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Search of human proteins with 110227629
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110227629 translin-associated factor X interacting protein 1
[Homo sapiens]
(658 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110227629 translin-associated factor X interacting protein 1 ... 1315 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 50 9e-06
gi|55770834 centromere protein F [Homo sapiens] 49 2e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 48 3e-05
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 48 3e-05
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 47 4e-05
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 47 4e-05
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 47 7e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 45 2e-04
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 45 3e-04
gi|112420968 coiled-coil domain containing 158 [Homo sapiens] 44 4e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 44 4e-04
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 44 5e-04
gi|71061468 centromere protein E [Homo sapiens] 44 5e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 44 5e-04
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 44 5e-04
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens] 44 5e-04
gi|38045919 huntingtin interacting protein 1 [Homo sapiens] 44 6e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 43 8e-04
gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens] 43 8e-04
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 43 0.001
gi|110611218 ribosome binding protein 1 [Homo sapiens] 42 0.001
gi|110611220 ribosome binding protein 1 [Homo sapiens] 42 0.001
gi|112734867 retinitis pigmentosa GTPase regulator interacting p... 42 0.001
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 42 0.001
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 42 0.001
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 42 0.002
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 42 0.002
gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens] 42 0.002
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 42 0.002
>gi|110227629 translin-associated factor X interacting protein 1
[Homo sapiens]
Length = 658
Score = 1315 bits (3402), Expect = 0.0
Identities = 658/658 (100%), Positives = 658/658 (100%)
Query: 1 MGGHLSPWPTYTSGQTILQNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELL 60
MGGHLSPWPTYTSGQTILQNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELL
Sbjct: 1 MGGHLSPWPTYTSGQTILQNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELL 60
Query: 61 LLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEPLK 120
LLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEPLK
Sbjct: 61 LLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEPLK 120
Query: 121 AKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNL 180
AKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNL
Sbjct: 121 AKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNL 180
Query: 181 AEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTR 240
AEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTR
Sbjct: 181 AEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTR 240
Query: 241 TQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTL 300
TQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTL
Sbjct: 241 TQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTL 300
Query: 301 KERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGSG 360
KERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGSG
Sbjct: 301 KERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGSG 360
Query: 361 LLREKDFFPGLGYGEAIPAFLRFDGLVENKKPSKKDVVNLLKDAWKERLAEEQKETFPDF 420
LLREKDFFPGLGYGEAIPAFLRFDGLVENKKPSKKDVVNLLKDAWKERLAEEQKETFPDF
Sbjct: 361 LLREKDFFPGLGYGEAIPAFLRFDGLVENKKPSKKDVVNLLKDAWKERLAEEQKETFPDF 420
Query: 421 FFNFLEHRFGPSDAMAWAYTIFENIKIFHSNEVMSQFYAVLMGKRSENVYVTQKETVAQL 480
FFNFLEHRFGPSDAMAWAYTIFENIKIFHSNEVMSQFYAVLMGKRSENVYVTQKETVAQL
Sbjct: 421 FFNFLEHRFGPSDAMAWAYTIFENIKIFHSNEVMSQFYAVLMGKRSENVYVTQKETVAQL 480
Query: 481 LKEMTNADSQNEGLLTMEQFNTVLKSTFPLKTEEQIQELMEAGGWHPSSSNADLLNYRSL 540
LKEMTNADSQNEGLLTMEQFNTVLKSTFPLKTEEQIQELMEAGGWHPSSSNADLLNYRSL
Sbjct: 481 LKEMTNADSQNEGLLTMEQFNTVLKSTFPLKTEEQIQELMEAGGWHPSSSNADLLNYRSL 540
Query: 541 FMEDEEGQSEPFVQKLWEQYMDEKDEYLQQLKQELGIELHEEVTLPKLRGGLMTIDPSLD 600
FMEDEEGQSEPFVQKLWEQYMDEKDEYLQQLKQELGIELHEEVTLPKLRGGLMTIDPSLD
Sbjct: 541 FMEDEEGQSEPFVQKLWEQYMDEKDEYLQQLKQELGIELHEEVTLPKLRGGLMTIDPSLD 600
Query: 601 KQTVNTYMSQAFQLPESEMPEEGDEKEEAVVEILQTALERLQVIDIRRVGPREPEPAS 658
KQTVNTYMSQAFQLPESEMPEEGDEKEEAVVEILQTALERLQVIDIRRVGPREPEPAS
Sbjct: 601 KQTVNTYMSQAFQLPESEMPEEGDEKEEAVVEILQTALERLQVIDIRRVGPREPEPAS 658
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 49.7 bits (117), Expect = 9e-06
Identities = 56/235 (23%), Positives = 106/235 (45%), Gaps = 28/235 (11%)
Query: 103 EGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAE-EKYEISLLK--KEKMNLLKLI 159
E + E++ E + ++LV + ++ +++ + + E++L K KEK +
Sbjct: 920 EAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKV 979
Query: 160 DKKNEEKISLQSEVTKL---RKNLAEEYLHYLS----ERDACKILIADLNELRYQREDM- 211
+EE +L+ ++KL +K+L E + L E D LI +L Q +D+
Sbjct: 980 KNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLE 1039
Query: 212 -SLAQSPGIWGE---DPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKT 267
SL Q + + KL LKM+++ + M+L N K + + +++FE+ +
Sbjct: 1040 GSLEQEKKLRADLERAKRKLEGDLKMSQESI----MDLENDKQQIEEKLKKKEFELSQLQ 1095
Query: 268 NK---------DLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEI 313
K Q+++ L+A EE+ +E E L K+R EL+EI
Sbjct: 1096 AKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEI 1150
Score = 32.7 bits (73), Expect = 1.1
Identities = 60/281 (21%), Positives = 106/281 (37%), Gaps = 34/281 (12%)
Query: 50 ELENYLRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQ 109
EL + + ++ L+ T S Q L Q +E+ K + KNA L
Sbjct: 1290 ELSHRVEEKESLISQLTKSKQALTQQ---------LEELKRQMEEETKAKNAMAHALQSS 1340
Query: 110 R-------EKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLL---------KKEKM 153
R E+ + KA+L N + R KYE + KK+
Sbjct: 1341 RHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRT--KYETDAIQRTEELEEAKKKLA 1398
Query: 154 NLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSL 213
L+ ++ E S + + K ++ L E + + + A L++ + + D L
Sbjct: 1399 QRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDK-KQRNFDKVL 1457
Query: 214 AQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQE 273
A+ E +L A K +R T EL M+ + +VV + E + NK+LQE
Sbjct: 1458 AEWKQKLDESQAELEAAQKESRSLST----ELFKMRNAYEEVVDQ--LETLRRENKNLQE 1511
Query: 274 QLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQ 314
++ L E K + + +E+ L+E++
Sbjct: 1512 EISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVE 1552
Score = 30.8 bits (68), Expect = 4.1
Identities = 38/184 (20%), Positives = 82/184 (44%), Gaps = 25/184 (13%)
Query: 122 KLVTVNEDCNERILAMRAEEKYEISLLKKEKMN--LLKLIDKKNEEKISLQSEVTKLRKN 179
++ T+ ED R +E+ S +++++ ++ L+ +KN+ ++ +QSE L
Sbjct: 852 EMATMKEDFE------RTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMD- 904
Query: 180 LAEEYLHYLSERDACKILI-ADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDL 238
AEE L + KIL+ A + EL + E+ S +L +
Sbjct: 905 -AEERCEGLIK---SKILLEAKVKELTERLEEEEEMNS---------ELVAKKRNLEDKC 951
Query: 239 TRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMS 298
+ + ++++++ V ++ E K+L E++ L + ++ KE + L + H
Sbjct: 952 SSLKRDIDDLELTLTKV--EKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQ 1009
Query: 299 TLKE 302
TL +
Sbjct: 1010 TLDD 1013
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 48.5 bits (114), Expect = 2e-05
Identities = 65/284 (22%), Positives = 129/284 (45%), Gaps = 47/284 (16%)
Query: 95 LSSIKNAYEGMLAH-QREKIRALEPLKAK---LVTVNEDCNERILAMRAEEKY------- 143
L I +++E +L ++EK++ E L T ++ NER+ A+ +++
Sbjct: 2411 LEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQN 2470
Query: 144 ---EISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIAD 200
++ L+ EK LL+ +D+ I LQS V L + + E+ L ++D +
Sbjct: 2471 LSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEV-EDGKQKLEKKDE------E 2523
Query: 201 LNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRD 260
++ L+ Q +D E V ++ Q +EL N+ +
Sbjct: 2524 ISRLKNQIQDQ----------EQLVSKLSQVEGEHQLWKEQNLELRNLTVEL-----EQK 2568
Query: 261 FEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQR----- 315
++ + N LQ+ L+ L++SY+ + E E+ MS +++ ++ ++ E+QR
Sbjct: 2569 IQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEM 2628
Query: 316 ---TSTPRPDWTKCKDVVAGGPERWQMLAEGKNS-DQLVDVLLE 355
T+ + + + K+ +AG E +L E K+S DQL ++ LE
Sbjct: 2629 AQKTAELQEELSGEKNRLAG--ELQLLLEEIKSSKDQLKELTLE 2670
Score = 33.9 bits (76), Expect = 0.49
Identities = 74/338 (21%), Positives = 130/338 (38%), Gaps = 53/338 (15%)
Query: 18 LQNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQP- 76
L+ ++ CS D K+ ++H + L + E + L L+L +EL+ +
Sbjct: 563 LEKQRDCSQDLLKK----REHHIEQLNDK-LSKTEKESKALLSALELKKKEYEELKEEKT 617
Query: 77 ----YREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQR-------EKIRALEP------- 118
++ E + ++ K L S N E L Q+ E++R LE
Sbjct: 618 LFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSV 677
Query: 119 --------LKAKLVTVNEDCNERILAMRAEEKYEISLLKKEK---------MNLLKLIDK 161
L +K V V +++ M ++K E S K +K L ++
Sbjct: 678 EIRNLHNVLDSKSVEVE---TQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVED 734
Query: 162 KNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADL--NELRYQREDMSLAQSPGI 219
+ L +E+ + + + Y S RD K A L NE +QR ++ Q P +
Sbjct: 735 LEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNE-DHQRSLLAFDQQPAM 793
Query: 220 WGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRD-----FEMQEKTNKDLQEQ 274
+ M + + ++E + N + R D E Q++ N DLQ+Q
Sbjct: 794 HHSFANIIGEQGSMP-SERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQ 852
Query: 275 LDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQE 312
+ L E+ + Q+H S + E Q S+LQE
Sbjct: 853 CEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQE 890
Score = 30.8 bits (68), Expect = 4.1
Identities = 51/250 (20%), Positives = 103/250 (41%), Gaps = 67/250 (26%)
Query: 95 LSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEE------------K 142
LS KN G L E+I++ + +L N + + + M ++ +
Sbjct: 2639 LSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAE 2698
Query: 143 YEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLN 202
Y++ L + EK + L+D + ++ +Q+ Y L+ ++ C
Sbjct: 2699 YQLRLHEAEKKHQALLLDTNKQYEVEIQT------------YREKLTSKEEC-------- 2738
Query: 203 ELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQ---DLTRTQMELNNMKANFGDVVPRR 259
L Q+ ++ L +S +L +LK T Q +L +T+M+ N+K
Sbjct: 2739 -LSSQKLEIDLLKS------SKEELNNSLKATTQILEELKKTKMD--NLKY--------- 2780
Query: 260 DFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILM----QLHMSTLKER---------DQF 306
+K N+ Q ++ L S +++ +E EIL QL + K++ D+
Sbjct: 2781 -VNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDEL 2839
Query: 307 FSELQEIQRT 316
+E++E++ T
Sbjct: 2840 TTEIKELKET 2849
Score = 30.4 bits (67), Expect = 5.4
Identities = 31/143 (21%), Positives = 72/143 (50%), Gaps = 6/143 (4%)
Query: 151 EKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQRED 210
E + LL +I+ ++ + SL +E+ +L L + + +++ +AC L + EL+ + D
Sbjct: 1782 ENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSD 1841
Query: 211 MSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELN-NMKANFGDVVPRRDFEMQEKTNK 269
+S + + D +L ++ + + +M + + + + GD V + + +E+
Sbjct: 1842 LS--EKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERF-L 1898
Query: 270 DLQEQLDTLRASYEEVRKEHEIL 292
D++ +L +R+ E+ EHE L
Sbjct: 1899 DVENELSRIRS--EKASIEHEAL 1919
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 48.1 bits (113), Expect = 3e-05
Identities = 56/288 (19%), Positives = 126/288 (43%), Gaps = 33/288 (11%)
Query: 55 LRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTY-------KPLLSSIKNAYEGMLA 107
L +E ++L+ Q +L +++ E I +F T L+ +KN +E M+
Sbjct: 976 LEEEQIILE-----DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMIT 1030
Query: 108 HQREKIRA-------LEPLKAKLVTVNEDCNERILAMRA---EEKYEISLLKKEKMNLLK 157
E++R LE + KL + D +++I ++A E K +++ ++E L
Sbjct: 1031 DLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA 1090
Query: 158 LIDKKNEEKI-------SLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQRED 210
++++ +K L+S++++L+++L E + L +L L+ + ED
Sbjct: 1091 RVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150
Query: 211 M--SLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPR--RDFEMQEK 266
S A + + ++ + K ++ + ++ M+ V E ++
Sbjct: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210
Query: 267 TNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQ 314
+L++ TL E+ E ++L+Q + +R + ++LQE+Q
Sbjct: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQ 1258
Score = 43.5 bits (101), Expect = 6e-04
Identities = 75/362 (20%), Positives = 145/362 (40%), Gaps = 48/362 (13%)
Query: 33 GSCQQHPFRTAKPQYLEELENYLRKEL--LLLDLGTDSTQELRLQPYREIFEFFIEDFKT 90
G Q+H + A LE+ + L++EL LL+DL L+ ++ F+ + + KT
Sbjct: 1396 GLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT 1455
Query: 91 YKPLLSSIKNAYEGMLAHQREKI----RALEPL---KAKLVTVNEDCN---ERILAMRAE 140
+ ++ E + K RALE KA+L +N+ E +++ + +
Sbjct: 1456 ISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDD 1515
Query: 141 EKYEISLLKKEKMNLLKLIDKKNEEKISLQSEV-----TKLRKNLAEEYLHYLSERDAC- 194
+ L+K K L + +++ + L+ E+ KLR + + + ERD
Sbjct: 1516 VGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG 1575
Query: 195 ---------KILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMEL 245
K L+ + E+ + ED +S + A K DL + +
Sbjct: 1576 RDEQSEEKKKQLVRQVREMEAELEDERKQRSMAV---------AARKKLEMDLKDLEAHI 1626
Query: 246 NNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEV---RKEHEILMQLHMSTLKE 302
++ N + + + + KD +LD RAS EE+ KE+E ++ + + +
Sbjct: 1627 DSANKNRDEAI--KQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQ 1684
Query: 303 RDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNS-----DQLVDVLLEEI 357
+ + + +R + D + D +A + + E K QL + L EE
Sbjct: 1685 LQEELAAAERAKRQAQQERD--ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQ 1742
Query: 358 GS 359
G+
Sbjct: 1743 GN 1744
Score = 42.4 bits (98), Expect = 0.001
Identities = 69/340 (20%), Positives = 132/340 (38%), Gaps = 59/340 (17%)
Query: 19 QNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQPYR 78
+NR+ S + + +++ FR + EE ++ L K++ +T ++ +
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEE-EEAKHNLEKQI--------ATLHAQVADMK 1370
Query: 79 EIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRA---LEPLKAKLVTVNED------ 129
+ E + +T + + ++ EG+ EK+ A LE K +L +D
Sbjct: 1371 KKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Query: 130 ------CN---------------ERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKIS 168
CN + I A AEE+ +EK + + EE +
Sbjct: 1431 HQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAME 1490
Query: 169 LQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLT 228
++E+ +L K E +S +D + +L ++ +L Q +L
Sbjct: 1491 QKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL-----EKSKRALEQQVEEMKTQLEELE 1545
Query: 229 LALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKE 288
L+ T R ++ L MKA F + RD E E+ K L Q+ + A E+ RK+
Sbjct: 1546 DELQATEDAKLRLEVNLQAMKAQFERDLQGRD-EQSEEKKKQLVRQVREMEAELEDERKQ 1604
Query: 289 HEIL-------------MQLHM-STLKERDQFFSELQEIQ 314
+ ++ H+ S K RD+ +L+++Q
Sbjct: 1605 RSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQ 1644
Score = 35.8 bits (81), Expect = 0.13
Identities = 49/228 (21%), Positives = 94/228 (41%), Gaps = 26/228 (11%)
Query: 92 KPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKE 151
K L I + E + + E+ + L+ K K+ ++ E++ EE+ L+ E
Sbjct: 910 KQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQL----EEEESARQKLQLE 965
Query: 152 KMNLLKLIDKKNEEKISLQSEVTKLRK-------NLAEEYLHYLSERDACKILIADLNEL 204
K+ + K EE+I L+ + KL K +AE + E + K L +L
Sbjct: 966 KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSK----SLAKL 1021
Query: 205 RYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQ 264
+ + E M + E+ RQ+L +T+ +L + D + ++
Sbjct: 1022 KNKHEAMITDLEERLRREE---------KQRQELEKTRRKLEGDSTDLSDQIAELQAQIA 1072
Query: 265 EKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQE 312
E L ++ + L+A+ V +E + + ++E + SELQE
Sbjct: 1073 E-LKMQLAKKEEELQAALARV-EEEAAQKNMALKKIRELESQISELQE 1118
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 47.8 bits (112), Expect = 3e-05
Identities = 43/182 (23%), Positives = 86/182 (47%), Gaps = 20/182 (10%)
Query: 117 EPLKAKLVTVNEDCNERILAMRAEE------KYEISLLKKEKMNL---LKLIDKKNEEKI 167
E LKAK V++ ++ N+ IL ++AE+ + + L K K+ L +K + ++ EE+
Sbjct: 883 EELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEE 942
Query: 168 SLQSEVTKLRKNLAEEYLHYLSERDACKILI--ADLNELRYQREDMSLAQSPGIWGEDPV 225
+ SE+T + L +E E D + ++ ++ + + + +L + ED
Sbjct: 943 EINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDIS 1002
Query: 226 KLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEV 285
KL A K+ ++ +T +L+ + + K N L++Q+D L + E+
Sbjct: 1003 KLNRAAKVVQEAHQQTLDDLHMEEEKLSSL---------SKANLKLEQQVDELEGALEQE 1053
Query: 286 RK 287
RK
Sbjct: 1054 RK 1055
Score = 34.3 bits (77), Expect = 0.37
Identities = 67/314 (21%), Positives = 124/314 (39%), Gaps = 67/314 (21%)
Query: 73 RLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEP-----LKAKL---- 123
+LQ E EF E+ K + L+ KN L ++E + +E +K+K+
Sbjct: 870 QLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEA 929
Query: 124 --------VTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTK 175
V E+ N + A + + E LKKE +L ++ K +EK + + +V
Sbjct: 930 RVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKV-- 987
Query: 176 LRKNLAEEYLHYLSERDACKILIA----------DLNELRYQREDMSLAQSPGIWGEDPV 225
KNL EE + +L+E D K+ A L++L + E +S + E V
Sbjct: 988 --KNLTEE-VEFLNE-DISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQV 1043
Query: 226 -KLTLALKMTRQDLTRTQMELNNMKANF-----------------GDVVPRRDFEMQE-- 265
+L AL+ R+ + EL+ ++ N + + +++ E+ +
Sbjct: 1044 DELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMN 1103
Query: 266 --------------KTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQ 311
KT K+LQ Q+ L+ E R + + ++ L+
Sbjct: 1104 SKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLE 1163
Query: 312 EIQRTSTPRPDWTK 325
E+ +S + + TK
Sbjct: 1164 EVGGSSLAQLEITK 1177
Score = 32.3 bits (72), Expect = 1.4
Identities = 53/230 (23%), Positives = 97/230 (42%), Gaps = 23/230 (10%)
Query: 89 KTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLL 148
KT K L + IK+ E + A + + + +E +A L D NER+ EE SL
Sbjct: 1118 KTVKELQTQIKDLKEKLEAERTTRAK-MERERADLTQDLADLNERL-----EEVGGSSLA 1171
Query: 149 KKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIAD-LNELRYQ 207
+ E I KK E K KL +++ E LH+ + + K AD L EL Q
Sbjct: 1172 QLE-------ITKKQETKFQ------KLHRDMEEATLHFETTSASLKKRHADSLAELEGQ 1218
Query: 208 REDMSLAQSPGIWGEDPVKLTLALKMTR-QDLTRTQMELNNMKANFGDVVPRRDFEMQEK 266
E++ + + ++L + +TR + +TR + + + + + ++ +
Sbjct: 1219 VENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKV 1278
Query: 267 TN--KDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQ 314
T DL Q L + E + E L +E+ F ++++++
Sbjct: 1279 TQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLR 1328
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 47.4 bits (111), Expect = 4e-05
Identities = 136/644 (21%), Positives = 270/644 (41%), Gaps = 87/644 (13%)
Query: 20 NRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQPYRE 79
N+K S + + + +Q K Q +EE EN L+ E L + + R
Sbjct: 319 NKKLSSAENDRDILRREQEQLNVEKRQIMEECEN-LKLECSKLQPSAVKQSDTMTEKERI 377
Query: 80 IFEFF-IEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKL-VTVNEDCNERILAM 137
+ + +E+ + LS +N + + ++ A + LK K+ + V E E+ L
Sbjct: 378 LAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLE--KEKSLLS 435
Query: 138 RAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNL---AEEYLHYLSERDAC 194
+ +E+ ++SLLK N ++I ISL SE+ LR NL +E +SE++
Sbjct: 436 QEKEELQMSLLKLN--NEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKET- 492
Query: 195 KILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQME----LNNMKA 250
LIA++ EL Q ++ T + + + L++ Q E ++ +K
Sbjct: 493 --LIAEIEELDRQNQE----------------ATKHMILIKDQLSKQQNEGDSIISKLKQ 534
Query: 251 NFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSEL 310
+ D ++ E D+ ++LD + E++ + L LH++ K D+ + +
Sbjct: 535 DLND--EKKRVHQLEDDKMDITKELDVQK---EKLIQSEVALNDLHLTKQKLEDKVENLV 589
Query: 311 QEIQRTSTPRPDWTK----CKDVVAGGPER--------WQMLAEGKNSDQLVDVLLEEIG 358
++ ++ K K+ + E Q L + NS+ D LL+E
Sbjct: 590 DQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSN-FKDTLLKERE 648
Query: 359 SGLLREKDFFPGLGYGEAIPAFLRFDGLVENKK--PSKKDVVNLLKD--AWKERLAEEQK 414
+ + K L + FD +EN+K + +DV + L++ A +L+ E+
Sbjct: 649 AEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEK- 707
Query: 415 ETFPDFFFNFLEHRFGPSDA-MAWA--YTIFENIKIFHSNEVMSQF----YAVLMGKRSE 467
+ L+ G +A + WA + E K + E +S + L +
Sbjct: 708 ----NTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEH 763
Query: 468 NVYVTQKE--TVAQLLKEMTNADSQNEGLLTMEQFNTVLKSTFPLKTEEQIQELMEAGGW 525
+ + QK+ +A+L K + D+ + ++ VL S+ L+ ++Q+ +L+
Sbjct: 764 LIKLNQKKDMEIAELKKNIEQMDTDH------KETKDVLSSS--LEEQKQLTQLI----- 810
Query: 526 HPSSSNADLLNYRSLFMEDEEGQSEPFVQK--LWEQYMDEKDEYLQQLKQELGIELHEEV 583
+ + L RS +++E + ++K + Q ++EKD L +K+E H +
Sbjct: 811 NKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEE---NNHLQE 867
Query: 584 TLPKLRGGLMTIDPSLDKQTVNTYMSQAFQLPESEMPEEGDEKE 627
L +LR P D +T+++ A ++ + +E E+E
Sbjct: 868 ELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEE 911
Score = 43.9 bits (102), Expect = 5e-04
Identities = 51/243 (20%), Positives = 111/243 (45%), Gaps = 17/243 (6%)
Query: 81 FEFFIEDFKTYKPL-LSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNER--ILAM 137
+E IE+ + L S+++ +E ++ ++K + LK + ++ D E +L+
Sbjct: 739 YEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSS 798
Query: 138 RAEEKYEIS-LLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERD-ACK 195
EE+ +++ L+ K+++ + KL ++ ++ + L LRKN E + E+D +
Sbjct: 799 SLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKN--EILRQTIEEKDRSLG 856
Query: 196 ILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDV 255
+ + N L+ + E + QS DP L ++ + +LN +K + +
Sbjct: 857 SMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASE-----VSQLNTIKEHLEEE 911
Query: 256 VPRRD--FEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEI 313
+ E Q ++ L + L + +E R +HE + H E+D+ E++ +
Sbjct: 912 IKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDE---EIKSL 968
Query: 314 QRT 316
Q+T
Sbjct: 969 QKT 971
Score = 42.7 bits (99), Expect = 0.001
Identities = 103/456 (22%), Positives = 187/456 (41%), Gaps = 88/456 (19%)
Query: 114 RALEPLKAKLVTVNEDCNE-RILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSE 172
+ L+ K KL+ N+ + + E+K E NL+ ++K E +S+Q E
Sbjct: 555 KELDVQKEKLIQSEVALNDLHLTKQKLEDKVE---------NLVDQLNKSQESNVSIQKE 605
Query: 173 VTKLRKNLA--EEYLH---------------------YLSERDA-CKILIADLNELRYQR 208
+L++++ EE L L ER+A + L +L+EL
Sbjct: 606 NLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLN 665
Query: 209 EDM-SLAQSPGIWGEDPVKLTLALKMTRQDL-------TRTQMELN----NMKANFGDV- 255
E++ +A + E KL LA + R L + +E N +K G++
Sbjct: 666 ENLKKVAFDVKMENE---KLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIE 722
Query: 256 -----VPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSEL 310
+R E K K ++E + + ++ EHE L++L+ +++D +EL
Sbjct: 723 AELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLN----QKKDMEIAEL 778
Query: 311 QE-IQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGSGLLREKDFFP 369
++ I++ T D + KDV++ E + L + N ++ L+E S L E D
Sbjct: 779 KKNIEQMDT---DHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELD--- 832
Query: 370 GLGYGEAIPAFLRFDGLVENKK---PSKKDVVNLLKDAWKERLAEEQKETFPDFFFNFLE 426
Y +A+ +E K S K+ N L++ ERL EEQ T P L+
Sbjct: 833 --KYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEE-LERLREEQSRTAPVADPKTLD 889
Query: 427 HRFGPSDAMAWAYTIFENIKIFHSNEVMSQFYAVLMGKRSENVYVTQKETVAQLLKEMTN 486
+ ++ TI E+++ E+ K + + Q ++ QLL+ +
Sbjct: 890 SVTELASEVSQLNTIKEHLE----EEI----------KHHQKIIEDQNQSKMQLLQSLQE 935
Query: 487 ADSQ-NEGLLTMEQFNTVLKSTFPLKTEEQIQELME 521
+ +E EQ N F L+ +E+I+ L +
Sbjct: 936 QKKEMDEFRYQHEQMNATHTQLF-LEKDEEIKSLQK 970
Score = 30.8 bits (68), Expect = 4.1
Identities = 46/234 (19%), Positives = 99/234 (42%), Gaps = 17/234 (7%)
Query: 126 VNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKN-LAEEY 184
VN + E +L R + K ++ +++ K ++ + E LQ E+ +L+ L +
Sbjct: 1199 VNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSD 1258
Query: 185 LHYLSERDACKILIA-DLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQM 243
+ + D ++ + + NE + + LAQ G+ + T L + + D+ Q+
Sbjct: 1259 NNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQ--LCNTKDLLLGKLDIISPQL 1316
Query: 244 ELNNM---------KANFGDVVPRRDFEMQ---EKTNKDLQEQLDTLRASYEEVRKEHEI 291
++ +A+ +V+ +Q E+ K LQE+ T+R E + +
Sbjct: 1317 SSASLLTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDS 1376
Query: 292 LMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKN 345
+ KE +Q SE+++++ K KD++ Q+L+ +N
Sbjct: 1377 IAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSD-QLLSSNEN 1429
Score = 30.0 bits (66), Expect = 7.1
Identities = 60/279 (21%), Positives = 117/279 (41%), Gaps = 31/279 (11%)
Query: 95 LSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLK--KEK 152
L++IK E + H + K++ ++L E+K E+ + E+
Sbjct: 901 LNTIKEHLEEEIKHHQ-----------KIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQ 949
Query: 153 MNLL--KLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDAC--KILIADLN-ELRYQ 207
MN +L +K+EE SLQ + +++ L EE ++ + + LN E +
Sbjct: 950 MNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSE 1009
Query: 208 REDMSLAQSPG-IWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEK 266
+ D+S A++ + G +L + L + ++++ T+ K G + Q
Sbjct: 1010 KHDLSKAETERLVKGIKERELEIKL-LNEKNISLTKQIDQLSKDEVGKLT-------QII 1061
Query: 267 TNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQR-TSTPRPDWTK 325
KDL+ Q R S ++ L Q + ER++ F+ L E R S + ++ K
Sbjct: 1062 QQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHK 1121
Query: 326 CKDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGSGLLRE 364
D+VA + L + ++ ++ + E G + RE
Sbjct: 1122 MMDIVAA---KEAALIKLQDENKKLSTRFESSGQDMFRE 1157
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 47.4 bits (111), Expect = 4e-05
Identities = 62/304 (20%), Positives = 121/304 (39%), Gaps = 52/304 (17%)
Query: 52 ENYLRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQRE 111
++ L KE ++L L E L+ ++E + +++ K +K L + +
Sbjct: 1145 QDILEKESIILKL------ERNLKEFQEHLQDSVKNTKDLNVKELKLKEEIT-QLTNNLQ 1197
Query: 112 KIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQS 171
++ L LK + N E++ K E+S NL + +K E+ L+
Sbjct: 1198 DMKHLLQLKEEEEETNRQETEKL-------KEELSASSARTQNLKADLQRKEEDYADLKE 1250
Query: 172 EVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLAL 231
++T +K + + RD K+L +NEL ++ S L
Sbjct: 1251 KLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCS----------------QEL 1294
Query: 232 KMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEI 291
M ++ + + + +LNN K + E+ KDL + E++ ++ +
Sbjct: 1295 DMKQRTIQQLKEQLNNQKV-------EEAIQQYERACKDLNVK--------EKIIEDMRM 1339
Query: 292 LMQLHMSTLKERDQFF-SELQEIQRTSTPRPDW-TKCKDVVAGGPERWQMLAEGKNSDQL 349
++ T E+DQ ++L+E++R +T W KC D+ +R K +
Sbjct: 1340 TLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQR-----SNKEHENN 1394
Query: 350 VDVL 353
DVL
Sbjct: 1395 TDVL 1398
Score = 37.4 bits (85), Expect = 0.044
Identities = 49/236 (20%), Positives = 112/236 (47%), Gaps = 25/236 (10%)
Query: 106 LAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKK--N 163
L + E + ++ KL+ +ED ++ + +A +E K++ ++L++ + KK N
Sbjct: 535 LVEELENAEETQNVETKLL--DEDLDKTLEENKAFISHEE---KRKLLDLIEDLKKKLIN 589
Query: 164 EEKISLQSEVTKLRKNLAEEYLHYLSERDA-CKILIADLNELRYQREDMSLAQSPGIWG- 221
E+K L E K+R+ + +E+ Y ++R+A K + E+ + + LA + G
Sbjct: 590 EKKEKLTLEF-KIREEVTQEFTQYWAQREADFKETLLQEREILEENAERRLAIFKDLVGK 648
Query: 222 ----EDPVKLTLALKMTRQDLTR-TQMELNNMKANF----GDVVPRRDFEMQEKTNKDLQ 272
E+ K A K+ ++ T +++ N +KA G+++ ++ E++++ N+
Sbjct: 649 CDTREEAAKDICATKVETEEATACLELKFNQIKAELAKTKGELIKTKE-ELKKRENES-D 706
Query: 273 EQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKD 328
+ L S +++ +++ + +L + DQ + E Q + + KC D
Sbjct: 707 SLIQELETSNKKIITQNQRIKEL----INIIDQKEDTINEFQNLKSHMENTFKCND 758
Score = 33.9 bits (76), Expect = 0.49
Identities = 72/363 (19%), Positives = 146/363 (40%), Gaps = 38/363 (10%)
Query: 15 QTILQNRK-PCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLR-----------KELLLL 62
+TIL+ +K CS + ++ + L+E + +L+ KEL L
Sbjct: 1127 ETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLK 1186
Query: 63 DLGTDSTQELR-----LQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALE 117
+ T T L+ LQ E E ++ + K LS+ + + A + K
Sbjct: 1187 EEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYA 1246
Query: 118 PLKAKLVTVNEDCNE---RILAMRAEEKY---EISLLKKEKMNLLKLIDKKNEEKISLQS 171
LK KL + + + MR E+K +I+ L+K+K + +D K L+
Sbjct: 1247 DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKE 1306
Query: 172 EVTKLRKNLA-EEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWG--EDPVKLT 228
++ + A ++Y + + + +I D+ ++E + Q + E+ +L
Sbjct: 1307 QLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLA 1366
Query: 229 LALKMTRQ---DL-TRTQMELNNMKANFGDVVPRRDF------EMQEKTNKDLQEQLDTL 278
L+ ++ DL T+ N N DV+ + E ++K N D ++ L+
Sbjct: 1367 TELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEK 1426
Query: 279 RASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQ 338
+ ++ I + ++R++FF + E++ + + K D+ ER Q
Sbjct: 1427 MMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTE--KDSDLQKWREERDQ 1484
Query: 339 MLA 341
++A
Sbjct: 1485 LVA 1487
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 46.6 bits (109), Expect = 7e-05
Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 26/234 (11%)
Query: 103 EGMLAHQREKIRALEPLKAKLVT----VNEDCNERILAMRAEEKYEISLLK--KEKMNLL 156
E + E++ E + A+L + ++C+E R + E++L K KEK
Sbjct: 916 EAKVKEMNERLEDEEEMNAELTAKKRKLEDECSE---LKRDIDDLELTLAKVEKEKHATE 972
Query: 157 KLIDKKNEEKISLQ---SEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSL 213
+ EE L +++TK +K L E + L + A + + L + + + E
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 1032
Query: 214 AQSPGIWGEDPVKLTL--ALKMTRQDLTRTQ---MELNNMKANFGDVVPRRDFEM----- 263
+ E V++ L A + DL TQ M+L N K + + ++DFE+
Sbjct: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNA 1092
Query: 264 ----QEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEI 313
++ LQ++L L+A EE+ +E E K R EL+EI
Sbjct: 1093 RIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 1146
Score = 35.4 bits (80), Expect = 0.17
Identities = 40/157 (25%), Positives = 70/157 (44%), Gaps = 10/157 (6%)
Query: 140 EEKYEISLLKKEKMNL-LKLIDKKNEEKISLQSEVTKLR--KNLAEEYLHYLSERDACKI 196
E + E+ +KE +L +L KN + SL+ T R KNL EE + +
Sbjct: 1462 ESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGK 1521
Query: 197 LIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVV 256
I +L ++R Q E + + + +L+ + R Q+E N +KA +
Sbjct: 1522 TIHELEKVRKQLEAEKMELQSAL-----EEAEASLEHEEGKILRAQLEFNQIKAEIERKL 1576
Query: 257 PRRDFEMQEKTNKDLQEQLDTLRASYE-EVRKEHEIL 292
+D EM++ L+ +D+L+ S + E R +E L
Sbjct: 1577 AEKDEEMEQAKRNHLR-VVDSLQTSLDAETRSRNEAL 1612
Score = 30.0 bits (66), Expect = 7.1
Identities = 43/196 (21%), Positives = 80/196 (40%), Gaps = 18/196 (9%)
Query: 136 AMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACK 195
A+R + ++ L ++ NL ++ K +EK + E+ + N+ + + C+
Sbjct: 1191 ALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCR 1250
Query: 196 ILIADLNELRYQREDMS------LAQSPGIWGED-------PVKLTLALKMTRQDLTRTQ 242
L +NE R + E+ +Q + E+ K L ++TR LT TQ
Sbjct: 1251 TLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQ 1310
Query: 243 MELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKE 302
+L ++K + V ++ + + D LR YEE + L ++ E
Sbjct: 1311 -QLEDLKRQLEEEVKAKN--ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSE 1367
Query: 303 RDQFFS--ELQEIQRT 316
Q+ + E IQRT
Sbjct: 1368 VAQWRTKYETDAIQRT 1383
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 45.1 bits (105), Expect = 2e-04
Identities = 60/244 (24%), Positives = 101/244 (41%), Gaps = 26/244 (10%)
Query: 89 KTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLL 148
KT L + IK E A E+I A L AK + ++C+E + + E++L
Sbjct: 914 KTKIQLEAKIKEVTER--AEDEEEINA--ELTAKKRKLEDECSE---LKKDIDDLELTLA 966
Query: 149 K--KEKMNLLKLIDKKNEEKISLQSEVTKL---RKNLAEEYLHYLSERDACKILIADLNE 203
K KEK + EE L + KL +K L E + L + A + + L +
Sbjct: 967 KVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTK 1026
Query: 204 LRYQREDMSLAQSPGIWGEDPVKLTL--ALKMTRQDLTRTQ---MELNNMKANFGDVVPR 258
+ + E + E +++ L A + DL Q M++ N K + + +
Sbjct: 1027 AKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKK 1086
Query: 259 RDFEMQEKTNK---------DLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSE 309
++FEM +K LQ+++ L+A EE+ +E E K+R E
Sbjct: 1087 KEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1146
Query: 310 LQEI 313
L+EI
Sbjct: 1147 LEEI 1150
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 44.7 bits (104), Expect = 3e-04
Identities = 59/230 (25%), Positives = 102/230 (44%), Gaps = 32/230 (13%)
Query: 107 AHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLK--KEKMNLLKLIDKKNE 164
A E+I A L AK + ++C+E + + E++L K KEK + E
Sbjct: 927 AEDEEEINA--ELTAKKRKLEDECSE---LKKDIDDLELTLAKVEKEKHATENKVKNLTE 981
Query: 165 EKISLQSEVTKL---RKNLAEEYLHYLSERDACKILIADLNE----LRYQREDM--SLAQ 215
E L + KL +K L E + L + A + + LN+ L Q ED+ SL Q
Sbjct: 982 ELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 1041
Query: 216 SPGIWGE---DPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFE---MQEKTNK 269
+ + + KL LK+ ++ + ++L N K + + ++DFE +Q K
Sbjct: 1042 EKKLRVDLERNKRKLEGDLKLAQESI----LDLENDKQQLDERLKKKDFEYCQLQSKVED 1097
Query: 270 D------LQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEI 313
+ Q+++ L+A EE+ +E E T K+R + EL+E+
Sbjct: 1098 EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEEL 1147
Score = 37.0 bits (84), Expect = 0.058
Identities = 49/201 (24%), Positives = 88/201 (43%), Gaps = 19/201 (9%)
Query: 103 EGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKK 162
E L H+ KI ++ +L V + + +I AE+ EI LK+ ++ +
Sbjct: 1549 EAALEHEEAKILRIQ---LELTQVKSEIDRKI----AEKDEEIEQLKRNYQRTVETMQSA 1601
Query: 163 NEEKISLQSEVTKLRK------NLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQS 216
+ ++ ++E +L+K N E L + + R A + L L ++ Q +D L
Sbjct: 1602 LDAEVRSRNEAIRLKKKMEGDLNEIEIQLSH-ANRQAAETL-KHLRSVQGQLKDTQLHLD 1659
Query: 217 PGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQ-L 275
+ G++ +K LA+ R +L Q E+ ++A R QE + + + Q L
Sbjct: 1660 DALRGQEDLKEQLAIVERRANL--LQAEVEELRATLEQTERARKLAEQELLDSNERVQLL 1717
Query: 276 DTLRASYEEVRKEHEI-LMQL 295
T S +K+ E LMQL
Sbjct: 1718 HTQNTSLIHTKKKLETDLMQL 1738
Score = 31.6 bits (70), Expect = 2.4
Identities = 57/279 (20%), Positives = 107/279 (38%), Gaps = 42/279 (15%)
Query: 61 LLDLGTDSTQELRLQPYREIFEFF-----IEDFKTYKPLLSSIKNAYEGMLAHQREKIRA 115
+LDL D Q+L + ++ FE+ +ED +T + + E+I A
Sbjct: 1067 ILDLENDK-QQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEA 1125
Query: 116 LEPLKAKLVTVNEDCNERI--LAMRAEE-----KYEISLLKKEKMNLLKLIDKKNEEKIS 168
+AK D + L+ R EE +I L KK + LKL E +
Sbjct: 1126 ERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQ 1185
Query: 169 LQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLT 228
++ V LRK A D+ L ++ L+ ++ + +S
Sbjct: 1186 HEAMVAALRKKHA----------DSVAELGEQIDNLQRVKQKLEKEKS------------ 1223
Query: 229 LALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEK--TNKDLQEQLDTLRASYEEVR 286
K+ DL+ + ++ KAN + + ++ E N+++Q L L ++
Sbjct: 1224 -EFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQ 1282
Query: 287 KEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTK 325
E L + L+E++ S+L ++ T + + K
Sbjct: 1283 TEAGELSR----QLEEKESIVSQLSRSKQAFTQQTEELK 1317
>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
Length = 1113
Score = 44.3 bits (103), Expect = 4e-04
Identities = 56/257 (21%), Positives = 101/257 (39%), Gaps = 46/257 (17%)
Query: 68 STQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLV--- 124
S+ +L+ +E+ +E+ K L S + + +EK RA+E A++
Sbjct: 464 SSLTAQLESTKEMLRKVVEELTAKKMTLESSERTISDLTTSLQEKERAIEATNAEITKLR 523
Query: 125 ---------------------TVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKN 163
V +C L M ++K I +L+++ N+ +L+ +
Sbjct: 524 SRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMTEKDKV-IEILRQQIENMTQLVGQHG 582
Query: 164 E-------EKISLQSEVTKLRKNLAEEYLHYLSERDACKI--LIADLNELRYQREDMSLA 214
EK L+ E+ R L E L L ++ KI L A +++L ++ + A
Sbjct: 583 RTAGAMQVEKAQLEKEINDRRMELKE--LKILKDKKDAKIRELEARVSDLELEKVKLVNA 640
Query: 215 QSPGIWGEDPVK-----LTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNK 269
S + +K L +K +R +L E +K NF R E E T
Sbjct: 641 GSERLRAVKDIKQERDQLLNEVKTSRSELNNLSEEYEVLKRNF-----RNKSEEMEMTTN 695
Query: 270 DLQEQLDTLRASYEEVR 286
L+ QL + ++ E+ R
Sbjct: 696 KLKMQLKSAQSELEQTR 712
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 44.3 bits (103), Expect = 4e-04
Identities = 76/337 (22%), Positives = 133/337 (39%), Gaps = 58/337 (17%)
Query: 97 SIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLL 156
S+K A EG+ + + ++ +E LK+ + + + E+ ++ E YEI LL
Sbjct: 1571 SLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKE--YEI---------LL 1619
Query: 157 KLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQS 216
+ + + E +Q V +R+ E Y S K L E + E+M
Sbjct: 1620 QSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMK---- 1675
Query: 217 PGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLD 276
K+ K +Q + + E + ++A +V P D T K+ E L
Sbjct: 1676 --------EKMRKFAKSKQQKILELEEENDRLRA---EVHPAGD------TAKECMETLL 1718
Query: 277 TLRASYEE----VRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKDVVAG 332
+ AS +E V+ E+E L + S + E+D E+Q++ K + G
Sbjct: 1719 SSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDL-------------KHQIEG 1765
Query: 333 GPERWQMLAEGKNSDQLVDVLLEEIGS--GLLREKD---FFPGLGYGEAIPAFLRFDGLV 387
+ L + D +V E S G E+D E++P+ + V
Sbjct: 1766 NVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAV 1825
Query: 388 ENKKPSKKDVVNLLK--DAWKERLA--EEQKETFPDF 420
S ++ N L+ D KER+A EE+K+ +F
Sbjct: 1826 SKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEF 1862
Score = 42.4 bits (98), Expect = 0.001
Identities = 47/228 (20%), Positives = 102/228 (44%), Gaps = 15/228 (6%)
Query: 94 LLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILA-MRAEEKYEISLLKKEK 152
L+ ++ E E+I+ L+ ++ E+ E A + + K + +L+ +++
Sbjct: 1435 LIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKE 1494
Query: 153 MNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQRE--- 209
LK EE + + +L K+LA+ ++ ++ L L+ +R+
Sbjct: 1495 A--LKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLI 1552
Query: 210 ---DMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEK 266
D SL ++ + L LAL+ +D + E+ ++K++ E QEK
Sbjct: 1553 TEMDRSLLENQSL-SSSCESLKLALEGLTEDKEKLVKEIESLKSS----KIAESTEWQEK 1607
Query: 267 TNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQ 314
+K+LQ++ + L SYE V E E + + + +E+ + + +L+ +
Sbjct: 1608 -HKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTE 1654
Score = 42.4 bits (98), Expect = 0.001
Identities = 49/220 (22%), Positives = 89/220 (40%), Gaps = 24/220 (10%)
Query: 110 REKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEIS--------------LLKKEKMNL 155
+E++ + LK +D ER++ AE I LL+ E NL
Sbjct: 1902 QEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNL 1961
Query: 156 LKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYL---SERDACKILIADLNE-LRYQREDM 211
K + + EEK L E TK+ + +EYL + + K +L E L+ +++++
Sbjct: 1962 KKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEV 2021
Query: 212 SLAQSPGIWGEDPVK-LTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTN-- 268
Q I ++ + L +K T +Q +L K N V R E +
Sbjct: 2022 KQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFK 2081
Query: 269 ---KDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQ 305
D Q + + A +++KE + + S +K++D+
Sbjct: 2082 VLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDE 2121
Score = 40.4 bits (93), Expect = 0.005
Identities = 73/341 (21%), Positives = 147/341 (43%), Gaps = 53/341 (15%)
Query: 15 QTILQNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELLLLDLGTDSTQELRL 74
Q + Q +K C Y++++ + + RT K LE ++ +K+L + E R
Sbjct: 2019 QEVKQLQKDCIR-YQEKISALE----RTVKA--LEFVQTESQKDLEITKENLAQAVEHRK 2071
Query: 75 QPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRAL----EPLKAKLVTVNEDC 130
+ E+ F K LL ++ +LA + + L E +K+++ +ED
Sbjct: 2072 KAQAELASF--------KVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDL 2123
Query: 131 NERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQ--------------SEVTKL 176
R+ +AEEK+ KEK N+ + +D EK+ L+ EV +L
Sbjct: 2124 ERRL--EQAEEKH-----LKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL 2176
Query: 177 RKNLAEEYLHYLSERDACKILIADLNEL-----RYQREDMSLAQSPGIWGEDPVKLTL-A 230
++NL + + L D + + +++R+ QS E+ ++L
Sbjct: 2177 QENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSK----EEEIRLKEDN 2232
Query: 231 LKMTRQDLTRTQMELNNMKANFGDVV-PRRDFEMQEKTNKDLQEQL-DTLRASYEEVRKE 288
+ + L + + + +K N + ++ +E + +T LQ+++ DTL+ +E+ +
Sbjct: 2233 CSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQ 2292
Query: 289 HEILMQLHMSTLKERDQFFSELQEIQRTSTPRPD-WTKCKD 328
E L+ S+ E + SEL+ ++ T + KCK+
Sbjct: 2293 LEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKE 2333
Score = 32.3 bits (72), Expect = 1.4
Identities = 64/295 (21%), Positives = 124/295 (42%), Gaps = 41/295 (13%)
Query: 46 QYLEELENYLRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGM 105
Q + EL++ +R++ + L ++ QE R +I + + K L+S+ E M
Sbjct: 59 QLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHA----KAKLTSLNKYIEEM 114
Query: 106 LAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEE 165
A Q + EP + ++ ++ + EE+ EI +K + +LI +
Sbjct: 115 KA-QGGTVLPTEPQSEEQLSKHDKSS-------TEEEMEIEKIKHKLQEKEELISTLQAQ 166
Query: 166 KISLQSEVTKLRKNLAEEYL---HYLSERDA-CKILIADLNELRYQREDMSLAQSPGIWG 221
Q+E EE++ L E++ L A L++ + ++ + +
Sbjct: 167 LTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARF 226
Query: 222 EDPVKL---TLALKMTRQDL-TRTQMELNNM-------------KANFGDVVPRRDFEMQ 264
E V+L L +T+ D+ T Q +L + +A D++ +++
Sbjct: 227 ETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLL-QQELTAA 285
Query: 265 EKTNKDLQEQL-------DTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQE 312
E+ N+ L +QL +TLR + E R+E +IL++ + ER F LQE
Sbjct: 286 EQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQE 340
Score = 31.6 bits (70), Expect = 2.4
Identities = 59/296 (19%), Positives = 116/296 (39%), Gaps = 47/296 (15%)
Query: 71 ELRLQPYREIFEFFIEDFKTYKP----LLSSIKNAYEGMLAHQREK----IRALEPLKAK 122
E LQ RE+ E+ + LLS + A + +A R++ I+ LE L ++
Sbjct: 2360 ETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQ 2419
Query: 123 LVTVN---EDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKL--- 176
N E+ N++ + + + +KKE + +D + SLQ++ ++
Sbjct: 2420 EEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGD 2479
Query: 177 RKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQ 236
+ L E +L + E+D I A + + E L + KL L R+
Sbjct: 2480 YQQLEERHLSIILEKDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYRE 2538
Query: 237 DLTRT------------------QMELNNMKANFGDVVP---------RRDFEMQEKTNK 269
DL + EL N A + + RR F ++ +
Sbjct: 2539 DLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQ 2598
Query: 270 DLQEQLDTLRASYEEVRKEHEILMQ-----LHMSTLKERDQFFSELQEIQRTSTPR 320
DL +++++L+ S ++ ++ L + L+ + LK +++ L + +S R
Sbjct: 2599 DLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKR 2654
Score = 29.6 bits (65), Expect = 9.2
Identities = 32/132 (24%), Positives = 55/132 (41%), Gaps = 27/132 (20%)
Query: 143 YEISLLKKEKMNLLKLIDKKN--------------EEKISLQSEVTKLRKNLAEEYLHYL 188
YE LL+ + + LK I +K EEK +L ++ ++L E HY
Sbjct: 3025 YETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYG 3084
Query: 189 SERDACKILIADLNELRYQREDMSLAQSPGIWGE--------DPVKL---TLALKMTRQD 237
+ C +L + EL Q +++ +PG E DP +L + +Q
Sbjct: 3085 DLLNHCAVLEKQVQEL--QAGPLNIDVAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQQ 3142
Query: 238 LTRTQMELNNMK 249
L T+ E+N ++
Sbjct: 3143 LCNTRQEVNELR 3154
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 43.9 bits (102), Expect = 5e-04
Identities = 51/206 (24%), Positives = 91/206 (44%), Gaps = 24/206 (11%)
Query: 91 YKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKK 150
YK IK +L H + I++ L+ KLV E+ AEEK K
Sbjct: 311 YKHCQQKIKELELEVLKHT-QSIKSQNNLQEKLV------QEKSKVADAEEKILDLQRKL 363
Query: 151 EKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQRED 210
E + + L D EK L+ ++ + +N A+ Y E+ K+L +++EL Q
Sbjct: 364 EHAHKVCLTDTCISEKQQLEEKIKEATQNEAKVKQQYQEEQQKRKLLYQNVDELHRQVRT 423
Query: 211 MSLAQSPGIWGEDPVKLTLALKMTR-QDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNK 269
+ E+ +++T + + +R Q +L N K R ++ K+N+
Sbjct: 424 LQDK-------ENLLEMTCSQQQSRIQQQEALLKQLENEK---------RKYDEHVKSNQ 467
Query: 270 DLQEQLDTLRASYEEVRKEHEILMQL 295
+L E+L L+ E +R+E+ L++L
Sbjct: 468 ELSEKLSKLQQEKEALREEYLRLLKL 493
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 43.9 bits (102), Expect = 5e-04
Identities = 63/266 (23%), Positives = 113/266 (42%), Gaps = 51/266 (19%)
Query: 95 LSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCN---------ERILAMRAEEKYEI 145
LS+++ E A +EKI+ L+ + +L+T+ +D N E++ ++ +
Sbjct: 1804 LSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTL 1863
Query: 146 SLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIAD--LNE 203
S L+ E +NL + + + EE S+ E LR+ EE L ERD K + + +
Sbjct: 1864 SKLEIENLNLAQKLHENLEEMKSVMKERDNLRR--VEETLKL--ERDQLKESLQETKARD 1919
Query: 204 LRYQREDMSLAQSPGIWGEDPVKL-------TLALKMTRQDLTRTQMELNN-----MKAN 251
L Q+E + E KL T+ + ++DL +++ EL K
Sbjct: 1920 LEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKE 1979
Query: 252 FGDVVPRRDFEMQEKTNKDLQE---------------QLDT------LRASYEEVR---K 287
+ + D M K ++++ ++D L S EE+R K
Sbjct: 1980 LQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAK 2039
Query: 288 EHEILMQLHMSTLKERDQFFSELQEI 313
E + L ++ S ERDQF + L+E+
Sbjct: 2040 ERDELRRIKESLKMERDQFIATLREM 2065
Score = 42.0 bits (97), Expect = 0.002
Identities = 49/193 (25%), Positives = 90/193 (46%), Gaps = 29/193 (15%)
Query: 150 KEKMNLLKLIDKKNEEKISLQS---EVTKLRKNLAEEYLHYLSERDACKILIADLNELRY 206
+++ + LI +KNE + L+S E +L+ +L E + ++ ++L +EL+
Sbjct: 1040 EQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLG---DELKK 1096
Query: 207 QREDMSLAQSPGIWGEDPVKLTL--------ALKMTRQDLTRTQMELNNMKANFGDVVPR 258
Q+E ++ ++ I E + T LK Q L Q +L N++ ++ +
Sbjct: 1097 QQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKK 1156
Query: 259 -RDFE--MQEKTNKDLQ-EQLDT--------LRASYEEVR---KEHEILMQLHMSTLKER 303
+ E E NK+L E ++T L +YEEV+ KE ++L +L S ER
Sbjct: 1157 INEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETER 1216
Query: 304 DQFFSELQEIQRT 316
D ++EI+ T
Sbjct: 1217 DHLRGYIREIEAT 1229
Score = 36.2 bits (82), Expect = 0.099
Identities = 74/341 (21%), Positives = 142/341 (41%), Gaps = 53/341 (15%)
Query: 55 LRKELLLLDLGTDSTQELRLQPYR-EIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKI 113
LR+E++LL EL+ P E I+D +++S K+ + H+ ++
Sbjct: 739 LREEVILLS-------ELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRV 791
Query: 114 RAL----EPLKAKLVTVNEDC--------NERILAMRAEEKYEISLLKKEKM-----NLL 156
+ L K L T + N + L M E+KY++ L + E+M NL
Sbjct: 792 QGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLS 851
Query: 157 KLIDKKNEEKISLQSEVTKLRKNLAE---EYLHYLSERDACKILI--ADLNELRYQREDM 211
K K + +L++E++ + L E E L+E + K + D +RE
Sbjct: 852 KEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKT 911
Query: 212 SLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTN--- 268
+ + E+ LT +Q Q+E + +K++ D V + + QE+
Sbjct: 912 LITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTV-NMNIDTQEQLRNAL 970
Query: 269 ---KDLQEQLDTLRASYEEVRKEHEILMQLHM--STLKERDQFFSEL--------QEIQR 315
K QE ++TL++ E E+ LHM +T + +D+F ++ E +
Sbjct: 971 ESLKQHQETINTLKSKISE-----EVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKN 1025
Query: 316 TSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEE 356
T T D K +++ + + ++ E Q+++ ++ E
Sbjct: 1026 TQTLTAD-VKDNEIIEQQRKIFSLIQEKNELQQMLESVIAE 1065
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 43.9 bits (102), Expect = 5e-04
Identities = 59/244 (24%), Positives = 101/244 (41%), Gaps = 26/244 (10%)
Query: 89 KTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLL 148
KT L + IK E A E+I A L AK + ++C+E + + E++L
Sbjct: 916 KTKIQLEAKIKEVTER--AEDEEEINA--ELTAKKRKLEDECSE---LKKDIDDLELTLA 968
Query: 149 K--KEKMNLLKLIDKKNEEKISLQSEVTKL---RKNLAEEYLHYLSERDACKILIADLNE 203
K KEK + EE L + KL +K L E + L + A + + L +
Sbjct: 969 KVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTK 1028
Query: 204 LRYQREDMSLAQSPGIWGEDPVKLTL--ALKMTRQDLTRTQ---MELNNMKANFGDVVPR 258
+ + E + E +++ L A + DL Q M++ N K + + +
Sbjct: 1029 AKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKK 1088
Query: 259 RDFEMQEKTNK---------DLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSE 309
++FE+ +K LQ+++ L+A EE+ +E E K+R E
Sbjct: 1089 KEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148
Query: 310 LQEI 313
L+EI
Sbjct: 1149 LEEI 1152
Score = 35.4 bits (80), Expect = 0.17
Identities = 62/309 (20%), Positives = 123/309 (39%), Gaps = 41/309 (13%)
Query: 41 RTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQPYR-EIFEFFIEDFKTYKPLLSSIK 99
+ A + L++LE R+ L +D T+++ R E + + K L +
Sbjct: 1491 KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAAL 1550
Query: 100 NAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLI 159
E L H+ KI ++ +L V + + +I AE+ EI LK+ + +++ +
Sbjct: 1551 EEAEASLEHEEGKILRIQ---LELNQVKSEVDRKI----AEKDEEIDQLKRNHIRIVESM 1603
Query: 160 DKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGI 219
+ +I +++ +L+K + DLNE+ Q + + +
Sbjct: 1604 QSTLDAEIRSRNDAIRLKKKME-----------------GDLNEMEIQLNHANRMAAEAL 1646
Query: 220 WGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLR 279
+ T+ L TQ+ L++ + D+ + M E+ LQ +++ LR
Sbjct: 1647 RN---------YRNTQGILKDTQIHLDDALRSQEDL--KEQLAMVERRANLLQAEIEELR 1695
Query: 280 ASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQM 339
A+ E+ + +I Q + ER Q L Q TS D+ E +
Sbjct: 1696 ATLEQTERSRKIAEQ-ELLDASERVQ----LLHTQNTSLINTKKKLETDISQMQGEMEDI 1750
Query: 340 LAEGKNSDQ 348
L E +N+++
Sbjct: 1751 LQEARNAEE 1759
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 43.9 bits (102), Expect = 5e-04
Identities = 59/244 (24%), Positives = 101/244 (41%), Gaps = 26/244 (10%)
Query: 89 KTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLL 148
KT L + IK E A E+I A L AK + ++C+E + + E++L
Sbjct: 916 KTKIQLEAKIKEVTER--AEDEEEINA--ELTAKKRKLEDECSE---LKKDIDDLELTLA 968
Query: 149 K--KEKMNLLKLIDKKNEEKISLQSEVTKL---RKNLAEEYLHYLSERDACKILIADLNE 203
K KEK + EE L + KL +K L E + L + A + + L +
Sbjct: 969 KVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTK 1028
Query: 204 LRYQREDMSLAQSPGIWGEDPVKLTL--ALKMTRQDLTRTQ---MELNNMKANFGDVVPR 258
+ + E + E +++ L A + DL Q M++ N K + + +
Sbjct: 1029 AKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKK 1088
Query: 259 RDFEMQEKTNK---------DLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSE 309
++FE+ +K LQ+++ L+A EE+ +E E K+R E
Sbjct: 1089 KEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148
Query: 310 LQEI 313
L+EI
Sbjct: 1149 LEEI 1152
Score = 35.4 bits (80), Expect = 0.17
Identities = 62/309 (20%), Positives = 123/309 (39%), Gaps = 41/309 (13%)
Query: 41 RTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQPYR-EIFEFFIEDFKTYKPLLSSIK 99
+ A + L++LE R+ L +D T+++ R E + + K L +
Sbjct: 1491 KNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAAL 1550
Query: 100 NAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLI 159
E L H+ KI ++ +L V + + +I AE+ EI LK+ + +++ +
Sbjct: 1551 EEAEASLEHEEGKILRIQ---LELNQVKSEVDRKI----AEKDEEIDQLKRNHIRIVESM 1603
Query: 160 DKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGI 219
+ +I +++ +L+K + DLNE+ Q + + +
Sbjct: 1604 QSTLDAEIRSRNDAIRLKKKME-----------------GDLNEMEIQLNHANRMAAEAL 1646
Query: 220 WGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLR 279
+ T+ L TQ+ L++ + D+ + M E+ LQ +++ LR
Sbjct: 1647 RN---------YRNTQGILKDTQIHLDDALRSQEDL--KEQLAMVERRANLLQAEIEELR 1695
Query: 280 ASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQM 339
A+ E+ + +I Q + ER Q L Q TS D+ E +
Sbjct: 1696 ATLEQTERSRKIAEQ-ELLDASERVQ----LLHTQNTSLINTKKKLETDISQMQGEMEDI 1750
Query: 340 LAEGKNSDQ 348
L E +N+++
Sbjct: 1751 LQEARNAEE 1759
>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
Length = 1080
Score = 43.9 bits (102), Expect = 5e-04
Identities = 63/235 (26%), Positives = 101/235 (42%), Gaps = 44/235 (18%)
Query: 117 EPLKAKLVTVNEDCNERILAMRAEEKYEISLLKK-----EKMNLLKLIDKKNEE-----K 166
E + A+L ++ C ER+ +A+ + EI LK+ EK K I +K ++
Sbjct: 646 EAVVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKWISEKTKKIKEVTV 705
Query: 167 ISLQSEVTKL----------RKNLAEEYLHYLSERDACKILIADLNELRYQ--REDMSLA 214
L+ E+ KL K+L E L ER A + + ELR Q RE +L
Sbjct: 706 RGLEPEIQKLIARHKQEVRRLKSLHEAELLQSDER-ASQRCLRQAEELREQLEREKEALG 764
Query: 215 QSPGIWGEDPVKLTL-----ALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNK 269
Q + L AL+ RQ R E+ + G R+ E++E
Sbjct: 765 QQERERARQRFQQHLEQEQWALQQQRQ---RLYSEVAEERERLGQQAARQRAELEE---- 817
Query: 270 DLQEQLD--------TLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRT 316
L++QL+ LRA +E+ R+E E Q+ ++TLK++ + + E RT
Sbjct: 818 -LRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQQLELERQAWEAGRT 871
>gi|38045919 huntingtin interacting protein 1 [Homo sapiens]
Length = 1037
Score = 43.5 bits (101), Expect = 6e-04
Identities = 49/201 (24%), Positives = 88/201 (43%), Gaps = 27/201 (13%)
Query: 126 VNEDCNERILAMRAEEKY-EISLLKKEKMNLLKLIDKKNEEKISLQ--SEVTKLRKNLAE 182
VN+D + ++ E Y EIS LK + N+ K +++ LQ V++L +LAE
Sbjct: 368 VNKDEKDHLI----ERLYREISGLKAQLENM-----KTESQRVVLQLKGHVSELEADLAE 418
Query: 183 EYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQ 242
+ D C+ L A+L+ELR QRED AQ ++ + Q ++ +
Sbjct: 419 QQHLRQQAADDCEFLRAELDELRRQREDTEKAQ------RSLSEIERKAQANEQRYSKLK 472
Query: 243 MELNNMKANFGDVVPR-----RDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHM 297
+ + + N D++ + + M + DL+ + L S E + + + Q +
Sbjct: 473 EKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQL 532
Query: 298 STLKERDQFFS----ELQEIQ 314
L+ Q + ELQ +Q
Sbjct: 533 EVLESLKQELATSQRELQVLQ 553
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 43.1 bits (100), Expect = 8e-04
Identities = 125/655 (19%), Positives = 249/655 (38%), Gaps = 85/655 (12%)
Query: 48 LEELENYLRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSI---KNAYEG 104
LE+ +L + + L + + E R++ + + E K LS I K +
Sbjct: 556 LEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKK 615
Query: 105 MLAHQREKIRALEPLKAKLVTVNED--------CNERILAMRAEE-KYEISLLKKEKMNL 155
L H +EK E L+ +L + ++ N +I + E + E S L++E L
Sbjct: 616 ELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKL 675
Query: 156 LKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQ 215
K +D L+S + K L EE L ++ K + +L+ + +++ +
Sbjct: 676 KKTLDSFKNLTFQLES-LEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734
Query: 216 SPGIWGEDPVKL----TLALKMTRQDLTRTQMELNNMKANFGDVVPR-----RDFEMQEK 266
G + +K T L+++ Q L L N + + +D EM+ +
Sbjct: 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Query: 267 TNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKC 326
T + E+L E++ KE++ L Q K++ Q E + +++ + + +
Sbjct: 795 TLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Query: 327 KDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGSGLLREKDFFPGLGYGEAIPAFLRFDGL 386
+V G E+ E K + + + E EK+ L
Sbjct: 855 NNVKIGNLEK-----ENKTLSKEIGIYKESCVRLKELEKE----------------NKEL 893
Query: 387 VENKKPSKKDVVNLLKDAWKERLAEEQKETFPDFFFNFLEHRFGPSDAMAWAYTIFENIK 446
V+ K +V L +D E+L +Q + + LE + G +
Sbjct: 894 VKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELE-KIG-----------LNKER 941
Query: 447 IFHSNEVMSQFYAVLMGKRSENVYVT---QKETVAQLLKEMTNADSQNEGLLTMEQFNTV 503
+ H + Y +L K + + ++E +A L + + + N+ L ++ TV
Sbjct: 942 LLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQL--RQELKTV 999
Query: 504 LKSTFPLKTEEQIQELM--------EAGGWHPSS--SNADLLNYRSLFMEDEEG----QS 549
K+ LK + + ++ E W S + +LL + +E E Q+
Sbjct: 1000 KKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQA 1059
Query: 550 EPFVQKLWEQYMDEKDEYLQQ---LKQELGIELHEEVTLPKLRGGLMTIDPSLDKQTVNT 606
E K + ++ ++ LQ Q + L E+ T + + + ++ S +
Sbjct: 1060 EKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTS 1119
Query: 607 YMSQAFQL--PESEMPEEGDE--KEEAVVEILQTAL----ERLQVIDIRRVGPRE 653
M+Q QL +S + E + KE ++ L +L E+L+++ R+ E
Sbjct: 1120 LMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYE 1174
Score = 36.6 bits (83), Expect = 0.075
Identities = 42/232 (18%), Positives = 96/232 (41%), Gaps = 18/232 (7%)
Query: 91 YKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKK 150
YK L S +++ + L + EKI ALE + N+ + + ++ + YE ++
Sbjct: 953 YKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVK--KNYEALKQRQ 1010
Query: 151 EKMNLLKLI-------DKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNE 203
++ +++ +K E E+ K++ L E + + + + L L +
Sbjct: 1011 DEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQ 1070
Query: 204 LRYQREDMSL------AQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVP 257
L Q ++ Q+ + ++ T K+ ++ T + M N ++
Sbjct: 1071 LETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1130
Query: 258 RRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSE 309
+ E + N+ + ++ + L++ Y+ + K+HE L LH E + S+
Sbjct: 1131 QSSLENE---NESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISK 1179
Score = 34.3 bits (77), Expect = 0.37
Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 19/142 (13%)
Query: 170 QSEVTKLRKNLAEEYLHYLSERDACKILIADLNE----LRYQREDMSLAQSPGIWGEDPV 225
Q ++ L KN+A + ERD I +L+E L + S AQSP G +
Sbjct: 183 QEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSP--CGSPGM 240
Query: 226 KLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNK--DLQEQLDTLRASYE 283
K T +RQ L+ +EL + KA + R E++EKT + D +++L+ + +
Sbjct: 241 KRT----ESRQHLS---VELADAKAK----IRRLRQELEEKTEQLLDCKQELEQMEIELK 289
Query: 284 EVRKEHEILMQLHMSTLKERDQ 305
+++E+ L+ S RD+
Sbjct: 290 RLQQENMNLLSDARSARMYRDE 311
Score = 34.3 bits (77), Expect = 0.37
Identities = 53/215 (24%), Positives = 88/215 (40%), Gaps = 30/215 (13%)
Query: 106 LAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLL---KLIDKK 162
LA + KIR L + DC + + M + E+ L++E MNLL +
Sbjct: 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQM----EIELKRLQQENMNLLSDARSARMY 308
Query: 163 NEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGE 222
+E +L+ + ++ K L E Y + A + EL+ ED + E
Sbjct: 309 RDELDALREKAVRVDK-LESEVSRYKERLHDIEFYKARVEELK---EDNQVLLETKTMLE 364
Query: 223 DPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASY 282
D ++ T A +L + ++L KA D+ RD M K ++L E+ TL +
Sbjct: 365 DQLEGTRARSDKLHELEKENLQL---KAKLHDMEMERD--MDRKKIEELMEENMTLEMAQ 419
Query: 283 EEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTS 317
++ E LH+ EL++I RTS
Sbjct: 420 KQSMDE-----SLHLGW---------ELEQISRTS 440
Score = 30.4 bits (67), Expect = 5.4
Identities = 54/261 (20%), Positives = 102/261 (39%), Gaps = 35/261 (13%)
Query: 48 LEELENY---LRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEG 104
LEE NY LR+EL + ++ ++ R+ E ++ P +S N +E
Sbjct: 982 LEESTNYNQQLRQELKTVKKNYEALKQ------RQDEERMVQS----SPPISGEDNKWE- 1030
Query: 105 MLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNE 164
+E R L +K +L+ V + N + A + K ++ L+ + NL I
Sbjct: 1031 --RESQETTRELLKVKDRLIEVERN-NATLQAEKQALKTQLKQLETQNNNLQAQILALQR 1087
Query: 165 EKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDP 224
+ +SLQ + T L+ A+ + + L+ +L Q+ + E
Sbjct: 1088 QTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENEN------ESV 1141
Query: 225 VKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEE 284
+K LK L + +L + E Q + L + TL+++++
Sbjct: 1142 IKEREDLKSLYDSLIKDHEKLELLH------------ERQASEYESLISKHGTLKSAHKN 1189
Query: 285 VRKEHEILMQLHMSTLKERDQ 305
+ EH L + LK++ Q
Sbjct: 1190 LEVEHRDLEDRYNQLLKQKGQ 1210
>gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]
Length = 757
Score = 43.1 bits (100), Expect = 8e-04
Identities = 55/249 (22%), Positives = 109/249 (43%), Gaps = 31/249 (12%)
Query: 94 LLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKM 153
++ ++K Y + EK+ K +L+T+ D N+ + KY+ L+K+E
Sbjct: 73 MIDNLKVDYLTKIEELEEKLNDALHQK-QLLTLRLD-NQLAFQQKDASKYQ-ELMKQEME 129
Query: 154 NLLKLIDKKNEEKISLQSEVTKLRKNLA------EEYL-------------HYLSER--D 192
+L + E + L+ + +R+NL E+Y+ Y+S R +
Sbjct: 130 TILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQYIKLKAFPEDQLSIPEYVSVRFYE 189
Query: 193 ACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANF 252
L ++ EL+ ++ LA+ +LT + R++ + Q+ +
Sbjct: 190 LVNPLRKEICELQVKKN--ILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLALEL 247
Query: 253 GD---VVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSE 309
D ++ + D+ QE +K ++ + D L E+R++HEIL HM KER + E
Sbjct: 248 ADTKQLIQQGDYR-QENYDK-VKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKE 305
Query: 310 LQEIQRTST 318
+ +++T T
Sbjct: 306 VVTLEQTVT 314
Score = 39.7 bits (91), Expect = 0.009
Identities = 78/323 (24%), Positives = 139/323 (43%), Gaps = 52/323 (16%)
Query: 45 PQYLE----ELENYLRKELLLLDLGTD------STQELRLQPYREIFEFFIEDFKTYKPL 94
P+Y+ EL N LRKE+ L + + ST + +L+ E +E ED K Y +
Sbjct: 180 PEYVSVRFYELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETYE---EDRKNYSEV 236
Query: 95 -LSSIKNAYEGMLAHQREKIRALEPLKA---KLVTVNEDCNERILAMRAEEKYEISLLKK 150
+ + A E LA ++ I+ + + K+ + + + ++ +R K+EI L+
Sbjct: 237 QIRCQRLALE--LADTKQLIQQGDYRQENYDKVKSERDALEQEVIELR--RKHEI--LEA 290
Query: 151 EKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLS---------ERDACKILIADL 201
M K + ++E ++L+ VT L+K+ +EYL+ + E D + L A L
Sbjct: 291 SHMIQTKERSELSKEVVTLEQTVTLLQKD--KEYLNRQNMELSVRCAHEEDRLERLQAQL 348
Query: 202 NELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFG-DVVPRRD 260
E + RE+M E V K ++ ++E +K N D +
Sbjct: 349 EESKKAREEMY---------EKYVASRDHYKTEYENKLHDELEQIRLKTNQEIDQLRNAS 399
Query: 261 FEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQ-RTSTP 319
EM E+ N++L+E D A E E + L++ DQ +E+Q T +
Sbjct: 400 REMYERENRNLREARDNAVA-------EKERAVMAEKDALEKHDQLLDRYRELQLSTESK 452
Query: 320 RPDWTKCKDVVAGGPERWQMLAE 342
++ + + ER Q+L E
Sbjct: 453 VTEFLHQSKLKSFESERVQLLQE 475
Score = 33.9 bits (76), Expect = 0.49
Identities = 42/223 (18%), Positives = 94/223 (42%), Gaps = 24/223 (10%)
Query: 107 AHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKL-----IDK 161
AH+ +++ L+ + E+ E+ +A R K E +++ ++L ID+
Sbjct: 335 AHEEDRLERLQAQLEESKKAREEMYEKYVASRDHYKTEYENKLHDELEQIRLKTNQEIDQ 394
Query: 162 -KNEEKISLQSEVTKLRKN----LAEEYLHYLSERDACKI---LIADLNELRYQREDM-- 211
+N + + E LR+ +AE+ ++E+DA + L+ EL+ E
Sbjct: 395 LRNASREMYERENRNLREARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQLSTESKVT 454
Query: 212 SLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDL 271
+ + ++ L + T ++LT+ Q+E + +V+ + + +Q + K +
Sbjct: 455 EFLHQSKLKSFESERVQLLQEETARNLTQCQLECEKYQKKL-EVLTKEFYSLQASSEKRI 513
Query: 272 QEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQ 314
E + EH+ + ++ KE D+ + EI+
Sbjct: 514 TE--------LQAQNSEHQARLDIYEKLEKELDEIIMQTAEIE 548
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 42.7 bits (99), Expect = 0.001
Identities = 45/226 (19%), Positives = 100/226 (44%), Gaps = 23/226 (10%)
Query: 99 KNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKL 158
KNA + + +E + +E K ++ ++ EK + L +KEK L K
Sbjct: 280 KNAVQQL---HKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDL-RKEKETLEKK 335
Query: 159 IDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPG 218
+ N+E +++ +L + + Y ++ LI ++++L +ED++
Sbjct: 336 LRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKL---KEDINSHVIKV 392
Query: 219 IWGEDPVKLTL--------ALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKD 270
W ++ +K + LK T LT+ + E + ++ N D++ E +E + +
Sbjct: 393 KWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQ-ESEEIKSNE 451
Query: 271 LQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRT 316
L +L + E+ +E +++H + +K EL++++RT
Sbjct: 452 LDAKLRVTKGELEKQMQEKSDQLEMHHAKIK-------ELEDLKRT 490
Score = 36.6 bits (83), Expect = 0.075
Identities = 54/236 (22%), Positives = 101/236 (42%), Gaps = 38/236 (16%)
Query: 144 EISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNE 203
+I L +EK L +L + K E L E+ KL++++ H + + A L A+++
Sbjct: 349 KIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINS---HVIKVKWAQNKLKAEMDS 405
Query: 204 LRYQREDMSLAQSPGIWGEDPVKLTLA------LKMTRQDLTRTQMELNNMKANFGDVVP 257
+ ++ + E KLT A ++ QD+ +T E +K+N D
Sbjct: 406 HKETKDKLK---------ETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKL 456
Query: 258 R-----RDFEMQEKTN---------KDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKER 303
R + +MQEK++ K+L++ T + +E+R + L L+
Sbjct: 457 RVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTE 516
Query: 304 DQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGS 359
D+ S+ +EI + + + D V + + L GK Q ++ L EE+ S
Sbjct: 517 DE-LSKYKEI--INRQKAEIQNLLDKVKTADQLQEQLQRGK---QEIENLKEEVES 566
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 42.4 bits (98), Expect = 0.001
Identities = 75/353 (21%), Positives = 137/353 (38%), Gaps = 49/353 (13%)
Query: 19 QNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQPYR 78
QN D +++ + +HP A+P +L + LR+ T ST + YR
Sbjct: 647 QNYTEWLQDLKEKGPTLLKHPPAPAEPS--SDLASKLREAE-----ETQSTLQAECDQYR 699
Query: 79 EIF---EFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRA--------LEPLKAKLVTVN 127
I E + D + + A G + +K R +E LK +L + +
Sbjct: 700 SILAETEGMLRDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELES-S 758
Query: 128 EDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHY 187
+ E + AE + ++ E N K + + + QS++ + ++
Sbjct: 759 DQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQ---- 814
Query: 188 LSERDACKILIADLNELRYQREDMSLAQSPGIWGE------DPVKLTLALKMTRQDLTRT 241
D ++ L+E++ ED +A +P E DPV+L L+ T L
Sbjct: 815 ---SDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAILEDE 871
Query: 242 QMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLK 301
Q + + A +FE + + LQE+L+ LR + E E QL K
Sbjct: 872 QTQRQKLTA---------EFEEAQTSACRLQEELEKLRTAGPLESSETEEASQLKERLEK 922
Query: 302 ER------DQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQ 348
E+ + + LQE+ +T+ + + KD V E+ + +G +S +
Sbjct: 923 EKKLTSDLGRAATRLQELLKTT--QEQLAREKDTVKKLQEQLEKAEDGSSSKE 973
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 42.4 bits (98), Expect = 0.001
Identities = 75/353 (21%), Positives = 137/353 (38%), Gaps = 49/353 (13%)
Query: 19 QNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQPYR 78
QN D +++ + +HP A+P +L + LR+ T ST + YR
Sbjct: 647 QNYTEWLQDLKEKGPTLLKHPPAPAEPS--SDLASKLREAE-----ETQSTLQAECDQYR 699
Query: 79 EIF---EFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRA--------LEPLKAKLVTVN 127
I E + D + + A G + +K R +E LK +L + +
Sbjct: 700 SILAETEGMLRDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELES-S 758
Query: 128 EDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHY 187
+ E + AE + ++ E N K + + + QS++ + ++
Sbjct: 759 DQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQ---- 814
Query: 188 LSERDACKILIADLNELRYQREDMSLAQSPGIWGE------DPVKLTLALKMTRQDLTRT 241
D ++ L+E++ ED +A +P E DPV+L L+ T L
Sbjct: 815 ---SDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAILEDE 871
Query: 242 QMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLK 301
Q + + A +FE + + LQE+L+ LR + E E QL K
Sbjct: 872 QTQRQKLTA---------EFEEAQTSACRLQEELEKLRTAGPLESSETEEASQLKERLEK 922
Query: 302 ER------DQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQ 348
E+ + + LQE+ +T+ + + KD V E+ + +G +S +
Sbjct: 923 EKKLTSDLGRAATRLQELLKTT--QEQLAREKDTVKKLQEQLEKAEDGSSSKE 973
>gi|112734867 retinitis pigmentosa GTPase regulator interacting
protein 1 [Homo sapiens]
Length = 1286
Score = 42.4 bits (98), Expect = 0.001
Identities = 41/187 (21%), Positives = 88/187 (47%), Gaps = 24/187 (12%)
Query: 129 DCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRK---NLAEEYL 185
+C ++ +RA K ++ L++ L KL+ ++N + ++++T++++ L ++
Sbjct: 258 ECAQKAAELRASIKEKVELIR-----LKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQ 312
Query: 186 HYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMEL 245
LS A + L+ +NELR + ++ S K ++LK +D++ QM L
Sbjct: 313 GILSA--AHEALLKQVNELRAELKEES-------------KKAVSLKSQLEDVSILQMTL 357
Query: 246 NNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQ 305
+ D+ R + + +K L+ LD+ +S + I QL + +DQ
Sbjct: 358 KEFQERVEDLEKERKL-LNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQ 416
Query: 306 FFSELQE 312
+EL++
Sbjct: 417 LDAELED 423
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 42.4 bits (98), Expect = 0.001
Identities = 58/262 (22%), Positives = 113/262 (43%), Gaps = 31/262 (11%)
Query: 67 DSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQRE--KIRALEPLKAKLV 124
D+ +LQ +++++ ++ + K + ++ + +L Q E +++A P+
Sbjct: 474 DTETHAQLQEMKQLYQASKDELERQKHMYDQLE---QDLLLCQLELKELKASHPIPEDKG 530
Query: 125 TVNEDCNERILAM-RAEEKY-----EISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRK 178
C+ + + +EKY E+ L+ E+ LL+ + EE+ LQ E+ +L
Sbjct: 531 KCANKCDTLLSRLTELQEKYKASQKEMGQLQMEQCELLEDQRRMQEEQGQLQEELHRLTL 590
Query: 179 NLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDL 238
L + L S+ K+ DL EL+ + M Q I +D V ++
Sbjct: 591 PLPKSGLLLKSQELLTKL--EDLCELQLLYQGMQEEQKKLIQNQDCVL---------KEQ 639
Query: 239 TRTQMELNNMK-ANFGDVVPRRDFEM--------QEKTNKDLQEQLDTLRASYEEVRKEH 289
EL K ++F +V+ D + K +K L EQ+ L+ Y+ + +
Sbjct: 640 LEIHEELRRFKESHFQEVLENPDDSKLAKSSKCNRNKQSKLLMEQMQALQVMYDAGQAKQ 699
Query: 290 EILMQLHMSTLKERDQFFSELQ 311
E+L Q L+ER + ++LQ
Sbjct: 700 ELLQQEQGRLLEERKRLQADLQ 721
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 42.4 bits (98), Expect = 0.001
Identities = 73/315 (23%), Positives = 115/315 (36%), Gaps = 58/315 (18%)
Query: 128 EDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEV-------------- 173
E+ N + A + + + E S LKK+ +L + K +EK + +++V
Sbjct: 934 EEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETI 993
Query: 174 ---TKLRKNLAEEYLHYLS----ERDACKILIADLNELRYQREDM--SLAQSPGIWGEDP 224
TK +K L E + L E D L +L Q +D+ SL Q +
Sbjct: 994 AKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLC---- 1049
Query: 225 VKLTLALKMTRQDLTRTQ---MELNNMKANFGDVVPRRDFEMQEKTNK---------DLQ 272
+ L A + DL Q M+ N K + + +++FEM K LQ
Sbjct: 1050 MDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQ 1109
Query: 273 EQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKDVVAG 332
+++ L+A EE+ +E E K+R EL+EI AG
Sbjct: 1110 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE-----------AG 1158
Query: 333 GPERWQMLAEGKNS--------DQLVDVLLEEIGSGLLREKDFFPGLGYGEAIPAFLRFD 384
G Q+ K D L E + LR+K GE I + R
Sbjct: 1159 GATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVK 1218
Query: 385 GLVENKKPSKKDVVN 399
+E +K K +N
Sbjct: 1219 QKLEKEKSELKMEIN 1233
Score = 33.9 bits (76), Expect = 0.49
Identities = 61/263 (23%), Positives = 105/263 (39%), Gaps = 58/263 (22%)
Query: 89 KTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLL 148
K K L + I+ E + A + + +A E ++ L E+ +ER+ +I +
Sbjct: 1110 KKIKELQARIEELEEEIEAERASRAKA-EKQRSDLSRELEEISERLEEAGGATSAQIEMN 1168
Query: 149 KKEKMNLLKLIDKKNEEKISLQSEVTK--LRKNLAEEYLHYLSERDACKILIADLNELRY 206
KK + K+ +++ E+ +LQ E T LRK A D+ L ++ L+
Sbjct: 1169 KKREAEFQKM--RRDLEESTLQHEATAAALRKKHA----------DSVAELGEQIDSLQR 1216
Query: 207 QREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEK 266
++ + +S LKM DL ++ KANF EK
Sbjct: 1217 VKQKLEKEKSE-------------LKMEINDLASNMETVSKAKANF------------EK 1251
Query: 267 TNKDLQEQLDTLRASYEE-VRKEHEILMQ---LHMST------LKERDQFFSEL------ 310
+ L++QL ++ EE R +E+ Q LH + L E+D S+L
Sbjct: 1252 MCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQA 1311
Query: 311 --QEIQRTSTPRPDWTKCKDVVA 331
Q+I+ + TK K +A
Sbjct: 1312 FTQQIEELKRQLEEETKAKSTLA 1334
Score = 30.0 bits (66), Expect = 7.1
Identities = 47/235 (20%), Positives = 93/235 (39%), Gaps = 46/235 (19%)
Query: 95 LSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCN---------ERILAMRAEEKYEI 145
L +KNAYE L H R + L+ ++ + E E++ EK E+
Sbjct: 1485 LFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSEL 1544
Query: 146 --------SLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYL--------- 188
+ L+ E+ +L++ + N+ K + ++ + + L + ++L
Sbjct: 1545 QTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQST 1604
Query: 189 ------SERDACKI---LIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLT 239
S DA +I + DLNE+ Q + + + L+ T+ L
Sbjct: 1605 LDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRN---------LRNTQGILK 1655
Query: 240 RTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQ 294
TQ+ L++ D+ + M E+ +Q +++ LRAS E + ++ Q
Sbjct: 1656 DTQLHLDDAIRGQDDL--KEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQ 1708
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 42.0 bits (97), Expect = 0.002
Identities = 61/277 (22%), Positives = 114/277 (41%), Gaps = 48/277 (17%)
Query: 106 LAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEE 165
L HQR+ LE + K + + + I A AEE+ +EK + + EE
Sbjct: 1436 LDHQRQVASNLEKKQKKFDQLLAE-EKSISARYAEERDRAEAEAREKETKALSLARALEE 1494
Query: 166 KISLQSEVTKLRKNLAEEYLHYLSERD-----------ACKILIADLNELRYQREDMSLA 214
+ + E + K L + +S +D + + L + E+R Q E++
Sbjct: 1495 ALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEEL--- 1551
Query: 215 QSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQ 274
ED ++ T K+ R ++ + MKA F + RD E E+ + L +Q
Sbjct: 1552 -------EDELQATEDAKL------RLEVNMQAMKAQFERDLQTRD-EQNEEKKRLLIKQ 1597
Query: 275 LDTLRASYEEVRKEHEIL------MQLHMSTL--------KERDQFFSELQEIQRTSTPR 320
+ L A E+ RK+ + M++ + L K RD+ +L+++Q
Sbjct: 1598 VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQ---AQM 1654
Query: 321 PDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEEI 357
D+ +++ R ++ A+ K S++ + L EI
Sbjct: 1655 KDYQ--RELEEARASRDEIFAQSKESEKKLKSLEAEI 1689
Score = 39.7 bits (91), Expect = 0.009
Identities = 60/280 (21%), Positives = 116/280 (41%), Gaps = 31/280 (11%)
Query: 49 EELENYLRKELLLLDLGTDSTQELRLQPYREIFEF---FIEDFKTYKPLLSSIKNAYEGM 105
EELE L+ EL T + QELR + +E+ E E+ K ++ + ++ +
Sbjct: 1146 EELEA-LKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATA 1204
Query: 106 LAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEE 165
L E++ + KA L + + E K + +K E + K +D + +E
Sbjct: 1205 LEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKV-LQQVKAESEHKRKKLDAQVQE 1263
Query: 166 KISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGI-WGEDP 224
+ SE +LR LAE+ +E D L+ + A+ GI + +D
Sbjct: 1264 LHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEE-------------AEKKGIKFAKDA 1310
Query: 225 VKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDF-----EMQEKTNKDLQEQLDTLR 279
L L+ T++ L + N+ + + ++ E +E+ K+L++Q+ L+
Sbjct: 1311 ASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQ 1370
Query: 280 ASYEEVRKE-------HEILMQLHMSTLKERDQFFSELQE 312
+ + +K+ E L + LK+ + L+E
Sbjct: 1371 SQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410
Score = 38.5 bits (88), Expect = 0.020
Identities = 57/288 (19%), Positives = 126/288 (43%), Gaps = 27/288 (9%)
Query: 43 AKPQYLEELENYLRKELLLLDLGTDSTQ--ELRLQPYREIFEFFIEDFKTYKPLLSSIKN 100
AK Q LEE+ + L + + Q + ++Q + + E +++ + + L K
Sbjct: 915 AKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKV 974
Query: 101 AYEGMLAHQREKIRALEPLKAKLVTVNEDCNERI------LAMRAEEKYEISLLKKEKMN 154
E + E+I LE +K + + +RI LA E+ ++ ++ ++
Sbjct: 975 TAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEV 1034
Query: 155 LLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQ----RED 210
++ ++++ +++ + E+ K ++ L E +D L A ++EL+ Q E+
Sbjct: 1035 MISDLEERLKKEEKTRQELEKAKRKLDGETTDL---QDQIAELQAQIDELKLQLAKKEEE 1091
Query: 211 MSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKD 270
+ A + G ++ + ALK+ R+ Q ++ ++ +F R+ EK +D
Sbjct: 1092 LQGALARG--DDETLHKNNALKVVRE----LQAQIAELQEDFESEKASRN--KAEKQKRD 1143
Query: 271 LQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTST 318
L E+L+ L+ E+ +L +R+Q +EL++ T
Sbjct: 1144 LSEELEALKTELEDTLDTTAAQQELR----TKREQEVAELKKALEEET 1187
Score = 36.6 bits (83), Expect = 0.075
Identities = 51/229 (22%), Positives = 103/229 (44%), Gaps = 33/229 (14%)
Query: 101 AYEGMLAHQREK-------IRALEPLKAKLV----TVNEDCNERILAMRAEEKYEISLLK 149
A + LA ++K I +LE K KL+ +++ E+ LA EK + + L+
Sbjct: 1368 ALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTK-NRLQ 1426
Query: 150 KEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEY---LHYLSERDACKILIADLNELRY 206
+E +L +D + + +L+ + K + LAEE Y ERD A+
Sbjct: 1427 QELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDR-----AEAEAREK 1481
Query: 207 QREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEK 266
+ + +SLA++ E+ ++ + + L +L + K + G ++ EK
Sbjct: 1482 ETKALSLARAL----EEALEAKEEFERQNKQLRADMEDLMSSKDDVG-----KNVHELEK 1532
Query: 267 TNKDLQEQLDTLRASYEEVRKE----HEILMQLHMSTLKERDQFFSELQ 311
+ + L++Q++ +R EE+ E + ++L ++ + QF +LQ
Sbjct: 1533 SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQ 1581
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 42.0 bits (97), Expect = 0.002
Identities = 53/221 (23%), Positives = 93/221 (42%), Gaps = 39/221 (17%)
Query: 128 EDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLA--EEYL 185
E+ N + A + + + E S LKK+ +L + K +EK + +++V L + +A +E +
Sbjct: 933 EEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETI 992
Query: 186 HYLS-------------------ERDACKILIADLNELRYQREDM--SLAQSPGIWGEDP 224
LS E D IL +L Q +D+ SL Q +
Sbjct: 993 AKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKL----R 1048
Query: 225 VKLTLALKMTRQDLTRTQ---MELNNMKANFGDVVPRRDFEMQEKTNK---------DLQ 272
+ L A + DL Q M++ N K + + +++FE+ +K LQ
Sbjct: 1049 MDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQ 1108
Query: 273 EQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEI 313
+++ L+A EE+ +E E K+R EL+EI
Sbjct: 1109 KKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEI 1149
Score = 36.6 bits (83), Expect = 0.075
Identities = 52/254 (20%), Positives = 113/254 (44%), Gaps = 40/254 (15%)
Query: 56 RKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRA 115
R+ L + + ++ P+ ++F FK KPLL S + E +A +E+ +
Sbjct: 811 REALFCIQYNVRAFMNVKHWPWMKLF------FKI-KPLLKSAETEKE--MATMKEEFQK 861
Query: 116 LEP-----------LKAKLVTVNEDCNERILAMR--------AEEKYEISLLKKEKMNL- 155
+ L+ K+VT+ ++ N+ L ++ AEE+ E + K ++
Sbjct: 862 TKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAK 921
Query: 156 LKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQRED--MSL 213
+K + ++ EE+ + +E+T ++ L +E + D ++ +A + + ++ E+ +L
Sbjct: 922 IKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 981
Query: 214 AQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQE 273
+ E KL+ K ++ Q L++++A V + K L++
Sbjct: 982 TEEMAGLDETIAKLSKEKKALQE---THQQTLDDLQAEEDKV------NILTKAKTKLEQ 1032
Query: 274 QLDTLRASYEEVRK 287
Q+D L S E+ +K
Sbjct: 1033 QVDDLEGSLEQEKK 1046
Score = 33.1 bits (74), Expect = 0.83
Identities = 46/220 (20%), Positives = 83/220 (37%), Gaps = 46/220 (20%)
Query: 103 EGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKK 162
EG L +++ LE K KL + E + M +++ L+K++ + LI K
Sbjct: 1038 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKI 1097
Query: 163 NEEK---ISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGI 219
+E+ I LQ ++ +L+ + E L E E+ +R + A+
Sbjct: 1098 EDEQAVEIQLQKKIKELQARIEE-----LGE------------EIEAERASRAKAEK--- 1137
Query: 220 WGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLR 279
R DL+R E++ G Q + NK + + LR
Sbjct: 1138 --------------QRSDLSRELEEISERLEEAGGAT-----SAQVELNKKREAEFQKLR 1178
Query: 280 ASYEEVRKEHE----ILMQLHMSTLKERDQFFSELQEIQR 315
EE +HE L + H ++ E + LQ +++
Sbjct: 1179 RDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQ 1218
>gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens]
Length = 676
Score = 41.6 bits (96), Expect = 0.002
Identities = 61/282 (21%), Positives = 115/282 (40%), Gaps = 56/282 (19%)
Query: 62 LDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEPLKA 121
LDLG Q+L+L+ R + D +T L Y A + + ++ LK
Sbjct: 106 LDLG----QQLQLKVQR------LHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKE 155
Query: 122 KLVTVNEDCNERI--LAMRAEEKYEISLLKKEK------MNLLKLIDKKNEEKISLQSEV 173
K+ + + +A+ E+K + +KE+ M+ +++ + SLQ+ +
Sbjct: 156 KIREYEQTLKNQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTAL 215
Query: 174 TKLRKNLAEEYLHYLSER----DACKILIADLN-----------ELRYQREDMSLA---- 214
K R L + Y E D ++++ DL E RE +S A
Sbjct: 216 EKTRTELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSL 275
Query: 215 -------QSPGIWGEDPVKLTLALKMTR---------QDLTRTQMELNNMKANFGDVVPR 258
++P + E + +L +++ +D+ R Q L ++ N + +
Sbjct: 276 QLASQIQKAPDVAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQ 335
Query: 259 RDFEMQEK--TNKDLQEQLDTLRASYEEVRKEHEILMQLHMS 298
+ ++ K T K L+E+L +A YEEV+KE IL + +
Sbjct: 336 LEQQLSAKNSTLKQLEEKLKG-QADYEEVKKELNILKSMEFA 376
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 41.6 bits (96), Expect = 0.002
Identities = 66/285 (23%), Positives = 125/285 (43%), Gaps = 47/285 (16%)
Query: 43 AKPQYLEELENYLRK-ELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNA 101
AK +Y+EE+ + E+ LD + LQ E + +++ T +L +
Sbjct: 155 AKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEE 214
Query: 102 YEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDK 161
A +++ LE A+L + ++ MR E K+E + L KL++K
Sbjct: 215 KGSDGAASSYQLKQLEEQNARL-------KDALVRMRDLSSSE----KQEHVKLQKLMEK 263
Query: 162 KNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWG 221
KN+E V + R+ L EE LS+ + + ++EL+ Q + +
Sbjct: 264 KNQE----LEVVRQQRERLQEE----LSQAE------STIDELKEQVD-------AALGA 302
Query: 222 EDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDF--EMQE---KTNKDLQEQLD 276
E+ V++ +T ++L + ++ ++ GD+ + E+QE +T +L+EQLD
Sbjct: 303 EEMVEM-----LTDRNL-NLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLD 356
Query: 277 TLRASYEEVRKEHEILMQL---HMSTLKERDQFFSELQEIQRTST 318
A E +K E + + T+K+ Q + LQ++ R T
Sbjct: 357 MAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELT 401
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,925,100
Number of Sequences: 37866
Number of extensions: 1158926
Number of successful extensions: 6026
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 332
Number of HSP's that attempted gapping in prelim test: 5215
Number of HSP's gapped (non-prelim): 1061
length of query: 658
length of database: 18,247,518
effective HSP length: 109
effective length of query: 549
effective length of database: 14,120,124
effective search space: 7751948076
effective search space used: 7751948076
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.