Guide to the Human Genome
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Search of human proteins with 149274648

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
[Homo sapiens]
         (1706 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Hom...  3442   0.0  
gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sap...  2233   0.0  
gi|67782311 superkiller viralicidic activity 2-like homolog [Hom...    89   5e-17
gi|193211480 superkiller viralicidic activity 2-like 2 [Homo sap...    84   2e-15
gi|139394648 DNA polymerase theta [Homo sapiens]                       71   1e-11
gi|110556640 DNA helicase HEL308 [Homo sapiens]                        62   5e-09
gi|40217847 activating signal cointegrator 1 complex subunit 3-l...    58   9e-08
gi|76880486 activating signal cointegrator 1 complex subunit 3 i...    54   1e-06
gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote...    54   1e-06
gi|130484567 HFM1 protein [Homo sapiens]                               50   2e-05
gi|149408122 RNA helicase LGP2 [Homo sapiens]                          42   0.007
gi|49258196 syntaxin 19 [Homo sapiens]                                 39   0.056
gi|116812616 RecQ protein-like 4 [Homo sapiens]                        37   0.16 
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]      35   0.48 
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...    35   0.48 
gi|144922720 coiled-coil domain containing 15 [Homo sapiens]           35   0.82 
gi|51477718 TATA box binding protein-associated factor, RNA poly...    34   1.1  
gi|45505178 cancer antigen 1 [Homo sapiens]                            34   1.4  
gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]    34   1.4  
gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]    34   1.4  
gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens]    34   1.4  
gi|116805340 glycyl-tRNA synthetase [Homo sapiens]                     33   1.8  
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    33   1.8  
gi|14591902 RecQ protein-like [Homo sapiens]                           33   1.8  
gi|14591904 RecQ protein-like [Homo sapiens]                           33   1.8  
gi|37221175 PH domain and leucine rich repeat protein phosphatas...    33   3.1  
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    33   3.1  
gi|33946313 ninein isoform 4 [Homo sapiens]                            33   3.1  
gi|33946321 ninein isoform 5 [Homo sapiens]                            33   3.1  
gi|148536871 ninein isoform 1 [Homo sapiens]                           33   3.1  

>gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Homo
            sapiens]
          Length = 1706

 Score = 3442 bits (8924), Expect = 0.0
 Identities = 1706/1706 (100%), Positives = 1706/1706 (100%)

Query: 1    MGSKDHAVFFREMTQLILNEMPKAGYSSILNDFVESNFFVIDGDSLLVTCLGVKSFKWGQ 60
            MGSKDHAVFFREMTQLILNEMPKAGYSSILNDFVESNFFVIDGDSLLVTCLGVKSFKWGQ
Sbjct: 1    MGSKDHAVFFREMTQLILNEMPKAGYSSILNDFVESNFFVIDGDSLLVTCLGVKSFKWGQ 60

Query: 61   NLHFFYLVECYLVDLLSNGGQFTIVFFKDAEYAYFDFPELLSLRTALILHLQHNTNIDVQ 120
            NLHFFYLVECYLVDLLSNGGQFTIVFFKDAEYAYFDFPELLSLRTALILHLQHNTNIDVQ
Sbjct: 61   NLHFFYLVECYLVDLLSNGGQFTIVFFKDAEYAYFDFPELLSLRTALILHLQHNTNIDVQ 120

Query: 121  TEFSGCLSQDWKLFLEQHYPYFLIVSEEGLSDLQTYLFNFLIIHSWGMKVNVVLSSGHES 180
            TEFSGCLSQDWKLFLEQHYPYFLIVSEEGLSDLQTYLFNFLIIHSWGMKVNVVLSSGHES
Sbjct: 121  TEFSGCLSQDWKLFLEQHYPYFLIVSEEGLSDLQTYLFNFLIIHSWGMKVNVVLSSGHES 180

Query: 181  DTLRFYAYTMESTDRNQTFSKENETVIQSAYKSLIQHLEEIRVLVLATHFEHLKWNDMME 240
            DTLRFYAYTMESTDRNQTFSKENETVIQSAYKSLIQHLEEIRVLVLATHFEHLKWNDMME
Sbjct: 181  DTLRFYAYTMESTDRNQTFSKENETVIQSAYKSLIQHLEEIRVLVLATHFEHLKWNDMME 240

Query: 241  EAYQTLFLLQHLWSEGSDIQRVLCVTSCSLSLRMYHRVLVHSNCLSLQEVEDFCRLRCLC 300
            EAYQTLFLLQHLWSEGSDIQRVLCVTSCSLSLRMYHRVLVHSNCLSLQEVEDFCRLRCLC
Sbjct: 241  EAYQTLFLLQHLWSEGSDIQRVLCVTSCSLSLRMYHRVLVHSNCLSLQEVEDFCRLRCLC 300

Query: 301  VAFQLHLPLSQRACSRVITCSWIRNSDSFLKMNKWCEYFILSNLNVFGCWNLNLNHVSDL 360
            VAFQLHLPLSQRACSRVITCSWIRNSDSFLKMNKWCEYFILSNLNVFGCWNLNLNHVSDL
Sbjct: 301  VAFQLHLPLSQRACSRVITCSWIRNSDSFLKMNKWCEYFILSNLNVFGCWNLNLNHVSDL 360

Query: 361  YDEQLLKNIAFYYEFESTQEPHLNLGDSIRRDYEDLWNVVSHLVKEFNVGKSFPLRTTRR 420
            YDEQLLKNIAFYYEFESTQEPHLNLGDSIRRDYEDLWNVVSHLVKEFNVGKSFPLRTTRR
Sbjct: 361  YDEQLLKNIAFYYEFESTQEPHLNLGDSIRRDYEDLWNVVSHLVKEFNVGKSFPLRTTRR 420

Query: 421  HFLRQEKSVIQEISLEKMPSVGFIPMTSAVIDEFVGDMMKDLPILKSDDPVVPSLFKQKT 480
            HFLRQEKSVIQEISLEKMPSVGFIPMTSAVIDEFVGDMMKDLPILKSDDPVVPSLFKQKT
Sbjct: 421  HFLRQEKSVIQEISLEKMPSVGFIPMTSAVIDEFVGDMMKDLPILKSDDPVVPSLFKQKT 480

Query: 481  SDELLHWHAQRLLSDDYDRIKCHVDEQSRDPHVLDFLKKIQDYQQFYGKSLESISTKVIV 540
            SDELLHWHAQRLLSDDYDRIKCHVDEQSRDPHVLDFLKKIQDYQQFYGKSLESISTKVIV
Sbjct: 481  SDELLHWHAQRLLSDDYDRIKCHVDEQSRDPHVLDFLKKIQDYQQFYGKSLESISTKVIV 540

Query: 541  TQTTRPKEDSSGASGEILQNTKPHQITKKSKKKSFLKEDQNKAQQNDDLLFSIEEEMKNN 600
            TQTTRPKEDSSGASGEILQNTKPHQITKKSKKKSFLKEDQNKAQQNDDLLFSIEEEMKNN
Sbjct: 541  TQTTRPKEDSSGASGEILQNTKPHQITKKSKKKSFLKEDQNKAQQNDDLLFSIEEEMKNN 600

Query: 601  LHSGIRKLEDYLTSCASNSVKFGVEMLGLIACFKAWKKHCRGEGKISKDLSIAVQMMKRI 660
            LHSGIRKLEDYLTSCASNSVKFGVEMLGLIACFKAWKKHCRGEGKISKDLSIAVQMMKRI
Sbjct: 601  LHSGIRKLEDYLTSCASNSVKFGVEMLGLIACFKAWKKHCRGEGKISKDLSIAVQMMKRI 660

Query: 661  HSLLERYPEILEAEHHQYIAKCLKYLGFNDLANSLDPTLIGDDKNKKKYSIDIGPARFQL 720
            HSLLERYPEILEAEHHQYIAKCLKYLGFNDLANSLDPTLIGDDKNKKKYSIDIGPARFQL
Sbjct: 661  HSLLERYPEILEAEHHQYIAKCLKYLGFNDLANSLDPTLIGDDKNKKKYSIDIGPARFQL 720

Query: 721  QYMGHYLIRDERKDRDPRVQDFIPNAWQQELLDVVDKNESAVIVAPTSSGKTYASYYCME 780
            QYMGHYLIRDERKDRDPRVQDFIPNAWQQELLDVVDKNESAVIVAPTSSGKTYASYYCME
Sbjct: 721  QYMGHYLIRDERKDRDPRVQDFIPNAWQQELLDVVDKNESAVIVAPTSSGKTYASYYCME 780

Query: 781  KVLRESDVGVVVYVAPAKSLVGQVAATVENRFTKTLPAGRTLCGAFTRDYCHNVLNCQVL 840
            KVLRESDVGVVVYVAPAKSLVGQVAATVENRFTKTLPAGRTLCGAFTRDYCHNVLNCQVL
Sbjct: 781  KVLRESDVGVVVYVAPAKSLVGQVAATVENRFTKTLPAGRTLCGAFTRDYCHNVLNCQVL 840

Query: 841  ITVPECFEILLLAPHRQKWVERIRYVIFDEVHYLGREVGAKFWELLLVIIRCPFLVLSAT 900
            ITVPECFEILLLAPHRQKWVERIRYVIFDEVHYLGREVGAKFWELLLVIIRCPFLVLSAT
Sbjct: 841  ITVPECFEILLLAPHRQKWVERIRYVIFDEVHYLGREVGAKFWELLLVIIRCPFLVLSAT 900

Query: 901  INNPNLLTKWLQSVKQYWKQADKIMEEKCISEKQADKCLNFLQDHSYKNQSYEVRLVLYG 960
            INNPNLLTKWLQSVKQYWKQADKIMEEKCISEKQADKCLNFLQDHSYKNQSYEVRLVLYG
Sbjct: 901  INNPNLLTKWLQSVKQYWKQADKIMEEKCISEKQADKCLNFLQDHSYKNQSYEVRLVLYG 960

Query: 961  ERYNDLEKHICSVKHDDVYFDHFHPCAALTTDIIEKYGFPPDLTLTPQESIQLYDTMAQV 1020
            ERYNDLEKHICSVKHDDVYFDHFHPCAALTTDIIEKYGFPPDLTLTPQESIQLYDTMAQV
Sbjct: 961  ERYNDLEKHICSVKHDDVYFDHFHPCAALTTDIIEKYGFPPDLTLTPQESIQLYDTMAQV 1020

Query: 1021 WETWPRAQELCPEEFILFKNKIVIKKLDARKYEENLKAELTNWIKNGQVKKVKRVLKNLS 1080
            WETWPRAQELCPEEFILFKNKIVIKKLDARKYEENLKAELTNWIKNGQVKKVKRVLKNLS
Sbjct: 1021 WETWPRAQELCPEEFILFKNKIVIKKLDARKYEENLKAELTNWIKNGQVKKVKRVLKNLS 1080

Query: 1081 PDSLSSSKDMVKMFPLLVEKLRQMDKLPAIFFLFKNDDVGKRAGSVCTFLEKTETKSHPH 1140
            PDSLSSSKDMVKMFPLLVEKLRQMDKLPAIFFLFKNDDVGKRAGSVCTFLEKTETKSHPH
Sbjct: 1081 PDSLSSSKDMVKMFPLLVEKLRQMDKLPAIFFLFKNDDVGKRAGSVCTFLEKTETKSHPH 1140

Query: 1141 TECHSYVFAIDEVLEKVRKTQKRITKKNPKKAEKLERKKVYRAEYINFLENLKILEISED 1200
            TECHSYVFAIDEVLEKVRKTQKRITKKNPKKAEKLERKKVYRAEYINFLENLKILEISED
Sbjct: 1141 TECHSYVFAIDEVLEKVRKTQKRITKKNPKKAEKLERKKVYRAEYINFLENLKILEISED 1200

Query: 1201 CTYADVKALHTEITRNKDSTLERVLPRVRFTRHGKELKALAQRGIGYHHSSMYFKEKEFV 1260
            CTYADVKALHTEITRNKDSTLERVLPRVRFTRHGKELKALAQRGIGYHHSSMYFKEKEFV
Sbjct: 1201 CTYADVKALHTEITRNKDSTLERVLPRVRFTRHGKELKALAQRGIGYHHSSMYFKEKEFV 1260

Query: 1261 EILFVKGLIRVVTATETLALGIHMPCKSVVFAQDSVYLDALNYRQMSGRAGRRGQDLLGN 1320
            EILFVKGLIRVVTATETLALGIHMPCKSVVFAQDSVYLDALNYRQMSGRAGRRGQDLLGN
Sbjct: 1261 EILFVKGLIRVVTATETLALGIHMPCKSVVFAQDSVYLDALNYRQMSGRAGRRGQDLLGN 1320

Query: 1321 VYFFDIPLPKIKRLLASSVPELRGQFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHS 1380
            VYFFDIPLPKIKRLLASSVPELRGQFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHS
Sbjct: 1321 VYFFDIPLPKIKRLLASSVPELRGQFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHS 1380

Query: 1381 LLSFKRRRAMETLKLYFLFSLQLLIKEDYLNKKGNPKKFAGLASYLHGHEPSNLVFVNFL 1440
            LLSFKRRRAMETLKLYFLFSLQLLIKEDYLNKKGNPKKFAGLASYLHGHEPSNLVFVNFL
Sbjct: 1381 LLSFKRRRAMETLKLYFLFSLQLLIKEDYLNKKGNPKKFAGLASYLHGHEPSNLVFVNFL 1440

Query: 1441 KRGLFHNLCKPAWKGSQQFSQDVMEKLVLVLANLFGRKYIPAKFQNANLSFSQSKVILAE 1500
            KRGLFHNLCKPAWKGSQQFSQDVMEKLVLVLANLFGRKYIPAKFQNANLSFSQSKVILAE
Sbjct: 1441 KRGLFHNLCKPAWKGSQQFSQDVMEKLVLVLANLFGRKYIPAKFQNANLSFSQSKVILAE 1500

Query: 1501 LPEDFKAALYEYNLAVMKDFASFLLIASKSVNMKKEHQLPLSRIKFTGKECEDSQLVSHL 1560
            LPEDFKAALYEYNLAVMKDFASFLLIASKSVNMKKEHQLPLSRIKFTGKECEDSQLVSHL
Sbjct: 1501 LPEDFKAALYEYNLAVMKDFASFLLIASKSVNMKKEHQLPLSRIKFTGKECEDSQLVSHL 1560

Query: 1561 MSCKKGRVAISPFVCLSGNTDNDLLRPETINQVILRTVGVSGTQAPLLWPWKLDNRGRRM 1620
            MSCKKGRVAISPFVCLSGNTDNDLLRPETINQVILRTVGVSGTQAPLLWPWKLDNRGRRM
Sbjct: 1561 MSCKKGRVAISPFVCLSGNTDNDLLRPETINQVILRTVGVSGTQAPLLWPWKLDNRGRRM 1620

Query: 1621 PLNAYVLNFYKHNCLTRLDQKNGMRMGQLLKCLKDFAFNIQAISDSLSELCENKRDNVVL 1680
            PLNAYVLNFYKHNCLTRLDQKNGMRMGQLLKCLKDFAFNIQAISDSLSELCENKRDNVVL
Sbjct: 1621 PLNAYVLNFYKHNCLTRLDQKNGMRMGQLLKCLKDFAFNIQAISDSLSELCENKRDNVVL 1680

Query: 1681 AFKQLSQTFYEKLQEMQIQMSQNHLE 1706
            AFKQLSQTFYEKLQEMQIQMSQNHLE
Sbjct: 1681 AFKQLSQTFYEKLQEMQIQMSQNHLE 1706


>gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sapiens]
          Length = 1712

 Score = 2233 bits (5786), Expect = 0.0
 Identities = 1130/1713 (65%), Positives = 1360/1713 (79%), Gaps = 34/1713 (1%)

Query: 9    FFREMTQLILNEMPKAGYSSILNDFVESNFFVIDGDSLLVTCLGVKSFKWGQNLHFFYLV 68
            F +EM+QLILNEMPKA YSS+ NDFVES FF+IDGDSLL+TC+   SFK GQNLHFFYLV
Sbjct: 9    FSQEMSQLILNEMPKAEYSSLFNDFVESEFFLIDGDSLLITCICEISFKPGQNLHFFYLV 68

Query: 69   ECYLVDLLSNGGQFTIVFFKDAEYAYFDFPELLSLRTALILHLQHNTNIDVQTEFSGCLS 128
            E YLVDL+S GGQFTIVFFKDAEYAYF+FPELLSLRTALILHLQ NT IDV+T FS CLS
Sbjct: 69   ERYLVDLISKGGQFTIVFFKDAEYAYFNFPELLSLRTALILHLQKNTTIDVRTTFSRCLS 128

Query: 129  QDWKLFLEQHYPYFLIVSEEGLSDLQTYLFNFLIIHSWGMKVNVVLSSGHESDTLRFYAY 188
            ++W  FLE+ YPYFLIV++EGL+DLQT LFNFLIIHSW  KVNVVLSSG ESD L  YAY
Sbjct: 129  KEWGSFLEESYPYFLIVADEGLNDLQTQLFNFLIIHSWARKVNVVLSSGQESDVLCLYAY 188

Query: 189  TMESTDRNQTFSKENETVIQSAYKSLIQHLEEIRVLVLATHFEHLKWNDMMEEAYQTLFL 248
             + S  R+Q FS +N+  I+ AY +L+  LE  ++  LA  F  LKWN++ EEA++T+ L
Sbjct: 189  LLPSMYRHQIFSWKNKQNIKDAYTTLLNQLERFKLSALAPLFGSLKWNNITEEAHKTVSL 248

Query: 249  LQHLWSEGSDIQRVLCVTSCSLSLRMYHRVL---------------VHSNCLSLQEVEDF 293
            L  +W EGSDI+RV CVTSCSLSLRMYHR L               V+SNCL+LQE+ED 
Sbjct: 249  LTQVWPEGSDIRRVFCVTSCSLSLRMYHRFLGNREPSSGQETEIQQVNSNCLTLQEMEDL 308

Query: 294  CRLRCLCVAFQLHLPLSQRACSRVITCSWIRNSDSFLKMNKWCEYFILSNLNVFGCWNLN 353
            C+L CL V F LHLPLSQRAC+RVIT  W  +    L+M KWCEYFIL N++ F  WNLN
Sbjct: 309  CKLHCLTVVFLLHLPLSQRACARVITSHWAEDMKPLLQMKKWCEYFILRNIHTFEFWNLN 368

Query: 354  LNHVSDLYDEQLLKNIAFYYEFESTQEPHLNLGDSIRRDYEDLWNVVSHLVKEFNVGKSF 413
            L H+SDL DE LLKNIAFYYE E+ +  HLNLGD+I +DYE LWN VS LV++F VG+ F
Sbjct: 369  LIHLSDLNDELLLKNIAFYYENENVKGLHLNLGDTIMKDYEYLWNTVSKLVRDFEVGQPF 428

Query: 414  PLRTTRRHFLRQEKSVIQEISLEKMPSVGFIPMTSAVIDEFVGDMMKDLPILKSDDPVVP 473
            PLRTT+  FL ++ S I++ S E +P++GFIP +S V+D+F GD++KDLP LKSDDP+V 
Sbjct: 429  PLRTTKVCFLEKKPSPIKDSSNEMVPNLGFIPTSSFVVDKFAGDILKDLPFLKSDDPIVT 488

Query: 474  SLFKQKTSDELLHWHAQRLLSDDYDRIKCHVDEQSRDPHVLDFLKKIQDYQQFYGKSLES 533
            SL KQK  DEL+HWH+ + LSDDYDR +C  DE+SRDP VL  ++K   +Q+FYG SLE+
Sbjct: 489  SLVKQKEFDELVHWHSHKPLSDDYDRSRCQFDEKSRDPRVLRSVQKYHVFQRFYGNSLET 548

Query: 534  ISTKVIVTQTTRPKEDSSGASGEILQNTKPHQITKKSKKKSFLKEDQNKAQQNDDLLFSI 593
            +S+K+IVTQT + K+D SG   +    TK   I +++KK+ F +E+Q + Q+ + L FSI
Sbjct: 549  VSSKIIVTQTIKSKKDFSGPKSKKAHETKAEIIARENKKRLFAREEQKEEQKWNALSFSI 608

Query: 594  EEEMKNNLHSGIRKLEDYLTSCASNSVKFGVEMLGLIACFKAWKKHCRGE-GKISKDLSI 652
            EE++K NLHSGI+ LED+L SC S+ VK  VEM+GL AC KAWK+HCR E GK +KDLSI
Sbjct: 609  EEQLKENLHSGIKSLEDFLKSCKSSCVKLQVEMVGLTACLKAWKEHCRSEEGKTTKDLSI 668

Query: 653  AVQMMKRIHSLLERYPEILEAEHHQYIAKCLKYLGFNDLANSLDPTLIGDD----KNKKK 708
            AVQ+MKRIHSL+E+Y E+L+ +  Q IA+CLKYLGF++LA+SL P    ++    K + K
Sbjct: 669  AVQVMKRIHSLMEKYSELLQEDDRQLIARCLKYLGFDELASSLHPAQDAENDVKVKKRNK 728

Query: 709  YSIDIGPARFQLQYMGHYLIRDERKDRDPRVQDFIPNAWQQELLDVVDKNESAVIVAPTS 768
            YS+ IGPARFQLQYMGHYLIRDERKD DPRVQDFIP+ WQ+ELLDVVDKNESAVIVAPTS
Sbjct: 729  YSVGIGPARFQLQYMGHYLIRDERKDPDPRVQDFIPDTWQRELLDVVDKNESAVIVAPTS 788

Query: 769  SGKTYASYYCMEKVLRESDVGVVVYVAPAKSLVGQVAATVENRFTKTLPAGRTLCGAFTR 828
            SGKTYASYYCMEKVL+ESD GVVVYVAP K+LV QVAATV+NRFTK LP+G  LCG FTR
Sbjct: 789  SGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEVLCGVFTR 848

Query: 829  DYCHNVLNCQVLITVPECFEILLLAPHRQKWVERIRYVIFDEVHYLGREVGAKFWELLLV 888
            +Y H+ LNCQVLITVP CFEILLLAPHRQ WV++IRYVIFDEVH LG E+GA+ WE LLV
Sbjct: 849  EYRHDALNCQVLITVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGAEIWEHLLV 908

Query: 889  IIRCPFLVLSATINNPNLLTKWLQSVKQYWKQADKIMEEKCISEKQADKCLNFLQDHSYK 948
            +IRCPFL LSATI+NP  LT+WLQSVK YWKQ DKI+E    S++   +   F +D+   
Sbjct: 909  MIRCPFLALSATISNPEHLTEWLQSVKWYWKQEDKIIENNTASKRHVGRQAGFPKDYLQV 968

Query: 949  NQSYEVRLVLYGERYNDLEKHICSVKHDDVYFDHFHPCAALTTDIIEKYGFPPDLTLTPQ 1008
             QSY+VRLVLYGERYNDLEKH+CS+KH D++FDHFHPCAALTTD IE+YGFPPDLTL+P+
Sbjct: 969  KQSYKVRLVLYGERYNDLEKHVCSIKHGDIHFDHFHPCAALTTDHIERYGFPPDLTLSPR 1028

Query: 1009 ESIQLYDTMAQVWETWPRAQELCPEEFILFKNKIVIKKLDARKYEENLKAELTNWIKNGQ 1068
            ESIQLYD M Q+W++WPRAQELCPE FI F NK+VIKK+DARKYEE+LKAELT+WIKNG 
Sbjct: 1029 ESIQLYDAMFQIWKSWPRAQELCPENFIHFNNKLVIKKMDARKYEESLKAELTSWIKNGN 1088

Query: 1069 VKKVKRVLKNLSPDSLSSSKDMVKMFPLLVEKLRQMDKLPAIFFLFKNDDVGKRAGSVCT 1128
            V++ + VL+NLSP++  S ++M+ MFPLLVEKLR+M+KLPA+FFLFK   V   A SV T
Sbjct: 1089 VEQARMVLQNLSPEADLSPENMITMFPLLVEKLRKMEKLPALFFLFKLGAVENAAESVST 1148

Query: 1129 FLEKT-ETKSHPHTECHSYVFAIDEVLEKVRKT---QKRITKKNPKKAEKLERKKVYRAE 1184
            FL+K  ETK  P  +  ++V A    L KV+K+   QK I +K+ KK   +++  ++ AE
Sbjct: 1149 FLKKKQETKRPPKADKEAHVMA--NKLRKVKKSIEKQKIIDEKSQKKTRNVDQSLIHEAE 1206

Query: 1185 YINFLENL-KILEISEDCTYADVKALHTEITRNKDSTLERVLPRVRFTRHGKELKALAQR 1243
            + N ++ L K LEI +DCTYAD KA+ TE       TL++V  RV+F R G+ELKALA+R
Sbjct: 1207 HDNLVKCLEKNLEIPQDCTYADQKAVDTE-------TLQKVFGRVKFERKGEELKALAER 1259

Query: 1244 GIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVFAQDSVYLDALNY 1303
            GIGYHHS+M FKEK+ VEILF KG +RVVTAT TLALG++MPCKSVVFAQ+SVYLDALNY
Sbjct: 1260 GIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVYLDALNY 1319

Query: 1304 RQMSGRAGRRGQDLLGNVYFFDIPLPKIKRLLASSVPELRGQFPLSITLVLRLMLLASKG 1363
            RQMSGRAGRRGQDL+G+VYFFDIP PKI +L+ S+VPELRG FPLSITLVLRLMLLASKG
Sbjct: 1320 RQMSGRAGRRGQDLMGDVYFFDIPFPKIGKLIKSNVPELRGHFPLSITLVLRLMLLASKG 1379

Query: 1364 DDPEDAKAKVLSVLKHSLLSFKRRRAMETLKLYFLFSLQLLIKEDYLNKKGNPKKFAGLA 1423
            DDPEDAKAKVLSVLKHSLLSFK+ R M+ LKLYFLFSLQ L+KE YL+++GNP  FAGL 
Sbjct: 1380 DDPEDAKAKVLSVLKHSLLSFKQPRVMDMLKLYFLFSLQFLVKEGYLDQEGNPMGFAGLV 1439

Query: 1424 SYLHGHEPSNLVFVNFLKRGLFHNLCKPAWKGSQQFSQDVMEKLVLVLANLFGRKYIPAK 1483
            S+LH HEPSNLVFV+FL  GLFH+LC+P  KGS+ FSQDVMEKLVLVLA+LFGR+Y P K
Sbjct: 1440 SHLHYHEPSNLVFVSFLVNGLFHDLCQPTRKGSKHFSQDVMEKLVLVLAHLFGRRYFPPK 1499

Query: 1484 FQNANLSFSQSKVILAELPEDFKAALYEYNLAVMKDFASFLLIASKSVNMKKEHQLPLSR 1543
            FQ+A+  F QSKV L +LPEDF  AL EYN+ +M+DF +FL I SK  +M +E+QLPLS+
Sbjct: 1500 FQDAHFEFYQSKVFLDDLPEDFSDALDEYNMKIMEDFTTFLRIVSKLADMNQEYQLPLSK 1559

Query: 1544 IKFTGKECEDSQLVSHLMSCKKGRVAISPFVCLSGNTDNDLLRPETINQVILRTVGVSGT 1603
            IKFTGKECEDSQLVSHLMSCK+GRVAISPFVCLSGN D+DLLR ET N V L T+GV+ +
Sbjct: 1560 IKFTGKECEDSQLVSHLMSCKEGRVAISPFVCLSGNFDDDLLRLETPNHVTLGTIGVNRS 1619

Query: 1604 QAPLLWPWKLDNRGRRMPLNAYVLNFYKHNCLTRLDQKNGMRMGQLLKCLKDFAFNIQAI 1663
            QAP+L   K DNRGR+M LNAY L+FYKH  L  L Q N M  G     LKDFA  I++I
Sbjct: 1620 QAPVLLSQKFDNRGRKMSLNAYALDFYKHGSLIGLVQDNRMNEGDAYYLLKDFALTIKSI 1679

Query: 1664 SDSLSELCENKRDNVVLAFKQLSQTFYEKLQEM 1696
            S SL ELCEN+ DNVVLAF+QLS TF+EKL ++
Sbjct: 1680 SVSLRELCENEDDNVVLAFEQLSTTFWEKLNKV 1712


>gi|67782311 superkiller viralicidic activity 2-like homolog [Homo
            sapiens]
          Length = 1246

 Score = 88.6 bits (218), Expect = 5e-17
 Identities = 61/178 (34%), Positives = 95/178 (53%), Gaps = 26/178 (14%)

Query: 1222 ERVLPRVRFTRHGKELKALAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALG 1281
            +R LP+V        +  L  RG+G HHS +    KE VE+LF +GL++V+ ATET A+G
Sbjct: 615  DRQLPQVL------HMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMG 668

Query: 1282 IHMPCKSVVF-----AQDSVYLDAL--NYRQMSGRAGRRGQDLLGNVYFF---DIP-LPK 1330
            ++MP ++VVF        S + D L   Y QM+GRAGRRG D  G V       +P +  
Sbjct: 669  VNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMAD 728

Query: 1331 IKRLLASSVPELRGQFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHSLLSFKRRR 1388
            + R++     +L+ QF L+ T++L L+ + +          +V  ++K S   F  R+
Sbjct: 729  LHRMMMGKPSQLQSQFRLTYTMILNLLRVDA---------LRVEDMMKRSFSEFPSRK 777



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 19/179 (10%)

Query: 742 FIPNAWQQELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLRESDVGVVVYVAPAKSLV 801
           F P+ +Q++ +  +++++S  + A TS+GKT  + Y +   L +  +   +Y +P K+L 
Sbjct: 309 FEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAI--ALAQKHMTRTIYTSPIKALS 366

Query: 802 GQVAATVENRFTKTLPAGRTLCGAFTRDY-CHNVLNCQVLITVPECFEILLLAPHRQKWV 860
            Q      N F           G  T D   H   +C ++ T     EIL    +    V
Sbjct: 367 NQKFRDFRNTFGDV--------GLLTGDVQLHPEASCLIMTT-----EILRSMLYSGSDV 413

Query: 861 ER-IRYVIFDEVHYLGREVGAKFWELLLVII--RCPFLVLSATINNPNLLTKWLQSVKQ 916
            R + +VIFDEVHY+        WE +L+++      ++LSAT+ N      W+  +K+
Sbjct: 414 IRDLEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKR 472


>gi|193211480 superkiller viralicidic activity 2-like 2 [Homo sapiens]
          Length = 1042

 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 54/128 (42%), Positives = 74/128 (57%), Gaps = 10/128 (7%)

Query: 1240 LAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVF-------A 1292
            L +RGIG HH  +    KE +EILF +GLI+ + ATET A+GI+MP ++V+F        
Sbjct: 447  LLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDG 506

Query: 1293 QDSVYLDALNYRQMSGRAGRRGQDLLGNVYFF--DIPLPKI-KRLLASSVPELRGQFPLS 1349
            +D  ++ +  Y QMSGRAGRRG D  G V     +   P I K+LL  S   L   F L+
Sbjct: 507  KDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLT 566

Query: 1350 ITLVLRLM 1357
              +VL L+
Sbjct: 567  YNMVLNLL 574



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 57/190 (30%), Positives = 89/190 (46%), Gaps = 19/190 (10%)

Query: 726 YLIRDERKDRDPRVQDFIPNAWQQELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLRE 785
           YL    R  +  +   FI +A+Q+E +  VD N+S ++ A TS+GKT  + Y +   LRE
Sbjct: 122 YLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALRE 181

Query: 786 SDVGVVVYVAPAKSLVGQVAATVENRFTKTLPAGRTLCGAFTRDYCHN-VLNCQVLITVP 844
                V++ +P K+L  Q    +   F           G  T D   N   +C V+ T  
Sbjct: 182 KQ--RVIFTSPIKALSNQKYREMYEEFQDV--------GLMTGDVTINPTASCLVMTT-- 229

Query: 845 ECFEILLLAPHRQKWVER-IRYVIFDEVHYLGREVGAKFWELLLVII--RCPFLVLSATI 901
              EIL    +R   V R + +VIFDE+HY+        WE  ++++     ++ LSATI
Sbjct: 230 ---EILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATI 286

Query: 902 NNPNLLTKWL 911
            N     +W+
Sbjct: 287 PNARQFAEWI 296


>gi|139394648 DNA polymerase theta [Homo sapiens]
          Length = 2590

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 33/80 (41%), Positives = 55/80 (68%), Gaps = 5/80 (6%)

Query: 1244 GIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVFAQDSVY----LD 1299
            G+ +HH+ + F+E++ +E  F +GLIRV+ AT TL+ G+++P + V+  +  ++    LD
Sbjct: 412  GVAFHHAGLTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVII-RTPIFGGRPLD 470

Query: 1300 ALNYRQMSGRAGRRGQDLLG 1319
             L Y+QM GRAGR+G D +G
Sbjct: 471  ILTYKQMVGRAGRKGVDTVG 490



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 59/269 (21%), Positives = 108/269 (40%), Gaps = 58/269 (21%)

Query: 747 WQQE--LLDVVDKNESAVIVAPTSSGKT-YASYYCMEKVL--RESDVGVVVYVAPAK--- 798
           WQ E  LL  V + ++ V  APTS+GKT  A    +++VL  R+  + ++ +V+ AK   
Sbjct: 95  WQAECLLLGQVLEGKNLVYSAPTSAGKTLVAELLILKRVLEMRKKALFILPFVSVAKEKK 154

Query: 799 ----SLVGQVAATVENRFTKTLPAGRTLCGAFTRDYCHNVLNCQVLITVPECFEILLLAP 854
               SL  +V   V+     T P+              +  +  + +   E    L+   
Sbjct: 155 YYLQSLFQEVGIKVDGYMGSTSPS-------------RHFSSLDIAVCTIERANGLINRL 201

Query: 855 HRQKWVERIRYVIFDEVHYLGREVGAKFWELLLVII--------------------RCPF 894
             +  ++ +  V+ DE+H LG        ELLL  I                        
Sbjct: 202 IEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRKSASCQADLASSLSNAVQI 261

Query: 895 LVLSATINNPNLLTKWLQSVKQYWKQADKIMEEKCISEKQADKCLNFLQDHSYK-NQSYE 953
           + +SAT+ N  L+  WL +   +        + + +   ++ K  N + D S K  + +E
Sbjct: 262 VGMSATLPNLELVASWLNAELYH-------TDFRPVPLLESVKVGNSIYDSSMKLVREFE 314

Query: 954 VRLVLYGERYNDLEKHICSVKHDDVYFDH 982
             L + G+     E H+ S+ ++ +  +H
Sbjct: 315 PMLQVKGD-----EDHVVSLCYETICDNH 338


>gi|110556640 DNA helicase HEL308 [Homo sapiens]
          Length = 1101

 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 6/119 (5%)

Query: 1207 KALHTEITRNKDSTLERVLPRVRFTRHGK---ELKALAQRGIGYHHSSMYFKEKEFVEIL 1263
            K L  E  ++K+     V+  ++   +G     LK     G+ YHHS +   E++ +E  
Sbjct: 599  KFLSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEA 658

Query: 1264 FVKGLIRVVTATETLALGIHMPCKSVVFAQDSV---YLDALNYRQMSGRAGRRGQDLLG 1319
            +  G++ + T T TLA G+++P + V+     V   +L    Y+QM GRAGR G D +G
Sbjct: 659  YSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIG 717


>gi|40217847 activating signal cointegrator 1 complex subunit 3-like 1
            [Homo sapiens]
          Length = 2136

 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 48/168 (28%), Positives = 78/168 (46%), Gaps = 8/168 (4%)

Query: 740  QDFIP--NAWQQELLDVVDKNESAVIV-APTSSGKTYASYYCMEKVLRESDVGVVVYVAP 796
            QD  P  N  Q ++ + V  ++  V V APT SGKT  + + + ++L +S  G  VY+ P
Sbjct: 1322 QDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITP 1381

Query: 797  AKSLVGQVAATVENRFTKTLPAGRTLCGAFTRDYCHNVLNCQVLITVPECFEILLLAPHR 856
             ++L  QV      +F   L     L    T      +    ++I+ PE ++IL     +
Sbjct: 1382 MEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQ 1441

Query: 857  QKWVERIRYVIFDEVHYLGREVGAKFWELLLVIIRCPFLVLSATINNP 904
            +K V+ I   + DEVH +G E G      +L +I      +S+ I  P
Sbjct: 1442 RKNVQNINLFVVDEVHLIGGENGP-----VLEVICSRMRYISSQIERP 1484



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 35/93 (37%), Positives = 47/93 (50%), Gaps = 9/93 (9%)

Query: 1236 ELKALAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVFAQDS 1295
            ELK L   G   HH+ M   ++  VE LF    I+V+ +T TLA G+++P  +V+     
Sbjct: 773  ELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQ 832

Query: 1296 VY---------LDALNYRQMSGRAGRRGQDLLG 1319
            VY         L AL+  QM GRAGR   D  G
Sbjct: 833  VYSPEKGRWTELGALDILQMLGRAGRPQYDTKG 865



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 16/149 (10%)

Query: 755 VDKNESAVIVAPTSSGKTYASYYCM-----EKVLRESDVGV----VVYVAPAKSLVGQVA 805
           ++ +E+ ++ APT +GKT  +  CM     + +  +  + V    ++Y+AP +SLV ++ 
Sbjct: 493 LETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMV 552

Query: 806 ATVENRFTKTLPAGRTLCGAFTRDY--CHNVLNC-QVLITVPECFEILLLAPHRQKWVER 862
            +    F K L          T D+  C   ++  Q+++  PE ++I+      + + + 
Sbjct: 553 GS----FGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQL 608

Query: 863 IRYVIFDEVHYLGREVGAKFWELLLVIIR 891
           +R +I DE+H L  + G     L+   IR
Sbjct: 609 VRLIILDEIHLLHDDRGPVLEALVARAIR 637



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 9/89 (10%)

Query: 1237 LKALAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVFAQDSV 1296
            LK     G+GY H  +   E+  VE LF  G I+VV A+ +L  G+++    V+      
Sbjct: 1609 LKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQY 1668

Query: 1297 YLDAL---------NYRQMSGRAGRRGQD 1316
            Y   +         +  QM G A R  QD
Sbjct: 1669 YNGKIHAYVDYPIYDVLQMVGHANRPLQD 1697


>gi|76880486 activating signal cointegrator 1 complex subunit 3
            isoform a [Homo sapiens]
          Length = 2202

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 9/94 (9%)

Query: 1235 KELKALAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVFAQD 1294
            K+++ L   G   HH+ M  +++  VE LF  G I+V+  T TLA G+++P  +V+    
Sbjct: 769  KQVRELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGT 828

Query: 1295 SVY---------LDALNYRQMSGRAGRRGQDLLG 1319
             +Y         L  L+  Q+ GRAGR   D  G
Sbjct: 829  QIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFG 862



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 46/171 (26%), Positives = 82/171 (47%), Gaps = 21/171 (12%)

Query: 760  SAVIVAPTSSGKTYASYYCMEKVLRESDVGVVVYVAPAKSLVGQVAATVENRFTKTLPAG 819
            + ++ APT SGKT A+   + +V  +      VY+AP K+LV +     + R  + L  G
Sbjct: 1344 NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKL--G 1401

Query: 820  R---TLCGAFTRDYCHNVLNCQVLITVPECFEILLLAPHRQKWVERIRYVIFDEVHYLGR 876
            +    L G  T D   ++    +++T PE ++ +  +   + +V+++  +I DE+H LG 
Sbjct: 1402 KKVIELTGDVTPD-MKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGE 1460

Query: 877  EVGAKFWELLLVIIRCPFLV-----------LSATINNPNLLTKWLQSVKQ 916
            E G     L +++ R  F+            LS  + N   L  WL ++KQ
Sbjct: 1461 ERGP---VLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWL-NIKQ 1507



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 41/131 (31%), Positives = 60/131 (45%), Gaps = 13/131 (9%)

Query: 1222 ERVLPRVRFTRHGKELKALAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALG 1281
            ER +  +  T     LK     GIG HH+ ++ ++++ VE LFV   ++V+ AT TLA G
Sbjct: 1593 EREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWG 1652

Query: 1282 IHMPCKSVVFAQDSVYLDALNYR----------QMSGRAGRRGQDLLGN--VYFFDIPLP 1329
            ++ P   V+  + + Y D    R          QM GRAGR   D  G   +   DI   
Sbjct: 1653 VNFPAHLVII-KGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKD 1711

Query: 1330 KIKRLLASSVP 1340
              K+ L    P
Sbjct: 1712 FYKKFLYEPFP 1722



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 47/166 (28%), Positives = 76/166 (45%), Gaps = 24/166 (14%)

Query: 758 NESAVIVAPTSSGKT-YASYYCMEKVLRESDVGV-------VVYVAPAKSLVGQVAATVE 809
           NE+ +I APT +GKT  A    + ++ +    GV       +VYVAP K+L    AA + 
Sbjct: 492 NENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKAL----AAEMT 547

Query: 810 NRFTKTLPAGRTLCGAFTRDY---CHNVLNCQVLITVPECFEILLLAPHRQKWVERI-RY 865
           + F++ L     +    T D       +L  Q+L+T PE ++++         + +I R 
Sbjct: 548 DYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRL 607

Query: 866 VIFDEVHYLGREVGAKFWELLLVIIR--------CPFLVLSATINN 903
           +I DEVH L  + G     ++   +R           L LSAT+ N
Sbjct: 608 LILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPN 653


>gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein,
            partial [Homo sapiens]
          Length = 1700

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 35/93 (37%), Positives = 47/93 (50%), Gaps = 9/93 (9%)

Query: 1236 ELKALAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVFAQDS 1295
            ELK L   G   HH+ M   ++  VE LF    I+V+ +T TLA G+++P  +V+     
Sbjct: 337  ELKDLLPYGFAIHHAGMTRVDRTLVEDLFGDKHIQVLVSTATLAWGVNLPAHTVIIKGTQ 396

Query: 1296 VY---------LDALNYRQMSGRAGRRGQDLLG 1319
            VY         L AL+  QM GRAGR   D  G
Sbjct: 397  VYSPEKGRWTELGALDILQMLGRAGRPQYDTKG 429



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 46/168 (27%), Positives = 76/168 (45%), Gaps = 8/168 (4%)

Query: 740  QDFIP--NAWQQELLDVVDKNESAVIV-APTSSGKTYASYYCMEKVLRESDVGVVVYVAP 796
            QD  P  N  Q ++ + V  ++  V V APT SGKT  + + + ++L ++  G  VY+ P
Sbjct: 886  QDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITP 945

Query: 797  AKSLVGQVAATVENRFTKTLPAGRTLCGAFTRDYCHNVLNCQVLITVPECFEILLLAPHR 856
             +    QV      +F   L     L    T      +    ++I+ PE ++IL     +
Sbjct: 946  MRLWQEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQ 1005

Query: 857  QKWVERIRYVIFDEVHYLGREVGAKFWELLLVIIRCPFLVLSATINNP 904
            +K V+ I   + DEVH +G E G      +L +I      +S+ I  P
Sbjct: 1006 RKNVQNINLFVVDEVHLIGGENGP-----VLEVICSRMRYISSQIERP 1048



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 35/149 (23%), Positives = 72/149 (48%), Gaps = 16/149 (10%)

Query: 755 VDKNESAVIVAPTSSGKTYASYYCM-----EKVLRESDVGV----VVYVAPAKSLVGQVA 805
           ++ +E+ ++ APT +GKT  +  CM     + +  +  + V    ++Y+AP +SLV ++ 
Sbjct: 57  LETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMV 116

Query: 806 ATVENRFTKTLPAGRTLCGAFTRDY--CHNVLNC-QVLITVPECFEILLLAPHRQKWVER 862
            +    F K L          T D+  C   ++  Q+++  PE ++I+      + + + 
Sbjct: 117 GS----FGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKGGERTYTQL 172

Query: 863 IRYVIFDEVHYLGREVGAKFWELLLVIIR 891
           +R ++ DE+H L  + G     L+   IR
Sbjct: 173 VRLIVLDEIHLLHDDRGPVLEALVARAIR 201



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 28/90 (31%), Positives = 42/90 (46%), Gaps = 11/90 (12%)

Query: 1237 LKALAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMPCKSVVFAQDSV 1296
            LK     G+GY H  +   E+  VE LF  G I+VV A+ +L  G+++    V+   D++
Sbjct: 1173 LKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVII-MDTL 1231

Query: 1297 YLDA----------LNYRQMSGRAGRRGQD 1316
            Y +            +  QM G A R  QD
Sbjct: 1232 YYNGKIHAYVDYPIYDVLQMVGHANRPLQD 1261


>gi|130484567 HFM1 protein [Homo sapiens]
          Length = 1435

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 7/95 (7%)

Query: 1225 LPRVRFTRHGKELKALAQRGIGYHHSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHM 1284
            L +  ++    +L+ + + G  YHH+ M   +++ VE  F  G + V+  T TLA+G+++
Sbjct: 563  LQKYAYSVRDSKLRDILKDGAAYHHAGMELSDRKVVEGAFTVGDLPVLFTTSTLAMGVNL 622

Query: 1285 PCKSVVFAQDSVYLDAL-------NYRQMSGRAGR 1312
            P   VV      Y   L       +  QM GRAGR
Sbjct: 623  PAHLVVIKSTMHYAGGLFEEYSETDILQMIGRAGR 657



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 43/180 (23%), Positives = 76/180 (42%), Gaps = 21/180 (11%)

Query: 753 DVVDKNESAVIVAPTSSGKTYASYYCMEKVLRESDVG----VVVYVAPAKSLVGQVAATV 808
           D++  + + VI APT SGKT      + ++L E  +      +VY+AP K+L  Q     
Sbjct: 291 DLLYTDRNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNIKIVYMAPIKALCSQRFDDW 350

Query: 809 ENRFTKTLPAGRTLCGAFTRDYCHNVLNCQVLITVPECFEILLLAPHRQKWVERIRYVIF 868
           + +F       + L G    D    + +  +++T PE ++ +         V+ +R  + 
Sbjct: 351 KEKFGPIGLNCKELTGDTVMDDLFEIQHAHIIMTTPEKWDSMTRKWRDNSLVQLVRLFLI 410

Query: 869 DEVHYLGREVGAKFWELLL-----------------VIIRCPFLVLSATINNPNLLTKWL 911
           DEVH +  E      E+++                   I   F+ +SATI N   + +WL
Sbjct: 411 DEVHIVKDENRGPTLEVVVSRMKTVQSVSQTLKNTSTAIPMRFVAVSATIPNAEDIAEWL 470


>gi|149408122 RNA helicase LGP2 [Homo sapiens]
          Length = 678

 Score = 41.6 bits (96), Expect = 0.007
 Identities = 58/247 (23%), Positives = 104/247 (42%), Gaps = 25/247 (10%)

Query: 746 AWQQELLDVVDKNESAVIVAPTSSGKTYASYYCMEKVLRESDVGVVVYVAPAKSLVGQ-- 803
           ++Q E++    + ++ +I  PT +GKT A+ Y  ++ L   D   VV +     LV Q  
Sbjct: 5   SYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLVTQHG 64

Query: 804 --VAATVENRFTKTLPAG----RTLCGAFTRDYCHNVLNCQVLITVPECFEILLLAPHRQ 857
                 ++ R+T T  +G    R   G   R  CH++L C       E  ++ L +P  +
Sbjct: 65  EEFRRMLDGRWTVTTLSGDMGPRAGFGHLAR--CHDLLIC-----TAELLQMALTSPEEE 117

Query: 858 KWVERIRY--VIFDEVHYLGRE-----VGAKFWELLLVIIRCPFLVLSATINNPNLLTKW 910
           + VE   +  ++ DE H+  ++     + +++ EL L   +    VL  T +        
Sbjct: 118 EHVELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTASPGTGGASK 177

Query: 911 LQSVKQYWKQADKIMEEKCISEKQADKCLNFLQDHSYKN-QSYEVRLVLYGERYNDLEKH 969
           L     +  Q    ++  CI   Q   C   LQ+HS +  + Y +      + + DL K 
Sbjct: 178 LDGAINHVLQLCANLDTWCIMSPQ--NCCPQLQEHSQQPCKQYNLCHRRSQDPFGDLLKK 235

Query: 970 ICSVKHD 976
           +    HD
Sbjct: 236 LMDQIHD 242


>gi|49258196 syntaxin 19 [Homo sapiens]
          Length = 294

 Score = 38.5 bits (88), Expect = 0.056
 Identities = 30/119 (25%), Positives = 61/119 (51%), Gaps = 5/119 (4%)

Query: 556 EILQNTKPHQITKKSKKKSFLKEDQNKAQQNDDLLFSIEEEMKNNLHSGIRKLEDYLTSC 615
           E+ Q TK  ++++ S   +   E+Q    Q   +++  E   + +LH  I+KL++ + + 
Sbjct: 7   ELKQRTKEIELSRDSHVSTTETEEQGVFLQQA-VIYEREPVAERHLHE-IQKLQESINNL 64

Query: 616 ASNSVKFGVEMLGLIACFKAWKKHCRGEGKISKDLSIAVQMMKRIHSLLERYPEILEAE 674
           A N  KFG +   L+A  + +    + E  I+K++ I  + + R  SL +   E+ ++E
Sbjct: 65  ADNVQKFGQQQKSLVASMRRFSL-LKRESTITKEIKIQAEYINR--SLNDLVKEVKKSE 120


>gi|116812616 RecQ protein-like 4 [Homo sapiens]
          Length = 1208

 Score = 37.0 bits (84), Expect = 0.16
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 13/108 (12%)

Query: 1216 NKDSTLERVLPRVRFTRH--------GKELKALAQRGIGYHHSSMYFKEKEFVEILFVKG 1267
            N+    ER+   +R   H        G+  K  A+     +H+ M  +E+  V+  F++G
Sbjct: 708  NRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEA----YHAGMCSRERRRVQRAFMQG 763

Query: 1268 LIRVVTATETLALGIHMPCKSVVFAQDSVYLDALNYRQMSGRAGRRGQ 1315
             +RVV AT    +G+  P    V     +     +Y Q  GRAGR GQ
Sbjct: 764  QLRVVVATVAFGMGLDRPDVRAVL-HLGLPPSFESYVQAVGRAGRDGQ 810


>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
          Length = 4158

 Score = 35.4 bits (80), Expect = 0.48
 Identities = 33/167 (19%), Positives = 71/167 (42%), Gaps = 16/167 (9%)

Query: 919  KQADKIMEEKCISEKQADKCLNFLQ-DHSYKNQSYEVRLVLYGERYNDLEKHICSVKHDD 977
            +  + +ME+  + ++ AD+  N +Q D +      E    +  +   DL++ + ++   +
Sbjct: 2725 EDVEALMEKLAVDQESADQVRNTVQEDEATAKVKAEETQAIADDAQRDLDEALPALDAAN 2784

Query: 978  VYFDHFHPCAALTTDIIEKYGFPPDLTLTPQESIQLYDTMAQVWETWPRAQELCPEEFIL 1037
               D           +  K   PPDL +T  E+I +   +      WP A++L  +   L
Sbjct: 2785 KALDSLDKADISEIRVFTK---PPDLVMTVMEAISI---LLNAKPDWPSAKQLLGDSNFL 2838

Query: 1038 FKNKIVIKKLDARKYEENLKAELTNWIKN-----GQVKKVKRVLKNL 1079
             +    + + D    +  + A+L  +I N      +V+KV +  K++
Sbjct: 2839 KR----LLEYDKENIKPQILAKLQKYINNPDFVPEKVEKVSKACKSM 2881


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 35.4 bits (80), Expect = 0.48
 Identities = 45/211 (21%), Positives = 87/211 (41%), Gaps = 10/211 (4%)

Query: 490  QRLLSDDYDRIKCHVDEQSRDPHVLDFLKKIQDYQQFYGKSLESISTKVI-VTQTTRPKE 548
            +R L D+   +K  +D+          L K++  +      +++++ ++  + +T     
Sbjct: 944  KRKLEDECSELKKDIDDLELT------LAKVEKEKHATENKVKNLTEEMAGLDETIAKLT 997

Query: 549  DSSGASGEILQNTKPHQITKKSKKKSFLKEDQNKAQQNDDLLFSIEEEMK--NNLHSGIR 606
                A  E  Q T      ++ K  +  K      QQ DDL  S+E+E K   +L    R
Sbjct: 998  KEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKR 1057

Query: 607  KLEDYLTSCASNSVKFGVEMLGLIACFKAWKKHCRG-EGKISKDLSIAVQMMKRIHSLLE 665
            KLE  L     +++    +   L    K  +      +GKI  + ++A+Q+ K+I  L  
Sbjct: 1058 KLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQA 1117

Query: 666  RYPEILEAEHHQYIAKCLKYLGFNDLANSLD 696
            R  E+ E    +  ++       +DL+  L+
Sbjct: 1118 RIEELEEEIEAERASRAKAEKQRSDLSRELE 1148


>gi|144922720 coiled-coil domain containing 15 [Homo sapiens]
          Length = 951

 Score = 34.7 bits (78), Expect = 0.82
 Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 30/201 (14%)

Query: 414 PLRTTRRHFLRQEKSVIQEISLEKMPSVGFIPMTSAVIDEFVGDMMKDLPILKSDDPVVP 473
           P++T  +  + + +S+  E     + +  F+P   A++ +    ++KD  +L  D  +  
Sbjct: 383 PIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSI-- 440

Query: 474 SLFKQKTSDELLHWHAQRLLSDDYDRIKCHVDEQ---------SRDPHVL----DFLKKI 520
            L K +  D L     Q +L  D D +  + D+          SRD HVL    D L K 
Sbjct: 441 -LLKYQDQDFLP--RDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKY 497

Query: 521 QDYQQFYGKSLESISTKVIV---TQTTRPK--------EDSSGASGEILQNTKPHQITKK 569
           QD Q F  K    +S    V    Q   PK        +D    S +     K   I  K
Sbjct: 498 QD-QNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPK 556

Query: 570 SKKKSFLKEDQNKAQQNDDLL 590
            + + FL  DQ    ++ ++L
Sbjct: 557 CQDQDFLPRDQGVLPKDQNIL 577


>gi|51477718 TATA box binding protein-associated factor, RNA
           polymerase II, Q [Homo sapiens]
          Length = 462

 Score = 34.3 bits (77), Expect = 1.1
 Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 6/61 (9%)

Query: 550 SSGASGEILQNTKPHQITKKSKKKSFLKEDQNKAQQNDDLLFSIEE-EMKNNLHSGIRKL 608
           + G S  +++  K  QI KK KK   L + QNKAQ+  DL+  +E   +KN+  S + +L
Sbjct: 384 NEGTSSIVMEIQK--QIEKKEKK---LHKIQNKAQRQKDLIMKVENLTLKNHFQSVLEQL 438

Query: 609 E 609
           E
Sbjct: 439 E 439


>gi|45505178 cancer antigen 1 [Homo sapiens]
          Length = 641

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 44/201 (21%), Positives = 86/201 (42%), Gaps = 49/201 (24%)

Query: 1033 EEFILFKNKIVIKKLDARKYEENLKAELTNWIKNGQVKKVKRVLKNLSPDSLSSSKDMVK 1092
            EE I  K KI+++K D +K  +NL+  L N  K+ Q  +              + K+M++
Sbjct: 226  EELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESR--------------NDKEMLQ 271

Query: 1093 MFPLLVEKLRQMDKLPAIFFLFKN---DDVGKRAGSVCTFLEKTETKSHPHTECHSYVFA 1149
            +         Q  K+ A +   +     ++ ++  SV  +LE  +T S            
Sbjct: 272  L---------QFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKK---------- 312

Query: 1150 IDEVLEKVRKTQKRITKKNPKKAEKLER-KKVYRAEYINFLENLKILEISEDCTYADVKA 1208
             +E +E++++ +K + K      + L+R K+    E+++  E  + LE            
Sbjct: 313  -EEEVERLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKE---------- 361

Query: 1209 LHTEITRNKDSTLERVLPRVR 1229
             + E  +   S LE++L +VR
Sbjct: 362  -NLEERQKLKSRLEKLLTQVR 381


>gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]
          Length = 292

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 9/91 (9%)

Query: 539 IVTQTTRPKEDSSGASGEILQNTKPHQITKKSKKKS------FLKEDQNKAQQNDDLLFS 592
           I   ++    + +GASG   +  +PH+  KKS+KKS      FL+ + N +  +D    S
Sbjct: 179 ITADSSSEFSEETGASGT-RKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS 237

Query: 593 IEEEMKNNLHSGIRKLEDYL--TSCASNSVK 621
            EE  + +     RK  +    TS A+N ++
Sbjct: 238 SEESEERDTKKTKRKKREKKAHTSVANNEIQ 268


>gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]
          Length = 293

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 9/91 (9%)

Query: 539 IVTQTTRPKEDSSGASGEILQNTKPHQITKKSKKKS------FLKEDQNKAQQNDDLLFS 592
           I   ++    + +GASG   +  +PH+  KKS+KKS      FL+ + N +  +D    S
Sbjct: 180 ITADSSSEFSEETGASGT-RKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS 238

Query: 593 IEEEMKNNLHSGIRKLEDYL--TSCASNSVK 621
            EE  + +     RK  +    TS A+N ++
Sbjct: 239 SEESEERDTKKTKRKKREKKAHTSVANNEIQ 269


>gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens]
          Length = 293

 Score = 33.9 bits (76), Expect = 1.4
 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 9/91 (9%)

Query: 539 IVTQTTRPKEDSSGASGEILQNTKPHQITKKSKKKS------FLKEDQNKAQQNDDLLFS 592
           I   ++    + +GASG   +  +PH+  KKS+KKS      FL+ + N +  +D    S
Sbjct: 180 ITADSSSEFSEETGASGT-RKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS 238

Query: 593 IEEEMKNNLHSGIRKLEDYL--TSCASNSVK 621
            EE  + +     RK  +    TS A+N ++
Sbjct: 239 SEESEERDTKKTKRKKREKKAHTSVANNEIQ 269


>gi|116805340 glycyl-tRNA synthetase [Homo sapiens]
          Length = 739

 Score = 33.5 bits (75), Expect = 1.8
 Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 18/100 (18%)

Query: 415 LRTTRRHFLRQEKSVIQEISLEKMPSVGFIPMTSAVIDEFVGDMMKDLPILKSDDPVVPS 474
           ++T R+HF+++E+  I EI    +     +  TS  +D+F   M+KD+   K+ +     
Sbjct: 162 IQTWRQHFIQEEQ--ILEIDCTMLTPEPVLK-TSGHVDKFADFMVKDV---KNGE----- 210

Query: 475 LFKQKTSDELLHWHAQRLLSDDYDRIKCHVDEQSRDPHVL 514
            F+   +D LL  H Q+L+SD     KC V+++S    VL
Sbjct: 211 CFR---ADHLLKAHLQKLMSDK----KCSVEKKSEMESVL 243


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 33.5 bits (75), Expect = 1.8
 Identities = 44/211 (20%), Positives = 86/211 (40%), Gaps = 10/211 (4%)

Query: 490  QRLLSDDYDRIKCHVDEQSRDPHVLDFLKKIQDYQQFYGKSLESISTKVI-VTQTTRPKE 548
            +R L D+   +K  +D+          L K++  +      +++++ ++  + +T     
Sbjct: 944  KRKLEDECSELKKDIDDLELT------LAKVEKEKHATENKVKNLTEEMAGLDETIAKLT 997

Query: 549  DSSGASGEILQNTKPHQITKKSKKKSFLKEDQNKAQQNDDLLFSIEEEMK--NNLHSGIR 606
                A  E  Q T      ++ K  +  K      QQ DDL  S+E+E K   +L    R
Sbjct: 998  KEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKR 1057

Query: 607  KLEDYLTSCASNSVKFGVEMLGLIACFKAWKKHCRG-EGKISKDLSIAVQMMKRIHSLLE 665
            KLE  L     +++    +   L    K  +    G + KI  + ++ +Q+ K+I  L  
Sbjct: 1058 KLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQA 1117

Query: 666  RYPEILEAEHHQYIAKCLKYLGFNDLANSLD 696
            R  E+ E    +  ++       +DL+  L+
Sbjct: 1118 RIEELEEEIEAERASRAKAEKQRSDLSRELE 1148


>gi|14591902 RecQ protein-like [Homo sapiens]
          Length = 649

 Score = 33.5 bits (75), Expect = 1.8
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 5/87 (5%)

Query: 1230 FTRHGKELKALAQRGIGYH----HSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMP 1285
            F++   E   ++ + +G H    H+++  ++K  V   +    I+VV AT    +GI  P
Sbjct: 322  FSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKP 381

Query: 1286 CKSVVFAQDSVYLDALNYRQMSGRAGR 1312
                V    S+     NY Q SGRAGR
Sbjct: 382  DVRFVI-HHSMSKSMENYYQESGRAGR 407


>gi|14591904 RecQ protein-like [Homo sapiens]
          Length = 649

 Score = 33.5 bits (75), Expect = 1.8
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 5/87 (5%)

Query: 1230 FTRHGKELKALAQRGIGYH----HSSMYFKEKEFVEILFVKGLIRVVTATETLALGIHMP 1285
            F++   E   ++ + +G H    H+++  ++K  V   +    I+VV AT    +GI  P
Sbjct: 322  FSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKP 381

Query: 1286 CKSVVFAQDSVYLDALNYRQMSGRAGR 1312
                V    S+     NY Q SGRAGR
Sbjct: 382  DVRFVI-HHSMSKSMENYYQESGRAGR 407


>gi|37221175 PH domain and leucine rich repeat protein phosphatase
           [Homo sapiens]
          Length = 1205

 Score = 32.7 bits (73), Expect = 3.1
 Identities = 31/130 (23%), Positives = 58/130 (44%), Gaps = 12/130 (9%)

Query: 179 ESDTLRFY---AYTMESTDRNQTFSKENETVIQSAYKSLIQHLEEIRVLVLATHFEHLK- 234
           ++D+LRF    A  +ES     T S+E  +++Q  Y  L  +    + + L T   HLK 
Sbjct: 472 KADSLRFLNASANKLESLPP-ATLSEETNSILQELY--LTNNSLTDKCVPLLTGHPHLKI 528

Query: 235 ----WNDMMEEAYQTLFLLQHLWSEGSDIQRVLCVTSCSLSLRMYHRVLVHSNCLSL-QE 289
               +N +       +  L+ L        ++  + +  ++ R  H V+ HSNC+ +  E
Sbjct: 529 LHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHSNCIEVFPE 588

Query: 290 VEDFCRLRCL 299
           V     ++C+
Sbjct: 589 VMQLPEIKCV 598


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 32.7 bits (73), Expect = 3.1
 Identities = 40/191 (20%), Positives = 81/191 (42%), Gaps = 18/191 (9%)

Query: 490  QRLLSDDYDRIKCHVDEQSRDPHVLDFLKKIQDYQQFYGKSLESISTKV-----IVTQTT 544
            +R L D+   +K  +D+          L K++  +      +++++ ++      + + T
Sbjct: 941  KRKLEDECSELKKDIDDLELT------LAKVEKEKHATENKVKNLTEELSGLDETIAKLT 994

Query: 545  RPKEDSSGASGEILQNTKPHQITKKSKKKSFLKEDQNKAQQNDDLLFSIEEEMKN--NLH 602
            R K+    A  + L + +     ++ K  S  K      QQ +DL  S+E+E K   +L 
Sbjct: 995  REKKALQEAHQQALDDLQ----AEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLE 1050

Query: 603  SGIRKLEDYLTSCASNSVKFGVEMLGLIACFKAWK-KHCRGEGKISKDLSIAVQMMKRIH 661
               RKLE  L     + +    +   L    K    ++C+ + K+  + ++ +Q  K+I 
Sbjct: 1051 RNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIK 1110

Query: 662  SLLERYPEILE 672
             L  R  E+ E
Sbjct: 1111 ELQARIEELEE 1121


>gi|33946313 ninein isoform 4 [Homo sapiens]
          Length = 2096

 Score = 32.7 bits (73), Expect = 3.1
 Identities = 44/210 (20%), Positives = 85/210 (40%), Gaps = 40/210 (19%)

Query: 1053 EENLKAELTNWIKNGQVKKVKRVLKNLSPDSLSSSK---DMVKMFPLLVEKLRQMDKLPA 1109
            E + +    +W    Q+ +++  L  L  D   +S+   D++    +L +KL+ ++++P 
Sbjct: 1190 ENSEETRTESWELKNQISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKLKMLERIPE 1249

Query: 1110 IFFLFK--NDDVGKRAGSVCTFLEKTETKSHP----HTECHSYVFAIDEVLEKVR----- 1158
                +K   +DV +    +   L   ET+       + E  + VF + + L+K+      
Sbjct: 1250 ASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTET 1309

Query: 1159 -----KTQKRITKKNPK----------KAEKLERKKVYRAEYINFLENLKILEISEDCTY 1203
                 K+   +  +N +          K EKL+   V R +   +  +L+ LEI  D   
Sbjct: 1310 FLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLENLEIEPDGNI 1369

Query: 1204 ADVKALHTEITRNKDSTLERVLPRVRFTRH 1233
              +           + TLE  +PRVR   H
Sbjct: 1370 LQL-----------NQTLEECVPRVRSVHH 1388


>gi|33946321 ninein isoform 5 [Homo sapiens]
          Length = 2090

 Score = 32.7 bits (73), Expect = 3.1
 Identities = 44/210 (20%), Positives = 85/210 (40%), Gaps = 40/210 (19%)

Query: 1053 EENLKAELTNWIKNGQVKKVKRVLKNLSPDSLSSSK---DMVKMFPLLVEKLRQMDKLPA 1109
            E + +    +W    Q+ +++  L  L  D   +S+   D++    +L +KL+ ++++P 
Sbjct: 1184 ENSEETRTESWELKNQISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKLKMLERIPE 1243

Query: 1110 IFFLFK--NDDVGKRAGSVCTFLEKTETKSHP----HTECHSYVFAIDEVLEKVR----- 1158
                +K   +DV +    +   L   ET+       + E  + VF + + L+K+      
Sbjct: 1244 ASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTET 1303

Query: 1159 -----KTQKRITKKNPK----------KAEKLERKKVYRAEYINFLENLKILEISEDCTY 1203
                 K+   +  +N +          K EKL+   V R +   +  +L+ LEI  D   
Sbjct: 1304 FLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLENLEIEPDGNI 1363

Query: 1204 ADVKALHTEITRNKDSTLERVLPRVRFTRH 1233
              +           + TLE  +PRVR   H
Sbjct: 1364 LQL-----------NQTLEECVPRVRSVHH 1382


>gi|148536871 ninein isoform 1 [Homo sapiens]
          Length = 2046

 Score = 32.7 bits (73), Expect = 3.1
 Identities = 44/210 (20%), Positives = 85/210 (40%), Gaps = 40/210 (19%)

Query: 1053 EENLKAELTNWIKNGQVKKVKRVLKNLSPDSLSSSK---DMVKMFPLLVEKLRQMDKLPA 1109
            E + +    +W    Q+ +++  L  L  D   +S+   D++    +L +KL+ ++++P 
Sbjct: 1184 ENSEETRTESWELKNQISQLQEQLMMLCADCDRASEKKQDLLFDVSVLKKKLKMLERIPE 1243

Query: 1110 IFFLFK--NDDVGKRAGSVCTFLEKTETKSHP----HTECHSYVFAIDEVLEKVR----- 1158
                +K   +DV +    +   L   ET+       + E  + VF + + L+K+      
Sbjct: 1244 ASPKYKLLYEDVSRENDCLQEELRMMETRYDEALENNKELTAEVFRLQDELKKMEEVTET 1303

Query: 1159 -----KTQKRITKKNPK----------KAEKLERKKVYRAEYINFLENLKILEISEDCTY 1203
                 K+   +  +N +          K EKL+   V R +   +  +L+ LEI  D   
Sbjct: 1304 FLSLEKSYDEVKIENEELNVLVLRLQGKIEKLQESVVQRCDCCLWEASLENLEIEPDGNI 1363

Query: 1204 ADVKALHTEITRNKDSTLERVLPRVRFTRH 1233
              +           + TLE  +PRVR   H
Sbjct: 1364 LQL-----------NQTLEECVPRVRSVHH 1382


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,576,233
Number of Sequences: 37866
Number of extensions: 2719231
Number of successful extensions: 7280
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 7185
Number of HSP's gapped (non-prelim): 140
length of query: 1706
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1590
effective length of database: 13,855,062
effective search space: 22029548580
effective search space used: 22029548580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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