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Search of human proteins with 148664232
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148664232 transglutaminase 6 [Homo sapiens]
(706 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148664232 transglutaminase 6 [Homo sapiens] 1430 0.0
gi|189458821 transglutaminase 3 precursor [Homo sapiens] 664 0.0
gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens] 623 e-178
gi|16445035 transglutaminase 7 [Homo sapiens] 587 e-167
gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens] 522 e-148
gi|39777597 transglutaminase 2 isoform a [Homo sapiens] 499 e-141
gi|4507475 transglutaminase 1 [Homo sapiens] 444 e-124
gi|39777599 transglutaminase 2 isoform b [Homo sapiens] 439 e-123
gi|156627577 transglutaminase 4 (prostate) [Homo sapiens] 419 e-117
gi|119395709 coagulation factor XIII A1 subunit precursor [Homo ... 398 e-110
gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Ho... 324 2e-88
gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Ho... 323 3e-88
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] 35 0.18
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 35 0.18
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 35 0.18
gi|55741661 hypothetical protein LOC57653 [Homo sapiens] 32 1.5
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 31 3.4
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 31 3.4
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 31 3.4
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 31 4.5
gi|157419150 protein tyrosine phosphatase, receptor type, M isof... 31 4.5
gi|157419152 protein tyrosine phosphatase, receptor type, M isof... 31 4.5
>gi|148664232 transglutaminase 6 [Homo sapiens]
Length = 706
Score = 1430 bits (3701), Expect = 0.0
Identities = 706/706 (100%), Positives = 706/706 (100%)
Query: 1 MAGIRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCEEILIFTMET 60
MAGIRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCEEILIFTMET
Sbjct: 1 MAGIRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCEEILIFTMET 60
Query: 61 GPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSS 120
GPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSS
Sbjct: 61 GPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSS 120
Query: 121 HRKHSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYG 180
HRKHSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYG
Sbjct: 121 HRKHSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYG 180
Query: 181 QFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQG 240
QFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQG
Sbjct: 181 QFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQG 240
Query: 241 KYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNS 300
KYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNS
Sbjct: 241 KYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNS 300
Query: 301 AHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQ 360
AHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQ
Sbjct: 301 AHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQ 360
Query: 361 EESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKKI 420
EESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKKI
Sbjct: 361 EESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKKI 420
Query: 421 GRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIRRAGGRC 480
GRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIRRAGGRC
Sbjct: 421 GRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIRRAGGRC 480
Query: 481 LWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGATILYTR 540
LWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGATILYTR
Sbjct: 481 LWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGATILYTR 540
Query: 541 KPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKGEKLLVEK 600
KPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKGEKLLVEK
Sbjct: 541 KPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKGEKLLVEK 600
Query: 601 DITLEDFITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSIDVPTL 660
DITLEDFITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSIDVPTL
Sbjct: 601 DITLEDFITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSIDVPTL 660
Query: 661 EPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHVATAK 706
EPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHVATAK
Sbjct: 661 EPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHVATAK 706
>gi|189458821 transglutaminase 3 precursor [Homo sapiens]
Length = 693
Score = 664 bits (1714), Expect = 0.0
Identities = 354/710 (49%), Positives = 461/710 (64%), Gaps = 25/710 (3%)
Query: 1 MAGIRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCEEILIFTMET 60
MA + V ++WQ + N AHHT ++ EL++RRGQ+F + + +++ L E L F + T
Sbjct: 1 MAALGVQSINWQTAFNRQAHHTDKFSSQELILRRGQNFQVLMIMNKGLGSNERLEFIVST 60
Query: 61 GPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSS 120
GP SE+ TKAVF S G GW+A +A TLT+S++SP SA IGRY +++++ S
Sbjct: 61 GPYPSESAMTKAVFPLSNGSSG-GWSAVLQASNGNTLTISISSPASAPIGRYTMALQIFS 119
Query: 121 HRKHSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYG 180
S+ +LG F+LLFNPW D VF+ + ER+EYV D+GIIF G I GWN+G
Sbjct: 120 QGGISSVKLGTFILLFNPWLNVDSVFMGNHAEREEYVQEDAGIIFVGSTNRIGMIGWNFG 179
Query: 181 QFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQG 240
QFEEDIL+ICLSILDRS + + ATDV+ R++P YV RV+SAM+NSN+D GV+ G W G
Sbjct: 180 QFEEDILSICLSILDRSLNFRRDAATDVASRNDPKYVGRVLSAMINSNDDNGVLAGNWSG 239
Query: 241 KYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNS 300
Y GG P W GSV IL+ W K + PV+YGQCWVFAG L T LR LGI +RV++NFNS
Sbjct: 240 TYTGGRDPRSWNGSVEILKNWKKSGFSPVRYGQCWVFAGTLNTALRSLGIPSRVITNFNS 299
Query: 301 AHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQ 360
AHDTD+NLSVD Y D G L D DS+WNFHVWNE WF R DLGPSY GWQVLDATPQ
Sbjct: 300 AHDTDRNLSVDVYYDPMGNPL-DKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQ 358
Query: 361 EESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYS-NTKK 419
E S+GVF+CGPASV +REGDV L D PF+FAEVNAD ITWL+ ++ S N+
Sbjct: 359 ERSQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHT 418
Query: 420 IGRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRL-----FGVEASGRRIWIR 474
IGR ISTKAVGS++R+D+TD YKYPEGS +ERQV+ KA+ +L F +S
Sbjct: 419 IGRYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSM------ 472
Query: 475 RAGGRCLWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGA 534
L +PSI GK KV +G ++ L L L NL+ + V VN++
Sbjct: 473 ----------GLETEEQEPSIIGKLKVAGMLAVGKEVNLVLLLKNLSRDTKTVTVNMTAW 522
Query: 535 TILYTRKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKGE 594
TI+Y V E+ +S + L P+EE PI ISY++Y++ L D I + A+C V
Sbjct: 523 TIIYNGTLVHEVWKDSATMSLDPEEEAEHPIKISYAQYEKYLKSDNMIRITAVCKVPDES 582
Query: 595 KLLVEKDITLED-FITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQL 653
+++VE+DI L++ +T++VL A V V V++ NPL E V+DC LMVEGSGLL L
Sbjct: 583 EVVVERDIILDNPTLTLEVLNEARVRKPVNVQMLFSNPLDEPVRDCVLMVEGSGLLLGNL 642
Query: 654 SIDVPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHVA 703
IDVPTL P+E + V+FDI PS+SG +QL D FP IK + + VA
Sbjct: 643 KIDVPTLGPKEGSRVRFDILPSRSGTKQLLADFSCNKFPAIKAMLSIDVA 692
>gi|94981556 transglutaminase 5 isoform 1 [Homo sapiens]
Length = 720
Score = 623 bits (1607), Expect = e-178
Identities = 331/714 (46%), Positives = 467/714 (65%), Gaps = 15/714 (2%)
Query: 3 GIRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLEL-SRALDCE-EILIFTMET 60
G+ V D Q SRN HHT+E L+VRRGQ+F+LTL +R+ + +IF +ET
Sbjct: 4 GLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFVVET 63
Query: 61 GPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSS 120
GP AL T+AVF + W A E + VSL +PP+A +GRYLL I + S
Sbjct: 64 GPLPDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIHIDS 123
Query: 121 HRKHSNR-RLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNY 179
+ +LGEF+LLFNPWC ED V+L SE +RQEYV++D G I++G + IR WNY
Sbjct: 124 FQGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNY 183
Query: 180 GQFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQ 239
GQFE+ I++ICL +LD+S Q +PATD + R +P+YV+RV+ AM+NSN+D GV+ G W
Sbjct: 184 GQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWS 243
Query: 240 GKYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFN 299
Y G +P W GSVAIL++W +PV+YGQCWVFA V+CTV+RCLGI TRV++NF+
Sbjct: 244 ENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFD 303
Query: 300 SAHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATP 359
S HDTD NL +D+Y D+ GR L + +D++WNFHVWNE W AR+DL P+Y GWQVLDATP
Sbjct: 304 SGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATP 363
Query: 360 QEESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKK 419
QE S GV+ CGPASV AI+EG+V L +D PFVF+ VNAD ++WL + ++++ +T
Sbjct: 364 QEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWL-VQGGKEQKLHQDTSS 422
Query: 420 IGRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRL--FGVEASGRRIWIRRAG 477
+G ISTK++ SD R DIT+ YKY EGS +ERQV+ KA+ +L S R ++ +
Sbjct: 423 VGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSR 482
Query: 478 GRCLWRD---DLLEPATKPS----IAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVN 530
L +D L P+ +PS ++ KFK+L+PP +G D+ L N++S+ + ++VN
Sbjct: 483 PTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVN 542
Query: 531 LSGATILYTRKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMC-L 589
LS ++L+ P++ ++ + L P+E K P ISYS+Y + L+ DK I ++A+
Sbjct: 543 LSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEE 602
Query: 590 VTKGEKLLVEKDITLE-DFITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGL 648
+ EK+LV K ITL ITI VLG A+V ++++V NPL E+V+DC L VEGSGL
Sbjct: 603 KSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGL 662
Query: 649 LQEQLSIDVPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHV 702
++Q + + L+PQ +AS+ + P KSG RQ+Q ++ S F DIKG+ V+V
Sbjct: 663 FKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYV 716
>gi|16445035 transglutaminase 7 [Homo sapiens]
Length = 710
Score = 587 bits (1513), Expect = e-167
Identities = 332/722 (45%), Positives = 442/722 (61%), Gaps = 35/722 (4%)
Query: 1 MAGIRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCE-EILIFTME 59
+A +R+ VD Q SRN HHTQE L VRRGQ F L L SR + + + F E
Sbjct: 4 VATLRLESVDLQSSRNNKEHHTQEMGVKRLTVRRGQPFYLRLSFSRPFQSQNDHITFVAE 63
Query: 60 TGPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLS 119
TGP+ SE L T+A F + ++ G W+A+ +L VSL +P +AVIG Y L I +S
Sbjct: 64 TGPKPSELLGTRATFFLTRVQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYTLKIEIS 123
Query: 120 SHRKHS-NRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWN 178
+ HS LG F+LLFNPW EDDV+L SE QEY++ D G +++G E+ I + WN
Sbjct: 124 QGQGHSVTYPLGTFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERFITSWPWN 183
Query: 179 YGQFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQW 238
YGQFEEDI++IC IL++S H NPA D S R++ +YV RV+SAM+NSN+D GV+QG W
Sbjct: 184 YGQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDNGVLQGNW 243
Query: 239 QGKYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNF 298
Y G SPL W+GSVAILQ+W +PVKYGQCWVFA V+CTV+RCLG+ TRVVSNF
Sbjct: 244 GEDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVPTRVVSNF 303
Query: 299 NSAHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDAT 358
SAH+ D+NL++D Y D L D +WNFHVWNE W R+DL P YNGWQVLD T
Sbjct: 304 RSAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPGYNGWQVLDPT 363
Query: 359 PQEESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTK 418
PQ+ S G+F CGPASV AIREGDVHLA+D PFV+AEVNAD + WL + +++E + NT
Sbjct: 364 PQQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGDGQAQEILAHNTS 423
Query: 419 KIGRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVE-ASGRRIWIRRAG 477
IG+ ISTK VGSD R IT YKYPEGS +ER V+ KA ++ G + AS + + +G
Sbjct: 424 SIGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLGPQRASLPFLDLLESG 483
Query: 478 GRCLWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRV--RVNLSGAT 535
G RD +PA + + P G DL+L L R QRV + G
Sbjct: 484 G---LRD---QPAQL-----QLHLARIPEWGQDLQLLL-------RIQRVPDSTHPRGPI 525
Query: 536 ILYTRKPVAEILHES--------HAVRLGPQ--EEKRIPITISYSKYKEDLTEDKKILLA 585
L R +LH H VR+ +E + P+ + YS Y+ LT++K I ++
Sbjct: 526 GLVVRFCAQALLHGGGTQKPFWRHTVRMNLDFGKETQWPLLLPYSNYRNKLTDEKLIRVS 585
Query: 586 AMCLVTK-GEKLLVEKDITLE-DFITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMV 643
+ V + G +LV KDI LE ++I+V A VG A+ V VT+ N L+ + C +++
Sbjct: 586 GIAEVEETGRSMLVLKDICLEPPHLSIEVSERAEVGKALRVHVTLTNTLMVALSSCTMVL 645
Query: 644 EGSGLLQEQLSIDVPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHVA 703
EGSGL+ Q++ D+ TL +Q D+ P+K+GPRQLQV + S +IKG+ + V
Sbjct: 646 EGSGLINGQIAKDLGTLVAGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDIFVT 705
Query: 704 TA 705
A
Sbjct: 706 VA 707
>gi|4759230 transglutaminase 5 isoform 2 [Homo sapiens]
Length = 638
Score = 522 bits (1344), Expect = e-148
Identities = 270/572 (47%), Positives = 386/572 (67%), Gaps = 12/572 (2%)
Query: 142 EDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYGQFEEDILNICLSILDRSPGHQ 201
ED V+L SE +RQEYV++D G I++G + IR WNYGQFE+ I++ICL +LD+S Q
Sbjct: 64 EDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQ 123
Query: 202 NNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQGKYGGGTSPLHWRGSVAILQKW 261
+PATD + R +P+YV+RV+ AM+NSN+D GV+ G W Y G +P W GSVAIL++W
Sbjct: 124 TDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQW 183
Query: 262 LKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNSAHDTDQNLSVDKYVDSFGRTL 321
+PV+YGQCWVFA V+CTV+RCLGI TRV++NF+S HDTD NL +D+Y D+ GR L
Sbjct: 184 NATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRIL 243
Query: 322 EDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQEESEGVFRCGPASVTAIREGD 381
+ +D++WNFHVWNE W AR+DL P+Y GWQVLDATPQE S GV+ CGPASV AI+EG+
Sbjct: 244 GNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGE 303
Query: 382 VHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKKIGRCISTKAVGSDSRVDITDLY 441
V L +D PFVF+ VNAD ++WL + ++++ +T +G ISTK++ SD R DIT+ Y
Sbjct: 304 VDLNYDTPFVFSMVNADCMSWL-VQGGKEQKLHQDTSSVGNFISTKSIQSDERDDITENY 362
Query: 442 KYPEGSRKERQVYSKAVNRL--FGVEASGRRIWIRRAGGRCLWRD---DLLEPATKPS-- 494
KY EGS +ERQV+ KA+ +L S R ++ + L +D L P+ +PS
Sbjct: 363 KYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDV 422
Query: 495 --IAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGATILYTRKPVAEILHESHA 552
++ KFK+L+PP +G D+ L N++S+ + ++VNLS ++L+ P++ ++
Sbjct: 423 VQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAF 482
Query: 553 VRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMC-LVTKGEKLLVEKDITLE-DFITI 610
+ L P+E K P ISYS+Y + L+ DK I ++A+ + EK+LV K ITL ITI
Sbjct: 483 ITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITI 542
Query: 611 KVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSIDVPTLEPQERASVQF 670
VLG A+V ++++V NPL E+V+DC L VEGSGL ++Q + + L+PQ +AS+
Sbjct: 543 NVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIIL 602
Query: 671 DITPSKSGPRQLQVDLVSPHFPDIKGFVIVHV 702
+ P KSG RQ+Q ++ S F DIKG+ V+V
Sbjct: 603 ETVPFKSGQRQIQANMRSNKFKDIKGYRNVYV 634
Score = 45.8 bits (107), Expect = 1e-04
Identities = 21/40 (52%), Positives = 26/40 (65%)
Query: 3 GIRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTL 42
G+ V D Q SRN HHT+E L+VRRGQ+F+LTL
Sbjct: 4 GLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTL 43
>gi|39777597 transglutaminase 2 isoform a [Homo sapiens]
Length = 687
Score = 499 bits (1286), Expect = e-141
Identities = 289/706 (40%), Positives = 402/706 (56%), Gaps = 35/706 (4%)
Query: 8 KVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELS-RALDCE-EILIFTMETGPRAS 65
+ D + NG HHT + +LVVRRGQ F LTL R + + L F++ TGP S
Sbjct: 9 RCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPS 68
Query: 66 EALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSSHRKHS 125
+ TKA F + WTA Q + TL++ L +P +A IG Y LS+ S+ + S
Sbjct: 69 QEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGS 128
Query: 126 NRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYGQFEED 185
+ LG F+LLFN WC D V+L SEEERQEYVL+ G I++G K I+ WN+GQFE+
Sbjct: 129 SFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDG 188
Query: 186 ILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQGKYGGG 245
IL+ICL +LD +P N D S R +P+YV RV+S MVN N+D+GV+ G+W YG G
Sbjct: 189 ILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDG 248
Query: 246 TSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNSAHDTD 305
SP+ W GSV IL++W + VKYGQCWVFA V CTVLRCLGI TRVV+N+NSAHD +
Sbjct: 249 VSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQN 308
Query: 306 QNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQEESEG 365
NL ++ + + FG D +E +WNFH W ESW R DL P Y GWQ LD TPQE+SEG
Sbjct: 309 SNLLIEYFRNEFGEIQGDKSE-MIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEG 367
Query: 366 VFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKKIGRCIS 425
+ CGP V AI+EGD+ +D PFVFAEVNAD + W+ +D S + + + +G IS
Sbjct: 368 TYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKIS 427
Query: 426 TKAVGSDSRVDITDLYKYPEGSRKERQVYSKA--VNRLFGVEASGRRIWIRRAGGRCLWR 483
TK+VG D R DIT YKYPEGS +ER+ +++A +N+L E +G
Sbjct: 428 TKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETG--------------- 472
Query: 484 DDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGATILYTRKPV 543
+A + +V + +G D + + N T+ R+ L T+ Y
Sbjct: 473 -----------MAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILG 521
Query: 544 AEILHESHA-VRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTK-GEKLLVEKD 601
E + + L P EK +P+ I Y KY++ LTE I + A+ + LL E+D
Sbjct: 522 PECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERD 581
Query: 602 ITLED-FITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSIDVP-T 659
+ LE+ I I++LG + EV++ NPL ++ C VEG+GL +EQ ++++P
Sbjct: 582 LYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDP 641
Query: 660 LEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHVATA 705
+E E V+ D+ P G +L V+ S +KGF V + A
Sbjct: 642 VEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVIIGPA 687
>gi|4507475 transglutaminase 1 [Homo sapiens]
Length = 817
Score = 444 bits (1141), Expect = e-124
Identities = 265/709 (37%), Positives = 381/709 (53%), Gaps = 40/709 (5%)
Query: 6 VTKVDWQRSR---NGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCEEILIFTMETGP 62
V VD SR N HHT EY EL+VRRGQ F + L LSR + + + + G
Sbjct: 112 VNGVDLLSSRSDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYESSDRITLELLIGN 171
Query: 63 RASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSSHR 122
T + + G GW A + L + + + P+A+IG++ ++R S
Sbjct: 172 NPEVGKGTHVIIPVGKGGSG-GWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDA 230
Query: 123 KHSNRRL---GEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNY 179
E +LFNPWC ED V++ E+ RQEYVL++SG I+ G E I + WNY
Sbjct: 231 GEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNY 290
Query: 180 GQFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQ 239
GQF+ +L+ CL ILDR R +P+ V+RVISAMVNS +D GV+ G W
Sbjct: 291 GQFDHGVLDACLYILDRR-------GMPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWS 343
Query: 240 GKYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFN 299
G Y GT+P W GSV IL +L+ Y V YGQCWVFAGV TVLRCLG+ATR V+NFN
Sbjct: 344 GDYSRGTNPSAWVGSVEILLSYLRTGYS-VPYGQCWVFAGVTTTVLRCLGLATRTVTNFN 402
Query: 300 SAHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATP 359
SAHDTD +L++D Y D + LE L DS+WNFHVWN+ W R DL ++GWQV+DATP
Sbjct: 403 SAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATP 462
Query: 360 QEESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKK 419
QE S G+F CGP SV +I+ G V++ +D PF+FAEVN+D + W +D S + VY K
Sbjct: 463 QETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKA 522
Query: 420 IGRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIRRAGGR 479
IG I TKA+ S+ R DIT LYK+PEGS ER+ A S ++ R
Sbjct: 523 IGTLIVTKAISSNMREDITYLYKHPEGSDAERKAVETA-----AAHGSKPNVYANRGSA- 576
Query: 480 CLWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGATILYT 539
D ++ + ++ +G DL +++ L N +S + V+++L + YT
Sbjct: 577 ---EDVAMQVEAQDAV-----------MGQDLMVSVMLINHSSSRRTVKLHLYLSVTFYT 622
Query: 540 RKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKGEKLLVE 599
V L P R+ + ++Y +Y+ L + +LL V + ++L +
Sbjct: 623 GVSGTIFKETKKEVELAPGASDRVTMPVAYKEYRPHLVDQGAMLLNVSGHVKESGQVLAK 682
Query: 600 KD---ITLEDFITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSID 656
+ + D +++ +LG A+VG V++ NPL + + +EGSGL + ++ ++
Sbjct: 683 QHTFRLRTPD-LSLTLLGAAVVGQECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKI-LN 740
Query: 657 VPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHVATA 705
V + E +++ P + GPRQL L SP + G + V VA A
Sbjct: 741 VGDIGGNETVTLRQSFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPA 789
>gi|39777599 transglutaminase 2 isoform b [Homo sapiens]
Length = 548
Score = 439 bits (1130), Expect = e-123
Identities = 228/471 (48%), Positives = 300/471 (63%), Gaps = 5/471 (1%)
Query: 8 KVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELS-RALDCE-EILIFTMETGPRAS 65
+ D + NG HHT + +LVVRRGQ F LTL R + + L F++ TGP S
Sbjct: 9 RCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPS 68
Query: 66 EALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSSHRKHS 125
+ TKA F + WTA Q + TL++ L +P +A IG Y LS+ S+ + S
Sbjct: 69 QEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGS 128
Query: 126 NRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYGQFEED 185
+ LG F+LLFN WC D V+L SEEERQEYVL+ G I++G K I+ WN+GQFE+
Sbjct: 129 SFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDG 188
Query: 186 ILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQGKYGGG 245
IL+ICL +LD +P N D S R +P+YV RV+S MVN N+D+GV+ G+W YG G
Sbjct: 189 ILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDG 248
Query: 246 TSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNSAHDTD 305
SP+ W GSV IL++W + VKYGQCWVFA V CTVLRCLGI TRVV+N+NSAHD +
Sbjct: 249 VSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQN 308
Query: 306 QNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQEESEG 365
NL ++ + + FG D +E +WNFH W ESW R DL P Y GWQ LD TPQE+SEG
Sbjct: 309 SNLLIEYFRNEFGEIQGDKSE-MIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEG 367
Query: 366 VFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKKIGRCIS 425
+ CGP V AI+EGD+ +D PFVFAEVNAD + W+ +D S + + + +G IS
Sbjct: 368 TYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKIS 427
Query: 426 TKAVGSDSRVDITDLYKYPEGSRKERQVYSKA--VNRLFGVEASGRRIWIR 474
TK+VG D R DIT YKYPEGS +ER+ +++A +N+L E +G + IR
Sbjct: 428 TKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIR 478
>gi|156627577 transglutaminase 4 (prostate) [Homo sapiens]
Length = 684
Score = 419 bits (1076), Expect = e-117
Identities = 251/705 (35%), Positives = 376/705 (53%), Gaps = 40/705 (5%)
Query: 4 IRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCEEILIFTMETGPR 63
++V +D+ N +HHT E+ V RRGQ F L L L++ L L TGP
Sbjct: 8 LQVLHIDFLNQDNAVSHHTWEFQTSSPVFRRGQVFHLRLVLNQPLQSYHQLKLEFSTGPN 67
Query: 64 ASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSSHRK 123
S A HT V W A + + K +TV++ S P+A++G+Y L+++ +H
Sbjct: 68 PSIAKHTLVVLDPRTPSDHYNWQATLQNESGKEVTVAVTSSPNAILGKYQLNVKTGNHIL 127
Query: 124 HSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYGQFE 183
S + LLFNPWC ED VF+ E+ER+EY+L+D+G + G + I+ + WN+GQFE
Sbjct: 128 KSEENI--LYLLFNPWCKEDMVFMPDEDERKEYILNDTGCHYVGAARSIKCKPWNFGQFE 185
Query: 184 EDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQGKYG 243
+++L+ C+S+L S + TD R +P+ V R + AM++ +GV+ G W G Y
Sbjct: 186 KNVLDCCISLLTES----SLKPTD---RRDPVLVCRAMCAMMSFEKGQGVLIGNWTGDYE 238
Query: 244 GGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNSAHD 303
GGT+P W GS ILQ++ + + V +GQCWVFAG+L TVLR LGI R V+ F+SAHD
Sbjct: 239 GGTAPYKWTGSAPILQQYYNTK-QAVCFGQCWVFAGILTTVLRALGIPARSVTGFDSAHD 297
Query: 304 TDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQEES 363
T++NL+VD YV+ G + +T DS+WNFHVW ++W R DL Y+GWQ +DATPQE S
Sbjct: 298 TERNLTVDTYVNENGEKITSMTHDSVWNFHVWTDAWMKRPDLPKGYDGWQAVDATPQERS 357
Query: 364 EGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVY---SNTKKI 420
+GVF CGP+ +TAIR+GD+ + +D FVF+EVN D + WL +E ++ T I
Sbjct: 358 QGVFCCGPSPLTAIRKGDIFIVYDTRFVFSEVNGDRLIWLVKMVNGQEELHVISMETTSI 417
Query: 421 GRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIRRAGGRC 480
G+ ISTKAVG D R DIT YKYPEGS +ERQV A L E RR
Sbjct: 418 GKNISTKAVGQDRRRDITYEYKYPEGSSEERQVMDHAF-LLLSSEREHRRPVKENFLHMS 476
Query: 481 LWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGATILYTR 540
+ DD+L LG+ + + L T+ Q V + S LYT
Sbjct: 477 VQSDDVL-------------------LGNSVNFTVILKRKTAALQNVNILGSFELQLYTG 517
Query: 541 KPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLT--EDKKILLA-AMCLVTKGEKLL 597
K +A++ + ++ Q + + +T+ Y L +D+ ++ + + + ++++
Sbjct: 518 KKMAKLCDLNKTSQIQGQVSE-VTLTLDSKTYINSLAILDDEPVIRGFIIAEIVESKEIM 576
Query: 598 VEKDITLEDF--ITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSI 655
+ T + +I++ +G + N L + D +E G+ Q S
Sbjct: 577 ASEVFTSFQYPEFSIELPNTGRIGQLLVCNCIFKNTLAIPLTDVKFSLESLGISSLQTS- 635
Query: 656 DVPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIV 700
D T++P E Q TP K+GP++ V L S +I IV
Sbjct: 636 DHGTVQPGETIQSQIKCTPIKTGPKKFIVKLSSKQVKEINAQKIV 680
>gi|119395709 coagulation factor XIII A1 subunit precursor [Homo
sapiens]
Length = 732
Score = 398 bits (1022), Expect = e-110
Identities = 243/710 (34%), Positives = 374/710 (52%), Gaps = 40/710 (5%)
Query: 4 IRVTKVDWQRSR---NGAAHHTQEYPCPELVVRRGQSFSLTLELSRALDCEEILI---FT 57
+ VT V + R N HHT +Y +L+VRRGQSF + ++ SR D L +
Sbjct: 46 LNVTSVHLFKERWDTNKVDHHTDKYENNKLIVRRGQSFYVQIDFSRPYDPRRDLFRVEYV 105
Query: 58 METGPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIR 117
+ P+ ++ + SEL+ G+ W A + ++++ +S+ S P ++G++ + +
Sbjct: 106 IGRYPQENKGTYIPVPI-VSELQSGK-WGAKIVMREDRSVRLSIQSSPKCIVGKFRMYVA 163
Query: 118 LSSHR---KHSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRA 174
+ + + S + +LFNPWC +D V+L +E+ER+EYVL+D G+IF G I+
Sbjct: 164 VWTPYGVLRTSRNPETDTYILFNPWCEDDAVYLDNEKEREEYVLNDIGVIFYGEVNDIKT 223
Query: 175 QGWNYGQFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVV 234
+ W+YGQFE+ IL+ CL ++DR+ D+S R NPI V+RV SAMVN+ +D GV+
Sbjct: 224 RSWSYGQFEDGILDTCLYVMDRAQ-------MDLSGRGNPIKVSRVGSAMVNAKDDEGVL 276
Query: 235 QGQWQGKYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRV 294
G W Y G P W GSV IL ++ + PV+YGQCWVFAGV T LRCLGI R+
Sbjct: 277 VGSWDNIYAYGVPPSAWTGSVDILLEY-RSSENPVRYGQCWVFAGVFNTFLRCLGIPARI 335
Query: 295 VSNFNSAHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQV 354
V+N+ SAHD D NL +D +++ G LT+DS+WN+H WNE+W R DL + GWQ
Sbjct: 336 VTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQA 395
Query: 355 LDATPQEESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVY 414
+D+TPQE S+G++RCGPASV AI+ G V D PFVFAEVN+D I +D +
Sbjct: 396 VDSTPQENSDGMYRCGPASVQAIKHGHVCFQFDAPFVFAEVNSDLIYITAKKDGTHVVEN 455
Query: 415 SNTKKIGRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIR 474
+ IG+ I TK +G D +DITD YK+ EG +ER A+ ++G + +
Sbjct: 456 VDATHIGKLIVTKQIGGDGMMDITDTYKFQEGQEEERLALETAL--MYGAKKPLNTEGVM 513
Query: 475 RAGGRCLWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQRVRVNLSGA 534
+ ++ ++ F+V E +LG D +L++ N + + LS
Sbjct: 514 K---------------SRSNVDMDFEV-ENAVLGKDFKLSITFRNNSHNRYTITAYLSAN 557
Query: 535 TILYTRKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKGE 594
YT P AE E+ V L P K+ + I +Y L E + + +
Sbjct: 558 ITFYTGVPKAEFKKETFDVTLEPLSFKKEAVLIQAGEYMGQLLEQASLHFFVTARINETR 617
Query: 595 KLLVEKDITLEDF--ITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQ 652
+L ++ T+ I IKV G +VG +TV V NPL E +++ + ++G G+ +
Sbjct: 618 DVLAKQKSTVLTIPEIIIKVRGTQVVGSDMTVTVEFTNPLKETLRNVWVHLDGPGVTRPM 677
Query: 653 LSIDVPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHV 702
+ + P + P SG R+L + S + G + V +
Sbjct: 678 KKM-FREIRPNSTVQWEEVCRPWVSGHRKLIASMSSDSLRHVYGELDVQI 726
>gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Homo
sapiens]
Length = 721
Score = 324 bits (831), Expect = 2e-88
Identities = 214/711 (30%), Positives = 352/711 (49%), Gaps = 37/711 (5%)
Query: 1 MAGIRVTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTL----ELSRALDCEEILIF 56
M + + D+Q +RN HHT+ L VRRGQ F++ L + L + +
Sbjct: 32 MDALGIKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVAL 91
Query: 57 TMETGPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSI 116
T +TG + S+ T+A F S L + W+A E + ++ T+S+ +P AVIG Y L +
Sbjct: 92 TAQTGEQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLL 151
Query: 117 RLSSHRKHSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQG 176
++S ++ LG+F LLFNPW ED VFL +E +R EY+L+ +G+I+ G I+A+
Sbjct: 152 QVSGRKQ---LLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAES 208
Query: 177 WNYGQFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQG 236
W++GQFE D++++ L +L + V P++V RV+ A+++ ++ V+
Sbjct: 209 WDFGQFEGDVIDLSLRLLSKDK--------QVEKWSQPVHVARVLGALLHFLKEQRVLPT 260
Query: 237 QWQGKYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVS 296
G RGSV IL++WL GR +PV GQ WV A V CTVLRCLGI RVV+
Sbjct: 261 PQTQATQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVT 320
Query: 297 NFNSAHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLD 356
F SA T L +D+Y + G + +W F E W R L Y+GWQ+L
Sbjct: 321 TFASAQGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILH 380
Query: 357 ATPQEESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSN 416
+ + C V A++EG + L +FA +NA + W ED + E SN
Sbjct: 381 PSAPNGGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSN 440
Query: 417 TKKIGRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIRRA 476
TK +G ISTK VGSD DIT YKYPEGS +E++V + E
Sbjct: 441 TKYVGNNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMERE----------- 489
Query: 477 GGRCLWRDDLLEPATKPSIAGKFKVLEPPM---LGHDLRLALCLANLTSRAQRVRVNLSG 533
+D+ + P + + + + +L+ P L D ++++ L N + + + V++ +
Sbjct: 490 ------KDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGV 543
Query: 534 ATILYTRKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKG 593
+ Y A++ + + L EK I I + +S ++ + E+ + L AM ++
Sbjct: 544 QAVHYNGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSES 603
Query: 594 E-KLLVEKDITL-EDFITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQE 651
++DI + + IK+ A +T V++ N L ++DC + + G GL+
Sbjct: 604 NLSCFAQEDIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHR 663
Query: 652 QLSIDVPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHV 702
+ S ++ P+ +F TP+ G ++L V++ F ++ + V V
Sbjct: 664 ERSYRFRSVWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 714
>gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Homo
sapiens]
Length = 691
Score = 323 bits (828), Expect = 3e-88
Identities = 213/706 (30%), Positives = 350/706 (49%), Gaps = 37/706 (5%)
Query: 6 VTKVDWQRSRNGAAHHTQEYPCPELVVRRGQSFSLTL----ELSRALDCEEILIFTMETG 61
+ D+Q +RN HHT+ L VRRGQ F++ L + L + + T +TG
Sbjct: 7 IKSCDFQAARNNEEHHTKALSSRRLFVRRGQPFTIILYFRAPVRAFLPALKKVALTAQTG 66
Query: 62 PRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSSH 121
+ S+ T+A F S L + W+A E + ++ T+S+ +P AVIG Y L +++S
Sbjct: 67 EQPSKINRTQATFPISSLGDRKWWSAVVEERDAQSWTISVTTPADAVIGHYSLLLQVSGR 126
Query: 122 RKHSNRRLGEFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYGQ 181
++ LG+F LLFNPW ED VFL +E +R EY+L+ +G+I+ G I+A+ W++GQ
Sbjct: 127 KQ---LLLGQFTLLFNPWNREDAVFLKNEAQRMEYLLNQNGLIYLGTADCIQAESWDFGQ 183
Query: 182 FEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQGK 241
FE D++++ L +L + V P++V RV+ A+++ ++ V+
Sbjct: 184 FEGDVIDLSLRLLSKDK--------QVEKWSQPVHVARVLGALLHFLKEQRVLPTPQTQA 235
Query: 242 YGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNSA 301
G RGSV IL++WL GR +PV GQ WV A V CTVLRCLGI RVV+ F SA
Sbjct: 236 TQEGALLNKRRGSVPILRQWLTGRGRPVYDGQAWVLAAVACTVLRCLGIPARVVTTFASA 295
Query: 302 HDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPSYNGWQVLDATPQE 361
T L +D+Y + G + +W F E W R L Y+GWQ+L +
Sbjct: 296 QGTGGRLLIDEYYNEEGLQNGEGQRGRIWIFQTSTECWMTRPALPQGYDGWQILHPSAPN 355
Query: 362 ESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKKIG 421
+ C V A++EG + L +FA +NA + W ED + E SNTK +G
Sbjct: 356 GGGVLGSCDLVPVRAVKEGTLGLTPAVSDLFAAINASCVVWKCCEDGTLELTDSNTKYVG 415
Query: 422 RCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFGVEASGRRIWIRRAGGRCL 481
ISTK VGSD DIT YKYPEGS +E++V + E
Sbjct: 416 NNISTKGVGSDRCEDITQNYKYPEGSLQEKEVLERVEKEKMERE---------------- 459
Query: 482 WRDDLLEPATKPSIAGKFKVLEPPM---LGHDLRLALCLANLTSRAQRVRVNLSGATILY 538
+D+ + P + + + + +L+ P L D ++++ L N + + + V++ + + Y
Sbjct: 460 -KDNGIRPPSLETASPLYLLLKAPSSLPLRGDAQISVTLVNHSEQEKAVQLAIGVQAVHY 518
Query: 539 TRKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKGE-KLL 597
A++ + + L EK I I + +S ++ + E+ + L AM ++
Sbjct: 519 NGVLAAKLWRKKLHLTLSANLEKIITIGLFFSNFERNPPENTFLRLTAMATHSESNLSCF 578
Query: 598 VEKDITL-EDFITIKVLGPAMVGVAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSID 656
++DI + + IK+ A +T V++ N L ++DC + + G GL+ + S
Sbjct: 579 AQEDIAICRPHLAIKMPEKAEQYQPLTASVSLQNSLDAPMEDCVISILGRGLIHRERSYR 638
Query: 657 VPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHV 702
++ P+ +F TP+ G ++L V++ F ++ + V V
Sbjct: 639 FRSVWPENTMCAKFQFTPTHVGLQRLTVEVDCNMFQNLTNYKSVTV 684
>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
Length = 352
Score = 35.4 bits (80), Expect = 0.18
Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 19/127 (14%)
Query: 1 MAGIRVTKVDWQRSRNGAAHHTQEY----------PCPELVVRRGQSFS-LTLELSR-AL 48
+ +++T+V WQ+S NG+ + Y P E V SF+ T+ LSR L
Sbjct: 57 LPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLEL 116
Query: 49 DCEEILI---FTMETGPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLAS-- 103
+ E + I T TG R S+ T T+ +E + A++ Q +K L + S
Sbjct: 117 EDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSAN 176
Query: 104 --PPSAV 108
PPS V
Sbjct: 177 GKPPSVV 183
>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
Length = 458
Score = 35.4 bits (80), Expect = 0.18
Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 19/127 (14%)
Query: 1 MAGIRVTKVDWQRSRNGAAHHTQEY----------PCPELVVRRGQSFS-LTLELSR-AL 48
+ +++T+V WQ+S NG+ + Y P E V SF+ T+ LSR L
Sbjct: 57 LPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLEL 116
Query: 49 DCEEILI---FTMETGPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLAS-- 103
+ E + I T TG R S+ T T+ +E + A++ Q +K L + S
Sbjct: 117 EDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSAN 176
Query: 104 --PPSAV 108
PPS V
Sbjct: 177 GKPPSVV 183
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 35.4 bits (80), Expect = 0.18
Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 19/127 (14%)
Query: 1 MAGIRVTKVDWQRSRNGAAHHTQEY----------PCPELVVRRGQSFS-LTLELSR-AL 48
+ +++T+V WQ+S NG+ + Y P E V SF+ T+ LSR L
Sbjct: 57 LPSVKITQVTWQKSTNGSKQNVAIYNPSMGVSVLAPYRERVEFLRPSFTDGTIRLSRLEL 116
Query: 49 DCEEILI---FTMETGPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLAS-- 103
+ E + I T TG R S+ T T+ +E + A++ Q +K L + S
Sbjct: 117 EDEGVYICEFATFPTGNRESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSAN 176
Query: 104 --PPSAV 108
PPS V
Sbjct: 177 GKPPSVV 183
>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
Length = 1646
Score = 32.3 bits (72), Expect = 1.5
Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 10/85 (11%)
Query: 530 NLSGATILYTRKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCL 589
NL+G I R+P A HE + +KR+ KED+T ++ + +
Sbjct: 780 NLAGEVIFKFRQPEA---HEKPS-------QKRVKKLRKKQGSKEDMTRSEESISSGTST 829
Query: 590 VTKGEKLLVEKDITLEDFITIKVLG 614
E++ E D +E FIT +VLG
Sbjct: 830 ARSVEEVEEENDQEMESFITEEVLG 854
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 31.2 bits (69), Expect = 3.4
Identities = 30/129 (23%), Positives = 47/129 (36%), Gaps = 23/129 (17%)
Query: 150 EEERQEYVLSDSGIIFRGVEKHIRAQGWNYGQFEEDILNICLSILDRSPGHQNNPATDVS 209
E + + +SG I + EK + GW YG F+ + + +++ P +N A
Sbjct: 742 EARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPK 801
Query: 210 CRHNP----IYVTRVISAMVNSNNDRGV------------VQGQWQGKYG-------GGT 246
P + T S ++SN V V WQ K G
Sbjct: 802 KALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSV 861
Query: 247 SPLHWRGSV 255
SP+H +G V
Sbjct: 862 SPIHGQGQV 870
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 31.2 bits (69), Expect = 3.4
Identities = 30/129 (23%), Positives = 47/129 (36%), Gaps = 23/129 (17%)
Query: 150 EEERQEYVLSDSGIIFRGVEKHIRAQGWNYGQFEEDILNICLSILDRSPGHQNNPATDVS 209
E + + +SG I + EK + GW YG F+ + + +++ P +N A
Sbjct: 769 EARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPK 828
Query: 210 CRHNP----IYVTRVISAMVNSNNDRGV------------VQGQWQGKYG-------GGT 246
P + T S ++SN V V WQ K G
Sbjct: 829 KALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSV 888
Query: 247 SPLHWRGSV 255
SP+H +G V
Sbjct: 889 SPIHGQGQV 897
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 31.2 bits (69), Expect = 3.4
Identities = 30/129 (23%), Positives = 47/129 (36%), Gaps = 23/129 (17%)
Query: 150 EEERQEYVLSDSGIIFRGVEKHIRAQGWNYGQFEEDILNICLSILDRSPGHQNNPATDVS 209
E + + +SG I + EK + GW YG F+ + + +++ P +N A
Sbjct: 769 EARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPK 828
Query: 210 CRHNP----IYVTRVISAMVNSNNDRGV------------VQGQWQGKYG-------GGT 246
P + T S ++SN V V WQ K G
Sbjct: 829 KALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSV 888
Query: 247 SPLHWRGSV 255
SP+H +G V
Sbjct: 889 SPIHGQGQV 897
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 30.8 bits (68), Expect = 4.5
Identities = 20/84 (23%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 51 EEILIFTMETGPRASEALHTKAVFQTSELERGEGWTAAREAQMEKTLTVSLASPPSAVIG 110
E+ +++ + + P +SE H K + + E E W A + ++ TLT + SA +
Sbjct: 83 EDGMVYAVRSFPLSSE--HAKFLIYAQDKETQEKWQVAVKLSLKPTLTEE-SVKESAEVE 139
Query: 111 RYLLSIRLSSHRKHSNRRLGEFVL 134
+ + S H H R+ ++V+
Sbjct: 140 EIVFPRQFSKHSGHLQRQKRDWVI 163
>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform 2
precursor [Homo sapiens]
Length = 1452
Score = 30.8 bits (68), Expect = 4.5
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 7/86 (8%)
Query: 383 HLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKKIGRCISTKAVGSDSRVDITDLYK 442
++A GP E D+ +WHE+ + + +N ++GR K D T++YK
Sbjct: 968 YIATQGPM--QETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDD-----TEIYK 1020
Query: 443 YPEGSRKERQVYSKAVNRLFGVEASG 468
+ + E ++ ++ V R F VE G
Sbjct: 1021 DIKVTLIETELLAEYVIRTFAVEKRG 1046
>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform 1
precursor [Homo sapiens]
Length = 1465
Score = 30.8 bits (68), Expect = 4.5
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 7/86 (8%)
Query: 383 HLAHDGPFVFAEVNADYITWLWHEDESRERVYSNTKKIGRCISTKAVGSDSRVDITDLYK 442
++A GP E D+ +WHE+ + + +N ++GR K D T++YK
Sbjct: 981 YIATQGPM--QETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWPDD-----TEIYK 1033
Query: 443 YPEGSRKERQVYSKAVNRLFGVEASG 468
+ + E ++ ++ V R F VE G
Sbjct: 1034 DIKVTLIETELLAEYVIRTFAVEKRG 1059
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,525,524
Number of Sequences: 37866
Number of extensions: 1251196
Number of successful extensions: 2464
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2399
Number of HSP's gapped (non-prelim): 25
length of query: 706
length of database: 18,247,518
effective HSP length: 109
effective length of query: 597
effective length of database: 14,120,124
effective search space: 8429714028
effective search space used: 8429714028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.