Query: 694 GATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHT---GPPAPQGPLSVPQ 750
G +P + PS G S T + P+P S SG L P P PL +
Sbjct: 751 GVSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDSCSKSGAASLGEEARDTPQPSSPLVLQV 810
Query: 751 GLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSK-----------VTEP-SAPC--Q 796
G P Q P SQ T P+ QEA G T P PC +
Sbjct: 811 GRPEQGAVGPHRSHCC---SQPGTQPA--QEAQRGPSPEASWLCGRYCPTPPRGRPCPQR 865
Query: 797 ALVSIGDLQATFHGIRSAPSSS-DSATRDPSTSV---PASGAHQPPQTTEG--------E 844
S G ++ P S TR P + P SGA + ++G E
Sbjct: 866 RSSSCGSTGSSHQSTARGPGGSPQEGTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEE 925
Query: 845 KSPEPLGLPQSQ-SAQALTPPPIPNGSAPE 873
K+ G PQ Q A ++P +P S+PE
Sbjct: 926 KTLRSGGGPQGQEEASGVSPSSLPR-SSPE 954
Score = 35.8 bits (81), Expect = 0.18
Identities = 36/136 (26%), Positives = 48/136 (35%), Gaps = 12/136 (8%)
Query: 624 EEEEDEEEAQGSGES-DGEDGAWQGSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEEEE 682
E +E EEEAQ E + + + + G + G E E E+E + E
Sbjct: 2165 EAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPE 2224
Query: 683 DEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFD-----------PVPTDAPTSPRVSG 731
E A G A P S + G + D PVP D PT P G
Sbjct: 2225 PEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPG 2284
Query: 732 EEELHTGPPAPQGPLS 747
+ H P + GP S
Sbjct: 2285 GDTPHQRPGSQTGPSS 2300
Score = 32.7 bits (73), Expect = 1.5
Identities = 50/200 (25%), Positives = 69/200 (34%), Gaps = 23/200 (11%)
Query: 694 GATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLP 753
G+T S+ S P G T P PT +P P A LS + L
Sbjct: 871 GSTGSSHQSTARGPGGSPQEGTRQPGPTPSP-GPNSGASRRSSASQGAGSRGLSEEKTL- 928
Query: 754 TQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGD--LQATFHGI 811
+S P ++ S P S+P+ P P + D A G+
Sbjct: 929 -RSGGGPQGQEEASGVSPSSLPRSSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGL 987
Query: 812 RSAPSSSDSATRDPSTSVPASGAHQP----PQTTEGE--KSPEPLG-LPQSQSAQALTPP 864
R DP G +P Q+ EG+ + PEP G L S +
Sbjct: 988 RGPEV-------DPGDDHSLEGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGE 1040
Query: 865 PIPNGSAPEG----PASPGS 880
+P G+APEG PA G+
Sbjct: 1041 GVPQGAAPEGVSEAPAEAGA 1060
Score = 30.8 bits (68), Expect = 5.8
Identities = 48/197 (24%), Positives = 72/197 (36%), Gaps = 28/197 (14%)
Query: 693 GGATPLSYPSPGPQP-PGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQG------- 744
GG+ PGP P PGP+ A+ + S +S E+ L +G PQG
Sbjct: 885 GGSPQEGTRQPGPTPSPGPNSGASRRSSASQGAGSRGLSEEKTLRSGG-GPQGQEEASGV 943
Query: 745 -----PLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALV 799
P S P+ + + L + P L A G +V +P +L
Sbjct: 944 SPSSLPRSSPEAVVREWLDNIPEEPILMTYELADETTGAAGGGLRGPEV-DPGDD-HSLE 1001
Query: 800 SIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQ 859
+G+ A + S DP GA T G +S E G+PQ + +
Sbjct: 1002 GLGE---------PAQAGQQSLEGDPGQDPEPEGALLGSSDT-GPQSGE--GVPQGAAPE 1049
Query: 860 ALTPPPIPNGSAPEGPA 876
++ P G+ E PA
Sbjct: 1050 GVSEAPAEAGADREAPA 1066
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 59.3 bits (142), Expect = 2e-08
Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 9/119 (7%)
Query: 621 DDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEE 680
+++EEEE+EEE +G GE + E+G + + G LG+ V G DS++EEEEDEE
Sbjct: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEES 466
Query: 681 -----EEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEE 734
E ++ G GG S+ + G Q T F D+ + +EE
Sbjct: 467 SSEGLEAEDWAQGVVEAGG----SFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521
Score = 45.1 bits (105), Expect = 3e-04
Identities = 36/131 (27%), Positives = 62/131 (47%), Gaps = 19/131 (14%)
Query: 570 GFNDEEFGEQEESVNAPFDKTANITFSLNADDENPNANLLEICYKDRIQQ---FDDDEEE 626
G +EE E+EE ++ ++E E+ ++ +++ D DEEE
Sbjct: 405 GEEEEEEEEEEEEEEGEGEEEEEE----GEEEEEEGGEGEELGEEEEVEEEGDVDSDEEE 460
Query: 627 EDEEE-----------AQGSGESDGEDGAWQGSQLARGARLG-QPPGVRSGGSTDSEDEE 674
E++EE AQG E+ G GA+ + A+ L G S ++ ED+E
Sbjct: 461 EEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDE 520
Query: 675 EEDEEEEEDEE 685
EED+E+E+D++
Sbjct: 521 EEDDEDEDDDD 531
Score = 34.7 bits (78), Expect = 0.40
Identities = 23/48 (47%), Positives = 26/48 (54%), Gaps = 6/48 (12%)
Query: 644 AWQG---SQLA---RGARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEE 685
AWQ S +A R A G P S SE EEEE+EEEEE+EE
Sbjct: 371 AWQAVEPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEE 418
Score = 31.6 bits (70), Expect = 3.4
Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 4/37 (10%)
Query: 662 VRSGGSTDSEDEEEEDEE----EEEDEEGIGCAARGG 694
++S G + E+EEEE+EE EEE+EEG GG
Sbjct: 401 LKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGG 437
Score = 30.4 bits (67), Expect = 7.5
Identities = 12/28 (42%), Positives = 18/28 (64%)
Query: 615 DRIQQFDDDEEEEDEEEAQGSGESDGED 642
D + +DDEEE+DE+E E DG++
Sbjct: 511 DSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 58.2 bits (139), Expect = 3e-08
Identities = 55/192 (28%), Positives = 77/192 (40%), Gaps = 16/192 (8%)
Query: 695 ATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPT 754
++PL+ PSP PP PS + +P+ T P + G P Q S P
Sbjct: 292 SSPLATPSPSA-PPSPSAPPSLQTLPSPPATPP---SQATTSLGSPTLQATHSFLPSPPL 347
Query: 755 QSLASPPARD----ALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHG 810
LA+PP + AL P+PP++P S + PS +++ LQA F
Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSPPASPPL----SPLATPSPQAPNALAVHLLQAPF-- 401
Query: 811 IRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQ-ALTPPPIPNG 869
PS A P S P S + PP + PL +P S A ++P P
Sbjct: 402 -SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460
Query: 870 SAPEGPASPGSQ 881
AP A+P Q
Sbjct: 461 QAPPPLAAPPLQ 472
Score = 53.5 bits (127), Expect = 8e-07
Identities = 54/179 (30%), Positives = 70/179 (39%), Gaps = 24/179 (13%)
Query: 702 SPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPP 761
+P PP P A F P P P SP + + AP PL VP P ASPP
Sbjct: 399 APFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAP--PLQVPPSPP----ASPP 451
Query: 762 ARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSS-SDS 820
S P P + P A ++ +P ++ LQA + S P+S
Sbjct: 452 MSP-----SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA----LPSPPASFPGQ 502
Query: 821 ATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPG 879
A PS S+P S PP ++P L P Q + PP P AP P +PG
Sbjct: 503 APFSPSASLPMSPLATPPP-----QAPPVLAAPLLQVPPS--PPASPTLQAPRRPPTPG 554
Score = 47.8 bits (112), Expect = 5e-05
Identities = 65/268 (24%), Positives = 86/268 (32%), Gaps = 55/268 (20%)
Query: 652 RGARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEG---------IGCAARGGATPLSYPS 702
+G R+ V G +T++ D G + +R T + P
Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182
Query: 703 PGPQP-PGPSWTATFDPVPTDAPTSPRVSGEEELHTGP-------PAPQGPLSVPQGLPT 754
P P P P PT+ P S E T P P+ G L P
Sbjct: 183 PAPSARPRP---------PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233
Query: 755 QSLASP---PARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGI 811
S A+P PAR R P Q +G + P Q D +
Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP---QVTPPRKDAAPALGPL 290
Query: 812 RSAPSSSDSATRDPSTSVPAS-------GAHQPPQTTEGEKSP--------------EPL 850
S+P ++ S + PS S P S A P Q T SP PL
Sbjct: 291 SSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350
Query: 851 GLPQSQSAQALTPPPIPNGSAPEGPASP 878
P Q+ AL PP+ + P PASP
Sbjct: 351 ATPPPQAPPALALPPLQ--APPSPPASP 376
Score = 42.0 bits (97), Expect = 0.003
Identities = 54/194 (27%), Positives = 65/194 (33%), Gaps = 23/194 (11%)
Query: 697 PLSYPSPGPQ-PPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGP--LSVPQGLP 753
P S +P Q PP P + P T P +P L P PQ P L+ P P
Sbjct: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP---P 488
Query: 754 TQSLASPPA----------RDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGD 803
Q+L SPPA +L + PP AP PS P
Sbjct: 489 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP-----T 543
Query: 804 LQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTP 863
LQA P +S S R T A G PP + P S SA +
Sbjct: 544 LQAPRRPPTPGPDTSVSGPR--LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 601
Query: 864 PPIPNGSAPEGPAS 877
S PEG A+
Sbjct: 602 ELRGYDSGPEGGAA 615
Score = 39.7 bits (91), Expect = 0.012
Identities = 51/189 (26%), Positives = 65/189 (34%), Gaps = 27/189 (14%)
Query: 703 PGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGP-LSVPQGLPT----QSL 757
PG P PS + P+ T P +P V L P P P L P+ PT S+
Sbjct: 500 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 559
Query: 758 ASPPARDALQLRSQDPTPPS-APQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPS 816
+ P R L L P PPS +P G + S+ S G S P
Sbjct: 560 SGP--RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS------SATSTPEELRGYDSGPE 611
Query: 817 SSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSA----- 871
+A+ P + A P + G PL + A PP GSA
Sbjct: 612 GGAAASPPPDAELAAC---HPAAWSRG--PAPPLAFRGAPGAPLPWPPATGPGSADGLCT 666
Query: 872 ---PEGPAS 877
EGP S
Sbjct: 667 IYETEGPES 675
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 57.0 bits (136), Expect = 8e-08
Identities = 55/226 (24%), Positives = 81/226 (35%), Gaps = 33/226 (14%)
Query: 622 DDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEEE 681
+DEE + + +SDGE+ + S+ + + S S+ S E E+EE
Sbjct: 1007 EDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEE 1066
Query: 682 EDEEGIGCAARGGATPLSYPSPGPQP---PGPSWTATFDPVPTDAPTSPRVSGEEELHTG 738
E+E P + PS P P P P+ P P + P RV+G T
Sbjct: 1067 EEER-----------PAALPSASPPPREVPVPT------PAPVEVPVPERVAGSPV--TP 1107
Query: 739 PPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQAL 798
P + + P G +S S P R P PP+ P A PS+P L
Sbjct: 1108 LPEQEASPARPAGPTEESPPSAPLR--------PPEPPAGP-PAPAPRPDERPSSPIPLL 1158
Query: 799 VSIGDLQAT--FHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTE 842
+ T F I P+ P P + + P+ E
Sbjct: 1159 PPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRGVE 1204
Score = 44.3 bits (103), Expect = 5e-04
Identities = 64/279 (22%), Positives = 94/279 (33%), Gaps = 72/279 (25%)
Query: 623 DEEEEDEEEAQGSGES----------DGEDGAWQGSQLARGA--RLGQPPGVRSGGSTDS 670
+E+E+D E+ + +GE D E G QG A G+ S D
Sbjct: 919 EEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDE 978
Query: 671 EDEEEEDEEEE-----------------EDEEGIGC------AARGGATPLSYPSPGPQP 707
ED+EE++E+E+ EDEE A G + S
Sbjct: 979 EDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSS 1038
Query: 708 PGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQ 767
S +++ + + +S S E+E PA LP+ ASPP R+
Sbjct: 1039 SSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPA---------ALPS---ASPPPREV-- 1084
Query: 768 LRSQDPTPPSAPQEATEGSKVT-EPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPS 826
P P AP E +V P P +S + P+
Sbjct: 1085 -----PVPTPAPVEVPVPERVAGSPVTPL-----------------PEQEASPARPAGPT 1122
Query: 827 TSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPP 865
P S +PP+ G +P P + S L PPP
Sbjct: 1123 EESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPP 1161
Score = 37.4 bits (85), Expect = 0.062
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 584 NAPFDKTANITFSLNADDENPNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDG 643
++P D+ + A+ E P L+ ++ ++ +++ EEE+EE + S SDGE G
Sbjct: 1329 SSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGE-G 1387
Query: 644 AWQGSQLARGARLGQPP 660
A + L AR +PP
Sbjct: 1388 ALRRRSLRSHARRRRPP 1404
Score = 33.9 bits (76), Expect = 0.68
Identities = 49/210 (23%), Positives = 70/210 (33%), Gaps = 35/210 (16%)
Query: 697 PLSYPSPGPQPPGPSWTATF---DPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLP 753
P + +P P+PP P P + TSPR + +G PAP+ + + +P
Sbjct: 427 PPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPAR--SGSPAPE---TTNESVP 481
Query: 754 TQSLASPPARDALQLRSQDPTPPSAPQEATE--------------GSKVTE-----PSAP 794
+S +R + L+ Q + E GS+V P P
Sbjct: 482 FAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTP 541
Query: 795 CQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQ 854
A + D+ T G A S A S +SG + SP P P
Sbjct: 542 PPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPP 601
Query: 855 SQSAQALTPPP--------IPNGSAPEGPA 876
Q PPP +P G P PA
Sbjct: 602 QQPPPPPPPPPPPPPYLASLPLGYPPHQPA 631
Score = 30.4 bits (67), Expect = 7.5
Identities = 47/185 (25%), Positives = 67/185 (36%), Gaps = 43/185 (23%)
Query: 609 LEICYKDRIQQFD---DDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQ---PPG- 661
+E+ K++ +F D EEE+E + G D GS++ G+ G PP
Sbjct: 492 IEMLLKEQRSKFSFLASDTEEEEENSSMVLGARD------TGSEVPSGSGHGPCTPPPAP 545
Query: 662 -----VRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATF 716
V GS + E + +++ C++ G +S G PP
Sbjct: 546 ANFEDVAPTGSGEPGATRESPKANGQNQAS-PCSS-GDDMEISDDDRGGSPP-------- 595
Query: 717 DPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQL--RSQDPT 774
P PT P P PP P P P L + L PP + A L R P
Sbjct: 596 -PAPTP-PQQP-----------PPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPP 642
Query: 775 PPSAP 779
PP P
Sbjct: 643 PPEYP 647
Score = 30.0 bits (66), Expect = 9.9
Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
Query: 663 RSGGSTDSEDEEEEDEEEEED----EEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDP 718
R G + E+E EE+EEE D +G G R + P PP P ++P
Sbjct: 1358 REEGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPPPRAYEP 1417
>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
isoform 1 [Homo sapiens]
Length = 824
Score = 57.0 bits (136), Expect = 8e-08
Identities = 72/240 (30%), Positives = 98/240 (40%), Gaps = 28/240 (11%)
Query: 617 IQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGST-------- 668
+++FDD++ E ++ G G S D + S L+ G R QP + S
Sbjct: 29 LEEFDDEDLSEITDDC-GLGLSYDSDHCEKDS-LSLG-RSEQPHPICSFQDDFQEFEMID 85
Query: 669 DSEDEEEEDEEEE-EDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPT------ 721
D+E+E++EDEEEE E+EEG G GG P+PGP P PS PT
Sbjct: 86 DNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTT 145
Query: 722 -DAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASP-PARDALQLRSQDPTPPSAP 779
A S +G +L + L P + L P PA D +Q P P
Sbjct: 146 LGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCD 205
Query: 780 QEATEGSKVTEPSAPCQALVSI-----GDLQATFHGIRSAPSSSDSATRDPSTSVPASGA 834
EG++ EP AP S DL++ G R SS + S S A GA
Sbjct: 206 ---CEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGA 262
Score = 46.6 bits (109), Expect = 1e-04
Identities = 74/314 (23%), Positives = 110/314 (35%), Gaps = 50/314 (15%)
Query: 615 DRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGS---TDSE 671
D ++ DD++EEE+EEE +G GE G++G GS+ L P V T
Sbjct: 85 DDNEEEDDEDEEEEEEEEEGDGE--GQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLR 142
Query: 672 DEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQP----PGPSWTATFDPVPTDAPTSP 727
++ + G + SP P+ PGP P +P P
Sbjct: 143 LTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRP 202
Query: 728 RVSGEEELHTGPPAPQG--PLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEG 785
E PPAP G P S P G+ + + SQ+ + P + E G
Sbjct: 203 GCDCEGNRPAEPPAPGGTSPSSDP-GIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGG 261
Query: 786 SK----VTEPSAPCQALVSIGDLQATFHGIR--------SAPSSSDSATRDP-------- 825
++ ++ S L S G ++ S+P+S R+P
Sbjct: 262 ARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLP 321
Query: 826 -----STSVPASGAHQPPQTTEGEKSPEPL-----------GLPQSQSAQALTPPPIPNG 869
+ S SG+ P +E SP L P Q L+P P P G
Sbjct: 322 VGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPG 381
Query: 870 S--APEGPASPGSQ 881
+P G A+ SQ
Sbjct: 382 EPVSPAGGAAQDSQ 395
Score = 33.9 bits (76), Expect = 0.68
Identities = 56/235 (23%), Positives = 84/235 (35%), Gaps = 17/235 (7%)
Query: 653 GARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSW 712
G R +PP GG++ S D E + G G R + LS P + G +
Sbjct: 208 GNRPAEPPA--PGGTSPSSDPGIEADLRSRSSGGRG--GRRSSQELSSPGSDSEDAGGAR 263
Query: 713 TATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQD 772
+ + + T +S + + + S+ + S PP R+ + +
Sbjct: 264 LGRM--ISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP-REPPRRPAFL 320
Query: 773 PTPPSAPQEATEGSKVTEP--SAPCQALVSIGDLQATFHGIRSAP-----SSSDSATRDP 825
P P E +EP S + + +L + S+P A R P
Sbjct: 321 PVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPP 380
Query: 826 STSV-PASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPG 879
V PA GA Q Q E P + L ++ A PPP P P GPA PG
Sbjct: 381 GEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA-PPPPAPAAPRP-GPAQPG 433
Score = 33.1 bits (74), Expect = 1.2
Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 13/52 (25%)
Query: 660 PGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPS 711
PG R+ + SE+E+EED+EEEED E S SPG + GPS
Sbjct: 459 PG-RACSAACSEEEDEEDDEEEEDAED------------SAGSPGGRGTGPS 497
>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
potassium channel 4 [Homo sapiens]
Length = 1203
Score = 56.6 bits (135), Expect = 1e-07
Identities = 62/229 (27%), Positives = 89/229 (38%), Gaps = 15/229 (6%)
Query: 655 RLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSY-PSPGPQPPG--PS 711
+LGQPPG S G E + + + A GGA+P+ + P G PPG P
Sbjct: 974 QLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGASGGASPVGFTPRGGLSPPGHSPG 1033
Query: 712 WTATFDPVPTDAPTSPRVSGEEELHTGPPAPQ-GPLSVPQGLPTQSLASPPARDALQLRS 770
TF P PR SG PPA P VPQ T L P R L+
Sbjct: 1034 PPRTFPSAP------PRASGSHGSLLLPPASSPPPPQVPQRRGTPPLT--PGRLTQDLKL 1085
Query: 771 QDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSD-SATRDPSTSV 829
+ P+ PQ+ + + P + +++ + G + SS P ++
Sbjct: 1086 ISASQPALPQDGAQTLRRASPHSSGESMAAFPLFPRAGGGSGGSGSSGGLGPPGRPYGAI 1145
Query: 830 PASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASP 878
P P +T+ G P PL L ++ A + PP+ G E A P
Sbjct: 1146 PGQHVTLPRKTSSG-SLPPPLSLFGAR-ATSSGGPPLTAGPQREPGARP 1192
Score = 38.1 bits (87), Expect = 0.036
Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 15/107 (14%)
Query: 627 EDEEEAQGSGES--DGEDGAWQGSQLARGARLGQPPGVRSGGS----TDSEDEE----EE 676
+ E A+G+G+S +G+ ++GS + G+R G G SG S DS +E E
Sbjct: 76 DSEGPARGAGKSSTNGDCRRFRGSLASLGSRGGGSGGTGSGSSHGHLHDSAEERRLIAEG 135
Query: 677 DEEEEEDEEGIGCAAR-----GGATPLSYPSPGPQPPGPSWTATFDP 718
D ED G AA A P + P P QPP P+ + P
Sbjct: 136 DASPGEDRTPPGLAAEPERPGASAQPAASPPPPQQPPQPASASCEQP 182
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 56.6 bits (135), Expect = 1e-07
Identities = 69/237 (29%), Positives = 84/237 (35%), Gaps = 38/237 (16%)
Query: 676 EDEEEEEDEEGI-----GCAARGGATPLSYPSPGPQPPGPSWTATFDPV----PTDAPTS 726
ED +EE I G +GG P PSP +P GP P P P
Sbjct: 21 EDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 80
Query: 727 PRVSGEEELHTGPPA--PQGPLSVPQGLPTQSLASPPAR------DALQLRSQDPTPPSA 778
P G + PP PQGP PQG ++S SPP + P PP
Sbjct: 81 PPPQGGNKPQGPPPPGKPQGP--PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 138
Query: 779 PQEATE--GSKVTEPSAPC--QALVSIGDLQATFHGIRSAPSSSDSAT----RDPSTSVP 830
PQ G+K P P Q GD ++ RS P P P
Sbjct: 139 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS--RSSRSPPGKPQGPPPQGGNQPQGPPP 196
Query: 831 ASGAHQ--PPQTTEGEKSPEPLGLPQ-------SQSAQALTPPPIPNGSAPEGPASP 878
G Q PPQ + P P G PQ ++S A +PP P G P+G P
Sbjct: 197 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP 253
Score = 50.1 bits (118), Expect = 9e-06
Identities = 67/248 (27%), Positives = 83/248 (33%), Gaps = 49/248 (19%)
Query: 657 GQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATF 716
G PP + G D+ +G +GG P P P +P GP
Sbjct: 91 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPP----- 143
Query: 717 DPVPTDAPTSPRVSGEEELHTGPPAPQG---------PLSVPQGLPTQSLASPPARDALQ 767
P + P P G+ + GPP PQG P PQG P Q P
Sbjct: 144 -PQGGNKPQGPPPPGKPQ---GPP-PQGDNKSRSSRSPPGKPQGPPPQGGNQPQG----- 193
Query: 768 LRSQDPTPPSAPQEATE--GSKVTEPSAPC--QALVSIGDLQATFHGIRSAPSSSDSAT- 822
P PP PQ G+K P P Q GD ++ RS P
Sbjct: 194 ----PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS--QSARSPPGKPQGPPP 247
Query: 823 ---RDPSTSVPASGAHQ--PPQTTEGEKSPEPLGLPQ-------SQSAQALTPPPIPNGS 870
P P G Q PPQ + P P G PQ S+S + +PP P G
Sbjct: 248 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP 307
Query: 871 APEGPASP 878
P+G P
Sbjct: 308 PPQGGNQP 315
Score = 45.8 bits (107), Expect = 2e-04
Identities = 65/252 (25%), Positives = 80/252 (31%), Gaps = 34/252 (13%)
Query: 646 QGSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPG- 704
QG +R +R PPG G ++ + +G +GG P P PG
Sbjct: 165 QGDNKSRSSR--SPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGGNKPQGPPPPGK 220
Query: 705 PQPPGPSWTATFDPV--PTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPA 762
PQ P P P P P G + GPP P G PQG P Q P
Sbjct: 221 PQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ-GPPPPPGK---PQGPPPQGGNKP-- 274
Query: 763 RDALQLRSQDPTPPSAPQEATE--GSKV----TEPSAPCQALVSIGDLQATFHGIRSAPS 816
Q P PP PQ GSK + P P G+ P
Sbjct: 275 --------QGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 326
Query: 817 SSDSATRDPSTSVPASGAHQPPQTTEGEKSP-------EPLGLPQSQSAQALTPPPIPNG 869
+ P G Q P G KS +P G PQ + PPP G
Sbjct: 327 GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGG 386
Query: 870 SAPEGPASPGSQ 881
+ + A P Q
Sbjct: 387 NPQQPQAPPAGQ 398
Score = 32.3 bits (72), Expect = 2.0
Identities = 38/141 (26%), Positives = 46/141 (32%), Gaps = 31/141 (21%)
Query: 657 GQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGP---SWT 713
G+P G G + S + + G +GG P P P +P GP
Sbjct: 281 GKPQGPPPQGGSKSRSSRSPPGKPQ------GPPPQGGNQPQGPPPPPGKPQGPPPQGGN 334
Query: 714 ATFDPVPTDAPTSPRVSGEEELHT---------GPPA-----PQGPLSVPQGLPTQSLAS 759
P P P P G + + GPP PQGP G P Q A
Sbjct: 335 KPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA- 393
Query: 760 PPARDALQLRSQDPTPPSAPQ 780
PPA Q PP PQ
Sbjct: 394 PPA-------GQPQGPPRPPQ 407
Score = 32.0 bits (71), Expect = 2.6
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 15/91 (16%)
Query: 804 LQATFHGIRSAPSSSDSATRDPSTSVPASGAH-QPPQ---TTEGEKSP--EPLGLPQSQS 857
L + SA + ++ +++ S S+ A PPQ +G SP +P G P
Sbjct: 6 LSVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGG 65
Query: 858 AQALTPPPIPN---------GSAPEGPASPG 879
Q PPP P G+ P+GP PG
Sbjct: 66 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 96
>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 56.2 bits (134), Expect = 1e-07
Identities = 50/177 (28%), Positives = 68/177 (38%), Gaps = 30/177 (16%)
Query: 711 SWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVP--QGLPTQSLASPPARDALQL 768
S AT PV + AP ++ PP P P P ++ A+PP A
Sbjct: 149 SSVATLAPVNSPAP--------QDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSA--- 197
Query: 769 RSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTS 828
+Q P SAP E T + P SAP + +A PS +
Sbjct: 198 TTQAPPSSSAPPETTAAPPTPPATTPAPP-------------SSSAPPETTAAPPTPSAT 244
Query: 829 VPAS-GAHQPPQTTEGEKSPEPLGL-PQSQSA--QALTPPPIPNGSAPEGPASPGSQ 881
PA + PP+TT +P L P S SA + PP P+ + P P+SP Q
Sbjct: 245 TPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQ 301
Score = 53.1 bits (126), Expect = 1e-06
Identities = 53/173 (30%), Positives = 65/173 (37%), Gaps = 28/173 (16%)
Query: 708 PGPSWTATFDPVPT-DAPTSPRVSGEEELHTGPPAPQGPLSVP--QGLPTQSLASPPARD 764
P P T P P+ P P S E PP P P P ++ A+PP
Sbjct: 160 PAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPP 219
Query: 765 ALQLRSQDPTPP--SAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSAT 822
A P PP SAP E T PSA A +S SAP + +
Sbjct: 220 A-----TTPAPPSSSAPPETTAAPPT--PSATTPAPLS-----------SSAPPETTAVP 261
Query: 823 RDPS-TSVPASGAHQPPQTTEGEKSPEPL--GLPQSQSAQALTPPPI--PNGS 870
PS T++ S A PP+TT +P P S + Q T PI PN S
Sbjct: 262 PTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSS 314
Score = 49.7 bits (117), Expect = 1e-05
Identities = 45/163 (27%), Positives = 59/163 (36%), Gaps = 10/163 (6%)
Query: 696 TPLSYPSPGPQPPGPSWTATFDPVP-TDAPTSPRVSGEEELHTGPPAPQG--PLSVPQGL 752
TP + P P T P P P P S E PP P P +
Sbjct: 194 TPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSA 253
Query: 753 PTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIR 812
P ++ A PP A L DP+ SAP E T PSA A S Q T
Sbjct: 254 PPETTAVPPTPSATTL---DPSSASAPPETTAAPPT--PSATTPAPPSSPAPQETTAAPI 308
Query: 813 SAPSSSDSATRDPSTSVPASGAHQPPQ--TTEGEKSPEPLGLP 853
+ P+SS + ++ A+ HQ TT+ + +P P
Sbjct: 309 TTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP 351
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/182 (26%), Positives = 62/182 (34%), Gaps = 28/182 (15%)
Query: 696 TPLSYPSPGPQPPGPSWTATFDPVP---TDAPTSPRVSGEEELHTGPPAPQGPLSVP--Q 750
TP + P P T P P T AP P S E PP P P
Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAP--PSSSAPPETTAAPPTPPATTPAPPSS 228
Query: 751 GLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHG 810
P ++ A+PP A + P SAP E T P P +
Sbjct: 229 SAPPETTAAPPTPSA---TTPAPLSSSAPPETT-----AVPPTPSATTLDPSS------- 273
Query: 811 IRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGS 870
SAP + +A PS + PA + PQ E + P+ P S S L P +
Sbjct: 274 -ASAPPETTAAPPTPSATTPAPPSSPAPQ----ETTAAPITTPNS-SPTTLAPDTSETSA 327
Query: 871 AP 872
AP
Sbjct: 328 AP 329
Score = 33.5 bits (75), Expect = 0.89
Identities = 42/169 (24%), Positives = 62/169 (36%), Gaps = 14/169 (8%)
Query: 718 PVPTDAPTSPRVSGEEELHTGPPAPQGPLSV--PQGLPTQSLASPPARDALQLRSQDPTP 775
P P + P P H P P SV P + T + S A + P
Sbjct: 76 PSPNNPPKFPNP------HQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNV 129
Query: 776 PSAPQEATE-GSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGA 834
PQ AT S+ ++ A ++ + A + P+ S + PS+S P
Sbjct: 130 TFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETT 189
Query: 835 HQPPQTTEGEKSPEPLGLPQSQSAQALTPP---PIPNGSA--PEGPASP 878
PP + ++P P +A TPP P P S+ PE A+P
Sbjct: 190 AAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAP 238
>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 56.2 bits (134), Expect = 1e-07
Identities = 50/177 (28%), Positives = 68/177 (38%), Gaps = 30/177 (16%)
Query: 711 SWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVP--QGLPTQSLASPPARDALQL 768
S AT PV + AP ++ PP P P P ++ A+PP A
Sbjct: 149 SSVATLAPVNSPAP--------QDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSA--- 197
Query: 769 RSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTS 828
+Q P SAP E T + P SAP + +A PS +
Sbjct: 198 TTQAPPSSSAPPETTAAPPTPPATTPAPP-------------SSSAPPETTAAPPTPSAT 244
Query: 829 VPAS-GAHQPPQTTEGEKSPEPLGL-PQSQSA--QALTPPPIPNGSAPEGPASPGSQ 881
PA + PP+TT +P L P S SA + PP P+ + P P+SP Q
Sbjct: 245 TPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQ 301
Score = 53.1 bits (126), Expect = 1e-06
Identities = 53/173 (30%), Positives = 65/173 (37%), Gaps = 28/173 (16%)
Query: 708 PGPSWTATFDPVPT-DAPTSPRVSGEEELHTGPPAPQGPLSVP--QGLPTQSLASPPARD 764
P P T P P+ P P S E PP P P P ++ A+PP
Sbjct: 160 PAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPP 219
Query: 765 ALQLRSQDPTPP--SAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSAT 822
A P PP SAP E T PSA A +S SAP + +
Sbjct: 220 A-----TTPAPPSSSAPPETTAAPPT--PSATTPAPLS-----------SSAPPETTAVP 261
Query: 823 RDPS-TSVPASGAHQPPQTTEGEKSPEPL--GLPQSQSAQALTPPPI--PNGS 870
PS T++ S A PP+TT +P P S + Q T PI PN S
Sbjct: 262 PTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSS 314
Score = 49.7 bits (117), Expect = 1e-05
Identities = 45/163 (27%), Positives = 59/163 (36%), Gaps = 10/163 (6%)
Query: 696 TPLSYPSPGPQPPGPSWTATFDPVP-TDAPTSPRVSGEEELHTGPPAPQG--PLSVPQGL 752
TP + P P T P P P P S E PP P P +
Sbjct: 194 TPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSA 253
Query: 753 PTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIR 812
P ++ A PP A L DP+ SAP E T PSA A S Q T
Sbjct: 254 PPETTAVPPTPSATTL---DPSSASAPPETTAAPPT--PSATTPAPPSSPAPQETTAAPI 308
Query: 813 SAPSSSDSATRDPSTSVPASGAHQPPQ--TTEGEKSPEPLGLP 853
+ P+SS + ++ A+ HQ TT+ + +P P
Sbjct: 309 TTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP 351
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/182 (26%), Positives = 62/182 (34%), Gaps = 28/182 (15%)
Query: 696 TPLSYPSPGPQPPGPSWTATFDPVP---TDAPTSPRVSGEEELHTGPPAPQGPLSVP--Q 750
TP + P P T P P T AP P S E PP P P
Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAP--PSSSAPPETTAAPPTPPATTPAPPSS 228
Query: 751 GLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHG 810
P ++ A+PP A + P SAP E T P P +
Sbjct: 229 SAPPETTAAPPTPSA---TTPAPLSSSAPPETT-----AVPPTPSATTLDPSS------- 273
Query: 811 IRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGS 870
SAP + +A PS + PA + PQ E + P+ P S S L P +
Sbjct: 274 -ASAPPETTAAPPTPSATTPAPPSSPAPQ----ETTAAPITTPNS-SPTTLAPDTSETSA 327
Query: 871 AP 872
AP
Sbjct: 328 AP 329
Score = 33.5 bits (75), Expect = 0.89
Identities = 42/169 (24%), Positives = 62/169 (36%), Gaps = 14/169 (8%)
Query: 718 PVPTDAPTSPRVSGEEELHTGPPAPQGPLSV--PQGLPTQSLASPPARDALQLRSQDPTP 775
P P + P P H P P SV P + T + S A + P
Sbjct: 76 PSPNNPPKFPNP------HQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNV 129
Query: 776 PSAPQEATE-GSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGA 834
PQ AT S+ ++ A ++ + A + P+ S + PS+S P
Sbjct: 130 TFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETT 189
Query: 835 HQPPQTTEGEKSPEPLGLPQSQSAQALTPP---PIPNGSA--PEGPASP 878
PP + ++P P +A TPP P P S+ PE A+P
Sbjct: 190 AAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAP 238
>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 56.2 bits (134), Expect = 1e-07
Identities = 50/177 (28%), Positives = 68/177 (38%), Gaps = 30/177 (16%)
Query: 711 SWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVP--QGLPTQSLASPPARDALQL 768
S AT PV + AP ++ PP P P P ++ A+PP A
Sbjct: 149 SSVATLAPVNSPAP--------QDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSA--- 197
Query: 769 RSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTS 828
+Q P SAP E T + P SAP + +A PS +
Sbjct: 198 TTQAPPSSSAPPETTAAPPTPPATTPAPP-------------SSSAPPETTAAPPTPSAT 244
Query: 829 VPAS-GAHQPPQTTEGEKSPEPLGL-PQSQSA--QALTPPPIPNGSAPEGPASPGSQ 881
PA + PP+TT +P L P S SA + PP P+ + P P+SP Q
Sbjct: 245 TPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQ 301
Score = 53.1 bits (126), Expect = 1e-06
Identities = 53/173 (30%), Positives = 65/173 (37%), Gaps = 28/173 (16%)
Query: 708 PGPSWTATFDPVPT-DAPTSPRVSGEEELHTGPPAPQGPLSVP--QGLPTQSLASPPARD 764
P P T P P+ P P S E PP P P P ++ A+PP
Sbjct: 160 PAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPP 219
Query: 765 ALQLRSQDPTPP--SAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSAT 822
A P PP SAP E T PSA A +S SAP + +
Sbjct: 220 A-----TTPAPPSSSAPPETTAAPPT--PSATTPAPLS-----------SSAPPETTAVP 261
Query: 823 RDPS-TSVPASGAHQPPQTTEGEKSPEPL--GLPQSQSAQALTPPPI--PNGS 870
PS T++ S A PP+TT +P P S + Q T PI PN S
Sbjct: 262 PTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSS 314
Score = 49.7 bits (117), Expect = 1e-05
Identities = 45/163 (27%), Positives = 59/163 (36%), Gaps = 10/163 (6%)
Query: 696 TPLSYPSPGPQPPGPSWTATFDPVP-TDAPTSPRVSGEEELHTGPPAPQG--PLSVPQGL 752
TP + P P T P P P P S E PP P P +
Sbjct: 194 TPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSA 253
Query: 753 PTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIR 812
P ++ A PP A L DP+ SAP E T PSA A S Q T
Sbjct: 254 PPETTAVPPTPSATTL---DPSSASAPPETTAAPPT--PSATTPAPPSSPAPQETTAAPI 308
Query: 813 SAPSSSDSATRDPSTSVPASGAHQPPQ--TTEGEKSPEPLGLP 853
+ P+SS + ++ A+ HQ TT+ + +P P
Sbjct: 309 TTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP 351
Score = 44.3 bits (103), Expect = 5e-04
Identities = 49/182 (26%), Positives = 62/182 (34%), Gaps = 28/182 (15%)
Query: 696 TPLSYPSPGPQPPGPSWTATFDPVP---TDAPTSPRVSGEEELHTGPPAPQGPLSVP--Q 750
TP + P P T P P T AP P S E PP P P
Sbjct: 171 TPSATTPAPPSSSAPPETTAAPPTPSATTQAP--PSSSAPPETTAAPPTPPATTPAPPSS 228
Query: 751 GLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHG 810
P ++ A+PP A + P SAP E T P P +
Sbjct: 229 SAPPETTAAPPTPSA---TTPAPLSSSAPPETT-----AVPPTPSATTLDPSS------- 273
Query: 811 IRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGS 870
SAP + +A PS + PA + PQ E + P+ P S S L P +
Sbjct: 274 -ASAPPETTAAPPTPSATTPAPPSSPAPQ----ETTAAPITTPNS-SPTTLAPDTSETSA 327
Query: 871 AP 872
AP
Sbjct: 328 AP 329
Score = 33.5 bits (75), Expect = 0.89
Identities = 42/169 (24%), Positives = 62/169 (36%), Gaps = 14/169 (8%)
Query: 718 PVPTDAPTSPRVSGEEELHTGPPAPQGPLSV--PQGLPTQSLASPPARDALQLRSQDPTP 775
P P + P P H P P SV P + T + S A + P
Sbjct: 76 PSPNNPPKFPNP------HQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNV 129
Query: 776 PSAPQEATE-GSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGA 834
PQ AT S+ ++ A ++ + A + P+ S + PS+S P
Sbjct: 130 TFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETT 189
Query: 835 HQPPQTTEGEKSPEPLGLPQSQSAQALTPP---PIPNGSA--PEGPASP 878
PP + ++P P +A TPP P P S+ PE A+P
Sbjct: 190 AAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAP 238
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 55.8 bits (133), Expect = 2e-07
Identities = 53/189 (28%), Positives = 70/189 (37%), Gaps = 18/189 (9%)
Query: 697 PLSYPSPGPQPPGPSWTA---TFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLP 753
P P P PP P T T + T P +P L P P PL+ P
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
Query: 754 TQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRS 813
LA PP + P+PP++P S + PS +++ LQA F
Sbjct: 622 PPXLALPPLQ-------APPSPPASPPL----SPLATPSPQAPNALAVHLLQAPF---SP 667
Query: 814 APSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQ-ALTPPPIPNGSAP 872
PS A P S P S + PP + PL +P S A ++P P AP
Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
Query: 873 EGPASPGSQ 881
A+P Q
Sbjct: 728 PPLAAPPLQ 736
Score = 52.0 bits (123), Expect = 2e-06
Identities = 54/196 (27%), Positives = 78/196 (39%), Gaps = 18/196 (9%)
Query: 695 ATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELH---TGPPAP--QGPLSVP 749
A P P PP P + P+ T +P +P L + PP+P Q P S P
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 680
Query: 750 QGLPTQSLASPPARDALQLRSQD----PTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQ 805
P A+PP++ L + P+PP++P + + + P A LQ
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA----PPLQ 736
Query: 806 ATFHGIRSAPSSSDSATRDPSTS-VPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPP 864
++P S SAT P + A+ Q P + PL P Q+ AL P
Sbjct: 737 VP-PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP 795
Query: 865 PIPNGSAPEGPAS-PG 879
P+ + P PAS PG
Sbjct: 796 PLQ--ALPSPPASFPG 809
Score = 51.2 bits (121), Expect = 4e-06
Identities = 56/220 (25%), Positives = 76/220 (34%), Gaps = 47/220 (21%)
Query: 695 ATPLSYPSPGPQPPGPSWTATFDPV--PTDAP---TSPRVSGEEELHTGPPAPQGPLSVP 749
ATPL P P P T P P+ AP T+P + L T PP + VP
Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP-----IQVP 392
Query: 750 QGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEG----------SKVTEPSAPCQALV 799
L + SL +PP+ AL + S +AT + +T PS P
Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452
Query: 800 SIGDLQATFHGIRSAPSSSD--------------------SATRDPSTSVPASGAHQPPQ 839
LQA S P + S+ S P S PP
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512
Query: 840 TTEGEKSPEPLGLPQS-------QSAQALTPPPIPNGSAP 872
T+ +P L P + ++ +L PPP+ SAP
Sbjct: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552
Score = 43.9 bits (102), Expect = 7e-04
Identities = 58/183 (31%), Positives = 67/183 (36%), Gaps = 49/183 (26%)
Query: 697 PLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQS 756
PL+ P P PP P + P T P P L PP Q P S P LP
Sbjct: 729 PLAAP-PLQVPPSPPASPPMSPSATPPPRVP------PLLAAPPL-QVPPSPPASLPMSP 780
Query: 757 LASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPS 816
LA PP P + P AT P QAL S A+F G AP
Sbjct: 781 LAKPP-------------PQAPPALAT---------PPLQALPS---PPASFPG--QAPF 813
Query: 817 SSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPA 876
S PS S+P S PP ++P L P Q +PP P AP P
Sbjct: 814 S-------PSASLPMSPLATPP-----PQAPPVLAAPLLQVPP--SPPASPTLQAPRRPP 859
Query: 877 SPG 879
+PG
Sbjct: 860 TPG 862
Score = 42.0 bits (97), Expect = 0.003
Identities = 51/198 (25%), Positives = 68/198 (34%), Gaps = 33/198 (16%)
Query: 697 PLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQS 756
PLS P+ P S + P+ + P + P AP L +P L TQS
Sbjct: 460 PLSLPASPPLQT--SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPP-LETQS 516
Query: 757 LASPPARDALQLRSQDPTPPSAPQEA-----TEGSKVTEP---SAPCQALVSIGDLQATF 808
+PP+ P + P A T + +T P + PC A +
Sbjct: 517 SLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL------- 569
Query: 809 HGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPP--- 865
+ S P P+S A PPQ SP GLP + TPPP
Sbjct: 570 -------QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP 622
Query: 866 -----IPNGSAPEGPASP 878
P + P PASP
Sbjct: 623 PXLALPPLQAPPSPPASP 640
Score = 42.0 bits (97), Expect = 0.003
Identities = 59/220 (26%), Positives = 75/220 (34%), Gaps = 42/220 (19%)
Query: 697 PLSYP-SPGPQPPG---PSWTATFDPVPTDAPTSPRVSGEEELHTGPPAP------QGPL 746
P S P SP PP PS A VP P SP +S P P Q P
Sbjct: 680 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739
Query: 747 SVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQA 806
S P P A+PP R L + P +P + S + +P ++ LQA
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799
Query: 807 TFHGIRSAPSS-SDSATRDPSTSVPASGAHQPPQ---------------------TTEGE 844
+ S P+S A PS S+P S PP T +
Sbjct: 800 ----LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855
Query: 845 KSPEPLGLPQSQSAQALT------PPPIPNGSAPEGPASP 878
+ P G S S LT PPP P+ S + P
Sbjct: 856 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895
Score = 41.2 bits (95), Expect = 0.004
Identities = 58/257 (22%), Positives = 83/257 (32%), Gaps = 48/257 (18%)
Query: 652 RGARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEG---------IGCAARGGATPLSYPS 702
+G R+ V G +T++ D G + +R T + P
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191
Query: 703 PGPQP-PGPSWTATFDPVPTDAPTSPRVSGEEELHTGP-------PAPQGPLSVPQGLPT 754
P P P P PT+ P S E T P P+ G L P
Sbjct: 192 PAPSARPRP---------PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 755 QSLASP---PARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGI 811
S A+P PAR R P Q +G + P Q T
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP------------QVTPPRK 290
Query: 812 RSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTP--PPIPNG 869
+AP+ ++ +T P+ +P + +P P LP S P PP P+
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
Query: 870 -----SAPEGPASPGSQ 881
+ P PA+P SQ
Sbjct: 351 PPSLQTLPSPPATPPSQ 367
Score = 39.7 bits (91), Expect = 0.012
Identities = 51/189 (26%), Positives = 65/189 (34%), Gaps = 27/189 (14%)
Query: 703 PGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGP-LSVPQGLPT----QSL 757
PG P PS + P+ T P +P V L P P P L P+ PT S+
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 867
Query: 758 ASPPARDALQLRSQDPTPPS-APQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPS 816
+ P R L L P PPS +P G + S+ S G S P
Sbjct: 868 SGP--RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS------SATSTPEELRGYDSGPE 919
Query: 817 SSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSA----- 871
+A+ P + A P + G PL + A PP GSA
Sbjct: 920 GGAAASPPPDAELAAC---HPAAWSRG--PAPPLAFRGAPGAPLPWPPATGPGSADGLCT 974
Query: 872 ---PEGPAS 877
EGP S
Sbjct: 975 IYETEGPES 983
Score = 38.5 bits (88), Expect = 0.028
Identities = 55/238 (23%), Positives = 80/238 (33%), Gaps = 34/238 (14%)
Query: 651 ARGARLGQP---PGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPG--- 704
A G +G P P R T+ + E E A R PS G
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR-------PSAGGGL 234
Query: 705 PQPPGPSWTATFDPVPTDAPTSPRVSGEEEL--HTGPPAPQG--PLSVPQGLPTQSLASP 760
+P S +++ P+ + A + P G H P P+G L PQ P + A+P
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294
Query: 761 PARDALQLRSQDPTP--------PSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIR 812
P+P P AT PS P + +
Sbjct: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP------ 348
Query: 813 SAPSSSDSATRDPST---SVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIP 867
SAP S + P+T P S P Q ++ P+ +P S ++ +L PP P
Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406
>gi|7706537 mitogen-activated protein kinase 8 interacting protein 2
isoform 2 [Homo sapiens]
Length = 797
Score = 55.8 bits (133), Expect = 2e-07
Identities = 57/180 (31%), Positives = 73/180 (40%), Gaps = 17/180 (9%)
Query: 669 DSEDEEEEDEEEE-EDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPT------ 721
D+E+E++EDEEEE E+EEG G GG P+PGP P PS PT
Sbjct: 59 DNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTT 118
Query: 722 -DAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASP-PARDALQLRSQDPTPPSAP 779
A S +G +L + L P + L P PA D +Q P P
Sbjct: 119 LGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCD 178
Query: 780 QEATEGSKVTEPSAPCQALVSI-----GDLQATFHGIRSAPSSSDSATRDPSTSVPASGA 834
EG++ EP AP S DL++ G R SS + S S A GA
Sbjct: 179 ---CEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGA 235
Score = 46.2 bits (108), Expect = 1e-04
Identities = 74/326 (22%), Positives = 115/326 (35%), Gaps = 56/326 (17%)
Query: 611 IC-YKDRIQQFD-------DDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGV 662
IC ++D Q+F+ +D+E+E+EEE + G+ +G++G GS+ L P V
Sbjct: 44 ICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSV 103
Query: 663 RSGGS---TDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQP----PGPSWTAT 715
T ++ + G + SP P+ PGP
Sbjct: 104 EEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATD 163
Query: 716 FDPVPTDAPTSPRVSGEEELHTGPPAPQG--PLSVPQGLPTQSLASPPARDALQLRSQDP 773
P +P P E PPAP G P S P G+ + + SQ+
Sbjct: 164 TGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP-GIEADLRSRSSGGRGGRRSSQEL 222
Query: 774 TPPSAPQEATEGSK----VTEPSAPCQALVSIGDLQATFHGIR--------SAPSSSDSA 821
+ P + E G++ ++ S L S G ++ S+P+S
Sbjct: 223 SSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEP 282
Query: 822 TRDP-------------STSVPASGAHQPPQTTEGEKSPEPL-----------GLPQSQS 857
R+P + S SG+ P +E SP L P
Sbjct: 283 PREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCP 342
Query: 858 AQALTPPPIPNGS--APEGPASPGSQ 881
Q L+P P P G +P G A+ SQ
Sbjct: 343 GQCLSPAPRPPGEPVSPAGGAAQDSQ 368
Score = 33.9 bits (76), Expect = 0.68
Identities = 56/235 (23%), Positives = 84/235 (35%), Gaps = 17/235 (7%)
Query: 653 GARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSW 712
G R +PP GG++ S D E + G G R + LS P + G +
Sbjct: 181 GNRPAEPPA--PGGTSPSSDPGIEADLRSRSSGGRG--GRRSSQELSSPGSDSEDAGGAR 236
Query: 713 TATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQD 772
+ + + T +S + + + S+ + S PP R+ + +
Sbjct: 237 LGRM--ISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP-REPPRRPAFL 293
Query: 773 PTPPSAPQEATEGSKVTEP--SAPCQALVSIGDLQATFHGIRSAP-----SSSDSATRDP 825
P P E +EP S + + +L + S+P A R P
Sbjct: 294 PVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPP 353
Query: 826 STSV-PASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPG 879
V PA GA Q Q E P + L ++ A PPP P P GPA PG
Sbjct: 354 GEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA-PPPPAPAAPRP-GPAQPG 406
Score = 33.1 bits (74), Expect = 1.2
Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 13/52 (25%)
Query: 660 PGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPS 711
PG R+ + SE+E+EED+EEEED E S SPG + GPS
Sbjct: 432 PG-RACSAACSEEEDEEDDEEEEDAED------------SAGSPGGRGTGPS 470
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 55.5 bits (132), Expect = 2e-07
Identities = 48/188 (25%), Positives = 82/188 (43%), Gaps = 10/188 (5%)
Query: 697 PLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQS 756
P S + P P P+ A P P + P SP + PAP P P+ + +
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEE-PASPAAAVPTPEEPAFPAPAVP--TPEESASAA 1160
Query: 757 LASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPS 816
+A P ++ + PTP + A + + EP++P ++ + + AT S P+
Sbjct: 1161 VAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS-PA 1219
Query: 817 SSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSA----P 872
+S + +P++ A+ P + T + L P S +A LTP + + +A P
Sbjct: 1220 ASVPTSEEPASL--AAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTP 1277
Query: 873 EGPASPGS 880
E PASP +
Sbjct: 1278 EEPASPAA 1285
Score = 51.6 bits (122), Expect = 3e-06
Identities = 53/187 (28%), Positives = 74/187 (39%), Gaps = 14/187 (7%)
Query: 697 PLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVS-GEEELHTGP----PAPQGPLSVPQG 751
P S + P P P+ A P P + PTSP + E T P P P+ P S
Sbjct: 1000 PASPAAAVPTPEEPTSPAAAVPTPEE-PTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAA 1058
Query: 752 LPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGI 811
+PT + PA A ++PT P+A E EP++P A+ + + + +
Sbjct: 1059 VPTPEEPTSPA--AAVPTPEEPTSPAAAVPTPE-----EPTSPAAAVPTPEEPTSPAAAV 1111
Query: 812 RSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSA 871
+ + A P+ PAS A P T E P P +SA A P P SA
Sbjct: 1112 PTPEEPASPAAAVPTPEEPASPAAAVP-TPEEPAFPAPAVPTPEESASAAVAVPTPEESA 1170
Query: 872 PEGPASP 878
A P
Sbjct: 1171 SPAAAVP 1177
Score = 43.1 bits (100), Expect = 0.001
Identities = 47/184 (25%), Positives = 72/184 (39%), Gaps = 20/184 (10%)
Query: 707 PPGPSWTATFDPVPTDAPTSP-RVSGEEELHT---GPPAPQGPLSVPQGLPTQSLASPPA 762
P GP AT P + T+ RVS EE + P P+ P S +PT + PA
Sbjct: 971 PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030
Query: 763 RDALQLRSQDPTPPSA----PQEATEGSKVT----EPSAPCQALVSIGDLQATFHGIRSA 814
A ++PT P+A P+E T + EP++P A+ + + + + +
Sbjct: 1031 --AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1088
Query: 815 PSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEG 874
+ A P+ P S A P E + P+ ++ A P PE
Sbjct: 1089 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP------TPEE 1142
Query: 875 PASP 878
PA P
Sbjct: 1143 PAFP 1146
Score = 40.4 bits (93), Expect = 0.007
Identities = 43/188 (22%), Positives = 74/188 (39%), Gaps = 24/188 (12%)
Query: 690 AARGGATPLSYPSPGPQPPGPSWTATFDPVPT--DAPTSPRVSGEEELHTGPPAPQGPLS 747
AA TP SP P P+ +A+F V + PTSP S P P ++
Sbjct: 1159 AAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAAS--------VPTPAAMVA 1210
Query: 748 VPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQAT 807
+ + + + P + + L + P A + EP++ A+++ +L
Sbjct: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEEL--- 1267
Query: 808 FHGIRSAPSSSDSATRDPSTSVPA-SGAHQPPQTTEGEKSPEPLGLPQSQSAQALTP--P 864
S+P++S +P++ A S +P +PE +P +A TP P
Sbjct: 1268 -----SSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIP---AASVPTPEVP 1319
Query: 865 PIPNGSAP 872
IP + P
Sbjct: 1320 AIPAAAVP 1327
Score = 40.0 bits (92), Expect = 0.010
Identities = 46/183 (25%), Positives = 74/183 (40%), Gaps = 19/183 (10%)
Query: 697 PLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVS-GEEELHTGP----PAPQGPLSVPQG 751
P S + P P P+ A P P + PTSP + E T P P P+ P S
Sbjct: 1026 PTSPAAAVPPPEEPTSPAAAVPTPEE-PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1084
Query: 752 LPTQSLASPPARDALQLRSQDPTPPSA----PQEATEGSKVT----EPSAPCQALVSIGD 803
+PT + PA A ++PT P+A P+E + EP++P A+ + +
Sbjct: 1085 VPTPEEPTSPA--AAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEE 1142
Query: 804 LQATFHGIRSAPSSSDSATRDPS---TSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQA 860
+ + S+ +A P+ ++ PA+ P ++ L P S +A
Sbjct: 1143 PAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASV 1202
Query: 861 LTP 863
TP
Sbjct: 1203 PTP 1205
Score = 37.4 bits (85), Expect = 0.062
Identities = 38/178 (21%), Positives = 61/178 (34%), Gaps = 15/178 (8%)
Query: 710 PSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLR 769
P W A VP ++ E+ GP P + P+ T ++ +
Sbjct: 953 PEWAALAITVP--------ITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPA 1004
Query: 770 SQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSV 829
+ PTP A EP++P A+ + + + + + A P+
Sbjct: 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1064
Query: 830 PASGAHQPPQTTEGEKSPEPLGLPQ--SQSAQALTPPPIPNGSA-----PEGPASPGS 880
P S A P E + P+ + A A+ P P A PE PASP +
Sbjct: 1065 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA 1122
Score = 35.8 bits (81), Expect = 0.18
Identities = 36/153 (23%), Positives = 61/153 (39%), Gaps = 12/153 (7%)
Query: 702 SPGPQPPGPS-WTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASP 760
SP P P+ AT + + A + P L P+ P S +PT L P
Sbjct: 1197 SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPT--LEEP 1254
Query: 761 PARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDS 820
+ A L ++ + P+A E EP++P A+ ++ + + + + ++
Sbjct: 1255 TSSAAAVLTPEELSSPAASVPTPE-----EPASPAAAVSNLEEPASPAAAVPTPEVAAIP 1309
Query: 821 ATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLP 853
A P+ VPA A P E P+G+P
Sbjct: 1310 AASVPTPEVPAIPAAAVPPMEE----VSPIGVP 1338
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 55.5 bits (132), Expect = 2e-07
Identities = 56/187 (29%), Positives = 78/187 (41%), Gaps = 22/187 (11%)
Query: 695 ATPLSYPSPGPQP-PGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLP 753
+T P+P P P P P+ T T P APT S + L G PQGP P
Sbjct: 1659 STQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGP------FP 1712
Query: 754 TQSLASPPARDAL----QLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFH 809
TQ+L+ PA + Q S P PP P + P+ P +G A H
Sbjct: 1713 TQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLS----LAPAPPLAPASPVGPAPA--H 1766
Query: 810 GIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGL----PQSQSAQALTPPP 865
+ AP+SS ++ P+ SV P T G + + L L QS ++QA +
Sbjct: 1767 TLTLAPASSSASLLAPA-SVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVV 1825
Query: 866 IPNGSAP 872
+G+AP
Sbjct: 1826 SASGAAP 1832
Score = 51.2 bits (121), Expect = 4e-06
Identities = 57/208 (27%), Positives = 80/208 (38%), Gaps = 29/208 (13%)
Query: 690 AARGGATPLSYPSPGPQP---PGPSWTATFDPVPTDAPTSPRVSGEEELH---------- 736
A+ GA PL+ SP P PGP+ + P+P +P + VS +
Sbjct: 1387 ASAPGAAPLTISSPLHVPSSLPGPASSPM--PIPNSSPLASPVSSTVSVPLSSSLPISVP 1444
Query: 737 TGPPAP-QGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPC 795
T PAP PL++P P AS PA P P+AP + PSA
Sbjct: 1445 TTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASA 1504
Query: 796 QALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQS 855
L G+ +APS S S T + + +H P + + P+ +P S
Sbjct: 1505 LTL-----------GLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPAS 1553
Query: 856 QSAQAL--TPPPIPNGSAPEGPASPGSQ 881
A P P P ++ PAS SQ
Sbjct: 1554 ALASPFPSAPNPAPAQASLLAPASSASQ 1581
Score = 45.1 bits (105), Expect = 3e-04
Identities = 43/206 (20%), Positives = 82/206 (39%), Gaps = 30/206 (14%)
Query: 487 LRQLLKELPSEQQEQWEAFVSGPLAETNKKNMVDLVNTHHLHSSSDDEDDRLKEFNFPEE 546
L +LL+ LP + E GP + + + D +++E ++ E P
Sbjct: 332 LEELLRSLPPQLLE-------GPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPS 384
Query: 547 AVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTANITFSLNADDENPNA 606
AV Q+ + + F N+EE ++E+++ A + ++ + A
Sbjct: 385 AVTQRNKQPWHPDEDD----EEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSEL---A 437
Query: 607 NLLEICYKDRIQQF-------DDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQP 659
E+ ++ +QQ+ E+EDE+E + +G + + P
Sbjct: 438 REGELSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEE---------P 488
Query: 660 PGVRSGGSTDSEDEEEEDEEEEEDEE 685
P S +DS ++ EDEE+E EE
Sbjct: 489 PQEDSSSQSDSVEDRSEDEEDEHSEE 514
Score = 44.3 bits (103), Expect = 5e-04
Identities = 46/241 (19%), Positives = 94/241 (39%), Gaps = 40/241 (16%)
Query: 479 EKGPNAEQLRQLLKELPSEQQEQWEAFVSGPLAETNKKNMVDLVNTHHLHSSSDDEDDRL 538
E+ P +++ + ++ W N++ D +T + E D
Sbjct: 371 EEPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHA 430
Query: 539 KEFNFPEEAVLQQAFMDFQMQRMTSAFIDHFGFNDEEFGEQEESVNAPFDKTANITFSLN 598
E + E A + M+ +Q+ A+ G +++E ++ ++ ++ + +
Sbjct: 431 MELS--ELAREGELSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEP 488
Query: 599 ADDENPNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQ 658
+++ + + D ++ +DEE+E EE + SG S E+
Sbjct: 489 PQEDSSSQS-------DSVEDRSEDEEDEHSEEEETSGSSASEES--------------- 526
Query: 659 PPGVRSGGSTDSEDEEEEDEEEEEDEEGI---------GCAARGGATPLSYPSPGPQPPG 709
S S D++ + + DEEEE+D+ G+ A G+ P P+PGP G
Sbjct: 527 ----ESEESEDAQSQSQADEEEEDDDFGVEYLLARDEEQSEADAGSGP---PTPGPTTLG 579
Query: 710 P 710
P
Sbjct: 580 P 580
Score = 43.5 bits (101), Expect = 9e-04
Identities = 59/225 (26%), Positives = 77/225 (34%), Gaps = 39/225 (17%)
Query: 690 AARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAP------------------------- 724
A R G TP+ +P P+PP A +P PT P
Sbjct: 1316 APRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLL 1375
Query: 725 -----TSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAP 779
SP VS P PL VP LP + + P ++ L S + S P
Sbjct: 1376 KLVHSPSPEVSASAP-GAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVP 1434
Query: 780 QEATEGSKV-TEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPP 838
++ V T AP A ++I + A S P+ S T + VPA A PP
Sbjct: 1435 LSSSLPISVPTTLPAPASAPLTI-PISAPLTVSASGPALLTSVTPPLAPVVPA--APGPP 1491
Query: 839 QTTEGEKSPE----PLGLPQSQSAQALTPPPIPNGSAPEGPASPG 879
SP LGL + S + P P AP PG
Sbjct: 1492 SLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPG 1536
Score = 41.6 bits (96), Expect = 0.003
Identities = 50/196 (25%), Positives = 73/196 (37%), Gaps = 24/196 (12%)
Query: 695 ATPLSYPSPGPQPPGPSWTATFDPVPTDA-----PTSPRVSGEEELHTGPPAPQGPLSVP 749
A+ L+ P P P P+ + P + + P +P + + + PAP PL+
Sbjct: 1552 ASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAP--PLA-- 1607
Query: 750 QGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPS---APCQALVSIGD--- 803
P LA P + SQ P P AP +T G+ + S AP L
Sbjct: 1608 ---PLPVLAPSPGAAPVLASSQTPVPVMAP-SSTPGTSLASASPVPAPTPVLAPSSTQTM 1663
Query: 804 LQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQT----TEGEKSPEPLGLPQSQSAQ 859
L A +P+S+ + P+ + P G P QT T + P P A
Sbjct: 1664 LPAPVPSPLPSPASTQTLALAPALA-PTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPAS 1722
Query: 860 ALTPPPIPNGSAPEGP 875
+L P P S GP
Sbjct: 1723 SLVPTPAQTLSLAPGP 1738
Score = 41.6 bits (96), Expect = 0.003
Identities = 40/144 (27%), Positives = 53/144 (36%), Gaps = 10/144 (6%)
Query: 747 SVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQA 806
S P P Q+ PA A Q + P +APQ A P AP L
Sbjct: 1561 SAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAP 1620
Query: 807 TFHGIRS-----APSSSDSATRDPSTSVPASGAHQPPQTTE---GEKSPEPLGLPQSQSA 858
++ APSS+ + ++ VPA P +T+ P PL P S
Sbjct: 1621 VLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQT 1680
Query: 859 QALTP--PPIPNGSAPEGPASPGS 880
AL P P GS+P S G+
Sbjct: 1681 LALAPALAPTLGGSSPSQTLSLGT 1704
Score = 38.5 bits (88), Expect = 0.028
Identities = 72/345 (20%), Positives = 125/345 (36%), Gaps = 59/345 (17%)
Query: 550 QQAFMDFQMQRMTSAFIDHFGFNDEEFGEQ-EESVNAPFDKTAN-----ITFSLNADDEN 603
QQ+ ++ + ++ +D E++ + +S+N P + + S A
Sbjct: 217 QQSRLEEKRKKALDLHLDFIVGQTEKYSDLLSQSLNQPLTSSKAGSSPCLGSSSAASSPP 276
Query: 604 PNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQ----- 658
P A+ L+ +D Q +DEEE+DEE + + +G D Q ++ R G+
Sbjct: 277 PPASRLDD--EDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEE 334
Query: 659 -----PPGVRSGGSTDSE-----DEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPP 708
PP + G S+ S+ D + D EE EE P + QP
Sbjct: 335 LLRSLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPW 394
Query: 709 GP-----SWTATFDPVPTDAPT---SPRVSGEEE--LHTGPPAPQGPLSVPQGLPTQSLA 758
P +TA + + T ++ GE + + A +G LS+ + L + A
Sbjct: 395 HPDEDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGA 454
Query: 759 SPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSS 818
P + + +D E S EP P +A P
Sbjct: 455 YAPGSGSSEDEDED--------EVDANSSDCEPEGPVEA---------------EEPPQE 491
Query: 819 DSATRDPST---SVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQA 860
DS+++ S S H + T G + E +S+ AQ+
Sbjct: 492 DSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQS 536
Score = 36.6 bits (83), Expect = 0.11
Identities = 63/280 (22%), Positives = 91/280 (32%), Gaps = 39/280 (13%)
Query: 627 EDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVR-----SGGSTDSEDEEEEDEEEE 681
++EEE G+G+ + ++ A+ + PG R G +++
Sbjct: 2358 QEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISA 2417
Query: 682 EDEEGIGCAARGGATPLSYPSPGPQP-----PGPSWTATFDPVPTDAPT-----SPRVSG 731
R P P P+P P+ PVP AP +P
Sbjct: 2418 HQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITIL 2477
Query: 732 EEELHTGPPAPQG--PLSVPQGLPTQSLASPPARDALQLRSQDPTPPS----APQEATEG 785
+ PP P P S P P + PPA ++ TP S P
Sbjct: 2478 PVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPIS 2537
Query: 786 SKVT--------EPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQP 837
+ VT E QAL S L+ + S+ +SS S P +P + P
Sbjct: 2538 ASVTNLPLGLRPEAELCAQALASPESLELA--SVASSETSSLSLV-PPKDLLPVAVEILP 2594
Query: 838 PQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPAS 877
S + L L S + L IPNG E P S
Sbjct: 2595 V-------SEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDS 2627
Score = 35.4 bits (80), Expect = 0.23
Identities = 63/235 (26%), Positives = 84/235 (35%), Gaps = 67/235 (28%)
Query: 697 PLSYPSPG--------PQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQ----- 743
P+S P+P P PP PS P + A T P HT PPA
Sbjct: 2467 PISAPNPITILPVHILPSPPPPS---QIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTP 2523
Query: 744 ------GPLSVP-----QGLP----------TQSLASPPARDALQLRSQDPT------PP 776
GP SVP LP Q+LASP + + + S + + P
Sbjct: 2524 SSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPK 2583
Query: 777 SAPQEATEGSKVTE------PSAPCQALV--SIGDLQATFHGIRSAPSSSDSATRD---- 824
A E V+E PSAP L SI + Q + AP S++ T
Sbjct: 2584 DLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQE-----QEAPDSAEGTTLTVLPE 2638
Query: 825 ----PSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGP 875
P ++G PP E EP L ++++ LT P S+PE P
Sbjct: 2639 GEELPLCVSESNGLELPPSAASDEPLQEP--LEADRTSEELTEAKTPT-SSPEKP 2690
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 55.1 bits (131), Expect = 3e-07
Identities = 65/291 (22%), Positives = 99/291 (34%), Gaps = 48/291 (16%)
Query: 596 SLNADDENPNANLLEICYKDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGAR 655
++N+ DE E ++ ++ ++D EEE+E+E + E + E+ ++
Sbjct: 882 NINSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941
Query: 656 LGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPG---PSW 712
L + + E+E+EE+EEE E+ E + GG P P PP P
Sbjct: 942 LEE----------EEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPES 991
Query: 713 TATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQD 772
P P P E A P P+ LP+Q ++ +
Sbjct: 992 PPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQG--------EVEREGES 1043
Query: 773 PTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPAS 832
P PQE E EPSAP P+ + T D S V
Sbjct: 1044 PAAGPPPQELVE----EEPSAP--------------------PTLLEEETEDGSDKVQPP 1079
Query: 833 GAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPI---PNGSAPEGPASPGS 880
+ E E E L + A+ I P+ P P P S
Sbjct: 1080 PETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPDS 1130
Score = 46.6 bits (109), Expect = 1e-04
Identities = 54/214 (25%), Positives = 84/214 (39%), Gaps = 27/214 (12%)
Query: 573 DEEFGEQEESVNAPFDKTANITFSLNADDENPNANLLEICYKDRIQQFDDDEEEEDEEEA 632
+E+F E+EE F ++E E +++ + +++EEEEDEEE
Sbjct: 907 EEDFEEEEEDEEEYF------------EEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEE 954
Query: 633 QGSGESDGEDGAWQGSQLARGARLGQ--PPGVRSGGSTDSEDEEEEDE-------EEEED 683
+ E + + G ++ GA PP + S E E E EE
Sbjct: 955 EELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGT 1014
Query: 684 EEGIGCAARGGATPLSYPSPGP-QPPGPSWTATFDP--VPTDAPTSPRVSGEEELHTGPP 740
EE G P + PS G + G S A P + + P++P EEE G
Sbjct: 1015 EEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSD 1074
Query: 741 APQGPLSVPQGLPTQSLASPPARDALQLRSQDPT 774
Q P P+ + + + +ALQ + QD T
Sbjct: 1075 KVQPP---PETPAEEEMETETEAEALQEKEQDDT 1105
Score = 40.0 bits (92), Expect = 0.010
Identities = 55/216 (25%), Positives = 68/216 (31%), Gaps = 49/216 (22%)
Query: 693 GGATPLSYPSPGPQPPGPSWTATFDP---------VPTDAP-----TSPRVSGEEELHTG 738
G P P P P+ P P F P +P+ P P G
Sbjct: 642 GPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPG 701
Query: 739 PPAPQGPLSVPQGLPTQSLASPPAR--------------DALQLRSQDPTPPSAPQEATE 784
PP L GL L S P R D + S P PP+ P + T
Sbjct: 702 PPTTANHL----GLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTP-PPTIPPDETF 756
Query: 785 GSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGE 844
G +V P A V +A+ I S DS P P PP G
Sbjct: 757 GGRVPRP-----AFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL-----PPPPPSGA 806
Query: 845 KSPEPLGLPQSQSAQALTPPPIPNGSAPEG-PASPG 879
P P + + PP+P PE PA+PG
Sbjct: 807 TPP-----PIAPTGPPTASPPVPAKEEPEELPAAPG 837
Score = 37.0 bits (84), Expect = 0.081
Identities = 51/205 (24%), Positives = 71/205 (34%), Gaps = 33/205 (16%)
Query: 699 SYPSPGPQPP-GPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGL--PTQ 755
S PS GP P GP +A PVP+ P P + H G P G +SVP L +
Sbjct: 676 SMPSAGPMPSAGPMPSA--GPVPSARPGPPTTAN----HLGLSVP-GLVSVPPRLLPGPE 728
Query: 756 SLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFH------ 809
+ + D + S P PP+ P + T G +V P+ D++ +
Sbjct: 729 NHRAGSNEDPILAPSGTP-PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDS 787
Query: 810 ------GIRSAPSSSDSA--------TRDPSTSVPASGAHQPPQ--TTEGEKSPEPLGLP 853
G+ P S T P+ S P +P + G P P P
Sbjct: 788 VVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPP 847
Query: 854 QSQSAQALTPPPIPNGSAPEGPASP 878
L PP + P G P
Sbjct: 848 PVPGPVTLPPPQLVPEGTPGGGGPP 872
Score = 36.6 bits (83), Expect = 0.11
Identities = 43/130 (33%), Positives = 50/130 (38%), Gaps = 16/130 (12%)
Query: 659 PPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSP-GPQPPGPSWTATFD 717
PP GG D+EE D E I + + + P P PP P AT
Sbjct: 751 PPDETFGGRVPRPAFVHYDKEEASDVE-ISLESDSDDSVVIVPEGLPPLPPPPPSGATPP 809
Query: 718 PV-PTDAPT-SPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTP 775
P+ PT PT SP V +EE P AP GPL P P PP + L P
Sbjct: 810 PIAPTGPPTASPPVPAKEEPEELPAAP-GPLPPPPPPP------PPVPGPVTL-----PP 857
Query: 776 PSAPQEATEG 785
P E T G
Sbjct: 858 PQLVPEGTPG 867
Score = 34.7 bits (78), Expect = 0.40
Identities = 17/35 (48%), Positives = 22/35 (62%), Gaps = 6/35 (17%)
Query: 657 GQPPGVRSG------GSTDSEDEEEEDEEEEEDEE 685
G PP + S+D E+EEEE+EEEEE+EE
Sbjct: 869 GGPPALEEDLTVININSSDEEEEEEEEEEEEEEEE 903
Score = 32.3 bits (72), Expect = 2.0
Identities = 13/24 (54%), Positives = 18/24 (75%)
Query: 662 VRSGGSTDSEDEEEEDEEEEEDEE 685
+ S + E+EEEE+EEEEE+EE
Sbjct: 881 ININSSDEEEEEEEEEEEEEEEEE 904
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 53.5 bits (127), Expect = 8e-07
Identities = 54/179 (30%), Positives = 70/179 (39%), Gaps = 24/179 (13%)
Query: 702 SPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPP 761
+P PP P A F P P P SP + + AP PL VP P ASPP
Sbjct: 438 APFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAP--PLQVPPSPP----ASPP 490
Query: 762 ARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSS-SDS 820
S P P + P A ++ +P ++ LQA + S P+S
Sbjct: 491 MSP-----SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA----LPSPPASFPGQ 541
Query: 821 ATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPG 879
A PS S+P S PP ++P L P Q + PP P AP P +PG
Sbjct: 542 APFSPSASLPMSPLATPPP-----QAPPVLAAPLLQVPPS--PPASPTLQAPRRPPTPG 593
Score = 52.0 bits (123), Expect = 2e-06
Identities = 55/194 (28%), Positives = 74/194 (38%), Gaps = 24/194 (12%)
Query: 695 ATPLSYPSPGPQPPGPSWTATFDPV--PTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGL 752
ATPL P P P T P P+ A TS + H+ P+P
Sbjct: 335 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP---------- 384
Query: 753 PTQSLASPPARD----ALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATF 808
P LA+PP + AL P+PP++P S + PS +++ LQA F
Sbjct: 385 PLSPLATPPPQAPPALALPPLQAPPSPPASPPL----SPLATPSPQAPNALAVHLLQAPF 440
Query: 809 HGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQ-ALTPPPIP 867
PS A P S P S + PP + PL +P S A ++P P
Sbjct: 441 ---SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497
Query: 868 NGSAPEGPASPGSQ 881
AP A+P Q
Sbjct: 498 PPQAPPPLAAPPLQ 511
Score = 46.2 bits (108), Expect = 1e-04
Identities = 60/224 (26%), Positives = 79/224 (35%), Gaps = 54/224 (24%)
Query: 688 GCAARGGATPLSYPS------------PGPQPPGPSWTATFDPVPTDAPTSPRVSGEEEL 735
G +ARG ++PS P PP P+ + +P S +
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS 315
Query: 736 HTGPPAPQGP--------LSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSK 787
P P P L+ P L S ++PP+ L P+PP+ P
Sbjct: 316 QAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL------PSPPATP-------- 361
Query: 788 VTEPSAPCQALVSIGD--LQATFHGIRSAPSSSDSATRDP-STSVPASGAHQPPQTTEGE 844
P QA S+G LQAT H +P S AT P + A Q P +
Sbjct: 362 ------PSQATTSLGSPTLQAT-HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414
Query: 845 KSPEPLGLPQSQSAQAL---------TPPPIPNGSAP-EGPASP 878
PL P Q+ AL +PPP P AP PASP
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458
Score = 42.0 bits (97), Expect = 0.003
Identities = 54/194 (27%), Positives = 65/194 (33%), Gaps = 23/194 (11%)
Query: 697 PLSYPSPGPQ-PPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGP--LSVPQGLP 753
P S +P Q PP P + P T P +P L P PQ P L+ P P
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP---P 527
Query: 754 TQSLASPPA----------RDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGD 803
Q+L SPPA +L + PP AP PS P
Sbjct: 528 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP-----T 582
Query: 804 LQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTP 863
LQA P +S S R T A G PP + P S SA +
Sbjct: 583 LQAPRRPPTPGPDTSVSGPR--LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 640
Query: 864 PPIPNGSAPEGPAS 877
S PEG A+
Sbjct: 641 ELRGYDSGPEGGAA 654
Score = 41.2 bits (95), Expect = 0.004
Identities = 52/213 (24%), Positives = 72/213 (33%), Gaps = 51/213 (23%)
Query: 695 ATPLSYPSPGPQPPGPSWTATFDPVP-------------------TDAPTSPRVSGEEEL 735
A P SPGP + T P P T+AP +S
Sbjct: 103 APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 162
Query: 736 HTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSK-------- 787
T P P G P+ ++A ++ P P + P+ TEG +
Sbjct: 163 DTSGPTP--------GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214
Query: 788 --VTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASG--AHQPPQTTEG 843
TEPS + S G G++ S S S++ P +S SG A P+
Sbjct: 215 HSTTEPSPAARRRPSAGG------GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 844 EKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPA 876
P+P GL QAL PP + PA
Sbjct: 269 PSQPKPKGL------QALRPPQVTPPRKDAAPA 295
Score = 39.7 bits (91), Expect = 0.012
Identities = 51/189 (26%), Positives = 65/189 (34%), Gaps = 27/189 (14%)
Query: 703 PGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGP-LSVPQGLPT----QSL 757
PG P PS + P+ T P +P V L P P P L P+ PT S+
Sbjct: 539 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 598
Query: 758 ASPPARDALQLRSQDPTPPS-APQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPS 816
+ P R L L P PPS +P G + S+ S G S P
Sbjct: 599 SGP--RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS------SATSTPEELRGYDSGPE 650
Query: 817 SSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSA----- 871
+A+ P + A P + G PL + A PP GSA
Sbjct: 651 GGAAASPPPDAELAAC---HPAAWSRG--PAPPLAFRGAPGAPLPWPPATGPGSADGLCT 705
Query: 872 ---PEGPAS 877
EGP S
Sbjct: 706 IYETEGPES 714
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 53.1 bits (126), Expect = 1e-06
Identities = 64/281 (22%), Positives = 106/281 (37%), Gaps = 35/281 (12%)
Query: 625 EEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGSTD--SEDEEEEDEEEEE 682
+ + E A + A S A G G+ + G T S + + +
Sbjct: 784 QTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQS 843
Query: 683 DEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAP 742
E + +A GA P+S PG TF P ++A T+ R +G+ + +P
Sbjct: 844 TTELLSASASHGAIPVSTGMASSIVPG-----TFHPTLSEASTAGRPTGQSSPTSPSASP 898
Query: 743 QGPLSVPQGLPTQSLASPPARDALQLRSQ--------DPTPPS-------APQEAT---- 783
Q ++ + TQ + D + L SQ PTPPS +PQ T
Sbjct: 899 QETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLS 958
Query: 784 -EGSKVTEPSA----PCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPP 838
GS T +A V+ +T H + + S + +T +P + P
Sbjct: 959 PSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVT---SPS 1015
Query: 839 QTTEGEKSPEPLGLPQSQSAQALTPPPIPN-GSAPEGPASP 878
+ G +P P+ S+S +TP P+ + SA G ++P
Sbjct: 1016 SVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTP 1056
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/168 (24%), Positives = 67/168 (39%), Gaps = 20/168 (11%)
Query: 713 TATFDPVPTDAPTSPRVSGEEELH-TGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQ 771
T P+P + +S LH T P + + P LP SL+S D +
Sbjct: 1483 TGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATP--LPVTSLSSASTGDTM----- 1535
Query: 772 DPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPA 831
P P ++P A+ G P ++ +T H +S SA+ +T +P
Sbjct: 1536 -PLPVTSPSSASTGDTTPLPVTDASSV-------STGHTTPLPVTSPSSASTGHTTPLPV 1587
Query: 832 SGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPN-GSAPEGPASP 878
+ ++G+ +P P+ P S S TP P+ + SA G +P
Sbjct: 1588 TDTSS---ASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGDTTP 1632
Score = 37.7 bits (86), Expect = 0.047
Identities = 51/208 (24%), Positives = 76/208 (36%), Gaps = 27/208 (12%)
Query: 690 AARGGATPLSYPSPGPQPPG---PSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPL 746
A+ G ATPL SP G P T T V+ TG P P+
Sbjct: 2201 ASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPL-PV 2259
Query: 747 SVPQGLPTQSLASPPARDALQLRSQD--PTPPSAPQEATEGSKVTEPSAPCQALVSIGDL 804
+ + T S P + + D P P ++P A+ G + P V+
Sbjct: 2260 TDASSVSTGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGH-----ATPLH--VTDASS 2312
Query: 805 QATFHGIRSAPSSSDSATRDPSTSVP------ASGAHQPP-------QTTEGEKSPEPLG 851
+T H +S SA+ +T +P AS H P + G+ +P P+
Sbjct: 2313 ASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTPLPVT 2372
Query: 852 LPQSQSAQALTPPPIPN-GSAPEGPASP 878
S S+ TP P+ + SA G +P
Sbjct: 2373 SSSSASSGHTTPLPVTDASSASTGDTTP 2400
Score = 36.2 bits (82), Expect = 0.14
Identities = 57/222 (25%), Positives = 80/222 (36%), Gaps = 41/222 (18%)
Query: 690 AARGGATPLSYPSPGPQPPGPSWTATFDPVP--------TDAPTSPRVSGEEELHTGPPA 741
A+ G ATPL TA P+P TD T V+ TG
Sbjct: 1753 ASTGQATPLPVTDTSSVS-----TAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAI 1807
Query: 742 PQGPLSVPQGLPTQSLASPPARDALQLRSQDPT--PPSAPQEATEGSKVTEPSAPCQALV 799
P P++ P T P DA + D T P + P A+ G + P + V
Sbjct: 1808 PL-PVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASS-V 1865
Query: 800 SIGDLQATFHGIRSAPSSSDSA------TRDPST------------SVPASGAHQPPQTT 841
S G + S+ S+ D+ T ST SV A P T+
Sbjct: 1866 STGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTS 1925
Query: 842 -----EGEKSPEPLGLPQSQSAQALTPPPIPNGSA-PEGPAS 877
G+ +P P+ P S S+ TP P+ + S+ P G A+
Sbjct: 1926 LSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHAT 1967
Score = 36.2 bits (82), Expect = 0.14
Identities = 42/190 (22%), Positives = 70/190 (36%), Gaps = 16/190 (8%)
Query: 687 IGCAARGGATPL-----SYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPA 741
+ + G TPL S S G P P + V T T V+ + TG
Sbjct: 3414 LSSVSTGDTTPLPVTDASSASTGQATPLP--VTSLSSVSTGDTTPLLVTDASSVSTGHAT 3471
Query: 742 PQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSI 801
P P++ T P D + TP ++ + T P LV+
Sbjct: 3472 PL-PVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTP-----LLVTD 3525
Query: 802 GDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQAL 861
+T H + + SA+ +T +P + + G+ +P P+ +P S S+
Sbjct: 3526 ASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSS---ASTGQATPLPVTIPSSSSSGHT 3582
Query: 862 TPPPIPNGSA 871
TP P+ + S+
Sbjct: 3583 TPLPVTSTSS 3592
Score = 34.7 bits (78), Expect = 0.40
Identities = 55/230 (23%), Positives = 79/230 (34%), Gaps = 48/230 (20%)
Query: 687 IGCAARGGATPLSYPSPGPQPPG---PSWTATFDPVPTDAPTSPRVSGEEELHTGPPAP- 742
+ A+ G TPL SP G P VPT TS V+ + TG P
Sbjct: 1926 LSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPL 1985
Query: 743 ------------QGPL------SVPQG----LPTQSLASPPARDALQLRSQDPTPPSAPQ 780
PL SV G LP SL+S D L D + S Q
Sbjct: 1986 PVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQ 2045
Query: 781 EA--------------TEGSKVTEPSAPCQA-----LVSIGDLQATFHGIRSAPSSSDSA 821
+ T VT PS+ LV+ +T H + + S
Sbjct: 2046 DTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSV 2105
Query: 822 TRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSA 871
+ +T++ + A + G+ +P P+ P S S TP P+ + S+
Sbjct: 2106 STGHATALHVTDASS---LSTGDTTPLPVTSPSSASTGDTTPLPVTDTSS 2152
Score = 34.7 bits (78), Expect = 0.40
Identities = 45/187 (24%), Positives = 64/187 (34%), Gaps = 23/187 (12%)
Query: 693 GGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGL 752
G TPL SP G P+P + +S H P SV G
Sbjct: 3596 GHVTPLHVTSPSSASTGH-----VTPLPVTSTSSASTG-----HATPLLVTDASSVSTGH 3645
Query: 753 PTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIR 812
T P DA + D TP ++ + P P +L S+ T +
Sbjct: 3646 ATPL----PVTDASSASTGDTTPLPVTDTSSASTGQATP-LPVTSLSSVSTGDTTPLPVT 3700
Query: 813 SAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPN-GSA 871
A S+S ++P+S + G+ P P+ P S S TP P+ SA
Sbjct: 3701 DASSASTGHATPLPVTIPSS-------VSTGDTMPLPVTSPSSASTGHATPLPVTGLSSA 3753
Query: 872 PEGPASP 878
G +P
Sbjct: 3754 STGDTTP 3760
Score = 34.7 bits (78), Expect = 0.40
Identities = 45/195 (23%), Positives = 70/195 (35%), Gaps = 16/195 (8%)
Query: 690 AARGGATPL-----SYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQG 744
A+ G ATPL S S G P P + V T T V+ TG P
Sbjct: 3849 ASTGHATPLPVTDTSSVSTGHATPLP--VTSTSSVSTGHATPLPVTSPSSASTGHATPV- 3905
Query: 745 PLSVPQGLPTQSLASPPARDALQLRSQDPTP--PSAPQEATEGSKVTEPSAPCQALVSIG 802
P++ T P +A L + TP ++P A+ G T P + +
Sbjct: 3906 PVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGH 3965
Query: 803 DLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTE------GEKSPEPLGLPQSQ 856
+ S + + TS ++G P T G+ +P P+ +P S
Sbjct: 3966 ATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSA 4025
Query: 857 SAQALTPPPIPNGSA 871
S+ T P+ + S+
Sbjct: 4026 SSGHTTSLPVTDASS 4040
Score = 34.3 bits (77), Expect = 0.52
Identities = 44/199 (22%), Positives = 70/199 (35%), Gaps = 17/199 (8%)
Query: 686 GIGCAARGGATPLSYP---SPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAP 742
G+ A+ G TPL S + P TD T V+ TG P
Sbjct: 3749 GLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATP 3808
Query: 743 QGPLSVPQGLPTQSLASPPARDALQLRSQDPT--PPSAPQEATEGSKVTEPSAPCQALVS 800
P++ T P D + + T P ++ A+ G P ++
Sbjct: 3809 L-PVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSV-- 3865
Query: 801 IGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQA 860
+T H +S+ S + +T +P + P + G +P P+ S S
Sbjct: 3866 -----STGHATPLPVTSTSSVSTGHATPLPVTS---PSSASTGHATPVPVTSTSSASTGD 3917
Query: 861 LTPPPIPNGSA-PEGPASP 878
TP P+ N S+ G A+P
Sbjct: 3918 TTPLPVTNASSLSTGHATP 3936
Score = 33.9 bits (76), Expect = 0.68
Identities = 54/222 (24%), Positives = 83/222 (37%), Gaps = 33/222 (14%)
Query: 687 IGCAARGGATPL-----SYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPA 741
+ A+ G ATPL S S G P P + V T T V+ + TG
Sbjct: 2438 VSSASTGHATPLPVTSTSSASTGDTTPLPGTDTS--SVSTGHTTPLLVTDASSVSTGDTT 2495
Query: 742 PQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSK------VTEPSAPC 795
+ P++ P T P D + D TP ++ ++ VT PS+
Sbjct: 2496 -RLPVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSAS 2554
Query: 796 QALVS---IGDLQA--TFHGIRSAPSSSDSATRDPSTSVP-------ASGAHQPPQTTE- 842
+ + D A T H +S+ SA+ +T +P ++G P T+
Sbjct: 2555 TGHATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDT 2614
Query: 843 -----GEKSPEPLGLPQSQSAQALTPPPIPN-GSAPEGPASP 878
G+ +P P+ S S TP P+ N S G A+P
Sbjct: 2615 SSASTGDTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATP 2656
Score = 32.3 bits (72), Expect = 2.0
Identities = 46/187 (24%), Positives = 67/187 (35%), Gaps = 32/187 (17%)
Query: 690 AARGGATPL-----SYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQG 744
A+ G ATPL S S G P P A+ V TD TS V+ TG P
Sbjct: 1193 ASTGHATPLLVTDTSSASTGHATPLPVTDAS--SVSTDHATSLPVTIPSAASTGHTTPL- 1249
Query: 745 PLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDL 804
P++ T S D + + D TP ++ + P
Sbjct: 1250 PVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTP------------- 1296
Query: 805 QATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPP 864
H + +S+ AT P TS+ ++ G+ P P+ P S S TP
Sbjct: 1297 ---LHVTSPSSASTGHATPLPVTSLSSAST--------GDTMPLPVTSPSSASTGDTTPL 1345
Query: 865 PIPNGSA 871
P+ + S+
Sbjct: 1346 PVTDASS 1352
Score = 30.0 bits (66), Expect = 9.9
Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 11/115 (9%)
Query: 773 PTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPAS 832
P ++P A+ G P ++ + G+ SA S+ TR P T + ++
Sbjct: 3200 PLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSA--STGDTTRLPVTDISSA 3257
Query: 833 GAHQPP--------QTTEGEKSPEPLGLPQSQSAQALTPPPIPN-GSAPEGPASP 878
Q + G+ P P+ P S S TP P+ + SA G A+P
Sbjct: 3258 STGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATP 3312
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 53.1 bits (126), Expect = 1e-06
Identities = 57/201 (28%), Positives = 74/201 (36%), Gaps = 27/201 (13%)
Query: 696 TPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQ 755
+PLS P P P P+ P P +P SP EE PP + P S P P
Sbjct: 518 SPLSPPEESP--PSPALETPLSPPPEASPLSPPF---EESPLSPPPEELPTSPP---PEA 569
Query: 756 SLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAP 815
S SPP ++ + +P S P EA+ E S P L R +P
Sbjct: 570 SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEES-PLSPPPEESPLSPPPEASRLSP 628
Query: 816 SSSDSATRDPSTSVPASGAHQ-------------PPQTTEGEKSPEPLGLPQSQSAQA-- 860
DS P P S + P E SP P P S +A
Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
Query: 861 LTPPPIPNGSAP---EGPASP 878
L+PPP + ++P + PASP
Sbjct: 689 LSPPPEDSPTSPPPEDSPASP 709
Score = 47.8 bits (112), Expect = 5e-05
Identities = 57/189 (30%), Positives = 71/189 (37%), Gaps = 49/189 (25%)
Query: 696 TPLSYPSPGPQPPGPSWTAT-FDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPT 754
+PLS P P P P A+ P P + P SP E LH P + PLS P P
Sbjct: 447 SPLS-PPPEESPTSPPPEASRLSPPPEELPASPL---PEALHLSRPLEESPLSPP---PE 499
Query: 755 QSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSA 814
+S SPP P S+P E S ++ P S
Sbjct: 500 ESPLSPP-------------PESSPFSPLEESPLSPPE-------------------ESP 527
Query: 815 PSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQA--LTPPPIPNGSAP 872
PS A P + P + PP E SP P LP S +A L+PPP + +P
Sbjct: 528 PSP---ALETPLSPPPEASPLSPP-FEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP 583
Query: 873 ---EGPASP 878
E P SP
Sbjct: 584 PPEESPMSP 592
Score = 41.6 bits (96), Expect = 0.003
Identities = 49/190 (25%), Positives = 68/190 (35%), Gaps = 29/190 (15%)
Query: 702 SPGPQPPGPSWTATFDP--VPTD----APTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQ 755
+P PQPP P P +P+D P SP+ + Q PL+ P+ L +
Sbjct: 2384 TPRPQPPPPESCCALPPRSLPSDPFSRVPASPQ---------SQSSSQSPLT-PRPLSAE 2433
Query: 756 SLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSI--GDLQATFHGIRS 813
+ P Q PPS PQ + + +P P V+ G L T G
Sbjct: 2434 AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGG 2493
Query: 814 APSSSDSATRDPSTSVPASGAHQPPQTTE--------GEKSPEPLGLPQSQSAQALTPP- 864
P++ + + SG QPP G SP PQ+ +L PP
Sbjct: 2494 FPAALPAGPAGELHAKVPSG--QPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPV 2551
Query: 865 PIPNGSAPEG 874
P P P G
Sbjct: 2552 PQPGLPPPHG 2561
Score = 40.4 bits (93), Expect = 0.007
Identities = 50/177 (28%), Positives = 69/177 (38%), Gaps = 15/177 (8%)
Query: 696 TPLSYPSPGPQPPGPSWTAT-FDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPT 754
+PLS P P P P A+ P P D+P SP EE PP LS LP
Sbjct: 606 SPLS-PPPEESPLSPPPEASRLSPPPEDSPMSPP---PEESPMSPPPEVSRLSP---LPV 658
Query: 755 QSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTE---PSAPCQALVSIGDLQATFHGI 811
S SPP ++ + +P S P EA+ S E S P + + + + +
Sbjct: 659 VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718
Query: 812 RSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSP---EPLGLPQSQSAQALTPPP 865
S +P + G H P+ E SP EP PQ++ L+P P
Sbjct: 719 PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPH-LSPQP 774
Score = 37.7 bits (86), Expect = 0.047
Identities = 44/168 (26%), Positives = 67/168 (39%), Gaps = 27/168 (16%)
Query: 722 DAPTSPRVSGEEELHT-----GPPAPQGPLSVPQ--GLPTQSLASPPARDALQLRSQDPT 774
D+P+S G EL T P P+ PQ GL + PPA+ + P+
Sbjct: 2308 DSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQ------ALAPS 2361
Query: 775 PPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGA 834
PPS P GS T+P A R P +S P S+P+
Sbjct: 2362 PPSHPDIFRPGS-YTDPYAQPPLTP------------RPQPPPPESCCALPPRSLPSDPF 2408
Query: 835 HQPPQTTEGEKSPEPLGLPQSQSAQALTPPPI-PNGSAPEGPASPGSQ 881
+ P + + + S + P+ SA+A P P+ P +P+ + P S+
Sbjct: 2409 SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456
Score = 37.0 bits (84), Expect = 0.081
Identities = 49/164 (29%), Positives = 63/164 (38%), Gaps = 15/164 (9%)
Query: 723 APTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEA 782
AP +PR S E P +P L + P Q+LA P R T P A
Sbjct: 2329 APLTPRASQVE-----PQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL 2383
Query: 783 TEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASG-AHQPPQTT 841
T + P + C AL F + ++P S S+++ P T P S A P T
Sbjct: 2384 TPRPQPPPPESCC-ALPPRSLPSDPFSRVPASPQSQ-SSSQSPLTPRPLSAEAFCPSPVT 2441
Query: 842 EGEKSPEPLGLPQS--QSAQALTP---PPIPNGSAPEGPASPGS 880
+SP+P P S QS P PP P PE GS
Sbjct: 2442 PRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP--QPPEVAFKAGS 2483
Score = 37.0 bits (84), Expect = 0.081
Identities = 42/162 (25%), Positives = 62/162 (38%), Gaps = 14/162 (8%)
Query: 703 PGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPA 762
P P P P +P+ + P + H G P PQGP P P ++ A
Sbjct: 4307 PTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEP---PPGRVSPAAA 4363
Query: 763 RDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSAT 822
+ A L S+ P P E K P Q+ + G L +G +S S
Sbjct: 4364 QLADTLFSKGLGPWDPPDNLAETQK------PEQSSLVPGHLDQV-NGQVVPEASQLSIK 4416
Query: 823 RDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPP 864
++P A GA Q+ + E + EP+G P + + L P
Sbjct: 4417 QEPREEPCALGA----QSVKREANGEPIGAPGTSNHLLLAGP 4454
Score = 35.0 bits (79), Expect = 0.31
Identities = 49/213 (23%), Positives = 74/213 (34%), Gaps = 21/213 (9%)
Query: 686 GIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPT------SPRVSGEEELHTGP 739
G+ +A G P + PGP PG + VP P+ +P E T P
Sbjct: 2134 GLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAP 2193
Query: 740 PAPQGPLSVPQGLPTQ--SLASPPARDALQLRSQDPTPPSAPQ-EATEGSKVTEPSAPCQ 796
P P P G P Q L + A Q TPP P+ + + +P P
Sbjct: 2194 PT-YPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSL 2252
Query: 797 ALVSIGDLQATFHGIRSAPSSSDSATRDPSTSV--------PASGAHQPPQT--TEGEKS 846
+++ + G S P S + ++ +S ++ PP + S
Sbjct: 2253 DNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSS 2312
Query: 847 PEPLGLPQSQSAQALTPPPIPNGSAPEGPASPG 879
LG + ++ P P S E P SPG
Sbjct: 2313 GTHLGGLELKTPDVFKAPLTPRASQVE-PQSPG 2344
Score = 33.9 bits (76), Expect = 0.68
Identities = 39/166 (23%), Positives = 54/166 (32%), Gaps = 31/166 (18%)
Query: 691 ARGGATPLSYPSPGP-----------QPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGP 739
AR G P + GP GP W FD V ++ L
Sbjct: 4824 ARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQES 4883
Query: 740 PAPQGPLSVP-----QGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEP--S 792
PAP+ P L + L++PP ++P+PP +P + S TEP
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPP--------EEPSPPPSPLAPSPASPPTEPLVE 4935
Query: 793 APCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPP 838
P + L + SS +SA P P G P
Sbjct: 4936 LPTEPLA-----EPPVPSPLPLASSPESARPKPRARPPEEGEDSRP 4976
Score = 33.5 bits (75), Expect = 0.89
Identities = 42/166 (25%), Positives = 58/166 (34%), Gaps = 12/166 (7%)
Query: 701 PSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASP 760
P P+ GP P P + SPR EE H P A + LS P L +
Sbjct: 732 PQLCPRSEGPH----LSPRPEEPHLSPR---PEEPHLSPQAEEPHLSPQPEEPC--LCAV 782
Query: 761 PARDALQLRSQDPTPPSAPQEATEGSKVTEPS-APCQALVSIGDLQATFHGIRSAPSSSD 819
P L +++ P P+E + EP +P + H S S
Sbjct: 783 PEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH--LSPQSEEP 840
Query: 820 SATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPP 865
+ P S + +PP + EK PE G + L PPP
Sbjct: 841 CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPP 886
Score = 33.1 bits (74), Expect = 1.2
Identities = 52/187 (27%), Positives = 68/187 (36%), Gaps = 24/187 (12%)
Query: 691 ARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQ 750
+R PL P P PQPP ++ A + A TS G PA + VP
Sbjct: 2459 SRDPFAPLHKP-PRPQPPEVAFKAG-----SLAHTSLGAGGFPAALPAGPAGELHAKVPS 2512
Query: 751 GLPTQSLASPPARDALQLRSQDP-TPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFH 809
G P + SP + S T P A E + V +P P H
Sbjct: 2513 GQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPP------------H 2560
Query: 810 GIRSAPSSSDSATRDPSTSVP-ASGAHQPPQTTEGEKSP---EPLGLPQSQSAQALTPPP 865
GI S + + ST+ A+G P + G S E GL + L PPP
Sbjct: 2561 GINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL-PPP 2619
Query: 866 IPNGSAP 872
P+GS P
Sbjct: 2620 APDGSLP 2626
Score = 32.0 bits (71), Expect = 2.6
Identities = 50/199 (25%), Positives = 61/199 (30%), Gaps = 45/199 (22%)
Query: 705 PQPP--GPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLS--------------- 747
P+ P P P P T P L P +P GP S
Sbjct: 969 PESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLL 1028
Query: 748 ----VPQGLPTQSLASPPARDALQLRSQDPTPP---------SAPQEATEGSKVTEPSAP 794
VPQ P S SPP AL L P P A E KV+EP P
Sbjct: 1029 QHSLVPQNSP-PSQCSPP---ALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECP 1084
Query: 795 CQALVSIGDLQATFHGIRSAPSSSDSATRD----------PSTSVPASGAHQPPQTTEGE 844
+ L + G S P+ S + D P + A G+ P T G
Sbjct: 1085 ALEPSATSPLPSPM-GDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGS 1143
Query: 845 KSPEPLGLPQSQSAQALTP 863
+ E G P + L P
Sbjct: 1144 LASELKGSPVLLDPEELAP 1162
Score = 31.6 bits (70), Expect = 3.4
Identities = 48/200 (24%), Positives = 68/200 (34%), Gaps = 29/200 (14%)
Query: 702 SPGPQPPGPSWTATFDPVPTDAPTSPRVSGE------EELHTGPPAPQGPLSVPQGLPTQ 755
SP P+ P P P ++ SP+ EE H P + PLS P +
Sbjct: 816 SPVPEEP------CLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPE 869
Query: 756 SLASPPARDALQLRSQDPTPPSAP--QEATEGSKVTEPSAPCQALVSIGDLQATFHGIRS 813
PA + L L P +P E P +P + + +
Sbjct: 870 EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929
Query: 814 APSSSDSATRDPSTSVPASGAHQP------PQTTEGEKSPE-PLGLPQSQSAQALTPPPI 866
P P + A A P P +G+ PE PL P ++ ++PPP
Sbjct: 930 MPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILET--PISPPPE 987
Query: 867 PNGSAPEG------PASPGS 880
N + PE P SPGS
Sbjct: 988 ANCTDPEPVPPMILPPSPGS 1007
Score = 30.0 bits (66), Expect = 9.9
Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 3/67 (4%)
Query: 814 APSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPE 873
+P +S T P AS PP+ PE L L + L+PPP + +P
Sbjct: 450 SPPPEESPTSPPPE---ASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506
Query: 874 GPASPGS 880
+SP S
Sbjct: 507 PESSPFS 513
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 52.8 bits (125), Expect = 1e-06
Identities = 47/188 (25%), Positives = 62/188 (32%), Gaps = 12/188 (6%)
Query: 697 PLSYPSPGPQPPGPSWTATFDPVPTDAPTSPR---VSGEEELHTGPP--APQGPLSVPQG 751
P + PSP P P T T P PT P+ P ++ T PP P P +
Sbjct: 1473 PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTT 1532
Query: 752 LPTQSLASPPARDALQLRSQ------DPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQ 805
P + SPP + + TP P T T PS P S +
Sbjct: 1533 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTIT 1592
Query: 806 ATFHGIRSAPS-SSDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPP 864
T + PS + + T P T+ P+ P + P P TPP
Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1652
Query: 865 PIPNGSAP 872
P S P
Sbjct: 1653 PTTTPSPP 1660
Score = 52.4 bits (124), Expect = 2e-06
Identities = 44/181 (24%), Positives = 66/181 (36%), Gaps = 12/181 (6%)
Query: 698 LSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSL 757
++ PSP P P T+T PT P+ P + T P+P P++ P +
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSP--PITTTTTPPPTTT 1453
Query: 758 ASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSS 817
SPP + PT +P T T PS P + S P++
Sbjct: 1454 PSPPISTT---TTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP-----SPPTT 1505
Query: 818 SDSATRDPSTSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPAS 877
+ +T++P + PP TT +P P P + +TPP P S
Sbjct: 1506 TPITPPASTTTLPPTTTPSPPTTT--TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1563
Query: 878 P 878
P
Sbjct: 1564 P 1564
Score = 52.4 bits (124), Expect = 2e-06
Identities = 44/175 (25%), Positives = 62/175 (35%), Gaps = 9/175 (5%)
Query: 703 PGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPA 762
P P P T T P PT P+ P + + P P + P PT + PP
Sbjct: 1597 PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP--PTTTPSPPPTTTTTPPPT 1654
Query: 763 RDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSAT 822
+ P+PP T T PS+P S T + PSS + T
Sbjct: 1655 TTPSPPTTTTPSPPITT--TTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712
Query: 823 RDPSTSV-----PASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAP 872
PS++ P + P TT + LP + ++ LT P+P P
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP 1767
Score = 42.0 bits (97), Expect = 0.003
Identities = 48/181 (26%), Positives = 61/181 (33%), Gaps = 28/181 (15%)
Query: 696 TPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEE----ELHTGPPAPQGPLSVPQG 751
TP +P P + T T P PT T P EL T P P+ S PQ
Sbjct: 4166 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPES--STPQ- 4222
Query: 752 LPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGI 811
T S P ++ L S P A E + PS P + G H +
Sbjct: 4223 --TSRSTSSPLTESTTLLSTLPP-------AIEMTSTAPPSTPTAPTTTSGG-----HTL 4268
Query: 812 RSAPSSSDSATRDP-------STSVPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPP 864
PS++ S P S+S P Q T+ +P PL P L P
Sbjct: 4269 SPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPY 4328
Query: 865 P 865
P
Sbjct: 4329 P 4329
Score = 40.4 bits (93), Expect = 0.007
Identities = 48/194 (24%), Positives = 74/194 (38%), Gaps = 22/194 (11%)
Query: 693 GGATPLSYP-------SPGPQPPGPSWTATFDPVPTDAPTSPRVSGE-EELHTGPPAPQG 744
G TP + P +P P P G T T P+ T +P + + T P
Sbjct: 4123 GTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4181
Query: 745 PLSVPQGLPTQSLASPPARDA----LQLRSQDPTPPSA-PQEA-TEGSKVTEPSAPCQAL 798
P PT + PP + +L + +P P S+ PQ + + S +TE + L
Sbjct: 4182 TTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTL 4241
Query: 799 VSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPP-----QTTEGEKSPEPLGLP 853
++ +T S P++ + + + S P S PP TT G S
Sbjct: 4242 PPAIEMTST--APPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTV 4299
Query: 854 QSQSAQALTPPPIP 867
Q+ + A TP P P
Sbjct: 4300 QTTTTSAWTPTPTP 4313
Score = 39.7 bits (91), Expect = 0.012
Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 8/104 (7%)
Query: 702 SPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQ-------GPLSVPQGLPT 754
SP P P T P PT P+SP + T P+P P + P T
Sbjct: 1683 SPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTT 1742
Query: 755 QSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQAL 798
PP + L + P PPS T P+ PC L
Sbjct: 1743 TMTTLPPTTTSSPLTTT-PLPPSITPPTFSPFSTTTPTTPCVPL 1785
Score = 33.1 bits (74), Expect = 1.2
Identities = 41/190 (21%), Positives = 63/190 (33%), Gaps = 16/190 (8%)
Query: 696 TPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQ 755
TP +P P + T T P PT T P + T P P P G T
Sbjct: 4051 TPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTP-----TPTGTQT- 4103
Query: 756 SLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSA- 814
P + PTP + + +T + G T I +
Sbjct: 4104 ----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4159
Query: 815 ---PSSSDSATRDPSTS-VPASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGS 870
P+ + + T+ P+T+ + + P T G ++ P + A+ T P P S
Sbjct: 4160 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESS 4219
Query: 871 APEGPASPGS 880
P+ S S
Sbjct: 4220 TPQTSRSTSS 4229
Score = 31.2 bits (69), Expect = 4.4
Identities = 26/91 (28%), Positives = 33/91 (36%), Gaps = 4/91 (4%)
Query: 697 PLSYPSPGPQP-PGPSWTATFDPVPTDAPTSPRV---SGEEELHTGPPAPQGPLSVPQGL 752
P + PSP P P T T P PT P+SP S T P P S
Sbjct: 1653 PTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712
Query: 753 PTQSLASPPARDALQLRSQDPTPPSAPQEAT 783
T S + P+ + + PT +P T
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT 1743
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 52.4 bits (124), Expect = 2e-06
Identities = 60/261 (22%), Positives = 105/261 (40%), Gaps = 55/261 (21%)
Query: 614 KDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPG---VRSGGSTDS 670
K + D ++ E+EEE QG A R+G PPG ++ S+ S
Sbjct: 79 KKKASSSDSEDSSEEEEEVQGPPAKKAAVPA---------KRVGLPPGKAAAKASESSSS 129
Query: 671 EDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVS 730
E+ ++D+EE++ ++ + + G P + + P S + D S
Sbjct: 130 EESSDDDDEEDQKKQPV----QKGVKPQAKAAKAPPKKAKSSDSDSDS-----------S 174
Query: 731 GEEELHTGPPAPQGPLSVPQGLPTQSLASP-PARDALQL---------RSQDPTPPSAPQ 780
E+E PP Q P P + Q+ A P PAR A ++ S + S
Sbjct: 175 SEDE----PPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDS 230
Query: 781 EATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRD-------------PST 827
E + + + + P + +V+ ++A R + SS DS++ + P +
Sbjct: 231 EEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYS 290
Query: 828 SVPASGAHQPPQTTEGEKSPE 848
SVP A PP+ + G + P+
Sbjct: 291 SVPPPSA-PPPKKSLGTQPPK 310
Score = 40.8 bits (94), Expect = 0.006
Identities = 58/250 (23%), Positives = 88/250 (35%), Gaps = 33/250 (13%)
Query: 660 PGVRSGGSTDSE-DEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDP 718
P +S S DS DEEEE ++ +++ G + + P S G QPP + P
Sbjct: 260 PTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKA-VEKQQP 318
Query: 719 VPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQL-RSQDPTPPS 777
V + +S E PP P A+ + D+ S+D PS
Sbjct: 319 VESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPS 378
Query: 778 APQEATEGSK----------VTEPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPST 827
P T+ S +P+A + V G T S+ S++ + T
Sbjct: 379 KPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKT 438
Query: 828 -----------------SVPASGAHQPPQTTEGEK---SPEPLGLPQSQSAQALTPPPIP 867
S+PA A Q + + + S E S+SA P +
Sbjct: 439 KKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVA 498
Query: 868 NGSAPEGPAS 877
G+AP PAS
Sbjct: 499 GGAAPSKPAS 508
Score = 33.5 bits (75), Expect = 0.89
Identities = 54/268 (20%), Positives = 95/268 (35%), Gaps = 23/268 (8%)
Query: 621 DDDEEEEDEEEAQGSGESDGEDG----AWQGSQLARGARLGQPPG------VRSGGSTDS 670
D D E+DE ++ +G + + + A QP G R S+ S
Sbjct: 367 DSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSS 426
Query: 671 EDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVS 730
E+E EEE+ ++ + + P Q P S ++ D +D+ +S
Sbjct: 427 EEESS-SSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSD---SDSSSSEE-- 480
Query: 731 GEEELHTGPPAPQGPLSVPQG-LPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVT 789
EEE + + P V G P++ ++ + S +E +G
Sbjct: 481 -EEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSP 539
Query: 790 EPSAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSPEP 849
P AP + G T ++A +S + +V S + + + E + E
Sbjct: 540 RPQAP----KANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKE- 594
Query: 850 LGLPQSQSAQALTPPPIPNGSAPEGPAS 877
PQ++ + TP P E AS
Sbjct: 595 AETPQAKKIKLQTPNTFPKRKKGEKRAS 622
Score = 33.1 bits (74), Expect = 1.2
Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 17/101 (16%)
Query: 614 KDRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGSTDSEDE 673
+D D EE+EE+ S + ++A GA +P + G + S
Sbjct: 467 RDSSSDSDSSSSEEEEEKTSKSAVKK------KPQKVAGGAAPSKPASAKKGKAESSNSS 520
Query: 674 EEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTA 714
+D EEE+E+ G SP PQ P + T+
Sbjct: 521 SSDDSSEEEEEKLKGKG-----------SPRPQAPKANGTS 550
Score = 32.3 bits (72), Expect = 2.0
Identities = 56/243 (23%), Positives = 85/243 (34%), Gaps = 39/243 (16%)
Query: 659 PPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDP 718
P ++ S D E+ EEEEE + G A+ A P PPG +
Sbjct: 73 PVAKKAKKKASSSDSEDSSEEEEEVQ---GPPAKKAAVPAKRVG---LPPGKA------- 119
Query: 719 VPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLA--SPPAR----DALQLRSQD 772
A S S EE Q V +G+ Q+ A +PP + D+ S +
Sbjct: 120 ---AAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSE 176
Query: 773 PTPPSAPQ----EATEGSKVTEPSAPCQALVSIGDLQATFHGIRSAPSSS------DSAT 822
PP + T ++ P P +A I + +A S+ SSS + A
Sbjct: 177 DEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAA 236
Query: 823 RDPSTSVPASG--AHQPPQ-----TTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGP 875
P +VP A P + T + S + + + + + P P S P
Sbjct: 237 ATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPS 296
Query: 876 ASP 878
A P
Sbjct: 297 APP 299
Score = 30.4 bits (67), Expect = 7.5
Identities = 40/160 (25%), Positives = 59/160 (36%), Gaps = 36/160 (22%)
Query: 730 SGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVT 789
S EEE GPPA + +P + + PP + A + + S+ + E K
Sbjct: 91 SEEEEEVQGPPAKKA------AVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQK-- 142
Query: 790 EPSAPCQALV--SIGDLQATFHGIRSAPSSSDSATRDPSTSVPASGAHQPPQTTEGEKSP 847
P Q V +A +S+ S SDS++ D +PP K+
Sbjct: 143 --KQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSED-----------EPP------KNQ 183
Query: 848 EPLGLPQSQSAQALTP-------PPIPNGSAPEGPASPGS 880
+P P + AQ P P I NG A +S S
Sbjct: 184 KPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSS 223
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/80 (38%), Positives = 40/80 (50%), Gaps = 18/80 (22%)
Query: 624 EEEEDEEEAQGSGESDGED---------------GAWQGSQLA---RGARLGQPPGVRSG 665
EE EDE EA+G G+++GED G + +L+ G GV G
Sbjct: 792 EECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDG 851
Query: 666 GSTDSEDEEEEDEEEEEDEE 685
G +D D EEE+EEEEE EE
Sbjct: 852 GGSDGGDSEEEEEEEEEQEE 871
Score = 35.0 bits (79), Expect = 0.31
Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 626 EEDEEEAQGSGESDGEDG--AWQGSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEEEED 683
+ED EA+ +GE GE+G A +G + QP G G T+++ + EE E+E E
Sbjct: 744 QEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEG---EGETETQGKGEECEDENEA 800
Query: 684 E 684
E
Sbjct: 801 E 801
Score = 34.3 bits (77), Expect = 0.52
Identities = 26/82 (31%), Positives = 33/82 (40%), Gaps = 37/82 (45%)
Query: 622 DDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGSTDSEDEEEEDEEEE 681
D EEEE+EEE Q E + E++EEE+EEEE
Sbjct: 858 DSEEEEEEEEEQEEEE-------------------------------EEEEQEEEEEEEE 886
Query: 682 EDEEGIGCAARGGATPLSYPSP 703
E+EE +G PLS P
Sbjct: 887 EEEE------KGNEEPLSLDWP 902
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 52.4 bits (124), Expect = 2e-06
Identities = 63/208 (30%), Positives = 75/208 (36%), Gaps = 37/208 (17%)
Query: 690 AARGGATPLSYPSPGPQPPGPSWTATFDPVPTDAPT-SPRVSGEEELHTG---------- 738
AAR + P+P P P P P+P+ +P +P VS L G
Sbjct: 161 AARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVP 220
Query: 739 ---PPAPQGPLSVPQGLPTQSLASP----PARDALQLRSQDPTPPSAPQEATEGSKVTEP 791
PP P P P LP S+ S P L L P P P G K EP
Sbjct: 221 CAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKA-EP 279
Query: 792 SAPCQALVSIGDLQATFHGIRSAPSSSDSATRDPSTSVPA-------SGAHQPPQTTEGE 844
++P Q D Q P A+ P S+PA S + PP
Sbjct: 280 ASPAQ------DAQEP---PAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPP-- 328
Query: 845 KSPEPLGLPQSQSAQALTPPPIPNGSAP 872
KSP PQ AQAL PP P GS P
Sbjct: 329 KSPSFQAPPQKAGAQALPAPPAPPGSQP 356
Score = 42.7 bits (99), Expect = 0.001
Identities = 50/201 (24%), Positives = 66/201 (32%), Gaps = 26/201 (12%)
Query: 695 ATPLSYPSPGPQPPGPSWTATFDP--VPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGL 752
A P+ P P PP P P V +D P+++ LH P P PL P G
Sbjct: 216 APPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLA---PLHLPPIPPPLPLLPPCGY 272
Query: 753 PTQSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIR 812
P L + PA A + PP P A+ + + P+ P + S +
Sbjct: 273 P--GLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKS 330
Query: 813 ---SAPSSSDSATRDPSTSVP----------------ASGAHQPPQTTEGEKSPEPLGLP 853
AP A P+ P A G P +SP
Sbjct: 331 PSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSS 390
Query: 854 QSQSAQALTPPPIPNGSAPEG 874
+SQ A A TP P G G
Sbjct: 391 KSQQATAWTPTQQPGGQLRNG 411
Score = 40.0 bits (92), Expect = 0.010
Identities = 51/196 (26%), Positives = 64/196 (32%), Gaps = 31/196 (15%)
Query: 697 PLSYPSPGPQPPGPSWTATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPL--SVPQGLPT 754
P+ P P P PP P P P AP P + L P + L + QG
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAP--PVSTDTSSLRRADPKGRSALLADIQQGTRL 59
Query: 755 QSLASPPARDALQLRSQDPTPPSAPQEATEGSKVTEPSAPCQALVSIGDLQATFHGIRSA 814
+ + R A Q+ S T A T P ++GDL A +
Sbjct: 60 RKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPP--------TLGDLFAGGFPVLRP 111
Query: 815 PSSSDSA---------TRDPSTSVP---ASGAHQPPQTTEGEKSPEPLGLPQSQSAQALT 862
D A +R PS +P SG PP + LG A T
Sbjct: 112 AGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPR-------LGNTSEAHGAART 164
Query: 863 PPPIPNGSAPEGPASP 878
PP PN AP P P
Sbjct: 165 APPRPNVPAPPPPTPP 180
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,880,244
Number of Sequences: 37866
Number of extensions: 2467057
Number of successful extensions: 35889
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 364
Number of HSP's successfully gapped in prelim test: 1587
Number of HSP's that attempted gapping in prelim test: 17272
Number of HSP's gapped (non-prelim): 11510
length of query: 881
length of database: 18,247,518
effective HSP length: 111
effective length of query: 770
effective length of database: 14,044,392
effective search space: 10814181840
effective search space used: 10814181840
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.