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Search of human proteins with 150010604
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150010604 kinesin family member 4B [Homo sapiens]
(1234 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150010604 kinesin family member 4B [Homo sapiens] 2427 0.0
gi|116686122 kinesin family member 4 [Homo sapiens] 2264 0.0
gi|38569484 kinesin family member 21A [Homo sapiens] 461 e-129
gi|83716024 kinesin family member 21B [Homo sapiens] 410 e-114
gi|30794488 kinesin family member 27 [Homo sapiens] 368 e-101
gi|71061468 centromere protein E [Homo sapiens] 320 4e-87
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 309 1e-83
gi|203096856 kinesin family member 7 [Homo sapiens] 305 1e-82
gi|9910266 kinesin family member 15 [Homo sapiens] 304 3e-82
gi|46852174 kinesin family member 3A [Homo sapiens] 301 3e-81
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 296 6e-80
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 296 6e-80
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 285 2e-76
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 285 2e-76
gi|4758650 kinesin family member 5C [Homo sapiens] 284 4e-76
gi|4758646 kinesin family member 3B [Homo sapiens] 281 2e-75
gi|4758648 kinesin family member 5B [Homo sapiens] 280 6e-75
gi|46852172 kinesin family member 13B [Homo sapiens] 279 1e-74
gi|45446749 kinesin family member 5A [Homo sapiens] 277 5e-74
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 276 7e-74
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 275 2e-73
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 275 2e-73
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 275 2e-73
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 275 2e-73
gi|13699824 kinesin family member 11 [Homo sapiens] 271 2e-72
gi|41352705 kinesin family member 3C [Homo sapiens] 267 5e-71
gi|7661878 kinesin family member 14 [Homo sapiens] 263 1e-69
gi|40254834 kinesin family member 1C [Homo sapiens] 263 1e-69
gi|156616271 kinesin family member 19 [Homo sapiens] 256 9e-68
gi|148612831 kinesin family member 18A [Homo sapiens] 239 1e-62
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 2427 bits (6289), Expect = 0.0
Identities = 1234/1234 (100%), Positives = 1234/1234 (100%)
Query: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTE 60
MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTE
Sbjct: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTE 60
Query: 61 QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQ 120
QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQ
Sbjct: 61 QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQ 120
Query: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT
Sbjct: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
Query: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLVD 240
VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLVD
Sbjct: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLVD 240
Query: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDS 300
LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDS
Sbjct: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDS 300
Query: 301 LGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQ 360
LGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQ
Sbjct: 301 LGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQ 360
Query: 361 LQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERI 420
LQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERI
Sbjct: 361 LQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERI 420
Query: 421 ILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET 480
ILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET
Sbjct: 421 ILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET 480
Query: 481 VACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALV 540
VACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALV
Sbjct: 481 VACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALV 540
Query: 541 RKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHK 600
RKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHK
Sbjct: 541 RKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHK 600
Query: 601 LLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEK 660
LLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEK
Sbjct: 601 LLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEK 660
Query: 661 FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQK 720
FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQK
Sbjct: 661 FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQK 720
Query: 721 QREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQ 780
QREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQ
Sbjct: 721 QREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQ 780
Query: 781 LKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQK 840
LKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQK
Sbjct: 781 LKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQK 840
Query: 841 LLDAESEDRPKQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQK 900
LLDAESEDRPKQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQK
Sbjct: 841 LLDAESEDRPKQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQK 900
Query: 901 MLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLV 960
MLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLV
Sbjct: 901 MLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLV 960
Query: 961 STLQCQDEELEKMREVCEQNQQLLQENEIIKQKLILLQVASRQKHLPNDTLLSPDSSFEY 1020
STLQCQDEELEKMREVCEQNQQLLQENEIIKQKLILLQVASRQKHLPNDTLLSPDSSFEY
Sbjct: 961 STLQCQDEELEKMREVCEQNQQLLQENEIIKQKLILLQVASRQKHLPNDTLLSPDSSFEY 1020
Query: 1021 IPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDEEWKPTKLVKV 1080
IPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDEEWKPTKLVKV
Sbjct: 1021 IPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDEEWKPTKLVKV 1080
Query: 1081 SRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCSCDPTKCRNRQQGKDSLGTVEQTQDSEG 1140
SRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCSCDPTKCRNRQQGKDSLGTVEQTQDSEG
Sbjct: 1081 SRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCSCDPTKCRNRQQGKDSLGTVEQTQDSEG 1140
Query: 1141 SFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDMEQVLSKKTAPAPSPFDLPESKHGAT 1200
SFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDMEQVLSKKTAPAPSPFDLPESKHGAT
Sbjct: 1141 SFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDMEQVLSKKTAPAPSPFDLPESKHGAT 1200
Query: 1201 EYQQNKPPGKKKKRALASNTSFFSGCSPIEEEAH 1234
EYQQNKPPGKKKKRALASNTSFFSGCSPIEEEAH
Sbjct: 1201 EYQQNKPPGKKKKRALASNTSFFSGCSPIEEEAH 1234
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 2264 bits (5866), Expect = 0.0
Identities = 1157/1234 (93%), Positives = 1187/1234 (96%), Gaps = 2/1234 (0%)
Query: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTE 60
MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGE QVVVGTDKSFTYDFVFDP TE
Sbjct: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTE 60
Query: 61 QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQ 120
QEEVFN AVAPLIKG+FKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVG+IPRVIQ
Sbjct: 61 QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQ 120
Query: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT
Sbjct: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
Query: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLVD 240
VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTIS+EQRKKSDKN SFRSKLHLVD
Sbjct: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVD 240
Query: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDS 300
LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKG FVPYRDSKLTRLLQDS
Sbjct: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDS 300
Query: 301 LGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQ 360
LGGNSHTLMIACVSPADSNLEETL+TLRYADRARKIKNKPIVNIDP TAELNHLKQQVQQ
Sbjct: 301 LGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQ 360
Query: 361 LQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERI 420
LQVLLLQAHGGTLPGSI EPSENLQSLMEKNQSLVEENEKLSR LS+AAGQTAQMLERI
Sbjct: 361 LQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERI 420
Query: 421 ILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET 480
ILTEQ NEK+NAKLEELRQH ACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET
Sbjct: 421 ILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDET 480
Query: 481 VACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALV 540
VAC AAAIDTAVE+EAQVETSPETSRSSDAFTTQHAL QAQMSKE+VELN ALALKEAL
Sbjct: 481 VACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALA 540
Query: 541 RKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHK 600
RKMTQND+QLQPIQ+QYQDNIK LELEVINLQKEKEELV ELQTAKK+ NQAKLSE R K
Sbjct: 541 RKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRK 600
Query: 601 LLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEK 660
LQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEI MMKNQRVQLMRQMKEDAEK
Sbjct: 601 RLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEK 660
Query: 661 FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQK 720
FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQS+VLRRKTEEAAAANKRLKDALQK
Sbjct: 661 FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQK 720
Query: 721 QREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQ 780
QREV DKRKETQS G EG AARV+NWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDV Q
Sbjct: 721 QREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQ 780
Query: 781 LKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQK 840
LKEKKES ENPPPKLR+ TFSL+EV GQV ESED ITKQIESLETEME RSAQIADLQQK
Sbjct: 781 LKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQK 840
Query: 841 LLDAESEDRPKQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQK 900
LLDAESEDRPKQ WENIATILEAKCALKYLIGELVSSKI V+KLE+SL+QSK SCADMQK
Sbjct: 841 LLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQK 900
Query: 901 MLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLV 960
MLFEE+NHF+EIETELQAELVRMEQQHQEKVLYL+SQLQ+SQMAEKQLE+S SEKEQQL+
Sbjct: 901 MLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLL 960
Query: 961 STLQCQDEELEKMREVCEQNQQLLQENEIIKQKLILLQVASRQKHLPNDTLLSPDSSFEY 1020
STL+CQDEELEKMREVCEQNQQLL+ENEIIKQKL LLQVASRQKHLP DTLLSPDSSFEY
Sbjct: 961 STLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEY 1020
Query: 1021 IPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDEEWKPTKLVKV 1080
+PPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHE DGDGD DEGDDEEWKPTKLVKV
Sbjct: 1021 VPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHE--DGDGDDDEGDDEEWKPTKLVKV 1078
Query: 1081 SRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCSCDPTKCRNRQQGKDSLGTVEQTQDSEG 1140
SRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDC CDPTKCRNRQQGKDSLGTVE+TQDSEG
Sbjct: 1079 SRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCCCDPTKCRNRQQGKDSLGTVERTQDSEG 1138
Query: 1141 SFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDMEQVLSKKTAPAPSPFDLPESKHGAT 1200
SFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCD+EQVLSKKT PAPSPFDLPE KH AT
Sbjct: 1139 SFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDVEQVLSKKTPPAPSPFDLPELKHVAT 1198
Query: 1201 EYQQNKPPGKKKKRALASNTSFFSGCSPIEEEAH 1234
EYQ+NK PGKKKKRALASNTSFFSGCSPIEEEAH
Sbjct: 1199 EYQENKAPGKKKKRALASNTSFFSGCSPIEEEAH 1232
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 461 bits (1185), Expect = e-129
Identities = 336/1087 (30%), Positives = 543/1087 (49%), Gaps = 184/1087 (16%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKAV 69
VRVA+R RP + KE EGC +C S PGE QV +G DK+FT+D+VFD ++QE+++ + +
Sbjct: 10 VRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCI 69
Query: 70 APLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEIDKK 129
LI+G F+GYNATV AYGQTG+GKTY+MG + E +GII R ++ LFK I++K
Sbjct: 70 EKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEE-ELGIISRAVKHLFKSIEEK 128
Query: 130 SDF---------EFTLKVSYLEIYNEEILDLLCPSRE------KAQINIREDPKEGIKIV 174
+F + +LE+YNEE+LDL +R+ K+ I I ED GI V
Sbjct: 129 KHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGIYTV 188
Query: 175 GLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK---------- 224
G+T +TV + + CL+ G SRT AST MN QSSRSHAIFTI + Q +
Sbjct: 189 GVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDADNA 248
Query: 225 ----------KSDKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVI 274
+ ++ + +K H VDLAGSER K+T A G+R KEGI+IN GLL LGNVI
Sbjct: 249 TDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVI 308
Query: 275 SALGD-DKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRA 333
SALGD K+ + VPYRDSKLTRLLQDSLGGNS T+MIACVSP+D + ETL+TL+YA+RA
Sbjct: 309 SALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRA 368
Query: 334 RKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQ 393
R IKNK +VN D + ++N L+ ++ +LQ+ L++ G I+ E E++ + +N
Sbjct: 369 RNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTG--KRIIDEEGVESINDMFHENA 426
Query: 394 SLVEENEKLSRCLSKAAGQTAQMLERIIL-----------------TEQVNEKLNAKLEE 436
L EN L R KA +T L I E+++ +++ ++E
Sbjct: 427 MLQTENNNL-RVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKE 485
Query: 437 LRQHVACKLDLQKLVETLED-----------------------QELKENVEIICNLQQLI 473
+ A L+ + + E L KE +EII ++ +
Sbjct: 486 IEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKDL 545
Query: 474 TQL------SDETVACTAAAIDTAVEE------------EAQVETSPETS---------- 505
+L ++VA DT E+ E +VE S E S
Sbjct: 546 EKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEE 605
Query: 506 ------------RSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPI 553
SD+ + + A +QA ++ E +A+K+ L+ ++ + +LQ +
Sbjct: 606 EEEDDIDGGESSDESDSESDEKANYQADLANITCE----IAIKQKLIDELENSQKRLQTL 661
Query: 554 QFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQ--AKLSEHRHKLLQELEGQIAD 611
+ QY++ + L+ ++ + Q E++++++ L + + + K+ K LQ + ++
Sbjct: 662 KKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQR 721
Query: 612 LKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKE 671
L+ E ++LLK + E+ + KL Q++ MK +V+LM+QMKE+ EK R + ++++E
Sbjct: 722 LQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNRE 781
Query: 672 VIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQK-----QREVTD 726
+ QLK+ RKR ++L LE + Q VLRRKTEE A ++++ K R+++
Sbjct: 782 IAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSS 841
Query: 727 KRKETQSHGKEGIAARV---RNWLGNEIEVMVSTEEA----------------------- 760
Q G A R ++ + V+ +A
Sbjct: 842 SDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVF 901
Query: 761 ------------KRHLNDLLEDRKILAQ---DVVQLKEKKESRENPPPKLRKCTFSLSEV 805
+R + D++ + ++ D+ +L +++E KL K + +
Sbjct: 902 ISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKE 961
Query: 806 HGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWE-----NIATI 860
+G+ ++ I +++ESL ++ + I+D Q ++ E + + N T+
Sbjct: 962 NGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTL 1021
Query: 861 LEAKCALKYLIG-------ELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIE 913
EA+ L + + + + + LE L+Q++ + A ++LF +E+
Sbjct: 1022 TEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELN 1081
Query: 914 TELQAEL 920
EL A L
Sbjct: 1082 PELDALL 1088
Score = 44.3 bits (103), Expect = 7e-04
Identities = 82/418 (19%), Positives = 176/418 (42%), Gaps = 37/418 (8%)
Query: 586 KKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKL-KESTERTVSKLNQEIWMMK 644
K VNQ + S+ + L +I L+ +L E ++ E +++ + E M++
Sbjct: 374 KVMVNQDRASQQ----INALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQ 429
Query: 645 NQRVQL---MRQMKEDAEKFR-QWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVL 700
+ L ++ M+E + R + Q + + R + E+ + ++ K+ L
Sbjct: 430 TENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDL 489
Query: 701 RRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEA 760
R K E+ A N+ L+ L R ++ G + L ++ E + + A
Sbjct: 490 RAKLLESEAVNENLRKNLT--------RATARAPYFSGSSTFSPTILSSDKETIEIIDLA 541
Query: 761 KRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQI 820
K+ L L K + V ++ ++ + +K +SE LE E+ ++++
Sbjct: 542 KKDLEKLKRKEKRKKKSVAGKEDNTDTDQE-----KKEEKGVSERENNELEVEE--SQEV 594
Query: 821 ESLETEMELRSAQIADLQ--QKLLDAESEDRPKQCWENIATILEAKCALKY-LIGELVSS 877
E E E + D+ + +++SE K ++ + + A+K LI EL +S
Sbjct: 595 SDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENS 654
Query: 878 KIHVTKL----ENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLY 933
+ + L E L + D Q + + +E+ + + ++ ++++K+
Sbjct: 655 QKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQA 714
Query: 934 LVSQLQESQMAEKQ---LEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQQLLQENE 988
+ +LQ Q A+K+ L K+ S+ E+QL + Q + +E + +Q+ +E E
Sbjct: 715 MNKELQRLQAAQKEHARLLKNQSQYEKQL---KKLQQDVMEMKKTKVRLMKQMKEEQE 769
Score = 38.1 bits (87), Expect = 0.052
Identities = 50/277 (18%), Positives = 118/277 (42%), Gaps = 35/277 (12%)
Query: 805 VHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDR--PKQCWENIATILE 862
+ +V+ ++D ++QI +L +E I LQ +L++ ++ R ++ E+I +
Sbjct: 371 IKNKVMVNQDRASQQINALRSE-------ITRLQMELMEYKTGKRIIDEEGVESINDMFH 423
Query: 863 AKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVR 922
L+ L ++ + ++ ++ ++ + +++ ++ NH E E+
Sbjct: 424 ENAMLQTENNNL---RVRIKAMQETVDALRSR---ITQLVSDQANHVLARAGEGNEEISN 477
Query: 923 MEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQ---------LVSTLQCQDEELEKM 973
M + +++ L ++L ES+ + L K+ + + T+ D+E ++
Sbjct: 478 MIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEI 537
Query: 974 REVCEQNQQLLQENEIIKQKLILLQVASRQKHLPNDTLLSPDSSFEYIPPKPKPSRVKEK 1033
++ +++ + L+ E K+K VA ++ + D + E
Sbjct: 538 IDLAKKDLEKLKRKEKRKKK----SVAGKEDNTDTDQEKKEEKGVS-------ERENNEL 586
Query: 1034 FLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDE 1070
+E+S ++ D + E E +D DG SDE D E
Sbjct: 587 EVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSE 623
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 410 bits (1054), Expect = e-114
Identities = 331/1136 (29%), Positives = 537/1136 (47%), Gaps = 209/1136 (18%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKAV 69
V+VA+R RP + KE EGC +C S PGE QV++G DK+FTYDFVFD T QE++++ V
Sbjct: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCV 68
Query: 70 APLIKGIFKGYNATVLAYGQTGSGKTYSMGGAY---TAEQENEPTVGIIPRVIQLLFKEI 126
+ LI+G F+GYNATVLAYGQTG+GKTY+MG + T+E+E GIIPR I LF I
Sbjct: 69 SKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQ----GIIPRAIAHLFGGI 124
Query: 127 DKK---------SDFEFTLKVSYLEIYNEEILDLLCPSRE------KAQINIREDPKEGI 171
++ + EF + +LE+YNEEILDL +R+ ++ I I ED GI
Sbjct: 125 AERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGI 184
Query: 172 KIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK------- 224
G+T + + + + CL+QG SRT AST MN QSSRSHAIFTI + Q +
Sbjct: 185 YTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDL 244
Query: 225 -------------KSDKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLG 271
S + + +K H VDLAGSER K+T A G+R KEGI+IN GLL LG
Sbjct: 245 VNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALG 304
Query: 272 NVISALGD-DKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYA 330
NVISALGD KK VPYRDSKLTRLLQDSLGGNS T+MIACVSP+D + ETL+TL+YA
Sbjct: 305 NVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYA 364
Query: 331 DRARKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLME 390
+RAR IKNK +VN D + +++ L+ ++ +LQ+ L++ G I + +E L
Sbjct: 365 NRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAG--KRVIGEDGAEGYSDLFR 422
Query: 391 KNQSLVEE------------------NEKLSRCLSKAAG--------------------- 411
+N L +E N ++++ +S+ A
Sbjct: 423 ENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYI 482
Query: 412 -QTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETL---EDQELKENVEIIC 467
+ ++ +++ +E +NE L L L +++ E+I
Sbjct: 483 REIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIR 542
Query: 468 NLQQLITQLSDETVACTAAAID-------TAVEEEAQVETSPETSRSSDAFTTQHALHQA 520
+Q + +L + V + + +++E ET + + + +
Sbjct: 543 RAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEE 602
Query: 521 QMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQK---EKEE 577
+ ++ E + + +E+LV +D+ + + +Q ++ +L E+ QK E E
Sbjct: 603 EGREDEDEDSGS---EESLV----DSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELEN 655
Query: 578 LVRELQTAKKNVNQA----------------------------------KLSEHRHKLLQ 603
R LQT K + K+ K L+
Sbjct: 656 SQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLR 715
Query: 604 ELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQ 663
E+ + L+ E ++LLK + ER + KL E+ MK +V LM+QM+E+ ++ R
Sbjct: 716 EMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRL 775
Query: 664 WKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLK-------- 715
+ K+++E+ QLK+ R++++++ LE ++Q VLRRKT+E +A + K
Sbjct: 776 VETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAG 835
Query: 716 ------DALQKQREVTDKRKETQSH-GKEGIAARVRNW-------LGNEIEVMVS----- 756
L EV+ +++ G +++ VR W LG+ V+
Sbjct: 836 RAGLKPPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPA 895
Query: 757 --------------------TEEAKRHLNDLLEDRKI---LAQDVVQLKEKKESRENPPP 793
+ +R + D++ R L D+ +L +K+E
Sbjct: 896 RKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQE 955
Query: 794 KLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQC 853
LR+ L + + + ++IE L ++ + I D Q ++ + E+ ++
Sbjct: 956 ALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIV--QLEETKEEL 1013
Query: 854 WENIATILEAKCAL---KYLIGELVSSKI-----------HVTKLENSLRQSKASCADMQ 899
+++ + C+L + L+ + + I + LE LRQ+ + +
Sbjct: 1014 DSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQN 1073
Query: 900 KMLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEK 955
+L + +E ELQA + ++Q++ Y + + S+ +E +S + K
Sbjct: 1074 HLLLDALREKAEAHPELQALIYNVQQENG----YASTDEEISEFSEGSFSQSFTMK 1125
Score = 35.0 bits (79), Expect = 0.44
Identities = 36/167 (21%), Positives = 78/167 (46%), Gaps = 11/167 (6%)
Query: 889 RQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQL 948
R+S A ++ +++N E E + E ++ E+ + ++S E +
Sbjct: 560 RKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLV 619
Query: 949 EKSASEKEQQL-----VSTLQCQDEELEKMREVCEQNQQLLQE-NEIIKQKLILLQVASR 1002
+ + +E+++ ++ L C+ E +K+ + E +Q+ LQ ++KLILLQ R
Sbjct: 620 DSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIR 679
Query: 1003 QKHLPNDTLLSPDSSFEYIPPKPKPSRVK----EKFLEQSMDIEDLK 1045
L D +L S+ E + K +++K ++ E + D++ L+
Sbjct: 680 DTQLERDRVLQNLSTMECY-TEEKANKIKADYEKRLREMNRDLQKLQ 725
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 368 bits (945), Expect = e-101
Identities = 321/1089 (29%), Positives = 506/1089 (46%), Gaps = 168/1089 (15%)
Query: 8 IPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNK 67
IPV+VA+R RPL+ KE Q+C+ +P QV++G D+ FT+DFVF + Q+EV+N
Sbjct: 4 IPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVYNT 63
Query: 68 AVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEID 127
+ PL+ + +GYNATV AYGQTGSGKTY++GG + A E GIIPR IQ +F+ I
Sbjct: 64 CIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVV-EGQKGIIPRAIQEIFQSIS 122
Query: 128 KKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDT 187
+ +F +KVSY+E+Y E++ DLL ++IRED K IVG E V A +
Sbjct: 123 EHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAGEV 182
Query: 188 VSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCS---------FRSKLHL 238
+S LE GN +R +T MN SSRSHAIFTISI Q K+ + SK H
Sbjct: 183 MSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKFHF 242
Query: 239 VDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDD-KKGSFVPYRDSKLTRLL 297
VDLAGSER KT G+R KE I IN GLL LGNVISALGD +K S +PYRD+K+TRLL
Sbjct: 243 VDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITRLL 302
Query: 298 QDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQ 357
+DSLGG++ T+MI CVSP+ SN +E+L++L+YA+RAR I+NKP VN P + ++ ++ +
Sbjct: 303 KDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESDRIDEMEFE 362
Query: 358 VQQL-QVLLLQAHGGTLPGSINAEPS---ENLQSLMEKNQSLVEENEKLSRCLSKAAGQT 413
++ L + L Q G + IN E S + SL E+ L E C+ +A
Sbjct: 363 IKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFL 422
Query: 414 AQMLERIILTEQVNEKL-----------------------NAKLEELRQHVA-------- 442
+ + + L E+ KL A LEE QHV
Sbjct: 423 VDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEEGPQHVTVLQLKREL 482
Query: 443 ----CKLDLQKLV---ETLEDQELKENVEI-------------------------ICNLQ 470
C L ++V + LE +ELK V++ I Q
Sbjct: 483 KKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQ 542
Query: 471 QLITQLSDETVACTAAAIDTAVEE--EAQVETSPETSRSSDAFTTQ--HALH--QAQMSK 524
L+ QLS+E + +A E + PE + F T H ++ Q S+
Sbjct: 543 LLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDSR 602
Query: 525 EVVELNNALALKEALVRKMTQN-------DNQLQPIQFQYQDNIKNLE------------ 565
+V +L T++ + Q + + Q+ DN + E
Sbjct: 603 KVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCR 662
Query: 566 --------------LEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIAD 611
+E+ + Q E ++ E + K + Q + KL + E + +
Sbjct: 663 SRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKL-KNSERILTE 721
Query: 612 LKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKE 671
K+K+ E + +K+KE + + K + + Q + +++ DAE+ + + K+
Sbjct: 722 AKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQ 781
Query: 672 VIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKET 731
+ +L+ +D +KL++ F+K+ + + + LQK+++ + K
Sbjct: 782 LQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQ-----------VLQKKQQDSKKLASL 830
Query: 732 QSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENP 791
++ NE+E V D ++ +KI Q +L+E+ E R+
Sbjct: 831 SIQNEK---------RANELEQSV----------DHMKYQKIQLQR--KLREENEKRKQL 869
Query: 792 PPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSA--------QIADLQQKLLD 843
+++ + E+ + + E K + ++ R Q D Q+K LD
Sbjct: 870 DAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLD 929
Query: 844 AESED--RPKQCWENIATILEAKCALKYLIGELVSSKIHVTKLEN-SLRQSKASCADMQK 900
E E +Q E + L+ + A+ L+ K H LEN LR S+A D K
Sbjct: 930 EEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSH---LENKKLRSSQALNTDSLK 986
Query: 901 MLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLV 960
+ + +E EL + V+++ E+ + Q++ Q + QL+K +++L
Sbjct: 987 I----STRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLK 1042
Query: 961 STLQCQDEE 969
+ EE
Sbjct: 1043 NGRVLSPEE 1051
Score = 87.8 bits (216), Expect = 6e-17
Identities = 141/642 (21%), Positives = 277/642 (43%), Gaps = 101/642 (15%)
Query: 466 ICNLQQLITQLSDETVACTAAAIDTAVE--EEAQVETSPETSRSSDAFTTQHALHQAQMS 523
+C+L +L + DET D ++ +E+Q E + + ++S+ T+
Sbjct: 673 VCSLVEL-SDTQDETQKSDLENEDLKIDCLQESQ-ELNLQKLKNSERILTE-------AK 723
Query: 524 KEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLE-------LEVINLQKEKE 576
+++ EL + +KE L++++ + N + + QY + LE +E+I QK+ +
Sbjct: 724 QKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQ 783
Query: 577 ELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKL 636
EL E + + KL + K + + ++ L+KK + KL L E+ ++L
Sbjct: 784 EL--ENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANEL 841
Query: 637 NQEIWMMKNQRVQLMRQMKEDAEKFRQW------KQKKDKEVIQLKE------------- 677
Q + MK Q++QL R+++E+ EK +Q Q+K KE IQLK
Sbjct: 842 EQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKE-IQLKTGQEEGLKPKAEDL 900
Query: 678 -----RDRKRQYELLKLERNFQKQSSVL----------RRKTEEAAAANKR------LKD 716
+ RK + + + +Q L R++ EE A K+ K+
Sbjct: 901 DACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKE 960
Query: 717 ALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQ 776
AL +++ + +K S + ++ L N +E +S + + + E KI Q
Sbjct: 961 ALLQEKSHLENKKLRSSQALNTDSLKISTRL-NLLEQELSEKNVQLQTSTAEEKTKISEQ 1019
Query: 777 DVVQLKEK---KESRENPPPKLRKCTFSLSEVHGQVLESED-----CITKQIESLETEME 828
V KEK ++ R N KL+ +G+VL E+ + + IE+LE +E
Sbjct: 1020 VEVLQKEKDQLQKRRHNVDEKLK---------NGRVLSPEEEHVLFQLEEGIEALEAAIE 1070
Query: 829 LRSAQIADLQQKLLDAESEDRPK---QCWENIATI--LEAKCALKYLIGELVSSKIHVTK 883
R+ I + +QK L A + + E +A + +E + L ++V+ + K
Sbjct: 1071 YRNESIQN-RQKSLRASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERK 1129
Query: 884 LENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQM 943
+ + K + M+ E ++ ++ + L +++H++K+ L+ +E Q
Sbjct: 1130 QQLYNEEMKMKVLERDNMVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKE-QD 1188
Query: 944 AEKQLE--KSASEKEQQLVSTLQCQDEELEKMREVCEQNQQLLQENEIIKQKLILLQVAS 1001
E +E K+ +K QQL +++L ++ +++ L+E + + I Q+A
Sbjct: 1189 GEGIMETFKTYEDKIQQL-------EKDLYFYKKTSRDHKKKLKE---LVGEAIRRQLAP 1238
Query: 1002 RQKHLPNDTLLSPDSS---FEYIPPKPKPSRVKEKFLEQSMD 1040
+ D +L P+ E + +P +K E+ MD
Sbjct: 1239 SEYQEAGDGVLKPEGGGMLSEELKWASRPESMKLSGREREMD 1280
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 320 bits (821), Expect = 4e-87
Identities = 299/1031 (29%), Positives = 482/1031 (46%), Gaps = 127/1031 (12%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTD--KSFTYDFVFDPCTEQEEVFNK 67
V V +R RPL +E S G + + + V+ D KSF +D VF + V+ +
Sbjct: 7 VAVCVRVRPLNSREESLG-ETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNVYEE 65
Query: 68 AVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEID 127
AP+I +GYN T+ AYGQT SGKTY+M G+ E +G+IPR I +F++I
Sbjct: 66 IAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGS-------EDHLGVIPRAIHDIFQKIK 118
Query: 128 KKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDT 187
K D EF L+VSY+EIYNE I DLLC +++ + IRED + + LTE+ V +
Sbjct: 119 KFPDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMA 178
Query: 188 VSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSD-KNCSFR---SKLHLVDLAG 243
+ + +G SR T MN +SSRSH IF + +E R+K + NC S L+LVDLAG
Sbjct: 179 LKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVSHLNLVDLAG 238
Query: 244 SERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDSLGG 303
SER +T A G RLKEG NINR L LG VI L D + G F+ YRDSKLTR+LQ+SLGG
Sbjct: 239 SERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGG 298
Query: 304 NSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVN-IDPHTAELNHLKQQVQQLQ 362
N+ T +I ++P + +ETL+ L++A A+ +KN P VN + A L ++++ L+
Sbjct: 299 NAKTRIICTITPV--SFDETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLK 356
Query: 363 VLLLQAHGGTLPGSINAEPSENLQSLMEKNQ--SLVEENEKLSRCLSKAAGQTAQMLERI 420
L + E MEK+Q L+EE + L K + + L R+
Sbjct: 357 KQLEEV------------SLETRAQAMEKDQLAQLLEEKD----LLQKVQNEKIENLTRM 400
Query: 421 ILTEQ---VNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQL- 476
++T + ++L AK + R+ C + K+ + + I +L L
Sbjct: 401 LVTSSSLTLQQELKAKRK--RRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLL 458
Query: 477 --SDETVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALA 534
DE+V + ++ +++E +P T L+Q + ELN+ A
Sbjct: 459 REIDESVCSESDVFSNTLDTLSEIEWNPATK----------LLNQENIES---ELNSLRA 505
Query: 535 LKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKL 594
+ LV Q + + ++ + ++ E E + + +K++ E+Q + N L
Sbjct: 506 DYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQ---EMQLIHEISNLKNL 562
Query: 595 SEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQL-MRQ 653
+H Q+LE NE S ++L E + KL + I K + +++ +
Sbjct: 563 VKHAEVYNQDLE----------NELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSY 612
Query: 654 MKEDAEKFRQWKQKK-DKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANK 712
E E +Q KQ D E + L D KR+ L+ E + L+ K +E A K
Sbjct: 613 SLESIEDPKQMKQTLFDAETVAL---DAKRESAFLRSE------NLELKEKMKELATTYK 663
Query: 713 RLKDALQ--------KQREVTDKRKETQSHGKE------GIAARVRNWLGNEIEVMVSTE 758
++++ +Q K++ D KE QS E I +V L +E+
Sbjct: 664 QMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKIT 723
Query: 759 EAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITK 818
+ ++ LN +E+ + L ++V+ L E K S + +LRK SE + +D +
Sbjct: 724 DLQKELNKEVEENEALREEVILLSELK-SLPSEVERLRKEIQDKSEELHIITSEKDKLFS 782
Query: 819 QIESLETEMELRSAQIADLQQKLLDAESEDR-PKQCWENIATILEAKCALKYLIGELVSS 877
++ E+ ++ +I + L +S + Q ++N T L KY +
Sbjct: 783 EVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKT-LHMDFEQKYKM------ 835
Query: 878 KIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQ 937
LE + R ++ L +E F L+ EL Q+ QEK + +
Sbjct: 836 -----VLEENERMNQEIV-----NLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQER 885
Query: 938 LQESQMAEKQLEKSAS-----EKEQQLVSTLQCQDEELEKMREVCEQNQQLLQENEIIKQ 992
L E + ++QLE S E+E+ L++ EK+++ E+ + L QE + +KQ
Sbjct: 886 LNEMEQLKEQLENRDSTLQTVEREKTLIT---------EKLQQTLEEVKTLTQEKDDLKQ 936
Query: 993 KLILLQVASRQ 1003
LQ+ Q
Sbjct: 937 LQESLQIERDQ 947
Score = 97.1 bits (240), Expect = 9e-20
Identities = 171/728 (23%), Positives = 319/728 (43%), Gaps = 93/728 (12%)
Query: 318 SNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSI 377
SN +TLS + + + A K+ N+ NI+ +ELN L+ L + Q +
Sbjct: 473 SNTLDTLSEIEW-NPATKLLNQE--NIE---SELNSLRADYDNLVLDYEQ---------L 517
Query: 378 NAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERI-----------ILTEQV 426
E E L EKN ++E E L R K Q Q++ I + + +
Sbjct: 518 RTEKEEMELKLKEKND--LDEFEALERKTKK--DQEMQLIHEISNLKNLVKHAEVYNQDL 573
Query: 427 NEKLNAKLEELRQHVACKLDLQKLVETLEDQELKE-------NVEIICNLQQLITQLSD- 478
+L++K+E LR+ + ++KL E ++ Q+L+ ++E I + +Q+ L D
Sbjct: 574 ENELSSKVELLREK---EDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDA 630
Query: 479 ETVACTAAAIDTAVEEE--AQVETSPETSRSSDAFTTQHALHQAQMS---KEVVELNNAL 533
ETVA A + E E E + + L+Q+Q+ K V+L L
Sbjct: 631 ETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKEL 690
Query: 534 ALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELE--VINLQKEKEELVRELQTAKKNV-- 589
+ K+T + P +D + NLELE + +LQKE + V E + ++ V
Sbjct: 691 QSAFNEITKLTSLIDGKVP-----KDLLCNLELEGKITDLQKELNKEVEENEALREEVIL 745
Query: 590 --NQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQR 647
L +L +E++ + +L +E+ KL E V L +EI K+
Sbjct: 746 LSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDL 805
Query: 648 VQLMRQMKEDAEKFRQWKQK----KDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRK 703
K ++F+ +K + K + L+E +R Q E++ L + QK S L
Sbjct: 806 ATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQ-EIVNLSKEAQKFDSSLGAL 864
Query: 704 TEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRH 763
E + + L++ K REV ++ E + KE + R E E + TE+
Sbjct: 865 KTELSYKTQELQE---KTREVQERLNEMEQL-KEQLENRDSTLQTVEREKTLITEK---- 916
Query: 764 LNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQV---LESEDCITKQI 820
L LE+ K L Q+ LK+ +ES + +L+ S++H V +++++ + +
Sbjct: 917 LQQTLEEVKTLTQEKDDLKQLQESLQIERDQLK------SDIHDTVNMNIDTQEQLRNAL 970
Query: 821 ESLETEME----LRSAQIADLQQKLLDAESEDRPKQCWENIATILEAKCALKYLIGELVS 876
ESL+ E L+S ++ + L E+ K ++ ++ K L+ + ++
Sbjct: 971 ESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLT 1030
Query: 877 SKIHVTKLEN------SLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEK 930
+ + ++ SL Q K M + + E+ +++T+L+ E + M ++QE+
Sbjct: 1031 ADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKE---QLKTDLK-ENIEMTIENQEE 1086
Query: 931 VLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQQLLQENEII 990
+ L +L++ Q Q + A +KE +L T E EK++E +Q Q+ Q+ +
Sbjct: 1087 LRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNV 1146
Query: 991 KQKLILLQ 998
++++ +Q
Sbjct: 1147 QEEMSEMQ 1154
Score = 85.1 bits (209), Expect = 4e-16
Identities = 141/673 (20%), Positives = 291/673 (43%), Gaps = 97/673 (14%)
Query: 377 INAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEE 436
I A + + L + L E E + + +TAQ I+ Q EK + KL+E
Sbjct: 1226 IEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQ-----IINTQDLEKSHTKLQE 1280
Query: 437 LRQHVACKLDLQKLVETLEDQELKENVEIICNLQQ------LITQLSDETVACTAAAID- 489
++ E+QEL NV+ + Q+ L+T+ S + T A I+
Sbjct: 1281 ------------EIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEM 1328
Query: 490 -----TAVEEEAQVETSPETSRSSDAFTTQHALH------QAQMSKEVVELNNALALKEA 538
+E+Q E T + T + AL + + + + ++ + + +E
Sbjct: 1329 ERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQ 1388
Query: 539 LVRKMTQNDNQLQPI-----QFQYQDN-IKNLELEVINLQKEKEELVRELQTAKKNVNQA 592
+ M + DN+ I QF+ +D+ + +E+E++ L K +E E+++ A
Sbjct: 1389 SLN-MKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSV------A 1441
Query: 593 KLSEHRHKLLQELEGQIADLKKKLNE-QSKLLKLKESTERTVSKLNQEIWMMKNQRVQLM 651
K + +L + L+ + LK+ + E +K L+ +E + L ++ + RV L
Sbjct: 1442 KEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLS 1501
Query: 652 RQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAAN 711
+ E + +Q + DK +++E K + +K Q++ + L++ E A +
Sbjct: 1502 EKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKD 1561
Query: 712 KRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLE-D 770
L+ K E+T++ +E+Q EI++M+ +E + + + L+ +
Sbjct: 1562 SALQSIESKMLELTNRLQESQ----------------EEIQIMIKEKEEMKRVQEALQIE 1605
Query: 771 RKILAQDVVQLKEK-KESRENPPPKLR-----------------KCTFSLSEVHGQVLES 812
R L ++ ++ K KES+E L+ K F +++ + +E+
Sbjct: 1606 RDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIET 1665
Query: 813 EDCITKQI--ESLETEMELRSAQIADLQ--QKLLDAESEDRPKQCWENIATILEAKCALK 868
E+ QI E+LE EM + + DL+ ++ L E + + E I LE + LK
Sbjct: 1666 ENIRLTQILHENLE-EMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELK 1724
Query: 869 YLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAEL------VR 922
+ L + + KL + + ++MQK L + + ++Q EL ++
Sbjct: 1725 IVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLK 1784
Query: 923 MEQQHQEKVLYLVSQLQES-QMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQ 981
+Q+ +K+ +VS+ + +K LE S + K Q+ + L+ + +L +++ + Q
Sbjct: 1785 EQQETIDKLRGIVSEKTDKLSNMQKDLENS-NAKLQEKIQELKANEHQLITLKKDVNETQ 1843
Query: 982 QLLQENEIIKQKL 994
+ + E E +K+++
Sbjct: 1844 KKVSEMEQLKKQI 1856
Score = 77.8 bits (190), Expect = 6e-14
Identities = 180/893 (20%), Positives = 364/893 (40%), Gaps = 127/893 (14%)
Query: 221 EQRKKSDKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDD 280
E K+ ++N + R ++ L+ K +E +RL++ I L ++I++ D
Sbjct: 728 ELNKEVEENEALREEVILLS-----ELKSLPSEVERLRKEIQDKSEEL---HIITS-EKD 778
Query: 281 KKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKP 340
K S V +++S++ LL++ +G L + ++ E + D +K K
Sbjct: 779 KLFSEVVHKESRVQGLLEE-IGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVL 837
Query: 341 IVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVE--- 397
N + E+ +L ++ Q+ L G++ E S Q L EK + + E
Sbjct: 838 EEN-ERMNQEIVNLSKEAQKFDSSL---------GALKTELSYKTQELQEKTREVQERLN 887
Query: 398 ENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETL--E 455
E E+L L T Q +ER + EKL LEE++ K DL++L E+L E
Sbjct: 888 EMEQLKEQLENR-DSTLQTVERE--KTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIE 944
Query: 456 DQELKENVEIICNL-----QQLITQLSD-----ETVACTAAAIDTAVE-----EEAQVET 500
+LK ++ N+ +QL L ET+ + I V EE ET
Sbjct: 945 RDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGET 1004
Query: 501 SPETSRSSDAFTTQHALHQAQMSKEVVEL-NNALALKEALVRKMTQNDNQLQPIQFQYQD 559
E + + L ++ +N + ++ + + Q N+LQ +
Sbjct: 1005 KDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQM------ 1058
Query: 560 NIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQ 619
LE + ++ K +L ++ +N + +L K QE+ Q + + ++
Sbjct: 1059 ----LESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQ--EKNHAIKKE 1112
Query: 620 SKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERD 679
+L + + KL ++ ++ ++ QL+ +E +E QKK E+ LK
Sbjct: 1113 GELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEM-----QKKINEIENLKNEL 1167
Query: 680 RKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGI 739
+ ++ L +E + + L EE + K K + Q+ +R + + +E
Sbjct: 1168 KNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIE 1227
Query: 740 AARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCT 799
A L + E+ ++ K H + E R+ +++ Q+ ++ L K
Sbjct: 1228 A----TGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQD--------LEKSH 1275
Query: 800 FSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAES-----------ED 848
L E + E ++ + E ET+ + ++ Q D+ + +
Sbjct: 1276 TKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNE 1335
Query: 849 RPKQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKM------L 902
+ ++ E I ++ + + LK + L ++ +L+ +R++ A + Q +
Sbjct: 1336 KFQESQEEIKSLTKERDNLKTIKEAL---EVKHDQLKEHIRETLAKIQESQSKQEQSLNM 1392
Query: 903 FEEQNHFSEIETELQ------AELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKE 956
E+ N ++I +E++ + L+R+E + +L L +LQES K + K +
Sbjct: 1393 KEKDNETTKIVSEMEQFKPKDSALLRIEIE----MLGLSKRLQESHDEMKSVAKEKDDL- 1447
Query: 957 QQLVSTLQCQDEEL-EKMREVCEQNQQ-----------LLQENEIIKQKLILL-----QV 999
Q+L LQ + ++L E ++E+ ++ + L ++ E I + + L ++
Sbjct: 1448 QRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEI 1507
Query: 1000 ASRQKHLP--NDTLLSPDSSFEYIPPKPKPSRVKEKFLEQSMDIEDLKYCSEH 1050
++ QK L ND L + + I K + +K+ E + +LK EH
Sbjct: 1508 STIQKQLEAINDKL---QNKIQEIYEKEEQFNIKQ-ISEVQEKVNELKQFKEH 1556
Score = 60.8 bits (146), Expect = 8e-09
Identities = 125/665 (18%), Positives = 278/665 (41%), Gaps = 79/665 (11%)
Query: 382 SENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNE--KLNAKLEELRQ 439
SE L + L N KL + + Q+ I L + VNE K +++E+L++
Sbjct: 1798 SEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQL---ITLKKDVNETQKKVSEMEQLKK 1854
Query: 440 HVACK-LDLQKL-VETLE-DQELKENVEIICNLQQLITQLSDETVACTAAAIDTAVEEEA 496
+ + L L KL +E L Q+L EN+E + ++ + L +T E
Sbjct: 1855 QIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLR--------RVEETLKLERD 1906
Query: 497 QVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQ 556
Q++ S + +++ D Q +SKE E + L K+++ Q+ IQ
Sbjct: 1907 QLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLR------EKISEKTIQISDIQKD 1960
Query: 557 YQDNIKNLELEVINLQKEKEELVR---ELQTAKKNVNQA----KLSEHRHKLLQELEGQI 609
+ L+ ++ LQK++ +L+R ++ + K +N+ K E ++ +Q +
Sbjct: 1961 LDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDN 2020
Query: 610 ADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKD 669
L KKL+E + +++ + ++ + + M ++Q + +R+M + Q K +K
Sbjct: 2021 FQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEK- 2079
Query: 670 KEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTE--EAAAANKRLKDALQKQREVTDK 727
+ +Q+ L + +L+R +E + RL L+K+ E
Sbjct: 2080 ------RLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEF--- 2130
Query: 728 RKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKES 787
+KE K ++ E ++ + + + +++ K + V ++KE++
Sbjct: 2131 QKELSMRVKANLSLPYLQTKHIE-KLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHE 2189
Query: 788 RENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQ--------- 838
N F + + +E + + +I+ L+ + ++ S ++ DL+
Sbjct: 2190 SIN--------KFEMDFI--DEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHI 2239
Query: 839 QKLLDAESEDRPKQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADM 898
+++L SE +L + + + E ++++ + KL+N +++ +
Sbjct: 2240 EEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQV 2299
Query: 899 QKM-------LFEEQNHFSE----IETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQ 947
+ E F E I E + +L +++++ EK+ L+ S + Q
Sbjct: 2300 NNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKN-EKLFKNYQTLKTSLASGAQ 2358
Query: 948 LEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQQLLQENEIIKQ-KLILLQVASRQKHL 1006
+ + + + V T + EK+RE+ E + +E+ + K+ K+I +Q ++ +
Sbjct: 2359 VNPTTQDNKNPHV-TSRATQLTTEKIREL-ENSLHEAKESAMHKESKIIKMQ---KELEV 2413
Query: 1007 PNDTL 1011
ND +
Sbjct: 2414 TNDII 2418
Score = 54.3 bits (129), Expect = 7e-07
Identities = 158/791 (19%), Positives = 323/791 (40%), Gaps = 142/791 (17%)
Query: 280 DKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNK 339
DK V + KL+ + +D N+ L+E + L+ + K
Sbjct: 1791 DKLRGIVSEKTDKLSNMQKDLENSNA-------------KLQEKIQELKANEHQLITLKK 1837
Query: 340 PIVNIDPHTAELNHLKQQV--QQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSL-- 395
+ +E+ LK+Q+ Q L + L+ L ++ E E ++S+M++ +L
Sbjct: 1838 DVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLH-ENLEEMKSVMKERDNLRR 1896
Query: 396 VEENEKLSRCLSKAAGQ--------------TAQML--ERIILTEQVNEKLNAK---LEE 436
VEE KL R K + Q TA+ML E +++ EK++ K + +
Sbjct: 1897 VEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISD 1956
Query: 437 LRQHV-ACKLDLQKLVETLEDQEL-----KENVEI----ICNLQQLITQLSDETVACTAA 486
+++ + K +LQK ++ L+ +EL KE+V + I ++QL Q + ++ +
Sbjct: 1957 IQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSV 2016
Query: 487 AIDTAV-------------------EEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVV 527
+D +E +++ S + R T + + + + + +V
Sbjct: 2017 RMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVK 2076
Query: 528 ELNNALAL-KEALVRKMTQNDNQLQPIQFQYQDNIKNLE-LEVINLQKEKE-ELVRELQT 584
L+ ++ L + + ++++ + +Y + + E L ++L EKE E +EL
Sbjct: 2077 PEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSM 2136
Query: 585 -AKKNVNQAKL-SEHRHKLL---QELEGQIADLKKKLNEQ-SKLLKLKESTERTVSKLNQ 638
K N++ L ++H KL Q + + KKL S + K+KE +++K
Sbjct: 2137 RVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEM 2196
Query: 639 EIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQ-S 697
+ + + + KE K + +Q D +L++ LKL +N
Sbjct: 2197 DF-------IDEVEKQKELLIKIQHLQQDCDVPSRELRD---------LKLNQNMDLHIE 2240
Query: 698 SVLRRKTE-EAAAANKRLKDALQKQREVTDKRKETQSHG------KEGIA------ARVR 744
+L+ +E E + + L ++E+T +E + K GI +V
Sbjct: 2241 EILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVN 2300
Query: 745 NWLGNEIEVMV--STEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSL 802
N+ N I ++ STE +R E QD+ LKEK E L+ S
Sbjct: 2301 NFFNNRIIAIMNESTEFEERSATISKE----WEQDLKSLKEKNEKLFKNYQTLKTSLASG 2356
Query: 803 SEVHGQVLESEDC-ITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIATIL 861
++V+ ++++ +T + L TE +I +L+ L +A+ K+ + I+
Sbjct: 2357 AQVNPTTQDNKNPHVTSRATQLTTE------KIRELENSLHEAKESAMHKE-----SKII 2405
Query: 862 EAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELV 921
+ + L+ + + V + L ++K + +Q + + E +L+ +LV
Sbjct: 2406 KMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLV 2465
Query: 922 RMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQ 981
+++ + + K+ EK S + +T++ Q E + +RE ++Q
Sbjct: 2466 KIDLEKMKNA--------------KEFEKEISATK----ATVEYQKEVIRLLRENLRRSQ 2507
Query: 982 QLLQENEIIKQ 992
Q Q+ +I +
Sbjct: 2508 Q-AQDTSVISE 2517
Score = 44.7 bits (104), Expect = 6e-04
Identities = 74/450 (16%), Positives = 186/450 (41%), Gaps = 45/450 (10%)
Query: 382 SENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHV 441
+++++ L NQ E ++ + L ++ E E +N+ ++E+ +
Sbjct: 2149 TKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEE--QHESINKFEMDFIDEVEKQK 2206
Query: 442 ACKLDLQKL-----VETLEDQELKENVEIICNLQQLITQLSDETVACTAAAIDTAVEEEA 496
+ +Q L V + E ++LK N + ++++++ S+ +
Sbjct: 2207 ELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRK 2266
Query: 497 QVETSPETSRSSDAFTTQHALHQAQMSKE-VVELNNALALKE-ALVRKMTQNDNQLQPIQ 554
++ E ++ F + + Q + + ++NN + A++ + T+ + + I
Sbjct: 2267 EMTQFLEEWLNT-RFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATIS 2325
Query: 555 FQYQDNIKNLELEVINLQKEKEELVRELQ-------TAKKNVNQ---AKLSEHRHKLLQE 604
+++ ++K+L+ + L K + L L T + N N ++ ++ + ++E
Sbjct: 2326 KEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRE 2385
Query: 605 LEGQIADLKKK-LNEQSKLLKLKESTERT---VSKLNQEIWMMKNQRVQLMRQMKEDAEK 660
LE + + K+ ++++SK++K+++ E T ++KL ++ + ++ +K
Sbjct: 2386 LENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDK 2445
Query: 661 FRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQK 720
+ +E+ LK + K E +K + F+K+ S + E + L++ L++
Sbjct: 2446 VALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRR 2505
Query: 721 QREVTD------------KRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAK------- 761
++ D K G GI + + + + E +K
Sbjct: 2506 SQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQ 2565
Query: 762 --RHLNDLLEDRKILAQDVVQLKEKKESRE 789
+ N+LL + + L+ +V KE+ RE
Sbjct: 2566 LIKQKNELLSNNQHLSNEVKTWKERTLKRE 2595
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 309 bits (791), Expect = 1e-83
Identities = 308/1110 (27%), Positives = 522/1110 (47%), Gaps = 170/1110 (15%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVV------GTD-------KSFTYDFVFD 56
V+VA+R RP+ +E + + +T + GT K+FTYDF F
Sbjct: 4 VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFY 63
Query: 57 PC-------TEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENE 109
QE VF ++K F+GYNA V AYGQTGSGK+Y+M G N
Sbjct: 64 SADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMG-------NS 116
Query: 110 PTVGIIPRVIQLLFKEIDKKSDFE---FTLKVSYLEIYNEEILDLLCPSREKA-QINIRE 165
G+IPR+ + LF I++ + ++ F +VSYLEIYNE + DLL K + +RE
Sbjct: 117 GDSGLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVRE 176
Query: 166 DPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK- 224
PKEG + L++ V D ++ GN +RT A+T MN SSRSHAIFTI Q K
Sbjct: 177 HPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKF 236
Query: 225 KSDKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD----- 279
S+ C SK+HLVDLAGSER T A G RLKEG NIN+ L+ LGNVISAL D
Sbjct: 237 DSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDA 296
Query: 280 -----DKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRAR 334
KK FVPYRDS LT LL+DSLGGNS T+MIA +SPAD N ETLSTLRYA+RA+
Sbjct: 297 ANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAK 356
Query: 335 KIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQS 394
I NKP +N D + + L+ ++ +L+ LL Q G +++ + +++ +++N++
Sbjct: 357 NIINKPTINEDANVKLIRELRAEIARLKTLLAQ---GNQIALLDSPTALSMEEKLQQNEA 413
Query: 395 LVEENEKLSRCLSKAAGQTAQMLERIILT---EQVNEKLNAKLEEL----RQHVACKLDL 447
V+E L++ + +T +L+ L E + L+++L L ++ + L
Sbjct: 414 RVQE---LTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIIL 470
Query: 448 QKLVE----------------TLEDQELKENVEIICNLQQLITQLSDETVACTAAAID-- 489
L E L +L+ I N+ +T + C+ +
Sbjct: 471 YHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIV 530
Query: 490 --TAVEEEAQV--------------ETSPETSRSSDAFTTQHALHQAQMSKEVVELNNAL 533
T + + A + E + + + +L +SK L+ +
Sbjct: 531 EATHLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVM 590
Query: 534 ALKEALVRKMTQNDNQLQPIQF------QYQDNIKNLELEVINLQKE-----KEELVREL 582
L + Q + +L+ ++ + ++ K+ + E+ +Q+E KE + +L
Sbjct: 591 LYNPGLEFERQQRE-ELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQL 649
Query: 583 QTAKKNVNQAKLSEHRHKLLQEL-------------EGQIADLKKKLNEQSKLLKLKEST 629
Q K+ + + S H L++L E Q +L+KK E+ L+++E
Sbjct: 650 QIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEEL 709
Query: 630 ERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKL 689
+R N E K ++ Q+ +++ + ++ + K + E +L+E+++++ + L
Sbjct: 710 QRLKELNNNE----KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHL 765
Query: 690 E---RNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNW 746
E R Q+ +LRR + KR L+ RE + KE ++ G E
Sbjct: 766 EEQLREKQEMIQLLRRGEVQWVEEEKR---DLEGIRESLLRVKEARAGGDED-------- 814
Query: 747 LGNEIE--VMVSTEEAKRHLNDLLEDRKILAQDVVQLKE--KKESRENPPPKLRKCTFSL 802
G E+E + E +R L L+ L +D+VQ K+ KKE +E ++ +C
Sbjct: 815 -GEELEKAQLRFFEFKRRQLVKLVN----LEKDLVQQKDILKKEVQEE--QEILECLKCE 867
Query: 803 SEVHGQVLESED-CIT---------KQIESLETEMELRSAQIADLQQKLLDAESEDRPKQ 852
+ ++LE D +T ++I+ +E ++ + Q+ L Q L E++ ++
Sbjct: 868 HDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEK-QR 926
Query: 853 CWENI--------ATILEAKCALKYLIGELVSSKIHVTKLE--NSLRQSKASCADMQKML 902
+E + T+ + + ++ +L + + +L+ + + A+ A ++ +
Sbjct: 927 AFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKV 986
Query: 903 FEEQNHFSEIETELQAE-----LVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQ 957
+++ E + Q E L R+E++H + ++ + +K ++ +EQ
Sbjct: 987 RKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQ 1046
Query: 958 Q-LVSTLQCQDEELEKMREVCEQNQQLLQE 986
L ++L+ + E LEK +E E Q L++
Sbjct: 1047 SGLQASLEAEQEALEKDQERLEYEIQQLKQ 1076
Score = 69.3 bits (168), Expect = 2e-11
Identities = 110/505 (21%), Positives = 226/505 (44%), Gaps = 76/505 (15%)
Query: 519 QAQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEEL 578
+ Q +E+ +L + L E + K + +L+ +Q + + K E+ + ++K++E L
Sbjct: 599 ERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESL 658
Query: 579 VRE---LQTAKKNV--NQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTV 633
R ++ K++ + K E R + QE+E L+KK E+ L+++E +R
Sbjct: 659 KRRSFHIENKLKDLLAEKEKFEEERLREQQEIE-----LQKKRQEEETFLRVQEELQRLK 713
Query: 634 SKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLE--- 690
N E K ++ Q+ +++ + ++ + K + E +L+E+++++ + LE
Sbjct: 714 ELNNNE----KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQL 769
Query: 691 RNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNE 750
R Q+ +LRR + KR L+ RE + KE ++ G E G E
Sbjct: 770 REKQEMIQLLRRGEVQWVEEEKR---DLEGIRESLLRVKEARAGGDED---------GEE 817
Query: 751 IEV--MVSTEEAKRHLNDLLEDRKILAQDVVQLKE--KKESRENPPPKLRKCTFSLSEVH 806
+E + E +R L L+ L +D+VQ K+ KKE +E ++ +C +
Sbjct: 818 LEKAQLRFFEFKRRQLVKLVN----LEKDLVQQKDILKKEVQEEQ--EILECLKCEHDKE 871
Query: 807 GQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQ--CWENIATILEAK 864
++LE D + + + E +I ++ +L + ++R Q ++ T+LE K
Sbjct: 872 SRLLEKHDESVTDVTEVPQDFE----KIKPVEYRL---QYKERQLQYLLQNHLPTLLEEK 924
Query: 865 CALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIET-----ELQAE 919
++ S L+N+L Q + + ++ L + Q + ++++ E A
Sbjct: 925 QRAFEILDRGPLS------LDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTAN 978
Query: 920 LVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQ 979
+ R E++ ++K EK++ +S +E+Q L+ LE+ ++
Sbjct: 979 IARQEEKVRKK--------------EKEILES---REKQQREALERALARLERRHSALQR 1021
Query: 980 NQQLLQENEIIKQKLILLQVASRQK 1004
+ L E E +QKL L SR++
Sbjct: 1022 HSTLGMEIEEQRQKLASLNSGSREQ 1046
Score = 51.2 bits (121), Expect = 6e-06
Identities = 82/410 (20%), Positives = 180/410 (43%), Gaps = 64/410 (15%)
Query: 629 TERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLK 688
T+ + S+ N M+ N ++ RQ +E+ EK + K K + +++E+ + + EL +
Sbjct: 577 TDLSKSRENLSAVMLYNPGLEFERQQREELEKL----ESKRKLIEEMEEKQKSDKAELER 632
Query: 689 LERNFQKQSSVLRRKTEEAAAANKRLKDALQKQR-EVTDKRKETQSHGKEGIAARVRNWL 747
+++ + Q R++TE ++ +++L+++ + +K K+ + ++ R+R
Sbjct: 633 MQQEVETQ----RKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQ- 687
Query: 748 GNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHG 807
EIE+ +E + L + +++ +LKE + K K
Sbjct: 688 -QEIELQKKRQEEETFLR--------VQEELQRLKELNNNE-----KAEKF--------- 724
Query: 808 QVLESEDCITKQIESLETEMELRSAQIADLQ--QKLLDAESEDRPKQCWENIATILEAKC 865
Q+ + D + K+ + ++EL ++ + + Q +L A E++ ++ E I + +
Sbjct: 725 QIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGE- 783
Query: 866 ALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQ 925
+ + K + + SL + K E + E EL+ +R +
Sbjct: 784 -----VQWVEEEKRDLEGIRESLLRVK-----------EARAGGDEDGEELEKAQLRFFE 827
Query: 926 QHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEE----LEKMREVCEQNQ 981
+ +++ LV+ L++ + +K + K ++EQ+++ L+C+ ++ LEK E
Sbjct: 828 FKRRQLVKLVN-LEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVT 886
Query: 982 QLLQENEIIKQKLILLQVASR------QKHLPNDTLLSPDSSFEYIPPKP 1025
++ Q+ E IK LQ R Q HLP L +FE + P
Sbjct: 887 EVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPT-LLEEKQRAFEILDRGP 935
Score = 44.7 bits (104), Expect = 6e-04
Identities = 87/488 (17%), Positives = 206/488 (42%), Gaps = 70/488 (14%)
Query: 397 EENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLED 456
EE ++L + + Q+ + + ++ ++ AKLE ++ + + Q ++ +
Sbjct: 707 EELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLE 766
Query: 457 QELKENVEIICNLQQLITQLSDETVACTAAAIDTAVE-EEAQVETSPETSRSSDAFTTQH 515
++L+E E+I L++ Q +E ++ + +EA+ + A
Sbjct: 767 EQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFF 826
Query: 516 ALHQAQMSKEVVELNNALALKEALVRKMTQNDNQ-LQPIQFQYQDNIKNLELEVINLQKE 574
+ Q+ K +V L L ++ +++K Q + + L+ ++ ++ + LE +
Sbjct: 827 EFKRRQLVK-LVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLE--------K 877
Query: 575 KEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVS 634
+E V ++ ++ + K E+R LQ E Q+ L Q+ L L E +R
Sbjct: 878 HDESVTDVTEVPQDFEKIKPVEYR---LQYKERQLQYLL-----QNHLPTLLEEKQRAFE 929
Query: 635 KLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDK------------EVIQLKERDRKR 682
L++ + N Q+ ++M+E E+ Q++ ++ + + +E+ RK+
Sbjct: 930 ILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKK 989
Query: 683 QYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQ----REVTDKRKETQSHGKEG 738
+ E+L+ Q+++ E A A +R ALQ+ E+ ++R++ S
Sbjct: 990 EKEILESREKQQREA------LERALARLERRHSALQRHSTLGMEIEEQRQKLASLNS-- 1041
Query: 739 IAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKC 798
+R ++ L +E + +EA L +D++ L ++ QLK+K
Sbjct: 1042 -GSREQSGLQASLE---AEQEA------LEKDQERLEYEIQQLKQK-------------- 1077
Query: 799 TFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIA 858
+ EV G + + ++ S + + + L ++A E+ ++ +++
Sbjct: 1078 ---IYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLH 1134
Query: 859 TILEAKCA 866
++ C+
Sbjct: 1135 RVISEGCS 1142
Score = 36.2 bits (82), Expect = 0.20
Identities = 53/254 (20%), Positives = 104/254 (40%), Gaps = 33/254 (12%)
Query: 805 VHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIATILEAK 864
+HG LESE CI + I T + L +Q + ++++A ++ A IL +
Sbjct: 493 LHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQG-------AVILLGR 545
Query: 865 CALKYLIGELVSSKIHVTKLENSLRQSKASCADMQK--------MLFEEQNHFSEIETEL 916
+ ++K+ + L S D+ K ML+ N E E +
Sbjct: 546 TNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLY---NPGLEFERQQ 602
Query: 917 QAELVRMEQQHQEKVLYLVSQLQESQMAEK------QLEKSASEKEQQLVSTLQCQDEEL 970
+ EL ++E + + L+ +++E Q ++K Q E KE ++V + EE
Sbjct: 603 REELEKLESKRK-----LIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEES 657
Query: 971 EKMREVCEQN--QQLLQENEIIKQKLILLQ--VASRQKHLPNDTLLSPDSSFEYIPPKPK 1026
K R +N + LL E E +++ + Q + ++K +T L + +
Sbjct: 658 LKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNN 717
Query: 1027 PSRVKEKFLEQSMD 1040
+ ++ + Q +D
Sbjct: 718 NEKAEKFQIFQELD 731
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 305 bits (782), Expect = 1e-82
Identities = 169/346 (48%), Positives = 220/346 (63%), Gaps = 9/346 (2%)
Query: 9 PVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKA 68
PVRVALR RPL+PKE+ G Q CL PG +V +G D+ F + V QE V+
Sbjct: 15 PVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQAC 74
Query: 69 VAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEIDK 128
V PL++ F+G+NATV AYGQTGSGKTY+MG A A E GI+PR + FK ID+
Sbjct: 75 VQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASL-LEDEQGIVPRAMAEAFKLIDE 133
Query: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
+ + VSYLE+Y EE DLL I +RED + + + G+ E V + +
Sbjct: 134 NDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVEGLDEVL 193
Query: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCS-------FRSKLHLVDL 241
S LE GN +R +T +N SSRSH +FT+++EQR ++ SK H VDL
Sbjct: 194 SLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSKFHFVDL 253
Query: 242 AGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD-DKKGSFVPYRDSKLTRLLQDS 300
AGSER KT + G+RLKE I IN LL LGNVISALGD ++GS +PYRDSK+TR+L+DS
Sbjct: 254 AGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDS 313
Query: 301 LGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDP 346
LGGN+ T+MIACVSP+ S+ +ETL+TL YA RA+ I+N+ VN P
Sbjct: 314 LGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRP 359
Score = 111 bits (278), Expect = 4e-24
Identities = 122/528 (23%), Positives = 244/528 (46%), Gaps = 75/528 (14%)
Query: 520 AQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELV 579
AQ +++ EL + +KE L+ ++ + Q + Q+ I+ LE E ++ E E
Sbjct: 704 AQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQ 763
Query: 580 RELQTAKKNVNQ-----AKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVS 634
R+L+ + Q ++L E R ++ + Q+ LK+K +L+ L +E+ +
Sbjct: 764 RQLRELEGKELQDAGERSRLQEFRRRVAAA-QSQVQVLKEKKQATERLVSLSAQSEKRLQ 822
Query: 635 KLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQ 694
+L + + +M+ Q+ QL R+++E+ E+ R+ L+ KRQ+ + +LE +
Sbjct: 823 ELERNVQLMRQQQGQLQRRLREETEQKRR-----------LEAEMSKRQHRVKELELKHE 871
Query: 695 KQSSVLRRKTEEAAAANKRLKD-------ALQKQREVTDKRKETQSHGKEGI-AARVRNW 746
+Q +L+ KTEE AA ++ + +L++Q+++ +++K ++ + R
Sbjct: 872 QQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEE 931
Query: 747 LGNEI---EVMVSTEEAKRHLNDLLEDRKI-----LAQDVVQLKEKKESRENPPPKLRKC 798
LG E+ E +++ +EA LE +++ L +D+V++ + E E
Sbjct: 932 LGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEK-------- 983
Query: 799 TFSLSEVHGQV----LESEDCITKQIESLETEMELRSAQIADLQQKL----LDAESEDRP 850
LSE GQ+ +S+ I +I+SL E + Q ++ KL L + E+R
Sbjct: 984 --ELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEER- 1040
Query: 851 KQCWENIATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFS 910
T+ + A++ L + +T + LR S + + + L + ++ S
Sbjct: 1041 --------TLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLS 1092
Query: 911 EIETE------LQAELVRMEQQHQEKVLY--LVSQLQESQ----MAEKQLEKSASEKEQQ 958
ET + E+QHQ+++ + L QL+E Q E LE+ E ++Q
Sbjct: 1093 SSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQ 1152
Query: 959 LVSTLQCQDEELEKMREVCEQNQQLLQENEIIKQKLILLQVASRQKHL 1006
L TLQ Q E + M+ + +Q++ L E ++ ++ + +K L
Sbjct: 1153 L--TLQ-QKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKEL 1197
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 304 bits (779), Expect = 3e-82
Identities = 319/1082 (29%), Positives = 507/1082 (46%), Gaps = 185/1082 (17%)
Query: 6 KGIPVRVALRCRPLVPKEIS-EGCQ-MCLSFVPGETQVVVGTD---KSFTYDFVFDPCTE 60
+G ++V +R RP + S +G Q +CLS V T + + ++ K+FT+D V D T
Sbjct: 23 EGDAIKVFVRIRPPAERSGSADGEQNLCLS-VLSSTSLRLHSNPEPKTFTFDHVADVDTT 81
Query: 61 QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQ 120
QE VF +++ GYN T+ AYGQTGSGKT++M G ++ + G+IPR +
Sbjct: 82 QESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIPRSFE 141
Query: 121 LLFKEIDKKSD-----FEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVG 175
LF ID++ + F K S++EIYNE+I DLL A + +RE K+G+ +VG
Sbjct: 142 YLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLL--DSASAGLYLREHIKKGVFVVG 199
Query: 176 LTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFR-S 234
E+ V A + L G +R VAST+MN +SSRSHA+FTI+IE +KS++ + R S
Sbjct: 200 AVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEKSNEIVNIRTS 259
Query: 235 KLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD--DKKGSFVPYRDSK 292
L+LVDLAGSERQK T AEG RLKE NINR L CLG VI+AL D + K V YRDSK
Sbjct: 260 LLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNGKQRHVCYRDSK 319
Query: 293 LTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPH----- 347
LT LL+DSLGGN+ T +IA V P ETLSTL +A RA+ IKNK +VN D
Sbjct: 320 LTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNEDTQGNVSQ 379
Query: 348 -TAELNHLKQQVQQLQVLLLQAHGGTLPGSI------NAEPSENLQSLM-------EKNQ 393
AE+ LK+Q+ +L A G T P S E Q M ++ +
Sbjct: 380 LQAEVKRLKEQLAEL------ASGQTPPESFLTRDKKKTNYMEYFQEAMLFFKKSEQEKK 433
Query: 394 SLVEENEKLSRCLSKAAG--QTAQML-----ERIILTEQVN---------EKLNAKLEEL 437
SL+E+ +L K Q+ +M+ ++II E+++ E+ + L EL
Sbjct: 434 SLIEKVTQLEDLTLKKEKFIQSNKMIVKFREDQIIRLEKLHKESRGGFLPEEQDRLLSEL 493
Query: 438 RQHVACKLDLQKLVE--------TLEDQELKENVEIICNLQQLITQLSDETVACTAAAID 489
R + L++ +E +E+ L+E + L+ + + + E A T A ++
Sbjct: 494 RNEIQ---TLREQIEHHPRVAKYAMENHSLREENRRLRLLEPV--KRAQEMDAQTIAKLE 548
Query: 490 TAVEEEAQVET--------SPETSRSSDAFTTQHALHQAQMSKEVVELNNAL----ALKE 537
A E + +E SP+ + F L +AQ+ + ELNN+ KE
Sbjct: 549 KAFSEISGMEKSDKNQQGFSPKAQKEPCLFANTEKL-KAQLLQIQTELNNSKQEYEEFKE 607
Query: 538 ALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVREL-----QTAKKNVNQA 592
++ + +++LQ +Q + N++NL LE K +E V +L +T K
Sbjct: 608 LTRKRQLELESELQSLQ-KANLNLENL-LEATKACKRQE--VSQLNKIHAETLKIITTPT 663
Query: 593 KLSEHRHKLLQELEGQIADLKKKLNEQSKLLK--------LKESTERTVSKLNQEIWMMK 644
K + + + +L ++ + S +L E E+ +++E+ ++
Sbjct: 664 KAYQLHSRPVPKLSPEMGSFGSLYTQNSSILDNDILNEPVPPEMNEQAFEAISEELRTVQ 723
Query: 645 NQRVQLMRQMKEDAEKFRQWKQKKDK---EVIQLKERDRKRQYELLKLERNFQKQSSVLR 701
Q L ++ E+ K + +Q DK Q++E + + K + Q +VL
Sbjct: 724 EQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLE 783
Query: 702 RKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAK 761
++ +E N LK EV D R S KE + + +E +
Sbjct: 784 KQLQETQTKNDFLKS------EVHDLRVVLHSADKELSSVK--------LEYSSFKTNQE 829
Query: 762 RHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIE 821
+ N L E + + L+ + E ++LES+ C+ +
Sbjct: 830 KEFNKLSERHMHVQLQLDNLRLENE---------------------KLLESKACLQDSYD 868
Query: 822 SLETEMELRSAQIADLQQKLLDAESEDRP-KQCWENIATILEAKCALKYLIGELVSSKIH 880
+L+ E+ +I L + L + + E+ K N+ +LEA+
Sbjct: 869 NLQ---EIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAE---------------- 909
Query: 881 VTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQ----EKVLYLVS 936
R +K S + FEE S E E VR E+Q + E+ + V
Sbjct: 910 ------KERNNKLS------LQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQ 957
Query: 937 QLQESQMAEKQ----LEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQQLLQENEIIKQ 992
+L+ES +A ++ LEKS + ++++V+ L Q +EL VCE+ + + + +KQ
Sbjct: 958 KLEESLLATEKVISSLEKS-RDSDKKVVADLMNQIQELR--TSVCEKTETI----DTLKQ 1010
Query: 993 KL 994
+L
Sbjct: 1011 EL 1012
Score = 65.1 bits (157), Expect = 4e-10
Identities = 138/731 (18%), Positives = 301/731 (41%), Gaps = 85/731 (11%)
Query: 350 ELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKA 409
ELN+ KQ+ ++ + L + E LQSL + N +L E C +
Sbjct: 594 ELNNSKQEYEEFKELTRKRQ---------LELESELQSLQKANLNLENLLEATKACKRQE 644
Query: 410 AGQT----AQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEI 465
Q A+ L+ I + + + + +L + L ++ D ++
Sbjct: 645 VSQLNKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSILDNDILN---- 700
Query: 466 ICNLQQLITQLSDETVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKE 525
+ + +++++ + + T E+ + ++ + + QH S +
Sbjct: 701 ----EPVPPEMNEQAFEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQ 756
Query: 526 VVELNNALAL-----KEALVRKMTQNDNQLQPIQFQ---YQDNIKNLELEVINLQKEKEE 577
+ EL ++ + +E L+ ++ + QLQ Q + + + +L + + + KE
Sbjct: 757 MQELFSSERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSS 816
Query: 578 LVRELQTAKKNVNQA--KLSE-HRHKLLQ----ELEGQIADLKKKLNEQSKLLKLKESTE 630
+ E + K N + KLSE H H LQ LE + L+ K Q L+E +
Sbjct: 817 VKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKL-LESKACLQDSYDNLQEIMK 875
Query: 631 RTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLE 690
+ +L++ + K + L + E K++ +K +Q +E E+LK+
Sbjct: 876 FEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVL 935
Query: 691 RNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNE 750
+++ K E+ A ++L+++L +V ++++ K+ +A L N+
Sbjct: 936 EAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVAD-----LMNQ 990
Query: 751 I-EVMVSTEEAKRHLNDLLEDRK-ILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQ 808
I E+ S E ++ L ++ K I + L +++ESR + +
Sbjct: 991 IQELRTSVCEKTETIDTLKQELKDINCKYNSALVDREESR-----------VLIKKQEVD 1039
Query: 809 VLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIATILEAKCA-- 866
+L+ ++ + +I S + E ++ +A ++L N+ T K +
Sbjct: 1040 ILDLKETLRLRILSEDIERDMLCEDLAHATEQL--------------NMLTEASKKHSGL 1085
Query: 867 LKYLIGELVSSKIHVTKLENSLRQSKASCADMQ-----KMLFEEQNHFSEIETELQAELV 921
L+ EL + + +L++ L Q K + KM E S E +
Sbjct: 1086 LQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTP 1145
Query: 922 RMEQQHQEKVLYLVSQ-LQESQMAEKQLE----KSASEKEQQLVSTLQCQDEELEKMREV 976
Q H K+L Q +++ + ++ LE K ++E + L+ + E+L +M +
Sbjct: 1146 PHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMK-EQLREMENL 1204
Query: 977 CEQNQQLLQENEIIKQKL--ILLQVASRQKHLPNDTLLSPDSSFEYIPPKPKPSRVKEKF 1034
++QQL+++N +++ +L I Q + ++ P++ L + E I + S++ E+
Sbjct: 1205 RLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQE-ESIKERLAKSKIVEEM 1263
Query: 1035 LEQSMDIEDLK 1045
L+ D+E+++
Sbjct: 1264 LKMKADLEEVQ 1274
Score = 59.7 bits (143), Expect = 2e-08
Identities = 103/540 (19%), Positives = 220/540 (40%), Gaps = 64/540 (11%)
Query: 311 ACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHG 370
AC+ + NL+E + +R ++N N + ++LN+L + ++ +
Sbjct: 861 ACLQDSYDNLQEIMK-FEIDQLSRNLQNFKKEN-ETLKSDLNNLMELLEAEK-----ERN 913
Query: 371 GTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNEKL 430
L + + + +++ +++ +E +K + + + ++ E ++ TE+V L
Sbjct: 914 NKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSL 973
Query: 431 NA--------------KLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQL 476
+++ELR V K + ++TL+ QELK+ I C +
Sbjct: 974 EKSRDSDKKVVADLMNQIQELRTSVCEKTET---IDTLK-QELKD---INCKYNSALVDR 1026
Query: 477 SDETVACTAAAIDTA-VEEEAQVET-SPETSRSSDAFTTQHALHQAQMSKEVVELNNALA 534
+ V +D ++E ++ S + R HA Q M E + ++ L
Sbjct: 1027 EESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLL 1086
Query: 535 LKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAK- 593
++ ++T+ + +Q +Q + + +E + + +L + +A ++ K
Sbjct: 1087 --QSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKT 1144
Query: 594 ---LSEHRHKLLQELEGQIAD----------LKKKLNEQ-----SKLLKLKESTERTVS- 634
H KLL+ E +I D L KLNE +++L++KE +
Sbjct: 1145 PPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENL 1204
Query: 635 -----KLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQY--ELL 687
+L ++ W+++ Q + RQ + + +Q K+++ +KER K + E+L
Sbjct: 1205 RLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEML 1264
Query: 688 KLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWL 747
K++ + ++ S L K E ++ + + ++++ +S +E R R
Sbjct: 1265 KMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERT-- 1322
Query: 748 GNEIEVMVSTEEAKRHLNDLLEDRKILAQD---VVQLKEKKESRENPPPKLRKCTFSLSE 804
E+E++ E N L + L Q VV+LK++ KLR L E
Sbjct: 1323 SQEMEMLRKQVECLAEENGKLVGHQNLHQKIQYVVRLKKENVRLAEETEKLRAENVFLKE 1382
Score = 41.6 bits (96), Expect = 0.005
Identities = 104/554 (18%), Positives = 221/554 (39%), Gaps = 83/554 (14%)
Query: 105 EQENEPTVGIIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIR 164
++ENE + +++LL E ++ + + E ++EIL +L R++ Q
Sbjct: 889 KKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDK-ENSSKEILKVLEAVRQEKQKETA 947
Query: 165 EDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNS-RTVASTAMNS----QSSRSHAIFTIS 219
+ ++ K+ L E+++L +S LE+ +S + V + MN ++S TI
Sbjct: 948 KCEQQMAKVQKL-EESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETID 1006
Query: 220 IEQRKKSDKNCSFRSKLHLVDLAGSERQ-KKTKAEGDRLKEGININRGLLCLGNVISALG 278
+++ D NC + S L VD S KK + + LKE + +
Sbjct: 1007 TLKQELKDINCKYNSAL--VDREESRVLIKKQEVDILDLKETLRLR-------------- 1050
Query: 279 DDKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKN 338
+ D + L +D M+ S S L ++ A++
Sbjct: 1051 -------ILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQS---------AQEELT 1094
Query: 339 KPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEE 398
K I +LN K++V+Q + E + ++ L S E+
Sbjct: 1095 KKEALIQELQHKLNQKKEEVEQKK----------------NEYNFKMRQLEHVMDSAAED 1138
Query: 399 NEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQE 458
+ K L +++ T++ + + +H+ KL+ + V+ E
Sbjct: 1139 PQS-----PKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILR 1193
Query: 459 LKENVEIICNLQQLITQLSDETVACTAAAIDTAVEEEAQVETSPETS--RSSDAFTTQHA 516
+KE + + NL+ QL ++ D ++E + P+ ++ + +
Sbjct: 1194 MKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKER 1253
Query: 517 LHQAQMSKEVV-------ELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVI 569
L ++++ +E++ E+ +AL KE +MT + Q ++ + + L ++
Sbjct: 1254 LAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLE 1313
Query: 570 NLQKEKEELVRELQTAKKNV-----NQAKLSEHR--HKLLQEL------EGQIADLKKKL 616
+ +E+E +E++ +K V KL H+ H+ +Q + ++A+ +KL
Sbjct: 1314 EMYEERERTSQEMEMLRKQVECLAEENGKLVGHQNLHQKIQYVVRLKKENVRLAEETEKL 1373
Query: 617 NEQSKLLKLKESTE 630
++ LK K+ +E
Sbjct: 1374 RAENVFLKEKKRSE 1387
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 301 bits (770), Expect = 3e-81
Identities = 240/710 (33%), Positives = 357/710 (50%), Gaps = 83/710 (11%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVG-TD------KSFTYDFVFDPCTEQE 62
V+V +RCRPL +E S + +S + V TD K+FT+D VF P ++Q
Sbjct: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
Query: 63 EVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLL 122
+V+N P+I + +GYN T+ AYGQTG+GKT++M G + GIIP +
Sbjct: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELR----GIIPNSFAHI 130
Query: 123 FKEIDK-KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTV 181
F I K + D F ++VSYLEIYNEE+ DLL + + ++ ++E P G+ I L+ V
Sbjct: 131 FGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQ-RLEVKERPDVGVYIKDLSAYVV 189
Query: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKS-DKNCSFR-SKLHLV 239
A D + G+ +R+V +T MN SSRSHAIFTI+IE +K D N R KLHLV
Sbjct: 190 NNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLV 249
Query: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQD 299
DLAGSERQ KT A G RLKE IN L LGNVISAL D K + VPYR+SKLTRLLQD
Sbjct: 250 DLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKS-THVPYRNSKLTRLLQD 308
Query: 300 SLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQ 359
SLGGNS T+M A + PAD N +ET+STLRYA+RA+ IKNK +N DP A L +++++
Sbjct: 309 SLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIE 368
Query: 360 QLQVLLLQAH---GGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQM 416
+L+ L + G + GS + E + E+ EK + K +M
Sbjct: 369 ELKKKLEEGEEISGSDISGSEEDDDEEG---------EVGEDGEKRKKRRGKKKVSPDKM 419
Query: 417 LERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQL 476
+E + AK++E R+ + KLD+++ EL++ + + QQ L
Sbjct: 420 IE-----------MQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSL 468
Query: 477 SDETVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALK 536
++ A I V+ A+ E + S+ +EL
Sbjct: 469 LEKLSALEKKVIVGGVDLLAKAEEQEKLLEESN-----------------MELEERRKRA 511
Query: 537 EALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSE 596
E L R++ + + + I+ +Y +L+ E K+ +++ L AK + A L +
Sbjct: 512 EQLRRELEEKEQERLDIEEKY----TSLQEEAQGKTKKLKKVWTMLMAAKSEM--ADLQQ 565
Query: 597 HRHKLLQELEGQIADLKKKLNEQSKLL------KLKESTERTVSKLNQEI--WMMK---- 644
+ ++ L I L ++L Q ++ +E E V N++I W +K
Sbjct: 566 EHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYV-HWNEDIGEWQLKCVAY 624
Query: 645 ---NQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLER 691
N R Q K++ + F + D + L + + L+KLER
Sbjct: 625 TGNNMRKQTPVPDKKEKDPF-----EVDLSHVYLAYTEESLRQSLMKLER 669
Score = 47.8 bits (112), Expect = 7e-05
Identities = 59/266 (22%), Positives = 111/266 (41%), Gaps = 39/266 (14%)
Query: 579 VRELQTAKKNVNQAKLSEH-RHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLN 637
+R AK N+A+++E + LL++ + +I +LKKKL E ++ S
Sbjct: 336 LRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEE 395
Query: 638 QEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQS 697
E+ ED EK ++ + KK ++ E K E LE +
Sbjct: 396 GEVG--------------EDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEE 441
Query: 698 SVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVST 757
+ + A KR KD L+ Q+E ++ + K+ I V +++
Sbjct: 442 E---ERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGV--------DLLAKA 490
Query: 758 EEAKRHLNDL---LEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESED 814
EE ++ L + LE+R+ A+ + + E+KE + E + + E
Sbjct: 491 EEQEKLLEESNMELEERRKRAEQLRRELEEKEQER----------LDIEEKYTSLQEEAQ 540
Query: 815 CITKQIESLETEMELRSAQIADLQQK 840
TK+++ + T + +++ADLQQ+
Sbjct: 541 GKTKKLKKVWTMLMAAKSEMADLQQE 566
Score = 41.2 bits (95), Expect = 0.006
Identities = 59/272 (21%), Positives = 121/272 (44%), Gaps = 35/272 (12%)
Query: 567 EVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLK 626
++I +Q + +E + L+T K ++ + E R+K ELE + DL K E LL+
Sbjct: 418 KMIEMQAKIDEERKALET-KLDMEE----EERNKARAELEKREKDLLKAQQEHQSLLEKL 472
Query: 627 ESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYEL 686
+ E+ V ++ ++ +L+ + + E+ R K QL+ +++ E
Sbjct: 473 SALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERR-------KRAEQLRRELEEKEQER 525
Query: 687 LKLERNFQKQSSVLRRKTEEAAAANKRLKDA----LQKQREVTDKRKETQSHGKEGIAAR 742
L +E +K +S+ EEA K+LK + + E+ D ++E Q EG+
Sbjct: 526 LDIE---EKYTSL----QEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQRE-IEGLLEN 577
Query: 743 VRNWLGNE--IEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEK-------KESRENP-P 792
+R L E +++++ R +++E+ +D+ + + K ++ P P
Sbjct: 578 IRQ-LSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVP 636
Query: 793 PKLRKCTFSLSEVHGQVLESEDCITKQIESLE 824
K K F + H + +E+ + + + LE
Sbjct: 637 DKKEKDPFEVDLSHVYLAYTEESLRQSLMKLE 668
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 296 bits (759), Expect = 6e-80
Identities = 191/533 (35%), Positives = 296/533 (55%), Gaps = 30/533 (5%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTD-------KSFTYDFVFDPCTEQE 62
V+V +RCRP+ +E CQ ++ Q + K FT+D + E
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 63 EVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLL 122
+++N+ PL++G+ +GYN T+ AYGQTGSGK+++M G + GIIPR + +
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQR----GIIPRAFEHV 121
Query: 123 FKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVL 182
F+ + + +F ++ SYLEIYNE++ DLL + K ++ ++E P++G+ + GL+ TV
Sbjct: 122 FESVQCAENTKFLVRASYLEIYNEDVRDLL-GADTKQKLELKEHPEKGVYVKGLSMHTVH 180
Query: 183 VALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSF--RSKLHLVD 240
+E G +R+V T MN SSRSH+IFTISIE ++ KL+LVD
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVD 240
Query: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDS 300
LAGSERQ KT A G+RLKE IN L LGNVISAL D + VPYRDSKLTRLLQDS
Sbjct: 241 LAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRC-KHVPYRDSKLTRLLQDS 299
Query: 301 LGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQ 360
LGGN+ TLM+AC+SPAD+N +ETLSTLRYA+RA+ I+NKP +N DP A L ++++++
Sbjct: 300 LGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKK 359
Query: 361 LQVLLLQ-----AHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQ 415
L+ +L Q + L + +P + + L+ Q +++ + + + L + + +
Sbjct: 360 LKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLP--QPVIQHDVEAEKQLIRE--EYEE 415
Query: 416 MLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQ 475
L R+ + ++ A+LEE A + + TLE+ KE ++ +
Sbjct: 416 RLARLKADYKAEQESRARLEE--DITAMRNSYDVRLSTLEENLRKETEAVLQVGVLYKAE 473
Query: 476 LSDETVACTAAAIDTAVEEEAQVE----TSPETSRSSDAFTTQHALHQAQMSK 524
+ ++A A + E V+ ++ +T S D TQ + A++ K
Sbjct: 474 VMSRAEFASSAEYPPAFQYETVVKPKVFSTTDTLPSDDVSKTQVSSRFAELPK 526
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 296 bits (759), Expect = 6e-80
Identities = 191/533 (35%), Positives = 296/533 (55%), Gaps = 30/533 (5%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTD-------KSFTYDFVFDPCTEQE 62
V+V +RCRP+ +E CQ ++ Q + K FT+D + E
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 63 EVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLL 122
+++N+ PL++G+ +GYN T+ AYGQTGSGK+++M G + GIIPR + +
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQR----GIIPRAFEHV 121
Query: 123 FKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVL 182
F+ + + +F ++ SYLEIYNE++ DLL + K ++ ++E P++G+ + GL+ TV
Sbjct: 122 FESVQCAENTKFLVRASYLEIYNEDVRDLL-GADTKQKLELKEHPEKGVYVKGLSMHTVH 180
Query: 183 VALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSF--RSKLHLVD 240
+E G +R+V T MN SSRSH+IFTISIE ++ KL+LVD
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVD 240
Query: 241 LAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDS 300
LAGSERQ KT A G+RLKE IN L LGNVISAL D + VPYRDSKLTRLLQDS
Sbjct: 241 LAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRC-KHVPYRDSKLTRLLQDS 299
Query: 301 LGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQ 360
LGGN+ TLM+AC+SPAD+N +ETLSTLRYA+RA+ I+NKP +N DP A L ++++++
Sbjct: 300 LGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKK 359
Query: 361 LQVLLLQ-----AHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQ 415
L+ +L Q + L + +P + + L+ Q +++ + + + L + + +
Sbjct: 360 LKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLP--QPVIQHDVEAEKQLIRE--EYEE 415
Query: 416 MLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQ 475
L R+ + ++ A+LEE A + + TLE+ KE ++ +
Sbjct: 416 RLARLKADYKAEQESRARLEE--DITAMRNSYDVRLSTLEENLRKETEAVLQVGVLYKAE 473
Query: 476 LSDETVACTAAAIDTAVEEEAQVE----TSPETSRSSDAFTTQHALHQAQMSK 524
+ ++A A + E V+ ++ +T S D TQ + A++ K
Sbjct: 474 VMSRAEFASSAEYPPAFQYETVVKPKVFSTTDTLPSDDVSKTQVSSRFAELPK 526
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 285 bits (728), Expect = 2e-76
Identities = 183/471 (38%), Positives = 273/471 (57%), Gaps = 32/471 (6%)
Query: 5 VKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTD-----KSFTYDFVF---- 55
+ G V+VA+R RP +E S+ + + T ++ + KSF++D+ +
Sbjct: 1 MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHT 60
Query: 56 ---DPC-TEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPT 111
DPC Q V+N ++ F+GYN + AYGQTG+GK+Y+M G ++ E
Sbjct: 61 SPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMG-----KQEESQ 115
Query: 112 VGIIPRVIQLLFKEIDKKSDFE--FTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKE 169
GIIP++ + LF++I+ + E ++++VSY+EIY E + DLL P + K + +RE P
Sbjct: 116 AGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNP-KNKGNLRVREHPLL 174
Query: 170 GIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDK- 228
G + L++ V D ++ GN +RTVA+T MN SSRSHA+FTI Q+K ++
Sbjct: 175 GPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNET 234
Query: 229 NCSFR--SKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD----DKK 282
N S SK+ LVDLAGSER T A+G RLKEG NIN+ L LG VISAL + KK
Sbjct: 235 NLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKK 294
Query: 283 GSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIV 342
F+PYRDS LT LL+++LGGNS T M+A +SPAD N +ETLSTLRYADRA++IK ++
Sbjct: 295 TDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVI 354
Query: 343 NIDPHTAELNHLKQQVQQLQVLL-LQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEK 401
N DP+ + LK++V +L+ LL Q G + S+ + S + L
Sbjct: 355 NEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTSVTSI 414
Query: 402 LSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEE-LRQHVACKLDLQKLV 451
R +S G+ A +ER+ +E++ +LN EE LR+ A +++ + L+
Sbjct: 415 QERIMSTPGGEEA--IERLKESEKIIAELNETWEEKLRKTEAIRMEREALL 463
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 285 bits (728), Expect = 2e-76
Identities = 183/471 (38%), Positives = 273/471 (57%), Gaps = 32/471 (6%)
Query: 5 VKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTD-----KSFTYDFVF---- 55
+ G V+VA+R RP +E S+ + + T ++ + KSF++D+ +
Sbjct: 1 MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHT 60
Query: 56 ---DPC-TEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPT 111
DPC Q V+N ++ F+GYN + AYGQTG+GK+Y+M G ++ E
Sbjct: 61 SPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMG-----KQEESQ 115
Query: 112 VGIIPRVIQLLFKEIDKKSDFE--FTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKE 169
GIIP++ + LF++I+ + E ++++VSY+EIY E + DLL P + K + +RE P
Sbjct: 116 AGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNP-KNKGNLRVREHPLL 174
Query: 170 GIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDK- 228
G + L++ V D ++ GN +RTVA+T MN SSRSHA+FTI Q+K ++
Sbjct: 175 GPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNET 234
Query: 229 NCSFR--SKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD----DKK 282
N S SK+ LVDLAGSER T A+G RLKEG NIN+ L LG VISAL + KK
Sbjct: 235 NLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKK 294
Query: 283 GSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIV 342
F+PYRDS LT LL+++LGGNS T M+A +SPAD N +ETLSTLRYADRA++IK ++
Sbjct: 295 TDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVI 354
Query: 343 NIDPHTAELNHLKQQVQQLQVLL-LQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEK 401
N DP+ + LK++V +L+ LL Q G + S+ + S + L
Sbjct: 355 NEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTSVTSI 414
Query: 402 LSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEE-LRQHVACKLDLQKLV 451
R +S G+ A +ER+ +E++ +LN EE LR+ A +++ + L+
Sbjct: 415 QERIMSTPGGEEA--IERLKESEKIIAELNETWEEKLRKTEAIRMEREALL 463
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 284 bits (726), Expect = 4e-76
Identities = 279/950 (29%), Positives = 453/950 (47%), Gaps = 100/950 (10%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKAV 69
++V R RPL EI G + F ET VV+G K + +D V P T QE+V+N
Sbjct: 9 IKVMCRFRPLNEAEILRGDKFIPKFKGDET-VVIGQGKPYVFDRVLPPNTTQEQVYNACA 67
Query: 70 APLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEI-DK 128
++K + +GYN T+ AYGQT SGKT++M G Q +GIIPR+ +F I
Sbjct: 68 KQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQ----LMGIIPRIAHDIFDHIYSM 123
Query: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
+ EF +KVSY EIY ++I DLL S K + + ED + G TE+ V + +
Sbjct: 124 DENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLAVHEDKNRVPYVKGCTERFVSSPEEVM 181
Query: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK-KSDKNCSFRSKLHLVDLAGSERQ 247
+++G +R VA T MN SSRSH+IF I+I+Q +++K S KL+LVDLAGSE+
Sbjct: 182 DVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLS--GKLYLVDLAGSEKV 239
Query: 248 KKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDSLGGNSHT 307
KT AEG L E NIN+ L LGNVISAL + K + VPYRDSK+TR+LQDSLGGN T
Sbjct: 240 SKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK-THVPYRDSKMTRILQDSLGGNCRT 298
Query: 308 LMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNH-----------LKQ 356
++ C SP+ N ET STL + RA+ IKN VN++ E LK
Sbjct: 299 TIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKN 358
Query: 357 QVQQLQVLLLQ-AHGGTLP--GSINAEPSENLQ-----SLMEKNQSLV-----EENEKLS 403
+Q L++ L + +G +P I+A+ +NL+ +++ +V EE EK
Sbjct: 359 VIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYD 418
Query: 404 RCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVA-CKLDLQKLVETL-----EDQ 457
+S Q + I Q+ EKL ++ + + +A + D +K+ E L E++
Sbjct: 419 EEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENE 478
Query: 458 ELKENV-EIICNLQQLITQLSDET--VACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQ 514
K+ V E++ L++L ++ V A + +E AQ T+ T++ + +
Sbjct: 479 AAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQE 538
Query: 515 HALHQAQMSKEVVELNNALALKEALVRKMTQND-NQLQPIQFQYQDNIKNLELEVINLQK 573
+ HQ + + E+ LN L + + ND L + ++ L + ++
Sbjct: 539 LSNHQKKRATEI--LNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKS 596
Query: 574 EKEELV---RELQTAKKNVNQAKLSEHR-----HKLLQELEGQIADLKKKL-NEQSKLLK 624
E + LV ++L++A+ + N+ + R L+ + E +I L + N + K +
Sbjct: 597 EVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQ 656
Query: 625 LKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQY 684
L+ES + L++E+ +L Q K F Q K+K+ +Q E +K
Sbjct: 657 LEESQD----SLSEEL-------AKLRAQEKMHEVSF-QDKEKEHLTRLQDAEEMKKALE 704
Query: 685 ELLKLERN-FQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARV 743
+ ++ R QKQ S LR + EE ++D QK + +K
Sbjct: 705 QQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDY----------- 753
Query: 744 RNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLS 803
N++++ E K LL D++ A++ ++ E+ SRE L
Sbjct: 754 -----NKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRE------------LQ 796
Query: 804 EVHG-QVLESEDCITKQIESLETEMELRSAQIADLQQ-KLLDAESEDRPKQCWENIATIL 861
+H + L +D T+ +S+E + + A Q+ L+ E K + +
Sbjct: 797 TLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNA 856
Query: 862 EAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSE 911
+ +C L L L ++ V LE++L+++K + +K +E + E
Sbjct: 857 DLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKE 906
Score = 65.5 bits (158), Expect = 3e-10
Identities = 94/441 (21%), Positives = 193/441 (43%), Gaps = 33/441 (7%)
Query: 563 NLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQEL--EGQIADLKKKLNEQS 620
NLEL +K+ E+ + +T K + ++ +R + + + + QI+ +K E
Sbjct: 334 NLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPC 393
Query: 621 KLLKLKESTERTVSKLNQEIWMMKNQRVQ-LMRQMKEDAEKFRQWKQKKDKEVIQLKERD 679
+ ++ V+ ++ E ++ + L RQ+ + ++ Q Q +K Q+ ++D
Sbjct: 394 DNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQD 453
Query: 680 RKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQRE--VTDKRKETQSHGKE 737
L R+++K L R E AA +K+ LQ E V +K + K
Sbjct: 454 EL----LASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKT 509
Query: 738 GIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRK 797
++ + L + + +T+ L +L +K A +++ L K+ E
Sbjct: 510 RANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLL-LKDLGEIGGIIGTN 568
Query: 798 CTFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENI 857
+L++V+G + E I +++E++ + + ++L A+ + K N
Sbjct: 569 DVKTLADVNGVIEEEFTMARLYISKMKSEVK----SLVNRSKQLESAQMDSNRKM---NA 621
Query: 858 ATILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQ 917
+ A C L L+S H K++ SL + ++ L E Q+ SE +L+
Sbjct: 622 SERELAACQL------LISQ--HEAKIK-SLTDYMQNMEQKRRQLEESQDSLSEELAKLR 672
Query: 918 AELVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVC 977
A+ E Q+K +++LQ+++ +K LE QQ+ S + ++L ++R+
Sbjct: 673 AQEKMHEVSFQDKEKEHLTRLQDAEEMKKALE-------QQMESHREAHQKQLSRLRDEI 725
Query: 978 EQNQQLLQENEIIKQKLILLQ 998
E+ Q+++ E + QKL L Q
Sbjct: 726 EEKQKIIDEIRDLNQKLQLEQ 746
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 281 bits (720), Expect = 2e-75
Identities = 216/672 (32%), Positives = 342/672 (50%), Gaps = 63/672 (9%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVV----GT----DKSFTYDFVFDPCTEQ 61
VRV +RCRP+ KE + + QV V GT K+FT+D V+D +Q
Sbjct: 10 VRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQ 69
Query: 62 EEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQL 121
E++++ PL+ + +G+N T+ AYGQTG+GKTY+M G ++ G+IP
Sbjct: 70 FELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKR----GVIPNSFDH 125
Query: 122 LFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTV 181
+F I + + ++ ++ SYLEIY EEI DLL + K ++ ++E P G+ + L+
Sbjct: 126 IFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTK-RLELKERPDTGVYVKDLSSFVT 184
Query: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKS--DKNCSFRSKLHLV 239
+ + GN +R+V +T MN SSRSHAIF I+IE + +N KL+LV
Sbjct: 185 KSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLV 244
Query: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQD 299
DLAGSERQ KT A+G+RLKE IN L LGNVISAL D K + +PYRDSKLTRLLQD
Sbjct: 245 DLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKS-THIPYRDSKLTRLLQD 303
Query: 300 SLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQ 359
SLGGN+ T+M+A V PA N+EETL+TLRYA+RA+ IKNKP VN DP A L ++++
Sbjct: 304 SLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIA 363
Query: 360 QLQVLL------------LQAHGGTLPGSINAEPSENLQSLME---KNQSLVEENEKL-- 402
+L+ L + GG G E E + E K+ E+ EKL
Sbjct: 364 RLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEI 423
Query: 403 -SRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKE 461
R + + A+ R++ ++ K+E+LR+ L ++ +E + L
Sbjct: 424 EKRAIVEDHSLVAEEKMRLL------KEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVG 477
Query: 462 NVEII--CNLQQLITQLSDETVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQ 519
I+ N QQ I + + +A E++ + + S D T +
Sbjct: 478 GKNIVDHTNEQQKILEQKRQEIA----------EQKRREREIQQQMESRDEETLELKETY 527
Query: 520 AQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELV 579
+ + +EV + +K+ + ++LQ ++ + D + E L++ + EL
Sbjct: 528 SSLQQEV----------DIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELT 577
Query: 580 RELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQE 639
REL+ + E + K++ + KL+ ++ L+ ++ +R VS + +
Sbjct: 578 RELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLHPITR-LENQQMMKRPVSAVGYK 636
Query: 640 IWMMKNQRVQLM 651
+ ++ R+ +M
Sbjct: 637 RPLSQHARMSMM 648
Score = 46.2 bits (108), Expect = 2e-04
Identities = 54/264 (20%), Positives = 121/264 (45%), Gaps = 21/264 (7%)
Query: 613 KKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEV 672
K ++NE K L+E E +++L ++ R + + +E ++++++
Sbjct: 343 KPRVNEDPKDALLREFQEE-IARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGE 401
Query: 673 IQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQ 732
+E D K Y + E+ ++ +++ + + A ++++ +K++++ D R+E
Sbjct: 402 EGEEEGDDKDDYWREQQEKLEIEKRAIVE---DHSLVAEEKMRLLKEKEKKMEDLRREKD 458
Query: 733 SHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPP 792
+ E + A+++ E +++V + H N E +KIL Q ++ E+K
Sbjct: 459 A--AEMLGAKIK---AMESKLLVGGKNIVDHTN---EQQKILEQKRQEIAEQKRREREIQ 510
Query: 793 PKLRKC---TFSLSEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDR 849
++ T L E + + + D TK+++ L ++++ A+I DLQ E +
Sbjct: 511 QQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQ------EEHIK 564
Query: 850 PKQCWENIATILEAKCALKYLIGE 873
+Q E L + LK+LI E
Sbjct: 565 ERQELEQTQNELTRELKLKHLIIE 588
Score = 33.5 bits (75), Expect = 1.3
Identities = 34/212 (16%), Positives = 96/212 (45%), Gaps = 31/212 (14%)
Query: 577 ELVRELQTAKKNV--NQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVS 634
E +L+ K+ + + + ++E + +LL+E E ++ DL+++ K++ E
Sbjct: 416 EQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRRE----------KDAAEM--- 462
Query: 635 KLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQ 694
L +I M+++ + + + + + ++ ++K +E+ + K R+R+ Q ++
Sbjct: 463 -LGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQM-------- 513
Query: 695 KQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVM 754
+E K +LQ++ ++ K+ + + + A + + I+
Sbjct: 514 -------ESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKER 566
Query: 755 VSTEEAKRHLNDLLEDRKILAQDVVQLKEKKE 786
E+ + L L+ + ++ ++ + L+EK +
Sbjct: 567 QELEQTQNELTRELKLKHLIIENFIPLEEKSK 598
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 280 bits (716), Expect = 6e-75
Identities = 261/956 (27%), Positives = 446/956 (46%), Gaps = 90/956 (9%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKAV 69
++V R RPL E++ G + F GE VV+ + K + +D VF T QE+V+N
Sbjct: 9 IKVMCRFRPLNESEVNRGDKYIAKF-QGEDTVVIAS-KPYAFDRVFQSSTSQEQVYNDCA 66
Query: 70 APLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEI-DK 128
++K + +GYN T+ AYGQT SGKT++M G + + +GIIPR++Q +F I
Sbjct: 67 KKIVKDVLEGYNGTIFAYGQTSSGKTHTMEG----KLHDPEGMGIIPRIVQDIFNYIYSM 122
Query: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
+ EF +KVSY EIY ++I DLL S K +++ ED + G TE+ V + +
Sbjct: 123 DENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLSVHEDKNRVPYVKGCTERFVCSPDEVM 180
Query: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLVDLAGSERQK 248
+++G ++R VA T MN SSRSH+IF I+++Q + KL+LVDLAGSE+
Sbjct: 181 DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQ-KLSGKLYLVDLAGSEKVS 239
Query: 249 KTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDSLGGNSHTL 308
KT AEG L E NIN+ L LGNVISAL + ++VPYRDSK+TR+LQDSLGGN T
Sbjct: 240 KTGAEGAVLDEAKNINKSLSALGNVISALAEGS--TYVPYRDSKMTRILQDSLGGNCRTT 297
Query: 309 MIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQA 368
++ C SP+ N ET STL + RA+ IKN VN++ TAE K + ++ + +L+
Sbjct: 298 IVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVE-LTAEQWKKKYEKEKEKNKILRN 356
Query: 369 HGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNE 428
L +N +N V +E+ + KA + + + I LT N+
Sbjct: 357 TIQWLENELN----------RWRNGETVPIDEQFDK--EKANLEAFTVDKDITLT---ND 401
Query: 429 KLNAKLEEL-----RQHVACKLDLQKLVETLE--DQELKENVEIICNLQQLITQLSDETV 481
K + + + C+ ++ KL + L+ D+E+ + +++ ++L TQ+ D
Sbjct: 402 KPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLV---EKLKTQMLD--- 455
Query: 482 ACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVR 541
Q E T R D + QA+ E+ L E L
Sbjct: 456 ---------------QEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAV 500
Query: 542 KMTQNDNQLQPIQFQYQ---DNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHR 598
Q +++ +Y+ D + + ++ E ++L KK A++
Sbjct: 501 NYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRA--AEMMASL 558
Query: 599 HKLLQELEGQIADLKKKLNEQSKLLKLKESTERT-VSKLNQEIWMMKNQRVQLMRQMKED 657
K L E+ + + K E + ++ + + R +SK+ E+ M + QL E
Sbjct: 559 LKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTES 618
Query: 658 AEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDA 717
+K ++ +KE+ + R + + ++ L Q R+ E A ++ L
Sbjct: 619 NKKM----EENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQ- 673
Query: 718 LQKQREVTDKRKE------TQSHGKEGIAARV---RNWLGNEIEVMVSTEEAKRHLNDLL 768
L+ Q +V + KE T + K+ + ++ R +I + EAK L L
Sbjct: 674 LRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDL 733
Query: 769 ED---RKILAQDVVQLKEK--KESRENPPPKLRKCTF---SLSEVHGQVLESEDCITKQI 820
+D + +L Q+ ++++ + K + + KL + T + + E+ + K++
Sbjct: 734 QDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKEL 793
Query: 821 ESLETEMELRSAQIADLQQKLLDAESED-----RPKQCWENIATILEAKCAL-KYLIGEL 874
++L +L +A +K + +S+D KQ + LE + K L+ +
Sbjct: 794 QTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDN 853
Query: 875 VSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEK 930
+ + KLE LR + ++ L E + + S Q E+ R+++ + K
Sbjct: 854 ADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSK 909
Score = 70.1 bits (170), Expect = 1e-11
Identities = 78/372 (20%), Positives = 164/372 (44%), Gaps = 45/372 (12%)
Query: 663 QWKQKKDKEVIQLK-----------ERDRKRQYELLKLERNFQKQSSVLRRKT--EEAAA 709
QWK+K +KE + K E +R R E + ++ F K+ + L T ++
Sbjct: 339 QWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITL 398
Query: 710 ANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLE 769
N + A+ TD + +E IA + + E+ ++ ++ +L+
Sbjct: 399 TNDKPATAIGVIGNFTDAERRKC---EEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLD 455
Query: 770 DRKILA-----QDVVQLKEKKESRENPPPK--LRKCTFSLSEV---HGQVLESEDCITKQ 819
++LA QD +Q + + EN K +++ +L E+ + Q + + TK+
Sbjct: 456 QEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKE 515
Query: 820 IESLETEMELRSAQIADLQQKL--LDAESEDRPKQCWENIATILEAKCALKYLIG----- 872
E L E+ +SA +A + +L L + + K+ E +A++L+ + +G
Sbjct: 516 YELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVK 575
Query: 873 ----------ELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVR 922
E ++++++K+++ ++ C ++ E E E EL A +R
Sbjct: 576 QPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLR 635
Query: 923 MEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQQ 982
+ Q H+ K+ L LQ + ++QLE+S ++LV L+ Q++ E +E + Q
Sbjct: 636 ISQ-HEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQ-LRAQEKVHEMEKEHLNKVQT 693
Query: 983 LLQENEIIKQKL 994
+ + ++Q++
Sbjct: 694 ANEVKQAVEQQI 705
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 279 bits (713), Expect = 1e-74
Identities = 237/769 (30%), Positives = 365/769 (47%), Gaps = 78/769 (10%)
Query: 44 GTDKSFTYDFVFDPCTE--------QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKT 95
G K F YD F E Q+ VF +++ F GYNA + AYGQTGSGK+
Sbjct: 51 GQPKVFAYDHCFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKS 110
Query: 96 YSMGGAYTAEQENEPTVGIIPRVIQLLFKEIDKKSDFE--FTLKVSYLEIYNEEILDLLC 153
Y+M G TA+Q G+IPR+ LF+ K+ + E F ++VSY+EIYNE++ DLL
Sbjct: 111 YTMMG--TADQP-----GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLD 163
Query: 154 PSREKAQINIREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSH 213
P + + +RE G + GL++ V D S + +GN SRTVA+T MN +SSRSH
Sbjct: 164 PKGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSH 223
Query: 214 AIFTISIEQRK---KSDKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCL 270
A+F I++ KS + KL LVDLAGSER KT A GDRLKEG NIN+ L L
Sbjct: 224 AVFKITLTHTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTL 283
Query: 271 GNVISALGDDKKGS----FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLST 326
G VISAL D G FVPYRDS LT LL+DSLGGNS T M+A VSPA N +ETLST
Sbjct: 284 GLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLST 343
Query: 327 LRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQ 386
LRYADRA+ I N +VN DP+ + L+++V++L+ L +A A S L+
Sbjct: 344 LRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKA---------EAMKSPELK 394
Query: 387 SLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEEL---RQHVAC 443
+E+++ L++E T E++ TE++ ++ +LE L Q
Sbjct: 395 DRLEESEKLIQE-------------MTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGI 441
Query: 444 KLDLQK--LVETLEDQELKENVEIICNLQQLITQLSDETVACTAAAI-----DTAVEEEA 496
K+ K LV D L E + LI + + + I + E
Sbjct: 442 KVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCIIDITSEG 501
Query: 497 QVETSPE----TSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQP 552
QV +P+ T + + ++ LH + + N+ L +K + +++ Q
Sbjct: 502 QVMLTPQKNTRTFVNGSSVSSPIQLHHG--DRILWGNNHFFRLNLPKKKKKAEREDEDQD 559
Query: 553 IQFQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKL--SEHRHKLLQELEGQIA 610
+ +++ + L+++ + + E+ + A+ V L ++ +L LE Q
Sbjct: 560 PSMKNENSSEQLDVDGDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHE 619
Query: 611 DLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDK 670
+ K+ E+ +L+ + E+ +L+ E ++ + ++ RQW +
Sbjct: 620 EEKRSALERQRLM-YEHELEQLRRRLSPEKQNCRSMD-RFSFHSPSAQQRLRQWAE---- 673
Query: 671 EVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKR--LKDALQKQREVTDKR 728
ER+ L++L K + ++R A +KR K LQ D
Sbjct: 674 ------EREATLNNSLMRLREQIVKANLLVREANYIAEELDKRTEYKVTLQIPASSLDAN 727
Query: 729 KETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQD 777
++ S E R G +I + + + DL ++ K +D
Sbjct: 728 RKRGSLLSEPAIQVRRKGKGKQIWSLEKLDNRLLDMRDLYQEWKECEED 776
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 277 bits (708), Expect = 5e-74
Identities = 267/952 (28%), Positives = 448/952 (47%), Gaps = 77/952 (8%)
Query: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTE 60
M E ++V R RPL EI G + F G+ VV+G K + +D VF P T
Sbjct: 1 MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIF-QGDDSVVIG-GKPYVFDRVFPPNTT 58
Query: 61 QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQ 120
QE+V++ ++K + GYN T+ AYGQT SGKT++M G Q +GIIPR+ +
Sbjct: 59 QEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQ----LMGIIPRIAR 114
Query: 121 LLFKEI-DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEK 179
+F I + EF +KVSY EIY ++I DLL + K +++ ED + G TE+
Sbjct: 115 DIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVT--KTNLSVHEDKNRVPFVKGCTER 172
Query: 180 TVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLV 239
V + + +++G ++R VA T MN SSRSH+IF I+I+Q + KL+LV
Sbjct: 173 FVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQ-KLSGKLYLV 231
Query: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQD 299
DLAGSE+ KT AEG L E NIN+ L LGNVISAL + K S+VPYRDSK+TR+LQD
Sbjct: 232 DLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK-SYVPYRDSKMTRILQD 290
Query: 300 SLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQ 359
SLGGN T M C SP+ N ET STL + RA+ IKN VN++ TAE K + +
Sbjct: 291 SLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLE-LTAEQWKKKYEKE 349
Query: 360 QLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLER 419
+ + +A T+ + AE S +N V E E+L+ + A A++ E
Sbjct: 350 KEKT---KAQKETI-AKLEAELSR------WRNGENVPETERLA---GEEAALGAELCEE 396
Query: 420 IILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDE 479
+ + + + EE +++ + ++++L + L+D++ + N + QLI +L +
Sbjct: 397 TPVNDNSSIVVRIAPEERQKY---EEEIRRLYKQLDDKDDEINQQ-----SQLIEKLKQQ 448
Query: 480 TVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALAL---- 535
+ + T + E +DA + KEV++ LA+
Sbjct: 449 MLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDE--------VKEVLQALEELAVNYDQ 500
Query: 536 KEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQK----EKEELVRELQTAKKNVNQ 591
K V + +Q + L Q + +LE E+ LQ+ +++ + L K++++
Sbjct: 501 KSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSE 560
Query: 592 AK--LSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQ 649
+ KL E+ G I + + + + K+K + V + Q ++N +V+
Sbjct: 561 FSVIVGNGEIKLPVEISGAIEE--EFTVARLYISKIKSEVKSVVKRCRQ----LENLQVE 614
Query: 650 LMRQMKEDAEKFRQWK---QKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEE 706
R+M+ + + + + ++ L E + + + LE ++ S L + +
Sbjct: 615 CHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQ 674
Query: 707 AAAANKRLKDALQKQREVTDKRK--ETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHL 764
LKD ++ + +K E Q R L +EI T + + L
Sbjct: 675 ETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDL 734
Query: 765 NDLLE-DRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLES----EDCITKQ 819
N L+ + + L D +LK ++ + KL++ TF L E H Q + E+ + ++
Sbjct: 735 NQKLQLELEKLQADYEKLKSEEHEKST---KLQELTF-LYERHEQSKQDLKGLEETVARE 790
Query: 820 IESLETEMELRSAQIADLQQKLLDAESED-----RPKQCWENIATILEAKCAL-KYLIGE 873
+++L +L + +K + E ED KQ + LE + K L+ +
Sbjct: 791 LQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRD 850
Query: 874 LVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQ 925
+ + KLE LR + ++ L E + + + Q E+ R+++
Sbjct: 851 NADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKE 902
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 276 bits (707), Expect = 7e-74
Identities = 181/479 (37%), Positives = 276/479 (57%), Gaps = 46/479 (9%)
Query: 7 GIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVG------TDKSFTYDFVFDPCTE 60
G V+VA+R RP +E+S + C+ + G T +V T KSF++D+ + T
Sbjct: 3 GASVKVAVRVRPFNSREMSRDSK-CIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTS 61
Query: 61 --------QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV 112
Q++V+ +++ F+GYN + AYGQTG+GK+Y+M G +Q+
Sbjct: 62 PEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQ----- 116
Query: 113 GIIPRVIQLLFKEIDKKSD--FEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEG 170
GIIP++ + LF I+ ++ ++++VSY+EIY E + DLL P + K + +RE P G
Sbjct: 117 GIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNP-KNKGNLRVREHPLLG 175
Query: 171 IKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKK-SDKN 229
+ L++ V D ++ GN +RTVA+T MN SSRSHA+F I Q++ ++ N
Sbjct: 176 PYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETN 235
Query: 230 CSFR--SKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD-------- 279
+ SK+ LVDLAGSER T A+G RLKEG NIN+ L LG VISAL +
Sbjct: 236 ITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKN 295
Query: 280 --DKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIK 337
KK F+PYRDS LT LL+++LGGNS T M+A +SPAD N +ETLSTLRYADRA++I+
Sbjct: 296 KKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIR 355
Query: 338 NKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINA----EPSENLQSLMEKNQ 393
++N DP+ + LK +V +L+ LL G + NA PS +L +L +
Sbjct: 356 CNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDMTNALVGMSPSSSLSALSSRAA 415
Query: 394 SLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEE-LRQHVACKLDLQKLV 451
S+ +E++ A + + +ER+ TE++ +LN EE LR+ A +++ + L+
Sbjct: 416 SVSSLHERI-----LFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALL 469
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 275 bits (703), Expect = 2e-73
Identities = 191/455 (41%), Positives = 257/455 (56%), Gaps = 56/455 (12%)
Query: 10 VRVALRCRPLVPKEIS---------EGCQMCLSFVPGET-QVVVGTDKSFTYDFVFDPCT 59
V+VA+R RP+ +E+ EG Q L P T Q K F +D+ F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65
Query: 60 E--------QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPT 111
E QE VF +++ F+GYNA + AYGQTGSGK++SM G AEQ
Sbjct: 66 ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH--AEQ----- 118
Query: 112 VGIIPRVIQLLFKEI--DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKE 169
+G+IPR+ LFK I ++ F ++VSY+EIYNE++ DLL P + + +RE
Sbjct: 119 LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 170 GIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK---KS 226
G + GL++ V D S + +GN SRTVA+T MN +SSRSHA+F I I Q +S
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 227 DKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGS-- 284
+ SK+ LVDLAGSER KT A G+RLKEG NIN+ L LG VIS+L D G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 285 --FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIV 342
FVPYRDS LT LL+D+LGGNS T MIA +SPA N EETLSTLRYADRA++I N +V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 343 NIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKL 402
N DP+ + L+++V++L+ L QA P L EK +EE+EKL
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAP------------ELKEK----LEESEKL 402
Query: 403 SRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEEL 437
+ L T E++ TE++ ++ +LE +
Sbjct: 403 IKEL------TVTWEEKLRKTEEIAQERQRQLESM 431
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 275 bits (703), Expect = 2e-73
Identities = 191/455 (41%), Positives = 257/455 (56%), Gaps = 56/455 (12%)
Query: 10 VRVALRCRPLVPKEIS---------EGCQMCLSFVPGET-QVVVGTDKSFTYDFVFDPCT 59
V+VA+R RP+ +E+ EG Q L P T Q K F +D+ F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65
Query: 60 E--------QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPT 111
E QE VF +++ F+GYNA + AYGQTGSGK++SM G AEQ
Sbjct: 66 ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH--AEQ----- 118
Query: 112 VGIIPRVIQLLFKEI--DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKE 169
+G+IPR+ LFK I ++ F ++VSY+EIYNE++ DLL P + + +RE
Sbjct: 119 LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 170 GIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK---KS 226
G + GL++ V D S + +GN SRTVA+T MN +SSRSHA+F I I Q +S
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 227 DKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGS-- 284
+ SK+ LVDLAGSER KT A G+RLKEG NIN+ L LG VIS+L D G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 285 --FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIV 342
FVPYRDS LT LL+D+LGGNS T MIA +SPA N EETLSTLRYADRA++I N +V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 343 NIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKL 402
N DP+ + L+++V++L+ L QA P L EK +EE+EKL
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAP------------ELKEK----LEESEKL 402
Query: 403 SRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEEL 437
+ L T E++ TE++ ++ +LE +
Sbjct: 403 IKEL------TVTWEEKLRKTEEIAQERQRQLESM 431
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 275 bits (703), Expect = 2e-73
Identities = 191/455 (41%), Positives = 257/455 (56%), Gaps = 56/455 (12%)
Query: 10 VRVALRCRPLVPKEIS---------EGCQMCLSFVPGET-QVVVGTDKSFTYDFVFDPCT 59
V+VA+R RP+ +E+ EG Q L P T Q K F +D+ F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65
Query: 60 E--------QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPT 111
E QE VF +++ F+GYNA + AYGQTGSGK++SM G AEQ
Sbjct: 66 ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH--AEQ----- 118
Query: 112 VGIIPRVIQLLFKEI--DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKE 169
+G+IPR+ LFK I ++ F ++VSY+EIYNE++ DLL P + + +RE
Sbjct: 119 LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 170 GIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK---KS 226
G + GL++ V D S + +GN SRTVA+T MN +SSRSHA+F I I Q +S
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 227 DKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGS-- 284
+ SK+ LVDLAGSER KT A G+RLKEG NIN+ L LG VIS+L D G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 285 --FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIV 342
FVPYRDS LT LL+D+LGGNS T MIA +SPA N EETLSTLRYADRA++I N +V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 343 NIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKL 402
N DP+ + L+++V++L+ L QA P L EK +EE+EKL
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAP------------ELKEK----LEESEKL 402
Query: 403 SRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEEL 437
+ L T E++ TE++ ++ +LE +
Sbjct: 403 IKEL------TVTWEEKLRKTEEIAQERQRQLESM 431
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 275 bits (703), Expect = 2e-73
Identities = 191/455 (41%), Positives = 257/455 (56%), Gaps = 56/455 (12%)
Query: 10 VRVALRCRPLVPKEIS---------EGCQMCLSFVPGET-QVVVGTDKSFTYDFVFDPCT 59
V+VA+R RP+ +E+ EG Q L P T Q K F +D+ F
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65
Query: 60 E--------QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPT 111
E QE VF +++ F+GYNA + AYGQTGSGK++SM G AEQ
Sbjct: 66 ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGH--AEQ----- 118
Query: 112 VGIIPRVIQLLFKEI--DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKE 169
+G+IPR+ LFK I ++ F ++VSY+EIYNE++ DLL P + + +RE
Sbjct: 119 LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 170 GIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK---KS 226
G + GL++ V D S + +GN SRTVA+T MN +SSRSHA+F I I Q +S
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 227 DKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGS-- 284
+ SK+ LVDLAGSER KT A G+RLKEG NIN+ L LG VIS+L D G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 285 --FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIV 342
FVPYRDS LT LL+D+LGGNS T MIA +SPA N EETLSTLRYADRA++I N +V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 343 NIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKL 402
N DP+ + L+++V++L+ L QA P L EK +EE+EKL
Sbjct: 359 NEDPNAKVIRELREEVEKLREQLSQAEAMKAP------------ELKEK----LEESEKL 402
Query: 403 SRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEEL 437
+ L T E++ TE++ ++ +LE +
Sbjct: 403 IKEL------TVTWEEKLRKTEEIAQERQRQLESM 431
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 271 bits (694), Expect = 2e-72
Identities = 244/849 (28%), Positives = 407/849 (47%), Gaps = 96/849 (11%)
Query: 2 KEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTD--------KSFTYDF 53
K+E KG ++V +RCRP E + P +V V T K++T+D
Sbjct: 11 KKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDM 70
Query: 54 VFDPCTEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQE----NE 109
VF T+Q +V+ V P++ + GYN T+ AYGQTG+GKT++M G + +E +
Sbjct: 71 VFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEED 130
Query: 110 PTVGIIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQ-INIREDP- 167
P GIIPR + +F+++ EF++KVS LEIYNEE+ DLL PS + ++ + + +DP
Sbjct: 131 PLAGIIPRTLHQIFEKLTDNGT-EFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPR 189
Query: 168 -KEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKS 226
K G+ I GL E TV + LE+G RT A+T MN+ SSRSH++F+++I ++ +
Sbjct: 190 NKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETT 249
Query: 227 --DKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGS 284
+ KL+LVDLAGSE ++ A R +E NIN+ LL LG VI+AL + +
Sbjct: 250 IDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE--RTP 307
Query: 285 FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNI 344
VPYR+SKLTR+LQDSLGG + T +IA +SPA NLEETLSTL YA RA+ I NKP VN
Sbjct: 308 HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQ 367
Query: 345 DPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLV-EENEK-L 402
L +K+ ++++ L +L + EKN + EEN + +
Sbjct: 368 KLTKKAL--IKEYTEEIERL-----------------KRDLAAAREKNGVYISEENFRVM 408
Query: 403 SRCLSKAAGQTAQMLERI-ILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLE-DQELK 460
S L+ Q +++E+I + E++N ++ + CK DLQ + LE Q+
Sbjct: 409 SGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHL 468
Query: 461 ENVEIICNLQQLIT---QLSDETVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHAL 517
+ ++ ++ IT + ++E + A+ + VE ET+ + S + A+
Sbjct: 469 QETKLQLVKEEYITSALESTEEKLHDAASKLLNTVE-----ETTKDVSGLHSKLDRKKAV 523
Query: 518 HQAQMSKEVV---ELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKE 574
Q + + LN+ E L++ + + + N+ L V L
Sbjct: 524 DQHNAEAQDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNL--LSSSVSALDTI 581
Query: 575 KEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLK--LKESTERT 632
+ L + +NV+ +S+ + +L+E + A+ K L E +LK L S E
Sbjct: 582 TTVALGSLTSIPENVS-THVSQIFNMILKE-QSLAAESKTVLQELINVLKTDLLSSLEMI 639
Query: 633 VSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKD---------------KEVIQLKE 677
+S I + +Q + + A+K K++ D + L E
Sbjct: 640 LSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVE 699
Query: 678 RDRK--------------RQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDAL-QKQR 722
++ EL KL + ++ L K E +++ + QK +
Sbjct: 700 SQKQCGNLTEDLKTIKQTHSQELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSK 759
Query: 723 EVTDK---RKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVV 779
++ +K + +G + +RN+ +++ EE+ +H + L + + ++Q+
Sbjct: 760 DIVNKMTFHSQKFCADSDGFSQELRNFNQEGTKLV---EESVKHSDKLNGNLEKISQETE 816
Query: 780 QLKEKKESR 788
Q E +R
Sbjct: 817 QRCESLNTR 825
Score = 36.6 bits (83), Expect = 0.15
Identities = 108/536 (20%), Positives = 215/536 (40%), Gaps = 76/536 (14%)
Query: 501 SPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQ------ 554
SP + + +T H+A+ E+N L K+AL+++ T+ +L+
Sbjct: 337 SPASLNLEETLSTLEYAHRAKNILNKPEVNQKLT-KKALIKEYTEEIERLKRDLAAAREK 395
Query: 555 ---FQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIAD 611
+ ++N + + ++ +++ EL+ ++ ++ +N +++E EL+ +D
Sbjct: 396 NGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEELN--RVTELFMDNKNELDQCKSD 453
Query: 612 LKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKE 671
L+ K E K + T+ + K +++ +L + A K ++ K+
Sbjct: 454 LQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKL----HDAASKLLNTVEETTKD 509
Query: 672 VIQLKER-DRKRQYELLKLERN--FQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKR 728
V L + DRK+ + E F K + L EE +KD KQ+ + +
Sbjct: 510 VSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEEL------IKDGSSKQKAMLEVH 563
Query: 729 K----ETQSHGKEGIAARVRNWLGN--EIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLK 782
K S + LG+ I VST + N +L+++ + A+ L+
Sbjct: 564 KTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTH-VSQIFNMILKEQSLAAESKTVLQ 622
Query: 783 E-----KKESRENPPPKLRKCTFSLSEVHGQV-------LESEDCITKQIESLETEMELR 830
E K + + L S+ +++ Q+ L D I Q + L+ + +
Sbjct: 623 ELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSIL 682
Query: 831 SAQIADLQQKLLDAESEDRPKQCW---ENIATILEAK----CALKYLIGE----LVSSKI 879
+ +LQ+ + + E + KQC E++ TI + C L L E L
Sbjct: 683 CNNLHELQENTICSLVESQ-KQCGNLTEDLKTIKQTHSQELCKLMNLWTERFCALEEKCE 741
Query: 880 HVTKLENSLRQS--KASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQ 937
++ K +S++++ + S + KM F Q ++ + Q + +QE +
Sbjct: 742 NIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQ----ELRNFNQEGTKLVEES 797
Query: 938 LQESQMAEKQLEKSASEKEQ--------------QLVSTLQCQDEELEKMREVCEQ 979
++ S LEK + E EQ Q VS+L +++EL + EV Q
Sbjct: 798 VKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELHNLLEVVSQ 853
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 267 bits (682), Expect = 5e-71
Identities = 214/703 (30%), Positives = 340/703 (48%), Gaps = 100/703 (14%)
Query: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTD--------KSFTYDFVFDPCTEQ 61
++V RCRPL KE + G + L+ QV + K+FT+D V+D ++Q
Sbjct: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQ 70
Query: 62 EEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV-GIIPRVIQ 120
+++++ V PLI + +G+N TV AYGQTG+GKTY+M G + EP + G+IP +
Sbjct: 71 ADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWV-----EPELRGVIPNAFE 125
Query: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
+F I + + ++ ++ SYLEIY EEI DLL K ++ ++E+P+ G+ I L+
Sbjct: 126 HIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGK-RLELKENPETGVYIKDLSSFV 184
Query: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIE-QRKKSDKNCSFR-SKLHL 238
+ + GN +R V ST MN SSRSHAIF I++E + SD R KL+L
Sbjct: 185 TKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNL 244
Query: 239 VDLAGSERQKKTK------------------------AEGDRLKEGININRGLLCLGNVI 274
VDLAGSERQ K A G+R KE IN L LGNVI
Sbjct: 245 VDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVI 304
Query: 275 SALGDDKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRAR 334
+AL ++ + +PYRDSKLTRLLQDSLGGN+ T+M+A + PA + +E+LSTLR+A+RA+
Sbjct: 305 AALAGNRS-THIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAK 363
Query: 335 KIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQS 394
IKNKP VN DP L ++++ +L+ L EK
Sbjct: 364 NIKNKPRVNEDPKDTLLREFQEEIARLKAQL------------------------EKRGM 399
Query: 395 LVEENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETL 454
L + + S KA E ++ V E+ + + H + L+ +E
Sbjct: 400 LGKRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEED---DNNNNHRPPQPILESALEKN 456
Query: 455 EDQELKENVEIICNLQQLITQLSDETVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQ 514
+ L+E E L++ + D+ + E+E +E + R A
Sbjct: 457 MENYLQEQKE---RLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLE---DLRREQQATELL 510
Query: 515 HALHQAQMSKEVV----------ELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNL 564
A ++A SK ++ E L LK + + + + ++Q + L
Sbjct: 511 AAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMEL 570
Query: 565 ELEVINLQKEKEELVRELQT--AKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKL 622
+LQ+E E ++L+ AK +A++ + + ++ + DL++ NEQ++
Sbjct: 571 RGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQ----DLEEAQNEQTRE 626
Query: 623 LKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWK 665
LKLK L E ++ ++ ++M ++ D E+ QWK
Sbjct: 627 LKLK--------YLIIENFIPPEEKNKIMNRLFLDCEE-EQWK 660
Score = 43.1 bits (100), Expect = 0.002
Identities = 42/223 (18%), Positives = 100/223 (44%), Gaps = 30/223 (13%)
Query: 564 LELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLL 623
LE + N +E++E + E + A ++ +++ +SE + KLL+E E + DL+++
Sbjct: 453 LEKNMENYLQEQKERLEEEKAAIQD-DRSLVSEEKQKLLEEKEKMLEDLRRE-------- 503
Query: 624 KLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQ 683
+++TE +K M+++ + R + + + ++ + K +E+ + K R+R+ Q
Sbjct: 504 --QQATELLAAKYK----AMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQ 557
Query: 684 YELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARV 743
E++ + + +E K+LK K + + A +
Sbjct: 558 QEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAK---------------LQAVKAEI 602
Query: 744 RNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKE 786
++ I V EEA+ L+ + ++ ++ + +EK +
Sbjct: 603 QDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNK 645
Score = 40.0 bits (92), Expect = 0.014
Identities = 70/350 (20%), Positives = 140/350 (40%), Gaps = 73/350 (20%)
Query: 692 NFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEI 751
N + ++LR EE A RLK L+K+ + + + S K+ ++A G I
Sbjct: 372 NEDPKDTLLREFQEEIA----RLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVI 427
Query: 752 EVMVSTEEAKRHLNDLLEDRKILAQDVVQ-----LKEKKESRENPPPKLRKCTFSLSEVH 806
E V+ EE + N+ + IL + + L+E+KE E ++ +SE
Sbjct: 428 EAWVAEEEDDNN-NNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEK 486
Query: 807 GQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIATILEAKCA 866
++LE ++ + + + + EL +A+ ++ KLL NI
Sbjct: 487 QKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIG---------GRNIMD------- 530
Query: 867 LKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQ 926
H + + L + A+ ++ E E+Q E++ +++
Sbjct: 531 -------------HTNEQQKMLELKRQEIAEQKRR-----------EREMQQEMMLRDEE 566
Query: 927 HQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQQLLQE 986
E S QE ++ K+L+K + K Q + + +Q Q +E ++R+ E+ Q ++
Sbjct: 567 TMELRGTYTSLQQEVEVKTKKLKKLYA-KLQAVKAEIQDQHDEYIRVRQDLEEAQN--EQ 623
Query: 987 NEIIKQKLILLQVASRQKHLPNDTLLSPDSSFEYIPPKPKPSRVKEKFLE 1036
+K K ++++ +IPP+ K + FL+
Sbjct: 624 TRELKLKYLIIE--------------------NFIPPEEKNKIMNRLFLD 653
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 263 bits (671), Expect = 1e-69
Identities = 234/805 (29%), Positives = 385/805 (47%), Gaps = 109/805 (13%)
Query: 4 EVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFV-------FD 56
+V+ V VA+R RP +E E + F+ G+ V D Y+F+ FD
Sbjct: 353 KVENSQVTVAVRVRPFTKREKIEKASQVV-FMSGKEITVEHPDTKQVYNFIYDVSFWSFD 411
Query: 57 PC----TEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV 112
C Q V+ K APL++ F+G+N + AYGQTGSGK+Y+M G EP
Sbjct: 412 ECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGF-----SEEP-- 464
Query: 113 GIIPRVIQLLFKEIDKKSDFE--FTLKVSYLEIYNEEILDLLCPSREKAQ----INIRED 166
GIIPR + LF ++ +K E + +++S+ E+YNE+I DLL E Q + +RE
Sbjct: 465 GIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREH 524
Query: 167 PKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKS 226
P G + L+ V D S LE GN R A+T MN +SSRSH++FT+ + Q K
Sbjct: 525 PVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 584
Query: 227 -----DKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD-- 279
+ + S+++L+DLAGSER GDRLKEG++IN+ LL LG VISAL +
Sbjct: 585 FVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQA 644
Query: 280 DKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNK 339
+++ F+PYR+S LT LL++SLGGNS T MIA +SPA SN+EETLSTLRYA++AR I N
Sbjct: 645 NQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLIVNI 704
Query: 340 PIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEEN 399
VN D + + LK ++ +L+ S N +P E+ + +E
Sbjct: 705 AKVNEDMNAKLIRELKAEIAKLK--------AAQRNSRNIDP--------ERYRLCRQEI 748
Query: 400 EKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQ----HVACKLD--LQKLVET 453
L L + A+M + + E+ + KL+E ++ + ++D L LV
Sbjct: 749 TSLRMKLHQQERDMAEM--QRVWKEKFEQAEKRKLQETKELQKAGIMFQMDNHLPNLVNL 806
Query: 454 LEDQELKENVEIICNLQQLIT-------------QLSDETVA---CTAAAIDTAVE--EE 495
ED +L E ++ +++ T QLS +A CT V
Sbjct: 807 NEDPQLSE--MLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPV 864
Query: 496 AQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQ--PI 553
+ +T + +H N+ + +++ ++ + D + P
Sbjct: 865 GEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQKG--KRPSGRDTPISEGPK 922
Query: 554 QFQYQDN------IKNLELEVINLQ-KEKEELVRELQTAKKNVNQAKLSEHRHKLLQELE 606
F++ N LE E+ Q K KEE+++ +Q AK+ Q S+ E
Sbjct: 923 DFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQK-----AAYE 977
Query: 607 GQIADLKKKLNEQSKLLKLK-----------ESTERTVSKLNQEIWMMKNQRVQLMRQMK 655
+I L+ +L E+S+ K++ E E+ L QEI++ K +R+++
Sbjct: 978 SKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNK-KRLEMETLAT 1036
Query: 656 EDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLK 715
+ A + + + E ++ +++ ++ ++L+ RN + ++ T + ++ +L
Sbjct: 1037 KQALEDHSIRHARILEALETEKQKIAKEVQILQQNRNNRDKTF-----TVQTTWSSMKLS 1091
Query: 716 DALQKQREVTDKRKETQSHGKEGIA 740
+Q+ ++ K K G+ I+
Sbjct: 1092 MMIQEANAISSKLKTYYVFGRHDIS 1116
Score = 53.1 bits (126), Expect = 2e-06
Identities = 95/481 (19%), Positives = 208/481 (43%), Gaps = 52/481 (10%)
Query: 524 KEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEELVRELQ 583
KE V +N +L ++ +++ NQ + + Y++++ L+ K ++ +
Sbjct: 621 KEGVSINKSLLTLGKVISALSEQANQ-RSVFIPYRESVLTWLLKESLGGNSKTAMIATIS 679
Query: 584 TAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQ------SKLLKLKESTERTVSKLN 637
A N+ + LS R+ L IA + + +N + +++ KLK + +R ++
Sbjct: 680 PAASNIEET-LSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLK-AAQRNSRNID 737
Query: 638 QEIWMMKNQ-----RVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERN 692
E + + Q R++L +Q ++ AE R WK+K + Q ++R + EL K
Sbjct: 738 PERYRLCRQEITSLRMKLHQQERDMAEMQRVWKEKFE----QAEKRKLQETKELQKAGIM 793
Query: 693 FQKQSSVLRR-KTEEAAAANKRLKDALQKQREVTDKRKETQSHGKE--GIA-----ARVR 744
FQ + + E ++ L +++ K K SH + G+ ++
Sbjct: 794 FQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIK 853
Query: 745 NWLGNEIEVMVSTEEAKRHLN--DLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSL 802
N+ G + + + EAK ++N +LE + D V L R N P +++K
Sbjct: 854 NF-GGTVSI-IPVGEAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHPVEVQK----- 906
Query: 803 SEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIATILE 862
G+ D I + E ++ Q+ L+AE ++ + E + ++
Sbjct: 907 ----GKRPSGRD---TPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEEMMQGIQ 959
Query: 863 --AKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAEL 920
+ A + L + + + + LE LR+ ++ MQ++ ++ NH E EL
Sbjct: 960 IAKEMAQQELSSQKAAYESKIKALEAELRE-ESQRKKMQEINNQKANHKIE-------EL 1011
Query: 921 VRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQN 980
+ +Q ++++ +L+ +A KQ + S + +++ L+ + +++ K ++ +QN
Sbjct: 1012 EKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQN 1071
Query: 981 Q 981
+
Sbjct: 1072 R 1072
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 263 bits (671), Expect = 1e-69
Identities = 176/481 (36%), Positives = 269/481 (55%), Gaps = 43/481 (8%)
Query: 7 GIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVG------TDKSFTYDFVF----- 55
G V+VA+R RP +E S+ + C+ + G T ++ KSFT+D+ +
Sbjct: 3 GASVKVAVRVRPFNARETSQDAK-CVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTS 61
Query: 56 --DP-CTEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV 112
DP Q++V+ ++ F+GYN + AYGQTG+GK+Y+M G Q+
Sbjct: 62 TEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQ----- 116
Query: 113 GIIPRVIQLLFKEI--DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEG 170
GI+P++ + LF + ++ + ++++VSY+EIY E + DLL P + + + +RE P G
Sbjct: 117 GIVPQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNP-KSRGSLRVREHPILG 175
Query: 171 IKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQR---KKSD 227
+ L++ V D ++ GN +RTVA+T MN SSRSHA+FTI QR + +
Sbjct: 176 PYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTG 235
Query: 228 KNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGD----DKKG 283
+ SK+ LVDLAGSER + A G RLKEG NIN+ L LG VISAL D +K
Sbjct: 236 LDSEKVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKS 295
Query: 284 SFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVN 343
F+PYRDS LT LL+++LGGNS T MIA +SPAD N EETLSTLRYADR ++I+ I+N
Sbjct: 296 DFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIIN 355
Query: 344 IDPHTAELNHLKQQVQQLQVLL------------LQAHGGTLPGSINAEPSENLQSLMEK 391
DP+ + L+++V +L+ LL L+ G++ G++ A S
Sbjct: 356 EDPNARLIRELQEEVARLRELLMAQGLSASALEGLKTEEGSVRGALPAVSSPPAPVSPSS 415
Query: 392 NQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEE-LRQHVACKLDLQKL 450
+ E E +++ + +ER+ TE++ +LN EE LR+ A +++ + L
Sbjct: 416 PTTHNGELEPSFSPNTESQIGPEEAMERLQETEKIIAELNETWEEKLRKTEALRMEREAL 475
Query: 451 V 451
+
Sbjct: 476 L 476
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 256 bits (654), Expect = 9e-68
Identities = 210/647 (32%), Positives = 315/647 (48%), Gaps = 96/647 (14%)
Query: 12 VALRCRPLVPKEISEGCQMCLSFVPGETQVVV--------------GTDKSFTYDFVFDP 57
VALR RP+ E+ EG + V + V++ +KS+ +D FD
Sbjct: 14 VALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDF 73
Query: 58 CTEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPR 117
QE V+ LI+G+ GYNATV AYG TG GKTY+M G + EP GI +
Sbjct: 74 TATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGT-----DQEP--GIYVQ 126
Query: 118 VIQLLFKEIDKKS-DFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGL 176
+ LF+ I++ S D E+ + +SYLEIYNE I DLL PS + +RED K I++ G+
Sbjct: 127 TLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSL--GYLELREDSKGVIQVAGI 184
Query: 177 TEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSF--RS 234
TE + + A + + L +GN RT TA N SSRSHA+ +++ QR + +
Sbjct: 185 TEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEVRQG 244
Query: 235 KLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLT 294
+L ++DLAGSER +T+ G R+KEG +INR LL LGN I+AL D ++ YRDSKLT
Sbjct: 245 RLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGSNKYINYRDSKLT 304
Query: 295 RLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNK---PIVNIDPHTA-- 349
RLL+DSLGGNS T+MIA +SPA S EE+ +TL YA RA+ IK + ++N+ H A
Sbjct: 305 RLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNLLNVSYHIAQY 364
Query: 350 ---------ELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSE-----------NLQSLM 389
E+ LK+++ + Q QA G G I +E + L
Sbjct: 365 TSIIADLRGEIQRLKRKIDE-QTGRGQARGRQDRGDIRHIQAEVQLHSGQGEKAGMGQLR 423
Query: 390 EKNQSLVEENEKLSRCLSKAAGQTAQM---LERIILT--EQVNEKLNAKL---EELRQHV 441
E+ S +E + R L + + ++ R +LT +EK L EE R+
Sbjct: 424 EQLASAFQEQMDVRRRLLELENRAMEVQIDTSRHLLTIAGWKHEKSRRALKWREEQRKEC 483
Query: 442 ACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACTAAAIDTAVEEEAQVETS 501
K D +K +T +DQ L VA +I V+E+ Q+
Sbjct: 484 YAKDDSEKDSDTGDDQP---------------DILEPPEVAAARESIAALVDEQKQLR-- 526
Query: 502 PETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNI 561
+ L Q +E+ L+E L R++ ++ Q + + + +
Sbjct: 527 ------------KQKLALEQRCREL--RARGRRLEETLPRRI-GSEEQREVLSLLCRVH- 570
Query: 562 KNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQ 608
ELEV N + + L+R+ ++ +L +HR + ++GQ
Sbjct: 571 ---ELEVENTEMQSHALLRDGALRHRHEAVRRLEQHRSLCDEIIQGQ 614
Score = 38.5 bits (88), Expect = 0.040
Identities = 77/401 (19%), Positives = 157/401 (39%), Gaps = 57/401 (14%)
Query: 365 LLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERII-LT 423
++Q G T +INA+ E +Q LM+ N+ +E AA QT+ ++ +T
Sbjct: 178 VIQVAGITEVSTINAK--EIMQLLMKGNRQRTQE--------PTAANQTSSRSHAVLQVT 227
Query: 424 EQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVAC 483
+ ++ L+E+RQ +DL + Q + ++ ++ + + L + C
Sbjct: 228 VRQRSRVKNILQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGN----C 283
Query: 484 TAAAIDTAVEEEAQVETSPETSRSSDAF----TTQHALHQAQMSKEVVELNNALALKEAL 539
A D + S T D+ T H + S E N L
Sbjct: 284 INALSDKGSNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRA 343
Query: 540 VRKMTQNDNQLQPIQF---QYQDNIKNLELEVINLQKEKEE------------------L 578
T+ L + + QY I +L E+ L+++ +E +
Sbjct: 344 KNIKTRVKQNLLNVSYHIAQYTSIIADLRGEIQRLKRKIDEQTGRGQARGRQDRGDIRHI 403
Query: 579 VRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQ 638
E+Q +A + + R +L + Q+ ++ L +++ ++++ T R + L
Sbjct: 404 QAEVQLHSGQGEKAGMGQLREQLASAFQEQMDVRRRLLELENRAMEVQIDTSRHL--LTI 461
Query: 639 EIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKE-------VIQLKERDRKRQY--ELLKL 689
W + R L + ++ E + + +KD + +++ E R+ L+
Sbjct: 462 AGWKHEKSRRALKWREEQRKECYAKDDSEKDSDTGDDQPDILEPPEVAAARESIAALVDE 521
Query: 690 ERNFQKQSSVLRRKTEEAAAANKRLKDAL------QKQREV 724
++ +KQ L ++ E A +RL++ L ++QREV
Sbjct: 522 QKQLRKQKLALEQRCRELRARGRRLEETLPRRIGSEEQREV 562
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 239 bits (610), Expect = 1e-62
Identities = 163/432 (37%), Positives = 246/432 (56%), Gaps = 46/432 (10%)
Query: 46 DKSFTYDFVFDPCTEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAE 105
D F +D VFD + Q EVF P+++ GYN TVLAYG TG+GKT++M G+
Sbjct: 71 DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGS---- 126
Query: 106 QENEPTVGIIPRVIQLLFKEIDK-KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIR 164
+EP G++ + L+K +D+ K + + VSYLE+YNE+I DLL S A +R
Sbjct: 127 -ADEP--GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLA---VR 180
Query: 165 EDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK 224
ED ++G+ + GLT + + + L+ GN +RT T MN+ SSRSHA+F I + Q+
Sbjct: 181 EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD 240
Query: 225 KSDK-NCSFR-SKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDK- 281
K+ N + R +K+ L+DLAGSER + A+G R EG NINR LL LGNVI+AL D K
Sbjct: 241 KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR 300
Query: 282 KGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKN--- 338
K +PYR+SKLTRLL+DSLGGN T+MIA VSP+ ++T +TL+YA+RA+ IK+
Sbjct: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360
Query: 339 KPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEE 398
++N++ H + + + Q+ ++LLL+ E L++ E+ ++ E
Sbjct: 361 SNVLNVNNHITQYVKICNE-QKAEILLLK---------------EKLKA-YEEQKAFTNE 403
Query: 399 NEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQE 458
N++ +S + + + I+ L EE+RQ + KL L++ E
Sbjct: 404 NDQAKLMISNPQEKEIERFQEIL------NCLFQNREEIRQ------EYLKLEMLLKENE 451
Query: 459 LKENVEIICNLQ 470
LK + C+ Q
Sbjct: 452 LKSFYQQQCHKQ 463
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,384,724
Number of Sequences: 37866
Number of extensions: 2116394
Number of successful extensions: 19852
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 314
Number of HSP's successfully gapped in prelim test: 1186
Number of HSP's that attempted gapping in prelim test: 9779
Number of HSP's gapped (non-prelim): 5589
length of query: 1234
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1120
effective length of database: 13,930,794
effective search space: 15602489280
effective search space used: 15602489280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.