Search of human proteins with 149192871

Search of human proteins with 149192871

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149192871 OTU domain containing 3 [Homo sapiens]
         (398 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149192871 OTU domain containing 3 [Homo sapiens]                   801   0.0  
gi|157364937 OTU domain containing 6B [Homo sapiens]                   63   5e-10
gi|209977021 OTU domain containing 5 isoform b [Homo sapiens]          59   1e-08
gi|209977019 OTU domain containing 5 isoform b [Homo sapiens]          59   1e-08
gi|33457350 OTU domain containing 5 isoform a [Homo sapiens]           57   4e-08
gi|223941923 OTU domain containing 1 [Homo sapiens]                    54   2e-07
gi|46409282 OTU domain containing 6A [Homo sapiens]                    53   6e-07
gi|209977067 OTU domain containing 5 isoform c [Homo sapiens]          52   7e-07
gi|34878777 ring finger protein 20 [Homo sapiens]                      39   0.008
gi|58530840 desmoplakin isoform I [Homo sapiens]                       38   0.014
gi|11345454 Fanconi anemia, complementation group E [Homo sapiens]     38   0.018
gi|58530842 desmoplakin isoform II [Homo sapiens]                      37   0.024
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]    37   0.024
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]    37   0.024
gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]    37   0.024
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]     37   0.024
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            36   0.053
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            36   0.070
gi|197927265 RNA (guanine-9-) methyltransferase domain containin...    36   0.070
gi|197927261 RNA (guanine-9-) methyltransferase domain containin...    36   0.070
gi|22748659 RNA (guanine-9-) methyltransferase domain containing...    36   0.070
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    36   0.070
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    36   0.070
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             35   0.12 
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    35   0.16 
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]          35   0.16 
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    35   0.16 
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]      34   0.20 
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]      34   0.20 
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]      34   0.20 

>gi|149192871 OTU domain containing 3 [Homo sapiens]
          Length = 398

 Score =  801 bits (2069), Expect = 0.0
 Identities = 398/398 (100%), Positives = 398/398 (100%)

Query: 1   MSRKQAAKSRPGSGSRKAEAERKRDERAARRALAKERRNRPESGGGGGCEEEFVSFANQL 60
           MSRKQAAKSRPGSGSRKAEAERKRDERAARRALAKERRNRPESGGGGGCEEEFVSFANQL
Sbjct: 1   MSRKQAAKSRPGSGSRKAEAERKRDERAARRALAKERRNRPESGGGGGCEEEFVSFANQL 60

Query: 61  QALGLKLREVPGDGNCLFRALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVEDDIPF 120
           QALGLKLREVPGDGNCLFRALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVEDDIPF
Sbjct: 61  QALGLKLREVPGDGNCLFRALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVEDDIPF 120

Query: 121 EKHVASLAKPGTFAGNDAIVAFARNHQLNVVIHQLNAPLWQIRGTEKSSVRELHIAYRYG 180
           EKHVASLAKPGTFAGNDAIVAFARNHQLNVVIHQLNAPLWQIRGTEKSSVRELHIAYRYG
Sbjct: 121 EKHVASLAKPGTFAGNDAIVAFARNHQLNVVIHQLNAPLWQIRGTEKSSVRELHIAYRYG 180

Query: 181 EHYDSVRRINDNSEAPAHLQTDFQMLHQDESNKREKIKTKGMDSEDDLRDEVEDAVQKVC 240
           EHYDSVRRINDNSEAPAHLQTDFQMLHQDESNKREKIKTKGMDSEDDLRDEVEDAVQKVC
Sbjct: 181 EHYDSVRRINDNSEAPAHLQTDFQMLHQDESNKREKIKTKGMDSEDDLRDEVEDAVQKVC 240

Query: 241 NATGCSDFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEE 300
           NATGCSDFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEE
Sbjct: 241 NATGCSDFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEE 300

Query: 301 GGSGARIFGNQGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEE 360
           GGSGARIFGNQGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEE
Sbjct: 301 GGSGARIFGNQGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEE 360

Query: 361 RHRHKALESRGSHRDNNRSEAEANTQVTLVKTFAALNI 398
           RHRHKALESRGSHRDNNRSEAEANTQVTLVKTFAALNI
Sbjct: 361 RHRHKALESRGSHRDNNRSEAEANTQVTLVKTFAALNI 398


>gi|157364937 OTU domain containing 6B [Homo sapiens]
          Length = 323

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 52/190 (27%), Positives = 92/190 (48%), Gaps = 18/190 (9%)

Query: 16  RKAEAERKRDERAARRALAKERRNRPESGGGGGCEE-EFVSFANQLQALGLKLREVPGDG 74
           R ++A+++R+++AA     +ER    E     G    E    A  L A  L+++++P DG
Sbjct: 127 RISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDG 186

Query: 75  NCLFRALGDQLEGH--SRNHLKHRQETVDYMIKQREDFEPFVED--------DIPFEKHV 124
           +C+++A+ DQL+    +   +  R +T +YM    EDF PF+ +           F+K+ 
Sbjct: 187 HCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPEEFQKYC 246

Query: 125 ASLAKPGTFAGNDAIVAFARNHQLNVVIHQLNAPLWQIRGTEKSSVRELHI-----AYRY 179
             +     + G   + A +   Q  + I Q ++P   I   E+ S + L +     AY  
Sbjct: 247 EDIVNTAAWGGQLELRALSHILQTPIEIIQADSP--PIIVGEEYSKKPLILVYMRHAYGL 304

Query: 180 GEHYDSVRRI 189
           GEHY+SV R+
Sbjct: 305 GEHYNSVTRL 314


>gi|209977021 OTU domain containing 5 isoform b [Homo sapiens]
          Length = 566

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 42/174 (24%), Positives = 78/174 (44%), Gaps = 25/174 (14%)

Query: 40  RPESGGGGGCEEEFVSFANQLQAL--------------------GLKLREVPGDGNCLFR 79
           R E G G   E+E+ + A +++A+                    G  ++++  DG CLFR
Sbjct: 168 REEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKKGFIIKQMKEDGACLFR 227

Query: 80  ALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVEDDIPFEKHVASLAKPGTFAGNDAI 139
           A+ DQ+ G    H   R+  +DY++K  + F  +V +D  F  ++    K      +  +
Sbjct: 228 AVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTED--FTTYINRKRKNNCHGNHIEM 285

Query: 140 VAFARNHQLNVVIHQLNA-PLWQIRGTEKSSVRELHIAYRYGEHYDSVRRINDN 192
            A A  +   V ++Q +  P+    G  ++    + ++Y    HY+SV  +N N
Sbjct: 286 QAMAEMYNRPVEVYQYSTEPINTFHGIHQNEDEPIRVSYHRNIHYNSV--VNPN 337


>gi|209977019 OTU domain containing 5 isoform b [Homo sapiens]
          Length = 566

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 42/174 (24%), Positives = 78/174 (44%), Gaps = 25/174 (14%)

Query: 40  RPESGGGGGCEEEFVSFANQLQAL--------------------GLKLREVPGDGNCLFR 79
           R E G G   E+E+ + A +++A+                    G  ++++  DG CLFR
Sbjct: 168 REEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKKGFIIKQMKEDGACLFR 227

Query: 80  ALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVEDDIPFEKHVASLAKPGTFAGNDAI 139
           A+ DQ+ G    H   R+  +DY++K  + F  +V +D  F  ++    K      +  +
Sbjct: 228 AVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTED--FTTYINRKRKNNCHGNHIEM 285

Query: 140 VAFARNHQLNVVIHQLNA-PLWQIRGTEKSSVRELHIAYRYGEHYDSVRRINDN 192
            A A  +   V ++Q +  P+    G  ++    + ++Y    HY+SV  +N N
Sbjct: 286 QAMAEMYNRPVEVYQYSTEPINTFHGIHQNEDEPIRVSYHRNIHYNSV--VNPN 337


>gi|33457350 OTU domain containing 5 isoform a [Homo sapiens]
          Length = 571

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 42/179 (23%), Positives = 78/179 (43%), Gaps = 30/179 (16%)

Query: 40  RPESGGGGGCEEEFVSFANQLQAL--------------------GLKLREVPGDGNCLFR 79
           R E G G   E+E+ + A +++A+                    G  ++++  DG CLFR
Sbjct: 168 REEVGAGYNSEDEYEAAAARIEAMDPATVEQQEHWFEKALRDKKGFIIKQMKEDGACLFR 227

Query: 80  ALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVEDDIPFEKHVASLAKPGTFAGNDAI 139
           A+ DQ+ G    H   R+  +DY++K  + F  +V +D  F  ++    K      +  +
Sbjct: 228 AVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTED--FTTYINRKRKNNCHGNHIEM 285

Query: 140 VAFARNHQLNVVIHQLNA------PLWQIRGTEKSSVRELHIAYRYGEHYDSVRRINDN 192
            A A  +   V ++Q +       P+    G  ++    + ++Y    HY+SV  +N N
Sbjct: 286 QAMAEMYNRPVEVYQYSTGTSAVEPINTFHGIHQNEDEPIRVSYHRNIHYNSV--VNPN 342


>gi|223941923 OTU domain containing 1 [Homo sapiens]
          Length = 481

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 36/123 (29%), Positives = 62/123 (50%), Gaps = 13/123 (10%)

Query: 73  DGNCLFRALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVEDDIPFEKHVASLAKPGT 132
           DGNCL+RA+   + G    H + R++TV Y+    + F P +E D+   + + + A+ G 
Sbjct: 317 DGNCLYRAVSKTVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDV--GEFIIAAAQDGA 374

Query: 133 FAGNDAIVAFARNHQLNVVIH-----QLNAP----LWQIRGTEKSSVRELHIAYRYGEHY 183
           +AG   ++A  +   LNV IH     +L +P    +    G E S    + +++    HY
Sbjct: 375 WAGYPELLAMGQ--MLNVNIHLTTGGRLESPTVSTMIHYLGPEDSLRPSIWLSWLSNGHY 432

Query: 184 DSV 186
           D+V
Sbjct: 433 DAV 435


>gi|46409282 OTU domain containing 6A [Homo sapiens]
          Length = 288

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 56/205 (27%), Positives = 91/205 (44%), Gaps = 35/205 (17%)

Query: 4   KQAAKSRPGSGSRKAEAERKRDERAARRALAKERRNRPESGGGGGCEEEFVSFANQ---- 59
           K   ++RP    R ++A RKR+       +  E R R ES       E    F  +    
Sbjct: 81  KMNLENRP---PRSSKAHRKRER------MESEERERQESIFQAEMSEHLAGFKREEEEK 131

Query: 60  ----LQALGLKLREVPGDGNCLFRALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVE 115
               L A GL+++ +P DG+C++RA+ DQL   S +    R  T  YM K  ++F PF  
Sbjct: 132 LAAILGARGLEMKAIPADGHCMYRAIQDQLV-FSVSVEMLRCRTASYMKKHVDEFLPFFS 190

Query: 116 ----------DDIPFEKHVASLAKPGTFAGNDAIVAFARNHQLNVVIHQLNAPLWQIRGT 165
                     DD  F  +  ++ +   + G   + A +   +  + + Q ++P   I G 
Sbjct: 191 NPETSDSFGYDD--FMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPT-LIIGE 247

Query: 166 E--KSSVRELHIAYRY--GEHYDSV 186
           E  K  +  +++ Y Y  GEHY+SV
Sbjct: 248 EYVKKPIILVYLRYAYSLGEHYNSV 272


>gi|209977067 OTU domain containing 5 isoform c [Homo sapiens]
          Length = 349

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 5/121 (4%)

Query: 73  DGNCLFRALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVEDDIPFEKHVASLAKPGT 132
           DG CLFRA+ DQ+ G    H   R+  +DY++K  + F  +V +D  F  ++    K   
Sbjct: 4   DGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNADYFSNYVTED--FTTYINRKRKNNC 61

Query: 133 FAGNDAIVAFARNHQLNVVIHQLNA-PLWQIRGTEKSSVRELHIAYRYGEHYDSVRRIND 191
              +  + A A  +   V ++Q +  P+    G  ++    + ++Y    HY+SV  +N 
Sbjct: 62  HGNHIEMQAMAEMYNRPVEVYQYSTEPINTFHGIHQNEDEPIRVSYHRNIHYNSV--VNP 119

Query: 192 N 192
           N
Sbjct: 120 N 120


>gi|34878777 ring finger protein 20 [Homo sapiens]
          Length = 975

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 42/221 (19%), Positives = 94/221 (42%), Gaps = 37/221 (16%)

Query: 200 QTDFQMLHQDESNKREKIKTKGMDSEDDL----------RDEVEDAVQKVCNATGCS-DF 248
           Q   +++ +DE +  +K++T+ +  ED L          R E E  +     A   + + 
Sbjct: 417 QHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAANEQAGPINREM 476

Query: 249 NLIVQNLEAENYNIESAIIAVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEEGGSGARIF 308
             ++ +L+  N+ ++  ++   R  +  +++  +    SG  L Q     E+        
Sbjct: 477 RHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAEL 536

Query: 309 GNQGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEK---------KKRQE 359
                 +  +E+  +Q+S S+ ++ + N++    +++ RE++  EK         K+++ 
Sbjct: 537 ------KPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKER 590

Query: 360 ERHRHKALES-----------RGSHRDNNRSEAEANTQVTL 389
           ER + K  ES           +G H D  + EAE   Q+ +
Sbjct: 591 EREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKI 631


>gi|58530840 desmoplakin isoform I [Homo sapiens]
          Length = 2871

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 79/365 (21%), Positives = 144/365 (39%), Gaps = 49/365 (13%)

Query: 50   EEEFVSFANQLQALGL----------KLREVPGDGNCLFRALGDQLEGHSRNHLKHRQET 99
            +++   F N L+ L L          +L+    + +C  + L ++LEG  R+ LK +   
Sbjct: 1553 DQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRS-LKEQAIK 1611

Query: 100  VDYMIKQRED---FEPFVEDDIPFEKHVASLAKPGTFAGNDAIVAFARNHQLNVVIHQLN 156
            +  + +Q E     +   EDD+  ++ V      G            R  +L+  +  L 
Sbjct: 1612 ITNLTQQLEQASIVKKRSEDDLRQQRDVLD----GHLREKQRTQEELR--RLSSEVEALR 1665

Query: 157  APLWQIRGTEKSSVRELHIAYRYGEHY-----DSVRRINDNSEAPAHLQTDFQMLHQDES 211
              L Q    E+ SV++ H+     EH+     D  R +N++      LQ+  + L ++  
Sbjct: 1666 RQLLQ----EQESVKQAHLR---NEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHL 1718

Query: 212  NKREKIKTKGMDSEDDLRDEVEDAVQKVCNATGCSDFNLIVQNLEAENYNIESAIIAVLR 271
               E+++   ++ +D  R   E    K  NAT   +    +Q        ++  I  + R
Sbjct: 1719 MLEEELRNLRLEYDDLRRGRSEADSDK--NAT-ILELRSQLQISNNRTLELQGLINDLQR 1775

Query: 272  MNQGKRNNAE----ENLEPSGRVLK---QCGPLWEEGGS---GARIFGNQGLNEGRTEN- 320
              +  R   E    + LE S R+ +   QC  + +E  S     ++         R E+ 
Sbjct: 1776 ERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDE 1835

Query: 321  -NKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDNN-- 377
             N+A+++   E +  +    +    Q    QW  +  R+EE  R    E   S R+ N  
Sbjct: 1836 LNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSL 1895

Query: 378  RSEAE 382
            RSE E
Sbjct: 1896 RSEIE 1900


>gi|11345454 Fanconi anemia, complementation group E [Homo sapiens]
          Length = 536

 Score = 37.7 bits (86), Expect = 0.018
 Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 2/107 (1%)

Query: 265 AIIAVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEEGGSGARIFGNQGLNEGRTENNKAQ 324
           A+  +LR + G   + E     S R  +Q   L    G G R   +    +   E N+  
Sbjct: 135 ALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDS 194

Query: 325 ASPSEENKANKNQLAKVTNKQ--RREQQWMEKKKRQEERHRHKALES 369
             P +  K ++ + A    K+  +R + W E++  ++ER  HK+LES
Sbjct: 195 QQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLES 241


>gi|58530842 desmoplakin isoform II [Homo sapiens]
          Length = 2272

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 47/184 (25%), Positives = 73/184 (39%), Gaps = 19/184 (10%)

Query: 215  EKIKTKGMDSEDDLRDEVEDAVQKVCNATGCSDFNLIVQNLEAEN------YNIESAIIA 268
            EK + K ++   D +    D +QK   A  C   NL  Q LE+E       Y IE   + 
Sbjct: 1121 EKRRRKSVEDRFDQQKNDYDQLQK---ARQCEKENLGWQKLESEKAIKEKEYEIERLRVL 1177

Query: 269  VLRMNQGKRNNAEENLEPSGRVLK---QCGPLWEEGGS---GARIFGNQGLNEGRTEN-- 320
            +      KR    E  + S R+ +   QC  + +E  S     ++         R E+  
Sbjct: 1178 LQEEGTRKREYENELAKASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDEL 1237

Query: 321  NKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDNN--R 378
            N+A+++   E +  +    +    Q    QW  +  R+EE  R    E   S R+ N  R
Sbjct: 1238 NRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLR 1297

Query: 379  SEAE 382
            SE E
Sbjct: 1298 SEIE 1301


>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
          Length = 871

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 41/213 (19%), Positives = 95/213 (44%), Gaps = 14/213 (6%)

Query: 184 DSVRRINDNS-EAPAHLQTDFQMLHQDESNKREKIKTKGMDSE-DDLRDEVEDAVQKVCN 241
           ++V+R ND   +       DF + H+DE   R K     +     + R  +++ ++   +
Sbjct: 167 EAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLS 226

Query: 242 ATGCSDFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNA-----EENLEPSGRVLKQCGP 296
                 F+ ++ +++  +  ++    AV++M  G  N+      EE  E +G+  +    
Sbjct: 227 LMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKK 286

Query: 297 LWEEGGSGARIFGNQ----GLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWM 352
             EEG +GA +   +      +E + +  +A+   S ++K  K++      ++++E    
Sbjct: 287 --EEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE-GDGDKEEKKEDSEK 343

Query: 353 EKKKRQEERHRHKALESRGSHRDNNRSEAEANT 385
           E KK  ++R+R  + +        + SE+E+ +
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESESESES 376


>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
          Length = 872

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 41/213 (19%), Positives = 95/213 (44%), Gaps = 14/213 (6%)

Query: 184 DSVRRINDNS-EAPAHLQTDFQMLHQDESNKREKIKTKGMDSE-DDLRDEVEDAVQKVCN 241
           ++V+R ND   +       DF + H+DE   R K     +     + R  +++ ++   +
Sbjct: 167 EAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLS 226

Query: 242 ATGCSDFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNA-----EENLEPSGRVLKQCGP 296
                 F+ ++ +++  +  ++    AV++M  G  N+      EE  E +G+  +    
Sbjct: 227 LMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKK 286

Query: 297 LWEEGGSGARIFGNQ----GLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWM 352
             EEG +GA +   +      +E + +  +A+   S ++K  K++      ++++E    
Sbjct: 287 --EEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE-GDGDKEEKKEDSEK 343

Query: 353 EKKKRQEERHRHKALESRGSHRDNNRSEAEANT 385
           E KK  ++R+R  + +        + SE+E+ +
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESESESES 376


>gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]
          Length = 875

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 41/213 (19%), Positives = 95/213 (44%), Gaps = 14/213 (6%)

Query: 184 DSVRRINDNS-EAPAHLQTDFQMLHQDESNKREKIKTKGMDSE-DDLRDEVEDAVQKVCN 241
           ++V+R ND   +       DF + H+DE   R K     +     + R  +++ ++   +
Sbjct: 167 EAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLS 226

Query: 242 ATGCSDFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNA-----EENLEPSGRVLKQCGP 296
                 F+ ++ +++  +  ++    AV++M  G  N+      EE  E +G+  +    
Sbjct: 227 LMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKK 286

Query: 297 LWEEGGSGARIFGNQ----GLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWM 352
             EEG +GA +   +      +E + +  +A+   S ++K  K++      ++++E    
Sbjct: 287 --EEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE-GDGDKEEKKEDSEK 343

Query: 353 EKKKRQEERHRHKALESRGSHRDNNRSEAEANT 385
           E KK  ++R+R  + +        + SE+E+ +
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESESESES 376


>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
          Length = 876

 Score = 37.4 bits (85), Expect = 0.024
 Identities = 41/213 (19%), Positives = 95/213 (44%), Gaps = 14/213 (6%)

Query: 184 DSVRRINDNS-EAPAHLQTDFQMLHQDESNKREKIKTKGMDSE-DDLRDEVEDAVQKVCN 241
           ++V+R ND   +       DF + H+DE   R K     +     + R  +++ ++   +
Sbjct: 167 EAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLS 226

Query: 242 ATGCSDFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNA-----EENLEPSGRVLKQCGP 296
                 F+ ++ +++  +  ++    AV++M  G  N+      EE  E +G+  +    
Sbjct: 227 LMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKK 286

Query: 297 LWEEGGSGARIFGNQ----GLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWM 352
             EEG +GA +   +      +E + +  +A+   S ++K  K++      ++++E    
Sbjct: 287 --EEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE-GDGDKEEKKEDSEK 343

Query: 353 EKKKRQEERHRHKALESRGSHRDNNRSEAEANT 385
           E KK  ++R+R  + +        + SE+E+ +
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESESESES 376


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 36.2 bits (82), Expect = 0.053
 Identities = 15/64 (23%), Positives = 32/64 (50%)

Query: 317 RTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDN 376
           R +  K +    E+ K  K +  K   ++R+E++   K++R++ER + K  + +   +  
Sbjct: 50  REKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQR 109

Query: 377 NRSE 380
            R E
Sbjct: 110 GRRE 113



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 317 RTENNKAQASPSEENKANKNQLAKVTNKQRREQQWME--KKKRQEERHRHKALESRGSHR 374
           + +  + Q    E  K  + +  +  NKQRRE++  +  KKKR++ER R K    R   R
Sbjct: 101 KKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKR 160

Query: 375 DNNRSE 380
              + E
Sbjct: 161 KKRKKE 166



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 4/69 (5%)

Query: 316 GRTENNKAQASPSEE--NKANKNQLAKVTNKQRREQQWMEKKKR--QEERHRHKALESRG 371
           GR E  K +     E  NK  + +  K   K++R ++   +K+R  +E + + +  E R 
Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169

Query: 372 SHRDNNRSE 380
             R+ NR E
Sbjct: 170 KKRERNRKE 178



 Score = 30.8 bits (68), Expect = 2.2
 Identities = 12/58 (20%), Positives = 30/58 (51%)

Query: 325 ASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDNNRSEAE 382
           + P  + ++ + +  +   K++RE++   K++R ++  + +    RG  R+  R E E
Sbjct: 26  SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE 83



 Score = 30.8 bits (68), Expect = 2.2
 Identities = 15/66 (22%), Positives = 29/66 (43%)

Query: 317 RTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDN 376
           R E  K +    +E K  + +  K   K+R   +  E+K+++ E+ R +  E     R  
Sbjct: 40  RREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKK 99

Query: 377 NRSEAE 382
            + + E
Sbjct: 100 EKKKRE 105



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 12/55 (21%), Positives = 30/55 (54%)

Query: 326 SPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDNNRSE 380
           S  ++ +  + +  +   K+R+ ++  ++KK++++R R K  E +   R+  R E
Sbjct: 34  SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE 88



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 13/66 (19%), Positives = 32/66 (48%)

Query: 315 EGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHR 374
           E   EN + +    ++ +  K +  +   K+R +++   KK+++EER + +    +   +
Sbjct: 122 ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK 181

Query: 375 DNNRSE 380
           +  R E
Sbjct: 182 ERERKE 187



 Score = 28.9 bits (63), Expect = 8.5
 Identities = 16/72 (22%), Positives = 32/72 (44%), Gaps = 4/72 (5%)

Query: 311 QGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEE----RHRHKA 366
           +G  E +    + +    E  +  + +  K   ++ R ++  EKKKR+ +    R R K 
Sbjct: 58  RGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKK 117

Query: 367 LESRGSHRDNNR 378
            E +   R+N +
Sbjct: 118 KERKERERENKQ 129



 Score = 28.9 bits (63), Expect = 8.5
 Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 316 GRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRD 375
           G+ E  K +     + +  K +  +   K+RRE++  ++KK +++R R K    R   + 
Sbjct: 59  GKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRER-KQRGRRERKKK 117

Query: 376 NNRSEAE 382
             R E E
Sbjct: 118 KERKERE 124



 Score = 28.9 bits (63), Expect = 8.5
 Identities = 13/55 (23%), Positives = 29/55 (52%)

Query: 311 QGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHK 365
           +G  E + +  K +    +  +  K +  +   K+RRE++   KK+R++++ R K
Sbjct: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKK 207


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 17/71 (23%), Positives = 33/71 (46%)

Query: 317 RTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDN 376
           R E    +    E+ K  + +    T+K+ +E++  E++KR+E + R +  E R   R+ 
Sbjct: 101 RREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERER 160

Query: 377 NRSEAEANTQV 387
              +     QV
Sbjct: 161 KERKKRERKQV 171



 Score = 32.3 bits (72), Expect = 0.77
 Identities = 24/111 (21%), Positives = 42/111 (37%), Gaps = 3/111 (2%)

Query: 271 RMNQGKRNNAEENLEPSGRVLKQCGPLWEEGGSGARIFGNQGLNEGRTENNKAQASPSEE 330
           R  + +    EE  +   +  K+ G   +EG    R    +       E  K +     E
Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERE 159

Query: 331 NKANKNQLAKVTNK---QRREQQWMEKKKRQEERHRHKALESRGSHRDNNR 378
            K  K +  K   +   +R+E++  E+KKR+  R   K    R   R+  +
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 14/73 (19%), Positives = 30/73 (41%)

Query: 314 NEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSH 373
           +E + E  + +    E  K  K +  K   K  R+++  E+KKR+ E+   +  E     
Sbjct: 57  SERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRK 116

Query: 374 RDNNRSEAEANTQ 386
           +   +     + +
Sbjct: 117 KKEKKERGRTSKE 129



 Score = 28.9 bits (63), Expect = 8.5
 Identities = 24/105 (22%), Positives = 42/105 (40%), Gaps = 12/105 (11%)

Query: 276 KRNNAEENLEPSGRVLKQCGPLWEEGGSGARIFGNQGLNEGRTENNKAQASPSEENKANK 335
           +R    E  E   R  KQ G   EE              + R E  K + +  E  K  +
Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKE-----------KERKERKKRERNRKERKKERE 201

Query: 336 NQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDNNRSE 380
            +  +   K+R++++   KK+RQ++R  +   + RG      R +
Sbjct: 202 RKERRERKKERKKKE-ERKKERQKDRQTNWREKERGKRERKERKK 245


>gi|197927265 RNA (guanine-9-) methyltransferase domain containing 2
           [Homo sapiens]
          Length = 339

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 18/55 (32%), Positives = 30/55 (54%)

Query: 311 QGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHK 365
           QG+NE + E+ K +     E  + +     +  KQ  EQ+ + K+KR+E+R R K
Sbjct: 19  QGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKK 73


>gi|197927261 RNA (guanine-9-) methyltransferase domain containing 2
           [Homo sapiens]
          Length = 339

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 18/55 (32%), Positives = 30/55 (54%)

Query: 311 QGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHK 365
           QG+NE + E+ K +     E  + +     +  KQ  EQ+ + K+KR+E+R R K
Sbjct: 19  QGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKK 73


>gi|22748659 RNA (guanine-9-) methyltransferase domain containing 2
           [Homo sapiens]
          Length = 339

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 18/55 (32%), Positives = 30/55 (54%)

Query: 311 QGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHK 365
           QG+NE + E+ K +     E  + +     +  KQ  EQ+ + K+KR+E+R R K
Sbjct: 19  QGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKK 73


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 2/67 (2%)

Query: 322 KAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESR--GSHRDNNRS 379
           + +A   +E +A + +  +   ++RR Q+ ++KKK +E+    KA E++     R+  R 
Sbjct: 634 EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 693

Query: 380 EAEANTQ 386
           E E   Q
Sbjct: 694 EQERREQ 700



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 38/192 (19%), Positives = 80/192 (41%), Gaps = 20/192 (10%)

Query: 210 ESNKREKIKTKGMDSEDDLRDEVEDAVQKVCNATGCSDFNLIVQNLEAENYNIESAIIAV 269
           E  +R+K++       ++++ + E+ ++KV  A        + Q  E +   IE     +
Sbjct: 552 EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQAR-----ERVEQMKEEKKKQIEQKFAQI 606

Query: 270 LRMNQGKRNN--AEENLEP--SGRVLKQCGPLWEEGGSGARIFGNQGLNEGRTENNKAQA 325
               +  +    AEE  +   + + +++     ++     R+   Q   E R      Q 
Sbjct: 607 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK 666

Query: 326 SPSEENK-----ANKNQLAKVTNKQRREQQWMEKKKRQEE------RHRHKALESRGSHR 374
              EE +     A   +LA+   ++RREQ+  E+++R++E      R + + L  +   R
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRR 726

Query: 375 DNNRSEAEANTQ 386
           +  R +AE   Q
Sbjct: 727 EQERLQAERELQ 738



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 16/72 (22%), Positives = 35/72 (48%), Gaps = 2/72 (2%)

Query: 315 EGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHR 374
           E R +  + Q    +E +  + QLA+   ++RREQ+ ++ ++  +ER +   L+     R
Sbjct: 696 ERREQERREQERREQERREQERQLAE--QERRREQERLQAERELQEREKALRLQKEQLQR 753

Query: 375 DNNRSEAEANTQ 386
           +    + +   Q
Sbjct: 754 ELEEKKKKEEQQ 765


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 2/67 (2%)

Query: 322 KAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESR--GSHRDNNRS 379
           + +A   +E +A + +  +   ++RR Q+ ++KKK +E+    KA E++     R+  R 
Sbjct: 630 EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 689

Query: 380 EAEANTQ 386
           E E   Q
Sbjct: 690 EQERREQ 696



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 38/192 (19%), Positives = 80/192 (41%), Gaps = 20/192 (10%)

Query: 210 ESNKREKIKTKGMDSEDDLRDEVEDAVQKVCNATGCSDFNLIVQNLEAENYNIESAIIAV 269
           E  +R+K++       ++++ + E+ ++KV  A        + Q  E +   IE     +
Sbjct: 548 EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQAR-----ERVEQMKEEKKKQIEQKFAQI 602

Query: 270 LRMNQGKRNN--AEENLEP--SGRVLKQCGPLWEEGGSGARIFGNQGLNEGRTENNKAQA 325
               +  +    AEE  +   + + +++     ++     R+   Q   E R      Q 
Sbjct: 603 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK 662

Query: 326 SPSEENK-----ANKNQLAKVTNKQRREQQWMEKKKRQEE------RHRHKALESRGSHR 374
              EE +     A   +LA+   ++RREQ+  E+++R++E      R + + L  +   R
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRR 722

Query: 375 DNNRSEAEANTQ 386
           +  R +AE   Q
Sbjct: 723 EQERLQAERELQ 734



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 16/72 (22%), Positives = 35/72 (48%), Gaps = 2/72 (2%)

Query: 315 EGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHR 374
           E R +  + Q    +E +  + QLA+   ++RREQ+ ++ ++  +ER +   L+     R
Sbjct: 692 ERREQERREQERREQERREQERQLAE--QERRREQERLQAERELQEREKALRLQKEQLQR 749

Query: 375 DNNRSEAEANTQ 386
           +    + +   Q
Sbjct: 750 ELEEKKKKEEQQ 761


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 16/56 (28%), Positives = 29/56 (51%)

Query: 327 PSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDNNRSEAE 382
           PS    +     +K T KQ +E+Q  EK+++++E+ R K  + +   R+    E E
Sbjct: 706 PSPTGNSTPLGSSKETRKQEKERQKQEKERQKQEKEREKERQKQEKEREKQEKERE 761



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 19/75 (25%), Positives = 35/75 (46%), Gaps = 8/75 (10%)

Query: 317 RTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERH--------RHKALE 368
           R +  K +    +E +  + +  K   KQ +E++  EK+++++E+         R KA  
Sbjct: 728 RQKQEKERQKQEKEREKERQKQEKEREKQEKEREKQEKERQKQEKKAQGRKLSLRRKADG 787

Query: 369 SRGSHRDNNRSEAEA 383
             G H   +R  AEA
Sbjct: 788 PPGPHDGGDRPSAEA 802



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 5/65 (7%)

Query: 318 TENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDNN 377
           T N+    S  E  K  K +      KQ +E+Q  EK++ +E + + K  E +   R+  
Sbjct: 709 TGNSTPLGSSKETRKQEKER-----QKQEKERQKQEKEREKERQKQEKEREKQEKEREKQ 763

Query: 378 RSEAE 382
             E +
Sbjct: 764 EKERQ 768


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 12/119 (10%)

Query: 272 MNQGKRNNAEENLE-PSGRVLKQCGPLWEEGGSGARIFGNQGLNEGRTENNKAQAS-PSE 329
           +++GK  +  E  + P GR    C    EEG SGA  + ++   +G  +  + +   P E
Sbjct: 636 VSEGKAKSVGEAEDGPEGRGDGTC----EEGSSGAEHWQDEEREKGEKDKGRGEMERPGE 691

Query: 330 ENKANKNQLAKVTNKQRREQQWMEKKKRQE--ERHRHKALESRGSHRDNNRSEAEANTQ 386
             K    +LA+    ++R+ +  E+K+R++  ++ R++ +E  G        E E + +
Sbjct: 692 GEK----ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDRE 746



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 24/118 (20%), Positives = 44/118 (37%), Gaps = 14/118 (11%)

Query: 274  QGKRNNAEENLEPSGRVLKQCGPLWEEGGSGARIFGNQGLNEGRTENNKAQASPSEENKA 333
            +G+    EE  E  G          EE G G      +G  EG  E  + +    EE   
Sbjct: 989  EGEEEEGEEEGEEEGE--------GEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040

Query: 334  NKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDNNRSEAEANTQVTLVK 391
             + +      ++ +E +  E ++ +EE    +         +N R + E   +V+ +K
Sbjct: 1041 EEGE------EREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIK 1092


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 15/68 (22%), Positives = 39/68 (57%)

Query: 325  ASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDNNRSEAEAN 384
            ASPSE  +AN+ +LA +   ++++QQ  +++++Q+++ +     ++   +     + E  
Sbjct: 1702 ASPSEPKEANRKKLADMIASRQQQQQQQQQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQ 1761

Query: 385  TQVTLVKT 392
             Q  L+++
Sbjct: 1762 QQAALIQS 1769


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 37/193 (19%), Positives = 81/193 (41%), Gaps = 11/193 (5%)

Query: 208 QDESNKREKIKTKGMDSEDDLRDEVEDAVQKVCNATGCSDFNLIVQNLEAENYNIESAII 267
           +D+  K +K K +  D  D   +E+ED   K    T      +   + + +++N      
Sbjct: 94  KDKKKKGQKGKKQSFDDNDS--EELEDKDSK-SKKTAKPKVEMYSGSDDDDDFNKLPKKA 150

Query: 268 AVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEEGGSGARIFGNQGLNEGRTENNKAQASP 327
                   K+ +  E  E + + +K+   +   G SG          +G+ +N K +  P
Sbjct: 151 KGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGP 210

Query: 328 SEENKANKNQLA---KVTNKQRREQQWMEKKKRQEERHRHKALESR-----GSHRDNNRS 379
           + E+    +  +   K   +++ E++  E+KKR EE+ + + L+ +     G    + + 
Sbjct: 211 NIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQK 270

Query: 380 EAEANTQVTLVKT 392
           E++   +   VK+
Sbjct: 271 ESQRKFEEETVKS 283



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 299 EEGGSGARIFGNQGLNEGRTENNKAQASPSEENKANKNQL-AKVTNKQRREQQWMEKKKR 357
           ++G S A +   Q       E  + Q    EE      +L AK   ++R EQ+  E+KK 
Sbjct: 333 KKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKK- 391

Query: 358 QEERHRHKALESRGSHRDNNRSEAEANTQVTL 389
           Q+E+ R + L+  G     ++ EA A  + TL
Sbjct: 392 QKEKERKERLKKEGKLLTKSQREARARAEATL 423


>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
          Length = 1312

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 42/182 (23%), Positives = 75/182 (41%), Gaps = 13/182 (7%)

Query: 194 EAPAHLQTDFQML-HQDESNKR--EKIKTK----GMDSEDDLRDEVEDAVQKVCNATGCS 246
           + P   Q   Q+  H D S K+  EK +T+    G + EDD   E E     + N  G S
Sbjct: 291 DQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGE-EGEPSSIMNVPGES 349

Query: 247 DFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEEGGSGAR 306
                   L+ EN +   A+    ++ Q ++ + E +++    +L Q     EE     R
Sbjct: 350 TLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIK---HLLHQRQRRIEEQKEERR 406

Query: 307 IFGNQGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKA 366
               Q   E   E  K Q    +    +   L +   +++ E++   K+K+ EE+ + + 
Sbjct: 407 RVEEQQRRE--REQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSER 464

Query: 367 LE 368
           L+
Sbjct: 465 LQ 466


>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
          Length = 1303

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 42/182 (23%), Positives = 75/182 (41%), Gaps = 13/182 (7%)

Query: 194 EAPAHLQTDFQML-HQDESNKR--EKIKTK----GMDSEDDLRDEVEDAVQKVCNATGCS 246
           + P   Q   Q+  H D S K+  EK +T+    G + EDD   E E     + N  G S
Sbjct: 291 DQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGE-EGEPSSIMNVPGES 349

Query: 247 DFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEEGGSGAR 306
                   L+ EN +   A+    ++ Q ++ + E +++    +L Q     EE     R
Sbjct: 350 TLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIK---HLLHQRQRRIEEQKEERR 406

Query: 307 IFGNQGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKA 366
               Q   E   E  K Q    +    +   L +   +++ E++   K+K+ EE+ + + 
Sbjct: 407 RVEEQQRRE--REQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSER 464

Query: 367 LE 368
           L+
Sbjct: 465 LQ 466


>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
          Length = 1332

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 42/182 (23%), Positives = 75/182 (41%), Gaps = 13/182 (7%)

Query: 194 EAPAHLQTDFQML-HQDESNKR--EKIKTK----GMDSEDDLRDEVEDAVQKVCNATGCS 246
           + P   Q   Q+  H D S K+  EK +T+    G + EDD   E E     + N  G S
Sbjct: 291 DQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGE-EGEPSSIMNVPGES 349

Query: 247 DFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEEGGSGAR 306
                   L+ EN +   A+    ++ Q ++ + E +++    +L Q     EE     R
Sbjct: 350 TLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIK---HLLHQRQRRIEEQKEERR 406

Query: 307 IFGNQGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKA 366
               Q   E   E  K Q    +    +   L +   +++ E++   K+K+ EE+ + + 
Sbjct: 407 RVEEQQRRE--REQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSER 464

Query: 367 LE 368
           L+
Sbjct: 465 LQ 466


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,258,944
Number of Sequences: 37866
Number of extensions: 713708
Number of successful extensions: 4910
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 150
Number of HSP's that attempted gapping in prelim test: 3929
Number of HSP's gapped (non-prelim): 1018
length of query: 398
length of database: 18,247,518
effective HSP length: 104
effective length of query: 294
effective length of database: 14,309,454
effective search space: 4206979476
effective search space used: 4206979476
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.