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Search of human proteins with 148746206
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148746206 MAGE-like protein 2 [Homo sapiens]
(646 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148746206 MAGE-like protein 2 [Homo sapiens] 1313 0.0
gi|20143482 melanoma antigen family E, 1 [Homo sapiens] 219 5e-57
gi|29171705 melanoma antigen family D, 2 [Homo sapiens] 218 1e-56
gi|19387846 melanoma antigen family D, 2 [Homo sapiens] 218 1e-56
gi|41350320 melanoma antigen family D, 2 [Homo sapiens] 218 1e-56
gi|20162572 necdin-like 2 [Homo sapiens] 212 8e-55
gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens] 212 1e-54
gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens] 212 1e-54
gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens] 212 1e-54
gi|29826296 melanoma antigen family F, 1 [Homo sapiens] 197 3e-50
gi|89276766 trophinin isoform 5 [Homo sapiens] 193 4e-49
gi|29540551 trophinin isoform 2 [Homo sapiens] 193 4e-49
gi|29540541 trophinin isoform 2 [Homo sapiens] 193 4e-49
gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens] 187 3e-47
gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens] 187 3e-47
gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens] 187 3e-47
gi|149274614 melanoma antigen family D, 4 [Homo sapiens] 187 3e-47
gi|4505085 melanoma antigen family B, 4 [Homo sapiens] 187 3e-47
gi|29171711 melanoma antigen family B, 1 [Homo sapiens] 177 3e-44
gi|29171709 melanoma antigen family B, 1 [Homo sapiens] 177 3e-44
gi|29171707 melanoma antigen family B, 1 [Homo sapiens] 177 3e-44
gi|58530863 melanoma antigen family A, 10 [Homo sapiens] 175 1e-43
gi|10567820 melanoma antigen family A, 10 [Homo sapiens] 175 1e-43
gi|29171714 melanoma antigen family B, 3 [Homo sapiens] 172 1e-42
gi|153791873 melanoma antigen family B, 16 [Homo sapiens] 172 1e-42
gi|222418639 melanoma antigen family B, 2 [Homo sapiens] 169 1e-41
gi|73623441 melanoma antigen family B, 10 [Homo sapiens] 167 2e-41
gi|27734781 melanoma antigen family B, 18 [Homo sapiens] 166 6e-41
gi|61744473 melanoma antigen family A, 11 isoform b [Homo sapiens] 160 4e-39
gi|65507078 melanoma antigen family A, 11 isoform a [Homo sapiens] 160 4e-39
>gi|148746206 MAGE-like protein 2 [Homo sapiens]
Length = 646
Score = 1313 bits (3397), Expect = 0.0
Identities = 646/646 (100%), Positives = 646/646 (100%)
Query: 1 MEFQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQL 60
MEFQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQL
Sbjct: 1 MEFQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQL 60
Query: 61 PPQQAQASGPQAEVPTLPLQPSWQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRA 120
PPQQAQASGPQAEVPTLPLQPSWQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRA
Sbjct: 61 PPQQAQASGPQAEVPTLPLQPSWQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRA 120
Query: 121 SSIDRRGSSKERRTSSKERRAPSKDRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETF 180
SSIDRRGSSKERRTSSKERRAPSKDRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETF
Sbjct: 121 SSIDRRGSSKERRTSSKERRAPSKDRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETF 180
Query: 181 APSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMN 240
APSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMN
Sbjct: 181 APSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMN 240
Query: 241 ASKASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHTL 300
ASKASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHTL
Sbjct: 241 ASKASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHTL 300
Query: 301 AFHDWQGPRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSA 360
AFHDWQGPRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSA
Sbjct: 301 AFHDWQGPRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSA 360
Query: 361 SWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLSPLDER 420
SWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLSPLDER
Sbjct: 361 SWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLSPLDER 420
Query: 421 ANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKEIDTK 480
ANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKEIDTK
Sbjct: 421 ANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKEIDTK 480
Query: 481 NHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLDV 540
NHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLDV
Sbjct: 481 NHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLDV 540
Query: 541 RETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRFLAK 600
RETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRFLAK
Sbjct: 541 RETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRFLAK 600
Query: 601 LHKKDPQSWPFHYLEALAECEWEDTDEDEPDTGDSAHGPTSRPPPR 646
LHKKDPQSWPFHYLEALAECEWEDTDEDEPDTGDSAHGPTSRPPPR
Sbjct: 601 LHKKDPQSWPFHYLEALAECEWEDTDEDEPDTGDSAHGPTSRPPPR 646
>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
Length = 957
Score = 219 bits (559), Expect = 5e-57
Identities = 186/632 (29%), Positives = 279/632 (44%), Gaps = 107/632 (16%)
Query: 27 LPAQEAQRQAPPLVQLEQPFQGAPPSQKAV-QIQLPPQQAQASGPQAEVPTLPLQPSWQA 85
L A E + + P E+P PP+ V LPP + + S
Sbjct: 130 LAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGT-------------STSV 176
Query: 86 PPAVLQAQPGPPVAAANFP-LGSAKSLMTPSGECRASSIDRRGSSKERRTSSKERRAPSK 144
PP A GP + P G + S++ GE +S+ + S+ + P +
Sbjct: 177 PPT---AYEGPSTSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEG---LSTSVQATPDE 230
Query: 145 DRMIFAATFCAPKAVSAARAHLPAAWK-----NLPATPETFAPSSSVFPATSQFQPASLN 199
+T P A +P ++PATP PS+SV PA S Q SL
Sbjct: 231 G----PSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGE-GPSTSVLPAASDGQSISLV 285
Query: 200 AFKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMNASKASQAVPTFLMATAAAP 259
+G +++ P P A + V+ P +S + P ++T+ P
Sbjct: 286 PTRGKGSSTSVP---PTATEGLSTSVQ--------PTAGEGSSTSVPPTPGGGLSTSVPP 334
Query: 260 QATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHTLAFHDWQGPRPWENLNLSDW 319
AT E TSV P G +T P P E L+ S
Sbjct: 335 TAT----EELSTSVPPTPGEGPSTSVL---------------------PIPGEGLSTS-- 367
Query: 320 EVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSASWALSAWEGPST--SRALG 377
V D P TP EG ST + +GP +S + EGPST S +
Sbjct: 368 -VPPTASDGSDTSVPPTPG-----EGASTLVQPTAPDGPGSSVLPNPGEGPSTLFSSSAS 421
Query: 378 LSESPGSS---LP---VVVSEVASVSPGSSATQDNSKVEA-------------------- 411
+ +P LP V + V S S G + + E
Sbjct: 422 VDRNPSKCSLVLPSPRVTKASVDSDSEGPKGAEGPIEFEVLRDCESPNSISIMGLNTSRV 481
Query: 412 ----QPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLE 467
+P P+++ L+QFLLVKDQ+K P++ SEM + I++EY+++ +I+ RA LE
Sbjct: 482 AITLKPQDPMEQNVAELLQFLLVKDQSKYPIRESEMREYIVKEYRNQFPEILRRAAAHLE 541
Query: 468 CAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVRED 527
C F ++L+E+D + H YI++NKLG + + PK GLLM++L IF+ GN +E
Sbjct: 542 CIFRFELRELDPEAHTYILLNKLGPVPFEGLEESPNGPKMGLLMMILGQIFLNGNQAKEA 601
Query: 528 LIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFL 587
I+ L+++G+ +FGN K+L++ FV Q+YL+YR + +P EYEF WGPR+ L
Sbjct: 602 EIWEMLWRMGVQRERRLSIFGNPKRLLSVEFVWQRYLDYRPVTDCKPVEYEFFWGPRSHL 661
Query: 588 ETSKMLVLRFLAKLHKKDPQSWPFHYLEALAE 619
ET+KM +L+F+AK++ KDP WP Y EAL E
Sbjct: 662 ETTKMKILKFMAKIYNKDPMDWPEKYNEALEE 693
Score = 152 bits (384), Expect = 9e-37
Identities = 94/273 (34%), Positives = 141/273 (51%), Gaps = 20/273 (7%)
Query: 368 EGPSTSRALGLSESPGSSLPVVVSEVASV-SPGSSATQDNSKV--EAQPLSPLDERANAL 424
E + + A G P P A V SP S + +SK + P S L+ +A L
Sbjct: 693 EDAARAFAEGWQALPHFRRPFFEEAAAEVPSPDSEVSSYSSKYAPHSWPESRLESKARKL 752
Query: 425 VQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKEIDTKNHAY 484
VQ L+ D K+P+ + ++ I RE D++NRA L +G +L +D +NH+Y
Sbjct: 753 VQLFLLMDSTKLPIPKKGILYYIGRECSKVFPDLLNRAARTLNHVYGTELVVLDPRNHSY 812
Query: 485 IIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETN 544
+ N+ + +RP LM VLS IF+ GN RE ++ FL LG+
Sbjct: 813 TLYNRREMEETEEIVDSPNRPGNNFLMQVLSFIFIMGNHARESAVWAFLRGLGVQA---- 868
Query: 545 GLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKK 604
K +IT ++ Q+Y++ R+P ++P +YEF+WGPRA LETSKM LR++A++H+K
Sbjct: 869 ----GRKHVITCRYLSQRYIDSLRVPDSDPVQYEFVWGPRARLETSKMKALRYVARIHRK 924
Query: 605 DPQSWPFHYLEALAECEWEDTDEDEPDTGDSAH 637
+PQ WP Y EA+ EDE + D H
Sbjct: 925 EPQDWPQQYREAM---------EDEANRADVGH 948
Score = 36.2 bits (82), Expect = 0.096
Identities = 24/60 (40%), Positives = 31/60 (51%)
Query: 338 RGLSGWEGPSTSRILSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVS 397
+GL EGPSTS + + EGPS + E S S +SE PG+S+ SE S S
Sbjct: 56 QGLCASEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPTISEGPGTSVLPTPSEGLSTS 115
Score = 35.4 bits (80), Expect = 0.16
Identities = 24/54 (44%), Positives = 30/54 (55%)
Query: 344 EGPSTSRILSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVS 397
EG STS + +G S L+A EG +TSR SE P +S+P SEV S S
Sbjct: 110 EGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTS 163
Score = 30.0 bits (66), Expect = 6.9
Identities = 23/64 (35%), Positives = 31/64 (48%)
Query: 344 EGPSTSRILSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSAT 403
+G TS L+ EG + S ++ E PSTS SE P +SLP E S S +A
Sbjct: 122 KGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAY 181
Query: 404 QDNS 407
+ S
Sbjct: 182 EGPS 185
>gi|29171705 melanoma antigen family D, 2 [Homo sapiens]
Length = 606
Score = 218 bits (555), Expect = 1e-56
Identities = 159/449 (35%), Positives = 223/449 (49%), Gaps = 48/449 (10%)
Query: 176 TPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSL--PYALQDPFACVEALPAVPW 233
TPE ++ +T+Q + A + S A++T K P A+ P V
Sbjct: 72 TPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMP---ATETKKVSH 128
Query: 234 VPQPNMNA-SKASQAVPTFLMATAAAPQ-ATATTQEASKTSVEPPRRSGKATRKKKHLEA 291
V +N ++ ++A P+ A P+ A A +QE T P+ K RK KHL+
Sbjct: 129 VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTR---PKVKAKKARKVKHLDG 185
Query: 292 QEDSRGHTLAFHDWQGPRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRI 351
+ED QS Q SG + L SR
Sbjct: 186 EEDGSSD-----------------------QS--QASGTTGGRRVSKALMASMARRASR- 219
Query: 352 LSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEA 411
GP A WA A S +R + SL + ++ Q + + EA
Sbjct: 220 -----GPIAFWARRA----SRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA 270
Query: 412 QP---LSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLEC 468
P ++ L RAN LV++LL KDQ K+P++RS+M+K I++EY D +II RA LE
Sbjct: 271 PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEK 330
Query: 469 AFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDL 528
FG QLKEID +H YI+++ L ++ + D PK GLLMV+LS+IFM GN E +
Sbjct: 331 VFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAV 390
Query: 529 IFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLE 588
I+ L KLGL + LFG+ KKLIT+ FV+QKYL+Y R+P + P EYEF WG R++ E
Sbjct: 391 IWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYE 450
Query: 589 TSKMLVLRFLAKLHKKDPQSWPFHYLEAL 617
TSKM VL+F K+ KKDP+ W Y EA+
Sbjct: 451 TSKMKVLKFACKVQKKDPKEWAAQYREAM 479
>gi|19387846 melanoma antigen family D, 2 [Homo sapiens]
Length = 606
Score = 218 bits (555), Expect = 1e-56
Identities = 159/449 (35%), Positives = 223/449 (49%), Gaps = 48/449 (10%)
Query: 176 TPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSL--PYALQDPFACVEALPAVPW 233
TPE ++ +T+Q + A + S A++T K P A+ P V
Sbjct: 72 TPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMP---ATETKKVSH 128
Query: 234 VPQPNMNA-SKASQAVPTFLMATAAAPQ-ATATTQEASKTSVEPPRRSGKATRKKKHLEA 291
V +N ++ ++A P+ A P+ A A +QE T P+ K RK KHL+
Sbjct: 129 VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTR---PKVKAKKARKVKHLDG 185
Query: 292 QEDSRGHTLAFHDWQGPRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRI 351
+ED QS Q SG + L SR
Sbjct: 186 EEDGSSD-----------------------QS--QASGTTGGRRVSKALMASMARRASR- 219
Query: 352 LSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEA 411
GP A WA A S +R + SL + ++ Q + + EA
Sbjct: 220 -----GPIAFWARRA----SRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA 270
Query: 412 QP---LSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLEC 468
P ++ L RAN LV++LL KDQ K+P++RS+M+K I++EY D +II RA LE
Sbjct: 271 PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEK 330
Query: 469 AFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDL 528
FG QLKEID +H YI+++ L ++ + D PK GLLMV+LS+IFM GN E +
Sbjct: 331 VFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAV 390
Query: 529 IFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLE 588
I+ L KLGL + LFG+ KKLIT+ FV+QKYL+Y R+P + P EYEF WG R++ E
Sbjct: 391 IWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYE 450
Query: 589 TSKMLVLRFLAKLHKKDPQSWPFHYLEAL 617
TSKM VL+F K+ KKDP+ W Y EA+
Sbjct: 451 TSKMKVLKFACKVQKKDPKEWAAQYREAM 479
>gi|41350320 melanoma antigen family D, 2 [Homo sapiens]
Length = 606
Score = 218 bits (555), Expect = 1e-56
Identities = 159/449 (35%), Positives = 223/449 (49%), Gaps = 48/449 (10%)
Query: 176 TPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSL--PYALQDPFACVEALPAVPW 233
TPE ++ +T+Q + A + S A++T K P A+ P V
Sbjct: 72 TPEAREAPATQASSTTQLTDTQVLAAENKSLAADTKKQNADPQAVTMP---ATETKKVSH 128
Query: 234 VPQPNMNA-SKASQAVPTFLMATAAAPQ-ATATTQEASKTSVEPPRRSGKATRKKKHLEA 291
V +N ++ ++A P+ A P+ A A +QE T P+ K RK KHL+
Sbjct: 129 VADTKVNTKAQETEAAPSQAPADEPEPESAAAQSQENQDTR---PKVKAKKARKVKHLDG 185
Query: 292 QEDSRGHTLAFHDWQGPRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRI 351
+ED QS Q SG + L SR
Sbjct: 186 EEDGSSD-----------------------QS--QASGTTGGRRVSKALMASMARRASR- 219
Query: 352 LSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEA 411
GP A WA A S +R + SL + ++ Q + + EA
Sbjct: 220 -----GPIAFWARRA----SRTRLAAWARRALLSLRSPKARRGKARRRAAKLQSSQEPEA 270
Query: 412 QP---LSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLEC 468
P ++ L RAN LV++LL KDQ K+P++RS+M+K I++EY D +II RA LE
Sbjct: 271 PPPRDVALLQGRANDLVKYLLAKDQTKIPIKRSDMLKDIIKEYTDVYPEIIERAGYSLEK 330
Query: 469 AFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDL 528
FG QLKEID +H YI+++ L ++ + D PK GLLMV+LS+IFM GN E +
Sbjct: 331 VFGIQLKEIDKNDHLYILLSTLEPTDAGILGTTKDSPKLGLLMVLLSIIFMNGNRSSEAV 390
Query: 529 IFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLE 588
I+ L KLGL + LFG+ KKLIT+ FV+QKYL+Y R+P + P EYEF WG R++ E
Sbjct: 391 IWEVLRKLGLRPGIHHSLFGDVKKLITDEFVKQKYLDYARVPNSNPPEYEFFWGLRSYYE 450
Query: 589 TSKMLVLRFLAKLHKKDPQSWPFHYLEAL 617
TSKM VL+F K+ KKDP+ W Y EA+
Sbjct: 451 TSKMKVLKFACKVQKKDPKEWAAQYREAM 479
>gi|20162572 necdin-like 2 [Homo sapiens]
Length = 304
Score = 212 bits (540), Expect = 8e-55
Identities = 122/293 (41%), Positives = 171/293 (58%), Gaps = 23/293 (7%)
Query: 330 DWEHPNTPRGLSGWEGPSTSRILSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVV 389
DW H P E R G+ A E PSTSR G S+ P
Sbjct: 20 DWSHSGNPGASRAGEDARVLR--DGF----------AEEAPSTSRGPGGSQGSQGPSP-- 65
Query: 390 VSEVASVSPGSSATQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILR 449
G+ Q V + L+ + + LVQFLL+KDQ K+P++R++++K ++
Sbjct: 66 --------QGARRAQAAPAVGPRSQKQLELKVSELVQFLLIKDQKKIPIKRADILKHVIG 117
Query: 450 EYKDECLDIINRANNKLECAFGYQLKEIDTKNHAYIIINKLG-YHTGNLVASYLDRPKFG 508
+YKD D+ RA +L+ FGY+L E++ K++ YI+IN L + P G
Sbjct: 118 DYKDIFPDLFKRAAERLQYVFGYKLVELEPKSNTYILINTLEPVEEDAEMRGDQGTPTTG 177
Query: 509 LLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRR 568
LLM+VL LIFMKGN ++E ++FL +LG+ + + +FG+ KKLITE FVRQ+YLEYRR
Sbjct: 178 LLMIVLGLIFMKGNTIKETEAWDFLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEYRR 237
Query: 569 IPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECE 621
IP+T+P +YEF WGPR LETSKM VL+F+AK+H +DP+ WP Y EALA+ E
Sbjct: 238 IPHTDPVDYEFQWGPRTNLETSKMKVLKFVAKVHNQDPKDWPAQYCEALADEE 290
>gi|52632381 melanoma antigen family D, 1 isoform a [Homo sapiens]
Length = 834
Score = 212 bits (539), Expect = 1e-54
Identities = 126/324 (38%), Positives = 180/324 (55%), Gaps = 22/324 (6%)
Query: 305 WQGPRPWEN----LNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPS- 359
W GP W N N W+ Q W+ P +G W P + W P+
Sbjct: 418 WPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTD 477
Query: 360 ----ASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLS 415
W + W P + L P +L SP S A+Q+ + + ++
Sbjct: 478 WPLPPDWIPADWPIPPDWQNL----RPSPNL--------RPSPNSRASQNPGAAQPRDVA 525
Query: 416 PLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLK 475
L ERAN LV++L++KD KVP++RSEM++ I+REY D +II RA LE FG QLK
Sbjct: 526 LLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLK 585
Query: 476 EIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFK 535
EID + H YI+I+ G ++ + D PK GLL+V+L +IFM GN E +++ L K
Sbjct: 586 EIDKEEHLYILISTPESLAG-ILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRK 644
Query: 536 LGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVL 595
+GL + L G+ +KL+T FV+QKYL+YRR+P + P EYEFLWG R++ ETSKM VL
Sbjct: 645 MGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVL 704
Query: 596 RFLAKLHKKDPQSWPFHYLEALAE 619
RF+A++ K+DP+ W ++EA E
Sbjct: 705 RFIAEVQKRDPRDWTAQFMEAADE 728
Score = 35.8 bits (81), Expect = 0.13
Identities = 76/363 (20%), Positives = 116/363 (31%), Gaps = 46/363 (12%)
Query: 37 PPLVQLEQPFQ---------GAPPSQKAVQIQLPPQQAQASGPQAEVPTLPLQPSWQAPP 87
PP QL P GA P+ ++ Q ++ P P+ QA
Sbjct: 46 PPYSQLRDPPAVLSCYCTPLGASPAPAEASVEDSALLMQTLMEAIQISEAP--PTNQATA 103
Query: 88 AVLQAQPGPPVAAANFPLGSAKSLMTPSGECRASSIDRRGSSKERRTSSKERRAP---SK 144
A PP A + + + P + + +G + S ++
Sbjct: 104 AASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNAKDVPNTQ 163
Query: 145 DRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETFAPSSSVF----PATSQFQPASLNA 200
+ F + PK +AA AA T E A S + AT++ P +
Sbjct: 164 PKAAFKSQNATPKGPNAAYDFSQAA-----TTGELAANKSEMAFKAQNATTKVGPNATYN 218
Query: 201 FKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMNASKASQAV--------PTFL 252
F A++ S P + PF P N ++A A P
Sbjct: 219 FSQSLNANDLANSRP---KTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADIETDPGIS 275
Query: 253 MATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHT----LAFHDWQG- 307
A Q +A +A R GK TRK +L +E+S G LA W+
Sbjct: 276 EPDGATAQTSADGSQAQNLESRTIIR-GKRTRKINNLNVEENSSGDQRRAPLAAGTWRSA 334
Query: 308 PRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSASWALSAW 367
P P N Q W++P SGW+ + + + P A AW
Sbjct: 335 PVPVTTQNPPGAPPNVLWQTPLAWQNP------SGWQNQTARQTPPARQSPPARQTPPAW 388
Query: 368 EGP 370
+ P
Sbjct: 389 QNP 391
>gi|52632379 melanoma antigen family D, 1 isoform b [Homo sapiens]
Length = 778
Score = 212 bits (539), Expect = 1e-54
Identities = 126/324 (38%), Positives = 180/324 (55%), Gaps = 22/324 (6%)
Query: 305 WQGPRPWEN----LNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPS- 359
W GP W N N W+ Q W+ P +G W P + W P+
Sbjct: 362 WPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTD 421
Query: 360 ----ASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLS 415
W + W P + L P +L SP S A+Q+ + + ++
Sbjct: 422 WPLPPDWIPADWPIPPDWQNL----RPSPNL--------RPSPNSRASQNPGAAQPRDVA 469
Query: 416 PLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLK 475
L ERAN LV++L++KD KVP++RSEM++ I+REY D +II RA LE FG QLK
Sbjct: 470 LLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLK 529
Query: 476 EIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFK 535
EID + H YI+I+ G ++ + D PK GLL+V+L +IFM GN E +++ L K
Sbjct: 530 EIDKEEHLYILISTPESLAG-ILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRK 588
Query: 536 LGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVL 595
+GL + L G+ +KL+T FV+QKYL+YRR+P + P EYEFLWG R++ ETSKM VL
Sbjct: 589 MGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVL 648
Query: 596 RFLAKLHKKDPQSWPFHYLEALAE 619
RF+A++ K+DP+ W ++EA E
Sbjct: 649 RFIAEVQKRDPRDWTAQFMEAADE 672
Score = 34.7 bits (78), Expect = 0.28
Identities = 66/310 (21%), Positives = 101/310 (32%), Gaps = 35/310 (11%)
Query: 81 PSWQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRASSIDRRGSSKERRTSSKERR 140
P+ QA A PP A + + + P + + +G + S
Sbjct: 41 PTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNA 100
Query: 141 AP---SKDRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETFAPSSSVF----PATSQF 193
++ + F + PK +AA AA T E A S + AT++
Sbjct: 101 KDVPNTQPKAAFKSQNATPKGPNAAYDFSQAA-----TTGELAANKSEMAFKAQNATTKV 155
Query: 194 QPASLNAFKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMNASKASQAV----- 248
P + F A++ S P + PF P N ++A A
Sbjct: 156 GPNATYNFSQSLNANDLANSRP---KTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADI 212
Query: 249 ---PTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHT----LA 301
P A Q +A +A R GK TRK +L +E+S G LA
Sbjct: 213 ETDPGISEPDGATAQTSADGSQAQNLESRTIIR-GKRTRKINNLNVEENSSGDQRRAPLA 271
Query: 302 FHDWQG-PRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSA 360
W+ P P N Q W++P SGW+ + + + P A
Sbjct: 272 AGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNP------SGWQNQTARQTPPARQSPPA 325
Query: 361 SWALSAWEGP 370
AW+ P
Sbjct: 326 RQTPPAWQNP 335
>gi|52632377 melanoma antigen family D, 1 isoform b [Homo sapiens]
Length = 778
Score = 212 bits (539), Expect = 1e-54
Identities = 126/324 (38%), Positives = 180/324 (55%), Gaps = 22/324 (6%)
Query: 305 WQGPRPWEN----LNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPS- 359
W GP W N N W+ Q W+ P +G W P + W P+
Sbjct: 362 WPGPVVWPNPLAWQNPPGWQTPPGWQTPPGWQGPPDWQGPPDWPLPPDWPLPPDWPLPTD 421
Query: 360 ----ASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLS 415
W + W P + L P +L SP S A+Q+ + + ++
Sbjct: 422 WPLPPDWIPADWPIPPDWQNL----RPSPNL--------RPSPNSRASQNPGAAQPRDVA 469
Query: 416 PLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLK 475
L ERAN LV++L++KD KVP++RSEM++ I+REY D +II RA LE FG QLK
Sbjct: 470 LLQERANKLVKYLMLKDYTKVPIKRSEMLRDIIREYTDVYPEIIERACFVLEKKFGIQLK 529
Query: 476 EIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFK 535
EID + H YI+I+ G ++ + D PK GLL+V+L +IFM GN E +++ L K
Sbjct: 530 EIDKEEHLYILISTPESLAG-ILGTTKDTPKLGLLLVILGVIFMNGNRASEAVLWEALRK 588
Query: 536 LGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVL 595
+GL + L G+ +KL+T FV+QKYL+YRR+P + P EYEFLWG R++ ETSKM VL
Sbjct: 589 MGLRPGVRHPLLGDLRKLLTYEFVKQKYLDYRRVPNSNPPEYEFLWGLRSYHETSKMKVL 648
Query: 596 RFLAKLHKKDPQSWPFHYLEALAE 619
RF+A++ K+DP+ W ++EA E
Sbjct: 649 RFIAEVQKRDPRDWTAQFMEAADE 672
Score = 34.7 bits (78), Expect = 0.28
Identities = 66/310 (21%), Positives = 101/310 (32%), Gaps = 35/310 (11%)
Query: 81 PSWQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRASSIDRRGSSKERRTSSKERR 140
P+ QA A PP A + + + P + + +G + S
Sbjct: 41 PTNQATAAASPQSSQPPTANEMADIQVSAAAARPKSAFKVQNATTKGPNGVYDFSQAHNA 100
Query: 141 AP---SKDRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETFAPSSSVF----PATSQF 193
++ + F + PK +AA AA T E A S + AT++
Sbjct: 101 KDVPNTQPKAAFKSQNATPKGPNAAYDFSQAA-----TTGELAANKSEMAFKAQNATTKV 155
Query: 194 QPASLNAFKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMNASKASQAV----- 248
P + F A++ S P + PF P N ++A A
Sbjct: 156 GPNATYNFSQSLNANDLANSRP---KTPFKAWNDTTKAPTADTQTQNVNQAKMATSQADI 212
Query: 249 ---PTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHT----LA 301
P A Q +A +A R GK TRK +L +E+S G LA
Sbjct: 213 ETDPGISEPDGATAQTSADGSQAQNLESRTIIR-GKRTRKINNLNVEENSSGDQRRAPLA 271
Query: 302 FHDWQG-PRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSA 360
W+ P P N Q W++P SGW+ + + + P A
Sbjct: 272 AGTWRSAPVPVTTQNPPGAPPNVLWQTPLAWQNP------SGWQNQTARQTPPARQSPPA 325
Query: 361 SWALSAWEGP 370
AW+ P
Sbjct: 326 RQTPPAWQNP 335
>gi|29826296 melanoma antigen family F, 1 [Homo sapiens]
Length = 307
Score = 197 bits (500), Expect = 3e-50
Identities = 110/241 (45%), Positives = 146/241 (60%), Gaps = 1/241 (0%)
Query: 380 ESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQ 439
E G+ +E A G+ A + + L+ LVQFLLVKD+ K P+
Sbjct: 39 EELGAGREEGAAEPALTRKGARALAAKALARRRAYRRLNRTVAELVQFLLVKDKKKSPIT 98
Query: 440 RSEMVKVILREYKDECLDIINRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVA 499
RSEMVK ++ + K DII RA L FG++LK+ D K+H YI+INKL
Sbjct: 99 RSEMVKYVIGDLKILFPDIIARAAEHLRYVFGFELKQFDRKHHTYILINKLKPLEEEEEE 158
Query: 500 SYL-DRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVF 558
D P+ GLLM++L LI+M+GN RE ++ L +LG+ + + LFG K+LI E F
Sbjct: 159 DLGGDGPRLGLLMMILGLIYMRGNSAREAQVWEMLRRLGVQPSKYHFLFGYPKRLIMEDF 218
Query: 559 VRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALA 618
V+Q+YL YRR+P+T P EYEF WGPR+ LE SKM VL F+AKLHKK+PQ WP Y EALA
Sbjct: 219 VQQRYLSYRRVPHTNPPEYEFSWGPRSNLEISKMEVLGFVAKLHKKEPQHWPVQYREALA 278
Query: 619 E 619
+
Sbjct: 279 D 279
>gi|89276766 trophinin isoform 5 [Homo sapiens]
Length = 1431
Score = 193 bits (491), Expect = 4e-49
Identities = 99/201 (49%), Positives = 138/201 (68%), Gaps = 1/201 (0%)
Query: 417 LDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKE 476
L ERAN LV++LLVKDQ K+P++RS+M++ +++EY + +II RA+ LE F LKE
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 477 IDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKL 536
ID ++ YI+I+ G ++ + D PK GLLMV+LS+IFM GN E +I+ L KL
Sbjct: 504 IDKQSSLYILISTQESSAG-ILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 537 GLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLR 596
GL + LFG +KLIT+ FV+QKYLEY+R+P + P EYEF WG R++ ETSKM VL+
Sbjct: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
Query: 597 FLAKLHKKDPQSWPFHYLEAL 617
F ++ KKDP+ W Y EA+
Sbjct: 623 FACRVQKKDPKDWAVQYREAV 643
Score = 37.7 bits (86), Expect = 0.033
Identities = 76/311 (24%), Positives = 113/311 (36%), Gaps = 31/311 (9%)
Query: 5 EVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPL------VQLEQPFQGAPPSQKAVQI 58
EV TQA + AQ + + + A+ AQ P +QL+ P Q + I
Sbjct: 123 EVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNI 182
Query: 59 QLPPQQAQASGPQAEVPTLPLQPSWQ---APPAVLQAQPGPPVAAANFPLGSAKSLM--T 113
P AS P + S A A+ A A A + + T
Sbjct: 183 HAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITNET 242
Query: 114 PSGECRASSIDRRGSSKERRTSSKERRAPSKDRMIFAATFCAPKAVSAARAHL------- 166
S A+SI + +SK R+T +K ++ T A + + A+ +
Sbjct: 243 ASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKSKG 302
Query: 167 -PAAWKNLPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYALQDPFACV 225
AA + + E + T+Q A+L +G A K+ Q P A
Sbjct: 303 KKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNADQ 362
Query: 226 EALPAVPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRS-GKATR 284
A + Q N++A + AAA QA A A + S+EP R+ GK R
Sbjct: 363 GAQAKIASA-QTNVSALETQ---------VAAAVQALADDYLA-QLSLEPTTRTRGKRNR 411
Query: 285 KKKHLEAQEDS 295
K KHL E S
Sbjct: 412 KSKHLNGDERS 422
>gi|29540551 trophinin isoform 2 [Homo sapiens]
Length = 706
Score = 193 bits (491), Expect = 4e-49
Identities = 99/201 (49%), Positives = 138/201 (68%), Gaps = 1/201 (0%)
Query: 417 LDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKE 476
L ERAN LV++LLVKDQ K+P++RS+M++ +++EY + +II RA+ LE F LKE
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 477 IDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKL 536
ID ++ YI+I+ G ++ + D PK GLLMV+LS+IFM GN E +I+ L KL
Sbjct: 504 IDKQSSLYILISTQESSAG-ILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 537 GLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLR 596
GL + LFG +KLIT+ FV+QKYLEY+R+P + P EYEF WG R++ ETSKM VL+
Sbjct: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
Query: 597 FLAKLHKKDPQSWPFHYLEAL 617
F ++ KKDP+ W Y EA+
Sbjct: 623 FACRVQKKDPKDWAVQYREAV 643
Score = 37.7 bits (86), Expect = 0.033
Identities = 76/311 (24%), Positives = 113/311 (36%), Gaps = 31/311 (9%)
Query: 5 EVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPL------VQLEQPFQGAPPSQKAVQI 58
EV TQA + AQ + + + A+ AQ P +QL+ P Q + I
Sbjct: 123 EVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNI 182
Query: 59 QLPPQQAQASGPQAEVPTLPLQPSWQ---APPAVLQAQPGPPVAAANFPLGSAKSLM--T 113
P AS P + S A A+ A A A + + T
Sbjct: 183 HAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITNET 242
Query: 114 PSGECRASSIDRRGSSKERRTSSKERRAPSKDRMIFAATFCAPKAVSAARAHL------- 166
S A+SI + +SK R+T +K ++ T A + + A+ +
Sbjct: 243 ASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKSKG 302
Query: 167 -PAAWKNLPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYALQDPFACV 225
AA + + E + T+Q A+L +G A K+ Q P A
Sbjct: 303 KKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNADQ 362
Query: 226 EALPAVPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRS-GKATR 284
A + Q N++A + AAA QA A A + S+EP R+ GK R
Sbjct: 363 GAQAKIASA-QTNVSALETQ---------VAAAVQALADDYLA-QLSLEPTTRTRGKRNR 411
Query: 285 KKKHLEAQEDS 295
K KHL E S
Sbjct: 412 KSKHLNGDERS 422
>gi|29540541 trophinin isoform 2 [Homo sapiens]
Length = 706
Score = 193 bits (491), Expect = 4e-49
Identities = 99/201 (49%), Positives = 138/201 (68%), Gaps = 1/201 (0%)
Query: 417 LDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKE 476
L ERAN LV++LLVKDQ K+P++RS+M++ +++EY + +II RA+ LE F LKE
Sbjct: 444 LQERANKLVKYLLVKDQTKIPIKRSDMLRDVIQEYDEYFPEIIERASYTLEKMFRVNLKE 503
Query: 477 IDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKL 536
ID ++ YI+I+ G ++ + D PK GLLMV+LS+IFM GN E +I+ L KL
Sbjct: 504 IDKQSSLYILISTQESSAG-ILGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKL 562
Query: 537 GLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLR 596
GL + LFG +KLIT+ FV+QKYLEY+R+P + P EYEF WG R++ ETSKM VL+
Sbjct: 563 GLRPGVRHSLFGEVRKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLK 622
Query: 597 FLAKLHKKDPQSWPFHYLEAL 617
F ++ KKDP+ W Y EA+
Sbjct: 623 FACRVQKKDPKDWAVQYREAV 643
Score = 37.7 bits (86), Expect = 0.033
Identities = 76/311 (24%), Positives = 113/311 (36%), Gaps = 31/311 (9%)
Query: 5 EVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPL------VQLEQPFQGAPPSQKAVQI 58
EV TQA + AQ + + + A+ AQ P +QL+ P Q + I
Sbjct: 123 EVTNTQASSVTAQPKKANKMKRVTAKAAQGSQSPTGHEGGTIQLKSPLQVLKLPVISQNI 182
Query: 59 QLPPQQAQASGPQAEVPTLPLQPSWQ---APPAVLQAQPGPPVAAANFPLGSAKSLM--T 113
P AS P + S A A+ A A A + + T
Sbjct: 183 HAPIANESASSQALITSIKPKKASKAKKAANKAIASATEVSLAATATHTATTQGQITNET 242
Query: 114 PSGECRASSIDRRGSSKERRTSSKERRAPSKDRMIFAATFCAPKAVSAARAHL------- 166
S A+SI + +SK R+T +K ++ T A + + A+ +
Sbjct: 243 ASIHTTAASIRTKKASKARKTIAKVINTDTEHIEALNVTDAATRQIEASVVAIRPKKSKG 302
Query: 167 -PAAWKNLPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYALQDPFACV 225
AA + + E + T+Q A+L +G A K+ Q P A
Sbjct: 303 KKAASRGPNSVSEISEAPLATQIVTNQALAATLRVKRGSRARKAATKARATESQTPNADQ 362
Query: 226 EALPAVPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRS-GKATR 284
A + Q N++A + AAA QA A A + S+EP R+ GK R
Sbjct: 363 GAQAKIASA-QTNVSALETQ---------VAAAVQALADDYLA-QLSLEPTTRTRGKRNR 411
Query: 285 KKKHLEAQEDS 295
K KHL E S
Sbjct: 412 KSKHLNGDERS 422
>gi|29337296 melanoma antigen family D, 4B isoform 2 [Homo sapiens]
Length = 739
Score = 187 bits (475), Expect = 3e-47
Identities = 159/529 (30%), Positives = 234/529 (44%), Gaps = 89/529 (16%)
Query: 173 LPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYAL----------QDPF 222
L PET A ++ A AS A + +AA+ T S A +D
Sbjct: 89 LQLDPETLANETAARAANVARAAASNRAARAAAAAARTAFSQVVASHRVATPQVSGEDTQ 148
Query: 223 ACVEALPAVPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKT----------- 271
A A P+P + + + SQ + T MA AP +A +Q S
Sbjct: 149 PTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSA 208
Query: 272 ---SVEPPRRSGKATRKKKHLEAQEDSRGHT-------LAFHDWQGPRPWENLNLSDWEV 321
S P R A R Q D T +AF + P P +
Sbjct: 209 CAFSQAPCAREVDANRPSTAFLGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATEGPSA 268
Query: 322 QSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGW-----------------------EGP 358
S + +G R + G + ++ + W EG
Sbjct: 269 ASGVPQTGPGREVAATRPKTTKSGKALAK--TRWVEPQNVVAAAAAKAKMATSIPEPEGA 326
Query: 359 SASWALSAWE------GPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQ 412
+A+ A + E G T ++ L + SS E +V P A+Q + V AQ
Sbjct: 327 AAATAQHSAEPWARMGGKRTKKSKHLDDEYESSEEE--RETPAVPPTWRASQPSLTVRAQ 384
Query: 413 -----PLSP-------------------LDERANALVQFLLVKDQAKVPVQRSEMVKVIL 448
P++P L ERAN LV++L++KD K+P++R++M+K ++
Sbjct: 385 LAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIKDYKKIPIKRADMLKDVI 444
Query: 449 REYKDECLDIINRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFG 508
REY + +II RA LE FG LKEID + H YI++ + L+ D P+
Sbjct: 445 REYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD-SSARLLGKTKDTPRLS 503
Query: 509 LLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRR 568
LL+V+L +IFM GN E +++ L K+GL + G+ +KLIT+ FV+QKYLEY++
Sbjct: 504 LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKK 563
Query: 569 IPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEAL 617
IP + P EYEFLWG RA ETSKM VLRF+A+ +DP+ W H+LEA+
Sbjct: 564 IPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAV 612
>gi|29337294 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
Length = 741
Score = 187 bits (475), Expect = 3e-47
Identities = 159/529 (30%), Positives = 234/529 (44%), Gaps = 89/529 (16%)
Query: 173 LPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYAL----------QDPF 222
L PET A ++ A AS A + +AA+ T S A +D
Sbjct: 89 LQLDPETLANETAARAANVARAAASNRAARAAAAAARTAFSQVVASHRVATPQVSGEDTQ 148
Query: 223 ACVEALPAVPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKT----------- 271
A A P+P + + + SQ + T MA AP +A +Q S
Sbjct: 149 PTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSA 208
Query: 272 ---SVEPPRRSGKATRKKKHLEAQEDSRGHT-------LAFHDWQGPRPWENLNLSDWEV 321
S P R A R Q D T +AF + P P +
Sbjct: 209 CAFSQAPCAREVDANRPSTAFLGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATEGPSA 268
Query: 322 QSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGW-----------------------EGP 358
S + +G R + G + ++ + W EG
Sbjct: 269 ASGVPQTGPGREVAATRPKTTKSGKALAK--TRWVEPQNVVAAAAAKAKMATSIPEPEGA 326
Query: 359 SASWALSAWE------GPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQ 412
+A+ A + E G T ++ L + SS E +V P A+Q + V AQ
Sbjct: 327 AAATAQHSAEPWARMGGKRTKKSKHLDDEYESSEEE--RETPAVPPTWRASQPSLTVRAQ 384
Query: 413 -----PLSP-------------------LDERANALVQFLLVKDQAKVPVQRSEMVKVIL 448
P++P L ERAN LV++L++KD K+P++R++M+K ++
Sbjct: 385 LAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIKDYKKIPIKRADMLKDVI 444
Query: 449 REYKDECLDIINRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFG 508
REY + +II RA LE FG LKEID + H YI++ + L+ D P+
Sbjct: 445 REYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD-SSARLLGKTKDTPRLS 503
Query: 509 LLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRR 568
LL+V+L +IFM GN E +++ L K+GL + G+ +KLIT+ FV+QKYLEY++
Sbjct: 504 LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKK 563
Query: 569 IPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEAL 617
IP + P EYEFLWG RA ETSKM VLRF+A+ +DP+ W H+LEA+
Sbjct: 564 IPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAV 612
>gi|29337292 melanoma antigen family D, 4B isoform 1 [Homo sapiens]
Length = 741
Score = 187 bits (475), Expect = 3e-47
Identities = 159/529 (30%), Positives = 234/529 (44%), Gaps = 89/529 (16%)
Query: 173 LPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYAL----------QDPF 222
L PET A ++ A AS A + +AA+ T S A +D
Sbjct: 89 LQLDPETLANETAARAANVARAAASNRAARAAAAAARTAFSQVVASHRVATPQVSGEDTQ 148
Query: 223 ACVEALPAVPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKT----------- 271
A A P+P + + + SQ + T MA AP +A +Q S
Sbjct: 149 PTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSA 208
Query: 272 ---SVEPPRRSGKATRKKKHLEAQEDSRGHT-------LAFHDWQGPRPWENLNLSDWEV 321
S P R A R Q D T +AF + P P +
Sbjct: 209 CAFSQAPCAREVDANRPSTAFLGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATEGPSA 268
Query: 322 QSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGW-----------------------EGP 358
S + +G R + G + ++ + W EG
Sbjct: 269 ASGVPQTGPGREVAATRPKTTKSGKALAK--TRWVEPQNVVAAAAAKAKMATSIPEPEGA 326
Query: 359 SASWALSAWE------GPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQ 412
+A+ A + E G T ++ L + SS E +V P A+Q + V AQ
Sbjct: 327 AAATAQHSAEPWARMGGKRTKKSKHLDDEYESSEEE--RETPAVPPTWRASQPSLTVRAQ 384
Query: 413 -----PLSP-------------------LDERANALVQFLLVKDQAKVPVQRSEMVKVIL 448
P++P L ERAN LV++L++KD K+P++R++M+K ++
Sbjct: 385 LAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIKDYKKIPIKRADMLKDVI 444
Query: 449 REYKDECLDIINRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFG 508
REY + +II RA LE FG LKEID + H YI++ + L+ D P+
Sbjct: 445 REYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD-SSARLLGKTKDTPRLS 503
Query: 509 LLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRR 568
LL+V+L +IFM GN E +++ L K+GL + G+ +KLIT+ FV+QKYLEY++
Sbjct: 504 LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKK 563
Query: 569 IPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEAL 617
IP + P EYEFLWG RA ETSKM VLRF+A+ +DP+ W H+LEA+
Sbjct: 564 IPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAV 612
>gi|149274614 melanoma antigen family D, 4 [Homo sapiens]
Length = 739
Score = 187 bits (475), Expect = 3e-47
Identities = 159/529 (30%), Positives = 234/529 (44%), Gaps = 89/529 (16%)
Query: 173 LPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYAL----------QDPF 222
L PET A ++ A AS A + +AA+ T S A +D
Sbjct: 89 LQLDPETLANETAARAANVARAAASNRAARAAAAAARTAFSQVVASHRVATPQVSGEDTQ 148
Query: 223 ACVEALPAVPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKT----------- 271
A A P+P + + + SQ + T MA AP +A +Q S
Sbjct: 149 PTTYAAEAQGPTPEPPLASPQTSQMLVTSKMAAPEAPATSAQSQTGSPAQEAATEGPSSA 208
Query: 272 ---SVEPPRRSGKATRKKKHLEAQEDSRGHT-------LAFHDWQGPRPWENLNLSDWEV 321
S P R A R Q D T +AF + P P +
Sbjct: 209 CAFSQAPCAREVDANRPSTAFLGQNDVFDFTQPAGVSGMAFPRPKRPAPAQEAATEGPSA 268
Query: 322 QSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGW-----------------------EGP 358
S + +G R + G + ++ + W EG
Sbjct: 269 ASGVPQTGPGREVAATRPKTTKSGKALAK--TRWVEPQNVVAAAAAKAKMATSIPEPEGA 326
Query: 359 SASWALSAWE------GPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQ 412
+A+ A + E G T ++ L + SS E +V P A+Q + V AQ
Sbjct: 327 AAATAQHSAEPWARMGGKRTKKSKHLDDEYESSEEE--RETPAVPPTWRASQPSLTVRAQ 384
Query: 413 -----PLSP-------------------LDERANALVQFLLVKDQAKVPVQRSEMVKVIL 448
P++P L ERAN LV++L++KD K+P++R++M+K ++
Sbjct: 385 LAPRPPMAPRSQIPSRHVLCLPPRNVTLLQERANKLVKYLMIKDYKKIPIKRADMLKDVI 444
Query: 449 REYKDECLDIINRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFG 508
REY + +II RA LE FG LKEID + H YI++ + L+ D P+
Sbjct: 445 REYDEHFPEIIERATYTLEKKFGIHLKEIDKEEHLYILVCTRD-SSARLLGKTKDTPRLS 503
Query: 509 LLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRR 568
LL+V+L +IFM GN E +++ L K+GL + G+ +KLIT+ FV+QKYLEY++
Sbjct: 504 LLLVILGVIFMNGNRASEAVLWEALRKMGLRPGVRHPFLGDLRKLITDDFVKQKYLEYKK 563
Query: 569 IPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEAL 617
IP + P EYEFLWG RA ETSKM VLRF+A+ +DP+ W H+LEA+
Sbjct: 564 IPNSNPPEYEFLWGLRARHETSKMRVLRFIAQNQNRDPREWKAHFLEAV 612
>gi|4505085 melanoma antigen family B, 4 [Homo sapiens]
Length = 346
Score = 187 bits (474), Expect = 3e-47
Identities = 105/278 (37%), Positives = 165/278 (59%), Gaps = 14/278 (5%)
Query: 356 EGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGS------------SAT 403
E PS+S ++ + S+S A G+ + P P + A GS S++
Sbjct: 37 ESPSSSSSVLR-DTASSSLAFGIPQEPQREPPTTSAAAAMSCTGSDKGDESQDEENASSS 95
Query: 404 QDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRAN 463
Q ++ E L + LVQFLL K + K P ++EM+K+I ++YK+ +I + +
Sbjct: 96 QASTSTERSLKDSLTRKTKMLVQFLLYKYKMKEPTTKAEMLKIISKKYKEHFPEIFRKVS 155
Query: 464 NKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNC 523
+ E FG LKE++ H+YI+++ LG + GN +++ P+ GLLM +LS+IF+ GNC
Sbjct: 156 QRTELVFGLALKEVNPTTHSYILVSMLGPNDGNQSSAWT-LPRNGLLMPLLSVIFLNGNC 214
Query: 524 VREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGP 583
RE+ I+ FL LG+ + + +FG +KLIT+ V++KYLEY+++P ++P Y+FLWGP
Sbjct: 215 AREEEIWEFLNMLGIYDGKRHLIFGEPRKLITQDLVQEKYLEYQQVPNSDPPRYQFLWGP 274
Query: 584 RAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECE 621
RA ETSKM VL FLAK++ P ++P Y EAL + E
Sbjct: 275 RAHAETSKMKVLEFLAKVNDTTPNNFPLLYEEALRDEE 312
>gi|29171711 melanoma antigen family B, 1 [Homo sapiens]
Length = 347
Score = 177 bits (448), Expect = 3e-44
Identities = 97/278 (34%), Positives = 159/278 (57%), Gaps = 14/278 (5%)
Query: 356 EGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVA------------SVSPGSSAT 403
E PS+S L + P++S A G+ + P + P + A +S +
Sbjct: 37 ECPSSSPVLG--DTPTSSPAAGIPQKPQGAPPTTTAAAAVSCTESDEGAKCQGEENASFS 94
Query: 404 QDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRAN 463
Q + E+ P+ A L+ F+L K + + P+ +++M+KV+ +YKD +I+N A+
Sbjct: 95 QATTSTESSVKDPVAWEAGMLMHFILRKYKMREPIMKADMLKVVDEKYKDHFTEILNGAS 154
Query: 464 NKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNC 523
+LE FG LKE + H Y +++KL +++ D P+ GLLM +L +IF+KGN
Sbjct: 155 RRLELVFGLDLKEDNPSGHTYTLVSKLNLTNDGNLSNDWDFPRNGLLMPLLGVIFLKGNS 214
Query: 524 VREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGP 583
E+ I+ F+ LG E + ++G +K IT+ V++KYL+Y ++P ++P Y+FLWGP
Sbjct: 215 ATEEEIWKFMNVLGAYDGEEHLIYGEPRKFITQDLVQEKYLKYEQVPNSDPPRYQFLWGP 274
Query: 584 RAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECE 621
RA+ ET+KM VL FLAK++ P+ +P HY EAL + E
Sbjct: 275 RAYAETTKMKVLEFLAKMNGATPRDFPSHYEEALRDEE 312
>gi|29171709 melanoma antigen family B, 1 [Homo sapiens]
Length = 347
Score = 177 bits (448), Expect = 3e-44
Identities = 97/278 (34%), Positives = 159/278 (57%), Gaps = 14/278 (5%)
Query: 356 EGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVA------------SVSPGSSAT 403
E PS+S L + P++S A G+ + P + P + A +S +
Sbjct: 37 ECPSSSPVLG--DTPTSSPAAGIPQKPQGAPPTTTAAAAVSCTESDEGAKCQGEENASFS 94
Query: 404 QDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRAN 463
Q + E+ P+ A L+ F+L K + + P+ +++M+KV+ +YKD +I+N A+
Sbjct: 95 QATTSTESSVKDPVAWEAGMLMHFILRKYKMREPIMKADMLKVVDEKYKDHFTEILNGAS 154
Query: 464 NKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNC 523
+LE FG LKE + H Y +++KL +++ D P+ GLLM +L +IF+KGN
Sbjct: 155 RRLELVFGLDLKEDNPSGHTYTLVSKLNLTNDGNLSNDWDFPRNGLLMPLLGVIFLKGNS 214
Query: 524 VREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGP 583
E+ I+ F+ LG E + ++G +K IT+ V++KYL+Y ++P ++P Y+FLWGP
Sbjct: 215 ATEEEIWKFMNVLGAYDGEEHLIYGEPRKFITQDLVQEKYLKYEQVPNSDPPRYQFLWGP 274
Query: 584 RAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECE 621
RA+ ET+KM VL FLAK++ P+ +P HY EAL + E
Sbjct: 275 RAYAETTKMKVLEFLAKMNGATPRDFPSHYEEALRDEE 312
>gi|29171707 melanoma antigen family B, 1 [Homo sapiens]
Length = 347
Score = 177 bits (448), Expect = 3e-44
Identities = 97/278 (34%), Positives = 159/278 (57%), Gaps = 14/278 (5%)
Query: 356 EGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVA------------SVSPGSSAT 403
E PS+S L + P++S A G+ + P + P + A +S +
Sbjct: 37 ECPSSSPVLG--DTPTSSPAAGIPQKPQGAPPTTTAAAAVSCTESDEGAKCQGEENASFS 94
Query: 404 QDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRAN 463
Q + E+ P+ A L+ F+L K + + P+ +++M+KV+ +YKD +I+N A+
Sbjct: 95 QATTSTESSVKDPVAWEAGMLMHFILRKYKMREPIMKADMLKVVDEKYKDHFTEILNGAS 154
Query: 464 NKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNC 523
+LE FG LKE + H Y +++KL +++ D P+ GLLM +L +IF+KGN
Sbjct: 155 RRLELVFGLDLKEDNPSGHTYTLVSKLNLTNDGNLSNDWDFPRNGLLMPLLGVIFLKGNS 214
Query: 524 VREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGP 583
E+ I+ F+ LG E + ++G +K IT+ V++KYL+Y ++P ++P Y+FLWGP
Sbjct: 215 ATEEEIWKFMNVLGAYDGEEHLIYGEPRKFITQDLVQEKYLKYEQVPNSDPPRYQFLWGP 274
Query: 584 RAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECE 621
RA+ ET+KM VL FLAK++ P+ +P HY EAL + E
Sbjct: 275 RAYAETTKMKVLEFLAKMNGATPRDFPSHYEEALRDEE 312
>gi|58530863 melanoma antigen family A, 10 [Homo sapiens]
Length = 369
Score = 175 bits (444), Expect = 1e-43
Identities = 101/299 (33%), Positives = 166/299 (55%), Gaps = 30/299 (10%)
Query: 323 SPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSASWALSAWEGPSTSRALGLSESP 382
+P +VS D E PN P+ A A PS +L L +S
Sbjct: 70 TPEEVSADDETPNPPQS-----------------------AQIACSSPSVVASLPLDQSD 106
Query: 383 GSSLPVVVSEVASVSPGSSATQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSE 442
S S SP + +S E+ P S +DE+ LVQFLL K Q K P+ ++E
Sbjct: 107 EGS-----SSQKEESPSTLQVLPDS--ESLPRSEIDEKVTDLVQFLLFKYQMKEPITKAE 159
Query: 443 MVKVILREYKDECLDIINRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYL 502
+++ +++ Y+D + + A+ + FG +KE+D H+++++ LG +++
Sbjct: 160 ILESVIKNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQ 219
Query: 503 DRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQK 562
PK G+L+++LS+IF++G C E++I+ L +GL + ++G +KL+T+ +V++
Sbjct: 220 SMPKTGILILILSIIFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGEPRKLLTQDWVQEN 279
Query: 563 YLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECE 621
YLEYR++P ++PA YEFLWGPRA E KM +L+FLAK++ DP+S+P Y EAL + E
Sbjct: 280 YLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEE 338
>gi|10567820 melanoma antigen family A, 10 [Homo sapiens]
Length = 369
Score = 175 bits (444), Expect = 1e-43
Identities = 101/299 (33%), Positives = 166/299 (55%), Gaps = 30/299 (10%)
Query: 323 SPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSASWALSAWEGPSTSRALGLSESP 382
+P +VS D E PN P+ A A PS +L L +S
Sbjct: 70 TPEEVSADDETPNPPQS-----------------------AQIACSSPSVVASLPLDQSD 106
Query: 383 GSSLPVVVSEVASVSPGSSATQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSE 442
S S SP + +S E+ P S +DE+ LVQFLL K Q K P+ ++E
Sbjct: 107 EGS-----SSQKEESPSTLQVLPDS--ESLPRSEIDEKVTDLVQFLLFKYQMKEPITKAE 159
Query: 443 MVKVILREYKDECLDIINRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYL 502
+++ +++ Y+D + + A+ + FG +KE+D H+++++ LG +++
Sbjct: 160 ILESVIKNYEDHFPLLFSEASECMLLVFGIDVKEVDPTGHSFVLVTSLGLTYDGMLSDVQ 219
Query: 503 DRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQK 562
PK G+L+++LS+IF++G C E++I+ L +GL + ++G +KL+T+ +V++
Sbjct: 220 SMPKTGILILILSIIFIEGYCTPEEVIWEALNMMGLYDGMEHLIYGEPRKLLTQDWVQEN 279
Query: 563 YLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECE 621
YLEYR++P ++PA YEFLWGPRA E KM +L+FLAK++ DP+S+P Y EAL + E
Sbjct: 280 YLEYRQVPGSDPARYEFLWGPRAHAEIRKMSLLKFLAKVNGSDPRSFPLWYEEALKDEE 338
>gi|29171714 melanoma antigen family B, 3 [Homo sapiens]
Length = 346
Score = 172 bits (435), Expect = 1e-42
Identities = 104/281 (37%), Positives = 158/281 (56%), Gaps = 15/281 (5%)
Query: 371 STSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVE-----AQPLS--------PL 417
S R+ + P +L S VS S NSK+E +Q LS PL
Sbjct: 54 SAGRSRSALKKPQRALSTTTS--VDVSYKKSYKGANSKIEKKQSFSQGLSSTVQSRTDPL 111
Query: 418 DERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKEI 477
+ N LVQFL+ + K P+ +++M+K++ + +K+ +I+ +A+ +E FG LK++
Sbjct: 112 IMKTNMLVQFLMEMYKMKKPIMKADMLKIVQKSHKNCFPEILKKASFNMEVVFGVDLKKV 171
Query: 478 DTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLG 537
D+ +Y++++K+ V PK GLL+ +L +IFMKGNC E+ I+ FL K+
Sbjct: 172 DSTKDSYVLVSKMDLPNNGTVTRGRGFPKTGLLLNLLGVIFMKGNCATEEKIWEFLNKMR 231
Query: 538 LDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRF 597
+ + + +FG +KLIT+ V+ KYLEYR++P + PA YEFLWGPRA ETSKM VL F
Sbjct: 232 IYDGKKHFIFGEPRKLITQDLVKLKYLEYRQVPNSNPARYEFLWGPRAHAETSKMKVLEF 291
Query: 598 LAKLHKKDPQSWPFHYLEALAECEWEDTDEDEPDTGDSAHG 638
AK++K P ++ F Y EAL + E + G SA G
Sbjct: 292 WAKVNKTVPSAFQFWYEEALRDEEERVQAAAMLNDGSSAMG 332
>gi|153791873 melanoma antigen family B, 16 [Homo sapiens]
Length = 324
Score = 172 bits (435), Expect = 1e-42
Identities = 90/221 (40%), Positives = 137/221 (61%)
Query: 401 SATQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIIN 460
S+++D S P LD++ LV F+L K Q K P+ +++M+K+I+++ + +I+
Sbjct: 97 SSSEDTSDPRNVPADALDQKVAFLVNFMLHKCQMKKPITKADMLKIIIKDDESHFSEILL 156
Query: 461 RANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMK 520
RA+ LE FG + E+D H Y + KLG +++ PK GLL++VL +IFMK
Sbjct: 157 RASEHLEMIFGLDVVEVDPTTHCYGLFIKLGLTYDGMLSGEKGVPKTGLLIIVLGVIFMK 216
Query: 521 GNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFL 580
GN E+ ++ L G+ + + +FG + LIT+ FV++KYLEY+++ ++PA YEFL
Sbjct: 217 GNRATEEEVWEVLNLTGVYSGKKHFIFGEPRMLITKDFVKEKYLEYQQVANSDPARYEFL 276
Query: 581 WGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECE 621
WGPRA ETSKM VL F+AK+H P S+P Y EAL E E
Sbjct: 277 WGPRAKAETSKMKVLEFVAKVHGSYPHSFPSQYAEALKEEE 317
>gi|222418639 melanoma antigen family B, 2 [Homo sapiens]
Length = 319
Score = 169 bits (427), Expect = 1e-41
Identities = 98/281 (34%), Positives = 155/281 (55%), Gaps = 5/281 (1%)
Query: 344 EGPSTSRILSGW---EGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGS 400
E P S +SG P+A P+T+ A S S S + S
Sbjct: 37 EAPCCSSSVSGGAASSSPAAGIPQEPQRAPTTAAAAAAGVSSTKSKKGAKSHQGEKNASS 96
Query: 401 SATQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIIN 460
S ++K ++ PL ++ +LVQFLL K + K V + EM+K++ + +++ +I+
Sbjct: 97 SQASTSTKSPSE--DPLTRKSGSLVQFLLYKYKIKKSVTKGEMLKIVGKRFREHFPEILK 154
Query: 461 RANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMK 520
+A+ L FG +L +++ H Y I+K+ + S D P+ LLM +L +IF+
Sbjct: 155 KASEGLSVVFGLELNKVNPNGHTYTFIDKVDLTDEESLLSSWDFPRRKLLMPLLGVIFLN 214
Query: 521 GNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFL 580
GN E+ I+ FL LG+ E + +FG KLIT+ V++KYLEY+++P ++P ++FL
Sbjct: 215 GNSATEEEIWEFLNMLGVYDGEEHSVFGEPWKLITKDLVQEKYLEYKQVPSSDPPRFQFL 274
Query: 581 WGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECE 621
WGPRA+ ETSKM VL FLAK++ P ++P HY EAL + E
Sbjct: 275 WGPRAYAETSKMKVLEFLAKVNGTTPCAFPTHYEEALKDEE 315
>gi|73623441 melanoma antigen family B, 10 [Homo sapiens]
Length = 347
Score = 167 bits (424), Expect = 2e-41
Identities = 86/219 (39%), Positives = 132/219 (60%)
Query: 403 TQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRA 462
TQD ++ P P+DE+ LV +LL K Q K P+ +++M++ + + K + I++RA
Sbjct: 97 TQDLEATDSFPRGPVDEKVIILVHYLLYKYQMKEPITKADMLRNVTQMSKSQFPVILSRA 156
Query: 463 NNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGN 522
+ LE FG LKE++ H Y+++NKL ++ PK GLLM VL +IF GN
Sbjct: 157 SEHLELIFGLDLKEVEPNKHIYVLVNKLDLGCDAKLSDETGVPKTGLLMTVLGIIFTNGN 216
Query: 523 CVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWG 582
CV E+ ++ +GL + +FG +KL+T+ V++ YLEY+++P ++P Y+FLWG
Sbjct: 217 CVAEEEVWKVFNTMGLYDGIEHFMFGEPRKLLTKDLVKENYLEYQQVPNSDPPRYQFLWG 276
Query: 583 PRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECE 621
PRA ETSKM VL FLAK++ P + Y EAL + E
Sbjct: 277 PRAHAETSKMKVLEFLAKVNDTAPSEFSNWYTEALQDEE 315
>gi|27734781 melanoma antigen family B, 18 [Homo sapiens]
Length = 343
Score = 166 bits (420), Expect = 6e-41
Identities = 99/280 (35%), Positives = 154/280 (55%), Gaps = 6/280 (2%)
Query: 344 EGPSTSRILSGWEGPSASWALSAWEGPSTSRAL-GLSESPGSSLPVVVSEVASVSPGSSA 402
E PS++ +L G + L A E PS AL G + + PV S S
Sbjct: 36 ESPSSAYLLFGDRPQN----LPAAETPSIPEALQGAPSTTNAIAPVSCSSNEGASSQDEK 91
Query: 403 TQDNSK-VEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINR 461
+ +S+ E PL+++ +LV FLL K + K P+ + +M+K ++R+ K +I+ R
Sbjct: 92 SLGSSREAEGWKEDPLNKKVVSLVHFLLQKYETKEPITKGDMIKFVIRKDKCHFNEILKR 151
Query: 462 ANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKG 521
A+ +E A G LKE+D H Y +KL + PK GLLM+ L +IF+ G
Sbjct: 152 ASEHMELALGVDLKEVDPIRHYYAFFSKLDLTYDETTSDEEKIPKTGLLMIALGVIFLNG 211
Query: 522 NCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLW 581
N E+ ++ + +G+ + L+G+ +K++T+ V+ KYLEY+++P ++P YEFLW
Sbjct: 212 NRAPEEAVWEIMNMMGVYADRKHFLYGDPRKVMTKDLVQLKYLEYQQVPNSDPPRYEFLW 271
Query: 582 GPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECE 621
GPRA ETSKM VL F+AK+H P ++P Y EAL + E
Sbjct: 272 GPRAHAETSKMKVLEFVAKIHDTVPSAFPSCYEEALRDEE 311
>gi|61744473 melanoma antigen family A, 11 isoform b [Homo sapiens]
Length = 400
Score = 160 bits (404), Expect = 4e-39
Identities = 82/221 (37%), Positives = 135/221 (61%)
Query: 399 GSSATQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDI 458
G S + D E+ L ++ LV LL K + K + ++EM+ +++ Y+D +I
Sbjct: 175 GPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEI 234
Query: 459 INRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIF 518
A+ ++ FG +KE+D +H+Y+++ L + + PK GLL++VL +IF
Sbjct: 235 FREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIF 294
Query: 519 MKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYE 578
M+GNC+ E++++ L +G+ + LFG K+L+T+ +V++KYL YR++P T+PA YE
Sbjct: 295 MEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDPACYE 354
Query: 579 FLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAE 619
FLWGPRA ETSKM VL ++A + +DP S+P Y +AL E
Sbjct: 355 FLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALRE 395
>gi|65507078 melanoma antigen family A, 11 isoform a [Homo sapiens]
Length = 429
Score = 160 bits (404), Expect = 4e-39
Identities = 82/221 (37%), Positives = 135/221 (61%)
Query: 399 GSSATQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDI 458
G S + D E+ L ++ LV LL K + K + ++EM+ +++ Y+D +I
Sbjct: 204 GPSTSPDLIDPESFSQDILHDKIIDLVHLLLRKYRVKGLITKAEMLGSVIKNYEDYFPEI 263
Query: 459 INRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIF 518
A+ ++ FG +KE+D +H+Y+++ L + + PK GLL++VL +IF
Sbjct: 264 FREASVCMQLLFGIDVKEVDPTSHSYVLVTSLNLSYDGIQCNEQSMPKSGLLIIVLGVIF 323
Query: 519 MKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYE 578
M+GNC+ E++++ L +G+ + LFG K+L+T+ +V++KYL YR++P T+PA YE
Sbjct: 324 MEGNCIPEEVMWEVLSIMGVYAGREHFLFGEPKRLLTQNWVQEKYLVYRQVPGTDPACYE 383
Query: 579 FLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAE 619
FLWGPRA ETSKM VL ++A + +DP S+P Y +AL E
Sbjct: 384 FLWGPRAHAETSKMKVLEYIANANGRDPTSYPSLYEDALRE 424
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,828,109
Number of Sequences: 37866
Number of extensions: 1494653
Number of successful extensions: 8256
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 434
Number of HSP's that attempted gapping in prelim test: 6381
Number of HSP's gapped (non-prelim): 1769
length of query: 646
length of database: 18,247,518
effective HSP length: 109
effective length of query: 537
effective length of database: 14,120,124
effective search space: 7582506588
effective search space used: 7582506588
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.