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Search of human proteins with 150456463
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150456463 gasdermin 1 [Homo sapiens]
(445 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150456463 gasdermin 1 [Homo sapiens] 870 0.0
gi|83320070 gasdermin D [Homo sapiens] 196 4e-50
gi|13899221 melanoma-derived leucine zipper, extra-nuclear facto... 176 4e-44
gi|109689703 gasdermin-like isoform 1 [Homo sapiens] 135 1e-31
gi|109689711 gasdermin-like isoform 2 [Homo sapiens] 131 1e-30
gi|111607457 deafness, autosomal recessive 59 [Homo sapiens] 63 5e-10
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 41 0.003
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 37 0.028
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 37 0.036
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 34 0.31
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 34 0.31
gi|115430239 spectrin, beta, non-erythrocytic 4 isoform sigma5 [... 34 0.31
gi|169168964 PREDICTED: hypothetical protein LOC100131031 [Homo ... 33 0.40
gi|169168628 PREDICTED: hypothetical protein LOC100131031 [Homo ... 33 0.40
gi|169169551 PREDICTED: hypothetical protein LOC100131031 [Homo ... 33 0.40
gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13... 32 0.89
gi|4506975 solute carrier family 12 (sodium/potassium/chloride t... 32 0.89
gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 32 0.89
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 32 1.2
gi|50086624 integrator complex subunit 4 [Homo sapiens] 32 1.5
gi|19923193 heat shock 70kD protein binding protein [Homo sapiens] 32 1.5
gi|100814339 coiled-coil domain containing 146 [Homo sapiens] 32 1.5
gi|118498362 kinectin 1 isoform b [Homo sapiens] 31 2.0
gi|118498356 kinectin 1 isoform a [Homo sapiens] 31 2.0
gi|118498368 kinectin 1 isoform c [Homo sapiens] 31 2.0
gi|33620775 kinectin 1 isoform a [Homo sapiens] 31 2.0
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 31 2.0
gi|7661788 mediator complex subunit 4 [Homo sapiens] 31 2.0
gi|19923403 exosome component 2 [Homo sapiens] 31 2.0
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 31 2.6
>gi|150456463 gasdermin 1 [Homo sapiens]
Length = 445
Score = 870 bits (2249), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 1 MTMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTL 60
MTMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTL
Sbjct: 1 MTMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTL 60
Query: 61 LDVLEPGSSPSDPTDTGNFGFKNMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLEVQTLSV 120
LDVLEPGSSPSDPTDTGNFGFKNMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLEVQTLSV
Sbjct: 61 LDVLEPGSSPSDPTDTGNFGFKNMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLEVQTLSV 120
Query: 121 APKALETVQERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEACFSLPFF 180
APKALETVQERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEACFSLPFF
Sbjct: 121 APKALETVQERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEACFSLPFF 180
Query: 181 APLGLQGSINHKEAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQTFPPGEKSGEE 240
APLGLQGSINHKEAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQTFPPGEKSGEE
Sbjct: 181 APLGLQGSINHKEAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQTFPPGEKSGEE 240
Query: 241 KVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLE 300
KVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLE
Sbjct: 241 KVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLE 300
Query: 301 LALEGALDKGHEVTLEALPKDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILP 360
LALEGALDKGHEVTLEALPKDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILP
Sbjct: 301 LALEGALDKGHEVTLEALPKDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILP 360
Query: 361 VQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTEALVGLSGLEVQRSGPQYMW 420
VQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTEALVGLSGLEVQRSGPQYMW
Sbjct: 361 VQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTEALVGLSGLEVQRSGPQYMW 420
Query: 421 DPDTLPRLCALYAGLSLLQQLTKAS 445
DPDTLPRLCALYAGLSLLQQLTKAS
Sbjct: 421 DPDTLPRLCALYAGLSLLQQLTKAS 445
>gi|83320070 gasdermin D [Homo sapiens]
Length = 484
Score = 196 bits (498), Expect = 4e-50
Identities = 156/480 (32%), Positives = 239/480 (49%), Gaps = 43/480 (8%)
Query: 4 FENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTLLDV 63
FE V R + ++L+ G+ P+ SL F P+CLV+RK S+ FW RY + ++ D+
Sbjct: 5 FERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLSIKDI 64
Query: 64 LEPGSSPSDPTDTGNFGFKNMLDTRVEGDVDV--PKTVKVKGTAGLSQNS--TLEVQTLS 119
LEP ++ D +F F + +D +++G V++ P K+ G A +S +S ++ V +LS
Sbjct: 65 LEPDAAEPDVQRGRSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDSSSTSMNVYSLS 124
Query: 120 VAPKALET-VQERKL-AADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEAC--F 175
V P +T + ER L +H L++++ +G+N+YVV EV++T +EV + R K E F
Sbjct: 125 VDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVTRTHKREGSGRF 184
Query: 176 SLPFFAPL--GLQGSINHKEAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQTFPP 233
SLP L QG ++ K+ VTIP G LAFRV QL++ + D+ + +TF P
Sbjct: 185 SLPGATCLQGEGQGHLSQKKTVTIPSGSTLAFRVAQLVI--DSDLDVLLFPDKKQRTFQP 242
Query: 234 ---GEKSGEEKVILIQASD------------------VGDVHEGFRTLKEEVQRETQQVE 272
G K + Q G E F+ L+ EV+ ++++E
Sbjct: 243 PATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQGLRAEVETISKELE 302
Query: 273 KLSRVGQSSLLSSLSKLLGKKKELQDLELALEGA--------LDKGHEVTLEALP-KDVL 323
L R LL L +L + L+ LE ALE LD LE L +
Sbjct: 303 LLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPAGAVLECLVLSSGM 362
Query: 324 LSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFP 383
L E ++Y +GALT LSE Q KLL +++E + L L+LV S +EQ+ +
Sbjct: 363 LVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLLEQSAPWQERSTMS 422
Query: 384 LQPELLSSLGDEELTLTEALVGLSGLEVQRSGPQYMWDPDTLPRLCALYAGLSLLQQLTK 443
L P LL + E L+ GLE+ P W+P R+CALYA L+LL L++
Sbjct: 423 LPPGLLGNSWGEGAP-AWVLLDECGLELGEDTPHVCWEPQAQGRMCALYASLALLSGLSQ 481
>gi|13899221 melanoma-derived leucine zipper, extra-nuclear factor
[Homo sapiens]
Length = 508
Score = 176 bits (446), Expect = 4e-44
Identities = 155/510 (30%), Positives = 244/510 (47%), Gaps = 71/510 (13%)
Query: 2 TMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKS-TLFWG-ARYVRTDYT 59
+M E +++ L +++ + DLTP+ L+ + F ++ +K+ S + FW + YV +++
Sbjct: 3 SMLERISKNLVKEIGSK-DLTPVKYLLSATKLRQFVILRKKKDSRSSFWEQSDYVPVEFS 61
Query: 60 LLDVLEPGSSPSDPTDTGNFGFKNMLDTRVEGD--VDVPKTVKVKGTAGLSQNSTLEVQT 117
L D+LEP SS + TG F F +++ + + D V+V V V G A + +LE Q
Sbjct: 62 LNDILEPSSSVLETVVTGPFHFSDIMIQKHKADMGVNVGIEVSVSGEASVDHGCSLEFQI 121
Query: 118 LSVAPKALETVQERKLAADHP-FLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEACFS 176
+++ LE Q+RKL P FLKE + +G+NLYVV E VE + L +
Sbjct: 122 VTIPSPNLEDFQKRKLLDPEPSFLKECRRRGDNLYVVTEAVELINNTVLYDSSSVNILGK 181
Query: 177 LPFFAPLGL-QGSIN----HKEAVTIPKGCVLAFRVRQLMVKGK--------------DE 217
+ + G QG K+A+T+ KG V+A++ +QL++K K DE
Sbjct: 182 IALWITYGKGQGQGESLRVKKKALTLQKGMVMAYKRKQLVIKEKAILISDDDEQRTFQDE 241
Query: 218 WDI----------------------PHICNDN------------MQTFPPGEKSGEEKVI 243
++I P + N + Q F G E+V
Sbjct: 242 YEISEMVGYCAARSEGLLPSFHTISPTLFNASSNDMKLKPELFLTQQFLSGHLPKYEQVH 301
Query: 244 LIQASDVGD-VHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQD---- 298
++ + + + F+ L+EEV ++ + + +LS+ Q + S+ +L + LQD
Sbjct: 302 ILPVGRIEEPFWQNFKHLQEEVFQKIKTLAQLSKDVQDVMFYSILAMLRDRGALQDLMNM 361
Query: 299 LELALEGALDKGHEVTLEALPKDVLLSKEA----VGAILYFVGALTELSEAQQKLLVKSM 354
LEL G LD L+ L +D S A ILY + A+ LS+ Q LL SM
Sbjct: 362 LELDSSGHLDGPGGAILKKLQQD---SNHAWFNPKDPILYLLEAIMVLSDFQHDLLACSM 418
Query: 355 EKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTEALVGLSGLEVQRS 414
EK+IL Q +LV S +E NF F L+PELL+ L E L +T L+ GL ++
Sbjct: 419 EKRILLQQQELVRSILEPNFRYPWSIPFTLKPELLAPLQSEGLAITYGLLEECGLRMELD 478
Query: 415 GPQYMWDPDTLPRLCALYAGLSLLQQLTKA 444
P+ WD + L ALY LSLLQQL +A
Sbjct: 479 NPRSTWDVEAKMPLSALYGTLSLLQQLAEA 508
>gi|109689703 gasdermin-like isoform 1 [Homo sapiens]
Length = 403
Score = 135 bits (339), Expect = 1e-31
Identities = 131/462 (28%), Positives = 217/462 (46%), Gaps = 88/462 (19%)
Query: 2 TMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTLL 61
++FE +TR + ++++ GD+ + SL+D RF F LV KR F+G R+ T TL+
Sbjct: 3 SVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRT---FFGCRHYTTGLTLM 59
Query: 62 DVLEP-GSSPSDPTDTGNFGFK------NMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLE 114
D+L+ G D D+G G K + +D+ E V +PK + + G+ + ++
Sbjct: 60 DILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIK 119
Query: 115 VQTLSVAPKALETVQERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEAC 174
+ ++ + L T++ RKL + PF + ENLY+V E +ETV+E TL+ + +
Sbjct: 120 ISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYK-- 177
Query: 175 FSLPFFAPLGLQGSINHK----EAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQT 230
F++ + QG +++K VTIP VL++RV+QL+
Sbjct: 178 ----FWSQIS-QGHLSYKHKGQREVTIPPNRVLSYRVKQLV------------------- 213
Query: 231 FPPGEKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLL 290
FP E ++ +G E R +KE+++ ++ L+ + +L+SL+K L
Sbjct: 214 FPNKETMKKDGASSCLGKSLGS--EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCL 271
Query: 291 GKKKELQDLELALEGALDKGHEVTLEALPKDVL---------LSKEAVGAILYFVGALTE 341
GK+ QDLE + L G E+ +E K +L L + AIL F+ AL E
Sbjct: 272 GKEDIRQDLEQRVSEVLISG-ELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLE 330
Query: 342 LSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTE 401
LSE QQ + +++EK LP+ V+S MEQN+
Sbjct: 331 LSEEQQ-FVAEALEKGTLPLLKDQVKSVMEQNW--------------------------- 362
Query: 402 ALVGLSGLEVQRSGPQYMWDPDTLPRLCALYAGLSLLQQLTK 443
E+ S P +DP+ LCALY +S+L +L +
Sbjct: 363 -------DELASSPPDMDYDPEA-RILCALYVVVSILLELAE 396
>gi|109689711 gasdermin-like isoform 2 [Homo sapiens]
Length = 394
Score = 131 bits (329), Expect = 1e-30
Identities = 129/462 (27%), Positives = 214/462 (46%), Gaps = 97/462 (20%)
Query: 2 TMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTLL 61
++FE +TR + ++++ GD+ + SL+D RF F LV KR F+G R+ T TL+
Sbjct: 3 SVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRT---FFGCRHYTTGLTLM 59
Query: 62 DVLEP-GSSPSDPTDTGNFGFK------NMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLE 114
D+L+ G D D+G G K + +D+ E V +PK + + G+ + ++
Sbjct: 60 DILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIK 119
Query: 115 VQTLSVAPKALETVQERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEAC 174
+ ++ + L T++ RKL + PF + ENLY+V E +ETV+E TL+ + +
Sbjct: 120 ISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYK-- 177
Query: 175 FSLPFFAPLGLQGSINHK----EAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQT 230
F++ + QG +++K VTIP VL++RV+QL+ K+
Sbjct: 178 ----FWSQIS-QGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKE-------------- 218
Query: 231 FPPGEKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLL 290
+G E R +KE+++ ++ L+ + +L+SL+K L
Sbjct: 219 --------------TMRKSLGS--EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCL 262
Query: 291 GKKKELQDLELALEGALDKGHEVTLEALPKDVL---------LSKEAVGAILYFVGALTE 341
GK+ QDLE + L G E+ +E K +L L + AIL F+ AL E
Sbjct: 263 GKEDIRQDLEQRVSEVLISG-ELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLE 321
Query: 342 LSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTE 401
LSE QQ + +++EK LP+ V+S MEQN+
Sbjct: 322 LSEEQQ-FVAEALEKGTLPLLKDQVKSVMEQNW--------------------------- 353
Query: 402 ALVGLSGLEVQRSGPQYMWDPDTLPRLCALYAGLSLLQQLTK 443
E+ S P +DP+ LCALY +S+L +L +
Sbjct: 354 -------DELASSPPDMDYDPEA-RILCALYVVVSILLELAE 387
>gi|111607457 deafness, autosomal recessive 59 [Homo sapiens]
Length = 352
Score = 63.2 bits (152), Expect = 5e-10
Identities = 57/225 (25%), Positives = 101/225 (44%), Gaps = 24/225 (10%)
Query: 3 MFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTLLD 62
MF T++ +Q+ G L P+ SL + ++ P LV++K++ LF ++ T +TL D
Sbjct: 1 MFAAATKSFVKQVGDGGRLVPVPSLSEADKYQPLSLVVKKKRCFLFPRYKFTSTPFTLKD 60
Query: 63 VL------EPGSSP------SDPTDTGNFGFK-NMLDTRVEGDVDVPKTVKVKGTAGLSQ 109
+L G S D +D +G + N + V +V ++ VK + G+
Sbjct: 61 ILLGDREISAGISSYQLLNYEDESDVSLYGRRGNHIVNDVGINVAGSDSIAVKASFGIVT 120
Query: 110 NSTLEVQTLSVAPKALETVQERKLAADHPFLKEMQDQGEN-LYVVMEVVETVQEVTLE-R 167
+EV TL L+ + RK+ DH +++ + + L VVME + T ++ +L
Sbjct: 121 KHEVEVSTL------LKEITTRKINFDHSLIRQSRSSRKAVLCVVMESIRTTRQCSLSVH 174
Query: 168 AGKAEACFSLPFFAPLGLQGSINHKEAVTIPKGCVLAFRVRQLMV 212
AG F + Q +A+ P +AF V +L +
Sbjct: 175 AGIRGEAMRFHF---MDEQNPKGRDKAIVFPAHTTIAFSVFELFI 216
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 40.8 bits (94), Expect = 0.003
Identities = 46/188 (24%), Positives = 89/188 (47%), Gaps = 22/188 (11%)
Query: 235 EKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKK 294
+K + ++LIQ ++ + + L EE + + Q+E+ +++ +L S+ K K
Sbjct: 263 DKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTK 322
Query: 295 ELQDLELALEGAL--DKGHEVTLEALPKDVLL-----------SKEAVGAILYFVG---- 337
EL+D++++L+ ++ K E L+ K + S +A A + V
Sbjct: 323 ELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFET 382
Query: 338 ---ALTELSEAQQKLLVKSMEK-KILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLG 393
+L EL +Q+ L K+ ++ KIL ++L+ S +E+ L L+ EL LG
Sbjct: 383 TVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELE-ELKKVLG 441
Query: 394 DEELTLTE 401
++E L E
Sbjct: 442 EKETLLYE 449
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 37.4 bits (85), Expect = 0.028
Identities = 38/142 (26%), Positives = 59/142 (41%), Gaps = 20/142 (14%)
Query: 257 FRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLEL----------ALEGA 306
F+ L EE ++ E+ ++ + S ++L KKKEL+ + L ALE
Sbjct: 1569 FQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDR 1628
Query: 307 LDKGHEVTLEALP----------KDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEK 356
L+ L L K LLS+ Y G + LSE KL + E
Sbjct: 1629 LESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREV 1688
Query: 357 KILPVQLKLVESTMEQNFLLDK 378
IL +LK VES+ + ++ +
Sbjct: 1689 HILEEKLKSVESSQSETLIVPR 1710
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
sapiens]
Length = 2564
Score = 37.0 bits (84), Expect = 0.036
Identities = 52/231 (22%), Positives = 91/231 (39%), Gaps = 23/231 (9%)
Query: 192 KEAVT--IPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQTFPPGEKSGEEKVILIQASD 249
+EAVT + K R +Q M K D+ ++ H D + + EK+++ +
Sbjct: 1277 QEAVTRLLEKNQENQLRAQQWMQKLHDQLELQHFLRDCHEL----DGWIHEKMLMARDGT 1332
Query: 250 VGDVHE------GFRTLKEEVQRETQQVEKLSRVGQS------SLLSSLSKLLGKKKELQ 297
D H+ + E+ + + +EK+ R GQ L +S+ K LG E++
Sbjct: 1333 REDNHKLHKRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLG---EIR 1389
Query: 298 DLELALEGALDKGHEVTLEALPKDVLLSK--EAVGAILYFVGALTELSEAQQKLLVKSME 355
LE EA D L+ E +L+ L ++ V S
Sbjct: 1390 QCWAELESTTQAKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDLATVNSQL 1449
Query: 356 KKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTEALVGL 406
KK+ ++ ++ E E L + PL+P +G+ + + E LV L
Sbjct: 1450 KKLQSMESQVEEWYREVGELQAQTAALPLEPASKELVGERQNAVGERLVRL 1500
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 33.9 bits (76), Expect = 0.31
Identities = 48/227 (21%), Positives = 92/227 (40%), Gaps = 14/227 (6%)
Query: 202 VLAFRVRQLMVKGKDEWDIPHICNDNMQTFPPGEKSGEEKVILIQASDVGDVHEGFRTLK 261
V A V Q+ ++ E+ C DN E++ + + ++ ++G
Sbjct: 2551 VAAALVSQIQLEAVQEY--AKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRI 2608
Query: 262 EEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLELALEGALDKGHEVTLEALPKD 321
E++ + ++ + + + + +L K+K+L +L+ LEG K E + P+D
Sbjct: 2609 SELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQD 2668
Query: 322 VLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGV 381
V + K L+ + + L +S+ K K +++ L+ + +
Sbjct: 2669 VEVLKTTTE--LFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKETNM 2726
Query: 382 FPLQPELLSSLGDEELTLTEALVGLSGL------EVQRSGPQYMWDP 422
LQ + LS + D L EA LS L EVQ S M++P
Sbjct: 2727 TSLQKD-LSQVRDH---LAEAKEKLSILEKEDETEVQESKKACMFEP 2769
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 33.9 bits (76), Expect = 0.31
Identities = 48/227 (21%), Positives = 92/227 (40%), Gaps = 14/227 (6%)
Query: 202 VLAFRVRQLMVKGKDEWDIPHICNDNMQTFPPGEKSGEEKVILIQASDVGDVHEGFRTLK 261
V A V Q+ ++ E+ C DN E++ + + ++ ++G
Sbjct: 2543 VAAALVSQIQLEAVQEY--AKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRI 2600
Query: 262 EEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLELALEGALDKGHEVTLEALPKD 321
E++ + ++ + + + + +L K+K+L +L+ LEG K E + P+D
Sbjct: 2601 SELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQD 2660
Query: 322 VLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGV 381
V + K L+ + + L +S+ K K +++ L+ + +
Sbjct: 2661 VEVLKTTTE--LFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVKETNM 2718
Query: 382 FPLQPELLSSLGDEELTLTEALVGLSGL------EVQRSGPQYMWDP 422
LQ + LS + D L EA LS L EVQ S M++P
Sbjct: 2719 TSLQKD-LSQVRDH---LAEAKEKLSILEKEDETEVQESKKACMFEP 2761
>gi|115430239 spectrin, beta, non-erythrocytic 4 isoform sigma5
[Homo sapiens]
Length = 678
Score = 33.9 bits (76), Expect = 0.31
Identities = 38/161 (23%), Positives = 64/161 (39%), Gaps = 14/161 (8%)
Query: 254 HEGFRTLKEEVQRETQQVEKLSRVGQS------SLLSSLSKLLGKKKELQDLELALEGAL 307
H+ F E+ + + +EK+ R GQ L +S+ K LG E++ LE
Sbjct: 22 HQAFMA---ELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLG---EIRQCWAELESTT 75
Query: 308 DKGHEVTLEALPKDVLLSK--EAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLKL 365
EA D L+ E +L+ L ++ V S KK+ ++ ++
Sbjct: 76 QAKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQV 135
Query: 366 VESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTEALVGL 406
E E L + PL+P +G+ + + E LV L
Sbjct: 136 EEWYREVGELQAQTAALPLEPASKELVGERQNAVGERLVRL 176
>gi|169168964 PREDICTED: hypothetical protein LOC100131031 [Homo
sapiens]
Length = 252
Score = 33.5 bits (75), Expect = 0.40
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Query: 213 KGKDEWDIPHICNDNMQTFPPGEKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVE 272
KGK + +I ND++Q K + + D+ LK ++++E Q E
Sbjct: 147 KGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKE 206
Query: 273 KLSRVGQS---SLLSSLSKLLGKKKELQDLELALEGALD 308
+L +S L +++S+ K +DLELAL+ A D
Sbjct: 207 RLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQD 245
>gi|169168628 PREDICTED: hypothetical protein LOC100131031 [Homo
sapiens]
Length = 252
Score = 33.5 bits (75), Expect = 0.40
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Query: 213 KGKDEWDIPHICNDNMQTFPPGEKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVE 272
KGK + +I ND++Q K + + D+ LK ++++E Q E
Sbjct: 147 KGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKE 206
Query: 273 KLSRVGQS---SLLSSLSKLLGKKKELQDLELALEGALD 308
+L +S L +++S+ K +DLELAL+ A D
Sbjct: 207 RLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQD 245
>gi|169169551 PREDICTED: hypothetical protein LOC100131031 [Homo
sapiens]
Length = 252
Score = 33.5 bits (75), Expect = 0.40
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Query: 213 KGKDEWDIPHICNDNMQTFPPGEKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVE 272
KGK + +I ND++Q K + + D+ LK ++++E Q E
Sbjct: 147 KGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKE 206
Query: 273 KLSRVGQS---SLLSSLSKLLGKKKELQDLELALEGALD 308
+L +S L +++S+ K +DLELAL+ A D
Sbjct: 207 RLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQD 245
>gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13
[Homo sapiens]
Length = 5058
Score = 32.3 bits (72), Expect = 0.89
Identities = 14/55 (25%), Positives = 31/55 (56%)
Query: 126 ETVQERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEACFSLPFF 180
+T + K + FLKE+QD E ++ +M+ + ++ + +ER+ ++ + FF
Sbjct: 101 QTAADPKKVNNLAFLKEIQDLAEEIHGMMDKAKNLKRLWVERSNTPDSSYGSSFF 155
>gi|4506975 solute carrier family 12 (sodium/potassium/chloride
transporters), member 2 [Homo sapiens]
Length = 1212
Score = 32.3 bits (72), Expect = 0.89
Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 23/125 (18%)
Query: 278 GQSSLLSSLSKLLGKKKELQDLELALEGALDKGHEVTLEALPKDV-----------LLSK 326
GQ LLSS K G K + +E + + LD ++ + + V LL K
Sbjct: 933 GQEELLSSQEKSPGTKDVVVSVEYSKKSDLDTSKPLSEKPITHKVEEEDGKTATQPLLKK 992
Query: 327 EAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQP 386
E+ G I+ L+ A QKLL S + Q K ++T++ +L D G+ L P
Sbjct: 993 ESKGPIV-------PLNVADQKLLEASTQ-----FQKKQGKNTIDVWWLFDDGGLTLLIP 1040
Query: 387 ELLSS 391
LL++
Sbjct: 1041 YLLTT 1045
>gi|68299759 ecotropic viral integration site 5 [Homo sapiens]
Length = 810
Score = 32.3 bits (72), Expect = 0.89
Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 11/79 (13%)
Query: 342 LSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTE 401
LSEA+ + +K M+ K+L ++ + N L D+ + LQ EL++ +L E
Sbjct: 472 LSEAESQCALKEMQDKVLDIEKR-------NNSLPDENNIARLQEELIA----VKLREAE 520
Query: 402 ALVGLSGLEVQRSGPQYMW 420
A++GL L Q + W
Sbjct: 521 AIMGLKELRQQVKDLEEHW 539
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 32.0 bits (71), Expect = 1.2
Identities = 32/156 (20%), Positives = 71/156 (45%), Gaps = 4/156 (2%)
Query: 236 KSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKE 295
K G + + + S+ G E + ++RE + E V Q L ++ ++E
Sbjct: 1175 KEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERE 1234
Query: 296 LQDLELALEGALDKGHEVTLEALP--KDVLLSKEAVGAILYFVGALTELSEAQQKLLVKS 353
LQ+L+ +L +K +VT + + ++++ E + ++ L E E ++ L +
Sbjct: 1235 LQELQDSLNAEREK-VQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDL-QQ 1292
Query: 354 MEKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELL 389
M+ K+ ++L ++ L +K G+ + +LL
Sbjct: 1293 MQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLL 1328
Score = 31.2 bits (69), Expect = 2.0
Identities = 50/204 (24%), Positives = 85/204 (41%), Gaps = 31/204 (15%)
Query: 228 MQTFPPGEKSGEEKVILIQASDVGDV---HEGFRT---------------LKEEVQRETQ 269
+ P ++ EK + Q S++ + HE F+ +E + ET+
Sbjct: 14 LNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETR 73
Query: 270 QVEKLSRVGQSSLLSSLSKLLGKKKEL---QDLELALEGALDKGHEVTLEALPKDVLLSK 326
+ + L R+ L + L L K KEL QD +A++ + E LEA +D++ +
Sbjct: 74 ECQSL-RLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKE-ELEAEKRDLIRTN 131
Query: 327 EAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQP 386
E + L ++ ++ +KL + K L QLKL E + +E +
Sbjct: 132 ERLSQELEYL--TEDVKRLNEKLKESNTTKGEL--QLKLDELQASDVSVKYREKRLEQEK 187
Query: 387 ELLSS----LGDEELTLTEALVGL 406
ELL S L E T T+ L+ L
Sbjct: 188 ELLHSQNTWLNTELKTKTDELLAL 211
>gi|50086624 integrator complex subunit 4 [Homo sapiens]
Length = 963
Score = 31.6 bits (70), Expect = 1.5
Identities = 46/164 (28%), Positives = 72/164 (43%), Gaps = 32/164 (19%)
Query: 276 RVGQSSLLSSLSKLLGKKKE--LQDLELALEGALDKGHEVTLEALPKDVLLSKEAVGAIL 333
R+ +SLL LSK G + + D L+ +K H+V + L D LL A+G
Sbjct: 89 RLKIASLLGLLSKTAGFSPDCIMDDAINILQN--EKSHQVLAQLL--DTLL---AIG--- 138
Query: 334 YFVGALTELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLG 393
T+L E Q +++ +++ V K + T GV +LL +LG
Sbjct: 139 ------TKLPENQ------AIQMRLVDVACKHLTDT--------SHGVRNKCLQLLGNLG 178
Query: 394 DEELTLTEALVGLSGLEVQRSGPQYMWDPDTLPRLCALYAGLSL 437
E ++T+ GL+ +VQ+ Y D D R A+ A L L
Sbjct: 179 SLEKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQL 222
>gi|19923193 heat shock 70kD protein binding protein [Homo sapiens]
Length = 369
Score = 31.6 bits (70), Expect = 1.5
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 13/107 (12%)
Query: 340 TELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFL-LDKEGVFPLQPELLSSLGDEELT 398
T+ +++++ + + K + LK E + E++ L +DKEGV + +GDE
Sbjct: 46 TQKAKSEENTKEEKPDSKKVEEDLKADEPSSEESDLEIDKEGVIEPDTDAPQEMGDENAE 105
Query: 399 LTE------------ALVGLSGLEVQRSGPQYMWDPDTLPRLCALYA 433
+TE A+ L+ E+Q++ + PRL LYA
Sbjct: 106 ITEEMMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYA 152
>gi|100814339 coiled-coil domain containing 146 [Homo sapiens]
Length = 955
Score = 31.6 bits (70), Expect = 1.5
Identities = 39/157 (24%), Positives = 75/157 (47%), Gaps = 28/157 (17%)
Query: 239 EEKVILIQASDV----GDVHEGFRTLKE---EVQRETQQVEKLSRVGQSSLLSSLSKLLG 291
EEK+I+++ + G++ + + L+E E+++E Q + + + L S +LL
Sbjct: 153 EEKIIIVKEFEKITKPGEMEKKMKILRESTEELRKEIMQKKLEIKNLREDLASKQKQLLK 212
Query: 292 KKKELQDLELALEGALDKGHEVTLEALPKDVLLSKEAVGA-ILYFVGALTELS-EAQQKL 349
++KEL++L GH+V L KD + + + I + +T E ++K
Sbjct: 213 EQKELEEL---------LGHQVVL----KDEVAHHQTIPVQIGKEIEKITRKKVEMEKKK 259
Query: 350 LVKSMEKKILPVQLKLVESTM------EQNFLLDKEG 380
+V E K L LK VE+ + ++N + + EG
Sbjct: 260 IVLEQEVKTLNDSLKKVENKVSAIVDEKENVIKEVEG 296
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 31.2 bits (69), Expect = 2.0
Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 17/139 (12%)
Query: 260 LKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLELALEGALDKGHEVTLEALP 319
L EE+ + + +K + + SL S +L K++EL+D++ L K L+AL
Sbjct: 601 LAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM--NFLLKAEVQKLQALA 658
Query: 320 KDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLK-LVESTMEQ-NFLLD 377
+ A EL + QQ + VK + ++L QL+ + + ME+ L D
Sbjct: 659 NEQ-------------AAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND 705
Query: 378 KEGVFPLQPELLSSLGDEE 396
+ + + L +L E+
Sbjct: 706 QNKALKSEVQKLQTLVSEQ 724
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 31.2 bits (69), Expect = 2.0
Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 17/139 (12%)
Query: 260 LKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLELALEGALDKGHEVTLEALP 319
L EE+ + + +K + + SL S +L K++EL+D++ L K L+AL
Sbjct: 601 LAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM--NFLLKAEVQKLQALA 658
Query: 320 KDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLK-LVESTMEQ-NFLLD 377
+ A EL + QQ + VK + ++L QL+ + + ME+ L D
Sbjct: 659 NEQ-------------AAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND 705
Query: 378 KEGVFPLQPELLSSLGDEE 396
+ + + L +L E+
Sbjct: 706 QNKALKSEVQKLQTLVSEQ 724
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 31.2 bits (69), Expect = 2.0
Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 17/139 (12%)
Query: 260 LKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLELALEGALDKGHEVTLEALP 319
L EE+ + + +K + + SL S +L K++EL+D++ L K L+AL
Sbjct: 601 LAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM--NFLLKAEVQKLQALA 658
Query: 320 KDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLK-LVESTMEQ-NFLLD 377
+ A EL + QQ + VK + ++L QL+ + + ME+ L D
Sbjct: 659 NEQ-------------AAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND 705
Query: 378 KEGVFPLQPELLSSLGDEE 396
+ + + L +L E+
Sbjct: 706 QNKALKSEVQKLQTLVSEQ 724
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 31.2 bits (69), Expect = 2.0
Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 17/139 (12%)
Query: 260 LKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLELALEGALDKGHEVTLEALP 319
L EE+ + + +K + + SL S +L K++EL+D++ L K L+AL
Sbjct: 601 LAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM--NFLLKAEVQKLQALA 658
Query: 320 KDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLK-LVESTMEQ-NFLLD 377
+ A EL + QQ + VK + ++L QL+ + + ME+ L D
Sbjct: 659 NEQ-------------AAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILND 705
Query: 378 KEGVFPLQPELLSSLGDEE 396
+ + + L +L E+
Sbjct: 706 QNKALKSEVQKLQTLVSEQ 724
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
sapiens]
Length = 2346
Score = 31.2 bits (69), Expect = 2.0
Identities = 49/211 (23%), Positives = 84/211 (39%), Gaps = 20/211 (9%)
Query: 204 AFRVRQLMVKGKDEWDIPHICNDNMQTFPPGEKSGE------EKVILIQASDVGDVHEGF 257
A Q +VK E + + N PP G+ E+++ ++A + E
Sbjct: 962 AHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSNRCLQEEMLHLRAEFHQHLEEK- 1020
Query: 258 RTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLELALEGALDKGHEVTLEA 317
R +EE++ Q+E+ G SS+ + +L E +L+ + A+ G E+ +
Sbjct: 1021 RKAEEELKELKAQIEE---AGFSSVSHIRNTMLSLCLENAELKEQMGEAMSDGWEIEED- 1076
Query: 318 LPKDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLD 377
KE ++ V LSE+ + + ++ K+ ++ EQ L
Sbjct: 1077 --------KEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAH-NIINLLKEQLVLSS 1127
Query: 378 KEGVFPLQPELLSSLGDEELTLTEALVGLSG 408
KEG L PELL L + LVG G
Sbjct: 1128 KEGNSKLTPELLVHLTSTIERINTELVGSPG 1158
>gi|7661788 mediator complex subunit 4 [Homo sapiens]
Length = 270
Score = 31.2 bits (69), Expect = 2.0
Identities = 15/72 (20%), Positives = 40/72 (55%)
Query: 236 KSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKE 295
+ GE + ++ A + G +H + L++EV++ +++L + + + + + K++
Sbjct: 72 RDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEK 131
Query: 296 LQDLELALEGAL 307
L+ +E A +GA+
Sbjct: 132 LKSIEKARKGAI 143
>gi|19923403 exosome component 2 [Homo sapiens]
Length = 293
Score = 31.2 bits (69), Expect = 2.0
Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 4/69 (5%)
Query: 249 DVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGK-KKELQDLELALEGAL 307
+VGD+ G T EVQ++ +VE SR+ LLSS++ G+ ++ + ELA+ G L
Sbjct: 79 EVGDIVVGRIT---EVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFL 135
Query: 308 DKGHEVTLE 316
+G ++ E
Sbjct: 136 QEGDLISAE 144
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 30.8 bits (68), Expect = 2.6
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 20/147 (13%)
Query: 243 ILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQD---- 298
++ ASDV ++ + L V+ +++ R+ LL+ L K KK+ L +
Sbjct: 1417 LVAMASDVEGLYAAVKALVCVVKSNPLASKEMERIKGYQLLAMLLK---KKRSLLNSHIL 1473
Query: 299 -LELALEGALDKGHEVTL---EALPKDVLLSKEA---------VGAILYFVGALTELSEA 345
L +L G +D GHE ++ +D+L E + +F+ LTE SEA
Sbjct: 1474 HLTFSLVGTVDSGHETSIIPNSTAFQDLLCDFEVWLHAPYELHLSLFEHFIELLTESSEA 1533
Query: 346 QQKLLVKSMEKKILPVQLKLVESTMEQ 372
+ + + I + L L + ++ Q
Sbjct: 1534 SKNAKLMREFQLIPKLLLTLRDMSLSQ 1560
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,874,031
Number of Sequences: 37866
Number of extensions: 692467
Number of successful extensions: 2307
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 2240
Number of HSP's gapped (non-prelim): 102
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.