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Search of human proteins with 150378539
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150378539 piccolo isoform 1 [Homo sapiens]
(5142 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150378539 piccolo isoform 1 [Homo sapiens] 1.019e+04 0.0
gi|150170670 piccolo isoform 2 [Homo sapiens] 9770 0.0
gi|91208420 bassoon protein [Homo sapiens] 737 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 221 2e-56
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 176 5e-43
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 176 5e-43
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 176 5e-43
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 176 5e-43
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 158 2e-37
gi|110349719 titin isoform N2-A [Homo sapiens] 156 6e-37
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 150 2e-35
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 145 8e-34
gi|154354983 regulating synaptic membrane exocytosis 2 isoform a... 143 4e-33
gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapi... 141 2e-32
gi|116284392 mucin 2 precursor [Homo sapiens] 139 9e-32
gi|154354981 regulating synaptic membrane exocytosis 2 isoform b... 137 3e-31
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 135 1e-30
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 134 2e-30
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 132 1e-29
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 125 8e-28
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 125 1e-27
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 124 2e-27
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 123 5e-27
gi|47132519 Ras association and pleckstrin homology domains 1 is... 123 5e-27
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 122 9e-27
gi|91982772 mucin 17 [Homo sapiens] 119 6e-26
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 117 3e-25
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 116 5e-25
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 116 5e-25
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 112 9e-24
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 1.019e+04 bits (26451), Expect = 0.0
Identities = 5142/5142 (100%), Positives = 5142/5142 (100%)
Query: 1 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM 60
MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM
Sbjct: 1 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM 60
Query: 61 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR 120
SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR
Sbjct: 61 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR 120
Query: 121 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180
SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS
Sbjct: 121 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180
Query: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240
DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240
Query: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS 300
SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS 300
Query: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360
PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360
Query: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480
LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480
Query: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS 540
PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS 540
Query: 541 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH 600
AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH
Sbjct: 541 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH 600
Query: 601 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660
VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK
Sbjct: 601 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660
Query: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA 720
LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA
Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA 720
Query: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS
Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Query: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840
SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES
Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840
Query: 841 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE
Sbjct: 841 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Query: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP
Sbjct: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR 1020
GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR 1020
Query: 1021 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT 1080
TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT
Sbjct: 1021 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT 1080
Query: 1081 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP 1140
ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP
Sbjct: 1081 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP 1140
Query: 1141 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL 1200
TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL
Sbjct: 1141 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL 1200
Query: 1201 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ 1260
EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ
Sbjct: 1201 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ 1260
Query: 1261 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ 1320
KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ
Sbjct: 1261 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ 1320
Query: 1321 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL 1380
PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL
Sbjct: 1321 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL 1380
Query: 1381 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE 1440
IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE
Sbjct: 1381 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE 1440
Query: 1441 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV 1500
VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV
Sbjct: 1441 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV 1500
Query: 1501 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI 1560
DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI
Sbjct: 1501 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI 1560
Query: 1561 IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID 1620
IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID
Sbjct: 1561 IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID 1620
Query: 1621 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY 1680
EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY
Sbjct: 1621 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY 1680
Query: 1681 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED 1740
SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED
Sbjct: 1681 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED 1740
Query: 1741 SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR 1800
SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR
Sbjct: 1741 SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR 1800
Query: 1801 KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS 1860
KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
Sbjct: 1801 KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS 1860
Query: 1861 PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE 1920
PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE
Sbjct: 1861 PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE 1920
Query: 1921 MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE 1980
MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE
Sbjct: 1921 MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE 1980
Query: 1981 NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH 2040
NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH
Sbjct: 1981 NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH 2040
Query: 2041 EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR 2100
EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR
Sbjct: 2041 EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR 2100
Query: 2101 MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE 2160
MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE
Sbjct: 2101 MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE 2160
Query: 2161 SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF 2220
SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF
Sbjct: 2161 SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF 2220
Query: 2221 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK 2280
EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK
Sbjct: 2221 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK 2280
Query: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF 2340
PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF
Sbjct: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF 2340
Query: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD
Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
Query: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460
ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460
Query: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520
TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP
Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520
Query: 2521 TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY 2580
TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY
Sbjct: 2521 TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY 2580
Query: 2581 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY 2640
VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY
Sbjct: 2581 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY 2640
Query: 2641 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP 2700
ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP
Sbjct: 2641 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP 2700
Query: 2701 EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA 2760
EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA
Sbjct: 2701 EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA 2760
Query: 2761 NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAM 2820
NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAM
Sbjct: 2761 NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAM 2820
Query: 2821 TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT 2880
TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT
Sbjct: 2821 TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT 2880
Query: 2881 NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVC 2940
NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVC
Sbjct: 2881 NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVC 2940
Query: 2941 CDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLA 3000
CDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLA
Sbjct: 2941 CDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLA 3000
Query: 3001 EAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIST 3060
EAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIST
Sbjct: 3001 EAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIST 3060
Query: 3061 PQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLSG 3120
PQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLSG
Sbjct: 3061 PQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLSG 3120
Query: 3121 IHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETIDS 3180
IHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETIDS
Sbjct: 3121 IHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETIDS 3180
Query: 3181 VPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQ 3240
VPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQ
Sbjct: 3181 VPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQ 3240
Query: 3241 EIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQ 3300
EIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQ
Sbjct: 3241 EIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQ 3300
Query: 3301 QQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTAS 3360
QQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTAS
Sbjct: 3301 QQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTAS 3360
Query: 3361 AVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVR 3420
AVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVR
Sbjct: 3361 AVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVR 3420
Query: 3421 GQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQD 3480
GQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQD
Sbjct: 3421 GQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQD 3480
Query: 3481 EWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIR 3540
EWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIR
Sbjct: 3481 EWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIR 3540
Query: 3541 ARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGY 3600
ARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGY
Sbjct: 3541 ARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGY 3600
Query: 3601 SSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPD 3660
SSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPD
Sbjct: 3601 SSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPD 3660
Query: 3661 MAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKV 3720
MAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKV
Sbjct: 3661 MAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKV 3720
Query: 3721 KRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKL 3780
KRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKL
Sbjct: 3721 KRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKL 3780
Query: 3781 RKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVS 3840
RKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVS
Sbjct: 3781 RKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVS 3840
Query: 3841 STRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAP 3900
STRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAP
Sbjct: 3841 STRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAP 3900
Query: 3901 TSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQ 3960
TSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQ
Sbjct: 3901 TSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQ 3960
Query: 3961 QKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERSS 4020
QKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERSS
Sbjct: 3961 QKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERSS 4020
Query: 4021 MASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLL 4080
MASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLL
Sbjct: 4021 MASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLL 4080
Query: 4081 RTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESLD 4140
RTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESLD
Sbjct: 4081 RTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESLD 4140
Query: 4141 HLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKM 4200
HLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKM
Sbjct: 4141 HLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKM 4200
Query: 4201 SKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSL 4260
SKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSL
Sbjct: 4201 SKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSL 4260
Query: 4261 GTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQE 4320
GTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQE
Sbjct: 4261 GTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQE 4320
Query: 4321 AEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGP 4380
AEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGP
Sbjct: 4321 AEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGP 4380
Query: 4381 LPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRRE 4440
LPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRRE
Sbjct: 4381 LPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRRE 4440
Query: 4441 ETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKIT 4500
ETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKIT
Sbjct: 4441 ETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKIT 4500
Query: 4501 RDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNG 4560
RDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNG
Sbjct: 4501 RDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNG 4560
Query: 4561 IPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGVD 4620
IPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGVD
Sbjct: 4561 IPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGVD 4620
Query: 4621 PKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHGS 4680
PKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHGS
Sbjct: 4621 PKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHGS 4680
Query: 4681 SKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGR 4740
SKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGR
Sbjct: 4681 SKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGR 4740
Query: 4741 GQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSN 4800
GQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSN
Sbjct: 4741 GQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSN 4800
Query: 4801 DFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIF 4860
DFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIF
Sbjct: 4801 DFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIF 4860
Query: 4861 PDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAE 4920
PDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAE
Sbjct: 4861 PDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAE 4920
Query: 4921 AAVQQLRIQPTKPPNHRPAESSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPIPRIGK 4980
AAVQQLRIQPTKPPNHRPAESSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPIPRIGK
Sbjct: 4921 AAVQQLRIQPTKPPNHRPAESSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPIPRIGK 4980
Query: 4981 MGQNGQEPVKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEILQCRNITYKF 5040
MGQNGQEPVKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEILQCRNITYKF
Sbjct: 4981 MGQNGQEPVKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEILQCRNITYKF 5040
Query: 5041 KSPDHLPDLYVKIYVMNISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILLF 5100
KSPDHLPDLYVKIYVMNISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILLF
Sbjct: 5041 KSPDHLPDLYVKIYVMNISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILLF 5100
Query: 5101 SNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKLLVSPTQTH 5142
SNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKLLVSPTQTH
Sbjct: 5101 SNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKLLVSPTQTH 5142
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 9770 bits (25353), Expect = 0.0
Identities = 4931/4932 (99%), Positives = 4932/4932 (100%)
Query: 1 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM 60
MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM
Sbjct: 1 MGNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVM 60
Query: 61 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR 120
SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR
Sbjct: 61 SRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR 120
Query: 121 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180
SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS
Sbjct: 121 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180
Query: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240
DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSIS 240
Query: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS 300
SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS
Sbjct: 241 SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS 300
Query: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360
PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360
Query: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480
LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480
Query: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS 540
PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS
Sbjct: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS 540
Query: 541 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH 600
AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH
Sbjct: 541 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH 600
Query: 601 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660
VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK
Sbjct: 601 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660
Query: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA 720
LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA
Sbjct: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA 720
Query: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS
Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Query: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840
SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES
Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840
Query: 841 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE
Sbjct: 841 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Query: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP
Sbjct: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
Query: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR 1020
GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR 1020
Query: 1021 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT 1080
TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT
Sbjct: 1021 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCT 1080
Query: 1081 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP 1140
ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP
Sbjct: 1081 ECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVP 1140
Query: 1141 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL 1200
TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL
Sbjct: 1141 TESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL 1200
Query: 1201 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ 1260
EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ
Sbjct: 1201 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQ 1260
Query: 1261 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ 1320
KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ
Sbjct: 1261 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ 1320
Query: 1321 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL 1380
PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL
Sbjct: 1321 PQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL 1380
Query: 1381 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE 1440
IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE
Sbjct: 1381 IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHE 1440
Query: 1441 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV 1500
VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV
Sbjct: 1441 VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFV 1500
Query: 1501 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI 1560
DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI
Sbjct: 1501 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI 1560
Query: 1561 IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID 1620
IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID
Sbjct: 1561 IEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSID 1620
Query: 1621 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY 1680
EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY
Sbjct: 1621 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKY 1680
Query: 1681 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED 1740
SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED
Sbjct: 1681 SAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDED 1740
Query: 1741 SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR 1800
SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR
Sbjct: 1741 SDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQR 1800
Query: 1801 KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS 1860
KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS
Sbjct: 1801 KSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS 1860
Query: 1861 PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE 1920
PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE
Sbjct: 1861 PSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEE 1920
Query: 1921 MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE 1980
MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE
Sbjct: 1921 MMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEE 1980
Query: 1981 NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH 2040
NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH
Sbjct: 1981 NGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESH 2040
Query: 2041 EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR 2100
EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR
Sbjct: 2041 EIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDR 2100
Query: 2101 MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE 2160
MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE
Sbjct: 2101 MPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHE 2160
Query: 2161 SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF 2220
SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF
Sbjct: 2161 SLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKF 2220
Query: 2221 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK 2280
EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK
Sbjct: 2221 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK 2280
Query: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF 2340
PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF
Sbjct: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF 2340
Query: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD
Sbjct: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
Query: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460
ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460
Query: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520
TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP
Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP 2520
Query: 2521 TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY 2580
TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY
Sbjct: 2521 TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETY 2580
Query: 2581 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY 2640
VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY
Sbjct: 2581 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY 2640
Query: 2641 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP 2700
ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP
Sbjct: 2641 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP 2700
Query: 2701 EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA 2760
EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA
Sbjct: 2701 EPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITA 2760
Query: 2761 NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAM 2820
NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAM
Sbjct: 2761 NEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAM 2820
Query: 2821 TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT 2880
TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT
Sbjct: 2821 TTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVT 2880
Query: 2881 NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVC 2940
NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVC
Sbjct: 2881 NGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVC 2940
Query: 2941 CDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLA 3000
CDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLA
Sbjct: 2941 CDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLA 3000
Query: 3001 EAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIST 3060
EAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIST
Sbjct: 3001 EAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGAGIST 3060
Query: 3061 PQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLSG 3120
PQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLSG
Sbjct: 3061 PQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRDLSG 3120
Query: 3121 IHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETIDS 3180
IHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETIDS
Sbjct: 3121 IHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAETIDS 3180
Query: 3181 VPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQ 3240
VPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQ
Sbjct: 3181 VPTLTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQ 3240
Query: 3241 EIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQ 3300
EIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQ
Sbjct: 3241 EIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQ 3300
Query: 3301 QQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTAS 3360
QQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTAS
Sbjct: 3301 QQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTAS 3360
Query: 3361 AVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVR 3420
AVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVR
Sbjct: 3361 AVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVR 3420
Query: 3421 GQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQD 3480
GQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQD
Sbjct: 3421 GQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQD 3480
Query: 3481 EWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIR 3540
EWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIR
Sbjct: 3481 EWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIR 3540
Query: 3541 ARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGY 3600
ARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGY
Sbjct: 3541 ARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGY 3600
Query: 3601 SSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPD 3660
SSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPD
Sbjct: 3601 SSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPD 3660
Query: 3661 MAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKV 3720
MAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKV
Sbjct: 3661 MAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKV 3720
Query: 3721 KRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKL 3780
KRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKL
Sbjct: 3721 KRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKL 3780
Query: 3781 RKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVS 3840
RKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVS
Sbjct: 3781 RKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVS 3840
Query: 3841 STRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAP 3900
STRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAP
Sbjct: 3841 STRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAP 3900
Query: 3901 TSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQ 3960
TSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQ
Sbjct: 3901 TSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQ 3960
Query: 3961 QKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERSS 4020
QKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERSS
Sbjct: 3961 QKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERSS 4020
Query: 4021 MASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLL 4080
MASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLL
Sbjct: 4021 MASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLL 4080
Query: 4081 RTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESLD 4140
RTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESLD
Sbjct: 4081 RTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESLD 4140
Query: 4141 HLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKM 4200
HLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKM
Sbjct: 4141 HLAGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKM 4200
Query: 4201 SKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSL 4260
SKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSL
Sbjct: 4201 SKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSL 4260
Query: 4261 GTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQE 4320
GTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQE
Sbjct: 4261 GTGLGTLGNTIRSALQDEADKPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQE 4320
Query: 4321 AEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGP 4380
AEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGP
Sbjct: 4321 AEALDVSFSHASSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGP 4380
Query: 4381 LPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRRE 4440
LPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRRE
Sbjct: 4381 LPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRRE 4440
Query: 4441 ETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKIT 4500
ETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKIT
Sbjct: 4441 ETDWFDKPRESRLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTMHYIFPHARIKIT 4500
Query: 4501 RDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNG 4560
RDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNG
Sbjct: 4501 RDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNG 4560
Query: 4561 IPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGVD 4620
IPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGVD
Sbjct: 4561 IPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGVD 4620
Query: 4621 PKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHGS 4680
PKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHGS
Sbjct: 4621 PKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHGS 4680
Query: 4681 SKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGR 4740
SKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGR
Sbjct: 4681 SKPTDGTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGR 4740
Query: 4741 GQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSN 4800
GQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSN
Sbjct: 4741 GQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSN 4800
Query: 4801 DFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIF 4860
DFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIF
Sbjct: 4801 DFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIF 4860
Query: 4861 PDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAE 4920
PDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAE
Sbjct: 4861 PDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAE 4920
Query: 4921 AAVQQLRIQPTK 4932
AAVQQLRIQP+K
Sbjct: 4921 AAVQQLRIQPSK 4932
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 737 bits (1903), Expect = 0.0
Identities = 551/1505 (36%), Positives = 787/1505 (52%), Gaps = 197/1505 (13%)
Query: 3080 SVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRD------LSGIHTADAVTSL--- 3130
+ +R+++G++YS++ TP +T ITTQP S+ VR SG TA +TSL
Sbjct: 2185 ATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRV 2244
Query: 3131 ----------PAMHHSQPMPRSYFITT-----------------------GASETDIAVT 3157
P + P P + I + G S ++ V
Sbjct: 2245 PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPV- 2303
Query: 3158 GIDISASLQTITMESLTAETIDSVPTLTTASEVFPEVV-GDESALLIVPEEDK------- 3209
G L T T ++ P + + G S L P +K
Sbjct: 2304 GAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQEE 2363
Query: 3210 -----QQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMK 3264
Q+Q L LERE +ELEK++Q R EELE ER E+QR RE+E+++VQ++L+ELQ++K
Sbjct: 2364 RQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIK 2423
Query: 3265 QHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIYQYNYDPSG 3324
H+L QQ+EERQAQF +++E LAQQ+LQLEQIQQLQQQL QQLEEQK RQ + P+
Sbjct: 2424 HHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPF---PAA 2480
Query: 3325 TASPQTTTEQAILEGQYAALEGSQFWATEDATTTASAVVAIEIPQSQGWYTVQSDGVTQY 3384
+P A E + Q+W T +A +A+ P+ G +
Sbjct: 2481 CEAPGRGPPLAAAE----LAQNGQYW----PPLTHAAFIAMAGPEGLG-------QPREP 2525
Query: 3385 IAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVRGQYDDMGE----NMTDDPRSFKKI 3440
+ G+ S+ S D+ ++ E+Q + SG K R + + +P ++I
Sbjct: 2526 VLHRGLPSSAS-----DMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVRRI 2580
Query: 3441 VDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDS 3500
DS VQTDDED R +SRRRR ++S D SVQTDDED EW+ P R RR++R+ ++ DS
Sbjct: 2581 ADSSVQTDDEDGESRYLLSRRRRARRSADCSVQTDDEDSAEWEQPVR-RRRSRLPRHSDS 2639
Query: 3501 MTEA--DKTKPLSK-------VSSIAVQTVAEISVQTEPVGTIR-TPSIR--ARVDAKVE 3548
+++ D T S +SS+ +QT+++ SVQTEP R +P+I A D KVE
Sbjct: 2640 GSDSKHDATASSSSAAATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVE 2699
Query: 3549 IIKHISAPEKTYKGGSLGCQTEADSDTQ---SPQYLSATSPPK----------------D 3589
I+++ISAPEKT +G SL CQTE D Q PQ + T+ +
Sbjct: 2700 IVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFE 2759
Query: 3590 KKRPTPLEIGYSSHLRADSTVQL-APSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLP 3648
KK+P PLEIGY +HL +S QL + PPKSP+VLYSP+SPLSP + L+++F E+
Sbjct: 2760 KKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNK 2819
Query: 3649 DDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGS 3708
+SPQK D A P+ K +QRS+SDPKPLSPTA+ES++ F + GS
Sbjct: 2820 AHVSPQKHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGS 2879
Query: 3709 Q--TMTSSGAQKKVKRTLPNPPPEEIS---TGTQSTFSTMGTVSRRRICRTNTM--ARAK 3761
Q + + +KVKRTLP+PPPEE G S ++ +R + T+ +A
Sbjct: 2880 QVSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKAS 2939
Query: 3762 ILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRER 3821
+L+++DR+L LVE ES KLRKKQAELDEEEKEIDAKL+YLE+GI +RKE+L K+R R+
Sbjct: 2940 LLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDY 2999
Query: 3822 AYLQGVAEDRDYMSDSEVSSTRPTRIESQHG--IERPRTAP-------QTEFSQ--FIPP 3870
L+G+ E RDY+SDSE++ R + G ++ P TA T F Q F PP
Sbjct: 3000 PPLRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPP 3059
Query: 3871 QTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQA 3930
Q + P TQ + + PT S F Y + P QA
Sbjct: 3060 APQYSAGSGGP----TQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPG----LPNQQA 3111
Query: 3931 VATMSFTPQVQPTPTPQPS-YQLPSQMMVIQQKPRQTTLY-LEPKITSNYEVIRNQ--PL 3986
P PT Q + + +P+ QKPRQT+L LE K+ +NYEVI + P+
Sbjct: 3112 FRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPM 3171
Query: 3987 MIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERSSMASSPISSISADSFYADIDHHTPRNY 4046
AP T + G + + +R S++ SP + +DS Y ++ + PRNY
Sbjct: 3172 SSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNY 3231
Query: 4047 VLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLLRTTETRRSQEVTDFLAPLQSSSRLHS 4106
V+IDDI E+TK + STA D + + L + R +E + L +
Sbjct: 3232 VMIDDISELTKDST--STA-----PDSQRLEPLGPGSSGRPGKEPGE-PGVLDGPTLPCC 3283
Query: 4107 YVKAEEDPMEDPYELKLLKHQIKQEFRRGTESLDHLAGLSHYYHADTSYRHFPKSEKYSI 4166
Y + EE+ ED Y+ + ++ G + H Y+ D+ YRH + EKY
Sbjct: 3284 YARGEEESEEDSYDPRGKGGHLRSMESNGRPASTH-------YYGDSDYRHGARVEKYGP 3336
Query: 4167 SRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKMSKFSPIQESRDLEPDYSSYMTSSTSS 4226
+ K +K L A + K+SKH+K ++ K+SKFSPI+E++D+E D +SY + SS
Sbjct: 3337 GPMG-PKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSS 3395
Query: 4227 IGGISSRARLLQDDITFGLRKNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSSG 4286
+ SR R QD+IT+GL+KN+ +QQK+ G S R A++D D+ Y
Sbjct: 3396 --SLVSRGRKFQDEITYGLKKNVYEQQKYYGMS-----------SRDAVED--DRIYGGS 3440
Query: 4287 SRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSARTKPTSLPISQ 4346
SRSR PS+ G LS D S + +E EA++ A KP+SL ++
Sbjct: 3441 SRSR---APSAYSGEKLS-SHDFSGWGKGYE-REREAVE-----RLQKAGPKPSSLSMAH 3490
Query: 4347 SRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMR 4406
SR R P+ +Q SEEESP+SP+G+P R A GPLPP DT QF SSHS+P+VQ+H++
Sbjct: 3491 SRVRPPMRSQASEEESPVSPLGRP----RPAGGPLPP-GGDTCPQFCSSHSMPDVQEHVK 3545
Query: 4407 EESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPRESRLE-----NGHGLDR 4461
+ R Y R+ +I+DD +SDSEAYHL +EETDWFDKPR++R + GH +
Sbjct: 3546 DGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSS 3605
Query: 4462 KLPER 4466
+R
Sbjct: 3606 SSQKR 3610
Score = 583 bits (1504), Expect = e-165
Identities = 566/1914 (29%), Positives = 804/1914 (42%), Gaps = 324/1914 (16%)
Query: 652 PVPS-SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQP 710
PVP P P P +T+ + P Q + PKQ + P + P ++
Sbjct: 59 PVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASP--TPKQASATTPGHESP----RET 112
Query: 711 TLHGSPSAKAKQPP---EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT--D 765
G +A P + DS ++ + + PSV ++ P + Q + +T
Sbjct: 113 RAQGPAGQEADGPRRTLQVDSRTQRSG-RSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCP 171
Query: 766 LVSSSSATTKPDIPSSKVQSQAEEKT------TPPLKTDSAKPSQSFPPTGEKVSPFDSK 819
+ +S T+ P P+ +Q K P K ++ D
Sbjct: 172 ICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMT 231
Query: 820 AIPRPASDSKIIS---HPGPS-----------SESKGQKQVDPVQKKEEPKKAQTKMSPK 865
PR S ++ S P S S+G P ++ E +A + P
Sbjct: 232 TAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPA 291
Query: 866 PDAKPMPKGSPTPPGPRPTAGQTV-PTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ 924
A P G +P P+PT T P P P + + LG+ Q
Sbjct: 292 QAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQT--------Q 343
Query: 925 ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA-PSQPPTSQGPPKST 983
E +TGKLFG GAS+ +QAS L+S QP +Q P AP K P + + PK
Sbjct: 344 EGLTGKLFGLGASLLTQASTLMSV--QPEADTQGQP-APSKGTPKIVFNDASKEAGPKPL 400
Query: 984 GQAP-PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQK 1042
G P P PA P A K EP A P K
Sbjct: 401 GSGPGPGPA-----------PGA-KTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAA 448
Query: 1043 AVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQ 1102
+ K + PK + CPLC+ ELN+GSK P N+NTCT C+ QVCNLCGFNPTPHL E
Sbjct: 449 SKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKT 508
Query: 1103 EWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQ 1162
EWLCLNCQT+R + G LG+ P P+P +S Q
Sbjct: 509 EWLCLNCQTKRLLEGSLGE--------------PTPLPPPTSQQ---------------- 538
Query: 1163 EVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASAL-QEKKPLPEEKKLI 1221
PP+ + S L++ L Q PLP +
Sbjct: 539 -----------------------PPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKAS-- 573
Query: 1222 PEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVA 1281
PL + P P K P+AK E
Sbjct: 574 ------------PLSTKASPLPS--KASPQAKPLRASEPSK------------------T 601
Query: 1282 PKTVQEGK-QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTE 1340
P +VQE K + TK E +P P++ P K+ + +P T V + E
Sbjct: 602 PSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEP-ATPVVKAVPEAPKGGE 660
Query: 1341 KEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQE 1400
ED S +SPQ LSDTGYSSDGISSS EI ++ + + + DS
Sbjct: 661 AEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQL------DSAGVT 714
Query: 1401 SS-PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETL 1459
P SPS++ K+ S++ +L+AQ ++ + E ++P SLS T
Sbjct: 715 GPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRP------HSLSITP 768
Query: 1460 EITISEEEIKESQEERKDTF---KKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEES 1516
E S+EE+++ EE +D+ ++ QQD S D +F + +D VE+S
Sbjct: 769 EAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSD-----DFGSQLR-----HDYVEDS 818
Query: 1517 SESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDE 1576
SE SP+P + + + +EDF+R+QI+EMSA+ED + EDD
Sbjct: 819 SEGGLSPLPPQPPARAAELT---------------DEDFMRRQILEMSAEED-NLEEDDT 862
Query: 1577 FIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEA 1636
+ + + + + + A RRL ++T +E S EA
Sbjct: 863 ATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGS-----AEA 917
Query: 1637 FDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEE 1696
D S L+ GGLRRFKTIELNST + + + Q D E
Sbjct: 918 TDGSGTLQ-----------------GGLRRFKTIELNSTGSYGHELDLGQGPDPS-LDRE 959
Query: 1697 PELEMESLTDSPEDRSRGEGSSSLHAS--SFTPGTSPTSVSSLDEDSDSSPSHKKG--ES 1752
PELEMESLT SPEDRSRGE SS+L AS S+T GTSPTS+SSL+EDSDSSPS ++ E+
Sbjct: 960 PELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEA 1019
Query: 1753 KQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKD 1812
KQQRKARHR HGPLLPTIEDSSEEEELREEEELL+EQEK RE+EQQ+ +S+++K+++DK+
Sbjct: 1020 KQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKE 1079
Query: 1813 ELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEY--SPSIESDPEGF 1870
ELRAQRRRER KTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEY SPS++S+ E
Sbjct: 1080 ELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEAL 1139
Query: 1871 EISPEKIIEVQKVYKLPTAVSLYSPTDEQS-IMQKEGSQKALKSAEEMYEEMMHKTH--K 1927
+ P ++ + Y LPT +SLYSPT+ S S + LKSAEE YEEMM K +
Sbjct: 1140 DGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQ 1199
Query: 1928 YKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQK 1987
+ AA R G + + Y+ + Y + Q
Sbjct: 1200 RQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAA---------------QPA 1244
Query: 1988 GREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESHEIVDLGT 2047
L +YE+ +Q + S+V S E
Sbjct: 1245 AEGTPASLGAAVYEEILQ-------------TSQSIVRMRQASSRDLAFAE--------- 1282
Query: 2048 MVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLT 2107
++E++ L+A++AY + MK+ LTPG+SPTQ
Sbjct: 1283 ---DKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQ----------------------L 1317
Query: 2108 SSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYS 2167
++ +S ++ T S SS IPDV++TQHF+ E + + ++ A + + + +S
Sbjct: 1318 AAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKE--TQDPLKLHSSPASPSSASKEIGMPFS 1375
Query: 2168 E----PSESATSVPPSDTP-SLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFED 2222
+ P+ +A + P+ P + S + S SP +T S T + ++ ED
Sbjct: 1376 QGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPT-TANYGSQTED 1434
Query: 2223 SEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPE 2282
+ S G + + P RA + S SS ES P
Sbjct: 1435 LPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSP- 1493
Query: 2283 GPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDH 2342
G + + + P + G + + T + +
Sbjct: 1494 GKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQE 1553
Query: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKP--RPFFRSSSLD 2400
P VI L + + Q + S SP S +P + +++
Sbjct: 1554 APFMVITL------------ASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPS 1601
Query: 2401 ISAQPPPPPPPPPPPPPPPPPPPPP---------PLPPPTSPKPTILPKKKLTVASPVTT 2451
+S PP PP PP P P P P + + + +P P T
Sbjct: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTP 1661
Query: 2452 ATPLFDAVTTLE-TTAVLRSNGLPVTRICTTAP------PPVPPKPSSIPSGLV 2498
T + D T ++ T +L G+ +T + A P+P + S+ LV
Sbjct: 1662 GTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLV 1715
Score = 224 bits (571), Expect = 2e-57
Identities = 296/1195 (24%), Positives = 451/1195 (37%), Gaps = 142/1195 (11%)
Query: 425 PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484
PG P PGP PG GK P+ AG G+ A + +PGP P P
Sbjct: 18 PGGAGPGPGPGPG------PGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGP 71
Query: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK---PPSQQPGSAKPSA 541
GP + K P + P P+Q P + P T+ P Q+ + +
Sbjct: 72 GPGSTSRRL--DPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTL 129
Query: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHV 601
Q S + S + + VS P P +V A P S T+CP+C T++ L
Sbjct: 130 QVDSRTQRSGRSPS--VSPDRGSTPTSPYSVPQIAPLPSS-----TLCPICKTSD-LTST 181
Query: 602 PEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661
P + NFNTCT+C VC+ CGFNPNPHLT+VKEWLCLNCQM+RALG D+ P S +
Sbjct: 182 PSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQ 241
Query: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS---- 717
+P + + SP K K D ++ P P P +Q + S
Sbjct: 242 LHSPALSPA-----------HSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGP 290
Query: 718 AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD 777
A+A PPE +S P PP +P+ PS + P A + P K T + + AT
Sbjct: 291 AQAAAPPEVGRVS-PQPP-QPTKPSTAEPRPPAGEAP-----AKSATAVPAGLGAT---- 339
Query: 778 IPSSKVQSQAEEKTT-------PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI 830
Q +E T L T ++ P + P SK P+ +
Sbjct: 340 -------EQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFND-A 391
Query: 831 ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK-GSPTPPGPRPTAGQTV 889
GP G K EP +M P +PK G T P Q
Sbjct: 392 SKEAGPKPLGSGPGPGPAPGAKTEP---GARMGPGSGPGALPKTGGTTSPKHGRAEHQAA 448
Query: 890 PTPQQSPKPQEQSR------RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGAS------ 937
PK + R + LN+GS + A + TT + V L GF +
Sbjct: 449 SKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVC-NLCGFNPTPHLVEK 507
Query: 938 -----IFSQASNLI-STAGQ----PGPHSQSGP-GAPMKQAPAPSQPPTSQGPPKSTGQ- 985
+ Q L+ + G+ P P SQ P GAP + A P Q P+ GQ
Sbjct: 508 TEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHR---ASGTSPLKQKGPQGLGQP 564
Query: 986 APPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVL 1045
+ P PAK+ P+ + +P K P QA ++ +E K P +++ K+ +
Sbjct: 565 SGPLPAKASPLSTKA-SPLPSKASP---QAKPLRASEPSKTPSSVQEKKTR--------V 612
Query: 1046 PTKLEKSPK--PEST----CPLCKTELNIGSKDPPNFNTCTECK--NQVCNLCGFNPTPH 1097
PTK E PK PE+T P K+ + P E + +L G +
Sbjct: 613 PTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQD 672
Query: 1098 LTEIQEWLCLNCQTQRAISGQLGDI-----RKMPPAPSGPKASP-MPVPTESSSQKTAVP 1151
+ + L + IS +I +++ S P P P+E +++
Sbjct: 673 ASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMR 732
Query: 1152 PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEK 1211
P ++ E E+ K+ I P ++ E LE+D+ SA E
Sbjct: 733 PLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSA--EW 790
Query: 1212 KPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQI 1271
+ E++ + S+ + +E+ L P+ A E D ++ Q+
Sbjct: 791 RRRREQQDTAESSDDFGSQLRHDYVEDSSEGGL-SPLPPQPPARAAELTDEDFMRRQILE 849
Query: 1272 AEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQ 1331
+ + T G+ G G P+ P+ + K + T ++
Sbjct: 850 MSAEEDNLEEDDTATSGR--GLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEE 907
Query: 1332 VEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL--IPTDEKDIL 1389
+ P E D + L+ TG + G PSL P E + L
Sbjct: 908 LLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESL 967
Query: 1390 KGLKKDSFSQESS----PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQ 1445
G +D E S S+PS + T LS LE + + S + Q E + +Q
Sbjct: 968 TGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDS-----DSSPSRRQRLEEAKQQ 1022
Query: 1446 PKDQEKTQS-LSETLEITISEEEIKESQE--ERKDTFKKDSQQDIPSS--KDHKEKSEFV 1500
K + ++ L T+E + EEE++E +E ++ ++ QQ I S+ K ++K E
Sbjct: 1023 RKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELR 1082
Query: 1501 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGS---SSSDEYKQEDSQGSGEE 1552
R S + SP + ++ + SS EY S S E
Sbjct: 1083 AQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAE 1137
Score = 166 bits (421), Expect = 4e-40
Identities = 175/628 (27%), Positives = 234/628 (37%), Gaps = 116/628 (18%)
Query: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-PAQPSGLTKPLAQQPGTVKPPVQPP 356
L SP+ P +P K P +P E+S+ GP P P T PG + PP
Sbjct: 242 LHSPALSPAH--SPAKQPLGKPDQERSR-GPGGPQPGSRQAETARATSVPGPAQ-AAAPP 297
Query: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416
+ QP P KP + P+ E P A A P G+G T Q G + G
Sbjct: 298 EVGRVSPQPPQPTKPSTAE--PRPPAGEAPAKSATAVPAGLGATEQTQEGLT---GKLFG 352
Query: 417 TPKPLAQQPGLQSPAKAPGPTK-TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475
L Q + T+ P G KI A +++ GP KP PG
Sbjct: 353 LGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDA------SKEAGP-KPLGSGPG 405
Query: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535
PGPA +PG+ P PG+ P+ G+T P + G
Sbjct: 406 --------PGPAPGAKTEPGARMGPGSGPGAL-------------PKTGGTTSP---KHG 441
Query: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595
A+ A + AKP K P + + ICPLC
Sbjct: 442 RAEHQAASKAAAKP---------------------------KTMPKE---RAICPLCQ-A 470
Query: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
EL + AN+NTCT C+ VC+LCGFNP PHL E EWLCLNCQ KR L G L
Sbjct: 471 ELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTP 530
Query: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715
P P + PV S TSP K P Q L +P P P P +
Sbjct: 531 LPPPTSQQPPVGAPHRAS-------GTSPLKQKGP-QGLG---QPSGPLPAKASPLSTKA 579
Query: 716 PSAKAKQPPEADSLSKPAPPKEP-SVPSEQDKAPV-ADDKPKQPKMVKPT--TDLVSSSS 771
+K P+A L P K P SV ++ + P A+ PK P PT T V S
Sbjct: 580 SPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGV 639
Query: 772 ATTKP------DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPA 825
+P +P + +AE+ P D+++ QS TG + S I
Sbjct: 640 RRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTG-----YSSDGISSSQ 694
Query: 826 S-------------DSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872
S DS ++ P P S S ++ V P ++P +KP+
Sbjct: 695 SEITGVVQQEVEQLDSAGVTGPHPPSPS----EIHKVGSSMRPLLQAQGLAPSERSKPLS 750
Query: 873 KGSPTPPGPRPTAGQTVPTPQQSPKPQE 900
G+ RP + P S + E
Sbjct: 751 SGTGEEQKQRPHSLSITPEAFDSDEELE 778
Score = 110 bits (274), Expect = 5e-23
Identities = 189/740 (25%), Positives = 286/740 (38%), Gaps = 151/740 (20%)
Query: 2411 PPPPPPPPPPPPPPPPLPPPTSPKPT---ILPKKKLTVASPVTTATPLFDAVTTLETTAV 2467
P P P P PTS + ++P ++T T PL + ++
Sbjct: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
Query: 2468 LRSNGLPVTR-ICTTAPPPVPPKPSSIPSGLVFTHRP---EPSKPPIAPKPVIPQLPTTT 2523
+ G+P ++ T A V P P+ +P G + P E S P + PTT
Sbjct: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTA 1426
Query: 2524 Q---KPTDIHPKPTGLSLTSSMTLNLVTSA---DYKLPSPTS----------PLSPHSNK 2567
+ D+ P+GL+ SA + P P+ PLSP S
Sbjct: 1427 NYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPS 1486
Query: 2568 SSPRFSKS-----LTETYVVIT--------LPSEPGTPTDSSASQAITSWPLGSPSKDLV 2614
SP FS T + T +P PG PT S T P + LV
Sbjct: 1487 ESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLV 1546
Query: 2615 ----SVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFL 2670
S E F V+ + +S QT + + T +P+ +P+ Q PT+
Sbjct: 1547 WQESSQEAPFMVITLASD-----ASSQTRMVHASAST---SPLCSPTETQ--PTTHGYSQ 1596
Query: 2671 TTEVSKTEVSATRSTAPSVGLSSISITIPPEPLAL--------DNIHLEK------PQYK 2716
TT S +++ P G + PLAL +NI L +
Sbjct: 1597 TTPPSVSQLPPEPPGPP--GFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRV 1654
Query: 2717 EDGKLQLVGDVIDLRTVPK-VEVKTTDKCIDLSASTMDVKRQ-ITANEVYGKQISAVQPS 2774
E G V+DLRT K + TD+ +DL++ ++ ++ + + + G+Q +AVQP
Sbjct: 1655 EPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPL 1714
Query: 2775 IINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAMT---------TPLQ 2825
+INL+ LAT T +T +S + +V + + +P+
Sbjct: 1715 VINLNAQEH----TFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVC 1770
Query: 2826 LTTSKHAE-----PPYR----------------IPSDQVFPIAREEAPINLSLGTPAHAV 2864
L K E PYR +P +QV P+AR + I +GT A ++
Sbjct: 1771 LAQVKQVEQAVQTAPYRSGPRGRPREAKFARYNLP-NQVAPLARRDVLIT-QMGT-AQSI 1827
Query: 2865 TLAITKPVTVPPVGV-TNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKI 2923
L KP VP G + T + + G K H VV M E T+ +T +
Sbjct: 1828 GL---KPGPVPEPGAEPHRATPAELRSHALPG------ARKPHTVVVQMGEGTAGTVTTL 1878
Query: 2924 IEDEK--PVDLTAGR---RAVCCDVVYKLPFGRSCTAQ-QPATTLPEDR----------- 2966
+ +E +DLT R + CCD+VYKLPFG SCT PA ++PE
Sbjct: 1879 LPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSS 1938
Query: 2967 ---FGYRDDH------YQ---------YDRSGPYGYRGIGGMKPSMSDTNLAEAGHFFYK 3008
+G RD Y+ ++ PY G + SMSDTNLAEAG ++
Sbjct: 1939 SPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHA 1998
Query: 3009 SK-NAFDYSEGTDTAVDLTS 3027
+ G D+A+DL+S
Sbjct: 1999 QRIGQLFQGPGRDSAMDLSS 2018
Score = 79.7 bits (195), Expect = 7e-14
Identities = 142/656 (21%), Positives = 213/656 (32%), Gaps = 100/656 (15%)
Query: 1 MGNEASLEGEG----LPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI 56
MGNE SLEG LP G A G GAG P + PAG L +
Sbjct: 1 MGNEVSLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPP--SAPAG-GGQLPAAGAARSTAV 57
Query: 57 AAVMSRAQGLPKGSVP-----------PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRP 105
V G G P P + + ++ ++ P +S R P
Sbjct: 58 PPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGP 117
Query: 106 AQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSA 165
A R T S + GRSPS + S + + + L + S
Sbjct: 118 AGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSD 177
Query: 166 VSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGP 225
++S + S+ + T+ V + G +++ Q+
Sbjct: 178 LTS-----------TPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRAL 226
Query: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQ 285
G D P+S S QQ P + P + P P + ++ P +P ++Q
Sbjct: 227 GMD---MTTAPRSKSQQQLHSPALSPAHS--PAKQPLGKPDQERSRGP---GGPQPGSRQ 278
Query: 286 ADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ-----PSGLTK 340
A+ R SV + + P + + +P P +P + +P + PA+ P+GL
Sbjct: 279 AETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGA 338
Query: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS-----------SEQPGPK 389
Q G + A L +P A G PS S++ GPK
Sbjct: 339 TEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPK 398
Query: 390 ALAQPPGVGKTPAQQP------GPAKPP---TQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
L PG G P + GP P + GT P + Q+ +KA KT
Sbjct: 399 PLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTM 458
Query: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPT-------------KPPSQL-------------- 473
++ + + G S P L
Sbjct: 459 PKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTK 518
Query: 474 ---------PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524
P P PP Q P P + G++ P Q+ P P PAK SP
Sbjct: 519 RLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTS-PLKQKGPQGLGQPSGPLPAKASPLST 577
Query: 525 GSTKPPSQQPGSAKP-SAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP 579
++ PS+ AKP A +PS S Q+ V P PP +P+ P
Sbjct: 578 KASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATP 633
Score = 70.5 bits (171), Expect = 4e-11
Identities = 147/676 (21%), Positives = 235/676 (34%), Gaps = 117/676 (17%)
Query: 1 MGNEASLEGEGL---PE----GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEER 53
+ E LE E L PE G ++ S S T++ + E S S +R
Sbjct: 956 LDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQR 1015
Query: 54 RQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKS 113
+ A +A+ G + P +S +E + ++ R + R
Sbjct: 1016 LEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTR 1075
Query: 114 RTTDTFRSEQKLPGRS--PSTISLKESKSRTD-------LKEEHKSSMM-----PGFLSE 159
R + R++++ PS +S E S T+ ++E H+SS P SE
Sbjct: 1076 RDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSE 1135
Query: 160 VNALSAVSSVVNK-------------FNPFDLISDS-------------EASQEETTKKQ 193
AL S + K ++P + S S E + EE +K
Sbjct: 1136 AEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKA 1195
Query: 194 KVVQKEQGKPEGIIKP---PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQ 250
+++Q++QG+ G P P Q P+ + + QD T + +
Sbjct: 1196 ELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFE-------YQDTTDREYGQAAQPAAEGT 1248
Query: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT 310
P G + + QT + + +++ +SR D+ E K K + +
Sbjct: 1249 PASLGAAVY--EEILQTSQSIVRMRQASSR------DLAFAEDKKKE-----KQFLNAES 1295
Query: 311 PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLA--------QQPGTVKPPVQ-----PPG 357
P +Q G GP P P+ L P++ G V P V+
Sbjct: 1296 AYMDPMKQNG------GPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKE 1349
Query: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPG-PKALAQPPGVGKTPAQQPGPAKPP-TQQV 415
T P PA P + P S+ PG P A P P PA P +++
Sbjct: 1350 TQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERS 1409
Query: 416 GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGK--TSAQQTGPTKPPSQL 473
+P A G G + Q G A +A K +++ G T PS+
Sbjct: 1410 PSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRA 1469
Query: 474 PG---PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP--------PQQPGPAKPSPQ 522
+ PP P++ P PG P + ST+ P P+ PG PSP
Sbjct: 1470 YSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPM 1529
Query: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKP--------SAQQSTKPVSQTGSGKPLQPPTVSP 574
T+ P +P + + Q+ S P A T+ V + S PL SP
Sbjct: 1530 VAQGTQTP-HRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPL----CSP 1584
Query: 575 SAKQPPSQGLPKTICP 590
+ QP + G +T P
Sbjct: 1585 TETQPTTHGYSQTTPP 1600
Score = 60.1 bits (144), Expect = 6e-08
Identities = 148/693 (21%), Positives = 239/693 (34%), Gaps = 116/693 (16%)
Query: 93 PKQSGRPPDPGR--PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKS 150
P Q+ PP+ GR P P +K T + + P +S + + T+ +E +
Sbjct: 290 PAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPA--GLGATEQTQEGLT 347
Query: 151 SMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPP 210
+ G + + L+ S++++ E T+ Q K G P+ +
Sbjct: 348 GKLFGLGASL--LTQASTLMS------------VQPEADTQGQPAPSK--GTPKIVFNDA 391
Query: 211 LQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK---PIQGPTQTPQT 267
++ PKP+ GPG P + E PG+G P G T +P+
Sbjct: 392 SKEAGPKPLGSGPGPGPAP-----------GAKTEPGARMGPGSGPGALPKTGGTTSPKH 440
Query: 268 DHAK-LPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
A+ + A++P+T + + L SK P T Q P
Sbjct: 441 GRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNP 500
Query: 327 GPAKPPAQP----SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS 382
P + TK L + P+ PP + +PP A S
Sbjct: 501 TPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPV--------GAPHRASGTSP 552
Query: 383 SEQPGPKALAQPPGVGKTPAQQPGPAK-PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
+Q GP+ L QP G P PAK P +P P P + P +A P+KTP
Sbjct: 553 LKQKGPQGLGQPSG--------PLPAKASPLSTKASPLPSKASPQAK-PLRASEPSKTPS 603
Query: 442 Q-QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500
Q ++P + + P PP P PA P + P A P
Sbjct: 604 SVQEKKTRVPTK---------AEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPE 654
Query: 501 SQQPGSTKPPPQQP--GPAKPSPQ--------QPGSTKPPSQQPGSAKPSAQQ------- 543
+ + G + +P A SPQ G + S+ G + +Q
Sbjct: 655 APKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVT 714
Query: 544 -PSPAKPS----AQQSTKPVSQ------TGSGKPLQPPTVSPSAKQPPSQGL-PKTICPL 591
P P PS S +P+ Q + KPL T ++P S + P+
Sbjct: 715 GPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSD 774
Query: 592 CNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651
++L + A + E Q T S F V++ + G L+
Sbjct: 775 EELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVED----------SSEGGLS 824
Query: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711
P+P PQP + A +T + + Q + S ++D + D + + L K T
Sbjct: 825 PLP--PQPPARAAELTDEDFMRR---QILEMSAEEDNLEEDDTATSGR-----GLAKHGT 874
Query: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744
G P + + E +L K P + E+
Sbjct: 875 QKGGPRPRPEPSQEPAALPKRRLPHNATTGYEE 907
Score = 60.1 bits (144), Expect = 6e-08
Identities = 248/1193 (20%), Positives = 383/1193 (32%), Gaps = 269/1193 (22%)
Query: 129 SPSTISLKESKSRTDLKEEHKSSMMPGFLSEV------NALSAVSSVVNKFNPFDLISDS 182
+P + E K L+ +++ + P LS++ + + S V+ +P L+ S
Sbjct: 2751 TPGPLGRFEKKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTS 2810
Query: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL------------ 230
AS E K QK + QQ P+P+ Q DP
Sbjct: 2811 FASSERLNKAHVSPQKHFTADSAL----RQQTLPRPMKTLQRSLSDPKPLSPTAEESAKE 2866
Query: 231 ------QQDGTPKSISSQQPE----KIK----SQPP--------GTGKP----------- 257
Q G +S+ P K+K S PP G P
Sbjct: 2867 RFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRG 2926
Query: 258 IQGPTQTPQTDHAKLP--------LQRDASRPQTKQADIVRGES-VKPSLP------SPS 302
+ GPT P T + L ++ ++++ + KQA++ E + L +
Sbjct: 2927 LTGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQR 2986
Query: 303 KPPIQQPTPGK--PPAQQPGHEKSQPGPAK-PPAQPSGLTKPLAQQPGTVKPPVQPPGTT 359
K + + G+ PP + G + ++ + G T P Q V P T
Sbjct: 2987 KESLAKDRGGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTTPAGQF-------VDFPATA 3039
Query: 360 KPPAQPLGPA-------KPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP- 411
PA P GP +PPA Q + Q G A P G P+ P PA PP
Sbjct: 3040 AAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG--PSTYPAPAFPPG 3097
Query: 412 ---TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK 468
+ G P A +P + P PT P P A P +TS
Sbjct: 3098 ASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKV 3157
Query: 469 PPSQ--LPGPAKPPPQQP------GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520
P + + P P P GPA + G P + G Q P P PS
Sbjct: 3158 PTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKV-PEVPRAGDRGSVSQSPAPTYPS 3216
Query: 521 PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580
S + P + K S ST P SQ +PL P + K+P
Sbjct: 3217 DSHYTSLE--QNVPRNYVMIDDISELTKDST--STAPDSQRL--EPLGPGSSGRPGKEPG 3270
Query: 581 SQG-LPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLN 639
G L P C E++ ++ ++P
Sbjct: 3271 EPGVLDGPTLPCCYARG-----EEESEEDS-------------YDP-------------- 3298
Query: 640 CQMKRALGGDLAPVPSSPQPKLK----TAPVTTTSAVSKSSPQPQQTS-PKKDAAPKQDL 694
R GG L + S+ +P + + V K P P P K AP
Sbjct: 3299 ----RGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAIS 3354
Query: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
SK + +K ++Q SP +AK E+D S P P S+ S K D+
Sbjct: 3355 SKRSKHRKQG--MEQKISKFSPIEEAKDV-ESDLASYPPPAVSSSLVSRGRK--FQDEIT 3409
Query: 755 KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTG---- 810
K K + +++ + ++ + P + S F G
Sbjct: 3410 YGLK--KNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDFSGWGKGYE 3467
Query: 811 ---EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867
E V KA P+P+S S S P S+ ++ PV P
Sbjct: 3468 REREAVERLQ-KAGPKPSSLSMAHSRVRPPMRSQASEEESPV---------------SPL 3511
Query: 868 AKPMPKGSPTPPG----PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK------ 917
+P P G P PPG P+ + ++P Q+ K ++ + G I D
Sbjct: 3512 GRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDS 3571
Query: 918 -----SQPTT-----PQETVTGKLFGFGASIFSQASNLISTAGQP------------GPH 955
Q T P++ + + G S +S A PH
Sbjct: 3572 EAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPH 3631
Query: 956 SQSGPGAPMKQAPAPSQPPTSQG--PPKSTGQAP----------------------PAPA 991
+ GPG + A A G + TG+ P P+ A
Sbjct: 3632 DEGGPG---RHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSA 3688
Query: 992 KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKK-------PPPIKDSKSLTAEPQKAV 1044
++P K + P++ + + + KK P SK AEPQ
Sbjct: 3689 PAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSK---AEPQAQP 3745
Query: 1045 LPTKLEKSPKPESTCPLCKTELNIG--SKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQ 1102
+ +P P+ + ++ G S+ P + + Q L P LT+ +
Sbjct: 3746 QLQGRQAAPGPQQSQSPSSRQIPSGAASRQP-------QTQQQQQGLGLQPPQQALTQAR 3798
Query: 1103 EWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVK 1155
L Q+Q G PA S P P P P+ ++ + A PP+ +
Sbjct: 3799 ----LQQQSQPTTRGS-------APAASQPAGKPQPGPSTATGPQPAGPPRAE 3840
Score = 59.3 bits (142), Expect = 1e-07
Identities = 77/279 (27%), Positives = 110/279 (39%), Gaps = 42/279 (15%)
Query: 312 GKPPAQQPGHEKSQPGP-------AKPPAQPSGL-TKPLAQQPGTVKPPVQPPGTTKPPA 363
G+ ++PG ++P A+P +QPS P QPG ++ +
Sbjct: 3655 GRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYP--------SSAEYS 3706
Query: 364 QPLGPAKPPAQQTGSEKPSSE-QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422
QP + + S+K S + GP AL P Q A P QQ + P +
Sbjct: 3707 QPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQ--SQSPSS 3764
Query: 423 QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
+Q + ++ P +T QQ G G P QQA QQ+ PT S P ++P +
Sbjct: 3765 RQIPSGAASRQP---QTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSA-PAASQPAGK 3820
Query: 483 -QPGPAKPPPQQP-------------GSAKPPSQQPGSTKPPPQQPGPA--KPSPQQPGS 526
QPGP+ QP G+AK P Q P PGPA K + G+
Sbjct: 3821 PQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGT 3880
Query: 527 TKPPSQQPGSAKPSAQQ---PSPAKPSAQQSTKPVSQTG 562
P+ QPG+ S P A A + T+ VS G
Sbjct: 3881 PGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAFG 3919
Score = 56.2 bits (134), Expect = 8e-07
Identities = 96/442 (21%), Positives = 152/442 (34%), Gaps = 70/442 (15%)
Query: 322 EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381
+K+ P P+ S + P+ Q + PV P G +P PL P Q S
Sbjct: 3477 QKAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHS 3536
Query: 382 SSE-----QPGPKALAQPPGVGK---------TPAQQPGPAKPPTQQVGTPKPLAQQP-- 425
+ + GP+A A G + ++ + T P+
Sbjct: 3537 MPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFR 3596
Query: 426 -----GLQSPAKAPGPTKTPV----QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476
+ S ++ GP + + P G P + GPG+ ++ + + G
Sbjct: 3597 HHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSG- 3655
Query: 477 AKPPPQQPG--PAKPPPQQPGSAKP-PSQQPGSTKPPPQQPGPAKPSP---QQPGSTKPP 530
+ ++PG AKP + G + P QP S P++ P PS QP
Sbjct: 3656 -RHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSA 3714
Query: 531 SQQPGSAKPSAQQ----PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
+K ++Q P+ + A+ +P Q P + SPS++Q PS +
Sbjct: 3715 YHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASR 3774
Query: 587 TICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRAL 646
L L P++A LT+ + L Q +
Sbjct: 3775 QPQTQQQQQGLGLQPPQQA-----------------------LTQAR----LQQQSQPTT 3807
Query: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE----PKK 702
G AP S P K + P T T P+ +QT+ K A +AP+ P
Sbjct: 3808 RGS-APAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGP 3866
Query: 703 PPPLVKQPTL-HGSPSAKAKQP 723
P VK G+P A A QP
Sbjct: 3867 GPAGVKAGARPGGTPGAPAGQP 3888
Score = 55.8 bits (133), Expect = 1e-06
Identities = 107/482 (22%), Positives = 165/482 (34%), Gaps = 60/482 (12%)
Query: 24 GGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPK-GSVPPAAAESPSMH 82
GG+S + +PS + D S + R+ AV + PK S+ A +
Sbjct: 3438 GGSSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPM 3497
Query: 83 RKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRT 142
R Q + P GRP G P PG T F S +P
Sbjct: 3498 RSQASEEESPVSPLGRPRPAGGPLPPG---GDTCPQFCSSHSMPDVQEHV---------K 3545
Query: 143 DLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA---SQEETT--KKQKVVQ 197
D H G++ + + ++SDSEA QEET K + +
Sbjct: 3546 DGPRAHAYKREEGYILD--------------DSHCVVSDSEAYHLGQEETDWFDKPRDAR 3591
Query: 198 KEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQ------DGTPKSISSQQPEKIKSQP 251
++ + G Q P +P ++ +G P +S + +
Sbjct: 3592 SDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHG 3651
Query: 252 PGTGKPI-QGPTQTPQTDHAKLPLQRDA---SRPQTKQADIVRGESVKPSLPSPSKPPIQ 307
+G+ + P + HA+ + +A S+P + A +G+ PS S+P
Sbjct: 3652 RHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRA 3711
Query: 308 QPTPGKPPAQQPGHEKSQPGPA------KPPAQPSGLTKPLAQQPGTVKPPVQ---PPGT 358
+ G ++ GPA +P AQP + A P + P P G
Sbjct: 3712 SSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGA 3771
Query: 359 T----KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ-QPGPAKPPTQ 413
+ Q G P QQ ++ +Q P P + + QPGP+
Sbjct: 3772 ASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGP 3831
Query: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473
Q P Q G + AKAP + P QP PG PA K A+ G P+
Sbjct: 3832 QPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGV----KAGARPGGTPGAPAGQ 3887
Query: 474 PG 475
PG
Sbjct: 3888 PG 3889
Score = 50.1 bits (118), Expect = 6e-05
Identities = 59/247 (23%), Positives = 91/247 (36%), Gaps = 33/247 (13%)
Query: 713 HGSPSAKAKQPPEADSLSKPAPPK--EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770
H + + P + S PA PK +P PS + + QP S S
Sbjct: 3670 HARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYS--------QPSRASSAYHHASDS 3721
Query: 771 S-ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS--QSFPPTGEKVSPFDSKAIPRPASD 827
+ + + +QS+AE + P L+ A P QS P+ ++ + P+
Sbjct: 3722 KKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQ 3781
Query: 828 SKIISHPGPS---SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884
+ + P ++++ Q+Q P + P +Q P+P P P P GP P
Sbjct: 3782 QQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPG--PSTATGPQPAGP-PR 3838
Query: 885 AGQT------VPTPQQSPKPQEQSR--------RFSLNLGSITDAPKSQPTTPQETVTGK 930
A QT PQQ PQ Q + G AP QP E+V K
Sbjct: 3839 AEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSK 3898
Query: 931 LFGFGAS 937
+ GA+
Sbjct: 3899 ILPGGAA 3905
Score = 47.4 bits (111), Expect = 4e-04
Identities = 154/705 (21%), Positives = 241/705 (34%), Gaps = 133/705 (18%)
Query: 227 RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPI-QGPTQTPQTDHAKLPLQRDASRPQTKQ 285
+DPL+ +P S SS E G P QGP T A P
Sbjct: 1351 QDPLKLHSSPASPSSASKE--------IGMPFSQGPGTPATTAVAPCP------------ 1390
Query: 286 ADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP----PAQPSGLT-- 339
A + RG + P+ P+ S+ + P+P A GH + P PSGL
Sbjct: 1391 AGLPRGY-MTPASPAGSE---RSPSPSST-AHSYGHSPTTANYGSQTEDLPQAPSGLAAA 1445
Query: 340 ------KPLAQQPGTVKPPVQPP------GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG 387
KPL+ G P QP ++ PP P P++ P G + G
Sbjct: 1446 GRAAREKPLSASDGEGGTP-QPSRAYSYFASSSPPLSPSSPSESPTFSPG-------KMG 1497
Query: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447
P+A A+ +TP+ P P + TP P+ Q G Q+P + P V Q
Sbjct: 1498 PRATAEFST--QTPSPAPASDMPRSPGAPTPSPMVAQ-GTQTPHRPSTPRL--VWQESSQ 1552
Query: 448 KIPAQQAGPGKTSAQQT---------GPTKPPSQL------------PGPAKPPPQQPGP 486
+ P ++ QT P P++ P ++ PP+ PGP
Sbjct: 1553 EAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGP 1612
Query: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK--PPSQQPGSAKPSAQQP 544
P A P G P + + S PG+++ P + PG+A +
Sbjct: 1613 PGFPRVPSAGADGPLALYGWGALPAENISLCRIS-SVPGTSRVEPGPRTPGTAVVDLR-- 1669
Query: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEK 604
+ KP+ P+ T G L V +P + L+ E
Sbjct: 1670 TAVKPT------PIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEH 1723
Query: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLK 662
T T T+ S + + + K+ + + L D SP ++K
Sbjct: 1724 TFLATATTVSITMAS------SVFMAQQKQPVVYGDPYQSRL--DFGQGGGSPVCLAQVK 1775
Query: 663 TAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQ 722
+A +S P+ + P++ + +L P + PL ++ L Q
Sbjct: 1776 QVEQAVQTAPYRSGPRGR---PREAKFARYNL-----PNQVAPLARRDVL-------ITQ 1820
Query: 723 PPEADSLS-KPAPPKEPSVPSEQDKAPVADDKPKQ-PKMVKPTTDLVSSSSATTKPDIPS 780
A S+ KP P EP +E +A A+ + P KP T +V T +
Sbjct: 1821 MGTAQSIGLKPGPVPEPG--AEPHRATPAELRSHALPGARKPHTVVVQMGEGT------A 1872
Query: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS-PFDSKAI----PRPASDSKIISHPG 835
V + E+ L +P PF S P P+ K ++
Sbjct: 1873 GTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAA 1932
Query: 836 PSSESKG--QKQVDPVQKKEEPKKAQTKMSPKP--DAKPMPKGSP 876
P +S DP + +AQ + P P + +P P+G P
Sbjct: 1933 PPGQSSSPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLP 1977
Score = 45.1 bits (105), Expect = 0.002
Identities = 55/199 (27%), Positives = 75/199 (37%), Gaps = 15/199 (7%)
Query: 801 KPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS---HPGPSS-ESKGQKQVDP-VQKKEEP 855
K +P + E P + + ASDSK S H GP++ +SK + Q P +Q ++
Sbjct: 3694 KGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAA 3753
Query: 856 KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS---PKPQEQSRRFSLNLGSI 912
Q SP P S P + G + PQQ+ + Q+QS+ +
Sbjct: 3754 PGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPA 3813
Query: 913 TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ 972
P +P T TG G Q + TA P Q G AP Q PAP
Sbjct: 3814 ASQPAGKPQPGPSTATGPQPA-GPPRAEQTNGSKGTAKAP----QQGR-APQAQ-PAPGP 3866
Query: 973 PPTSQGPPKSTGQAPPAPA 991
P G P APA
Sbjct: 3867 GPAGVKAGARPGGTPGAPA 3885
Score = 40.0 bits (92), Expect = 0.060
Identities = 56/219 (25%), Positives = 75/219 (34%), Gaps = 53/219 (24%)
Query: 2399 LDISAQPPPPPPPPPPPPPPPPPP-------------------PPPPLPPPTSP---KPT 2436
L+ S P P PPP PP P P PLP SP K +
Sbjct: 521 LEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKAS 580
Query: 2437 ILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS--IP 2494
LP K A P+ + P + E + + P+ + PP P P++ +
Sbjct: 581 PLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPK----PPPETTPTPATPKVK 636
Query: 2495 SGLVFTHRPEPSKP-----PIAP----------KPVIPQLPTTTQKPTDIHPKPTGLSLT 2539
SG+ R EP+ P P AP KP + Q +D G+S +
Sbjct: 637 SGV---RRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSS 693
Query: 2540 SSMTLNLV-------TSADYKLPSPTSPLSPHSNKSSPR 2571
S +V SA P P SP H SS R
Sbjct: 694 QSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMR 732
Score = 39.7 bits (91), Expect = 0.078
Identities = 59/242 (24%), Positives = 83/242 (34%), Gaps = 36/242 (14%)
Query: 217 KPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQR 276
KP+ G G GTP+ + S P P + PT +P + +
Sbjct: 1452 KPLSASDGEG-------GTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEF 1504
Query: 277 DASRPQTKQA-DIVRGESVKPSLPSPSKPPIQQ--PTPGKPPAQQ-PGHEKSQPGP---- 328
P A D+ R P P+PS P + Q TP +P + E SQ P
Sbjct: 1505 STQTPSPAPASDMPRS----PGAPTPS-PMVAQGTQTPHRPSTPRLVWQESSQEAPFMVI 1559
Query: 329 --------AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
S T PL P +P T PP+ P +PP
Sbjct: 1560 TLASDASSQTRMVHASASTSPLCS-PTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRV 1618
Query: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
PS+ GP AL G G PA+ + + P +PG ++P A +T
Sbjct: 1619 PSAGADGPLALY---GWGALPAENISLCRISS----VPGTSRVEPGPRTPGTAVVDLRTA 1671
Query: 441 VQ 442
V+
Sbjct: 1672 VK 1673
Score = 39.7 bits (91), Expect = 0.078
Identities = 41/161 (25%), Positives = 52/161 (32%), Gaps = 32/161 (19%)
Query: 335 PSGLTKPLAQQPGTVKPPVQPPGTTKP---------------------PAQPLGPA---- 369
P T P+ QP +V P+ G +P P PLGP
Sbjct: 2201 PIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYR 2260
Query: 370 --KPPAQQTGSEKPSSEQP---GPKALAQPPGVG--KTPAQQPGPAKPPTQQVGTPKPLA 422
P S P +E P G A A+ PG G P G A+ TP +
Sbjct: 2261 YPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIK 2320
Query: 423 QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463
+ G +PA G PG G + G K A Q
Sbjct: 2321 EAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQ 2361
Score = 39.7 bits (91), Expect = 0.078
Identities = 58/241 (24%), Positives = 86/241 (35%), Gaps = 55/241 (22%)
Query: 4833 DHGKSHSSQSSQQSPKPSVIKSRSHGI-----FPDPSKDMQV--------PTIEKSHSSP 4879
D G+ + SQ S P++ K G + PS+ ++HS P
Sbjct: 3673 DLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGP 3732
Query: 4880 GSSKSSSE--------GHLRSHGPSRSQSKTS----------VTQTHLEDAGAAIAAAEA 4921
+ +S +E G + GP +SQS +S QT + G + +
Sbjct: 3733 AALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQ 3792
Query: 4922 AVQQLRIQPTKPPNHR---PAESSV--------STGSSGSSFGSGYSVDSEGSSSTAGET 4970
A+ Q R+Q P R PA S ST + G + + GS TA
Sbjct: 3793 ALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTA--- 3849
Query: 4971 NLFPIPRIGKMGQNGQEPVKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEI 5030
K Q G+ P QP G G A +A + G A + DGE + +I
Sbjct: 3850 ---------KAPQQGRAPQAQPAPGPGPAGVKAGAR-PGGTPGAPAGQPGADGESVFSKI 3899
Query: 5031 L 5031
L
Sbjct: 3900 L 3900
Score = 37.0 bits (84), Expect = 0.51
Identities = 61/265 (23%), Positives = 91/265 (34%), Gaps = 70/265 (26%)
Query: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
P PLPPPTS +P + + + SP+ P + G P + P
Sbjct: 528 PTPLPPPTSQQPPVGAPHRASGTSPLKQKGP--------------QGLGQP------SGP 567
Query: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT 2543
P P S + P PSK KP+ P+ T P+ + K T
Sbjct: 568 LPAKASPLSTKAS------PLPSKASPQAKPLRASEPSKT--PSSVQEKKT--------- 610
Query: 2544 LNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITS 2603
+ T A+ P P P ++P+ + +EP TP + +A
Sbjct: 611 -RVPTKAE---PMPKPPPETTPTPATPKVKSGVRR--------AEPATPVVKAVPEA--- 655
Query: 2604 WPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAP 2663
P G ++DLV +P A P S T Y S + SS Q+
Sbjct: 656 -PKGGEAEDLVG-KPYSQ-----DASRSPQSLSDTGYSSDGI-----------SSSQSEI 697
Query: 2664 TSVTQFLTTEVSKTEVSATRSTAPS 2688
T V Q ++ V+ +PS
Sbjct: 698 TGVVQQEVEQLDSAGVTGPHPPSPS 722
Score = 35.0 bits (79), Expect = 1.9
Identities = 30/128 (23%), Positives = 50/128 (39%), Gaps = 16/128 (12%)
Query: 3559 TYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPK 3618
T+ G +G + A+ TQ+P A+ P+ PTP S + A T P P
Sbjct: 1490 TFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTP------SPMVAQGT--QTPHRPS 1541
Query: 3619 SPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRS 3678
+P++++ S +P + A D S +++H + P SP +
Sbjct: 1542 TPRLVWQESSQEAPFMVITLA--------SDASSQTRMVHASASTSPLCSPTETQPTTHG 1593
Query: 3679 MSDPKPLS 3686
S P S
Sbjct: 1594 YSQTTPPS 1601
Score = 34.7 bits (78), Expect = 2.5
Identities = 62/266 (23%), Positives = 93/266 (34%), Gaps = 42/266 (15%)
Query: 321 HEKSQPGPAKPPAQPS---GLTKP---LAQQPGTVKPPVQPPGTTKPP-AQPLGPAKPPA 373
H GP QP GL+ P + +PG + P P G P GPA
Sbjct: 2115 HGSGGGGPDLVQYQPQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQG 2174
Query: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP--TQQVGTPKPLAQQPGLQSPA 431
PS+ + G+ + P A P TQ +P+ + G+ P
Sbjct: 2175 TAVRQLLPSTA-----TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPY 2228
Query: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ-------P 484
+ G T P+ + A + G T + PS+ P + PP + P
Sbjct: 2229 ASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRY---PAPSRFPIASSVPPAEGPVYLGKP 2285
Query: 485 GPAKPP-------PQQP-GSAKP---PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS-- 531
AK P P+ P G+A+ P+ P + K P PA + Q+P + P
Sbjct: 2286 AAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGG 2345
Query: 532 ----QQPGSAKPSAQQPSPAKPSAQQ 553
+PG K A Q + +Q
Sbjct: 2346 SGALSRPGFEKEEASQEERQRKQQEQ 2371
Score = 34.3 bits (77), Expect = 3.3
Identities = 38/147 (25%), Positives = 51/147 (34%), Gaps = 24/147 (16%)
Query: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL----PPPTS 2432
PS SP+ S PR ++ + S Q P P P P P P P P + P
Sbjct: 1485 PSESPTFSPGKMGPR-----ATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHR 1539
Query: 2433 PKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP------PPV 2486
P L ++ + +P T DA + S P+ T P
Sbjct: 1540 PSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTS-PLCSPTETQPTTHGYSQTT 1598
Query: 2487 PPKPSSIPSGLVFTHRPEPSKPPIAPK 2513
PP S +P PEP PP P+
Sbjct: 1599 PPSVSQLP--------PEPPGPPGFPR 1617
Score = 34.3 bits (77), Expect = 3.3
Identities = 17/30 (56%), Positives = 21/30 (70%), Gaps = 2/30 (6%)
Query: 4524 PGHSGEIGAYIAKILPGGSAEQTGKLMEGM 4553
PG GE + +KILPGG+AEQ GKL E +
Sbjct: 3888 PGADGE--SVFSKILPGGAAEQAGKLTEAV 3915
Score = 33.1 bits (74), Expect = 7.3
Identities = 74/330 (22%), Positives = 121/330 (36%), Gaps = 39/330 (11%)
Query: 2276 SVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSL 2335
+ VP + + + DL + E + K KK+ + ++A EL + K SL
Sbjct: 2931 TTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESL 2990
Query: 2336 SETVF--DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKP--- 2390
++ D+PP + ++ LS + G PA Q P+ ++ PA P
Sbjct: 2991 AKDRGGRDYPPLRGLG-EHRDYLSDSELNQLRLQGCTTPAGQFVD-FPATAAAPATPSGP 3048
Query: 2391 ----RPFFRSSSLDISA-------------QPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
+P F+ + SA Q P P P P P PP P P
Sbjct: 3049 TAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPN 3108
Query: 2434 KPTILPKKKLTVASPV-TTATPLF----DAVTTLE---TTAVLRSNGLPVTRICTTAPPP 2485
+ P +P+ TT + LF D+ L+ T++ T A P
Sbjct: 3109 QQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPV 3168
Query: 2486 VPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL---PTTTQKPTDIHPKPTG-LSLTSS 2541
VP SS PS ++ S P +P+ + +Q P +P + SL +
Sbjct: 3169 VP--MSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQN 3226
Query: 2542 MTLNLVTSADY-KLPSPTSPLSPHSNKSSP 2570
+ N V D +L ++ +P S + P
Sbjct: 3227 VPRNYVMIDDISELTKDSTSTAPDSQRLEP 3256
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 221 bits (562), Expect = 2e-56
Identities = 361/1449 (24%), Positives = 515/1449 (35%), Gaps = 259/1449 (17%)
Query: 157 LSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPP 216
+S +AL+ V+S + DS AS ++K + P G+ P ++PP
Sbjct: 754 ISHTSALAPVASSPKECPT----EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809
Query: 217 KPIPKQQGPGRDPLQQDGTP-KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ 275
K+ G D TP ++SS S P QG +P T H+ P
Sbjct: 810 T---KKGSAGPD------TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860
Query: 276 -RDASRPQTKQADIVRGESVKPS-LPSPS--KPPIQQPTPGKP-PAQQPGHEKSQPGPAK 330
+ A P +G ++ P P+PS P + P P P Q P + P K
Sbjct: 861 PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920
Query: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKP--------PAQQTGSEKPS 382
A P+ P + P K PP T PP+ GPA P PA S K
Sbjct: 921 ARATPAPKGIPASPSP---KGAPTPPAAT-PPSPKGGPATPSPKWAPTPPAATPPSPKGG 976
Query: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP-- 440
P PK PP P+ + GPA P + G P P A P SP +P T P
Sbjct: 977 PATPSPKGAPTPPAA-TPPSPKGGPATPSPK--GAPTPPAVTP--PSPKGSPAATPFPKG 1031
Query: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500
P P+ + P T + PT P + LP P + GPA P + G+ PP
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP------KGGPATPSLK--GAPTPP 1083
Query: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
+ P S K P P P K +P P +T PPS + G A P P P+ +T P +
Sbjct: 1084 AATPPSPKGGPATPSP-KGAPMPPAAT-PPSPKGGLATP----PHKGAPTTPAATPPSPK 1137
Query: 561 TG------SGKPLQPPTVSPSAK----QPPSQGLPKTICPLCNTTELLLHVPEKANFNTC 610
G G P P PS K PP +G P T + + L P T
Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT- 1196
Query: 611 TECQTTVCSLCGF-NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK-------LK 662
T T G P+P G P + P PK K
Sbjct: 1197 TPAATPPSPKGGLATPSPK------------------GAPTTPAATPPSPKGGLATPSPK 1238
Query: 663 TAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL---VKQPTLHGSPSAK 719
AP TT A + SP+ +P AP P PP L + P G+P+
Sbjct: 1239 GAP--TTPAATPPSPKGGPATPPPKGAP------TPPAATPPSLKGGLATPPHKGAPNPA 1290
Query: 720 AKQPPEADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
PP +PPK P+ P+ +P PK PT V+ S P +
Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA-PTPPAVTPPSPKGTPTL 1349
Query: 779 PSSKVQSQ-------AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD---- 827
P++ S+ ++E TPP T S K + P K P AIP P D
Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP----AIPSPKGDPTSP 1405
Query: 828 -----------SKIISHPGPSSESKGQ---KQVDPVQKKEEPKKAQTKMSPKPDAKPMPK 873
+ ++ G ++ SKG V PV K+ P + K P A P K
Sbjct: 1406 AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP---ATPSSK 1462
Query: 874 GSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFG 933
G PT P P P+P++ P P++ + S T AP PT P
Sbjct: 1463 GDPTLPAVTP------PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP---------- 1506
Query: 934 FGASIFSQASNLISTAGQPGPHSQSGPGAP-----MKQAPAPSQPPTSQGPPKSTGQAPP 988
A I S + +T P S+ P AP K+ PA P + PP T P
Sbjct: 1507 --AVIPSSPKEVPAT-----PSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT---VP 1556
Query: 989 APAK--SIPVKKETKAPAAEK--LEPKAEQAPTVKRTETEKK---PPPIKDSKSLTAEPQ 1041
+P K +IP KE A + K P A T K + K+ PP + A
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616
Query: 1042 KAVLPTKLEK---SPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHL 1098
AV P EK +P P+ T P KD P CK
Sbjct: 1617 PAVTPPSPEKGPATPAPKGT-PTSPPVTPSSLKDSPTSPASVTCK--------------- 1660
Query: 1099 TEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVK 1158
+ +A G +K P A +P P T + T PQ K
Sbjct: 1661 --------MGATVPQASKGL--PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSS 1710
Query: 1159 KQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPL--PE 1216
+ + K + + P +++ SK K K ++ K PL PE
Sbjct: 1711 ATSPPICPDPS----AKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPE 1766
Query: 1217 EKKLIP----EEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQK----------H 1262
K P EK+ + + + P L P + P +Q+
Sbjct: 1767 SKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLE 1826
Query: 1263 DLLKSQVQIAEEKLEGRVAPKTVQEG--------KQPQTKMEGLPSGTPQS--------- 1305
K E++L + P+ + G P K G+P TP +
Sbjct: 1827 SPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNK 1886
Query: 1306 ---LPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSD 1362
+ D++ ++EQ T + Q+ E E+ K+ S S++ K+ + +S
Sbjct: 1887 GSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEK-KARKAMSK 1945
Query: 1363 TGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEA 1422
G + + + K+IL + K + SP+S + + E+ + L
Sbjct: 1946 LGL------RQVTGVTRVTIRKSKNILFVITKPDVYK--SPASDTYIVFGEAKI-EDLSQ 1996
Query: 1423 QASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKD 1482
QA A EK K Q VS QE TQ + T++ EEE+ E+ E KD
Sbjct: 1997 QAQLAAAEKF--KVQGEAVS----NIQENTQ--TPTVQEESEEEEVDETGVEVKDIELVM 2048
Query: 1483 SQQDIPSSK 1491
SQ ++ +K
Sbjct: 2049 SQANVSRAK 2057
Score = 147 bits (370), Expect = 3e-34
Identities = 310/1334 (23%), Positives = 419/1334 (31%), Gaps = 231/1334 (17%)
Query: 210 PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
PL Q PK P Q P P S + +K +P GKP T
Sbjct: 561 PLVQAAPKNSPSFQSTSSSP----EIPLSPEATLAKKSLGEPLPIGKPASSMTS------ 610
Query: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
PL ++S K +S P L K + PT P + P A
Sbjct: 611 ---PLGVNSSASVIKTDSYAGPDSAGPLL----KSSLITPTVAAFPLESADPAGVAPTTA 663
Query: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP-GP 388
K + + P + ++ P P K P P A + PS + P
Sbjct: 664 KGTSTYTTTASPFLEGTVSLAPKNHP---VKEGTLTTLPLVPTASENCPVAPSPQNTCAP 720
Query: 389 KA-LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447
A L P + P P P+ PP GTP + G+ S A P + P
Sbjct: 721 LATLVLAPEI---PKSVPSPSLPPA---GTPPGTKKVDGI-SHTSALAPVAS-----SPK 768
Query: 448 KIPAQQAGPGKTSAQQ---TGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504
+ P + +G T++ + T PS L P K PP + GSA P + P
Sbjct: 769 ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ------TKRPPTKKGSAGPDT--P 820
Query: 505 GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-S 563
P P A P+ S + P + S PSP + P+S G +
Sbjct: 821 IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH-SPTPPSPKGAPTPSAVTPLSPKGVT 879
Query: 564 GKPLQPPTVS----PSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619
P + PT S P K+ P+ PK L T+ P+KA T
Sbjct: 880 LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS----PKKAR-------ATPAPK 928
Query: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVT-------TTSAV 672
+P+P G P + P PK P T T A
Sbjct: 929 GIPASPSPK------------------GAPTPPAATPPSPK--GGPATPSPKWAPTPPAA 968
Query: 673 SKSSPQPQQTSPKKDAAPKQDLSKAPEPK-----------KPPPLVKQPTLHGSPSAK-- 719
+ SP+ +P AP + P PK PP V P+ GSP+A
Sbjct: 969 TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028
Query: 720 ---AKQPPEADSLSKPAPPKEPSVPSEQDKAPVA-----DDKPKQPKMV-KPTTDLVSSS 770
A PP A S P +P P A P P + PT +
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088
Query: 771 SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK---AIP----- 822
S P PS K T P K A P PT +P K A P
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 823 ------RPASDSKIISHPGPSSESKGQKQVDPVQK----KEEPKKAQTKMSPKPD----- 867
P S ++ P P P K PK A T + P
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 868 -AKPMPKGSPTPPG---PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP 923
A P PKG+PT P P P G P+P+ +P + S G T PK PT P
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-SPKGGPATPPPKGAPTPP 1267
Query: 924 QETVTGKLFGFGASIFSQASN-LISTAGQP--GPHSQSGPGAPMKQAPAPSQPPTSQGPP 980
T G A N + T P GP + GAP A P P S G P
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Query: 981 KSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040
G AP PA + P K T P P ++ PT ++ PP A P
Sbjct: 1328 PPKG-APTPPAVTPPSPKGT--PTLPATTPSSKGGPTTPSSKEGPTPP--------AATP 1376
Query: 1041 QKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTE 1100
P SPK P K G P + K TP E
Sbjct: 1377 SHKGGPAMTPPSPKRGPAIPSPK-----GDPTSPAVIPLSPKKAPA--------TPVTRE 1423
Query: 1101 IQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQ 1160
T A++ K PA S PK P ++ AV P
Sbjct: 1424 GAATPSKGDLTPPAVTPV---SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPA 1480
Query: 1161 EQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDK------ASALQEKKP- 1213
++V T + + +P ++ + K+ + + A+ L +K P
Sbjct: 1481 PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA 1540
Query: 1214 -LPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIA 1272
L ++ LIP + S +K P + PTP++ P +K
Sbjct: 1541 TLAPKEALIPPAMTVPSPKKTPAI----PTPKEAPATPSSK------------------- 1577
Query: 1273 EEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPD-- 1330
E V P T +G PS P+ L T+ + KE P PP P
Sbjct: 1578 EASSPPAVTPST----------YKGAPS--PKELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625
Query: 1331 --QVEPGKEKTEKEDDKSDTSSSQQPKSPQGL-----SDTGYSSDGISSSLG-------- 1375
P + T + +S P SP + + +S G+ + G
Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685
Query: 1376 --EIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSE 1433
P P KG + S S P P AK S A A L +K
Sbjct: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS 1745
Query: 1434 KKTQPHEVSPEQPK 1447
KT + + PK
Sbjct: 1746 SKTAKGKDASHSPK 1759
Score = 88.6 bits (218), Expect = 1e-16
Identities = 204/939 (21%), Positives = 296/939 (31%), Gaps = 180/939 (19%)
Query: 275 QRDASRPQTKQADIVRGESVKPSL----PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAK 330
+++ +PQ + A + ++ + P P+ PP P P + P P P+
Sbjct: 13 EQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPST 72
Query: 331 PPAQP---------SGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--LGPAKPPAQQTGSE 379
+ P SG PL P + P P PP P L A P T
Sbjct: 73 IASTPLEVPFPQSSSGTALPLGTAP---EAPTFLPNLIGPPISPAALALASPMIAPTLKG 129
Query: 380 KPSSEQP-----------------GPKALAQPPGVGK-------TPAQQPGPAKPPTQQV 415
PSS P P L PP V T + P++P T
Sbjct: 130 TPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLN 189
Query: 416 GTPKPLAQQP-GLQSP----AKAPGPTKTPVQQPGPGKIPAQQAGPGKT----------- 459
P + P G SP + P TP+ G Q P T
Sbjct: 190 KVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDT 249
Query: 460 --SAQQTGPTKPPS-QLPGPAKPP----------------PQQPGPAKPP--PQQPGSAK 498
S+ P P S L GP PP + GP PP P GS
Sbjct: 250 TISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHL 309
Query: 499 PPSQQPG-STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS------A 551
P Q + Q GP+ S + G++ PS + P PS A
Sbjct: 310 APLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPA 369
Query: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611
+ PV K P T+S P T L TT L+L A ++
Sbjct: 370 TVAAFPVVAPSVDK--GPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPL 427
Query: 612 ECQTTVCSLCGFNP----NP------HLTEVKEWLCLNCQMKRALGGDLAP------VPS 655
Q V S+ G P NP T + C++ M ++ P V +
Sbjct: 428 VAQMPVSSV-GTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMA 486
Query: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK----PPPLVKQPT 711
PK + V TT + S P P K P L K P K P L P
Sbjct: 487 PVAPKEPSTQVATTLRIPVSPPLPDPEDLKN--LPSSVLVKFPTQKDLQTVPASLEGAPF 544
Query: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQD--------KAPVADDKPKQPKMV-KP 762
K+ P L + AP PS S +A +A +P + KP
Sbjct: 545 SPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKP 604
Query: 763 TTDL-----VSSSSATTK------PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811
+ + V+SS++ K PD ++S T +SA P+ P T +
Sbjct: 605 ASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAK 664
Query: 812 KVSPFDSKAIP------------RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ 859
S + + A P P + + + P + S+ Q P
Sbjct: 665 GTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATL 724
Query: 860 TKMSPKPDAKPMPKGSP--TPPGPRPTAG--------QTVPTPQQSPKPQEQSRRFSLNL 909
P + P P P TPPG + G +P++ P + + +
Sbjct: 725 VLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSK 784
Query: 910 GSIT---DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ----SGPGA 962
G++T D+P G S+ Q + G GP + S P +
Sbjct: 785 GTLTYLADSPSP---------------LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVS 829
Query: 963 PMKQAPAPSQPPTSQG----PPKSTGQAPPAP-AKSIPVKKETKAPAAEKLEPKAEQAPT 1017
P++ + P + QG P + PP+P P +P L PK P+
Sbjct: 830 PVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPS 889
Query: 1018 VKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056
V K+ P K A + P K +P P+
Sbjct: 890 VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK 928
Score = 80.1 bits (196), Expect = 5e-14
Identities = 141/598 (23%), Positives = 197/598 (32%), Gaps = 79/598 (13%)
Query: 2161 SLILTYSEP-SESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITK 2219
+L+L P S + S+PP+ TP T V + T + +P+ + P + T+
Sbjct: 723 TLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVA---------SSPKECPTE 773
Query: 2220 FEDSEEISSSTYFPGSIIDYPEEISVSLD----RTAPPDGRASADHIVISLSDMASSIIE 2275
+ +SS + D P + VS+ R G A D + +LS S +
Sbjct: 774 DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA 833
Query: 2276 SVVPK-----------------PEGPVADTVSTDLLISEKDP--VKKAKKETGNGIIL-- 2314
S +P+ P P T ++ P V KET ++
Sbjct: 834 SFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL 893
Query: 2315 ----EVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTS------G 2364
E K+ T SS + P + A P + T + G
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG 953
Query: 2365 ETFGQEKPASQLPSGS-PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP 2423
K A P+ + PS PA P P + + +A PP P P P P P P
Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSP--KGAPTPPAATPPSPKGGPATPSPKGAPTP 1011
Query: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTT---------ATPLFDAVTTLETTAVLRSNGLP 2474
P PP P P K P T ATPL T + G P
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071
Query: 2475 VTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQ--LPTTTQK-----PT 2527
T AP P P S P G T P+ + P A P P+ L T K P
Sbjct: 1072 ATPSLKGAPTPPAATPPS-PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
Query: 2528 DIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPS 2587
P P G L + T+ PSP L+ K +P T T PS
Sbjct: 1131 ATPPSPKG-GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP--------TTPAATPPS 1181
Query: 2588 EPG---TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGA 2644
G TP+ A + P SP L + P + P P T GA
Sbjct: 1182 PKGGLATPSPKGAPTTPAATP-PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240
Query: 2645 LQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP 2702
T +ATP +P A P + + +T P G + ++ PP P
Sbjct: 1241 PTTPAATP-PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297
Score = 76.6 bits (187), Expect = 6e-13
Identities = 235/1064 (22%), Positives = 344/1064 (32%), Gaps = 196/1064 (18%)
Query: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
P Q P++ + + PGPT P P P + P ++A Q P
Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL-------SAANQASPFPS 69
Query: 470 PSQL---PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526
PS + P P G A P P + P+ P PP A SP +
Sbjct: 70 PSTIASTPLEVPFPQSSSGTALPLGTAP---EAPTFLPNLIGPPISPAALALASPMIAPT 126
Query: 527 TK--PPSQQP----GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK------PLQPPTVSP 574
K P S P A S Q+ S P+ S V+ SG P+ P
Sbjct: 127 LKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKT 186
Query: 575 SAKQPPSQGLPK---TICPLCNTTELLLHVPEKANFNTCTECQTTVCSL-CGFNPNPHLT 630
+ + PS+ +P T P C + + H C T + S+ G P T
Sbjct: 187 NLNKVPSEVVPNPKGTPSPPCIVSTVPYH------------CVTPMASIQSGVASLPQTT 234
Query: 631 EVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ-PQQTSPKKDAA 689
+ Q+K + P +P PV+ +A+S S+ P TS +K A
Sbjct: 235 PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAG 294
Query: 690 PK------------------------QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725
P Q L + P VK T+ S+ P
Sbjct: 295 PNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVK--TISVDHSSTGASYPS 352
Query: 726 ADSLSKPAPPKEPSVPSEQDKAP-VADDKPKQPKMV-------------------KPTTD 765
S+ P P + VP+ P VA K P + PTT
Sbjct: 353 QRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTS 412
Query: 766 LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD----SAKPSQSFPPTGEKVSPFDSKAI 821
L+ SS P + TTP + T+ +A P+ +F P S I
Sbjct: 413 LILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPI 472
Query: 822 P--RPASDSKIISHPGPSSESKGQKQV-----------DPVQKKEEPKKAQTKMSPKPDA 868
P S + ++ P E Q DP K P K + D
Sbjct: 473 SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532
Query: 869 KPMPKGSPTPPGPRPTAGQT-------VPTPQQSPK--PQEQSRRFSLNLGSITDAPKSQ 919
+ +P P AG T +P Q +PK P QS T +
Sbjct: 533 QTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQS----------TSSSPEI 582
Query: 920 PTTPQETVTGKLFGFGASIFSQASNLISTAGQPG------PHSQSGP--GAPMKQAPAPS 971
P +P+ T+ K G I AS++ S G S +GP P+ ++ +
Sbjct: 583 PLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLIT 642
Query: 972 QPPTSQGPPKSTGQAPPAP--AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
P + P +S A AP AK T +P LE AP K P
Sbjct: 643 -PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF---LEGTVSLAP---------KNHP 689
Query: 1030 IKDSKSLTAEPQKAVLPTKLEKSPKPESTC-PLCKTEL------NIGSKDPPNFNTCTEC 1082
+K+ +LT P +P P++TC PL L ++ S P T
Sbjct: 690 VKEG-TLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGT 748
Query: 1083 KNQVCNLCGFNPTPHLTEIQEWLCLNCQTQ----RAISGQLGDIRKMPPAPSGPKASPMP 1138
K + G + T L + C T+ A + G + + +P SP+
Sbjct: 749 K----KVDGISHTSALAPVAS-SPKECPTEDSGASATASSKGTLTYLADSP-----SPLG 798
Query: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEES 1198
V S S +T PP KK T + + P+ + +
Sbjct: 799 V---SVSPQTKRPP----TKKGSAGPDTPIGNL----------SSPVSPVEASFLPENSL 841
Query: 1199 KLEKDKASALQEKKPLPEEKKLIPEEEKIR--SEEKKPLLEEKKPTPEDKKL-LPEAKTS 1255
+ K S P P K P + S + L ++ PTP L P+ +
Sbjct: 842 SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901
Query: 1256 APEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK 1315
P ++ L S + +K APK + P+ P+ TP S PK T
Sbjct: 902 TPAPKQAPAL-SMTSSSPKKARATPAPKGIPASPSPKGAPTP-PAATPPS-PK-GGPATP 957
Query: 1316 TIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQG 1359
+ K P PP P P + T + P SP+G
Sbjct: 958 SPKWAPTPPAATPP---SPKGGPATPSPKGAPTPPAATPPSPKG 998
Score = 73.6 bits (179), Expect = 5e-12
Identities = 122/507 (24%), Positives = 174/507 (34%), Gaps = 84/507 (16%)
Query: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPS 131
PP+ E P+ KQ SS P K P G P P + S + +
Sbjct: 1472 PPSPKEPPAP--KQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529
Query: 132 TISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTK 191
T +L K+ L K +++P ++ + + K P S +S T
Sbjct: 1530 TATLLSKKTPATLAP--KEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587
Query: 192 KQKVVQKEQGKPEGIIKPPLQQQP-PKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQ 250
K P+ ++ PP P PK P TP +++ PEK +
Sbjct: 1588 S---TYKGAPSPKELLIPPAVTSPSPKEAP--------------TPPAVTPPSPEKGPAT 1630
Query: 251 PPGTGKPIQGPTQTPQ------TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKP 304
P G P P TP T A + + A+ PQ +G K P+ K
Sbjct: 1631 PAPKGTPTSPPV-TPSSLKDSPTSPASVTCKMGATVPQAS-----KGLPAKKG-PTALKE 1683
Query: 305 PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ 364
+ P P P + P P + S T P + K + P +T PA
Sbjct: 1684 VLVAPAPESTPI------ITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA- 1736
Query: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP------ 418
PL P + + +T K +S P GP PP + TP
Sbjct: 1737 PLLPVQKDSSKTAKGKDASHSP------------------KGPLAPPESKASTPLTAAAF 1778
Query: 419 KPLAQQPGLQSPAKAPGPTKTPVQQP-GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
+ + +P S + AP P PV P P +P P K QQ P+ P L P+
Sbjct: 1779 EKVLPKPESASVSAAPSP---PVSLPLAPSPVPTL---PPK---QQFLPSSPGLVLESPS 1829
Query: 478 KP--PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP--SQQ 533
KP P + P +P S P Q P P+ G P+P S K P
Sbjct: 1830 KPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTP----SAKQPVTKNN 1885
Query: 534 PGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
GS S S + Q ST+ +Q
Sbjct: 1886 KGSGTESDSDESVPELEEQDSTQATTQ 1912
Score = 73.2 bits (178), Expect = 6e-12
Identities = 129/531 (24%), Positives = 209/531 (39%), Gaps = 100/531 (18%)
Query: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482
P P LPPP SP P P ASP + + + A T LE S+G T +
Sbjct: 41 PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTI--ASTPLEVPFPQSSSG---TALPLGT 95
Query: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSM 2542
P P T P PPI+P + P I P G + +SS
Sbjct: 96 APEAP------------TFLPNLIGPPISPAALALASPM-------IAPTLKG-TPSSSA 135
Query: 2543 TLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITL-----PSEPGTPTDSSA 2597
L LV A + + +S P+ S P S ++ E+ VITL PSEP T +
Sbjct: 136 PLALVALAPHSV-QKSSAFPPNLLTSPP--SVAVAESGSVITLSAPIAPSEPKTNLNKVP 192
Query: 2598 SQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPS 2657
S+ + + P G+PS + + V P+ +++ ++S L + T A +
Sbjct: 193 SEVVPN-PKGTPSPPCIVSTVPYHCVTPMASIQSGVAS---------LPQTTPTTTLAIA 242
Query: 2658 SFQAAPTSVTQFLTTEVSKTEVSATRSTAP--SVGLSSISITI------------PPE-P 2702
S Q T+++ L + + +S +P ++ LS+ S+ + PP+ P
Sbjct: 243 SPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFP 302
Query: 2703 LALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANE 2762
++L + HL G +QL+G +T P T K I + S+
Sbjct: 303 ISLGS-HLAPLHQSSFGSVQLLG-----QTGPSALSDPTVKTISVDHSSTGAS------- 349
Query: 2763 VYGKQISAVQP-----SIINLSVTS-SIVTP-VSLATETVTFVTCTASASYTTGTESLVG 2815
Y Q S + P ++ +V + +V P V T++ +TC+ S S T +
Sbjct: 350 -YPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSL- 407
Query: 2816 AEHAMTTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVP 2875
+ TT L L +S +A Y P P++ S+GT L +T P T+
Sbjct: 408 ---SPTTSLILKSSPNA--TYHYPLVAQMPVS--------SVGT----TPLVVTNPCTIA 450
Query: 2876 PVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTV---VTMDESTSSVMTKI 2923
T + VS ++ G + ++ T V V E ++ V T +
Sbjct: 451 AAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTL 501
Score = 73.2 bits (178), Expect = 6e-12
Identities = 81/315 (25%), Positives = 123/315 (39%), Gaps = 43/315 (13%)
Query: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP---PPLPPPTSP 2433
P G P+ S P P +A PP P P PPP P PP PP P T
Sbjct: 1297 PKGGPATSPPKGAPTP--------PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348
Query: 2434 KPTILPKKKLTVASPVT-------TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV 2486
P P K +P + ATP + + R +P + T+P +
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Query: 2487 PPKPSSIPSGLVFTH-RPEPSKPPIAPKPVIPQLPTTTQKPTDIHPK--PTGLSLTSSMT 2543
P P P+ V PSK + P V P + + P PK P S T
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTP--VSLKKAPATSAPKGGPATPSSKGDPT 1466
Query: 2544 LNLVTSADYKLPSPTSPLSPH--SNKSSPRFSKSLTETYVVITLPSE-PGTPTDSSASQA 2600
L VT PSP P +P + SSP+ + + TLP+ P +P + A+ +
Sbjct: 1467 LPAVTP-----PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS 1521
Query: 2601 ITSWPLGSPSKDLVS------VEPVFSVVPPVTAVEIP-----ISSEQTFYISGALQTFS 2649
P+ +P+ L+S + P +++PP V P I + + + + + S
Sbjct: 1522 SRRDPI-APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS 1580
Query: 2650 ATPVTAPSSFQAAPT 2664
+ P PS+++ AP+
Sbjct: 1581 SPPAVTPSTYKGAPS 1595
Score = 71.2 bits (173), Expect = 2e-11
Identities = 97/395 (24%), Positives = 143/395 (36%), Gaps = 51/395 (12%)
Query: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
D P +V + +K+ +T+ G K LP+ +P P P+ SSS
Sbjct: 1432 DLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPK 1491
Query: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPP-----PTSPKPTILPKK-------------- 2441
+ P P P P P P P P P +P T+L KK
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 2442 KLTVASPVTT----------ATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491
+TV SP T ATP ++ G P + P P P
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611
Query: 2492 SIPSGLVFTHRPEPSKPPIAPKPV-IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSA 2550
P+ T P P K P P P P P T P+ + PT + + V A
Sbjct: 1612 EAPTPPAVT-PPSPEKGPATPAPKGTPTSPPVT--PSSLKDSPTSPASVTCKMGATVPQA 1668
Query: 2551 DYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPL-GSP 2609
LP+ P + +P E+ +IT P+ G T S++ TS P+ P
Sbjct: 1669 SKGLPAKKGPTALKEVLVAP-----APESTPIITAPTRKGPQTKKSSA---TSPPICPDP 1720
Query: 2610 SKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSAT-PVTAPSSFQAAPTSVTQ 2668
S S P+ +V P A +P+ + + G + S P+ P S + P +
Sbjct: 1721 SAKNGSKGPLSTVAP---APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
Query: 2669 FLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPL 2703
F +V SA+ S APS +S+ + P P+
Sbjct: 1778 F--EKVLPKPESASVSAAPS---PPVSLPLAPSPV 1807
Score = 62.0 bits (149), Expect = 1e-08
Identities = 93/361 (25%), Positives = 130/361 (36%), Gaps = 48/361 (13%)
Query: 2373 ASQLPSGSPSV-SSLPAKPR-----PFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP 2426
A+ P G+P+ ++ P P+ P + + +A PP P P PPP P PP
Sbjct: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269
Query: 2427 LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV 2486
PP P K + VT +P T+ G P T P
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS-------PPKGAP------TPPAAT 1316
Query: 2487 PPKPSSIPSGLVFTHRP-EPSKPPIAPKPVIPQLPTTTQK----PTDIHPK--PTGLSLT 2539
PP P P P P+ P +PK P LP TT PT K PT + T
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGT-PTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375
Query: 2540 SSMTLN-LVTSADYK----LPSPT-SPLSPHSNKSSPRFSKSLTETYVVITLPSE----P 2589
S +T K +PSP P SP SP+ + + T PS+ P
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435
Query: 2590 GTPTDSSASQA-ITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTF 2648
T S +A TS P G P+ +P V P + E P + S
Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495
Query: 2649 SATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRST----------APSVGLSSISITI 2698
+ P+ AP+ P+S + T S+ + A +T AP L ++T+
Sbjct: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV 1555
Query: 2699 P 2699
P
Sbjct: 1556 P 1556
Score = 60.1 bits (144), Expect = 6e-08
Identities = 96/375 (25%), Positives = 138/375 (36%), Gaps = 68/375 (18%)
Query: 2326 LEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSS 2385
L +++T ++L+ PP+ + P K T + T P+S+ S P+V+
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT-----PSSKEASSPPAVTP 1587
Query: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTV 2445
K P + + PP P P P PP + PP+ K P K T
Sbjct: 1588 STYKGAPSPKELLI----------PPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637
Query: 2446 ASPVTTATPLFDAVTT-------LETTAVLRSNGLPVTRICTTAPPP-VPPKPSSIPSGL 2497
SP T + L D+ T+ + T S GLP + T V P P S P
Sbjct: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
Query: 2498 VFTHRPEPSK------PPIAPKPVI---PQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548
T + +K PPI P P + P +T P + P S T+
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTA-------- 1749
Query: 2549 SADYKLPSPTSPLSPHSNKSS-----PRFSKSL--TETYVVITLPSEP--------GTPT 2593
SP PL+P +K+S F K L E+ V PS P PT
Sbjct: 1750 KGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPT 1809
Query: 2594 DSSASQAITSWP---LGSPSKDLVSV--EPVFSVVPPVTAVEIPISSE---QTFYISGAL 2645
Q + S P L SPSK L + + ++PP PIS Q+ ++
Sbjct: 1810 LPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPE-----PISGGVPFQSVLVNMPT 1864
Query: 2646 QTFSATPVTAPSSFQ 2660
+ PV PS+ Q
Sbjct: 1865 PKSAGIPVPTPSAKQ 1879
Score = 49.7 bits (117), Expect = 8e-05
Identities = 87/369 (23%), Positives = 125/369 (33%), Gaps = 51/369 (13%)
Query: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP-- 2426
+E + LP + + P P P + L P P P P PP PP
Sbjct: 691 KEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKK 750
Query: 2427 ----------LPPPTSPK--PTILPKKKLTVASPVTTATPLFDAVTTLETTA-------- 2466
P +SPK PT T AS T T L D+ + L +
Sbjct: 751 VDGISHTSALAPVASSPKECPTEDSGASAT-ASSKGTLTYLADSPSPLGVSVSPQTKRPP 809
Query: 2467 VLRSNGLPVTRICTTAPPPVPPKPSSIP-SGLVF---------THRPEPSKPPIAPKP-- 2514
+ + P T I + P P + S +P + L F TH P P P AP P
Sbjct: 810 TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869
Query: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSK 2574
V P P P P P+ ++L P+P + SSP+ ++
Sbjct: 870 VTPLSPKGVTLPPKETPTPSVVNLP-------FPKEGPATPAPKQAPALSMTSSSPKKAR 922
Query: 2575 SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPIS 2634
+ + PS G PT +A+ P G P+ + P ++ PP P
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPS---PKGGPA----TPSPKWAPTPPAATPPSPKG 975
Query: 2635 SEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAP-SVGLSS 2693
T GA +ATP +P A P+ V+ + + P G S+
Sbjct: 976 GPATPSPKGAPTPPAATP-PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034
Query: 2694 ISITIPPEP 2702
PP P
Sbjct: 1035 PPAATPPSP 1043
Score = 43.1 bits (100), Expect = 0.007
Identities = 134/564 (23%), Positives = 193/564 (34%), Gaps = 110/564 (19%)
Query: 2182 PSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPE 2241
P+L +S SV +S S IT I +EP + K P ++ P+
Sbjct: 155 PNLLTSPPSVAVAESGSVITLSAPIAP--SEPKTNLNKV------------PSEVVPNPK 200
Query: 2242 EISVSLDRTAPPDGRASAD-HIVISLSDMASSIIESVVPKPEGPVA-------DTVSTDL 2293
+PP ++ H V ++ + S + P +A DT + +
Sbjct: 201 ------GTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSV 254
Query: 2294 LISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMK 2353
LIS ++P + K G L + K++ T D P S L
Sbjct: 255 LISPQNPGSLSLK--GPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPL 312
Query: 2354 EQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP 2413
Q S F S + GQ P++ P+V ++ S S PP P
Sbjct: 313 HQSS---FGSVQLLGQTGPSAL---SDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEV 366
Query: 2414 PPPPP---PPPPPPPPLPPPTSPKPTILPKKKLTVA-----SPVTT--------ATPLFD 2457
P P P P T T P L VA SP T+ AT +
Sbjct: 367 VPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYP 426
Query: 2458 AVTTLETTAVLRSNGLPVTRICTTAPPP---------VPPKPSSIPSGLVFTHRPEPSKP 2508
V + ++V + L VT CT A P V P SS P + EP+ P
Sbjct: 427 LVAQMPVSSV-GTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNI-----EPTSP 480
Query: 2509 ------PIAPKPVIPQLPTTTQKPTDIH-PKPTGL-SLTSSMTLNLVTSADYKLPSPTSP 2560
P+APK Q+ TT + P P P L +L SS+ + T D + T P
Sbjct: 481 AALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQ----TVP 536
Query: 2561 LSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVF 2620
S SP LT LP P +S + Q+ +S P
Sbjct: 537 ASLEGAPFSPA-QAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSP--------------- 580
Query: 2621 SVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTE-V 2679
EIP+S E T P+ P+S +P V + V KT+
Sbjct: 581 ---------EIPLSPEATL---AKKSLGEPLPIGKPASSMTSPLGVNS--SASVIKTDSY 626
Query: 2680 SATRSTAPSVGLSSISITIPPEPL 2703
+ S P + S I+ T+ PL
Sbjct: 627 AGPDSAGPLLKSSLITPTVAAFPL 650
Score = 40.8 bits (94), Expect = 0.035
Identities = 62/257 (24%), Positives = 96/257 (37%), Gaps = 35/257 (13%)
Query: 3485 PTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVD 3544
P+ R A GD + A PLS + A E T G + P++
Sbjct: 1387 PSPKRGPAIPSPKGDPTSPA--VIPLSPKKAPATPVTRE-GAATPSKGDLTPPAV---TP 1440
Query: 3545 AKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHL 3604
++ SAP KGG ++ D L A +PP K+ P P ++ SS
Sbjct: 1441 VSLKKAPATSAP----KGGPATPSSKGDPT------LPAVTPPSPKEPPAPKQVATSSSP 1490
Query: 3605 RADSTVQLAPSPPKSPKVLYS-----PISPLSPGKALESAFVPYEKPLPDDISPQKVLHP 3659
+ P P V+ S P +P S + K P ++P++ L P
Sbjct: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550
Query: 3660 DMAKVPPASPKTAKMMQRSMSDPK--PLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQ 3717
VP SPK ++ PK P +P++ E+S P Y KG+ S +
Sbjct: 1551 PAMTVP--SPKKTP----AIPTPKEAPATPSSKEASSPPAVTPSTY--KGA----PSPKE 1598
Query: 3718 KKVKRTLPNPPPEEIST 3734
+ + +P P+E T
Sbjct: 1599 LLIPPAVTSPSPKEAPT 1615
Score = 38.1 bits (87), Expect = 0.23
Identities = 52/223 (23%), Positives = 82/223 (36%), Gaps = 30/223 (13%)
Query: 3496 KYGDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISA 3555
K G ++ +A K P K + + + + ++ P+ I P+ + K
Sbjct: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI--ITAPTRKGPQTKKSSATSPPIC 1717
Query: 3556 PEKTYKGGSLG----------CQTEADSDTQSPQYLSATSP-----PKDKKRPTPLEIGY 3600
P+ + K GS G + DS + ++ SP P + K TPL
Sbjct: 1718 PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
Query: 3601 SSHLRA---DSTVQLAPSPPKSPKVLYSPIS---------PLSPGKALESAFVPYEKPLP 3648
+ ++V APSPP S + SP+ P SPG LES P
Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADE 1837
Query: 3649 DDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691
D++ P P VP S +S P P +P+A +
Sbjct: 1838 DELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVP-TPSAKQ 1879
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 176 bits (446), Expect = 5e-43
Identities = 227/923 (24%), Positives = 336/923 (36%), Gaps = 131/923 (14%)
Query: 94 KQSGRPP---DPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKS 150
K + +PP + G G K T DT ++ SP + K R L +
Sbjct: 77 KPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 136
Query: 151 SMMPGFL--SEVNALSAVSSVVNKFNPFD----------LISDSEASQEETTKKQKVVQK 198
S E + ++ NK D S + S ++ KV+ K
Sbjct: 137 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196
Query: 199 EQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ-------PEKIKSQP 251
K E K P P +P P ++ TP +I S P KS P
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256
Query: 252 PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ---TKQADIVRGESVK--PSLPSPSKPPI 306
+P T+ P K P P TK A E P P+P+ P
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316
Query: 307 QQPTPGKPPA----QQPGHEKSQPGPAKP----PAQPSGLTKPLAQQPGTVKPPVQPPGT 358
PT K P ++P +P P P P P ++P P P T
Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376
Query: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA----QQPGPAKPPTQQ 414
TK P+ P P +P T S ++++P P P K P+ ++P P P
Sbjct: 377 TKEPS-PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 435
Query: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474
TPK +P +P K P PT TP + P T+ ++ PT P P
Sbjct: 436 PTTPK----KPAPTTP-KEPAPT-TPKE-------------PAPTTTKKPAPTTPKE--P 474
Query: 475 GPAKPPPQQP-GPAKPPPQQPGSAKPPS-QQPGSTKP------PPQQPGPAKPSPQQPGS 526
P P P P K P P P + ++P T P P++P P +P++P
Sbjct: 475 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT--TPEEPAP 532
Query: 527 TKPPSQQPGSAKPSA----QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
T P + P + K A ++P+P P T P P P +P+ + P+
Sbjct: 533 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA----PTTPKGTAPTTLKEPAP 588
Query: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTE-CQTTVCSLCGFNP-NPHLTEVKEWLCLNC 640
PK P EL ++ TC + TT P P T KE
Sbjct: 589 TTPKKPAP----KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 644
Query: 641 Q--MKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA--APKQDLSK 696
+ L P P PK + AP TT S +S +P T+PK+ A PK+
Sbjct: 645 KGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 703
Query: 697 APE------PKKPPPL---VKQPTLHGSPSAKAKQPPEA--DSLSKPAP------PKEPS 739
P+ P+ PPP V PT P+ K P E+ + ++P P PKEP
Sbjct: 704 TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 763
Query: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDS 799
VP+ K P A +P+M D + T P+ ++ + E TT T+S
Sbjct: 764 VPT--TKTPAA----TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 817
Query: 800 ---AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
A +Q T + +PF + K+ ++ K + + K EE
Sbjct: 818 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKV------TTTKKTITTTEIMNKPEETA 871
Query: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTA---GQTVP---TPQQSPKPQEQSRRF-SLNL 909
K + + + P P+ PT +PT+ +T+P P+ +P P++ + LN
Sbjct: 872 KPKDRATNSKATTPKPQ-KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNP 930
Query: 910 GS-ITDAPKSQPTTPQETVTGKL 931
S I +A T P +T KL
Sbjct: 931 TSRIAEAMLQTTTRPNQTPNSKL 953
Score = 166 bits (421), Expect = 4e-40
Identities = 236/1014 (23%), Positives = 357/1014 (35%), Gaps = 168/1014 (16%)
Query: 348 TVKPPVQPPGTTKPPAQPL--GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405
T K P P L G K T + + + PK P P
Sbjct: 74 TKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP-------INP 126
Query: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG----KTSA 461
P+ PP T K + ++ + T T Q GK A KTSA
Sbjct: 127 RPSLPPNSD--TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA 184
Query: 462 QQTGPT---------KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512
+ PT K + GPA P++P P P ++P S P P + K P
Sbjct: 185 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTTIKSAPT 242
Query: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTV 572
P P+ + T P P + K A +P +P+ + +P T P P
Sbjct: 243 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEP 301
Query: 573 SPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEV 632
+P+ + P+ PK P P++ T E P P E
Sbjct: 302 APTTPKKPAPTTPKEPAPT---------TPKEPTPTTPKE------------PAPTTKE- 339
Query: 633 KEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ 692
P P++P+ TAP K +P T+PK+ P
Sbjct: 340 -------------------PAPTTPKEPAPTAPKKPAPTTPK---EPAPTTPKE---PAP 374
Query: 693 DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVA-- 750
+K P P P PT S K+P + S P PKEPS + ++ AP
Sbjct: 375 TTTKEPSPTTPKE--PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 432
Query: 751 DDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKT---TPPLKTDSAKPSQSFP 807
+ P PK PTT + + +P ++K + K T P +T P + P
Sbjct: 433 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 492
Query: 808 PTGEKVSPFDSKAIPRPASDSKII----SHPGPSSESKGQKQVDPVQKKEEPK------- 856
T EK++P + P P + ++ P P++ + PK
Sbjct: 493 TTPEKLAPTTPEK-PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551
Query: 857 KAQTKMSPKPDAKPMPKGSP--TPPGPRPTA-GQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
K +PK A PK + TP G PT + PT + P P+E + + S T
Sbjct: 552 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611
Query: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973
K PTTP+ T + + + P + P P K AP P
Sbjct: 612 -CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 670
Query: 974 PTSQGPPKSTGQ--APPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIK 1031
T++GP +T AP P ++ P + AP K + APT T + PPP
Sbjct: 671 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-----KPAPT-----TPETPPP-- 718
Query: 1032 DSKSLTAEPQKAVLPTKLEKSP---KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCN 1088
+ S + P PT + KSP PE + L K+P T T +
Sbjct: 719 -TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK--- 774
Query: 1089 LCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKT 1148
P +T + + T+R D+R P + A M T ++++KT
Sbjct: 775 -------PEMTTTAK----DKTTER-------DLRTTPETTTA--APKMTKETATTTEKT 814
Query: 1149 AVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ----------KQEES 1198
+ K+ Q T + K+ TL + P VTT + K EE+
Sbjct: 815 T---ESKITATTTQVTSTTTQDTTPFKI-TTLKTTTLAPKVTTTKKTITTTEIMNKPEET 870
Query: 1199 KLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK-KPLLEEKKPTPEDKKLLPEAKTSAP 1257
KD+A+ + P P++ P++ + K P + + K TP +K+ ++ P
Sbjct: 871 AKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKM----TSTMP 926
Query: 1258 EEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGK----QPQTKMEGLPSG-TPQSL 1306
E L +IAE L+ P K P+++ G G TP L
Sbjct: 927 E------LNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHML 974
Score = 118 bits (295), Expect = 2e-25
Identities = 191/869 (21%), Positives = 301/869 (34%), Gaps = 150/869 (17%)
Query: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711
P P++P+ T P T KS+P T+PK + AP S PK+P P +
Sbjct: 216 PTPTTPKEPASTTPKEPTPTTIKSAP----TTPK-EPAPTTTKSAPTTPKEPAPTTTKEP 270
Query: 712 LHGSPSAKA----KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767
+P A K+P + S P PKEP+ + + AP +P +PT
Sbjct: 271 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP 330
Query: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
+ TTK P++ E T P K P + P T ++ +P +K P P +
Sbjct: 331 KEPAPTTKEPAPTTP----KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE-PSPTTP 385
Query: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP-----TPPGPR 882
+ P P++ P KE P TK +P +P P + TP P
Sbjct: 386 KE----PAPTTTKSA-----PTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 435
Query: 883 PTAGQT-VPTPQQSPKPQ--EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939
PT + PT + P P ++ + + T + PTTP+ET
Sbjct: 436 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA------------ 483
Query: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKE 999
P + P P K AP + P P + P P + P +
Sbjct: 484 ------------PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 531
Query: 1000 TKAPAAEKLEPKAEQAPTVKRTE---TEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056
P A E APT + T K+P P ++ P K PT L K P P
Sbjct: 532 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTL-KEPAPT 589
Query: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116
+ EL + P TC + P P +
Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDK------------PAPTTPK---------------- 621
Query: 1117 GQLGDIRKMP--PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILE 1174
G P PAP+ PK P PT + K P +K + T +K +
Sbjct: 622 ---GTAPTTPKEPAPTTPKE---PAPT---TPKGTAPTTLK------EPAPTTPKKPAPK 666
Query: 1175 KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP 1234
++ T + K P T+D KP P P+E + ++
Sbjct: 667 ELAPTTT--KGPTSTTSD-------------------KPAPTT----PKETAPTTPKEPA 701
Query: 1235 LLEEKKPTPEDKKLLP----EAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEG-K 1289
KKP P + P E T ++ + KS + E L PK ++ K
Sbjct: 702 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE-LSAEPTPKALENSPK 760
Query: 1290 QPQTKMEGLPSGT-PQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDT 1348
+P P+ T P+ DKTT+ TA P + TEK + T
Sbjct: 761 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT 820
Query: 1349 SSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSD 1408
+++ Q S T + + ++ + + T +K I + ++ + P D
Sbjct: 821 ATTTQVTSTTTQDTTPFKITTLKTT--TLAPKVTTTKKTI---TTTEIMNKPEETAKPKD 875
Query: 1409 LAKLESTVLSILEAQASTLADEK----SEKKTQPHEVSPE-QPKDQEKTQSLSETLEITI 1463
A ++ + + Q T A +K + KT P P+ P ++ T ++ E +
Sbjct: 876 RA--TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR 933
Query: 1464 SEEEIKESQEERKDTFKKDSQQDIPSSKD 1492
E + ++ T + P S+D
Sbjct: 934 IAEAMLQTTTRPNQTPNSKLVEVNPKSED 962
Score = 99.8 bits (247), Expect = 6e-20
Identities = 183/812 (22%), Positives = 276/812 (33%), Gaps = 137/812 (16%)
Query: 691 KQDLSKAPEPKKPPPLVKQ--------------PTLHGSPSAKAKQPPEADSLSKPAPPK 736
K K P PK PP+V + P + K P+ + +KP P+
Sbjct: 71 KNRTKKKPTPK--PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT-AKPINPR 127
Query: 737 EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLK 796
PS+P P +D + V T + + + TT + + + +EKTT
Sbjct: 128 -PSLP------PNSDTSKETSLTVNKETTVETKETTTT-----NKQTSTDGKEKTT---- 171
Query: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES--KGQKQVDPVQKKEE 854
SAK +QS EK S D A SK+++ P P +E+ KG P +
Sbjct: 172 --SAKETQSI----EKTSAKDL------APTSKVLAKPTPKAETTTKGPALTTPKEPTPT 219
Query: 855 PKKAQTKMSPKPDAKPMPKGSPTPPG-PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
K +PK K +PT P P PT ++ PT + P P T
Sbjct: 220 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP--------------T 265
Query: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973
+ PTTP+E A ++ +T P + P P K AP +
Sbjct: 266 TTKEPAPTTPKEP---------APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316
Query: 974 PTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS 1033
P P + T P PA P KE AP K E APT KKP P
Sbjct: 317 PAPTTPKEPTPTTPKEPA---PTTKEP-APTTPK-----EPAPTAP-----KKPAPTTPK 362
Query: 1034 KSLTAEPQKAVLPTKLEKSPK-PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGF 1092
+ P++ T E SP P+ P +K+P T +
Sbjct: 363 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK------ 416
Query: 1093 NPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPP 1152
P+P T+ + + PAP+ PK P P + + T P
Sbjct: 417 EPSPTTTK---------EPAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKKP 466
Query: 1153 QVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKK 1212
K+ E +K+ T + EK+ P TT +K + E+ + +E
Sbjct: 467 APTTPKEPAPTTPKETAPTTPKKLTPT-TPEKLAP--TTPEKPAPTTPEELAPTTPEEPT 523
Query: 1213 PL-PEEKKLIPEEEKIRSEEKKPL-LEEKKPTPEDKK-----LLPEAKTSAPEEQKHDLL 1265
P PEE + + K+P K+P P K E + P+ L
Sbjct: 524 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 583
Query: 1266 KSQVQIAEEKLEGR-VAPKTVQE---------------GKQPQTKMEGLPSGTPQSLPKE 1309
K +K + +AP T +E G P T E P+ + P
Sbjct: 584 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 643
Query: 1310 DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDG 1369
T T ++P P KP E T + S TS P +P+ + T
Sbjct: 644 PKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 701
Query: 1370 ISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLAD 1429
++ P+ T S ++ P+ + K L A+ + A
Sbjct: 702 PTTPKKPAPTTPETPPP------TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 755
Query: 1430 EKSEKKT-QPHEVSPEQPKDQEKTQSLSETLE 1460
E S K+ P +P K + T + +T E
Sbjct: 756 ENSPKEPGVPTTKTPAATKPEMTTTAKDKTTE 787
Score = 91.7 bits (226), Expect = 2e-17
Identities = 179/818 (21%), Positives = 269/818 (32%), Gaps = 96/818 (11%)
Query: 2164 LTYSEPSESATSVPP-SDTPSLTS-SVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFE 2221
+T ++P S+PP SDT TS +V+ T ++ TT +T E + +
Sbjct: 118 ITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ 177
Query: 2222 DSEEISSSTYFPGS-IIDYPEEISVSLDR----TAP--PDGRASADHIVISLSDMASSII 2274
E+ S+ P S ++ P + + + T P P + + + + I
Sbjct: 178 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 237
Query: 2275 ESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSS 2334
+S P+ P A T + + K+P KE A KE TK
Sbjct: 238 KSAPTTPKEP-APTTTKSAPTTPKEPAPTTTKEP----------APTTPKEPAPTTTKEP 286
Query: 2335 LSETVFDHP--PSSVIALPMKEQLSTTYFTSGETFGQEK----PASQLPSGSPSVSSLPA 2388
T P P K+ TT T +E P P+ + P
Sbjct: 287 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 346
Query: 2389 KPRPFFRSSSLDISAQPPPPPPPPPPPPP----PPPPPPPPPLPPPTSPKPTIL--PKKK 2442
+P P + + P P P P P P P P P P T PT P
Sbjct: 347 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406
Query: 2443 LTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHR 2502
T ++P T P TT E TT P P P +
Sbjct: 407 TTKSAPTTPKEP--SPTTTKEPAP-------------TTPKEPAPTTPK----------K 441
Query: 2503 PEPSKPPIAPKPVIPQ--LPTTTQKPTDIHPK---PTGLSLTSSMTLNLVTSADYKLPSP 2557
P P+ P P P P+ PTTT+KP PK PT T+ T +T + +P
Sbjct: 442 PAPTTPK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP 500
Query: 2558 TSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVE 2617
T+P P ++P T T P EP T +A+ P + K+
Sbjct: 501 TTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 558
Query: 2618 P--VFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVS 2675
P P TA P + T L+ + T P+ + APT+ + +T
Sbjct: 559 PKEPAPTTPKETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 613
Query: 2676 KTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPK 2735
K + + TAP+ + T P EP P+ L+ + PK
Sbjct: 614 KPAPTTPKGTAPTTP-KEPAPTTPKEPAP------TTPKGTAPTTLKEPAPTTPKKPAPK 666
Query: 2736 VEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETV 2795
TT K +++T D T E P+ ++ TP +E
Sbjct: 667 ELAPTTTK--GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 724
Query: 2796 TFVTCTASASYTTGTESLVGAEHAMTTPLQLTTS--KHAEPPYRIPS-----------DQ 2842
T T + + A TP L S + P + P+ D+
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 784
Query: 2843 VFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVTNGWTDSTVSQGITDGEVVDLST 2902
P + T T+ T + T ST +Q T ++ L T
Sbjct: 785 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 844
Query: 2903 TKSHRTVVTMDE--STSSVMTKIIEDEKPVDLTAGRRA 2938
T V T + +T+ +M K E KP D +A
Sbjct: 845 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 882
Score = 70.1 bits (170), Expect = 5e-11
Identities = 113/523 (21%), Positives = 162/523 (30%), Gaps = 88/523 (16%)
Query: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPST 132
P E P+ +EL + P + + P+ P P K+ +T + + P+
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAPNTPKEPAPTTPKEPAP 556
Query: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192
+ KE TT K
Sbjct: 557 TTPKE------------------------------------------------PAPTTPK 568
Query: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252
+ +G +K P P KP PK+ P ++ T + P K P
Sbjct: 569 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP---TTTKEPTSTTCDKPAPTTPKGTAP 625
Query: 253 GTGK---PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
T K P P T P P T + + E + P+ +P
Sbjct: 626 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTSDKP 684
Query: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA 369
P P P K +P P P KP P T P T +P
Sbjct: 685 APTTPKETAPTTPK-EPAPTTP-------KKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 736
Query: 370 KPPAQQTGSEKPSSEQPGPKAL---AQPPGV--GKTPAQQPGPAKPPTQQVGTPKPLAQQ 424
K P + T S +P PKAL + PGV KTPA + T + L
Sbjct: 737 KSPDEST---PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTT 793
Query: 425 PGLQSPA-KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483
P + A K T T ++ KI A T+ Q T P K + P
Sbjct: 794 PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT 853
Query: 484 PGPA------KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
P++ K + +T P PQ+P A P++P STK P P
Sbjct: 854 TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA---PKKPTSTKKPKTMPRVR 910
Query: 538 KPSAQQPSPAK-PSAQQSTKPVSQTGSG--KPLQPPTVSPSAK 577
KP P+P K S P S+ + P +P++K
Sbjct: 911 KPKT-TPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 952
Score = 60.8 bits (146), Expect = 3e-08
Identities = 107/491 (21%), Positives = 169/491 (34%), Gaps = 56/491 (11%)
Query: 2165 TYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITK--FED 2222
T EPS + T P TP + T +P T + T EP TK
Sbjct: 414 TPKEPSPTTTKEPAPTTPKEPAPT----TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 469
Query: 2223 SEEISSSTYFPGSIIDYPEEISVSL-DRTAPPDGRASADHIVISLSDMASSIIESVVPK- 2280
+ + + T + P++++ + ++ AP A + ++A + E P
Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPTPTT 526
Query: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF 2340
PE P T + K+P KE E A KE A T + T
Sbjct: 527 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKET-APTTPKGTAPTTL 583
Query: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
P + P ++L+ T + +KPA P G+ + P +P P
Sbjct: 584 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAP 641
Query: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA-------- 2452
+ + P P P P P P L P T+ PT K +P TA
Sbjct: 642 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 701
Query: 2453 --TPLFDAVTTLETTAVLRSN-GLPVTRICTT----APPPVPPKPSSIPSGLVFTHRP-E 2504
TP A TT ET S P T T +P P+ S+ P+ + P E
Sbjct: 702 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE 761
Query: 2505 PSKPPI-APKPVIPQLPTTTQKPT---DIHPKPTGLSLTSSMTLNLVTSADY----KLPS 2556
P P P P++ TT + T D+ P + MT T+ + K+ +
Sbjct: 762 PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 821
Query: 2557 PTSPLSPHSNKSSPRF----------------SKSLTETYVVITLPSEPGTPTDSSASQA 2600
T+ ++ + + + F +K T ++ P E P D + +
Sbjct: 822 TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK 881
Query: 2601 ITSWPLGSPSK 2611
T+ P+K
Sbjct: 882 ATTPKPQKPTK 892
Score = 58.9 bits (141), Expect = 1e-07
Identities = 106/470 (22%), Positives = 154/470 (32%), Gaps = 74/470 (15%)
Query: 2169 PSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISS 2228
P E A + P P+ T + T ++P T + T EP K +E++
Sbjct: 543 PKEPAPTTPKEPAPT-TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 601
Query: 2229 STYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADT 2288
+T E S + D+ AP + +A PK P
Sbjct: 602 TTT--------KEPTSTTCDKPAPTTPKGTAP----------------TTPKEPAPT--- 634
Query: 2289 VSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDK---KELEAERTKSSLSETVFDHP-- 2343
+ K+P K T + E K KEL TK S T D P
Sbjct: 635 -------TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS-TTSDKPAP 686
Query: 2344 --PSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDI 2401
P KE TT T + P + +P+ + P S+ ++
Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746
Query: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-----VASPVTTATPLF 2456
SA+P P P P P P T P+ T K K T TTA P
Sbjct: 747 SAEPTPKALENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKM 803
Query: 2457 --DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
+ TT E T + TT P K +++ + +APK
Sbjct: 804 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT------------TTLAPKV 851
Query: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNL-VTSADYKLPS--PTSPLSPHSNKSSPR 2571
+ TT T+I KP + N T+ + P+ P P S K+ PR
Sbjct: 852 TTTKKTITT---TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 908
Query: 2572 FSK---SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEP 2618
K + T + T+P T + A T+ P +P+ LV V P
Sbjct: 909 VRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNP 958
Score = 50.1 bits (118), Expect = 6e-05
Identities = 100/525 (19%), Positives = 170/525 (32%), Gaps = 34/525 (6%)
Query: 1019 KRTETEKKP---PPIKDS--KSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKD- 1072
K+ T+KKP PP+ D L K P ST P T I +
Sbjct: 70 KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 129
Query: 1073 -PPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSG 1131
PPN +T E V N T T + + + + + + I K
Sbjct: 130 LPPNSDTSKETSLTV-NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188
Query: 1132 PKASPMPVPTESSSQKTAVP----PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPP 1187
P + + PT + T P P+ ++ T ++ +K + K P
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 1188 MVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKK 1247
TT K + + K+P P K E ++E P + PT +
Sbjct: 249 PTTTKSAPTTPK----EPAPTTTKEPAPTTPK---EPAPTTTKEPAPTTTKSAPTTPKEP 301
Query: 1248 LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLP 1307
K AP K + + + AP T + P T E P+ + P
Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTPK-EPAPTTKEPA--PTTPKEPAPTAPKKPAP 358
Query: 1308 KEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSS 1367
+ T ++P P T +P P ++ KS +++++P S
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEPSPTTP--KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 416
Query: 1368 DGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTL 1427
+ ++ E P + + +E +P++P + A + + A T
Sbjct: 417 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP------TTTKKPAPTT 470
Query: 1428 ADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDI 1487
E + T P E +P PK + T + E L T E+ + EE T ++
Sbjct: 471 PKEPA--PTTPKETAPTTPK--KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 526
Query: 1488 PSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTS 1532
P + P E + + P P + T+
Sbjct: 527 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 571
Score = 47.0 bits (110), Expect = 5e-04
Identities = 84/404 (20%), Positives = 142/404 (35%), Gaps = 62/404 (15%)
Query: 1062 CKTELNIGSKDPPNFNT-CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISG-QL 1119
C + K P++ + C E K+ N PTP + E A SG
Sbjct: 45 CDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPVVDE----------AGSGLDN 94
Query: 1120 GDIRKMPPAPSGPKASPMPVPTESSSQKTAVP-PQVKLVKKQEQEVKTEAEKVILEKVKE 1178
GD + P S + + + + ++ K P P + +E K + KE
Sbjct: 95 GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKE 154
Query: 1179 TLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPL-PEEKKLIPEEEKIRSEEKKPLLE 1237
T + K +TD K++ + ++ ++ K L P K L K + K P L
Sbjct: 155 TTTTNK---QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 211
Query: 1238 E-KKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKME 1296
K+PTP K E ++ P+E +KS P T E
Sbjct: 212 TPKEPTPTTPK---EPASTTPKEPTPTTIKSA----------------------PTTPKE 246
Query: 1297 GLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS 1356
P+ T K+ T ++P P T +P P + + + T++ P +
Sbjct: 247 PAPTTT---------KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 297
Query: 1357 PQGLSDTGYSSDGISSSLGEIPSL----IPTDEKDILKGLKKDSFSQESSPSSPSDLAKL 1412
P+ + T ++ P+ PT K+ K+ + ++P P+ A
Sbjct: 298 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA---PTTPKEPAPTAPK 354
Query: 1413 ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLS 1456
+ + E +T K T E SP PK+ T + S
Sbjct: 355 KPAPTTPKEPAPTT---PKEPAPTTTKEPSPTTPKEPAPTTTKS 395
Score = 46.6 bits (109), Expect = 6e-04
Identities = 65/287 (22%), Positives = 105/287 (36%), Gaps = 17/287 (5%)
Query: 3464 TKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAE 3523
TK++ T+ QT + +++ T S ++ + + + A +K L+K + A T
Sbjct: 152 TKETTTTNKQTSTDGKEK----TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 207
Query: 3524 ISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSA 3583
++ T T TP A K I + T K + A + + P +
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 267
Query: 3584 TSP-PKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLY----SPISPLSPGKALES 3638
P P K P P ++ A +T + AP+ PK P +P +P P
Sbjct: 268 KEPAPTTPKEPAPT----TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 323
Query: 3639 AFVPY--EKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSP-TADESSRA 3695
P ++P P P + A P P + + + PK +P T E S
Sbjct: 324 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 383
Query: 3696 PFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFST 3742
+ TTK + T T A K + P P E T T+ T
Sbjct: 384 TPKEPAPTTTKSAPTTTKEPAPTTTK-SAPTTPKEPSPTTTKEPAPT 429
Score = 40.8 bits (94), Expect = 0.035
Identities = 92/432 (21%), Positives = 151/432 (34%), Gaps = 68/432 (15%)
Query: 2165 TYSEPSESATSVP-PSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFE-- 2221
T EP+ + P P + T+ + T+D +P T ++ T EP K
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 710
Query: 2222 --------DSEEISS--STYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMAS 2271
+ E+S+ +T P +I P+E + L +A P +A + +
Sbjct: 711 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL--SAEPTPKA-----------LEN 757
Query: 2272 SIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERT 2331
S E VP + P A ++ + KD + T + ++ + T
Sbjct: 758 SPKEPGVPTTKTPAA--TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 815
Query: 2332 KSSL--------SETVFDHPPSSVIALP---MKEQLSTTYFTSGETFGQEKPASQLPSGS 2380
+S + S T D P + L + +++TT T T KP
Sbjct: 816 ESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET----- 870
Query: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPK 2440
AKP+ +S A P P P P P P +P PK T P+
Sbjct: 871 -------AKPKDRATNSK----ATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 919
Query: 2441 KKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP--PPVPPKPSSIPSGLV 2498
K + + + + +A+ L+TT R N P +++ P P L+
Sbjct: 920 KMTSTMPELNPTSRIAEAM--LQTTT--RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 975
Query: 2499 FTH------RPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPT-GLSLTSSMTLNLVTSAD 2551
H P+ P P I P + + + KP GL+ + TL
Sbjct: 976 RPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHY 1035
Query: 2552 YKLPSPTSPLSP 2563
+ + SP SP SP
Sbjct: 1036 FWMLSPFSPPSP 1047
Score = 39.3 bits (90), Expect = 0.10
Identities = 89/413 (21%), Positives = 145/413 (35%), Gaps = 63/413 (15%)
Query: 3582 SATSPPKDKKRPTPLEIGYSSHLRADSTV--QLAPSPPK--SPKVLYSPISPLSPGKALE 3637
+A + PK+ TP E ++ T + AP+ PK +P L P +P +P
Sbjct: 538 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP-APTTP----- 591
Query: 3638 SAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAK-MMQRSMSDPKPLSP--------- 3687
+KP P +++P P +P T K + +P P +P
Sbjct: 592 ------KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 645
Query: 3688 -TADESSRAPFQYT---------EGYTTKGSQTMTS-SGAQKKVKRTLPNPPPEEISTGT 3736
TA + + P T TTKG + TS A K T P P E T
Sbjct: 646 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 705
Query: 3737 QSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDA 3796
+ T +T K I + D + EL E
Sbjct: 706 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD----------ESTPELSAEPTPKAL 755
Query: 3797 KLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERP 3856
+ E G+ K + E A + +RD + E ++ P + E
Sbjct: 756 ENSPKEPGVPTTKTPAATKPEMTTTA--KDKTTERDLRTTPETTTAAPKMTK-----ETA 808
Query: 3857 RTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYH 3916
T +T S+ TQ S T+P ++ ++ T AP T + + +
Sbjct: 809 TTTEKTTESKITATTTQVTSTTTQDTTP---FKITTLKTTTLAPKVTTTKKTITTTEIMN 865
Query: 3917 QQVSPYQT-QPTFQAVATMSFTPQVQ-PTPTP-QPSYQLPSQMMVIQQKPRQT 3966
+ P +T +P +A + + TP+ Q PT P +P+ + M +KP+ T
Sbjct: 866 K---PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 915
Score = 34.7 bits (78), Expect = 2.5
Identities = 37/154 (24%), Positives = 52/154 (33%), Gaps = 20/154 (12%)
Query: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKAL-ESAFV 3641
A + PK TP E AP+ PK P +P +P P E A
Sbjct: 302 APTTPKKPAPTTPKE--------------PAPTTPKEP----TPTTPKEPAPTTKEPAPT 343
Query: 3642 PYEKPLPD-DISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYT 3700
++P P P + A P P + S + PK +PT +S+ +
Sbjct: 344 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 403
Query: 3701 EGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEIST 3734
TTK + T + K P P E T
Sbjct: 404 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 437
Score = 32.7 bits (73), Expect = 9.6
Identities = 39/168 (23%), Positives = 66/168 (39%), Gaps = 8/168 (4%)
Query: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVP 3642
A + PK+ TP E ++ + T P+P + + L+P + A
Sbjct: 443 APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT 502
Query: 3643 YEKP---LPDDISPQKVLHPDMAKVPPASPKTAK-MMQRSMSDPKPLSP--TADESSRAP 3696
EKP P++++P P +P T K + +P P +P A + + P
Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 562
Query: 3697 FQYTEGYTTKGSQTMTSSGAQKKVKRTLP-NPPPEEIS-TGTQSTFST 3742
T T + T+ K+ T P P P+E++ T T+ ST
Sbjct: 563 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST 610
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 176 bits (446), Expect = 5e-43
Identities = 227/923 (24%), Positives = 336/923 (36%), Gaps = 131/923 (14%)
Query: 94 KQSGRPP---DPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKS 150
K + +PP + G G K T DT ++ SP + K R L +
Sbjct: 118 KPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 177
Query: 151 SMMPGFL--SEVNALSAVSSVVNKFNPFD----------LISDSEASQEETTKKQKVVQK 198
S E + ++ NK D S + S ++ KV+ K
Sbjct: 178 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237
Query: 199 EQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ-------PEKIKSQP 251
K E K P P +P P ++ TP +I S P KS P
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297
Query: 252 PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ---TKQADIVRGESVK--PSLPSPSKPPI 306
+P T+ P K P P TK A E P P+P+ P
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357
Query: 307 QQPTPGKPPA----QQPGHEKSQPGPAKP----PAQPSGLTKPLAQQPGTVKPPVQPPGT 358
PT K P ++P +P P P P P ++P P P T
Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417
Query: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA----QQPGPAKPPTQQ 414
TK P+ P P +P T S ++++P P P K P+ ++P P P
Sbjct: 418 TKEPS-PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 476
Query: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474
TPK +P +P K P PT TP + P T+ ++ PT P P
Sbjct: 477 PTTPK----KPAPTTP-KEPAPT-TPKE-------------PAPTTTKKPAPTTPKE--P 515
Query: 475 GPAKPPPQQP-GPAKPPPQQPGSAKPPS-QQPGSTKP------PPQQPGPAKPSPQQPGS 526
P P P P K P P P + ++P T P P++P P +P++P
Sbjct: 516 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT--TPEEPAP 573
Query: 527 TKPPSQQPGSAKPSA----QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
T P + P + K A ++P+P P T P P P +P+ + P+
Sbjct: 574 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA----PTTPKGTAPTTLKEPAP 629
Query: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTE-CQTTVCSLCGFNP-NPHLTEVKEWLCLNC 640
PK P EL ++ TC + TT P P T KE
Sbjct: 630 TTPKKPAP----KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 685
Query: 641 Q--MKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA--APKQDLSK 696
+ L P P PK + AP TT S +S +P T+PK+ A PK+
Sbjct: 686 KGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 744
Query: 697 APE------PKKPPPL---VKQPTLHGSPSAKAKQPPEA--DSLSKPAP------PKEPS 739
P+ P+ PPP V PT P+ K P E+ + ++P P PKEP
Sbjct: 745 TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 804
Query: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDS 799
VP+ K P A +P+M D + T P+ ++ + E TT T+S
Sbjct: 805 VPT--TKTPAA----TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 858
Query: 800 ---AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
A +Q T + +PF + K+ ++ K + + K EE
Sbjct: 859 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKV------TTTKKTITTTEIMNKPEETA 912
Query: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTA---GQTVP---TPQQSPKPQEQSRRF-SLNL 909
K + + + P P+ PT +PT+ +T+P P+ +P P++ + LN
Sbjct: 913 KPKDRATNSKATTPKPQ-KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNP 971
Query: 910 GS-ITDAPKSQPTTPQETVTGKL 931
S I +A T P +T KL
Sbjct: 972 TSRIAEAMLQTTTRPNQTPNSKL 994
Score = 166 bits (421), Expect = 4e-40
Identities = 236/1014 (23%), Positives = 357/1014 (35%), Gaps = 168/1014 (16%)
Query: 348 TVKPPVQPPGTTKPPAQPL--GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405
T K P P L G K T + + + PK P P
Sbjct: 115 TKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP-------INP 167
Query: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG----KTSA 461
P+ PP T K + ++ + T T Q GK A KTSA
Sbjct: 168 RPSLPPNSD--TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA 225
Query: 462 QQTGPT---------KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512
+ PT K + GPA P++P P P ++P S P P + K P
Sbjct: 226 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTTIKSAPT 283
Query: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTV 572
P P+ + T P P + K A +P +P+ + +P T P P
Sbjct: 284 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEP 342
Query: 573 SPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEV 632
+P+ + P+ PK P P++ T E P P E
Sbjct: 343 APTTPKKPAPTTPKEPAPT---------TPKEPTPTTPKE------------PAPTTKE- 380
Query: 633 KEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ 692
P P++P+ TAP K +P T+PK+ P
Sbjct: 381 -------------------PAPTTPKEPAPTAPKKPAPTTPK---EPAPTTPKE---PAP 415
Query: 693 DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVA-- 750
+K P P P PT S K+P + S P PKEPS + ++ AP
Sbjct: 416 TTTKEPSPTTPKE--PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 473
Query: 751 DDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKT---TPPLKTDSAKPSQSFP 807
+ P PK PTT + + +P ++K + K T P +T P + P
Sbjct: 474 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 533
Query: 808 PTGEKVSPFDSKAIPRPASDSKII----SHPGPSSESKGQKQVDPVQKKEEPK------- 856
T EK++P + P P + ++ P P++ + PK
Sbjct: 534 TTPEKLAPTTPEK-PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592
Query: 857 KAQTKMSPKPDAKPMPKGSP--TPPGPRPTA-GQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
K +PK A PK + TP G PT + PT + P P+E + + S T
Sbjct: 593 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652
Query: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973
K PTTP+ T + + + P + P P K AP P
Sbjct: 653 -CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 711
Query: 974 PTSQGPPKSTGQ--APPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIK 1031
T++GP +T AP P ++ P + AP K + APT T + PPP
Sbjct: 712 TTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-----KPAPT-----TPETPPP-- 759
Query: 1032 DSKSLTAEPQKAVLPTKLEKSP---KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCN 1088
+ S + P PT + KSP PE + L K+P T T +
Sbjct: 760 -TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK--- 815
Query: 1089 LCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKT 1148
P +T + + T+R D+R P + A M T ++++KT
Sbjct: 816 -------PEMTTTAK----DKTTER-------DLRTTPETTTA--APKMTKETATTTEKT 855
Query: 1149 AVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ----------KQEES 1198
+ K+ Q T + K+ TL + P VTT + K EE+
Sbjct: 856 T---ESKITATTTQVTSTTTQDTTPFKI-TTLKTTTLAPKVTTTKKTITTTEIMNKPEET 911
Query: 1199 KLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK-KPLLEEKKPTPEDKKLLPEAKTSAP 1257
KD+A+ + P P++ P++ + K P + + K TP +K+ ++ P
Sbjct: 912 AKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKM----TSTMP 967
Query: 1258 EEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGK----QPQTKMEGLPSG-TPQSL 1306
E L +IAE L+ P K P+++ G G TP L
Sbjct: 968 E------LNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHML 1015
Score = 118 bits (295), Expect = 2e-25
Identities = 191/869 (21%), Positives = 301/869 (34%), Gaps = 150/869 (17%)
Query: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711
P P++P+ T P T KS+P T+PK + AP S PK+P P +
Sbjct: 257 PTPTTPKEPASTTPKEPTPTTIKSAP----TTPK-EPAPTTTKSAPTTPKEPAPTTTKEP 311
Query: 712 LHGSPSAKA----KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767
+P A K+P + S P PKEP+ + + AP +P +PT
Sbjct: 312 APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP 371
Query: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
+ TTK P++ E T P K P + P T ++ +P +K P P +
Sbjct: 372 KEPAPTTKEPAPTTP----KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE-PSPTTP 426
Query: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP-----TPPGPR 882
+ P P++ P KE P TK +P +P P + TP P
Sbjct: 427 KE----PAPTTTKSA-----PTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 476
Query: 883 PTAGQT-VPTPQQSPKPQ--EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF 939
PT + PT + P P ++ + + T + PTTP+ET
Sbjct: 477 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA------------ 524
Query: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKE 999
P + P P K AP + P P + P P + P +
Sbjct: 525 ------------PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 572
Query: 1000 TKAPAAEKLEPKAEQAPTVKRTE---TEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056
P A E APT + T K+P P ++ P K PT L K P P
Sbjct: 573 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTL-KEPAPT 630
Query: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116
+ EL + P TC + P P +
Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDK------------PAPTTPK---------------- 662
Query: 1117 GQLGDIRKMP--PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILE 1174
G P PAP+ PK P PT + K P +K + T +K +
Sbjct: 663 ---GTAPTTPKEPAPTTPKE---PAPT---TPKGTAPTTLK------EPAPTTPKKPAPK 707
Query: 1175 KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP 1234
++ T + K P T+D KP P P+E + ++
Sbjct: 708 ELAPTTT--KGPTSTTSD-------------------KPAPTT----PKETAPTTPKEPA 742
Query: 1235 LLEEKKPTPEDKKLLP----EAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEG-K 1289
KKP P + P E T ++ + KS + E L PK ++ K
Sbjct: 743 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE-LSAEPTPKALENSPK 801
Query: 1290 QPQTKMEGLPSGT-PQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDT 1348
+P P+ T P+ DKTT+ TA P + TEK + T
Sbjct: 802 EPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKIT 861
Query: 1349 SSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSD 1408
+++ Q S T + + ++ + + T +K I + ++ + P D
Sbjct: 862 ATTTQVTSTTTQDTTPFKITTLKTT--TLAPKVTTTKKTI---TTTEIMNKPEETAKPKD 916
Query: 1409 LAKLESTVLSILEAQASTLADEK----SEKKTQPHEVSPE-QPKDQEKTQSLSETLEITI 1463
A ++ + + Q T A +K + KT P P+ P ++ T ++ E +
Sbjct: 917 RA--TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR 974
Query: 1464 SEEEIKESQEERKDTFKKDSQQDIPSSKD 1492
E + ++ T + P S+D
Sbjct: 975 IAEAMLQTTTRPNQTPNSKLVEVNPKSED 1003
Score = 99.8 bits (247), Expect = 6e-20
Identities = 183/812 (22%), Positives = 276/812 (33%), Gaps = 137/812 (16%)
Query: 691 KQDLSKAPEPKKPPPLVKQ--------------PTLHGSPSAKAKQPPEADSLSKPAPPK 736
K K P PK PP+V + P + K P+ + +KP P+
Sbjct: 112 KNRTKKKPTPK--PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT-AKPINPR 168
Query: 737 EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLK 796
PS+P P +D + V T + + + TT + + + +EKTT
Sbjct: 169 -PSLP------PNSDTSKETSLTVNKETTVETKETTTT-----NKQTSTDGKEKTT---- 212
Query: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES--KGQKQVDPVQKKEE 854
SAK +QS EK S D A SK+++ P P +E+ KG P +
Sbjct: 213 --SAKETQSI----EKTSAKDL------APTSKVLAKPTPKAETTTKGPALTTPKEPTPT 260
Query: 855 PKKAQTKMSPKPDAKPMPKGSPTPPG-PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSIT 913
K +PK K +PT P P PT ++ PT + P P T
Sbjct: 261 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP--------------T 306
Query: 914 DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP 973
+ PTTP+E A ++ +T P + P P K AP +
Sbjct: 307 TTKEPAPTTPKEP---------APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357
Query: 974 PTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS 1033
P P + T P PA P KE AP K E APT KKP P
Sbjct: 358 PAPTTPKEPTPTTPKEPA---PTTKEP-APTTPK-----EPAPTAP-----KKPAPTTPK 403
Query: 1034 KSLTAEPQKAVLPTKLEKSPK-PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGF 1092
+ P++ T E SP P+ P +K+P T +
Sbjct: 404 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK------ 457
Query: 1093 NPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPP 1152
P+P T+ + + PAP+ PK P P + + T P
Sbjct: 458 EPSPTTTK---------EPAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKKP 507
Query: 1153 QVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKK 1212
K+ E +K+ T + EK+ P TT +K + E+ + +E
Sbjct: 508 APTTPKEPAPTTPKETAPTTPKKLTPT-TPEKLAP--TTPEKPAPTTPEELAPTTPEEPT 564
Query: 1213 PL-PEEKKLIPEEEKIRSEEKKPL-LEEKKPTPEDKK-----LLPEAKTSAPEEQKHDLL 1265
P PEE + + K+P K+P P K E + P+ L
Sbjct: 565 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 624
Query: 1266 KSQVQIAEEKLEGR-VAPKTVQE---------------GKQPQTKMEGLPSGTPQSLPKE 1309
K +K + +AP T +E G P T E P+ + P
Sbjct: 625 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT 684
Query: 1310 DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDG 1369
T T ++P P KP E T + S TS P +P+ + T
Sbjct: 685 PKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 742
Query: 1370 ISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLAD 1429
++ P+ T S ++ P+ + K L A+ + A
Sbjct: 743 PTTPKKPAPTTPETPPP------TTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 796
Query: 1430 EKSEKKT-QPHEVSPEQPKDQEKTQSLSETLE 1460
E S K+ P +P K + T + +T E
Sbjct: 797 ENSPKEPGVPTTKTPAATKPEMTTTAKDKTTE 828
Score = 91.7 bits (226), Expect = 2e-17
Identities = 179/818 (21%), Positives = 269/818 (32%), Gaps = 96/818 (11%)
Query: 2164 LTYSEPSESATSVPP-SDTPSLTS-SVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFE 2221
+T ++P S+PP SDT TS +V+ T ++ TT +T E + +
Sbjct: 159 ITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ 218
Query: 2222 DSEEISSSTYFPGS-IIDYPEEISVSLDR----TAP--PDGRASADHIVISLSDMASSII 2274
E+ S+ P S ++ P + + + T P P + + + + I
Sbjct: 219 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 278
Query: 2275 ESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSS 2334
+S P+ P A T + + K+P KE A KE TK
Sbjct: 279 KSAPTTPKEP-APTTTKSAPTTPKEPAPTTTKEP----------APTTPKEPAPTTTKEP 327
Query: 2335 LSETVFDHP--PSSVIALPMKEQLSTTYFTSGETFGQEK----PASQLPSGSPSVSSLPA 2388
T P P K+ TT T +E P P+ + P
Sbjct: 328 APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 387
Query: 2389 KPRPFFRSSSLDISAQPPPPPPPPPPPPP----PPPPPPPPPLPPPTSPKPTIL--PKKK 2442
+P P + + P P P P P P P P P P T PT P
Sbjct: 388 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447
Query: 2443 LTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHR 2502
T ++P T P TT E TT P P P +
Sbjct: 448 TTKSAPTTPKEP--SPTTTKEPAP-------------TTPKEPAPTTPK----------K 482
Query: 2503 PEPSKPPIAPKPVIPQ--LPTTTQKPTDIHPK---PTGLSLTSSMTLNLVTSADYKLPSP 2557
P P+ P P P P+ PTTT+KP PK PT T+ T +T + +P
Sbjct: 483 PAPTTPK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP 541
Query: 2558 TSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVE 2617
T+P P ++P T T P EP T +A+ P + K+
Sbjct: 542 TTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 599
Query: 2618 P--VFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVS 2675
P P TA P + T L+ + T P+ + APT+ + +T
Sbjct: 600 PKEPAPTTPKETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 654
Query: 2676 KTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPK 2735
K + + TAP+ + T P EP P+ L+ + PK
Sbjct: 655 KPAPTTPKGTAPTTP-KEPAPTTPKEPAP------TTPKGTAPTTLKEPAPTTPKKPAPK 707
Query: 2736 VEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETV 2795
TT K +++T D T E P+ ++ TP +E
Sbjct: 708 ELAPTTTK--GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 765
Query: 2796 TFVTCTASASYTTGTESLVGAEHAMTTPLQLTTS--KHAEPPYRIPS-----------DQ 2842
T T + + A TP L S + P + P+ D+
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 825
Query: 2843 VFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVTNGWTDSTVSQGITDGEVVDLST 2902
P + T T+ T + T ST +Q T ++ L T
Sbjct: 826 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 885
Query: 2903 TKSHRTVVTMDE--STSSVMTKIIEDEKPVDLTAGRRA 2938
T V T + +T+ +M K E KP D +A
Sbjct: 886 TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 923
Score = 70.1 bits (170), Expect = 5e-11
Identities = 113/523 (21%), Positives = 162/523 (30%), Gaps = 88/523 (16%)
Query: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPST 132
P E P+ +EL + P + + P+ P P K+ +T + + P+
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAPNTPKEPAPTTPKEPAP 597
Query: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192
+ KE TT K
Sbjct: 598 TTPKE------------------------------------------------PAPTTPK 609
Query: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252
+ +G +K P P KP PK+ P ++ T + P K P
Sbjct: 610 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP---TTTKEPTSTTCDKPAPTTPKGTAP 666
Query: 253 GTGK---PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
T K P P T P P T + + E + P+ +P
Sbjct: 667 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTSDKP 725
Query: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA 369
P P P K +P P P KP P T P T +P
Sbjct: 726 APTTPKETAPTTPK-EPAPTTP-------KKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 777
Query: 370 KPPAQQTGSEKPSSEQPGPKAL---AQPPGV--GKTPAQQPGPAKPPTQQVGTPKPLAQQ 424
K P + T S +P PKAL + PGV KTPA + T + L
Sbjct: 778 KSPDEST---PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTT 834
Query: 425 PGLQSPA-KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483
P + A K T T ++ KI A T+ Q T P K + P
Sbjct: 835 PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT 894
Query: 484 PGPA------KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
P++ K + +T P PQ+P A P++P STK P P
Sbjct: 895 TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA---PKKPTSTKKPKTMPRVR 951
Query: 538 KPSAQQPSPAK-PSAQQSTKPVSQTGSG--KPLQPPTVSPSAK 577
KP P+P K S P S+ + P +P++K
Sbjct: 952 KPKT-TPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 993
Score = 60.8 bits (146), Expect = 3e-08
Identities = 107/491 (21%), Positives = 169/491 (34%), Gaps = 56/491 (11%)
Query: 2165 TYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITK--FED 2222
T EPS + T P TP + T +P T + T EP TK
Sbjct: 455 TPKEPSPTTTKEPAPTTPKEPAPT----TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 510
Query: 2223 SEEISSSTYFPGSIIDYPEEISVSL-DRTAPPDGRASADHIVISLSDMASSIIESVVPK- 2280
+ + + T + P++++ + ++ AP A + ++A + E P
Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPTPTT 567
Query: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF 2340
PE P T + K+P KE E A KE A T + T
Sbjct: 568 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKET-APTTPKGTAPTTL 624
Query: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
P + P ++L+ T + +KPA P G+ + P +P P
Sbjct: 625 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAP 682
Query: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA-------- 2452
+ + P P P P P P L P T+ PT K +P TA
Sbjct: 683 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 742
Query: 2453 --TPLFDAVTTLETTAVLRSN-GLPVTRICTT----APPPVPPKPSSIPSGLVFTHRP-E 2504
TP A TT ET S P T T +P P+ S+ P+ + P E
Sbjct: 743 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE 802
Query: 2505 PSKPPI-APKPVIPQLPTTTQKPT---DIHPKPTGLSLTSSMTLNLVTSADY----KLPS 2556
P P P P++ TT + T D+ P + MT T+ + K+ +
Sbjct: 803 PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 862
Query: 2557 PTSPLSPHSNKSSPRF----------------SKSLTETYVVITLPSEPGTPTDSSASQA 2600
T+ ++ + + + F +K T ++ P E P D + +
Sbjct: 863 TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK 922
Query: 2601 ITSWPLGSPSK 2611
T+ P+K
Sbjct: 923 ATTPKPQKPTK 933
Score = 58.9 bits (141), Expect = 1e-07
Identities = 106/470 (22%), Positives = 154/470 (32%), Gaps = 74/470 (15%)
Query: 2169 PSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISS 2228
P E A + P P+ T + T ++P T + T EP K +E++
Sbjct: 584 PKEPAPTTPKEPAPT-TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 642
Query: 2229 STYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADT 2288
+T E S + D+ AP + +A PK P
Sbjct: 643 TTT--------KEPTSTTCDKPAPTTPKGTAP----------------TTPKEPAPT--- 675
Query: 2289 VSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDK---KELEAERTKSSLSETVFDHP-- 2343
+ K+P K T + E K KEL TK S T D P
Sbjct: 676 -------TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS-TTSDKPAP 727
Query: 2344 --PSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDI 2401
P KE TT T + P + +P+ + P S+ ++
Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787
Query: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-----VASPVTTATPLF 2456
SA+P P P P P P T P+ T K K T TTA P
Sbjct: 788 SAEPTPKALENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKM 844
Query: 2457 --DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
+ TT E T + TT P K +++ + +APK
Sbjct: 845 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT------------TTLAPKV 892
Query: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNL-VTSADYKLPS--PTSPLSPHSNKSSPR 2571
+ TT T+I KP + N T+ + P+ P P S K+ PR
Sbjct: 893 TTTKKTITT---TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 949
Query: 2572 FSK---SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEP 2618
K + T + T+P T + A T+ P +P+ LV V P
Sbjct: 950 VRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNP 999
Score = 50.1 bits (118), Expect = 6e-05
Identities = 100/525 (19%), Positives = 170/525 (32%), Gaps = 34/525 (6%)
Query: 1019 KRTETEKKP---PPIKDS--KSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKD- 1072
K+ T+KKP PP+ D L K P ST P T I +
Sbjct: 111 KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 170
Query: 1073 -PPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSG 1131
PPN +T E V N T T + + + + + + I K
Sbjct: 171 LPPNSDTSKETSLTV-NKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229
Query: 1132 PKASPMPVPTESSSQKTAVP----PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPP 1187
P + + PT + T P P+ ++ T ++ +K + K P
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 1188 MVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKK 1247
TT K + + K+P P K E ++E P + PT +
Sbjct: 290 PTTTKSAPTTPK----EPAPTTTKEPAPTTPK---EPAPTTTKEPAPTTTKSAPTTPKEP 342
Query: 1248 LLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLP 1307
K AP K + + + AP T + P T E P+ + P
Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPTPTTPK-EPAPTTKEPA--PTTPKEPAPTAPKKPAP 399
Query: 1308 KEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSS 1367
+ T ++P P T +P P ++ KS +++++P S
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEPSPTTP--KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 457
Query: 1368 DGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTL 1427
+ ++ E P + + +E +P++P + A + + A T
Sbjct: 458 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP------TTTKKPAPTT 511
Query: 1428 ADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDI 1487
E + T P E +P PK + T + E L T E+ + EE T ++
Sbjct: 512 PKEPA--PTTPKETAPTTPK--KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 567
Query: 1488 PSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTS 1532
P + P E + + P P + T+
Sbjct: 568 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 612
Score = 47.0 bits (110), Expect = 5e-04
Identities = 84/404 (20%), Positives = 142/404 (35%), Gaps = 62/404 (15%)
Query: 1062 CKTELNIGSKDPPNFNT-CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISG-QL 1119
C + K P++ + C E K+ N PTP + E A SG
Sbjct: 86 CDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPVVDE----------AGSGLDN 135
Query: 1120 GDIRKMPPAPSGPKASPMPVPTESSSQKTAVP-PQVKLVKKQEQEVKTEAEKVILEKVKE 1178
GD + P S + + + + ++ K P P + +E K + KE
Sbjct: 136 GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKE 195
Query: 1179 TLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPL-PEEKKLIPEEEKIRSEEKKPLLE 1237
T + K +TD K++ + ++ ++ K L P K L K + K P L
Sbjct: 196 TTTTNK---QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 252
Query: 1238 E-KKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKME 1296
K+PTP K E ++ P+E +KS P T E
Sbjct: 253 TPKEPTPTTPK---EPASTTPKEPTPTTIKSA----------------------PTTPKE 287
Query: 1297 GLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS 1356
P+ T K+ T ++P P T +P P + + + T++ P +
Sbjct: 288 PAPTTT---------KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 338
Query: 1357 PQGLSDTGYSSDGISSSLGEIPSL----IPTDEKDILKGLKKDSFSQESSPSSPSDLAKL 1412
P+ + T ++ P+ PT K+ K+ + ++P P+ A
Sbjct: 339 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA---PTTPKEPAPTAPK 395
Query: 1413 ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLS 1456
+ + E +T K T E SP PK+ T + S
Sbjct: 396 KPAPTTPKEPAPTT---PKEPAPTTTKEPSPTTPKEPAPTTTKS 436
Score = 46.6 bits (109), Expect = 6e-04
Identities = 65/287 (22%), Positives = 105/287 (36%), Gaps = 17/287 (5%)
Query: 3464 TKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAE 3523
TK++ T+ QT + +++ T S ++ + + + A +K L+K + A T
Sbjct: 193 TKETTTTNKQTSTDGKEK----TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 248
Query: 3524 ISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSA 3583
++ T T TP A K I + T K + A + + P +
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 308
Query: 3584 TSP-PKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLY----SPISPLSPGKALES 3638
P P K P P ++ A +T + AP+ PK P +P +P P
Sbjct: 309 KEPAPTTPKEPAPT----TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 364
Query: 3639 AFVPY--EKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSP-TADESSRA 3695
P ++P P P + A P P + + + PK +P T E S
Sbjct: 365 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 424
Query: 3696 PFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFST 3742
+ TTK + T T A K + P P E T T+ T
Sbjct: 425 TPKEPAPTTTKSAPTTTKEPAPTTTK-SAPTTPKEPSPTTTKEPAPT 470
Score = 40.8 bits (94), Expect = 0.035
Identities = 92/432 (21%), Positives = 151/432 (34%), Gaps = 68/432 (15%)
Query: 2165 TYSEPSESATSVP-PSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFE-- 2221
T EP+ + P P + T+ + T+D +P T ++ T EP K
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 751
Query: 2222 --------DSEEISS--STYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMAS 2271
+ E+S+ +T P +I P+E + L +A P +A + +
Sbjct: 752 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL--SAEPTPKA-----------LEN 798
Query: 2272 SIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERT 2331
S E VP + P A ++ + KD + T + ++ + T
Sbjct: 799 SPKEPGVPTTKTPAA--TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 856
Query: 2332 KSSL--------SETVFDHPPSSVIALP---MKEQLSTTYFTSGETFGQEKPASQLPSGS 2380
+S + S T D P + L + +++TT T T KP
Sbjct: 857 ESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET----- 911
Query: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPK 2440
AKP+ +S A P P P P P P +P PK T P+
Sbjct: 912 -------AKPKDRATNSK----ATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 960
Query: 2441 KKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP--PPVPPKPSSIPSGLV 2498
K + + + + +A+ L+TT R N P +++ P P L+
Sbjct: 961 KMTSTMPELNPTSRIAEAM--LQTTT--RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1016
Query: 2499 FTH------RPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPT-GLSLTSSMTLNLVTSAD 2551
H P+ P P I P + + + KP GL+ + TL
Sbjct: 1017 RPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHY 1076
Query: 2552 YKLPSPTSPLSP 2563
+ + SP SP SP
Sbjct: 1077 FWMLSPFSPPSP 1088
Score = 39.3 bits (90), Expect = 0.10
Identities = 89/413 (21%), Positives = 145/413 (35%), Gaps = 63/413 (15%)
Query: 3582 SATSPPKDKKRPTPLEIGYSSHLRADSTV--QLAPSPPK--SPKVLYSPISPLSPGKALE 3637
+A + PK+ TP E ++ T + AP+ PK +P L P +P +P
Sbjct: 579 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP-APTTP----- 632
Query: 3638 SAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAK-MMQRSMSDPKPLSP--------- 3687
+KP P +++P P +P T K + +P P +P
Sbjct: 633 ------KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 686
Query: 3688 -TADESSRAPFQYT---------EGYTTKGSQTMTS-SGAQKKVKRTLPNPPPEEISTGT 3736
TA + + P T TTKG + TS A K T P P E T
Sbjct: 687 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 746
Query: 3737 QSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDA 3796
+ T +T K I + D + EL E
Sbjct: 747 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD----------ESTPELSAEPTPKAL 796
Query: 3797 KLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERP 3856
+ E G+ K + E A + +RD + E ++ P + E
Sbjct: 797 ENSPKEPGVPTTKTPAATKPEMTTTA--KDKTTERDLRTTPETTTAAPKMTK-----ETA 849
Query: 3857 RTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYH 3916
T +T S+ TQ S T+P ++ ++ T AP T + + +
Sbjct: 850 TTTEKTTESKITATTTQVTSTTTQDTTP---FKITTLKTTTLAPKVTTTKKTITTTEIMN 906
Query: 3917 QQVSPYQT-QPTFQAVATMSFTPQVQ-PTPTP-QPSYQLPSQMMVIQQKPRQT 3966
+ P +T +P +A + + TP+ Q PT P +P+ + M +KP+ T
Sbjct: 907 K---PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 956
Score = 34.7 bits (78), Expect = 2.5
Identities = 37/154 (24%), Positives = 52/154 (33%), Gaps = 20/154 (12%)
Query: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKAL-ESAFV 3641
A + PK TP E AP+ PK P +P +P P E A
Sbjct: 343 APTTPKKPAPTTPKE--------------PAPTTPKEP----TPTTPKEPAPTTKEPAPT 384
Query: 3642 PYEKPLPD-DISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYT 3700
++P P P + A P P + S + PK +PT +S+ +
Sbjct: 385 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 444
Query: 3701 EGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEIST 3734
TTK + T + K P P E T
Sbjct: 445 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 478
Score = 32.7 bits (73), Expect = 9.6
Identities = 39/168 (23%), Positives = 66/168 (39%), Gaps = 8/168 (4%)
Query: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVP 3642
A + PK+ TP E ++ + T P+P + + L+P + A
Sbjct: 484 APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT 543
Query: 3643 YEKP---LPDDISPQKVLHPDMAKVPPASPKTAK-MMQRSMSDPKPLSP--TADESSRAP 3696
EKP P++++P P +P T K + +P P +P A + + P
Sbjct: 544 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 603
Query: 3697 FQYTEGYTTKGSQTMTSSGAQKKVKRTLP-NPPPEEIS-TGTQSTFST 3742
T T + T+ K+ T P P P+E++ T T+ ST
Sbjct: 604 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST 651
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 176 bits (446), Expect = 5e-43
Identities = 227/923 (24%), Positives = 336/923 (36%), Gaps = 131/923 (14%)
Query: 94 KQSGRPP---DPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKS 150
K + +PP + G G K T DT ++ SP + K R L +
Sbjct: 170 KPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 229
Query: 151 SMMPGFL--SEVNALSAVSSVVNKFNPFD----------LISDSEASQEETTKKQKVVQK 198
S E + ++ NK D S + S ++ KV+ K
Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289
Query: 199 EQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ-------PEKIKSQP 251
K E K P P +P P ++ TP +I S P KS P
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349
Query: 252 PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ---TKQADIVRGESVK--PSLPSPSKPPI 306
+P T+ P K P P TK A E P P+P+ P
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409
Query: 307 QQPTPGKPPA----QQPGHEKSQPGPAKP----PAQPSGLTKPLAQQPGTVKPPVQPPGT 358
PT K P ++P +P P P P P ++P P P T
Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469
Query: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA----QQPGPAKPPTQQ 414
TK P+ P P +P T S ++++P P P K P+ ++P P P
Sbjct: 470 TKEPS-PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 528
Query: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474
TPK +P +P K P PT TP + P T+ ++ PT P P
Sbjct: 529 PTTPK----KPAPTTP-KEPAPT-TPKE-------------PAPTTTKKPAPTTPKE--P 567
Query: 475 GPAKPPPQQP-GPAKPPPQQPGSAKPPS-QQPGSTKP------PPQQPGPAKPSPQQPGS 526
P P P P K P P P + ++P T P P++P P +P++P
Sbjct: 568 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT--TPEEPAP 625
Query: 527 TKPPSQQPGSAKPSA----QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
T P + P + K A ++P+P P T P P P +P+ + P+
Sbjct: 626 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA----PTTPKGTAPTTLKEPAP 681
Query: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTE-CQTTVCSLCGFNP-NPHLTEVKEWLCLNC 640
PK P EL ++ TC + TT P P T KE
Sbjct: 682 TTPKKPAP----KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 737
Query: 641 Q--MKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA--APKQDLSK 696
+ L P P PK + AP TT S +S +P T+PK+ A PK+
Sbjct: 738 KGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 796
Query: 697 APE------PKKPPPL---VKQPTLHGSPSAKAKQPPEA--DSLSKPAP------PKEPS 739
P+ P+ PPP V PT P+ K P E+ + ++P P PKEP
Sbjct: 797 TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 856
Query: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDS 799
VP+ K P A +P+M D + T P+ ++ + E TT T+S
Sbjct: 857 VPT--TKTPAA----TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 910
Query: 800 ---AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
A +Q T + +PF + K+ ++ K + + K EE
Sbjct: 911 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKV------TTTKKTITTTEIMNKPEETA 964
Query: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTA---GQTVP---TPQQSPKPQEQSRRF-SLNL 909
K + + + P P+ PT +PT+ +T+P P+ +P P++ + LN
Sbjct: 965 KPKDRATNSKATTPKPQ-KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNP 1023
Query: 910 GS-ITDAPKSQPTTPQETVTGKL 931
S I +A T P +T KL
Sbjct: 1024 TSRIAEAMLQTTTRPNQTPNSKL 1046
Score = 167 bits (423), Expect = 2e-40
Identities = 254/1132 (22%), Positives = 393/1132 (34%), Gaps = 183/1132 (16%)
Query: 225 PGRDPLQQDGTPKSISSQ---QPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281
P P + P S +SQ K +PP K + T+ + +++S
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128
Query: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL--- 338
+ + +K S S + +Q+ K + +K P P SGL
Sbjct: 129 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 188
Query: 339 ----TKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP 394
T P K P TT P P P+ PP T E +S + +
Sbjct: 189 DFKVTTPDTSTTQHNKVSTSPKITTAKPINPR-PSLPPNSDTSKE--TSLTVNKETTVET 245
Query: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454
T Q K T + + + + AK PT + +P P
Sbjct: 246 KETTTTNKQTSTDGKEKTTSAKETQSIEK-----TSAKDLAPTSKVLAKPTP-------- 292
Query: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514
K + GPA P++P P P ++P S P P + K P P
Sbjct: 293 -------------KAETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTTIKSAPTTP 337
Query: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574
P+ + T P P + K A +P +P+ + +P T P P +P
Sbjct: 338 KEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396
Query: 575 SAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKE 634
+ + P+ PK P P++ T E P P E
Sbjct: 397 TTPKKPAPTTPKEPAPT---------TPKEPTPTTPKE------------PAPTTKE--- 432
Query: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL 694
P P++P+ TAP K +P T+PK+ P
Sbjct: 433 -----------------PAPTTPKEPAPTAPKKPAPTTPK---EPAPTTPKE---PAPTT 469
Query: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVA--DD 752
+K P P P PT S K+P + S P PKEPS + ++ AP +
Sbjct: 470 TKEPSPTTPKE--PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 527
Query: 753 KPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKT---TPPLKTDSAKPSQSFPPT 809
P PK PTT + + +P ++K + K T P +T P + P T
Sbjct: 528 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587
Query: 810 GEKVSPFDSKAIPRPASDSKII----SHPGPSSESKGQKQVDPVQKKEEPK-------KA 858
EK++P + P P + ++ P P++ + PK K
Sbjct: 588 PEKLAPTTPEK-PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 646
Query: 859 QTKMSPKPDAKPMPKGSP--TPPGPRPTA-GQTVPTPQQSPKPQEQSRRFSLNLGSITDA 915
+PK A PK + TP G PT + PT + P P+E + + S T
Sbjct: 647 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT-C 705
Query: 916 PKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPT 975
K PTTP+ T + + + P + P P K AP P T
Sbjct: 706 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765
Query: 976 SQGPPKSTGQ--APPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS 1033
++GP +T AP P ++ P + AP K + APT T + PPP +
Sbjct: 766 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-----KPAPT-----TPETPPP---T 812
Query: 1034 KSLTAEPQKAVLPTKLEKSP---KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLC 1090
S + P PT + KSP PE + L K+P T T +
Sbjct: 813 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK----- 867
Query: 1091 GFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAV 1150
P +T + + T+R D+R P + A M T ++++KT
Sbjct: 868 -----PEMTTTAK----DKTTER-------DLRTTPETTTA--APKMTKETATTTEKTT- 908
Query: 1151 PPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ----------KQEESKL 1200
+ K+ Q T + K+ TL + P VTT + K EE+
Sbjct: 909 --ESKITATTTQVTSTTTQDTTPFKI-TTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 965
Query: 1201 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEK-KPLLEEKKPTPEDKKLLPEAKTSAPEE 1259
KD+A+ + P P++ P++ + K P + + K TP +K+ ++ PE
Sbjct: 966 PKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKM----TSTMPE- 1020
Query: 1260 QKHDLLKSQVQIAEEKLEGRVAPKTVQEGK----QPQTKMEGLPSG-TPQSL 1306
L +IAE L+ P K P+++ G G TP L
Sbjct: 1021 -----LNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHML 1067
Score = 120 bits (302), Expect = 3e-26
Identities = 237/1105 (21%), Positives = 372/1105 (33%), Gaps = 186/1105 (16%)
Query: 461 AQQTGPTKPPS--QLPGPAKPPPQQPGPAKPPPQQPGSAKPPS-------QQPGSTKPPP 511
A+ PT PPS + P P+ K P+ P K + S
Sbjct: 64 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ 123
Query: 512 QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP--------VSQTGS 563
+ + S K S + +A Q+ K + + TK V + GS
Sbjct: 124 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 183
Query: 564 G------KPLQPPT-------VSPSAKQPPSQGL-PKTICPLCNTTELLLHVPEKANFNT 609
G K P T VS S K ++ + P+ P + T +
Sbjct: 184 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV 243
Query: 610 CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP---VPSSPQPKLKTAPV 666
T+ TT + T KE +++ DLAP V + P PK +T
Sbjct: 244 ETKETTTTNKQTSTDGKEKTTSAKE----TQSIEKTSAKDLAPTSKVLAKPTPKAET--- 296
Query: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726
TT + +P T+PK+ A+ PK+P P T+ +P+ K+P
Sbjct: 297 TTKGPALTTPKEPTPTTPKEPASTT--------PKEPTPT----TIKSAPTTP-KEPAPT 343
Query: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786
+ S P PKEP+ + ++ AP +P +P S+ T K P
Sbjct: 344 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP------- 396
Query: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESK----G 842
T P K P + P T ++ +P K PA +K P P++ +
Sbjct: 397 -----TTPKKPAPTTPKEPAPTTPKEPTPTTPK---EPAPTTK---EPAPTTPKEPAPTA 445
Query: 843 QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902
K+ P KE + +P +P P TP P PT ++ PT + P P
Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT---TPKEPAPTTTKSAPTTTKEPAPT--- 499
Query: 903 RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGA 962
KS PTTP+E S + +T +P P + P
Sbjct: 500 ------------TTKSAPTTPKEP----------SPTTTKEPAPTTPKEPAPTTPKKPAP 537
Query: 963 PMKQAPAPSQP----PTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ--AP 1016
+ PAP+ P PT+ P T PAP KET +KL P + AP
Sbjct: 538 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT----TPKETAPTTPKKLTPTTPEKLAP 593
Query: 1017 TVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPK-PESTCPLCKTELNIGSKDPPN 1075
T T +KP P + P++ T E +P P++ P E + P
Sbjct: 594 T-----TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 648
Query: 1076 FNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKAS 1135
T E P P + +T PAP+ PK
Sbjct: 649 PTTPKE------------PAPTTPK---------ETAPTTPKGTAPTTLKEPAPTTPKK- 686
Query: 1136 PMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQ 1195
P P E + T P K K A E T P TT +
Sbjct: 687 --PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK----EPAPTTPKGT 740
Query: 1196 EESKLEKDKASALQEKKPLPEE-----------------KKLIPEEEKIRSEEKKPLLEE 1238
+ L++ + KKP P+E P+E + ++
Sbjct: 741 APTTLKEPAPTT--PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 798
Query: 1239 KKPTPEDKKLLP----EAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEG-KQPQT 1293
KKP P + P E T ++ + KS + E L PK ++ K+P
Sbjct: 799 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE-LSAEPTPKALENSPKEPGV 857
Query: 1294 KMEGLPSGT-PQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQ 1352
P+ T P+ DKTT+ TA P + TEK + T+++
Sbjct: 858 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 917
Query: 1353 QPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL 1412
Q S T + + ++ + + T +K I + ++ + P D A
Sbjct: 918 QVTSTTTQDTTPFKITTLKTT--TLAPKVTTTKKTI---TTTEIMNKPEETAKPKDRA-- 970
Query: 1413 ESTVLSILEAQASTLADEK----SEKKTQPHEVSPE-QPKDQEKTQSLSETLEITISEEE 1467
++ + + Q T A +K + KT P P+ P ++ T ++ E + E
Sbjct: 971 TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1030
Query: 1468 IKESQEERKDTFKKDSQQDIPSSKD 1492
+ ++ T + P S+D
Sbjct: 1031 MLQTTTRPNQTPNSKLVEVNPKSED 1055
Score = 92.0 bits (227), Expect = 1e-17
Identities = 203/952 (21%), Positives = 313/952 (32%), Gaps = 140/952 (14%)
Query: 2078 PGSSPTQAPIGEDMT--ESTMDFDRMPDASLTSSVLSGASLTD--STSSATLSIPDVKIT 2133
P S P G T +T + P+ T V+ +T+ S S S +
Sbjct: 73 PSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 132
Query: 2134 QHFST-EEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSS-- 2190
ST +I+ + RE+Q+ L + ++ T P+ P + S
Sbjct: 133 SSSSTIRKIKSSKNSAANRELQKK-------LKVKDNKKNRTKKKPTPKPPVVDEAGSGL 185
Query: 2191 ------VCTTDSSSP----ITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYP 2240
V T D+S+ ++T ITT +P++ + + S T +
Sbjct: 186 DNGDFKVTTPDTSTTQHNKVSTSPKITTA--KPINPRPSLPPNSDTSKETS-----LTVN 238
Query: 2241 EEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDP 2300
+E +V T + + S D + S + IE K P + ++ P
Sbjct: 239 KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--------P 290
Query: 2301 VKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPM--KEQLST 2358
KA+ T A KE K S T + P+++ + P KE T
Sbjct: 291 TPKAETTTKG-------PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 343
Query: 2359 TYFTSGETFGQEKPASQLPSGSPSVSSLPA-----KPRPFFRSSSLDISAQPPPPPPPPP 2413
T S T +E + +P+ PA +P P S+ +P P P P
Sbjct: 344 TT-KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 402
Query: 2414 ----PPPPPP----------------------------PPPPPPPLPPPTSPK---PTIL 2438
P P P P P P P PT+PK PT
Sbjct: 403 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 462
Query: 2439 PKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLV 2498
+ T + TP A TT ++ P T T + P P +PS +
Sbjct: 463 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEPSPTTTKEP 519
Query: 2499 FTHRPE------PSKP----PIAPKPVIPQ--LPTTTQKPTDIHPK---PTGLSLTSSMT 2543
P+ P KP P P P P+ PTTT+KP PK PT T+ T
Sbjct: 520 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 579
Query: 2544 LNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITS 2603
+T + +PT+P P ++P T T P EP T +A+
Sbjct: 580 PKKLTPTTPEKLAPTTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 637
Query: 2604 WPLGSPSKDLVSVEP--VFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQA 2661
P + K+ P P TA P + T L+ + T P+ +
Sbjct: 638 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKEL 692
Query: 2662 APTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKL 2721
APT+ + +T K + + TAP+ + T P EP P+ L
Sbjct: 693 APTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPAPTTPKEPAP------TTPKGTAPTTL 745
Query: 2722 QLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVT 2781
+ + PK TT K +++T D T E P+
Sbjct: 746 KEPAPTTPKKPAPKELAPTTTK--GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803
Query: 2782 SSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAMTTPLQLTTS--KHAEPPYRIP 2839
++ TP +E T T + + A TP L S + P + P
Sbjct: 804 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 863
Query: 2840 S-----------DQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVTNGWTDSTV 2888
+ D+ P + T T+ T + T ST
Sbjct: 864 AATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTT 923
Query: 2889 SQGITDGEVVDLSTTKSHRTVVTMDE--STSSVMTKIIEDEKPVDLTAGRRA 2938
+Q T ++ L TT V T + +T+ +M K E KP D +A
Sbjct: 924 TQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 975
Score = 70.1 bits (170), Expect = 5e-11
Identities = 113/523 (21%), Positives = 162/523 (30%), Gaps = 88/523 (16%)
Query: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPST 132
P E P+ +EL + P + + P+ P P K+ +T + + P+
Sbjct: 593 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAPNTPKEPAPTTPKEPAP 649
Query: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192
+ KE TT K
Sbjct: 650 TTPKE------------------------------------------------PAPTTPK 661
Query: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252
+ +G +K P P KP PK+ P ++ T + P K P
Sbjct: 662 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP---TTTKEPTSTTCDKPAPTTPKGTAP 718
Query: 253 GTGK---PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
T K P P T P P T + + E + P+ +P
Sbjct: 719 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTSDKP 777
Query: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA 369
P P P K +P P P KP P T P T +P
Sbjct: 778 APTTPKETAPTTPK-EPAPTTP-------KKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 829
Query: 370 KPPAQQTGSEKPSSEQPGPKAL---AQPPGV--GKTPAQQPGPAKPPTQQVGTPKPLAQQ 424
K P + T S +P PKAL + PGV KTPA + T + L
Sbjct: 830 KSPDEST---PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTT 886
Query: 425 PGLQSPA-KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483
P + A K T T ++ KI A T+ Q T P K + P
Sbjct: 887 PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT 946
Query: 484 PGPA------KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
P++ K + +T P PQ+P A P++P STK P P
Sbjct: 947 TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA---PKKPTSTKKPKTMPRVR 1003
Query: 538 KPSAQQPSPAK-PSAQQSTKPVSQTGSG--KPLQPPTVSPSAK 577
KP P+P K S P S+ + P +P++K
Sbjct: 1004 KPKT-TPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 1045
Score = 60.8 bits (146), Expect = 3e-08
Identities = 107/491 (21%), Positives = 169/491 (34%), Gaps = 56/491 (11%)
Query: 2165 TYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITK--FED 2222
T EPS + T P TP + T +P T + T EP TK
Sbjct: 507 TPKEPSPTTTKEPAPTTPKEPAPT----TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 562
Query: 2223 SEEISSSTYFPGSIIDYPEEISVSL-DRTAPPDGRASADHIVISLSDMASSIIESVVPK- 2280
+ + + T + P++++ + ++ AP A + ++A + E P
Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPTPTT 619
Query: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF 2340
PE P T + K+P KE E A KE A T + T
Sbjct: 620 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKET-APTTPKGTAPTTL 676
Query: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
P + P ++L+ T + +KPA P G+ + P +P P
Sbjct: 677 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAP 734
Query: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA-------- 2452
+ + P P P P P P L P T+ PT K +P TA
Sbjct: 735 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 794
Query: 2453 --TPLFDAVTTLETTAVLRSN-GLPVTRICTT----APPPVPPKPSSIPSGLVFTHRP-E 2504
TP A TT ET S P T T +P P+ S+ P+ + P E
Sbjct: 795 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE 854
Query: 2505 PSKPPI-APKPVIPQLPTTTQKPT---DIHPKPTGLSLTSSMTLNLVTSADY----KLPS 2556
P P P P++ TT + T D+ P + MT T+ + K+ +
Sbjct: 855 PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 914
Query: 2557 PTSPLSPHSNKSSPRF----------------SKSLTETYVVITLPSEPGTPTDSSASQA 2600
T+ ++ + + + F +K T ++ P E P D + +
Sbjct: 915 TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK 974
Query: 2601 ITSWPLGSPSK 2611
T+ P+K
Sbjct: 975 ATTPKPQKPTK 985
Score = 58.9 bits (141), Expect = 1e-07
Identities = 106/470 (22%), Positives = 154/470 (32%), Gaps = 74/470 (15%)
Query: 2169 PSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISS 2228
P E A + P P+ T + T ++P T + T EP K +E++
Sbjct: 636 PKEPAPTTPKEPAPT-TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 694
Query: 2229 STYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADT 2288
+T E S + D+ AP + +A PK P
Sbjct: 695 TTT--------KEPTSTTCDKPAPTTPKGTAP----------------TTPKEPAPT--- 727
Query: 2289 VSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDK---KELEAERTKSSLSETVFDHP-- 2343
+ K+P K T + E K KEL TK S T D P
Sbjct: 728 -------TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS-TTSDKPAP 779
Query: 2344 --PSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDI 2401
P KE TT T + P + +P+ + P S+ ++
Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839
Query: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-----VASPVTTATPLF 2456
SA+P P P P P P T P+ T K K T TTA P
Sbjct: 840 SAEPTPKALENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKM 896
Query: 2457 --DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
+ TT E T + TT P K +++ + +APK
Sbjct: 897 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT------------TTLAPKV 944
Query: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNL-VTSADYKLPS--PTSPLSPHSNKSSPR 2571
+ TT T+I KP + N T+ + P+ P P S K+ PR
Sbjct: 945 TTTKKTITT---TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 1001
Query: 2572 FSK---SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEP 2618
K + T + T+P T + A T+ P +P+ LV V P
Sbjct: 1002 VRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNP 1051
Score = 57.4 bits (137), Expect = 4e-07
Identities = 111/597 (18%), Positives = 196/597 (32%), Gaps = 34/597 (5%)
Query: 947 STAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
+T P P ++ ++ + S+ S+ + + + +I K +K AA
Sbjct: 91 TTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAAN 150
Query: 1007 KLEPKAEQAPTVKRTETEKKP---PPIKDS--KSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
+ K + K+ T+KKP PP+ D L K P ST P
Sbjct: 151 RELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK 210
Query: 1062 CKTELNIGSKD--PPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQL 1119
T I + PPN +T E V N T T + + + + + +
Sbjct: 211 ITTAKPINPRPSLPPNSDTSKETSLTV-NKETTVETKETTTTNKQTSTDGKEKTTSAKET 269
Query: 1120 GDIRKMPPAPSGPKASPMPVPTESSSQKTAVP----PQVKLVKKQEQEVKTEAEKVILEK 1175
I K P + + PT + T P P+ ++ T ++
Sbjct: 270 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 329
Query: 1176 VKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPL 1235
+K + K P TT K + + K+P P K E ++E P
Sbjct: 330 IKSAPTTPKEPAPTTTKSAPTTPK----EPAPTTTKEPAPTTPK---EPAPTTTKEPAPT 382
Query: 1236 LEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKM 1295
+ PT + K AP K + + + AP T + P T
Sbjct: 383 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK-EPAPTTKEPA--PTTPK 439
Query: 1296 EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355
E P+ + P + T ++P P T +P P ++ KS +++++P
Sbjct: 440 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP--KEPAPTTTKSAPTTTKEPA 497
Query: 1356 SPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLEST 1415
S + ++ E P + + +E +P++P + A
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP---- 553
Query: 1416 VLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEER 1475
+ + A T E + T P E +P PK + T + E L T E+ + EE
Sbjct: 554 --TTTKKPAPTTPKEPA--PTTPKETAPTTPK--KLTPTTPEKLAPTTPEKPAPTTPEEL 607
Query: 1476 KDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTS 1532
T ++ P + P E + + P P + T+
Sbjct: 608 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 664
Score = 46.6 bits (109), Expect = 6e-04
Identities = 65/287 (22%), Positives = 105/287 (36%), Gaps = 17/287 (5%)
Query: 3464 TKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAE 3523
TK++ T+ QT + +++ T S ++ + + + A +K L+K + A T
Sbjct: 245 TKETTTTNKQTSTDGKEK----TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 300
Query: 3524 ISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSA 3583
++ T T TP A K I + T K + A + + P +
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 360
Query: 3584 TSP-PKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLY----SPISPLSPGKALES 3638
P P K P P ++ A +T + AP+ PK P +P +P P
Sbjct: 361 KEPAPTTPKEPAPT----TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 416
Query: 3639 AFVPY--EKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSP-TADESSRA 3695
P ++P P P + A P P + + + PK +P T E S
Sbjct: 417 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 476
Query: 3696 PFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFST 3742
+ TTK + T T A K + P P E T T+ T
Sbjct: 477 TPKEPAPTTTKSAPTTTKEPAPTTTK-SAPTTPKEPSPTTTKEPAPT 522
Score = 40.8 bits (94), Expect = 0.035
Identities = 92/432 (21%), Positives = 151/432 (34%), Gaps = 68/432 (15%)
Query: 2165 TYSEPSESATSVP-PSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFE-- 2221
T EP+ + P P + T+ + T+D +P T ++ T EP K
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803
Query: 2222 --------DSEEISS--STYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMAS 2271
+ E+S+ +T P +I P+E + L +A P +A + +
Sbjct: 804 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL--SAEPTPKA-----------LEN 850
Query: 2272 SIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERT 2331
S E VP + P A ++ + KD + T + ++ + T
Sbjct: 851 SPKEPGVPTTKTPAA--TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 908
Query: 2332 KSSL--------SETVFDHPPSSVIALP---MKEQLSTTYFTSGETFGQEKPASQLPSGS 2380
+S + S T D P + L + +++TT T T KP
Sbjct: 909 ESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET----- 963
Query: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPK 2440
AKP+ +S A P P P P P P +P PK T P+
Sbjct: 964 -------AKPKDRATNSK----ATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1012
Query: 2441 KKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP--PPVPPKPSSIPSGLV 2498
K + + + + +A+ L+TT R N P +++ P P L+
Sbjct: 1013 KMTSTMPELNPTSRIAEAM--LQTTT--RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1068
Query: 2499 FTH------RPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPT-GLSLTSSMTLNLVTSAD 2551
H P+ P P I P + + + KP GL+ + TL
Sbjct: 1069 RPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHY 1128
Query: 2552 YKLPSPTSPLSP 2563
+ + SP SP SP
Sbjct: 1129 FWMLSPFSPPSP 1140
Score = 39.3 bits (90), Expect = 0.10
Identities = 100/467 (21%), Positives = 159/467 (34%), Gaps = 91/467 (19%)
Query: 3547 VEIIKHISAPEKTYKGG---SLGCQTEADSDTQSPQY--------------LSATSPPKD 3589
V +I+ +S+ E + KG S E D D Q +Y + TSPP
Sbjct: 16 VFVIQQVSSQELSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSS 75
Query: 3590 KKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPD 3649
KK P P G S ++ ST + +P PP K K +ES + E + +
Sbjct: 76 KKAPPP--SGASQTIK--STTKRSPKPPNKKKT----------KKVIESEEITEEHSVSE 121
Query: 3650 D----------ISPQKVLHPDMAKVPPASPKTAKMMQ-------RSMSDPKPLSPTADES 3692
+ S + +K A+ + K ++ R+ P P P DE+
Sbjct: 122 NQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEA 181
Query: 3693 ----SRAPFQYT--EGYTTKGSQTMTSS--GAQKKVKRTLPNPPPEEISTGTQSTFSTMG 3744
F+ T + TT+ ++ TS K + PP + S T T +
Sbjct: 182 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 241
Query: 3745 TVSRRRICRTN--TMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLE 3802
TV + TN T K +E +E+ SAK +L K + E
Sbjct: 242 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK------DLAPTSKVLAKPTPKAE 295
Query: 3803 MGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERPRTAPQT 3862
+ AL +E + E +ST P P T
Sbjct: 296 --TTTKGPALTTPKEPTP-------------TTPKEPASTTPKE-------PTPTTIKSA 333
Query: 3863 EFSQFIPPQTQTESQLVPPTSPY-TQYQYSSPALPTQ-APTSYTQQSHFEQQTLYHQQVS 3920
+ P T T+S P P T + +P P + APT+ + + T +
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPTT 390
Query: 3921 PYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQKPRQTT 3967
P + PT + + PT +P+ P + ++P TT
Sbjct: 391 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 437
Score = 39.3 bits (90), Expect = 0.10
Identities = 89/413 (21%), Positives = 145/413 (35%), Gaps = 63/413 (15%)
Query: 3582 SATSPPKDKKRPTPLEIGYSSHLRADSTV--QLAPSPPK--SPKVLYSPISPLSPGKALE 3637
+A + PK+ TP E ++ T + AP+ PK +P L P +P +P
Sbjct: 631 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP-APTTP----- 684
Query: 3638 SAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAK-MMQRSMSDPKPLSP--------- 3687
+KP P +++P P +P T K + +P P +P
Sbjct: 685 ------KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 738
Query: 3688 -TADESSRAPFQYT---------EGYTTKGSQTMTS-SGAQKKVKRTLPNPPPEEISTGT 3736
TA + + P T TTKG + TS A K T P P E T
Sbjct: 739 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 798
Query: 3737 QSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDA 3796
+ T +T K I + D + EL E
Sbjct: 799 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD----------ESTPELSAEPTPKAL 848
Query: 3797 KLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERP 3856
+ E G+ K + E A + +RD + E ++ P + E
Sbjct: 849 ENSPKEPGVPTTKTPAATKPEMTTTA--KDKTTERDLRTTPETTTAAPKMTK-----ETA 901
Query: 3857 RTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYH 3916
T +T S+ TQ S T+P ++ ++ T AP T + + +
Sbjct: 902 TTTEKTTESKITATTTQVTSTTTQDTTP---FKITTLKTTTLAPKVTTTKKTITTTEIMN 958
Query: 3917 QQVSPYQT-QPTFQAVATMSFTPQVQ-PTPTP-QPSYQLPSQMMVIQQKPRQT 3966
+ P +T +P +A + + TP+ Q PT P +P+ + M +KP+ T
Sbjct: 959 K---PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 1008
Score = 34.7 bits (78), Expect = 2.5
Identities = 37/154 (24%), Positives = 52/154 (33%), Gaps = 20/154 (12%)
Query: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKAL-ESAFV 3641
A + PK TP E AP+ PK P +P +P P E A
Sbjct: 395 APTTPKKPAPTTPKE--------------PAPTTPKEP----TPTTPKEPAPTTKEPAPT 436
Query: 3642 PYEKPLPD-DISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYT 3700
++P P P + A P P + S + PK +PT +S+ +
Sbjct: 437 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 496
Query: 3701 EGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEIST 3734
TTK + T + K P P E T
Sbjct: 497 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 530
Score = 32.7 bits (73), Expect = 9.6
Identities = 39/168 (23%), Positives = 66/168 (39%), Gaps = 8/168 (4%)
Query: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVP 3642
A + PK+ TP E ++ + T P+P + + L+P + A
Sbjct: 536 APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT 595
Query: 3643 YEKP---LPDDISPQKVLHPDMAKVPPASPKTAK-MMQRSMSDPKPLSP--TADESSRAP 3696
EKP P++++P P +P T K + +P P +P A + + P
Sbjct: 596 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 655
Query: 3697 FQYTEGYTTKGSQTMTSSGAQKKVKRTLP-NPPPEEIS-TGTQSTFST 3742
T T + T+ K+ T P P P+E++ T T+ ST
Sbjct: 656 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST 703
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 176 bits (446), Expect = 5e-43
Identities = 227/923 (24%), Positives = 336/923 (36%), Gaps = 131/923 (14%)
Query: 94 KQSGRPP---DPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKS 150
K + +PP + G G K T DT ++ SP + K R L +
Sbjct: 211 KPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 270
Query: 151 SMMPGFL--SEVNALSAVSSVVNKFNPFD----------LISDSEASQEETTKKQKVVQK 198
S E + ++ NK D S + S ++ KV+ K
Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330
Query: 199 EQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ-------PEKIKSQP 251
K E K P P +P P ++ TP +I S P KS P
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390
Query: 252 PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ---TKQADIVRGESVK--PSLPSPSKPPI 306
+P T+ P K P P TK A E P P+P+ P
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450
Query: 307 QQPTPGKPPA----QQPGHEKSQPGPAKP----PAQPSGLTKPLAQQPGTVKPPVQPPGT 358
PT K P ++P +P P P P P ++P P P T
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510
Query: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA----QQPGPAKPPTQQ 414
TK P+ P P +P T S ++++P P P K P+ ++P P P
Sbjct: 511 TKEPS-PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 569
Query: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474
TPK +P +P K P PT TP + P T+ ++ PT P P
Sbjct: 570 PTTPK----KPAPTTP-KEPAPT-TPKE-------------PAPTTTKKPAPTTPKE--P 608
Query: 475 GPAKPPPQQP-GPAKPPPQQPGSAKPPS-QQPGSTKP------PPQQPGPAKPSPQQPGS 526
P P P P K P P P + ++P T P P++P P +P++P
Sbjct: 609 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT--TPEEPAP 666
Query: 527 TKPPSQQPGSAKPSA----QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
T P + P + K A ++P+P P T P P P +P+ + P+
Sbjct: 667 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA----PTTPKGTAPTTLKEPAP 722
Query: 583 GLPKTICPLCNTTELLLHVPEKANFNTCTE-CQTTVCSLCGFNP-NPHLTEVKEWLCLNC 640
PK P EL ++ TC + TT P P T KE
Sbjct: 723 TTPKKPAP----KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 778
Query: 641 Q--MKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA--APKQDLSK 696
+ L P P PK + AP TT S +S +P T+PK+ A PK+
Sbjct: 779 KGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPT 837
Query: 697 APE------PKKPPPL---VKQPTLHGSPSAKAKQPPEA--DSLSKPAP------PKEPS 739
P+ P+ PPP V PT P+ K P E+ + ++P P PKEP
Sbjct: 838 TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG 897
Query: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDS 799
VP+ K P A +P+M D + T P+ ++ + E TT T+S
Sbjct: 898 VPT--TKTPAA----TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 951
Query: 800 ---AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
A +Q T + +PF + K+ ++ K + + K EE
Sbjct: 952 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKV------TTTKKTITTTEIMNKPEETA 1005
Query: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTA---GQTVP---TPQQSPKPQEQSRRF-SLNL 909
K + + + P P+ PT +PT+ +T+P P+ +P P++ + LN
Sbjct: 1006 KPKDRATNSKATTPKPQ-KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNP 1064
Query: 910 GS-ITDAPKSQPTTPQETVTGKL 931
S I +A T P +T KL
Sbjct: 1065 TSRIAEAMLQTTTRPNQTPNSKL 1087
Score = 167 bits (423), Expect = 2e-40
Identities = 254/1132 (22%), Positives = 393/1132 (34%), Gaps = 183/1132 (16%)
Query: 225 PGRDPLQQDGTPKSISSQ---QPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281
P P + P S +SQ K +PP K + T+ + +++S
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 169
Query: 282 QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL--- 338
+ + +K S S + +Q+ K + +K P P SGL
Sbjct: 170 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 229
Query: 339 ----TKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP 394
T P K P TT P P P+ PP T E +S + +
Sbjct: 230 DFKVTTPDTSTTQHNKVSTSPKITTAKPINPR-PSLPPNSDTSKE--TSLTVNKETTVET 286
Query: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454
T Q K T + + + + AK PT + +P P
Sbjct: 287 KETTTTNKQTSTDGKEKTTSAKETQSIEK-----TSAKDLAPTSKVLAKPTP-------- 333
Query: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514
K + GPA P++P P P ++P S P P + K P P
Sbjct: 334 -------------KAETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTTIKSAPTTP 378
Query: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574
P+ + T P P + K A +P +P+ + +P T P P +P
Sbjct: 379 KEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437
Query: 575 SAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKE 634
+ + P+ PK P P++ T E P P E
Sbjct: 438 TTPKKPAPTTPKEPAPT---------TPKEPTPTTPKE------------PAPTTKE--- 473
Query: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL 694
P P++P+ TAP K +P T+PK+ P
Sbjct: 474 -----------------PAPTTPKEPAPTAPKKPAPTTPK---EPAPTTPKE---PAPTT 510
Query: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVA--DD 752
+K P P P PT S K+P + S P PKEPS + ++ AP +
Sbjct: 511 TKEPSPTTPKE--PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 568
Query: 753 KPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKT---TPPLKTDSAKPSQSFPPT 809
P PK PTT + + +P ++K + K T P +T P + P T
Sbjct: 569 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628
Query: 810 GEKVSPFDSKAIPRPASDSKII----SHPGPSSESKGQKQVDPVQKKEEPK-------KA 858
EK++P + P P + ++ P P++ + PK K
Sbjct: 629 PEKLAPTTPEK-PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 687
Query: 859 QTKMSPKPDAKPMPKGSP--TPPGPRPTA-GQTVPTPQQSPKPQEQSRRFSLNLGSITDA 915
+PK A PK + TP G PT + PT + P P+E + + S T
Sbjct: 688 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT-C 746
Query: 916 PKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPT 975
K PTTP+ T + + + P + P P K AP P T
Sbjct: 747 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806
Query: 976 SQGPPKSTGQ--APPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS 1033
++GP +T AP P ++ P + AP K + APT T + PPP +
Sbjct: 807 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK-----KPAPT-----TPETPPP---T 853
Query: 1034 KSLTAEPQKAVLPTKLEKSP---KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLC 1090
S + P PT + KSP PE + L K+P T T +
Sbjct: 854 TSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATK----- 908
Query: 1091 GFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAV 1150
P +T + + T+R D+R P + A M T ++++KT
Sbjct: 909 -----PEMTTTAK----DKTTER-------DLRTTPETTTA--APKMTKETATTTEKTT- 949
Query: 1151 PPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ----------KQEESKL 1200
+ K+ Q T + K+ TL + P VTT + K EE+
Sbjct: 950 --ESKITATTTQVTSTTTQDTTPFKI-TTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 1006
Query: 1201 EKDKASALQEKKPLPEEKKLIPEEEKIRSEEK-KPLLEEKKPTPEDKKLLPEAKTSAPEE 1259
KD+A+ + P P++ P++ + K P + + K TP +K+ ++ PE
Sbjct: 1007 PKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKM----TSTMPE- 1061
Query: 1260 QKHDLLKSQVQIAEEKLEGRVAPKTVQEGK----QPQTKMEGLPSG-TPQSL 1306
L +IAE L+ P K P+++ G G TP L
Sbjct: 1062 -----LNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHML 1108
Score = 120 bits (302), Expect = 3e-26
Identities = 237/1105 (21%), Positives = 372/1105 (33%), Gaps = 186/1105 (16%)
Query: 461 AQQTGPTKPPS--QLPGPAKPPPQQPGPAKPPPQQPGSAKPPS-------QQPGSTKPPP 511
A+ PT PPS + P P+ K P+ P K + S
Sbjct: 105 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQ 164
Query: 512 QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP--------VSQTGS 563
+ + S K S + +A Q+ K + + TK V + GS
Sbjct: 165 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 224
Query: 564 G------KPLQPPT-------VSPSAKQPPSQGL-PKTICPLCNTTELLLHVPEKANFNT 609
G K P T VS S K ++ + P+ P + T +
Sbjct: 225 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV 284
Query: 610 CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAP---VPSSPQPKLKTAPV 666
T+ TT + T KE +++ DLAP V + P PK +T
Sbjct: 285 ETKETTTTNKQTSTDGKEKTTSAKE----TQSIEKTSAKDLAPTSKVLAKPTPKAET--- 337
Query: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726
TT + +P T+PK+ A+ PK+P P T+ +P+ K+P
Sbjct: 338 TTKGPALTTPKEPTPTTPKEPASTT--------PKEPTPT----TIKSAPTTP-KEPAPT 384
Query: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786
+ S P PKEP+ + ++ AP +P +P S+ T K P
Sbjct: 385 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP------- 437
Query: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESK----G 842
T P K P + P T ++ +P K PA +K P P++ +
Sbjct: 438 -----TTPKKPAPTTPKEPAPTTPKEPTPTTPK---EPAPTTK---EPAPTTPKEPAPTA 486
Query: 843 QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902
K+ P KE + +P +P P TP P PT ++ PT + P P
Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT---TPKEPAPTTTKSAPTTTKEPAPT--- 540
Query: 903 RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGA 962
KS PTTP+E S + +T +P P + P
Sbjct: 541 ------------TTKSAPTTPKEP----------SPTTTKEPAPTTPKEPAPTTPKKPAP 578
Query: 963 PMKQAPAPSQP----PTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ--AP 1016
+ PAP+ P PT+ P T PAP KET +KL P + AP
Sbjct: 579 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT----TPKETAPTTPKKLTPTTPEKLAP 634
Query: 1017 TVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPK-PESTCPLCKTELNIGSKDPPN 1075
T T +KP P + P++ T E +P P++ P E + P
Sbjct: 635 T-----TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 689
Query: 1076 FNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKAS 1135
T E P P + +T PAP+ PK
Sbjct: 690 PTTPKE------------PAPTTPK---------ETAPTTPKGTAPTTLKEPAPTTPKK- 727
Query: 1136 PMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQ 1195
P P E + T P K K A E T P TT +
Sbjct: 728 --PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK----EPAPTTPKGT 781
Query: 1196 EESKLEKDKASALQEKKPLPEE-----------------KKLIPEEEKIRSEEKKPLLEE 1238
+ L++ + KKP P+E P+E + ++
Sbjct: 782 APTTLKEPAPTT--PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 839
Query: 1239 KKPTPEDKKLLP----EAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEG-KQPQT 1293
KKP P + P E T ++ + KS + E L PK ++ K+P
Sbjct: 840 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE-LSAEPTPKALENSPKEPGV 898
Query: 1294 KMEGLPSGT-PQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQ 1352
P+ T P+ DKTT+ TA P + TEK + T+++
Sbjct: 899 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 958
Query: 1353 QPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL 1412
Q S T + + ++ + + T +K I + ++ + P D A
Sbjct: 959 QVTSTTTQDTTPFKITTLKTT--TLAPKVTTTKKTI---TTTEIMNKPEETAKPKDRA-- 1011
Query: 1413 ESTVLSILEAQASTLADEK----SEKKTQPHEVSPE-QPKDQEKTQSLSETLEITISEEE 1467
++ + + Q T A +K + KT P P+ P ++ T ++ E + E
Sbjct: 1012 TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1071
Query: 1468 IKESQEERKDTFKKDSQQDIPSSKD 1492
+ ++ T + P S+D
Sbjct: 1072 MLQTTTRPNQTPNSKLVEVNPKSED 1096
Score = 92.0 bits (227), Expect = 1e-17
Identities = 203/952 (21%), Positives = 313/952 (32%), Gaps = 140/952 (14%)
Query: 2078 PGSSPTQAPIGEDMT--ESTMDFDRMPDASLTSSVLSGASLTD--STSSATLSIPDVKIT 2133
P S P G T +T + P+ T V+ +T+ S S S +
Sbjct: 114 PSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSS 173
Query: 2134 QHFST-EEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSS-- 2190
ST +I+ + RE+Q+ L + ++ T P+ P + S
Sbjct: 174 SSSSTIRKIKSSKNSAANRELQKK-------LKVKDNKKNRTKKKPTPKPPVVDEAGSGL 226
Query: 2191 ------VCTTDSSSP----ITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYP 2240
V T D+S+ ++T ITT +P++ + + S T +
Sbjct: 227 DNGDFKVTTPDTSTTQHNKVSTSPKITTA--KPINPRPSLPPNSDTSKETS-----LTVN 279
Query: 2241 EEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDP 2300
+E +V T + + S D + S + IE K P + ++ P
Sbjct: 280 KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK--------P 331
Query: 2301 VKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPM--KEQLST 2358
KA+ T A KE K S T + P+++ + P KE T
Sbjct: 332 TPKAETTTKG-------PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 384
Query: 2359 TYFTSGETFGQEKPASQLPSGSPSVSSLPA-----KPRPFFRSSSLDISAQPPPPPPPPP 2413
T S T +E + +P+ PA +P P S+ +P P P P
Sbjct: 385 TT-KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443
Query: 2414 ----PPPPPP----------------------------PPPPPPPLPPPTSPK---PTIL 2438
P P P P P P P PT+PK PT
Sbjct: 444 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 503
Query: 2439 PKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLV 2498
+ T + TP A TT ++ P T T + P P +PS +
Sbjct: 504 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT---TKSAPTTPKEPSPTTTKEP 560
Query: 2499 FTHRPE------PSKP----PIAPKPVIPQ--LPTTTQKPTDIHPK---PTGLSLTSSMT 2543
P+ P KP P P P P+ PTTT+KP PK PT T+ T
Sbjct: 561 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 620
Query: 2544 LNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITS 2603
+T + +PT+P P ++P T T P EP T +A+
Sbjct: 621 PKKLTPTTPEKLAPTTPEKP--APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK 678
Query: 2604 WPLGSPSKDLVSVEP--VFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQA 2661
P + K+ P P TA P + T L+ + T P+ +
Sbjct: 679 EPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPT-----TLKEPAPTTPKKPAPKEL 733
Query: 2662 APTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKL 2721
APT+ + +T K + + TAP+ + T P EP P+ L
Sbjct: 734 APTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPAPTTPKEPAP------TTPKGTAPTTL 786
Query: 2722 QLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVT 2781
+ + PK TT K +++T D T E P+
Sbjct: 787 KEPAPTTPKKPAPKELAPTTTK--GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844
Query: 2782 SSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAMTTPLQLTTS--KHAEPPYRIP 2839
++ TP +E T T + + A TP L S + P + P
Sbjct: 845 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTP 904
Query: 2840 S-----------DQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVTNGWTDSTV 2888
+ D+ P + T T+ T + T ST
Sbjct: 905 AATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTT 964
Query: 2889 SQGITDGEVVDLSTTKSHRTVVTMDE--STSSVMTKIIEDEKPVDLTAGRRA 2938
+Q T ++ L TT V T + +T+ +M K E KP D +A
Sbjct: 965 TQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 1016
Score = 70.1 bits (170), Expect = 5e-11
Identities = 113/523 (21%), Positives = 162/523 (30%), Gaps = 88/523 (16%)
Query: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPST 132
P E P+ +EL + P + + P+ P P K+ +T + + P+
Sbjct: 634 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAPNTPKEPAPTTPKEPAP 690
Query: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192
+ KE TT K
Sbjct: 691 TTPKE------------------------------------------------PAPTTPK 702
Query: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252
+ +G +K P P KP PK+ P ++ T + P K P
Sbjct: 703 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP---TTTKEPTSTTCDKPAPTTPKGTAP 759
Query: 253 GTGK---PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
T K P P T P P T + + E + P+ +P
Sbjct: 760 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK-ELAPTTTKGPTSTTSDKP 818
Query: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPA 369
P P P K +P P P KP P T P T +P
Sbjct: 819 APTTPKETAPTTPK-EPAPTTP-------KKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 870
Query: 370 KPPAQQTGSEKPSSEQPGPKAL---AQPPGV--GKTPAQQPGPAKPPTQQVGTPKPLAQQ 424
K P + T S +P PKAL + PGV KTPA + T + L
Sbjct: 871 KSPDEST---PELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTT 927
Query: 425 PGLQSPA-KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483
P + A K T T ++ KI A T+ Q T P K + P
Sbjct: 928 PETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT 987
Query: 484 PGPA------KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSA 537
P++ K + +T P PQ+P A P++P STK P P
Sbjct: 988 TKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKA---PKKPTSTKKPKTMPRVR 1044
Query: 538 KPSAQQPSPAK-PSAQQSTKPVSQTGSG--KPLQPPTVSPSAK 577
KP P+P K S P S+ + P +P++K
Sbjct: 1045 KPKT-TPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 1086
Score = 60.8 bits (146), Expect = 3e-08
Identities = 107/491 (21%), Positives = 169/491 (34%), Gaps = 56/491 (11%)
Query: 2165 TYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITK--FED 2222
T EPS + T P TP + T +P T + T EP TK
Sbjct: 548 TPKEPSPTTTKEPAPTTPKEPAPT----TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 603
Query: 2223 SEEISSSTYFPGSIIDYPEEISVSL-DRTAPPDGRASADHIVISLSDMASSIIESVVPK- 2280
+ + + T + P++++ + ++ AP A + ++A + E P
Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP---TTPEELAPTTPEEPTPTT 660
Query: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF 2340
PE P T + K+P KE E A KE A T + T
Sbjct: 661 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKET-APTTPKGTAPTTL 717
Query: 2341 DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
P + P ++L+ T + +KPA P G+ + P +P P
Sbjct: 718 KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT--PKEPAPTTPKEPAP 775
Query: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA-------- 2452
+ + P P P P P P L P T+ PT K +P TA
Sbjct: 776 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA 835
Query: 2453 --TPLFDAVTTLETTAVLRSN-GLPVTRICTT----APPPVPPKPSSIPSGLVFTHRP-E 2504
TP A TT ET S P T T +P P+ S+ P+ + P E
Sbjct: 836 PTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE 895
Query: 2505 PSKPPI-APKPVIPQLPTTTQKPT---DIHPKPTGLSLTSSMTLNLVTSADY----KLPS 2556
P P P P++ TT + T D+ P + MT T+ + K+ +
Sbjct: 896 PGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITA 955
Query: 2557 PTSPLSPHSNKSSPRF----------------SKSLTETYVVITLPSEPGTPTDSSASQA 2600
T+ ++ + + + F +K T ++ P E P D + +
Sbjct: 956 TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSK 1015
Query: 2601 ITSWPLGSPSK 2611
T+ P+K
Sbjct: 1016 ATTPKPQKPTK 1026
Score = 58.9 bits (141), Expect = 1e-07
Identities = 106/470 (22%), Positives = 154/470 (32%), Gaps = 74/470 (15%)
Query: 2169 PSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISS 2228
P E A + P P+ T + T ++P T + T EP K +E++
Sbjct: 677 PKEPAPTTPKEPAPT-TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735
Query: 2229 STYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADT 2288
+T E S + D+ AP + +A PK P
Sbjct: 736 TTT--------KEPTSTTCDKPAPTTPKGTAP----------------TTPKEPAPT--- 768
Query: 2289 VSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDK---KELEAERTKSSLSETVFDHP-- 2343
+ K+P K T + E K KEL TK S T D P
Sbjct: 769 -------TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS-TTSDKPAP 820
Query: 2344 --PSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDI 2401
P KE TT T + P + +P+ + P S+ ++
Sbjct: 821 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880
Query: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-----VASPVTTATPLF 2456
SA+P P P P P P T P+ T K K T TTA P
Sbjct: 881 SAEPTPKALENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKM 937
Query: 2457 --DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
+ TT E T + TT P K +++ + +APK
Sbjct: 938 TKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT------------TTLAPKV 985
Query: 2515 VIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNL-VTSADYKLPS--PTSPLSPHSNKSSPR 2571
+ TT T+I KP + N T+ + P+ P P S K+ PR
Sbjct: 986 TTTKKTITT---TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 1042
Query: 2572 FSK---SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEP 2618
K + T + T+P T + A T+ P +P+ LV V P
Sbjct: 1043 VRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNP 1092
Score = 57.4 bits (137), Expect = 4e-07
Identities = 111/597 (18%), Positives = 196/597 (32%), Gaps = 34/597 (5%)
Query: 947 STAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAE 1006
+T P P ++ ++ + S+ S+ + + + +I K +K AA
Sbjct: 132 TTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAAN 191
Query: 1007 KLEPKAEQAPTVKRTETEKKP---PPIKDS--KSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
+ K + K+ T+KKP PP+ D L K P ST P
Sbjct: 192 RELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK 251
Query: 1062 CKTELNIGSKD--PPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQL 1119
T I + PPN +T E V N T T + + + + + +
Sbjct: 252 ITTAKPINPRPSLPPNSDTSKETSLTV-NKETTVETKETTTTNKQTSTDGKEKTTSAKET 310
Query: 1120 GDIRKMPPAPSGPKASPMPVPTESSSQKTAVP----PQVKLVKKQEQEVKTEAEKVILEK 1175
I K P + + PT + T P P+ ++ T ++
Sbjct: 311 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 370
Query: 1176 VKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPL 1235
+K + K P TT K + + K+P P K E ++E P
Sbjct: 371 IKSAPTTPKEPAPTTTKSAPTTPK----EPAPTTTKEPAPTTPK---EPAPTTTKEPAPT 423
Query: 1236 LEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKM 1295
+ PT + K AP K + + + AP T + P T
Sbjct: 424 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK-EPAPTTKEPA--PTTPK 480
Query: 1296 EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355
E P+ + P + T ++P P T +P P ++ KS +++++P
Sbjct: 481 EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP--KEPAPTTTKSAPTTTKEPA 538
Query: 1356 SPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLEST 1415
S + ++ E P + + +E +P++P + A
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP---- 594
Query: 1416 VLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEER 1475
+ + A T E + T P E +P PK + T + E L T E+ + EE
Sbjct: 595 --TTTKKPAPTTPKEPA--PTTPKETAPTTPK--KLTPTTPEKLAPTTPEKPAPTTPEEL 648
Query: 1476 KDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTS 1532
T ++ P + P E + + P P + T+
Sbjct: 649 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 705
Score = 46.6 bits (109), Expect = 6e-04
Identities = 65/287 (22%), Positives = 105/287 (36%), Gaps = 17/287 (5%)
Query: 3464 TKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTKPLSKVSSIAVQTVAE 3523
TK++ T+ QT + +++ T S ++ + + + A +K L+K + A T
Sbjct: 286 TKETTTTNKQTSTDGKEK----TTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 341
Query: 3524 ISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSA 3583
++ T T TP A K I + T K + A + + P +
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 401
Query: 3584 TSP-PKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLY----SPISPLSPGKALES 3638
P P K P P ++ A +T + AP+ PK P +P +P P
Sbjct: 402 KEPAPTTPKEPAPT----TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 457
Query: 3639 AFVPY--EKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSP-TADESSRA 3695
P ++P P P + A P P + + + PK +P T E S
Sbjct: 458 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 517
Query: 3696 PFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFST 3742
+ TTK + T T A K + P P E T T+ T
Sbjct: 518 TPKEPAPTTTKSAPTTTKEPAPTTTK-SAPTTPKEPSPTTTKEPAPT 563
Score = 40.8 bits (94), Expect = 0.035
Identities = 92/432 (21%), Positives = 151/432 (34%), Gaps = 68/432 (15%)
Query: 2165 TYSEPSESATSVP-PSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFE-- 2221
T EP+ + P P + T+ + T+D +P T ++ T EP K
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844
Query: 2222 --------DSEEISS--STYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMAS 2271
+ E+S+ +T P +I P+E + L +A P +A + +
Sbjct: 845 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL--SAEPTPKA-----------LEN 891
Query: 2272 SIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERT 2331
S E VP + P A ++ + KD + T + ++ + T
Sbjct: 892 SPKEPGVPTTKTPAA--TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 949
Query: 2332 KSSL--------SETVFDHPPSSVIALP---MKEQLSTTYFTSGETFGQEKPASQLPSGS 2380
+S + S T D P + L + +++TT T T KP
Sbjct: 950 ESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET----- 1004
Query: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPK 2440
AKP+ +S A P P P P P P +P PK T P+
Sbjct: 1005 -------AKPKDRATNSK----ATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1053
Query: 2441 KKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP--PPVPPKPSSIPSGLV 2498
K + + + + +A+ L+TT R N P +++ P P L+
Sbjct: 1054 KMTSTMPELNPTSRIAEAM--LQTTT--RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1109
Query: 2499 FTH------RPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPT-GLSLTSSMTLNLVTSAD 2551
H P+ P P I P + + + KP GL+ + TL
Sbjct: 1110 RPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTLRNGTLVAFRGHY 1169
Query: 2552 YKLPSPTSPLSP 2563
+ + SP SP SP
Sbjct: 1170 FWMLSPFSPPSP 1181
Score = 39.3 bits (90), Expect = 0.10
Identities = 89/413 (21%), Positives = 145/413 (35%), Gaps = 63/413 (15%)
Query: 3582 SATSPPKDKKRPTPLEIGYSSHLRADSTV--QLAPSPPK--SPKVLYSPISPLSPGKALE 3637
+A + PK+ TP E ++ T + AP+ PK +P L P +P +P
Sbjct: 672 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP-APTTP----- 725
Query: 3638 SAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAK-MMQRSMSDPKPLSP--------- 3687
+KP P +++P P +P T K + +P P +P
Sbjct: 726 ------KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 779
Query: 3688 -TADESSRAPFQYT---------EGYTTKGSQTMTS-SGAQKKVKRTLPNPPPEEISTGT 3736
TA + + P T TTKG + TS A K T P P E T
Sbjct: 780 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 839
Query: 3737 QSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDA 3796
+ T +T K I + D + EL E
Sbjct: 840 KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD----------ESTPELSAEPTPKAL 889
Query: 3797 KLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERP 3856
+ E G+ K + E A + +RD + E ++ P + E
Sbjct: 890 ENSPKEPGVPTTKTPAATKPEMTTTA--KDKTTERDLRTTPETTTAAPKMTK-----ETA 942
Query: 3857 RTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYH 3916
T +T S+ TQ S T+P ++ ++ T AP T + + +
Sbjct: 943 TTTEKTTESKITATTTQVTSTTTQDTTP---FKITTLKTTTLAPKVTTTKKTITTTEIMN 999
Query: 3917 QQVSPYQT-QPTFQAVATMSFTPQVQ-PTPTP-QPSYQLPSQMMVIQQKPRQT 3966
+ P +T +P +A + + TP+ Q PT P +P+ + M +KP+ T
Sbjct: 1000 K---PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTT 1049
Score = 34.7 bits (78), Expect = 2.5
Identities = 37/154 (24%), Positives = 52/154 (33%), Gaps = 20/154 (12%)
Query: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKAL-ESAFV 3641
A + PK TP E AP+ PK P +P +P P E A
Sbjct: 436 APTTPKKPAPTTPKE--------------PAPTTPKEP----TPTTPKEPAPTTKEPAPT 477
Query: 3642 PYEKPLPD-DISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYT 3700
++P P P + A P P + S + PK +PT +S+ +
Sbjct: 478 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 537
Query: 3701 EGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEIST 3734
TTK + T + K P P E T
Sbjct: 538 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 571
Score = 32.7 bits (73), Expect = 9.6
Identities = 39/168 (23%), Positives = 66/168 (39%), Gaps = 8/168 (4%)
Query: 3583 ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVP 3642
A + PK+ TP E ++ + T P+P + + L+P + A
Sbjct: 577 APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT 636
Query: 3643 YEKP---LPDDISPQKVLHPDMAKVPPASPKTAK-MMQRSMSDPKPLSP--TADESSRAP 3696
EKP P++++P P +P T K + +P P +P A + + P
Sbjct: 637 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 696
Query: 3697 FQYTEGYTTKGSQTMTSSGAQKKVKRTLP-NPPPEEIS-TGTQSTFST 3742
T T + T+ K+ T P P P+E++ T T+ ST
Sbjct: 697 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST 744
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 158 bits (399), Expect = 2e-37
Identities = 242/997 (24%), Positives = 371/997 (37%), Gaps = 173/997 (17%)
Query: 166 VSSVVNKFNPF-DLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQG 224
+ SV + P S E T + + QG+P+G +Q + P P+ +
Sbjct: 358 IRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAK 417
Query: 225 P-GRDPLQQDGTPKSISSQQ------PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRD 277
P G+ +Q + ++ +++ PE+ PP P P P+ P +
Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP---PEASRLSPPPEEL 474
Query: 278 ASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQP----------GHEKSQPG 327
+ P + + R P SP PP ++ PP P E+S P
Sbjct: 475 PASPLPEALHLSR-----PLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPS 529
Query: 328 PA-----KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS 382
PA PP + S L+ P + P PP + P + P A L P PP E P
Sbjct: 530 PALETPLSPPPEASPLSPPFEESP-LSPPPEELPTSPPPEASRLSP--PP-----EESPM 581
Query: 383 SEQPGPKALAQPPGVGKT-PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
S P ++ PP + P + P PP ++ PL+ P ++ +P P +P+
Sbjct: 582 SPPPEESPMSPPPEASRLFPPFEESPLSPPPEE----SPLSPPP--EASRLSPPPEDSPM 635
Query: 442 QQPGPGKIPAQQAGPGKTSAQQTGPT----KPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
P P + P + P + S P PP + P PPP++ P PPP+ +
Sbjct: 636 SPP-PEESP--MSPPPEVSRLSPLPVVSRLSPPPE-ESPLSPPPEE-SPTSPPPEASRLS 690
Query: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
PP P T PPP+ PA P P+ + P + P P Q P S +P
Sbjct: 691 PPPEDSP--TSPPPED-SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747
Query: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617
S +P + P +SP A++P P+ C L VPE+ + + E
Sbjct: 748 EEPHLSPRP-EEPHLSPQAEEPHLSPQPEEPC--------LCAVPEEPHLSPQAE----- 793
Query: 618 CSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLKTAPVTTTSAVSKS 675
PHL+ E L L+ Q + L+PVP P P+ + + ++ S
Sbjct: 794 --------GPHLSPQPEELHLSPQTEEP---HLSPVPEEPCLSPQPEESHLSPQSEEPCL 842
Query: 676 SPQPQQT--SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
SP+P+++ SP+ + P +P P+KPP + Q P + L
Sbjct: 843 SPRPEESHLSPELEKPP-----LSPRPEKPP-------------EEPGQCPAPEELPLFP 884
Query: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
PP EPS+ + +++ P +P + +L S S PS Q + P
Sbjct: 885 PPGEPSLSPLLGEPALSE--PGEPPLSPLPEELPLSPSGE-----PSLSPQLMPPDPLPP 937
Query: 794 PLK---TDSAKPSQSFPPTGEKVSPFDSKAIPRPASD--SKIIS---HPGPSSESKGQKQ 845
PL T +A P+ S P GE PF +K P S + I+ P P + +
Sbjct: 938 PLSPIITAAAPPALS--PLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEP 995
Query: 846 VDPVQKKEEPKKAQTKMSP------KPDAKPM------PKGSPTPPGPRPTAGQTVPTPQ 893
V P+ P SP P P+ P+ SP P +VP+P
Sbjct: 996 VPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSP- 1054
Query: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
SP + L + S+P P + + + S +L A P
Sbjct: 1055 LSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT-----SPLPSPMGDLSCPAPSPA 1109
Query: 954 PHSQSGPG-----APMKQAPAP-SQPPTSQGPPKSTGQ-------------APPAPAKSI 994
P G AP+ AP SQP Q P + AP P +
Sbjct: 1110 PALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVY 1169
Query: 995 PVKKETK---APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLP--TKL 1049
P K+T +P E+ EP+A APT T K + + +L+ A P L
Sbjct: 1170 PECKQTAGQGSPCEEQEEPRAPVAPT---PPTLIKSDIVNEISNLSQGDASASFPGSEPL 1226
Query: 1050 EKSPKPESTCPLCKTELNIG-----SKDPPNFNTCTE 1081
SP PE L EL + ++D + CT+
Sbjct: 1227 LGSPDPEGGGSL-SMELGVSTDVSPARDEGSLRLCTD 1262
Score = 114 bits (284), Expect = 3e-24
Identities = 224/1110 (20%), Positives = 362/1110 (32%), Gaps = 197/1110 (17%)
Query: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGR-PAQPGLSKSRTTDTFRSEQKLPGRSPS 131
P ESP +E +S PP+ S P P PA P P
Sbjct: 442 PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASP--------------------LPE 481
Query: 132 TISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTK 191
+ L + L + S + S + +PF + +S S E +
Sbjct: 482 ALHLSRPLEESPLSPPPEESPL--------------SPPPESSPFSPLEESPLSPPEESP 527
Query: 192 KQKVVQKEQGKP--EGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKS 249
++ P + PP ++ P P P++ P S S PE+
Sbjct: 528 PSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP------EASRLSPPPEESPM 581
Query: 250 QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
PP P+ P P+ P + P +++ + P P P+ P
Sbjct: 582 SPPPEESPMSPP---PEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP 638
Query: 310 TPGKPPAQQPGHEKSQPGPA----KPPAQPSGLTKPLAQQP-------GTVKPPVQPPGT 358
P + P + P P PP + S L+ P + P + PP + T
Sbjct: 639 PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT 698
Query: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418
+ PP PA PP + + P E P L P + + GP P +
Sbjct: 699 SPPPED--SPASPPPEDSLMSLPLEESP----LLPLPEEPQLCPRSEGPHLSPRPEEPHL 752
Query: 419 KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAK 478
P ++P L A+ P + P ++P +P + + P L +
Sbjct: 753 SPRPEEPHLSPQAEEPHLSPQP-EEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTE 811
Query: 479 PPPQQPGPAKP---PPQQPGSAKPPSQQPG-STKP-----------PPQQPGPAKPSPQQ 523
P P P +P P + P S++P S +P PP P P KP P++
Sbjct: 812 EPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP-PEE 870
Query: 524 PGSTKPPSQQPGSAKPSAQQPSP--AKPS-AQQSTKPVSQTGSGKPLQP---PTVSPSAK 577
PG P + P P SP +P+ ++ P+S PL P P++SP
Sbjct: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
Query: 578 QPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLC 637
P LP + P+ P L+ + E
Sbjct: 931 --PPDPLPPPLSPIITAA-----------------------------APPALSPLGE--- 956
Query: 638 LNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP-----QQTSPKKDAAPKQ 692
+ GD P P L+T P++ + + P+P SP P
Sbjct: 957 --LEYPFGAKGDSDPESPLAAPILET-PISPPPEANCTDPEPVPPMILPPSPGSPVGPAS 1013
Query: 693 DLSKAPEPKKPPPLVKQPTL-HGSPSAKAKQPPEADSLSKPAPP--KEPSVPSEQDKAPV 749
+ P P + PL++ + SP ++ P S+ P P K V E + +
Sbjct: 1014 PILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEM 1073
Query: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPT 809
+K +P + + + T P +PS + P D F
Sbjct: 1074 ETEKVSEP-------ECPALEPSATSP-LPSPMGDLSCPAPSPAPALDD-------FSGL 1118
Query: 810 GEKVSPFDSKAIPRPASDSKIISHPGP-SSESKGQ---------KQVDPVQKKEEPKKAQ 859
GE +P D I P S + PG +SE KG V P++ E K+
Sbjct: 1119 GEDTAPLD--GIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTA 1176
Query: 860 TKMSP-KPDAKPMPKGSPTPPG-------------PRPTAGQTVPTPQQ---SPKPQEQS 902
+ SP + +P +PTPP + A + P + SP P E
Sbjct: 1177 GQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDP-EGG 1235
Query: 903 RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS---TAGQPGPHSQSG 959
S+ LG TD ++ T L S+ A IS G+ G S
Sbjct: 1236 GSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSP 1295
Query: 960 PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019
+ +KQ + S P G + G A + +L+ A T+
Sbjct: 1296 ARSRIKQGRSSSFP----GRRRPRGGAHGG-----------RGRGRARLKSTASSIETLV 1340
Query: 1020 RTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTC 1079
+ + P ++ + VL + +K + C +C + G + C
Sbjct: 1341 VADIDSSPSKEEEEEDDDTMQNTVVLFSNTDKFVLMQDMCVVCG---SFGRGAEGHLLAC 1397
Query: 1080 TECKNQVCNLCGFNPTPHLTEIQEWLCLNC 1109
++C C + + ++ W C+ C
Sbjct: 1398 SQCSQCYHPYCVNSKITKVMLLKGWRCVEC 1427
Score = 104 bits (259), Expect = 3e-21
Identities = 186/786 (23%), Positives = 263/786 (33%), Gaps = 134/786 (17%)
Query: 46 SQLSEEERRQIAAVMSRAQGLPKGSVP--PAAAESPSMHRKQELDSSHPPKQSG------ 97
S LS E + + P + P P ESP +EL +S PP+ S
Sbjct: 518 SPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
Query: 98 ----RPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMM 153
PP P P SR F P S +S SR E
Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637
Query: 154 PGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ 213
P S ++ VS + +P ++S EE+ + PP ++
Sbjct: 638 PPEESPMSPPPEVS----RLSPLPVVSRLSPPPEESP----------------LSPPPEE 677
Query: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLP 273
P P P+ S S PE + PP P P P+ LP
Sbjct: 678 SPTSPPPE---------------ASRLSPPPEDSPTSPPPEDSPASPP---PEDSLMSLP 719
Query: 274 LQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP---PAQQPGHEKSQPG--- 327
L+ P ++ + P P +P + P P +P P + H QP
Sbjct: 720 LEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL-SPRPEEPHLSPQAEEPHLSPQPEEPC 778
Query: 328 ----PAKPPAQPSGLTKPLAQQPGT--VKPPVQPPGTTKPPAQP-LGPAKPPAQQTGSEK 380
P +P P L+ QP + P + P + P +P L P + + +
Sbjct: 779 LCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE 838
Query: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ--QVGTPKPLAQQPGLQSPAKAPGPTK 438
P P+ P + K P P P KPP + Q P+ L P P+ +P +
Sbjct: 839 EPCLSPRPEESHLSPELEKPPL-SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897
Query: 439 TPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP--GPAKPPPQQP- 494
+ +PG P P + P S + P+ P +P PPP P A PP P
Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGE---PSLSPQLMPPDPLPPPLSPIITAAAPPALSPL 954
Query: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSPQQP----GSTKPPSQQPGSAKPSAQQP-SPAKP 549
G + P G + P P +P P T P P PS P PA P
Sbjct: 955 GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASP 1014
Query: 550 SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL--PKTICPLCN----TTELLLHVPE 603
+ P L P PS PP+ L P + P+ + E LH E
Sbjct: 1015 ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEME 1074
Query: 604 KANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL-- 661
+ EC S P+P GDL+ SP P L
Sbjct: 1075 TEKVSE-PECPALEPSATSPLPSPM-------------------GDLSCPAPSPAPALDD 1114
Query: 662 ------KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715
TAP+ A S P+P QT S A E K P L+ L +
Sbjct: 1115 FSGLGEDTAPLDGIDAPG-SQPEPGQTPG----------SLASELKGSPVLLDPEEL--A 1161
Query: 716 PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK 775
P + PE + P E E+ +APVA P P ++K +D+V+ S ++
Sbjct: 1162 PVTPMEVYPECKQTAGQGSPCE---EQEEPRAPVA---PTPPTLIK--SDIVNEISNLSQ 1213
Query: 776 PDIPSS 781
D +S
Sbjct: 1214 GDASAS 1219
Score = 92.4 bits (228), Expect = 1e-17
Identities = 178/816 (21%), Positives = 269/816 (32%), Gaps = 181/816 (22%)
Query: 541 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH 600
AQ + A+Q T S+ +P PT P A QG PK
Sbjct: 352 AQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPK-------------- 397
Query: 601 VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPK 660
V S+ P P L C+ K + P P
Sbjct: 398 -------------GGHVTSMQPKEPGP----------LQCEAKPLGKAGVQLEPQLEAPL 434
Query: 661 LKTAPVTTTSAVSKSSPQPQQ--TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
+ P+ S SP P++ TSP +A+ LS PE PL + L
Sbjct: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEAS---RLSPPPEELPASPLPEALHLSRPLEE 491
Query: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
PP +S P P P P E+ ++ P P + P + +S + P
Sbjct: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLS--PPF 549
Query: 779 PSSKVQSQAEE-KTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPS 837
S + EE T+PP + P PP +SP ++ P ++ + P
Sbjct: 550 EESPLSPPPEELPTSPPPEASRLSP----PPEESPMSPPPEESPMSPPPEASRLFPPFEE 605
Query: 838 SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPM-PKGSPTPPGPRPTAGQTVPTP---Q 893
S + P+ P +++SP P+ PM P +P P P + P P +
Sbjct: 606 SPLSPPPEESPL----SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSR 661
Query: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
SP P+E ++ P+ PT+P
Sbjct: 662 LSPPPEE---------SPLSPPPEESPTSP------------------------------ 682
Query: 954 PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA-KSIPVKKETKAPAAE--KLEP 1010
P + +P P PTS P S PP + S+P+++ P E +L P
Sbjct: 683 ------PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736
Query: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS 1070
++E P + E P + L+ + ++ L SP+PE C LC
Sbjct: 737 RSE-GPHLSPRPEEPHLSPRPEEPHLSPQAEEPHL------SPQPEEPC-LCAV------ 782
Query: 1071 KDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPS 1130
+ P+ + E PHL+ E L L+ QT+ + P P
Sbjct: 783 PEEPHLSPQAE-------------GPHLSPQPEELHLSPQTEEP---------HLSPVPE 820
Query: 1131 GPKASPMPVPTESS--SQKTAVPPQVKLVKKQEQEVKTEAEKVIL--------EKVKETL 1180
P SP P + S S++ + P + +E + E EK L E+ +
Sbjct: 821 EPCLSPQPEESHLSPQSEEPCLSP-----RPEESHLSPELEKPPLSPRPEKPPEEPGQCP 875
Query: 1181 SMEKIPPMVTTDQKQEESKLEKDKASALQEK--KPLPEEKKLIPEEEKIRSEEKKPLLEE 1238
+ E++P + L + S E PLPEE L P E S + P
Sbjct: 876 APEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMP---- 931
Query: 1239 KKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGL 1298
P P L P +AP A L P + P++ +
Sbjct: 932 --PDPLPPPLSPIITAAAPP-------------ALSPLGELEYPFGAKGDSDPESPLAAP 976
Query: 1299 PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334
TP S P E + T +P PP P P
Sbjct: 977 ILETPISPPPEANCT----DPEPVPPMILPPSPGSP 1008
Score = 85.9 bits (211), Expect = 1e-15
Identities = 251/1123 (22%), Positives = 366/1123 (32%), Gaps = 204/1123 (18%)
Query: 65 GLPKGSVPPAAAES--PSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSE 122
GLP G++P ++ P + + LDS + P+PG P P TT + +
Sbjct: 1929 GLPLGNLPSSSPMDSYPGLCQSPFLDSRE--RGGFFSPEPGEPDSPWTGSGGTTPSTPTT 1986
Query: 123 QKLPGRSPSTISLKESKSRTDLKEE--HKSSMMPGFLSEVNA----------LSAVSSVV 170
G + S R + EE S++ P + +N S ++
Sbjct: 1987 PTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSSRCKQIM 2046
Query: 171 NKFN--------PFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKP---- 218
+ P+ + + K QK + + K + + ++ +P
Sbjct: 2047 KLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKV--GDIARKTDRPALHL 2104
Query: 219 -IPKQQGP-GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD---HAKLP 273
IP Q G G P T S P + + G KP G P + KLP
Sbjct: 2105 RIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP 2164
Query: 274 LQRDASRPQTKQADIVRGESVKPSLPS--PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP 331
Q A P + ++P P+ P+ PP PT PA+P
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGA---------------PAQP 2209
Query: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL 391
P + ++P A QPG PPGT P P+ KP A+
Sbjct: 2210 PMLGAS-SRPGAGQPGEFH--TTPPGT---------PRHQPSTPDPFLKPRCPSLDNLAV 2257
Query: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP-GLQSPAKAPGPTKTPVQQPGPG--- 447
+ PGVG A +P + PP + + ++ G SP+ P P V P G
Sbjct: 2258 PESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGP-PNLGFVDSPSSGTHL 2316
Query: 448 -----KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
K P P A Q P P L PQ+P PA+ P S P
Sbjct: 2317 GGLELKTPDVFKAPLTPRASQVEPQSPGLGLR------PQEPPPAQALAPSPPS-HPDIF 2369
Query: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
+PGS P QP P P PQ PP + A P PS P ++ P SQ+
Sbjct: 2370 RPGSYTDPYAQP-PLTPRPQ------PPPPESCCALPPRSLPS--DPFSRVPASPQSQSS 2420
Query: 563 SGKPLQPPTVSPSA----------------KQPPSQGLPKTICPLCNTTELLLHVPEKAN 606
S PL P +S A +PPS+ P++ P + P +
Sbjct: 2421 SQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR--PQSRDPFAPLHKPPRPQPPEVA 2478
Query: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDL-APVPSSPQPKLKTAP 665
F + T++ GF + G+L A VPS P +P
Sbjct: 2479 FKAGSLAHTSL-GAGGF---------------PAALPAGPAGELHAKVPSGQPPNFVRSP 2522
Query: 666 VTTTSAVSKSSPQPQQ-TSPKKDAAPKQDLSKAPEPKKPPP------LVKQPTL------ 712
T +P P + T P+ P P+P PPP PTL
Sbjct: 2523 GT---GAFVGTPSPMRFTFPQAVGEPSLK-PPVPQPGLPPPHGINSHFGPGPTLGKPQST 2578
Query: 713 -----------HGSP-SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ---- 756
GSP + E+ LS PP P+ P Q
Sbjct: 2579 NYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGI 2638
Query: 757 ----PKMVKPTTDLVSSSSATTKPDI--PSSKVQSQAE-EKTTPPLKTDSAKPSQSFPPT 809
K P T + SS + P P SQ E EK + Q
Sbjct: 2639 TSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRN 2698
Query: 810 ----GEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEE-----PKK--- 857
++ + + A+ P S S P S+GQ Q K P K
Sbjct: 2699 TLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSG 2758
Query: 858 ---------AQTKMS-PKPDAKP--MPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRF 905
+ ++S P P A P M S G Q P P P Q+Q + +
Sbjct: 2759 PILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLW 2818
Query: 906 SLNLGSITDAPKSQ-----PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
+ + + P+TP + + G S + S + G+P P GP
Sbjct: 2819 QQQQATAATSMRFAMSARFPSTPGPELGRQALG---SPLAGISTRLPGPGEPVP----GP 2871
Query: 961 GAPMKQAPAPSQPPTSQGPPKS--TGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
P + GP + GQ PP + PV ++ A E L A
Sbjct: 2872 AGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPP 2931
Query: 1019 KRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
++ + P + +S T + LPT LE +P S+ L
Sbjct: 2932 QK-PSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTEL 2973
Score = 84.7 bits (208), Expect = 2e-15
Identities = 188/829 (22%), Positives = 280/829 (33%), Gaps = 146/829 (17%)
Query: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQ---GPGRD--PLQQDGTPK 237
+ Q++ ++Q+ Q++Q + G++ P+ +QQ GPG PLQ +P
Sbjct: 3954 QLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPG 4013
Query: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297
++ K Q T+ P T H PL T ++ VKPS
Sbjct: 4014 ALGPTLLLTGKEQNTVDPAVSSEATEGPST-HQGGPLAIGT----TPESMATEPGEVKPS 4068
Query: 298 LPSPSKPPIQQPTPG--------KPPAQQPGHEKSQ------PGPAKPPAQPSGLTKPLA 343
L S+ + QP P +PP + PG ++ Q G SG + +
Sbjct: 4069 LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEAS 4128
Query: 344 QQPGTVKPPV-----QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP---- 394
P + P QP T+ LGP +P ++ + P P + Q
Sbjct: 4129 SVPHLLAQPSVSLGDQPGSMTQ---NLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGL 4185
Query: 395 PGVGKTP------AQQPGPAKP--------PTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440
PGVG P AQ G P QQ L Q+ QS A P P
Sbjct: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTP---P 4242
Query: 441 VQQPGPGKIPAQ-----QAGPGKTSAQQTGPTKPPSQLPGPAKPP--PQQPGPAKPPPQQ 493
Q+PG P Q Q G QTGP + P P PP P PG P
Sbjct: 4243 YQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVL 4302
Query: 494 -PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ--QPSPAK-- 548
P PP P K P Q P P S Q P + P PG+ KP +P P +
Sbjct: 4303 GPVHPTPPPSSPQEPKRPSQLPSP---SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVS 4359
Query: 549 PSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
P+A Q + G G P PP ++P L N VPE + +
Sbjct: 4360 PAAAQLADTLFSKGLG-PWDPPDNLAETQKPEQSSLVPGHLDQVNGQV----VPEASQLS 4414
Query: 609 TCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTT 668
E + C+L + +KR G+ P + L P
Sbjct: 4415 IKQEPREEPCALGAQS-----------------VKREANGEPIGAPGTSNHLLLAGP--- 4454
Query: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728
+ A L K K V+ T GS +A+ DS
Sbjct: 4455 -----------------RSEAGHLLLQKLLRAKN----VQLSTGRGSEGLRAEINGHIDS 4493
Query: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTD-LVSSSSATTKPD---IPSSKVQ 784
K PS ++ A +PK V+ +D LVSS K D + ++
Sbjct: 4494 KLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLK 4553
Query: 785 SQAEEKTTPPLKTDSAKPSQS-FPPTG---------EKVSPFDSKAIPR-PASDSKIISH 833
+E + PL + + S F P G + F S A+P P S++++
Sbjct: 4554 QLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTK 4613
Query: 834 PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT----- 888
S+ + P +K ++P + PK + + T
Sbjct: 4614 NNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKS 4673
Query: 889 ------VPTPQQSPKPQEQSRRFSLNLGSITDAPKS-QPTTPQETVTGK 930
+PTP P Q+ + +D+P S P + E++ G+
Sbjct: 4674 LDLLAALPTP-----PHNQTEDVRMESDEDSDSPDSIVPASSPESILGE 4717
Score = 75.5 bits (184), Expect = 1e-12
Identities = 120/485 (24%), Positives = 173/485 (35%), Gaps = 107/485 (22%)
Query: 185 SQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQP 244
S ++ ++Q++ Q++Q LQQQ + + +QQ + LQQ + + QQ
Sbjct: 3896 SLQQLQQQQQLQQQQQ----------LQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQ 3945
Query: 245 EKIKSQPPGTGKPIQGPTQTPQTDHAK-----LPLQRDASRPQTKQADIVRGESVKPSLP 299
++++ Q + Q Q Q + L R PQ +Q V ++ P +P
Sbjct: 3946 QQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQV---ALGPGMP 4002
Query: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT-------------KPLAQQP 346
+ P P G E++ PA G + + +A +P
Sbjct: 4003 AKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEP 4062
Query: 347 GTVKPP---------VQPPGTTKPPAQPLGPA-KPPAQQT-----------------GSE 379
G VKP VQP +P + L P + P QQ GS
Sbjct: 4063 GEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSG 4122
Query: 380 KPSSEQPGPKALAQPP-GVGKTPAQQP----GPAKP----PTQQVGTPKPLAQQPGLQSP 430
S P LAQP +G P GP +P P Q P+P P LQS
Sbjct: 4123 SSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSG 4182
Query: 431 AKAPG----PT-------------KTP-VQQPGPGKIPAQQAGPGKTSAQQTGPTK--PP 470
PG PT K P ++ P + QA + QQ+ + PP
Sbjct: 4183 QGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPP 4242
Query: 471 SQLPGPAKPPPQQ-----------PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKP 519
Q PG P Q PGP P Q+ G+ P P PP
Sbjct: 4243 YQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVL 4302
Query: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP----LQPP--TVS 573
P P PP P K +Q PSP+ ++ P + G+ KP L+PP VS
Sbjct: 4303 GPVHP---TPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVS 4359
Query: 574 PSAKQ 578
P+A Q
Sbjct: 4360 PAAAQ 4364
Score = 67.0 bits (162), Expect = 5e-10
Identities = 293/1383 (21%), Positives = 452/1383 (32%), Gaps = 220/1383 (15%)
Query: 204 EGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEK--IKSQPPGTGKPIQGP 261
+G++ L QPP+ GP + + Q P ++ Q P + + +Q P
Sbjct: 3783 QGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQ 3842
Query: 262 TQTPQTDHAKLPLQRDASRPQTKQADIVRGES-VKPSLPSPSKPPIQQPTPGKPPAQQPG 320
H + Q+ + Q +Q + G S ++ SL S S P P Q
Sbjct: 3843 QGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQ 3902
Query: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
++ Q Q L + Q ++ Q + Q L + QQ ++
Sbjct: 3903 QQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQ--QQQ 3960
Query: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV--GTPKPLAQQPGLQSPAKAPGPTK 438
+Q + Q G+ P + QQV G P SP A GPT
Sbjct: 3961 QQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPG-ALGPTL 4019
Query: 439 --TPVQQPGPGKIPAQQAGPGKTSAQQTGP----TKPPSQLPGPAKPPPQQPGPAKPPPQ 492
T +Q + +A G S Q GP T P S P + P G ++
Sbjct: 4020 LLTGKEQNTVDPAVSSEATEGP-STHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLV 4078
Query: 493 QPGSAKPPSQQPGSTK--PPPQQPGPAKPSPQQPGSTKPPSQ-QPGSAKPSAQQPSP--- 546
QP P QP S + PP + PG + + S Q GS S P
Sbjct: 4079 QP----QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLL 4134
Query: 547 AKPSAQQSTKPVSQT----GSGKP-LQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHV 601
A+PS +P S T G +P L+ P + + QPP G P+ + + L
Sbjct: 4135 AQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPG------PVLQSGQGL--- 4185
Query: 602 PEKANFNTCTECQTTVCSLCGFNPN-PHLTEVKEWLCLNCQMKRALGGDLA--PVPSSPQ 658
P T + + + + NP HL+ ++ M+R L A P +
Sbjct: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245
Query: 659 PKLKTAPVTTTSAVSKSSPQPQQTS-PKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717
P +T+P+ QPQ P P Q+L P P+ PP L
Sbjct: 4246 PGTQTSPLQGLLGC-----QPQLGGFPGPQTGPLQELGAGPRPQGPPRL----------- 4289
Query: 718 AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD 777
PP A S P P+ P P + +PK+P +
Sbjct: 4290 ---PAPPGALSTGPVLGPVHPTPP------PSSPQEPKRPSQLPS--------------- 4325
Query: 778 IPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPS 837
PSS++ ++A+ PP + KP PT E P P S + +
Sbjct: 4326 -PSSQLPTEAQ---LPPTHPGTPKPQ---GPTLE----------PPPGRVSPAAAQLADT 4368
Query: 838 SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTA-GQTVPTPQQ-S 895
SKG DP E +K P+ S PG GQ VP Q S
Sbjct: 4369 LFSKGLGPWDPPDNLAETQK--------------PEQSSLVPGHLDQVNGQVVPEASQLS 4414
Query: 896 PKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPH 955
K + + +L S+ +P T SN + A GP
Sbjct: 4415 IKQEPREEPCALGAQSVKREANGEPIGAPGT----------------SNHLLLA---GPR 4455
Query: 956 SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015
S++G K A + STG+ I ++K LE K +
Sbjct: 4456 SEAGHLLLQKLLRA-------KNVQLSTGRGSEGLRAEINGHIDSKLAG---LEQKLQGT 4505
Query: 1016 PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP---KPESTCPLCKTELNIGSKD 1072
P+ K +KP K + A + KL K E+ K EL++
Sbjct: 4506 PSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLT 4565
Query: 1073 PPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGP 1132
P + C N L L T QL + P+ P
Sbjct: 4566 EPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGAL--PTGPDYYSQLLTKNNLSNPPTPP 4623
Query: 1133 KASPMPVPTESSSQK--TAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVT 1190
+ P P P S QK V P +L + + + L E S++ + + T
Sbjct: 4624 SSLP-PTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPT 4682
Query: 1191 TDQKQ-EESKLEKDKAS--------ALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKP 1241
Q E+ ++E D+ S A + L EE P R E++ L P
Sbjct: 4683 PPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIP 4742
Query: 1242 TPEDKKLLPEAKTSA-PEEQKHDLLKSQVQ-----IAEEKLEGRVAPKTVQEGKQPQTKM 1295
L+P A P+ + + L +V EK +G + +
Sbjct: 4743 ------LIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNL 4796
Query: 1296 EGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPK 1355
G+ + L + + + + P+ P A EP K + E K + P
Sbjct: 4797 NGVMVAVAELLSMKIPNSYEVL--FPESPARA---GTEPKKGEAEGPGGKEKGLEGKSP- 4850
Query: 1356 SPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPS-------SPSD 1408
DTG D + +P + DIL LK++S + E S D
Sbjct: 4851 ------DTG--PDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLD 4902
Query: 1409 LAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEI 1468
+ +L + S LA + T+P P +P + S L + S E
Sbjct: 4903 VRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPS---PLPLASSPESA 4959
Query: 1469 K---------ESQEERKDTFKK-------------DSQQDIPSSKDHKEKSEFVDDITTR 1506
+ E ++ R KK Q+ +D +E +EF++ + T
Sbjct: 4960 RPKPRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTA 5019
Query: 1507 REP 1509
P
Sbjct: 5020 LRP 5022
Score = 65.5 bits (158), Expect = 1e-09
Identities = 109/486 (22%), Positives = 171/486 (35%), Gaps = 75/486 (15%)
Query: 65 GLPKGSVPPA----AAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFR 120
G + +V PA A E PS H+ L P+ P +P+ G S+
Sbjct: 4023 GKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLV---- 4078
Query: 121 SEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180
Q P PS++ L+ +++ S + L + SS P L
Sbjct: 4079 --QPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQ 4136
Query: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ----QPPKPIPKQQGPGRDPLQQDGTP 236
S + ++ + Q G + +++ P+Q QPPKP P Q G P
Sbjct: 4137 PSVSLGDQ---PGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQ-------SGQGLP 4186
Query: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP 296
++++Q G + PQ H P Q+ + Q + + ++V+
Sbjct: 4187 GVGIMPTVGQLRAQLQGV------LAKNPQLRHLS-PQQQQQLQALLMQRQLQQSQAVRQ 4239
Query: 297 SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP--VQ 354
+ PP Q+P P Q G QP P +G + L P PP
Sbjct: 4240 T------PPYQEPGTQTSPLQ--GLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPA 4291
Query: 355 PPG--TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412
PPG +T P P+ P PP+ ++P S+ P P +Q P A+ P
Sbjct: 4292 PPGALSTGPVLGPVHPTPPPSSPQEPKRP-SQLPSPS------------SQLPTEAQLPP 4338
Query: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI-PAQQAGPGKTSAQQTGPTKPPS 471
GTPKP + P +P PG++ PA ++ GP PP
Sbjct: 4339 THPGTPKP-----------------QGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPD 4381
Query: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
L KP P Q G P + Q + P ++P + + P
Sbjct: 4382 NLAETQKPEQSSLVPGH-LDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPI 4440
Query: 532 QQPGSA 537
PG++
Sbjct: 4441 GAPGTS 4446
Score = 59.7 bits (143), Expect = 7e-08
Identities = 76/268 (28%), Positives = 95/268 (35%), Gaps = 32/268 (11%)
Query: 2369 QEKPASQLPSGS---PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
+E P S P S P LPA P P S + P PPP P PPP P
Sbjct: 454 EESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFS 513
Query: 2426 PL-PPPTSPKPTILPKKKL-TVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
PL P SP P L T SP A+PL + S P T+P
Sbjct: 514 PLEESPLSPPEESPPSPALETPLSPPPEASPL--------SPPFEESPLSPPPEELPTSP 565
Query: 2484 PP----VPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL-PTTTQKPTDIHPKPTGLSL 2538
PP + P P P P P + P++P P +L P + P P+ + LS
Sbjct: 566 PPEASRLSPPPEESPMS------PPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP 619
Query: 2539 TSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITL-PSEPGTPTDSSA 2597
+ D SP SP S S P L+ VV L P +P
Sbjct: 620 PPEASRLSPPPED----SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP 675
Query: 2598 SQAITSWPLGSPSKDLVSVEPVFSVVPP 2625
++ TS P P +S P S P
Sbjct: 676 EESPTSPP---PEASRLSPPPEDSPTSP 700
Score = 57.4 bits (137), Expect = 4e-07
Identities = 77/279 (27%), Positives = 104/279 (37%), Gaps = 48/279 (17%)
Query: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
PP + A P+ E L + +E P S P SP S P + PF S L+ S
Sbjct: 470 PPEELPASPLPEALHLSRPL------EESPLSPPPEESPL--SPPPESSPF---SPLEES 518
Query: 2403 AQPPPPPPPP---------PPPPPPPPPPP-------PPPLPPPTSPKP---TILPKKKL 2443
PP PP PPP P PP PPP PTSP P + P +
Sbjct: 519 PLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE 578
Query: 2444 TVASPVTTATPLFDAVTTLETTAVLRSNGL-PVTRICTTAPPPVPPKPSSIPSGLVFTHR 2502
+ SP +P+ + L P +PPP + S P +
Sbjct: 579 SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP 638
Query: 2503 PE--PSKPP-----IAPKPVIPQL-PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKL 2554
PE P PP ++P PV+ +L P + P P+ + S + D
Sbjct: 639 PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPED--- 695
Query: 2555 PSPTSPLSPHSNKSSPRFSKSL----TETYVVITLPSEP 2589
SPTSP P + +SP SL E ++ LP EP
Sbjct: 696 -SPTSP-PPEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732
Score = 54.3 bits (129), Expect = 3e-06
Identities = 223/1063 (20%), Positives = 335/1063 (31%), Gaps = 160/1063 (15%)
Query: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQ 285
GR+ + D + ++Q KI+ Q K + T K Q+ + Q +Q
Sbjct: 3553 GREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQ 3612
Query: 286 ADIVRGESVKPS------LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG-- 337
V S S LP P P PP Q G + PG P QP G
Sbjct: 3613 HSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPF 3672
Query: 338 LTKPLAQQ-----PGTVKPPVQPPGTTKP---PAQPLGPAKPPAQ--------------Q 375
L LAQQ G P G P + LGP Q Q
Sbjct: 3673 LNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQ 3732
Query: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP-----GLQSP 430
++ +Q L Q V QQ GP Q +G PKP P GL
Sbjct: 3733 KLQQQQQQQQQQQHLLGQ---VAIQQQQQQGPGVQTNQALG-PKPQGLMPPSSHQGLLVQ 3788
Query: 431 AKAPGPTKTPVQQPGPGKIPA-QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489
+P P + P GP ++ QQ PG GP P Q+ P A+
Sbjct: 3789 QLSPQPPQGPQGMLGPAQVAVLQQQHPG-----ALGPQGPHRQVLMTQSRVLSSPQLAQQ 3843
Query: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP-----SAQQP 544
G +QQ + QQ A S Q Q SA+P QQ
Sbjct: 3844 GQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQ 3903
Query: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEK 604
+ Q + Q + LQ + +Q Q + L + L ++
Sbjct: 3904 QQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQ--QLQQQQQQLQQQQQQ 3961
Query: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP----SSPQPK 660
+ Q L N + L ++ Q + ALG + P SSP
Sbjct: 3962 QQQQFQQQQQQQQMGL--LNQSRTLLSPQQ----QQQQQVALGPGMPAKPLQHFSSPGAL 4015
Query: 661 LKTAPVT--TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
T +T + V + P + PE P +P+L G
Sbjct: 4016 GPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQL 4075
Query: 719 KAKQP---PEADSLSKPAPPKEPSVPSEQ---------------DKAPVADDKPKQPKMV 760
QP P+ SL P + P +Q ++ +
Sbjct: 4076 LLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA 4135
Query: 761 KPTTDLVSSSSATTK----PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
+P+ L + T+ P P + Q PP + Q P G +
Sbjct: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVG 4195
Query: 817 DSKA-IPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGS 875
+A + + + + H P Q+Q+ + + + +++Q P +P + S
Sbjct: 4196 QLRAQLQGVLAKNPQLRHLSPQQ----QQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTS 4251
Query: 876 PTPP--GPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFG 933
P G +P G P PQ P + L G P P P TG + G
Sbjct: 4252 PLQGLLGCQPQLG-GFPGPQTGPLQE-------LGAGPRPQGPPRLPAPPGALSTGPVLG 4303
Query: 934 FGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ--------PPTSQGPPKSTGQ 985
P P S P P Q P+PS PPT G PK G
Sbjct: 4304 -------------PVHPTPPPSSPQEPKRP-SQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349
Query: 986 A-PPAPAKSIPVKKETKAPAAEK----LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEP 1040
P P + P + K +P A T K ++ P + D + P
Sbjct: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHL-DQVNGQVVP 4408
Query: 1041 QKAVLPTKLEKSPKPESTCPL----CKTELN---IGSKDPPNFNTCTECKNQVCNLCGFN 1093
+ + L K E +P C L K E N IG+ N +++ +L
Sbjct: 4409 EASQLSIKQEPREEP---CALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLL--- 4462
Query: 1094 PTPHLTEIQEWLCLNCQTQRAISGQLGDI------------RKMPPAPSGPK--ASPMPV 1139
L ++ + T R G +I +K+ PS + A+ P+
Sbjct: 4463 ----LQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPL 4518
Query: 1140 PTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSM 1182
+ + A V KK +E A + +L+++K+ LS+
Sbjct: 4519 TPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSL 4561
Score = 54.3 bits (129), Expect = 3e-06
Identities = 57/218 (26%), Positives = 95/218 (43%), Gaps = 10/218 (4%)
Query: 3193 EVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEE-----LEWERQEIQRFRE 3247
+V+ +S +L P+ +Q Q L R + ++ +QQ+ ++ L +Q +
Sbjct: 3826 QVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSG 3885
Query: 3248 QEKIMVQK--KLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQL-EQIQQLQQQLH 3304
Q K+ Q L++LQ +Q QQ +++Q Q + +Q+ L QQQLQ +Q QQLQQQ
Sbjct: 3886 QPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQ 3945
Query: 3305 QQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAALEGSQFWATEDATTTASAVVA 3364
QQL++Q+ + Q Q + +L L Q + A
Sbjct: 3946 QQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKP 4005
Query: 3365 IEIPQSQGWY--TVQSDGVTQYIAPPGILSTVSEIPLT 3400
++ S G T+ G Q P + S +E P T
Sbjct: 4006 LQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPST 4043
Score = 53.9 bits (128), Expect = 4e-06
Identities = 80/293 (27%), Positives = 110/293 (37%), Gaps = 33/293 (11%)
Query: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP----PPPPPPPPPPPP---- 2423
P P P S + P R S L + ++ PPP PPP P PPP
Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
Query: 2424 --PPPLPPPTSPKP---TILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT-R 2477
PPP PTSP P P + ++ S +PL E RS G ++ R
Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE--EPQLCPRSEGPHLSPR 746
Query: 2478 ICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLS 2537
P P +P P P+P +P + P P L + P + P+P L
Sbjct: 747 PEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP-HLSPQPEELH 805
Query: 2538 L---TSSMTLNLVTSADYKLPSP-TSPLSPHSNKS--SPR-----FSKSLTETYVVITLP 2586
L T L+ V P P S LSP S + SPR S L + +
Sbjct: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPE 865
Query: 2587 SEPGTPTDSSASQAITSW-PLGSPSKDLVSVEPVFSV--VPPVTAV--EIPIS 2634
P P A + + + P G PS + EP S PP++ + E+P+S
Sbjct: 866 KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS 918
Score = 53.9 bits (128), Expect = 4e-06
Identities = 97/392 (24%), Positives = 132/392 (33%), Gaps = 86/392 (21%)
Query: 214 QPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP-------------PGTGKP-IQ 259
+PP +P G P G + P + + P PGT P +
Sbjct: 2611 RPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMS 2670
Query: 260 GPTQTP---QTDHAKL-------PLQRDASRPQTKQADIVRGESVKPSL--PSPSKPPIQ 307
G +QT Q +L +QR+ R + + A G P PS P +
Sbjct: 2671 GLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFE 2730
Query: 308 QPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG 367
Q + G+ P + S G PP++ SG P+ PG+ P L
Sbjct: 2731 QLSRGQTPFAGTQDKSSLVG--LPPSKLSG--------------PILGPGSF-PSDDRLS 2773
Query: 368 PAKPPAQQTGSEKPSSEQPGPKAL--AQPPGVGKTPAQQPGPAKPPTQQV---------- 415
PPA + + S + G + P G P QQ QQ
Sbjct: 2774 RPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAM 2833
Query: 416 -----GTPKPLAQQPGLQSP-----AKAPGPTKTPVQQPGPGKIPAQ----------QAG 455
TP P + L SP + PGP + PV PGP PAQ G
Sbjct: 2834 SARFPSTPGPELGRQALGSPLAGISTRLPGPGE-PV--PGPAG-PAQFIELRHNVQKGLG 2889
Query: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP------PPQQPGSAKPPSQQPGSTKP 509
PG T GP + P P P P + PPQ+P SA P + S P
Sbjct: 2890 PGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKP-SAPPAPELNNSLHP 2948
Query: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA 541
P GP P+ + + P S + G P A
Sbjct: 2949 TPHTKGPTLPTGLELVNRPPSSTELGRPNPLA 2980
Score = 52.8 bits (125), Expect = 9e-06
Identities = 166/813 (20%), Positives = 258/813 (31%), Gaps = 125/813 (15%)
Query: 211 LQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA 270
LQQQ + K Q + QQ ++ QQ ++ Q PG QT+ A
Sbjct: 3723 LQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQ---QGPGV-----------QTNQA 3768
Query: 271 KLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAK 330
P + P + Q +V+ S +P Q P PAQ ++ PG
Sbjct: 3769 LGPKPQGLMPPSSHQGLLVQQLSPQPP---------QGPQGMLGPAQVAVLQQQHPGALG 3819
Query: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA 390
P P Q T + P + +G AQQ ++ +Q
Sbjct: 3820 PQG-------PHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAG 3872
Query: 391 LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP 450
L+ + ++ G K Q +G+ + L QQ LQ + +QQ ++
Sbjct: 3873 LSH---LQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQ--------LQQQQQQQLQ 3921
Query: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
QQ + QQ + Q + QQ + QQ + QQ G
Sbjct: 3922 QQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQS 3981
Query: 511 PQQPGPAKPSPQQ----PGSTKPPSQQ---PGSAKPS----AQQPSPAKPSAQQSTKPVS 559
P + QQ PG P Q PG+ P+ ++ + P+
Sbjct: 3982 RTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGP 4041
Query: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619
T G PL T S P + P L ++LLL P+
Sbjct: 4042 STHQGGPLAIGTTPESMATEPGEVKPS----LSGDSQLLLVQPQP--------------- 4082
Query: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP 679
P P +++ L L Q ++ + L +L + + S+V QP
Sbjct: 4083 ----QPQPSSLQLQPPLRLPGQQQQQVSL-LHTAGGGSHGQLGSGSSSEASSVPHLLAQP 4137
Query: 680 QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPS 739
+ + + Q+L +P P+ P P P P+
Sbjct: 4138 SVSLGDQPGSMTQNLLGPQQPMLERPMQNNT----GPQPPKPGPVLQSGQGLPGVGIMPT 4193
Query: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDS 799
V Q +A + K P++ L + + ++Q + TPP +
Sbjct: 4194 VG--QLRAQLQGVLAKNPQL----RHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPG 4247
Query: 800 AKPSQ------------SFPPTGEKVSPFDSK-AIPRPASDSKIISHPGPSSESKGQKQV 846
+ S FP G + P A PRP ++ + PG S V
Sbjct: 4248 TQTSPLQGLLGCQPQLGGFP--GPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPV 4305
Query: 847 DPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFS 906
P P++ PK P P+P PT Q PT +PKPQ
Sbjct: 4306 HPTPPPSSPQE------PK-----RPSQLPSPSSQLPTEAQLPPTHPGTPKPQ------- 4347
Query: 907 LNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ 966
G + P + + + LF G + NL T Q S PG + Q
Sbjct: 4348 ---GPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAET--QKPEQSSLVPG-HLDQ 4401
Query: 967 APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKE 999
P SQ K + P + VK+E
Sbjct: 4402 VNGQVVPEASQLSIKQEPREEPCALGAQSVKRE 4434
Score = 47.8 bits (112), Expect = 3e-04
Identities = 71/274 (25%), Positives = 94/274 (34%), Gaps = 41/274 (14%)
Query: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP------PPPPPP 2422
QE P +Q + SP P+ P F S D AQPP P P PPPP PP P
Sbjct: 2350 QEPPPAQALAPSP-----PSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLP 2404
Query: 2423 PPPPLPPPTSPKPTILPKKKLT---------VASPVTTATPLFDAVTTLETTAVLRSNGL 2473
P P SP+ + LT SPVT D + + R
Sbjct: 2405 SDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFA 2464
Query: 2474 PVTRICTTAPPPVPPKPSSIPSGLVFTHRPE---PSKPPIAPKPVIPQLPTTTQKPTDIH 2530
P+ + P P PP+ + L T P+ P P + + Q P +
Sbjct: 2465 PLHK----PPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVR 2520
Query: 2531 PKPTGLSLTSSMTLNL-----VTSADYKLPSPTSPLSPHSNKSS-----PRFSKSLTETY 2580
TG + + + V K P P L P +S P K + Y
Sbjct: 2521 SPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNY 2580
Query: 2581 VVIT---LPS-EPGTPTDSSASQAITSWPLGSPS 2610
V T PS P P+ S ++ PL PS
Sbjct: 2581 TVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPS 2614
Score = 46.6 bits (109), Expect = 6e-04
Identities = 77/294 (26%), Positives = 108/294 (36%), Gaps = 41/294 (13%)
Query: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPP- 2429
+PA P G P +S LP + P S +S Q PP P PPP P PP L P
Sbjct: 897 EPALSEP-GEPPLSPLPEE-LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPL 954
Query: 2430 -----PTSPKPTILPKKKLTVASPVTTATPLFDAVTT----LETTAVLRSNGLPVTRICT 2480
P K P+ L T +P +A T + + S G PV
Sbjct: 955 GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASP 1014
Query: 2481 TAPPPVPPKPSSIPSGLVFTHRPEP-SKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLS-- 2537
P+PP+ S + H P + PP P P LP + P K G+S
Sbjct: 1015 ILMEPLPPQCSPL-----LQHSLVPQNSPPSQCSP--PALPLSVPSPLSPIGKVVGVSDE 1067
Query: 2538 ----------LTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPR---FSKSLTETYVVIT 2584
++ L SA LPSP LS + +P FS +T +
Sbjct: 1068 AELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDG 1127
Query: 2585 LPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQT 2638
+ + P ++ S GSP V ++P + PVT +E+ +QT
Sbjct: 1128 IDAPGSQPEPGQTPGSLASELKGSP----VLLDP--EELAPVTPMEVYPECKQT 1175
Score = 45.8 bits (107), Expect = 0.001
Identities = 115/513 (22%), Positives = 169/513 (32%), Gaps = 52/513 (10%)
Query: 2169 PSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDS----- 2223
P ES S PP +P S + + S P L++ + E + FE+S
Sbjct: 498 PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPP 557
Query: 2224 -EEISSSTYFPGSIIDYPEEISVSLD--RTAPPDGRASADHIVISLSDMASSIIESVVPK 2280
EE+ +S S + P E S +P A + + S P
Sbjct: 558 PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPL 617
Query: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEV--LEAYRDKKELEAERTKSSLS-- 2336
P A +S E P+ +E+ EV L L +S LS
Sbjct: 618 SPPPEASRLSPP---PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
Query: 2337 --ETVFDHPPSSVIALPMKEQLSTTY--FTSGETFGQEKPASQLPSGSPSVSSLPAKPRP 2392
E+ PP + P E T+ S + E LP + LP +P+
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734
Query: 2393 FFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA 2452
RS +S +P P P P P P P P +P + + SP
Sbjct: 735 CPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794
Query: 2453 TPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAP 2512
L L + L PVP +P P P+ +P ++P
Sbjct: 795 PHLSPQPEELHLSPQTEEPHL----------SPVPEEPCLSPQPEESHLSPQSEEPCLSP 844
Query: 2513 KPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTS-PLSPHSNKSSPR 2571
+P L +KP + P+P + P+P PL P + P
Sbjct: 845 RPEESHLSPELEKP-PLSPRP-----------EKPPEEPGQCPAPEELPLFPPPGE--PS 890
Query: 2572 FSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEI 2631
S L E + SEPG P S + + P G PS + P +PP + I
Sbjct: 891 LSPLLGEPAL-----SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPP--DPLPPPLSPII 943
Query: 2632 PISSEQTFYISGALQ-TFSATPVTAPSSFQAAP 2663
++ G L+ F A + P S AAP
Sbjct: 944 TAAAPPALSPLGELEYPFGAKGDSDPESPLAAP 976
Score = 45.4 bits (106), Expect = 0.001
Identities = 51/205 (24%), Positives = 71/205 (34%), Gaps = 21/205 (10%)
Query: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP----PPPPLPPPTS 2432
P G V P P L + P PPP P PPP PPP P S
Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS 477
Query: 2433 PKPTILPKKKLTVASPVT--------TATPLFDAVTTLETTAVLRSNGLPVTRICTTAPP 2484
P P L + SP++ + P + LE + + P + T
Sbjct: 478 PLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET--- 534
Query: 2485 PVPPKPSSIPSGLVFTH---RPEPSKPPIAPKPVIPQL-PTTTQKPTDIHPKPTGLS--L 2538
P+ P P + P F P P + P +P P +L P + P P+ + +S
Sbjct: 535 PLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPP 594
Query: 2539 TSSMTLNLVTSADYKLPSPTSPLSP 2563
+S + P SPLSP
Sbjct: 595 EASRLFPPFEESPLSPPPEESPLSP 619
Score = 42.4 bits (98), Expect = 0.012
Identities = 68/317 (21%), Positives = 109/317 (34%), Gaps = 68/317 (21%)
Query: 2363 SGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP 2422
+G G + P P V + PF + + + + P PP PP P P P
Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206
Query: 2423 PPPPL------------------PP------PTSPKPTILPK----KKLTV--------- 2445
PP+ PP P++P P + P+ L V
Sbjct: 2207 AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG 2266
Query: 2446 --ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTH-- 2501
+ P+ + P ++ LE + + ++P PP + S TH
Sbjct: 2267 KASEPLLSPPPFGESRKALE---------VKKEELGASSPSYGPPNLGFVDSPSSGTHLG 2317
Query: 2502 -----RPEPSKPPIAPK--PVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKL 2554
P+ K P+ P+ V PQ P +P + P L+ + ++ Y
Sbjct: 2318 GLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE-PPPAQALAPSPPSHPDIFRPGSYTD 2376
Query: 2555 PSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSE-----PGTPTDSSASQA-ITSWPLGS 2608
P PL+P P +L +LPS+ P +P S+SQ+ +T PL +
Sbjct: 2377 PYAQPPLTPRPQPPPPESCCALPPR----SLPSDPFSRVPASPQSQSSSQSPLTPRPLSA 2432
Query: 2609 PSKDLVSVEPVFSVVPP 2625
+ V P F P
Sbjct: 2433 EAFCPSPVTPRFQSPDP 2449
Score = 40.0 bits (92), Expect = 0.060
Identities = 31/91 (34%), Positives = 40/91 (43%), Gaps = 15/91 (16%)
Query: 2369 QEKPASQLP---SGSPSVSSLPAKPRPFFRSSSLDISAQPP--PPPPPPPPPPPPPPPPP 2423
QE PA + P S + +VS+L + +SA PP P PPP P P P PP
Sbjct: 4881 QESPAPEPPTQHSYTYNVSNLDVR----------QLSAPPPEEPSPPPSPLAPSPASPPT 4930
Query: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
P + PT P L +AS +A P
Sbjct: 4931 EPLVELPTEPLAEPPVPSPLPLASSPESARP 4961
Score = 39.7 bits (91), Expect = 0.078
Identities = 48/184 (26%), Positives = 74/184 (40%), Gaps = 25/184 (13%)
Query: 3553 ISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKK--RPTPLEIGYSSHLRADSTV 3610
+S PE++ +L ++ P S SPP ++ P P E+ S A
Sbjct: 520 LSPPEESPPSPAL------ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEAS--- 570
Query: 3611 QLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPK 3670
+L+P P +SP SP+SP F P+E+ SP L P + P + P
Sbjct: 571 RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE------SP---LSPPPEESPLSPPP 621
Query: 3671 TAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPE 3730
A + D P+SP +ES +P ++ S S + + +PPPE
Sbjct: 622 EASRLSPPPED-SPMSPPPEESPMSP----PPEVSRLSPLPVVSRLSPPPEESPLSPPPE 676
Query: 3731 EIST 3734
E T
Sbjct: 677 ESPT 680
Score = 39.3 bits (90), Expect = 0.10
Identities = 40/130 (30%), Positives = 56/130 (43%), Gaps = 15/130 (11%)
Query: 3572 DSDTQSPQYLSATSPPKDKKR--PTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP 3629
+S P S TSPP + R P P E+ S A + P SP SP+SP
Sbjct: 446 ESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP 505
Query: 3630 LSPGKALESAFVPYEK-PL--PDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLS 3686
P ++ S F P E+ PL P++ P L ++ P ASP + + PLS
Sbjct: 506 --PPES--SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF------EESPLS 555
Query: 3687 PTADESSRAP 3696
P +E +P
Sbjct: 556 PPPEELPTSP 565
Score = 38.5 bits (88), Expect = 0.17
Identities = 81/346 (23%), Positives = 123/346 (35%), Gaps = 67/346 (19%)
Query: 2167 SEPSESATSVPPSDTPSLTSSVSSVCTTDS---------------------SSPITTLDS 2205
S P +S+PP+ PS+ + + T +S + +LD
Sbjct: 4617 SNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDL 4676
Query: 2206 ITTVYTEPVDMITKFE-DSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVI 2264
+ + T P + +S+E S S P SI+ S+ L AP +
Sbjct: 4677 LAALPTPPHNQTEDVRMESDEDSDS---PDSIVPASSPESI-LGEEAPRFPHLGSGRW-- 4730
Query: 2265 SLSDMASSIIESVVPKPEGPV-ADTV---STDLLISEKDPVKKAKKETGNGIILEVLEAY 2320
D A S + ++P+ PV DT + L + K PV +K G+ + + + +
Sbjct: 4731 EQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSA 4790
Query: 2321 RDKKELEAERTKSSLSETVFDHPPSSV-IALPMKEQLSTTYFTSGETFGQEKPASQLPSG 2379
K L +++E + P+S + P + T GE G L
Sbjct: 4791 AAAKNLNGVMV--AVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGK 4848
Query: 2380 SPS-----VSSLPAKPRPFFRSSSLDISA----QPPPPPPP------------------- 2411
SP + A + S LDI + + P P PP
Sbjct: 4849 SPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSA 4908
Query: 2412 PPPPPPPPPPPP--PPPLPPPTSPKPTILPKKKLTVASPVTTATPL 2455
PPP P PPP P P P PPT P LP + L PV + PL
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPL-VELPTEPL-AEPPVPSPLPL 4952
Score = 37.4 bits (85), Expect = 0.39
Identities = 52/213 (24%), Positives = 74/213 (34%), Gaps = 12/213 (5%)
Query: 1697 PELEMESLTDSPEDRSRGEGSSSLHAS---SFTPGTSPTSVSSLDEDSDSSPSHKKGESK 1753
P E L+ PE+ +LH S +P + P S L +SSP ES
Sbjct: 460 PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP 519
Query: 1754 QQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDE 1813
P L + E L E E+ +S+ S ++
Sbjct: 520 LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579
Query: 1814 LRAQRRRERPKTPPSNLS----PIEDA--SPTEELRQAAEMEELHRSSCSEYSPSIESDP 1867
+ E P +PP S P E++ SP E + E R S + P
Sbjct: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP 639
Query: 1868 EGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQS 1900
E +SP EV ++ LP VS SP E+S
Sbjct: 640 EESPMSPPP--EVSRLSPLP-VVSRLSPPPEES 669
Score = 36.2 bits (82), Expect = 0.86
Identities = 49/195 (25%), Positives = 70/195 (35%), Gaps = 17/195 (8%)
Query: 2420 PPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRIC 2479
PP P PP + PTI + SP T A A L+ A +
Sbjct: 2107 PPQPGALGSPPPAAAPTIF------IGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELF 2160
Query: 2480 TTAPPPVPPK-PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSL 2538
PP VP + PS P GL + EP + P AP P P P+ T P +P L
Sbjct: 2161 LKLPPQVPAQVPSQDPFGLAPAYPLEP-RFPTAP-PTYPPYPSPTGAPA----QPPMLGA 2214
Query: 2539 TSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSAS 2598
+S ++ P +P H + F K + + +P PG ++
Sbjct: 2215 SSRPGAG--QPGEFHTTPPGTP--RHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASE 2270
Query: 2599 QAITSWPLGSPSKDL 2613
++ P G K L
Sbjct: 2271 PLLSPPPFGESRKAL 2285
Score = 36.2 bits (82), Expect = 0.86
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 2336 SETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPA---SQLPSGSPSVSSLPAKPRP 2392
SE + + LP+ E T F+ FG P SQL G+ +LP P
Sbjct: 4548 SEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQL-RGAFGSGALPTGPDY 4606
Query: 2393 FFRSSSLDISAQPPPPPPPPPPPPPP 2418
+ + + + + PP PP PP PPP
Sbjct: 4607 YSQLLTKNNLSNPPTPPSSLPPTPPP 4632
Score = 35.8 bits (81), Expect = 1.1
Identities = 25/68 (36%), Positives = 26/68 (38%), Gaps = 10/68 (14%)
Query: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
QE A P G P LPA P L P P PPP P P P LP
Sbjct: 4275 QELGAGPRPQGPPR---LPAPPGALSTGPVLG-------PVHPTPPPSSPQEPKRPSQLP 4324
Query: 2429 PPTSPKPT 2436
P+S PT
Sbjct: 4325 SPSSQLPT 4332
Score = 35.4 bits (80), Expect = 1.5
Identities = 37/130 (28%), Positives = 48/130 (36%), Gaps = 36/130 (27%)
Query: 2400 DISAQPPPPPPPPPPPPPP-----PPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
++ A P P PP P PP P P P PPP+SP+ PK+ + SP
Sbjct: 4276 ELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQE---PKRPSQLPSP------ 4326
Query: 2455 LFDAVTTLETTAVLRSN--GLPVTRICTTAPPPVPPKPSSI----------------PSG 2496
+ L T A L G P + T PPP P++ P
Sbjct: 4327 ----SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDN 4382
Query: 2497 LVFTHRPEPS 2506
L T +PE S
Sbjct: 4383 LAETQKPEQS 4392
Score = 34.7 bits (78), Expect = 2.5
Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 6/83 (7%)
Query: 2362 TSGETFGQEKPASQLPSGSPSVSSLPAK-PRPFFRSSSLDISAQPPPPPPPPPPPPPPPP 2420
++G G P P SP P++ P P SS L AQ PP P P P P
Sbjct: 4297 STGPVLGPVHPTP--PPSSPQEPKRPSQLPSP---SSQLPTEAQLPPTHPGTPKPQGPTL 4351
Query: 2421 PPPPPPLPPPTSPKPTILPKKKL 2443
PPP + P + L K L
Sbjct: 4352 EPPPGRVSPAAAQLADTLFSKGL 4374
Score = 33.9 bits (76), Expect = 4.3
Identities = 51/184 (27%), Positives = 72/184 (39%), Gaps = 32/184 (17%)
Query: 3572 DSDTQSPQYLS-ATSPPKDKKRPTPLEIGYSSHLRADSTVQLAP-------SP-PKSPKV 3622
DS T P S A+ PP+D PLE S L QL P SP P+ P +
Sbjct: 695 DSPTSPPPEDSPASPPPEDSLMSLPLE--ESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL 752
Query: 3623 LYSPISP-LSPGKALESAFVPYEKPLPDD-----------ISPQKVLHPDMAKVPPA--- 3667
P P LSP A P+ P P++ +SPQ P ++ P
Sbjct: 753 SPRPEEPHLSP-----QAEEPHLSPQPEEPCLCAVPEEPHLSPQAE-GPHLSPQPEELHL 806
Query: 3668 SPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNP 3727
SP+T + + + LSP +ES +P + + ++ S +K P
Sbjct: 807 SPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEK 866
Query: 3728 PPEE 3731
PPEE
Sbjct: 867 PPEE 870
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 156 bits (394), Expect = 6e-37
Identities = 336/1607 (20%), Positives = 567/1607 (35%), Gaps = 327/1607 (20%)
Query: 41 MEADLSQLSEEERRQIAA---VMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSG 97
+EA+ ++++E + ++I + ++ + P VP A + + ++++ + P K+
Sbjct: 9547 VEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKK---IVPEKKVPAPVPKKEKV 9603
Query: 98 RPPD-PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGF 156
PP P P +P K + E+ LP + + + + K +
Sbjct: 9604 PPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKAR 9663
Query: 157 LSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPP 216
+ E + V K P + E + T +++VV++E+ E P + QP
Sbjct: 9664 VPEEPKRAVPEEKVLKLKPK---REEEPPAKVTEFRKRVVKEEKVSIEA---PKREPQPI 9717
Query: 217 KPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQR 276
K + + R ++ +++S Q+ E+ + K + T + D + +R
Sbjct: 9718 KEVTIMEEKERAYTLEE---EAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEER 9774
Query: 277 DASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPS 336
+ R + + I +P P P KP ++P P KP A PPA+
Sbjct: 9775 EYERYEEHEEYIT-----EPEKPIPVKPVPEEPVPTKPKA--------------PPAKVL 9815
Query: 337 GLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ-----TGSEKPSSEQPGPKAL 391
P + P + ++PP PP P P K ++ T EK +P K
Sbjct: 9816 KKAVPEEKVPVPIPKKLKPP----PPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVP 9871
Query: 392 AQPPGVGKTPAQQPGPAK---PPTQQVGTPKPLAQQPGLQS------------------- 429
+P V + P P K PP + PK L +
Sbjct: 9872 MKPKRV-VAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYI 9930
Query: 430 ----------------PAKAPGPTKTPV-QQPGPGKIP-AQQAGPGKTSAQQTGP-TKPP 470
P K P + PV ++ P +P ++A P K P K P
Sbjct: 9931 HEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVP 9990
Query: 471 SQLPGPAKPPPQQ--PGPAKPPPQQPGSAKPPSQ---QPGSTKPPPQQPGPAK--PSPQQ 523
+P KPPP + P KP P++ P + P P++P P K P P
Sbjct: 9991 VLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAP 10050
Query: 524 PGSTKPPSQQPGSAK---PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ-- 578
PP++ P K P ++P+P + P +P+ P P ++
Sbjct: 10051 KKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVE--APPPKVPKKREPVPVPVALPQEEEVL 10108
Query: 579 ------PPSQGLPKTICPLCNTTELLLH----VPEKANFNTCTECQTTVCSLCGFNPNPH 628
P + LP+ L E+L +PE+ E V + P
Sbjct: 10109 FEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEE---EVPPEEEYVPEEE 10165
Query: 629 LTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDA 688
+E + + K PVP +P P++K K + + PKK+
Sbjct: 10166 EFVPEEEVLPEVKPK-------VPVP-APVPEIK-----------KKVTEKKVVIPKKEE 10206
Query: 689 APKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAP 748
AP + + P+ + ++ P ++P E + P + PS+ ++ AP
Sbjct: 10207 APPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAP 10266
Query: 749 VADDKPKQPKMVK--------PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT--- 797
P+ P+++K P V + A IP KV ++K PP K
Sbjct: 10267 -----PRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEV 10321
Query: 798 --------------DSAKPSQSFPPTGEKVS-PFDSKAIPRPASDSKIIS---HPGPSSE 839
++ P++ EKVS F + + + + +++ P E
Sbjct: 10322 PKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEE 10381
Query: 840 S---------------------------KGQKQVDPVQKKEEPKKA-QTKMSPKPDAKPM 871
+ + +V+ V + E +A + ++ KP A P
Sbjct: 10382 EFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPK 10441
Query: 872 ----------PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921
PK PT PR VP + +E+ R + + P+ PT
Sbjct: 10442 GPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVR--------VPEEPRVPPT 10493
Query: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981
E + K + + + A +P P AP + P P PP
Sbjct: 10494 KVPEVLPPK------EVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPV----PPP 10543
Query: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041
+ PP +P + E + PK E P E + P + K + A P
Sbjct: 10544 KKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPP----PEVPEAPKEVVPEKKVPAAPP 10599
Query: 1042 K--AVLPTKLEKSPK---PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTP 1096
K V P K+ ++PK PE P+ PP K +V P
Sbjct: 10600 KKPEVTPVKVPEAPKEVVPEKKVPV----------PPPK-------KPEV-------PPT 10635
Query: 1097 HLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQ---------- 1146
+ E+ + + AI PP P P P E + +
Sbjct: 10636 KVPEVPKVAVPEKKVPEAI----------PPKPESPPPEVFEEPEEVALEEPPAEVVEEP 10685
Query: 1147 KTAVPPQVKLVKKQEQEVKTEAEKVILEK-----------VKETLSMEKIPPMVTTDQKQ 1195
+ A PPQV + K+ K +A V+ +K KE + +K+P +V +
Sbjct: 10686 EPAAPPQVTVPPKKPVPEK-KAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA 10744
Query: 1196 EESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKK--PTPEDKKLLP--- 1250
+K+ + + EKK +K +P K+ KKP+LEEK P PE + P
Sbjct: 10745 PPAKVPEVPKEVVPEKKVAVPKKPEVP-PAKVPEVPKKPVLEEKPAVPVPERAESPPPEV 10803
Query: 1251 --EAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQ---PQTKMEGL--PSGTP 1303
E + APEE+ + V +AEE+ E V P V E + P+ K+ + P P
Sbjct: 10804 YEEPEEIAPEEEIAPEEEKPVPVAEEE-EPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPP 10862
Query: 1304 QSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDT 1363
P E +K + K +P+PP P P ++ EK + P+ PQ
Sbjct: 10863 PKEP-EPEKVIEKPKLKPRPP---PPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQ----- 10913
Query: 1364 GYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQ 1423
+ + P +P EK + K L E P P + L+S + E +
Sbjct: 10914 ------VPEKVELTPLKVPGGEKKVRKLL------PERKP-EPKEEVVLKSVLRKRPEEE 10960
Query: 1424 ASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKE 1470
+ +K EK +P P PK E+ E +T E +I E
Sbjct: 10961 EPKVEPKKLEKVKKPAVPEPPPPKPVEEV----EVPTVTKRERKIPE 11003
Score = 155 bits (393), Expect = 7e-37
Identities = 291/1402 (20%), Positives = 481/1402 (34%), Gaps = 237/1402 (16%)
Query: 66 LPKGSVPPAAAESPSMHRKQELDSSHPP---KQSGRPPDPGRPAQPGL---SKSRTTDTF 119
+P+ VP P+ K+ + P + +PP P P +P K R + T
Sbjct: 9798 VPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITK 9857
Query: 120 RSEQ-------KLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNA--LSAVSSVV 170
R ++ K+P + ++ E K KE +P E+ ++ VV
Sbjct: 9858 REKEQVTEPAAKVPMKPKRVVA--EEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVV 9915
Query: 171 NKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL 230
+ + + E EE ++ + +E+ P +K P + P KP+P+++ P P
Sbjct: 9916 THVEEYLVEEEEEYIHEE----EEFITEEEVVPVIPVKVP--EVPRKPVPEEKKPVPVPK 9969
Query: 231 QQDGTPKSISS---QQPEKI-----KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ 282
+++ P + + EK+ K + P K + P + + +P+ + P
Sbjct: 9970 KKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPP 10029
Query: 283 TKQADIVRGESVKPSLPSPSKPPIQQP---TPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339
K ++ + + +P P+ ++ P P P P +K P P K A P +
Sbjct: 10030 AKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVP 10089
Query: 340 KPLAQQPGTVKPP----------VQPPGTTKPPAQPLGPAK----PPAQQTGSEK----P 381
K P V P + P P + + P + P ++ E+ P
Sbjct: 10090 KKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPP 10149
Query: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
E+ P+ P P ++ P P V P P ++ + P + P
Sbjct: 10150 EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAP- 10208
Query: 442 QQPGPGKIPAQQAG--------PGKTSAQQTGPTKPPSQLPG-----PAKPPPQQPGPAK 488
P K+P P + T+ P + P P +PP +
Sbjct: 10209 ----PAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEV 10264
Query: 489 PPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548
PP+ P K + + P + PAK S + P P Q A P+ P K
Sbjct: 10265 APPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKK 10324
Query: 549 PSAQQSTKPVSQT---GSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKA 605
++ P + G+ + VS + +Q + + K L + +PE+
Sbjct: 10325 VPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQ---EVVVKERLELEVVEAEVEEIPEEE 10381
Query: 606 NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLN---------------------CQMKR 644
F+ E + EV+E++ L +
Sbjct: 10382 EFHEVEE----------YFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVE 10431
Query: 645 ALGGDLAPVPSSPQPKLKTAPVTT--TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK 702
AP P P+ K P T V + P + K ++ + EP+
Sbjct: 10432 VFEKPKAP-PKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRV 10490
Query: 703 PPPLVKQ--PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSE---QDKAPVADDKPKQP 757
PP V + P P K PP + PPK P P E + K PV PK+P
Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKP--EAPPPKVPEAPKEVVPEKKVPVPP--PKKP 10546
Query: 758 KMVKPTTDLVSSSSATTKPDIPSS---KVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS 814
+ V PT +A + +P + K +S E P + K + PP +V+
Sbjct: 10547 E-VPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVT 10605
Query: 815 PFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP-KKAQTKMSPKPDA----- 868
P P+ K + P P +V V K P KK + PKP++
Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEV 10665
Query: 869 --KPMPKGSPTPPG-----PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921
+P PP P P A V P + P P++++ + P P
Sbjct: 10666 FEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELP--PVKVPE 10723
Query: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981
P+E V K P P A + + P P PK
Sbjct: 10724 VPKEVVPEKKVPLVV-----------------PKKPEAPPAKVPEVPKEVVPEKKVAVPK 10766
Query: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041
+ PPA +P K P E+ P V E + PPP + P+
Sbjct: 10767 KP-EVPPAKVPEVPKK------------PVLEEKPAVPVPERAESPPPEVYEEPEEIAPE 10813
Query: 1042 KAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEI 1101
+ + P E+ P P + ++ P P P + E
Sbjct: 10814 EEIAPE--EEKPVP------------VAEEEEPEV-----------------PPPAVPE- 10841
Query: 1102 QEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQE 1161
+ ++ I + + K P AP + P V E K PP K++
Sbjct: 10842 --------EPKKIIPEKKVPVIKKPEAPPPKEPEPEKV-IEKPKLKPRPPPPPPAPPKED 10892
Query: 1162 QEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKL-----EKDKASALQEKKPLPE 1216
+ K K I +K K+P +K E + L EK L E+KP P+
Sbjct: 10893 VKEKIFQLKAIPKK--------KVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPK 10944
Query: 1217 EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKL 1276
E+ ++ + R EE++P +E KK K +PE P E +V++
Sbjct: 10945 EEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVE--------EVEVPTVTK 10996
Query: 1277 EGRVAPKTVQEGKQPQTKME-GLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPG 1335
R P+ K P+ K LP+ P+ P+ + KT K +P+P A P V
Sbjct: 10997 RERKIPEPT---KVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVV 11053
Query: 1336 KEKTEKEDDKSDTSSSQQPKSP 1357
+K E + K + + +PK P
Sbjct: 11054 GKKAEAKAPKEEAA---KPKGP 11072
Score = 124 bits (310), Expect = 3e-27
Identities = 185/848 (21%), Positives = 299/848 (35%), Gaps = 135/848 (15%)
Query: 35 TAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPK 94
T +P +EA +++S++ + V + + P VP + P K+ L PK
Sbjct: 10282 TPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPE---KKVL----VPK 10334
Query: 95 QSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSS--M 152
+ PP GR + + + + FR E + R + E + + +E H+
Sbjct: 10335 KEAVPPAKGRT----VLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYF 10390
Query: 153 MPGFLSEVNALSAVSSV-------VNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEG 205
G EV + V K + +I EA + E +K K K E
Sbjct: 10391 EEGEFHEVEEFIKLEQHRVEEEHRVEKVHR--VIEVFEAEEVEVFEKPKAPPKGPEISEK 10448
Query: 206 IIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP-------------- 251
II P ++ P K +P+++ P + P PK I ++ ++ +P
Sbjct: 10449 IIPP--KKPPTKVVPRKEPPAKVP----EVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPK 10502
Query: 252 ----------PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG---ESVKPSL 298
P KP P + P+ +P ++ P K+ ++ E K ++
Sbjct: 10503 EVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVP-EKKVPVPPPKKPEVPPTKVPEVPKAAV 10561
Query: 299 PSPSKPPIQQPTPGKPPAQQPGHEKS----QPGPAKPPAQPSGLTKPLAQQPGTVKP--- 351
P P P P PP + P K + PA PP +P + + P V P
Sbjct: 10562 PEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKK 10621
Query: 352 -PVQPPGTTKPPAQPLGPAKPPAQQTGSEK------PSSEQPGPKALAQPPGVG--KTPA 402
PV PP KP P + P +K P E P P+ +P V + PA
Sbjct: 10622 VPVPPP--KKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPA 10679
Query: 403 Q---QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG--PTKTPV---------------- 441
+ +P PA PP V KP+ ++ AK P P K P
Sbjct: 10680 EVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVP 10739
Query: 442 --QQPGPGKIPA--QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
+ P K+P ++ P K A P PP+++P K P + PA P P++ S
Sbjct: 10740 KKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESP 10799
Query: 498 KP-----PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS--QQPGSAKPSAQQPSPAKPS 550
P P + + P++ P + ++ PP+ ++P P + P KP
Sbjct: 10800 PPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPE 10859
Query: 551 AQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLL----HVPEKAN 606
A +P + KP P P PP + + + I L + + VPEK
Sbjct: 10860 APPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVE 10919
Query: 607 FNTC-----------------TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGD 649
E + V P E K + K+
Sbjct: 10920 LTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPK------VEPKKLEKVK 10973
Query: 650 LAPVPSSPQPK-LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVK 708
VP P PK ++ V T + + P+P + K A P P+P+ +K
Sbjct: 10974 KPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIK 11033
Query: 709 QPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVS 768
P + P+ A P + K A K P + + K P+ K P ++ +
Sbjct: 11034 PPPVEPEPTPIA-APVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLR 11092
Query: 769 SSSATTKP 776
S KP
Sbjct: 11093 PGSGGEKP 11100
Score = 121 bits (304), Expect = 2e-26
Identities = 187/773 (24%), Positives = 271/773 (35%), Gaps = 176/773 (22%)
Query: 313 KPPAQQPGHEKSQP--GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370
KP A G E S+ P KPP + +P A+ P K V P + P K
Sbjct: 10435 KPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTK 10494
Query: 371 PPA----QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG 426
P ++ EK P K A PP V + P + P ++V P P ++P
Sbjct: 10495 VPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVV-----PEKKVPVPPP--KKPE 10547
Query: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP-GPAKPPPQQPG 485
+ P K P K V + K+P +A P K P PP ++P P + P++
Sbjct: 10548 VP-PTKVPEVPKAAVPEK---KVP--EAIPPK-------PESPPPEVPEAPKEVVPEKKV 10594
Query: 486 PAKPP----------PQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSPQQPGSTKPPSQQP 534
PA PP P+ P P + P PPP++P P P+ P P + P
Sbjct: 10595 PAAPPKKPEVTPVKVPEAPKEVVPEKKVP---VPPPKKPEVPPTKVPEVPKVAVPEKKVP 10651
Query: 535 GSAKPSAQQPSPA---KPSAQQSTKPVSQT-GSGKPLQPPTVSPSAKQPPSQGLPKTICP 590
+ P + P P +P +P ++ +P PP V+ K+P
Sbjct: 10652 EAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKP----------- 10700
Query: 591 LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDL 650
VPEK + V P L VK + ++
Sbjct: 10701 ----------VPEK-------KAPAVVAK------KPELPPVKV---------PEVPKEV 10728
Query: 651 APVPSSPQ--PKLKTAPVTTTSAVSKSS-PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707
P P PK AP V K P+ + PKK P +K PE K P L
Sbjct: 10729 VPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPP---AKVPEVPKKPVLE 10785
Query: 708 KQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK---------PKQPK 758
++P + P PPE + P+E P E+ PVA+++ P++PK
Sbjct: 10786 EKPAVP-VPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPK 10844
Query: 759 MVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDS 818
+ P + KP+ P K + P LK P + P K F
Sbjct: 10845 KIIPEKKV----PVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQL 10900
Query: 819 KAIPR------PASDSKIISHP--GPSSESKGQKQVD---PVQKKE---------EPKKA 858
KAIP+ P K+ P P E K +K + P K+E P++
Sbjct: 10901 KAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEE 10960
Query: 859 QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKS 918
+ K+ PK K P PP P+P VPT + + + T P+
Sbjct: 10961 EPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRER----------KIPEPTKVPEI 11010
Query: 919 QPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG 978
+P P P P + P A +K +PP +
Sbjct: 11011 KPAIPL---------------------------PAPEPKPKPEAEVKTI----KPPPVE- 11038
Query: 979 PPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIK 1031
P+ T A P + K E KAP E +PK K+T P PI+
Sbjct: 11039 -PEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKT-----PSPIE 11085
Score = 111 bits (278), Expect = 2e-23
Identities = 313/1574 (19%), Positives = 567/1574 (36%), Gaps = 242/1574 (15%)
Query: 70 SVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRS 129
S PPA E P +E P K+ PP P PA P + + +P
Sbjct: 9394 SPPPAVPEIPKKKVPEERKPV-PRKEEEVPPPPKVPALP----KKPVPEEKVAVPVPVAK 9448
Query: 130 PSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVV----NKFNPFDLISDSEAS 185
+ E +T ++E+ F++E AV V ++ + + S SE
Sbjct: 9449 KAPPPRAEVSKKTVVEEKR-------FVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEE 9501
Query: 186 QEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE 245
+ + + ++E+ + + + + ++P + + +++ + + P ++ +Q +
Sbjct: 9502 EGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISK-RVEAEPAEVTERQEK 9560
Query: 246 KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTK-QADIVRGESVKP-SLPSPSK 303
KI +P + P + + AK+P P+ K A + + E V P +P K
Sbjct: 9561 KIVLKP-------KIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPK 9613
Query: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
P+ P PP + +P PAK + +T+ K + P + P
Sbjct: 9614 KPV--PEKKVPPKVI---KMEEPLPAKVTERHMQITQEEKVLVAVTKK--EAPPKARVPE 9666
Query: 364 QPLGPAKPPAQQTGSEKPSSEQPGP-------KALAQPPGVG-KTPAQQPGPAKPPTQQV 415
+P P ++ KP E+ P K + + V + P ++P P K T
Sbjct: 9667 EPKRAV--PEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIME 9724
Query: 416 GTPKPLAQQPGLQSPAKAPG----------------PTKTPVQQPGPGKIPAQQAGPGKT 459
+ + S + PT+ Q ++ +
Sbjct: 9725 EKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYE-----EYEEREYERY 9779
Query: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPAKP--PPQQPGSAKPPSQQ-----PGSTKPP-- 510
+ T+P + P P KP P++P P KP PP + P ++ P KPP
Sbjct: 9780 EEHEEYITEP--EKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPP 9837
Query: 511 --PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQ 568
P++P + TK +Q +P+A+ P K + PV + P++
Sbjct: 9838 KVPEEPKKVFEEKIRISITKREKEQ--VTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVR 9895
Query: 569 PPTVSPSAKQPPSQGLPKTICPLCNTTELLL-----HVPEKANFNTCTECQTTVCSLCGF 623
P V P +P + + + + E L+ ++ E+ F T E +
Sbjct: 9896 VPEV-PKELEPEEVAFEEEV--VTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPE 9952
Query: 624 NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQT- 682
P + E K+ PV P PK K AP V K +
Sbjct: 9953 VPRKPVPEEKK-----------------PV---PVPKKKEAPPAKVPEVPKKPEEKVPVL 9992
Query: 683 SPKKDAAPKQDLSKAPE-PKKPPPLVKQPTLHGSPSAKAKQPPEA---DSLSKPAPPKEP 738
PKK+ P +K PE PKKP P K P P K + P A + KP P K+
Sbjct: 9993 IPKKEKPPP---AKVPEVPKKPVPEEKVPV----PVPKKVEAPPAKVPEVPKKPVPEKKV 10045
Query: 739 SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP----- 793
VP+ + P+ PK + P + + K + P KV + E P
Sbjct: 10046 PVPAPKKVEAPPAKVPEVPKKLIP--EEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQ 10103
Query: 794 ---PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG--PSSESKGQKQVDP 848
L + P + P E+V P + + +P + +++ P E + + +
Sbjct: 10104 EEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLP---EEEEVLPEEEEIPPEEEEVPPEEEY 10160
Query: 849 VQKKEEPKKAQTKMSPKPDAKP-MPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSL 907
V ++EE + + P+ KP +P +P P + + V P++ P
Sbjct: 10161 VPEEEEFVPEEEVL---PEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAP--------- 10208
Query: 908 NLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967
P P P++ ++ I + ++ P + P+ +
Sbjct: 10209 --------PAKVPEVPKKVEEKRI------ILPKEEEVLPVEVTEEPEEE-----PISEE 10249
Query: 968 PAPSQPPTSQ-----GPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022
P +PP+ + PP+ P K++P E P +K+E A A K+
Sbjct: 10250 EIPEEPPSIEEVEEVAPPR----VPEVIKKAVP---EAPTPVPKKVE--APPAKVSKKIP 10300
Query: 1023 TEKKPPPIKDSKSLTAE--------PQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPP 1074
EK P P++ ++ A+ P+K VL K E P P + + ++++ +
Sbjct: 10301 EEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVP-PAKGRTVLEEKVSVAFRQEV 10359
Query: 1075 NFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKA 1134
E + + E++E+ G+ ++ + K
Sbjct: 10360 VVKERLELEVVEAEVEEIPEEEEFHEVEEYF---------EEGEFHEVEEF------IKL 10404
Query: 1135 SPMPVPTESSSQKTAVPPQVKLVKKQEQEV--KTEAEKVILEKVKETLSMEKIPPMVTTD 1192
V E +K V +++ + +E EV K +A E + E + K PP
Sbjct: 10405 EQHRVEEEHRVEK--VHRVIEVFEAEEVEVFEKPKAPPKGPE-ISEKIIPPKKPPTKVVP 10461
Query: 1193 QKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEA 1252
+K+ +K+ + KK + EEK +PEE ++ + +L K+ PE K +P A
Sbjct: 10462 RKEPPAKVPE------VPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPA 10515
Query: 1253 KTSAPEEQKHDLLKSQVQIAEEKLEGRVAPK--TVQEGKQPQTKMEGLP-SGTPQSLPKE 1309
K PE + ++ ++ EK PK V K P+ +P P+++P +
Sbjct: 10516 K--KPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPK 10573
Query: 1310 DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDG 1369
E P P P +V P K+ K + + + P++P+ +
Sbjct: 10574 --------PESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEV----VPEKK 10621
Query: 1370 ISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAK--LESTVLSILEAQASTL 1427
+ + P + PT ++ K + E+ P P E LE + +
Sbjct: 10622 VPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEV 10681
Query: 1428 ADEKSEKKTQPHEVSPEQPKDQEKTQSL---SETLEITISEEEIKESQEERKDTFKKDSQ 1484
+E V P++P ++K ++ L E KE E+K +
Sbjct: 10682 VEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKK 10741
Query: 1485 QDIPSSKDHKEKSEFVDD--ITTRREPYDSVEESSESENSPVPQRKRRTSV---GSSSSD 1539
+ P +K + E V + + ++P + E PV + K V S
Sbjct: 10742 PEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPP 10801
Query: 1540 EYKQEDSQGSGEEE 1553
E +E + + EEE
Sbjct: 10802 EVYEEPEEIAPEEE 10815
Score = 106 bits (265), Expect = 5e-22
Identities = 268/1361 (19%), Positives = 498/1361 (36%), Gaps = 179/1361 (13%)
Query: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTK 360
P+K P ++ P ++P EK + + + +TK P K V +
Sbjct: 9166 PAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKV----PEVSKKIVPQKPSRT 9221
Query: 361 PPAQPLGPAKPPAQQTGSEKPSSEQ------PGPKALAQPPGVGKTPAQQPGPAKPPTQQ 414
P + + K PA T S E+ + P V K + +++
Sbjct: 9222 PVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKR 9281
Query: 415 VGTPKPLAQQPGLQSPAK-APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473
V P + + P +P + AP P V+ P P K+P P K ++ P P +
Sbjct: 9282 VEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAP-KVPEV---PKKPVPEEKKPVPVPKK- 9336
Query: 474 PGPAKPPPQQPGPAKPPPQQ----PGSAK---PPSQQPGSTKP----------PPQQPGP 516
PA PP P KP P++ P + K PP++ P K ++ P
Sbjct: 9337 -EPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESP 9395
Query: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
P+ P P ++P K P P P+ + KPV + K P V+ A
Sbjct: 9396 PPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPK--KPVPEE---KVAVPVPVAKKA 9450
Query: 577 KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636
P ++ KT+ E EK +F + T ++ +EW
Sbjct: 9451 PPPRAEVSKKTV-----VEEKRFVAEEKLSFAVPQRVEVT---------RHEVSAEEEW- 9495
Query: 637 CLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS----PKKDAAPKQ 692
+ G ++ + + + A VT + + + K+ A
Sbjct: 9496 ---SYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPA 9552
Query: 693 DLSKAPEPK-----KPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE----PSVPSE 743
++++ E K K P +++P P A K PE + P P KE P VP E
Sbjct: 9553 EVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEK-KVPAPVPKKEKVPPPKVP-E 9610
Query: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS 803
+ K PV + K PK++K L + + KV +K PP +P
Sbjct: 9611 EPKKPVPEKKVP-PKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPK 9669
Query: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS 863
++ P EKV K P P+ ++ +K+V KEE + +
Sbjct: 9670 RAVPE--EKVLKLKPKREEEP-----------PAKVTEFRKRV----VKEEKVSIE---A 9709
Query: 864 PKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP 923
PK + +P+ + + R + Q + E+ + + + +PT
Sbjct: 9710 PKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYK-----EFEEYEPTEE 9764
Query: 924 QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKST 983
+ + + + I+ +P P P+ + P P++P P K
Sbjct: 9765 YDQYE-EYEEREYERYEEHEEYITEPEKPIPVK------PVPEEPVPTKPKAP--PAKVL 9815
Query: 984 GQAPPAPAKSIPVKKETKAPAAE-KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQK 1042
+A P +P+ K+ K P + EPK ++ + T+++ + + + K
Sbjct: 9816 KKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPK 9875
Query: 1043 AVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQ 1102
V+ + P+ E P+ E+ +P E V ++ E +
Sbjct: 9876 RVVAEEKVPVPRKEVAPPVRVPEVP-KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEE 9934
Query: 1103 EWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQ 1162
E++ + + + ++P P + P+PVP +K A P +V V K+ +
Sbjct: 9935 EFIT----EEEVVPVIPVKVPEVPRKPVPEEKKPVPVP----KKKEAPPAKVPEVPKKPE 9986
Query: 1163 EVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIP 1222
E K+P ++ +K +K+ + KKP+PEEK +P
Sbjct: 9987 E--------------------KVPVLIPKKEKPPPAKVPE------VPKKPVPEEKVPVP 10020
Query: 1223 EEEKIRSEEKKPLLEEKKPTPEDKKLLP-EAKTSAPEEQKHDLLKSQVQIAEEKLEGRVA 1281
+K+ + K KKP PE K +P K AP + ++ K I EEK V
Sbjct: 10021 VPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKK--LIPEEKKPTPV- 10077
Query: 1282 PKTVQEGKQPQTKMEGLPSGTPQSLPKEDDK--TTKTIKEQPQPP-----------CTAK 1328
PK V E P+ + P P +LP+E++ + + E+ P +
Sbjct: 10078 PKKV-EAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPE 10136
Query: 1329 PDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDI 1388
++V P +E+ E+++ P+ + + + + +P+ +P +K +
Sbjct: 10137 EEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPE--VKPKVPVPAPVPEIKKKV 10194
Query: 1389 LKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTL---ADEKSEKKTQPHEVSPEQ 1445
+ +E+ P+ ++ K IL + L E+ E++ E PE+
Sbjct: 10195 TEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEE 10254
Query: 1446 PKDQEKTQSLS-----ETLEITISEEEI---KESQEERKDTFKKDSQQDIPSSKDHKEKS 1497
P E+ + ++ E ++ + E K+ + KK ++ +P KE
Sbjct: 10255 PPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAP 10314
Query: 1498 EFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIR 1557
++ P V + VP K RT + S ++QE E + +
Sbjct: 10315 PAKVPEVPKKVPEKKV---LVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVE 10371
Query: 1558 KQIIEMSADEDASGSED--DEFIRNQLKEISSSTESQKKEE 1596
++ E+ +E+ E+ +E ++++E + + +EE
Sbjct: 10372 AEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEE 10412
Score = 75.5 bits (184), Expect = 1e-12
Identities = 148/687 (21%), Positives = 268/687 (39%), Gaps = 119/687 (17%)
Query: 992 KSIPVK-KETKAPAAEKLEPKAEQAPTVKRTE-TEKKPPPIKDSKSLTAEPQKAVLPTKL 1049
+ +P K E KAP PK + P +++ E T ++ K + E K ++P K
Sbjct: 9163 RKVPAKVPEKKAPPP----PKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKP 9218
Query: 1050 EKSPKPESTC----PLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWL 1105
++P E P T+ + S++ F + TE + V + E+Q+ +
Sbjct: 9219 SRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVT----------VPEVQKEI 9268
Query: 1106 CLNCQTQRAISGQLGDIRKMP----------------------PAPSGPKASPMPVPTES 1143
+ AIS ++ K+P PAP P+ PVP E
Sbjct: 9269 VTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEK 9328
Query: 1144 S-----SQKTAVPPQVKLVKKQ---EQEV------KTEAEKVILEKV-KETLSMEKIPPM 1188
++ A PP+V V K+ E+++ K EA + +V K ++ EKI +
Sbjct: 9329 KPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIV 9388
Query: 1189 VTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKL 1248
++ + E K +E+KP+P +++ +P K+ + KKP+ EEK P
Sbjct: 9389 TQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVP----- 9443
Query: 1249 LPEAKTSAP---EEQKHDLLKSQVQIAEEKLEGRVAPK--------TVQEGKQPQTKMEG 1297
+P AK + P E K +++ + +AEEKL V + + +E + EG
Sbjct: 9444 VPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEG 9503
Query: 1298 LPSGTPQSLPKEDDK----TTKTIKEQPQP-------PCTAKPDQVEPGKEKTEKEDDKS 1346
+ + +E+++ T + E+P+ +K + EP E TE+++ K
Sbjct: 9504 VSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPA-EVTERQEKK- 9561
Query: 1347 DTSSSQQPKSPQGLSDTGYSS--DGISSSLGE--IPSLIPTDEKDILKGLKKDSFSQESS 1402
+PK P + + + + + E +P+ +P EK + ++
Sbjct: 9562 ---IVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPE 9618
Query: 1403 PSSPSDLAKLESTV-LSILEAQASTLADEK-----SEKKTQPHEVSPEQPK---DQEKTQ 1453
P + K+E + + E +EK ++K+ P PE+PK +EK
Sbjct: 9619 KKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVL 9678
Query: 1454 SLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSV 1513
L E EE + E RK K++ S + K + + + ++T E
Sbjct: 9679 KLKPKRE----EEPPAKVTEFRKRVVKEEK----VSIEAPKREPQPIKEVTIMEE----- 9725
Query: 1514 EESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSE 1573
+E + + +R +YK+ + EE D Q E E E
Sbjct: 9726 KERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYD----QYEEYEEREYERYEE 9781
Query: 1574 DDEFIRNQLKEISSSTESQKKEETKGK 1600
+E+I K I ++ TK K
Sbjct: 9782 HEEYITEPEKPIPVKPVPEEPVPTKPK 9808
Score = 65.9 bits (159), Expect = 1e-09
Identities = 171/852 (20%), Positives = 312/852 (36%), Gaps = 137/852 (16%)
Query: 1766 LLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKT 1825
+LP EEE EEE+ +E E+E+ + KK E + + +
Sbjct: 10232 VLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPK-KVEA 10290
Query: 1826 PPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYK 1885
PP+ +S P E++ + +E + E + PEK + V K
Sbjct: 10291 PPAKVSK---KIPEEKVPVPVQKKEAPPAKVPEVPKKV----------PEKKVLVPKKEA 10337
Query: 1886 LPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEKEP 1945
+P A ++ S+ ++ + E+ E + + + + F +E +E FE+
Sbjct: 10338 VPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEF---HEVEEYFEEGE 10394
Query: 1946 LYGGMLIEDYIY--ESLVEDTYNGSVDGSLLT--RQEEENGFMQQKGREQKIRLSEQIY- 2000
+ +E++I + VE+ + ++ EE F + K + +SE+I
Sbjct: 10395 FHE---VEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIP 10451
Query: 2001 -----------EDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFI---IPESHEIVDLG 2046
++P K+ ++ K+ E + VP+E V + + +P + +
Sbjct: 10452 PKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVR--VPEEPRVPPTKVPEVLPPKEVVPEKK 10509
Query: 2047 TMVTSTEE-ERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIG-EDMTESTMDFDRMPDA 2104
V ++ E A +E++ +++ + P P P ++ ++ + ++P+A
Sbjct: 10510 VPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEA 10569
Query: 2105 SLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHESLIL 2164
+ ++ +P+ K+ + + E E + + E +
Sbjct: 10570 IPPKPESPPPEVPEAPKEV---VPEKKVP---AAPPKKPEVTPVKVPEAPKEVVPEKKVP 10623
Query: 2165 TYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSE 2224
P VPP+ P V V + P ++I P + FE+ E
Sbjct: 10624 V---PPPKKPEVPPTKVPE----VPKVAVPEKKVP----EAIPPKPESPPPEV--FEEPE 10670
Query: 2225 EISSSTYFPGSIIDYPEEISVSLDRTAP----PDGRASA------DHIVISLSDMASSII 2274
E++ P +++ PE + P P+ +A A + + + ++ ++
Sbjct: 10671 EVALEEP-PAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVV 10729
Query: 2275 ES-----VVPK-PEGPVADTVSTDL-LISEKDPVKKAKKETGNGIILEVLEAYRDKKELE 2327
VVPK PE P A ++ EK K E + EV KK +
Sbjct: 10730 PEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEV-----PKKPVL 10784
Query: 2328 AERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVS--S 2385
E+ + E + PP V P E+++ + E +EKP P V +
Sbjct: 10785 EEKPAVPVPERA-ESPPPEVYEEP--EEIAPEEEIAPE---EEKPVPVAEEEEPEVPPPA 10838
Query: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP-------PPPPPPPPPLPPPTSPKPTI- 2437
+P +P+ + + +P PPP P P P PPPPPP PP K I
Sbjct: 10839 VPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIF 10898
Query: 2438 ----LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493
+PKKK+ P P +E T + G R P P + +
Sbjct: 10899 QLKAIPKKKV----PEKPQVP-----EKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVL 10949
Query: 2494 PSGLVFTHRPEPSKPPIAP-------KPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNL 2546
S V RPE +P + P KP +P+ P PKP + +
Sbjct: 10950 KS--VLRKRPEEEEPKVEPKKLEKVKKPAVPEPPP---------PKP-----VEEVEVPT 10993
Query: 2547 VTSADYKLPSPT 2558
VT + K+P PT
Sbjct: 10994 VTKRERKIPEPT 11005
Score = 63.5 bits (153), Expect = 5e-09
Identities = 179/906 (19%), Positives = 330/906 (36%), Gaps = 149/906 (16%)
Query: 1122 IRKMPPAPSGPK-ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETL 1180
IR +PP P A P+P+ + +K P ++++ KK VK +A+KV+ K KE
Sbjct: 8949 IRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKA---VKKDAKKVVA-KPKEMT 9004
Query: 1181 SMEKI-----PPMVTTDQKQEE-----SKLEKDKASALQEKKPLPEEKKLIPEEEKIRSE 1230
E+I PP K E SK E+ K + KK + +EK+ + E+++ +
Sbjct: 9005 PREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHK 9064
Query: 1231 EKKPLLEE----------------------KKPTPEDKKLLPEAKTSAPEE--------- 1259
EK+ +E ++P + +++ EAK EE
Sbjct: 9065 EKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQ 9124
Query: 1260 --------------------QKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLP 1299
Q+ ++++ Q ++ EE E +V K ++ P K+ P
Sbjct: 9125 EYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKP 9184
Query: 1300 -----SGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQP 1354
T + + +E + TK + E + KP + +E E + T +
Sbjct: 9185 VIEKIEKTSRRMEEEKVQVTK-VPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHT--KKMV 9241
Query: 1355 KSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES 1414
S + + ++ + +S ++ E+ I T+EK I + K P P A E
Sbjct: 9242 ISEEKMFFASHTEEEVSVTVPEVQKEIVTEEK-IHVAISKRVEPPPKVPELPEKPAPEEV 9300
Query: 1415 TVLSI---LEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKES 1471
+ I +E A + + + + + P K+ + E + + EE+I
Sbjct: 9301 APVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVP 9360
Query: 1472 QEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRRE-PYDSVEESSE----SENSPVPQ 1526
++K+ +P + E + +T R E P +V E + E PVP+
Sbjct: 9361 VAKKKEA----PPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPR 9416
Query: 1527 RKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEIS 1586
K+E+ + +K + E ++ R E+S
Sbjct: 9417 ---------------KEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPR---AEVS 9458
Query: 1587 SSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSW-HDEDDEAFDESPELKY 1645
T ++K + A R + S +E+ W + E++E S Y
Sbjct: 9459 KKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEE------WSYSEEEEGVSIS---VY 9509
Query: 1646 RETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLT 1705
RE + +E EE VT ++ +E ++Y E S + EP +T
Sbjct: 9510 REEEREEEEEAEVT------EYEVME----EPEEYVVEEKLHIISKRVEAEP----AEVT 9555
Query: 1706 DSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGP 1765
+ E + + P P + + + K E K P P
Sbjct: 9556 ERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKV---PEEP 9612
Query: 1766 LLPTIEDSSEEEELREEEEL-LKEQEKQREIEQQQR--KSSSKKSKKDKDELRAQRRRER 1822
P E + ++ EE L K E+ +I Q+++ + +KK K + + +R
Sbjct: 9613 KKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAV 9672
Query: 1823 PKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQK 1882
P+ L P + P A++ E + E SIE+ P+ I EV
Sbjct: 9673 PEEKVLKLKPKREEEP------PAKVTEFRKRVVKEEKVSIEAPKR----EPQPIKEVTI 9722
Query: 1883 VYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAANERD-EVF 1941
+ + A Y+ +E +Q+E + + + E T +Y + ER+ E +
Sbjct: 9723 MEEKERA---YTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERY 9779
Query: 1942 EKEPLY 1947
E+ Y
Sbjct: 9780 EEHEEY 9785
Score = 56.2 bits (134), Expect = 8e-07
Identities = 100/541 (18%), Positives = 189/541 (34%), Gaps = 63/541 (11%)
Query: 83 RKQELDSSHPPKQSGR------PPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLK 136
+K+ + SH K + PP P +P + K T E+K+ +S K
Sbjct: 9153 QKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKK 9212
Query: 137 ---ESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQ 193
+ SRT ++EE +P ++ +S ++ Q+E ++
Sbjct: 9213 IVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEE 9272
Query: 194 KV---VQK------------EQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKS 238
K+ + K E+ PE + P+ ++ P PK + P+ ++ P
Sbjct: 9273 KIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVP 9332
Query: 239 ISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSL 298
+ ++P P KP+ + +P+ + P K ++ +G + +
Sbjct: 9333 VPKKEPAAPPKVPEVPKKPV-------PEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKI 9385
Query: 299 ---------PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349
P P+ P I + + P E+ P P K PA P KP+ ++ V
Sbjct: 9386 TIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPK---KPVPEEKVAV 9442
Query: 350 KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK 409
PV PP + K ++ ++ +E+ A+ Q V +
Sbjct: 9443 PVPV---AKKAPPPRAEVSKKTVVEE---KRFVAEEKLSFAVPQRVEVTRHEVSAEEEWS 9496
Query: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ--------QAGPGKTSA 461
++ G + ++ + +A +++P + + +A P + +
Sbjct: 9497 YSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTE 9556
Query: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK-PPPQQP-GPAKP 519
+Q ++P + PP P P P K P+ P K PPP+ P P KP
Sbjct: 9557 RQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVP-EKKVPAPVPKKEKVPPPKVPEEPKKP 9615
Query: 520 SPQQ---PGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
P++ P K P Q + + TK + + P +P P
Sbjct: 9616 VPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEE 9675
Query: 577 K 577
K
Sbjct: 9676 K 9676
Score = 54.7 bits (130), Expect = 2e-06
Identities = 77/370 (20%), Positives = 127/370 (34%), Gaps = 47/370 (12%)
Query: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP---------- 2419
+KP +++ + +P P+ + + +P PP P PP
Sbjct: 10453 KKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPV 10512
Query: 2420 PPPPPPPLPPPTSPK--PTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTR 2477
PP P PPP P+ ++P+KK+ V P P + + +
Sbjct: 10513 PPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPP 10572
Query: 2478 ICTTAPPPVPPKPSS-IPSGLVFTHRPE-----PSKPPIAPKPVIPQ--LPTTTQKPTDI 2529
+ PP VP P +P V P+ P K P APK V+P+ +P K ++
Sbjct: 10573 KPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEV 10632
Query: 2530 HPKPTGLSLTSSMTLNLVTSADYKLPS--PTSPLSPHSNKSSPRFSKSLTETYVVITLPS 2587
P T + V + K+P P P SP +L E +
Sbjct: 10633 PP-------TKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEP 10685
Query: 2588 EPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQT 2647
EP P Q P K +V +PPV E+P +
Sbjct: 10686 EPAAP-----PQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVP----------KEVVP 10730
Query: 2648 FSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDN 2707
P+ P +A P V + V + +V+ + P V + + +P +P+ +
Sbjct: 10731 EKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKK--PEVPPAKVP-EVPKKPVLEEK 10787
Query: 2708 IHLEKPQYKE 2717
+ P+ E
Sbjct: 10788 PAVPVPERAE 10797
Score = 53.1 bits (126), Expect = 7e-06
Identities = 146/696 (20%), Positives = 253/696 (36%), Gaps = 123/696 (17%)
Query: 960 PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVK 1019
P P + P P+ P + P + PP A IP+ T E+ P K
Sbjct: 8935 PDIPDSRVPIPTMPIRAVPPE----EIPPVVAPPIPLLLPTPE----------EKKPPPK 8980
Query: 1020 RTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTE--LNIGSK-DPPNF 1076
R E KK KD+K + A+P++ ++ K P P +T K +++ SK +
Sbjct: 8981 RIEVTKKAVK-KDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKI 9039
Query: 1077 NTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGP-KAS 1135
T T K E+Q+ + ++A+ + + P +
Sbjct: 9040 MTITRKK----------------EVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVE 9083
Query: 1136 PMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQ 1195
P P E P + + +E+K EA+K + E+ +E E+ ++
Sbjct: 9084 PYTEPFEQ--------PYYEEPDEDYEEIKVEAKKEVHEEWEE--DFEEGQEYYEREEGY 9133
Query: 1196 EESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLP----- 1250
+E E++ A QE++ + +K++ E + + K P E+K P P P
Sbjct: 9134 DEG--EEEWEEAYQEREVIQVQKEVYEESHERKVPAKVP--EKKAPPPPKVIKKPVIEKI 9189
Query: 1251 EAKTSAPEEQKHDLLK-------------SQVQIAEEKLEGRVAPKTVQEGKQPQTKM-- 1295
E + EE+K + K S+ + EE +E +V ++ + KM
Sbjct: 9190 EKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFF 9249
Query: 1296 ----EGLPSGTPQSLPKE---DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDT 1348
E S T + KE ++K I ++ +PP P E ++ +E
Sbjct: 9250 ASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPP----PKVPELPEKPAPEEVAPVPI 9305
Query: 1349 SSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSD 1408
+P +P+ + E+P +EK + KK+ + P P
Sbjct: 9306 PKKVEPPAPK---------------VPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKK 9350
Query: 1409 -----------LAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSE 1457
K E+ + E Q + +EK TQ E P + K + E
Sbjct: 9351 PVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEE 9410
Query: 1458 TLEITISEEEI----KESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSV 1513
+ EEE+ K +K ++ +P +K V T E
Sbjct: 9411 RKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVA 9470
Query: 1514 EESSESENSPVPQRKRRTSVGSSSSDEYK-QEDSQGSG-----EEEDFIRKQIIEMSADE 1567
EE + VPQR T S+ +E+ E+ +G EEE R++ E E
Sbjct: 9471 EEKL---SFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEE---REEEEEAEVTE 9524
Query: 1568 DASGSEDDEF-IRNQLKEISSSTESQKKEETKGKGK 1602
E +E+ + +L IS E++ E T+ + K
Sbjct: 9525 YEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEK 9560
Score = 53.1 bits (126), Expect = 7e-06
Identities = 111/537 (20%), Positives = 178/537 (33%), Gaps = 90/537 (16%)
Query: 2139 EEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVP-PSDTPSLTSSVSS---VCTT 2194
EE+ E +Y E +E + E ++ E VP P+ P + V+ V
Sbjct: 10152 EEVPPE--EEYVPEEEEFVPEEEVL------PEVKPKVPVPAPVPEIKKKVTEKKVVIPK 10203
Query: 2195 DSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPD 2254
+P + + E ++ K E+ P + + PEE +S + P+
Sbjct: 10204 KEEAPPAKVPEVPKKVEEKRIILPKEEE--------VLPVEVTEEPEEEPISEEEI--PE 10253
Query: 2255 GRASADHIVISLSDMASSIIESVVPKPEGPVADTVS------TDLLISEKDPVKKAKKET 2308
S + + +I+ VP+ PV V + + EK PV KKE
Sbjct: 10254 EPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEA 10313
Query: 2309 GNGIILEVLEAYRDKKEL--EAERTKSSLSETVFDHPPS--------------------S 2346
+ EV + +KK L + E + TV + S
Sbjct: 10314 PPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAE 10373
Query: 2347 VIALPMKEQLSTT--YFTSGETFGQEKPASQLPSGSPSVSSLPAKPR---PFFRSSSLDI 2401
V +P +E+ YF GE F + + +L K F + +++
Sbjct: 10374 VEEIPEEEEFHEVEEYFEEGE-FHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEV 10432
Query: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPK--KKLTVASPVTTATPLFDAV 2459
+P PP P PP PP P P +P+ KK+ V
Sbjct: 10433 FEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVE------------- 10479
Query: 2460 TTLETTAVLRSNGLPVTRICTTAPPP--VPPKPSSIPSGLVFTHRPE--PSKPPIAPKPV 2515
E V +P T++ PP VP K +P +PE P K P APK V
Sbjct: 10480 ---EKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPA----KKPEAPPPKVPEAPKEV 10532
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
+P+ P PT + + + P P SP P ++
Sbjct: 10533 VPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP--------PPEVPEA 10584
Query: 2576 LTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIP 2632
E +P+ P + + + + P K + P VPP E+P
Sbjct: 10585 PKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVP 10641
Score = 50.1 bits (118), Expect = 6e-05
Identities = 50/190 (26%), Positives = 90/190 (47%), Gaps = 13/190 (6%)
Query: 187 EETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEK 246
E+ +K +K + K E ++K L+++P + PK + + +++ P+ + E+
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEE 10988
Query: 247 IKSQPPGTGKP--IQGPTQTPQTDHAKLPLQRDASRPQTK-QADIVRGESVKPSLPSPSK 303
++ P T + I PT+ P+ A +PL +P+ + + ++ V+P P+P
Sbjct: 10989 VEV-PTVTKRERKIPEPTKVPEIKPA-IPLPAPEPKPKPEAEVKTIKPPPVEPE-PTPIA 11045
Query: 304 PPIQQPTPGKPP-AQQPGHEKSQP-GPAK--PPAQPSGLT---KPLAQQPGTVKPPVQPP 356
P+ P GK A+ P E ++P GP K P PS + + L G KPP + P
Sbjct: 11046 APVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAP 11105
Query: 357 GTTKPPAQPL 366
T + A PL
Sbjct: 11106 FTYQLKAVPL 11115
Score = 49.7 bits (117), Expect = 8e-05
Identities = 87/421 (20%), Positives = 163/421 (38%), Gaps = 65/421 (15%)
Query: 985 QAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAV 1044
Q P IP K ++++P + KA+ A + P P++ ++ T P ++V
Sbjct: 248 QLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSV 307
Query: 1045 LP-TKLEKSPKPESTCPLC--KTELN---IGSKDPPNFNTCTECKNQVCNLCGFNPTPHL 1098
P ++ SP PL KT+ + G + PP + + V + + +
Sbjct: 308 SPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQ----EGYVAS----SSEAEM 359
Query: 1099 TEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVK 1158
E +T+ G+ G ++ SG + V +S AV K VK
Sbjct: 360 RETTLTTSTQIRTEERWEGRYGVQEQV--TISGAAGAAASVSASASYAAEAVATGAKEVK 417
Query: 1159 KQEQE---VKTEAEKVILEKVKETL--SMEKIPPMVTT-----DQKQEESKLEKDKAS-- 1206
+ + V T V + +V+E + ++E+ TT QE+ + E +K +
Sbjct: 418 QDADKSAAVATVVAAVDMARVREPVISAVEQTAQRTTTTAVHIQPAQEQVRKEAEKTAVT 477
Query: 1207 --ALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQK--- 1261
+ K +E K +E +E+ + E+ +K +P+ SA + ++
Sbjct: 478 KVVVAADKAKEQELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVPKVVISAAKAKEQET 537
Query: 1262 ---HDLLKSQVQIAEEKLEGR---VAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDD---- 1311
++ K Q Q+ +E + A V TK+E +P ++ ++D
Sbjct: 538 RISEEITKKQKQVTQEAIRQETEITAASMVVVATAKSTKLETVPGAQEETTTQQDQMHLS 597
Query: 1312 ------KTTKT-----------IKEQP-----QPPCTAKPDQVEPGKEKTEKEDDKSDTS 1349
+T KT +KEQ + T K +QV+ +EK KE +K+ S
Sbjct: 598 YEKIMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKREQVQITQEKMRKEAEKTALS 657
Query: 1350 S 1350
+
Sbjct: 658 T 658
Score = 49.3 bits (116), Expect = 1e-04
Identities = 259/1418 (18%), Positives = 464/1418 (32%), Gaps = 225/1418 (15%)
Query: 1428 ADEKSEKKT--QPHEVSPEQ-------PKDQEKTQSLSETLEITISEEEIKESQEERKDT 1478
A +K KK +P E++P + P E ++++ EE+K RK
Sbjct: 8988 AVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKE 9047
Query: 1479 FKKDSQQDIPSSKD-HKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSS 1537
+K+ + + HKEK F++ EPYD +E +E P +
Sbjct: 9048 VQKEKEAVYEKKQAVHKEKRVFIESF---EEPYDELEVEPYTEPFEQPYYEEPDEDYEEI 9104
Query: 1538 SDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTES-QKKEE 1596
E K+E + EEDF Q + G E+ E + + I E ++ E
Sbjct: 9105 KVEAKKEVHEEW--EEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHE 9162
Query: 1597 TKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEEL 1656
K K+ K + + E + +E+ + PE+ + + S
Sbjct: 9163 RKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTP 9222
Query: 1657 VVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEG 1716
V + + IE+ S++K ++F E E+ PE +
Sbjct: 9223 V--------QEEVIEVKVPAVHTKKMVISEEK--MFFASHTEEEVSVTV--PEVQKEIVT 9270
Query: 1717 SSSLHASSFTPGTSPTSVSSLDEDSDSS-----PSHKKGESKQQRKARHRPHGPLLPTIE 1771
+H + P V L E P KK E P P +P +
Sbjct: 9271 EEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVE----------PPAPKVPEVP 9320
Query: 1772 DSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLS 1831
++ + EE++ + +K+ + + K ++K + +++E PP+ +
Sbjct: 9321 ----KKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKE---APPAKVP 9373
Query: 1832 PIEDASPTEE-LRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAV 1890
++ TEE + + EE + E + PE + P K EV K+P
Sbjct: 9374 EVQKGVVTEEKITIVTQREESPPPAVPEIPK--KKVPEERKPVPRKEEEVPPPPKVPALP 9431
Query: 1891 SLYSPTDEQSI----MQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAANERDEVF----- 1941
P ++ ++ +K +A S + + EE + +F A +R EV
Sbjct: 9432 KKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSF-AVPQRVEVTRHEVS 9490
Query: 1942 -EKEPLYG----GMLIEDYIYESLVEDTYNGSVDGSLLTRQEE----------------- 1979
E+E Y G+ I Y E E+ + ++ EE
Sbjct: 9491 AEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAE 9550
Query: 1980 --ENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIP 2037
E Q+K K ++ +I E P K+ + K+ + + + VP+++ V +
Sbjct: 9551 PAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPE 9610
Query: 2038 ESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQ----MQLTPGSSPTQAPIGEDMTE 2093
E + V + + + L A + Q+ + +T +P +A + E+
Sbjct: 9611 EPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKR 9670
Query: 2094 STMDF---------DRMPDASLTS---------------------SVLSGASLTDSTSSA 2123
+ + + P A +T + + + +
Sbjct: 9671 AVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAY 9730
Query: 2124 TLSIPDVKITQHFSTEEIEDEYVTDY-----TREIQEIIAHESLILTYSEPSESATSVPP 2178
TL V + + EE E+ ++ T E + +E E E + P
Sbjct: 9731 TLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPE 9790
Query: 2179 SDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIID 2238
P V T + P L PV + K + P + +
Sbjct: 9791 KPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPP---------PPKVPE 9841
Query: 2239 YP-----EEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDL 2293
P E+I +S+ + A + + + + E VP P VA V
Sbjct: 9842 EPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRV---VAEEKVPVPRKEVAPPVRVPE 9898
Query: 2294 LISEKDPVKKAKKETGNGIILEVLEAY--RDKKELEAERTKSSLSETVFDHPPSSVIALP 2351
+ E +P + A +E ++ +E Y +++E E + E V P V +P
Sbjct: 9899 VPKELEPEEVAFEEE----VVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVP 9954
Query: 2352 MKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP 2411
K ++KP + +P P+ + I + PPP
Sbjct: 9955 RKPVPE-----------EKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAK 10003
Query: 2412 PPPPPPPPPP----PPP-------PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460
P P P P P P PP P PK + P+KK+ V +P P
Sbjct: 10004 VPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPV-PEKKVPVPAPKKVEAPPAKVPE 10062
Query: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPE--------------PS 2506
+ PV + PP VP K +P + E P
Sbjct: 10063 VPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPE 10122
Query: 2507 KPPIAP--KPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT---------LNLVTSADYKLP 2555
+ + P + V+P+ + +I P+ + ++ K+P
Sbjct: 10123 EEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVP 10182
Query: 2556 SPTSPLSPHSNKSSPRFSKSLTETYVVITLPSE------PGTPTDSSASQAITSWP---- 2605
P +P+ P K +TE VVI E P P + I
Sbjct: 10183 VP-APV--------PEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVL 10233
Query: 2606 ----LGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQA 2661
P ++ +S E + P + VE I A+ P P +A
Sbjct: 10234 PVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAV---PEAPTPVPKKVEA 10290
Query: 2662 APTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIP 2699
P V++ + E K V + AP + + +P
Sbjct: 10291 PPAKVSKKIPEE--KVPVPVQKKEAPPAKVPEVPKKVP 10326
Score = 48.9 bits (115), Expect = 1e-04
Identities = 128/579 (22%), Positives = 212/579 (36%), Gaps = 69/579 (11%)
Query: 990 PAKSIPVKKETKAPAAEKLEPKAEQAPT-----VKRTETEKKPPPIKDSKSLTAEPQKAV 1044
P P T+A A + +E + VK TE + S +AE + A
Sbjct: 32481 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 32540
Query: 1045 LPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQ--VCNLCGFNPTPHLTEIQ 1102
L EKS + +ST KT L P T E ++ C+ G P P +T ++
Sbjct: 32541 LE---EKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDG-EPVPTVTWLR 32596
Query: 1103 EWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQ 1162
+ L+ + ++ + V E+S K + + K +
Sbjct: 32597 KGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARV- 32655
Query: 1163 EVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEK---- 1218
TE +VK K P V + ++ + + KA + E KP P EK
Sbjct: 32656 ---TEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHL 32712
Query: 1219 --------------KLIPEEEKIRSEEKKPLLEEKKPT-PEDKKLLPEAKTSAPEEQKHD 1263
+ E K+ + +L K+ T +D K L E
Sbjct: 32713 PVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 32772
Query: 1264 LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQP 1323
+ ++ E +G + EG +T ++ + Q+ +K +K +
Sbjct: 32773 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM----GQAFKSIHEKVSKISE----- 32823
Query: 1324 PCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGIS----SSLGE-IP 1378
T K DQ T K + K+ S +P GL DT SSD ++ + GE P
Sbjct: 32824 --TKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRP 32881
Query: 1379 SLIPT-DEKDILKGLK------KDSFSQESSPSSPSDLAKLESTVL-SILEAQASTLADE 1430
+ I T D K I +G K K F E + SD TV S +S
Sbjct: 32882 TAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 32941
Query: 1431 KSEKKTQPHEVSPEQPKD---QEKTQSLSETLEITISEEEIK--ESQEERKDTFKKDSQQ 1485
K+ K T+ +VS ++ + Q+K E + + EEIK E++ + K K+++ +
Sbjct: 32942 KAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASK 33001
Query: 1486 DIPSSKDHK------EKSEFVDDITTRREPYDSVEESSE 1518
+ S + K EKS ++IT + + V +E
Sbjct: 33002 VLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAE 33040
Score = 41.2 bits (95), Expect = 0.027
Identities = 32/129 (24%), Positives = 45/129 (34%), Gaps = 29/129 (22%)
Query: 2411 PPPPPPPPPPPPPPPPLPPPTS-----PKPTILPKKKLTVASPVTTATPLFDAVTTLETT 2465
P P PPPP P +P T P+PT +P+ K + P P
Sbjct: 10975 PAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP----------- 11023
Query: 2466 AVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVF------THRPEPSKPPIAPKPVIPQL 2519
P + T PPPV P+P+ I + + P + PK I +
Sbjct: 11024 -------KPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGV 11076
Query: 2520 PTTTQKPTD 2528
P T P +
Sbjct: 11077 PKKTPSPIE 11085
Score = 39.3 bits (90), Expect = 0.10
Identities = 53/233 (22%), Positives = 89/233 (38%), Gaps = 33/233 (14%)
Query: 3505 DKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEII---KHISAPEKTYK 3561
+KT + + V V E+S + P RTP ++ KV + K + + EK +
Sbjct: 9190 EKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMF- 9248
Query: 3562 GGSLGCQTEADSDTQSPQYLSATSPPKDKKRPT--PLEIGYSSHLRADSTVQLAPSPPKS 3619
TE + +S T P K+ T + + S + V P P
Sbjct: 9249 ---FASHTEEE--------VSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAP 9297
Query: 3620 PKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSM 3679
+V PI A + VP +KP+P++ P P K P A PK ++ ++ +
Sbjct: 9298 EEVAPVPIPKKVEPPAPKVPEVP-KKPVPEEKKPV----PVPKKEPAAPPKVPEVPKKPV 9352
Query: 3680 SDPKPLSPTADESSRAPFQYTE---GYTTKGSQTMTSSGAQKKVKRTLPNPPP 3729
+ K P A + P + E G T+ T+ + + +PPP
Sbjct: 9353 PEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREE--------SPPP 9397
Score = 37.4 bits (85), Expect = 0.39
Identities = 73/331 (22%), Positives = 137/331 (41%), Gaps = 32/331 (9%)
Query: 1826 PPSNLSPIEDASPT-EELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKV- 1883
PP PI PT EE + + E+ + + + + + + P+ E++P + I V+K
Sbjct: 8958 PPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPK--EMTPREEI-VKKPP 9014
Query: 1884 -------YKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYE--EMMHKTHKYKAFPAA 1934
K P + + S +E IM ++ K E +YE + +HK K +
Sbjct: 9015 PPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHK-EKRVFIESF 9073
Query: 1935 NERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGF---MQQKGREQ 1991
E + E EP Y + Y YE ED V+ +E E F + RE+
Sbjct: 9074 EEPYDELEVEP-YTEPFEQPY-YEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREE 9131
Query: 1992 KIRLSEQIYEDPMQ--KITDLQKEFYELESLHSVVPQEDIVSSSFIIPESHEIVDLGTMV 2049
E+ +E+ Q ++ +QKE YE ES VP + + P +++ ++
Sbjct: 9132 GYDEGEEEWEEAYQEREVIQVQKEVYE-ESHERKVPAKVPEKKA---PPPPKVIK-KPVI 9186
Query: 2050 TSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSS 2109
E+ + ++ + + ++ P P++ P+ E++ E + ++
Sbjct: 9187 EKIEKTSRRMEEEKVQVTKVPEVSKKIVP-QKPSRTPVQEEVIEVKVPAVHTKKMVISEE 9245
Query: 2110 VLSGASLTDSTSSATLSIPDVKITQHFSTEE 2140
+ AS T+ S T +P+V+ + TEE
Sbjct: 9246 KMFFASHTEEEVSVT--VPEVQ--KEIVTEE 9272
Score = 37.4 bits (85), Expect = 0.39
Identities = 73/354 (20%), Positives = 143/354 (40%), Gaps = 52/354 (14%)
Query: 1737 LDEDSDSSPSHKKGESKQQRKARHRPHGPL---LPTIEDSSEEEELREEEELLKEQEKQR 1793
+ E+ +P KK E+ + + R P+ LP E+ EEE+ EEE+L E+E+
Sbjct: 10068 IPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVL 10127
Query: 1794 EIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSN--LSPIEDASPTEELRQAAEMEEL 1851
E+++ ++ +++E+ E + PP + E+ P EE+ + +
Sbjct: 10128 P-EEEEVLPEEEEVLPEEEEIPP----EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVP 10182
Query: 1852 HRSSCSEYSPSIESD----PEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGS 1907
+ E + P+ E P K+ EV K + +++ I+ KE
Sbjct: 10183 VPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVE-----------EKRIILPKEEE 10231
Query: 1908 QKALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNG 1967
++ EE EE + + + P+ E +EV + + I +++ E
Sbjct: 10232 VLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPR-------VPEVIKKAVPE----- 10279
Query: 1968 SVDGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESL---HSVV 2024
+ + E + +K E+K+ + Q E P K+ ++ K+ E + L V
Sbjct: 10280 -APTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAV 10338
Query: 2025 PQ-------EDIVSSSF----IIPESHEIVDLGTMVTSTEEERKLLDADAAYEE 2067
P E+ VS +F ++ E E+ + V EE + + + +EE
Sbjct: 10339 PPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEE 10392
Score = 37.4 bits (85), Expect = 0.39
Identities = 97/459 (21%), Positives = 171/459 (37%), Gaps = 101/459 (22%)
Query: 1158 KKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEE 1217
KKQE + K E E+ + +++ +TL M +I + + +K +A+ L KP
Sbjct: 31891 KKQEFKSKEEHERHVQKQIDKTLRMAEILSGTESVPLTQVAKEALREAAVLY--KPAVST 31948
Query: 1218 KKLIPEEEKIRSEEKKPLLEEKKP--TPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEK 1275
K + E ++ EEKK + + P PE +K +T+ E+Q+ +K V +++ K
Sbjct: 31949 KT-VKGEFRLEIEEKKEERKLRMPYDVPEPRKY---KQTTIEEDQR---IKQFVPMSDMK 32001
Query: 1276 LEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTT-KTIKEQPQPPCTAKPDQVEP 1334
++ + Q +M G Q PK + + P P T DQ P
Sbjct: 32002 WYKKI---------RDQYEMPGKLDRVVQKRPKRIRLSRWEQFYVMPLPRIT---DQYRP 32049
Query: 1335 GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPS---LIPTDEKDILKG 1391
+ D + + ++P D Y SLG+I L+P D+ +K
Sbjct: 32050 KWRIPKLSQDDLEIVRPARRRTPSPDYDFYYRPR--RRSLGDISDEELLLPIDDYLAMKR 32107
Query: 1392 LKKDSFSQE--------SSP---------------SSPSDLAKLESTVLSI--------L 1420
+++ E +SP SSP K+E T
Sbjct: 32108 TEEERLRLEEELELGFSASPPSRSPPHFELSSLRYSSPQAHVKVEETRKDFRYSTYHIPT 32167
Query: 1421 EAQASTLADEKSEKKTQPHEVSPEQPK-------DQEKTQSLSETLEITISEEEIKESQE 1473
+A+AST E E+ Q P+Q + D+E + ++ T ++ + E+ +
Sbjct: 32168 KAEASTSYAELRERHAQAAYRQPKQRQRIMAEREDEELLRPVTTTQHLSEYKSELDFMSK 32227
Query: 1474 ERKDTFKKDSQQDIPSSKDHKEKSEFVDD------------------------------- 1502
E K K Q+++ + +E+ E
Sbjct: 32228 EEKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVS 32287
Query: 1503 --ITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSD 1539
I +R +P + E+ +E SP P+R R S SS+
Sbjct: 32288 ELIRSRPQPAEEYEDDTE-RRSPTPERTRPRSPSPVSSE 32325
Score = 37.0 bits (84), Expect = 0.51
Identities = 72/370 (19%), Positives = 119/370 (32%), Gaps = 30/370 (8%)
Query: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP 2430
KP P + +P P+ + PPP P P P P +PP
Sbjct: 9565 KPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPK 9624
Query: 2431 TSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLR-----SNGLPVTRICTTAP-- 2483
LP K +T + AVT E R +P ++ P
Sbjct: 9625 VIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKR 9684
Query: 2484 -PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSM 2542
P K + +V + P P+P I ++ +K + +S+
Sbjct: 9685 EEEPPAKVTEFRKRVVKEEKVSIEAPKREPQP-IKEVTIMEEKERAYTLEEEAVSVQREE 9743
Query: 2543 TLNLVTSADYKLPSPTSPLSPHS--NKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQA 2600
DYK P + + R + E IT P +P P +
Sbjct: 9744 EYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKP-IPVKPVPEEP 9802
Query: 2601 ITSWPLGSPSKDLVSVEPVFSVVPPV------TAVEIPISSEQTF--YISGALQTFSATP 2652
+ + P P+K L P V P+ ++P ++ F I ++
Sbjct: 9803 VPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQ 9862
Query: 2653 VTAPSS-FQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDN---I 2708
VT P++ P V V + EV AP V + + + PE +A +
Sbjct: 9863 VTEPAAKVPMKPKRVVAEEKVPVPRKEV------APPVRVPEVPKELEPEEVAFEEEVVT 9916
Query: 2709 HLEKPQYKED 2718
H+E+ +E+
Sbjct: 9917 HVEEYLVEEE 9926
Score = 37.0 bits (84), Expect = 0.51
Identities = 39/185 (21%), Positives = 76/185 (41%), Gaps = 9/185 (4%)
Query: 1697 PELEMESLT-DSPEDRSRGEGSSS--LHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESK 1753
P E+ SL SP+ + E + +++ P + S S + + + + +
Sbjct: 32133 PHFELSSLRYSSPQAHVKVEETRKDFRYSTYHIPTKAEASTSYAELRERHAQAAYRQPKQ 32192
Query: 1754 QQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDE 1813
+QR R LL + + E + E + + ++EK R+ ++QR+ + +++ E
Sbjct: 32193 RQRIMAEREDEELLRPVTTTQHLSEYKSELDFMSKEEKSRKKSRRQREVTEITEIEEEYE 32252
Query: 1814 LRAQRRRERPKTPPSNLSPIEDASPT--EELRQAAEMEELHRSSCSEYSPSIESDPEGFE 1871
+ +RE + L SPT E +R +E+ EY E D E
Sbjct: 32253 ISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSELIRSRPQPAEEY----EDDTERRS 32308
Query: 1872 ISPEK 1876
+PE+
Sbjct: 32309 PTPER 32313
Score = 35.8 bits (81), Expect = 1.1
Identities = 42/177 (23%), Positives = 75/177 (42%), Gaps = 14/177 (7%)
Query: 2708 IHLEKPQYKEDGKLQLVGDVIDLRTVP--KVEVKTTDKCIDLSASTMDVKR-QITANEVY 2764
I ++K Y+E + ++ V + + P KV K + I+ ++ M+ ++ Q+T
Sbjct: 9150 IQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEV 9209
Query: 2765 GKQI-------SAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAE 2817
K+I + VQ +I + V + + ++ E + F + T T E V E
Sbjct: 9210 SKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPE--VQKE 9267
Query: 2818 HAMTTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINL--SLGTPAHAVTLAITKPV 2872
+ + SK EPP ++P P E AP+ + + PA V KPV
Sbjct: 9268 IVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPV 9324
Score = 34.7 bits (78), Expect = 2.5
Identities = 26/103 (25%), Positives = 39/103 (37%), Gaps = 12/103 (11%)
Query: 481 PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS 540
P + P PP + S PPS + Q P P + SP + P+ P +
Sbjct: 250 PHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRS--- 306
Query: 541 AQQPSPAKPSAQQSTKPVSQTGSG---KPLQPPTVSPSAKQPP 580
P+A+ ST P+ S + Q TV+ + PP
Sbjct: 307 ------VSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPP 343
Score = 34.3 bits (77), Expect = 3.3
Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 11/144 (7%)
Query: 827 DSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAG 886
+ KI +H S + + +D ++ P K ++ PKP ++ SPTPP A
Sbjct: 222 EKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSR-----SPTPPS---IAA 273
Query: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIF---SQAS 943
+ QQSP P S ++ + T +P + T + + + +QAS
Sbjct: 274 KAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQAS 333
Query: 944 NLISTAGQPGPHSQSGPGAPMKQA 967
+ + P P Q G A +A
Sbjct: 334 TVATGPEVPPPWKQEGYVASSSEA 357
Score = 34.3 bits (77), Expect = 3.3
Identities = 37/175 (21%), Positives = 52/175 (29%), Gaps = 54/175 (30%)
Query: 2368 GQEKPASQLPSGSPS----------VSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP-- 2415
G++K LP P + P + P L+ +P P PPPP P
Sbjct: 10928 GEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVE 10987
Query: 2416 ---------------------------PPPPPPPPPPP-------LPPPTSPKPTILPKK 2441
P P P P P P PPP P+PT
Sbjct: 10988 EVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPT----- 11042
Query: 2442 KLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSG 2496
+A+PVT A + G P+ + P P+ + + G
Sbjct: 11043 --PIAAPVTVPVVGKKAEAKAPKEEAAKPKG-PIKGVPKKTPSPIEAERRKLRPG 11094
Score = 33.9 bits (76), Expect = 4.3
Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 16/104 (15%)
Query: 480 PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP----PQQPGPAKPSPQQPGSTKPPSQQPG 535
PP P P P P A PP + P PP P KP P++ TK ++
Sbjct: 8934 PPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKK-- 8991
Query: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP 579
AK +P P + KP PPT AK P
Sbjct: 8992 DAKKVVAKPKEMTPREEIVKKP----------PPPTTLIPAKAP 9025
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 150 bits (380), Expect = 2e-35
Identities = 225/967 (23%), Positives = 330/967 (34%), Gaps = 212/967 (21%)
Query: 227 RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
RD + ++ +++ P + +PPG+ +P P TP +P ++A
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 287 DIVRGESVKPSLP---------SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG 337
+ G ++ S P + S+ P +P + P + + PGP P + SG
Sbjct: 63 GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
Query: 338 LTK--PLAQQ------------------------------------PGTVKPPV----QP 355
T+ PL Q+ PGT P + +
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
Query: 356 PGT------TKPPAQPLGPAKPPAQQTGS-EKPSSEQPGPKALAQP-------------- 394
GT P A+P P + P + S + S+ +P P A +P
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 395 --------------PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGP-TKT 439
P TP P++P + + +P P + A A GP + +
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
Query: 440 PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS---------QLPGPAKPPPQQ--PGPAK 488
P+ P P A+ P +A T PPS P P+ PP Q P P
Sbjct: 303 PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362
Query: 489 PPPQQ--PGSAKPPSQQPGS--TKPPPQQP----GPAKPSPQQPGSTKPPSQQPGSAKPS 540
PP Q P PP Q P S T PP Q P P+ +P P + P+
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422
Query: 541 AQ--------QPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ---------- 582
Q P + S ++P S PLQ P P++ PP Q
Sbjct: 423 LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS--PPLQTSLSPAVSPL 480
Query: 583 GLPKTICPLCNTTELLLHVPE---KANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLN 639
P TI PL + L H P+ + E Q+++ P LT
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT-------- 532
Query: 640 CQMKRALGGDLAPVPSSPQPKLKT--APVTTTSAVSKSSPQP----QQTSPKKDAAPKQD 693
L +PS P L+T AP+TT + P P SP P+
Sbjct: 533 --------PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584
Query: 694 LSKAPEPKKPPPLVKQPTLHGSPSAK----AKQPPEA-DSLSKPAPPKEPSVPSEQDKAP 748
S A P + PP + P L G PS A PP+A L+ P PS P+ +P
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644
Query: 749 VADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQS--- 805
+A P+ P + V A P PS VQ+ +PP+ + PSQ+
Sbjct: 645 LATPSPQAPNAL-----AVHLLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPPSQAPPS 698
Query: 806 -------FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKA 858
PP+ P A P P + + + P QV P P
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP---------LQVPPSPPASPPMSP 749
Query: 859 QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKS 918
+P P P+ P P P A + +P P PQ AP +
Sbjct: 750 SA--TPPPRVPPLLAAPPLQVPPSPPASLPM-SPLAKPPPQ---------------APPA 791
Query: 919 QPTTPQETVTGKLFGF-GASIFSQASNL-ISTAGQPGPHSQSGPGAPMKQA-PAPSQPPT 975
T P + + F G + FS +++L +S P P + AP+ Q P+P PT
Sbjct: 792 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 851
Query: 976 SQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKS 1035
Q P + PP P V A L P P+ + T P S S
Sbjct: 852 LQAP-----RRPPTPGPDTSVSGPRLTLA---LAPGPPPPPSRSPSSTLSGPDLAGHSSS 903
Query: 1036 LTAEPQK 1042
T+ P++
Sbjct: 904 ATSTPEE 910
Score = 145 bits (365), Expect = 1e-33
Identities = 266/1055 (25%), Positives = 372/1055 (35%), Gaps = 164/1055 (15%)
Query: 28 GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQEL 87
G+ P PA + L R+ +A RA G+ ++P +A + R
Sbjct: 31 GSPRPPPPVTPAALRV-LGAAGAVGRKPLA---ERAGGIGGATIPESAPRAGPT-RSAGT 85
Query: 88 DSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEE 147
S +P + RPP GR + +K+ + S PGR+ T + + L+
Sbjct: 86 SSRNP---ASRPPASGRGERAPPAKNTSPGPVSS----PGRASGT-TRPGPLGQKGLRIS 137
Query: 148 HKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEET-TKKQKVVQKEQGKPEGI 206
+ ++ G +E SA+S+ + D + + ++ + E G P
Sbjct: 138 AEETVARGKATEAPKRSALSAGARR----DTSGPTPGTPSPAMARRSRAAGTEVGLPR-- 191
Query: 207 IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQ 266
P P + + P P + + S+ +P + P G +Q P
Sbjct: 192 ---------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 267 TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
+ A PL A + RG P+ PS KP Q +PP P +
Sbjct: 243 SSSAT-PLSSPA-----RSGPSARGTPRAPAHPSQPKPKGLQAL--RPPQVTP--PRKDA 292
Query: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT-------TKPPAQPLGPAKPPAQQTGSE 379
PA P S L P GT PV PP T PP+ PL P A + S
Sbjct: 293 APALGPLSSSPLATP--SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
Query: 380 KPSSEQ-PGPKAL--AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGP 436
PS + P P A +Q P TP Q P+ + P L P LQ+P P P
Sbjct: 351 PPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS-PSLQAP---PSP 406
Query: 437 TK-TPVQQPGPGKIPAQQA-------GPGKTSAQQTGPTKPPSQLPG----------PAK 478
+ +Q P QA P +T A T P++P S P PA
Sbjct: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS 466
Query: 479 PPPQQP-GPAKPP--------------------PQQPGSA--KPPSQQPGSTKPPPQQPG 515
PP Q PA P PQ P S+ PP + S PP Q
Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526
Query: 516 PAK---PSPQQPGSTKPPSQQPGSAK--------PSAQQPSPAKPSAQQSTKPVSQTGSG 564
PA P + S PP Q SA P P P + T P +T S
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSS 586
Query: 565 KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN 624
PP P+ PP QGLP PL + L P+ Q
Sbjct: 587 IATPPPQAPPALASPPLQGLPSP--PL---SPLATPPPQAPPXLALPPLQAP-------- 633
Query: 625 PNPHLTEVKEWLCL-NCQMKRALGGDLAPVPSSPQPKLKT-APVTTTSA--VSKSSPQPQ 680
P+P + L + Q AL L P SP P AP + ++ VS S+ P
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
Query: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA-DSLSKPAPPKEPS 739
Q P A P L P P PP+ SPS A PP+A L+ P PS
Sbjct: 694 QAPPSLAAPP---LQVPPSPPASPPM--------SPS--ATPPPQAPPPLAAPPLQVPPS 740
Query: 740 VPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEK-TTPPLKTD 798
P+ +P A P+ P ++ V S + P P +K QA TPPL+
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800
Query: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKA 858
+ P+ SFP +PF S + P S P + QV P P +
Sbjct: 801 PSPPA-SFPGQ----APF-SPSASLPMSPLATPPPQAPPVLAAPLLQVPP-----SPPAS 849
Query: 859 QTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKS 918
T +P+ P P S + GPR T P P P P +S +L+ + S
Sbjct: 850 PTLQAPRRPPTPGPDTSVS--GPRLTLA-LAPGP---PPPPSRSPSSTLSGPDLAGHSSS 903
Query: 919 QPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP---PT 975
+TP+E G + S + A P S+ GP P+ AP P P
Sbjct: 904 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR-GPAPPLAFRGAPGAPLPWPP 962
Query: 976 SQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEP 1010
+ GP + G + E+ PA L+P
Sbjct: 963 ATGPGSADGLCTIYETEG----PESATPAPGALDP 993
Score = 142 bits (359), Expect = 7e-33
Identities = 229/915 (25%), Positives = 303/915 (33%), Gaps = 150/915 (16%)
Query: 16 LAAAAAAGGGASGAGSPSHTAIPA----GMEADLSQLSEEERRQIAAVMSRAQGLPKGSV 71
+A + A G G P+ +A P G +S SE + + R G
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR--- 128
PA+ S + P G P P P+QP K + R Q P R
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP---KPKGLQALRPPQVTPPRKDA 292
Query: 129 SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAV---SSVVNKFNPFDLISDSEAS 185
+P+ L S T K+ +P + L A S + P S S
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP 352
Query: 186 QEETTKKQKVVQKEQGKPEGIIKPPLQQQPP-KPIPKQQGPGR---DPLQQDGTPKSISS 241
+T Q P + PP+Q P + IP Q P LQ +P ++SS
Sbjct: 353 SLQTLPSPPATPPSQAPPS-MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411
Query: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301
Q P T Q H+ L + P+ QA + +P+ P
Sbjct: 412 LQATTSLGSP------------TLQATHSFLTMS-----PRQTQASLTSPS--RPASTPP 452
Query: 302 SKPPIQQPT--PGKPPAQ----------------QPGHEKSQPGPAKPPAQPSGLTKPLA 343
PP+Q P P PP Q P S P A S L P
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512
Query: 344 QQPGTVKPP---VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ------PGPKALAQP 394
+ ++ PP P T PP + L PP QT S ++ P P L P
Sbjct: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP 572
Query: 395 PGVGKTPAQQPGP--AKPPTQQVGTPKPLAQQP--GLQSPAKAPGPTKTPVQQPGPGKIP 450
P TP + A PP Q P LA P GL SP +P T P Q P +P
Sbjct: 573 PSPLTTPPPETPSSIATPPPQ---APPALASPPLQGLPSPPLSPLATPPP-QAPPXLALP 628
Query: 451 AQQAGPGKTSAQQTGPTKPPSQ----------LPGPAKPPPQQP--GPAKPPPQQP--GS 496
QA P ++ P PS L P PPP P P PP P S
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688
Query: 497 AKPPSQQPGSTKPPPQQPGPAKPS--PQQPGSTKPPSQQPGSAKPSAQQPS--PAKPSAQ 552
A PPSQ P S PP Q P+ P+ P P +T PP P A P Q P PA P
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748
Query: 553 QSTKP---VSQTGSGKPLQPPT-------VSPSAKQPPSQGLPKTICPLCNTTELLLHVP 602
S P V + PLQ P +SP AK PP PL P
Sbjct: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP 808
Query: 603 EKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662
+A F+ + + P P Q L L VP SP
Sbjct: 809 GQAPFSPSASLPMSPLA----TPPP-------------QAPPVLAAPLLQVPPSP----- 846
Query: 663 TAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP-----PLVKQPTLHGSPS 717
P + T + P P + + P+ L+ AP P PP + P L G S
Sbjct: 847 --PASPTLQAPRRPPTPGPDT--SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902
Query: 718 AKAKQP---------PEADSLSKPAPPKE-----PSVPSEQDKAPVA-DDKPKQPKMVKP 762
+ P PE + + P P E P+ S P+A P P P
Sbjct: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962
Query: 763 TTDLVSSSSATT--KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK- 819
T S+ T + + P S + P T K + SP ++
Sbjct: 963 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 1022
Query: 820 -AIPRPASDSKIISH 833
+P A + ++ H
Sbjct: 1023 GELPLGALQASVVQH 1037
Score = 107 bits (266), Expect = 4e-22
Identities = 201/850 (23%), Positives = 288/850 (33%), Gaps = 170/850 (20%)
Query: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP---AQQTGSEKPSSEQPGPKALAQPPGV 397
P A+ PG + P +PPG+ +PP P+ PA A KP +E+ G G+
Sbjct: 17 PAARAPGLLTP--RPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAG--------GI 65
Query: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
G + P PT+ GT ++ P + PA G P + PG + + PG
Sbjct: 66 GGATIPESAPRAGPTRSAGTS---SRNPASRPPASGRGERAPPAKNTSPGPV----SSPG 118
Query: 458 KTSAQQTGPTKP-PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516
+ S G T+P P G + K SA + ++ P P P P
Sbjct: 119 RAS----GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
Query: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
A + T+ +P PSA+ P P ++S S+ + +P SP+A
Sbjct: 175 AMARRSRAAGTEVGLPRPA---PSAR-PRPPTEGPRKSVSSASEHSTTEP------SPAA 224
Query: 577 KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636
++ PS G L P + ++ T + S P+
Sbjct: 225 RRRPSAGGG-------------LQRPASRSLSSSA---TPLSSPARSGPS---------- 258
Query: 637 CLNCQMKRALGGDLAPV-PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS 695
A G AP PS P+PK + P PQ T P+KDAAP
Sbjct: 259 --------ARGTPRAPAHPSQPKPK----------GLQALRP-PQVTPPRKDAAPALG-- 297
Query: 696 KAPEPKKPPPLVKQPTLHGSPSA-KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
PL P SPS KA+ P D+ + P P P P P+A P
Sbjct: 298 ---------PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
Query: 755 KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS 814
P P+ + S AT P S TTPP++ A PS P +
Sbjct: 349 SAP----PSLQTLPSPPATPPSQAPPS--------MTTPPMQ---APPSLQTIPPIQVPH 393
Query: 815 PFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKM-------SPKPD 867
S ++ P S + S +S Q P++ Q + S PD
Sbjct: 394 SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453
Query: 868 AKPM--PKGSPTPPGPRPTAGQTVPTPQQSP-------------KPQEQSRRFSLNLGSI 912
+ P+ P P P P T+ +P SP Q+ SL + +
Sbjct: 454 SPPLQAPLSLPASP-PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512
Query: 913 TD----APKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP--GPHSQSGPGAPMKQ 966
AP S T P T L ++ S A + TA P PH ++ P
Sbjct: 513 ETQSSLAPPSLQTPPASLTTPPL----ENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
Query: 967 APAPSQPPTSQGP--PKSTGQAPP--APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022
AP P T+ P P S PP PA + P + +P L QAP
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL- 627
Query: 1023 TEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTEC 1082
PP++ S A P + L T P P++ L L PP+
Sbjct: 628 -----PPLQAPPSPPASPPLSPLAT-----PSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677
Query: 1083 KNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTE 1142
+ TP +Q S ++ P P+ P SP P
Sbjct: 678 SPPASPPVSPSATP-------------PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724
Query: 1143 SSSQKTAVPP 1152
+ A PP
Sbjct: 725 QAPPPLAAPP 734
Score = 82.8 bits (203), Expect = 8e-15
Identities = 160/700 (22%), Positives = 239/700 (34%), Gaps = 92/700 (13%)
Query: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP--SAQQPSPAKPSAQQ-- 553
K + G+ P P +P+ PGS +PP +A A KP A++
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
Query: 554 ----STKPVSQTGSGKPLQPPTVSPS-AKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
+T P S +G T S + A +PP+ G + P NT+ + P +A+
Sbjct: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 609 T----------CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ 658
T + TV TE + L+ +R G P P +P
Sbjct: 124 TRPGPLGQKGLRISAEETVA-------RGKATEAPKRSALSAGARRDTSG---PTPGTPS 173
Query: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
P + + V P P P++ +S A E P P PSA
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP---SPAARRRPSA 230
Query: 719 -KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD 777
Q P + SLS A P + S P A P+ P P+ A P
Sbjct: 231 GGGLQRPASRSLSSSATP----LSSPARSGPSARGTPRAP--AHPSQPKPKGLQALRPPQ 284
Query: 778 IPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEK---VSPFDSKAIPRPAS--DSKIIS 832
+ + + P L S+ P + P+G K V P D+ A P PA+ S ++
Sbjct: 285 V------TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338
Query: 833 HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP---TPPGPRPTAGQTV 889
P P + P QT P P A P + P TPP P + QT+
Sbjct: 339 TPLPLAP----------PSPSAPPSLQT--LPSPPATPPSQAPPSMTTPPMQAPPSLQTI 386
Query: 890 P---TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI 946
P P P Q+ L L S+ T Q T F Q +
Sbjct: 387 PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT-----HSFLTMSPRQTQASL 441
Query: 947 STAGQPGPHSQSGPGAPMKQAP--APSQPP--TSQGPPKSTGQAP----PAPAKSIPVKK 998
++ +P + + P +P QAP P+ PP TS P S +P P A S
Sbjct: 442 TSPSRP---ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH 498
Query: 999 ETKAPAAEKLEPKAE-----QAPTVKRTETEKKPPPIKDSKSLTAEP---QKAVLPTKLE 1050
+AP + + P E P+++ PP+++ SL P A L T
Sbjct: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL 558
Query: 1051 KSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQ 1110
++P + CPL + + P ++ Q P L
Sbjct: 559 ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP 618
Query: 1111 TQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAV 1150
Q L ++ P P+ P SP+ P+ + AV
Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 658
Score = 77.8 bits (190), Expect = 3e-13
Identities = 106/362 (29%), Positives = 134/362 (37%), Gaps = 49/362 (13%)
Query: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP-------PPPPPPP 2420
G ++PAS+ S S + S PA+ P R + P P P P PP PP
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGT----PRAPAHPSQPKPKGLQALRPPQVTPP 288
Query: 2421 PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT 2480
P P S P P T A PV P +A T L T LP +
Sbjct: 289 RKDAAPALGPLSSSPLATPSPSGTKARPV---PPPDNAATPLPAT-------LPPSPPLA 338
Query: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPT--DIHPKPTGLSL 2538
T P PP PS+ PS P P P + P P P+ I P SL
Sbjct: 339 TPLPLAPPSPSAPPS---LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395
Query: 2539 TS-SMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEP-GTPTDSS 2596
TS S+ A L + TS SP + + S +T +T PS P TP DS
Sbjct: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
Query: 2597 ASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAP 2656
QA S P P + S+ P S P+SS T + AL + ++ AP
Sbjct: 456 PLQAPLSLPASPPLQ--TSLSPAVS----------PLSSPLTIHPLQALSSLASHSPQAP 503
Query: 2657 SSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPL-----ALDNIHLE 2711
S P TQ S A+ +T P L S++ P PL L HLE
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA----PPPLQTASAPLTTPHLE 559
Query: 2712 KP 2713
P
Sbjct: 560 TP 561
Score = 71.6 bits (174), Expect = 2e-11
Identities = 71/259 (27%), Positives = 96/259 (37%), Gaps = 25/259 (9%)
Query: 2335 LSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFF 2394
L + F PPS + P S S P SQ P PS+++ P + P
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSAT------PPSQAP---PSLAAPPLQVPPSP 710
Query: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454
+S + PPP PPP PP PP PP PP SP T P+ +A+P P
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770
Query: 2455 LFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFT----------HRPE 2504
A + A P + T +P P+S P F+ P
Sbjct: 771 SPPASLPMSPLAKPPPQAPPA--LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 828
Query: 2505 PSKPPIAPKPVIPQLPTTTQKPTDIHP-KPTGLSLTSSMTLNLVTSADYKLPSPTSPLSP 2563
P PP+ P++ P+ PT P +P +S++ +T A P P SP
Sbjct: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
Query: 2564 HSNKSSPRF---SKSLTET 2579
S S P S S T T
Sbjct: 889 SSTLSGPDLAGHSSSATST 907
Score = 63.9 bits (154), Expect = 4e-09
Identities = 95/376 (25%), Positives = 134/376 (35%), Gaps = 50/376 (13%)
Query: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPP----L 2427
P S P +PS S A+P P +++ + A PP PP P P PP P PP L
Sbjct: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357
Query: 2428 PPPTSPKPTILPKKKLT--------------------VASPVTTATPLFDAVTTLETTAV 2467
P P + P+ P T + SP A P A+++L+ T
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417
Query: 2468 LRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPT 2527
L S L T T P + PS RP + P P LP + T
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPS------RPASTPPDSPPLQAPLSLPASPPLQT 471
Query: 2528 DIHPKPTGLSLTSSMTLN-LVTSADYKLPSPTSPLS----PHSNKSSPRFSKSLTETYVV 2582
+ P + LS S +T++ L + SP +PLS P S SL
Sbjct: 472 SLSPAVSPLS--SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS 529
Query: 2583 ITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYIS 2642
+T P P+ + S PL +P + P P+ A P+++ S
Sbjct: 530 LTTPPLENLPSLAPPPLQTASAPLTTPHLE----TPPCPAPCPLQAPPSPLTTPPPETPS 585
Query: 2643 G-ALQTFSATPVTAPSSFQAAPTSVTQFLTT-------EVSKTEVSATRSTAPSVGLSSI 2694
A A P A Q P+ L T ++ + A S S LS +
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL 645
Query: 2695 SITIPPEPLALDNIHL 2710
+ P P AL +HL
Sbjct: 646 ATPSPQAPNAL-AVHL 660
Score = 61.2 bits (147), Expect = 3e-08
Identities = 91/376 (24%), Positives = 135/376 (35%), Gaps = 57/376 (15%)
Query: 2331 TKSSLSETVFDHPPSSVIALPMKE--------------QLSTTYFTSGETFGQ---EKPA 2373
T+SSL+ PP+S+ P++ L+T + + + P
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573
Query: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP--PP---------P 2422
S L + P S A P P + Q P PP P PPP PP P
Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP 633
Query: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTA------TPLFDAVTTLETTAVLRSNGLPVT 2476
P PP PP SP T P+ +A + A +P A + + + + P +
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
Query: 2477 RI--CTTAPP-PVPPKPSSIPSGLVFTHRPEPSKPPIAPKP--VIPQLPTTTQKPTDIHP 2531
+ APP VPP P + P P + PP+A P V P P + P
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753
Query: 2532 KPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGT 2591
P L ++ L + S L P SPL+ ++ P + T + LPS P +
Sbjct: 754 PPRVPPLLAAPPLQVPPSPPASL--PMSPLAKPPPQAPPALA-----TPPLQALPSPPAS 806
Query: 2592 ---PTDSSASQAITSWPLGSP--------SKDLVSVEPVFSVVPPVTAVEIPISSEQTFY 2640
S S ++ PL +P + L+ V P P + A P +
Sbjct: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866
Query: 2641 ISGALQTFSATPVTAP 2656
+SG T + P P
Sbjct: 867 VSGPRLTLALAPGPPP 882
Score = 59.7 bits (143), Expect = 7e-08
Identities = 109/471 (23%), Positives = 165/471 (35%), Gaps = 79/471 (16%)
Query: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSE--- 2337
P V ++++ L + P+ + + + L+A + +T++SL+
Sbjct: 387 PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446
Query: 2338 ---TVFDHPP-SSVIALPMKEQLSTTY------FTSGETFGQEKPASQLPSGSPS--VSS 2385
T D PP + ++LP L T+ +S T + S L S SP +SS
Sbjct: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS 506
Query: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPP--------PPP--------------PPPPPP 2423
L P +SS S Q PP PP PPP PP P
Sbjct: 507 LIMPPLE-TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565
Query: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
P PL P SP T P+ ++A+P A P A GLP +P
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPP---------ALASPPLQGLP-------SP 609
Query: 2484 P--PVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSS 2541
P P+ P P L P PP +P P+ P + Q P ++
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASP-PLSPLATPSPQAP-------------NA 655
Query: 2542 MTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLT------ETYVVITLPSEPGTPTDS 2595
+ ++L+ + PSP +P S +SP S S T + L P P
Sbjct: 656 LAVHLLQAPFSPPPSPPVQ-APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 714
Query: 2596 SASQAITSWPLGSP--SKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPV 2653
S + T P P + + V P PP++ P + LQ + P
Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774
Query: 2654 TAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLA 2704
+ P S A P + + ++ P S S ++P PLA
Sbjct: 775 SLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825
Score = 55.5 bits (132), Expect = 1e-06
Identities = 116/521 (22%), Positives = 172/521 (33%), Gaps = 97/521 (18%)
Query: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVA 2446
P P P S + P P P P PP P + + + T
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS--------EHSTTEP 220
Query: 2447 SPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-----PPVPPKPSS-IPSGLVFT 2500
SP P + L S+ P++ + P P P PS P GL
Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 280
Query: 2501 HRPEPSKPPIAPKPVIPQL---PTTTQKP--TDIHPKPTGLSLTSSMTLNLVTSADYKLP 2555
P+ + P P + L P T P T P P + + + L S P
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP 340
Query: 2556 SPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVS 2615
P +P SP + S + TLPS P TP S A ++T+ P+ +P
Sbjct: 341 LPLAPPSPSAPPS-------------LQTLPSPPATP-PSQAPPSMTTPPMQAP------ 380
Query: 2616 VEPVFSVVPPVTAVEIPIS----SEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLT 2671
P +PP +++P S S Q AL + AT + QA + FLT
Sbjct: 381 --PSLQTIPP---IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS----FLT 431
Query: 2672 TEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLR 2731
+T+ S T + P+ + PP D+ L+ P + L
Sbjct: 432 MSPRQTQASLTSPSRPA--------STPP-----DSPPLQAP--------------LSLP 464
Query: 2732 TVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLA 2791
P ++ + LS+ Q ++ + + I+ T S + P SL
Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
Query: 2792 TETVTFVTCTASASYTTGTESLVGAEHAMTT------------PLQLTTSKHAEPPYRIP 2839
T + T + L A +TT PLQ S PP P
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584
Query: 2840 SDQVFPIAREEAPINLS----LGTPAHAVTLAITKPVTVPP 2876
S P +AP L+ G P+ ++ T P PP
Sbjct: 585 SSIATP--PPQAPPALASPPLQGLPSPPLSPLATPPPQAPP 623
Score = 42.4 bits (98), Expect = 0.012
Identities = 45/154 (29%), Positives = 55/154 (35%), Gaps = 56/154 (36%)
Query: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSG--SPSVSSLPAKPR------PFF 2394
PPS +LPM KP Q P +P + +LP+ P PF
Sbjct: 769 PPSPPASLPMSPLA--------------KPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
Query: 2395 RSSSLDIS--AQPPPPPPP---------PPPPPPPP-------PPPPPP----------- 2425
S+SL +S A PPP PP PP PP P PP P P
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
Query: 2426 -----PLPPPTSPKPTILPKKKLTVASPVTTATP 2454
P PPP+ + L L S T+TP
Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 908
Score = 38.9 bits (89), Expect = 0.13
Identities = 42/160 (26%), Positives = 60/160 (37%), Gaps = 18/160 (11%)
Query: 3581 LSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAF 3640
L+ SP K RP P ++ L A L PSPP + + P++P SP
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPAT----LPPSPPLATPL---PLAPPSPSAPPSLQT 356
Query: 3641 VPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPK---PLSPTADESSRA-- 3695
+P P +P + P M P + S++ P P SP A S +A
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416
Query: 3696 -----PFQYTEGYTTKG-SQTMTSSGAQKKVKRTLPNPPP 3729
Q T + T QT S + + T P+ PP
Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP 456
Score = 37.7 bits (86), Expect = 0.30
Identities = 95/410 (23%), Positives = 131/410 (31%), Gaps = 118/410 (28%)
Query: 2402 SAQPPPPPPPPPPPPPPPPPPPPP---------------PLP------------------ 2428
+A+ P P PP P PPPP P PL
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 2429 ----------------PPTSPKPTILPKKKLTVASPV---------TTATPLFD---AVT 2460
PP S + P K T PV T PL ++
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
Query: 2461 TLETTAVLRSNGLPV-------TRICTTAPPPVPPKP-----SSIPSGLVFTHRPEPSKP 2508
ET A ++ P R T+ P P P P S V RP PS
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197
Query: 2509 PIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKS 2568
P P + ++ + + P P S+ L A L S +PLS S
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG-GLQRPASRSLSSSATPLS-----S 251
Query: 2569 SPRFSKSLTETYVVITLPSEPG------------TPTDSSASQA---ITSWPLGSPSKDL 2613
R S T PS+P TP A+ A ++S PL +PS
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG 311
Query: 2614 VSVEPV----------FSVVPPVTAVEIPIS-SEQTFYISGALQTFSATPVTAPSSFQAA 2662
PV + +PP + P+ + + +LQT + P T PS A
Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ---A 368
Query: 2663 PTSVTQFLTTEVSKTEVSATRSTAPSV----GLSSISITIPPEPLALDNI 2708
P S+T + + T P + L+S S+ PP PLAL ++
Sbjct: 369 PPSMT------TPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL 412
Score = 34.7 bits (78), Expect = 2.5
Identities = 31/127 (24%), Positives = 46/127 (36%), Gaps = 6/127 (4%)
Query: 3573 SDTQSPQYLSATSPPKDKKRPT---PLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISP 3629
S SP + +PP P PL++ S + P PP+ P +L +P
Sbjct: 709 SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP-PPRVPPLLAAPPLQ 767
Query: 3630 LSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTA 3689
+ P P KP P +P + P + +P S S P+SP A
Sbjct: 768 VPPSPPASLPMSPLAKPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 825
Query: 3690 DESSRAP 3696
+AP
Sbjct: 826 TPPPQAP 832
Score = 33.9 bits (76), Expect = 4.3
Identities = 48/168 (28%), Positives = 63/168 (37%), Gaps = 18/168 (10%)
Query: 3869 PPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTF 3928
PP QT PP +P +Q S P QAP S QT+ QV T P+
Sbjct: 351 PPSLQTLPS--PPATPPSQAPPSMTTPPMQAPPSL--------QTIPPIQVPHSLTSPSL 400
Query: 3929 QAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQKPRQTTLYL----EPKITSNYEVIRNQ 3984
QA + +Q T T S L + + PRQT L P T
Sbjct: 401 QAPPSPLALSSLQAT-TSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA 459
Query: 3985 PLMI---APVSTDNTFAVSHLGSKYNSLDLRIGLEERSSMASSPISSI 4029
PL + P+ T + AVS L S L+ S +P+SS+
Sbjct: 460 PLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL 507
Score = 33.9 bits (76), Expect = 4.3
Identities = 53/179 (29%), Positives = 76/179 (42%), Gaps = 24/179 (13%)
Query: 3517 AVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQ 3576
++QT+ I V ++ +PS++A +S+ + T GS Q T
Sbjct: 382 SLQTIPPIQVPH----SLTSPSLQAPPSPLA-----LSSLQATTSLGSPTLQATHSFLTM 432
Query: 3577 SPQYLSA--TSPPKDKKRPT---PLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLS 3631
SP+ A TSP + P PL+ S L A +Q + SP SP L SP++ +
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLS--LPASPPLQTSLSPAVSP--LSSPLT-IH 487
Query: 3632 PGKALES-AFVPYEKPLPDDISP----QKVLHPDMAKVPPASPKTAKMMQRSMSDPKPL 3685
P +AL S A + PL I P Q L P + PPAS T + P PL
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
Score = 33.9 bits (76), Expect = 4.3
Identities = 51/210 (24%), Positives = 75/210 (35%), Gaps = 20/210 (9%)
Query: 3500 SMTEADKTKPLSKVSSIAVQTVAEI---SVQTEPVGTIRTPSIRARVDAKVEIIKHISAP 3556
S+ PLS + ++T + + S+QT P ++ TP + ++ SAP
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA-SLTTPPLENLPSLAPPPLQTASAP 552
Query: 3557 EKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDK--------KRPTPLEIGYSSHLRADS 3608
T + C A Q+P T PP+ + P L L +
Sbjct: 553 LTTPHLETPPCP--APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610
Query: 3609 TVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPAS 3668
LA PP++P L P P P P P + V PP S
Sbjct: 611 LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670
Query: 3669 PKTAKMMQRSMSDP--KPLSPTADESSRAP 3696
P +Q S P P+SP+A S+AP
Sbjct: 671 PP----VQAPFSPPASPPVSPSATPPSQAP 696
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 145 bits (367), Expect = 8e-34
Identities = 387/1979 (19%), Positives = 704/1979 (35%), Gaps = 297/1979 (15%)
Query: 45 LSQLSEEERRQIAAVMSRAQGLPKGS----------VPPAAAESP---SMHRKQELDSSH 91
L++L+E++ ++ A + GS A E P S+ R+ S
Sbjct: 124 LAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSP 183
Query: 92 PPKQSGRPP--DPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHK 149
PKQ + D GR ++ S S + +S +K RS S ++ +S T K + K
Sbjct: 184 TPKQKKKKKKKDRGRRSE---SSSPRRERKKSSKKKKHRSESESKKRKHRSPTP-KSKRK 239
Query: 150 SSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKP 209
S S + S ++ D S S+ S+ ++ + K
Sbjct: 240 SKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSR---SRSRSAAAKTH-------TT 289
Query: 210 PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGT---------GKPIQG 260
L + P P ++G G P + GT + PE QP K
Sbjct: 290 ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATR 349
Query: 261 PTQTPQTDH------AKLPL--QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312
P+ +P+ A PL +R PQ + E V P PS + P + +P
Sbjct: 350 PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP--PSEASPT-RDRSPP 406
Query: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL------ 366
K P + P S+ P P QP+ +++ + P + KP P + + P
Sbjct: 407 KSPEKLPQSSSSESSPPSP--QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSH 464
Query: 367 GPAK-------PPAQQTG-SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTP 418
G AK P+++ G S P++ + G P G + ++ P + + Q
Sbjct: 465 GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR 524
Query: 419 KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK---PPSQLPG 475
Q+ G + PG +++ Q A++ S G ++ P +
Sbjct: 525 SRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRS 584
Query: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS-TKPPSQQP 534
++ P ++ ++ P ++ ++ P+++ S P + SP + S ++ P+++
Sbjct: 585 RSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRS 644
Query: 535 GSAKPS-------AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT 587
G ++ ++ +PA+ +S P ++G + P S + P +G ++
Sbjct: 645 GRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRS 704
Query: 588 ICPLCNTTELLLHVPEKANFNTCTECQT---TVCSLCGFNPNPHLTEVKEWLCLNCQMKR 644
+ + + +E + T N +P + + + ++ + R
Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSR----ISSRRSR 760
Query: 645 ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPK--- 701
+L SSP+ K K+ ++ ++S SSP P+Q K P++ S + +PK
Sbjct: 761 SL--------SSPRSKAKSR-LSLRRSLSGSSPCPKQ---KSQTPPRRSRSGSSQPKAKS 808
Query: 702 KPPPLVKQPTLHGSPSAKAKQPP-EADSLSKPAPPKEPSVPSEQDK--APVADDKPKQPK 758
+ PP + + P K+K P ++ S S P P + P Q +P A+++ P+
Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQ 868
Query: 759 M-----------VKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA--KPSQS 805
+K T S S ++ P + SS Q+ +++ P A P Q
Sbjct: 869 RRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQR 928
Query: 806 FPPTGEKVSP--FDSKAIPRPASD----SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ 859
SP S+ PR + S + S P G D K E P +
Sbjct: 929 SHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQS 988
Query: 860 TK--MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL--GSITDA 915
+SP P K + TPPGP + + SP PQE+S+ + GS++
Sbjct: 989 HSGSISPYPKVK-----AQTPPGPSLSGSK-------SPCPQEKSKDSLVQSCPGSLSLC 1036
Query: 916 PKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP---MKQAPAPSQ 972
+ +TP G S F +S + Q P +S +P + +PS
Sbjct: 1037 AGVKSSTPP----------GESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSL 1086
Query: 973 PPTSQGPPKSTGQAPPAPAKSI----PVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPP 1028
SQ PK +P + P++++ +A + K+ +P R +++
Sbjct: 1087 QSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPML-KSGMSPEQSRFQSDSSSY 1145
Query: 1029 PIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCN 1088
P DS SL + + +K + + P+ + PP
Sbjct: 1146 PTVDSNSLLGQSRLETAESKEKMALPPQEDA----------TASPPRQKD---------- 1185
Query: 1089 LCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAP-SGPKASPMPVPTESSSQK 1147
F+P P Q + S D + PP SG +SP E+ Q
Sbjct: 1186 --KFSPFP------------VQDRPESSLVFKDTLRTPPRERSGAGSSP-----ETKEQN 1226
Query: 1148 TAVPPQ------VKLVKKQEQ-------EVKTEAEKVILEKVKETLSMEKIPPM-VTTDQ 1193
+A+P +++V+K E+ + +E +++ + + +E+ P + +T DQ
Sbjct: 1227 SALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQ 1286
Query: 1194 KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKK----LL 1249
Q ++ LE + ++ P PE +++ + PL E +P + + L
Sbjct: 1287 SQSQASLEAVEVPSMASSWGGPH---FSPEHKELSNS---PLRENSFGSPLEFRNSGPLG 1340
Query: 1250 PEAKTSAPEEQKHDL-------LKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGT 1302
E T E K DL L++ + ++ R + + E + G+ S
Sbjct: 1341 TEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQ 1400
Query: 1303 PQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSD 1362
S P D +E+ +A +++ G +T +S +S + S +
Sbjct: 1401 SISSPVLDAVPRTPSRERSS---SASSPEMKDGLPRTPSRRSRSGSSPGLRDGSG---TP 1454
Query: 1363 TGYSSDGISSSLGEIPSL-----IPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVL 1417
+ +S G S + +IP D K L + + SPSSP K +
Sbjct: 1455 SRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQR 1514
Query: 1418 SILEAQASTLADEKSEKKT---QPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEE 1474
+++S D+K+ +T Q Q D + + S E E S + +++
Sbjct: 1515 ERSGSESSV--DQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP 1572
Query: 1475 RKDTFKKDSQQDIPS-SKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRK----- 1528
+ + S ++ S S+ +S + +P + S S++SP P+
Sbjct: 1573 LRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRAL 1632
Query: 1529 -RRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISS 1587
RR+ GSSS + S E S E R + S
Sbjct: 1633 PRRSRSGSSSKGRGPSPEGSSSTE------------------SSPEHPPKSRTARRGSRS 1674
Query: 1588 STESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRE 1647
S E + K T + + ++ LTRK+ S RR E +P ++R
Sbjct: 1675 SPEPKTKSRTPPRRR-SSRSSPELTRKARLS------RRSRSASSSPETRSRTPP-RHRR 1726
Query: 1648 TKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDS 1707
+ S S E RR + + S K L ++ T
Sbjct: 1727 SPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTR 1786
Query: 1708 PEDRSRGEGSSSLHASSFTPGTSPTS-----------VSSLDEDSDSSPSHKKGESKQQR 1756
DRS S+S + T + E S +S ++G S+
Sbjct: 1787 RRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPP 1846
Query: 1757 KARHRPHGPLLPTIEDSSEEE-------ELREEEELLKEQEKQREIEQQQRKSSSKKSKK 1809
+R R P S R L+ + + R+ S ++
Sbjct: 1847 TSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSV 1906
Query: 1810 DKDELRAQ-----RRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSI 1863
+ R++ RRR R +TPP +PT R + + R +P +
Sbjct: 1907 TRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPV 1965
Score = 90.5 bits (223), Expect = 4e-17
Identities = 318/1667 (19%), Positives = 568/1667 (34%), Gaps = 213/1667 (12%)
Query: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
P ++ TPG+ PA H+ ++ K + + G+ P + K PA
Sbjct: 105 PGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPA 164
Query: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK-TPAQQPGPAKPPTQQVGTPKPLA 422
P P E SS P PK + + ++ P + + K +
Sbjct: 165 ----PEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRS 220
Query: 423 QQPGLQSPAKAPGP-----------------TKTPVQQPGPGKIPAQQAGPGKTS----- 460
+ + ++P P T P + A A TS
Sbjct: 221 ESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSR 280
Query: 461 --AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG--SAKPPSQQPGSTKPPPQQPGP 516
A +T T + P PA + G P +PG S + PS +TK P P
Sbjct: 281 SAAAKTHTTALAGRSPSPASG---RRGEGDAPFSEPGTTSTQRPSSPETATKQP-SSPYE 336
Query: 517 AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ---STKPVSQTG-SGKPLQPPT- 571
K ++ S PS P + + P+P A++ S +P++ T S +P+ PP+
Sbjct: 337 DKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSE 396
Query: 572 VSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTE 631
SP+ + P PK+ PEK ++ +E P+P T+
Sbjct: 397 ASPTRDRSP----PKS--------------PEKLPQSSSSESSP---------PSPQPTK 429
Query: 632 VKEWLCLNCQMKRALG--GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAA 689
V + + + G + SSP K ++ +P + + A
Sbjct: 430 VSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPAT 489
Query: 690 PKQDLSKAPEP-KKPPPLVKQPTLHGSPSA----KAKQPPEADSLSKPAPPKEPSVPSEQ 744
K+ S++ P K+ + P S SA +++ P P P + Q
Sbjct: 490 AKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQ 549
Query: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQ 804
+ + + P T S S + S+ ++ ++ P + + S+
Sbjct: 550 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTR----RRSR 605
Query: 805 SFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSP 864
S P S + A R + S + S S+ + + P + S
Sbjct: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRR----SRSRSPARRSGRSRSRTPARRGRSRSR 661
Query: 865 KPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS-RRFSLNLGSITDAPKSQPTTP 923
P + + S TP R + TP + + + ++ RR S+ +S TP
Sbjct: 662 TPARRGRSR-SRTPA--RRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTP 718
Query: 924 QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKST 983
Q G S S S Q S S P MK++ S+ S P+S
Sbjct: 719 QRR--------GRSGSSSERKNKSRTSQRRSRSNSSP--EMKKSRISSRRSRSLSSPRSK 768
Query: 984 GQAPPAPAKSI------PVKKETKAPAAEKL---EPKAEQAPTVKRTETEKKPPPIKDSK 1034
++ + +S+ P +K P + +PKA+ +R+ + PPP + SK
Sbjct: 769 AKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSK 828
Query: 1035 SLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNP 1094
+ + + + P KS P + + N S P +C E +P
Sbjct: 829 TPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQR-RSCFES----------SP 877
Query: 1095 TPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQV 1154
P L ++ + SG S P+ P +S S+ ++ P+V
Sbjct: 878 DPELKS-------RTPSRHSCSGS-----------SPPRVKSSTPPRQSPSRSSSPQPKV 919
Query: 1155 KLVKKQEQEVKTEAEKVILEKVKETLSMEK--------------IPPMVTTDQKQEESKL 1200
K + Q + + +V + + +P + ++K+
Sbjct: 920 KAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKV 979
Query: 1201 EKD---KASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEK------KPTPEDKKLLPE 1251
+ + + S P P+ K P + S K P +EK + P L
Sbjct: 980 KPETPPRQSHSGSISPYPKVKAQTPPGPSL-SGSKSPCPQEKSKDSLVQSCPGSLSLCAG 1038
Query: 1252 AKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDD 1311
K+S P + + V + K + + +P + P+ + S + QS +
Sbjct: 1039 VKSSTPPGESY----FGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSP 1094
Query: 1312 KTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGIS 1371
K ++ P V ++ D+ + S+S KS + + SD S
Sbjct: 1095 KGGRSRSSSP----------VTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSS 1144
Query: 1372 SSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEK 1431
+ SL+ + + +K + + ++ K + + + + S+L K
Sbjct: 1145 YPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLV-FK 1203
Query: 1432 SEKKTQPHEVS--PEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPS 1489
+T P E S P+ +E+ +L + + E +++S+E S +
Sbjct: 1204 DTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEM 1263
Query: 1490 SKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ------ 1543
S + E S V++ D + + E VP G S E+K+
Sbjct: 1264 STSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWG-GPHFSPEHKELSNSPL 1322
Query: 1544 -EDSQGSGEEEDFIRKQIIEMS------ADEDASGS-----EDDEFIRNQLKEISSSTES 1591
E+S GS E EM+ ED +G E D + + + SS S
Sbjct: 1323 RENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHS 1382
Query: 1592 QKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQ 1651
+ K ++ ++ ++ R S E D P R ++S
Sbjct: 1383 SSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSG 1442
Query: 1652 ESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDR 1711
S L G G ++ +S S+ ++ EP ++L +P R
Sbjct: 1443 SSPGL--RDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEP----KALPQTPRPR 1496
Query: 1712 SRGEGSSSLHASSFTPGTSPT-SVSSLDEDSDS-SPSHKKGESKQQRKARHRPH-GPLLP 1768
SR S L+ TP + S SS+D+ + + +P ++ S ++ +P P
Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQER 1556
Query: 1769 TIEDSSEEEE------LREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELR-AQRRRE 1821
+ DSS + + LR+ E + R+S S S + KD+ R A R +
Sbjct: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS 1616
Query: 1822 RPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPE 1868
+ P +P A P R + R E S S ES PE
Sbjct: 1617 GSDSSPEPKAPAPRALPR---RSRSGSSSKGRGPSPEGSSSTESSPE 1660
Score = 88.2 bits (217), Expect = 2e-16
Identities = 186/915 (20%), Positives = 317/915 (34%), Gaps = 115/915 (12%)
Query: 48 LSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQ 107
+S R + +SR + + SV + S + + S P + R P
Sbjct: 1883 ISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTT 1942
Query: 108 PGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVS 167
S+SRT R + R+P ++ + S+SRT +S ++ + S S
Sbjct: 1943 RRRSRSRTPPVTRRRSR--SRTPP-VTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTS 1999
Query: 168 SVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGR 227
V + S+ T+ + ++ + + I+ + + P +P+++ R
Sbjct: 2000 PVTRR-----------RSRSRTSPVTR--RRSRSRTPPAIRRRSRSRTPL-LPRKRSRSR 2045
Query: 228 DPL-----QQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ 282
PL + TP++ ++ + PP + + + ++ A P R+ S +
Sbjct: 2046 SPLAIRRRSRSRTPRTARGKR--SLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSR 2103
Query: 283 TKQADIVRGESVKPSLPSPSKPPIQQ-------------PTPGKPPAQQPGHEKSQPGPA 329
T + S PS S P+ + TP Q G PGP
Sbjct: 2104 TPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPR 2163
Query: 330 KPPAQPSGLTKPLAQQP----------GTVKPP--VQPPGTTKPPAQPLGPAKPPAQQTG 377
P Q + + + AQ GT +PP + G +Q P + +T
Sbjct: 2164 IPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTA 2223
Query: 378 -SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGP 436
+ +S P A A +TPA P TP A L SP A P
Sbjct: 2224 PAANLASRIPAASAAAMNLASARTPAI---PTAVNLADSRTPAAAAAM-NLASPRTAVAP 2279
Query: 437 TKTPVQQPGPGKIPAQQAGPGKTSA-----QQTGPTKPPSQLPGPAKP-PPQQP------ 484
+ + P PA +T A TG PP+ P+ PQ P
Sbjct: 2280 SAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLV 2339
Query: 485 GP----AKPPPQQPGSAKPPSQQPGS---TKPPPQQPGPAKPSPQQP--------GSTKP 529
GP A P GS + P S + P G SP+ P G T P
Sbjct: 2340 GPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSP 2399
Query: 530 PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG--KPLQPPTVSPSAKQPPSQGLPKT 587
P ++ PS ++ +++++ P S+ G + L PP PS ++
Sbjct: 2400 PLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQS 2459
Query: 588 ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPN---------PHLTEVKEWLCL 638
C + TT P + + + T S G + PH +
Sbjct: 2460 RCLIAQTT------PVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAST 2513
Query: 639 NCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP 698
Q AL A P+ + ++ +++S+ S SS +S ++ + S
Sbjct: 2514 GAQQPSALA---ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570
Query: 699 EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPK 758
+P+ V PT + + +PPE P P K S + +
Sbjct: 2571 QPEVALKRVPSPTPAPKEAVREGRPPE------PTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 759 MVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDS 818
++ SSSS+++ SS S + K P A P + PP GE+ S
Sbjct: 2625 SSSSSS---SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK--PPPGERRSRSPR 2679
Query: 819 KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK-PMPKGSPT 877
K I DS+ +S+ P + Q P ++ + ++ + D++ P K
Sbjct: 2680 KPID-SLRDSRSLSY-SPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRE 2737
Query: 878 PPGPRPTAGQTVPTP 892
P PRP ++ +P
Sbjct: 2738 TPSPRPMRHRSSRSP 2752
Score = 87.4 bits (215), Expect = 3e-16
Identities = 298/1662 (17%), Positives = 520/1662 (31%), Gaps = 290/1662 (17%)
Query: 22 AGGGASGAGSPSHTAIP-AGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPS 80
+G G+S ++A+P + + +L ++ E+ ++S K SP
Sbjct: 1214 SGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPE 1273
Query: 81 MHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKS 140
+ + + + QS + P ++ S F E K SP L+E+
Sbjct: 1274 VEERPAVSLTLDQSQSQASLEAVEV--PSMASSWGGPHFSPEHKELSNSP----LRENSF 1327
Query: 141 RTDLKEEHK----SSMMPGFLSEVNALSAVSSVVNKFNPF--DLISDSEASQEETTKKQK 194
+ L+ + + M GF SEV + PF L +D +E + +
Sbjct: 1328 GSPLEFRNSGPLGTEMNTGFSSEVKE--------DLNGPFLNQLETDPSLDMKEQSTRSS 1379
Query: 195 VVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGT 254
+ P+ + K + P R P ++ +S S+ PE P
Sbjct: 1380 GHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRE----RSSSASSPEMKDGLPRTP 1435
Query: 255 GKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP 314
+ + + D + P + S DI R S S S P P +P
Sbjct: 1436 SRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRP 1495
Query: 315 PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ 374
++ P + P + SG + Q+ P Q + + P+ P +
Sbjct: 1496 RSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQE 1555
Query: 375 QTGSEK-PSSEQPGPKALAQPPGVGKTP-AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
++ S+ P S+ L Q G +P P + G+ + +P A+
Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ 1615
Query: 433 APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ 492
+ + + P P +P + + + P S P PP K
Sbjct: 1616 SGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP-------KSRTA 1668
Query: 493 QPGSAKPPSQQPGSTKPPPQQPGPAKP-----------------SPQQPGSTKPPSQQPG 535
+ GS P + S PP ++ + P SP+ T P ++
Sbjct: 1669 RRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRR-- 1726
Query: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595
PS P PA+ S + + + K SPS P +GL ++
Sbjct: 1727 --SPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPS---PKPRGLQRSRSRSRREK 1781
Query: 596 ELLLHVPEKANFNTCT-------ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGG 648
+++ + T ++ V H +R G
Sbjct: 1782 TRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGR 1841
Query: 649 DLAPVPSSPQPKLKTAPVTTTSAVSKSSP-----------------QPQQTSP------- 684
P S + + +T+P + S++SP +TSP
Sbjct: 1842 SRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSR 1901
Query: 685 -------KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS----AKAKQPPEADSLSKPA 733
++ + +S+ + PP+ ++ + +P+ ++++ PP S+
Sbjct: 1902 SRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSR 1961
Query: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
P S +P+ + + P T S S S + ++ +T+P
Sbjct: 1962 TPPVTRRRSRSRTSPIT--RRRSRSRTSPVTRRRSRSRT-------SPVTRRRSRSRTSP 2012
Query: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
+ S + PP + S + +PR S S+ S S+ + +
Sbjct: 2013 VTRRRSRSRT---PPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLT 2069
Query: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP-------------TPQQSPKPQE 900
A + S + + S TPP R +G P P SP P +
Sbjct: 2070 RSPPAIRRRSASGSSSDRSR-SATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLD 2128
Query: 901 QSR-----------RFSLNL-----GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASN 944
+ R R +++ GS+ D P + Q T + + +
Sbjct: 2129 RCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAI 2188
Query: 945 LISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP-AKSIPVKKETKAP 1003
+ TA P S +G A M Q PAP P S AP A A IP
Sbjct: 2189 SLGTARPPPSMSAAGLAARMSQVPAPV-------PLMSLRTAPAANLASRIPAASAAAMN 2241
Query: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK 1063
A P A + + T P + A P+ AV P+ + + T P
Sbjct: 2242 LASARTPAIPTAVNLADSRT-----PAAAAAMNLASPRTAVAPSAVNLADPRTPTAP--- 2293
Query: 1064 TELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIR 1123
NL G L L L +
Sbjct: 2294 ----------------------AVNLAGARTPAALAA----LSLTGSGTPPTAANYPSSS 2327
Query: 1124 KMPPAPS-----GPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVK- 1177
+ P AP+ GP+++ P + +TA + + +V
Sbjct: 2328 RTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPL 2387
Query: 1178 ---ETLSMEKIPPMV------TTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIR 1228
E +S PP++ T +S++ ++A + + + L+P +
Sbjct: 2388 SAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD-- 2445
Query: 1229 SEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIA--EEKLEGRVAPKTVQ 1286
+ + P P SA +Q L+ +A + G VA T
Sbjct: 2446 --------QPRSPVP-----------SAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSS 2486
Query: 1287 EGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKS 1346
G G+ S +P D QP A ++P KE+ S
Sbjct: 2487 AGDH-----NGMLSVPAPGVPHSDVGEPPASTGAQQPSALA---ALQPAKERRSSSSSSS 2538
Query: 1347 DTSSSQQPKSPQGLSDTGYSSDGISS----------SLGEIPSLIPTDEKDILKG----- 1391
+SSS S S + SS S +L +PS P ++ + +G
Sbjct: 2539 SSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEP 2598
Query: 1392 ----LKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPK 1447
K+ S S SS SS S + S+ S + +S+ + S + P SP +P
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP---SPAKPG 2655
Query: 1448 DQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRR 1507
Q K + P + + +S R
Sbjct: 2656 PQ----------------------------ALPKPASPKKPPPGERRSRSP--------R 2679
Query: 1508 EPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGS 1549
+P DS+ +S SPV +RR S S D+ +GS
Sbjct: 2680 KPIDSLRDSRSLSYSPV--ERRRPSPQPSPRDQQSSSSERGS 2719
Score = 82.4 bits (202), Expect = 1e-14
Identities = 216/1093 (19%), Positives = 366/1093 (33%), Gaps = 154/1093 (14%)
Query: 32 PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQ-----GLPKGSVPPAAAESPSMHRKQE 86
P H P+ + ++ S RR+ +A R + G P S S R+++
Sbjct: 1722 PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREK 1781
Query: 87 LDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSR----- 141
++ +SG R Q S+SR T R RSP+ + SR
Sbjct: 1782 TRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGR 1841
Query: 142 ------TDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKV 195
+ + ++S P S A A P S+ + +
Sbjct: 1842 SRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPL-------ISRRRSRSRTSP 1894
Query: 196 VQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQ-PPGT 254
V + + + + + P+ +++ R P +S + + +S+ PP T
Sbjct: 1895 VSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVT 1954
Query: 255 GKPIQG---PTQTPQTDHAKLPLQRDASRPQTKQADIVRGES-VKPSLPSPSKPPIQQPT 310
+ + P ++ P+ R SR +T R S P S+ T
Sbjct: 1955 RRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVT 2014
Query: 311 PGKPPAQQPGHEKSQPGPAKP--PAQPSGLTKPLA-QQPGTVKPPVQPPGTTKPPAQPLG 367
+ ++ P + + P P + S PLA ++ + P G P
Sbjct: 2015 RRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSP-- 2072
Query: 368 PAKPPAQQTGSEKPSSEQPGPKAL-----AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422
PA +GS S P A ++ P V ++ ++P TP
Sbjct: 2073 PAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSP--TPLDRC 2130
Query: 423 QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482
+ PG+ P + + +QQ G + GP Q+T + +Q
Sbjct: 2131 RSPGMLEPLGSSRTPMSVLQQAGGSMMDGP--GPRIPDHQRTSVPENHAQSRIALALTAI 2188
Query: 483 QPGPAKPPPQQP--GSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS 540
G A+PPP G A SQ P + PA S P + S
Sbjct: 2189 SLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAA----NLASRIPAASAAAMNLAS 2244
Query: 541 AQQPS-PAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLL 599
A+ P+ P + S P + V+PSA P P N
Sbjct: 2245 ARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTA--PAVNLA---- 2298
Query: 600 HVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQP 659
T SL G P R + P+
Sbjct: 2299 --------GARTPAALAALSLTGSGTPPTAANYPS-------SSRTPQAPASANLVGPRS 2343
Query: 660 KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS-- 717
TAPV + + ++ P + + AP + P+ P ++ + SP
Sbjct: 2344 AHATAPVNIAGSRTAAALAPASLTSAR-MAPALSGANLTSPRVPLSAYERVSGRTSPPLL 2402
Query: 718 --AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV------ADDKPKQPK----------M 759
A+++ PP A S S+ + PS S +AP A D+P+ P +
Sbjct: 2403 DRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCL 2462
Query: 760 VKPTTDLVSSSS------ATTK--------------PDIPSSKVQSQAEEKTTPPLKTDS 799
+ TT + S S ATT P +P S V PP T +
Sbjct: 2463 IAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGE-------PPASTGA 2515
Query: 800 AKPSQ--SFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857
+PS + P E+ S S + +S S S SS S G D +
Sbjct: 2516 QQPSALAALQPAKERRSSSSSSSSSSSSSSS---SSSSSSSSSSGSSSSDS-------EG 2565
Query: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK 917
+ + P+ K +P SPTP P+ + P P P ++ RR S + S + +
Sbjct: 2566 SSLPVQPEVALKRVP--SPTP-APKEAVREGRPP---EPTPAKRKRRSSSSSSSSSSSSS 2619
Query: 918 SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAP------APS 971
S ++ + + +S S +S+ + +PGP + P +P K P +P
Sbjct: 2620 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPR 2679
Query: 972 QPPTSQGPPKSTGQAP-----PAPAKSIPVKKETKAPAAEKLEPKAE----QAPTVKRTE 1022
+P S +S +P P+P P ++ ++ ++E+ + + ++P+ KR
Sbjct: 2680 KPIDSLRDSRSLSYSPVERRRPSPQ---PSPRDQQSSSSERGSRRGQRGDSRSPSHKRRR 2736
Query: 1023 TEKKPPPIKDSKS 1035
P P++ S
Sbjct: 2737 ETPSPRPMRHRSS 2749
Score = 80.9 bits (198), Expect = 3e-14
Identities = 233/1152 (20%), Positives = 390/1152 (33%), Gaps = 237/1152 (20%)
Query: 42 EADLSQLSEEERRQIAAVMSRAQGLPK------GSVPPAAAESPSMHRKQELDSSHPPKQ 95
E S++S R +++ S+A+ GS P +S + R+ SS P +
Sbjct: 748 EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAK 807
Query: 96 SGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPG 155
S P P S+S ++ + + K P R + S K ++ S
Sbjct: 808 SRTP--------PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS----- 854
Query: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQP 215
I+ +A+++ T +++ +
Sbjct: 855 -----------------------ITSPQANEQSVTPQRR---------------SCFESS 876
Query: 216 PKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ 275
P P K + P R S S P ++KS P P + + P+ P Q
Sbjct: 877 PDPELKSRTPSR---------HSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQ 927
Query: 276 RDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH--------EKSQPG 327
R S S PSPS+ + TP + + P S G
Sbjct: 928 RSHS---------------GSSSPSPSR-VTSRTTPRRSRSVSPCSNVESRLLPRYSHSG 971
Query: 328 PAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG 387
+ P + T P G++ P + T PP L +K P Q S K S Q
Sbjct: 972 SSSPDTKVKPETPPRQSHSGSISPYPKVKAQT-PPGPSLSGSKSPCPQEKS-KDSLVQSC 1029
Query: 388 PKAL--------AQPPGVG--------------KTPAQQPGPAKPPTQQVGTPKPLAQQP 425
P +L + PPG +P + + P +Q + P Q
Sbjct: 1030 PGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSK 1089
Query: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA----------------QQTGPTKP 469
SP + +PV + Q G S + PT
Sbjct: 1090 SQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVD 1149
Query: 470 PSQLPGPAK-PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP-----------A 517
+ L G ++ + PPQ+ +A PP +Q P P Q P
Sbjct: 1150 SNSLLGQSRLETAESKEKMALPPQEDATASPP-RQKDKFSPFPVQDRPESSLVFKDTLRT 1208
Query: 518 KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ----------------- 560
P + + P +++ SA P++ Q ++S +P Q
Sbjct: 1209 PPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNF 1268
Query: 561 TGSGKPLQPPTVSPSAKQPPSQ-GLPKTICPLCNTTELLLHV-PEKANFNTCTECQTTVC 618
S + + P VS + Q SQ L P ++ H PE + + +
Sbjct: 1269 ESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG 1328
Query: 619 SLCGF-NPNPHLTEVKEWLCLNCQMKRALGGD-LAPVPSSPQPKLK---------TAPVT 667
S F N P TE+ + ++K L G L + + P +K ++
Sbjct: 1329 SPLEFRNSGPLGTEMNTG--FSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSEL 1386
Query: 668 TTSAVSKSSPQPQQ--TSPKKDAAP----KQDLSKAPEPKKPPPLVKQPTLH----GSPS 717
+ AV K+ Q +SP DA P ++ S A P+ L + P+ SP
Sbjct: 1387 SPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPG 1446
Query: 718 AK-AKQPPEADSLSKPAP-----PKEPS-VPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770
+ P SLS +P P+ PS SE D +P P+ P+ + +
Sbjct: 1447 LRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELN 1506
Query: 771 SATTKPDIPSSKVQSQAEEKTT--PPLKTDS---------AKPSQSFPPTGEKVSPFDSK 819
+ P S +S ++KT PL S KPS S E S DSK
Sbjct: 1507 NKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSK 1566
Query: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSP----KPDAKPMPK-G 874
A R + S P +SK + P+++++ SP KP A P + G
Sbjct: 1567 AKTRTPLRQRSRSGSSPEVDSK---------SRLSPRRSRSGSSPEVKDKPRAAPRAQSG 1617
Query: 875 SPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGF 934
S + P P+ P P+ P+ + +S S G + S ++P+ +
Sbjct: 1618 SDSSPEPK------APAPRALPR-RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670
Query: 935 GASIFSQASNLISTAGQPGPHSQSGPGAP--MKQAPAPSQPPTSQGPPKSTGQAPP---- 988
G S++S T + P +S +P ++A + ++ P++ + PP
Sbjct: 1671 G----SRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRR 1726
Query: 989 APAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP--IKDSKSLTAEPQKAVLP 1046
+P+ S P E + + + + T R P P ++ S+S + +K
Sbjct: 1727 SPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRS-RSRREKTRTT 1785
Query: 1047 TKLEKSPKPEST 1058
+ ++S +ST
Sbjct: 1786 RRRDRSGSSQST 1797
Score = 72.0 bits (175), Expect = 1e-11
Identities = 93/447 (20%), Positives = 168/447 (37%), Gaps = 54/447 (12%)
Query: 122 EQKLPGRSPSTISLKESKSRTDLKEEH-------KSSMMPG--FLSEVNALSAVSSVVNK 172
+++ PG+ P+ + + K E S + G F + A A
Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEP 167
Query: 173 FNPFDLISDSEASQEETTK-KQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQ 231
P+ L+ +S +S+ T K K+K +K++G+ P +++ K + +
Sbjct: 168 PKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKR 227
Query: 232 QDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRG 291
+ +P S ++ + K + + P + ++ A D SR +++ A +
Sbjct: 228 KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSA-AAKT 286
Query: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351
+ + SPS P + G P +PG +Q
Sbjct: 287 HTTALAGRSPS-PASGRRGEGDAPFSEPGTTSTQR------------------------- 320
Query: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
P P TK P+ P ++ + +PS P P+ + P + PA P A+
Sbjct: 321 PSSPETATKQPSSPYEDKDKDKKEKSATRPS---PSPERSSTGP---EPPAPTPLLAE-- 372
Query: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
+ G+P+PLA P Q P P +P + P K P + P +S++ + P+ P+
Sbjct: 373 -RHGGSPQPLATTPLSQEPVNPPSEA-SPTRDRSPPKSPEKL--PQSSSSESSPPSPQPT 428
Query: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
++ A P+ P PA PGS + S P S + K P S
Sbjct: 429 KVSRHASSSPESPKPA----PAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRS 484
Query: 532 QQPGSAKPS-AQQPSPAKPSAQQSTKP 557
+ P +AK ++ +P K +S P
Sbjct: 485 RSPATAKRGRSRSRTPTKRGHSRSRSP 511
Score = 66.6 bits (161), Expect = 6e-10
Identities = 202/1110 (18%), Positives = 382/1110 (34%), Gaps = 138/1110 (12%)
Query: 27 SGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPK------GSVPPAAAESPS 80
S G S ++ P A S + ++ A+ M ++ P+ S +S S
Sbjct: 1093 SPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNS 1152
Query: 81 MHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTT---------------DTFRS---E 122
+ + L+++ ++ PP A P K + + DT R+ E
Sbjct: 1153 LLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRE 1212
Query: 123 QKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNA---LSAVSSVVNKFNPFDLI 179
+ G SP T KE S + + M SE A LS +SS + + + +
Sbjct: 1213 RSGAGSSPET---KEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFE 1269
Query: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQ--PPKPIPKQQGPGRDPLQQD--GT 235
S E + + Q E + P + P P+ + PL+++ G+
Sbjct: 1270 SSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGS 1329
Query: 236 PKSISSQQP---EKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGE 292
P + P E + + GP L ++ ++R + + +
Sbjct: 1330 PLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPD 1389
Query: 293 SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
+V+ + S S I P P + P E+S A P GL + +++ + P
Sbjct: 1390 AVEKAGMS-SNQSISSPVLDAVP-RTPSRERSSS--ASSPEMKDGLPRTPSRRSRSGSSP 1445
Query: 353 VQPPGTTKPPAQPLGPAKP-----PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGP 407
G+ P L + P P + P PKAL Q P +P
Sbjct: 1446 GLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTP--------RPRS 1497
Query: 408 AKPPTQQVGTP--KPLAQQPGLQSPAKAPGPTKTPVQQPG-----------PGKIPAQQA 454
P + ++ P ++ G +S +TP+ Q P P Q+
Sbjct: 1498 RSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP-QER 1556
Query: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514
+S T+ P + + P+ ++ P++ S P + P Q
Sbjct: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS 1616
Query: 515 GP-AKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
G + P P+ P P + + + PSP S+ +S+ P PP
Sbjct: 1617 GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESS----------PEHPPKSR 1666
Query: 574 PSAKQPPSQGLPKT---ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLT 630
+ + S PKT P ++ + KA + + ++ P H
Sbjct: 1667 TARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRR 1726
Query: 631 EVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPK-KDAA 689
+P SSP+P K+ ++ S SSP+ + TS + + +
Sbjct: 1727 --------------------SPSVSSPEPAEKSR--SSRRRRSASSPRTKTTSRRGRSPS 1764
Query: 690 PKQ---DLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK------EPSV 740
PK S++ ++ ++ GS + +++ + S S+ +
Sbjct: 1765 PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824
Query: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800
P+ Q+ + + + + PT+ S S + P S S A + ++ S
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHR-----RSRSR 1879
Query: 801 KPSQSFPPTGEKVSPFDSKAIPRPASDS--KIISHPGPSSESKGQKQVDPVQKKEE---- 854
P S + + SP + S + + S P S + + + PV ++
Sbjct: 1880 TPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRT 1939
Query: 855 PKKAQTKMSPKPDAKPMPKGSPTPP-GPRPTAGQTVPTPQQSPKPQEQ--SRRFSLNLGS 911
P + S P S TPP R + +T P ++ + + +RR S + S
Sbjct: 1940 PTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTS 1999
Query: 912 ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPS 971
+S+ T T +I ++ + T P S+S +++
Sbjct: 2000 PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRS--RTPLLPRKRSRSRSPLAIRRRSRSR 2057
Query: 972 QPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIK 1031
P T++G +S ++PPA + A + ++ P + + PP
Sbjct: 2058 TPRTARG-KRSLTRSPPA-------IRRRSASGSSSDRSRSATPPATRNHSGSRTPPVAL 2109
Query: 1032 DSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
+S ++ + ++ PT L++ P PL
Sbjct: 2110 NSSRMSCFSRPSMSPTPLDRCRSPGMLEPL 2139
Score = 45.1 bits (105), Expect = 0.002
Identities = 44/144 (30%), Positives = 63/144 (43%), Gaps = 14/144 (9%)
Query: 4833 DHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRS 4892
D G+ +S +QQ PS + + P+K+ + + S SS SS SSS S
Sbjct: 2505 DVGEPPASTGAQQ---PSALAALQ------PAKERRSSSSSSSSSSSSSSSSSSSSSSSS 2555
Query: 4893 HGPSRSQSKTSVTQTHLEDAGAAI-----AAAEAAVQQLRIQPTKPPNHRPAESSVSTGS 4947
G S S S+ S E A + A EA + +PT R + SS S+ S
Sbjct: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSS 2615
Query: 4948 SGSSFGSGYSVDSEGSSSTAGETN 4971
S SS S S S SSS++ ++
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSS 2639
Score = 44.7 bits (104), Expect = 0.002
Identities = 89/443 (20%), Positives = 163/443 (36%), Gaps = 59/443 (13%)
Query: 2161 SLILTYSEPSESATSVPPSD-TPSLTSSVSSVC--TTDSSSPITTLDSITTVYTEPVDMI 2217
+L LT S +A + P S TP +S + V + +++P+ S T P +
Sbjct: 2308 ALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLT 2367
Query: 2218 TKFE---------DSEEISSSTYFPGSIIDYPEEISVSLDRT---APPDGRASADHIVIS 2265
+ S + S Y S P + + RT AP R +++
Sbjct: 2368 SARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP 2427
Query: 2266 LSDMASSIIESVVP----KPEGPVADTVSTD--LLISEKDPVKKAKKETGNGIILEVLEA 2319
S M + +S++P +P PV S LI++ PV + +G + +
Sbjct: 2428 SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVA-GSQSLSSGAVATTTSS 2486
Query: 2320 YRDKKELEAERTKSSLSETVFDHP-------PSSVIAL-PMKEQLSTTYFTSGETFGQEK 2371
D + + V + P PS++ AL P KE+ S++ +S +
Sbjct: 2487 AGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSS 2546
Query: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
+S S S SS ++ + + P P P P PP P P
Sbjct: 2547 SSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTP------ 2600
Query: 2432 SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491
K++ + +S ++++ + ++ +++ S+ + +++ P P KP
Sbjct: 2601 -----AKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
Query: 2492 SIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSAD 2551
P PKP P+ P ++ + KP SL S +L+ + +
Sbjct: 2656 ----------------PQALPKPASPKKPPPGERRSRSPRKPID-SLRDSRSLS-YSPVE 2697
Query: 2552 YKLPSPTSPLSPHSNKSSPRFSK 2574
+ PSP + SS R S+
Sbjct: 2698 RRRPSPQPSPRDQQSSSSERGSR 2720
Score = 40.4 bits (93), Expect = 0.046
Identities = 87/454 (19%), Positives = 159/454 (35%), Gaps = 48/454 (10%)
Query: 3450 EDATDRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTK- 3508
E ++ RS ++++ KK D +++ P R R+K+ K S +E+ K K
Sbjct: 176 ESSSSRSPTPKQKKKKKKKDRGRRSESSS------PRRERKKSSKKKKHRSESESKKRKH 229
Query: 3509 ----PLSKVSSIAVQTVAEISVQTEPVG--TIRTPSIRARVDAKVEIIKHISAPEKTYKG 3562
P SK S + S P R+ S + + + SA KT+
Sbjct: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTT 289
Query: 3563 G--------SLGCQTEADSDTQSPQYLSA---TSPPKDKKRPTPLEIGYSSHLRADSTVQ 3611
+ G + E D+ P S +SP K+P+ + S +
Sbjct: 290 ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATR 349
Query: 3612 LAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLP------DDISPQKVLHPDMAKVP 3665
+PSP +S + P +P L +PL + ++P P + P
Sbjct: 350 PSPSPERSS----TGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405
Query: 3666 PASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLP 3725
P SP+ K+ Q S S+ P SP + SR + + ++ + A +
Sbjct: 406 PKSPE--KLPQSSSSESSPPSPQPTKVSR--------HASSSPESPKPAPAPGSHREISS 455
Query: 3726 NPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRKKQA 3785
+P + S G + RR+ R+ + A AK + R +R ++ R Q
Sbjct: 456 SPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAK--RGRSRSRTPTKRGHSRSRSPQW 513
Query: 3786 ELDEEEKEIDAKLRYLEMGINR--RKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTR 3843
+ G +R ++ + R + R + R +
Sbjct: 514 RRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS 573
Query: 3844 PTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQ 3877
+R ++ G R RT + P + ++ S+
Sbjct: 574 RSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSR 607
Score = 40.4 bits (93), Expect = 0.046
Identities = 50/231 (21%), Positives = 83/231 (35%), Gaps = 15/231 (6%)
Query: 3500 SMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKH---ISAP 3556
S+ + +P S V S + QT PV ++ S A H +S P
Sbjct: 2438 SLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP 2497
Query: 3557 EKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSP 3616
+G + A + Q P L+A P K+++ + SS + S+ + S
Sbjct: 2498 APGVPHSDVG-EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS 2556
Query: 3617 PKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQ 3676
S P+ P AL+ VP P P + + + P P AK +
Sbjct: 2557 GSSSSDSEGSSLPVQPEVALKR--VPSPTPAPKEA---------VREGRPPEPTPAKRKR 2605
Query: 3677 RSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNP 3727
RS S S ++ SS + + ++ S + +SS + P P
Sbjct: 2606 RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656
Score = 36.2 bits (82), Expect = 0.86
Identities = 66/314 (21%), Positives = 109/314 (34%), Gaps = 50/314 (15%)
Query: 3387 PPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVRGQYDDMGENMTDDPRSFKKIVDSGVQ 3446
PP S V E + ++K+ KK+ K RG+ + + +S KK +
Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKK----KDRGRRSESSSPRRERKKSSKKKKHRS-E 221
Query: 3447 TDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADK 3506
++ + RS + +R K + P R+A DS + +D
Sbjct: 222 SESKKRKHRSPTPKSKRKSKD-------KKRKRSRSTTPAPKSRRAHRSTSADSASSSDT 274
Query: 3507 TKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLG 3566
++ S+ ++ T A P R + + S+PE K S
Sbjct: 275 SRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP 334
Query: 3567 CQTEADSDTQSPQYLSATSPPKDKKR---------PTPLEIGYSSHLRADSTVQLAPSP- 3616
+ + D D + SAT P +R PTPL + S LA +P
Sbjct: 335 YE-DKDKDKKEK---SATRPSPSPERSSTGPEPPAPTPL----LAERHGGSPQPLATTPL 386
Query: 3617 ---PKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAK 3673
P +P SP SP K SP+K+ ++ P SP+ K
Sbjct: 387 SQEPVNPPSEASPTRDRSPPK-----------------SPEKLPQSSSSESSPPSPQPTK 429
Query: 3674 MMQRSMSDPKPLSP 3687
+ + + S P+ P
Sbjct: 430 VSRHASSSPESPKP 443
Score = 36.2 bits (82), Expect = 0.86
Identities = 51/211 (24%), Positives = 76/211 (36%), Gaps = 19/211 (9%)
Query: 2373 ASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP-PPT 2431
++Q PS + + P+ P + SA P P P P PP P P
Sbjct: 317 STQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGG 376
Query: 2432 SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPP-PVPPKP 2490
SP+P +P + A+P T + + LP + ++PP P P K
Sbjct: 377 SPQPLATTPLSQEPVNPPSEASP------TRDRSPPKSPEKLPQSSSSESSPPSPQPTKV 430
Query: 2491 SSIPSGLVFTHRPEPSKPPIAP--KPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTL---- 2544
S S PE KP AP I PT+ + + S T S +
Sbjct: 431 SRHASS-----SPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSR 485
Query: 2545 NLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
+ T+ + S T HS SP++ +S
Sbjct: 486 SPATAKRGRSRSRTPTKRGHSRSRSPQWRRS 516
Score = 36.2 bits (82), Expect = 0.86
Identities = 37/138 (26%), Positives = 50/138 (36%), Gaps = 14/138 (10%)
Query: 1703 SLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPS---------HKKGESK 1753
S + S S SSS +SS + +S +S SS S SSPS K K
Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666
Query: 1754 QQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKK---- 1809
+ R P P I+ + L + Q QQ SS + S++
Sbjct: 2667 KPPPGERRSRSPRKP-IDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRG 2725
Query: 1810 DKDELRAQRRRERPKTPP 1827
D +RRRE P P
Sbjct: 2726 DSRSPSHKRRRETPSPRP 2743
Score = 35.8 bits (81), Expect = 1.1
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 8/129 (6%)
Query: 4836 KSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGP 4895
+S SS+SS SP+P+ + SR P+ K P + SS +SK+ RSHG
Sbjct: 414 QSSSSESSPPSPQPTKV-SRHASSSPESPKPAPAPGSHREISSSPTSKN------RSHGR 466
Query: 4896 SRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRIQPTKPPNHRPAESSVSTGSSGSSFGSG 4955
++ S T + + A A+ + R PTK + R S +G
Sbjct: 467 AKRDKSHSHTPSRRMGRSRSPATAKRGRSRSR-TPTKRGHSRSRSPQWRRSRSAQRWGRS 525
Query: 4956 YSVDSEGSS 4964
S G S
Sbjct: 526 RSPQRRGRS 534
Score = 35.4 bits (80), Expect = 1.5
Identities = 41/134 (30%), Positives = 56/134 (41%), Gaps = 10/134 (7%)
Query: 4288 RSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSARTK---PTSLPI 4344
RSR S P LS +R S SS +K + A + S + SS K P +LP
Sbjct: 1576 RSRSGSSPEVDSKSRLSPRRSRSGSSPEVK-DKPRAAPRAQSGSDSSPEPKAPAPRALPR 1634
Query: 4345 -----SQSRGRIPIV-AQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSL 4398
S S+GR P +S E SP P + + P P + T + SS S
Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS 1694
Query: 4399 PEVQQHMREESRTR 4412
PE+ + R R+R
Sbjct: 1695 PELTRKARLSRRSR 1708
Score = 35.0 bits (79), Expect = 1.9
Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 8/136 (5%)
Query: 4840 SQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQ 4899
+Q +SP PS +S + Q + S S + +++ H S
Sbjct: 2443 AQDQPRSPVPSAFSDQSRCLIA------QTTPVAGSQSLSSGAVATTTSSAGDHNGMLSV 2496
Query: 4900 SKTSVTQTHLEDAGAAIAAAEAAVQQLRIQPTKPPNHRPAESSVSTGSSGSSFGSGYSVD 4959
V + + + A+ A + + +QP K + SS S+ SS SS S S
Sbjct: 2497 PAPGVPHSDVGEPPASTGAQQPSALAA-LQPAKERRSSSSSSSSSSSSSSSS-SSSSSSS 2554
Query: 4960 SEGSSSTAGETNLFPI 4975
S GSSS+ E + P+
Sbjct: 2555 SSGSSSSDSEGSSLPV 2570
Score = 33.1 bits (74), Expect = 7.3
Identities = 57/292 (19%), Positives = 115/292 (39%), Gaps = 45/292 (15%)
Query: 3486 TRSRRKARVGKYGDSMTEADKTKPLSKVS-SIAVQTVAEISVQTEPVGTIRTPSIRARVD 3544
+ SR R G+ G S +K++ + S S + + + + + ++ +P R++
Sbjct: 713 SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSP--RSKAK 770
Query: 3545 AKVEIIKHISA------------PEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKR 3592
+++ + + +S P ++ G S Q +A S T + S++SPP +K
Sbjct: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS---QPKAKSRTPPRRSRSSSSPPPKQKS 827
Query: 3593 PTPLEIGYSS---HLRADSTVQLAPSPPKSPKVLYSPISP-------LSPGKALESAFVP 3642
TP +SS H + S SP+ ++P SP L+S P
Sbjct: 828 KTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSR-TP 886
Query: 3643 YEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEG 3702
SP +V + P+ + + +++ P+ S + SS +P + T
Sbjct: 887 SRHSCSGS-SPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSG-SSSPSPSRVTSR 944
Query: 3703 YTTKGSQTM--------------TSSGAQKKVKRTLPNPPPEEISTGTQSTF 3740
T + S+++ + SG+ + P PP + +G+ S +
Sbjct: 945 TTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPY 996
Score = 32.7 bits (73), Expect = 9.6
Identities = 39/154 (25%), Positives = 58/154 (37%), Gaps = 14/154 (9%)
Query: 4836 KSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGP 4895
+S SSQ P S + PD + P ++S S S + S+ L P
Sbjct: 1538 RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSG-SSPEVDSKSRL---SP 1593
Query: 4896 SRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRIQPTKPPNHRPAESSVSTGSSGSSFGSG 4955
RS+S +S ++D A A++ + P PA ++ S S G
Sbjct: 1594 RRSRSGSS---PEVKDKPRAAPRAQSG------SDSSPEPKAPAPRALPRRSRSGSSSKG 1644
Query: 4956 YSVDSEGSSSTAGETNLFPIPRIGKMG-QNGQEP 4988
EGSSST P R + G ++ EP
Sbjct: 1645 RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEP 1678
Score = 32.7 bits (73), Expect = 9.6
Identities = 31/136 (22%), Positives = 50/136 (36%), Gaps = 4/136 (2%)
Query: 1437 QPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEK 1496
QP ++ QP + ++ S S + + S S + DS+ SS + +
Sbjct: 2517 QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG---SSLPVQPE 2573
Query: 1497 SEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFI 1556
+ P ++V E E +P +RKRR+S SSSS S S
Sbjct: 2574 VALKRVPSPTPAPKEAVREGRPPEPTPA-KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSS 2632
Query: 1557 RKQIIEMSADEDASGS 1572
S+ +S S
Sbjct: 2633 SSSSSSSSSSSSSSSS 2648
>gi|154354983 regulating synaptic membrane exocytosis 2 isoform a
[Homo sapiens]
Length = 1349
Score = 143 bits (361), Expect = 4e-33
Identities = 117/375 (31%), Positives = 185/375 (49%), Gaps = 69/375 (18%)
Query: 4496 RIKITRDSKDHTV---SGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEG 4552
RI + + KD +V SG LG+++VGGK SG + A+I K+ G A+ G L G
Sbjct: 581 RILLNKRLKDGSVPRDSGAMLGLKVVGGKMT--ESGRLCAFITKVKKGSLADTVGHLRPG 638
Query: 4553 MQVLEWNGIPLTSKTYEEVQSII--SQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKA 4610
+VLEWNG L T+EEV +II S+ + E+ V + + +S H +L +
Sbjct: 639 DEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESSSSS 698
Query: 4611 VDKAKSPGVDPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGS 4670
+ K +D ++ V+ SP +L V + S GQ S
Sbjct: 699 FESQK---MDRPSIS-----VTSPMSPGMLRDVPQFLS-----------------GQLSS 733
Query: 4671 PSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYD-LGN-LIIHILQARNLVPRDNNGYS 4728
S+S++ + P +Q+++ +D +G+ LI+ IL A++L R++
Sbjct: 734 QSLSRR--------------TTPFVPRVQIKLWFDKVGHQLIVTILGAKDLPSREDGRPR 779
Query: 4729 DPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLE 4788
+P+VK+Y LP R S + KRRTK V+K+L P+WNQT IY + + +++ LE
Sbjct: 780 NPYVKIYFLPDR---------SDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLE 830
Query: 4789 VTVWDYDRF--SSNDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQS 4846
+T+WD R ++FLGE+LI+L T+ LD+ P WY L QT + S
Sbjct: 831 ITLWDQARVREEESEFLGEILIEL-ETALLDDEPHWYKL--QTHDV-------SSLPLPH 880
Query: 4847 PKPSVIKSRSHGIFP 4861
P P + + + HG P
Sbjct: 881 PSPYMPRRQLHGESP 895
Score = 82.0 bits (201), Expect = 1e-14
Identities = 95/336 (28%), Positives = 146/336 (43%), Gaps = 54/336 (16%)
Query: 4830 ESIDHGKSHSSQSSQQSPKPSVIKSRSHGIF-PDPSKDMQVPTIEKSHSSPGSSKSSSEG 4888
E+ D H S+S++Q P +RS PD + +P++ S+P S + S
Sbjct: 1018 EAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAP-PSPALSRS 1076
Query: 4889 HLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRIQPTKPPNHRPAESSVSTGSS 4948
H R+ S S T V A +QL P K R A +
Sbjct: 1077 HPRTGSVQTSPSSTPV--------------AGRRGRQLPQLPPKGTLDRKAGGKKLRSTV 1122
Query: 4949 GSSFGSGYSVD-------------SEGS-SSTAGETNL-FPIPRIGKMGQ-----NGQEP 4988
S +G +V+ ++GS +S + E NL FP R+ Q +G P
Sbjct: 1123 QRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGP 1182
Query: 4989 VKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPD 5048
+ G T MG+I++ + M G QL VEI++ R + K S LP
Sbjct: 1183 AQLVG------RQTLATPAMGDIQVGM---MDKKG-QLEVEIIRARGLVVKPGSKT-LPA 1231
Query: 5049 LYVKIYVMNISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILLFSNGGKFMK 5108
YVK+Y+++ + KKKT+V R EP + + F SP G LQI+++ + G+
Sbjct: 1232 PYVKVYLLDNGVC--IAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDH 1289
Query: 5109 KTLIGEACIWLDKVDLRKRIVNWHKL-----LVSPT 5139
K+ +G A I LD+++L ++ W KL LV PT
Sbjct: 1290 KSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPT 1325
Score = 57.0 bits (136), Expect = 5e-07
Identities = 50/176 (28%), Positives = 82/176 (46%), Gaps = 20/176 (11%)
Query: 4686 GTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNG-YSDPFVKVYLLPGRGQVM 4744
G + ++ P G+IQ+ + G L + I++AR LV + + P+VKVYLL
Sbjct: 1187 GRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLL------- 1239
Query: 4745 VVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVW-DYDRFSSNDFL 4803
N K++TK +K+L P + Q + ++ E + K L++ VW DY R F+
Sbjct: 1240 --DNGVCIAKKKTKVARKTLEPLYQQLLSFE----ESPQGKVLQIIVWGDYGRMDHKSFM 1293
Query: 4804 GEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKS----HSSQSS-QQSPKPSVIKS 4854
G I L + W+ L + +D + +SQSS + S PS +S
Sbjct: 1294 GVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS 1349
Score = 35.8 bits (81), Expect = 1.1
Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 5012 KIALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPDLYVKIYVMNISTQKKVIKKKTRV 5071
++ +K G QLIV IL +++ + P YVKIY + + K K++T+
Sbjct: 746 RVQIKLWFDKVGHQLIVTILGAKDLPSREDGRPRNP--YVKIYFLPDRSDKN--KRRTKT 801
Query: 5072 CRHDREPSFNETFRFS 5087
+ EP +N+TF +S
Sbjct: 802 VKKTLEPKWNQTFIYS 817
Score = 34.3 bits (77), Expect = 3.3
Identities = 42/170 (24%), Positives = 65/170 (38%), Gaps = 35/170 (20%)
Query: 959 GPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA----EKLEPKAEQ 1014
GP + PA SQPP P P S ++E K A +K E + EQ
Sbjct: 6 GPRGRLAPIPAASQPPLQ----------PEMPDLSHLTEEERKIILAVMDRQKKEEEKEQ 55
Query: 1015 APTVK---RTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLC-KTELNIGS 1070
+ K + E K+ +S + QK P TC +C KT+ G
Sbjct: 56 SVLKKLHQQFEMYKEQVKKMGEESQQQQEQKGDAP-----------TCGICHKTKFADGC 104
Query: 1071 KDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLG 1120
+ C+ C+ + C CG + ++ W+C C+ Q+ I + G
Sbjct: 105 G-----HNCSYCQTKFCARCGGRVSLRSNKVM-WVCNLCRKQQEILTKSG 148
Score = 32.7 bits (73), Expect = 9.6
Identities = 41/204 (20%), Positives = 76/204 (37%), Gaps = 14/204 (6%)
Query: 3408 KQPKKRSSGAKVRGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKS 3467
+ +R + R +Y + T PRS D Q + + D ++S R ++S
Sbjct: 241 RDQNRRYDQREEREEYSQYATSDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRS 300
Query: 3468 VDTSVQ--TDDEDQDEWDMPTRSRRKARV-GKYGDSMTEAD---KTKPLSKVSSIAVQTV 3521
S + DDED + D R RR+ +Y A K +P + I +
Sbjct: 301 HRHSKEYIVDDEDVESRDEYERQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVS 360
Query: 3522 --------AEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADS 3573
+++S+ + R +R ++ I A + + S+ EA
Sbjct: 361 RARHERRHSDVSLANADLEDSRISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQG 420
Query: 3574 DTQSPQYLSATSPPKDKKRPTPLE 3597
+ Q + SPP ++ P P++
Sbjct: 421 PSSYAQRTTNHSPPTPRRSPLPID 444
>gi|41054864 regulating synaptic membrane exocytosis 1 [Homo sapiens]
Length = 1692
Score = 141 bits (355), Expect = 2e-32
Identities = 115/366 (31%), Positives = 166/366 (45%), Gaps = 84/366 (22%)
Query: 4509 SGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNGIPLTSKTY 4568
SG LG+++VGGK G +GA+I K+ G A+ G L G +VLEWNG PL T
Sbjct: 612 SGALLGLKVVGGKMTD--LGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATN 669
Query: 4569 EEVQSIISQQSGE--AEICVRLDLNMLSDSENSQHLELHEPPKAVDKAKSPGVDPKQLAA 4626
EEV +II + E EI V + + S H P ++ +
Sbjct: 670 EEVYNIILESKSEPQVEIIVSRPIGDIPRIPESSH---------------PPLESSSSSF 714
Query: 4627 ELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHGSSKPTDG 4686
E QK+ S SV SP PG+
Sbjct: 715 ESQKMERP------------------------SISVISPTSPGA---------------- 734
Query: 4687 TKVVSHPITGEIQLQINYD-LGN-LIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVM 4744
K + G++ +++ YD +G+ LI+++LQA +L R + +P+VK+Y LP R
Sbjct: 735 LKDAPQVLPGQLSVKLWYDKVGHQLIVNVLQATDLPARVDGRPRNPYVKMYFLPDR---- 790
Query: 4745 VVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRF--SSNDF 4802
S + KRRTK V+K L P+WNQT +Y + +++ LE+TVWD R ++F
Sbjct: 791 -----SDKSKRRTKTVKKILEPKWNQTFVYSHVHRRDFRERMLEITVWDQPRVQEEESEF 845
Query: 4803 LGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPD 4862
LGE+LI+L T+ LD+ P WY L+ E SS P+PS R H
Sbjct: 846 LGEILIEL-ETALLDDEPHWYKLQTHDE-----------SSLPLPQPSPFMPRRHIHGES 893
Query: 4863 PSKDMQ 4868
SK +Q
Sbjct: 894 SSKKLQ 899
Score = 77.4 bits (189), Expect = 3e-13
Identities = 99/416 (23%), Positives = 181/416 (43%), Gaps = 46/416 (11%)
Query: 4746 VQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGE 4805
++ AS + RT+ ++ ++ + QT S S ++L ++ D++ S D +
Sbjct: 1281 IEQASLVVEERTRQMKMKVH-RFKQTT--GSGSSQELDREQYSKYNIHKDQYRSCDNVSA 1337
Query: 4806 VLID--LSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHG--IFP 4861
D +S S + T L + + + + S +PK + + G I
Sbjct: 1338 KSSDSDVSDVSAISRTSSASRLSSTSFMSEQSERPRGRISSFTPKMQGRRMGTSGRSIMK 1397
Query: 4862 DPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQS---KTSVTQTHLEDAGAAIAA 4918
S ++ T+E + GS ++ G + + G R S K + + + ++
Sbjct: 1398 STSVSGEMYTLEHND---GSQSDTAVGTVGAGGKKRRSSLSAKVVAIVSRRSRSTSQLSQ 1454
Query: 4919 AEAAVQQLRI---QPTKPPNHRPAESSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPI 4975
E+ ++L+ + T+ V S S+ GS S SEG+ +FP
Sbjct: 1455 TESGHKKLKSTIQRSTETGMAAEMRKMVRQPSRESTDGSINSYSSEGNL-------IFPG 1507
Query: 4976 PRIGKMGQ-----NGQEPVKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEI 5030
R+G Q +G P + G T MG+I+I ++ + QL VE+
Sbjct: 1508 VRLGADSQFSDFLDGLGPAQLVG------RQTLATPAMGDIQIGMEDKKG----QLEVEV 1557
Query: 5031 LQCRNITYKFKSPDHLPDLYVKIYVMNISTQKKVIKKKTRVCRHDREPSFNETFRFSLSP 5090
++ R++T K S P YVK+Y++ + KKKTR+ R +P + ++ F SP
Sbjct: 1558 IRARSLTQKPGSKS-TPAPYVKVYLLENGAC--IAKKKTRIARKTLDPLYQQSLVFDESP 1614
Query: 5091 AGHSLQILLFSNGGKFMKKTLIGEACIWLDKVDLRKRIVNWHKL-----LVSPTQT 5141
G LQ++++ + G+ K +G A I L+++DL ++ W+KL LV PT T
Sbjct: 1615 QGKVLQVIVWGDYGRMDHKCFMGVAQILLEELDLSSMVIGWYKLFPPSSLVDPTLT 1670
Score = 49.3 bits (116), Expect = 1e-04
Identities = 117/567 (20%), Positives = 212/567 (37%), Gaps = 102/567 (17%)
Query: 537 AKPSA-QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595
AKP+A + P A+ Q + + Q Q + A++ QG K P C
Sbjct: 62 AKPAACKTPRNAENQPHQPSPRLHQQFESYKEQVRKIGEEARR--YQGEHKDDAPTCG-- 117
Query: 596 ELLLHVPEKANF--NTCTECQTTVCSLCGFN---PNPHLTEVKEWLCLNCQMKRALGGDL 650
+ H + A+ + C+ C+T C+ CG + + +V W+C C+ ++ +
Sbjct: 118 --ICHKTKFADGCGHLCSYCRTKFCARCGGRVSLRSNNEDKVVMWVCNLCRKQQEILTKS 175
Query: 651 AP--VPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVK 708
S PQ + ++ T+ + S P++ A Q+ S++ P
Sbjct: 176 GAWFFGSGPQQTSQDGTLSDTATGAGSE------VPREKKARLQERSRSQTPLSTAAASS 229
Query: 709 QPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVS 768
Q PSA PP+ SK A P + ++ EQ +A + + + P+ K T L
Sbjct: 230 QDA--APPSA----PPDR---SKGAEPSQQALGPEQKQAS-SRSRSEPPRERKKTPGLSE 279
Query: 769 SSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDS 828
+ K ++E K P KT SA+P + E+ +S+ + + S
Sbjct: 280 Q----------NGKGALKSERKRVP--KT-SAQPVEGAVEERERKERRESRRLEKGRSQ- 325
Query: 829 KIISHPG-PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
+P P +G+ + Q+KEE + + + P P+
Sbjct: 326 ---DYPDTPEKRDEGKAADEEKQRKEEDYQTRYRSDPNLARYPV---------------- 366
Query: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
P P+EQ R + + T G G +A
Sbjct: 367 -------KPPPEEQQMRMHARVSRARHERRHSDVALPRTEAGAALPEG-----KAGKRAP 414
Query: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
A + P P +P + + + G + T +PPAP PV E AP +
Sbjct: 415 AAARASP-----PDSPRAYSAERTAETRAPGAKQLTNHSPPAPRHG-PVPAE--APELKA 466
Query: 1008 LEPKAEQ-------APTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKP-ESTC 1059
EP +Q A +++ + EK +++ SL+++ ++V P+ PKP S
Sbjct: 467 QEPLRKQSRLDPSSAVLMRKAKREKVETMLRND-SLSSDQSESVRPS----PPKPHRSKR 521
Query: 1060 PLCKTELNIGSKD-----PPNFNTCTE 1081
K ++++ S + P + +C +
Sbjct: 522 GGKKRQMSVSSSEEEGVSTPEYTSCED 548
Score = 39.3 bits (90), Expect = 0.10
Identities = 116/634 (18%), Positives = 221/634 (34%), Gaps = 92/634 (14%)
Query: 996 VKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKP 1055
V ++ PAA K AE P ++ K+ E + + +P
Sbjct: 57 VVRDMAKPAACKTPRNAENQPHQPSPRLHQQFESYKEQVRKIGEEARRYQGEHKDDAP-- 114
Query: 1056 ESTCPLC-KTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLT---EIQEWLCLNCQT 1111
TC +C KT+ G + C+ C+ + C CG + ++ W+C C+
Sbjct: 115 --TCGICHKTKFADGCG-----HLCSYCRTKFCARCGGRVSLRSNNEDKVVMWVCNLCRK 167
Query: 1112 QRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKV 1171
Q+ I + G SGP+ + ++ T +V KK + ++ ++
Sbjct: 168 QQEILTKSGAWF----FGSGPQQTSQDGTLSDTA--TGAGSEVPREKKARLQERSRSQTP 221
Query: 1172 ILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEE 1231
+ S + PP D+ K P ++ L PE+++ S
Sbjct: 222 L--STAAASSQDAAPPSAPPDRS----------------KGAEPSQQALGPEQKQASSRS 263
Query: 1232 KKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQP 1291
+ E+K TP L + A + ++ + K+ Q +EG V + +E ++
Sbjct: 264 RSEPPRERKKTP---GLSEQNGKGALKSERKRVPKTSAQ----PVEGAVEERERKERRES 316
Query: 1292 QTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351
+ +G P + K D+ D+ + KE+ + +SD + +
Sbjct: 317 RRLEKGRSQDYPDTPEKRDEGKA--------------ADEEKQRKEEDYQTRYRSDPNLA 362
Query: 1352 QQPKSPQGLSDTGYSSDGISSSLGE----IPSLIPTDEKDILKGLKKDSFSQESSPSSPS 1407
+ P P +S + E +L T+ L K + ++ +SP
Sbjct: 363 RYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAGAALPEGKAGKRAPAAARASPP 422
Query: 1408 DLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEE 1467
D + S A A+ ++ Q SP P+ + E
Sbjct: 423 DSPRAYS---------AERTAETRAPGAKQLTNHSPPAPRHG----------PVPAEAPE 463
Query: 1468 IKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQR 1527
+K + RK + + D + K +EK E + R + S + S + P P R
Sbjct: 464 LKAQEPLRKQS-RLDPSSAVLMRKAKREKVETM----LRNDSLSSDQSESVRPSPPKPHR 518
Query: 1528 KRR----TSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLK 1583
+R + SSS+E + + E+ + + + D D + + +
Sbjct: 519 SKRGGKKRQMSVSSSEEEGVSTPEYTSCEDVELESESVSEKGDLDYYWLDPATWHSRETS 578
Query: 1584 EISSS--TESQKKEETKGKGKITAGKHRRLTRKS 1615
ISS T KE + G++ K + + S
Sbjct: 579 PISSHPVTWQPSKEGDRLIGRVILNKRTTMPKDS 612
Score = 36.6 bits (83), Expect = 0.66
Identities = 63/285 (22%), Positives = 104/285 (36%), Gaps = 41/285 (14%)
Query: 322 EKSQPGPAKPPAQPSGLTKPLA-----QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQT 376
+ SQ G A +G P Q+ + P+ + A P P+ PP +
Sbjct: 186 QTSQDGTLSDTATGAGSEVPREKKARLQERSRSQTPLSTAAASSQDAAP--PSAPPDRSK 243
Query: 377 GSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG---LQSPAKA 433
G+E PS + GP+ + A ++PP ++ TP L++Q G L+S K
Sbjct: 244 GAE-PSQQALGPE---------QKQASSRSRSEPPRERKKTP-GLSEQNGKGALKSERKR 292
Query: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQ------QTGPTKPPSQLPGPAKPPPQQPGPA 487
T QP G + ++ + S + Q P P + G A +Q
Sbjct: 293 VPKTSA---QPVEGAVEERERKERRESRRLEKGRSQDYPDTPEKRDEGKAADEEKQ---R 346
Query: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS-------PQQPGSTKPPSQQPGSAKPS 540
K Q P+ KPPP++ + ++ P + G+A P
Sbjct: 347 KEEDYQTRYRSDPNLARYPVKPPPEEQQMRMHARVSRARHERRHSDVALPRTEAGAALPE 406
Query: 541 AQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585
+ A P+A +++ P S T +P AKQ + P
Sbjct: 407 GKAGKRA-PAAARASPPDSPRAYSAERTAETRAPGAKQLTNHSPP 450
Score = 35.8 bits (81), Expect = 1.1
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 5023 GEQLIVEILQCRNITYKFKSPDHLPDLYVKIYVMNISTQKKVIKKKTRVCRHDREPSFNE 5082
G QLIV +LQ ++ + P YVK+Y + + K K++T+ + EP +N+
Sbjct: 756 GHQLIVNVLQATDLPARVDGRPRNP--YVKMYFLPDRSDKS--KRRTKTVKKILEPKWNQ 811
Query: 5083 TFRFS 5087
TF +S
Sbjct: 812 TFVYS 816
Score = 34.7 bits (78), Expect = 2.5
Identities = 47/208 (22%), Positives = 79/208 (37%), Gaps = 41/208 (19%)
Query: 26 ASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLP--------KGSVPPAAAE 77
A+GAGS +P +A L + S + A S P KG+ P A
Sbjct: 197 ATGAGSE----VPREKKARLQERSRSQTPLSTAAASSQDAAPPSAPPDRSKGAEPSQQAL 252
Query: 78 SPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTIS--L 135
P + S PP++ R PGLS+ +SE+K R P T + +
Sbjct: 253 GPEQKQASSRSRSEPPRE--------RKKTPGLSEQNGKGALKSERK---RVPKTSAQPV 301
Query: 136 KESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKV 195
+ + + KE +S + S+ + + + + +A+ EE +K++
Sbjct: 302 EGAVEERERKERRESRRLEKGRSQ-----------DYPDTPEKRDEGKAADEEKQRKEED 350
Query: 196 VQKEQGKPEGIIKPPLQQQPPKPIPKQQ 223
Q P L + P KP P++Q
Sbjct: 351 YQTRYRS-----DPNLARYPVKPPPEEQ 373
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 139 bits (349), Expect = 9e-32
Identities = 224/1046 (21%), Positives = 319/1046 (30%), Gaps = 156/1046 (14%)
Query: 210 PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGT---GKPIQGPTQTPQ 266
P+ + P P P P P + + P + PP T PI T P
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450
Query: 267 TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
T P+ + P T + PS P+ + P T PP P + P
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPS---PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507
Query: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386
PPA + L P T PP TT P P PP T ++ P
Sbjct: 1508 --ITPPASTTTLPPTTTPSPPTTTTTTPPP-TTTPSPPTTTPITPPTSTTTLPPTTTPSP 1564
Query: 387 GPKALAQPPGVGKTPAQQPGP-----AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
P PP P P P PPT TP P + P PT TP
Sbjct: 1565 PPTTTTTPP-----PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTP- 1618
Query: 442 QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP----AKPPPQQPGSA 497
P P T T P+ PP+ P PP P P PP +
Sbjct: 1619 --SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP--PPTTTPSPPTTTTPSPPITTTTT 1674
Query: 498 KPPSQQPGS---TKPPPQQPGPAKPSP-----------QQPGSTKPPSQQPGSAKPSAQQ 543
PP+ P S T P P PSP P ST PS P + +
Sbjct: 1675 PPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734
Query: 544 PSPAKPSAQQSTKPVSQTGS---GKPLQPPTVSPSAKQPPSQGLPKTIC-PLCN------ 593
+P+ P+ +T P + T S PL PP+++P P S P T C PLCN
Sbjct: 1735 TTPSPPTTTMTTLPPTTTSSPLTTTPL-PPSITPPTFSPFSTTTPTTPCVPLCNWTGWLD 1793
Query: 594 -----------TTELLLHV--PEKANFNTCTEC-----------QTTVCS-----LCGFN 624
TEL+ V P A +C QT VC +C
Sbjct: 1794 SGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNE 1853
Query: 625 PNPHLTEVKEWLCLN-------CQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSP 677
+ CLN C+ +P P T TTT+ +P
Sbjct: 1854 DQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTP 1913
Query: 678 QPQQTSPKKDAAPKQDLSKAPEP-----KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732
QT ++ P P P+ T+ +P+ Q P ++
Sbjct: 1914 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1973
Query: 733 ---APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789
P P+ P+ P T +++ TT + + + +
Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2033
Query: 790 KTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV 849
TT P+ T + + + PTG + P + + ++ P P+ P+
Sbjct: 2034 PTTTPI-TTTTTVTPTPTPTGTQT------PTTTPITTTTTVT-PTPTPTGTQTPTTTPI 2085
Query: 850 QKKEEPKKAQTKMSPK-PDAKPMPKGSPTPPGPRPTAGQT------VPTPQQSPKPQEQS 902
T + P P+ + P P PT QT T +P P
Sbjct: 2086 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2145
Query: 903 RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP---HSQSG 959
T P + P T TVT G + +T P P +Q+
Sbjct: 2146 ----------TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2195
Query: 960 PGAPMKQAP--APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPT 1017
P+ P+ PT P +T P T+ P + PT
Sbjct: 2196 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2255
Query: 1018 VKRTETE-KKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNF 1076
T T+ PI + ++T PT + +T P+ T + P
Sbjct: 2256 PTPTGTQTPTTTPITTTTTVT--------PTPTPTGTQTPTTTPI--TTTTTVTPTPTPT 2305
Query: 1077 NTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSG---PK 1133
T T + PTP T Q T ++ P P+G P
Sbjct: 2306 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT--------PTPTPTGTQTPT 2357
Query: 1134 ASPM-------PVPTESSSQKTAVPP 1152
+P+ P PT + +Q P
Sbjct: 2358 TTPITTTTTVTPTPTPTGTQTPTTTP 2383
Score = 108 bits (270), Expect = 1e-22
Identities = 174/849 (20%), Positives = 264/849 (31%), Gaps = 83/849 (9%)
Query: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPT--QTPQTDHAKLPLQRDASRPQTKQADIVRGE 292
TP +Q P T P PT QTP T P+ + T +
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVTPTPTPTGTQTP 3690
Query: 293 SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
+ P + + P PT + P P + P P T TV P
Sbjct: 3691 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3750
Query: 353 VQPPGTTKPPAQPLGPAK---PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK 409
P GT P P+ P TG++ P++ P TP P
Sbjct: 3751 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTT 3807
Query: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ-PGPGKIPAQQAGPGKTSAQQTGPTK 468
P T P G Q+P P T T V P P P T+ T PT
Sbjct: 3808 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTP 3866
Query: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP------------PSQQPGSTKPPPQQP-- 514
P+ P P P P G+ P P+ P T+ P P
Sbjct: 3867 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3926
Query: 515 --GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQ-STKPVSQTGSGKPLQPPT 571
P+P P T+ P+ P + + P+P Q +T P++ T + PT
Sbjct: 3927 TTTTVTPTPT-PTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTT----VTPT 3980
Query: 572 VSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTE 631
+P+ Q P T P+ TT + P T T T + + P P T
Sbjct: 3981 PTPTGTQTP------TTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4031
Query: 632 VKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPK 691
+ + P P+ Q T TTT+ +P QT
Sbjct: 4032 TQTPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4089
Query: 692 QDLSKAPEPK-----KPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA---PPKEPSVPSE 743
++ P P P+ T+ +P+ Q P ++ P P+
Sbjct: 4090 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4149
Query: 744 QDKAPVADDKPKQPKMVK-----PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD 798
P+ P PTT +++++ T P+ +T P+
Sbjct: 4150 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPI--- 4206
Query: 799 SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKA 858
A+ + S PP E +P S++ P ++S + P +
Sbjct: 4207 -AELTTSNPPP-ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG 4264
Query: 859 QTKMSPKPDAKPMPKGSPT-------PPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGS 911
+SP P P G+PT P P+ QT T +P P S +
Sbjct: 4265 GHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTG 4324
Query: 912 ITDAPKSQPT---------TPQETVTGKLFGFGASIFS-QASNLISTAGQPGPHSQSGPG 961
+ P S P E V +G + S + P + S
Sbjct: 4325 LRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTP 4384
Query: 962 APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT 1021
P K P PS+P ++ P + P P P ++ + + TV+
Sbjct: 4385 TPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIV 4444
Query: 1022 ETEKKPPPI 1030
+ E +PPP+
Sbjct: 4445 KVECEPPPM 4453
Score = 107 bits (267), Expect = 3e-22
Identities = 192/933 (20%), Positives = 278/933 (29%), Gaps = 120/933 (12%)
Query: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPT--QTPQTDHAKLPLQRDASRPQTKQADIVRGE 292
TP +Q P T P PT QTP T P+ + T +
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVTPTPTPTGTQTP 3483
Query: 293 SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
+ P + + P PT + P P + P P T TV P
Sbjct: 3484 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3543
Query: 353 VQPPGTTKPPAQPLGPAK---PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK 409
P GT P P+ P TG++ P++ P TP P
Sbjct: 3544 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTT 3600
Query: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV-QQPGPGKIPAQQAGPGKTSAQQTGPTK 468
P T P G Q+P P T T V P P P T+ T PT
Sbjct: 3601 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTP 3659
Query: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP------------PSQQPGSTKPPPQQP-- 514
P+ P P P P G+ P P+ P T+ P P
Sbjct: 3660 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3719
Query: 515 --GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ-QSTKPVSQTGSGKPLQPPT 571
P+P P T+ P+ P + + P+P Q +T P++ T + PT
Sbjct: 3720 TTTTVTPTP-TPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTT----VTPT 3773
Query: 572 VSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTE 631
+P+ Q P T P+ TT + P T T T + + P P T
Sbjct: 3774 PTPTGTQTP------TTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTP--TP 3822
Query: 632 VKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPK 691
+ P P+ Q T TTT+ +P QT
Sbjct: 3823 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3882
Query: 692 QDLSKAPEP-----KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP---APPKEPSVPSE 743
++ P P P+ T+ +P+ Q P ++ P P+
Sbjct: 3883 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3942
Query: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA--- 800
P+ P T +++ TT + + + + TT P+ T +
Sbjct: 3943 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4002
Query: 801 --KPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKA 858
P+ + PT ++ + P P P + + + P
Sbjct: 4003 TPTPTGTQTPTTTPITT-TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4061
Query: 859 QTKMSPKPDAKPMPKGSPTP------------PGPRPTAGQT------VPTPQQSPKPQE 900
+ P P G+ TP P P PT QT T +P P
Sbjct: 4062 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4121
Query: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960
T P + P T TVT G + +T P P + +G
Sbjct: 4122 TG----------TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGT 4170
Query: 961 GAPMKQ--------APAPSQPPTSQGPPKSTGQAP--------PAPAKSIP-VKKETKAP 1003
P P P+ T GPP T AP P P S P + T +P
Sbjct: 4171 QTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSP 4230
Query: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK 1063
E + P ++ T T PP + + T+ P SP T
Sbjct: 4231 LTESTTLLSTLPPAIEMTST--APPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPT----- 4283
Query: 1064 TELNIGSKDPPNFNTCTECKNQVCNLCGFNPTP 1096
GS P +T Q + PTP
Sbjct: 4284 RGTTTGSSSAPTPSTV-----QTTTTSAWTPTP 4311
Score = 105 bits (262), Expect = 1e-21
Identities = 178/797 (22%), Positives = 261/797 (32%), Gaps = 103/797 (12%)
Query: 2165 TYSEPSESATSVPPSDTPS--LTSSVSSVCTTDSSSPITTLDS--ITTVYTEPVDMITKF 2220
T S P S T++PP+ TPS T++ + TT S PITT + TT + P+ T
Sbjct: 1405 TPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTP 1464
Query: 2221 EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPK 2280
+ S T P P + + T PP + ++ AS+
Sbjct: 1465 PPTTTPSPPTTTPSPPTTTPSPPTTT--TTTPPPTTTPSPPTTTPITPPASTTTLPPTTT 1522
Query: 2281 PEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVF 2340
P P T + + P T
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPT------------------------------------TTP 1546
Query: 2341 DHPPSSVIALPMKEQLS---TTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSS 2397
PP+S LP S TT T T P + PS P++++ P
Sbjct: 1547 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS-PPTITTTTPPPTTTPSPP 1605
Query: 2398 SLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP---TILPKKKLTVASPVTTATP 2454
+ + PP P PP P PP LPP T+P P T T SP TT TP
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1665
Query: 2455 LFDAVTTLETTAVLRSNGLPVTRICTTAPPP----VPPKPSSIPSGLVFT-----HRPEP 2505
+TT T + P+T TT PP P P++ PS + T P
Sbjct: 1666 -SPPITTTTTPPPTTTPSSPIT---TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTP 1721
Query: 2506 SKPP---IAPKP-VIPQLPTTTQKPTDIHPKPTGLSLTSS---MTLNLVTSADYKLPSPT 2558
S PP P P P PTTT T + P T LT++ ++ T + + +PT
Sbjct: 1722 SPPPTTMTTPSPTTTPSPPTTTM--TTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPT 1779
Query: 2559 SPLSPHSN------KSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKD 2612
+P P N P F K +T ++ + S + P+G +
Sbjct: 1780 TPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQT 1839
Query: 2613 LVSVEPVFSVV-----PPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVT 2667
+V V + P + + + T +T ++ P + T
Sbjct: 1840 VVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTT 1899
Query: 2668 QFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDV 2727
TT + T + P+ + + T+ P P Q + V
Sbjct: 1900 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTTTV 1953
Query: 2728 IDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTP 2787
T + TT +T V T G Q P +VT + TP
Sbjct: 1954 TPTPTPTGTQTPTTTPI----TTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPT-PTP 2005
Query: 2788 VSLATETVTFVTCTASASYTTGTESLVGAEHAMTTPLQLTTSKHAEPP---YRIPSDQVF 2844
T T T +T T + T T + G + TTP+ TT+ P + P+
Sbjct: 2006 TGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2062
Query: 2845 PIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTK 2904
P GT T IT TV P G T + T V T
Sbjct: 2063 TTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2121
Query: 2905 SHRTVVTMDESTSSVMT 2921
+T T +T++ +T
Sbjct: 2122 GTQTPTTTPITTTTTVT 2138
Score = 104 bits (259), Expect = 3e-21
Identities = 159/648 (24%), Positives = 224/648 (34%), Gaps = 78/648 (12%)
Query: 2331 TKSSLSETVFDHPPSSVIALPMKEQLS---TTYFTSGETFGQEKPASQLPSGSPSVSSLP 2387
T S T PP+S LP S TT T T P + + P+ + P
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456
Query: 2388 -----AKPRPFFRSSSLDISAQPPPPPPPPPPP------PPPPPPPPPP----------- 2425
P P S + P PP P PP PPP P PP
Sbjct: 1457 PISTTTTPPPTTTPSPP--TTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514
Query: 2426 -PLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPP 2484
LPP T+P P P T P TT +P TT T + LP T T +PP
Sbjct: 1515 TTLPPTTTPSP---PTTTTTTPPPTTTPSP----PTTTPITPPTSTTTLPPT--TTPSPP 1565
Query: 2485 P---VPPKPSSIPSGLVFTHRPEP----SKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLS 2537
P P P++ PS T P + PP P P TTT PT PT
Sbjct: 1566 PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1625
Query: 2538 LTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSA 2597
+T + + P PT+ +P ++P + T + + T + P T T SS
Sbjct: 1626 ITPPTSTTTLPPTTTPSPPPTTTTTPPPT-TTPSPPTTTTPSPPITTTTTPPPTTTPSS- 1683
Query: 2598 SQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPS 2657
IT+ P P+ + + P + P+T P S+ + T +P T PS
Sbjct: 1684 --PITTTP-SPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTT--PSPTTTPS 1738
Query: 2658 SFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP-LALDN----IHLEK 2712
T++ T+ T T P+ S S T P P + L N + K
Sbjct: 1739 PPTTTMTTLPPTTTSSPLTTTPLPPSITPPT--FSPFSTTTPTTPCVPLCNWTGWLDSGK 1796
Query: 2713 PQY-KEDGKLQLVGDVIDLRTVPKVEVKTT---DKCIDLSASTM--DVKRQITANEVYGK 2766
P + K G +L+GDV + + T D I T+ DV + K
Sbjct: 1797 PNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQK 1856
Query: 2767 QISAVQPSI-----INLSVTSSIVTPVSLATETVTFVTCTASASYT-----TGTESLVGA 2816
+ + IN+ + P ++ T T T + T T T + G
Sbjct: 1857 PGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGT 1916
Query: 2817 EHAMTTPLQLTTSKHAEPP---YRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVT 2873
+ TTP+ TT+ P + P+ P GT T IT T
Sbjct: 1917 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTT 1975
Query: 2874 VPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMT 2921
V P G T + T V T +T T +T++ +T
Sbjct: 1976 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2023
Score = 101 bits (252), Expect = 2e-20
Identities = 195/972 (20%), Positives = 293/972 (30%), Gaps = 115/972 (11%)
Query: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPT--QTPQTDHAKLPLQRDASRPQTKQADIVRGE 292
TP +Q P T P PT QTP T P+ + T +
Sbjct: 2002 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVTPTPTPTGTQTP 2057
Query: 293 SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
+ P + + P PT + P P + P P T TV P
Sbjct: 2058 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2117
Query: 353 VQPPGTTKPPAQPLGPAK---PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK 409
P GT P P+ P TG++ P++ P TP P
Sbjct: 2118 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTT 2174
Query: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV-QQPGPGKIPAQQAGPGKTSAQQTGPTK 468
P T P G Q+P P T T V P P P T+ T PT
Sbjct: 2175 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTP 2233
Query: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP------------PSQQPGSTKPPPQQP-- 514
P+ P P P P G+ P P+ P T+ P P
Sbjct: 2234 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2293
Query: 515 --GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ-QSTKPVSQTGSGKPLQPPT 571
P+P P T+ P+ P + + P+P Q +T P++ T + PT
Sbjct: 2294 TTTTVTPTP-TPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTT----VTPT 2347
Query: 572 VSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTE 631
+P+ Q P T P+ TT + P T T T + + P P T
Sbjct: 2348 PTPTGTQTP------TTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTP--TP 2396
Query: 632 VKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPK 691
+ P P+ Q T TTT+ +P QT
Sbjct: 2397 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2456
Query: 692 QDLSKAPEP-----KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP---APPKEPSVPSE 743
++ P P P+ T+ +P+ Q P ++ P P+
Sbjct: 2457 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2516
Query: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS 803
P+ P T +++ TT + + + + TT P+ T + +
Sbjct: 2517 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVT 2575
Query: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS 863
+ PTG + P + + ++ P P+ P+ T
Sbjct: 2576 PTPTPTGTQT------PTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2628
Query: 864 PK-PDAKPMPKGSPTPPGPRPTAGQT------VPTPQQSPKPQEQSRRFSLNLGSITDAP 916
+ P P+ + P P PT QT T +P P T P
Sbjct: 2629 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG----------TQTP 2678
Query: 917 KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP---HSQSGPGAPMKQAP--APS 971
+ P T TVT G + +T P P +Q+ P+ P+
Sbjct: 2679 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2738
Query: 972 QPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE-KKPPPI 1030
PT P +T P T+ P + PT T T+ PI
Sbjct: 2739 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2798
Query: 1031 KDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLC 1090
+ ++T PT + +T P+ T + P T T +
Sbjct: 2799 TTTTTVT--------PTPTPTGTQTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTT 2848
Query: 1091 GFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSG---PKASPM-------PVP 1140
PTP T Q T ++ P P+G P +P+ P P
Sbjct: 2849 TVTPTPTPTGTQTPTTTPITTTTTVT--------PTPTPTGTQTPTTTPITTTTTVTPTP 2900
Query: 1141 TESSSQKTAVPP 1152
T + +Q P
Sbjct: 2901 TPTGTQTPTTTP 2912
Score = 101 bits (252), Expect = 2e-20
Identities = 195/972 (20%), Positives = 293/972 (30%), Gaps = 115/972 (11%)
Query: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPT--QTPQTDHAKLPLQRDASRPQTKQADIVRGE 292
TP +Q P T P PT QTP T P+ + T +
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVTPTPTPTGTQTP 2770
Query: 293 SVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
+ P + + P PT + P P + P P T TV P
Sbjct: 2771 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2830
Query: 353 VQPPGTTKPPAQPLGPAK---PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK 409
P GT P P+ P TG++ P++ P TP P
Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTT 2887
Query: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV-QQPGPGKIPAQQAGPGKTSAQQTGPTK 468
P T P G Q+P P T T V P P P T+ T PT
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTP 2946
Query: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP------------PSQQPGSTKPPPQQP-- 514
P+ P P P P G+ P P+ P T+ P P
Sbjct: 2947 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006
Query: 515 --GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ-QSTKPVSQTGSGKPLQPPT 571
P+P P T+ P+ P + + P+P Q +T P++ T + PT
Sbjct: 3007 TTTTVTPTP-TPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTT----VTPT 3060
Query: 572 VSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTE 631
+P+ Q P T P+ TT + P T T T + + P P T
Sbjct: 3061 PTPTGTQTP------TTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTP--TP 3109
Query: 632 VKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPK 691
+ P P+ Q T TTT+ +P QT
Sbjct: 3110 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3169
Query: 692 QDLSKAPEP-----KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP---APPKEPSVPSE 743
++ P P P+ T+ +P+ Q P ++ P P+
Sbjct: 3170 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3229
Query: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS 803
P+ P T +++ TT + + + + TT P+ T + +
Sbjct: 3230 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVT 3288
Query: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS 863
+ PTG + P + + ++ P P+ P+ T
Sbjct: 3289 PTPTPTGTQT------PTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3341
Query: 864 PK-PDAKPMPKGSPTPPGPRPTAGQT------VPTPQQSPKPQEQSRRFSLNLGSITDAP 916
+ P P+ + P P PT QT T +P P T P
Sbjct: 3342 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG----------TQTP 3391
Query: 917 KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP---HSQSGPGAPMKQAP--APS 971
+ P T TVT G + +T P P +Q+ P+ P+
Sbjct: 3392 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3451
Query: 972 QPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE-KKPPPI 1030
PT P +T P T+ P + PT T T+ PI
Sbjct: 3452 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3511
Query: 1031 KDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLC 1090
+ ++T PT + +T P+ T + P T T +
Sbjct: 3512 TTTTTVT--------PTPTPTGTQTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTT 3561
Query: 1091 GFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSG---PKASPM-------PVP 1140
PTP T Q T ++ P P+G P +P+ P P
Sbjct: 3562 TVTPTPTPTGTQTPTTTPITTTTTVT--------PTPTPTGTQTPTTTPITTTTTVTPTP 3613
Query: 1141 TESSSQKTAVPP 1152
T + +Q P
Sbjct: 3614 TPTGTQTPTTTP 3625
Score = 97.4 bits (241), Expect = 3e-19
Identities = 172/771 (22%), Positives = 259/771 (33%), Gaps = 90/771 (11%)
Query: 2169 PSESATSVPPSDTPS--LTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEI 2226
P + T+V P+ TP+ T + + + TT + +P T T T P+ T +
Sbjct: 1992 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT- 2050
Query: 2227 SSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVA 2286
+ T P + P + ++ T P G + I+ + +V P P P
Sbjct: 2051 PTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPT-PTG 2099
Query: 2287 DTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSS 2346
T I+ V TG T + + TV P +
Sbjct: 2100 TQTPTTTPITTTTTVTPTPTPTGTQT---------------PTTTPITTTTTVTPTPTPT 2144
Query: 2347 VIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPP 2406
P ++TT + T +Q P+ +P ++ P P Q P
Sbjct: 2145 GTQTPTTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2195
Query: 2407 PPPP-------PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-VASPVTTATPLFDA 2458
P P P P P P+ T+ PT P T +P+TT T +
Sbjct: 2196 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2255
Query: 2459 VTTLETTAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
T T + P+T T P P P P++ P T P P+
Sbjct: 2256 PTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2312
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
P TTT PT P PTG T + T +T+ P+PT P + ++P
Sbjct: 2313 TPITTTTTVTPT---PTPTG---TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTP----- 2360
Query: 2576 LTETYVVITLPSEPG--TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPI 2633
+T T V P+ G TPT + + T P +P+ + VT P
Sbjct: 2361 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 2419
Query: 2634 SSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSS 2693
+ QT + T + TP P+ Q PT+ TT V+ T + T + P+ +
Sbjct: 2420 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPIT 2477
Query: 2694 ISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMD 2753
+ T+ P P Q + V T + TT +T
Sbjct: 2478 TTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI----TTTTT 2527
Query: 2754 VKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESL 2813
V T G Q P +VT + TP T T T +T T + T T +
Sbjct: 2528 VTPTPTPT---GTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTT---VTPTPTP 2580
Query: 2814 VGAEHAMTTPLQLTTSKHAEPP---YRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITK 2870
G + TTP+ TT+ P + P+ P GT T IT
Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITT 2639
Query: 2871 PVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMT 2921
TV P G T + T V T +T T +T++ +T
Sbjct: 2640 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2690
Score = 97.4 bits (241), Expect = 3e-19
Identities = 172/771 (22%), Positives = 259/771 (33%), Gaps = 90/771 (11%)
Query: 2169 PSESATSVPPSDTPS--LTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEI 2226
P + T+V P+ TP+ T + + + TT + +P T T T P+ T +
Sbjct: 2199 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT- 2257
Query: 2227 SSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVA 2286
+ T P + P + ++ T P G + I+ + +V P P P
Sbjct: 2258 PTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPT-PTG 2306
Query: 2287 DTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSS 2346
T I+ V TG T + + TV P +
Sbjct: 2307 TQTPTTTPITTTTTVTPTPTPTGTQT---------------PTTTPITTTTTVTPTPTPT 2351
Query: 2347 VIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPP 2406
P ++TT + T +Q P+ +P ++ P P Q P
Sbjct: 2352 GTQTPTTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2402
Query: 2407 PPPP-------PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-VASPVTTATPLFDA 2458
P P P P P P+ T+ PT P T +P+TT T +
Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2462
Query: 2459 VTTLETTAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
T T + P+T T P P P P++ P T P P+
Sbjct: 2463 PTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
P TTT PT P PTG T + T +T+ P+PT P + ++P
Sbjct: 2520 TPITTTTTVTPT---PTPTG---TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTP----- 2567
Query: 2576 LTETYVVITLPSEPG--TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPI 2633
+T T V P+ G TPT + + T P +P+ + VT P
Sbjct: 2568 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 2626
Query: 2634 SSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSS 2693
+ QT + T + TP P+ Q PT+ TT V+ T + T + P+ +
Sbjct: 2627 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPIT 2684
Query: 2694 ISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMD 2753
+ T+ P P Q + V T + TT +T
Sbjct: 2685 TTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI----TTTTT 2734
Query: 2754 VKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESL 2813
V T G Q P +VT + TP T T T +T T + T T +
Sbjct: 2735 VTPTPTPT---GTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTT---VTPTPTP 2787
Query: 2814 VGAEHAMTTPLQLTTSKHAEPP---YRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITK 2870
G + TTP+ TT+ P + P+ P GT T IT
Sbjct: 2788 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITT 2846
Query: 2871 PVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMT 2921
TV P G T + T V T +T T +T++ +T
Sbjct: 2847 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2897
Score = 97.4 bits (241), Expect = 3e-19
Identities = 172/771 (22%), Positives = 259/771 (33%), Gaps = 90/771 (11%)
Query: 2169 PSESATSVPPSDTPS--LTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEI 2226
P + T+V P+ TP+ T + + + TT + +P T T T P+ T +
Sbjct: 2406 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT- 2464
Query: 2227 SSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVA 2286
+ T P + P + ++ T P G + I+ + +V P P P
Sbjct: 2465 PTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPT-PTG 2513
Query: 2287 DTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSS 2346
T I+ V TG T + + TV P +
Sbjct: 2514 TQTPTTTPITTTTTVTPTPTPTGTQT---------------PTTTPITTTTTVTPTPTPT 2558
Query: 2347 VIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPP 2406
P ++TT + T +Q P+ +P ++ P P Q P
Sbjct: 2559 GTQTPTTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2609
Query: 2407 PPPP-------PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-VASPVTTATPLFDA 2458
P P P P P P+ T+ PT P T +P+TT T +
Sbjct: 2610 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2669
Query: 2459 VTTLETTAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
T T + P+T T P P P P++ P T P P+
Sbjct: 2670 PTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
P TTT PT P PTG T + T +T+ P+PT P + ++P
Sbjct: 2727 TPITTTTTVTPT---PTPTG---TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTP----- 2774
Query: 2576 LTETYVVITLPSEPG--TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPI 2633
+T T V P+ G TPT + + T P +P+ + VT P
Sbjct: 2775 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 2833
Query: 2634 SSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSS 2693
+ QT + T + TP P+ Q PT+ TT V+ T + T + P+ +
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPIT 2891
Query: 2694 ISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMD 2753
+ T+ P P Q + V T + TT +T
Sbjct: 2892 TTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI----TTTTT 2941
Query: 2754 VKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESL 2813
V T G Q P +VT + TP T T T +T T + T T +
Sbjct: 2942 VTPTPTPT---GTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTT---VTPTPTP 2994
Query: 2814 VGAEHAMTTPLQLTTSKHAEPP---YRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITK 2870
G + TTP+ TT+ P + P+ P GT T IT
Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITT 3053
Query: 2871 PVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMT 2921
TV P G T + T V T +T T +T++ +T
Sbjct: 3054 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3104
Score = 97.4 bits (241), Expect = 3e-19
Identities = 172/771 (22%), Positives = 259/771 (33%), Gaps = 90/771 (11%)
Query: 2169 PSESATSVPPSDTPS--LTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEI 2226
P + T+V P+ TP+ T + + + TT + +P T T T P+ T +
Sbjct: 2613 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT- 2671
Query: 2227 SSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVA 2286
+ T P + P + ++ T P G + I+ + +V P P P
Sbjct: 2672 PTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPT-PTG 2720
Query: 2287 DTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSS 2346
T I+ V TG T + + TV P +
Sbjct: 2721 TQTPTTTPITTTTTVTPTPTPTGTQT---------------PTTTPITTTTTVTPTPTPT 2765
Query: 2347 VIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPP 2406
P ++TT + T +Q P+ +P ++ P P Q P
Sbjct: 2766 GTQTPTTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2816
Query: 2407 PPPP-------PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-VASPVTTATPLFDA 2458
P P P P P P+ T+ PT P T +P+TT T +
Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2876
Query: 2459 VTTLETTAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
T T + P+T T P P P P++ P T P P+
Sbjct: 2877 PTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
P TTT PT P PTG T + T +T+ P+PT P + ++P
Sbjct: 2934 TPITTTTTVTPT---PTPTG---TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTP----- 2981
Query: 2576 LTETYVVITLPSEPG--TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPI 2633
+T T V P+ G TPT + + T P +P+ + VT P
Sbjct: 2982 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 3040
Query: 2634 SSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSS 2693
+ QT + T + TP P+ Q PT+ TT V+ T + T + P+ +
Sbjct: 3041 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPIT 3098
Query: 2694 ISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMD 2753
+ T+ P P Q + V T + TT +T
Sbjct: 3099 TTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI----TTTTT 3148
Query: 2754 VKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESL 2813
V T G Q P +VT + TP T T T +T T + T T +
Sbjct: 3149 VTPTPTPT---GTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTT---VTPTPTP 3201
Query: 2814 VGAEHAMTTPLQLTTSKHAEPP---YRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITK 2870
G + TTP+ TT+ P + P+ P GT T IT
Sbjct: 3202 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITT 3260
Query: 2871 PVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMT 2921
TV P G T + T V T +T T +T++ +T
Sbjct: 3261 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3311
Score = 97.4 bits (241), Expect = 3e-19
Identities = 172/771 (22%), Positives = 259/771 (33%), Gaps = 90/771 (11%)
Query: 2169 PSESATSVPPSDTPS--LTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEI 2226
P + T+V P+ TP+ T + + + TT + +P T T T P+ T +
Sbjct: 2820 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT- 2878
Query: 2227 SSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVA 2286
+ T P + P + ++ T P G + I+ + +V P P P
Sbjct: 2879 PTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPT-PTG 2927
Query: 2287 DTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSS 2346
T I+ V TG T + + TV P +
Sbjct: 2928 TQTPTTTPITTTTTVTPTPTPTGTQT---------------PTTTPITTTTTVTPTPTPT 2972
Query: 2347 VIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPP 2406
P ++TT + T +Q P+ +P ++ P P Q P
Sbjct: 2973 GTQTPTTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3023
Query: 2407 PPPP-------PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-VASPVTTATPLFDA 2458
P P P P P P+ T+ PT P T +P+TT T +
Sbjct: 3024 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3083
Query: 2459 VTTLETTAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
T T + P+T T P P P P++ P T P P+
Sbjct: 3084 PTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3140
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
P TTT PT P PTG T + T +T+ P+PT P + ++P
Sbjct: 3141 TPITTTTTVTPT---PTPTG---TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTP----- 3188
Query: 2576 LTETYVVITLPSEPG--TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPI 2633
+T T V P+ G TPT + + T P +P+ + VT P
Sbjct: 3189 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 3247
Query: 2634 SSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSS 2693
+ QT + T + TP P+ Q PT+ TT V+ T + T + P+ +
Sbjct: 3248 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPIT 3305
Query: 2694 ISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMD 2753
+ T+ P P Q + V T + TT +T
Sbjct: 3306 TTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI----TTTTT 3355
Query: 2754 VKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESL 2813
V T G Q P +VT + TP T T T +T T + T T +
Sbjct: 3356 VTPTPTPT---GTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTT---VTPTPTP 3408
Query: 2814 VGAEHAMTTPLQLTTSKHAEPP---YRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITK 2870
G + TTP+ TT+ P + P+ P GT T IT
Sbjct: 3409 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITT 3467
Query: 2871 PVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMT 2921
TV P G T + T V T +T T +T++ +T
Sbjct: 3468 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3518
Score = 97.4 bits (241), Expect = 3e-19
Identities = 172/771 (22%), Positives = 259/771 (33%), Gaps = 90/771 (11%)
Query: 2169 PSESATSVPPSDTPS--LTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEI 2226
P + T+V P+ TP+ T + + + TT + +P T T T P+ T +
Sbjct: 3027 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT- 3085
Query: 2227 SSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVA 2286
+ T P + P + ++ T P G + I+ + +V P P P
Sbjct: 3086 PTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPT-PTG 3134
Query: 2287 DTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSS 2346
T I+ V TG T + + TV P +
Sbjct: 3135 TQTPTTTPITTTTTVTPTPTPTGTQT---------------PTTTPITTTTTVTPTPTPT 3179
Query: 2347 VIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPP 2406
P ++TT + T +Q P+ +P ++ P P Q P
Sbjct: 3180 GTQTPTTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3230
Query: 2407 PPPP-------PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-VASPVTTATPLFDA 2458
P P P P P P+ T+ PT P T +P+TT T +
Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3290
Query: 2459 VTTLETTAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
T T + P+T T P P P P++ P T P P+
Sbjct: 3291 PTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
P TTT PT P PTG T + T +T+ P+PT P + ++P
Sbjct: 3348 TPITTTTTVTPT---PTPTG---TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTP----- 3395
Query: 2576 LTETYVVITLPSEPG--TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPI 2633
+T T V P+ G TPT + + T P +P+ + VT P
Sbjct: 3396 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 3454
Query: 2634 SSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSS 2693
+ QT + T + TP P+ Q PT+ TT V+ T + T + P+ +
Sbjct: 3455 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPIT 3512
Query: 2694 ISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMD 2753
+ T+ P P Q + V T + TT +T
Sbjct: 3513 TTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI----TTTTT 3562
Query: 2754 VKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESL 2813
V T G Q P +VT + TP T T T +T T + T T +
Sbjct: 3563 VTPTPTPT---GTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTT---VTPTPTP 3615
Query: 2814 VGAEHAMTTPLQLTTSKHAEPP---YRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITK 2870
G + TTP+ TT+ P + P+ P GT T IT
Sbjct: 3616 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITT 3674
Query: 2871 PVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMT 2921
TV P G T + T V T +T T +T++ +T
Sbjct: 3675 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3725
Score = 97.4 bits (241), Expect = 3e-19
Identities = 172/771 (22%), Positives = 259/771 (33%), Gaps = 90/771 (11%)
Query: 2169 PSESATSVPPSDTPS--LTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEI 2226
P + T+V P+ TP+ T + + + TT + +P T T T P+ T +
Sbjct: 3234 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT- 3292
Query: 2227 SSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVA 2286
+ T P + P + ++ T P G + I+ + +V P P P
Sbjct: 3293 PTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPT-PTG 3341
Query: 2287 DTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSS 2346
T I+ V TG T + + TV P +
Sbjct: 3342 TQTPTTTPITTTTTVTPTPTPTGTQT---------------PTTTPITTTTTVTPTPTPT 3386
Query: 2347 VIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPP 2406
P ++TT + T +Q P+ +P ++ P P Q P
Sbjct: 3387 GTQTPTTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3437
Query: 2407 PPPP-------PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-VASPVTTATPLFDA 2458
P P P P P P+ T+ PT P T +P+TT T +
Sbjct: 3438 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3497
Query: 2459 VTTLETTAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
T T + P+T T P P P P++ P T P P+
Sbjct: 3498 PTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3554
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
P TTT PT P PTG T + T +T+ P+PT P + ++P
Sbjct: 3555 TPITTTTTVTPT---PTPTG---TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTP----- 3602
Query: 2576 LTETYVVITLPSEPG--TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPI 2633
+T T V P+ G TPT + + T P +P+ + VT P
Sbjct: 3603 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 3661
Query: 2634 SSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSS 2693
+ QT + T + TP P+ Q PT+ TT V+ T + T + P+ +
Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPIT 3719
Query: 2694 ISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMD 2753
+ T+ P P Q + V T + TT +T
Sbjct: 3720 TTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI----TTTTT 3769
Query: 2754 VKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESL 2813
V T G Q P +VT + TP T T T +T T + T T +
Sbjct: 3770 VTPTPTPT---GTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTT---VTPTPTP 3822
Query: 2814 VGAEHAMTTPLQLTTSKHAEPP---YRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITK 2870
G + TTP+ TT+ P + P+ P GT T IT
Sbjct: 3823 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITT 3881
Query: 2871 PVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMT 2921
TV P G T + T V T +T T +T++ +T
Sbjct: 3882 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3932
Score = 97.4 bits (241), Expect = 3e-19
Identities = 172/771 (22%), Positives = 259/771 (33%), Gaps = 90/771 (11%)
Query: 2169 PSESATSVPPSDTPS--LTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEI 2226
P + T+V P+ TP+ T + + + TT + +P T T T P+ T +
Sbjct: 3441 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT- 3499
Query: 2227 SSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVA 2286
+ T P + P + ++ T P G + I+ + +V P P P
Sbjct: 3500 PTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPT-PTG 3548
Query: 2287 DTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSS 2346
T I+ V TG T + + TV P +
Sbjct: 3549 TQTPTTTPITTTTTVTPTPTPTGTQT---------------PTTTPITTTTTVTPTPTPT 3593
Query: 2347 VIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPP 2406
P ++TT + T +Q P+ +P ++ P P Q P
Sbjct: 3594 GTQTPTTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3644
Query: 2407 PPPP-------PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-VASPVTTATPLFDA 2458
P P P P P P+ T+ PT P T +P+TT T +
Sbjct: 3645 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3704
Query: 2459 VTTLETTAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
T T + P+T T P P P P++ P T P P+
Sbjct: 3705 PTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3761
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
P TTT PT P PTG T + T +T+ P+PT P + ++P
Sbjct: 3762 TPITTTTTVTPT---PTPTG---TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTP----- 3809
Query: 2576 LTETYVVITLPSEPG--TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPI 2633
+T T V P+ G TPT + + T P +P+ + VT P
Sbjct: 3810 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 3868
Query: 2634 SSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSS 2693
+ QT + T + TP P+ Q PT+ TT V+ T + T + P+ +
Sbjct: 3869 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPIT 3926
Query: 2694 ISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMD 2753
+ T+ P P Q + V T + TT +T
Sbjct: 3927 TTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI----TTTTT 3976
Query: 2754 VKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESL 2813
V T G Q P +VT + TP T T T +T T + T T +
Sbjct: 3977 VTPTPTPT---GTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTT---VTPTPTP 4029
Query: 2814 VGAEHAMTTPLQLTTSKHAEPP---YRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITK 2870
G + TTP+ TT+ P + P+ P GT T IT
Sbjct: 4030 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITT 4088
Query: 2871 PVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMT 2921
TV P G T + T V T +T T +T++ +T
Sbjct: 4089 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4139
Score = 95.9 bits (237), Expect = 9e-19
Identities = 86/315 (27%), Positives = 116/315 (36%), Gaps = 26/315 (8%)
Query: 2399 LDISAQPPPPPPPPPPPPP------PPPPPPPPPLPPPTSPKPTILPKKKLTVAS---PV 2449
+D P PP P PPP PP P PP T+P PT P +T + P
Sbjct: 1392 MDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPT 1451
Query: 2450 TTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPP 2509
TT +P TT T P T +PP P P P+ T P + P
Sbjct: 1452 TTPSPPISTTTTPPPTTT------PSPPTTTPSPPTTTPSP---PTTTTTTPPPTTTPSP 1502
Query: 2510 IAPKPVIPQLPTTTQKPTDIHPKPTGLSLT--SSMTLNLVTSADYKLPSPTSPLSPHSNK 2567
P+ P TTT PT PT + T + T + T+ P+ T+ L P +
Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1562
Query: 2568 SSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVT 2627
S P + T T T PS P T T S + T+ P P+ + PP T
Sbjct: 1563 SPP---PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPP---PTTTPSPPTTTTTTPPPTT 1616
Query: 2628 AVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAP 2687
P ++ T S + TP P++ P + T T + + T +T P
Sbjct: 1617 TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPP 1676
Query: 2688 SVGLSSISITIPPEP 2702
S IT P P
Sbjct: 1677 PTTTPSSPITTTPSP 1691
Score = 95.5 bits (236), Expect = 1e-18
Identities = 195/904 (21%), Positives = 297/904 (32%), Gaps = 95/904 (10%)
Query: 2077 TPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHF 2136
T S PT PI + +T+ P T++ + T S + T P + T
Sbjct: 1616 TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTP 1675
Query: 2137 STEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSL--TSSVSSVCTT 2194
+T + S T S P + T+ + TPS T+ + TT
Sbjct: 1676 PPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTT 1735
Query: 2195 DSSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSL------- 2247
S P TT+ ++ T T S I+ T+ P S P V L
Sbjct: 1736 TPSPPTTTMTTLPPTTTSSPLTTTPLPPS--ITPPTFSPFSTTT-PTTPCVPLCNWTGWL 1792
Query: 2248 DRTAPPDGRASADHIVISL---SDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKA 2304
D P + D +I A++I P+ P+ T + + K
Sbjct: 1793 DSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKN 1852
Query: 2305 KKETGNGII-----------LEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIA---L 2350
+ + G+I ++ E + T++ T ++ +
Sbjct: 1853 EDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPT 1912
Query: 2351 PMKEQLSTTYFTSGETFGQEKPA---SQLPSGSPSVSSLPAKPRPFFR----------SS 2397
P Q TT + T P +Q P+ +P ++ P P ++
Sbjct: 1913 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1972
Query: 2398 SLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPK-PTILPKKKLTVASPVTTAT--- 2453
+ ++ P P P P P P PT + PT P T +P T T
Sbjct: 1973 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2032
Query: 2454 -PLFDAVTTLET-------TAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHR 2502
P +TT T T P+T T P P P P++ P T
Sbjct: 2033 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2092
Query: 2503 PEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLS 2562
P P+ P TTT PT P PTG T + T +T+ P+PT P
Sbjct: 2093 PTPTPTGTQTPTTTPITTTTTVTPT---PTPTG---TQTPTTTPITTTTTVTPTPT-PTG 2145
Query: 2563 PHSNKSSPRFSKSLTETYVVITLPSEPG--TPTDSSASQAITSWPLGSPSKDLVSVEPVF 2620
+ ++P +T T V P+ G TPT + + T P +P+
Sbjct: 2146 TQTPTTTP-----ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2200
Query: 2621 SVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVS 2680
+ VT P + QT + T + TP P+ Q PT+ TT V+ T +
Sbjct: 2201 TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP-T 2257
Query: 2681 ATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKT 2740
T + P+ + + T+ P P Q + V T + T
Sbjct: 2258 PTGTQTPTTTPITTTTTVTPTPTPTGT------QTPTTTPITTTTTVTPTPTPTGTQTPT 2311
Query: 2741 TDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTC 2800
T +T V T G Q P +VT + TP T T T +T
Sbjct: 2312 TTPI----TTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITT 2363
Query: 2801 TASASYTTGTESLVGAEHAMTTPLQLTTSKHAEPP---YRIPSDQVFPIAREEAPINLSL 2857
T + T T + G + TTP+ TT+ P + P+ P
Sbjct: 2364 TTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2420
Query: 2858 GTPAHAVTLAITKPVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTS 2917
GT T IT TV P G T + T V T +T T +T+
Sbjct: 2421 GTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2479
Query: 2918 SVMT 2921
+ +T
Sbjct: 2480 TTVT 2483
Score = 84.0 bits (206), Expect = 4e-15
Identities = 169/784 (21%), Positives = 254/784 (32%), Gaps = 117/784 (14%)
Query: 2169 PSESATSVPPSDTPS--LTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEI 2226
P + T+V P+ TP+ T + + + TT + +P T T T P+ T +
Sbjct: 3648 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT- 3706
Query: 2227 SSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVA 2286
+ T P + P + ++ T P G + I+ + +V P P P
Sbjct: 3707 PTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTT-------TVTPTPT-PTG 3755
Query: 2287 DTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSS 2346
T I+ V TG T + + TV P +
Sbjct: 3756 TQTPTTTPITTTTTVTPTPTPTGTQT---------------PTTTPITTTTTVTPTPTPT 3800
Query: 2347 VIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPP 2406
P ++TT + T +Q P+ +P ++ P P Q P
Sbjct: 3801 GTQTPTTTPITTT---TTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3851
Query: 2407 PPPP-------PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT-VASPVTTATPLFDA 2458
P P P P P P+ T+ PT P T +P+TT T +
Sbjct: 3852 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3911
Query: 2459 VTTLETTAVLRSNGLPVTRICTTAPPPVPP---KPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
T T + P+T T P P P P++ P T P P+
Sbjct: 3912 PTPTGTQTPTTT---PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3968
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
P TTT PT P PTG T + T +T+ P+PT P + ++P
Sbjct: 3969 TPITTTTTVTPT---PTPTG---TQTPTTTPITTTTTVTPTPT-PTGTQTPTTTP----- 4016
Query: 2576 LTETYVVITLPSEPG--TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPI 2633
+T T V P+ G TPT + + T P +P+ + VT P
Sbjct: 4017 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP- 4075
Query: 2634 SSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSS 2693
+ QT + T + TP P+ Q PT+ TT V+ T + T + P+ +
Sbjct: 4076 TGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTP-TPTGTQTPTTTPIT 4133
Query: 2694 ISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMD 2753
+ T+ P P +T + TT T
Sbjct: 4134 TTTTVTPTPTPTGT-----------------------QTPTTTPITTTTTVTPTPTPT-- 4168
Query: 2754 VKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGT--- 2810
G Q P +VT + TP T T + A TT
Sbjct: 4169 -----------GTQTPTTTPITTTTTVTPT-PTPTGTQTGPPTHTSTAPIAELTTSNPPP 4216
Query: 2811 -ESLVGAEHAMTTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAIT 2869
S + ++PL +T+ + P I P + AP S G T
Sbjct: 4217 ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTT 4276
Query: 2870 KPVTVPPVGVTNGW----TDSTVSQGITDG---EVVDLSTTKSHRTVVTMDESTSSVMTK 2922
P P G T G T STV T LST RT +S ++
Sbjct: 4277 SPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICC 4336
Query: 2923 IIED 2926
++ D
Sbjct: 4337 VLND 4340
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 1903 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 1960
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 1961 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 2008
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 2009 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2044
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 1995 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 2052
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 2053 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 2100
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 2101 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2136
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 2087 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 2144
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 2145 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 2192
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 2193 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2228
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 2179 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 2236
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 2237 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 2284
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 2285 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2320
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 2328
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 2329 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 2376
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 2377 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2412
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 2363 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 2420
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 2421 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 2468
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 2469 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2504
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 2455 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 2512
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 2513 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 2560
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 2561 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2596
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 2604
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 2605 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 2652
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 2653 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 2696
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 2697 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 2744
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 2745 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2780
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 2788
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 2789 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 2836
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 2837 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2872
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 2880
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 2881 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 2928
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 2929 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2964
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 2972
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 2973 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 3020
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 3021 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3056
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 3064
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 3065 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 3112
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 3113 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3148
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 3156
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 3157 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 3204
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 3205 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3240
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 3248
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 3249 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 3296
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 3297 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3332
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 3283 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 3340
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 3341 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 3388
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 3389 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3424
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 3432
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 3433 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 3480
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 3481 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3516
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 3467 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 3524
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 3525 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 3572
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 3573 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3608
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 3616
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 3617 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 3664
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 3665 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3700
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 3708
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 3709 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 3756
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 3757 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3792
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 3743 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 3800
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 3801 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 3848
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 3849 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3884
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 3835 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 3892
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 3893 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 3940
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 3941 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3976
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 3927 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 3984
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 3985 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 4032
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 4033 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4068
Score = 37.7 bits (86), Expect = 0.30
Identities = 41/158 (25%), Positives = 57/158 (36%), Gaps = 17/158 (10%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T +P PT
Sbjct: 4019 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT-PTPT 4076
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQ-PTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV 3958
T + T +P TQ PT + T T V PTPTP +
Sbjct: 4077 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGT--------- 4124
Query: 3959 IQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNT 3996
Q P T + +T Q P++T T
Sbjct: 4125 --QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4160
Score = 37.0 bits (84), Expect = 0.51
Identities = 40/186 (21%), Positives = 62/186 (33%), Gaps = 22/186 (11%)
Query: 3575 TQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKV-LYSPISPLSPG 3633
T SP ++ T+PP P +T P P +P +PI+P +
Sbjct: 1585 TPSPPTITTTTPPPTTTPSPP------------TTTTTTPPPTTTPSPPTTTPITPPTST 1632
Query: 3634 KALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESS 3693
L P P P P+ P T + + P P + + +
Sbjct: 1633 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPIT------TTTTPPPTTTPSSPIT 1686
Query: 3694 RAPFQYTEGYTTKGSQTMTSSGAQKKV---KRTLPNPPPEEISTGTQSTFSTMGTVSRRR 3750
P T TT T SS T P+PPP ++T + +T + T +
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT 1746
Query: 3751 ICRTNT 3756
+ T T
Sbjct: 1747 LPPTTT 1752
Score = 36.6 bits (83), Expect = 0.66
Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 6/110 (5%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T ++ PT
Sbjct: 4065 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITT---TTTVTPTPT 4120
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPS 3949
PT Q+ V+P T Q T T TPTP P+
Sbjct: 4121 PTG--TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4168
Score = 36.6 bits (83), Expect = 0.66
Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 6/110 (5%)
Query: 3840 SSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
++T T + G + P T P T + P T T +Q P T+P T ++ PT
Sbjct: 4088 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITT---TTTVTPTPT 4143
Query: 3900 PTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPS 3949
PT Q+ V+P T Q T T TPTP P+
Sbjct: 4144 PTG--TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4191
Score = 33.9 bits (76), Expect = 4.3
Identities = 47/172 (27%), Positives = 61/172 (35%), Gaps = 25/172 (14%)
Query: 3569 TEADSDTQSPQYLSATSPPKDKKRPTPL--EIGYSSHLRADSTVQLAPS--PPKS--PKV 3622
T + TQ+P T+ PTP + G +H +L S PP+S P+
Sbjct: 4164 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQT 4223
Query: 3623 LYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDP 3682
S SPL+ L S LP I +M P S TA + S
Sbjct: 4224 SRSTSSPLTESTTLLST-------LPPAI--------EMTSTAPPSTPTAPT---TTSGG 4265
Query: 3683 KPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEIST 3734
LSP ++ P T G TT S T S Q P P +ST
Sbjct: 4266 HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAW-TPTPTPLST 4316
Score = 33.1 bits (74), Expect = 7.3
Identities = 35/126 (27%), Positives = 44/126 (34%), Gaps = 10/126 (7%)
Query: 3856 PRTAPQTEFSQFIPPQTQTESQLVPPT---SPYTQYQYSSPALPTQAPTSYTQQSHFEQQ 3912
P T P + PP T T + PPT SP T + PA T P + T
Sbjct: 1473 PTTTPSPPTTTPSPPTTTTTTP--PPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTT 1530
Query: 3913 TLYHQQV--SPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQKPRQTTLYL 3970
T SP T P +T + P P+P P + P P TT
Sbjct: 1531 TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP---TTTPSPPTTTTPS 1587
Query: 3971 EPKITS 3976
P IT+
Sbjct: 1588 PPTITT 1593
Score = 32.7 bits (73), Expect = 9.6
Identities = 37/150 (24%), Positives = 52/150 (34%), Gaps = 16/150 (10%)
Query: 3039 SSKTTGPYPETRQVISGAGISTPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTP 3098
S TT P P T + +TP T PP ++ TP+P
Sbjct: 1478 SPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP------------ASTTTLPPTTTPSP 1525
Query: 3099 STFAITTQPGSIFSTTVRDLSGIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTG 3158
T TT P + + + + I + T+LP P P + TT T
Sbjct: 1526 PTTTTTTPPPTT-TPSPPTTTPITPPTSTTTLPPTTTPSPPPTT---TTTPPPTTTPSPP 1581
Query: 3159 IDISASLQTITMESLTAETIDSVPTLTTAS 3188
+ S TIT + T S PT TT +
Sbjct: 1582 TTTTPSPPTITTTTPPPTTTPSPPTTTTTT 1611
Score = 32.7 bits (73), Expect = 9.6
Identities = 33/125 (26%), Positives = 38/125 (30%), Gaps = 8/125 (6%)
Query: 3869 PPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQV---SPYQTQ 3925
PP T T SP T S P + T P T S T SP T
Sbjct: 1565 PPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1624
Query: 3926 PTFQAVATMSFTPQVQPTPTP-----QPSYQLPSQMMVIQQKPRQTTLYLEPKITSNYEV 3980
P +T + P P+P P P PS P TT P T+
Sbjct: 1625 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSP 1684
Query: 3981 IRNQP 3985
I P
Sbjct: 1685 ITTTP 1689
>gi|154354981 regulating synaptic membrane exocytosis 2 isoform b
[Homo sapiens]
Length = 1163
Score = 137 bits (345), Expect = 3e-31
Identities = 112/375 (29%), Positives = 174/375 (46%), Gaps = 85/375 (22%)
Query: 4496 RIKITRDSKDHTV---SGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEG 4552
RI + + KD +V SG LG+++VGGK SG + A+I K+ G A+ G L G
Sbjct: 389 RILLNKRLKDGSVPRDSGAMLGLKVVGGKMT--ESGRLCAFITKVKKGSLADTVGHLRPG 446
Query: 4553 MQVLEWNGIPLTSKTYEEVQSII--SQQSGEAEICVRLDLNMLSDSENSQHLELHEPPKA 4610
+VLEWNG L T+EEV +II S+ + E+ V + + +S H +L +
Sbjct: 447 DEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPIGDIPRIPDSTHAQLESSSSS 506
Query: 4611 VDKAKSPGVDPKQLAAELQKVSLQQSPLVLSSVVEKGSHVHSGPTSAGSSSVPSPGQPGS 4670
+ K S SV SP PG
Sbjct: 507 FESQKM---------------------------------------DRPSISVTSPMSPGM 527
Query: 4671 PSVSKKKHGSSKPTDGTKVVSHPITGEIQLQINYD-LGN-LIIHILQARNLVPRDNNGYS 4728
+ V ++G++ +++ +D +G+ LI+ IL A++L R++
Sbjct: 528 ----------------LRDVPQFLSGQLSIKLWFDKVGHQLIVTILGAKDLPSREDGRPR 571
Query: 4729 DPFVKVYLLPGRGQVMVVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLE 4788
+P+VK+Y LP R S + KRRTK V+K+L P+WNQT IY + + +++ LE
Sbjct: 572 NPYVKIYFLPDR---------SDKNKRRTKTVKKTLEPKWNQTFIYSPVHRREFRERMLE 622
Query: 4789 VTVWDYDRF--SSNDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSQSSQQS 4846
+T+WD R ++FLGE+LI+L T+ LD+ P WY L QT + S
Sbjct: 623 ITLWDQARVREEESEFLGEILIEL-ETALLDDEPHWYKL--QTHDV-------SSLPLPH 672
Query: 4847 PKPSVIKSRSHGIFP 4861
P P + + + HG P
Sbjct: 673 PSPYMPRRQLHGESP 687
Score = 82.0 bits (201), Expect = 1e-14
Identities = 95/336 (28%), Positives = 146/336 (43%), Gaps = 54/336 (16%)
Query: 4830 ESIDHGKSHSSQSSQQSPKPSVIKSRSHGIF-PDPSKDMQVPTIEKSHSSPGSSKSSSEG 4888
E+ D H S+S++Q P +RS PD + +P++ S+P S + S
Sbjct: 832 EAADRQPYHRSRSTEQRPLLERTTTRSRSTERPDTNLMRSMPSLMTGRSAP-PSPALSRS 890
Query: 4889 HLRSHGPSRSQSKTSVTQTHLEDAGAAIAAAEAAVQQLRIQPTKPPNHRPAESSVSTGSS 4948
H R+ S S T V A +QL P K R A +
Sbjct: 891 HPRTGSVQTSPSSTPV--------------AGRRGRQLPQLPPKGTLDRKAGGKKLRSTV 936
Query: 4949 GSSFGSGYSVD-------------SEGS-SSTAGETNL-FPIPRIGKMGQ-----NGQEP 4988
S +G +V+ ++GS +S + E NL FP R+ Q +G P
Sbjct: 937 QRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQFSDFLDGLGP 996
Query: 4989 VKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPD 5048
+ G T MG+I++ + M G QL VEI++ R + K S LP
Sbjct: 997 AQLVG------RQTLATPAMGDIQVGM---MDKKG-QLEVEIIRARGLVVKPGSKT-LPA 1045
Query: 5049 LYVKIYVMNISTQKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILLFSNGGKFMK 5108
YVK+Y+++ + KKKT+V R EP + + F SP G LQI+++ + G+
Sbjct: 1046 PYVKVYLLDNGVC--IAKKKTKVARKTLEPLYQQLLSFEESPQGKVLQIIVWGDYGRMDH 1103
Query: 5109 KTLIGEACIWLDKVDLRKRIVNWHKL-----LVSPT 5139
K+ +G A I LD+++L ++ W KL LV PT
Sbjct: 1104 KSFMGVAQILLDELELSNMVIGWFKLFPPSSLVDPT 1139
Score = 57.0 bits (136), Expect = 5e-07
Identities = 50/176 (28%), Positives = 82/176 (46%), Gaps = 20/176 (11%)
Query: 4686 GTKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNG-YSDPFVKVYLLPGRGQVM 4744
G + ++ P G+IQ+ + G L + I++AR LV + + P+VKVYLL
Sbjct: 1001 GRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPYVKVYLL------- 1053
Query: 4745 VVQNASAEYKRRTKHVQKSLNPEWNQTVIYKSISMEQLKKKTLEVTVW-DYDRFSSNDFL 4803
N K++TK +K+L P + Q + ++ E + K L++ VW DY R F+
Sbjct: 1054 --DNGVCIAKKKTKVARKTLEPLYQQLLSFE----ESPQGKVLQIIVWGDYGRMDHKSFM 1107
Query: 4804 GEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKS----HSSQSS-QQSPKPSVIKS 4854
G I L + W+ L + +D + +SQSS + S PS +S
Sbjct: 1108 GVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS 1163
Score = 35.8 bits (81), Expect = 1.1
Identities = 23/76 (30%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 5012 KIALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPDLYVKIYVMNISTQKKVIKKKTRV 5071
++++K G QLIV IL +++ + P YVKIY + + K K++T+
Sbjct: 538 QLSIKLWFDKVGHQLIVTILGAKDLPSREDGRPRNP--YVKIYFLPDRSDKN--KRRTKT 593
Query: 5072 CRHDREPSFNETFRFS 5087
+ EP +N+TF +S
Sbjct: 594 VKKTLEPKWNQTFIYS 609
Score = 32.7 bits (73), Expect = 9.6
Identities = 41/204 (20%), Positives = 76/204 (37%), Gaps = 14/204 (6%)
Query: 3408 KQPKKRSSGAKVRGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKS 3467
+ +R + R +Y + T PRS D Q + + D ++S R ++S
Sbjct: 49 RDQNRRYDQREEREEYSQYATSDTAMPRSPSDYADRRSQHEPQFYEDSDHLSYRDSNRRS 108
Query: 3468 VDTSVQ--TDDEDQDEWDMPTRSRRKARV-GKYGDSMTEAD---KTKPLSKVSSIAVQTV 3521
S + DDED + D R RR+ +Y A K +P + I +
Sbjct: 109 HRHSKEYIVDDEDVESRDEYERQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVS 168
Query: 3522 --------AEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADS 3573
+++S+ + R +R ++ I A + + S+ EA
Sbjct: 169 RARHERRHSDVSLANADLEDSRISMLRMDRPSRQRSISERRAAMENQRSYSMERTREAQG 228
Query: 3574 DTQSPQYLSATSPPKDKKRPTPLE 3597
+ Q + SPP ++ P P++
Sbjct: 229 PSSYAQRTTNHSPPTPRRSPLPID 252
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 135 bits (340), Expect = 1e-30
Identities = 281/1312 (21%), Positives = 463/1312 (35%), Gaps = 198/1312 (15%)
Query: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ--QP 425
P+ PAQ S + E P KA P VG Q G A PP ++ P+ ++ +
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE 275
Query: 426 GLQSPAKAPGPTKTPVQQ-----------------PGPGKIPAQQAGPGKTSAQ-QTGPT 467
G +S +AP T++ V+ PG G PA G ++Q + G
Sbjct: 276 GSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 468 KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527
+ S+ ++ PA Q ++ SQ ++ P + P +P PG T
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGA-APAPPGKT 394
Query: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL--- 584
P + + K S ++ S + P SGK Q S AK+ P +G
Sbjct: 395 GPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 585 -PKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMK 643
P+ P ++ + E+ + ++ E + +L N +VK L + Q+K
Sbjct: 455 PPRKTGPAA--AQVQVGKQEEDSRSSSEESDSDREALAAMNA----AQVKP-LGKSPQVK 507
Query: 644 RALGGDLAPVP--SSPQPKLKTAPVTTTSAVSK----SSPQPQQTSPKKDA------APK 691
A + P+ + P P K P T ++ V K S +++S D AP
Sbjct: 508 PASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA 567
Query: 692 QDLS--------------KAPEPKKPPPLVK----------QPTLHGSPSAKAKQPPEAD 727
Q+ S K P K P V+ + + S SA +++ P A
Sbjct: 568 QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAM 627
Query: 728 SLSKPAP----------PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA----T 773
+ ++ P PK+ + + APV + P+ T SS A T
Sbjct: 628 TAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT-QAPRKAGTATSPAGSSPAVAGGT 686
Query: 774 TKP--DIPSSKVQSQAEEKTTPPLKTDSAKP--------SQSFPPTGE-----------K 812
+P D SS+ EEKT + AK + S P G K
Sbjct: 687 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 746
Query: 813 VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872
P ++ DS+ S E+ P Q K KK Q K +P P
Sbjct: 747 TGPTVTQVKAEKQEDSESSEEESDSEEAAAS----PAQVKTSVKKTQAKANPAAARAPSA 802
Query: 873 KGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT------TPQET 926
KG+ + PG TA Q+SP + R N + P S P+ T +
Sbjct: 803 KGTISAPGKVVTAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQA 860
Query: 927 VTGKLFGFGASIF-SQASNLISTAGQPGP----HSQSGPGAPMKQAPAPSQPPTSQGPPK 981
TG G+S S + T Q P H AP K++P PT PP
Sbjct: 861 QTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT---PPG 917
Query: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----PPIKDSKSLT 1037
TG P+ + K++ ++E+ + E V + K P P +
Sbjct: 918 KTG-----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 972
Query: 1038 AEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPH 1097
A P +A + K+ EST +E P + V + PT H
Sbjct: 973 ATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM----PTAH 1028
Query: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMP-PAPSGPKASPMPVPTESSSQKTAVPPQVKL 1156
I + + S ++ D +K PA K +P +P ++ K K
Sbjct: 1029 -PRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQ---KA 1084
Query: 1157 VKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE 1216
+ Q +T+ + V ++ P T+ Q + +KL K K +Q+ PE
Sbjct: 1085 SEAQPPVARTQPSSGVDSAVG---TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPE 1141
Query: 1217 EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKL 1276
++ S + EE P+ K A T P + + L + AE
Sbjct: 1142 SS-----DDSEDSSDSSSGSEEDGEGPQGAK---SAHTLGPTPSRTETLVEETA-AESSE 1192
Query: 1277 EGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDK----TTKTIKEQPQPPCTAKPDQV 1332
+ VAP + S ++ PK D +T K+ P AKP Q
Sbjct: 1193 DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA 1252
Query: 1333 EPG-KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE--IPSLIPTDEKDIL 1389
KT ++ S T+ + K +G + S+ + S++ + + P +E +
Sbjct: 1253 AGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQ 1312
Query: 1390 KGLKK--------------DSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKK 1435
+ K D+ + S S KL + A+ K +KK
Sbjct: 1313 ASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG------DQPAARTPRSKKKKK 1366
Query: 1436 TQPHE-----VSPEQPKDQEKTQSLSETLEITISEEEIKES------QEERKDTFKKD-- 1482
E VSPE+ K ++ + + E++ K S ++E ++ +K
Sbjct: 1367 LGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMG 1426
Query: 1483 ----SQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRR 1530
Q P SK K+KS+ ++E +++S ++ Q+K++
Sbjct: 1427 TVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKK 1478
Score = 121 bits (304), Expect = 2e-26
Identities = 323/1467 (22%), Positives = 510/1467 (34%), Gaps = 231/1467 (15%)
Query: 46 SQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPS-MHRKQELDSSHPPKQSGRPPDPGR 104
S+ SEEE A L + A+ PS M K + ++ K P P
Sbjct: 85 SESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP-- 142
Query: 105 PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALS 164
+ +T L G+SP S + S + T + E + +P F +
Sbjct: 143 ------ATGKTVANL-----LSGKSPRK-SAEPSANTTLVSETEEEGSVPAF-----GAA 185
Query: 165 AVSSVVNKFNPFDLISDSEASQEETTKKQKV-VQKEQGKPEGIIKPPLQQQPPKPIPKQQ 223
A +V+ D+ +S +ET + K V+ Q K + + P P +
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
Query: 224 GPGRDPLQQDGTPKSISSQQPEK-IKSQPPGTGKPIQGPTQTPQTDHA--KLPLQRDASR 280
G ++ P + +++PE+ +S G+ + P T A K+ R AS
Sbjct: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305
Query: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPA------ 333
P A G+ P+ P + Q GKP + E+S + PA
Sbjct: 306 P----AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQ 361
Query: 334 --------QPSGLTKPLAQQPGTVKPPVQPPGTTKPP-AQPLGPAKPPAQQTGSEKPSSE 384
Q + P + P P PPG T P A+ + Q+ SE+ SE
Sbjct: 362 AKASGKTSQVGAASAPAKESPRKGAAPA-PPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ--------QPGLQSPAKAPGP 436
+ P A A+P G PAK ++ P P + Q G Q
Sbjct: 421 EEAP-AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 479
Query: 437 TKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKP-PPQQPGPAKPPPQ-- 492
++ + + A Q P GK+ + T L A P PP + GPA P Q
Sbjct: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539
Query: 493 ---QPGSAKPPSQQPGSTKPPPQQPGPAKPSP-----QQPGSTKPPSQQPGSAKPSAQQP 544
+ + S P PA+ Q ++ P P A P A Q
Sbjct: 540 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599
Query: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT-ICP-LCNTT------- 595
KP S + S + P +A+ P+ +P+T CP NTT
Sbjct: 600 KAEKP-MDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAP 658
Query: 596 -ELLLHVPEKANFNTCTECQTTVCSLCGFNPNP----------HLTEVKEWLCLNCQMKR 644
+ P KA T T + ++ G P E K L + +
Sbjct: 659 VRVGTQAPRKA--GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 716
Query: 645 ALGGDL----APVP--------SSPQPKLKTAPVTTTSAVSK----SSPQPQQTSPKKDA 688
++G L A VP ++P KT P T K S + + S + A
Sbjct: 717 SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
Query: 689 APKQDLS--KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQD 745
+P Q + K + K P + P+ G+ SA K A + +P K +P V + Q+
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
Query: 746 KAPVADDKPKQPKMVKPTTDLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLKTDSAKPS 803
+A P + K + +++ A T P D SS+ +S +EE+ KPS
Sbjct: 837 STVLARGPASVPSVGKA---VATAAQAQTGPEEDSGSSEEESDSEEEAE---TLAQVKPS 890
Query: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK---KAQT 860
++P +K PR + GPS+ G KQ D EE +A
Sbjct: 891 GKTHQIRAALAP--AKESPRKGAAPTPPGKTGPSAAQAG-KQDDSGSSSEESDSDGEAPA 947
Query: 861 KMSPKPDAKPM-----PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA 915
++ KP P SP P P Q TP+++ + +R S
Sbjct: 948 AVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVI 1007
Query: 916 PKSQPTTP------------QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963
P +Q TP + K GAS ++S + Q GP +Q P
Sbjct: 1008 PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNP 1067
Query: 964 ------------MKQAPAPSQPPTSQGPPKS-----TGQAPPAPAKSIPVKKETKAPAAE 1006
+ Q + +QPP ++ P S G P +S V+ + +
Sbjct: 1068 ASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRK 1127
Query: 1007 KLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAE----PQKAVLPTKLEKSPKPESTCPLC 1062
P+ +QA K E+ DS S + E PQ A L P P T L
Sbjct: 1128 PKLPEVQQA--TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL--GPTPSRTETLV 1183
Query: 1063 KTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDI 1122
+ S+D + +L TP LT N Q +A
Sbjct: 1184 EETAAESSED--------DVVAPSQSLLSGYMTPGLTP------ANSQASKATP------ 1223
Query: 1123 RKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKE---- 1178
K+ +PS +S + + ++ A P Q + + K A +K ++
Sbjct: 1224 -KLDSSPS--VSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG 1280
Query: 1179 -------TLSMEKIPPMVTTDQ--KQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRS 1229
TL+++ Q E++++ L E L +E+K + + K S
Sbjct: 1281 AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTEL--LEQERKKVVDTTKESS 1338
Query: 1230 ----EEKKPLLEEKKP---TPEDKK-------------LLPEAKTSAPEEQKHDLLKSQV 1269
E +K L +P TP KK + PE KTS + K K+
Sbjct: 1339 RKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPE-KTSTTSKGKAKRDKASG 1397
Query: 1270 QIAEEKLEGRVAPKTVQ-EGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAK 1328
+ E+K +G + + + E ++ K G G QS PK + K+ K + K
Sbjct: 1398 DVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRK-------K 1450
Query: 1329 PDQVEPGKEKTEKEDDKSDTSSSQQPK 1355
+ + K+K +K K S SQ+ K
Sbjct: 1451 DKEKKEKKKKAKKASTKDSESPSQKKK 1477
Score = 95.9 bits (237), Expect = 9e-19
Identities = 249/1181 (21%), Positives = 408/1181 (34%), Gaps = 188/1181 (15%)
Query: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705
LG DL PSS + K K A S P P + + K+ EP
Sbjct: 113 LGADL---PSSMKEKAK-AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTT 168
Query: 706 LVKQPTLHGS-PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764
LV + GS P+ A P S + A S D+ V + KP VKP
Sbjct: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQ-ADSSSEDTSSSSDETDV-EGKPS----VKPAQ 222
Query: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQ---SFPPTGEKVSPFDSKAI 821
V +SS +TK +S A + P K P + PP P +
Sbjct: 223 --VKASSVSTK--------ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESES 272
Query: 822 PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881
S+S+ + G S+ K +++ V+ P K P +P PPG
Sbjct: 273 SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGT----------PGKGATPAPPGK 322
Query: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
AG V + ++ KP+E S S + + Q +GK GA+ +
Sbjct: 323 ---AG-AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAAS-AP 377
Query: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP-----------KSTGQAPPAP 990
A P P ++GP QA + S K +G+AP
Sbjct: 378 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 437
Query: 991 AKSIPVKKETKAPAA----EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLP 1046
A S P K+ + AA K P A Q K+ E + DS A
Sbjct: 438 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 497
Query: 1047 TKLEKSP--KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
L KSP KP ST + G P T P+ + + +E
Sbjct: 498 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT-------------PSAQVGKWEE- 543
Query: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
++ + G++ AP+ K+ + + +S PPQ K V
Sbjct: 544 -DSESSSEESSDSSDGEV-PTAVAPAQEKSLGNILQAKPTSSPAKGPPQ----KAGPVAV 597
Query: 1165 KTEAEKVI-----LEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219
+ +AEK + E+ ++ E+ P +T Q + K+ + KA +K K
Sbjct: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP--KKTNTTASAK 655
Query: 1220 LIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGR 1279
+ P +R + P +P T P E D S+ +EE+ G
Sbjct: 656 VAP----VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAE---DSSSSEESDSEEEKTGL 708
Query: 1280 VAP--KTVQEGKQPQTKMEGLP------SGTPQSLPKEDDKTTKTIKEQPQPP------- 1324
+ GK Q K +P GT LP + T +K + Q
Sbjct: 709 AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 768
Query: 1325 -----CTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTG--------------- 1364
A P QV+ +KT+ K++ ++++ P + +S G
Sbjct: 769 SDSEEAAASPAQVKTSVKKTQA---KANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS 825
Query: 1365 -----YSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSI 1419
+ S+ L P+ +P+ K + + + +E S SS + S
Sbjct: 826 KVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE---------SD 876
Query: 1420 LEAQASTLADEKSEKKTQPHEVSPE-QPKDQEKTQSLSETLEITISEEEIKESQEERKDT 1478
E +A TLA K KT H++ P + + + T + +++ +
Sbjct: 877 SEEEAETLAQVKPSGKT--HQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGS 934
Query: 1479 FKKDSQQD------IPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRT- 1531
++S D + S++ K FVD R P ++++ + P++ R +
Sbjct: 935 SSEESDSDGEAPAAVTSAQVIKPPLIFVDP---NRSPAGPAATPAQAQAASTPRKARASE 991
Query: 1532 SVGSSSSDEYKQEDSQGSGE-EEDFIRKQIIEM----------SADEDASGSEDDEFIRN 1580
S SSS E + ED + + IR ++ M ++ AS S++ I +
Sbjct: 992 STARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISD 1051
Query: 1581 QLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDES 1640
K+ +T+ KK +T + L +K+S + A + S D A
Sbjct: 1052 GKKQEGPATQVSKKNPASLP--LTQAALKVLAQKASEAQPPVARTQPS--SGVDSAVGTL 1107
Query: 1641 PELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELE 1700
P S +S + G LR+ K E+ S++ S+ +
Sbjct: 1108 P------ATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS----------- 1150
Query: 1701 MESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDS 1741
+S + S ED +G+ S H TP + T V +S
Sbjct: 1151 -DSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAES 1190
Score = 77.8 bits (190), Expect = 3e-13
Identities = 216/980 (22%), Positives = 335/980 (34%), Gaps = 178/980 (18%)
Query: 35 TAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPK 94
TA+ E L + Q S A+G P+ + P A + ++ +D+S +
Sbjct: 562 TAVAPAQEKSLGNIL-----QAKPTSSPAKGPPQKAGPVAV----QVKAEKPMDNSESSE 612
Query: 95 QSGRPPDPGR-PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMM 153
+S D PA ++++ + P ++ +T S K + R + K+
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA 672
Query: 154 PGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGI------- 206
S + AV+ + P + S SE S E K V Q K G
Sbjct: 673 T---SPAGSSPAVAGGTQR--PAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAA 727
Query: 207 ---IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ 263
+K L Q +P + GP + Q K S+ E+ P Q T
Sbjct: 728 SVPVKGSLGQGTAPVLPGKTGP---TVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784
Query: 264 TPQTDHAKLPLQRDASRPQTKQADIVRGESV------KPSLPSPSKPPIQQPTPG----K 313
+T P A P K G+ V K PS KPP++ P +
Sbjct: 785 VKKTQAKANPAA--ARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842
Query: 314 PPAQQPGHEKS-------QPGPAKPPA------------------QPSGLTK-------P 341
PA P K+ Q GP + +PSG T P
Sbjct: 843 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902
Query: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALA-----QPPG 396
+ P P PPG T P A G K + SE+ S+ P A+ +PP
Sbjct: 903 AKESPRKGAAPT-PPGKTGPSAAQAG--KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 959
Query: 397 VGKTPAQQP-GPAKPPTQQ--VGTP-KPLAQQPGLQSPAK--------------APGPTK 438
+ P + P GPA P Q TP K A + +S + PG
Sbjct: 960 IFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRT 1019
Query: 439 TPVQQP-GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
V P +I + + G +S++++ + GPA ++ PA P Q +
Sbjct: 1020 NVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKK-NPASLPLTQ-AAL 1077
Query: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS--AKPSAQQPSPAKPSAQQST 555
K +Q+ +PP + P+ G+ S Q S AK + + P P QQ+T
Sbjct: 1078 KVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQAT 1137
Query: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK--TICPLCNTTELLLHVPEKANFNTCTEC 613
K + + + QG T+ P + TE L V E A ++ +
Sbjct: 1138 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETL--VEETAAESSEDDV 1195
Query: 614 QTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVS 673
SL P LT N Q +A PKL ++P +++ +
Sbjct: 1196 VAPSQSLLSGYMTPGLTPA------NSQASKAT------------PKLDSSPSVSSTLAA 1237
Query: 674 KSSPQPQQTSPKKDAA----PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS- 728
K P +Q + + AA PK +A P K G+P A +
Sbjct: 1238 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ 1297
Query: 729 --LSKPAPPKEPSVPS----------EQDKAPVAD-------------------DKP--K 755
L +P P E V + EQ++ V D D+P +
Sbjct: 1298 CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR 1357
Query: 756 QPKMVKPTT-DLVSSSSATTKPDIPSSKVQSQAE-EKTTPPLKTDSAKPSQSFPPTGEKV 813
P+ K A+ P+ S+ + +A+ +K + +K K S G K
Sbjct: 1358 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG--SQGAKD 1415
Query: 814 SPFDSKAIPRPASDSKIISHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAK 869
P + + S+P E K +K + +KK++ KKA TK S P K
Sbjct: 1416 EPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQK 1475
Query: 870 PMPKGSPTPPGPRPTAGQTV 889
K + TA QTV
Sbjct: 1476 KKKK-------KKKTAEQTV 1488
Score = 60.8 bits (146), Expect = 3e-08
Identities = 136/686 (19%), Positives = 236/686 (34%), Gaps = 100/686 (14%)
Query: 1145 SQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDK 1204
++KT V + + E+E + EAE + + + + + K E++K E +K
Sbjct: 73 AKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMK-EKAKAETEK 131
Query: 1205 ASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDL 1264
A P P K + LL K P K P A T+ E + +
Sbjct: 132 AGKTGNSMPHPATGKTVAN-----------LLSGKSPR---KSAEPSANTTLVSETEEE- 176
Query: 1265 LKSQVQIAEEKLEGRVAPKTVQEGKQP------QTKMEGLPSGTPQSLPKEDDKTTKTIK 1318
S G V+ + +T +EG PS P + K +TK
Sbjct: 177 -GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQV-KASSVSTKESP 234
Query: 1319 EQPQPPCTAKPDQVEPG-----------KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSS 1367
+ P K V P +K E+E + S+ S + ++P G +S
Sbjct: 235 ARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKAS 294
Query: 1368 DGI----------SSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES--- 1414
+ I + G+ + P + + K +E S SS + + E
Sbjct: 295 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 354
Query: 1415 TVLSILEAQASTLADEKSEKKTQPHEVSPEQ---PKDQEKTQSLSETLEITISEEEIKES 1471
++L+A+AS + P + SP + P KT + EE+ + S
Sbjct: 355 AAKALLQAKASGKTSQVGAASA-PAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSS 413
Query: 1472 QEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRT 1531
EE DS+++ P+ K+ V R +ES +P P RK
Sbjct: 414 SEE------SDSEEEAPAQAKPSGKAPQV------RAASAPAKESPRKGAAPAPPRKTGP 461
Query: 1532 SVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTES 1591
+ + ++EDS+ S EE D R+ + M+A Q+K + S +
Sbjct: 462 AAAQVQVGK-QEEDSRSSSEESDSDREALAAMNA--------------AQVKPLGKSPQ- 505
Query: 1592 QKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQ 1651
K T G G + GK + + W ++ + + +ES + E +
Sbjct: 506 VKPASTMGMGPL--GKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTA 563
Query: 1652 ESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDR 1711
+ + G L+ T K + Q K E+P ES +S +
Sbjct: 564 VAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKA-----EKPMDNSESSEESSDSA 618
Query: 1712 SRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPT-- 1769
E +++ A+ P + + ++++ S K + +A + P
Sbjct: 619 DSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGS 678
Query: 1770 -----------IEDSSEEEELREEEE 1784
EDSS EE EEE
Sbjct: 679 SPAVAGGTQRPAEDSSSSEESDSEEE 704
Score = 52.4 bits (124), Expect = 1e-05
Identities = 190/988 (19%), Positives = 330/988 (33%), Gaps = 152/988 (15%)
Query: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA-------PAAEKLEPKAEQAPTVKRTET 1023
S P ++ + +A AK+ P T + P++ K + KAE K +
Sbjct: 79 SDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
Query: 1024 EKKPPPIKDSKSLTA--EPQKAVLP---TKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078
P K +L + P+K+ P T L + E + P G ++
Sbjct: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198
Query: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP 1138
+E + + P + Q ++S + RK PAP
Sbjct: 199 SSEDTSSSSDETDVEGKPSVKPAQV-------KASSVSTKESPARKAAPAPG-------K 244
Query: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV------KETLSMEKI------- 1185
V + K P K KK E+E ++ E E+ + + EKI
Sbjct: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS 304
Query: 1186 -PPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP----LLEEK- 1239
P T + + K A A Q K PEE EE SEE+ P LL+ K
Sbjct: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
Query: 1240 ----------------------KPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE 1277
P P K AK A + ++ S+ +EE+
Sbjct: 365 SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424
Query: 1278 GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKP--DQVEPG 1335
+ P GK PQ + P+ K + P PP P QV+ G
Sbjct: 425 AQAKP----SGKAPQVRAASAPA-----------KESPRKGAAPAPPRKTGPAAAQVQVG 469
Query: 1336 KEKTEKEDDKSDTSSSQQP-------------KSPQGLSDTGYSSDGISSSLGEIP--SL 1380
K++ + ++ S ++ KSPQ + + G +P +
Sbjct: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
Query: 1381 IPTDEKDILKGLKKD--SFSQESSPSSPSDLAKL-----ESTVLSILEAQASTLADEKSE 1433
P + ++D S S+ESS SS ++ E ++ +IL+A+ ++ +
Sbjct: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
Query: 1434 KKTQPHEVSPEQPKDQEKTQSLSETLEITISEE-EIKESQEERKDTFKKDSQQDIPSSKD 1492
+K P V + K + ++S E+ + SEE + + K K + P +
Sbjct: 590 QKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
Query: 1493 HKEKSEFVDDITTRREPYDSVEESSESENSP-VPQRKRRTSVGSSSSDEYKQEDSQGSGE 1551
++ + P + +S + +SP V +R + SSSS+E S
Sbjct: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE--------SDS 701
Query: 1552 EEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL 1611
EE+ + A G ++ +++ K +G + GK
Sbjct: 702 EEEKTGLAVTVGQAKSVGKG-----------LQVKAASVPVKGSLGQGTAPVLPGKTGPT 750
Query: 1612 TRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIE 1671
+ ED+ S + D E SP K +++ R + +
Sbjct: 751 VTQVKAEKQEDS--ESSEEESDSEEAAASPAQVKTSVKKTQAK-----ANPAAARAPSAK 803
Query: 1672 LNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSP 1731
+ K ++Q K P + + G +S+ + T+
Sbjct: 804 GTISAPGKVVTAAAQAK-----QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
Query: 1732 TSVSSLDEDSDSSPSHKKGESKQQRKARHRPHG-------PLLPTIEDSSEEEELREEEE 1784
+ + +EDS SS E + + A+ +P G L P E S +
Sbjct: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE--SPRKGAAPTPP 916
Query: 1785 LLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP----PSNLSPIEDASPTE 1840
+ +Q SSS++S D + A + K P N SP A+
Sbjct: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
Query: 1841 ELRQAAEMEELHRSSCSEYSPSIESDPE 1868
+ + A+ + S + S S ES+ E
Sbjct: 977 QAQAASTPRKARASESTARSSSSESEDE 1004
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 134 bits (337), Expect = 2e-30
Identities = 178/786 (22%), Positives = 302/786 (38%), Gaps = 113/786 (14%)
Query: 116 TDTFRSEQK--------LPGRSPSTISLKESKS-----RTDLKEEHKSSMMPGFLSEVNA 162
TD RS Q+ L R+ +LK +K R++L++ H++ + + +
Sbjct: 308 TDAMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQADIA-SYQEAIQQ 366
Query: 163 LSA--------VSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQ 214
L A +++ + ++ DL++ A E +K+++ E+ + I P+
Sbjct: 367 LDAELRNTKWEMAAQLREYQ--DLLNVKMALDIEIAAYRKLLEGEECR---IGFGPIPFS 421
Query: 215 PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQ-TDHAKLP 273
P+ +PK + T + S++ K+ + ++ T+ Q T+
Sbjct: 422 LPEGLPK--------IPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEE 473
Query: 274 LQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQ-PGPAKPP 332
+++A + K+ + E + PP ++ + A+ P E+++ P AK P
Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP 533
Query: 333 AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP--LGPAKPPAQQTGSEK---PSSEQPG 387
+ + + P K P + + P A+ AK PA+ EK P+ E+
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 388 PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG-LQSPAKAPGPTKTPVQQPGP 446
A A+ P K+P ++ AK P + K A+ P ++SP KA PTK + P
Sbjct: 594 SPAEAKSPEKAKSPVKEE--AKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK 651
Query: 447 GKIPAQQAG--PGKTS----AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500
K P ++ P K A+ P K S + AK P + P K + P AK P
Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711
Query: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
++ K P + P K + P K P K A+ P AK + T V
Sbjct: 712 VKE--EAKSPEKAKSPVKEEAKTPEKAKSP------VKEEAKSPEKAKSPEKAKTLDVKS 763
Query: 561 TGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620
+ P + SP+ K P P + + PEKA + + +
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSP---------VKEEVKSPEKAKSPLKEDAKAPEKEI 814
Query: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQP---KLKTAPVTTTSAVSKSSP 677
P EVK +PV +P K+K P + ++P
Sbjct: 815 ------PKKEEVK-----------------SPVKEEEKPQEVKVKEPPKKAEEEKAPATP 851
Query: 678 QPQQTSP-KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK 736
+ ++ KK+ APK++ K +K P V++P +AK+ D P P K
Sbjct: 852 KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK---ESKVEAKKEEAEDKKKVPTPEK 908
Query: 737 EPSVPSEQDKAPVADDKPKQP-KMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
E E + D KPK+ ++ K D + +P P+ K ++ E+K T
Sbjct: 909 EAPAKVEVKE----DAKPKEKTEVAKKEPD----DAKAKEPSKPAEKKEAAPEKKDT--- 957
Query: 796 KTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP 855
K + AK + P T K D P SK + S S QK P +K E
Sbjct: 958 KEEKAKKPEEKPKTEAKAKEDDKTLSKEP---SKPKAEKAEKSSSTDQKDSKPPEKATED 1014
Query: 856 KKAQTK 861
K A+ K
Sbjct: 1015 KAAKGK 1020
Score = 123 bits (309), Expect = 4e-27
Identities = 135/548 (24%), Positives = 216/548 (39%), Gaps = 56/548 (10%)
Query: 371 PPAQQTGSEKPSSEQPGPKALAQPPGVGKTP----AQQPGPAKPPTQQVGTPKPLAQQPG 426
PPA++ S + ++ P K A+ P K+P A+ P K P + K A+
Sbjct: 504 PPAEEAASPEKEAKSP-VKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK--- 559
Query: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP 486
SP +A P K + P K P + P K A+ K P + P K + P
Sbjct: 560 --SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617
Query: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546
AK P K ++ P K P + P K + P K P ++ + A+ P
Sbjct: 618 AKSP------VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVK 671
Query: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606
A+ + + K P++ SP + P + K+ + + PEKA
Sbjct: 672 AEAKSPEKAK--------SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723
Query: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666
E +T + +P E K K +P +P + +P
Sbjct: 724 SPVKEEAKTPEKA-----KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA 778
Query: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE---PKKPPPLVKQPTLHGS--PSAKAK 721
+KS + + SP+K +P ++ +KAPE PKK VK P K K
Sbjct: 779 DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEE--VKSPVKEEEKPQEVKVK 836
Query: 722 QPP-EADSLSKPAPPK-EPSVPSEQDKAPVAD-DKPKQPKMVKPTTDLVSSSSATTKPDI 778
+PP +A+ PA PK E S++++AP + KPK + +P + S K +
Sbjct: 837 EPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE 896
Query: 779 PSSKVQSQAEEKTTP---PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835
K + EK P +K D AKP + K P D+KA K S P
Sbjct: 897 AEDKKKVPTPEKEAPAKVEVKED-AKPKEKTEVA--KKEPDDAKA--------KEPSKPA 945
Query: 836 PSSESKGQKQVDPVQKKEEP-KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQ 894
E+ +K+ +K ++P +K +T+ K D K + K P + A ++ T Q+
Sbjct: 946 EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK--AEKSSSTDQK 1003
Query: 895 SPKPQEQS 902
KP E++
Sbjct: 1004 DSKPPEKA 1011
Score = 121 bits (303), Expect = 2e-26
Identities = 124/536 (23%), Positives = 207/536 (38%), Gaps = 73/536 (13%)
Query: 410 PPTQQVGTPKPLAQQP---GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT-- 464
PP ++ +P+ A+ P +SPA+A P K + P K P + P K A+
Sbjct: 504 PPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPE 563
Query: 465 --GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG----STKPPPQQPGPAK 518
P K ++ P K P + PAK + P AK P + K P + P K
Sbjct: 564 AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVK 623
Query: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ 578
+ P K P + K A+ P AK ++ K + S P++ SP +
Sbjct: 624 EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS--PVKAEAKSPEKAK 681
Query: 579 PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCL 638
P + K+ PEKA E + +P + VKE
Sbjct: 682 SPVKAEAKS--------------PEKAKSPVKEEAK---------SPEKAKSPVKE---- 714
Query: 639 NCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS--- 695
A + A P + K T +KS + + SP+K +P++ +
Sbjct: 715 -----EAKSPEKAKSPVKEEAK--------TPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761
Query: 696 KAPEPKKP------PPLVKQPTLHGSP-SAKAKQPPEADS-LSKPAPPKEPSVPSEQD-K 746
K+PE K P P K P SP + K P +A S L + A E +P +++ K
Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821
Query: 747 APV-ADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQS 805
+PV ++KP++ K+ +P + P P ++ + ++++ P + K +
Sbjct: 822 SPVKEEEKPQEVKVKEPP----KKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK 877
Query: 806 FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD--PVQKKEEPKKAQTKMS 863
P EK +A A D K + P + +K + + D P +K E KK
Sbjct: 878 KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAK 937
Query: 864 PKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQ 919
K +KP K P + T + P++ PK + +++ L PK++
Sbjct: 938 AKEPSKPAEK-KEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAE 992
Score = 116 bits (290), Expect = 7e-25
Identities = 129/550 (23%), Positives = 220/550 (40%), Gaps = 62/550 (11%)
Query: 976 SQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAE-QAPTVKRTETEKKPPPIKDSK 1034
++ PP +P AKS PVK+E K+PA K K E ++P ++ + K P +++K
Sbjct: 501 TKSPPAEEAASPEKEAKS-PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 559
Query: 1035 SLTAEPQKAVLPTKLE-KSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFN 1093
S P +A P K E KSP + K+ +K P + + K+ V
Sbjct: 560 S----PPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE----- 610
Query: 1094 PTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQ 1153
++ + + K P P+ + P E+ S + A P+
Sbjct: 611 --------------EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE 656
Query: 1154 ---VKLVKKQEQEVKTEAEKVILEKVKETLSME-KIPPMVTTDQKQEESKLEKDKASALQ 1209
K +K + VK EA+ EK K + E K P + K+E EK K+ +
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSP--EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 1210 EKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKP-----TPEDKKLL----PEAKTSAPEEQ 1260
E K + K + EE K + K P+ EE K +PE K L PEAKT A EE
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774
Query: 1261 KHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQ 1320
+ S EK + V + K E + + KE+ K+ +E+
Sbjct: 775 R-----SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 829
Query: 1321 PQ------PPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQ-------GLSDTGYSS 1367
PQ PP A+ ++ + EK+D K + + ++ P+ + S
Sbjct: 830 PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESK 889
Query: 1368 DGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTL 1427
E +PT EK+ K +++ P +++AK E E
Sbjct: 890 VEAKKEEAEDKKKVPTPEKE---APAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAE 946
Query: 1428 ADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDI 1487
E + +K E ++P+++ KT++ ++ + T+S+E K E+ + + D +
Sbjct: 947 KKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSK 1006
Query: 1488 PSSKDHKEKS 1497
P K ++K+
Sbjct: 1007 PPEKATEDKA 1016
Score = 112 bits (279), Expect = 1e-23
Identities = 147/639 (23%), Positives = 252/639 (39%), Gaps = 91/639 (14%)
Query: 735 PKEPSVPSE-----QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789
PK PSV + ++K V + K+ +V+ T+ + T+ + +K + EE
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486
Query: 790 KTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV 849
+ + + + PP E SP K P + E+K +
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASP--EKEAKSPVKE-----------EAKSPAEAKSP 533
Query: 850 QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL 909
+K+E A+ K SP+ P + + +PP + + +P + P++
Sbjct: 534 EKEEAKSPAEVK-SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 592
Query: 910 GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA 969
S +A P + V + A ++A + + + +S A
Sbjct: 593 KSPAEA--KSPEKAKSPVKEE-----AKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEE 645
Query: 970 PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP-------AAEKLEPKAEQAPTVKRTE 1022
P ++ P K ++ P AKS PVK E K+P AE P+ ++P + +
Sbjct: 646 AKSPEKAKSPEKEEAKS-PEKAKS-PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703
Query: 1023 T-EKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTE 1081
+ EK P+K+ P+KA P K E++ PE K+ + +K P + +
Sbjct: 704 SPEKAKSPVKEE---AKSPEKAKSPVK-EEAKTPEK----AKSPVKEEAKSPEKAKSPEK 755
Query: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPT 1141
K L+ ++ A + + R PA P+ + PV
Sbjct: 756 AKT----------------------LDVKSPEAKTPAKEEARS--PADKFPEKAKSPVKE 791
Query: 1142 ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE 1201
E S + A P + K E+E+ + E+VK + E+ P V K+ K E
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEKEIPKK------EEVKSPVKEEEKPQEVKV--KEPPKKAE 843
Query: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQK 1261
++KA A P EEKK +EE + E KP +EEKK +K E+K A +E+
Sbjct: 844 EEKAPA----TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP--KESKVEAKKEEA 897
Query: 1262 HDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQP 1321
D K +V E++ +V V+E +P+ K E + KE K + + P
Sbjct: 898 ED--KKKVPTPEKEAPAKV---EVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAP 952
Query: 1322 QPPCT----AKPDQVEPGKEKTEKEDDKSDTSSSQQPKS 1356
+ T AK + +P E KEDDK+ + +PK+
Sbjct: 953 EKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA 991
Score = 102 bits (255), Expect = 8e-21
Identities = 122/566 (21%), Positives = 218/566 (38%), Gaps = 66/566 (11%)
Query: 489 PPPQQPGSAKPPSQQP--GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546
PP ++ S + ++ P K P + P K + P K P + AK A+ P
Sbjct: 504 PPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPE 563
Query: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606
AK ++ K ++ S + + SP+ ++ S K+ PEKA
Sbjct: 564 AKSPEKEEAKSPAEVKSPEKAK----SPAKEEAKSPAEAKS--------------PEKAK 605
Query: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666
E ++ P + VKE + K A V S + K T
Sbjct: 606 SPVKEEAKS---------PAEAKSPVKE------EAKSP-----AEVKSPEKAKSPTKEE 645
Query: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV--KQPTLHGSP-SAKAKQP 723
+ +KS + + SP+K +P + +K+PE K P K P SP +AK P
Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP 705
Query: 724 PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783
+A S P KE + E+ K+PV ++ K P + S P+ +
Sbjct: 706 EKAKS-----PVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD 760
Query: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ 843
E KT P K ++ P+ FP + + K+ + S K + K +
Sbjct: 761 VKSPEAKT--PAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKE 818
Query: 844 KQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQ---- 899
+ PV+++E+P++ + K PK + +P + + + P +++PKP+
Sbjct: 819 EVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK-KEAPKPKVEEK 877
Query: 900 -----EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGP 954
E+ + + K + TP++ K+ + + + + +P
Sbjct: 878 KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKK--EPDD 935
Query: 955 HSQSGPGAPM-KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAE 1013
P P K+ AP + T + K + P AK+ K++ K + E +PKAE
Sbjct: 936 AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKA---KEDDKTLSKEPSKPKAE 992
Query: 1014 QAPTVKRTETEKKPPPIKDSKSLTAE 1039
+A T+ + PP K ++ A+
Sbjct: 993 KAEKSSSTDQKDSKPPEKATEDKAAK 1018
Score = 98.6 bits (244), Expect = 1e-19
Identities = 132/593 (22%), Positives = 235/593 (39%), Gaps = 39/593 (6%)
Query: 1127 PAP-SGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKI 1185
P P S P+ P +P+ S+ K ++K+V+K E+E E+ +V E ++ E+
Sbjct: 417 PIPFSLPEGLPK-IPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEE 475
Query: 1186 PPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEE---KIRSEEKKPLLEEKKPT 1242
+ K+EE E++ +E K P E+ PE+E ++ E K P E K P
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSP-AEAKSPE 534
Query: 1243 PEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQ-TKMEGLPSG 1301
E+ K E K +PE+ K + E K + K+ E K P+ K
Sbjct: 535 KEEAKSPAEVK--SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 592
Query: 1302 TPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTE-KEDDKSDTSSSQQPKSPQGL 1360
+ K +K +KE+ + P AK E K E K +K+ + + ++ KSP+
Sbjct: 593 KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE-K 651
Query: 1361 SDTGYSSDGISSSLGEIPSLIPTDEKDILKG-LKKDSFSQESSPSSPSDLAKLESTVLSI 1419
+ + + S + P + K +K ++ S E + S + AK S
Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711
Query: 1420 LEAQASTLADEKS----EKKTQPHEVSP--EQPKDQEKTQS--LSETLEITISEEEIKES 1471
++ +A + KS E KT SP E+ K EK +S ++TL++ E +
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAK 771
Query: 1472 QEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRT 1531
+E R K + P ++ K + + + + E SPV + ++
Sbjct: 772 EEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ 831
Query: 1532 SVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTES 1591
V + +E+ + + + + E + ++A + +E +++ S
Sbjct: 832 EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 891
Query: 1592 QKKEETKGKGKITA--------------GKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAF 1637
KKEE + K K+ K + T + D+ + S E EA
Sbjct: 892 AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAA 951
Query: 1638 DESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTS 1690
E + K E K+++ EE T KT+ S K AE ++K +S
Sbjct: 952 PEKKDTK--EEKAKKPEEKPKTEAKAKEDDKTL---SKEPSKPKAEKAEKSSS 999
Score = 93.6 bits (231), Expect = 5e-18
Identities = 125/572 (21%), Positives = 215/572 (37%), Gaps = 96/572 (16%)
Query: 671 AVSKSSPQPQQTSPKKDAAPKQDLSKAPEPK--KPPPLVKQPTLHGSPSAK-AKQPPEAD 727
A +SP+ + SP K+ A +K+PE + K P VK P SP+ + AK PPEA
Sbjct: 506 AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565
Query: 728 SLSKP---------APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP-- 776
S K +P K S E+ K+P P++ K P + S + P
Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK--SPVKEEAKSPAEAKSPVK 623
Query: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV-SPFDSKA-IPRPASDSKIISHP 834
+ S + ++ EK P K ++ P ++ P E+ SP +K+ + A + P
Sbjct: 624 EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSP 683
Query: 835 GPSSESKGQKQVDPVQKK-EEPKKAQTKM-----SPKPDAKPMPKGSPTPPGPRPTAGQT 888
+ +K PV+++ + P+KA++ + SP+ P+ + + TP + +
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEE 743
Query: 889 VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST 948
+P+++ P E+++ + K + +P + K S +
Sbjct: 744 AKSPEKAKSP-EKAKTLDVKSPEAKTPAKEEARSPADKFPEK----AKSPVKEEVKSPEK 798
Query: 949 AGQPGPHSQSGPG----------APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVK- 997
A P P +P+K+ P + + P K+ + PA K+ K
Sbjct: 799 AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKD 858
Query: 998 -KETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056
K+ +AP E +PK E EKK P ++ K E +K K +K P PE
Sbjct: 859 SKKEEAPKKEAPKPKVE----------EKKEPAVEKPKESKVEAKKEEAEDK-KKVPTPE 907
Query: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116
P K E+ +K TE+ +
Sbjct: 908 KEAP-AKVEVKEDAKPKEK-----------------------TEVAK------------- 930
Query: 1117 GQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV 1176
+ D + P+ K P ++ +K P + K + E K + + L K
Sbjct: 931 KEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEE-----KPKTEAKAKEDDKTLSKE 985
Query: 1177 KETLSMEKIPPMVTTDQKQEE--SKLEKDKAS 1206
EK +TDQK + K +DKA+
Sbjct: 986 PSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017
Score = 93.6 bits (231), Expect = 5e-18
Identities = 119/511 (23%), Positives = 198/511 (38%), Gaps = 55/511 (10%)
Query: 1124 KMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSME 1183
K P P+ + P E+ S PP+ K +K+E K+ AE EK K E
Sbjct: 539 KSPAEVKSPEKAKSPAKEEAKS-----PPEAKSPEKEE--AKSPAEVKSPEKAKSPAKEE 591
Query: 1184 KIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTP 1243
P E EK K+ +E K E K + EE K +E K P + K PT
Sbjct: 592 AKSPA-------EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP-EKAKSPTK 643
Query: 1244 EDKKLLPEAKTSAPEEQKH-DLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGT 1302
E+ K +AK+ EE K + KS V+ AE K + E K P+ +
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVK-AEAKSPEKAKSPVKAEAKSPEKAKSPV---- 698
Query: 1303 PQSLPKEDDKTTKTIKEQPQPPCTAK-PDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLS 1361
+ K +K +KE+ + P AK P + E + K K + S ++ KSP+
Sbjct: 699 -KEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAK 757
Query: 1362 DTGYSS--------DGISSSLGEIPSLIPTDEKDILKGLKK-DSFSQESSPSSPSDLAKL 1412
S + S + P + K+ +K +K S +E + + ++ K
Sbjct: 758 TLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK 817
Query: 1413 ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQ 1472
E + E + K K E +P PK +EK S E E E + +
Sbjct: 818 EEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE--EAPKKEAPKPKVE 875
Query: 1473 EERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTS 1532
E+++ +K + + + K+ E + V T +E VE ++ + K +T
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDKKKVP--TPEKEAPAKVEVKEDA------KPKEKTE 927
Query: 1533 VGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQ 1592
V D+ K ++ E++ E A +D + + + E TE++
Sbjct: 928 VAKKEPDDAKAKEPSKPAEKK-------------EAAPEKKDTKEEKAKKPEEKPKTEAK 974
Query: 1593 KKEETKGKGKITAGKHRRLTRKSSTSIDEDA 1623
KE+ K K + KSS++ +D+
Sbjct: 975 AKEDDKTLSKEPSKPKAEKAEKSSSTDQKDS 1005
Score = 75.9 bits (185), Expect = 1e-12
Identities = 111/532 (20%), Positives = 189/532 (35%), Gaps = 79/532 (14%)
Query: 5 ASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQ 64
A E + PE + + SP PA EA ++ + + V A+
Sbjct: 554 AKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK 613
Query: 65 GLPKGSVP-PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQ 123
+ P A+SP+ + E S P K+ + P+ + P ++++ + +S
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKS-PTKEEAKSPEKAK--SPEKEEAKSPEKAKSPV 670
Query: 124 KLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSE 183
K +SP K+++ +K E KS
Sbjct: 671 KAEAKSP-------EKAKSPVKAEAKS--------------------------------- 690
Query: 184 ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243
+K K KE+ K K P++++ P K + P ++ + TP+ S
Sbjct: 691 ------PEKAKSPVKEEAKSPEKAKSPVKEEAKSP-EKAKSPVKEEAK---TPEKAKSPV 740
Query: 244 PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSK 303
E+ KS P P + T ++ AK P + +A P K + + VK + SP K
Sbjct: 741 KEEAKS-PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK-SPVKEEVKSPEK 798
Query: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363
K P ++ ++ P K +P Q VK P + K PA
Sbjct: 799 AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP---------QEVKVKEPPKKAEEEKAPA 849
Query: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
P +T +K S ++ PK A P V + ++P KP +V K A+
Sbjct: 850 TP---------KTEEKKDSKKEEAPKKEAPKPKVEE--KKEPAVEKPKESKVEAKKEEAE 898
Query: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483
+ P K V++ K + A A+ P+KP + + +
Sbjct: 899 DKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTK 958
Query: 484 PGPAKPPPQQPGS-AKPPSQQPGSTKPP--PQQPGPAKPSPQQPGSTKPPSQ 532
AK P ++P + AK +K P P+ K S +KPP +
Sbjct: 959 EEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK 1010
Score = 62.8 bits (151), Expect = 9e-09
Identities = 129/718 (17%), Positives = 267/718 (37%), Gaps = 65/718 (9%)
Query: 1189 VTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKL 1248
V D+ E +K+ D + QE+ + E + K LE ++ ED+
Sbjct: 295 VRLDRLSEAAKVNTDAMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQ 354
Query: 1249 LPEAK-TSAPEEQKHDLLKSQVQIAEEKLEGR-------------VAPKTVQEGKQPQTK 1294
A A ++ +L ++ ++A + E + A + + EG++ +
Sbjct: 355 ADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIG 414
Query: 1295 MEGLPSGTPQSLPKEDDKTTKT-IKEQPQPPCTAKPDQ----VEPGKEKTEKEDDKSDTS 1349
+P P+ LPK +T +K + + K ++ VE E+T+ ++ ++
Sbjct: 415 FGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTE-E 473
Query: 1350 SSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDL 1409
++ K +G + G +E++ G ++ +SP
Sbjct: 474 EEKEAKEEEGKEEEG------------------GEEEEAEGGEEETKSPPAEEAASPEKE 515
Query: 1410 AKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIK 1469
AK S V ++ A + EK E K+ SPE+ K K ++ S + +EE K
Sbjct: 516 AK--SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAK 573
Query: 1470 -----ESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSES----- 1519
+S E+ K K++++ + K KS ++ + E V+E ++S
Sbjct: 574 SPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK 633
Query: 1520 --ENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEF 1577
E + P ++ S + S E ++ S + + E + + ++ E
Sbjct: 634 SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK 693
Query: 1578 IRNQLKEISSSTESQK---KEETKG--KGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDE 1632
++ +KE + S E K KEE K K K + + K+ + + E+A
Sbjct: 694 AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP 753
Query: 1633 DDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLY 1692
+ ++ ++K E K+ EE + K+ + + A+S K+ +
Sbjct: 754 EKA---KTLDVKSPEAKTPAKEEARSPADKFPEKAKS-PVKEEVKSPEKAKSPLKEDAKA 809
Query: 1693 FDEEPELEMESLTDSPEDRSRGE---GSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKK 1749
++E + E + E+ E A +P + D + +P +
Sbjct: 810 PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEA 869
Query: 1750 GESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKK 1809
+ K + K P +E EE E +++ E+E ++E ++ +K++
Sbjct: 870 PKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPT-PEKEAPAKVEVKEDAKPKEKTEV 928
Query: 1810 DKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDP 1867
K E + +E K + E EE + E + + E ++ +P
Sbjct: 929 AKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP 986
Score = 48.9 bits (115), Expect = 1e-04
Identities = 98/480 (20%), Positives = 167/480 (34%), Gaps = 114/480 (23%)
Query: 1503 ITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIE 1562
I + E V E SE E V ++ T V ++E ++E + G+EE E
Sbjct: 436 IKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE--------E 487
Query: 1563 MSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDED 1622
+E+A G E++ T+S EE K ++ + + E+
Sbjct: 488 GGEEEEAEGGEEE-------------TKSPPAEEAASPEK-----------EAKSPVKEE 523
Query: 1623 AGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSA 1682
A +SP E KS E EE + A+ S
Sbjct: 524 A---------------KSPA----EAKSPEKEEA-----------------KSPAEVKSP 547
Query: 1683 ESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSD 1742
E ++ PE + SPE + E S S SP +
Sbjct: 548 EKAKSPAKEEAKSPPEAK------SPE---KEEAKSPAEVKSPEKAKSPAKEEAKSPAEA 598
Query: 1743 SSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKS 1802
SP K K++ K+ P+ + +E + + + KE+ K E + K
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
Query: 1803 SSKKSKKDKDELRAQRR---------RERPKTPPSNLSPIEDASPTEE-----LRQAAEM 1848
+K +K K ++A+ + + K+P SP+++ + + E +++ A+
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718
Query: 1849 EELHRSSCSE--YSPSIESDPEGFEI-SPEKIIEVQKV---------YKLPTAVSLYSPT 1896
E +S E +P P E SPEK +K K P SP
Sbjct: 719 PEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA 778
Query: 1897 D----------EQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAANER-DEVFEKEP 1945
D ++ + E ++ LK + E+ + K + K+ E+ EV KEP
Sbjct: 779 DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEP 838
Score = 41.6 bits (96), Expect = 0.021
Identities = 58/249 (23%), Positives = 94/249 (37%), Gaps = 29/249 (11%)
Query: 3558 KTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPP 3617
K +GG + +T+SP A SP K+ K P E + ++ +
Sbjct: 484 KEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE-----A 538
Query: 3618 KSPKVLYSPISPLSPGKALESAFVPYEKPLPDD---ISPQKVLHPDMAKVP----PASPK 3670
KSP + SP SP K E A P E P+ SP +V P+ AK P SP
Sbjct: 539 KSPAEVKSPEKAKSPAK--EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA 596
Query: 3671 TAKMMQRSMS-------DPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRT 3723
AK +++ S P E +++P + K S T + + +K K
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK-SPTKEEAKSPEKAK-- 653
Query: 3724 LPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRKK 3783
+P EE + ++ ++ A AK ++ V+ E+ K
Sbjct: 654 --SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK---SPEKAKSPVKEEAKSPEKA 708
Query: 3784 QAELDEEEK 3792
++ + EE K
Sbjct: 709 KSPVKEEAK 717
Score = 41.6 bits (96), Expect = 0.021
Identities = 45/216 (20%), Positives = 81/216 (37%), Gaps = 22/216 (10%)
Query: 46 SQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRP 105
S + EEE+ Q V PK + A +P K++ PK+ P
Sbjct: 822 SPVKEEEKPQEVKVKEP----PKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK 877
Query: 106 AQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSA 165
+P + K + + +++ + KE+ ++ ++KE+ K P +EV
Sbjct: 878 KEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAK----PKEKTEVAKKEP 933
Query: 166 VSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIK-----PPLQQQPPKPIP 220
+ + P EA+ E+ K++ +K + KP+ K L ++P KP
Sbjct: 934 DDAKAKE--PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA 991
Query: 221 KQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK 256
++ Q+D P PEK GK
Sbjct: 992 EKAEKSSSTDQKDSKP-------PEKATEDKAAKGK 1020
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 132 bits (331), Expect = 1e-29
Identities = 140/446 (31%), Positives = 168/446 (37%), Gaps = 70/446 (15%)
Query: 162 ALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKP-EGIIKPPLQQQPPKPIP 220
AL A+SS N + + SQEE+ + QG P +G KP Q PP P
Sbjct: 9 ALLALSSAQNL--------NEDVSQEESPSL--IAGNPQGAPPQGGNKP---QGPPSPPG 55
Query: 221 KQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR 280
K QGP P Q P+ P K + PP G QGP P +
Sbjct: 56 KPQGP---PPQGGNQPQG-PPPPPGKPQGPPPQGGNKPQGPPP---------PGKPQGPP 102
Query: 281 PQTKQADIVRGESVKPSLPSP---SKPPIQQPTPGKPPAQQP-GHEKSQ----PG-PAKP 331
PQ ++ R KP P P ++P P PGKP P G K Q PG P P
Sbjct: 103 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 162
Query: 332 PAQPSGLTKPLAQQPGTVKPPV-----QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386
P Q ++ PG + P QP G PP +P GP PP G KP P
Sbjct: 163 PPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQ---GGNKPQGPPP 217
Query: 387 GPKALAQPP-GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG 445
K PP G K+ + + P KP G P QP Q P PG + P P
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQ----GPPPQGGNQP--QGPPPPPGKPQGP--PPQ 269
Query: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPG-PAKPPPQQPGSAKPPSQQP 504
G P PGK P PP Q ++ PG P PPPQ + P P
Sbjct: 270 GGNKPQGPPPPGK-------PQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP 322
Query: 505 GSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP--SPAKPSAQQSTKPVSQT- 561
G + PP Q G P PG + P Q GS SA+ P P P Q+ P
Sbjct: 323 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP 382
Query: 562 -GSGKPLQP---PTVSPSAKQPPSQG 583
G P QP P P P QG
Sbjct: 383 PAGGNPQQPQAPPAGQPQGPPRPPQG 408
Score = 113 bits (282), Expect = 6e-24
Identities = 116/392 (29%), Positives = 141/392 (35%), Gaps = 74/392 (18%)
Query: 201 GKPEGIIKPPLQ----QQPPKPIPKQQGP------GRDPLQQDGTPKSISSQQPEKIKSQ 250
GKP+G PP Q Q P P K QGP R P G P+ Q + +
Sbjct: 76 GKPQG---PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 132
Query: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQT--KQADIVRGESVKPSLPSP---SKPP 305
PP GKP P Q P + P ++ R KP P P ++P
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ 192
Query: 306 IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA-- 363
P PGKP P GP PP +P G P Q + PPG + P
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQG---PPPQGDNKSQSARSPPGKPQGPPPQ 248
Query: 364 ---QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
QP GP PP + G Q G K PP PG + P Q G+
Sbjct: 249 GGNQPQGPPPPPGKPQGPPP----QGGNKPQGPPP---------PGKPQGPPPQGGSKSR 295
Query: 421 LAQQPGLQSPAKAPGPTKTPVQQP-GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP 479
++ P P K GP QP GP P + GP PP P P
Sbjct: 296 SSRSP----PGKPQGPPPQGGNQPQGPPPPPGKPQGP------------PPQGGNKPQGP 339
Query: 480 PPQQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
PP PG P PPPQ ++ PG + PPQQ G P P P QQP A
Sbjct: 340 PP--PGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP--QQP-QAP 394
Query: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
P+ Q P +P G+P +PP
Sbjct: 395 PAGQPQGPPRPPQ-----------GGRPSRPP 415
Score = 112 bits (280), Expect = 9e-24
Identities = 118/352 (33%), Positives = 137/352 (38%), Gaps = 68/352 (19%)
Query: 192 KQKVVQKEQGKPEGIIKPPLQ-----QQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEK 246
K + + GKP+G PP Q Q PP P K QGP P Q P+
Sbjct: 107 KSRSPRSPPGKPQG---PPPQGGNQPQGPPPPPGKPQGP---PPQGGNKPQG-------- 152
Query: 247 IKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKP-- 304
PP GKP QGP PQ D+ + +PQ G + P P KP
Sbjct: 153 ----PPPPGKP-QGPP--PQGDNKSRSSRSPPGKPQGPPPQ--GGNQPQGPPPPPGKPQG 203
Query: 305 --------PIQQPTPGKPPAQQP-GHEKSQPG---PAKPPA-QPSGLTKPLAQQPGTVKP 351
P P PGKP P G KSQ P KP P G +P P KP
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKP 263
Query: 352 PVQPPGTTKPPAQPLGPAKP--PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK 409
PP P P P KP P Q GS+ SS P K PP G P GP
Sbjct: 264 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQP---QGPPP 320
Query: 410 PPTQQVGTPKPLAQQP-GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK 468
PP + G P +P G P K GP P Q G K + ++ PGK P
Sbjct: 321 PPGKPQGPPPQGGNKPQGPPPPGKPQGP---PPQ--GGSKSRSARSPPGK-------PQG 368
Query: 469 PPSQL-PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKP 519
PP Q P PPP PA PQQP + PP+ QP PPQ P++P
Sbjct: 369 PPQQEGNNPQGPPP----PAGGNPQQPQA--PPAGQPQGPPRPPQGGRPSRP 414
Score = 110 bits (274), Expect = 5e-23
Identities = 108/365 (29%), Positives = 137/365 (37%), Gaps = 64/365 (17%)
Query: 279 SRPQTKQADIVRGESVKPSLPSPSKPPIQQPT----PGKPPAQ---QPGHEKSQP-GPAK 330
S Q D+ + ES +P P Q P PP + P +QP GP
Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP 73
Query: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPG------TTKPPAQPLGPAKPPAQQTGSEKPSSE 384
PP +P G +P PP +P G ++ P P G + P Q G++
Sbjct: 74 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 133
Query: 385 QPGPKALAQPPGVGKTPAQQPGPAK-----------------PPTQQVGTPKPLAQQPGL 427
P K PP G P P P K PP + G P QP
Sbjct: 134 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP-- 191
Query: 428 QSPAKAPGPTKTPVQQ--------PGPGKI--PAQQAGPGKTSAQQTGPTKPPSQLP--- 474
Q P PG + P Q P PGK P Q G K+ + ++ P KP P
Sbjct: 192 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ-GDNKSQSARSPPGKPQGPPPQGG 250
Query: 475 -GPAKPPPQQPGPAKPPPQ---QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530
P PPP P PPPQ +P PP + G PPPQ ++ S PG + P
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---PPPQGGSKSRSSRSPPGKPQGP 307
Query: 531 SQQPGSAKPSAQQPSPAKPSA---QQSTKPVSQTGSGKPLQPP----TVSPSAKQPPS-- 581
Q G+ +P P P KP Q KP GKP PP + S SA+ PP
Sbjct: 308 PPQGGN-QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKP 366
Query: 582 QGLPK 586
QG P+
Sbjct: 367 QGPPQ 371
Score = 85.9 bits (211), Expect = 1e-15
Identities = 119/463 (25%), Positives = 153/463 (33%), Gaps = 82/463 (17%)
Query: 442 QQPGPGKIPAQ-QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500
Q+ P I Q P + + GP PP + P PPPQ + PP PG + P
Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPPSPPGK---PQGPPPQGGNQPQGPPPPPGKPQGP 81
Query: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
Q G+ P PG + P Q ++ P PG KP Q P P + Q P
Sbjct: 82 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG--KP--QGPPPQGGNQPQGPPPPP- 136
Query: 561 TGSGKPLQPPTVSPSAKQ-PPSQGLPKTICPLC-NTTELLLHVPEKANFNTCTECQTTVC 618
GKP PP + Q PP G P+ P N + P K
Sbjct: 137 ---GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQ------------ 181
Query: 619 SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSP- 677
P P GG+ P P K + P + P
Sbjct: 182 -----GPPPQ------------------GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 218
Query: 678 -QPQQTSPKKDAAPKQDLSKAPEPKKPPPLV-KQPTLHGSPSAKAKQPPEADSLSKPAPP 735
+PQ P+ D + S +P+ PPP QP P K + PP +KP P
Sbjct: 219 GKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG-NKPQGP 277
Query: 736 KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
P P Q P K + SS S KP P + +Q + PP
Sbjct: 278 PPPGKP--QGPPPQGGSKSR------------SSRSPPGKPQGPPPQGGNQPQGPPPPPG 323
Query: 796 KTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEP 855
K P P G P P P SK S P G+ Q P Q+ P
Sbjct: 324 KPQGPPPQGGNKPQGPP--PPGKPQGPPPQGGSKSRSARSPP----GKPQGPPQQEGNNP 377
Query: 856 KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP 898
+ P P A P+ PP +P Q P P Q +P
Sbjct: 378 Q------GPPPPAGGNPQQPQAPPAGQP---QGPPRPPQGGRP 411
Score = 80.5 bits (197), Expect = 4e-14
Identities = 94/374 (25%), Positives = 121/374 (32%), Gaps = 41/374 (10%)
Query: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP--QQTSPKKDAAPKQDLSKAPEPKKPP 704
GG+ P SP K + P + P P Q P + Q +P+ PP
Sbjct: 43 GGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 102
Query: 705 PLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPS----EQDKAPVADDKPKQPKMV 760
P + SP K + PP PP P P + P P +P+
Sbjct: 103 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 162
Query: 761 KPTTDLVSSSSATT--KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDS 818
P D S SS + KP P + +Q + PP K P P G P
Sbjct: 163 PPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP--PPGK 220
Query: 819 KAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTP 878
P P D+K S P + +G Q + P P P P+G P P
Sbjct: 221 PQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 280
Query: 879 ---PGPRPTAG------QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ----- 924
GP P G ++ P Q P PQ G+ P P PQ
Sbjct: 281 GKPQGPPPQGGSKSRSSRSPPGKPQGPPPQG---------GNQPQGPPPPPGKPQGPPPQ 331
Query: 925 -------ETVTGKLFGFGASIFSQASNLISTAGQP-GPHSQSGPGAPMKQAPAPSQPPTS 976
GK G S++ + S G+P GP Q G PA P
Sbjct: 332 GGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391
Query: 977 QGPPKSTGQAPPAP 990
Q PP Q PP P
Sbjct: 392 QAPPAGQPQGPPRP 405
Score = 74.7 bits (182), Expect = 2e-12
Identities = 97/398 (24%), Positives = 132/398 (33%), Gaps = 49/398 (12%)
Query: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKA 720
L A + +SA + + Q+ SP A Q PP +P SP K
Sbjct: 6 LSVALLALSSAQNLNEDVSQEESPSLIAGNPQGA--------PPQGGNKPQGPPSPPGKP 57
Query: 721 KQPPEADSLSKPAPPKEPSVPS----EQDKAPVADDKPKQPKMVKPTTDLV-SSSSATTK 775
+ PP PP P P + P P +P+ P D S S K
Sbjct: 58 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGK 117
Query: 776 PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835
P P + +Q + PP K P P G P P P D+K S
Sbjct: 118 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP--PPPGKPQGPPPQGDNKSRSSRS 175
Query: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP---TPPGPRP------TAG 886
P + +G Q + P P P P+G P P GP P +
Sbjct: 176 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSA 235
Query: 887 QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ------------ETVTGKLFGF 934
++ P Q P PQ G+ P P PQ GK G
Sbjct: 236 RSPPGKPQGPPPQG---------GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 286
Query: 935 GASIFSQASNLISTAGQP-GPHSQSGPGAPMKQAPAPSQP--PTSQGPPKSTGQAPPAPA 991
S++ + S G+P GP Q G P P P +P P QG K G PP
Sbjct: 287 PPQGGSKSRSSRSPPGKPQGPPPQGG-NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 345
Query: 992 KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
+ P + +K+ +A K + P + + PPP
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPP 383
Score = 51.6 bits (122), Expect = 2e-05
Identities = 56/242 (23%), Positives = 79/242 (32%), Gaps = 40/242 (16%)
Query: 821 IPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG 880
+ + S S I +P + G K P +P+ + +P P P G P G
Sbjct: 23 VSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGK--PQG 80
Query: 881 PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFS 940
P P G P KPQ + G + +P+S P PQ
Sbjct: 81 PPPQGGNKPQGPPPPGKPQGPPPQ-----GDKSRSPRSPPGKPQ---------------- 119
Query: 941 QASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP--PTSQGPPKSTGQAPPAPAKSIPVKK 998
GP Q G P P P +P P QG K G PP + P +
Sbjct: 120 ------------GPPPQGG-NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 166
Query: 999 ETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPEST 1058
+ K+ ++ K + P + + PPP K PQ P KP+
Sbjct: 167 DNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP--PGKPQGPPPQGGNKPQGPPPPGKPQGP 224
Query: 1059 CP 1060
P
Sbjct: 225 PP 226
Score = 46.2 bits (108), Expect = 8e-04
Identities = 49/175 (28%), Positives = 58/175 (33%), Gaps = 17/175 (9%)
Query: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP--------PPPPP 2422
KP P G P +P D S P PP P PPP PPPPP
Sbjct: 77 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136
Query: 2423 PPPPLPPPT-SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT-RICT 2480
P PPP KP P P P D + + + G P
Sbjct: 137 GKPQGPPPQGGNKPQGPPPPGKPQGPP-----PQGDNKSRSSRSPPGKPQGPPPQGGNQP 191
Query: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTG 2535
PPP P KP P ++P+ PP P+ PQ +Q KP G
Sbjct: 192 QGPPPPPGKPQGPPP--QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQG 244
Score = 46.2 bits (108), Expect = 8e-04
Identities = 48/173 (27%), Positives = 59/173 (34%), Gaps = 32/173 (18%)
Query: 2371 KPASQLPSG---SPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPP-----PP 2422
KP P G S S S P KP+ QP PPPPP P PPP P
Sbjct: 220 KPQGPPPQGDNKSQSARSPPGKPQ----GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 275
Query: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482
PPP P P P K + + + P P P
Sbjct: 276 GPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP------------------PPQGGNQPQG 317
Query: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTG 2535
PPP P KP P ++P+ PP P+ PQ + ++ KP G
Sbjct: 318 PPPPPGKPQGPPP--QGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQG 368
Score = 45.1 bits (105), Expect = 0.002
Identities = 45/173 (26%), Positives = 54/173 (31%), Gaps = 23/173 (13%)
Query: 2363 SGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP 2422
+G G P G PS P P P QP PPPPP P PPP
Sbjct: 33 AGNPQGAPPQGGNKPQGPPSPPGKPQGPPP-------QGGNQPQGPPPPPGKPQGPPPQG 85
Query: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482
P PP KP P P D + + P
Sbjct: 86 GNKPQGPPPPGKPQGPP--------------PQGDKSRSPRSPPGKPQGPPPQGGNQPQG 131
Query: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTG 2535
PPP P KP P ++P+ PP P+ PQ ++ KP G
Sbjct: 132 PPPPPGKPQGPPP--QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG 182
Score = 40.4 bits (93), Expect = 0.046
Identities = 46/172 (26%), Positives = 63/172 (36%), Gaps = 10/172 (5%)
Query: 2371 KPASQLPSGS--PSVSSLPAKPR-PFFRSSSLDISAQPPPPPPPPPPPP---PPPPPPPP 2424
KP P G P P KP+ P + + S++ PP P PPP P PPPP
Sbjct: 138 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP 197
Query: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVT-RICTTAP 2483
P P P+ P+ P P D + + + G P P
Sbjct: 198 PGKPQGPPPQGGNKPQGPPPPGKP-QGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP 256
Query: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTG 2535
PP P KP P ++P+ PP P+ PQ + ++ KP G
Sbjct: 257 PPPPGKPQGPPP--QGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQG 306
Score = 35.4 bits (80), Expect = 1.5
Identities = 22/69 (31%), Positives = 28/69 (40%)
Query: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
P Q S S S S P KP+ + + PPP P P PP P P PP
Sbjct: 348 PPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 407
Query: 2432 SPKPTILPK 2440
+P+ P+
Sbjct: 408 GGRPSRPPQ 416
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 125 bits (315), Expect = 8e-28
Identities = 280/1311 (21%), Positives = 461/1311 (35%), Gaps = 234/1311 (17%)
Query: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ--QP 425
P+ PAQ S + E P KA P VG Q G A PP ++ P+ ++ +
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE 275
Query: 426 GLQSPAKAPGPTKTPVQQ-----------------PGPGKIPAQQAGPGKTSAQ-QTGPT 467
G +S +AP T++ V+ PG G PA G ++Q + G
Sbjct: 276 GSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 468 KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527
+ S+ ++ PA Q ++ SQ ++ P + P +P PG T
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGA-APAPPGKT 394
Query: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL--- 584
P + + K S ++ S + P SGK Q S AK+ P +G
Sbjct: 395 GPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 585 -PKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMK 643
P+ P ++ + E+ + ++ E + +L N +VK L + Q+K
Sbjct: 455 PPRKTGPAA--AQVQVGKQEEDSRSSSEESDSDREALAAMNA----AQVKP-LGKSPQVK 507
Query: 644 RALGGDLAPVP--SSPQPKLKTAPVTTTSAVSK----SSPQPQQTSPKKDA------APK 691
A + P+ + P P K P T ++ V K S +++S D AP
Sbjct: 508 PASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA 567
Query: 692 QDLS--------------KAPEPKKPPPLVK----------QPTLHGSPSAKAKQPPEAD 727
Q+ S K P K P V+ + + S SA +++ P A
Sbjct: 568 QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAM 627
Query: 728 SLSKPAP----------PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA----T 773
+ ++ P PK+ + + APV + P+ T SS A T
Sbjct: 628 TAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT-QAPRKAGTATSPAGSSPAVAGGT 686
Query: 774 TKP--DIPSSKVQSQAEEKTTPPLKTDSAKP--------SQSFPPTGE-----------K 812
+P D SS+ EEKT + AK + S P G K
Sbjct: 687 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 746
Query: 813 VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872
P ++ DS+ S E+ P Q K KK Q K +P P
Sbjct: 747 TGPTVTQVKAEKQEDSESSEEESDSEEAAAS----PAQVKTSVKKTQAKANPAAARAPSA 802
Query: 873 KGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT------TPQET 926
KG+ + PG TA Q+SP + R N + P S P+ T +
Sbjct: 803 KGTISAPGKVVTAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQA 860
Query: 927 VTGKLFGFGASIF-SQASNLISTAGQPGP----HSQSGPGAPMKQAPAPSQPPTSQGPPK 981
TG G+S S + T Q P H AP K++P PT PP
Sbjct: 861 QTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT---PPG 917
Query: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----PPIKDSKSLT 1037
TG P+ + K++ ++E+ + E V + K P P +
Sbjct: 918 KTG-----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 972
Query: 1038 AEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPH 1097
A P +A + K+ EST +E + + T+C TP
Sbjct: 973 ATPAQAQAASTPRKARASESTARSSSSE-----SEDEDVIPATQCL-----------TP- 1015
Query: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLV 1157
G ++ MP A P+ +P +SS K + ++
Sbjct: 1016 -------------------GIRTNVVTMPTAH--PRIAPKASMAGASSSKES--SRISDG 1052
Query: 1158 KKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEE 1217
KKQE T+ + + ++ P T+ Q + +KL K K +Q+ PE
Sbjct: 1053 KKQEGPA-TQVDSAVG-------TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPES 1104
Query: 1218 KKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE 1277
++ S + EE P+ K A T P + + L + AE +
Sbjct: 1105 S-----DDSEDSSDSSSGSEEDGEGPQGAK---SAHTLGPTPSRTETLVEETA-AESSED 1155
Query: 1278 GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDK----TTKTIKEQPQPPCTAKPDQVE 1333
VAP + S ++ PK D +T K+ P AKP Q
Sbjct: 1156 DVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAA 1215
Query: 1334 PG-KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE--IPSLIPTDEKDILK 1390
KT ++ S T+ + K +G + S+ + S++ + + P +E +
Sbjct: 1216 GMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQA 1275
Query: 1391 GLKK--------------DSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKT 1436
+ K D+ + S S KL + A+ K +KK
Sbjct: 1276 SVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG------DQPAARTPRSKKKKKL 1329
Query: 1437 QPHE-----VSPEQPKDQEKTQSLSETLEITISEEEIKES------QEERKDTFKKD--- 1482
E VSPE+ K ++ + + E++ K S ++E ++ +K
Sbjct: 1330 GAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGT 1389
Query: 1483 ---SQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRR 1530
Q P SK K+KS+ ++E +++S ++ Q+K++
Sbjct: 1390 VEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKK 1440
Score = 123 bits (308), Expect = 5e-27
Identities = 317/1443 (21%), Positives = 506/1443 (35%), Gaps = 221/1443 (15%)
Query: 46 SQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPS-MHRKQELDSSHPPKQSGRPPDPGR 104
S+ SEEE A L + A+ PS M K + ++ K P P
Sbjct: 85 SESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP-- 142
Query: 105 PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALS 164
+ +T L G+SP S + S + T + E + +P F +
Sbjct: 143 ------ATGKTVANL-----LSGKSPRK-SAEPSANTTLVSETEEEGSVPAF-----GAA 185
Query: 165 AVSSVVNKFNPFDLISDSEASQEETTKKQKV-VQKEQGKPEGIIKPPLQQQPPKPIPKQQ 223
A +V+ D+ +S +ET + K V+ Q K + + P P +
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
Query: 224 GPGRDPLQQDGTPKSISSQQPEK-IKSQPPGTGKPIQGPTQTPQTDHA--KLPLQRDASR 280
G ++ P + +++PE+ +S G+ + P T A K+ R AS
Sbjct: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305
Query: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPA------ 333
P A G+ P+ P + Q GKP + E+S + PA
Sbjct: 306 P----AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQ 361
Query: 334 --------QPSGLTKPLAQQPGTVKPPVQPPGTTKPP-AQPLGPAKPPAQQTGSEKPSSE 384
Q + P + P P PPG T P A+ + Q+ SE+ SE
Sbjct: 362 AKASGKTSQVGAASAPAKESPRKGAAPA-PPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ--------QPGLQSPAKAPGP 436
+ P A A+P G PAK ++ P P + Q G Q
Sbjct: 421 EEAP-AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 479
Query: 437 TKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKP-PPQQPGPAKPPPQ-- 492
++ + + A Q P GK+ + T L A P PP + GPA P Q
Sbjct: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539
Query: 493 ---QPGSAKPPSQQPGSTKPPPQQPGPAKPSP-----QQPGSTKPPSQQPGSAKPSAQQP 544
+ + S P PA+ Q ++ P P A P A Q
Sbjct: 540 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599
Query: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT-ICP-LCNTT------- 595
KP S + S + P +A+ P+ +P+T CP NTT
Sbjct: 600 KAEKP-MDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAP 658
Query: 596 -ELLLHVPEKANFNTCTECQTTVCSLCGFNPNP----------HLTEVKEWLCLNCQMKR 644
+ P KA T T + ++ G P E K L + +
Sbjct: 659 VRVGTQAPRKA--GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 716
Query: 645 ALGGDL----APVP--------SSPQPKLKTAPVTTTSAVSK----SSPQPQQTSPKKDA 688
++G L A VP ++P KT P T K S + + S + A
Sbjct: 717 SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
Query: 689 APKQDLS--KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQD 745
+P Q + K + K P + P+ G+ SA K A + +P K +P V + Q+
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
Query: 746 KAPVADDKPKQPKMVKPTTDLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLKTDSAKPS 803
+A P + K + +++ A T P D SS+ +S +EE+ KPS
Sbjct: 837 STVLARGPASVPSVGKA---VATAAQAQTGPEEDSGSSEEESDSEEEAE---TLAQVKPS 890
Query: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK---KAQT 860
++P +K PR + GPS+ G KQ D EE +A
Sbjct: 891 GKTHQIRAALAP--AKESPRKGAAPTPPGKTGPSAAQAG-KQDDSGSSSEESDSDGEAPA 947
Query: 861 KMSPKPDAKPM-----PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA 915
++ KP P SP P P Q TP+++ + +R S
Sbjct: 948 AVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVI 1007
Query: 916 PKSQPTTP------------QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963
P +Q TP + K GAS ++S + Q GP +Q
Sbjct: 1008 PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVG 1067
Query: 964 MKQAPAP-SQPPTSQGPPK-------STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ- 1014
A +P S ++G K QA AP S + + + + + + + Q
Sbjct: 1068 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1127
Query: 1015 -------APTVKRTETEKKPPPIKDSKSLTAEPQKAVL---------PTKLEKS---PKP 1055
PT RTET + + S+ P +++L P + S PK
Sbjct: 1128 AKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKL 1187
Query: 1056 ESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAI 1115
+S+ + T + +KD P+ E K Q + L + A
Sbjct: 1188 DSSPSVSST---LAAKDDPDGK--QEAKPQ--------------QAAGMLSPKTGGKEAA 1228
Query: 1116 SGQLGDIRKMPPAPSG-PKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILE 1174
SG + P +G P+AS + + + + P + E +V+ KV+
Sbjct: 1229 SGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL-----NEAQVQASVVKVL-- 1281
Query: 1175 KVKETLSMEKIPPMVTTDQKQEES-KLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKK 1233
E L E+ + TT + + + K K S Q P KK ++K+ + E
Sbjct: 1282 --TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK----KKKLGAGEG- 1334
Query: 1234 PLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQ-EGKQPQ 1292
E +PE KTS + K K+ + E+K +G + + + E ++
Sbjct: 1335 ---GEASVSPE--------KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEEL 1383
Query: 1293 TKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQ 1352
K G G QS PK + K+ K + K + + K+K +K K S SQ
Sbjct: 1384 QKGMGTVEGGDQSNPKSKKEKKKSDKRK-------KDKEKKEKKKKAKKASTKDSESPSQ 1436
Query: 1353 QPK 1355
+ K
Sbjct: 1437 KKK 1439
Score = 96.3 bits (238), Expect = 7e-19
Identities = 247/1179 (20%), Positives = 401/1179 (34%), Gaps = 222/1179 (18%)
Query: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705
LG DL PSS + K K A S P P + + K+ EP
Sbjct: 113 LGADL---PSSMKEKAK-AETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTT 168
Query: 706 LVKQPTLHGS-PSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764
LV + GS P+ A P S + A S D+ V + KP VKP
Sbjct: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQ-ADSSSEDTSSSSDETDV-EGKPS----VKPAQ 222
Query: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQ---SFPPTGEKVSPFDSKAI 821
V +SS +TK +S A + P K P + PP P +
Sbjct: 223 --VKASSVSTK--------ESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESES 272
Query: 822 PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881
S+S+ + G S+ K +++ V+ P K P +P PPG
Sbjct: 273 SEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGT----------PGKGATPAPPGK 322
Query: 882 RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
AG V + ++ KP+E S S + + Q +GK GA+ +
Sbjct: 323 ---AG-AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAAS-AP 377
Query: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP-----------KSTGQAPPAP 990
A P P ++GP QA + S K +G+AP
Sbjct: 378 AKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 437
Query: 991 AKSIPVKKETKAPAA----EKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLP 1046
A S P K+ + AA K P A Q K+ E + DS A
Sbjct: 438 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 497
Query: 1047 TKLEKSP--KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
L KSP KP ST + G P T P+ + + +E
Sbjct: 498 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT-------------PSAQVGKWEE- 543
Query: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
++ + G++ AP+ K+ + + +S PPQ K V
Sbjct: 544 -DSESSSEESSDSSDGEV-PTAVAPAQEKSLGNILQAKPTSSPAKGPPQ----KAGPVAV 597
Query: 1165 KTEAEKVI-----LEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK 1219
+ +AEK + E+ ++ E+ P +T Q + K+ + KA +K K
Sbjct: 598 QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP--KKTNTTASAK 655
Query: 1220 LIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGR 1279
+ P +R + P +P T P E D S+ +EE+ G
Sbjct: 656 VAP----VRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAE---DSSSSEESDSEEEKTGL 708
Query: 1280 VAP--KTVQEGKQPQTKMEGLP------SGTPQSLPKEDDKTTKTIKEQPQPP------- 1324
+ GK Q K +P GT LP + T +K + Q
Sbjct: 709 AVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE 768
Query: 1325 -----CTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPS 1379
A P QV+ +KT+ K++ ++++ P + +S G + + PS
Sbjct: 769 SDSEEAAASPAQVKTSVKKTQA---KANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPS 825
Query: 1380 LIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPH 1439
+ ++ P + + LA+ ++V S+ +A A+ ++ +T P
Sbjct: 826 KVKPPVRN---------------PQNSTVLARGPASVPSVGKAVATA-----AQAQTGPE 865
Query: 1440 EVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEF 1499
E S S EE +S+EE + Q PS K H+ ++
Sbjct: 866 EDSG--------------------SSEEESDSEEEAETL-----AQVKPSGKTHQIRAAL 900
Query: 1500 VDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEED----- 1554
+ES +P P K G S++ KQ+DS S EE D
Sbjct: 901 AP-----------AKESPRKGAAPTPPGK----TGPSAAQAGKQDDSGSSSEESDSDGEA 945
Query: 1555 --------FIRKQIIEMSADEDASG-----------SEDDEFIRNQLKEISSSTESQKKE 1595
I+ +I + + +G S + ++ SSS+ES+ ++
Sbjct: 946 PAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDED 1005
Query: 1596 ETKGKGKITAG----------KHRRLTRKSS---TSIDEDAGRRHSWHDEDDEAFDESPE 1642
+T G H R+ K+S S +++ R ++ A
Sbjct: 1006 VIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSA 1065
Query: 1643 LKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEME 1702
+ S +S + G LR+ K E+ S++ S+ + +
Sbjct: 1066 VGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSS------------D 1113
Query: 1703 SLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDS 1741
S + S ED +G+ S H TP + T V +S
Sbjct: 1114 SSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAES 1152
Score = 76.6 bits (187), Expect = 6e-13
Identities = 220/1033 (21%), Positives = 346/1033 (33%), Gaps = 218/1033 (21%)
Query: 32 PSHTAIPAGMEADLSQLSEEER---RQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELD 88
P+ + G + + S+ S EE R+ A M+ AQ P G P S
Sbjct: 461 PAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM-------- 512
Query: 89 SSHPPKQSGRPPDPGR--PAQPGLSKSR-----TTDTFRSEQKLPGRSPSTISLKESKSR 141
P + P PG+ PA P + + + S G P+ ++ + KS
Sbjct: 513 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 572
Query: 142 TD-LKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQ 200
+ L+ + SS G V+ V P D SE S + ++
Sbjct: 573 GNILQAKPTSSPAKG---PPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTA 629
Query: 201 GKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKI--KSQPPGTGKPI 258
+ KP L+ K PK+ P + +Q P K + P G+ +
Sbjct: 630 AQA----KPALKIPQTKACPKKTNT---TASAKVAPVRVGTQAPRKAGTATSPAGSSPAV 682
Query: 259 QGPTQTPQTDHAKLPLQRDASRPQTKQADIVR----------------------GESVKP 296
G TQ P D + + D+ +T A V G+ P
Sbjct: 683 AGGTQRPAEDSSSSE-ESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 741
Query: 297 SLPSPSKPPIQQPTPGKPPAQQPGHE-----------------------KSQPGPAKPPA 333
LP + P + Q K + E K+ P A+ P+
Sbjct: 742 VLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 801
Query: 334 QPSGLTKP----------LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA---------- 373
++ P + P VKPPV+ P + A+ GPA P+
Sbjct: 802 AKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR--GPASVPSVGKAVATAAQ 859
Query: 374 QQTG-------SEKPSSEQPGPKALAQPPGVGKTPAQQPG--PAKPPTQQVGTPKPLAQQ 424
QTG SE+ S + + LAQ GKT + PAK ++ P P
Sbjct: 860 AQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTP---- 915
Query: 425 PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT--KPPSQLPGPAKPPPQ 482
PG P+ A +Q G + G+ A T KPP P + P
Sbjct: 916 PGKTGPSAAQAG-----KQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPA- 969
Query: 483 QPGPAKPPPQQPGSAKP----PSQQPGSTKPPPQQPGPAKPSPQ--QPGS-----TKPPS 531
GPA P Q ++ P S+ + + P+ Q PG T P +
Sbjct: 970 --GPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 1027
Query: 532 QQPGSAKPSAQQPSPAKPSAQQSTK-----PVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
+ K S S +K S++ S P +Q S P T SP + ++G K
Sbjct: 1028 HPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPAT-SPQSTSVQAKGTNK 1086
Query: 587 TICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCG-----------FNPNPHLTE--VK 633
P + PE ++ + + ++ G P P TE V+
Sbjct: 1087 LRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVE 1146
Query: 634 EWLCLNCQ------MKRALGGDLAP--VPSSPQ-----PKLKTAPVTTTSAVSKSSPQPQ 680
E + + + L G + P P++ Q PKL ++P +++ +K P +
Sbjct: 1147 ETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGK 1206
Query: 681 QTSPKKDAA----PKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS---LSKPA 733
Q + + AA PK +A P K G+P A + L +P
Sbjct: 1207 QEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPW 1266
Query: 734 PPKEPSVPS----------EQDKAPVAD-------------------DKP--KQPKMVKP 762
P E V + EQ++ V D D+P + P+ K
Sbjct: 1267 PLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKK 1326
Query: 763 TT-DLVSSSSATTKPDIPSSKVQSQAE-EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKA 820
A+ P+ S+ + +A+ +K + +K K S G K P +
Sbjct: 1327 KKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG--SQGAKDEPEEELQ 1384
Query: 821 IPRPASDSKIISHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP 876
+ S+P E K +K + +KK++ KKA TK S P K K
Sbjct: 1385 KGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKK--- 1441
Query: 877 TPPGPRPTAGQTV 889
+ TA QTV
Sbjct: 1442 ----KKKTAEQTV 1450
Score = 52.4 bits (124), Expect = 1e-05
Identities = 190/988 (19%), Positives = 330/988 (33%), Gaps = 152/988 (15%)
Query: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA-------PAAEKLEPKAEQAPTVKRTET 1023
S P ++ + +A AK+ P T + P++ K + KAE K +
Sbjct: 79 SDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
Query: 1024 EKKPPPIKDSKSLTA--EPQKAVLP---TKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078
P K +L + P+K+ P T L + E + P G ++
Sbjct: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198
Query: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP 1138
+E + + P + Q ++S + RK PAP
Sbjct: 199 SSEDTSSSSDETDVEGKPSVKPAQV-------KASSVSTKESPARKAAPAPG-------K 244
Query: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV------KETLSMEKI------- 1185
V + K P K KK E+E ++ E E+ + + EKI
Sbjct: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS 304
Query: 1186 -PPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP----LLEEKK 1240
P T + + K A A Q K PEE EE SEE+ P LL+ K
Sbjct: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
Query: 1241 -----------------------PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE 1277
P P K AK A + ++ S+ +EE+
Sbjct: 365 SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424
Query: 1278 GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPD--QVEPG 1335
+ P GK PQ + P+ K + P PP P QV+ G
Sbjct: 425 AQAKPS----GKAPQVRAASAPA-----------KESPRKGAAPAPPRKTGPAAAQVQVG 469
Query: 1336 KEKTEKEDDKSDTSSSQQP-------------KSPQGLSDTGYSSDGISSSLGEIP--SL 1380
K++ + ++ S ++ KSPQ + + G +P +
Sbjct: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
Query: 1381 IPTDEKDILKGLKKDS--FSQESSPSSPSDLAKL-----ESTVLSILEAQASTLADEKSE 1433
P + ++DS S+ESS SS ++ E ++ +IL+A+ ++ +
Sbjct: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
Query: 1434 KKTQPHEVSPEQPKDQEKTQSLSETLEITISEEE-IKESQEERKDTFKKDSQQDIPSSKD 1492
+K P V + K + ++S E+ + SEE + + K K + P +
Sbjct: 590 QKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
Query: 1493 HKEKSEFVDDITTRREPYDSVEESSESENSP-VPQRKRRTSVGSSSSDEYKQEDSQGSGE 1551
++ + P + +S + +SP V +R + SSSS+E S
Sbjct: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE--------SDS 701
Query: 1552 EEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL 1611
EE+ + A G + + +++ K +G + GK
Sbjct: 702 EEEKTGLAVTVGQAKSVGKGLQ-----------VKAASVPVKGSLGQGTAPVLPGKTGPT 750
Query: 1612 TRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIE 1671
+ ED+ S + D E SP K +++ R + +
Sbjct: 751 VTQVKAEKQEDS--ESSEEESDSEEAAASPAQVKTSVKKTQAK-----ANPAAARAPSAK 803
Query: 1672 LNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSP 1731
+ K ++Q K P + + G +S+ + T+
Sbjct: 804 GTISAPGKVVTAAAQAK-----QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
Query: 1732 TSVSSLDEDSDSSPSHKKGESKQQRKARHRPHG-------PLLPTIEDSSEEEELREEEE 1784
+ + +EDS SS E + + A+ +P G L P E S +
Sbjct: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE--SPRKGAAPTPP 916
Query: 1785 LLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP----PSNLSPIEDASPTE 1840
+ +Q SSS++S D + A + K P N SP A+
Sbjct: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
Query: 1841 ELRQAAEMEELHRSSCSEYSPSIESDPE 1868
+ + A+ + S + S S ES+ E
Sbjct: 977 QAQAASTPRKARASESTARSSSSESEDE 1004
Score = 52.0 bits (123), Expect = 2e-05
Identities = 119/646 (18%), Positives = 233/646 (36%), Gaps = 77/646 (11%)
Query: 1299 PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKP----DQVEPGKEKTEKEDDKSDTSSSQQP 1354
P T +S +E++ +T K P+ T D KEK + E +K+ + + P
Sbjct: 81 PISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMP 140
Query: 1355 --------------KSPQGLSDTGYSSDGISSSL--GEIPSLIPTDEKDILKGLKKDSFS 1398
KSP+ ++ ++ +S + G +P+ + ++ + DS S
Sbjct: 141 HPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSS 200
Query: 1399 QESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSET 1458
+++S SS + + +V +S E +K P Q K +L
Sbjct: 201 EDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPA 260
Query: 1459 LEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSE 1518
EEE + S+E +S+++ P+ + K+ + I R + +
Sbjct: 261 KRAKKPEEESESSEE------GSESEEEAPAGTRSQVKAS--EKILQVRAASAPAKGTPG 312
Query: 1519 SENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFI 1578
+P P K +V S + +EDS+ S EE ++ A A S
Sbjct: 313 KGATPAPPGK-AGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKAS------ 365
Query: 1579 RNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFD 1638
+ ++ +++ K+ KG GK K+ AG+R +ED ++
Sbjct: 366 -GKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKA------QAGKR----EEDSQSSS 414
Query: 1639 ESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIAD-KYSAESSQKKT--SLYFDE 1695
E E+ S+E G + + + + K +A + +KT + +
Sbjct: 415 E-------ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
Query: 1696 EPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQ 1755
+ E +S + S E S E ++++A+ P L + P+ G
Sbjct: 468 VGKQEEDSRSSSEESDSDREALAAMNAAQVKP---------LGKSPQVKPASTMGMGPLG 518
Query: 1756 RKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELR 1815
+ A P G + P S++ + E+ E E+ + + + K + L+
Sbjct: 519 KGAGPVPPGKVGPA-TPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ 577
Query: 1816 AQRRRERPKTPPSNLSPI----------EDASPTEELRQAAEMEELHRSSCSEYSPSIES 1865
A+ K PP P+ +++ +EE +A+ EE + + +
Sbjct: 578 AKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALK 637
Query: 1866 DPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKAL 1911
P+ + P+K P V +P + GS A+
Sbjct: 638 IPQ-TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAV 682
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 125 bits (313), Expect = 1e-27
Identities = 183/739 (24%), Positives = 269/739 (36%), Gaps = 101/739 (13%)
Query: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP---AQQTGSEKPSSEQPGPKALAQPPGV 397
P A+ PG + P +PPG+ +PP P+ PA A KP +E+ G G+
Sbjct: 17 PAARAPGLLTP--RPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAG--------GI 65
Query: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ--PGPGKIPAQQAG 455
G + P PT+ GT ++ P + PA G P + PGP P + +G
Sbjct: 66 GGATIPESAPRAGPTRSAGTS---SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
Query: 456 ---PG-------KTSAQQT----GPTKPP--SQLPGPAKPPPQQPGPAKPPPQQPGSAKP 499
PG + SA++T T+ P S L A+ P P P P ++
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
Query: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA---KPSAQQST- 555
+ G +P P A+P P G K S +++ S +PSPA +PSA
Sbjct: 183 AGTEVGLPRPAPS----ARPRPPTEGPRKSVSS---ASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 556 KPVSQT--GSGKPLQPPTVS-------PSAKQPPSQGLPK---TICPLCNTTELLLHVPE 603
+P S++ S PL P S P A PSQ PK + P T P
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
Query: 604 KANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT 663
++ + + P L L CQ+ L LAP S P L+T
Sbjct: 296 LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL--PLAPPSPSAPPSLQT 353
Query: 664 APVTTTSAVSKS-----SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
P + S++ SP Q T + P L A P + PP + P L PS
Sbjct: 354 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL--ATPPPQAPPALALPPLQAPPSP 411
Query: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSS---ATTK 775
A P + P P +V Q P Q P + VS S+ +
Sbjct: 412 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 471
Query: 776 PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP- 834
P + + +Q +PP+ + P Q+ PP +P A P P + + + P
Sbjct: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA---APPLQLAKPPPQAPPALATPPL 528
Query: 835 ----GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVP 890
P + GQ P A +P P A P+ P P A T+
Sbjct: 529 QALPSPPASFPGQAPFSPSASLPMSPLA----TPPPQAPPVLAAPLLQVPPSPPASPTLQ 584
Query: 891 TPQQSPKPQEQSR----RFSLNLGSITDAPKSQPTTPQETVTGK-LFGFGASIFSQASNL 945
P++ P P + R +L L P S+ +P T++G L G +S S L
Sbjct: 585 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR--SPSSTLSGPDLAGHSSSATSTPEEL 642
Query: 946 IS--------TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPA----PAKS 993
A P P ++ P + P+ P +G P + PPA A
Sbjct: 643 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 702
Query: 994 IPVKKETKAPAAEKLEPKA 1012
+ ET+ P + P A
Sbjct: 703 LCTIYETEGPESATPAPGA 721
Score = 124 bits (312), Expect = 2e-27
Identities = 173/626 (27%), Positives = 225/626 (35%), Gaps = 98/626 (15%)
Query: 28 GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP---PAAAESPSMHRK 84
G+ P PA + L R+ +A RA G+ ++P P A + S
Sbjct: 31 GSPRPPPPVTPAALRV-LGAAGAVGRKPLA---ERAGGIGGATIPESAPRAGPTRSAGTS 86
Query: 85 QELDSSHPPKQSGR----PPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKS 140
+S PP SGR PP P S R + T R G+ IS +E+ +
Sbjct: 87 SRNPASRPPA-SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL--GQKGLRISAEETVA 143
Query: 141 RTDLKEEHKSSMM------------PGFLSEVNALS--AVSSVVNKFNPFDLI------- 179
R E K S + PG S A A + V P
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
Query: 180 ----SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ---------QPPKPIPKQQGPG 226
S S AS+ TT+ ++ G+ +P + P + P +G
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
Query: 227 RDPLQ-QDGTPKSISSQQPEKI----KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281
R P PK + + +P ++ K P G P TP A L Q + P
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS-AALQSQAPPTLP 322
Query: 282 QTKQADIVRGESVKP---SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL 338
T + + + P + PSPS PP Q P PPA P + G A S L
Sbjct: 323 ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS-PPATPPSQATTSLGSPTLQATHSFL 381
Query: 339 TKPLAQQPGTVKPPVQPPGTTKPPAQ--PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG 396
P P PP PP PP Q P PA PP + P + P ALA
Sbjct: 382 PSP-PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA----PNALA---- 432
Query: 397 VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP-GPTKTPVQQPGPG-KIPAQQA 454
V A P PP Q +P PA P P+ TP Q P P Q
Sbjct: 433 VHLLQAPFSPPPSPPVQAPFSP-----------PASPPVSPSATPPSQAPPSLAAPPLQV 481
Query: 455 GPGKTSAQQTGPTK-PPSQLPGPAKPPPQQPGPAKPPPQQPGS-AKPPSQQPGSTKPPPQ 512
P ++ P+ PP Q P P PP Q AKPPPQ P + A PP Q S PP
Sbjct: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQL--AKPPPQAPPALATPPLQALPS--PPAS 537
Query: 513 QPG--PAKPS---PQQPGSTKPPSQQPGSAKPSAQQPS--PAKPSAQQSTKPVS---QTG 562
PG P PS P P +T PP P A P Q P PA P+ Q +P + T
Sbjct: 538 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 597
Query: 563 SGKPLQPPTVSPSAKQPPSQGLPKTI 588
P ++P PPS+ T+
Sbjct: 598 VSGPRLTLALAPGPPPPPSRSPSSTL 623
Score = 117 bits (294), Expect = 2e-25
Identities = 175/728 (24%), Positives = 262/728 (35%), Gaps = 107/728 (14%)
Query: 227 RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
RD + ++ +++ P + +PPG+ +P P TP +P ++A
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 287 DIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP 346
+ G ++ S P P T + PA +P S G PPA+ + P
Sbjct: 63 GGIGGATIPESAPRAG-PTRSAGTSSRNPASRP--PASGRGERAPPAKNTS--------P 111
Query: 347 GTVKPPVQPPGTTKPPAQPLGPA--KPPAQQTGSEKPSSEQPGPKAL---AQPPGVGKTP 401
G V P + GTT+P PLG + A++T + ++E P AL A+ G TP
Sbjct: 112 GPVSSPGRASGTTRPG--PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP 169
Query: 402 AQQPGPA-----KPPTQQVGTPKPLAQ---QPGLQSPAKA-PGPTKTPVQQPGPGKIPAQ 452
P PA + +VG P+P +P + P K+ ++ +P P
Sbjct: 170 GT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 228
Query: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP--PQQPGSAKPPSQQPGSTKPP 510
AG G + + L PA+ P G + P P QP + +P PP
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288
Query: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
+ PA P S+ P + SA +Q P P P+ S+ Q + PL PP
Sbjct: 289 RKDAAPALG----PLSSSPLATPSPSAALQSQAP-PTLPATPHSSSLTCQLATPLPLAPP 343
Query: 571 TVS--PSAKQ-------PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC 621
+ S PS + PPSQ P T L P + T +L
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403
Query: 622 GFN--PNPHLTEVKEWLCL-NCQMKRALGGDLAPVPSSPQPKLK---------TAPVTTT 669
P+P + L + Q AL L P SP P + PV+ +
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463
Query: 670 SAVSKSSPQ-----PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
+ +P P Q P A+P S P P+ PPPL P AK PP
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA------APPLQLAKPPP 517
Query: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
+ APP + P + +P A + P P+ L S AT P P
Sbjct: 518 Q-------APPALATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAA 568
Query: 785 SQAEEKTTPPLKTDSAKPSQSFPPT--------GEKVSPFDSKAIPRPASDSKIISHPGP 836
+ +PP P + PPT G +++ + P P S S + GP
Sbjct: 569 PLLQVPPSPPASPTLQAPRR--PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626
Query: 837 ---SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK------------PMP----KGSPT 877
S + ++ + + SP PDA+ P P +G+P
Sbjct: 627 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 686
Query: 878 PPGPRPTA 885
P P P A
Sbjct: 687 APLPWPPA 694
Score = 112 bits (280), Expect = 9e-24
Identities = 151/579 (26%), Positives = 202/579 (34%), Gaps = 74/579 (12%)
Query: 5 ASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQ 64
AS GE P A + G S G S T P + ++S EE +A
Sbjct: 96 ASGRGERAPP---AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE----TVARGKAT 148
Query: 65 GLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK 124
PK S A A + SG P PG P+ +SR T E
Sbjct: 149 EAPKRSALSAGARRDT---------------SG--PTPGTPSPAMARRSRAAGT---EVG 188
Query: 125 LPGRSPSTISLKES----KSRTDLKEEHKSSMMPGFLSEVNA-----LSAVSSVVNKFNP 175
LP +PS + KS + E + P +A A S+ + P
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 176 FDLISDSEASQEETTKKQKVVQKEQGKPEGI--IKPPLQQQPPKPIPKQQGP-GRDPLQQ 232
+ S S T + Q KP+G+ ++PP P K GP PL
Sbjct: 249 LSSPARSGPSARGTPRAP--AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306
Query: 233 DGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ---TPQTDHAKLPLQRDASRPQT--KQAD 287
++ SQ P + + P + Q T P + A LQ S P T QA
Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT 366
Query: 288 IVRG----ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP-AKPPAQPSGLTKPL 342
G ++ LPSP P+ P P PPA ++ P P A PP P L P
Sbjct: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP--LATPS 424
Query: 343 AQQPGTVKPPVQPPGTTKPPAQPL-GPAKPPAQQTGSEKPSSEQPGPKALAQPP-GVGKT 400
Q P + + + PP+ P+ P PPA S + P +LA PP V +
Sbjct: 425 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 484
Query: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS 460
P PA PP TP P A P P + P P Q P P QA P
Sbjct: 485 P-----PASPPMSPSATPPPQAPPPLAAPPLQLAKP---PPQAPPALATPPLQALPS--- 533
Query: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520
PP+ PG A P P P P A P P PP P +
Sbjct: 534 --------PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
Query: 521 PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559
P++P + P + G A P P P ++ + +S
Sbjct: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 624
Score = 109 bits (273), Expect = 6e-23
Identities = 193/770 (25%), Positives = 261/770 (33%), Gaps = 140/770 (18%)
Query: 190 TKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGT--PKSISSQQPEKI 247
T + + G PP + P P+ PGR GT P + +
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPV---SSPGR----ASGTTRPGPLGQKGLRIS 137
Query: 248 KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS-----RPQTKQADIVRGESVKPSLPSPS 302
+ GK + P ++ + A+ RD S P A R + LP P+
Sbjct: 138 AEETVARGKATEAPKRSALSAGAR----RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193
Query: 303 -----KPPIQQPTPGKPPAQQPGHEKSQPGPA--KPPAQPSGLTKPLAQQPGTVKPPVQP 355
+PP + P A + H ++P PA + P+ GL +P ++ + P+
Sbjct: 194 PSARPRPPTEGPRKSVSSASE--HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251
Query: 356 PGTTKPPAQ--PLGPAKPPAQQTGSEKPSSEQPGPKALA--QPPGVGKTPAQQPGPAKPP 411
P + P A+ P PA P QP PK L +PP V P + PA P
Sbjct: 252 PARSGPSARGTPRAPAHP------------SQPKPKGLQALRPPQV-TPPRKDAAPALGP 298
Query: 412 --TQQVGTPKPLAQQPGLQSPAKAPGP----------TKTPVQQPGPGKIPAQQAGPGKT 459
+ + TP P A P P T P+ P P P+ Q P
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP- 357
Query: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPA-KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK 518
P PPSQ P Q + P P A PP Q P + PP Q P+
Sbjct: 358 ------PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 411
Query: 519 PS--PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
P+ P P +T P A Q P PS P Q P PP VSPSA
Sbjct: 412 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS------PPVQAPFSPPASPP-VSPSA 464
Query: 577 KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWL 636
PPSQ P P L VP + T P P
Sbjct: 465 -TPPSQAPPSLAAP-------PLQVPPSPPASPPMSPSAT--------PPPQAP------ 502
Query: 637 CLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSK 696
A LA P P L T P+ + S P SP + P L
Sbjct: 503 ----PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA-SLPMSPL-- 555
Query: 697 APEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEP----SVPSEQDKAPVADD 752
A P + PP++ P L PS PP + +L P P P SV + +A
Sbjct: 556 ATPPPQAPPVLAAPLLQVPPS-----PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
Query: 753 KPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKP----SQSFPP 808
P P S SS + PD+ S + T L+ + P + S PP
Sbjct: 611 PPPPPSR--------SPSSTLSGPDLAG---HSSSATSTPEELRGYDSGPEGGAAASPPP 659
Query: 809 TGEKVSPFDSKAIPRPASDSKIISHPG---PSSESKGQKQVD---PVQKKEEPKKAQTKM 862
E + + PA PG P + G D + + E P+ A
Sbjct: 660 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESA---- 715
Query: 863 SPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSI 912
+P P A P SP G + AG +SPK Q+R L LG++
Sbjct: 716 TPAPGALD-PGPSPGTSGGKAAAGAGAGASSRSPK---QARLGELPLGAL 761
Score = 81.3 bits (199), Expect = 2e-14
Identities = 147/642 (22%), Positives = 219/642 (34%), Gaps = 97/642 (15%)
Query: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP--SAQQPSPAKPSAQQ-- 553
K + G+ P P +P+ PGS +PP +A A KP A++
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
Query: 554 ----STKPVSQTGSGKPLQPPTVSPS-AKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
+T P S +G T S + A +PP+ G + P NT+ + P +A+
Sbjct: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 609 T----------CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ 658
T + TV TE + L+ +R G P P +P
Sbjct: 124 TRPGPLGQKGLRISAEETVA-------RGKATEAPKRSALSAGARRDTSG---PTPGTPS 173
Query: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
P + + V P P P++ +S A E P P PSA
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP---SPAARRRPSA 230
Query: 719 -KAKQPPEADSLSKPAPPKEP---SVPSEQ--DKAPVADDKPK--------QPKMVKPTT 764
Q P + SLS A P S PS + +AP +PK P++ P
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 765 DLVSS----SSATTKPDIPSSKVQSQAEE--KTTP---PLKTDSAKPSQSFPPTGEKVSP 815
D + SS+ PS+ +QSQA TP L A P PP+ +P
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS--AP 348
Query: 816 FDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKP---MP 872
+ +P P + + P ++ S G + +P P A P +P
Sbjct: 349 PSLQTLPSPPA-----TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403
Query: 873 --KGSPTPPGPRPTAGQTVPTPQ----------QSPKPQEQSRRFSLNLGSITDAPKSQP 920
+ P+PP P + P+PQ Q+P S P S
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463
Query: 921 TTPQETVTGKLFGFGASI--FSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTS 976
TP L + AS +S + P P + AP Q P P PP
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523
Query: 977 QGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSL 1036
PP QA P+P S P + A+ + P A P + PP+ + L
Sbjct: 524 ATPPL---QALPSPPASFPGQAPFSPSASLPMSPLATPPP---------QAPPVLAAPLL 571
Query: 1037 TAEPQKAVLPT----KLEKSPKPESTCPLCKTELNIGSKDPP 1074
P PT + +P P+++ + L + PP
Sbjct: 572 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613
Score = 62.4 bits (150), Expect = 1e-08
Identities = 88/346 (25%), Positives = 128/346 (36%), Gaps = 52/346 (15%)
Query: 2344 PSSVIALPMKEQLSTTYFTSGETFGQEKP---ASQLPSGSPSVSSLPAKPR--PFFRSSS 2398
PS+ + L T +S T P A PS PS+ +LP+ P P ++S
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
Query: 2399 LDI-------SAQPPPPPPPPPPPPPPPPP---------PPPPPLPPPTSPKPTILPKKK 2442
L S P PP P PPP PP PP PP PP SP T P+
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ-- 426
Query: 2443 LTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPK---PSSIPSGLVF 2499
+P A L A + + +++ P A PPV P PS P L
Sbjct: 427 ----APNALAVHLLQAPFSPPPSPPVQAPFSP------PASPPVSPSATPPSQAPPSLAA 476
Query: 2500 THRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT-LNLVTSADYKLPSP- 2557
P PP +P P+ P Q P + P L+ L T LPSP
Sbjct: 477 PPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535
Query: 2558 -----TSPLSPHSN------KSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPL 2606
+P SP ++ + P + + ++ PS P +PT + + T P
Sbjct: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 595
Query: 2607 GSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATP 2652
S S +++ + PP P S+ ++G + ++TP
Sbjct: 596 TSVSGPRLTL--ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 639
Score = 57.8 bits (138), Expect = 3e-07
Identities = 89/355 (25%), Positives = 127/355 (35%), Gaps = 64/355 (18%)
Query: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
PP + P K+ S P++ L S +P +LPA P SSSL
Sbjct: 282 PPQ--VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP--TLPATPH----SSSLTCQ 333
Query: 2403 -AQPPPPPPPPPPPPPP----PPPPPPPP------------------LP-PPTSPKPTIL 2438
A P P PP P PP P PP PP LP PP SP T
Sbjct: 334 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 393
Query: 2439 PKKKLTVASPVTTATPLFDA---VTTLETTAVLRSNGLPVTRI-CTTAPPPVPPKPSSIP 2494
P+ +A P A P A ++ L T + N L V + +PPP PP +
Sbjct: 394 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF- 452
Query: 2495 SGLVFTHRPEPSKPPIAPKPVIPQL--PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADY 2552
P+ PP++P P P+ P + P P +S ++ +
Sbjct: 453 --------SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP-----PASPPMSPSATPPP 499
Query: 2553 KLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGT---PTDSSASQAITSWPLGSP 2609
+ P P + K P+ +L T + LPS P + S S ++ PL +P
Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
Query: 2610 --------SKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAP 2656
+ L+ V P P + A P + +SG T + P P
Sbjct: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613
Score = 57.0 bits (136), Expect = 5e-07
Identities = 96/372 (25%), Positives = 136/372 (36%), Gaps = 60/372 (16%)
Query: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP------PPPPPPPPPP 2421
G ++PAS+ S S + S PA+ P R + A P P P PP PP
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTP-RAPAHPSQPKPKGLQALRPPQVTPPRKD 291
Query: 2422 PPPPPLPPPTSPKPTILPKKKL-TVASPVTTATPLFDAVT-TLETTAVLR--SNGLPVTR 2477
P P +SP T P L + A P ATP ++T L T L S P +
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSL 351
Query: 2478 ICTTAPPPVPPKPSSIPSG---LVFTHR--PEPSKPPIA-PKPVIPQLPTTTQKPTDIHP 2531
+PP PP ++ G L TH P P P+A P P P P P P
Sbjct: 352 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP--PALALPPLQAPP 409
Query: 2532 KP------TGLSLTSSMTLNLVTSADYKLPSPTSP------LSPHSNKSSPRFSKSLTET 2579
P + L+ S N + A + L +P SP +P S +SP S S T
Sbjct: 410 SPPASPPLSPLATPSPQAPNAL--AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT-- 465
Query: 2580 YVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTF 2639
P P+ ++ + P SP S P PP+ A + ++
Sbjct: 466 ------PPSQAPPSLAAPPLQVPPSPPASPPMS-PSATPPPQAPPPLAAPPLQLAKPPP- 517
Query: 2640 YISGALQTFSATPVTAPSSFQAAPTSVTQF-------LTTEVSKTEVSATRSTAPSVGLS 2692
A P A QA P+ F + + + ++ AP V L+
Sbjct: 518 ---------QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV-LA 567
Query: 2693 SISITIPPEPLA 2704
+ + +PP P A
Sbjct: 568 APLLQVPPSPPA 579
Score = 53.5 bits (127), Expect = 5e-06
Identities = 74/305 (24%), Positives = 107/305 (35%), Gaps = 67/305 (21%)
Query: 2395 RSSSLDISAQPPPPPPPPPPPPP---------------PPPPPPPPPLPPPTSPKPTI-- 2437
+ S+L A+ P P P P P P P P PP P+ ++
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 211
Query: 2438 LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-----PPVPPKPSS 2492
+ T SP P + L S+ P++ + P P P PS
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271
Query: 2493 -IPSGLVFTHRPEPSKP---------PIAPKPVIPQLPTT---TQKPTDIHPKPTGLSLT 2539
P GL P+ + P P++ P+ P+ +Q P + P +
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH----S 327
Query: 2540 SSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQ 2599
SS+T L T PSP++P S + TLPS P TP SQ
Sbjct: 328 SSLTCQLATPLPLAPPSPSAPPS-------------------LQTLPSPPATP----PSQ 364
Query: 2600 AITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSF 2659
A TS LGSP+ + F PP++ + P LQ + P + P S
Sbjct: 365 ATTS--LGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 419
Query: 2660 QAAPT 2664
A P+
Sbjct: 420 LATPS 424
Score = 34.7 bits (78), Expect = 2.5
Identities = 38/141 (26%), Positives = 55/141 (39%), Gaps = 10/141 (7%)
Query: 3576 QSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKA 3635
Q+P A+ P P+P + + A +Q SPP SP V +P SP +
Sbjct: 406 QAPPSPPASPPLSPLATPSP----QAPNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPV 460
Query: 3636 LESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRA 3695
SA P + P P +P + P PPASP + P PL+ + ++
Sbjct: 461 SPSATPPSQAP-PSLAAPPLQVPPS----PPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515
Query: 3696 PFQYTEGYTTKGSQTMTSSGA 3716
P Q T Q + S A
Sbjct: 516 PPQAPPALATPPLQALPSPPA 536
Score = 33.5 bits (75), Expect = 5.6
Identities = 32/125 (25%), Positives = 46/125 (36%), Gaps = 3/125 (2%)
Query: 3573 SDTQSPQYLSATSPPKDKK-RPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLS 3631
S SP + SPP P+ + A +Q+ PSPP SP + S P
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500
Query: 3632 PGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691
L + + KP P +P + P + +P S S P+SP A
Sbjct: 501 APPPLAAPPLQLAKPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
Query: 3692 SSRAP 3696
+AP
Sbjct: 559 PPQAP 563
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 124 bits (312), Expect = 2e-27
Identities = 155/606 (25%), Positives = 222/606 (36%), Gaps = 97/606 (16%)
Query: 28 GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQEL 87
G+ P PA + L R+ +A RA G+ ++P +A +
Sbjct: 31 GSPRPPPPVTPAALRV-LGAAGAVGRKPLA---ERAGGIGGATIPESAPRAG-------- 78
Query: 88 DSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEE 147
P ++ RPP GR + +K+ + S PGR+ T + + L+
Sbjct: 79 -----PTRTSRPPASGRGERAPPAKNTSPGPVSS----PGRASGT-TRPGPLGQKGLRIS 128
Query: 148 HKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEET-TKKQKVVQKEQGKPEGI 206
+ ++ G +E SA+S+ + D + + ++ + E G P
Sbjct: 129 AEETVARGKATEAPKRSALSAGARR----DTSGPTPGTPSPAMARRSRAAGTEVGLPR-- 182
Query: 207 IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQ 266
P P + + P P + + S+ +P + P G +Q P
Sbjct: 183 ---------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233
Query: 267 TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
+ A PL A + RG P+ PS KP Q +PP P + + P
Sbjct: 234 SSSAT-PLSSPA-----RSGPSARGTPRAPAHPSQPKPKGLQAL--RPPQVTPPRKDAAP 285
Query: 327 --GP--AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGP-AKPPAQQTGSEKP 381
GP + P A PS P P +++ PP T PP+Q P Q T S P
Sbjct: 286 ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT--PPSQATTSLGSPTLQATHSFLP 343
Query: 382 SSE-----QPGPKALAQPPGVGKTPAQQPG--PAKPPTQQVGTPKPLAQQPGLQSPAKAP 434
S P P+A PP + P Q P PA PP + TP P A +AP
Sbjct: 344 SPPLSPLATPPPQA---PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400
Query: 435 --GPTKTPVQQP---------GPGKIPAQQAGPGKTSAQQTGPTKPPSQLP--GPAKPPP 481
P PVQ P P P QA P + P PP+ P A PPP
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460
Query: 482 QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS--------------PQQPGST 527
Q P P PP Q AKPP Q P + PP Q P+ P+ P P +T
Sbjct: 461 QAPPPLAAPPLQ--LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 518
Query: 528 KPPSQQPGSAKPSAQQPS--PAKPSAQQSTKPVS---QTGSGKPLQPPTVSPSAKQPPSQ 582
PP P A P Q P PA P+ Q +P + T P ++P PPS+
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578
Query: 583 GLPKTI 588
T+
Sbjct: 579 SPSSTL 584
Score = 113 bits (282), Expect = 6e-24
Identities = 176/718 (24%), Positives = 256/718 (35%), Gaps = 126/718 (17%)
Query: 227 RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
RD + ++ +++ P + +PPG+ +P P TP +P ++A
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 287 DIVRGESVKPSLPSPSKPPIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ 345
+ G ++ P P PT +PPA S G PPA+ +
Sbjct: 63 GGIGGATI------PESAPRAGPTRTSRPPA-------SGRGERAPPAKNTS-------- 101
Query: 346 PGTVKPPVQPPGTTKPPAQPLGPA--KPPAQQTGSEKPSSEQPGPKAL---AQPPGVGKT 400
PG V P + GTT+P PLG + A++T + ++E P AL A+ G T
Sbjct: 102 PGPVSSPGRASGTTRPG--PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 159
Query: 401 PAQQPGPA-----KPPTQQVGTPKPLAQ---QPGLQSPAKA-PGPTKTPVQQPGPGKIPA 451
P P PA + +VG P+P +P + P K+ ++ +P P
Sbjct: 160 PGT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 218
Query: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP--PQQPGSAKPPSQQPGSTKP 509
AG G + + L PA+ P G + P P QP + +P P
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 278
Query: 510 PPQQPGPAK-PSPQQPGSTKPPSQQPG-SAKPSAQQ-PSP-AKPSAQQSTKPVSQT--GS 563
P + PA P P +T PS P SA PS Q PSP A P +Q +T S T +
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338
Query: 564 GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGF 623
L P +SP A PP Q P P P + T
Sbjct: 339 HSFLPSPPLSPLATPPP-QAPPALALPPLQAPPSPPASPPLSPLAT-------------- 383
Query: 624 NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ----- 678
P+P N L +P PS P + P + + S + P
Sbjct: 384 -PSPQAP--------NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 434
Query: 679 ----PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAP 734
P Q P A+P S P P+ PPPL P AK PP+ AP
Sbjct: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA------APPLQLAKPPPQ-------AP 481
Query: 735 PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPP 794
P + P + +P A + P P+ L S AT P P + +PP
Sbjct: 482 PALATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539
Query: 795 LKTDSAKPSQSFPPT--------GEKVSPFDSKAIPRPASDSKIISHPGP---SSESKGQ 843
P + PPT G +++ + P P S S + GP S
Sbjct: 540 ASPTLQAPRR--PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597
Query: 844 KQVDPVQKKEEPKKAQTKMSPKPDAK------------PMP----KGSPTPPGPRPTA 885
+ ++ + + SP PDA+ P P +G+P P P P A
Sbjct: 598 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 655
Score = 108 bits (270), Expect = 1e-22
Identities = 178/746 (23%), Positives = 268/746 (35%), Gaps = 154/746 (20%)
Query: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP---AQQTGSEKPSSEQPGPKALAQPPGV 397
P A+ PG + P +PPG+ +PP P+ PA A KP +E+ G G+
Sbjct: 17 PAARAPGLLTP--RPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAG--------GI 65
Query: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK---APGPTKTPVQQPG---PGKIPA 451
G + P PT+ T +P A G ++P +PGP +P + G PG P
Sbjct: 66 GGATIPESAPRAGPTR---TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG--PL 120
Query: 452 QQAGPGKTSAQQT----GPTKPP--SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505
Q G + SA++T T+ P S L A+ P P P P ++ + G
Sbjct: 121 GQKGL-RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 179
Query: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565
+P P A+P +PP++ P + SA + S +PS +P + G +
Sbjct: 180 LPRPAPS----ARP--------RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 227
Query: 566 PLQ-------PPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVC 618
P P SP+ P ++G P+ Q
Sbjct: 228 PASRSLSSSATPLSSPARSGPSARGTPRA---------------------PAHPSQPKPK 266
Query: 619 SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTS---AVSKS 675
L P P +T ++ D AP L ++P+ T S S S
Sbjct: 267 GLQALRP-PQVTPPRK--------------DAAPALGP----LSSSPLATPSPSAPPSPS 307
Query: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP--SAKAKQPPEA-DSLSKP 732
+P QT P A P S+A P L + SP S A PP+A +L+ P
Sbjct: 308 APPSLQTLPSPPATPP---SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 364
Query: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
PS P+ +P+A P+ P + V A P PS VQ+ +
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNAL-----AVHLLQAPFSPP-PSPPVQAPFSPPAS 418
Query: 793 PPLKTDSAKPSQS----------FPPTGEKVSPFDSKAIPRPASDSKIISHP----GPSS 838
PP+ + PSQ+ PP+ P A P P + + + P P
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478
Query: 839 ESKGQKQVDPVQKKEEPKKA---QTKMSPKPDAKPMPKGSPTPPG------------PRP 883
++ P+Q P + Q SP P +P P P P
Sbjct: 479 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538
Query: 884 TAGQTVPTPQQSPKPQEQSR----RFSLNLGSITDAPKSQPTTPQETVTG-KLFGFGASI 938
A T+ P++ P P + R +L L P S+ +P T++G L G +S
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR--SPSSTLSGPDLAGHSSSA 596
Query: 939 FSQASNLI--------STAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPA- 989
S L A P P ++ P + P+ P +G P + PPA
Sbjct: 597 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 656
Query: 990 ---PAKSIPVKKETKAPAAEKLEPKA 1012
A + ET+ P + P A
Sbjct: 657 GPGSADGLCTIYETEGPESATPAPGA 682
Score = 105 bits (262), Expect = 1e-21
Identities = 108/408 (26%), Positives = 146/408 (35%), Gaps = 49/408 (12%)
Query: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ---------QPPKPIPKQQGPGRDPL 230
S S AS+ TT+ ++ G+ +P + P + P +G R P
Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258
Query: 231 Q-QDGTPKSISSQQPEKI----KSQPPGTGKPIQGPTQTPQTDHAKLP-----LQRDASR 280
PK + + +P ++ K P G P TP P LQ S
Sbjct: 259 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP 318
Query: 281 PQT--KQADIVRG----ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP-AKPPA 333
P T QA G ++ LPSP P+ P P PPA ++ P P A PP
Sbjct: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378
Query: 334 QPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL-GPAKPPAQQTGSEKPSSEQPGPKALA 392
P L P Q P + + + PP+ P+ P PPA S + P +LA
Sbjct: 379 SP--LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 436
Query: 393 QPP-GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA 451
PP V +P PA PP TP P A P P + P P Q P P
Sbjct: 437 APPLQVPPSP-----PASPPMSPSATPPPQAPPPLAAPPLQLAKP---PPQAPPALATPP 488
Query: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP 511
QA P PP+ PG A P P P P A P P PP
Sbjct: 489 LQALPS-----------PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 537
Query: 512 QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559
P +P++P + P + G A P P P ++ + +S
Sbjct: 538 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 585
Score = 99.4 bits (246), Expect = 8e-20
Identities = 141/590 (23%), Positives = 192/590 (32%), Gaps = 82/590 (13%)
Query: 16 LAAAAAAGGGASGAGSPSHTAIPA----GMEADLSQLSEEERRQIAAVMSRAQGLPKGSV 71
+A + A G G P+ +A P G +S SE + + R G
Sbjct: 167 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 226
Query: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR--- 128
PA+ S + P G P P P+QP K + R Q P R
Sbjct: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP---KPKGLQALRPPQVTPPRKDA 283
Query: 129 SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEE 188
+P+ L S T S P L + + A + + S
Sbjct: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343
Query: 189 TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIK 248
+ + P + PPLQ P P P P Q P +++ +
Sbjct: 344 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ--APNALAVHLLQAPF 401
Query: 249 SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308
S PP P+Q P P A P+ A+ P PS + PP+Q
Sbjct: 402 SPPPSP--PVQAPFSPP----ASPPVSPSATPPSQAP-------------PSLAAPPLQ- 441
Query: 309 PTPGKPPAQQPGHEKSQPGPAKPP---AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP 365
P PPA P + P P PP A P L KP PP PP PP Q
Sbjct: 442 -VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP---------PPQAPPALATPPLQA 491
Query: 366 LGPAKPPAQQTGSE--KPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
L PPA G PS+ P PP Q P P QV P P A
Sbjct: 492 L--PSPPASFPGQAPFSPSASLPMSPLATPPP-------QAPPVLAAPLLQV-PPSPPAS 541
Query: 424 QPGLQSPAKAP---------GPTKTPVQQPGPGKIPAQQ-----AGPGKTSAQQTGPTKP 469
P LQ+P + P GP T PGP P++ +GP + + T
Sbjct: 542 -PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD-LAGHSSSATST 599
Query: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS--- 526
P +L G P + PP + + P + G P + P P P P +
Sbjct: 600 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 659
Query: 527 ------TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
T ++ P SA P+ P K + G+G + P
Sbjct: 660 SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 709
Score = 80.5 bits (197), Expect = 4e-14
Identities = 135/617 (21%), Positives = 206/617 (33%), Gaps = 86/617 (13%)
Query: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
K + G+ P P +P+ PGS +PP P+A + A + KP
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPP----PVTPAALRVLGA--AGAVGRKP 57
Query: 558 VSQTGSG-----KPLQPPTVSPS-AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT-- 609
+++ G P P P+ +PP+ G + P NT+ + P +A+ T
Sbjct: 58 LAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 117
Query: 610 --------CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661
+ TV TE + L+ +R G P P +P P +
Sbjct: 118 GPLGQKGLRISAEETVA-------RGKATEAPKRSALSAGARRDTSG---PTPGTPSPAM 167
Query: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA-KA 720
+ V P P P++ +S A E P P PSA
Sbjct: 168 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP---SPAARRRPSAGGG 224
Query: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780
Q P + SLS A P + S P A P+ P P+ A P +
Sbjct: 225 LQRPASRSLSSSATP----LSSPARSGPSARGTPRAP--AHPSQPKPKGLQALRPPQV-- 276
Query: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840
+ + A P + A PS S PP+ +P + +P P + + P ++ S
Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPS--APPSLQTLPSPPA-----TPPSQATTS 329
Query: 841 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKP---MP--KGSPTPPGPRPTAGQTVPTPQ-- 893
G + +P P A P +P + P+PP P + P+PQ
Sbjct: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 389
Query: 894 --------QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASI--FSQAS 943
Q+P S P S TP L + AS
Sbjct: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449
Query: 944 NLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK 1001
+S + P P + AP Q P P PP PP QA P+P S P +
Sbjct: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL---QALPSPPASFPGQAPFS 506
Query: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPT----KLEKSPKPES 1057
A+ + P A P + PP+ + L P PT + +P P++
Sbjct: 507 PSASLPMSPLATPPP---------QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 557
Query: 1058 TCPLCKTELNIGSKDPP 1074
+ + L + PP
Sbjct: 558 SVSGPRLTLALAPGPPP 574
Score = 61.6 bits (148), Expect = 2e-08
Identities = 80/310 (25%), Positives = 117/310 (37%), Gaps = 49/310 (15%)
Query: 2377 PSGSPSVSSLPAKPR--PFFRSSSLDI-------SAQPPPPPPPPPPPPPPPPP------ 2421
PS PS+ +LP+ P P ++SL S P PP P PPP PP
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 2422 ---PPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI 2478
PP PP PP SP T P+ +P A L A + + +++ P
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQ------APNALAVHLLQAPFSPPPSPPVQAPFSP---- 415
Query: 2479 CTTAPPPVPPK---PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTG 2535
A PPV P PS P L P PP +P P+ P Q P + P
Sbjct: 416 --PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQ 472
Query: 2536 LSLTSSMT-LNLVTSADYKLPSP------TSPLSPHSN------KSSPRFSKSLTETYVV 2582
L+ L T LPSP +P SP ++ + P + + ++
Sbjct: 473 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 532
Query: 2583 ITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYIS 2642
PS P +PT + + T P S S +++ + PP P S+ ++
Sbjct: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL--ALAPGPPPPPSRSPSSTLSGPDLA 590
Query: 2643 GALQTFSATP 2652
G + ++TP
Sbjct: 591 GHSSSATSTP 600
Score = 59.3 bits (142), Expect = 1e-07
Identities = 85/361 (23%), Positives = 129/361 (35%), Gaps = 68/361 (18%)
Query: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP---PPPPPP 2424
G ++PAS+ S S + S PA+ P SA+ P P P P P PP
Sbjct: 224 GLQRPASRSLSSSATPLSSPARSGP---------SARGTPRAPAHPSQPKPKGLQALRPP 274
Query: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET------------TAVLRSNG 2472
PP P + P +A+P +A P A +L+T T L S
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334
Query: 2473 LPVTRICTTAPP--PVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIH 2530
L T +PP P+ P P L P PP +P P+ P + Q P
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP-PLSPLATPSPQAP---- 389
Query: 2531 PKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPG 2590
+++ ++L+ + PSP +P S +SP S S T P
Sbjct: 390 ---------NALAVHLLQAPFSPPPSPPVQ-APFSPPASPPVSPSAT--------PPSQA 431
Query: 2591 TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSA 2650
P+ ++ + P SP S P PP+ A + ++ A
Sbjct: 432 PPSLAAPPLQVPPSPPASPPMS-PSATPPPQAPPPLAAPPLQLAKPPP----------QA 480
Query: 2651 TPVTAPSSFQAAPTSVTQF-------LTTEVSKTEVSATRSTAPSVGLSSISITIPPEPL 2703
P A QA P+ F + + + ++ AP V L++ + +PP P
Sbjct: 481 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV-LAAPLLQVPPSPP 539
Query: 2704 A 2704
A
Sbjct: 540 A 540
Score = 55.1 bits (131), Expect = 2e-06
Identities = 89/425 (20%), Positives = 149/425 (35%), Gaps = 72/425 (16%)
Query: 685 KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744
K+D A ++ P + P L +P GSP +P PP P+
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPP--GSP--------------RPPPPVTPAALRVL 47
Query: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQ 804
A KP L + IP S ++ + PP S + +
Sbjct: 48 GAAGAVGRKP-----------LAERAGGIGGATIPESAPRAGPTRTSRPPA---SGRGER 93
Query: 805 SFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES----KGQKQVDPVQKKEEPKKAQT 860
+ P P S P AS + + PGP + ++ V + E PK++
Sbjct: 94 APPAKNTSPGPVSS---PGRASGT---TRPGPLGQKGLRISAEETVARGKATEAPKRSAL 147
Query: 861 KMSPKPDAKPMPKGSPTPPGPRPT--AGQTV----PTPQQSPKPQEQSRRFSLNLGSITD 914
+ D G+P+P R + AG V P P P+P + R S++ S
Sbjct: 148 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS 207
Query: 915 APKSQPTTPQETVTGKLFGFGAS-IFSQASNLISTAGQPGPHSQSGPGAPM--------- 964
+ P + G AS S ++ +S+ + GP ++ P AP
Sbjct: 208 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 267
Query: 965 ------------KQAPAPSQPPTSQGP-PKSTGQAPPAPAKSIPVKKETKAPAAEKLEPK 1011
++ AP+ P S P + APP+P+ ++ PA +
Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327
Query: 1012 AE-QAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS 1070
+PT++ T + PP+ + + A+ L+ P P ++ PL + L S
Sbjct: 328 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL--SPLATPS 385
Query: 1071 KDPPN 1075
PN
Sbjct: 386 PQAPN 390
Score = 53.5 bits (127), Expect = 5e-06
Identities = 79/328 (24%), Positives = 112/328 (34%), Gaps = 55/328 (16%)
Query: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP----PPPPPP 2424
Q KP P V+ P S A P P PP P PP P PP
Sbjct: 262 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT 321
Query: 2425 PP------------------LP-PPTSPKPTILPKKKLTVASPVTTATPLFDA---VTTL 2462
PP LP PP SP T P+ +A P A P A ++ L
Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 381
Query: 2463 ETTAVLRSNGLPVTRI-CTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL-- 2519
T + N L V + +PPP PP + P+ PP++P P
Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF---------SPPASPPVSPSATPPSQAP 432
Query: 2520 PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTET 2579
P+ P + P P +S ++ + + P P + K P+ +L T
Sbjct: 433 PSLAAPPLQVPPSP-----PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA-T 486
Query: 2580 YVVITLPSEPGT---PTDSSASQAITSWPLGSP--------SKDLVSVEPVFSVVPPVTA 2628
+ LPS P + S S ++ PL +P + L+ V P P + A
Sbjct: 487 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546
Query: 2629 VEIPISSEQTFYISGALQTFSATPVTAP 2656
P + +SG T + P P
Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPP 574
Score = 50.4 bits (119), Expect = 4e-05
Identities = 60/200 (30%), Positives = 74/200 (37%), Gaps = 47/200 (23%)
Query: 2335 LSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFF 2394
L + F PPS + P S S P SQ P PS+++ P + P
Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSAT------PPSQAP---PSLAAPPLQVPPSP 446
Query: 2395 RSSS-LDISAQPPPPPPPPPPPPP-----PPPPPPP----PPL-----PP---------- 2429
+S + SA PPP PPP PP PPP PP PPL PP
Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 506
Query: 2430 -----PTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE------TTAVLRSNGLPVTRI 2478
P SP T P+ +A+P+ P A TL+ T S P +
Sbjct: 507 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 566
Query: 2479 CTTAPPPVPP--KPSSIPSG 2496
PP PP PSS SG
Sbjct: 567 ALAPGPPPPPSRSPSSTLSG 586
Score = 44.3 bits (103), Expect = 0.003
Identities = 80/349 (22%), Positives = 115/349 (32%), Gaps = 54/349 (15%)
Query: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVA 2446
P P P S + P P P P PP P + + + T
Sbjct: 160 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS--------EHSTTEP 211
Query: 2447 SPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-----PPVPPKPSS-IPSGLVFT 2500
SP P + L S+ P++ + P P P PS P GL
Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 271
Query: 2501 HRPEPSKP---------PIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSAD 2551
P+ + P P++ P+ P+ P+ P L S + A
Sbjct: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS----APPSLQTLPSPPATPPSQAT 327
Query: 2552 YKLPSPTSPLSPHSNKSSPRFSKSLT---ETYVVITLP---SEPGTPTDSSASQAITSWP 2605
L SPT + HS SP S T + + LP + P P S T P
Sbjct: 328 TSLGSPTLQ-ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 386
Query: 2606 LGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVT-APSSFQAAPT 2664
+ + ++ FS PP V+ P S + +S SATP + AP S A P
Sbjct: 387 QAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASPPVSP-----SATPPSQAPPSLAAPP- 439
Query: 2665 SVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKP 2713
+V + +P + S+ P PLA + L KP
Sbjct: 440 ------------LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476
Score = 38.1 bits (87), Expect = 0.23
Identities = 84/363 (23%), Positives = 117/363 (32%), Gaps = 62/363 (17%)
Query: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTT 2461
+A+ P P PP P PPPP P + K A + AT A
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 2462 LETTAVLRSNGLPVTRICTTAPPP--VPPKPSSIPSGLVFTHRPEP-------------- 2505
T R++ P + APP P P S P T RP P
Sbjct: 78 GPT----RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 2506 --SKPPIAPK--PVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPL 2561
K APK + T PT P P + + + LP P
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSP------AMARRSRAAGTEVGLPRPAPSA 187
Query: 2562 SPHSNKSSPRFSKSLTETYVVITLPSEP---------GTPTDSSASQAITSWPLGSPSKD 2612
P PR S S + T PS G +S S + ++ PL SP++
Sbjct: 188 RPRPPTEGPRKSVSSASEHST-TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246
Query: 2613 LVSVE-----PVFSVVPP---VTAVEIPISSEQTFYISGALQTFSATPVTAPS------- 2657
S P P + A+ P + + AL S++P+ PS
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306
Query: 2658 -------SFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHL 2710
+ + P + TT + + AT S PS LS ++ P P AL L
Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366
Query: 2711 EKP 2713
+ P
Sbjct: 367 QAP 369
Score = 34.7 bits (78), Expect = 2.5
Identities = 38/141 (26%), Positives = 55/141 (39%), Gaps = 10/141 (7%)
Query: 3576 QSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKA 3635
Q+P A+ P P+P + + A +Q SPP SP V +P SP +
Sbjct: 367 QAPPSPPASPPLSPLATPSP----QAPNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPV 421
Query: 3636 LESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRA 3695
SA P + P P +P + P PPASP + P PL+ + ++
Sbjct: 422 SPSATPPSQAP-PSLAAPPLQVPPS----PPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476
Query: 3696 PFQYTEGYTTKGSQTMTSSGA 3716
P Q T Q + S A
Sbjct: 477 PPQAPPALATPPLQALPSPPA 497
Score = 33.5 bits (75), Expect = 5.6
Identities = 32/125 (25%), Positives = 46/125 (36%), Gaps = 3/125 (2%)
Query: 3573 SDTQSPQYLSATSPPKDKK-RPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLS 3631
S SP + SPP P+ + A +Q+ PSPP SP + S P
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461
Query: 3632 PGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691
L + + KP P +P + P + +P S S P+SP A
Sbjct: 462 APPPLAAPPLQLAKPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519
Query: 3692 SSRAP 3696
+AP
Sbjct: 520 PPQAP 524
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 123 bits (308), Expect = 5e-27
Identities = 279/1316 (21%), Positives = 463/1316 (35%), Gaps = 243/1316 (18%)
Query: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ--QP 425
P+ PAQ S + E P KA P VG Q G A PP ++ P+ ++ +
Sbjct: 216 PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEE 275
Query: 426 GLQSPAKAPGPTKTPVQQ-----------------PGPGKIPAQQAGPGKTSAQ-QTGPT 467
G +S +AP T++ V+ PG G PA G ++Q + G
Sbjct: 276 GSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKP 335
Query: 468 KPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527
+ S+ ++ PA Q ++ SQ ++ P + P +P PG T
Sbjct: 336 EEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGA-APAPPGKT 394
Query: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL--- 584
P + + K S ++ S + P SGK Q S AK+ P +G
Sbjct: 395 GPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 585 -PKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMK 643
P+ P ++ + E+ + ++ E + +L N +VK L + Q+K
Sbjct: 455 PPRKTGPAA--AQVQVGKQEEDSRSSSEESDSDREALAAMNA----AQVKP-LGKSPQVK 507
Query: 644 RALGGDLAPVP--SSPQPKLKTAPVTTTSAVSK----SSPQPQQTSPKKDA------APK 691
A + P+ + P P K P T ++ V K S +++S D AP
Sbjct: 508 PASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA 567
Query: 692 QDLS--------------KAPEPKKPPPLVK----------QPTLHGSPSAKAKQPPEAD 727
Q+ S K P K P V+ + + S SA +++ P A
Sbjct: 568 QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAM 627
Query: 728 SLSKPAP----------PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA----T 773
+ ++ P PK+ + + APV + P+ T SS A T
Sbjct: 628 TAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT-QAPRKAGTATSPAGSSPAVAGGT 686
Query: 774 TKP--DIPSSKVQSQAEEKTTPPLKTDSAKP--------SQSFPPTGE-----------K 812
+P D SS+ EEKT + AK + S P G K
Sbjct: 687 QRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGK 746
Query: 813 VSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872
P ++ DS+ S E+ P Q K KK Q K +P P
Sbjct: 747 TGPTVTQVKAEKQEDSESSEEESDSEEAAAS----PAQVKTSVKKTQAKANPAAARAPSA 802
Query: 873 KGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT------TPQET 926
KG+ + PG TA Q+SP + R N + P S P+ T +
Sbjct: 803 KGTISAPGKVVTAA--AQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQA 860
Query: 927 VTGKLFGFGASIF-SQASNLISTAGQPGP----HSQSGPGAPMKQAPAPSQPPTSQGPPK 981
TG G+S S + T Q P H AP K++P PT PP
Sbjct: 861 QTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT---PPG 917
Query: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----PPIKDSKSLT 1037
TG P+ + K++ ++E+ + E V + K P P +
Sbjct: 918 KTG-----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 972
Query: 1038 AEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPH 1097
A P +A + K+ EST +E + + T+C TP
Sbjct: 973 ATPAQAQAASTPRKARASESTARSSSSE-----SEDEDVIPATQCL-----------TP- 1015
Query: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLV 1157
G ++ MP A P+ +P +SS K + ++
Sbjct: 1016 -------------------GIRTNVVTMPTAH--PRIAPKASMAGASSSKES--SRISDG 1052
Query: 1158 KKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPE- 1216
KKQE T+ + + ++ P T+ Q + +KL K K +Q+ PE
Sbjct: 1053 KKQEGPA-TQVDSAVG-------TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPES 1104
Query: 1217 --------EKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQ 1268
+ EE+ + K PTP + L E +A E + D++
Sbjct: 1105 SDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEE--TAAESSEDDVVAPS 1162
Query: 1269 VQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAK 1328
+ + + P Q K K++ PS + +T K+ P AK
Sbjct: 1163 QSLLSGYMTPGLTPANSQASKATP-KLDSSPSVS----------STLAAKDDPDGKQEAK 1211
Query: 1329 PDQVEPG-KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGE--IPSLIPTDE 1385
P Q KT ++ S T+ + K +G + S+ + S++ + + P +E
Sbjct: 1212 PQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNE 1271
Query: 1386 KDILKGLKK--------------DSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEK 1431
+ + K D+ + S S KL + A+ K
Sbjct: 1272 AQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSG------DQPAARTPRSK 1325
Query: 1432 SEKKTQPHE-----VSPEQPKDQEKTQSLSETLEITISEEEIKES------QEERKDTFK 1480
+KK E VSPE+ K ++ + + E++ K S ++E ++ +
Sbjct: 1326 KKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQ 1385
Query: 1481 KD------SQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRR 1530
K Q P SK K+KS+ ++E +++S ++ Q+K++
Sbjct: 1386 KGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKK 1441
Score = 122 bits (307), Expect = 7e-27
Identities = 317/1444 (21%), Positives = 506/1444 (35%), Gaps = 222/1444 (15%)
Query: 46 SQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPS-MHRKQELDSSHPPKQSGRPPDPGR 104
S+ SEEE A L + A+ PS M K + ++ K P P
Sbjct: 85 SESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP-- 142
Query: 105 PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALS 164
+ +T L G+SP S + S + T + E + +P F +
Sbjct: 143 ------ATGKTVANL-----LSGKSPRK-SAEPSANTTLVSETEEEGSVPAF-----GAA 185
Query: 165 AVSSVVNKFNPFDLISDSEASQEETTKKQKV-VQKEQGKPEGIIKPPLQQQPPKPIPKQQ 223
A +V+ D+ +S +ET + K V+ Q K + + P P +
Sbjct: 186 AKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKV 245
Query: 224 GPGRDPLQQDGTPKSISSQQPEK-IKSQPPGTGKPIQGPTQTPQTDHA--KLPLQRDASR 280
G ++ P + +++PE+ +S G+ + P T A K+ R AS
Sbjct: 246 GDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASA 305
Query: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPA------ 333
P A G+ P+ P + Q GKP + E+S + PA
Sbjct: 306 P----AKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQ 361
Query: 334 --------QPSGLTKPLAQQPGTVKPPVQPPGTTKPP-AQPLGPAKPPAQQTGSEKPSSE 384
Q + P + P P PPG T P A+ + Q+ SE+ SE
Sbjct: 362 AKASGKTSQVGAASAPAKESPRKGAAPA-PPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420
Query: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ--------QPGLQSPAKAPGP 436
+ P A A+P G PAK ++ P P + Q G Q
Sbjct: 421 EEAP-AQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSS 479
Query: 437 TKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKP-PPQQPGPAKPPPQ-- 492
++ + + A Q P GK+ + T L A P PP + GPA P Q
Sbjct: 480 EESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVG 539
Query: 493 ---QPGSAKPPSQQPGSTKPPPQQPGPAKPSP-----QQPGSTKPPSQQPGSAKPSAQQP 544
+ + S P PA+ Q ++ P P A P A Q
Sbjct: 540 KWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQV 599
Query: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT-ICP-LCNTT------- 595
KP S + S + P +A+ P+ +P+T CP NTT
Sbjct: 600 KAEKP-MDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAP 658
Query: 596 -ELLLHVPEKANFNTCTECQTTVCSLCGFNPNP----------HLTEVKEWLCLNCQMKR 644
+ P KA T T + ++ G P E K L + +
Sbjct: 659 VRVGTQAPRKA--GTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAK 716
Query: 645 ALGGDL----APVP--------SSPQPKLKTAPVTTTSAVSK----SSPQPQQTSPKKDA 688
++G L A VP ++P KT P T K S + + S + A
Sbjct: 717 SVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAA 776
Query: 689 APKQDLS--KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK-EPSVPSEQD 745
+P Q + K + K P + P+ G+ SA K A + +P K +P V + Q+
Sbjct: 777 SPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN 836
Query: 746 KAPVADDKPKQPKMVKPTTDLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLKTDSAKPS 803
+A P + K + +++ A T P D SS+ +S +EE+ KPS
Sbjct: 837 STVLARGPASVPSVGKA---VATAAQAQTGPEEDSGSSEEESDSEEEAE---TLAQVKPS 890
Query: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK---KAQT 860
++P +K PR + GPS+ G KQ D EE +A
Sbjct: 891 GKTHQIRAALAP--AKESPRKGAAPTPPGKTGPSAAQAG-KQDDSGSSSEESDSDGEAPA 947
Query: 861 KMSPKPDAKPM-----PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA 915
++ KP P SP P P Q TP+++ + +R S
Sbjct: 948 AVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVI 1007
Query: 916 PKSQPTTP------------QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963
P +Q TP + K GAS ++S + Q GP +Q
Sbjct: 1008 PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVG 1067
Query: 964 MKQAPAP-SQPPTSQGPPK-------STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQ- 1014
A +P S ++G K QA AP S + + + + + + + Q
Sbjct: 1068 TLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1127
Query: 1015 --------APTVKRTETEKKPPPIKDSKSLTAEPQKAVL---------PTKLEKS---PK 1054
PT RTET + + S+ P +++L P + S PK
Sbjct: 1128 AKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPK 1187
Query: 1055 PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRA 1114
+S+ + T + +KD P+ E K Q + L + A
Sbjct: 1188 LDSSPSVSST---LAAKDDPDGK--QEAKPQ--------------QAAGMLSPKTGGKEA 1228
Query: 1115 ISGQLGDIRKMPPAPSG-PKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVIL 1173
SG + P +G P+AS + + + + P + E +V+ KV+
Sbjct: 1229 ASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPL-----NEAQVQASVVKVL- 1282
Query: 1174 EKVKETLSMEKIPPMVTTDQKQEES-KLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK 1232
E L E+ + TT + + + K K S Q P KK ++K+ + E
Sbjct: 1283 ---TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKK----KKKLGAGEG 1335
Query: 1233 KPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQ-EGKQP 1291
E +PE KTS + K K+ + E+K +G + + + E ++
Sbjct: 1336 ----GEASVSPE--------KTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEE 1383
Query: 1292 QTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351
K G G QS PK + K+ K + K + + K+K +K K S S
Sbjct: 1384 LQKGMGTVEGGDQSNPKSKKEKKKSDKRK-------KDKEKKEKKKKAKKASTKDSESPS 1436
Query: 1352 QQPK 1355
Q+ K
Sbjct: 1437 QKKK 1440
Score = 52.4 bits (124), Expect = 1e-05
Identities = 190/988 (19%), Positives = 330/988 (33%), Gaps = 152/988 (15%)
Query: 971 SQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA-------PAAEKLEPKAEQAPTVKRTET 1023
S P ++ + +A AK+ P T + P++ K + KAE K +
Sbjct: 79 SDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNS 138
Query: 1024 EKKPPPIKDSKSLTA--EPQKAVLP---TKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078
P K +L + P+K+ P T L + E + P G ++
Sbjct: 139 MPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADS 198
Query: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMP 1138
+E + + P + Q ++S + RK PAP
Sbjct: 199 SSEDTSSSSDETDVEGKPSVKPAQV-------KASSVSTKESPARKAAPAPG-------K 244
Query: 1139 VPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKV------KETLSMEKI------- 1185
V + K P K KK E+E ++ E E+ + + EKI
Sbjct: 245 VGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAAS 304
Query: 1186 -PPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP----LLEEKK 1240
P T + + K A A Q K PEE EE SEE+ P LL+ K
Sbjct: 305 APAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKA 364
Query: 1241 -----------------------PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE 1277
P P K AK A + ++ S+ +EE+
Sbjct: 365 SGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAP 424
Query: 1278 GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPD--QVEPG 1335
+ P GK PQ + P+ K + P PP P QV+ G
Sbjct: 425 AQAKPS----GKAPQVRAASAPA-----------KESPRKGAAPAPPRKTGPAAAQVQVG 469
Query: 1336 KEKTEKEDDKSDTSSSQQP-------------KSPQGLSDTGYSSDGISSSLGEIP--SL 1380
K++ + ++ S ++ KSPQ + + G +P +
Sbjct: 470 KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKV 529
Query: 1381 IPTDEKDILKGLKKDS--FSQESSPSSPSDLAKL-----ESTVLSILEAQASTLADEKSE 1433
P + ++DS S+ESS SS ++ E ++ +IL+A+ ++ +
Sbjct: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPP 589
Query: 1434 KKTQPHEVSPEQPKDQEKTQSLSETLEITISEEE-IKESQEERKDTFKKDSQQDIPSSKD 1492
+K P V + K + ++S E+ + SEE + + K K + P +
Sbjct: 590 QKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
Query: 1493 HKEKSEFVDDITTRREPYDSVEESSESENSP-VPQRKRRTSVGSSSSDEYKQEDSQGSGE 1551
++ + P + +S + +SP V +R + SSSS+E S
Sbjct: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEE--------SDS 701
Query: 1552 EEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL 1611
EE+ + A G + + +++ K +G + GK
Sbjct: 702 EEEKTGLAVTVGQAKSVGKGLQ-----------VKAASVPVKGSLGQGTAPVLPGKTGPT 750
Query: 1612 TRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIE 1671
+ ED+ S + D E SP K +++ R + +
Sbjct: 751 VTQVKAEKQEDS--ESSEEESDSEEAAASPAQVKTSVKKTQAK-----ANPAAARAPSAK 803
Query: 1672 LNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSP 1731
+ K ++Q K P + + G +S+ + T+
Sbjct: 804 GTISAPGKVVTAAAQAK-----QRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAA 858
Query: 1732 TSVSSLDEDSDSSPSHKKGESKQQRKARHRPHG-------PLLPTIEDSSEEEELREEEE 1784
+ + +EDS SS E + + A+ +P G L P E S +
Sbjct: 859 QAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKE--SPRKGAAPTPP 916
Query: 1785 LLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP----PSNLSPIEDASPTE 1840
+ +Q SSS++S D + A + K P N SP A+
Sbjct: 917 GKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPA 976
Query: 1841 ELRQAAEMEELHRSSCSEYSPSIESDPE 1868
+ + A+ + S + S S ES+ E
Sbjct: 977 QAQAASTPRKARASESTARSSSSESEDE 1004
Score = 52.0 bits (123), Expect = 2e-05
Identities = 119/646 (18%), Positives = 233/646 (36%), Gaps = 77/646 (11%)
Query: 1299 PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKP----DQVEPGKEKTEKEDDKSDTSSSQQP 1354
P T +S +E++ +T K P+ T D KEK + E +K+ + + P
Sbjct: 81 PISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMP 140
Query: 1355 --------------KSPQGLSDTGYSSDGISSSL--GEIPSLIPTDEKDILKGLKKDSFS 1398
KSP+ ++ ++ +S + G +P+ + ++ + DS S
Sbjct: 141 HPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSS 200
Query: 1399 QESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSET 1458
+++S SS + + +V +S E +K P Q K +L
Sbjct: 201 EDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPA 260
Query: 1459 LEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSE 1518
EEE + S+E +S+++ P+ + K+ + I R + +
Sbjct: 261 KRAKKPEEESESSEE------GSESEEEAPAGTRSQVKAS--EKILQVRAASAPAKGTPG 312
Query: 1519 SENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFI 1578
+P P K +V S + +EDS+ S EE ++ A A S
Sbjct: 313 KGATPAPPGK-AGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKAS------ 365
Query: 1579 RNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFD 1638
+ ++ +++ K+ KG GK K+ AG+R +ED ++
Sbjct: 366 -GKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKA------QAGKR----EEDSQSSS 414
Query: 1639 ESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIAD-KYSAESSQKKT--SLYFDE 1695
E E+ S+E G + + + + K +A + +KT + +
Sbjct: 415 E-------ESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ 467
Query: 1696 EPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQ 1755
+ E +S + S E S E ++++A+ P L + P+ G
Sbjct: 468 VGKQEEDSRSSSEESDSDREALAAMNAAQVKP---------LGKSPQVKPASTMGMGPLG 518
Query: 1756 RKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELR 1815
+ A P G + P S++ + E+ E E+ + + + K + L+
Sbjct: 519 KGAGPVPPGKVGPA-TPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ 577
Query: 1816 AQRRRERPKTPPSNLSPI----------EDASPTEELRQAAEMEELHRSSCSEYSPSIES 1865
A+ K PP P+ +++ +EE +A+ EE + + +
Sbjct: 578 AKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALK 637
Query: 1866 DPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKAL 1911
P+ + P+K P V +P + GS A+
Sbjct: 638 IPQ-TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAV 682
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 123 bits (308), Expect = 5e-27
Identities = 160/632 (25%), Positives = 208/632 (32%), Gaps = 147/632 (23%)
Query: 209 PPLQQQPPKPIPKQQGPG-----------------RDPLQQDGT---PKSISSQQPEKIK 248
PP PP P+P Q P ++ Q G P + Q + +K
Sbjct: 639 PPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVK 698
Query: 249 SQ---PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP 305
Q PP P P P T + + Q K A PSLP S PP
Sbjct: 699 PQILVPPNGVVPPPPPPPPPPTPGSAMA--------QLKPAPCA------PSLPQFSAPP 744
Query: 306 ----------IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL--------TKPLAQ--- 344
I Q P PP P P P P A P L TK +A
Sbjct: 745 PPLKIHQVQHITQVAPPTPPPPPP-----IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVT 799
Query: 345 --QPGTVKPPVQP-------PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
P T PPV P P + PP+ P P P ++ +P P L+ P
Sbjct: 800 QAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVP 859
Query: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAG 455
V K A Q P PPT +PL P +P P P QP +P+
Sbjct: 860 SVVKQIASQFPP--PPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP 917
Query: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP---- 511
P + P PPS +P P PPP P PG + PG KPPP
Sbjct: 918 PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQR 977
Query: 512 ----------QQPGPAKPSPQQPGSTKPPSQQPGSAK-----PSAQQPSPAK-------- 548
+ P P +PS S P + GS P A P P K
Sbjct: 978 NSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNL 1037
Query: 549 PSAQQ----STKPVSQTGSGKPL-----QPPTVSPSAKQPPSQGLPKTICPLCNTTELLL 599
P Q S K +G GK PP+ S PP LP + P +
Sbjct: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP--LPP--------I 1087
Query: 600 HVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQP 659
+P + NT + NP P ++W ++ + AP P+ P+
Sbjct: 1088 EIPAVFSGNTSPKVAVV-------NPQP-----QQWSKMSVKK--------APPPTRPK- 1126
Query: 660 KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP---EPKKPPPLVKQPTLHGSP 716
+ T A P P+ +PK LS P K T HGS
Sbjct: 1127 --RNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSL 1184
Query: 717 SAK-AKQPPEADSLSKPAPPKEPSVPSEQDKA 747
S++ ++ P A PP P + S+Q KA
Sbjct: 1185 SSRMSRAEPTATMDDMALPPPPPELLSDQQKA 1216
Score = 116 bits (291), Expect = 5e-25
Identities = 166/650 (25%), Positives = 238/650 (36%), Gaps = 77/650 (11%)
Query: 266 QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPS-KPPIQQPTPGKPPAQQPGHEKS 324
Q++H+ Q D+ T+ A VR +S+ S+ S + K Q K + +
Sbjct: 547 QSNHSN---QSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYT 603
Query: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384
P P QP +T A QP PP PP PP P P P+Q PS+
Sbjct: 604 SLVPPLSP-QPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSA----PSAG 658
Query: 385 QPGPKALAQPPGVGKTPAQQPGPA--KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
P + A Q A KPPT V + + Q L P P P
Sbjct: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQI-LVPPNGVVPPPPPPPP 717
Query: 443 QPGPGKIPAQ-QAGPGKTSAQQTGPTKPPSQL--------PGPAKPPPQQPGPAKPPPQQ 493
P PG AQ + P S Q PP ++ P PPP P PA PPQ
Sbjct: 718 PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA 777
Query: 494 PGSAKPPSQQPGSTK---PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550
P P STK P Q P P+P P + K P+ PS P+P P
Sbjct: 778 PPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS--PPTPPVP- 834
Query: 551 AQQSTKPVSQTGSGKPLQPP-TVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT 609
T P Q+ KP P + PS + + P P ++ L VP N
Sbjct: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPA----NV 890
Query: 610 CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA---PV 666
+ V + + P+ P P P P +++ P
Sbjct: 891 APQSPPAVKAKPKWQPS---------------------SIPVPSPDFPPPPPESSLVFPP 929
Query: 667 TTTSAVSKSSPQPQQT---SPKKDAAPKQDLSKAPEP--KKPPPL-VKQPTLHGSPSAKA 720
S V P P T +P K +P + SK P KKPPP + ++ S A+
Sbjct: 930 PPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEH 989
Query: 721 KQP--PEADSL-SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDL---VSSSSATT 774
+P P DSL SK PP E PS++ P A PK K+ +L + +
Sbjct: 990 PEPKRPSVDSLVSKFTPPAESGSPSKETLPPPA-APPKPGKLNLSGVNLPGVLQQGCVSA 1048
Query: 775 KPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI-ISH 833
K + S + + E +PP +D P P T + P + A+ + K+ + +
Sbjct: 1049 KAPVLSGRGKDSVVEFPSPPSDSDFPPPP---PETELPLPPIEIPAVFSGNTSPKVAVVN 1105
Query: 834 PGPSSESKGQKQVDP----VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879
P P SK + P ++ + + Q ++S +P + PT P
Sbjct: 1106 PQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155
Score = 98.2 bits (243), Expect = 2e-19
Identities = 167/666 (25%), Positives = 217/666 (32%), Gaps = 151/666 (22%)
Query: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP------QQPGSAKP-------------P 500
+A Q P PP P P PPP P P PPP GSA P
Sbjct: 620 TASQPSPPLPP---PPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNA 676
Query: 501 SQQPGSTKPPPQQPGPAKPS--PQ---------QPGSTKPPSQQPGSAKPSAQQPSPAKP 549
SQ G+ PP P S PQ P PP PGSA + +P+P P
Sbjct: 677 SQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAM-AQLKPAPCAP 735
Query: 550 SAQQSTKP-----VSQTGSGKPLQPPTVSPSAKQP---PSQGLPKTICPLCNTTELLLHV 601
S Q + P + Q + PPT P P P Q PK L+ +
Sbjct: 736 SLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKP----------LVTI 785
Query: 602 PEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661
P + T P +T+ P P+ P P
Sbjct: 786 PAPTSTKTVA---------------PVVTQA-----------------APPTPTPPVPPA 813
Query: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721
K P S + S P P P PKQ A KPPP SP +
Sbjct: 814 KKQPAFPASYIPPSPPTPPVPVP-PPTLPKQQSFCA----KPPP---------SPLSPVP 859
Query: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIP-- 779
+ + P PP P++ S+ K A+ P+ P VK SS PD P
Sbjct: 860 SVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPP 919
Query: 780 ---SSKV-----QSQAEEKTTPPLKTDSAKPSQSFPP---TGEKVSPFDSKAIPRPASDS 828
SS V S PP T S P +S P T + SP K P P +S
Sbjct: 920 PPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNS 979
Query: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT 888
I S G + VD + K P SP + P P +P PG +G
Sbjct: 980 SIKSSSGAEHPEPKRPSVDSLVSKFTPPAESG--SPSKETLP-PPAAPPKPGKLNLSGVN 1036
Query: 889 VPTPQQ----SPKPQEQSRRFSLNLGSITDAPKSQ--PTTPQETVTGKLFGFGASIFSQA 942
+P Q S K S R ++ P P P ET ++FS
Sbjct: 1037 LPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFS-- 1094
Query: 943 SNLISTAGQPGPHSQSGPGAPMKQAPAPSQP-----------PTSQGPPKST--GQAPPA 989
N P Q +K+AP P++P S+ P +T Q P +
Sbjct: 1095 GNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154
Query: 990 PAKSIPVKKETKAPAAEKLEPK------------AEQAPTVKRTETEKKPPPIKDSKSLT 1037
P S+ V+ A L+ K + PT + PPP L
Sbjct: 1155 PKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPP----PELL 1210
Query: 1038 AEPQKA 1043
++ QKA
Sbjct: 1211 SDQQKA 1216
Score = 92.4 bits (228), Expect = 1e-17
Identities = 88/292 (30%), Positives = 125/292 (42%), Gaps = 43/292 (14%)
Query: 2369 QEKPASQLPSGSPSVSSL--PAKPRPFFRSSSLDISAQPP-PPPPPPPPPPPPPPPPPPP 2425
+E +++ S + +SL P P+P + PP PPPPPPPPPPPPPPPPPPP
Sbjct: 588 EESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP 647
Query: 2426 PLPPPTSPKP-TILPK-KKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT--- 2480
PLP ++P + P K + + + A+ A+ T V++S + +
Sbjct: 648 PLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNG 707
Query: 2481 TAPPPVPPKPSSIPSGLVFTHRPEP--------SKPP-------------IAPKPVIPQL 2519
PPP PP P P + +P P S PP +AP P
Sbjct: 708 VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP 767
Query: 2520 PTTTQKPTDIHPKP--TGLSLTSSMTL-NLVTSADYKLPSPTSPLSPHSNKSSPRFSKSL 2576
P P PKP T + TS+ T+ +VT A P+PT P+ P K P F S
Sbjct: 768 PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQA--APPTPTPPVPP--AKKQPAFPAS- 822
Query: 2577 TETYVVITLPSE--PGTPTDSSASQAITSWPLGSPSKDLVS-VEPVFSVVPP 2625
Y+ + P+ P P Q+ + P SP + S V+ + S PP
Sbjct: 823 ---YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPP 871
Score = 87.4 bits (215), Expect = 3e-16
Identities = 150/606 (24%), Positives = 214/606 (35%), Gaps = 124/606 (20%)
Query: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728
TS V SPQP+ +P + P L P P PPP P PS A P A S
Sbjct: 603 TSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSA---PSAGS 659
Query: 729 LSKPAPPKEPSVPSEQDKA------------PVADDKPKQPKMVKPTTDLVSSSSATTKP 776
+ P K ++ Q+ + PV + +P+++ P +V P
Sbjct: 660 -AAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPP 718
Query: 777 DIPSSKVQSQAEEKTTPPLKTDSAKP-----------SQSFPPTGEKVSPFDSKAIPRPA 825
P S + P L SA P +Q PPT P + +P A
Sbjct: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPA-PLPPQA 777
Query: 826 SDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP--KGSPTPPGPRP 883
+++ P P+S K V PV + P T P P AK P S PP P P
Sbjct: 778 PPKPLVTIPAPTS----TKTVAPVVTQAAP---PTPTPPVPPAKKQPAFPASYIPPSP-P 829
Query: 884 TAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQAS 943
T VP P PK Q S P P +P +V ++ AS F
Sbjct: 830 TPPVPVP-PPTLPKQQ-----------SFCAKPPPSPLSPVPSVVKQI----ASQFPPPP 873
Query: 944 NLISTAGQP------GPHSQSGPGAPMK--------QAPAPSQPPTSQGPPKSTGQAPPA 989
+ QP QS P K P+P PP PP+S+ PP
Sbjct: 874 TPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPP---PPESSLVFPPP 930
Query: 990 PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE----KKPPP-------IKDSKSLT- 1037
P +P P A P +P K ++T KKPPP IK S
Sbjct: 931 PPSPVPAPPPPPPPTASP-TPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEH 989
Query: 1038 AEPQKAVLPTKLEK-SPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTP 1096
EP++ + + + K +P ES P +T PP K NL G N
Sbjct: 990 PEPKRPSVDSLVSKFTPPAESGSPSKET------LPPP----AAPPKPGKLNLSGVN--- 1036
Query: 1097 HLTEIQEWLCLNCQTQRAISGQLGD-IRKMPPAPSGPKASPMPVPTESSSQKTAVP---- 1151
L + + C++ + +SG+ D + + P PS P P TE +P
Sbjct: 1037 -LPGVLQQGCVSAKAP-VLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFS 1094
Query: 1152 ----PQVKLVKKQEQE---------------VKTEAEKVILEKVKETLSMEKIPPMVTTD 1192
P+V +V Q Q+ + ++ ++ ++ E +M + P V T
Sbjct: 1095 GNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154
Query: 1193 QKQEES 1198
K S
Sbjct: 1155 PKSSLS 1160
Score = 72.0 bits (175), Expect = 1e-11
Identities = 101/398 (25%), Positives = 144/398 (36%), Gaps = 83/398 (20%)
Query: 2343 PPSSVIALPMKEQLSTTYFTSGET--FGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
PPS + +P + + F T + +P +P+ S K +P ++ SS+
Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910
Query: 2401 ISAQPPPPPPPP-----PPPPPPPPPPPPPPLPPPTSPKP--TILPKKKLTVASPVTTAT 2453
+ + PPPPP PPPPP P P PPPP PP SP P + P KK + T++
Sbjct: 911 VPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTS-----KTSS 965
Query: 2454 PLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPK 2513
P PPP P + SSI S H PEP +P +
Sbjct: 966 P------------------------GGKKPPPTPQRNSSIKSSSGAEH-PEPKRPSVD-- 998
Query: 2514 PVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYK--LPSPTSPLSPHS-NKSSP 2570
SL S T + + K LP P +P P N S
Sbjct: 999 -----------------------SLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGV 1035
Query: 2571 RFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVE 2630
L + V P G DS + +P SP D P P+ +E
Sbjct: 1036 NLPGVLQQGCVSAKAPVLSGRGKDS-----VVEFP--SPPSDSDFPPPPPETELPLPPIE 1088
Query: 2631 IPI-----SSEQTFYISGALQTFSATPV-TAPSSFQAAPTSVTQFLTTEVSKTEVSATRS 2684
IP +S + ++ Q +S V AP + T+ E+S+ AT
Sbjct: 1089 IPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMAT-- 1146
Query: 2685 TAPSVGLS-SISITIPPEPLALDNIHLEKPQYKEDGKL 2721
P V S S+++ P LA N L++ G L
Sbjct: 1147 VVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSL 1184
Score = 37.4 bits (85), Expect = 0.39
Identities = 66/285 (23%), Positives = 97/285 (34%), Gaps = 54/285 (18%)
Query: 66 LPKGSVPPAAAESPSMHRK---QELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSE 122
+P PP ES + + + PP P P + PG S+T+
Sbjct: 911 VPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSP---- 966
Query: 123 QKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDS 182
G+ P + S ++ EH P +V S+V+KF P
Sbjct: 967 ---GGKKPPPTPQRNSSIKSSSGAEHPEPKRP----------SVDSLVSKFTP----PAE 1009
Query: 183 EASQEETTKKQKVVQKEQGK--PEGIIKPPLQQQ--PPKPIPKQQGPGRDPLQQDGTPKS 238
S + T + GK G+ P + QQ P G G+D + + +P S
Sbjct: 1010 SGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPS 1069
Query: 239 ISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSL 298
S P PP T P+ P + P + PQ +Q + SVK +
Sbjct: 1070 DSDFPP-----PPPETELPLP-PIEIPAVFSGNTSPKVAVVNPQPQQWSKM---SVKKA- 1119
Query: 299 PSPSKPP------------IQQPTPGKPPAQQPGHEKS----QPG 327
P P++P +QPT Q P KS QPG
Sbjct: 1120 PPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPG 1164
Score = 32.7 bits (73), Expect = 9.6
Identities = 31/123 (25%), Positives = 46/123 (37%), Gaps = 14/123 (11%)
Query: 3614 PSPPKSPKVLYSPISPLSPGKALESAFVPYEKPL--PDDISPQKVLHPDMAKVPPASPKT 3671
P PP P + P+ P+ A +S KP P I V PD PP P++
Sbjct: 870 PPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP---VPSPDF---PPPPPES 923
Query: 3672 AKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEE 3731
+ + P P P + +P G K + +S G +K P P P+
Sbjct: 924 SLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKK------PPPTPQR 977
Query: 3732 IST 3734
S+
Sbjct: 978 NSS 980
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 122 bits (306), Expect = 9e-27
Identities = 310/1401 (22%), Positives = 555/1401 (39%), Gaps = 169/1401 (12%)
Query: 1088 NLCGFNPTPHLTEIQEWLCLNCQTQRAISGQ-LGDIRKMPPAPSGPKASPMPVPTESSSQ 1146
+L G PTP + + + QRA S + L K P+ S K S P +
Sbjct: 520 DLTGQVPTPVVKQTK-------LKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVN 572
Query: 1147 KTAVPPQV----KLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEK 1202
PP+V K++ K+++ +KTE + + EK E S E+ P V + ++++ K
Sbjct: 573 HVEKPPKVESKEKVMVKKDKPIKTETKPSVTEK--EVPSKEE-PSPVKAEVAEKQATDVK 629
Query: 1203 DKAS----ALQEKKPLPEEKKLI---PEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTS 1255
KA+ +E K PE+KK P++E + E+K P+ +E+KP E+ K E K
Sbjct: 630 PKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVK--KEVKKE 687
Query: 1256 APEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK 1315
+E+K + K ++ +E V + +E K+ K E P + LPK+ K++
Sbjct: 688 IKKEEKKEPKK---EVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSST 744
Query: 1316 TIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLG 1375
+ E +P KP P KE++ K+D + ++ K + + G +++ +++++G
Sbjct: 745 PLSEAKKP-AALKPKV--PKKEESVKKDSVAAGKPKEKGKI-KVIKKEGKAAEAVAAAVG 800
Query: 1376 E--IPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAK-------LESTVLSILEAQAST 1426
+ + G K+ ++ S SSP DL K E V ++ Q
Sbjct: 801 TGATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLEL 860
Query: 1427 LADEKSEKKTQPHE---VSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDS 1483
+ DE+ K+T+P E + E+ + +S E + T E E +++ EE + +K
Sbjct: 861 IEDEEKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPV-EKQG 919
Query: 1484 QQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQ 1543
DI +D E + F + T EE +E+E + P+ V S+S
Sbjct: 920 VDDIEKFED--EGAGFEESSET-----GDYEEKAETEEAEEPEEDGEEHVCVSASKHSPT 972
Query: 1544 EDSQGSGEEED-FIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGK 1602
ED + + E D +IR++ +++ +D + + DE I E S ++ + + +
Sbjct: 973 EDEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREE 1032
Query: 1603 ITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKY------RETKSQESEEL 1656
+ +D+ A + E+ F +P + RE S +E
Sbjct: 1033 EYEPEKMEAEDYVMAVVDKAA---EAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDET 1089
Query: 1657 VVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPEL--EMESLTDSPEDRSRG 1714
+ G E ++++A S ++++ EP EM + D D +
Sbjct: 1090 LPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRDVMSDETNN 1149
Query: 1715 EG--SSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIED 1772
E S S + T S + +D +P + E + + + TI
Sbjct: 1150 EETESPSQEFVNITKYESSLYSQEYSKPADVTPLNGFSEGSKTDATDGKDYNASASTISP 1209
Query: 1773 SSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP---PSN 1829
S EE + L R+ + K+S+ KD + + K+P PS
Sbjct: 1210 PSSMEEDKFSRSAL------RDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSLSPSP 1263
Query: 1830 LSPIEDASPTEE-LRQAAEMEELHRSSCSEYSP-SIESDPEGFE---ISPE-KIIEVQKV 1883
SP+E E + + E+ S+ +E +P S E E E SPE K +EV
Sbjct: 1264 PSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPEDKTLEVVSP 1323
Query: 1884 YKLPTAVSLY-----SPTDEQS------IMQKEGSQKALKSAEEMYEEMMHKTHKYKAFP 1932
+ T + + SPTDE+S +++K + + +E + P
Sbjct: 1324 SQSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKPPAVPVSFEFSDAKDENERASVSPMDEP 1383
Query: 1933 AANERDEVFEK--EPLYGGMLI-EDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQKGR 1989
+ + EK PL LI + YES + S G+ E+ F ++ G+
Sbjct: 1384 VPDSESPI-EKVLSPLRSPPLIGSESAYESFLSADDKASGRGA-------ESPFEEKSGK 1435
Query: 1990 EQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESHEIVDLGTMV 2049
+ +Q+ T L ++ E +S +ED ++ ++ + +
Sbjct: 1436 QGS---PDQVSPVSEMTSTSLYQDKQEGKSTDFAPIKEDFGQEK----KTDDVEAMSSQP 1488
Query: 2050 TSTEEERKLLDAD------AAYEELMKRQQMQLTPG--SSPTQAPIGEDMTESTMDFDRM 2101
+ERKL D + + + +M ++ G S + P+ E + E T
Sbjct: 1489 ALALDERKLGDVSPTQIDVSQFGSFKEDTKMSISEGTVSDKSATPVDEGVAEDTY----- 1543
Query: 2102 PDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHES 2161
S + G + + S AT S P+ T + + E + ++ E+ + ++ S
Sbjct: 1544 -------SHMEGVASVSTASVATSSFPEP--TTDDVSPSLHAEVGSPHSTEVDDSLS-VS 1593
Query: 2162 LILTYSEPSESATSVPPSDTP---SLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMIT 2218
++ T + E+ S + P S++ S T S +P+ S E M
Sbjct: 1594 VVQTPTTFQETEMSPSKEECPRPMSISPPDFSPKTAKSRTPVQDHRS------EQSSMSI 1647
Query: 2219 KF-EDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESV 2277
+F ++S E S + F D+P + L T +G D+ S SDM S +
Sbjct: 1648 EFGQESPEQSLAMDFSRQSPDHPTVGAGVLHITE--NGPTEVDY---SPSDMQDSSLSHK 1702
Query: 2278 VPKPEGPVADTVSTDL--LIS----EKDPVKKAKKETGNGIILEVLEAY-------RDKK 2324
+P E P + T DL LIS E P + T + I + E RD
Sbjct: 1703 IPPMEEP-SYTQDNDLSELISVSQVEASP-STSSAHTPSQIASPLQEDTLSDVAPPRDMS 1760
Query: 2325 ---ELEAERTKSSLSETVFDHPPSSVIALPMKEQ--LSTTYFTSGETFGQEKPASQLPSG 2379
L +E+ +S E + P S + L +E L + F+ + +EK A+ S
Sbjct: 1761 LYASLTSEKVQSLEGEKL--SPKSDISPLTPRESSPLYSPTFSDSTSAVKEKTATCHSSS 1818
Query: 2380 SPSVSSLPAKPRPFFRSSSLD 2400
SP + + A+P F S D
Sbjct: 1819 SPPIDAASAEPYGFRASVLFD 1839
Score = 102 bits (254), Expect = 1e-20
Identities = 265/1334 (19%), Positives = 482/1334 (36%), Gaps = 191/1334 (14%)
Query: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711
P P Q KLK + S + P P + + K+ + PE K + K P
Sbjct: 526 PTPVVKQTKLKQRADSRESLKPAAKPLPSK------SVRKESKEETPEVTKVNHVEKPPK 579
Query: 712 LHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPV-ADDKPKQPKMVKPTTDLVSSS 770
+ K+ + +KP+ E VPS+++ +PV A+ KQ VKP +
Sbjct: 580 VESKEKVMVKKDKPIKTETKPS-VTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTV 638
Query: 771 SATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR--PASDS 828
TK P K + + + K K D + P E+V K I +
Sbjct: 639 KKETKVK-PEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPK 697
Query: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT 888
K + P E K K+V +KKE K+ + PK + K +PK + P A +
Sbjct: 698 KEVKKETPPKEVK--KEVKKEEKKEVKKE---EKEPKKEIKKLPKDAKKSSTPLSEAKKP 752
Query: 889 VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST 948
+ PK +E ++ S+ G PK + GK A+ + +
Sbjct: 753 AALKPKVPKKEESVKKDSVAAGK----PKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAV 808
Query: 949 AGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL 1008
G + GP ++ ++ P T A+ + V K+ K P E +
Sbjct: 809 MAAAG-IAAIGPAKELE-----AERSLMSSPEDLTKDFEELKAEEVDVTKDIK-PQLELI 861
Query: 1009 EPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNI 1068
E + + +K TE + I+ + +T P ++ P + + + E C EL
Sbjct: 862 EDEEK----LKETE-PVEAYVIQKEREVTKGPAES--PDEGITTTEGEGECEQTPEEL-- 912
Query: 1069 GSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPA 1128
+P + + GF + + +E +T+ A
Sbjct: 913 ---EPVEKQGVDDIEKFEDEGAGFEESSETGDYEE----KAETEEA-------------- 951
Query: 1129 PSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS------- 1181
P E + V + E+ K EA+ I EK + S
Sbjct: 952 ---------EEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEE 1002
Query: 1182 -MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKK--------LIPEEEKIRSEEK 1232
M++ +Q +EE+ E+DKA +E++ PE+ + + E +EE+
Sbjct: 1003 DMDEAIEKGEAEQSEEEAD-EEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQ 1061
Query: 1233 KPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLL-----KSQVQIA-EEKLEGRVAPKTVQ 1286
L T K+L ++ P HD +S+ + EE E + T
Sbjct: 1062 YGFL-----TTPTKQLGAQSPGREPASSIHDETLPGGSESEATASDEENREDQPEEFTAT 1116
Query: 1287 EG-KQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCT-----------------AK 1328
G Q ++ P+ + D + +T E+ + P +K
Sbjct: 1117 SGYTQSTIEISSEPTPMDEMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSK 1176
Query: 1329 PDQVEP-----GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSS-LGEIPSLIP 1382
P V P KT+ D K +S+ P + + +S + + E+ +
Sbjct: 1177 PADVTPLNGFSEGSKTDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTT 1236
Query: 1383 TDEKDILKGLKKDSFSQESSPS-SPSDLAKLESTVLS---------------ILEAQAST 1426
D KD + + + S SPS SPS + LE T L EA+ +
Sbjct: 1237 LDIKDSISAVSSEKVSPSKSPSLSPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAP 1296
Query: 1427 LADEKSEKKTQPHEVSPEQPKDQ--EKTQSLSETLEITISEEEIKESQEERKDTFKKDSQ 1484
++ E +++ + H SPE + +QS++ + T + + + T +
Sbjct: 1297 VSPEVTQEVVEEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKP 1356
Query: 1485 QDIPSS---KDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSS-DE 1540
+P S D K+++E ++ EP E E SP+ + +GS S+ +
Sbjct: 1357 PAVPVSFEFSDAKDENERA-SVSPMDEPVPDSESPIEKVLSPL---RSPPLIGSESAYES 1412
Query: 1541 YKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGK 1600
+ D + SG + S E+ SG + + + E++S++ Q K+E
Sbjct: 1413 FLSADDKASGRGAE---------SPFEEKSGKQGSPDQVSPVSEMTSTSLYQDKQE---- 1459
Query: 1601 GKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETK--SQESEELVV 1658
GK T I ED G+ +D EA P L E K ++ V
Sbjct: 1460 GKST----------DFAPIKEDFGQEKK--TDDVEAMSSQPALALDERKLGDVSPTQIDV 1507
Query: 1659 TGGGGLRRFKTIELN-STIADKYSA---ESSQKKTSLYFDEEPELEMESL-TDSPEDRSR 1713
+ G + + ++ T++DK + E + T + + + S+ T S + +
Sbjct: 1508 SQFGSFKEDTKMSISEGTVSDKSATPVDEGVAEDTYSHMEGVASVSTASVATSSFPEPTT 1567
Query: 1714 GEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDS 1773
+ S SLHA +P ++ S + + ++ E ++ RP P
Sbjct: 1568 DDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDFSPK 1627
Query: 1774 SEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPP--SNLS 1831
+ + ++ ++ E Q+ + S L R+ P P + +
Sbjct: 1628 TAKSRTPVQDHRSEQSSMSIEFGQESPEQS----------LAMDFSRQSPDHPTVGAGVL 1677
Query: 1832 PIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVS 1891
I + PTE ++M++ SS S P +E + ++I V +V P+ S
Sbjct: 1678 HITENGPTEVDYSPSDMQD---SSLSHKIPPMEEPSYTQDNDLSELISVSQVEASPSTSS 1734
Query: 1892 LYSPTDEQSIMQKE 1905
++P+ S +Q++
Sbjct: 1735 AHTPSQIASPLQED 1748
Score = 70.5 bits (171), Expect = 4e-11
Identities = 348/1859 (18%), Positives = 658/1859 (35%), Gaps = 316/1859 (16%)
Query: 245 EKIK-----SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSL- 298
EK+K QP T K + G TP KL + D+ ES+KP+
Sbjct: 503 EKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSR------------ESLKPAAK 550
Query: 299 PSPSKPPIQQPTPGKPPAQQPGHEKSQPG-------------PAKPPAQPSGLTK--PLA 343
P PSK ++ P + H + P P K +PS K P
Sbjct: 551 PLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSK 610
Query: 344 QQPGTVKPPVQPPGTT--KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP 401
++P VK V T KP A K + +K ++ K +A+ KTP
Sbjct: 611 EEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKED--KTP 668
Query: 402 AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461
++ KP ++V K ++ + K P P K ++ +
Sbjct: 669 IKKE--EKPKKEEV---KKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKK 723
Query: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS- 520
++ P K +LP AK AK +P + KP K P ++ K S
Sbjct: 724 EEKEPKKEIKKLPKDAKKSSTPLSEAK----KPAALKP--------KVPKKEESVKKDSV 771
Query: 521 ----PQQPGSTKPPSQQPGSAKP-SAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPS 575
P++ G K ++ +A+ +A + A +A + ++ G K L+ S
Sbjct: 772 AAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMS 831
Query: 576 AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEW 635
+ + ++ + + T+ P L E +E
Sbjct: 832 SPEDLTKDFEELKAEEVDVTK-------------------------DIKPQLELIEDEEK 866
Query: 636 LCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS 695
L ++ + V P +TTT + P++ P + KQ +
Sbjct: 867 LKETEPVEAYVIQKEREVTKGPAESPDEG-ITTTEGEGECEQTPEELEPVE----KQGVD 921
Query: 696 KAPEPKKPPPLVKQPTLHGSPSAKAK----QPPEADSLSKPAPPKEPSVPSEQDKAPVAD 751
+ + ++ + G KA+ + PE D P+E +++
Sbjct: 922 DIEKFEDEGAGFEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESA--- 978
Query: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811
K + ++ + V+S + D+ + + +AE+ + D A+ ++ E
Sbjct: 979 -KAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPE 1037
Query: 812 KVSPFD------SKAIPRPASDSKIISHPGPS----SESKGQKQVDPVQKKEEPKKAQTK 861
K+ D KA ++ + P+ ++S G++ + + P ++++
Sbjct: 1038 KMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETLPGGSESE 1097
Query: 862 MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921
+ A P T+G T T + S +P S ++D ++ T
Sbjct: 1098 AT----ASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDE-MSTPRDVMSDETNNEET 1152
Query: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981
+ + +S++SQ +S+ P+ S+ + G
Sbjct: 1153 ESPSQEFVNITKYESSLYSQE------------YSKPADVTPLNGFSEGSKTDATDGKDY 1200
Query: 982 STGQAPPAPAKSIPVKKETKAPAAEKL--EPKAEQAPTVKRTETEKKPPPIKDSKSLTAE 1039
+ + +P S+ K +++ + E KA +K + + + SKS +
Sbjct: 1201 NASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSLS 1260
Query: 1040 PQKAVLPTKLEKSPKPESTCPLCKTELNIG-SKDPPNFNTCTECKNQVCNLCGFNPTPHL 1098
P P+ LEK+P E + T I S + E +V +P
Sbjct: 1261 PSP---PSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPEDKT 1317
Query: 1099 TEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVK 1158
E+ ++++G G +P+ K+S +P TE + AVP +
Sbjct: 1318 LEV-------VSPSQSVTGSAGHTPYYQ-SPTDEKSSHLP--TEVIEKPPAVPVSFEFSD 1367
Query: 1159 KQEQEVKTEAEKV------ILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKK 1212
+++ + + +++ LS + PP++ ++ E DKAS +
Sbjct: 1368 AKDENERASVSPMDEPVPDSESPIEKVLSPLRSPPLIGSESAYESFLSADDKASGRGAES 1427
Query: 1213 PLPEEK------------------KLIPEEEKIRSEEKKPLLE---EKKPTPEDKKLLPE 1251
P E+ L ++++ +S + P+ E ++K T + + + +
Sbjct: 1428 PFEEKSGKQGSPDQVSPVSEMTSTSLYQDKQEGKSTDFAPIKEDFGQEKKTDDVEAMSSQ 1487
Query: 1252 AKTSAPEEQKHDLLKSQVQIAE----------EKLEGRVAPKT---VQEGKQPQT--KME 1296
+ E + D+ +Q+ +++ EG V+ K+ V EG T ME
Sbjct: 1488 PALALDERKLGDVSPTQIDVSQFGSFKEDTKMSISEGTVSDKSATPVDEGVAEDTYSHME 1547
Query: 1297 GLPS---------------------------GTPQSLPKEDDKTTKTI------------ 1317
G+ S G+P S +D + +
Sbjct: 1548 GVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMS 1607
Query: 1318 ---KEQPQPPCTAKPD-QVEPGKEKTEKEDDKSDTSS------SQQPKSPQGLSDTGYSS 1367
+E P+P + PD + K +T +D +S+ SS + P+ + + S
Sbjct: 1608 PSKEECPRPMSISPPDFSPKTAKSRTPVQDHRSEQSSMSIEFGQESPEQSLAMDFSRQSP 1667
Query: 1368 DGISSSLGEI------PSLI---PTDEKDI-----LKGLKKDSFSQESSPSSPSDLAKLE 1413
D + G + P+ + P+D +D + +++ S++Q++ S ++++E
Sbjct: 1668 DHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHKIPPMEEPSYTQDNDLSELISVSQVE 1727
Query: 1414 ---STVLSILEAQ-ASTLADEKSEKKTQPHEVSPEQPKDQEKTQSL-SETL--EITISEE 1466
ST + +Q AS L ++ P ++S EK QSL E L + IS
Sbjct: 1728 ASPSTSSAHTPSQIASPLQEDTLSDVAPPRDMSLYASLTSEKVQSLEGEKLSPKSDISPL 1787
Query: 1467 EIKESQEERKDTFKKDSQQDI--PSSKDHKEKSEFVDDITTRREPY--------DSVEES 1516
+ES TF DS + ++ H S +D EPY D+++
Sbjct: 1788 TPRESSPLYSPTF-SDSTSAVKEKTATCHSSSSPPID--AASAEPYGFRASVLFDTMQHH 1844
Query: 1517 SESENSPVPQRKRRTSVGSSSSD----EYKQEDSQGSGEEEDFIRKQIIEMSADEDASGS 1572
+ S G + D K E++ S +EED+ + + + D G
Sbjct: 1845 LALNRDLSTPGLEKDSGGKTPGDFSYAYQKPEETTRSPDEEDYDYESYEKTTRTSDVGGY 1904
Query: 1573 EDDEFIRNQLKEISSSTESQKKEETKGKGKITA--GKHRRLTRKSSTSIDEDAGRRHSWH 1630
++ R S ++S ET GK T G + + +T E+ G +
Sbjct: 1905 YYEKIERT----TKSPSDSGYSYETIGKTTKTPEDGDYSYEIIEKTTRTPEEGGYSY--- 1957
Query: 1631 DEDDEAFDESPELK-YRETKSQESEELVVTGGGGLRRFKTIELNSTIAD-KYSAESSQKK 1688
+ E PE+ Y K++ S L+ G + + T+ D YS E+++K
Sbjct: 1958 -DISEKTTSPPEVSGYSYEKTERSRRLLDDISNGYD--DSEDGGHTLGDPSYSYETTEKI 2014
Query: 1689 TSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHK 1748
TS PE E S S + + S+ + ++ +P + + E SD +
Sbjct: 2015 TSF-----PESEGYSYETSTKTTRTPDTSTYCYETAEKITRTPQASTYSYETSDLCYT-- 2067
Query: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELR------EEEELLKEQEKQREIEQQQRKS 1802
E K +AR L+ + E + EL E +E E E+ +S
Sbjct: 2068 -AEKKSPSEARQDVDLCLVSSCEYKHPKTELSPSFINPNPLEWFASEEPTEESEKPLTQS 2126
Query: 1803 SSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPS 1862
Q+ R+ +TPP+++S E A + E EE + +
Sbjct: 2127 GGAPPPPG----GKQQGRQCDETPPTSVS--ESAPSQTDSDVPPETEECPSITA---DAN 2177
Query: 1863 IESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPT---------DEQSIMQKEGSQKALK 1912
I+S+ E I +K + + + P V SP+ D +++ ++ KALK
Sbjct: 2178 IDSEDESETIPTDKTVTYKHMDPPPAPVQDRSPSPRHPDVSMVDPEALAIEQNLGKALK 2236
Score = 45.1 bits (105), Expect = 0.002
Identities = 217/1147 (18%), Positives = 371/1147 (32%), Gaps = 193/1147 (16%)
Query: 50 EEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPG 109
EE++ +A+ K S +S S +++ S P S PP P G
Sbjct: 1214 EEDKFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSLSPSPPSPLEKTPLG 1273
Query: 110 LSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSV 169
R+ + + ++ + + ++ + ++ EEH +S L V+ +V+
Sbjct: 1274 ---ERSVNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPEDKTLEVVSPSQSVTGS 1330
Query: 170 VNKFNPFDLISDSEASQEETTKKQKVVQKEQGKP------------EGIIKPPLQQQPP- 216
+ +D ++S T +V++K P E P+ + P
Sbjct: 1331 AGHTPYYQSPTDEKSSHLPT----EVIEKPPAVPVSFEFSDAKDENERASVSPMDEPVPD 1386
Query: 217 --KPIPKQQGPGRDP------------LQQDGTPKSISSQQPEKIKSQPPGTG---KPIQ 259
PI K P R P L D ++ P + KS G+ P+
Sbjct: 1387 SESPIEKVLSPLRSPPLIGSESAYESFLSADDKASGRGAESPFEEKSGKQGSPDQVSPVS 1446
Query: 260 GPTQTP---------QTDHAKLPLQRDASRPQTKQADIVRGESVKPSLP---------SP 301
T T TD A P++ D Q K+ D V S +P+L SP
Sbjct: 1447 EMTSTSLYQDKQEGKSTDFA--PIKEDFG--QEKKTDDVEAMSSQPALALDERKLGDVSP 1502
Query: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP 361
++ + Q K + E + + P + G T+
Sbjct: 1503 TQIDVSQFGSFKEDTKMSISEGTVSDKSATPVDEGVAEDTYSHMEGVASVSTASVATSSF 1562
Query: 362 PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPL 421
P P S+E +++ V +TP P+++ P+P+
Sbjct: 1563 PEPTTDDVSPSLHAEVGSPHSTEVDDSLSVS----VVQTPTTFQETEMSPSKEE-CPRPM 1617
Query: 422 AQQPGLQSPAKAPGPTKTPVQ----QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA 477
+ P SP A ++TPVQ + I Q P ++ A P G
Sbjct: 1618 SISPPDFSPKTAK--SRTPVQDHRSEQSSMSIEFGQESPEQSLAMDFSRQSPDHPTVGAG 1675
Query: 478 KPPPQQPGPAK----PPPQQPGSAK---PPSQQPGSTKP---------PPQQPGPAKPSP 521
+ GP + P Q S PP ++P T+ + P+ S
Sbjct: 1676 VLHITENGPTEVDYSPSDMQDSSLSHKIPPMEEPSYTQDNDLSELISVSQVEASPSTSSA 1735
Query: 522 QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPT-VSPSAKQPP 580
P P Q+ P A +++ V Q+ G+ L P + +SP P
Sbjct: 1736 HTPSQIASPLQE--DTLSDVAPPRDMSLYASLTSEKV-QSLEGEKLSPKSDISPLT---P 1789
Query: 581 SQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNC 640
+ P ++T + + ++ GF + ++ L LN
Sbjct: 1790 RESSPLYSPTFSDSTSAVKEKTATCHSSSSPPIDAASAEPYGFRASVLFDTMQHHLALNR 1849
Query: 641 QMKRA---------LGGDLAPVPSSPQPKLKTAP-----------VTTTSAVS------- 673
+ GD + P+ ++ T TS V
Sbjct: 1850 DLSTPGLEKDSGGKTPGDFSYAYQKPEETTRSPDEEDYDYESYEKTTRTSDVGGYYYEKI 1909
Query: 674 -KSSPQPQQTSPKKDAAPKQDLSKAPEP--------KKPPPLVKQPTLHGSPSAKAKQPP 724
+++ P + + K +K PE +K ++ S K PP
Sbjct: 1910 ERTTKSPSDSGYSYETIGKT--TKTPEDGDYSYEIIEKTTRTPEEGGYSYDISEKTTSPP 1967
Query: 725 EADSLSKPAPPKE----PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS----------- 769
E S + + + D + P TT+ ++S
Sbjct: 1968 EVSGYSYEKTERSRRLLDDISNGYDDSEDGGHTLGDPSYSYETTEKITSFPESEGYSYET 2027
Query: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSK 829
S+ TT+ S+ AE+ T P + + + T EK SP ++ R D
Sbjct: 2028 STKTTRTPDTSTYCYETAEKITRTPQASTYSYETSDLCYTAEKKSPSEA----RQDVDLC 2083
Query: 830 IISHPGPSSESKGQK-QVDPVQKKEEPKKAQTKMSPKPDA-KPMPK--GSPTPPGPRPTA 885
++S S E K K ++ P P + P ++ KP+ + G+P PPG +
Sbjct: 2084 LVS----SCEYKHPKTELSPSFINPNPLEWFASEEPTEESEKPLTQSGGAPPPPGGKQQG 2139
Query: 886 GQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL 945
Q TP S S+ S D P P T + S
Sbjct: 2140 RQCDETPPTSVSESAPSQTDS-------DVPPETEECPSITADANIDS------EDESET 2186
Query: 946 ISTAGQPGPHSQSGPGAPMK-QAPAPSQPPTSQGPPKSTG---QAPPAPAKSIPVKKETK 1001
I T P AP++ ++P+P P S P++ A K + K +TK
Sbjct: 2187 IPTDKTVTYKHMDPPPAPVQDRSPSPRHPDVSMVDPEALAIEQNLGKALKKDLKEKTKTK 2246
Query: 1002 APAAEKLEPKAEQAPTVKRTETEKKP----------PPIKDSKSLTAEPQKAVLPTKLEK 1051
P K + + VK+++ + KP D S A P+K +EK
Sbjct: 2247 KPGT-----KTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKK---KESVEK 2298
Query: 1052 SPKPEST 1058
+ KP +T
Sbjct: 2299 AAKPTTT 2305
Score = 40.0 bits (92), Expect = 0.060
Identities = 53/247 (21%), Positives = 103/247 (41%), Gaps = 25/247 (10%)
Query: 69 GSVPPAAAESPSMHRKQELDSSHPPKQSGRP-PDPGRPAQPGLSKSRTTDTFRSEQKLPG 127
G VP + + KQ DS K + +P P + T E+
Sbjct: 523 GQVPTPVVKQTKL--KQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKV 580
Query: 128 RSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQE 187
S + +K+ K +K E K S+ + S V + V + D+ +A++E
Sbjct: 581 ESKEKVMVKKDKP---IKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDV--KPKAAKE 635
Query: 188 ETTKKQKVVQKEQGK--PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTP--KSISSQQ 243
+T KK+ V+ E K E K +++ PI K++ P ++ ++++ K ++
Sbjct: 636 KTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKE 695
Query: 244 PEK-IKSQPP----------GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGE 292
P+K +K + P K ++ + P+ + KLP +DA + T ++ +
Sbjct: 696 PKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLP--KDAKKSSTPLSEAKKPA 753
Query: 293 SVKPSLP 299
++KP +P
Sbjct: 754 ALKPKVP 760
Score = 38.9 bits (89), Expect = 0.13
Identities = 65/261 (24%), Positives = 105/261 (40%), Gaps = 44/261 (16%)
Query: 539 PSAQQPSP-----AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ----PP---SQGLP- 585
PS P+P ++ ++S KP++Q+G P PP +Q PP S+ P
Sbjct: 2099 PSFINPNPLEWFASEEPTEESEKPLTQSGGAPP--PPGGKQQGRQCDETPPTSVSESAPS 2156
Query: 586 KTICPLCNTTELLLHVPEKANFNTCTECQT-----TV---------CSLCGFNPNPHLTE 631
+T + TE + AN ++ E +T TV + +P+P +
Sbjct: 2157 QTDSDVPPETEECPSITADANIDSEDESETIPTDKTVTYKHMDPPPAPVQDRSPSPRHPD 2216
Query: 632 VK----EWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSS--PQPQQTSPK 685
V E L + + +AL DL + +P KT ++S V KS +P SPK
Sbjct: 2217 VSMVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTK---SSSPVKKSDGKSKPLAASPK 2273
Query: 686 ----KDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVP 741
K+++ K +S+ PKK + K +P KA + E D +K A S
Sbjct: 2274 PAGLKESSDK--VSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKS 2331
Query: 742 SEQDKAPVADDKPKQPKMVKP 762
++ A K + V P
Sbjct: 2332 AKTATAGPGTTKTTKSSAVPP 2352
Score = 38.5 bits (88), Expect = 0.17
Identities = 119/641 (18%), Positives = 222/641 (34%), Gaps = 99/641 (15%)
Query: 3449 DEDATDRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSMTEADKTK 3508
++ ATD + + +T K +T V+ +D+ ++ + + K V K D + K
Sbjct: 622 EKQATDVKPKAAKEKTVKK-ETKVKPEDKKEE------KEKPKKEVAKKEDKTPIKKEEK 674
Query: 3509 PLSKVSSIAVQTVAEISVQTEPVGTIR--TPSIRARVDAKVEIIKHISAPEKTYKGGSLG 3566
P + V+ + + EP ++ TP + + K E K + EK K
Sbjct: 675 PKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKK 734
Query: 3567 CQTEAD------SDTQSPQYLSATSPPKDK------------KRPTPLEIGYSSHLRADS 3608
+A S+ + P L P K++ K +++ A++
Sbjct: 735 LPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEA 794
Query: 3609 TVQLAPSPPKSPKVLYSP-ISPLSPGKALESAFVPYEKP----------------LPDDI 3651
+ + V+ + I+ + P K LE+ P + DI
Sbjct: 795 VAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDI 854
Query: 3652 SPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTM 3711
PQ L D K+ P A ++Q+ K + + DE G T
Sbjct: 855 KPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPAESPDE---------------GITTT 899
Query: 3712 TSSGAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELD 3771
G ++ L P E+ F G + +A+ + + E D
Sbjct: 900 EGEGECEQTPEEL--EPVEKQGVDDIEKFEDEGAGFEESSETGDYEEKAETEEAEEPEED 957
Query: 3772 LVERESAKLRKKQAELDEEEKEIDA------KLRYLEMGINRRKEALLKEREKRERAYLQ 3825
E K DEE + +A K + G +R +E + + EK E +
Sbjct: 958 GEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSE 1017
Query: 3826 GVAEDRDYMSDSEVSSTRPTRIESQHGI-----ERPRTAPQTEFSQFIPPQTQTESQLVP 3880
A++ D D+ P ++E++ + + E F+ T+ P
Sbjct: 1018 EEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSP 1077
Query: 3881 PTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQV 3940
P + + +++ + + + + E Q S Y TQ T ++
Sbjct: 1078 GREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSGY-TQSTI----------EI 1126
Query: 3941 QPTPTPQPSYQLPSQMMVIQ------QKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTD 3994
PTP P +M + + P Q + + +S Y ++P + P+
Sbjct: 1127 SSEPTPMDEMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADVTPL--- 1183
Query: 3995 NTFAVSHLGSKYNSLDLRIGLEERSSMAS-SPISSISADSF 4034
N F+ GSK ++ D G + +S ++ SP SS+ D F
Sbjct: 1184 NGFSE---GSKTDATD---GKDYNASASTISPPSSMEEDKF 1218
Score = 37.7 bits (86), Expect = 0.30
Identities = 50/215 (23%), Positives = 75/215 (34%), Gaps = 22/215 (10%)
Query: 381 PSSEQPGPK---ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437
PS P P A +P + P Q G A PP + + P AP T
Sbjct: 2099 PSFINPNPLEWFASEEPTEESEKPLTQSGGAPPPPGGKQQGRQCDETPPTSVSESAPSQT 2158
Query: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL-------PGPAKPPPQQPGPAKPP 490
+ V P + P+ A S ++ T P + P PA + P P P
Sbjct: 2159 DSDVP-PETEECPSITADANIDSEDES-ETIPTDKTVTYKHMDPPPAPVQDRSPSPRHPD 2216
Query: 491 PQQ--PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548
P + + K ++ K + S+ P + G +KP A P PA
Sbjct: 2217 VSMVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPA- 2275
Query: 549 PSAQQSTKPVSQTGSGKPLQ------PPTVSPSAK 577
++S+ VS+ S K + PT +P K
Sbjct: 2276 -GLKESSDKVSRVASPKKKESVEKAAKPTTTPEVK 2309
Score = 37.4 bits (85), Expect = 0.39
Identities = 64/304 (21%), Positives = 99/304 (32%), Gaps = 80/304 (26%)
Query: 184 ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243
AS+E T + +K + + G P P P KQQG D + P S+S
Sbjct: 2111 ASEEPTEESEKPLTQSGGAP------------PPPGGKQQGRQCD----ETPPTSVSESA 2154
Query: 244 PEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSK 303
P + S P P+T+ + DA+ + E ++P+
Sbjct: 2155 PSQTDSDVP------------PETEECP-SITADAN---------IDSEDESETIPTDKT 2192
Query: 304 PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPG-TVKPPVQPPGTTKPP 362
+ P PPA S P P L + Q G +K ++ TK P
Sbjct: 2193 VTYKHMDP--PPAPVQDRSPSPRHPDVSMVDPEALA--IEQNLGKALKKDLKEKTKTKKP 2248
Query: 363 AQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422
+ P + G KP + P P L + + +V +PK
Sbjct: 2249 GTKTKSSSPVKKSDGKSKPLAASPKPAGLKE--------------SSDKVSRVASPKK-- 2292
Query: 423 QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ-----------------AGPGKTSAQQTG 465
+S KA PT TP + G+ ++ AGPG T ++
Sbjct: 2293 ----KESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTTKSS 2348
Query: 466 PTKP 469
P
Sbjct: 2349 AVPP 2352
Score = 37.4 bits (85), Expect = 0.39
Identities = 70/289 (24%), Positives = 96/289 (33%), Gaps = 62/289 (21%)
Query: 88 DSSHPPKQSG-RPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKE 146
+S P QSG PP PG G + R D +P T + + S+TD
Sbjct: 2118 ESEKPLTQSGGAPPPPG-----GKQQGRQCD----------ETPPTSVSESAPSQTDSDV 2162
Query: 147 EHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGI 206
++ P ++ N DSE + ET K V + P
Sbjct: 2163 PPETEECPSITADANI------------------DSE-DESETIPTDKTVTYKHMDP--- 2200
Query: 207 IKPPLQQQPPKPIPKQQGPGR-DP---LQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT 262
PP Q P P+ DP + K++ EK K++ PGT P
Sbjct: 2201 --PPAPVQDRSPSPRHPDVSMVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTKSSSPV 2258
Query: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSK----PPIQQPTPGKPPAQQ 318
+ ++D PL A+ P K A + + SP K +PT
Sbjct: 2259 K--KSDGKSKPL---AASP--KPAGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVKAA 2311
Query: 319 PGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG 367
G EK + A S K PGT K TTK A P G
Sbjct: 2312 RGEEKDKETKNAANASASKSAKTATAGPGTTK-------TTKSSAVPPG 2353
Score = 36.6 bits (83), Expect = 0.66
Identities = 45/177 (25%), Positives = 68/177 (38%), Gaps = 44/177 (24%)
Query: 3562 GGSLGCQTEADSDTQSPQYLSATSPP----KDKKRPTPLEIGYSSHLRADSTVQLAPS-- 3615
G S G +T+A S SPP +DK + L Y S ++A +T+ + S
Sbjct: 1185 GFSEGSKTDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSIS 1244
Query: 3616 --------PPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPA 3667
P KSP + SP SPL E+ + ++P ++ A+V P
Sbjct: 1245 AVSSEKVSPSKSPSLSPSPPSPLEKTPL-------GERSVNFSLTPNEIKVSAEAEVAPV 1297
Query: 3668 SP----------------KTAKMMQRSMS-------DPKPLSPTADESSRAPFQYTE 3701
SP KT +++ S S P SPT ++SS P + E
Sbjct: 1298 SPEVTQEVVEEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVIE 1354
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 119 bits (299), Expect = 6e-26
Identities = 261/1259 (20%), Positives = 439/1259 (34%), Gaps = 203/1259 (16%)
Query: 2050 TSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLTSS 2109
T+TE + + L+ + +TP +SP + + +S + S + +
Sbjct: 789 TTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPT 848
Query: 2110 VLSGASLTDSTSS-----------ATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIA 2158
G S+ ST S +T + I+ +T VT+ T
Sbjct: 849 PAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTT 908
Query: 2159 HESLILTYSEPSESAT---SVPPSDTPSLTSSVSSVCTT--DSSSPITTLDSIT------ 2207
E + S P E +T S+P S TP ++S ++ T D+S+P+TT T
Sbjct: 909 SEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTA 968
Query: 2208 ---------------------------------TVYTEPVDMITKFEDSEEISSSTYFPG 2234
T+ T PVD T S E SS
Sbjct: 969 EGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPP---- 1024
Query: 2235 SIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLL 2294
P S+ + P +G + +S + +ASS ++ P ADT +
Sbjct: 1025 -----PTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTP----ADTSTPVTT 1075
Query: 2295 ISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKE 2354
S+ + T +G + L + + L V S++ P+
Sbjct: 1076 YSQAS----SSSTTADGTSMPTSTYSEGSTPLTSVPVSTRL---VVSSEASTLSTTPVDT 1128
Query: 2355 QLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPF------------FRSSSLDIS 2402
+ T T + + +P+ PS + P P ++ +D
Sbjct: 1129 SIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSK 1188
Query: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVAS---------PVTTAT 2453
Q PPP P P S T +P + VAS PV T+T
Sbjct: 1189 TQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTST 1248
Query: 2454 PLFDAVTTLETTAVLRSNGLP----------VTRICTTAPPPVPPKPSSIPSGLVFTHRP 2503
P+ + T + LP +T I + P+ S++ + V T P
Sbjct: 1249 PVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGP 1308
Query: 2504 EPSKPPIAPKPVIPQ---LPTTT----QKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPS 2556
+ ++ P + +PT+T + P P T L +S++++ T D P
Sbjct: 1309 VVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPV 1368
Query: 2557 PTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSV 2616
TS + SSP S+ T + + PSE TP S +++ P+ S +S
Sbjct: 1369 TTSTEAC----SSPTTSEG---TSMPNSNPSEGTTPLTSIP---VSTTPVVSSEASTLSA 1418
Query: 2617 EPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSK 2676
PV + P T+ E S IS ++TP + ++ P S T +E S
Sbjct: 1419 TPVDTSTPGTTSAEATSSPTTAEGISIP----TSTPSEGKTPLKSIPVSNTPVANSEAST 1474
Query: 2677 TEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKV 2736
+ S +P V +S +++ P P +I + P +G L + TV
Sbjct: 1475 LSTTPVDSNSPVV--TSTAVSSSPTPAEGTSIAISTPS---EGSTALTSIPVSTTTVASS 1529
Query: 2737 EVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTPV-SLATETV 2795
E+ + LS + +T + + + S S TP+ SL T+
Sbjct: 1530 EINS------LSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTM 1583
Query: 2796 TFVTCTASASYTTGTESLVGAEHAMTTPLQLTTSKHAEPPYRIPSD----------QVFP 2845
V+ A+ TT +S A T TT++ + PS+ P
Sbjct: 1584 LVVSSEANTLSTTPIDSKTQVT-ASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTP 1642
Query: 2846 IAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKS 2905
+A EA + +++ + T+ + P ST ++G T T+ +
Sbjct: 1643 VASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTP------LTSIT 1696
Query: 2906 HRTVVTMDESTSSVMTKIIEDEKPVDL-TAGRRAVCCDVVYKLPFGRSCTAQQPATTLPE 2964
RT + S++ T +++ PV T R + +P P T++P
Sbjct: 1697 VRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPV 1756
Query: 2965 DRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLAEAGHFFYKSKNAFDYSEGTDTAVD 3024
P +S +EA S D S T+ +
Sbjct: 1757 ST------------------------TPVLS----SEASTL---SATPIDTSTPVTTSTE 1785
Query: 3025 LTSGRVTT-GEVMDYSSKTTGPYPETRQVISGAGISTPQYSTARMTPPPGPQYCVGSVLR 3083
TS T G + S+ + G P T +S ++ + ST TP V S
Sbjct: 1786 ATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAV 1845
Query: 3084 SSNGVVY--SSVATPTPS--TFAITTQPGSIFSTTVRDLSGIHTADAVTSLPAMHHSQ-- 3137
SS+ +S+AT TPS + A+T+ P S + + + + T AVTS P ++Q
Sbjct: 1846 SSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVS 1905
Query: 3138 ----PMPRSYFITTGASETDIAVTGIDIS----ASLQTITMESLTAETIDSVPTLTTAS 3188
S T+ E +T I +S AS + T+ + A+T V T + AS
Sbjct: 1906 SSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQAS 1964
Score = 119 bits (297), Expect = 1e-25
Identities = 292/1310 (22%), Positives = 454/1310 (34%), Gaps = 215/1310 (16%)
Query: 2080 SSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTE 2139
SSPT A G M ST R P S+ S + AS +T S TL+ +T + ++
Sbjct: 1906 SSPTTAD-GSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTY--SQ 1962
Query: 2140 EIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTT--DSS 2197
D T YSE S TS+P S T ++S S++ TT D+S
Sbjct: 1963 ASSSPTTADGTSMPTP---------AYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTS 2013
Query: 2198 SPITT---------------LDSIT------------------------TVYTEPVDMIT 2218
+P TT + + T T+ T PVD T
Sbjct: 2014 TPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKT 2073
Query: 2219 KFEDSEEISSSTYFPGS--IIDYPEE-------ISVSLDRTAPPDGRASADHIVISLSDM 2269
+ +S E SSS GS I P E I +S A P+ + V S S +
Sbjct: 2074 QVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPV 2133
Query: 2270 ASSIIESVVPKP-EG------------------PVADTVSTDLLIS--EKDPVKKAKKET 2308
+S S P P EG PV+ TV IS PV + T
Sbjct: 2134 ITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVT 2193
Query: 2309 GNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKE---------QLSTT 2359
+ E + + + S T F P S + + E ST
Sbjct: 2194 NS---TEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTP 2250
Query: 2360 YFTSGETF-------GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP- 2411
TS E G P S L G+ ++S+P S +S P P
Sbjct: 2251 VTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPF 2310
Query: 2412 --PPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLR 2469
PPP +P TS + P ++ PV+T +TL TT
Sbjct: 2311 TTSTEASSPPPTAEGTSMPTSTSSEGN-TPLTRM----PVSTTMVASFETSTLSTTPA-- 2363
Query: 2470 SNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVI-PQLPTTTQKPTD 2528
PVT P +S+P+ + P++ PV+ + T + P D
Sbjct: 2364 DTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVD 2423
Query: 2529 IH-PKPTGLSLTSSMTLNLVTSADYKLPSP-TSPLSPHSNKSSPRFSK---SLTETYVVI 2583
P T +SS T TS PS T+PL+ ++P S +L+ T V
Sbjct: 2424 TSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDT 2483
Query: 2584 TLPSEPGTPTDSSASQA---------------------ITSWPLGSPSKDLVSVEPVFSV 2622
+ P T SS + A +++ P+ SP +S PV S
Sbjct: 2484 STPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSN 2543
Query: 2623 VPPVTAVEIPISSEQTFYISGALQTFS--ATPV------TAPSSFQAAPTSVTQFLTTEV 2674
P VT+ EI S+ S T+S +TP+ T P + A T T + T +
Sbjct: 2544 SPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSI 2603
Query: 2675 SKTEVSATRSTAPSVGLSSISITIPPE-PLALDNIHLEKPQYKEDGKLQLVGDVIDLRT- 2732
T + T S+ + +S+ I+ P E +L +I + L +D RT
Sbjct: 2604 PVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTL 2663
Query: 2733 ------------------------------VPKVEVKTT----DKCIDLSASTMDVKRQI 2758
+ + V TT + LS + +D +
Sbjct: 2664 VTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPV 2723
Query: 2759 TANEVYGKQISAVQPSIINLSVTSSIVTPV-SLATETVTFVTCTASASYTTGTESLVGAE 2817
T + + + + + +S S TP+ S+ T+ + AS TT ++ +
Sbjct: 2724 TTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVT 2783
Query: 2818 HAMTTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPV 2877
+ TT++ P PS+ P+ P+N + + A TL+ T T PV
Sbjct: 2784 TSTEASSSPTTAEVTSMPTSTPSETSTPLT--SMPVNHTPVASSEAGTLSTTPVDTSTPV 2841
Query: 2878 GVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVT---------MDESTSSVMTKIIEDEK 2928
+ T ++ S +G VV +ST T++T S++ T ++
Sbjct: 2842 TTS---TKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSI 2898
Query: 2929 PVDL-TAGRRAVCCDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGI 2987
PV T G + +P P T++ + P R
Sbjct: 2899 PVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTP 2958
Query: 2988 GGMKPSMSDTNLAEAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYP 3047
S + G + S + LTS V+T V + T P
Sbjct: 2959 VTTSAEASSSPTTAEG-------TSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTP 3011
Query: 3048 -ETRQVISGAGISTPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQ 3106
+T ++ + ++ +TA T P GS +S V + VA P ST + T
Sbjct: 3012 ADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPV 3071
Query: 3107 PGSIFSTTVRDLSGIHTADAVTSLPAMHHSQ------PMPRSYFITTGASETDIAVTGID 3160
+ T ++S T TS+P +S+ +P S T ++ + ++ T +D
Sbjct: 3072 DSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVD 3131
Query: 3161 ISASLQTIT--MESLTAETIDSVPTLTTASEVFPEVVGDESALLIVPEED 3208
S + T T S T S+PT T + P S +L+V ED
Sbjct: 3132 TSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSED 3181
Score = 116 bits (290), Expect = 7e-25
Identities = 268/1198 (22%), Positives = 426/1198 (35%), Gaps = 148/1198 (12%)
Query: 2080 SSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQH---- 2135
S PT P ++M MP AS +S LS + ST T S T
Sbjct: 500 SMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTS 559
Query: 2136 --FSTEEIEDEYVTDYTREIQEIIAHES------------LILTYSEPSESATSVPPSDT 2181
ST +T+ + +++ E+ + T SE S S+T+ +
Sbjct: 560 IPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSM 619
Query: 2182 PSLTSSVSSVCTTDSSSPITTLDS--ITTVYTEPVDMITKFEDSEEI-SSSTYFPGSIID 2238
P+ T S T S T + S +T+ T PVD T S E SSST G+ +
Sbjct: 620 PTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMP 679
Query: 2239 YPEEISVSLDRTAPPDGR---ASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLI 2295
S T+ P AS++ +S + + +S V E + T + +
Sbjct: 680 TSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTST--PVTTSTEASSSPTTADGASM 737
Query: 2296 SEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQ 2355
P + + T + K L S+LS T D S+ I +
Sbjct: 738 PTSTPSEGSTPLTSMPV----------SKTLLTSSEASTLSTTPLD--TSTHITTSTEAS 785
Query: 2356 LSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP 2415
S T T G P S GSP ++S+P P + +S P P
Sbjct: 786 CSPT-----TTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTS 840
Query: 2416 PPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPV 2475
P P + P T + + PV+T A++TL TT V S PV
Sbjct: 841 TEVSSSPTPAE--GTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTST--PV 896
Query: 2476 TRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIP-QLPTTTQKPTDIH-PKP 2533
T P + +S+P+ + P + PV+ + T + P D P
Sbjct: 897 TNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVT 956
Query: 2534 TGLSLTSSMTLNLVTSADYKLPSP-TSPLSPH-------SNKSSPRFSKSLTETYVVITL 2585
T TSS T TS PS T+PL+ +N + S + ++ +T
Sbjct: 957 TSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTT 1016
Query: 2586 PSEPGTP------------TDSSASQAITSWPLG-----SPSKDLVSVEPVFSVVPPVTA 2628
+E +P T S S +T P+ S +S P + P T
Sbjct: 1017 STEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTY 1076
Query: 2629 VEIPISSEQTFYISGALQTFS--ATPVTA-PSSFQAAPTSVTQFLTTEVSKTEVSATRST 2685
+ SS S T+S +TP+T+ P S + +S L+T T + T ST
Sbjct: 1077 SQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTST 1136
Query: 2686 -APSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKC 2744
A S ++ +IP P +G L + V E T
Sbjct: 1137 EASSSPTTAEGTSIPTSP-------------PSEGTTPLASMPVSTTLVVSSEANT---- 1179
Query: 2745 IDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASA 2804
LS + +D K Q+ + + + + S TP+ T T AS+
Sbjct: 1180 --LSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPL---TSMPVRHTPVASS 1234
Query: 2805 SYTTGTESLVGAEHAMTTPLQLTTSKHAEPPYRIPSDQVFPIAR--EEAPINLSLGTPAH 2862
+T + S V +TT + ++S +P+ + P++ +L T
Sbjct: 1235 EASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPE 1294
Query: 2863 AVTLAITKPVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVT-MDESTSSVMT 2921
A TL T T PV +N + S +G + ST RT +T + +T+ V +
Sbjct: 1295 ASTLLTTPVDTKGPVVTSNEVSSSPTP---AEGTSMPTSTYSEGRTPLTSIPVNTTLVAS 1351
Query: 2922 KIIE--DEKPVDLTAGRRAVCCDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRS 2979
I PVD + P S A TT + S
Sbjct: 1352 SAISILSTTPVDNST-------------PVTTSTEACSSPTT---------SEGTSMPNS 1389
Query: 2980 GPY-GYRGIGGMKPSMSDTNLAEAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTT-GEVMD 3037
P G + + S + +EA S D S T+ + TS T G +
Sbjct: 1390 NPSEGTTPLTSIPVSTTPVVSSEASTL---SATPVDTSTPGTTSAEATSSPTTAEGISIP 1446
Query: 3038 YSSKTTGPYPETRQVISGAGISTPQYSTARMTPPPGPQYCVGSVLRSSNGVVYS----SV 3093
S+ + G P +S ++ + ST TP V S SS+ ++
Sbjct: 1447 TSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAI 1506
Query: 3094 ATPTPSTFAITTQPGSIFSTTVRDLSGIHTADAVTSLPAMHHSQPMPR------SYFITT 3147
+TP+ + A+T+ P S + +++ + T AVTS P +SQ + T+
Sbjct: 1507 STPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTS 1566
Query: 3148 GASETDIAVTGIDISASLQTITMESLTAET--IDSVPTLTTASEVFPEVVGDESALLI 3203
SE +T + +S L ++ E+ T T IDS +T ++E + S++ I
Sbjct: 1567 TYSEGSTPLTSLPVSTML-VVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTI 1623
Score = 114 bits (286), Expect = 2e-24
Identities = 257/1235 (20%), Positives = 433/1235 (35%), Gaps = 167/1235 (13%)
Query: 2043 VDLGTMVTSTEEERKLLDADAAY---------EELMKRQQMQLTPGSSPTQAPIGEDMTE 2093
VD T VT++ E A+ + L+ + TP +SP + + +
Sbjct: 2069 VDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVD 2128
Query: 2094 STMDFDRMPDASLTSSVLSGASLTDSTSS-----------ATLSIPDVKITQHFSTEEIE 2142
S + S + G S+ ST S +T + I+ +T
Sbjct: 2129 SNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDT 2188
Query: 2143 DEYVTDYTREIQEIIAHESLILTYSEPSESAT---SVPPSDTPSLTSSVSSVCTT--DSS 2197
VT+ T E + S PSE +T S+P S P +TS S++ T D+S
Sbjct: 2189 STPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTS 2248
Query: 2198 SPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRA 2257
+P+TT +E SS T G+ I + +L P
Sbjct: 2249 TPVTT-------------------STEATSSPTTAEGTSIP-----TSTLSEGTTPLTSI 2284
Query: 2258 SADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEV- 2316
H +++ S++++ V + S+ +E + + GN + +
Sbjct: 2285 PVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMP 2344
Query: 2317 ----LEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKP 2372
+ A + L +S T + SS ++TY + G T P
Sbjct: 2345 VSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTY-SEGSTPLTSVP 2403
Query: 2373 ASQLPSGSPSVSSLPAKP-------RPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP 2425
S +P S S+ P +SS +A+ P PP P P
Sbjct: 2404 VSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPV 2463
Query: 2426 PLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPP 2485
P S + L + ++P+TT+T + TT E V S + + T+ P
Sbjct: 2464 STTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSI--P 2521
Query: 2486 VPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLN 2545
V P + P + P S P+ I T+ + G S+ +S
Sbjct: 2522 VSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAE----------GTSMPTS---- 2567
Query: 2546 LVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQA-ITSW 2604
T ++ P + P+S SS + +L+ T V ++P T T SS + A TS
Sbjct: 2568 --TYSEGSTPLRSMPVSTKPLASSE--ASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSM 2623
Query: 2605 PLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQT---FSATPVTAPSSFQA 2661
P+ +PS+ S+ + PV + E S + T S++P TA S +
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGS--S 2681
Query: 2662 APTSVTQFLTTEVSKTEVSAT---RSTAPSVGLSSISITIP----------PEPLALDNI 2708
PTS +T ++ VS T S A ++ + + + P P ++
Sbjct: 2682 MPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSM 2741
Query: 2709 HLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQI 2768
+ P DG L ++ V E T +S + +D +T +
Sbjct: 2742 RISTP---SDGSTPLTSILVSTLPVASSEAST------VSTTAVDTSIPVTTSTEASSSP 2792
Query: 2769 SAVQPSIINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAMTTPLQLTT 2828
+ + + + S S TP+ T V T AS GT S + T +TT
Sbjct: 2793 TTAEVTSMPTSTPSETSTPL-----TSMPVNHTPVASSEAGTLSTTPVD----TSTPVTT 2843
Query: 2829 SKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPPVGVTNGWTDSTV 2888
S A V PI+ L P +A ++ T+ V +T
Sbjct: 2844 STKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTS 2903
Query: 2889 SQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVCCDVVYKLP 2948
++G + +T + ++ S+ +T I+ PV + V + P
Sbjct: 2904 TEGSSSP-----TTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTP 2958
Query: 2949 FGRSCTAQQPATT-----LPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLAEAG 3003
S A TT +P G +R P + M + S+ +
Sbjct: 2959 VTTSAEASSSPTTAEGTSMPISTPG--------ERRTPLTSMSVSTMPVASSEASTL--- 3007
Query: 3004 HFFYKSKNAFDYSEGTDTAVDLTSGRVTT-GEVMDYSSKTTGPYPETRQVISGAGISTPQ 3062
S+ D S T+ + +S T G + S+ + G P T +S ++ P+
Sbjct: 3008 -----SRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPE 3062
Query: 3063 YSTARMTPPPGPQYCVGSVLRSSNGV----------VYSSVATPTP----STFAITTQPG 3108
ST TP V S SS+ YS +TP ST +T+
Sbjct: 3063 ASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAI 3122
Query: 3109 SIFSTTVRDLS-GIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQT 3167
S STT D S + T+ S P MP T+ SE +T + +S L
Sbjct: 3123 STLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMP-----TSTPSEGSTPLTYMPVSTMLVV 3177
Query: 3168 ITMES-LTAETIDSVPTLTTASEVFPEVVGDESAL 3201
+ +S L+A +D+ +TT++E + +++
Sbjct: 3178 SSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSI 3212
Score = 108 bits (271), Expect = 1e-22
Identities = 268/1221 (21%), Positives = 428/1221 (35%), Gaps = 161/1221 (13%)
Query: 2078 PGSSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFS 2137
P S PT A M ST+ P LT+ +S + S +S T +IP T
Sbjct: 371 PSSLPTTAE-ATSMLTSTLSEGSTP---LTNMPVSTILVASSEASTTSTIPVDSKT---- 422
Query: 2138 TEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESAT---SVPPSDTPSLTSSVSSVCTT 2194
+VT + E + S PSE +T S+P S TP +S S++ TT
Sbjct: 423 -------FVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTT 475
Query: 2195 --DSSSPITT-LDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTA 2251
DS + +TT ++ ++ T V+ + SE + T S + + +L T
Sbjct: 476 PVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLS-TT 534
Query: 2252 PPDG----RASADHIVISLSDMASSIIESVVPKPEGPVAD-TVSTDLLISEKDPVKKAKK 2306
P D S++ S + +SI S + P+ + VST L++S +
Sbjct: 535 PVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTP 594
Query: 2307 ETGNGIILEVLEAYRDKKELE---------AER----TKSSLSETVFDHPPSSVIALPMK 2353
N + EA E +ER T S+S T+ +S ++
Sbjct: 595 ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPV 654
Query: 2354 EQ----LSTTYFTSGETF--GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPP 2407
+ ++T TS T G P S GS ++S+P S + +S P
Sbjct: 655 DSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVD 714
Query: 2408 PPPP------------------PPPPPPPPPPPPPPPLPPP----TSPKPTILPKKKLTV 2445
P P P P +P TS + + L L
Sbjct: 715 TSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDT 774
Query: 2446 ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEP 2505
++ +TT+T + TT E T++ S + + T+ P + P S P + P
Sbjct: 775 STHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTS--PEASTLSTTPVD 832
Query: 2506 SKPPIAPKPVIPQLPTT---TQKPTDIHPK-PTGLSLTSSMTLNLVTSADYKL-PSPTSP 2560
S P+ + PT T PT + + T L+ T + TSA L +P
Sbjct: 833 SNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDT 892
Query: 2561 LSPHSNKSSPRFSKSLTE-TYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPV 2619
+P +N + R S + +E T + + P E TP S ++ P+ S +S PV
Sbjct: 893 STPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPD---STTPVVSSEARTLSATPV 949
Query: 2620 FSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEV 2679
+ P T+ E +S T ++ T +TP + + P S T +E S
Sbjct: 950 DTSTPVTTSTE--ATSSPTTAEGTSIPT--STPSEGTTPLTSTPVSHTLVANSEASTLST 1005
Query: 2680 SATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVK 2739
+ S P +S + PP ++ P +G L + V E
Sbjct: 1006 TPVDSNTPLT--TSTEASSPPPTAEGTSMPTSTP---SEGSTPLTRMPVSTTMVASSETS 1060
Query: 2740 TTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTPV-SLATETVTFV 2798
T LS + D +T + + + S S TP+ S+ T V
Sbjct: 1061 T------LSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVV 1114
Query: 2799 TCTASASYTTGTESLVGAEHAMTTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLG 2858
+ AS TT ++ + + TT++ P PS+ P+A P++ +L
Sbjct: 1115 SSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLA--SMPVSTTLV 1172
Query: 2859 TPAHAVTLAI------------TKPVTVPPVGVTNGWTDSTVSQ-------------GIT 2893
+ A TL+ T+ + PP ST + +
Sbjct: 1173 VSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVA 1232
Query: 2894 DGEVVDLSTTK-SHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVCCDVVYKLPFGRS 2952
E LST+ T VT TSS T P T+ + + S
Sbjct: 1233 SSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTS 1292
Query: 2953 CTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIG--------GMKPSMS---DTNLAE 3001
A TT P D G + S P G G P S +T L
Sbjct: 1293 PEASTLLTT-PVDTKGPVVTSNEVS-SSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVA 1350
Query: 3002 AGHFFYKSKNAFDYSEGTDTAVDLTSGRVTT-GEVMDYSSKTTGPYPETRQVISGAGIST 3060
+ S D S T+ + S T+ G M S+ + G P T +S + +
Sbjct: 1351 SSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVS 1410
Query: 3061 PQYSTARMTP--PPGPQYCVGSVLRSSNGVVYSSVATPTPS-------------TFAITT 3105
+ ST TP P S S+ T TPS T +
Sbjct: 1411 SEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANS 1470
Query: 3106 QPGSIFSTTVRDLSGIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASL 3165
+ ++ +T V S + T+ AV+S P P + + SE A+T I +S
Sbjct: 1471 EASTLSTTPVDSNSPVVTSTAVSSSPT-----PAEGTSIAISTPSEGSTALTSIPVS--- 1522
Query: 3166 QTITMESLTAETIDSVPTLTT 3186
T T+ S ++ + P +T+
Sbjct: 1523 -TTTVASSEINSLSTTPAVTS 1542
Score = 98.2 bits (243), Expect = 2e-19
Identities = 275/1199 (22%), Positives = 443/1199 (36%), Gaps = 169/1199 (14%)
Query: 2080 SSPTQAPIGEDMTESTMDFDRMPDASLTSSVL---SGASLTDSTSSATLSIPDVKITQHF 2136
SSPT A G ++ S P + SV+ S + T ST+ A +IP + T+
Sbjct: 255 SSPTTAE-GPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEAS 313
Query: 2137 STEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVS--SVCTT 2194
S+ T E I TY+E S TS P S P TS +S S+
Sbjct: 314 SSPT---------TAEGTSIPTS-----TYTEGSTPLTSTPASTMPVATSEMSTLSITPV 359
Query: 2195 DSSSPITTLDSITTVYT--EPVDMITK-----------------FEDSEEISSSTYFP-- 2233
D+S+ +TT +++ T E M+T S E S+++ P
Sbjct: 360 DTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVD 419
Query: 2234 -GSIIDYPEEIS--------VSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKP-EG 2283
+ + E S S+ + P +G + +S + +ASS ++ P +
Sbjct: 420 SKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDS 479
Query: 2284 PVADTVSTDLLIS----EKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETV 2339
T ST+ S E + + + G+ + + + EA S+LS T
Sbjct: 480 KTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEA----STLSTTP 535
Query: 2340 FD--------HPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQ---LPSGSPSVSSLPA 2388
D SS P + T+ + G T P S + S + + S+ PA
Sbjct: 536 VDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPA 595
Query: 2389 KPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT----SPKPTILPKKKLT 2444
F +SS S+ P + T S + + L +
Sbjct: 596 DSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVD 655
Query: 2445 VASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPE 2504
+PVTT+T + TT E T++ S + T+ P SS S L T P
Sbjct: 656 SNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTT--PV 713
Query: 2505 PSKPPIAPKPVIPQLPTT---TQKPTDIHPKPTGLSLTS-SMTLNLVTSADYKLPSPTSP 2560
+ P+ PTT PT P LTS ++ L+TS++ S T+P
Sbjct: 714 DTSTPVTTSTEASSSPTTADGASMPTST-PSEGSTPLTSMPVSKTLLTSSEASTLS-TTP 771
Query: 2561 L--SPH-SNKSSPRFSKSLTE-TYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSV 2616
L S H + + S + TE T + I+ PSE G+P +S +IT P+ SP +S
Sbjct: 772 LDTSTHITTSTEASCSPTTTEGTSMPISTPSE-GSPLLTSIPVSIT--PVTSPEASTLST 828
Query: 2617 EPVFSVVPPVTAVEIPISSEQTFYISGALQTFS--ATPVTA-PSSFQAAPTSVTQFLTTE 2673
PV S P T+ E+ S S T+S TP+T+ P S TS L+T
Sbjct: 829 TPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTT 888
Query: 2674 VSKTEVSATRST-APSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRT 2732
T T ST A S +S ++P +G L
Sbjct: 889 PVDTSTPVTNSTEARSSPTTSEGTSMPTST-------------PGEGSTPLTSMPDSTTP 935
Query: 2733 VPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTPVSLAT 2792
V E +T LSA+ +D +T + + + + I S S TP+ T
Sbjct: 936 VVSSEART------LSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPL---T 986
Query: 2793 ETVTFVTCTASASYTTGTESLVGAEHAMTTPLQLT----TSKHAEPPYRIPSDQVFPIAR 2848
T T A++ +T + + V + +TT + + T++ P PS+ P+ R
Sbjct: 987 STPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTR 1046
Query: 2849 EEAPINLSLGTPAHAVTLAITKPVTVPPVGVTNGWTDSTVSQGITDGEVVDLSTTKSHRT 2908
P++ ++ + TL+ T T PV ++ ++ S DG + ST T
Sbjct: 1047 --MPVSTTMVASSETSTLSTTPADTSTPV---TTYSQASSSSTTADGTSMPTSTYSEGST 1101
Query: 2909 VVTMDESTSSVMTKIIEDEKPVDLTAGRRAVCCDVVYKLPFGRSCTAQQPATTLPEDRFG 2968
+T + V T+++ + L+ V +P S A TT
Sbjct: 1102 PLT----SVPVSTRLVVSSEASTLST------TPVDTSIPVTTSTEASSSPTTA------ 1145
Query: 2969 YRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLAEAGHFFYKSKNAFDYSEGTDTAVDLTSG 3028
+ S P G + T L + S D T+ + S
Sbjct: 1146 ---EGTSIPTSPP--SEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE-ASS 1199
Query: 3029 RVTTGEVMDYSSKTTG--PYPETRQVISGAGISTPQYSTARMTP-------------PPG 3073
T EV + T G P T + +++ + ST +P
Sbjct: 1200 PPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSS 1259
Query: 3074 PQYCVGSVLRSSNGVVYSSVATPTP-STFAITTQPGSIFSTTVRDLSG-IHTADAVTSLP 3131
P G+ L +S S++ T P ST +T+ S TT D G + T++ V+S P
Sbjct: 1260 PTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSP 1319
Query: 3132 AMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLTAET-IDSVPTLTTASE 3189
MP S + SE +T I ++ +L + S+ + T +D+ +TT++E
Sbjct: 1320 TPAEGTSMPTSTY-----SEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTE 1373
Score = 98.2 bits (243), Expect = 2e-19
Identities = 261/1175 (22%), Positives = 416/1175 (35%), Gaps = 218/1175 (18%)
Query: 2080 SSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTE 2139
SSPT A G M ST R P S++ S + AS ST S T + +T STE
Sbjct: 2967 SSPTTAE-GTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTT--STE 3023
Query: 2140 EIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTT--DSS 2197
+ T I T SE S TS+P S TP S++ TT DS+
Sbjct: 3024 ASSSPTTAEGTG---------IPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSN 3074
Query: 2198 SPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRA 2257
SP+ T +++ T + + STY GS +S T P A
Sbjct: 3075 SPVVTSTEVSSSPTPA--------EGTSMPISTYSEGSTPLTGVPVS-----TTPVTSSA 3121
Query: 2258 SADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVL 2317
+ +LS V E + T S + P + + T + ++
Sbjct: 3122 -----ISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLV 3176
Query: 2318 EAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLP 2377
+ D S+LS T D + P+ T T+ E G P S
Sbjct: 3177 VSSED----------STLSATPVD------TSTPVTTSTEATSSTTAE--GTSIPTSTPS 3218
Query: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP-------PPPLPPP 2430
G ++S+P P S + +S P P PP P P
Sbjct: 3219 EGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSE 3278
Query: 2431 TSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKP 2490
S T +P TVAS T+ A T+ T +++ P T+ P +
Sbjct: 3279 GSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEG 3338
Query: 2491 SSIPSGLVFTHRPEPSKPP--IAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548
S+ + + F+ P S ++ PV P TT + P T++ ++ T
Sbjct: 3339 STPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSP-------TTAEGTSIPT 3391
Query: 2549 SADYKLPSP-TSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGT----PTDSSASQAI-- 2601
S+ PS T+PL+ ++P S +E + T P + T T++S+S I
Sbjct: 3392 SS----PSEGTTPLASMPVSTTPVVS---SEVNTLSTTPVDSNTLVTTSTEASSSPTIAE 3444
Query: 2602 -TSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQ 2660
TS P + S+ + S++P T P++S + +S ++TPVT S
Sbjct: 3445 GTSLPTSTTSEGSTPL----SIMPLSTT---PVASSEASTLS-TTPVDTSTPVTTSSPTN 3496
Query: 2661 AAPTSV--------------TQFLTTEVSKTEVSA----TRSTAP----SVGLSSISITI 2698
++PT+ T VS T V++ T ST P + SS +
Sbjct: 3497 SSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASS 3556
Query: 2699 PPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQI 2758
P L + + + P +G L ++ V E T ST V R
Sbjct: 3557 SPATLQVTTMRMSTPS---EGSSSLTTMLLSSTYVTSSEASTP--------STPSVDRST 3605
Query: 2759 TANEVYGKQISAVQPSIINL--SVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGA 2816
+ P +I L S S + TP+++ + T VT + + GT S +
Sbjct: 3606 PVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEA-----GTASTLPV 3660
Query: 2817 EHAMTTPLQLTTSKHAEPPYRIPSDQVFPIAREEAPINLSLGTPAHAVTLAITKPVTVPP 2876
+ +TP+ +T + P P PI TP+ T T PV+
Sbjct: 3661 D--TSTPVITSTQVSSSPV--TPEGTTMPI-----------WTPSEGSTPLTTMPVSTTR 3705
Query: 2877 VGVTNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDEKPVDLTAGR 2936
V + G T ST S +T V ++T++ + T+D +T SV P++++
Sbjct: 3706 VTSSEGSTLSTPSV-VTSTPVT--TSTEAISSSATLDSTTMSV-------SMPMEISTLG 3755
Query: 2937 RAVCCDVVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSD 2996
+ P T PE PS+
Sbjct: 3756 TTILVSTT-------------PVTRFPESS------------------------TPSIPS 3778
Query: 2997 TNLAEAGHFFYKSKNAFDYSEGTDTAVDLTSGRVTTGEVMDYSSKTTGPYPETRQVISGA 3056
Y S + SEG+ + L TT + S ++T T +IS
Sbjct: 3779 V---------YTSMSMTTASEGSSSPTTLEG--TTTMPMSTTSERST---LLTTVLISPI 3824
Query: 3057 GISTPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVR 3116
+ +P ++ TPP +L S+ +S A T +IT++ + +T
Sbjct: 3825 SVMSPSEASTLSTPPGDTST---PLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTL-- 3879
Query: 3117 DLSGIHTADAVTSLP--AMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMESLT 3174
+ + TS P ++ + P+ S T + + S+ IT S
Sbjct: 3880 ----LVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTP 3935
Query: 3175 AETI--DSVPTLTTASEVFPEVVGDESALLIVPEE 3207
TI S P ++ ++VFP G S +I E
Sbjct: 3936 GTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTE 3970
Score = 96.7 bits (239), Expect = 5e-19
Identities = 260/1229 (21%), Positives = 425/1229 (34%), Gaps = 179/1229 (14%)
Query: 2080 SSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTD----STSSATLSIPDVKITQH 2135
S P P + +++ MP AS +S LS + +TS+ T S P
Sbjct: 2622 SMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSS 2681
Query: 2136 FSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTT- 2194
T E T T I + +L SE S +T+ + TP TS+ +S T
Sbjct: 2682 MPTST-PGERSTPLTN-----ILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTT 2735
Query: 2195 ------------DSSSPITTL---------DSITTVYTEPVDMITKFEDSEEISSSTYFP 2233
D S+P+T++ +TV T VD S E SSS
Sbjct: 2736 AEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSS---- 2791
Query: 2234 GSIIDYPEEISV-SLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTD 2292
P V S+ + P + + ++ + +ASS ++ P DT ST
Sbjct: 2792 ------PTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTP----VDT-STP 2840
Query: 2293 LLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSET-VFDHPPSSVIALP 2351
+ S K + T GI++ + A L T +S T V S++ P
Sbjct: 2841 VTTSTK---ASSSPTTAEGIVVPISTASEGSTLL----TSIPVSTTPVASSEASTLSTTP 2893
Query: 2352 MKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP 2411
+ + T T G + + +P +PS S P +S+ +S P
Sbjct: 2894 VDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPL--------TSILVSTVPVAGSEA 2945
Query: 2412 PPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSN 2471
P P S PT + +++P TPL + A ++
Sbjct: 2946 STLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEAS 3005
Query: 2472 GLPVTRICTTAPPPVPPKPSSIPS-----GLVFTHRPEPSKP----PIAPKPV-IPQLPT 2521
L T T+ P + SS P+ G+ + E S P P++ PV IP+ T
Sbjct: 3006 TLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEAST 3065
Query: 2522 TTQKPTDIH-PKPTGLSLTSSMT------LNLVTSADYKLPSPTSPLS--PHSNKSSPRF 2572
+ P D + P T ++SS T + + T ++ P P+S P ++ +
Sbjct: 3066 LSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTL 3125
Query: 2573 SKSLTETYVVITLPSEP-GTPTDSSASQAITSWPLGSPSKD--------------LVSVE 2617
S + +T +T +E +PT S TS P +PS+ + S +
Sbjct: 3126 STTPVDTSTPVTTSTEAHSSPTTSEG----TSMPTSTPSEGSTPLTYMPVSTMLVVSSED 3181
Query: 2618 PVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSS----FQAAPTSVTQFLTTE 2673
S P T+ + S+E T S ++ P + PS + P S T ++E
Sbjct: 3182 STLSATPVDTSTPVTTSTEAT---SSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSE 3238
Query: 2674 VSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTV 2733
S + S P +S + P ++ P +G L + TV
Sbjct: 3239 ASILSTTPVDSNTPLT--TSTEASSSPPTAEGTSMPTSTPS---EGSTPLTSMPVSTTTV 3293
Query: 2734 PKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTSSIVTP------ 2787
E T LS + D +T + + S S TP
Sbjct: 3294 ASSETST------LSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSF 3347
Query: 2788 -----VSLATETVTFVTCTASASYTTGTESLVGAEHAMTTPLQLTTSKHAEPPYRIPSDQ 2842
VS T++ S TT TE+ + A T + ++ P
Sbjct: 3348 STTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVS 3407
Query: 2843 VFPIAREEAPINLSLGTPAHAVTLAI--TKPVTVPPVGVTNGWTDSTVSQGITDGEVVDL 2900
P+ E +N TP + TL T+ + P + ST S+G T ++ L
Sbjct: 3408 TTPVVSSE--VNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPL 3465
Query: 2901 STTK--------------SHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVCCDVVYK 2946
STT T VT T+S T P TAG + +
Sbjct: 3466 STTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTS-TAGEGST---PLTN 3521
Query: 2947 LPFGRSCTAQQPATTL---PEDRFGYRDDHYQYDRSGP----YGYRGIGGMKPSMSDTNL 2999
+P + A A+TL P D + Q S R + S S T +
Sbjct: 3522 MPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTM 3581
Query: 3000 AEAGHFFYKSKNAFDYSEGTDTAVDLT-----SGRVTTGEVMDYSSKTTGPY--PETRQV 3052
+ + S+ + + D + +T + T EV+ T P T
Sbjct: 3582 LLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMP 3641
Query: 3053 ISGAGISTPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSS----VATPTPSTFAITTQPG 3108
+S ++ + TA P + S SS+ V + TP+ + +TT P
Sbjct: 3642 VSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPV 3701
Query: 3109 SIFSTTVRDLSGIHTADAVTSLPAMHHSQPMPRSYFI--TTGASETDIAVTGIDISASLQ 3166
S T + S + T VTS P ++ + S + TT + + ++ + + +
Sbjct: 3702 STTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVS 3761
Query: 3167 TITMESLTAETIDSVP------TLTTASE 3189
T + + S+P ++TTASE
Sbjct: 3762 TTPVTRFPESSTPSIPSVYTSMSMTTASE 3790
Score = 92.4 bits (228), Expect = 1e-17
Identities = 195/890 (21%), Positives = 317/890 (35%), Gaps = 168/890 (18%)
Query: 2077 TPGSSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASL-TDSTSSATLSIPDVKITQH 2135
TP S + + +++ +ASL+ + G S+ T S S T + + ++
Sbjct: 3350 TPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVS-- 3407
Query: 2136 FSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTD 2195
+T + E T T + +L+ T +E S S T + P+ T+S S +
Sbjct: 3408 -TTPVVSSEVNTLSTTPVDS----NTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSI 3462
Query: 2196 ---SSSPITTLDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISV-SLDRTA 2251
S++P+ + ++ +T+ T PVD T S +SS P V S+ +
Sbjct: 3463 MPLSTTPVASSEA-STLSTTPVDTSTPVTTSSPTNSS----------PTTAEVTSMPTST 3511
Query: 2252 PPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNG 2311
+G ++ +S + +ASS A T+ST + S ++ +
Sbjct: 3512 AGEGSTPLTNMPVSTTPVASS------------EASTLSTTPVDSNTFVTSSSQASSSPA 3559
Query: 2312 IILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEK 2371
+ E + T LS T +S + P ++ ST TS ++
Sbjct: 3560 TLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDR-STPVTTSTQSNSTPT 3618
Query: 2372 PAS--QLPSGSPSVSSLPAKPRPFFRSS----------------------SLDISAQPPP 2407
P LP +PS S P P +S S +S+ P
Sbjct: 3619 PPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVT 3678
Query: 2408 PPPPPPPPPPPPPPPPPPPLPPP-----TSPKPTILPKKKLTVASPVTTATPLFDAVTTL 2462
P P P P P TS + + L + ++PVTT+T + TL
Sbjct: 3679 PEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATL 3738
Query: 2463 ETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTT 2522
++T + S + ++ + TT P T PE S P I + T
Sbjct: 3739 DSTTMSVSMPMEISTLGTTILVSTTP----------VTRFPESSTPSIPSVYTSMSMTTA 3788
Query: 2523 TQ---KPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTET 2579
++ PT + T T+S L+T+ L SP S +SP +E
Sbjct: 3789 SEGSSSPTTLEGTTTMPMSTTSERSTLLTTV---LISPISVMSP-------------SEA 3832
Query: 2580 YVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTF 2639
+ T P + TP +TS GS FS+ VT + I I+SE++
Sbjct: 3833 STLSTPPGDTSTP-------LLTSTKAGS-----------FSIPAEVTTIRISITSERST 3874
Query: 2640 YISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIP 2699
++ L T P+SF A + T L T + T + T ST ++IS+++
Sbjct: 3875 PLTTLL-----VSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVI 3929
Query: 2700 PEPLALDNIHLEKPQYKEDGKLQLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQIT 2759
E G I + + P V T D A+T V +
Sbjct: 3930 TEG-------------------STPGTTIFIPSTP-VTSSTADV---FPATTGAVSTPVI 3966
Query: 2760 ANEVYGKQISAVQPSIINLSVTSSIVTPVSLATETVTFVT--------------CTASAS 2805
+ ++ + + S T TP +T+VT CT SAS
Sbjct: 3967 TSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSAS 4026
Query: 2806 YTTGTESLVGAEHAMTTPLQLTTSKHAEPPYRIPSDQV---FPIAREEAPINLSLGT--- 2859
+ T + + T P +T S + P I S + FP A P S +
Sbjct: 4027 TLSATSTPHTSTSVTTRP--VTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTV 4084
Query: 2860 -PAHAVTLAI-TKPVT----VPPVGVTNGWTDSTVSQGITDGEVVDLSTT 2903
P T+ TKP T P V T T++T+ T V +TT
Sbjct: 4085 NPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTT 4134
Score = 84.7 bits (208), Expect = 2e-15
Identities = 298/1428 (20%), Positives = 436/1428 (30%), Gaps = 228/1428 (15%)
Query: 178 LISDSEASQEETTKKQK----VVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL-QQ 232
L+++SE S TT E P PP + P G PL +
Sbjct: 2290 LVANSEVSTLSTTPVDSNTPFTTSTEASSP-----PPTAEGTSMPT-STSSEGNTPLTRM 2343
Query: 233 DGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ---TPQT-DHAKLPLQR--DASRPQTKQA 286
+ ++S + + + P T P+ +Q +P T D +P + S P T
Sbjct: 2344 PVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTS-V 2402
Query: 287 DIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP 346
+ V + S P+ TP + + G + P + PS T PLA P
Sbjct: 2403 PVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMP 2462
Query: 347 GTVKPPVQ---------PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV 397
+ P V P T+ P + P P S L V
Sbjct: 2463 VSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPV 2522
Query: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
TP P + T V + P+ + S A + T P
Sbjct: 2523 STTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMP----------------- 2565
Query: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPA 517
TS G T P + P P A S P T P
Sbjct: 2566 -TSTYSEGST-------------PLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTET 2611
Query: 518 KPSPQQPGSTKPPSQQPGSAKPS------AQQPSPAKPSAQQSTKPVS-----QTGSGKP 566
SP T P P S + P + ++ ST PV T +G
Sbjct: 2612 SSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTS 2671
Query: 567 LQPPTVSPSAKQPPSQGLPKTICPLCN---TTELLLHVPEKANFNTCTECQTTVCSLCGF 623
P T S+ + G T PL N +T LL + T + T V +
Sbjct: 2672 SSPTTAEGSSMPTSTPGERST--PLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEA 2729
Query: 624 NPNPHLTEVKEWLCLNCQMKRALGGD-----------LAPVPSSPQPKLKTAPV-----T 667
+ +P E M+ + D PV SS + T V
Sbjct: 2730 SSSPTTAE-------GTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPV 2782
Query: 668 TTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEAD 727
TTS + SSP + + + P + + PL P H +P A + EA
Sbjct: 2783 TTSTEASSSPTTAEVTSMPTSTPSETST---------PLTSMPVNH-TPVASS----EAG 2828
Query: 728 SLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI--PSSKVQS 785
+LS P + S P TT +SSS TT I P S
Sbjct: 2829 TLS--TTPVDTSTP--------------------VTTSTKASSSPTTAEGIVVPISTASE 2866
Query: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ 845
+ T+ P+ T P S + +P D+ +IP S G SS + +
Sbjct: 2867 GSTLLTSIPVST---TPVASSEASTLSTTPVDT-SIPVTTSTE------GSSSPTTAEGT 2916
Query: 846 VDPVQKKEEPKKAQTK--MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSR 903
P+ E T +S P A G + T P ++P
Sbjct: 2917 SMPISTPSEVSTPLTSILVSTVPVA-----------GSEASTLSTTPVDTRTPVTTSAEA 2965
Query: 904 RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963
S T P S P + +T S+AS L T P S P
Sbjct: 2966 SSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRT-----PADTSTPVTT 3020
Query: 964 MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKA-PAAEKLE--PKAEQAPTVKR 1020
+A + G P ST P SIPV A P A L P +P V
Sbjct: 3021 STEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTS 3080
Query: 1021 TETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPN----F 1076
TE P P + T+ P + P ST P+ + ++ S P +
Sbjct: 3081 TEVSSSPTPAEG----TSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPV 3136
Query: 1077 NTCTECKNQVCNLCGFN-PTPHLTEIQEWLC-LNCQTQRAISGQLGDIRKMPPAPSGPKA 1134
T TE + G + PT +E L + T +S + + P S P
Sbjct: 3137 TTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVT 3196
Query: 1135 SPMPVPTESSSQKTAVP---PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTT 1191
+ + ++++ T++P P + V + T ++ P+ T+
Sbjct: 3197 TSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTS 3256
Query: 1192 DQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPE 1251
E + E +P SE PL T
Sbjct: 3257 --------TEASSSPPTAEGTSMPTSTP---------SEGSTPLTSMPVSTTTVASSETS 3299
Query: 1252 AKTSAPEEQKHDLLK-SQVQIAEEKLEGRVAP-KTVQEGKQPQTKMEGLPSGTPQSLPKE 1309
++ P + + SQ + +G P T EG P T M S TP
Sbjct: 3300 TLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSF--STTPVV---- 3353
Query: 1310 DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDG 1369
T+ P T E T E TSS + +P L+ S+
Sbjct: 3354 -SSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTP--LASMPVSTTP 3410
Query: 1370 ISSSLGEIPSLIPTDEKDILKGLKKDSFSQ--ESSPSSPSDLAKLESTVLSIL------- 1420
+ SS S P D ++ + S S S P+ ST LSI+
Sbjct: 3411 VVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPV 3470
Query: 1421 -EAQASTLADEKSEKKTQPHEVSP--EQPKDQEKTQSLSET--------LEITISEEEIK 1469
++ASTL+ + T SP P E T + T + +S +
Sbjct: 3471 ASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVA 3530
Query: 1470 ESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESS 1517
S+ T DS + SS S +TT R S SS
Sbjct: 3531 SSEASTLSTTPVDSNTFVTSS-SQASSSPATLQVTTMRMSTPSEGSSS 3577
Score = 80.9 bits (198), Expect = 3e-14
Identities = 311/1587 (19%), Positives = 486/1587 (30%), Gaps = 221/1587 (13%)
Query: 33 SHTAIPAGMEADLSQLSEEERRQIAAVMSRAQ----GLPKGSVPPAAAESPSMHR----- 83
S T + EA S + E+ + S +P + P A++E+ ++
Sbjct: 420 SKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDS 479
Query: 84 ------KQELDSSHPPKQSGRPPD--PGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISL 135
E SS P + P P + P S S +T S + + ST +
Sbjct: 480 KTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSE---ASTLSTTPV 536
Query: 136 KESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFD--LISDSEASQEETTKKQ 193
S T E SS P S + + S P L+ SEAS TT
Sbjct: 537 DTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPAD 596
Query: 194 KVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG 253
E + P G + ++S + + + P
Sbjct: 597 SNTFVTTSS-EASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVD 655
Query: 254 TGKPIQGPTQTPQT----DHAKLPLQR--DASRPQTKQADIVRGESVKPSLPSP-SKPPI 306
+ P+ T+ + + +P + S P T V V S S S P+
Sbjct: 656 SNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMP--VNTTLVASSEASTLSTTPV 713
Query: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366
TP + + G + P + PS + PL P + K + + PL
Sbjct: 714 DTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVS-KTLLTSSEASTLSTTPL 772
Query: 367 GPAK----------PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416
+ P G+ P S L V TP P + T V
Sbjct: 773 DTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVD 832
Query: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476
+ P+ + S T P G+ P P T+ T S P
Sbjct: 833 SNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSM-PVSTTLVATSAISTLSTTPVD 891
Query: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536
P A+ P P+ PG + P P ST P
Sbjct: 892 TSTPVTNSTEARSSPTTSEGTSMPTSTPGEG---------STPLTSMPDSTTPVVSS--E 940
Query: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTE 596
A+ + P ST+ S + + PT +PS P P + + N+
Sbjct: 941 ARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEA 1000
Query: 597 LLLH---VPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV 653
L V T TE + + G + + +
Sbjct: 1001 STLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETS 1060
Query: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
S P + PVTT S S SS TS P S+ P P+ + +
Sbjct: 1061 TLSTTPADTSTPVTTYSQASSSSTTADGTS-----MPTSTYSEGSTPLTSVPVSTRLVVS 1115
Query: 714 GSPSAKAKQPPEA--------DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTD 765
S + P + ++ S P + S+P+ +P ++ M TT
Sbjct: 1116 SEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPT----SPPSEGTTPLASMPVSTTL 1171
Query: 766 LVSSSSAT--TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI-- 821
+VSS + T T P ++V + E + PP ++ P+ + GE+ +P S +
Sbjct: 1172 VVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTST---PGERSTPLTSMPVRH 1228
Query: 822 --------------PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867
P S S SS + + P E T +
Sbjct: 1229 TPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTT 1288
Query: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQ--QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQE 925
P+ S P T G V + + SP P E + S+ + S+ TP
Sbjct: 1289 LVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGT--------SMPTSTYSEGRTPLT 1340
Query: 926 TVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP--PKST 983
++ + S A +++ST P S P +A S P TS+G P S
Sbjct: 1341 SIPVNT----TLVASSAISILSTT----PVDNSTPVTTSTEAC--SSPTTSEGTSMPNSN 1390
Query: 984 GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKA 1043
P SIPV P V + P+ S T +
Sbjct: 1391 PSEGTTPLTSIPVST----------------TPVVSSEASTLSATPVDTSTPGTTSAEAT 1434
Query: 1044 VLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQE 1103
PT E P ST KT L K P NT N + P + +
Sbjct: 1435 SSPTTAEGISIPTSTPSEGKTPL----KSIPVSNT--PVANSEASTLSTTPVDSNSPVV- 1487
Query: 1104 WLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQE 1163
T A+S P P+ + + P+E S+ T++P V E
Sbjct: 1488 -------TSTAVSSS--------PTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSE-- 1530
Query: 1164 VKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPE 1223
+ + T ++ P VTT + S D S
Sbjct: 1531 ---------INSLSTTPAVTSTP--VTTYSQASSSPTTADGTSM---------------- 1563
Query: 1224 EEKIRSEEKKPLLEEKKPTPEDKKLLPEAKT--SAPEEQKHDLLKSQVQIAEEKLEGRVA 1281
+ SE PL P + EA T + P + K + S + EG +
Sbjct: 1564 QTSTYSEGSTPL--TSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEG--S 1619
Query: 1282 PKTVQEGKQPQTKMEGLP-SGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTE 1340
T+ + + +P S TP + P+ +T + + P T+ E T
Sbjct: 1620 SMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPV-DSNSPVITS----TEVSSSPTP 1674
Query: 1341 KEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQE 1400
E TS+ + ++P L+ + ++SS S P D + S
Sbjct: 1675 AEGTSMPTSTYTEGRTP--LTSITVRTTPVASSAISTLSTTPVDNSTPV----TTSTEAR 1728
Query: 1401 SSPSSPSDLAKLEST-------VLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQ 1453
SSP++ + ST + SI + L+ E S P + S E T
Sbjct: 1729 SSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATS 1788
Query: 1454 SLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSV 1513
S + +I + E T P S SE TT + V
Sbjct: 1789 SPTTAEGTSIPTSTLSEGMTPLTST---------PVSHTLVANSEASTLSTTPVDSNSPV 1839
Query: 1514 EESSESENSPVPQRKRRTSVGSSSSDE 1540
S+ +SP P TS+ +S+ E
Sbjct: 1840 VTSTAVSSSPTP--AEGTSIATSTPSE 1864
Score = 80.5 bits (197), Expect = 4e-14
Identities = 270/1347 (20%), Positives = 424/1347 (31%), Gaps = 186/1347 (13%)
Query: 305 PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK-------------- 350
P++ TP AQ + GP+ + PSG + PL + P +V
Sbjct: 240 PVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTP 299
Query: 351 -----PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG---PKALAQPPGVGKTPA 402
P + + P G + P + T P + P P A ++ + TP
Sbjct: 300 AATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPV 359
Query: 403 Q-------QPGPAKPPTQQVGT----------PKPLAQQPG---LQSPAKAPGPTKTPVQ 442
P+ PT T PL P L + ++A + PV
Sbjct: 360 DTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVD 419
Query: 443 QPGPGKIPAQQAGPGKTSAQQTG-PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP-- 499
A +A T+A+ T T PS+ P P P S P
Sbjct: 420 SK-TFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVD 478
Query: 500 -----PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ-----PGSAKPSAQQPSPAKP 549
+ S+ PP + S GST S S++ S +P
Sbjct: 479 SKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDT 538
Query: 550 SAQQSTKPVSQTGSGKP--LQPPTVSPSAKQPPSQGLP-KTICPLCNTTELLLHVPEKAN 606
S +T + + S P PT +PS P +P T + + P +N
Sbjct: 539 STPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSN 598
Query: 607 --FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA 664
T +E ++ + G + + + + L S P
Sbjct: 599 TFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNT 658
Query: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
PVTT++ + SS + TS P ++ P P+ TL S A
Sbjct: 659 PVTTSTEATSSSTTAEGTS-----MPTSTYTEGSTPLTSMPV--NTTLVASSEASTLSTT 711
Query: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
D+ S P + +E +P D P +T S+ T+ P +
Sbjct: 712 PVDT-STPV-----TTSTEASSSPTTADGASMP----TSTPSEGSTPLTSMPVSKTLLTS 761
Query: 785 SQAEEKTTPPLKTD----SAKPSQSFPPTGEKVS-PFDSKAIPRPASDSKIISHPGPSSE 839
S+A +T PL T ++ + P T E S P + + P S +S +S
Sbjct: 762 SEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSP 821
Query: 840 SKGQKQVDPVQKKEEPKKAQTKMSPKP---DAKPMPKGS----PTPPGPRPTAG------ 886
PV P T++S P + MP + TP P +
Sbjct: 822 EASTLSTTPVD-SNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATS 880
Query: 887 -----QTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQ 941
T P +P R S T P S P +T + S+
Sbjct: 881 AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSE 940
Query: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP--PKSTGQAPPAPAKSIPVKKE 999
A L +T P S P + A S P T++G P ST P S PV
Sbjct: 941 ARTLSAT-----PVDTSTPVTTSTE--ATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHT 993
Query: 1000 TKA---PAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056
A + P P TE PP + + T+ P + P + P
Sbjct: 994 LVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPL----TRMPV 1049
Query: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLC-----GFNPTPHLTEIQEWL-CLNCQ 1110
ST + +E + S P + +T +Q + PT +E L +
Sbjct: 1050 STTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVS 1109
Query: 1111 TQRAISGQLGDIRKMP-----PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVK 1165
T+ +S + + P P + +AS P E +S T+ PP V
Sbjct: 1110 TRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTS-PPSEGTTPLASMPVS 1168
Query: 1166 TEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEE 1225
T +++ TLS + K + + E P ++
Sbjct: 1169 T---TLVVSSEANTLSTTPVD--------------SKTQVATSTEASSPPPTAEVTSMPT 1211
Query: 1226 KIRSEEKKPLLE-EKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAP-K 1283
E PL + TP TS + ++ + EG P
Sbjct: 1212 STPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTS 1271
Query: 1284 TVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKED 1343
T EG T + +P T E T + P T+ E T E
Sbjct: 1272 TTSEG---STLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSN----EVSSSPTPAEG 1324
Query: 1344 DKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSP 1403
TS+ + ++P L+ ++ ++SS I S P D + + S +S
Sbjct: 1325 TSMPTSTYSEGRTP--LTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSE 1382
Query: 1404 ------SSPSD----LAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQ 1453
S+PS+ L + + ++ ++ASTL+ P + S E T
Sbjct: 1383 GTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLS-------ATPVDTSTPGTTSAEATS 1435
Query: 1454 SLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSV 1513
S + I+I E K + IP S SE TT + V
Sbjct: 1436 SPTTAEGISIPTSTPSEG---------KTPLKSIPVSNTPVANSEASTLSTTPVDSNSPV 1486
Query: 1514 EESSESENSPVPQRKRRTSVGSSSSDE 1540
S+ +SP P TS+ S+ E
Sbjct: 1487 VTSTAVSSSPTP--AEGTSIAISTPSE 1511
Score = 76.3 bits (186), Expect = 8e-13
Identities = 256/1318 (19%), Positives = 412/1318 (31%), Gaps = 161/1318 (12%)
Query: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP 361
S P+ TP + + G + P + PS T PL P + P V +T
Sbjct: 1358 STTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTL- 1416
Query: 362 PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP---------- 411
A P+ + P + + G P GKTP + + P
Sbjct: 1417 SATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLS 1476
Query: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
T V + P+ + S T + P G A + P T+ + S
Sbjct: 1477 TTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGS-TALTSIPVSTTTVASSEINSLS 1535
Query: 472 QLPGPAKPPPQQPGPA-KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530
P P A P G++ S + P P +T
Sbjct: 1536 TTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLST 1595
Query: 531 SQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP 590
+ + +A + + +A+ S+ +S G PL T P + P + T+
Sbjct: 1596 TPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLL--TSIPVSTTPVASPEASTL-- 1651
Query: 591 LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN-PNPHLTEVKEWLCLNCQMKRALGGD 649
+TT V + T TE ++ G + P TE + L ++
Sbjct: 1652 --STTP----VDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPL-------TSITVR 1698
Query: 650 LAPVPSSPQPKLKTAPV-----TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP 704
PV SS L T PV TTS ++SSP T+ + + P S+ P
Sbjct: 1699 TTPVASSAISTLSTTPVDNSTPVTTSTEARSSP----TTSEGTSMPNSTPSEGTTPLTSI 1754
Query: 705 PLVKQPTLHGSPSAKAKQP--------PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ 756
P+ P L S + P ++ S P + S+P+ + P
Sbjct: 1755 PVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMT---PLT 1811
Query: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
V T LV++S A+T P + P+ T +A S P G ++
Sbjct: 1812 STPVSHT--LVANSEASTLSTTPVD---------SNSPVVTSTAVSSSPTPAEGTSIATS 1860
Query: 817 DSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSP-KPDAKPMPKGS 875
+ + + SSE+ V AQ SP D MP +
Sbjct: 1861 TPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTST 1920
Query: 876 PTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSIT--DAPKSQPTTPQET------- 926
P P T+ T S + S + +T S PTT T
Sbjct: 1921 PREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAY 1980
Query: 927 ------VTGKLFGFGASIFSQASNLIST---AGQPGPHSQSGPGAPMK------QAPAPS 971
+T + S+AS L +T P S G +P Q PS
Sbjct: 1981 SEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPS 2040
Query: 972 QPPTS-QGPPKSTGQAPPAPAKSI---PVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP 1027
+ T G P ST + ++ PV +T+ + + A + +
Sbjct: 2041 ERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEG 2100
Query: 1028 PPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVC 1087
P+ S L+ P + + L +P ++ + TE + S P T +
Sbjct: 2101 SPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTE--VSSSPIPTEGTSMQTSTYSD 2158
Query: 1088 NLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKAS-----PMPVPTE 1142
P T + ++ + + + A S P S P P+E
Sbjct: 2159 RRTPLTSMPVSTTVVASSAISTLSTTPVDTST-PVTNSTEARSSPTTSEGTSMPTSTPSE 2217
Query: 1143 SSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEK 1202
S+ T++P V + E T + + T S E T + +
Sbjct: 2218 GSTPFTSMP--VSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLS 2275
Query: 1203 DKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKH 1262
+ + L +P L+ E + TP D T A
Sbjct: 2276 EGTTPLTS---IPVSHTLVANSE----------VSTLSTTPVDSNTPFTTSTEASS---- 2318
Query: 1263 DLLKSQVQIAEEKLEGRVAP-KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQP 1321
EG P T EG P T+M P S T T+ P
Sbjct: 2319 ---------PPPTAEGTSMPTSTSSEGNTPLTRM-------PVSTTMVASFETSTLSTTP 2362
Query: 1322 QPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLI 1381
T + G T +D TS+ + +P L+ S+ + SS S
Sbjct: 2363 ADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTP--LTSVPVSTMPVVSSEASTHSTT 2420
Query: 1382 PTDEKDILKGLKKDSFSQ-----ESSPSSP-----SDLAKLESTVLSILEAQASTLADEK 1431
P D + + S S S P+SP + LA + + ++ ++A TL+
Sbjct: 2421 PVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTP 2480
Query: 1432 SEKKTQPHEVSPE---QPKDQE------KTQSLSETL--EITISEEEIKESQEERKDTFK 1480
+ T P S E P E T S TL I +S + + T
Sbjct: 2481 VDTST-PMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTP 2539
Query: 1481 KDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSS 1538
DS + +S + + + + Y E S+ + PV + +S S+ S
Sbjct: 2540 VDSNSPVVTSTEISSSATSAEGTSMPTSTYS--EGSTPLRSMPVSTKPLASSEASTLS 2595
Score = 73.9 bits (180), Expect = 4e-12
Identities = 258/1301 (19%), Positives = 403/1301 (30%), Gaps = 176/1301 (13%)
Query: 218 PIPKQQGPGRDPLQQDGTPKSIS--SQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ 275
P+ P DGT S S+ + S P T + T T Q
Sbjct: 1544 PVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQ 1603
Query: 276 RDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQP 335
AS + + G S+ S PS P + P + P + P
Sbjct: 1604 VTAST-EASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPV-------ASPEASTLSTTP 1655
Query: 336 SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
P+ P GT+ P + P T P + L+ P
Sbjct: 1656 VDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASS-AISTLSTTP 1714
Query: 396 GVGKTPAQQPGPAKP-PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI---PA 451
TP A+ PT GT P + +P + + TPV + P
Sbjct: 1715 VDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPI 1774
Query: 452 QQAGPGKTSAQQT-------GPTKPPSQLPGPAKPPPQQP--------GPAKPPPQQPGS 496
+ P TS + T G + P S L P P A P
Sbjct: 1775 DTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVD 1834
Query: 497 AKPP--SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS-----QQPGSAKPSAQQPSPAKP 549
+ P + S+ P P + S GST S S++ + +PA
Sbjct: 1835 SNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVT 1894
Query: 550 S------AQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPE 603
S AQ S+ P + GS P T +P +PP +P + + ++ L
Sbjct: 1895 STPVTTYAQVSSSPTTADGSSMP----TSTPREGRPPLTSIPVSTTTVASSEINTLST-- 1948
Query: 604 KANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP--SSPQPKL 661
T + +T V + + +P + G P P S L
Sbjct: 1949 -----TLADTRTPVTTYSQASSSPTTAD----------------GTSMPTPAYSEGSTPL 1987
Query: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721
+ P++TT VS S T+P + P ++ PT G S +
Sbjct: 1988 TSMPLSTTLVVS-SEASTLSTTPVDTSTPATTSTEGSS---------SPTTAGGTSIQTS 2037
Query: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS 781
P E + P V S + V T + +S+ A++ S
Sbjct: 2038 TPSERTTPLAGMPVSTTLVVSSEGNT-------LSTTPVDSKTQVTNSTEASSSATAEGS 2090
Query: 782 KVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESK 841
+ A + +P L ++ P + P + S + + S+S +I+ SS
Sbjct: 2091 SMTISAPSEGSPLL---TSIPLSTTPVASPEASTLSTTPVD---SNSPVITSTEVSSS-- 2142
Query: 842 GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQ 901
P+ + + T + MP + + T P +P
Sbjct: 2143 ------PIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNST 2196
Query: 902 SRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG 961
R S T P S P+ T + S+AS L +T P S P
Sbjct: 2197 EARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSAT-----PVDTSTPV 2251
Query: 962 APMKQAPAPSQPPTSQGP--PKSTGQAPPAPAKSIPVKKETKA---PAAEKLEPKAEQAP 1016
+ A S P T++G P ST P SIPV A + P P
Sbjct: 2252 TTSTE--ATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTP 2309
Query: 1017 TVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNF 1076
TE PP + + T+ + P + P ST + E + S P +
Sbjct: 2310 FTTSTEASSPPPTAEGTSMPTSTSSEGNTPL----TRMPVSTTMVASFETSTLSTTPADT 2365
Query: 1077 NTCTECKNQVCNLCGFNPT-------PHLTEIQEWLCLN---CQTQRAISGQLGDIRKMP 1126
+T +Q G +PT P T + L T +S + P
Sbjct: 2366 STPVTTYSQ----AGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTP 2421
Query: 1127 -----PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS 1181
P + +AS P E +S T+ PP V T T
Sbjct: 2422 VDTSTPVTTSTEASSSPTTAEGTSIPTS-PPSEGTTPLASMPVSTTPVVSSEAGTLSTTP 2480
Query: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKP 1241
++ PM T+ + P E ++P I + + L P
Sbjct: 2481 VDTSTPMTTSTE---------------ASSSPTTAEDIVVP----ISTASEGSTLLTSIP 2521
Query: 1242 TPEDKKLLPEAKT--SAPEEQKHDLLKS-QVQIAEEKLEGRVAP-KTVQEGKQPQTKMEG 1297
PEA T + P + ++ S ++ + EG P T EG P +
Sbjct: 2522 VSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTP---LRS 2578
Query: 1298 LPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSP 1357
+P T + L + T T P T E T +D S+ + +
Sbjct: 2579 MPVST-KPLASSEASTLSTTPVDTSIPVTT---STETSSSPTTAKDTSMPISTPSEVST- 2633
Query: 1358 QGLSDTGYSSDGISSSLGEIPSLIPTDEKDIL---KGLKKDSFSQESSPSSPSDLAKLES 1414
L+ S+ ++SS S P D + ++ G + E S S P+ S
Sbjct: 2634 -SLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGS-SMPTSTPGERS 2691
Query: 1415 TVLSILEAQASTLAD-EKSEKKTQPHEVSPEQPKDQEKTQS 1454
T L+ + + LA+ E S T P + S E + S
Sbjct: 2692 TPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSS 2732
Score = 72.8 bits (177), Expect = 8e-12
Identities = 185/857 (21%), Positives = 299/857 (34%), Gaps = 149/857 (17%)
Query: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
S + S +P VSS P +S + P P P P+ P+
Sbjct: 96 SSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEE 155
Query: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493
+ T+A T P F+A T+L + + P+T + P P+ ++I
Sbjct: 156 SISS------TMAFVSTAPLPSFEAYTSLTYKVDMST---PLTTSTQASSSPTTPESTTI 206
Query: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD---IHPKPTGLSLTSSMTLNLVTSA 2550
P E S P + +P +T K I T + +++ +T++ S+
Sbjct: 207 PKST----NSEGSTP-------LTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASS 255
Query: 2551 DYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLG--- 2607
SPT+ P + S+P S S +T PL
Sbjct: 256 -----SPTTAEGPSLSNSAP------------------------SGGSTPLTRMPLSVML 286
Query: 2608 --SPSKDLVSVEPVFSVVPPVTAVEI---PISSEQTFYISGALQTFSATPVTA-PSSFQA 2661
S +S P + +P +T+ E P ++E T I + T +TP+T+ P+S
Sbjct: 287 VVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTS-IPTSTYTEGSTPLTSTPASTMP 345
Query: 2662 APTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKL 2721
TS L+ T T ST PS S+ T + + +G
Sbjct: 346 VATSEMSTLSITPVDTSTLVTTSTEPS----SLPTTAEATSMLTSTL--------SEGST 393
Query: 2722 QLVGDVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQ--ISAVQPSIINLS 2779
L + V E TT S + + + +++ + I+ PS +
Sbjct: 394 PLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTP 453
Query: 2780 VTSSIVTPVSLATETVTFVTCT---ASASYTTGTESLVGAEHAMTTPLQLTTSKHAEPPY 2836
+TS V+ +A+ + ++ T + TT TE+ A + +T P
Sbjct: 454 LTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPL 513
Query: 2837 RIPSDQVFPIAREEA------PINLSLGTPAHAVTLAITKPVTVPPVGVTNGWTDSTVSQ 2890
S P+A EA P++ S TP + A + T + ST S+
Sbjct: 514 TSMSVSTMPVASSEASTLSTTPVDTS--TPVTTSSEASSSSTTPEGTSIPT----STPSE 567
Query: 2891 GITDGEVVDLSTTKSHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVCCDVVYKLPFG 2950
G T + +ST R VV+ + ST+S D T+ +
Sbjct: 568 GSTPLTNMPVST----RLVVSSEASTTSTTPA---DSNTFVTTSSEAS-----------S 609
Query: 2951 RSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLAEAGHFFYKSK 3010
S TA+ T++P + Y RG S+S T L + S
Sbjct: 610 SSTTAE--GTSMP---------------TSTYSERGTTITSMSVS-TTLVASSEASTLST 651
Query: 3011 NAFDYSEGTDTAVDLTSGRVTT-GEVMDYSSKTTGPYPETRQVISGAGISTPQYSTARMT 3069
D + T+ + TS T G M S+ T G P T ++ +++ + ST T
Sbjct: 652 TPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTT 711
Query: 3070 PPPGPQYCVGSVLRSSNGVVYSSVATPTP--------------STFAITTQPGSIFSTTV 3115
P S SS+ + PT S +T+ S STT
Sbjct: 712 PVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTP 771
Query: 3116 RDLS-GIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTGIDISASLQTITMES-L 3173
D S I T+ + P MP S SE +T I +S + T S L
Sbjct: 772 LDTSTHITTSTEASCSPTTTEGTSMPIS-----TPSEGSPLLTSIPVSITPVTSPEASTL 826
Query: 3174 TAETIDSVPTLTTASEV 3190
+ +DS +TT++EV
Sbjct: 827 STTPVDSNSPVTTSTEV 843
Score = 68.6 bits (166), Expect = 2e-10
Identities = 184/911 (20%), Positives = 288/911 (31%), Gaps = 143/911 (15%)
Query: 232 QDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIV-- 289
+ TP + + S GT T TP T K +S P T + +V
Sbjct: 2807 ETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKA-----SSSPTTAEGIVVPI 2861
Query: 290 ----RGESVKPSLPSPSKP------------PIQQPTPGKPPAQQPGHEKSQPGPAKPPA 333
G ++ S+P + P P+ P + + G + P +
Sbjct: 2862 STASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPIS 2921
Query: 334 QPSGLTKPLAQQPGTVKP---------PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE 384
PS ++ PL + P P T P + P G+ P S
Sbjct: 2922 TPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPIST 2981
Query: 385 QPG--------------PKALAQPPGVGKTPAQQPGP-------AKPPTQQVGTPKPLAQ 423
PG P A ++ + +TPA P + PT GT P++
Sbjct: 2982 -PGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPIST 3040
Query: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP---- 479
+P + + TPV P + T + P+ G + P
Sbjct: 3041 PSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTY 3100
Query: 480 ----PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535
P P P + S P T P A SP T P+ P
Sbjct: 3101 SEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPS 3160
Query: 536 -SAKPSAQQP--SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA---------KQPPSQG 583
+ P P + S++ ST + + P+ T + S+ PS+G
Sbjct: 3161 EGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEG 3220
Query: 584 L-PKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQM 642
+ P T P+ NT + ++ S + N LT E +
Sbjct: 3221 MTPLTSVPVSNT--------------PVASSEASILSTTPVDSNTPLTTSTE---ASSSP 3263
Query: 643 KRALGGDL-APVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPK 701
A G + PS L + PV+TT+ V+ S T+P + P S+A
Sbjct: 3264 PTAEGTSMPTSTPSEGSTPLTSMPVSTTT-VASSETSTLSTTPADTSTPVTTYSQA---S 3319
Query: 702 KPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761
PP+ ++ S ++ P ++S P S S PV P
Sbjct: 3320 SSPPIADGTSMPTSTYSEGSTP--LTNMSFSTTPVVSSEASTLSTTPVDTSTP------- 3370
Query: 762 PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTD-SAKPSQSFPPTGEKVSPFDSKA 820
TT +S S TT +S S E TTP S P S +P DS
Sbjct: 3371 VTTSTEASLSPTTAEG--TSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNT 3428
Query: 821 I---PRPASDSKIISH-----PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872
+ AS S I+ +SE + P+ + +S P P
Sbjct: 3429 LVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTP 3488
Query: 873 KGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQ----PTTPQETVT 928
+ +P PT + P + E S + S T S+ TTP ++ T
Sbjct: 3489 VTTSSPTNSSPTTAEVTSMPTST--AGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNT 3546
Query: 929 GKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPM---------KQAPAPSQPPTSQGP 979
AS S A+ ++T P S M +A PS P +
Sbjct: 3547 FVTSSSQAS-SSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRST 3605
Query: 980 PKST---GQAPPAPAKSIPVKKETKAPAAEKLE--PKAEQAPTVKRTETEKKPP-----P 1029
P +T + P P + I + T + + L P + + T+ T P P
Sbjct: 3606 PVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTP 3665
Query: 1030 IKDSKSLTAEP 1040
+ S +++ P
Sbjct: 3666 VITSTQVSSSP 3676
Score = 66.2 bits (160), Expect = 8e-10
Identities = 217/1080 (20%), Positives = 334/1080 (30%), Gaps = 152/1080 (14%)
Query: 89 SSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEH 148
SS S P D P TT T S S + S+ T L
Sbjct: 2411 SSEASTHSTTPVDTSTPV--------TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMP 2462
Query: 149 KSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208
S+ P SE LS ++ V+ P + + +EAS TT + VV +
Sbjct: 2463 VSTT-PVVSSEAGTLS--TTPVDTSTP--MTTSTEASSSPTTAEDIVVPISTASEGSTLL 2517
Query: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQG---PTQTP 265
IP P P + + S P ++ + +G PT T
Sbjct: 2518 TS--------IPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTY 2569
Query: 266 QTDHAKLPLQRDASRP-QTKQADIVRGESVKPSLP-SPSKPPIQQPTPGKP---PAQQPG 320
L +++P + +A + V S+P + S PT K P P
Sbjct: 2570 SEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPS 2629
Query: 321 HEKSQPGPAKPPAQP--SGLTKPLAQQP-----------GTVKPPVQPPGTTKPPAQPLG 367
+ P S L+ P GT P G++ P + P
Sbjct: 2630 EVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGE 2689
Query: 368 PAKP------PAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP- 420
+ P + + S+ P + P + P A+ + ++ TP
Sbjct: 2690 RSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDG 2749
Query: 421 --------LAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG-PTKPPS 471
++ P S A T P + +A T+A+ T PT PS
Sbjct: 2750 STPLTSILVSTLPVASSEASTVSTTAVDTSIP---VTTSTEASSSPTTAEVTSMPTSTPS 2806
Query: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ------PG 525
+ P P P A S P T P A SP P
Sbjct: 2807 ETSTPLTSMP-----VNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPI 2861
Query: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV--------SQTGSGKPLQP-----PTV 572
ST ++ P + P + ++ ST PV S GS P P
Sbjct: 2862 STASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPIS 2921
Query: 573 SPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEV 632
+PS P + + P+ + L T + +T V + + +P E
Sbjct: 2922 TPSEVSTPLTSILVSTVPVAGSEASTLST-------TPVDTRTPVTTSAEASSSPTTAEG 2974
Query: 633 KEWLCLNCQMKR----ALGGDLAPVPSSPQPKLKTAPV-----TTTSAVSKSSPQPQQ-- 681
+R ++ PV SS L P TTS + SSP +
Sbjct: 2975 TSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGT 3034
Query: 682 ----TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP-SAKAKQPPEADSLSKPAPPK 736
++P + + P L+ P P + + TL +P + + + S P P +
Sbjct: 3035 GIPISTPSEGSTP---LTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAE 3091
Query: 737 EPSVPSE---QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
S+P + P+ P P T S+ +TT D S+ V + E ++P
Sbjct: 3092 GTSMPISTYSEGSTPLTG----VPVSTTPVTSSAISTLSTTPVDT-STPVTTSTEAHSSP 3146
Query: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
++ P+ S P G + P S ++S + + PV
Sbjct: 3147 TTSEGTSMPT-STPSEGSTPLTY------MPVSTMLVVSSEDSTLSATPVDTSTPVTTST 3199
Query: 854 EPKKAQTKMSPK-PDAKPMPKGSP---TPPGPRPTAGQ------TVPTPQQSPKPQEQSR 903
E + T P + P +P P P A T P +P
Sbjct: 3200 EATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEA 3259
Query: 904 RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP 963
S T P S P+ +T S+ S L +T P S P
Sbjct: 3260 SSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTT-----PADTSTPVTT 3314
Query: 964 MKQAPAPSQPPTSQGP--PKST---GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
QA S PP + G P ST G P + + P P
Sbjct: 3315 YSQAS--SSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVT 3372
Query: 1019 KRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNT 1078
TE P + + T+ P + P + P ST P+ +E+N S P + NT
Sbjct: 3373 TSTEASLSPTTAEGTSIPTSSPSEGTTPL----ASMPVSTTPVVSSEVNTLSTTPVDSNT 3428
Score = 64.3 bits (155), Expect = 3e-09
Identities = 168/884 (19%), Positives = 257/884 (29%), Gaps = 139/884 (15%)
Query: 238 SISSQQPEKIKSQPPGTGKPI----QGPTQTPQTDHAKLPLQR--DASRPQTKQADIVRG 291
+++S + + + P T P+ Q + P D +P + S P T +
Sbjct: 3292 TVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMS-FSTT 3350
Query: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351
V + S P+ TP + + G + P + PS T PLA P + P
Sbjct: 3351 PVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTP 3410
Query: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV---GKTPAQQPGPA 408
V T P T S + SS + + P G TP +
Sbjct: 3411 VVSSEVNTLSTT----PVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLS 3466
Query: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK 468
P +P PT + +P AG G T
Sbjct: 3467 TTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGST--------- 3517
Query: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528
P + +P P + S S+ P Q + S GS+
Sbjct: 3518 PLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSS 3577
Query: 529 PPSQQPGSAKPSAQQPS-PAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ-GLPK 586
+ S ++ + S P+ PS +ST + T S PP V PS+ P
Sbjct: 3578 LTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPL 3637
Query: 587 TICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNP-NPHLTEVKEWLCLNCQMKRA 645
TI P+ T+ + + T + +P P T + W
Sbjct: 3638 TIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIW---------- 3687
Query: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705
PS L T PV+TT S S ++ P
Sbjct: 3688 -------TPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSV---------VTSTPVTTSTEA 3731
Query: 706 LVKQPTLHGSPSAKAKQPPEADSL-----------SKPAPPKEPSVPSEQDKAPV--ADD 752
+ TL S + P E +L ++ PS+PS + A +
Sbjct: 3732 ISSSATLD-STTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASE 3790
Query: 753 KPKQPKMVKPTTDLVSSSSA------TTKPDIPSSKVQ-SQAEEKTTPP------LKTDS 799
P ++ TT + S+++ TT P S + S+A +TPP L T +
Sbjct: 3791 GSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTST 3850
Query: 800 AKPSQSFPP---------TGEKVSPFD----SKAIPRPASDSKIISHPGPSSESKGQKQV 846
S S P T E+ +P S +P + I S P + +
Sbjct: 3851 KAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPST 3910
Query: 847 DPVQKKEEPKKAQTKMS---------------------PKPDAKPMPKGSPTPPGPRPTA 885
D P +S D P G+ + P T
Sbjct: 3911 DTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTE 3970
Query: 886 GQTVPTPQQSPKPQEQSRRFSLNLGSITDAP------KSQPTTPQETVTG---KLFGFGA 936
T T S + + T AP + P+TP+ T G A
Sbjct: 3971 LNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSA 4030
Query: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQA---------- 986
+ S ++T S P P+ PP P +T +
Sbjct: 4031 TSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVT 4090
Query: 987 -------PPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTET 1023
P S P T P ++ PTV RT T
Sbjct: 4091 TMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTT 4134
Score = 57.4 bits (137), Expect = 4e-07
Identities = 143/692 (20%), Positives = 235/692 (33%), Gaps = 106/692 (15%)
Query: 2547 VTSADYKLPSPTSPLSPHSNKSSPRFSKSLTE-TYVVITLPSEPGTPTDSSASQAITSWP 2605
+TS + + S T +S S + +P S++ +E T TL T S + T P
Sbjct: 91 MTSIESSVTSDTPGVS--STRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVP 148
Query: 2606 LGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTS 2665
+ +PS++ +S F P+ + E Y S + +TP+T + ++PT+
Sbjct: 149 MSTPSEESISSTMAFVSTAPLPSFEA--------YTSLTYKVDMSTPLTTSTQASSSPTT 200
Query: 2666 VTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKPQYKEDGKLQLVG 2725
+ + +E S ++ P+ + S
Sbjct: 201 PESTTIPKSTNSEGSTPLTSMPASTMKVAS-----------------------------S 231
Query: 2726 DVIDLRTVPKVEVKTTDKCIDLSASTMDVKRQITANEVYGKQISAVQPSIINLSVTS--- 2782
+ I L T P VE+ T T+ + + G +S PS + +T
Sbjct: 232 EAITLLTTP-VEISTP--------VTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPL 282
Query: 2783 SIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAMTTPLQLTTSKHAEPPYRIPSDQ 2842
S++ VS T++ + T TE+ A T + +T P
Sbjct: 283 SVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPAS 342
Query: 2843 VFPIAREEAPINLSLGTPAHAVTLAIT--KPVTVPPVGVTNGWTDSTVSQGITDGEVVDL 2900
P+A E LS+ TP TL T +P ++P ST+S+G T + +
Sbjct: 343 TMPVATSEMS-TLSI-TPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPV 400
Query: 2901 ST---------------TKSHRTVVTMDESTSSVMTKIIEDEKPVDLTAGRRAVCCDVVY 2945
ST S V T E++SS T ED T + +
Sbjct: 401 STILVASSEASTTSTIPVDSKTFVTTASEASSSPTTA--EDTSIATSTPSEGST---PLT 455
Query: 2946 KLPFGRSCTAQQPATTL---PEDRFGYRDDHYQYDRSGPYG-YRGIGGMKPSMSDTNLAE 3001
+P + A A+ L P D + S P + PS T L
Sbjct: 456 SMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTS 515
Query: 3002 ---------AGHFFYKSKNAFDYSEGTDTAVDLTSGRVTT-GEVMDYSSKTTGPYPETRQ 3051
+ S D S T+ + +S T G + S+ + G P T
Sbjct: 516 MSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNM 575
Query: 3052 VISGAGISTPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTP------------- 3098
+S + + + ST TP + S SS+ + PT
Sbjct: 576 PVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMS 635
Query: 3099 -STFAITTQPGSIFSTT-VRDLSGIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAV 3156
ST + + S STT V + + T+ TS MP S + T G++
Sbjct: 636 VSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTY-TEGSTPLTSMP 694
Query: 3157 TGIDISASLQTITMESLTAETIDSVPTLTTAS 3188
+ AS + T+ + +T V T T AS
Sbjct: 695 VNTTLVASSEASTLSTTPVDTSTPVTTSTEAS 726
Score = 55.1 bits (131), Expect = 2e-06
Identities = 131/560 (23%), Positives = 191/560 (34%), Gaps = 110/560 (19%)
Query: 2077 TPGSSPTQAPIGEDMTESTMDFDRMP---DASLTSSVLSGASLTDSTSSATLSIPDVKIT 2133
TP ++ T+A +ST MP T+ ++S +T S+T SIP V +
Sbjct: 3723 TPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTS 3782
Query: 2134 QHFSTEEIEDEYVTDY---TREIQEIIAHESLILT--------YSEPSESAT-SVPPSDT 2181
+T T T + S +LT PSE++T S PP DT
Sbjct: 3783 MSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDT 3842
Query: 2182 --PSLTSS-------------VSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEI 2226
P LTS+ + T++ S+P+TTL TT+ T
Sbjct: 3843 STPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTS-------------- 3888
Query: 2227 SSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVA 2286
FPG+ I + S T P AS I ++ + S I E P G
Sbjct: 3889 -----FPGASIASTPPLDTSTTFT-PSTDTASTPTIPVATTISVSVITEGSTP---GTTI 3939
Query: 2287 DTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHP--- 2343
ST + S D +I EL T SS + T F
Sbjct: 3940 FIPSTPVTSSTADVFPATTGAVSTPVITST--------ELNTPSTSSSSTTTSFSTTKEF 3991
Query: 2344 --PSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDI 2401
P+ A P+ TY T + S+ + S S S + P +S +
Sbjct: 3992 TTPAMTTAAPL------TYVTMSTAPSTPRTTSRGCTTSASTLSATSTPH-----TSTSV 4040
Query: 2402 SAQPPPPPPPPPPPP-------PPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVT---T 2451
+ +P P P PP PP PP TS T + + +T + T T
Sbjct: 4041 TTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPST 4100
Query: 2452 ATPLFDAVTT--LETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHR------P 2503
T F VTT + T ++SN T+ P VP + G T
Sbjct: 4101 RTTSFPTVTTTAVPTNTTIKSN--------PTSTPTVPRTTTCFGDGCQNTASRCKNGGT 4152
Query: 2504 EPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSP 2563
P +L DI P P +S +T+ VTS + T L
Sbjct: 4153 WDGLKCQCPNLYYGELCEEVVSSIDIGP-PETISAQMELTVT-VTSVKF-----TEELKN 4205
Query: 2564 HSNKSSPRFSKSLTETYVVI 2583
HS++ F ++ TE ++
Sbjct: 4206 HSSQEFQEFKQTFTEQMNIV 4225
Score = 43.9 bits (102), Expect = 0.004
Identities = 132/626 (21%), Positives = 202/626 (32%), Gaps = 98/626 (15%)
Query: 883 PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQA 942
P T TP +S E + + S T+ S PTTP+ T SI S
Sbjct: 103 PGVSSTRMTPTESRTTSESTSDSTTLFPSSTE-DTSSPTTPEGTDVPMSTPSEESISSTM 161
Query: 943 SNLISTAGQPGPHS---------QSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKS 993
+ +STA P + S P QA + P S PKST P S
Sbjct: 162 A-FVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTS 220
Query: 994 IPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053
+P A ++ + +A T+ T E P+ S ++ P A P+ +P
Sbjct: 221 MP---------ASTMKVASSEAITLLTTPVEIS-TPVTISAQASSSPTTAEGPSLSNSAP 270
Query: 1054 KPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQR 1113
ST PL + L++ +T + TP T I + T+
Sbjct: 271 SGGST-PLTRMPLSVMLVVSSEAST-------------LSTTPAATNIP----VITSTEA 312
Query: 1114 AISGQLGDIRKMP---------PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
+ S + +P P S P AS MPV T S + P + V
Sbjct: 313 SSSPTTAEGTSIPTSTYTEGSTPLTSTP-ASTMPVATSEMSTLSITPVDTSTL------V 365
Query: 1165 KTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEE 1224
T E L E S M+T+ + + L S + IP +
Sbjct: 366 TTSTEPSSLPTTAEATS------MLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVD 419
Query: 1225 EKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLK---SQVQIAEEKLEG--- 1278
K T ED + TS P E L S +A +
Sbjct: 420 SKTFVTTASE-ASSSPTTAEDTSI----ATSTPSEGSTPLTSMPVSTTPVASSEASNLST 474
Query: 1279 -------RVAPKTVQEGKQPQTKMEGLPSGTP------------QSLPKEDDKTTKTIKE 1319
+V T P ++ +P+ TP ++P + + T+
Sbjct: 475 TPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAS-TLST 533
Query: 1320 QPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPS 1379
P T E T E TS+ + +P L++ S+ + SS S
Sbjct: 534 TPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTP--LTNMPVSTRLVVSSEASTTS 591
Query: 1380 LIPTDEKDILKGLKKDSFSQ---ESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKT 1436
P D + + S S E + S ++ +T+ S+ + + E S T
Sbjct: 592 TTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLST 651
Query: 1437 QPHEVSPEQPKDQEKTQSLSETLEIT 1462
P + + E T S S T E T
Sbjct: 652 TPVDSNTPVTTSTEATSS-STTAEGT 676
Score = 40.8 bits (94), Expect = 0.035
Identities = 126/648 (19%), Positives = 211/648 (32%), Gaps = 93/648 (14%)
Query: 3498 GDSMTEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPE 3557
G SM + T+ + ++S+ V T S + + T TP VD + A
Sbjct: 675 GTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLST--TP-----VDTSTPVTTSTEASS 727
Query: 3558 KTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSP- 3616
T S+ +P TS P K T E S D++ + S
Sbjct: 728 SPTTADGASMPTSTPSEGSTP----LTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTE 783
Query: 3617 ----PKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTA 3672
P + + PIS S G L ++ +P I+P P +
Sbjct: 784 ASCSPTTTEGTSMPISTPSEGSPLLTS-------IPVSITPVTSPEASTLSTTPVDSNSP 836
Query: 3673 KMMQRSMSDPKPLSPTADESSRAPFQ-YTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEE 3731
+S SPT E + P Y+EG T S ++++ TL P +
Sbjct: 837 VTTSTEVSS----SPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDT 892
Query: 3732 ISTGTQSTFSTMG-TVSRRRICRTNTMARAK--ILQDIDRELDLVERESAKLRKKQAELD 3788
+ T ST + T S T+T + D +V E+ L A
Sbjct: 893 STPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTL---SATPV 949
Query: 3789 EEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIE 3848
+ + ++ L +++SE S+ T ++
Sbjct: 950 DTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVD 1009
Query: 3849 SQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALP----TQAPTSYT 3904
S P T TE+ PPT+ T S+P+ T+ P S T
Sbjct: 1010 SN-----------------TPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTT 1052
Query: 3905 QQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTP--------TPQPSYQLPSQM 3956
+ E TL T+ ++ S T P TP S + +++
Sbjct: 1053 MVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRL 1112
Query: 3957 MVIQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLE 4016
+V + +TL P TS PV+T + S ++ S+ E
Sbjct: 1113 VVSSE---ASTLSTTPVDTS------------IPVTTSTEASSSPTTAEGTSIPTSPPSE 1157
Query: 4017 ERSSMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALSTAFSLH------- 4069
+ +AS P+S+ S A+ TP +D ++ T A S +
Sbjct: 1158 GTTPLASMPVSTTLVVSSEANTLSTTP-----VDSKTQVATSTEASSPPPTAEVTSMPTS 1212
Query: 4070 ---EKDLSKTDRLLRTTETRRSQEVTDFLAPLQSSSRLHSYVKAEEDP 4114
E+ T +R T S+ T +P+ +S+ + + + P
Sbjct: 1213 TPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSP 1260
Score = 40.0 bits (92), Expect = 0.060
Identities = 48/172 (27%), Positives = 67/172 (38%), Gaps = 18/172 (10%)
Query: 3039 SSKTTGPYPETRQVISGAGISTPQYSTARMTPPPGPQYCVGSVLRSSNGVVYSSVATPTP 3098
S+ +T P VI+ S+ +TA T P Y GS +S VAT
Sbjct: 293 STLSTTPAATNIPVITSTEASSSP-TTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEM 351
Query: 3099 STFAITTQPGSIFSTTVRDLSGIHTADAVTSLPAMHHSQPMPRSYFITTGASETDIAVTG 3158
ST +IT S TT + S + T TS+ +T+ SE +T
Sbjct: 352 STLSITPVDTSTLVTTSTEPSSLPTTAEATSM--------------LTSTLSEGSTPLTN 397
Query: 3159 IDISASLQTITMESLTAE-TIDSVPTLTTASEV--FPEVVGDESALLIVPEE 3207
+ +S L + S T+ +DS +TTASE P D S P E
Sbjct: 398 MPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSE 449
Score = 36.2 bits (82), Expect = 0.86
Identities = 136/670 (20%), Positives = 220/670 (32%), Gaps = 90/670 (13%)
Query: 3502 TEADKTKPLSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTYK 3561
T +D + PL+ SI V T+ S + V T VD + + A
Sbjct: 2745 TPSDGSTPLT---SILVSTLPVASSEASTVST-------TAVDTSIPVTTSTEASSSPTT 2794
Query: 3562 GGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQL-----APSP 3616
T S+T +P TS P + E G S D++ + A S
Sbjct: 2795 AEVTSMPTSTPSETSTP----LTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSS 2850
Query: 3617 PKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVP-------PASP 3669
P + + + PIS S G L ++ P+ + P +P +SP
Sbjct: 2851 PTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSP 2910
Query: 3670 KTAKMMQRSMSDPKPLSP--TADESSRAPFQYTEGYTTK----GSQTMTSSGAQKKVKRT 3723
TA+ +S P +S T+ S P +E T ++T ++ A+ T
Sbjct: 2911 TTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPT 2970
Query: 3724 LPNPPPEEIST-GTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRK 3782
IST G + T T +VS + + ++ D + S+
Sbjct: 2971 TAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTT 3030
Query: 3783 KQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSST 3842
+ + + ++ A+ + V + ++ +EVSS+
Sbjct: 3031 AEGTGIPISTPSEGSTPLTSIPVSTTPVAI----PEASTLSTTPVDSNSPVVTSTEVSSS 3086
Query: 3843 RPTRIESQHGIERP--------------------------RTAPQTEFSQFIPPQTQTES 3876
PT E G P T T P T TE+
Sbjct: 3087 -PTPAE---GTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEA 3142
Query: 3877 QLVPPTSPYTQYQYSSPALP----TQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVA 3932
P TS T S+P+ T P S E TL V T T A
Sbjct: 3143 HSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDT-STPVTTSTEA 3201
Query: 3933 TMSFTPQVQPTPTPQPSYQL-PSQMMVIQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPV 3991
T S T + PT PS + P + + P ++ E I S V N PL
Sbjct: 3202 TSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASS---EASILSTTPVDSNTPL----- 3253
Query: 3992 STDNTFAVSHLGSKYNSLDLRIGLEERSSMASSPISSISADSFYADIDHHTPRN------ 4045
+T + S ++ S+ E + + S P+S+ + S TP +
Sbjct: 3254 TTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVT 3313
Query: 4046 -YVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLLRTTETRRSQEVTDFLAPLQSSSRL 4104
Y I GT+ ++ +S E T+ TT S+ T P+ +S+ +
Sbjct: 3314 TYSQASSSPPIADGTSMPTSTYS--EGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPV 3371
Query: 4105 HSYVKAEEDP 4114
+ +A P
Sbjct: 3372 TTSTEASLSP 3381
Score = 36.2 bits (82), Expect = 0.86
Identities = 140/730 (19%), Positives = 238/730 (32%), Gaps = 70/730 (9%)
Query: 3351 ATEDATTTASAVVAIEIPQSQGWYTVQSDGVTQYIAPPGILSTVSEIPLTDVVVKEEKQP 3410
A+ +A+T ++ V IP + S + + P + + PLT + V
Sbjct: 2764 ASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVA 2823
Query: 3411 KKRSSGAKVRGQYDDMGENMTDDPRSFKKIVDSGVQTDDEDATDRSYVSRRRRTKKSVDT 3470
+ G D T S G+ A++ S + T V T
Sbjct: 2824 SSEA-GTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLL----TSIPVST 2878
Query: 3471 SVQTDDEDQDEWDMPTRSRRKARVGKYGDSM-TEADKTK-PLSKVSSIAVQTVAEISVQT 3528
+ E P + G S T A+ T P+S S ++ + I V T
Sbjct: 2879 TPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTP-LTSILVST 2937
Query: 3529 EPVG-----TIRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSA 3583
PV T+ T + R V S+ T +G S+ T + T +
Sbjct: 2938 VPVAGSEASTLSTTPVDTRTP--VTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVS 2995
Query: 3584 TSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPY 3643
T P + T + ++ + A S P + + PIS S G ++
Sbjct: 2996 TMPVASSEASTLSRTPADTSTPVTTSTE-ASSSPTTAEGTGIPISTPSEGSTPLTS---- 3050
Query: 3644 EKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQ-YTEG 3702
+P +P + P + + +S SPT E + P Y+EG
Sbjct: 3051 ---IPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSS----SPTPAEGTSMPISTYSEG 3103
Query: 3703 YTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFS-TMGTVSRRRICRTNTMARAK 3761
T ++++ TL P + + T ST + + T S T+T +
Sbjct: 3104 STPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGS 3163
Query: 3762 I-LQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRE 3820
L + LV + E+ + A + EA +
Sbjct: 3164 TPLTYMPVSTMLV-------------VSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGT 3210
Query: 3821 RAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVP 3880
+E ++ VS+T E+ T P T TE+ P
Sbjct: 3211 SIPTSTPSEGMTPLTSVPVSNTPVASSEAS-------ILSTTPVDSNTPLTTSTEASSSP 3263
Query: 3881 PTSPYTQYQYSSPALP----TQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSF 3936
PT+ T S+P+ T P S T + E TL +P T + S
Sbjct: 3264 PTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTL---STTPADTSTPVTTYSQASS 3320
Query: 3937 TPQV-QPTPTPQPSYQLPSQMMVIQQKPRQTTLYLEPKITSNYEVIRNQPL-MIAPVSTD 3994
+P + T P +Y S + + P ++S + P+ PV+T
Sbjct: 3321 SPPIADGTSMPTSTYSEGSTPLT------NMSFSTTPVVSSEASTLSTTPVDTSTPVTTS 3374
Query: 3995 NTFAVSHLGSKYNSLDLRIGLEERSSMASSPISSISADSFYADIDHHTPRNYVLIDDIGE 4054
++S ++ S+ E + +AS P+S+ S + TP +D
Sbjct: 3375 TEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTP-----VDSNTL 3429
Query: 4055 ITKGTAALST 4064
+T T A S+
Sbjct: 3430 VTTSTEASSS 3439
Score = 35.0 bits (79), Expect = 1.9
Identities = 109/588 (18%), Positives = 198/588 (33%), Gaps = 76/588 (12%)
Query: 3502 TEADKTKPLSKVSSIAVQTVAEIS-------VQTEPVGTIRTPSIRAR-VDAKVEIIKHI 3553
+EA + ++ +SIA T +E S V T PV + ++ VD+K ++
Sbjct: 428 SEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTST 487
Query: 3554 SAPEK--TYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPT--PLEIGYSSHLRADST 3609
A T + S+ T ++ T +T P + T + S+ + S
Sbjct: 488 EASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSE 547
Query: 3610 VQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASP 3669
+ + P+ + P S S G PL + +++ A +P
Sbjct: 548 ASSSSTTPEGTSI---PTSTPSEGST----------PLTNMPVSTRLVVSSEASTTSTTP 594
Query: 3670 KTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPP 3729
+ + S+ S TA+ +S Y+E TT S +++++ TL P
Sbjct: 595 ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPV 654
Query: 3730 EE---ISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRKKQAE 3786
+ ++T T++T S+ T T + + E++ L
Sbjct: 655 DSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPV- 713
Query: 3787 LDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTR 3846
+ + ++ L + + ++ SE S+ T
Sbjct: 714 --DTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTP 771
Query: 3847 IESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPA----LPTQAPTS 3902
+++ I T TE+ P T+ T S+P+ L T P S
Sbjct: 772 LDTSTHI-----------------TTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVS 814
Query: 3903 YTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQ-----MM 3957
T + E TL T P + + ++ + +V +PTP +P+
Sbjct: 815 ITPVTSPEASTL--------STTPV-DSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRT 865
Query: 3958 VIQQKPRQTTLYLEPKITSNYEVIRNQPL-MIAPVSTDNTFAVSHLGSKYNSLDLRIGLE 4016
+ P TTL TS + P+ PV+ S S+ S+ E
Sbjct: 866 PLTSMPVSTTLV----ATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGE 921
Query: 4017 ERSSMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKGTAALST 4064
+ + S P S+ S A TP +D +T T A S+
Sbjct: 922 GSTPLTSMPDSTTPVVSSEARTLSATP-----VDTSTPVTTSTEATSS 964
Score = 34.7 bits (78), Expect = 2.5
Identities = 53/216 (24%), Positives = 76/216 (35%), Gaps = 27/216 (12%)
Query: 3858 TAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQ----APTSYTQQSHFEQQT 3913
T T P T TE P T+ T Q S+P+ T P S T E T
Sbjct: 2004 TLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNT 2063
Query: 3914 LYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQQ-----KPRQTTL 3968
L V +TQ T A+ S T + PS P + P +TL
Sbjct: 2064 LSTTPVDS-KTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTL 2122
Query: 3969 YLEPKITSNYEVIRNQPLMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERSSMASSPISS 4028
P + SN VI + + +P+ T+ T S+ + R+ + S P+S+
Sbjct: 2123 STTP-VDSNSPVITSTEVSSSPIPTEGT-----------SMQTSTYSDRRTPLTSMPVST 2170
Query: 4029 ISADSFYADIDHHTPRNYVLIDDIGEITKGTAALST 4064
S TP +D +T T A S+
Sbjct: 2171 TVVASSAISTLSTTP-----VDTSTPVTNSTEARSS 2201
Score = 34.3 bits (77), Expect = 3.3
Identities = 53/255 (20%), Positives = 93/255 (36%), Gaps = 33/255 (12%)
Query: 3498 GDSMTEADKTKPLSKVSSIAVQTVAEISVQTE-----PVGTIRTPSIRARVDAKVEIIKH 3552
G SM ++ ++ + ++SI V T +S + PV T + A + +
Sbjct: 1383 GTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEG 1442
Query: 3553 ISAPEKTYKGGSLGCQTEADSDTQSPQYLSAT--SPPKDKKRPTPLEIGYSSHLRADSTV 3610
IS P T G ++ S+T ++T + P D P SS
Sbjct: 1443 ISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSS-------- 1494
Query: 3611 QLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPK 3670
+P+P + + S +P AL S V +I+ ++ P +
Sbjct: 1495 --SPTPAEGTSIAIS--TPSEGSTALTSIPVSTTTVASSEIN-------SLSTTPAVTST 1543
Query: 3671 TAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGS---QTMTSSGAQKKVKRTLPNP 3727
++ S P TAD +S Y+EG T S TM ++ T P
Sbjct: 1544 PVTTYSQASSSPT----TADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPID 1599
Query: 3728 PPEEISTGTQSTFST 3742
+++ T+++ ST
Sbjct: 1600 SKTQVTASTEASSST 1614
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 117 bits (293), Expect = 3e-25
Identities = 100/321 (31%), Positives = 121/321 (37%), Gaps = 32/321 (9%)
Query: 274 LQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA 333
L D S Q + ++ G PS +KP P PGKP P GP PP
Sbjct: 19 LNEDVS--QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP-PPG 75
Query: 334 QPSGLTKPLAQQPGTVKPPVQPPGTTKPPA---QPLGPAKPPAQQTGSEKPSSEQP-GPK 389
+P G + PP +P G PP QP GP PP + G +P GP
Sbjct: 76 KPQGPPPQGDKSRSPRSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP 133
Query: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
PPG + P Q ++ P G P+ Q G Q P P K P GK
Sbjct: 134 ----PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189
Query: 450 PAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP--GPAKPPPQQPGSAKPPSQQPGST 507
P PGK P PP Q G Q P P PPPQ + P PG
Sbjct: 190 PQGPPPPGK-------PQGPPPQ--GDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKP 240
Query: 508 KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
+ PP Q G P PG + P Q GS SA+ P P KP P Q G+
Sbjct: 241 QGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP-PGKPQG-----PPQQEGNNPQG 294
Query: 568 QPPTVSPSAKQP--PSQGLPK 586
PP + +QP P G P+
Sbjct: 295 PPPPAGGNPQQPQAPPAGQPQ 315
Score = 115 bits (289), Expect = 9e-25
Identities = 130/415 (31%), Positives = 156/415 (37%), Gaps = 99/415 (23%)
Query: 162 ALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQG-KPEGIIKPPLQQQPPKPIP 220
AL A+SS N + + SQEE+ + QG P+G KP Q PP P
Sbjct: 9 ALLALSSAQNL--------NEDVSQEESPSL--IAGNPQGPSPQGGNKP---QGPPPPPG 55
Query: 221 KQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR 280
K QGP P Q P+ PP GKP QGP PQ D ++ P
Sbjct: 56 KPQGP---PPQGGNKPQG------------PPPPGKP-QGPP--PQGDKSRSP------- 90
Query: 281 PQTKQADIVRGESVKPSLPSP---SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG 337
R KP P P ++P P PGKP P GP PP +P G
Sbjct: 91 ---------RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP-PPGKPQG 140
Query: 338 LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP-KALAQPPG 396
PP Q + P + P P PP Q G +P P P K PP
Sbjct: 141 -------------PPPQGDKSRSPRSPPGKPQGPPPQ--GGNQPQGPPPPPGKPQGPPPQ 185
Query: 397 VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGP 456
GK P P P KP G P + QSP PG + P Q G Q GP
Sbjct: 186 GGKKPQGPPPPGKPQ----GPPPQGDKSRSSQSP---PGKPQGPPPQGG-----NQPQGP 233
Query: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ-PGSTKPPPQQPG 515
+ GP PP P PPP PG + PP Q GS ++ PG + PPQQ G
Sbjct: 234 PPPPGKPQGP--PPQGGNKPQGPPP--PGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG 289
Query: 516 PAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
P P P QQP A P+ Q P +P G+P +PP
Sbjct: 290 NNPQGPPPPAGGNP--QQP-QAPPAGQPQGPPRPPQ-----------GGRPSRPP 330
Score = 70.1 bits (170), Expect = 5e-11
Identities = 89/345 (25%), Positives = 113/345 (32%), Gaps = 60/345 (17%)
Query: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709
+A P P P+ P K P Q K P +P+ PPP +
Sbjct: 32 IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPG-----KPQGPPPQGDK 86
Query: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769
SP K + PP PP P P Q P ++P+ P
Sbjct: 87 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP--QGPPPQGGNRPQGPP----------- 133
Query: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSK 829
KP P + ++ +PP K P P G P + P P K
Sbjct: 134 --PPGKPQGPPPQ-GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG-PPPQGGKK 189
Query: 830 IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMPKGSPTPPGPRPTAGQ 887
P P G+ Q P Q K+++ SP KP P P+G P GP P G+
Sbjct: 190 PQGPPPP-----GKPQGPPPQGD----KSRSSQSPPGKPQGPP-PQGGNQPQGPPPPPGK 239
Query: 888 TV-PTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLI 946
P PQ KPQ P P GK G A S++ +
Sbjct: 240 PQGPPPQGGNKPQG-------------------PPPP-----GKPQGPPAQGGSKSQSAR 275
Query: 947 STAGQP-GPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990
S G+P GP Q G PA P Q PP Q PP P
Sbjct: 276 SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 320
Score = 64.7 bits (156), Expect = 2e-09
Identities = 97/384 (25%), Positives = 126/384 (32%), Gaps = 106/384 (27%)
Query: 661 LKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSK--APEPKKPPPLVKQPTLHGSPSA 718
L A + +SA + + Q+ SP A Q S +P+ PPP +P G P
Sbjct: 6 LSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKP--QGPPPQ 63
Query: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
+P P PP +P P P DK + P+ S KP
Sbjct: 64 GGNKP------QGPPPPGKPQGP------PPQGDKSRSPR------------SPPGKPQG 99
Query: 779 PSSKVQSQAEEKTTPPLKTDSAKPS-----QSFPPTGEKVSPFDSKAIPRPASDSKIISH 833
P + +Q + PP K P Q PP G+ P P K S
Sbjct: 100 PPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP--------PPQGDKSRSP 151
Query: 834 PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPM---PKGSPTPPGPRPTAGQTVP 890
P G+ Q P Q +P+ P P KP P+G P GP P P
Sbjct: 152 RSPP----GKPQGPPPQGGNQPQGP-----PPPPGKPQGPPPQGGKKPQGPPP------P 196
Query: 891 TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAG 950
Q P PQ R S +S P PQ
Sbjct: 197 GKPQGPPPQGDKSRSS----------QSPPGKPQ-------------------------- 220
Query: 951 QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTG---QAPPAPAK--SIPVKKETKAPAA 1005
GP Q G P P P +P QGPP G Q PP P K P + +K+ +A
Sbjct: 221 --GPPPQGG-NQPQGPPPPPGKP---QGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSA 274
Query: 1006 EKLEPKAEQAPTVKRTETEKKPPP 1029
K + P + + PPP
Sbjct: 275 RSPPGKPQGPPQQEGNNPQGPPPP 298
Score = 57.8 bits (138), Expect = 3e-07
Identities = 66/262 (25%), Positives = 88/262 (33%), Gaps = 30/262 (11%)
Query: 648 GDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP--QQTSPKKDAAPKQDLSKAPEPKKPPP 705
GD + P SP K + P + P P Q P + Q +P+ PPP
Sbjct: 84 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPP 143
Query: 706 LVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPS----EQDKAPVADDKPKQPKMVK 761
+ SP K + PP PP P P + K P P +P+
Sbjct: 144 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP 203
Query: 762 PTTDLV-SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKA 820
P D SS S KP P + +Q + PP K P P G
Sbjct: 204 PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP--------- 254
Query: 821 IPRPASDSKIISHPGPSSESK----GQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSP 876
P P + G S+S G+ Q P Q+ P+ P P A P+
Sbjct: 255 -PPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ------GPPPPAGGNPQQPQ 307
Query: 877 TPPGPRPTAGQTVPTPQQSPKP 898
PP +P Q P P Q +P
Sbjct: 308 APPAGQP---QGPPRPPQGGRP 326
Score = 56.6 bits (135), Expect = 6e-07
Identities = 67/262 (25%), Positives = 88/262 (33%), Gaps = 17/262 (6%)
Query: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSP-QPQQTSPKKDAAPKQDLSKAPEPKKPPP 705
GG+ P P P S +S P +PQ P+ P+ +P+ PPP
Sbjct: 64 GGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 123
Query: 706 L-VKQPTLHGSPSAKAKQPPEADSLSKP-APPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763
+P P PP+ D P +PP +P P Q P K P
Sbjct: 124 QGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 183
Query: 764 TDLVSSSSATTKPDIPSSKVQ--SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI 821
P P ++ +PP K P P G P +
Sbjct: 184 PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQG- 242
Query: 822 PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMPKGSPTPP 879
P P +K P P G+ Q P Q K+Q+ SP KP P +G+ P
Sbjct: 243 PPPQGGNKPQGPPPP-----GKPQGPPAQ---GGSKSQSARSPPGKPQGPPQQEGN-NPQ 293
Query: 880 GPRPTAGQTVPTPQQSPKPQEQ 901
GP P AG PQ P Q Q
Sbjct: 294 GPPPPAGGNPQQPQAPPAGQPQ 315
Score = 45.4 bits (106), Expect = 0.001
Identities = 46/173 (26%), Positives = 56/173 (32%), Gaps = 14/173 (8%)
Query: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP--------PPPPP 2422
KP P G P +P D S P PP P PPP PPPPP
Sbjct: 117 KPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 176
Query: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482
P PPP K P P P D + ++ P
Sbjct: 177 GKPQGPPPQGGKKPQGPPPPGKPQGP----PPQGDKSRSSQSPPGKPQGPPPQGGNQPQG 232
Query: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTG 2535
PPP P KP P ++P+ PP P+ Q + +Q KP G
Sbjct: 233 PPPPPGKPQGPPP--QGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQG 283
Score = 43.1 bits (100), Expect = 0.007
Identities = 54/218 (24%), Positives = 69/218 (31%), Gaps = 39/218 (17%)
Query: 840 SKGQKQVDPVQKKEEPKK-AQTKMSPKPDAKPMPKGSPTPPG----PRPTAGQTVPTPQQ 894
S Q + V ++E P A P P P+G P PPG P P G P
Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP 73
Query: 895 SPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP-G 953
KPQ + G + +P+S P PQ G +Q G+P G
Sbjct: 74 PGKPQGPPPQ-----GDKSRSPRSPPGKPQ--------GPPPQGGNQPQGPPPPPGKPQG 120
Query: 954 PHSQSG--------PGAPM------------KQAPAPSQPPTSQGPPKSTGQAPPAPAKS 993
P Q G PG P + P Q P QG + G PP
Sbjct: 121 PPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 180
Query: 994 IPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIK 1031
P + K P K + P + PP K
Sbjct: 181 GPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGK 218
Score = 42.4 bits (98), Expect = 0.012
Identities = 41/152 (26%), Positives = 45/152 (29%), Gaps = 20/152 (13%)
Query: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP--------PPPPP 2422
KP P G P +P D S P PP P PPP PPPPP
Sbjct: 56 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 115
Query: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482
P PPP P P P D + + P
Sbjct: 116 GKPQGPPPQGGNRPQGPPPPGKPQGP----PPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 171
Query: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
PPP P KP P P+ K P P P
Sbjct: 172 PPPPPGKPQGPP--------PQGGKKPQGPPP 195
Score = 40.8 bits (94), Expect = 0.035
Identities = 41/142 (28%), Positives = 46/142 (32%), Gaps = 39/142 (27%)
Query: 2404 QPPPPPPPPPPPPPP--------PPPPPPPPLPPPTSPKPTI--LPKKKLTVASPVTTAT 2453
Q PPPPP P PPP PPPP P PPP K P K P
Sbjct: 48 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 107
Query: 2454 PLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPK 2513
P PPP P KP P +RP+ PP P+
Sbjct: 108 P--------------------------QGPPPPPGKPQGPPP--QGGNRPQGPPPPGKPQ 139
Query: 2514 PVIPQLPTTTQKPTDIHPKPTG 2535
PQ ++ P KP G
Sbjct: 140 GPPPQ-GDKSRSPRSPPGKPQG 160
Score = 38.5 bits (88), Expect = 0.17
Identities = 26/73 (35%), Positives = 30/73 (41%), Gaps = 10/73 (13%)
Query: 2364 GETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPP----PPP 2419
G+ G + P G P P KP+ S+Q PP P PPP P
Sbjct: 177 GKPQGPPPQGGKKPQGPPP----PGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQG 232
Query: 2420 PPPPP--PPLPPP 2430
PPPPP P PPP
Sbjct: 233 PPPPPGKPQGPPP 245
Score = 37.7 bits (86), Expect = 0.30
Identities = 34/124 (27%), Positives = 42/124 (33%), Gaps = 7/124 (5%)
Query: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTG---QAPPAPAKSIPV 996
SQ + AG P S G P P P +P QGPP G Q PP P K
Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKP---QGPPPQGGNKPQGPPPPGKPQGP 80
Query: 997 KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056
+ + + P Q P + + PPP K PQ P KP+
Sbjct: 81 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP-PPGKPQGPPPQGGNRPQGPPPPGKPQ 139
Query: 1057 STCP 1060
P
Sbjct: 140 GPPP 143
Score = 36.6 bits (83), Expect = 0.66
Identities = 22/69 (31%), Positives = 29/69 (42%)
Query: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431
P +Q S S S S P KP+ + + PPP P P PP P P PP
Sbjct: 263 PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 322
Query: 2432 SPKPTILPK 2440
+P+ P+
Sbjct: 323 GGRPSRPPQ 331
Score = 32.7 bits (73), Expect = 9.6
Identities = 26/77 (33%), Positives = 30/77 (38%), Gaps = 13/77 (16%)
Query: 2371 KPASQLPSGS--PSVSSLPAKPR-PFFRSSSLDISAQPPPPPPPPPPPPP---PPPPPPP 2424
KP P G P P KP+ P + S SA+ PP P PP P PPPP
Sbjct: 239 KPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPP 298
Query: 2425 -------PPLPPPTSPK 2434
P PP P+
Sbjct: 299 AGGNPQQPQAPPAGQPQ 315
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 116 bits (291), Expect = 5e-25
Identities = 192/923 (20%), Positives = 322/923 (34%), Gaps = 137/923 (14%)
Query: 13 PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERR------QIAAVMSRAQGL 66
P + A ++ +S + S S ++ E +L+E + + Q+AA+ Q
Sbjct: 476 PTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNK 535
Query: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP 126
PK + H+++E + K + P P + + S S + + +
Sbjct: 536 PKKKEKDKKEKKKEKHKRKE-EVEENKKSKAKEPPPKKTKKNNSSNSNVSK--KEPAPMK 592
Query: 127 GRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSA--VSSVVNKFNPFDLISDSEA 184
+ P T +E + E K + ++N L + VV+ +I E
Sbjct: 593 SKPPPTYESEEEDKCKPMSYEEKRQLS----LDINKLPGEKLGRVVH------IIQSREP 642
Query: 185 SQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGR---DPLQQDGTPKSISS 241
S + + + + E KP + + L++ + K++ P D + K SS
Sbjct: 643 SLKNSNPDEIEIDFETLKPSTLRE--LERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSS 700
Query: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHA-KLPLQRDASRPQTKQADIVRGESVKPSLPS 300
+ E + + ++ +T+ A K + R Q K + + P
Sbjct: 701 SESES-------SSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPV 753
Query: 301 PSKPPI--QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQ 354
P +PP QQP P PP QQ + P P PP+ P + P T P ++
Sbjct: 754 PQQPPPPPQQPPPPPPPQQQ----QQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLE 809
Query: 355 P--PGTTKPP----AQPL----GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQ 404
P PG+ P QP+ P PP E + A+ PP + QQ
Sbjct: 810 PQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQ 869
Query: 405 PG------------PAKPPTQQVG-TPKPLAQQPGLQSPAKA-------PGPTKTPVQQP 444
P PA+PP T PL QP + P + P P T +Q
Sbjct: 870 PSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQ 929
Query: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504
+ + P ++PP LP P P QQ +PPP P +PP QQ
Sbjct: 930 LYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQ- 988
Query: 505 GSTKPPPQ----QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
+PPP+ QP QQP PP Q P QQP P +P+ Q
Sbjct: 989 -QHQPPPRPVHLQPMQFSTHIQQP---PPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHH 1044
Query: 561 TGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620
+ P + + P + L++H P+ + F + T
Sbjct: 1045 SPRHHKSDPYSTGHLREAP---------------SPLMIHSPQMSQFQSLTHQSP----- 1084
Query: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ 680
P ++ K+ L A PQP + S + +S P
Sbjct: 1085 ----PQQNVQPKKQEL-------------RAASVVQPQPLVVVKEEKIHSPIIRSEPFSP 1127
Query: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740
P+ P+ + P++P +P G P + PPE ++ AP K+
Sbjct: 1128 SLRPEPPKHPESIKAPVHLPQRPE---MKPVDVGRPVIR---PPEQNAPPPGAPDKDKQ- 1180
Query: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE----KTTPPLK 796
++ K PVA K + K + LV P PSS +S ++ + K
Sbjct: 1181 -KQEPKTPVAPKKDLKIKNMGSWASLVQK-----HPTTPSSTAKSSSDSFEQFRRAAREK 1234
Query: 797 TDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPK 856
+ K ++ EK + R D + + E ++Q Q+++E +
Sbjct: 1235 EEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQ 1294
Query: 857 KAQTKMSPKPDAKPMPKGSPTPP 879
+ Q + + A P+ + P
Sbjct: 1295 QQQQQQAAAVAAAATPQAQSSQP 1317
Score = 95.5 bits (236), Expect = 1e-18
Identities = 249/1201 (20%), Positives = 398/1201 (33%), Gaps = 180/1201 (14%)
Query: 221 KQQGPGRDPLQQDGTPKSISSQQPEKIK-SQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279
K +G GR ++ GT K S P + S PP T P P T H P
Sbjct: 177 KGRGRGR---KETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHP-FPAVTPDL 232
Query: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339
QT +V P P + PP+ P P PPA P +S P QP
Sbjct: 233 IVQTPVMTVV------PPQPLQTPPPVP-PQPQPPPAPAPQPVQSHPPIIAATPQPVKTK 285
Query: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399
K + ++ T P P +PP+ P +P + G + SS P P
Sbjct: 286 KGVKRKADTTTPTTIDP-IHEPPSL---PPEPKTTKLGQRRESSRPVKPPKKDVPDS--- 338
Query: 400 TPAQQPGPAKPP--TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG---------- 447
Q P P K ++Q+ + ++ + A P PV G
Sbjct: 339 --QQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKH 396
Query: 448 -----KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
I ++ AQ+ G PP A Q ++
Sbjct: 397 PMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 456
Query: 503 QPGSTKPPPQQPGPAKPSPQQPGSTK---PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559
P P++P A SP P TK PPS S+ S+ S S ++ + ++
Sbjct: 457 MPDE----PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
Query: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH-----------------VP 602
+ + L+ +A P Q PK + H P
Sbjct: 513 EL--QEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPP 570
Query: 603 EKANFNTCTECQTTVCSLCGF--NPNPHLTEVKEWLC--LNCQMKRALGGDLAPVPSSPQ 658
+K N + + P P +E C ++ + KR L D+ +P
Sbjct: 571 KKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKL 630
Query: 659 PKLKTAPVTTTSAVSKSSPQP-----QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
++ + ++ S+P + P ++ ++ K+ P K +
Sbjct: 631 GRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIA 690
Query: 714 GSPSAKAKQPPEADSLSK--------------PAPPKEPSVPSEQDK------------- 746
GS K E++S S+ P K+ EQ K
Sbjct: 691 GSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAP 750
Query: 747 APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPP--LKT-----DS 799
APV P P+ P P PS Q+ K++PP + T +
Sbjct: 751 APVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEP 810
Query: 800 AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ--VDP-------VQ 850
P F P G P +P+P + P S+ + V P Q
Sbjct: 811 QLPGSVFDPIGHFTQPI--LHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQ 868
Query: 851 KKEEPKKAQTKMSPKPDAKP--MPKGSPTPPGPRPTAG---QTVPTPQQSPKPQEQSRRF 905
+ P + PKP P P + TP P+P Q + ++ P P S +
Sbjct: 869 QPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQM 928
Query: 906 SLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMK 965
L L + K QP TP + SQ + P Q ++
Sbjct: 929 QLYLQQL---QKVQPPTPLLP--------SVKVQSQPPPPLPPPPHPSVQQQ------LQ 971
Query: 966 QAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEK 1025
Q P P PP Q PP+ Q PP P P++ T + P+ +Q P +
Sbjct: 972 QQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTH--IQQPPPPQGQQPPHPPPGQQPP 1029
Query: 1026 KPPPIKDSK------SLTAEPQKAVLPTKLEKSPKPEST-CPLCKTELNIGSKDPPNFNT 1078
P P K + S L ++P P P ++ + PP N
Sbjct: 1030 PPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNV 1089
Query: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPP----------- 1127
+ K ++ P P + +E + S L R PP
Sbjct: 1090 QPK-KQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSL---RPEPPKHPESIKAPVH 1145
Query: 1128 APSGPKASPMPV--PTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS---- 1181
P P+ P+ V P ++ A PP KQ+QE KT K+K S
Sbjct: 1146 LPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASL 1205
Query: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKP 1241
++K P ++ K E+ + +A +++ E +K + + + +EK+ L +E+
Sbjct: 1206 VQKHPTTPSSTAKSSSDSFEQFRRAAREKE----EREKALKAQAEHAEKEKERLRQERMR 1261
Query: 1242 TPEDKKLLPEAKTSAPE-----EQKHDLLKSQVQIAEEKLEGRVAPKTVQ-EGKQPQTKM 1295
+ ED+ L +A+ + E EQ+ + Q Q +++ A T Q + QPQ+ +
Sbjct: 1262 SREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSML 1321
Query: 1296 E 1296
+
Sbjct: 1322 D 1322
Score = 88.2 bits (217), Expect = 2e-16
Identities = 250/1307 (19%), Positives = 451/1307 (34%), Gaps = 226/1307 (17%)
Query: 374 QQTGSEKPS-SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL--QSP 430
++TG+ KP S P + PP Q P P PP Q P P A P L Q+P
Sbjct: 184 KETGTAKPGVSTVPNTTQASTPP-----QTQTPQPNPPPVQATPHPFP-AVTPDLIVQTP 237
Query: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ------QP 484
P + P+Q P P +P Q P PP+ P P + P QP
Sbjct: 238 VMTVVPPQ-PLQTPPP--VPPQ-------------PQPPPAPAPQPVQSHPPIIAATPQP 281
Query: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544
K ++ P+ +PP P P Q + P + P P +QQ
Sbjct: 282 VKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQH 341
Query: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEK 604
+ S++ S + +G K + + A P + + L + +++ H +
Sbjct: 342 PAPEKSSKVSEQLKCCSGILKEMFAKKHAAYA-WPFYKPVDVEALGLHDYCDIIKHPMDM 400
Query: 605 ANFNTCTECQ------------TTVCSLC-GFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651
+ + E + + S C +NP H E + + +++ A
Sbjct: 401 STIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDH-----EVVAMARKLQDVFEMRFA 455
Query: 652 PVPSSPQPKL----KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707
+P P+ + A T V+ S + D+ D S+ ++ L
Sbjct: 456 KMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQ 515
Query: 708 KQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767
+Q A QP + K KE + K V ++K + K P
Sbjct: 516 EQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKK 575
Query: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
++SS S +K P+K +KP PPT E S + K P +
Sbjct: 576 NNSS------------NSNVSKKEPAPMK---SKP----PPTYE--SEEEDKCKPMSYEE 614
Query: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
+ +S + +V + + EP + + PD + + P R
Sbjct: 615 KRQLSLDINKLPGEKLGRVVHIIQSREP----SLKNSNPDEIEIDFETLKPSTLRELERY 670
Query: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
++ KP Q+ + + GS K+ GF +S S++S+ S
Sbjct: 671 VTSCLRKKRKP--QAEKVDVIAGS-----------------SKMKGFSSS-ESESSSESS 710
Query: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
++ ++ P + K P Q + QAP AP ++
Sbjct: 711 SSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAP--------------APVPQQ 756
Query: 1008 LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELN 1067
P +Q P + +++PPP S+ PQ+A K P + P+ + +L
Sbjct: 757 PPPPPQQPPPPPPPQQQQQPPPPPPPPSM---PQQAAPAMKSSPPPFIATQVPVLEPQLP 813
Query: 1068 IGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPP 1127
DP T + +L PHL + E Q A+ +P
Sbjct: 814 GSVFDPIGHFT-----QPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQ 868
Query: 1128 APSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPP 1187
PS P +P + ++ AV P + Q + +V+LE E P
Sbjct: 869 QPSRPSNRAAALPPK-PARPPAVSPALTQTPLLPQPPMAQPPQVLLE------DEEPPAP 921
Query: 1188 MVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPL-----------L 1236
+T+ Q Q LQ+ + + L+P K++S+ PL L
Sbjct: 922 PLTSMQMQ----------LYLQQLQKVQPPTPLLP-SVKVQSQPPPPLPPPPHPSVQQQL 970
Query: 1237 EEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKME 1296
+++ P P P + P +Q+H V + + + +G+QP
Sbjct: 971 QQQPPPP------PPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPP 1024
Query: 1297 GLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS 1356
G +QP PP AKP QV Q S
Sbjct: 1025 G---------------------QQPPPPQPAKPQQV------------------IQHHHS 1045
Query: 1357 PQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTV 1416
P+ YS + L E PS + + + S + +S P K E
Sbjct: 1046 PRHHKSDPYS----TGHLREAPSPLMIHSPQM---SQFQSLTHQSPPQQNVQPKKQELRA 1098
Query: 1417 LSILEAQASTLADEKSEK----KTQPHEVS--PEQPKDQEKTQS------LSETLEITIS 1464
S+++ Q + E+ +++P S PE PK E ++ E + +
Sbjct: 1099 ASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVG 1158
Query: 1465 EEEIKESQEER-------KDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESS 1517
I+ ++ KD K++ + + KD K K+ + + + + + S+
Sbjct: 1159 RPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKN--MGSWASLVQKHPTTPSST 1216
Query: 1518 ESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDA---SGSED 1574
+S ++ RR + ++ + ++ + +E++ +R++ + DEDA +
Sbjct: 1217 AKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAH 1276
Query: 1575 DEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDE 1621
+E R Q ++ E Q++++ + A + + + + +D+
Sbjct: 1277 EEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQ 1323
Score = 67.0 bits (162), Expect = 5e-10
Identities = 59/197 (29%), Positives = 78/197 (39%), Gaps = 37/197 (18%)
Query: 2401 ISAQPPPPPPPPPPPPP------PPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTAT- 2453
+ QPPPPP PPPPPP PPPPPPPP +P +P P + PV
Sbjct: 753 VPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQL 812
Query: 2454 --PLFDAVTTLETTAV-LRSNGLP--------------VTRICTTAPPPVP---PKPSSI 2493
+FD + + L LP + + +PP + P+ S
Sbjct: 813 PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSR 872
Query: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHP-------KPTGLSLTSSMTLNL 2546
PS P+P++PP A P + Q P Q P P +P LT SM + L
Sbjct: 873 PSNRAAALPPKPARPP-AVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLT-SMQMQL 930
Query: 2547 VTSADYKLPSPTSPLSP 2563
K+ PT PL P
Sbjct: 931 YLQQLQKVQPPT-PLLP 946
Score = 60.5 bits (145), Expect = 4e-08
Identities = 60/241 (24%), Positives = 87/241 (36%), Gaps = 46/241 (19%)
Query: 2404 QPPPPPPPPPPPPPPPPPPPPPP---LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460
Q P P P PPPPP PPPPPPP PP P P +P++ A+P ++
Sbjct: 748 QAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQ----AAPAMKSS------- 796
Query: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI--PSG---LVFTHRPEPSKPPIAPKPV 2515
P I T P P P S+ P G H P+P PP P+P
Sbjct: 797 -------------PPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPP 843
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
P P ++ S L+ PS + P P S +
Sbjct: 844 EHSTP----------PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPA 893
Query: 2576 LTETYVV----ITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEI 2631
LT+T ++ + P + + + +TS + + L V+P ++P V
Sbjct: 894 LTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQ 953
Query: 2632 P 2632
P
Sbjct: 954 P 954
Score = 60.1 bits (144), Expect = 6e-08
Identities = 52/174 (29%), Positives = 64/174 (36%), Gaps = 33/174 (18%)
Query: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQP-----PPPPPPPPPPPPPPPPPPPPP 2426
P +Q P +P + A P PF + I P PP P PPP PP P PPP P
Sbjct: 206 PQTQTPQPNPP--PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP 263
Query: 2427 LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV 2486
P P P P+ ATP V T + P T PP +
Sbjct: 264 APQPVQSHP------------PIIAATP--QPVKTKKGVKRKADTTTPTTIDPIHEPPSL 309
Query: 2487 PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540
PP+P + G R E S+P PK +P + HP P S S
Sbjct: 310 PPEPKTTKLG----QRRESSRPVKPPKKDVPD--------SQQHPAPEKSSKVS 351
Score = 59.7 bits (143), Expect = 7e-08
Identities = 58/217 (26%), Positives = 75/217 (34%), Gaps = 58/217 (26%)
Query: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP-----PPP---- 2420
+ P LPS P P P S + QPPPPPPP P PPP PPP
Sbjct: 939 QPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVH 998
Query: 2421 ------------PPPP----PPLPPPTSPKPTILPKKKLTV------------------- 2445
PPPP PP PPP P P K V
Sbjct: 999 LQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGH 1058
Query: 2446 ----ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA-----PPPVPPKPSSIPSG 2496
SP+ +P +L + + N P + A P V K I S
Sbjct: 1059 LREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSP 1118
Query: 2497 LVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKP 2533
++ R EP P + P+P P+ P + + P + +P
Sbjct: 1119 II---RSEPFSPSLRPEP--PKHPESIKAPVHLPQRP 1150
Score = 55.8 bits (133), Expect = 1e-06
Identities = 78/320 (24%), Positives = 109/320 (34%), Gaps = 78/320 (24%)
Query: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP-----------------PP 2413
KPA P+ SP+++ P P+P + PP PP PP
Sbjct: 883 KPARP-PAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941
Query: 2414 PP---------PPPPPPPPP------------PPLPPPTSPKPTILPKKKLTVASPVTTA 2452
P PPPP PPP PP PPP P+P P ++ P
Sbjct: 942 TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQP---PPQQQHQPPPRPVH 998
Query: 2453 TPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPP--- 2509
T ++ + P PPP P KP + + H P K
Sbjct: 999 LQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQV---IQHHHSPRHHKSDPYS 1055
Query: 2510 -----IAPKPVI---PQL----PTTTQKPTDIHPKPTGLSLTSSMTLN---LVTSADYKL 2554
AP P++ PQ+ T Q P + +P L ++ + LV + K+
Sbjct: 1056 TGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKI 1115
Query: 2555 PSP---TSPLSPHSNKSSPRFSKSLTETYVVITLPSEP-------GTPTDSSASQAITSW 2604
SP + P SP P+ +S+ + LP P G P Q +
Sbjct: 1116 HSPIIRSEPFSPSLRPEPPKHPESIK---APVHLPQRPEMKPVDVGRPVIRPPEQ--NAP 1170
Query: 2605 PLGSPSKDLVSVEPVFSVVP 2624
P G+P KD EP V P
Sbjct: 1171 PPGAPDKDKQKQEPKTPVAP 1190
Score = 53.9 bits (128), Expect = 4e-06
Identities = 126/625 (20%), Positives = 224/625 (35%), Gaps = 110/625 (17%)
Query: 761 KPTTDLVSSSSATTK------PDIPSSKVQS---QAEEKTTPPLKTDSAKPSQSFPPTGE 811
KP D+V + A K ++P+ + + QA+ + +T +AKP S P
Sbjct: 141 KPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTT 200
Query: 812 KVSPFDSKAIPRPASDS-KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKP 870
+ S P+P + HP P+ Q PV P+ QT P +P
Sbjct: 201 QASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT-PVMTVVPPQPLQTPPPVPPQPQP 259
Query: 871 MPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930
P +P P P P P ++ K + R+ + D P+ P E T K
Sbjct: 260 PPAPAPQPVQSHPPIIAATPQPVKTKKGVK--RKADTTTPTTIDPIHEPPSLPPEPKTTK 317
Query: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990
L GQ +++ P +PP P Q PAP
Sbjct: 318 L------------------GQ------------RRESSRPVKPPKKDVP---DSQQHPAP 344
Query: 991 AKSIPVKKETKAPAAEKLEPKAEQA-----PTVKRTETEKKPPPIKDSKSLTAEP-QKAV 1044
KS V ++ K + E A++ P K + E + D + P +
Sbjct: 345 EKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEAL--GLHDYCDIIKHPMDMST 402
Query: 1045 LPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
+ +KLE +D F + + N +NP H
Sbjct: 403 IKSKLEARE----------------YRDAQEFG--ADVRLMFSNCYKYNPPDHEVV---- 440
Query: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
A++ +L D+ +M A P PV SS AVPP K+V
Sbjct: 441 ---------AMARKLQDVFEMRFAKM-PDEPEEPVVAVSS---PAVPPPTKVVAPPSSSD 487
Query: 1165 KTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASAL-QEKKPLPEEKKLIPE 1223
+ + + E+ + + QE+ K ++ +AL Q ++ P++K+ +
Sbjct: 488 SSSDSSSDSDSSTDDSEEERAQRLA---ELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK 544
Query: 1224 EEKIRSEEKKPLLEE------KKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE 1277
E+K ++K +EE K+P P+ K + ++ +++ + E + E
Sbjct: 545 EKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEE 604
Query: 1278 GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPG-- 1335
+ P + +E +Q + LP ++ + I+ + + PD++E
Sbjct: 605 DKCKPMSYEEKRQLSLDINKLPG-------EKLGRVVHIIQSREPSLKNSNPDEIEIDFE 657
Query: 1336 --KEKTEKEDDKSDTSSSQQPKSPQ 1358
K T +E ++ TS ++ + PQ
Sbjct: 658 TLKPSTLRELERYVTSCLRKKRKPQ 682
Score = 51.2 bits (121), Expect = 3e-05
Identities = 47/174 (27%), Positives = 71/174 (40%), Gaps = 23/174 (13%)
Query: 427 LQSPAKAPGPTKTPVQQPGPGKIP--AQQAGPGKTSAQQTGPTKPPSQL---PGPAKPP- 480
+Q+ + G +T +PG +P Q + P +T Q P PP Q P PA P
Sbjct: 174 VQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQ--PNPPPVQATPHPFPAVTPD 231
Query: 481 -----------PQQPGPAKPP-PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528
P QP PP P QP P+ QP + PP P ++ K
Sbjct: 232 LIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
Query: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS-PSAKQPPS 581
+ P + P + PS P ++TK + S +P++PP P ++Q P+
Sbjct: 292 ADTTTPTTIDPIHEPPS--LPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPA 343
Score = 50.1 bits (118), Expect = 6e-05
Identities = 48/179 (26%), Positives = 65/179 (36%), Gaps = 14/179 (7%)
Query: 316 AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375
A+ G + + G AKP T + P T P PP P P PA P
Sbjct: 176 AKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATP-HPF-PAVTP--D 231
Query: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ-----VGTPKPLAQQPGLQSP 430
+ P P+ L PP V P P PA P Q TP+P+ + G++
Sbjct: 232 LIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
Query: 431 AKAPGPTK-TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
A PT P+ +P P P + + + P KPP + Q P P K
Sbjct: 292 ADTTTPTTIDPIHEP-PSLPPEPKTTKLGQRRESSRPVKPPKK---DVPDSQQHPAPEK 346
Score = 47.4 bits (111), Expect = 4e-04
Identities = 42/147 (28%), Positives = 55/147 (37%), Gaps = 17/147 (11%)
Query: 452 QQAGPGKTSAQQTGPTKP-----PSQLPGPAKPPPQQPGPAKPPPQ---QPGSAKPPS-- 501
Q G G+ ++TG KP P+ P Q P P PP Q P A P
Sbjct: 175 QAKGRGR-GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLI 233
Query: 502 -QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
Q P T PPQ P P QP P+ QP + P +P ++ K +
Sbjct: 234 VQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKAD 293
Query: 561 TGSGKPLQPPTVSPSAKQPPSQGLPKT 587
T + P T+ P + P PKT
Sbjct: 294 TTT-----PTTIDPIHEPPSLPPEPKT 315
Score = 46.6 bits (109), Expect = 6e-04
Identities = 120/597 (20%), Positives = 213/597 (35%), Gaps = 93/597 (15%)
Query: 1241 PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQP---QTKMEG 1297
PT E + ++ +AK ++ K V + P+T P Q
Sbjct: 165 PTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHP 224
Query: 1298 LPSGTPQSL---------PKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDT 1348
P+ TP + P + +T + QPQPP P V+
Sbjct: 225 FPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQ--------SHPPIIA 276
Query: 1349 SSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSF-----SQESSP 1403
++ Q K+ +G+ ++ + P +P + K G +++S ++ P
Sbjct: 277 ATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336
Query: 1404 SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQE-----------KT 1452
S A +S+ +S S + E KK + +P D E K
Sbjct: 337 DSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKH 396
Query: 1453 QSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHK-----EKSEFVDDITTRR 1507
T++ + E +++QE D S + DH+ K + V ++ +
Sbjct: 397 PMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 456
Query: 1508 EPYDSVEESSESENSPV--PQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSA 1565
P D EE + +SP P K SS S DS S ++ + E A
Sbjct: 457 MP-DEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSE-------EERA 508
Query: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL-----TRKSSTSID 1620
A E + + QL +S +++ K++ K K + KH+R +KS
Sbjct: 509 QRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP 568
Query: 1621 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEE--LVVTGGGGLRRFKTIELNSTIAD 1678
+ + + + E +K + + ESEE +R ++++N +
Sbjct: 569 PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGE 628
Query: 1679 K--------YSAESSQKKTSLYFDEEPELEMESLTDS--------------PEDRSRGE- 1715
K S E S K ++ +E E++ E+L S + + + E
Sbjct: 629 KLGRVVHIIQSREPSLKNSN---PDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEK 685
Query: 1716 -----GSSSLHASSFTPGTSPTSVSSLD-EDSDSS---PSHKKGESKQQRKARHRPH 1763
GSS + S + S + SS D EDS++ S KKG +++K H H
Sbjct: 686 VDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHH 742
Score = 44.7 bits (104), Expect = 0.002
Identities = 45/154 (29%), Positives = 60/154 (38%), Gaps = 28/154 (18%)
Query: 2380 SPSVSSLPAKP-RPFFRSSSLDISAQPPPPPPPPPPPPPPP-PPPPPPPLPPPTSPKPTI 2437
S ++LP KP RP S +L Q P P PP PP PP PP TS + +
Sbjct: 874 SNRAAALPPKPARPPAVSPAL---TQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQL 930
Query: 2438 LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGL 2497
++ V P TPL LP ++ + PPP+PP P PS
Sbjct: 931 YLQQLQKVQPP----TPL-----------------LPSVKVQSQPPPPLPPPPH--PSVQ 967
Query: 2498 VFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHP 2531
+ P PP P+P Q +P + P
Sbjct: 968 QQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQP 1001
Score = 44.3 bits (103), Expect = 0.003
Identities = 66/298 (22%), Positives = 117/298 (39%), Gaps = 23/298 (7%)
Query: 1695 EEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQ 1754
EEP + + S P + SSS +S +S S SS D DS+ + + E ++
Sbjct: 462 EEPVVAVSSPAVPPPTKVVAPPSSSDSSSD----SSSDSDSSTD-DSEEERAQRLAELQE 516
Query: 1755 QRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDEL 1814
Q KA H L ++ +++E + +K+++ E+ +RK +++KK K +
Sbjct: 517 QLKAVHEQLAALSQPQQNKPKKKE---------KDKKEKKKEKHKRKEEVEENKKSKAKE 567
Query: 1815 RAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISP 1874
++ ++ + SN+S E A + E EE + Y + + ++
Sbjct: 568 PPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPG 627
Query: 1875 EKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAA 1934
EK+ V + + S DE I + L+ E + K K P A
Sbjct: 628 EKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRK----PQA 683
Query: 1935 NERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQKGREQK 1992
+ D + + G E ES E + + S D T ++ GREQK
Sbjct: 684 EKVDVIAGSSKMKGFSSSES---ESSSESSSSDSEDSE--TEMAPKSKKKGHPGREQK 736
Score = 43.5 bits (101), Expect = 0.005
Identities = 61/288 (21%), Positives = 110/288 (38%), Gaps = 42/288 (14%)
Query: 3579 QYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPL---SPGKA 3635
Q L+ SPP+ +P E+ +S ++ V + SP + P SP P K
Sbjct: 1077 QSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKH 1136
Query: 3636 LESAFVPYEKPL-----PDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPK-PLSPTA 3689
ES P P P D+ + P+ PP +P K Q +PK P++P
Sbjct: 1137 PESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQ----EPKTPVAPKK 1192
Query: 3690 DESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRR 3749
D + + G+ + + P P + + S F +R
Sbjct: 1193 DLKIK------------------NMGSWASLVQKHPTTPSSTAKSSSDS-FEQFRRAARE 1233
Query: 3750 RICRTNTMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRK 3809
+ R K L+ + + E+E +LR+++ E+E ++ R E RR+
Sbjct: 1234 K------EEREKALK---AQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEA-RRRQ 1283
Query: 3810 EALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERPR 3857
E ++R+++++ Q A + SS + ++ Q + R R
Sbjct: 1284 EQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKR 1331
Score = 37.0 bits (84), Expect = 0.51
Identities = 37/124 (29%), Positives = 51/124 (41%), Gaps = 27/124 (21%)
Query: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQD---------GTPKSISSQQPEKIKSQ--P 251
P + PP Q P P+P Q P P Q TP+ + +++ K K+
Sbjct: 237 PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTT 296
Query: 252 PGTGKPI-QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ-P 309
P T PI + P+ P+ KL +R++SRP VKP P P QQ P
Sbjct: 297 PTTIDPIHEPPSLPPEPKTTKLGQRRESSRP------------VKP--PKKDVPDSQQHP 342
Query: 310 TPGK 313
P K
Sbjct: 343 APEK 346
Score = 35.0 bits (79), Expect = 1.9
Identities = 36/111 (32%), Positives = 48/111 (43%), Gaps = 4/111 (3%)
Query: 3208 DKQQQQLDLERELLELEK-IKQQRFAEELEWER--QEIQRFREQEKIMVQ-KKLEELQSM 3263
D +Q RE E EK +K Q E E ER QE R RE E + Q ++ E
Sbjct: 1222 DSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARR 1281
Query: 3264 KQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQ 3314
+Q QQ +E+Q Q + +A Q Q Q L QQ E + R+
Sbjct: 1282 RQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKRE 1332
Score = 34.7 bits (78), Expect = 2.5
Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 8/137 (5%)
Query: 3834 MSDSEVSSTRPTRIESQHGIER-PRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSS 3892
+ D E + T ++ Q +++ + P T + Q+Q L PP P Q Q
Sbjct: 913 LEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQ 972
Query: 3893 --PALPTQAPTSYTQQSHFEQQTLYHQQVSPYQT---QPTFQAVATMSFTPQVQPTPTPQ 3947
P P P QQ H H Q + T QP P Q P PQ
Sbjct: 973 QPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQ 1032
Query: 3948 PSYQLPSQMMVIQQKPR 3964
P+ P Q++ PR
Sbjct: 1033 PA--KPQQVIQHHHSPR 1047
Score = 33.9 bits (76), Expect = 4.3
Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 11/88 (12%)
Query: 1746 SHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQ------- 1798
+ K+ E +Q + R R L + EE R+E++ + QE+Q++ +QQ
Sbjct: 1248 AEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAA 1307
Query: 1799 ---QRKSSSKKSKKDKD-ELRAQRRRER 1822
Q +SS +S D+ EL +R +ER
Sbjct: 1308 ATPQAQSSQPQSMLDQQRELARKREQER 1335
Score = 32.7 bits (73), Expect = 9.6
Identities = 24/125 (19%), Positives = 59/125 (47%), Gaps = 10/125 (8%)
Query: 1729 TSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKE 1788
T+P+S + DS E +++ KA L + +E+E+ R +E ++
Sbjct: 1211 TTPSSTAKSSSDSFEQFRRAAREKEEREKA--------LKAQAEHAEKEKERLRQERMRS 1262
Query: 1789 QEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEM 1848
+E + +EQ +R + +++++ +++ + QR+ ++ + + A+P + Q M
Sbjct: 1263 REDEDALEQARR--AHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSM 1320
Query: 1849 EELHR 1853
+ R
Sbjct: 1321 LDQQR 1325
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 116 bits (291), Expect = 5e-25
Identities = 213/869 (24%), Positives = 295/869 (33%), Gaps = 138/869 (15%)
Query: 205 GIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG---------TG 255
G P +P+ G G PL P I + P I+ +P G T
Sbjct: 311 GAASAPTGTPSGQPLAVAPGLGSSPLVP--APNVILHRTPTPIQPKPAGVLPPKLYQLTP 368
Query: 256 KPIQ--GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS-LPSPSKPPIQQPTPG 312
KP G T T Q + LP Q A + T A G++V S P+P+ +Q
Sbjct: 369 KPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPA---LQANVFK 425
Query: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP 372
+PPA G A PP P L+KP++ + + PAQ + P +
Sbjct: 426 QPPATTTG--------AAPPQPPGALSKPMSVHL------LNQGSSIVIPAQHMLPGQNQ 471
Query: 373 AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
G+ P+ + P + A P VG Q A P T P+ L P
Sbjct: 472 FLLPGA--PAVQLP-QQLSALPANVG---GQILAAAAPHTGGQLIANPILTNQNLAGPLS 525
Query: 433 APGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQ 492
PV P G A Q + P L + P QP PA P
Sbjct: 526 LG-----PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAAT 580
Query: 493 Q--PGSAKPPSQ-----------QPGSTKPPPQQPGPA---KPSPQQPGSTKPPSQQPGS 536
G PPS QP + + P +P+PQ P + P G
Sbjct: 581 TVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPL-GL 639
Query: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ---GLPKTICPLCN 593
+P AQQP P P+ Q + P + T P SP P + G P + P
Sbjct: 640 QQPQAQQP-PQAPTPQAAAPPQATT--------PQPSPGLASSPEKIVLGQPPSATPTAI 690
Query: 594 TTE--LLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651
T+ L + +P++ + + PHL+ +
Sbjct: 691 LTQDSLQMFLPQERSQQPLSA------------EGPHLSV-----------------PAS 721
Query: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS---KAPEPKKPPPLVK 708
+ S+P P AP T + + PQ + AP+ + K P P P L
Sbjct: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH 781
Query: 709 QPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVS 768
Q L SP + P S PP P S P P P PT +
Sbjct: 782 QAPLGDSPHLPSPHPTRPPS----RPPSRPQSVSRPPSEPPL--HPCPPPQAPPTLPGIF 835
Query: 769 SSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDS 828
P+S A PPL+ S P PP S A+ + S
Sbjct: 836 VIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETS 895
Query: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK-GSPTPPGPRPTAGQ 887
+ P PS Q Q P Q P K+ T P P +P+ +P PP PR
Sbjct: 896 SRLPAPTPSD---FQLQFPPSQ---GPHKSPT---PPPTLHLVPEPAAPPPPPPRTFQMV 946
Query: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKS--QPTTPQETVTGKLFGFGASIFSQASNL 945
T P P P+P+ RF I K+ P PQ + + G AS L
Sbjct: 947 TTPFP-ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTS-----LGPLTSPAASVL 1000
Query: 946 ISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA 1005
+S G P AP APAP+ P + G P A A ++P KA ++
Sbjct: 1001 VS-----GQAPSGTPTAP-SHAPAPA-PMAATGLPPLLPAENKAFASNLPTLNVAKAASS 1053
Query: 1006 EKLEPKAEQAPTVKRTETEKKPPPIKDSK 1034
+P Q + + KKPP ++ SK
Sbjct: 1054 GPGKPSGLQYES--KLSGLKKPPTLQPSK 1080
Score = 103 bits (256), Expect = 6e-21
Identities = 193/837 (23%), Positives = 263/837 (31%), Gaps = 160/837 (19%)
Query: 320 GHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSE 379
G+ S GP++P S P K TT G A + TG+
Sbjct: 261 GYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGT- 319
Query: 380 KPSSEQPGPKALAQPPGVGKTPA---------QQPGPAKPPTQQVGTPKPLAQQPGLQSP 430
P + LA PG+G +P + P P +P V PK P +P
Sbjct: 320 ------PSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAP 373
Query: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTS---AQQTGPTKPPSQLPGPA-------KPP 480
A A T Q PG +P Q P + A + G S P PA +PP
Sbjct: 374 AGA-----TLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPP 428
Query: 481 PQQPGPAKPPPQQPGSAKPPSQ-----QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535
G A PPQ PG+ P Q S P Q P + PG+ P
Sbjct: 429 ATTTGAA--PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA-------PA 479
Query: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595
P PA Q TG P + + P S G ++
Sbjct: 480 VQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSA 539
Query: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
+L P + P L QM +L P S
Sbjct: 540 HILSAAPIQVG-------------------QPALF----------QMPVSLAAGSLPTQS 570
Query: 656 SPQPKLKTAPVTTT---------SAVSKSSPQPQQTSPKKDAAPKQD----LSKAPEPKK 702
P P P TT SAV+ + P AA + L+ P P+
Sbjct: 571 QPAP---AGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQA 627
Query: 703 PPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPK------EPSVPSEQDKAPVADDKPKQ 756
PP V P G +A+QPP+A + APP+ P + S +K + Q
Sbjct: 628 PPA-VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLG-----Q 681
Query: 757 PKMVKPTTDLVSSSSATTKPDIPSSK-VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP 815
P PT L S P S + + ++ + P SA P P V+
Sbjct: 682 PPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAK 741
Query: 816 F--------DSKAIPRPA--------------SDSKIISHPGPSSESKGQKQVDPVQKKE 853
DS+A P PA S S + H P +S P +
Sbjct: 742 GAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPS 801
Query: 854 EPKKAQTKMSPKPDAKPM-----PKGSPTPPG------------PRPTAGQTVPTPQQSP 896
P +S P P+ P+ PT PG P T P P Q P
Sbjct: 802 RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPP 861
Query: 897 -KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL-ISTAGQPGP 954
+PQ Q G + AP P++ V S+ + GP
Sbjct: 862 LRPQSQPPE-----GPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGP 916
Query: 955 HSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKET-----KAPAAEKLE 1009
H P + P P+ PP PP T Q P ++P K + P+ L+
Sbjct: 917 HKSPTPPPTLHLVPEPAAPPP---PPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQ 973
Query: 1010 PKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTEL 1066
KA AP +T T P + L + + PT +P P P+ T L
Sbjct: 974 NKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAP---APMAATGL 1027
Score = 99.4 bits (246), Expect = 8e-20
Identities = 208/922 (22%), Positives = 307/922 (33%), Gaps = 132/922 (14%)
Query: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT 262
P G+ +P QQ P P P+ P + Q P + PEKI P P+
Sbjct: 636 PLGLQQPQAQQPPQAPTPQAAAPPQATTPQ---PSPGLASSPEKIVLGQP--------PS 684
Query: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGE--SVKPSLPSPSKPPIQQPTPGKPPAQQPG 320
TP + LQ + +++Q G SV S+ + PP Q P P P A+ G
Sbjct: 685 ATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAG 744
Query: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
GP P +Q S P +K P + P PLG + +
Sbjct: 745 L-----GPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP 799
Query: 381 PSSEQPGPKALAQPPGVGKTPAQQ-PGPAKPPT--------QQVGTPKPLAQQPGLQSPA 431
PS P+++++PP + P P P PPT Q+G P P A P +P
Sbjct: 800 PSRPPSRPQSVSRPPS--EPPLHPCPPPQAPPTLPGIFVIQNQLGVPPP-ASNPAPTAPG 856
Query: 432 KAPGPTKTPVQQPGPGKIP-AQQAGPGKTSAQQTGPTKPPSQLPGPAKP------PPQQP 484
P P P QP G +P A P TS+ ++ S+LP P PP Q
Sbjct: 857 P-PQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQ- 914
Query: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQ-------PGPAKPSPQQ--PGSTKPPS---- 531
GP K P P P +P + PPP + P PA P P+ + PS
Sbjct: 915 GPHKSPTPPPTLHLVP--EPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIIL 972
Query: 532 QQPGSAKPSAQQPSPA---KPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Q P+A Q S + S S Q SG P P+ +P+ + GLP +
Sbjct: 973 QNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTP-TAPSHAPAPAPMAATGLPPLL 1031
Query: 589 ----------CPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCL 638
P N + P K + L G P L KE C
Sbjct: 1032 PAENKAFASNLPTLNVAKAASSGPGKPSGLQYES------KLSGLKKPPTLQPSKE-ACF 1084
Query: 639 NCQMKRALGGDLAPVPSSPQPKLKTA-----PVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
+ + G L P + P + A P S + + + Q
Sbjct: 1085 LEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQL 1144
Query: 694 LSKAPEP-KKPPPLVKQPTLHGSPSAK----------------------AKQPPE----- 725
L + K L+ + + SPSA+ AK+ P+
Sbjct: 1145 LKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSS 1204
Query: 726 ADSLSKP--APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783
+ SL P A + +P + A QP PT ++ A P + ++
Sbjct: 1205 SRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARA 1264
Query: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDS-KAIPRPASDSKIISHPGPSSESKG 842
S ++ S + P P + +A R KI G S+
Sbjct: 1265 SSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAG-LSKVVH 1323
Query: 843 QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902
+DPV + P A K++ P P PP P P GQ T P P
Sbjct: 1324 NTALDPVH-QPPPPPATLKVAEPP---------PRPPPPPPPTGQMNGTVDH-PPPAAPE 1372
Query: 903 RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGA 962
R+ + AP ++T + G GA + A + P P +
Sbjct: 1373 RK------PLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATS 1426
Query: 963 PMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTE 1022
+ + A + Q K P A A + +AP + + ++P V +
Sbjct: 1427 GLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQAS 1486
Query: 1023 TEKKPPPIKDSKSLTAEPQKAV 1044
P +LT Q A+
Sbjct: 1487 FSSDSP---QDDTLTEHLQSAI 1505
Score = 97.4 bits (241), Expect = 3e-19
Identities = 182/735 (24%), Positives = 239/735 (32%), Gaps = 167/735 (22%)
Query: 200 QGKPEGIIKPPLQQQPPKP-------IPKQQGPGRDPLQQDGTPKSISSQQPEK------ 246
Q KP G++ P L Q PKP + Q PG P QQ P++++ K
Sbjct: 352 QPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALP-QQPKAPQNLTFMAAGKAGQNVV 410
Query: 247 ------------IKSQPPGT------------------------GKPIQGPTQ------- 263
+ QPP T G I P Q
Sbjct: 411 LSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQN 470
Query: 264 ---TPQTDHAKLPLQRD------------ASRPQTKQADIVRGESVKPSLPSP-SKPPIQ 307
P +LP Q A+ P T I +L P S P+
Sbjct: 471 QFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVL 530
Query: 308 QPTPGKPPA---QQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP--PGTTKPP 362
P G A + QP + P + + P QP P G T PP
Sbjct: 531 APHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPP 590
Query: 363 A------QPLGPAKP--PAQQTGSEKP-SSEQPGPKA-----LAQPPGVGKTPAQQPGPA 408
+ P G +P PA TG P + QP P+A P G+ + AQQP P
Sbjct: 591 SAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQP-PQ 649
Query: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA--------QQAGPGKTS 460
P Q P+ QP SP A P K + QP P P Q P + S
Sbjct: 650 APTPQAAAPPQATTPQP---SPGLASSPEKIVLGQP-PSATPTAILTQDSLQMFLPQERS 705
Query: 461 AQQTGPTKPPSQLPG----PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516
Q P +P A PP Q P PA P + G S P PQ P
Sbjct: 706 QQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAA 765
Query: 517 AK-PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPS 575
A P S P Q P P P P +P ++ ++P S + +PP+ P
Sbjct: 766 APLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVS------RPPSEPPL 819
Query: 576 AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEW 635
PP Q P P + L VP A+ T P P ++
Sbjct: 820 HPCPPPQAPP--TLPGIFVIQNQLGVPPPASNPAPTA------------PGPPQPPLR-- 863
Query: 636 LCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLS 695
+ G L P P P P ++ V ++S S P P + + P Q
Sbjct: 864 -----PQSQPPEGPLPPAPHLP-PSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPH 917
Query: 696 KAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSK-----PAPPKEPS-------VPSE 743
K+P P PTLH P A PP + PA P+ + VPS
Sbjct: 918 KSPTP--------PPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSG 969
Query: 744 ---QDKAPVADDKPKQPKMVKPTTD-----LVSSSSATTKPDIPS-SKVQSQAEEKTTPP 794
Q+KA A P+ + P T LVS + + P PS + + PP
Sbjct: 970 IILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPP 1029
Query: 795 LKTDSAKPSQSFPPT 809
L K S PT
Sbjct: 1030 LLPAENKAFASNLPT 1044
Score = 59.3 bits (142), Expect = 1e-07
Identities = 91/382 (23%), Positives = 127/382 (33%), Gaps = 43/382 (11%)
Query: 802 PSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG----PSSESKGQKQVDPVQKKEEPKK 857
P+QS P + + + P S +++ P P++ + + PV + +
Sbjct: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQ 626
Query: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDA-P 916
A P + P+P G P +P PTPQ + PQ + + S L S +
Sbjct: 627 A-----PPAVSTPLPLGLQQPQAQQPPQA---PTPQAAAPPQATTPQPSPGLASSPEKIV 678
Query: 917 KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTS 976
QP P T T L +F GPH S P + + AP P+Q P
Sbjct: 679 LGQP--PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL-SVPASVIVSAPPPAQDPAP 735
Query: 977 Q---------GPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP 1027
GP QA PAPA IP K P QAP P
Sbjct: 736 ATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS-P 794
Query: 1028 PPIKDSKSLTAEPQKAVLPTK---LEKSPKPES--TCPLCKTELNIGSKDPPNFNTCTEC 1082
P + + PQ P L P P++ T P N PP N
Sbjct: 795 HPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTA 854
Query: 1083 --------KNQVCNLCG-FNPTPHL--TEIQEWLCLNCQTQRAISGQL-GDIRKMPPAPS 1130
+ Q G P PHL + + + +T + D + P
Sbjct: 855 PGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQ 914
Query: 1131 GPKASPMPVPTESSSQKTAVPP 1152
GP SP P PT + A PP
Sbjct: 915 GPHKSPTPPPTLHLVPEPAAPP 936
Score = 56.2 bits (134), Expect = 8e-07
Identities = 86/368 (23%), Positives = 128/368 (34%), Gaps = 53/368 (14%)
Query: 225 PGRDPLQQD--GTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ 282
PG PL G P K+ + G G +P A+ +S
Sbjct: 1222 PGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGG-------SPSVTWARASSSLSSSSSS 1274
Query: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL 342
+ A + + P +PS ++PPI+ +S+ G Q +GL+K +
Sbjct: 1275 SSAASSLDADEDGP-MPSRNRPPIKTY-----------EARSRIGLKLKIKQEAGLSKVV 1322
Query: 343 AQQP-GTVKPPVQPPGTTK---PPAQPLGPAKPPAQQTGS-EKPSSEQPGPKALAQPPGV 397
V P PP T K PP +P P P Q G+ + P P K L P
Sbjct: 1323 HNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHC 1382
Query: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
+ P + K + VG P P ++ +P P V + G I ++
Sbjct: 1383 PRLPLR-----KTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLI--RELAAV 1435
Query: 458 KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPA 517
+ Q PP P PA Q G P + PG PP+++ S P Q +
Sbjct: 1436 EDELYQRMLKGPP---PEPAASAAQ--GTGDPDWEAPGL--PPAKRRKSESPDVDQASFS 1488
Query: 518 KPSPQQPGSTKPPSQQPGS----AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
SPQ T+ S + + P+P+ P A +G P PP +
Sbjct: 1489 SDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHA---------ASAGTPASPPPLH 1539
Query: 574 PSAKQPPS 581
PPS
Sbjct: 1540 RPEAYPPS 1547
Score = 54.3 bits (129), Expect = 3e-06
Identities = 74/320 (23%), Positives = 115/320 (35%), Gaps = 51/320 (15%)
Query: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPP- 2430
PA+ +P ++ PA P S+ L + Q P PP P P PP P P
Sbjct: 608 PAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPS 667
Query: 2431 ----TSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG----LPVTRICTTA 2482
+SP+ +L + + + T L + + L + G +P + I +
Sbjct: 668 PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAP 727
Query: 2483 PPPVPPKPSS-IPSGLVFTHRPEPSKPPIAPKPVIPQL-----PTTTQKPTDIHPKPTGL 2536
PP P P++ + G + S+ AP P IP P + P+ H P G
Sbjct: 728 PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLG- 786
Query: 2537 SLTSSMTLNLVTSADYKLPSPTSPLS-PHSNKSS---------------PRFSKSLTETY 2580
S P PT P S P S S P+ +L +
Sbjct: 787 -----------DSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF 835
Query: 2581 VVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFY 2640
V+ ++ G P +S P P + +P +PP A +P SS +
Sbjct: 836 VI---QNQLGVPPPASNPAPTAPGPPQPPLRP--QSQPPEGPLPP--APHLPPSSTSS-A 887
Query: 2641 ISGALQTFSATPVTAPSSFQ 2660
++ + +T S P PS FQ
Sbjct: 888 VASSSETSSRLPAPTPSDFQ 907
Score = 50.4 bits (119), Expect = 4e-05
Identities = 71/281 (25%), Positives = 96/281 (34%), Gaps = 40/281 (14%)
Query: 2371 KPASQLP-SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPP 2429
+P S+ P P + P P F + L + PPP P P P PP PP P P
Sbjct: 812 RPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGV---PPPASNPAPTAPGPPQPPLRPQSQP 868
Query: 2430 PTSPKPTI--LPKKKLT--VASPVTTATPL-----FDAVTTLETTAVLRSNGLPVTRICT 2480
P P P LP + VAS T++ L D + + P +
Sbjct: 869 PEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHL 928
Query: 2481 TAPPPVPPKPSSIPSGLVFTHRPEPSKPPI-------APKPVIPQ-----LPTTTQKPTD 2528
P PP P +V T P +P P +I Q P Q T
Sbjct: 929 VPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTS 988
Query: 2529 IHP--KPTGLSLTSSMTLNLVTSADYKLPSPT-------SPLSPHSNKSSPRFSKSLTET 2579
+ P P L S + +A P+P PL P NK+ F+ +L
Sbjct: 989 LGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKA---FASNLPTL 1045
Query: 2580 YVVITLPSEPGTPTD---SSASQAITSWPLGSPSKDLVSVE 2617
V S PG P+ S + P PSK+ +E
Sbjct: 1046 NVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLE 1086
Score = 50.4 bits (119), Expect = 4e-05
Identities = 93/396 (23%), Positives = 134/396 (33%), Gaps = 69/396 (17%)
Query: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQP 215
F+ E A+ + K P + +S S + + + P P QP
Sbjct: 1179 FIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQP 1238
Query: 216 PKPIP-----KQQGPGRDP-LQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
P +P + G G P + S+SS S + P
Sbjct: 1239 PPHLPTKLVIRHGGAGGSPSVTWARASSSLSSS------SSSSSAASSLDADEDGPMPSR 1292
Query: 270 AKLPLQRDASRPQTKQADIVRGES-VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328
+ P++ +R + ++ E+ + + + + P+ QP P PPA + ++P P
Sbjct: 1293 NRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPP--PPATL---KVAEPPP 1347
Query: 329 AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGP 388
PP P P Q GTV P PP P +PLG A P + K E G
Sbjct: 1348 RPPPPPP-----PTGQMNGTVDHP--PPAA--PERKPLGTA-PHCPRLPLRKTYRENVGG 1397
Query: 389 KALAQ--PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ------QPGLQSPAKAPGPTKTP 440
+ P G + + P PAK G + LA Q L+ P P P +
Sbjct: 1398 PGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPP--PEPAASA 1455
Query: 441 VQQPG------PGKIPAQ----------QAGPGKTSAQQTGPTK--------------PP 470
Q G PG PA+ QA S Q T+ P
Sbjct: 1456 AQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAP 1515
Query: 471 SQLPGPAKPPPQQPG-PAKPPPQQPGSAKPPSQQPG 505
+ P P+ P G PA PPP A PPS G
Sbjct: 1516 GRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNG 1551
Score = 49.7 bits (117), Expect = 8e-05
Identities = 33/107 (30%), Positives = 43/107 (40%), Gaps = 5/107 (4%)
Query: 2396 SSSLDISAQPPPPPPPPPPPPPPPPPPPPPP----LPPPTSPKPTILPKKKLTVASPVTT 2451
+++LD QPPPPP PPP PPPPPP + P P++K +P
Sbjct: 1324 NTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCP 1383
Query: 2452 ATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLV 2498
PL G P R +P P+P K SGL+
Sbjct: 1384 RLPLRKTYRE-NVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLI 1429
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 112 bits (280), Expect = 9e-24
Identities = 158/642 (24%), Positives = 214/642 (33%), Gaps = 121/642 (18%)
Query: 103 GRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTD--------LKEEHKSSMMP 154
GR QP RT+ + SPS S + S+ + +KEE S +
Sbjct: 33 GRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKS 92
Query: 155 G------FLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208
S+ SS K + + E++ + V + P+ I +
Sbjct: 93 NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQ 152
Query: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD 268
P P P QD S SS Q + +++QPP +Q PT
Sbjct: 153 DNRSTSPSIPSP-----------QDNESDSDSSAQQQMLQAQPPA----LQAPT------ 191
Query: 269 HAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328
G + PS P P Q PTPG P+ + P
Sbjct: 192 ----------------------GVTPAPSSAPPGTP--QLPTPGPTPSATAVPPQGSPTA 227
Query: 329 AKPPAQPSGLTKPLAQQPGTVKPPVQP--PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386
++ P QP T P+ P + P P + PP P P P TG S+ QP
Sbjct: 228 SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP-SPHPPLQPLTG----SAGQP 282
Query: 387 GPKALAQPPGVGKTPAQQPGP----AKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
+ AQPP G+ P PGP A P Q G P+P P S +AP T
Sbjct: 283 SAPSHAQPPLHGQGP---PGPHSLQAGPLLQHPGPPQPFGLPP-QASQGQAPLGTSPAAA 338
Query: 443 QPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS 501
P ++PA Q ++ Q P + P P P +P P P PQ P
Sbjct: 339 YPHTSLQLPASQ-----SALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPA------ 387
Query: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561
P + K PP GP+ P PP+ +P S+ + PS P Q P SQ
Sbjct: 388 --PQAHKHPPHLSGPS-PFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQ--LMPQSQP 442
Query: 562 GSGKPLQPP--TVSPSAKQPPSQGLPKTICPLCNTTELLLH--VPEKANFNTCTECQTTV 617
P QPP T S + PP+ P + + H VP T C +T
Sbjct: 443 LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTS 502
Query: 618 CSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSP 677
G + C A GG +A S P P ++ A SP
Sbjct: 503 TPPAGPGTSAQPP---------CSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESP 553
Query: 678 QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAK 719
P SP P P V H S SA+
Sbjct: 554 PPPPRSP-----------------SPEPTVVDTPSHASQSAR 578
Score = 99.4 bits (246), Expect = 8e-20
Identities = 164/707 (23%), Positives = 248/707 (35%), Gaps = 80/707 (11%)
Query: 212 QQQPPKPIPKQQGPGRDPLQQDG--TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
++QP P + P + ++ G +P + S+ + + K ++ +P +
Sbjct: 35 KKQPASP-DGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSN 93
Query: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
+ QR+ T++AD R S K S+P G+ + +++ P
Sbjct: 94 KR---QREKVASDTEEAD--RTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDP- 147
Query: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA-----QPLGPAKPPAQQTGSEKPSSE 384
K + Q + P + P + + Q + A+PPA Q P+
Sbjct: 148 ----------KDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQA----PTGV 193
Query: 385 QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQP 444
P P + PPG + P P P+ G+P +Q P AP P T +QQ
Sbjct: 194 TPAPSSA--PPGTPQLPTPGPTPSATAVPPQGSPTA-SQAPNQPQAPTAPVP-HTHIQQ- 248
Query: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQP 504
P P Q P P P L G A P P A+PP G P S Q
Sbjct: 249 APALHP--QRPPSPHPPPHPSPHPPLQPLTGSAGQP-SAPSHAQPPLHGQGPPGPHSLQA 305
Query: 505 GSTKPPPQQPGPAKP---SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561
G P Q PGP +P PQ P P +A P PA SA QS +P +
Sbjct: 306 G---PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE- 361
Query: 562 GSGKPLQP-PTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620
+PL P P P K PP+ +P+ P + L P + N + L
Sbjct: 362 ---QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPL 418
Query: 621 CGFN----PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLKTAPVTTTSAVSK 674
+ P+ H ++ L P+PSSP P L + S
Sbjct: 419 SSLSTHHPPSAHPPPLQ------------LMPQSQPLPSSPAQPPGLTQSQNLPPPPASH 466
Query: 675 SSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP---EADSLSK 731
Q +P+ A + P P PP T P A QPP A S
Sbjct: 467 PPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSA-QPPCSGAAASGGS 525
Query: 732 PAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKT 791
A +P+ Q K DD ++P+ P S S T D PS QS K
Sbjct: 526 IAGGSSCPLPTVQIKEEALDD-AEEPESPPPPPR--SPSPEPTVVDTPSHASQSARFYKH 582
Query: 792 TPPLKTDSAKPSQSFPP-TGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQ 850
A+ F P G K++ +AI + +++ + E + +K+ + +
Sbjct: 583 LDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERER 642
Query: 851 KKEEPKKAQTKMSPKPDAKPMPKGSPTPPG-------PRPTAGQTVP 890
++E + K S + + PG P PT VP
Sbjct: 643 EREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVP 689
Score = 62.4 bits (150), Expect = 1e-08
Identities = 134/612 (21%), Positives = 202/612 (33%), Gaps = 121/612 (19%)
Query: 671 AVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLS 730
+ S S P PQ D++ +Q + +A PP ++ PT G A + PP L
Sbjct: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQ-----PPALQAPT--GVTPAPSSAPPGTPQLP 208
Query: 731 KPAP-PKEPSVPSEQDKAPVADDKPKQPKM-VKPTTDLVSSSSATTKPDIPSSKVQSQAE 788
P P P +VP + +P A P QP+ P + P P S
Sbjct: 209 TPGPTPSATAVPPQG--SPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP-HPPPH 265
Query: 789 EKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPAS--DSKIISHPGPSSE------- 839
PPL+ + Q P+ + P + P P S ++ HPGP
Sbjct: 266 PSPHPPLQPLTGSAGQPSAPSHAQ-PPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA 324
Query: 840 SKGQKQVD-------PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892
S+GQ + P + P S +P P+ P PP P A + P
Sbjct: 325 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP-----PREQPLPPAP--LAMPHIKPP 377
Query: 893 QQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP 952
+P PQ AP++ P + G S FS +NL
Sbjct: 378 PTTPIPQ-------------LPAPQAHKHPPHLS--------GPSPFSMNANLPPPPALK 416
Query: 953 GPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKA 1012
S S P P P SQ P S+ PP +S + + L A
Sbjct: 417 PLSSLSTHHPPSAHPPPLQLMPQSQ-PLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVA 475
Query: 1013 EQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKT-ELNIGSK 1071
Q P + PPPI TCP T G+
Sbjct: 476 PQPPFAQHPFVPGGPPPI------------------------TPPTCPSTSTPPAGPGTS 511
Query: 1072 DPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSG 1131
P C+ ++ G + P L +Q I + D + P +P
Sbjct: 512 AQP---PCSGAAASGGSIAGGSSCP-LPTVQ------------IKEEALDDAEEPESPPP 555
Query: 1132 PKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTT 1191
P SP P PT + A + K ++ + A + P+
Sbjct: 556 PPRSPSPEPTVVDTPSHA-SQSARFYKHLDRGYNSCARTDLY-----------FMPLA-- 601
Query: 1192 DQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPE 1251
SKL K + A+++ K E+K EE+ R +EK+ E ++ + + +
Sbjct: 602 -----GSKLAKKREEAIEKAKREAEQK---AREEREREKEKEKEREREREREREAERAAK 653
Query: 1252 AKTSAPEEQKHD 1263
A +SA E + D
Sbjct: 654 ASSSAHEGRLSD 665
Score = 61.2 bits (147), Expect = 3e-08
Identities = 80/302 (26%), Positives = 105/302 (34%), Gaps = 72/302 (23%)
Query: 2377 PSGSPSVSSLPAKPR-PFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPP------ 2429
P GSP+ S P +P+ P I P P PP P PPP P P PPL P
Sbjct: 221 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAG 280
Query: 2430 -------------------------------PTSPKPTILPKKKLTVASPVTTATPLFDA 2458
P P+P LP + +P+ T+
Sbjct: 281 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYP 340
Query: 2459 VTTLETTAVLRSNGLPVTRICTTAPP---PVPPKPSSIPSGLVFTHRPEPSKPPIAPKPV 2515
T+L+ A + + + PP P+PP P ++P KPP P
Sbjct: 341 HTSLQLPA-------SQSALQSQQPPREQPLPPAPLAMPH----------IKPP--PTTP 381
Query: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSP-RFSK 2574
IPQLP H P LS S ++N A+ P PLS S P
Sbjct: 382 IPQLPA-----PQAHKHPPHLSGPSPFSMN----ANLPPPPALKPLSSLSTHHPPSAHPP 432
Query: 2575 SLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDL--VSVEPVFSVVPPVTAVEIP 2632
L LPS P P + SQ + P P L V+ +P F+ P V P
Sbjct: 433 PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP 492
Query: 2633 IS 2634
I+
Sbjct: 493 IT 494
Score = 60.8 bits (146), Expect = 3e-08
Identities = 99/381 (25%), Positives = 139/381 (36%), Gaps = 86/381 (22%)
Query: 753 KPKQPKM----VKPTTDLVSSSSATTKPDIPSSKVQSQAE--EKTTPPLKTDSAKPSQSF 806
+ KQP P + + SS + +S S+AE +K+ +K +++ P +S
Sbjct: 34 RKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSN 93
Query: 807 PPTGEKVSPFDSKA------------IPRP---------ASDSKIISHPGPS-------- 837
EKV+ +A I RP +SDS+ ++ G S
Sbjct: 94 KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQD 153
Query: 838 ---------------SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR 882
S+S Q +Q + +A T ++P P + P G+P P P
Sbjct: 154 NRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS--APPGTPQLPTPG 211
Query: 883 PTAGQTVPTPQQSPKP-----QEQSRRFSLNLGSITDAPKSQPTTPQ------------- 924
PT T PQ SP Q Q+ + I AP P P
Sbjct: 212 PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP 271
Query: 925 -ETVTGKLFGFGASIFSQASNLISTAGQPGPHS-QSGPGAPMKQAPAPSQPPTSQGPPKS 982
+ +TG S S A + G PGPHS Q+G P+ Q P P Q P P S
Sbjct: 272 LQPLTGS--AGQPSAPSHAQPPLHGQGPPGPHSLQAG---PLLQHPGPPQ-PFGLPPQAS 325
Query: 983 TGQAP--PAPAKSIP---VKKETKAPAAEKLEPKAEQ-APTVKRTETEKKPPPIKDSKSL 1036
GQAP +PA + P ++ A + +P EQ P KPPP L
Sbjct: 326 QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL 385
Query: 1037 TAEPQKAVLPTKLEKSPKPES 1057
A PQ P L P P S
Sbjct: 386 PA-PQAHKHPPHL-SGPSPFS 404
Score = 48.5 bits (114), Expect = 2e-04
Identities = 60/254 (23%), Positives = 82/254 (32%), Gaps = 39/254 (15%)
Query: 2365 ETFGQEKPASQ--LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP-----PP 2417
+ FG ASQ P G+ ++ P S S S QPP P PP P
Sbjct: 316 QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIK 375
Query: 2418 PPPPPPPPPLPPPTS--------------------PKPTILPKKKLTVASPVTTATPLFD 2457
PPP P P LP P + P P + P L+ P + P
Sbjct: 376 PPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQ 435
Query: 2458 AVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI----PSGLVFTHRPEPSKPPIAPK 2513
+ + + +T+ PPP P+ + P H P PP
Sbjct: 436 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 495
Query: 2514 PVIPQLPTTTQKP-TDIHPKPTGLSLT-------SSMTLNLVTSADYKLPSPTSPLSPHS 2565
P P T P T P +G + + SS L V + L P SP
Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP 555
Query: 2566 NKSSPRFSKSLTET 2579
SP ++ +T
Sbjct: 556 PPRSPSPEPTVVDT 569
Score = 44.3 bits (103), Expect = 0.003
Identities = 85/360 (23%), Positives = 127/360 (35%), Gaps = 71/360 (19%)
Query: 2251 APPDGRASADHIVISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGN 2310
A PDGR S + D+ SS + A T S D S+ + VKK+ K+
Sbjct: 39 ASPDGRTSPIN-----EDIRSS------GRNSPSAASTSSND---SKAETVKKSAKKVKE 84
Query: 2311 GIILEVLEAYRDKKEL-----EAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGE 2365
+ R ++++ EA+RT S ++T P+S P + + ++ S
Sbjct: 85 EASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNS----PSEGEGESSDSRSVN 140
Query: 2366 TFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQ--------------------P 2405
G P + S+ P+ P P S D SAQ P
Sbjct: 141 DEGSSDPKD---IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP 197
Query: 2406 PPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPV---------------- 2449
PP P P P P P +PP SP + P + +PV
Sbjct: 198 SSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRP 257
Query: 2450 TTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV----PPKPSSIPSGLVFTHRPEP 2505
+ P + S G P + A PP+ PP P S+ +G + H P
Sbjct: 258 PSPHPPPHPSPHPPLQPLTGSAGQPSAP--SHAQPPLHGQGPPGPHSLQAGPLLQHPGPP 315
Query: 2506 SKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLS-PH 2564
+ P+ Q P T P +P T L L +S + + P P +PL+ PH
Sbjct: 316 QPFGLPPQASQGQAPLGT-SPAAAYPH-TSLQLPASQSALQSQQPPREQPLPPAPLAMPH 373
Score = 39.7 bits (91), Expect = 0.078
Identities = 59/293 (20%), Positives = 98/293 (33%), Gaps = 38/293 (12%)
Query: 795 LKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD---SKIISHPGPSSESKGQKQVDPVQK 851
++T ++ S S +G K P P ++ S + P +S S + + V+K
Sbjct: 18 MRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKK 77
Query: 852 KEEPKKAQTKMSPKPDAKPMPK-GSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLG 910
+ K + K + + K S T R ++ +T P + S +
Sbjct: 78 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSR 137
Query: 911 SITDAPKSQPT--------------TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHS 956
S+ D S P +PQ+ + S A + A P +
Sbjct: 138 SVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDS--------DSSAQQQMLQAQPPALQA 189
Query: 957 QSG-PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015
+G AP P Q PT P +T P + + +AP A +QA
Sbjct: 190 PTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQA 249
Query: 1016 PTV--KRTETEKKPP---------PIKDSKSLTAEPQKAVLPTKLEKSPKPES 1057
P + +R + PP P+ S + P A P + P P S
Sbjct: 250 PALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS 302
Score = 38.9 bits (89), Expect = 0.13
Identities = 55/270 (20%), Positives = 100/270 (37%), Gaps = 42/270 (15%)
Query: 3705 TKGSQTMTSSGAQKKVKRT--LPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKI 3762
++GS + SG +K+ +P E+I + +++ S T S T + K+
Sbjct: 23 SRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKV 82
Query: 3763 LQDIDRELDLVERESAKLRKKQAELDE------EEKEIDAKLRYLE--------MGINRR 3808
++ L +R+ K+ E D + +EI E +N
Sbjct: 83 KEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE 142
Query: 3809 KEALLKEREKRERAYLQGVAEDRDYMSDSEVSS------TRPTRIESQHGIE-RPRTAPQ 3861
+ K+ ++ R+ + +D SDS+ S+ +P +++ G+ P +AP
Sbjct: 143 GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP 202
Query: 3862 TEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSP 3921
P T + + + P SP + P QAPT+ +H +Q H Q P
Sbjct: 203 GTPQLPTPGPTPSATAVPPQGSPTASQAPNQP----QAPTAPVPHTHIQQAPALHPQRPP 258
Query: 3922 YQTQPTFQAVATMSFTPQVQPTPTPQPSYQ 3951
+P P P+P P Q
Sbjct: 259 ---------------SPHPPPHPSPHPPLQ 273
Score = 34.3 bits (77), Expect = 3.3
Identities = 18/64 (28%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 1776 EEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIED 1835
E++ REE E KE+EK+RE +++R+ ++++ K R + + P ++ P +
Sbjct: 621 EQKAREEREREKEKEKERE-REREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFE 679
Query: 1836 ASPT 1839
PT
Sbjct: 680 PPPT 683
Score = 33.9 bits (76), Expect = 4.3
Identities = 29/132 (21%), Positives = 57/132 (43%), Gaps = 11/132 (8%)
Query: 1277 EGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGK 1336
+GR +P + + + S + K+ K +KE+ P + Q +
Sbjct: 42 DGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQ----R 97
Query: 1337 EKTEKEDDKSDTSSSQQPKSPQ-GLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKD 1395
EK + +++D +SS++ K+ + ++ +G SS + +D KDI D
Sbjct: 98 EKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDI------D 151
Query: 1396 SFSQESSPSSPS 1407
++ +SPS PS
Sbjct: 152 QDNRSTSPSIPS 163
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.125 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 241,817,005
Number of Sequences: 37866
Number of extensions: 15575482
Number of successful extensions: 365159
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1814
Number of HSP's successfully gapped in prelim test: 3693
Number of HSP's that attempted gapping in prelim test: 79620
Number of HSP's gapped (non-prelim): 134652
length of query: 5142
length of database: 18,247,518
effective HSP length: 124
effective length of query: 5018
effective length of database: 13,552,134
effective search space: 68004608412
effective search space used: 68004608412
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.