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Search of human proteins with 148612879
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148612879 polyhomeotic like 3 [Homo sapiens]
(995 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148612879 polyhomeotic like 3 [Homo sapiens] 1953 0.0
gi|62953127 polyhomeotic 1-like [Homo sapiens] 294 3e-79
gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens] 285 1e-76
gi|37595530 polyhomeotic-like 2 isoform b [Homo sapiens] 245 2e-64
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 97 1e-19
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ... 83 1e-15
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [... 83 1e-15
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 83 1e-15
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 80 1e-14
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 80 1e-14
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 80 1e-14
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 79 2e-14
gi|151301154 mucin 6, gastric [Homo sapiens] 77 1e-13
gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo sa... 75 3e-13
gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo sap... 74 5e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 74 7e-13
gi|32699038 sterile alpha motif domain containing 7 [Homo sapiens] 74 7e-13
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 73 2e-12
gi|91982772 mucin 17 [Homo sapiens] 72 3e-12
gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens] 71 6e-12
gi|38788274 bromodomain PHD finger transcription factor isoform ... 69 2e-11
gi|56549696 E1A binding protein p400 [Homo sapiens] 69 2e-11
gi|5174669 sex comb on midleg-like 2 [Homo sapiens] 69 2e-11
gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens] 69 3e-11
gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens] 68 4e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is... 67 1e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 66 2e-10
gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens] 65 3e-10
gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens] 65 3e-10
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 65 4e-10
>gi|148612879 polyhomeotic like 3 [Homo sapiens]
Length = 995
Score = 1953 bits (5059), Expect = 0.0
Identities = 995/995 (100%), Positives = 995/995 (100%)
Query: 1 MAEAEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQ 60
MAEAEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQ
Sbjct: 1 MAEAEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQ 60
Query: 61 VIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRP 120
VIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRP
Sbjct: 61 VIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRP 120
Query: 121 STSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTA 180
STSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTA
Sbjct: 121 STSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTA 180
Query: 181 SQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSS 240
SQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSS
Sbjct: 181 SQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSS 240
Query: 241 SQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSI 300
SQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSI
Sbjct: 241 SQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSI 300
Query: 301 HQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPP 360
HQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPP
Sbjct: 301 HQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPP 360
Query: 361 SQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQ 420
SQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQ
Sbjct: 361 SQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQ 420
Query: 421 SPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGP 480
SPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGP
Sbjct: 421 SPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGP 480
Query: 481 VQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQP 540
VQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQP
Sbjct: 481 VQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQP 540
Query: 541 EILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQV 600
EILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQV
Sbjct: 541 EILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQV 600
Query: 601 EDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSA 660
EDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSA
Sbjct: 601 EDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSA 660
Query: 661 SVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILTHVIEG 720
SVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILTHVIEG
Sbjct: 661 SVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILTHVIEG 720
Query: 721 FVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQPELQNNTKHADNSSDTEMED 780
FVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQPELQNNTKHADNSSDTEMED
Sbjct: 721 FVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQPELQNNTKHADNSSDTEMED 780
Query: 781 MIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRK 840
MIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRK
Sbjct: 781 MIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRK 840
Query: 841 PDNQSLGHRGRRPSGPDGAAREHILRQLPITYPSAEEDLASHEDSVPSAMTTRLRRQSER 900
PDNQSLGHRGRRPSGPDGAAREHILRQLPITYPSAEEDLASHEDSVPSAMTTRLRRQSER
Sbjct: 841 PDNQSLGHRGRRPSGPDGAAREHILRQLPITYPSAEEDLASHEDSVPSAMTTRLRRQSER 900
Query: 901 ERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDG 960
ERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDG
Sbjct: 901 ERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDG 960
Query: 961 QALLLLKEDHLMSAMNIKLGPALKICARINSLKES 995
QALLLLKEDHLMSAMNIKLGPALKICARINSLKES
Sbjct: 961 QALLLLKEDHLMSAMNIKLGPALKICARINSLKES 995
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 294 bits (752), Expect = 3e-79
Identities = 335/1090 (30%), Positives = 466/1090 (42%), Gaps = 193/1090 (17%)
Query: 13 MDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSS 72
M+TE ++S + ++SS SSR Q Q+S+Y +R AVQ +Q AL R P++
Sbjct: 1 METESEQNSNSTNGSSSSG-------GSSRPQIAQMSLY---ERQAVQALQ-ALQRQPNA 49
Query: 73 AAQYLQQMYAAQQQHLMLHT-AALQQQHLSSSQL----------QSLAAVQASLSSGRPS 121
A + Q M Q + LH+ AA+QQ +++S+ Q QAS++ S
Sbjct: 50 AQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTS 109
Query: 122 TSPTGSVTQQ-SSMSQTSINLST--SPTPAQLISRSQASSSTS---GSITQQTMLLGSTS 175
+ S +Q SS S T++ S T + +++SQA G++ Q LG
Sbjct: 110 AAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNV 169
Query: 176 PTLT----------------------------ASQAQ-MYLRAQMLIFTPATTVAAVQSD 206
P + A Q Q + +R Q + Q
Sbjct: 170 PLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKA 229
Query: 207 IPV----VSSSSSSSCQSAATQVQNLTLRSQKL--------------------------- 235
IP VSS S +S Q+ A + +Q L
Sbjct: 230 IPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHG 289
Query: 236 --GVLSSSQNG----PPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLES 289
G L SS G P K T Q L TVT S+ SQ + + KK E+
Sbjct: 290 GLGQLPSSGMGGGSCPRKGTGVVQPLPAAQ---TVTVSQGSQTEAESAAAKKAEADGSGQ 346
Query: 290 RSTAV--TRTSS---IHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLIL---QQ 341
++ + TRT++ LI+ A+Y+ IQPHSLI+ QQ +H +V Q I QQ
Sbjct: 347 QNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQ-QIHLQQKQVVIQQQIAIHHQQ 405
Query: 342 QQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQS 401
Q Q Q L +T Q Q P P Q P+ V P+QS
Sbjct: 406 QFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQ-QVPPSQS 464
Query: 402 QSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQ 461
Q Q++VV P SP P P A +P P+ + P ++ + +A
Sbjct: 465 QQQAQTLVVQPMLQSSPLSLP-----PDAAPKP-PIPIQSKPPVAPIKPPQLGAAKMSAA 518
Query: 462 LNLPSHLPLPASPVVHIGPVQQSAL-VSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTS 520
P H+P+ G Q AL ++ V S ++QS +AS P S +
Sbjct: 519 QQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQA 578
Query: 521 PPA--QIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLP-PP 577
P A + PP M VQ V+ A S + A + LP P
Sbjct: 579 PGALQECPPTLAPGMTLAPVQ----GTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKP 634
Query: 578 QTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRG 637
QT+AV + EEE + S + P SP
Sbjct: 635 QTLAVKRKADS----------------EEERDDVSTLGSMLPAKASPVAESPKV------ 672
Query: 638 EDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSI 697
+ + L E+ E +VA+V+A+ +PS P P + P T S M S
Sbjct: 673 --MDEKSSLGEKAE--SVANVNAN---TPSSELVALTPAPSV--PPPTLAMVSRQMGDS- 722
Query: 698 PSIENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSV 757
KPPQAIVKPQILTH+IEGFVIQEG EPFPV S LL E ++PL
Sbjct: 723 -----KPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKES---EKPL--------- 765
Query: 758 CVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCT 817
Q L + ++ AE + + LLKCE+CGK A +F SKRFC+
Sbjct: 766 --QTGLPTGLTENQSGGPLGVDSPSAEL---DKKANLLKCEYCGKYAPAEQFRGSKRFCS 820
Query: 818 MSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPDGAAREHILRQLPITYPSAEE 877
M+CAKRYNVSCS +F L R K ++ R RR GP ++ + ++ +E
Sbjct: 821 MTCAKRYNVSCSHQFRLKRKKMKEFQEANYARVRR-RGPRRSSSDIARAKIQGKCHRGQE 879
Query: 878 DLASHEDSV----------PSAMTTRLRRQSERERERELRDVRIRK-MPENSDLLPV-AQ 925
D + D+ P ++ R ER+L + PE + PV
Sbjct: 880 DSSRGSDNSSYDEALSPTSPGPLSVRAGHG-----ERDLGNPNTAPPTPELHGINPVFLS 934
Query: 926 TEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKI 985
+ PS W+V++V+ FI SL GCQ+IA+EFR+QEIDGQALLLLKE+HLMSAMNIKLGPALKI
Sbjct: 935 SNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKI 994
Query: 986 CARINSLKES 995
CA+IN LKE+
Sbjct: 995 CAKINVLKET 1004
>gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens]
Length = 858
Score = 285 bits (729), Expect = 1e-76
Identities = 290/924 (31%), Positives = 413/924 (44%), Gaps = 120/924 (12%)
Query: 116 SSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTS 175
SS +TS T + S + +S S PT Q+ S + + QQ +
Sbjct: 11 SSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQAL---HRQ 67
Query: 176 PTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKL 235
P+ A Q AQ T AA+Q SS+ QS A VQ +L S +
Sbjct: 68 PSTAAQYLQQMYAAQQQHLMLQT--AALQQQ-----HLSSAQLQSLAA-VQQASLVSNRQ 119
Query: 236 GVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVT 295
G S S N ++ +Q+ S+ + + +Q S ++ + L +++
Sbjct: 120 GSTSGS-NVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPA 178
Query: 296 RTSSIHQLIAPASYSPIQPHSLIKHQQIPLHS-----PPSKVSHHQLILQQQQQQIQPIT 350
T+S Q+ A P + + Q L + PP+ L L+ QQ +
Sbjct: 179 LTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAAS 238
Query: 351 LQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQH---CSPIQSHP--SPLTVSPNQSQSAQ 405
TQ PS P G P P+ AQS++ SP + P + + P++
Sbjct: 239 GPTPTQPVLPSLALKPTPG-GSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGN 297
Query: 406 QSVVVSPPPPHSPSQS-PTIIIHP-----QALIQPHPLV----SSALQPGPNLQQSTANQ 455
SV S S++ P + HP A +QPH L+ S LQP +QQ Q
Sbjct: 298 SSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQ 357
Query: 456 VQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPP 515
Q P + PV+ P Q A VSP S + Q S + P+ +P
Sbjct: 358 QQQPP--------PQQSRPVLQAEPHPQLASVSP-----SVALQPSSEAHAMPLGPVTP- 403
Query: 516 QMSTSPPAQIPPLPLQSMQ-SLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTL 574
+ P Q P L S Q P G QN E +P Q FQ
Sbjct: 404 ----ALPLQCPTANLHKPGGSQQCHPPTPDTGP---QNG--HPEGVPHTP---QRRFQ-- 449
Query: 575 PPPQTVAVNLQVQPPAPVDPPVVYQVEDVC--EEEMPEESDECVRMDRTPPPPTLSPAAI 632
T AV LQ+QP +P V ++V E+ +PE R+ P P
Sbjct: 450 ---HTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPET--------RSGPSPHQQAIVT 498
Query: 633 TVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTS 692
+ G + P ++ ++ + +D S + + S S+
Sbjct: 499 AMPGGLPV----PTSPNIQPSPAHETGQGIVHALTDLSSPG-------MTSGNGNSASSI 547
Query: 693 MHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQ 752
++ + ENKPPQAIVKPQILTHVIEGFVIQEG EPFPV RSSLL+ KK
Sbjct: 548 AGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKY------ 601
Query: 753 VINSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLRS 812
+ PE H ++D+EME+ +E+ EE LKCE CG++ +A +F RS
Sbjct: 602 ---AQGFLPEKLPQQDHT-TTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRS 657
Query: 813 KRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQS--LGHRGRRPSG-------------PD 857
KRFC+M+CAKRYNV C+K+ L +R ++ H RR S P
Sbjct: 658 KRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPT 717
Query: 858 GAAREHILRQLPITYPSAEE----DLASHEDSV-PSAMTTRLRRQSERERERELRDVRIR 912
G + L +T+ + D +S+E+ + P + ++ R+ + +R+ EL D+ +R
Sbjct: 718 GTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMR 777
Query: 913 KMPE-NSDLLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHL 971
+ LP +EP+ W V+DV+ FI SLPGCQ+IA+EFRAQEIDGQALLLLKEDHL
Sbjct: 778 DLVGMGHHFLP---SEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHL 834
Query: 972 MSAMNIKLGPALKICARINSLKES 995
MSAMNIKLGPALKI ARI+ LK+S
Sbjct: 835 MSAMNIKLGPALKIYARISMLKDS 858
Score = 261 bits (668), Expect = 2e-69
Identities = 217/554 (39%), Positives = 286/554 (51%), Gaps = 92/554 (16%)
Query: 17 PNPGTSSVSTTTSSTTTTTITTS--------SSRMQQPQISVYSG-SDRHAVQVIQQALH 67
P P TSS + TSST+ + ++ S R PQISVYSG DR VQVIQQALH
Sbjct: 6 PVPHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALH 65
Query: 68 RPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAV-QASLSSGRPSTSPTG 126
R PS+AAQYLQQMYAAQQQHLML TAALQQQHLSS+QLQSLAAV QASL S R ++
Sbjct: 66 RQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGS 125
Query: 127 SVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGS-ITQQTMLLGST-SPTLTASQAQ 184
+V+ Q+ +SINL+ SP AQL++R+Q+ +S + S I QQ +LLG+T SP LTASQAQ
Sbjct: 126 NVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQ 185
Query: 185 MYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNG 244
MYLRAQMLIFTP TVA VQ ++ + S + QVQNLTLR+Q+ ++S
Sbjct: 186 MYLRAQMLIFTPTATVATVQPEL----GTGSPARPPTPAQVQNLTLRTQQTPAAAASGPT 241
Query: 245 PPKSTSQTQSL-----------TICHNKTTVTSSKISQR----DPSPESNKKGES----- 284
P + + +L T ++ T +S + D E +KKG+
Sbjct: 242 PTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVP 301
Query: 285 PSLESRSTAVTRT---SSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQ 341
S+E R+ ++RT + H LIAPA Y+ +QPH L L P SK Q ++QQ
Sbjct: 302 GSMEGRA-GLSRTVPAVAAHPLIAPA-YAQLQPHQL-------LPQPSSKHLQPQFVIQQ 352
Query: 342 QQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPN-- 399
Q Q Q Q PPP Q LQ + HP +VSP+
Sbjct: 353 QPQPQQ--------QQPPPQQSRPVLQ------------------AEPHPQLASVSPSVA 386
Query: 400 -QSQSAQQSVVVSPPPPHSPSQSPTIIIH-PQALIQPH-PLVSSALQPG--PNLQQSTAN 454
Q S ++ + P P P Q PT +H P Q H P + Q G + +
Sbjct: 387 LQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQR 446
Query: 455 QVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIV-------SPSHQQYSSLQSS 507
+ Q T+ + L PASP P V+PG++ V SP Q +
Sbjct: 447 RFQHTSAVILQLQ---PASPPQQCVPDDWKE-VAPGEKSVPETRSGPSPHQQAIVTAMPG 502
Query: 508 PIPIASPPQMSTSP 521
+P+ + P + SP
Sbjct: 503 GLPVPTSPNIQPSP 516
>gi|37595530 polyhomeotic-like 2 isoform b [Homo sapiens]
Length = 323
Score = 245 bits (625), Expect = 2e-64
Identities = 150/316 (47%), Positives = 195/316 (61%), Gaps = 34/316 (10%)
Query: 701 ENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQ 760
ENKPPQAIVKPQILTHVIEGFVIQEG EPFPV RSSLL+ KK +
Sbjct: 21 ENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKY---------AQGFL 71
Query: 761 PELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLRSKRFCTMSC 820
PE H ++D+EME+ +E+ EE LKCE CG++ +A +F RSKRFC+M+C
Sbjct: 72 PEKLPQQDHT-TTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRFCSMAC 130
Query: 821 AKRYNVSCSKKFALSRWNRKPDNQS--LGHRGRRPSG-------------PDGAAREHIL 865
AKRYNV C+K+ L +R ++ H RR S P G +
Sbjct: 131 AKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTVPLSVT 190
Query: 866 RQLPITYPSAEE----DLASHEDSV-PSAMTTRLRRQSERERERELRDVRIRKMPE-NSD 919
L +T+ + D +S+E+ + P + ++ R+ + +R+ EL D+ +R +
Sbjct: 191 AALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHH 250
Query: 920 LLPVAQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKL 979
LP +EP+ W V+DV+ FI SLPGCQ+IA+EFRAQEIDGQALLLLKEDHLMSAMNIKL
Sbjct: 251 FLP---SEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKL 307
Query: 980 GPALKICARINSLKES 995
GPALKI ARI+ LK+S
Sbjct: 308 GPALKIYARISMLKDS 323
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 96.7 bits (239), Expect = 1e-19
Identities = 174/724 (24%), Positives = 260/724 (35%), Gaps = 113/724 (15%)
Query: 12 AMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQA---LHR 68
A P P T + SS + + TT S + + S G R A + + + L
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHS-TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251
Query: 69 PPSS--AAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTG 126
P S +A+ + A Q AL+ ++ + + A+ SS + SP+G
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG 311
Query: 127 SVTQQ---SSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQA 183
+ + + T + + P+P A S S + QT+ + P SQA
Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL---PSPPATPPSQA 368
Query: 184 QMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQN 243
+ TP IP + S + S L L S + +++
Sbjct: 369 PPSMT------TPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ----ATTSL 418
Query: 244 GPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLE---SRSTAVTRTSSI 300
G P + LT+ +T + S PS ++ +SP L+ S + +S+
Sbjct: 419 GSPTLQATHSFLTMSPRQT-----QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSL 473
Query: 301 HQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQN---STQD 357
++P S SP+ H L + HSP + +S + + Q + P +LQ S
Sbjct: 474 SPAVSPLS-SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532
Query: 358 PP----PSQHCIPLQNHGLPPAPSNAQSQHCS---PIQSHPSPLTVSPNQSQSAQQSVVV 410
PP PS PLQ P + ++ C P+Q+ PSPLT P ++ S+ +
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSS----IA 588
Query: 411 SPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPL 470
+PPP Q+P + P P P +S P P QA L LP PL
Sbjct: 589 TPPP-----QAPPALASPPLQGLPSPPLSPLATPPP----------QAPPXLALP---PL 630
Query: 471 PASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPP-QMSTSPPAQIPPLP 529
A P P S L +P Q +P+ LQ+ P SPP Q SPPA P
Sbjct: 631 QAPPSPPASP-PLSPLATPSPQ--APNALAVHLLQAPFSPPPSPPVQAPFSPPASPP--- 684
Query: 530 LQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPP 589
VS P ++A PP A LQV P
Sbjct: 685 -------------------------VSPSATPPSQA----------PPSLAAPPLQVPPS 709
Query: 590 APVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQ 649
P PP+ + P + P P +SP+A R L + PL
Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP 769
Query: 650 VELPAVASVSASVIKSPSDPSHVSVPP------PPLLLPAATTRSNSTSMHSSIPSIENK 703
PA +S P P ++ PP PP P S S S+ S +
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS--PLATP 827
Query: 704 PPQA 707
PPQA
Sbjct: 828 PPQA 831
Score = 84.0 bits (206), Expect = 7e-16
Identities = 152/667 (22%), Positives = 242/667 (36%), Gaps = 109/667 (16%)
Query: 120 PSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTS-GSITQQTMLLGSTSPTL 178
P ++P T+ + S S N ++ P + R+ + +TS G ++ G+T P
Sbjct: 71 PESAPRAGPTRSAGTS--SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG- 127
Query: 179 TASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVL 238
Q + + A+ + T A +S + + +S + T + RS+ G
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG-PTPGTPSPAMARRSRAAGTE 186
Query: 239 SSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKG------ESPSLESRST 292
P +++ + T K+ ++S+ S +PSP + ++ + P+ S S+
Sbjct: 187 VGLPR--PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 293 AVTRTSSIHQL--------IAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQ 344
+ T SS + APA S +P L + + P +PP K + L
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGL-QALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 345 QIQPITLQNSTQD-PPPSQHCIPLQNHGLPPAPSNAQSQHCSP--------IQSHPSPLT 395
P + PPP PL LPP+P A +P +Q+ PSP
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLP-ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362
Query: 396 VSPNQSQSAQQSVVVSPPPPHS---PSQSPTIIIHPQALIQPHPLVSSALQP-----GPN 447
P+Q+ + + + PP P Q P + P P PL S+LQ P
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422
Query: 448 LQQS----TANQVQATAQLNLPSH--------------LPLPASPVVH------IGPVQQ 483
LQ + T + Q A L PS L LPASP + + P+
Sbjct: 423 LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS 482
Query: 484 SALVSPGQQIVS-PSHQQYSSLQSSPIP------IASPPQMSTSPPAQIPPLPLQSMQSL 536
+ P Q + S SH + L S +P +PP + T PPA + PL+++ SL
Sbjct: 483 PLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT-PPASLTTPPLENLPSL 541
Query: 537 QVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPP--PQTVAVNLQVQPPAPVDP 594
P + + + P P T PP P ++A PPA P
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601
Query: 595 PVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPA 654
P+ + P P LSP A + + PL PA
Sbjct: 602 PL-----------------------QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638
Query: 655 VASVSASVIKSPSDPSHVSV----------PPPPLLLPAATTRSNSTSMHSSIPSIENKP 704
+S SP P+ ++V P PP+ P + S S ++ PS P
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS--QAP 696
Query: 705 PQAIVKP 711
P P
Sbjct: 697 PSLAAPP 703
Score = 77.0 bits (188), Expect = 8e-14
Identities = 151/638 (23%), Positives = 219/638 (34%), Gaps = 110/638 (17%)
Query: 12 AMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPS 71
++ T P+P + S S TT + S P I V + +L PPS
Sbjct: 353 SLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS-------LTSPSLQAPPS 405
Query: 72 SAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSS-GRPSTSPTGSVTQ 130
A ++ Q L + LQ H S S QASL+S RP+++P S
Sbjct: 406 PLA------LSSLQATTSLGSPTLQATH--SFLTMSPRQTQASLTSPSRPASTPPDSPPL 457
Query: 131 QSSMS-------QTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQA 183
Q+ +S QTS++ + SP + L + S+ S + Q L P L +
Sbjct: 458 QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL---ET 514
Query: 184 QMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQN 243
Q L L PA+ ++P S + Q+A+ + L + Q
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLP---SLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571
Query: 244 GPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQL 303
P T+ T S I+ P P++ SP L+ + + L
Sbjct: 572 PPSPLTTPPPE----------TPSSIAT--PPPQAPPALASPPLQGLPSP-----PLSPL 614
Query: 304 IAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQH 363
P +P P + Q P P S Q + L + PPPS
Sbjct: 615 ATPPPQAP--PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP- 671
Query: 364 CIPLQNHGLPPAPSNAQSQHCSPIQSHPS----PLTVSPNQSQSAQQSVVVSPPPPHSPS 419
P+Q PPA P Q+ PS PL V P+ S S +PPP P
Sbjct: 672 --PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP- 728
Query: 420 QSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIG 479
PL + LQ P+ S AT +P PL A+P + +
Sbjct: 729 ----------------PLAAPPLQVPPSPPASPPMSPSATPPPRVP---PLLAAPPLQVP 769
Query: 480 PVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPP-QMSTSPPAQIP-PLPLQSMQSLQ 537
P ++L P + P Q +P +A+PP Q SPPA P P SL
Sbjct: 770 PSPPASL--PMSPLAKPPPQ-------APPALATPPLQALPSPPASFPGQAPFSPSASLP 820
Query: 538 VQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVV 597
+ P P A ++ P +PP + LQ AP PP
Sbjct: 821 MSPLATPP---------------PQAPPVLAAPLLQVPPSPPASPTLQ----APRRPPTP 861
Query: 598 YQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVG 635
V + PPPP+ SP++ G
Sbjct: 862 GPDTSVSGPRL-----TLALAPGPPPPPSRSPSSTLSG 894
>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
Length = 898
Score = 83.2 bits (204), Expect = 1e-15
Identities = 156/658 (23%), Positives = 236/658 (35%), Gaps = 108/658 (16%)
Query: 75 QYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSL----------AAVQASLSSGRPSTSP 124
Q QQ+ QQQ L LQQQ L QL L A + ++S G P P
Sbjct: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
Query: 125 TGSVTQQSSMSQTSINLSTSPTPAQLISRSQA-SSSTSGSITQQTMLLGSTSPTLTASQA 183
+ + S+ + A L+ + Q T T G T PT T
Sbjct: 65 QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT--AGLTMPTATLGNL 122
Query: 184 QMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGV------ 237
+ Y A + P+ T P +++ + AT+ Q+L L +GV
Sbjct: 123 RGYGMASPGLAAPSLTP-------PQLATPNLQQFFPQATR-QSL-LGPPPVGVPMNPSQ 173
Query: 238 LSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRT 297
+ S P K + S T ++ + + + PE +++ P +++
Sbjct: 174 FNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE------ 227
Query: 298 SSIHQLIAPASYSPIQPHSLIKHQQIPLHSP-PSKVSHHQLILQQQQQQIQPITLQNSTQ 356
Q + P P + K ++ P P P + S +L ++ + +P T+
Sbjct: 228 ---DQDLPPC------PEDIAKEKRTPAPEPEPCEAS--ELPAKRLRSSEEP------TE 270
Query: 357 DPPPSQHCIPLQNHGLPPAPSNAQSQHCSP--IQSHPSPLTVSPNQSQSAQQSVVVSPPP 414
PP Q + Q P Q+ P +++ P AQ P
Sbjct: 271 KEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI 330
Query: 415 PHSPSQ-SPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPAS 473
P + +Q P + Q P LV Q P LQQ Q Q Q+ +H
Sbjct: 331 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQ---- 386
Query: 474 PVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSM 533
GP Q QQ P Q +Q PQ + PP Q+ L LQ
Sbjct: 387 -----GPRQVQL-----QQEAEPLKQVQPQVQ---------PQAHSQPPRQV-QLQLQKQ 426
Query: 534 QSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVD 593
Q P++ +Q Q VQ +E P A+ VQ P QT P T QV AP
Sbjct: 427 VQTQTYPQVHTQAQPSVQ-----PQEHPPAQVSVQPPEQTHEQPHT---QPQVSLLAPEQ 478
Query: 594 PPVVYQVEDVCEEEMPEESDEC-VRMDRTPPPP-----------TLSPAAITVGRGEDLT 641
PVV VC EMP ++ E M++T P P S + VG E+
Sbjct: 479 TPVVVH---VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 535
Query: 642 SEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPS 699
E P + A S+ ++++S + +VP P +P + +ST +S PS
Sbjct: 536 REMPGV----WGAGGSLKVTILQSSDSRAFSTVPLTP--VPRPSDSVSSTPAATSTPS 587
>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
Length = 898
Score = 83.2 bits (204), Expect = 1e-15
Identities = 156/658 (23%), Positives = 236/658 (35%), Gaps = 108/658 (16%)
Query: 75 QYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSL----------AAVQASLSSGRPSTSP 124
Q QQ+ QQQ L LQQQ L QL L A + ++S G P P
Sbjct: 5 QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
Query: 125 TGSVTQQSSMSQTSINLSTSPTPAQLISRSQA-SSSTSGSITQQTMLLGSTSPTLTASQA 183
+ + S+ + A L+ + Q T T G T PT T
Sbjct: 65 QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT--AGLTMPTATLGNL 122
Query: 184 QMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGV------ 237
+ Y A + P+ T P +++ + AT+ Q+L L +GV
Sbjct: 123 RGYGMASPGLAAPSLTP-------PQLATPNLQQFFPQATR-QSL-LGPPPVGVPMNPSQ 173
Query: 238 LSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRT 297
+ S P K + S T ++ + + + PE +++ P +++
Sbjct: 174 FNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE------ 227
Query: 298 SSIHQLIAPASYSPIQPHSLIKHQQIPLHSP-PSKVSHHQLILQQQQQQIQPITLQNSTQ 356
Q + P P + K ++ P P P + S +L ++ + +P T+
Sbjct: 228 ---DQDLPPC------PEDIAKEKRTPAPEPEPCEAS--ELPAKRLRSSEEP------TE 270
Query: 357 DPPPSQHCIPLQNHGLPPAPSNAQSQHCSP--IQSHPSPLTVSPNQSQSAQQSVVVSPPP 414
PP Q + Q P Q+ P +++ P AQ P
Sbjct: 271 KEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI 330
Query: 415 PHSPSQ-SPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPAS 473
P + +Q P + Q P LV Q P LQQ Q Q Q+ +H
Sbjct: 331 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQ---- 386
Query: 474 PVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSM 533
GP Q QQ P Q +Q PQ + PP Q+ L LQ
Sbjct: 387 -----GPRQVQL-----QQEAEPLKQVQPQVQ---------PQAHSQPPRQV-QLQLQKQ 426
Query: 534 QSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVD 593
Q P++ +Q Q VQ +E P A+ VQ P QT P T QV AP
Sbjct: 427 VQTQTYPQVHTQAQPSVQ-----PQEHPPAQVSVQPPEQTHEQPHT---QPQVSLLAPEQ 478
Query: 594 PPVVYQVEDVCEEEMPEESDEC-VRMDRTPPPP-----------TLSPAAITVGRGEDLT 641
PVV VC EMP ++ E M++T P P S + VG E+
Sbjct: 479 TPVVVH---VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 535
Query: 642 SEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPS 699
E P + A S+ ++++S + +VP P +P + +ST +S PS
Sbjct: 536 REMPGV----WGAGGSLKVTILQSSDSRAFSTVPLTP--VPRPSDSVSSTPAATSTPS 587
>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
Length = 1073
Score = 82.8 bits (203), Expect = 1e-15
Identities = 171/708 (24%), Positives = 284/708 (40%), Gaps = 145/708 (20%)
Query: 87 HLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPST------SPTGSVTQQSSMSQTSIN 140
H + H LQ H S + A AS++ G PS+ S TGS + ++ TS
Sbjct: 224 HQIHHGHHLQHGHHHPSHV---AVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSA- 279
Query: 141 LSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTV 200
+S+S +PA +++ +A S+T G +G S T T++ + + A + F P T
Sbjct: 280 VSSSGSPASVMTNMRAPSTTGG--------IGINSVTGTSTVNNVNITA-VGSFNPNVT- 329
Query: 201 AAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQ------- 253
S + V+ S+S+ +A V + +LS NG S++
Sbjct: 330 ---SSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAA 386
Query: 254 -----SLTICHNKTTVTSS--KISQRDPSPESNKKGESPSLE--SRSTAVTRTSS--IHQ 302
S++ + TV +S ++ + D S E KKG E + AV T I++
Sbjct: 387 GMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINK 446
Query: 303 LIAPASYSPIQPHSLIKHQQ-IPLHSPPSKVSHH------------QLILQQQQQQ---- 345
++ +PI+ S + + S S +SH+ +++QQQQQQ
Sbjct: 447 VVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQ 506
Query: 346 -----IQPITLQNS------------------------TQDPPPSQHCIPLQNHGLPPAP 376
+Q +TLQ +Q SQ Q GL P P
Sbjct: 507 QQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVP 566
Query: 377 SNAQSQHCSPIQSHPSPLTVSPNQSQSAQQ---SVVVSPPPPHS----PSQSPTIIIHPQ 429
A + IQ PSP+ V S QQ S + P P+S P Q+P P
Sbjct: 567 LQATMSAATGIQ--PSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPP 624
Query: 430 ALI---QPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSAL 486
+ Q P+VS+ + PG +++ T N PAS V P+ Q+A+
Sbjct: 625 QQLQYGQQQPMVSTQMAPG-HVKSVTQN----------------PASEYVQQQPILQTAM 667
Query: 487 VSPGQQIVSPSHQQYSSLQSSPIPIASPP--QMSTSPPAQIPPLPL-QSMQSLQVQPEIL 543
S GQ PS + ++ IP+A P Q+ P A +P P S+Q + P +
Sbjct: 668 -SSGQ----PSSAGVGA-GTTVIPVAQPQGIQLPVQPTA-VPAQPAGASVQPVGQAPAAV 720
Query: 544 SQGQVLVQNALVSEE-ELPAAEALVQLPFQTLPP---PQTVAVNLQVQPPAPVDPPVVYQ 599
S Q A + ++ +P A VQ P +PP Q + QV PPA +++Q
Sbjct: 721 SAVPTGSQIANIGQQANIPTA---VQQPSTQVPPSVIQQGAPPSSQVVPPAQTG--IIHQ 775
Query: 600 VEDVCEEEMPEE---SDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVA 656
+P++ + + + P P + P A + ++ + P + LP+ +
Sbjct: 776 GVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGI-----VSQQLPAVS--SLPSAS 828
Query: 657 SVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKP 704
S+S + S + PS + P L+ P ++ +T + + S+ P
Sbjct: 829 SISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPP 876
Score = 62.0 bits (149), Expect = 3e-09
Identities = 118/505 (23%), Positives = 183/505 (36%), Gaps = 49/505 (9%)
Query: 24 VSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAA 83
V++ ST+ +++++S S + SV SG V+QQ QQ
Sbjct: 458 VTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQ------------QQQQQQ 505
Query: 84 QQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLST 143
QQQ L LQQ S+ QS+ AV S + S +Q+ S Q
Sbjct: 506 QQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQ---GL 562
Query: 144 SPTPAQ-LISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQM-YLRAQMLIFTPATTVA 201
P P Q +S + + ++ T LG + +Q Q+ Y +A + TP
Sbjct: 563 QPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAP 622
Query: 202 AVQ-----SDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLT 256
Q P+VS+ + + TQ Q+ + ++ +G P S T
Sbjct: 623 PPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTT 682
Query: 257 IC------HNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYS 310
+ + V + + + G++P+ S ++ ++I Q A +
Sbjct: 683 VIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQ-ANIPTA 741
Query: 311 PIQPHSLIKHQQIPLHSPPSK--VSHHQL-ILQQQQQQIQPITLQNSTQDPPPSQHCIPL 367
QP + + I +PPS V Q I+ Q Q P Q S +P
Sbjct: 742 VQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPP 801
Query: 368 QNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIH 427
Q G+ P SQ + S PS ++S S V S P PS +PT ++
Sbjct: 802 QPQGVEPVAQGIVSQQLPAVSSLPSASSISVT-------SQVSSTGPSGMPS-APTNLVP 853
Query: 428 PQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALV 487
PQ + Q + A Q G NL QS + NLP +P S QS
Sbjct: 854 PQNIAQ-----TPATQNG-NLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSA---QSLAQ 904
Query: 488 SPGQQIVSPSHQQYSSLQSSPIPIA 512
+ G QI SL P I+
Sbjct: 905 AIGSQIEDARRAAEPSLVGLPQTIS 929
Score = 50.1 bits (118), Expect = 1e-05
Identities = 175/785 (22%), Positives = 287/785 (36%), Gaps = 138/785 (17%)
Query: 18 NPGTSSVSTTTSSTTTTTITTSSSRMQQP------QISVYSGSDRHAVQVIQQALHRPPS 71
NP +S + +T+ I +++ P +++ SG + A+ P+
Sbjct: 325 NPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISS-SAAVSSVPN 383
Query: 72 SAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSP----TGS 127
+AA ++QQQ ++T+ + L SS GR + + +
Sbjct: 384 AAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSS--------EPFKKGRWTCTEFYEKENA 435
Query: 128 VTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGS-----ITQQTMLLGST---SPTLT 179
V + + + P ++ S +++S +S S ++ T +GS +PT+
Sbjct: 436 VPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVV 495
Query: 180 ASQAQMYLRAQMLIFTPATTVAAVQS---------DIPVVSSSSSSSCQSAATQVQNLTL 230
Q Q + Q PA +Q IP VS S S QS +QVQ L
Sbjct: 496 VQQQQQQQQQQQQ--QPALQGVTLQQMDFGSTGPQSIPAVSIPQSIS-QSQISQVQ---L 549
Query: 231 RSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPES-----NKKGESP 285
+SQ+L S Q Q L + T++++ Q PSP + + G+ P
Sbjct: 550 QSQEL------------SYQQKQGLQPVPLQATMSAATGIQ--PSPVNVVGVTSALGQQP 595
Query: 286 SLESRSTAVTRTSSIHQLIAPASYSPIQ----PHSLIKHQQIPLHSPPSKVSHHQLILQQ 341
S+ S + + + AP +P+ P L QQ P+ S H + + Q
Sbjct: 596 SISS----LAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQN 651
Query: 342 ---QQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSP--IQSHPSPLTV 396
+ Q QPI LQ + PS + +P A P + + P+ +V
Sbjct: 652 PASEYVQQQPI-LQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASV 710
Query: 397 SPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQV 456
P A S V P+ S I QA I P Q + QV
Sbjct: 711 QPVGQAPAAVSAV--------PTGSQIANIGQQANI-------------PTAVQQPSTQV 749
Query: 457 QATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQ 516
PS + A P + P Q+ ++ G Q +PS Q + S + PPQ
Sbjct: 750 P-------PSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQ 802
Query: 517 -MSTSPPAQ-IPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTL 574
P AQ I L ++ SL I QV + +P+A L
Sbjct: 803 PQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQV----SSTGPSGMPSAPT-------NL 851
Query: 575 PPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPT-LSPAAIT 633
PPQ +A Q PA + + V+ V + + + + P T S ++
Sbjct: 852 VPPQNIA-----QTPATQNGNL---VQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLA 903
Query: 634 VGRGEDLTSEHPLLEQ--VELPAVASVSASVIKSPSDPSHVSVPP-----PPLLLPAAT- 685
G + E V LP S + + + SD S S+ P +LP T
Sbjct: 904 QAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTP 963
Query: 686 --TRSNSTSMHSSIPSIENKPPQA--IVKPQILTHVIEGF-VIQEGLEPFPVSRSSLLIE 740
+ +S +S+ +I+NK QA +VK ++ V E V++E ++ S L E
Sbjct: 964 LVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQE 1023
Query: 741 QPVKK 745
+ K
Sbjct: 1024 NNLLK 1028
Score = 47.0 bits (110), Expect = 9e-05
Identities = 120/547 (21%), Positives = 196/547 (35%), Gaps = 88/547 (16%)
Query: 17 PNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSD---RHAVQVIQQALH-RPPSS 72
P T S +T + + +S+ QQP IS + A +Q L PP
Sbjct: 566 PLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQ 625
Query: 73 AAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQS 132
QY QQ Q H ++ Q +S +Q +Q ++SSG+PS++ G+ T
Sbjct: 626 QLQYGQQQPMVSTQMAPGHVKSVTQNP-ASEYVQQQPILQTAMSSGQPSSAGVGAGTTVI 684
Query: 133 SMSQTS-INLSTSPT--PAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRA 189
++Q I L PT PAQ S+ + S T SQ
Sbjct: 685 PVAQPQGIQLPVQPTAVPAQ---------PAGASVQPVGQAPAAVSAVPTGSQIANI--- 732
Query: 190 QMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKST 249
Q++IP ++ Q +TQV ++ G SSQ PP T
Sbjct: 733 ------------GQQANIP-------TAVQQPSTQVPPSVIQQ---GAPPSSQVVPPAQT 770
Query: 250 S------QTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQL 303
QT + ++ + S + P P+ + + + AV+ S +
Sbjct: 771 GIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSI 830
Query: 304 IAPASYS-------PIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQ 356
+ S P P +L+ Q I +P ++ + L+ Q QP + +T
Sbjct: 831 SVTSQVSSTGPSGMPSAPTNLVPPQNIA-QTPATQ--NGNLV----QSVSQPPLIATNTN 883
Query: 357 DPPPSQHCIPLQNHGLPPAPSNAQS--QHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPP 414
P Q IPL + A S AQ+ + P V Q+ S + +
Sbjct: 884 LPLAQQ--IPLSSTQFS-AQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSD 940
Query: 415 PHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLN-----LPSHLP 469
S S + + + P ++ +++ L G + S A+ V ++ + SHL
Sbjct: 941 GSSSSLAASASLFPLKVLP----LTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLM 996
Query: 470 LPASPVVHIGPVQQSALVSPGQQI----------VSPSH--QQYSSLQSSPIPIASPPQM 517
V + Q L+ Q+ SP Q + LQ+ P + PQ
Sbjct: 997 YAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQG 1056
Query: 518 STSPPAQ 524
+T PPAQ
Sbjct: 1057 TTQPPAQ 1063
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 79.7 bits (195), Expect = 1e-14
Identities = 121/504 (24%), Positives = 175/504 (34%), Gaps = 83/504 (16%)
Query: 208 PVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSS 267
P +S+SS+ ++ + ++ + L S++ K S T+ +K T T
Sbjct: 60 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKT-- 117
Query: 268 KISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAP-ASYSPIQPHSLIKHQQIPLH 326
Q P S +GE S +SRS +S + S SP P
Sbjct: 118 ---QEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIP------------ 162
Query: 327 SPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSP 386
SP S QQQ Q QP LQ T P P G P P+ + +
Sbjct: 163 SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP----GTPQLPTPGPTPSATA 218
Query: 387 IQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGP 446
+ P SP SQ+ Q + P PH+ Q + HPQ PHP + P P
Sbjct: 219 V-----PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL-HPQRPPSPHPPPHPS--PHP 270
Query: 447 NLQQST--ANQVQATAQLNLPSHLPLPASP--------VVHIGPVQQSALVSPGQQIVSP 496
LQ T A Q A + P H P P + H GP Q L Q +P
Sbjct: 271 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP 330
Query: 497 ------SHQQYSSLQ----SSPIPIASPPQMSTSPPAQI--------PPLPLQSMQSLQV 538
+ ++SLQ S + PP+ PPA + P P+ + + Q
Sbjct: 331 LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA 390
Query: 539 Q--PEILSQGQVLVQNALVSEEELPAAEALVQL----PFQTLPPPQTVAVNLQVQPPAPV 592
P LS NA + PA + L L P PPP + Q P +P
Sbjct: 391 HKHPPHLSGPSPFSMNANLPPP--PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 448
Query: 593 DPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVEL 652
PP + Q +++ PPP + P + + ++HP +
Sbjct: 449 QPPGLTQSQNL-----------------PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 491
Query: 653 PAVASVSASVIKSPSDPSHVSVPP 676
P S P+ P + PP
Sbjct: 492 PITPPTCPSTSTPPAGPGTSAQPP 515
Score = 62.4 bits (150), Expect = 2e-09
Identities = 109/436 (25%), Positives = 150/436 (34%), Gaps = 86/436 (19%)
Query: 212 SSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPP-----KSTSQTQSLTICHNKTTVTS 266
S S SS Q Q Q L++ GV + + PP + T S T + + T+
Sbjct: 169 SDSDSSAQQQMLQAQPPALQAPT-GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA 227
Query: 267 SKISQRDPSPES----NKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQP-------H 315
S+ + +P + ++P+L + R S H P+ + P+QP
Sbjct: 228 SQAPNQPQAPTAPVPHTHIQQAPALHPQ-----RPPSPHPPPHPSPHPPLQPLTGSAGQP 282
Query: 316 SLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPA 375
S H Q PLH H S Q P QH P Q GLPP
Sbjct: 283 SAPSHAQPPLHGQGPPGPH-------------------SLQAGPLLQHPGPPQPFGLPPQ 323
Query: 376 PSNAQSQ-HCSPIQSHPS-----PLTVSPNQSQSAQQSVVVSP---------PPPHSP-- 418
S Q+ SP ++P P + S QSQ + + P PPP +P
Sbjct: 324 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 383
Query: 419 -SQSPTIIIHPQALIQPHPLVSSA-LQPGPNLQQSTANQVQATAQLN------LPSHLPL 470
+P HP L P P +A L P P L+ ++ + +P PL
Sbjct: 384 QLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPL 443
Query: 471 PASPVVHIGPVQQSALVSP---------GQQIVSPSHQQYSSLQSSPIPIASPPQMSTSP 521
P+SP G Q L P Q P Q+ + P PI P STS
Sbjct: 444 PSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTST 503
Query: 522 PAQIPPLPLQSMQSLQVQP--EILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQT 579
P P Q S I + + EE L AE P PPP++
Sbjct: 504 PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE----PESPPPPPRS 559
Query: 580 VAVNLQVQPPAPVDPP 595
+ P VD P
Sbjct: 560 PS-----PEPTVVDTP 570
Score = 54.3 bits (129), Expect = 6e-07
Identities = 94/444 (21%), Positives = 148/444 (33%), Gaps = 37/444 (8%)
Query: 284 SPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQ 343
SPS S S+ ++ ++ + P K Q+ + S + ++
Sbjct: 59 SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADR----TSSKK 114
Query: 344 QQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQS 403
+ Q I+ NS + N P + + S S PSP + S
Sbjct: 115 TKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 174
Query: 404 AQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLN 463
AQQ ++ + PP Q+PT + P P P PGP + +
Sbjct: 175 AQQQMLQAQPP---ALQAPTGVT-PAPSSAP-PGTPQLPTPGPTPSATAVPPQGSPTASQ 229
Query: 464 LPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPA 523
P+ P +PV H +QQ+ + P Q+ S P P PP + A
Sbjct: 230 APNQPQAPTAPVPHT-HIQQAPALHP---------QRPPSPHPPPHPSPHPPLQPLTGSA 279
Query: 524 QIPPLPLQSMQSLQVQ----PEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQT 579
P P + L Q P L G +L LP + Q P T P
Sbjct: 280 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 339
Query: 580 VAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLS----PAAITVG 635
+LQ+ P + + E+ +P + M PPPT PA
Sbjct: 340 PHTSLQL----PASQSALQSQQPPREQPLPPAP---LAMPHIKPPPTTPIPQLPAPQAHK 392
Query: 636 RGEDLTSEHPLLEQVELPAVASVS-ASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMH 694
L+ P LP ++ S + + PS + PPP L+P + +S +
Sbjct: 393 HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS--AHPPPLQLMPQSQPLPSSPAQP 450
Query: 695 SSIPSIENKPPQAIVKPQILTHVI 718
+ +N PP P H +
Sbjct: 451 PGLTQSQNLPPPPASHPPTGLHQV 474
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 79.7 bits (195), Expect = 1e-14
Identities = 121/504 (24%), Positives = 175/504 (34%), Gaps = 83/504 (16%)
Query: 208 PVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSS 267
P +S+SS+ ++ + ++ + L S++ K S T+ +K T T
Sbjct: 614 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKT-- 671
Query: 268 KISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAP-ASYSPIQPHSLIKHQQIPLH 326
Q P S +GE S +SRS +S + S SP P
Sbjct: 672 ---QEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIP------------ 716
Query: 327 SPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSP 386
SP S QQQ Q QP LQ T P P G P P+ + +
Sbjct: 717 SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP----GTPQLPTPGPTPSATA 772
Query: 387 IQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGP 446
+ P SP SQ+ Q + P PH+ Q + HPQ PHP + P P
Sbjct: 773 V-----PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL-HPQRPPSPHPPPHPS--PHP 824
Query: 447 NLQQST--ANQVQATAQLNLPSHLPLPASP--------VVHIGPVQQSALVSPGQQIVSP 496
LQ T A Q A + P H P P + H GP Q L Q +P
Sbjct: 825 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP 884
Query: 497 ------SHQQYSSLQ----SSPIPIASPPQMSTSPPAQI--------PPLPLQSMQSLQV 538
+ ++SLQ S + PP+ PPA + P P+ + + Q
Sbjct: 885 LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA 944
Query: 539 Q--PEILSQGQVLVQNALVSEEELPAAEALVQL----PFQTLPPPQTVAVNLQVQPPAPV 592
P LS NA + PA + L L P PPP + Q P +P
Sbjct: 945 HKHPPHLSGPSPFSMNANLPPP--PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 1002
Query: 593 DPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVEL 652
PP + Q +++ PPP + P + + ++HP +
Sbjct: 1003 QPPGLTQSQNL-----------------PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045
Query: 653 PAVASVSASVIKSPSDPSHVSVPP 676
P S P+ P + PP
Sbjct: 1046 PITPPTCPSTSTPPAGPGTSAQPP 1069
Score = 62.4 bits (150), Expect = 2e-09
Identities = 109/436 (25%), Positives = 150/436 (34%), Gaps = 86/436 (19%)
Query: 212 SSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPP-----KSTSQTQSLTICHNKTTVTS 266
S S SS Q Q Q L++ GV + + PP + T S T + + T+
Sbjct: 723 SDSDSSAQQQMLQAQPPALQAPT-GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA 781
Query: 267 SKISQRDPSPES----NKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQP-------H 315
S+ + +P + ++P+L + R S H P+ + P+QP
Sbjct: 782 SQAPNQPQAPTAPVPHTHIQQAPALHPQ-----RPPSPHPPPHPSPHPPLQPLTGSAGQP 836
Query: 316 SLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPA 375
S H Q PLH H S Q P QH P Q GLPP
Sbjct: 837 SAPSHAQPPLHGQGPPGPH-------------------SLQAGPLLQHPGPPQPFGLPPQ 877
Query: 376 PSNAQSQ-HCSPIQSHPS-----PLTVSPNQSQSAQQSVVVSP---------PPPHSP-- 418
S Q+ SP ++P P + S QSQ + + P PPP +P
Sbjct: 878 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 937
Query: 419 -SQSPTIIIHPQALIQPHPLVSSA-LQPGPNLQQSTANQVQATAQLN------LPSHLPL 470
+P HP L P P +A L P P L+ ++ + +P PL
Sbjct: 938 QLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPL 997
Query: 471 PASPVVHIGPVQQSALVSP---------GQQIVSPSHQQYSSLQSSPIPIASPPQMSTSP 521
P+SP G Q L P Q P Q+ + P PI P STS
Sbjct: 998 PSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTST 1057
Query: 522 PAQIPPLPLQSMQSLQVQP--EILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQT 579
P P Q S I + + EE L AE P PPP++
Sbjct: 1058 PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE----PESPPPPPRS 1113
Query: 580 VAVNLQVQPPAPVDPP 595
+ P VD P
Sbjct: 1114 PS-----PEPTVVDTP 1124
Score = 54.3 bits (129), Expect = 6e-07
Identities = 94/444 (21%), Positives = 148/444 (33%), Gaps = 37/444 (8%)
Query: 284 SPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQ 343
SPS S S+ ++ ++ + P K Q+ + S + ++
Sbjct: 613 SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADR----TSSKK 668
Query: 344 QQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQS 403
+ Q I+ NS + N P + + S S PSP + S
Sbjct: 669 TKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728
Query: 404 AQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLN 463
AQQ ++ + PP Q+PT + P P P PGP + +
Sbjct: 729 AQQQMLQAQPP---ALQAPTGVT-PAPSSAP-PGTPQLPTPGPTPSATAVPPQGSPTASQ 783
Query: 464 LPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPA 523
P+ P +PV H +QQ+ + P Q+ S P P PP + A
Sbjct: 784 APNQPQAPTAPVPHT-HIQQAPALHP---------QRPPSPHPPPHPSPHPPLQPLTGSA 833
Query: 524 QIPPLPLQSMQSLQVQ----PEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQT 579
P P + L Q P L G +L LP + Q P T P
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 893
Query: 580 VAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLS----PAAITVG 635
+LQ+ P + + E+ +P + M PPPT PA
Sbjct: 894 PHTSLQL----PASQSALQSQQPPREQPLPPAP---LAMPHIKPPPTTPIPQLPAPQAHK 946
Query: 636 RGEDLTSEHPLLEQVELPAVASVS-ASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMH 694
L+ P LP ++ S + + PS + PPP L+P + +S +
Sbjct: 947 HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS--AHPPPLQLMPQSQPLPSSPAQP 1004
Query: 695 SSIPSIENKPPQAIVKPQILTHVI 718
+ +N PP P H +
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQV 1028
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 79.7 bits (195), Expect = 1e-14
Identities = 121/504 (24%), Positives = 175/504 (34%), Gaps = 83/504 (16%)
Query: 208 PVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSS 267
P +S+SS+ ++ + ++ + L S++ K S T+ +K T T
Sbjct: 614 PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKT-- 671
Query: 268 KISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAP-ASYSPIQPHSLIKHQQIPLH 326
Q P S +GE S +SRS +S + S SP P
Sbjct: 672 ---QEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIP------------ 716
Query: 327 SPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSP 386
SP S QQQ Q QP LQ T P P G P P+ + +
Sbjct: 717 SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP----GTPQLPTPGPTPSATA 772
Query: 387 IQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGP 446
+ P SP SQ+ Q + P PH+ Q + HPQ PHP + P P
Sbjct: 773 V-----PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL-HPQRPPSPHPPPHPS--PHP 824
Query: 447 NLQQST--ANQVQATAQLNLPSHLPLPASP--------VVHIGPVQQSALVSPGQQIVSP 496
LQ T A Q A + P H P P + H GP Q L Q +P
Sbjct: 825 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP 884
Query: 497 ------SHQQYSSLQ----SSPIPIASPPQMSTSPPAQI--------PPLPLQSMQSLQV 538
+ ++SLQ S + PP+ PPA + P P+ + + Q
Sbjct: 885 LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA 944
Query: 539 Q--PEILSQGQVLVQNALVSEEELPAAEALVQL----PFQTLPPPQTVAVNLQVQPPAPV 592
P LS NA + PA + L L P PPP + Q P +P
Sbjct: 945 HKHPPHLSGPSPFSMNANLPPP--PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPA 1002
Query: 593 DPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVEL 652
PP + Q +++ PPP + P + + ++HP +
Sbjct: 1003 QPPGLTQSQNL-----------------PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPP 1045
Query: 653 PAVASVSASVIKSPSDPSHVSVPP 676
P S P+ P + PP
Sbjct: 1046 PITPPTCPSTSTPPAGPGTSAQPP 1069
Score = 62.4 bits (150), Expect = 2e-09
Identities = 109/436 (25%), Positives = 150/436 (34%), Gaps = 86/436 (19%)
Query: 212 SSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPP-----KSTSQTQSLTICHNKTTVTS 266
S S SS Q Q Q L++ GV + + PP + T S T + + T+
Sbjct: 723 SDSDSSAQQQMLQAQPPALQAPT-GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA 781
Query: 267 SKISQRDPSPES----NKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQP-------H 315
S+ + +P + ++P+L + R S H P+ + P+QP
Sbjct: 782 SQAPNQPQAPTAPVPHTHIQQAPALHPQ-----RPPSPHPPPHPSPHPPLQPLTGSAGQP 836
Query: 316 SLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPA 375
S H Q PLH H S Q P QH P Q GLPP
Sbjct: 837 SAPSHAQPPLHGQGPPGPH-------------------SLQAGPLLQHPGPPQPFGLPPQ 877
Query: 376 PSNAQSQ-HCSPIQSHPS-----PLTVSPNQSQSAQQSVVVSP---------PPPHSP-- 418
S Q+ SP ++P P + S QSQ + + P PPP +P
Sbjct: 878 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 937
Query: 419 -SQSPTIIIHPQALIQPHPLVSSA-LQPGPNLQQSTANQVQATAQLN------LPSHLPL 470
+P HP L P P +A L P P L+ ++ + +P PL
Sbjct: 938 QLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPL 997
Query: 471 PASPVVHIGPVQQSALVSP---------GQQIVSPSHQQYSSLQSSPIPIASPPQMSTSP 521
P+SP G Q L P Q P Q+ + P PI P STS
Sbjct: 998 PSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTST 1057
Query: 522 PAQIPPLPLQSMQSLQVQP--EILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQT 579
P P Q S I + + EE L AE P PPP++
Sbjct: 1058 PPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE----PESPPPPPRS 1113
Query: 580 VAVNLQVQPPAPVDPP 595
+ P VD P
Sbjct: 1114 PS-----PEPTVVDTP 1124
Score = 54.3 bits (129), Expect = 6e-07
Identities = 94/444 (21%), Positives = 148/444 (33%), Gaps = 37/444 (8%)
Query: 284 SPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQ 343
SPS S S+ ++ ++ + P K Q+ + S + ++
Sbjct: 613 SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADR----TSSKK 668
Query: 344 QQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQS 403
+ Q I+ NS + N P + + S S PSP + S
Sbjct: 669 TKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728
Query: 404 AQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLN 463
AQQ ++ + PP Q+PT + P P P PGP + +
Sbjct: 729 AQQQMLQAQPP---ALQAPTGVT-PAPSSAP-PGTPQLPTPGPTPSATAVPPQGSPTASQ 783
Query: 464 LPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPA 523
P+ P +PV H +QQ+ + P Q+ S P P PP + A
Sbjct: 784 APNQPQAPTAPVPHT-HIQQAPALHP---------QRPPSPHPPPHPSPHPPLQPLTGSA 833
Query: 524 QIPPLPLQSMQSLQVQ----PEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQT 579
P P + L Q P L G +L LP + Q P T P
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 893
Query: 580 VAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLS----PAAITVG 635
+LQ+ P + + E+ +P + M PPPT PA
Sbjct: 894 PHTSLQL----PASQSALQSQQPPREQPLPPAP---LAMPHIKPPPTTPIPQLPAPQAHK 946
Query: 636 RGEDLTSEHPLLEQVELPAVASVS-ASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMH 694
L+ P LP ++ S + + PS + PPP L+P + +S +
Sbjct: 947 HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS--AHPPPLQLMPQSQPLPSSPAQP 1004
Query: 695 SSIPSIENKPPQAIVKPQILTHVI 718
+ +N PP P H +
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQV 1028
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 79.0 bits (193), Expect = 2e-14
Identities = 109/405 (26%), Positives = 158/405 (39%), Gaps = 90/405 (22%)
Query: 294 VTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQL-------ILQQQQQQI 346
+ + + + Q++AP P+QP +P H PP Q+ LQ Q +
Sbjct: 734 LAQPTPLPQVLAPQPVVPLQP--------VPPHLPPYLAPASQVGAPAQLKPLQMPQAPL 785
Query: 347 QPITLQNSTQDPPPSQHCI-PLQN-HGLPPAPSNAQSQHCSPIQ--SHPSPLTVSPNQSQ 402
QP+ P P I PL GLPPA + + P+ + SP + P+
Sbjct: 786 QPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPS--- 842
Query: 403 SAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQL 462
+ +P PP SP+ + QA+ PHP PG A L
Sbjct: 843 ------LAAPLPPASPA------LPLQAVKLPHP-------PG--------------APL 869
Query: 463 NLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPP 522
+P +P +P + A+ PG +S H + L P+ A+ PQM+ P
Sbjct: 870 AMPCRTIVPNAPAT----IPLLAVAPPGVAALS-IHSAVAQLPGQPVYPAAFPQMA---P 921
Query: 523 AQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAV 582
+PP P ++Q+++ P Q AL + LP LP Q PPQ V
Sbjct: 922 TDVPPSPHHTVQNMRATPP---------QPALPPQPTLPPQPV---LPPQPTLPPQPVLP 969
Query: 583 NLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPP--PPTLSPAAITVGRGEDL 640
+PP PV PP Q + +P + VR + P P +PAA G +
Sbjct: 970 PQPTRPPQPVLPP---QPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATP---GSQI 1023
Query: 641 TSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPP-PPLLLPAA 684
HP P V+A V P P+ V PP P +LLPAA
Sbjct: 1024 LLGHP------APYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAA 1062
Score = 70.1 bits (170), Expect = 1e-11
Identities = 109/402 (27%), Positives = 155/402 (38%), Gaps = 60/402 (14%)
Query: 345 QIQPITLQNSTQDPPPSQHCIPLQNHGLPPA-PSNAQSQHCSPIQSHPSPLTVSPNQSQS 403
Q+Q + Q PP H LPP P++A S TV + SQS
Sbjct: 572 QVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVY-SDSQS 630
Query: 404 AQQSV---------------VVSPPP---PHSPSQSPTIIIHPQALIQPHPLVSSALQPG 445
+QQSV V SPP P P P++ + Q P V S P
Sbjct: 631 SQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPA 690
Query: 446 --PNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQS---ALVSPGQQIVSPSHQQ 500
P+LQQ + + A + P P+P P P QQ A +P Q+++P Q
Sbjct: 691 CPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAP--QP 748
Query: 501 YSSLQSSPIPIASPPQMSTSP----PAQIPPL--PLQSMQSL-QVQPEILSQGQVLVQNA 553
LQ P+P PP ++ + PAQ+ PL P +Q L QV P++ V
Sbjct: 749 VVPLQ--PVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITP 806
Query: 554 LVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVY-QVEDVCEEEMPEES 612
L + LP A L LP T+PP V PP P V+ + P
Sbjct: 807 LAGIDGLPPA--LPDLPTATVPP---------VPPPQYFSPAVILPSLAAPLPPASPALP 855
Query: 613 DECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVS--ASVIKSPSDPS 670
+ V++ P P P V + + PLL V P VA++S ++V + P P
Sbjct: 856 LQAVKLPHPPGAPLAMPCRTIV---PNAPATIPLLA-VAPPGVAALSIHSAVAQLPGQPV 911
Query: 671 HVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQ 712
+ P P S H ++ ++ PPQ + PQ
Sbjct: 912 Y------PAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQ 947
Score = 44.7 bits (104), Expect = 4e-04
Identities = 68/309 (22%), Positives = 106/309 (34%), Gaps = 63/309 (20%)
Query: 359 PPSQHCIPLQNHGLPPAPSNA----QSQHCSPI------QSHPSPLTVSPNQSQSAQQSV 408
P ++H P PP P ++ SQ +P + PS L SQ+ +
Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP 1376
Query: 409 VVSPPPPHSPSQSPTIII-----HPQALIQPHPLVSSALQP-GPNLQQSTANQVQATAQL 462
+PP P +PS P + P P P +A Q GP Q ++++ + L
Sbjct: 1377 PGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPL 1436
Query: 463 NLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASP---PQMST 519
PL P+V +G ++P + + +S P+P +P P T
Sbjct: 1437 AETHEAPLAVQPLV-VG-------LAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGT 1488
Query: 520 SPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQT 579
PA P PL LPAA V L LP P
Sbjct: 1489 PQPALGQPAPL-----------------------------LPAAVGAVSLATSQLPSP-P 1518
Query: 580 VAVNLQVQPPAPVD-----PPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITV 634
+ + QPP+ ++ PP D + + E+ + + P + + V
Sbjct: 1519 LGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEV 1578
Query: 635 GRGEDLTSE 643
G D T E
Sbjct: 1579 G-DRDFTLE 1586
Score = 34.3 bits (77), Expect = 0.60
Identities = 74/320 (23%), Positives = 101/320 (31%), Gaps = 80/320 (25%)
Query: 367 LQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSP----PPPHSPSQSP 422
L GL + QSQ +P+ N + ++ ++ P P P +P SP
Sbjct: 1280 LSTCGLGTGEESRQSQANAPVYQQ--------NVLHTGKRWFIICPVAEHPAPEAPESSP 1331
Query: 423 TIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQ 482
PL S+L P Q +A + PS L
Sbjct: 1332 -------------PLPLSSLPP--EASQDSAPYKDQLSSKEQPSFL------------AS 1364
Query: 483 QSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEI 542
Q L G +P + L S P+ + PQ +P P P S P
Sbjct: 1365 QQLLSQAGPS--NPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGT 1422
Query: 543 LSQG---QVLVQNALVSEEELP-AAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVY 598
QG ++ L E P A + LV P P+ + P P+ PP
Sbjct: 1423 -PQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA-- 1479
Query: 599 QVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASV 658
PE S TP P PA PLL AV +V
Sbjct: 1480 ----------PEPSPH----SGTPQPALGQPA--------------PLLPA----AVGAV 1507
Query: 659 SASVIKSPSDPSHVSVPPPP 678
S + + PS P +VPP P
Sbjct: 1508 SLATSQLPSPPLGPTVPPQP 1527
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 76.6 bits (187), Expect = 1e-13
Identities = 153/707 (21%), Positives = 243/707 (34%), Gaps = 118/707 (16%)
Query: 6 FKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQA 65
F HS + P T ++ T+ TTTT T S + P
Sbjct: 1573 FTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLP------------------- 1613
Query: 66 LHRPPSSAAQYLQQMYAA-QQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSP 124
H PP S + + H + T+A + S ++ ++G T+P
Sbjct: 1614 THVPPFSTSLVTPSTHTVITPTHAQMATSA----SIHSMPTGTIPPPTTLKATGSTHTAP 1669
Query: 125 TGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQ 184
T ++T S SQ +L+T+ T L S + ++ + T T + + +PT T
Sbjct: 1670 TMTLT-TSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNI--TPNPTSTG---- 1722
Query: 185 MYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNG 244
TP T V +S +S S S +T + +L S +SS +
Sbjct: 1723 ----------TPPMT---------VTTSGTSQSRSSFSTAKTSTSLHSH-----TSSTHH 1758
Query: 245 PPKSTSQTQSLTICHNKTTV------TSSKISQRDPSPESNKKGESPSLESRSTA-VTRT 297
P +++ T S+T H T T+S S R P+P + + + ST VT T
Sbjct: 1759 PEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTAT 1818
Query: 298 SSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKV-----SHHQLILQQQQQQIQPITLQ 352
S P +P PH+ +P H P S H +I+ Q ++
Sbjct: 1819 SFQTTTTYP---TPSHPHT-----TLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIH 1870
Query: 353 NSTQD--PPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVV 410
+ PPP+ H PP SP + + S S+ V
Sbjct: 1871 SMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEV 1930
Query: 411 SP------PPPHSPSQSPTIIIHPQALIQ---PHPLVSSALQPGPNLQQS----TANQVQ 457
+P P H+ + + T + H + P P + + G + S TA Q
Sbjct: 1931 TPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQ 1990
Query: 458 ATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQY---SSLQSSPIPIASP 514
T PSH P P H+ P S + ++ +H Q +S+ S+P P
Sbjct: 1991 TTTTYPTPSH-PQTTLP-THVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPP 2048
Query: 515 PQ--MSTSPPAQIPPLPL---------QSMQSLQVQPEILSQGQVLVQNALVSEEELPAA 563
P +T PP+ + S + +S L QN+ P
Sbjct: 2049 PTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPIT 2108
Query: 564 EALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPP 623
L L T P T ++ P+P P V P+ S V +
Sbjct: 2109 TQLPHLSSATTPVSTTNQLSSSFS-PSPSAPSTVSSYVP-SSHSSPQTSSPSVGTSSSFV 2166
Query: 624 PPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPS 670
+ ++ G L++ P ASVSAS + PS P+
Sbjct: 2167 SAPVHSTTLSSGSHSSLSTH---------PTTASVSASPL-FPSSPA 2203
Score = 64.3 bits (155), Expect = 5e-10
Identities = 127/591 (21%), Positives = 217/591 (36%), Gaps = 96/591 (16%)
Query: 9 HSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISV---------YSGSDRHAV 59
HS T P P T + +T + T T+TTS + ++ ++ S HA
Sbjct: 1646 HSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAE 1705
Query: 60 QVIQQALHRPP-------------SSAAQYLQQMYAAQQQHLMLH--------------- 91
+ P +S + ++ + LH
Sbjct: 1706 ATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTS 1765
Query: 92 TAALQQQHLSSSQLQSLAAVQASLSSGRPS-----TSPTGSVTQQSSMSQTSINLSTS-- 144
T ++ H S+ +A ++ SS P+ + PTG+ S+ T+ + T+
Sbjct: 1766 TTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTT 1825
Query: 145 -PTPA--QLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVA 201
PTP+ + S ++ +T T + + T A+ A ++ I P TT+
Sbjct: 1826 YPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTI-PPPTTIK 1884
Query: 202 AVQS--DIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICH 259
A S P ++ ++S + QS ++ T S L +SS + P + + T ++T H
Sbjct: 1885 ATGSTHTAPPMTPTTSGTSQSPSSFSTAKT--STSLPYHTSSTHHPEVTPTSTTNITPKH 1942
Query: 260 NKTTV------TSSKISQRDPSP---ESNKKGESPSLESRSTAVTRTSSIHQLIAPASYS 310
T T+S S R P+P S G SP S + +T TS P +
Sbjct: 1943 TSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPF--SSTGPMTATSFQTTTTYP---T 1997
Query: 311 PIQPHSLIKHQQIPLHSPPSKV-----SHHQLILQQQQQQIQPITLQNSTQD--PPPSQH 363
P P + +P H PP S H +I+ Q ++ ++ PPP+
Sbjct: 1998 PSHPQT-----TLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTL 2052
Query: 364 CIPLQNHGLPP---APSNAQSQHCSPIQSHPSPLTVS-----PNQSQSAQQSVVVSPPPP 415
H PP S H S + S +S P S S S ++ P
Sbjct: 2053 KATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLP 2112
Query: 416 HSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPV 475
H S + + Q +SS+ P P+ + ++ V ++ S + S
Sbjct: 2113 HLSSATTPVSTTNQ--------LSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSS 2164
Query: 476 VHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIP 526
PV + L S +S +H +S+ +SP+ S P ST+ A +P
Sbjct: 2165 FVSAPVHSTTLSSGSHSSLS-THPTTASVSASPL-FPSSPAASTTIRATLP 2213
Score = 64.3 bits (155), Expect = 5e-10
Identities = 128/569 (22%), Positives = 200/569 (35%), Gaps = 66/569 (11%)
Query: 6 FKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQP-QISVYSGS---------- 54
F HS T P T V+ T+ TTTT T S P + +S S
Sbjct: 1797 FTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVI 1856
Query: 55 -DRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQA 113
H ++H P+ + A H S S A
Sbjct: 1857 IPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTST 1916
Query: 114 SL-----SSGRPSTSPTGSV----------TQQSSMSQTSINLSTSPTPAQLISRSQASS 158
SL S+ P +PT + T+ TS + S PTP S SS
Sbjct: 1917 SLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSS 1976
Query: 159 --STSGSITQQTMLLGSTSPTLTASQAQMYLRA---QMLIFTPATTVAAVQSDIPVVSSS 213
S++G +T + +T PT + Q + + TP+T + + + +S+
Sbjct: 1977 PFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSA 2036
Query: 214 SSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPK--STSQTQSLTICHNKTTVTSSKISQ 271
S S + T TL++ S+ PP +TS T + T +SS IS
Sbjct: 2037 SIHSTPT-GTVPPPTTLKA-----TGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISS 2090
Query: 272 RD--PSPESNKKGESP---SLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLH 326
P S++ SP L S+A T S+ +QL + S SP P ++ +
Sbjct: 2091 SSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHS 2150
Query: 327 SPPSKVSHHQLILQQQQQQIQPITLQN------STQDPPPSQHCIPLQNHGLPPAPSNAQ 380
SP + + TL + ST S PL P +P+ +
Sbjct: 2151 SPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPL----FPSSPAAST 2206
Query: 381 SQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSP-PPPHSPSQSPTIIIHPQALIQPHPLVS 439
+ + + SP T+S S +V VSP P H S + P+ H +
Sbjct: 2207 TIRATLPHTISSPFTLSALLPIS---TVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPA 2263
Query: 440 SALQPGPNLQQSTANQVQATAQLNLPSHLP-LPASPVVHIGPVQQSALVSPGQQIVSPSH 498
+ Q + S +V + ++L S + +P SPV ++ +SP + ++
Sbjct: 2264 FSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLT--- 2320
Query: 499 QQYSSLQSSPIPIASPPQMSTSPPAQIPP 527
SSL + AS P S P P
Sbjct: 2321 ---SSLTAHGSTPASAPVSSLGTPTPTSP 2346
Score = 61.2 bits (147), Expect = 5e-09
Identities = 99/454 (21%), Positives = 166/454 (36%), Gaps = 70/454 (15%)
Query: 91 HT-AALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQ 149
HT A+ Q L + L S +S RP+T+ T T + T + +T PT Q
Sbjct: 1244 HTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQ 1303
Query: 150 LISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPV 209
+R+ A ST+ T S AQ R M + TPAT+ + P
Sbjct: 1304 ATTRATA----------------STASPATTSTAQSTTRTTMTLPTPATSGTS-----PT 1342
Query: 210 VSSSSSSSCQ-SAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSK 268
+ S++ + ATQ ++ Q G P + T+ TT T +
Sbjct: 1343 LPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATE--------TTQTRTT 1394
Query: 269 ISQRDP-SPESNKKGESPSLESRSTAVTRTSSIHQLIAPASY-SPIQPHSLIKHQQIPLH 326
P +P + + ST +S H A +Y +P P + +P H
Sbjct: 1395 TEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH---ATTTYPTPSHPET-----TLPTH 1446
Query: 327 SPPSKVSHHQLILQQQQQQIQPITLQNSTQD----------PPPSQHCIPLQNHGLPP-- 374
PP S L+ I P Q +T PPP+ H PP
Sbjct: 1447 VPPFSTS---LVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPIT 1503
Query: 375 APSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSV------VVSPPPPHSPSQSPTIIIHP 428
++ SQ S ++ +P ++ + S + V ++P P + +++P +
Sbjct: 1504 PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNS 1563
Query: 429 QALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASP----VVHIGPVQQS 484
+P P ++ P + S+ + AT+ + P P+ P H+ P S
Sbjct: 1564 ATSSRPPPPFTTHSPPTGSSPFSSTGPMTATS-FKTTTTYPTPSHPQTTLPTHVPPFSTS 1622
Query: 485 ALVSPGQQIVSPSHQQY---SSLQSSPIPIASPP 515
+ +++P+H Q +S+ S P PP
Sbjct: 1623 LVTPSTHTVITPTHAQMATSASIHSMPTGTIPPP 1656
Score = 53.1 bits (126), Expect = 1e-06
Identities = 95/410 (23%), Positives = 151/410 (36%), Gaps = 35/410 (8%)
Query: 9 HSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSD---RHAVQVIQQA 65
HST T P P T + +T + T+TTS + S + S + + Q +
Sbjct: 2039 HSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNS 2098
Query: 66 LHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPT 125
RPPSS Q HL T + + SS + +++SS PS+
Sbjct: 2099 SSRPPSSP-------ITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSH-- 2149
Query: 126 GSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTAS-QAQ 184
S S+ S+S A + S + +S S S T T S SP +S A
Sbjct: 2150 ----SSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAAS 2205
Query: 185 MYLRAQM--LIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNL--TLRSQKLGVLSS 240
+RA + I +P T A + VS + SS S+ + T S S
Sbjct: 2206 TTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFS 2265
Query: 241 SQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSI 300
SQ+ +STS T + + +S ++ SP +N P T TSS
Sbjct: 2266 SQSTTSRSTSLTTRVPT--SGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSS- 2322
Query: 301 HQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPP 360
L A S P S + P+ S +++QQ++I +
Sbjct: 2323 --LTAHGSTPASAPVSSL--------GTPTPTSPGVCSVREQQEEITFKGCMANVTVTRC 2372
Query: 361 SQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTV-SPNQSQSAQQSVV 409
CI + + +A+ C P+ S+ L + P+ S ++ V+
Sbjct: 2373 EGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVL 2422
Score = 51.2 bits (121), Expect = 5e-06
Identities = 163/761 (21%), Positives = 264/761 (34%), Gaps = 154/761 (20%)
Query: 10 STAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRP 69
ST T P PG + T T +T T T TT + Q P + H P
Sbjct: 1368 STTGPTTPQPGQPTRPTATETTQTRT-TTEYTTPQTPHTT-----------------HSP 1409
Query: 70 PSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPS----TSPT 125
P++ + + S+ + + A+ + PS T PT
Sbjct: 1410 PTAGSP------------------------VPSTGPVTATSFHATTTYPTPSHPETTLPT 1445
Query: 126 GSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQM 185
+S+ S + +PT AQ+ + + S+ +G+I T L +T T TA
Sbjct: 1446 HVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPT-TLKATGSTHTAPP--- 1501
Query: 186 YLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGP 245
TP T+ + + SS S T + + T + V P
Sbjct: 1502 --------ITPTTSGTS--------QAHSSFSTNKTPTSLHSHTSSTHHPEVT------P 1539
Query: 246 PKSTSQTQSLTICHNKTTV--TSSKISQRDPSP---ESNKKGESPSLESRSTAVTRTSSI 300
+T+ T + T +T V T+S S R P P S G SP S + +T TS
Sbjct: 1540 TSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPF--SSTGPMTATSFK 1597
Query: 301 HQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQD--- 357
P +P P + +P H PP S L+ I P Q +T
Sbjct: 1598 TTTTYP---TPSHPQT-----TLPTHVPPFSTS---LVTPSTHTVITPTHAQMATSASIH 1646
Query: 358 -------PPP-------SQHCIP---LQNHGLPPAPSNAQSQHCS-PIQSHPSPLTVSPN 399
PPP S H P L G A S+ + S + SH T S +
Sbjct: 1647 SMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSH----TSSTH 1702
Query: 400 QSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTAN----Q 455
+++ S P P S + +P + + Q S+A + +L T++ +
Sbjct: 1703 HAEATSTSTTNITPNPTS-TGTPPMTVTTSGTSQSRSSFSTA-KTSTSLHSHTSSTHHPE 1760
Query: 456 VQATAQLNL-PSHLPL-PASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIAS 513
V +T+ ++ P+H +PV H S L +P P+ S + P+ S
Sbjct: 1761 VTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS-STGPVTATS 1819
Query: 514 PPQMSTSPPAQIP----PLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQL 569
+T P P P + S + V P S V++ + ++ + ++ +
Sbjct: 1820 FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTP---STHTVIIP----THTQMATSASIHSM 1872
Query: 570 PFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSP 629
P T+PPP T+ P+ P + + S + P ++P
Sbjct: 1873 PTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTP 1932
Query: 630 AAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPP----------PPL 679
+ T ++T +H P + SAS + P+ P PP P
Sbjct: 1933 TSTT-----NITPKH-TSTGTRTPVAHTTSASSSRLPT-PFTTHSPPTGSSPFSSTGPMT 1985
Query: 680 LLPAATTRSNSTSMHSSIPSIENKPP--QAIVKPQILTHVI 718
TT + T H + PP ++V P T +I
Sbjct: 1986 ATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVII 2026
Score = 40.8 bits (94), Expect = 0.006
Identities = 97/483 (20%), Positives = 155/483 (32%), Gaps = 91/483 (18%)
Query: 262 TTVTSSKISQRDPSPESNKKGESPS----LESRSTAVTRTSSIHQ------LIAPASYSP 311
T+ T +S PSP SN SP+ L + T+ T+S + + P + S
Sbjct: 1226 TSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSG 1285
Query: 312 IQPHSLIKH------------QQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPP 359
+ P + ++ + + P+ S Q + P T S P
Sbjct: 1286 LPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPK 1345
Query: 360 PSQHCIP----LQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPP 415
+ +P Q G P P++ +P P+ T + +Q+ + +P P
Sbjct: 1346 STNQELPGTTATQTTGPRPTPASTTGP-TTPQPGQPTRPTAT-ETTQTRTTTEYTTPQTP 1403
Query: 416 HSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPV 475
H+ PT A P P+ TA AT PSH P P
Sbjct: 1404 HTTHSPPT-----------------AGSPVPSTGPVTATSFHATTTYPTPSH-PETTLP- 1444
Query: 476 VHIGPVQQSALVSPGQQIVSPSHQQY---SSLQSSPIPIASPP-------QMSTSPP--- 522
H+ P S + +++P+H Q +S S+P PP T+PP
Sbjct: 1445 THVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITP 1504
Query: 523 -------------AQIPPLPLQSMQSLQVQPEIL-SQGQVLVQNALVSEEELPAAEALVQ 568
P L S S PE+ + + N + P A
Sbjct: 1505 TTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSA 1564
Query: 569 LPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLS 628
+ PP T + P + P + P + T PP S
Sbjct: 1565 TSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTL---PTHVPP-FS 1620
Query: 629 PAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRS 688
+ +T +T H A + SAS+ P+ ++PPP L +T +
Sbjct: 1621 TSLVTPSTHTVITPTH---------AQMATSASIHSMPTG----TIPPPTTLKATGSTHT 1667
Query: 689 NST 691
T
Sbjct: 1668 APT 1670
>gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo
sapiens]
Length = 1083
Score = 75.1 bits (183), Expect = 3e-13
Identities = 150/703 (21%), Positives = 256/703 (36%), Gaps = 113/703 (16%)
Query: 110 AVQASLSSGR---PSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQ 166
AV A++S+ R P + T + S++S+ ++++ P+ A I R S + IT
Sbjct: 288 AVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITL 347
Query: 167 QTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQ-SDIPVVSSSSSSSCQSAATQV 225
+ P L + Q++ AQ IF+ T VAA + I ++ S++ + +
Sbjct: 348 PS------HPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHT 401
Query: 226 QNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESP 285
Q T + V S S + +TS + + T TS +I P+ S+ S
Sbjct: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISG 461
Query: 286 SLESRSTAVTRTSSIHQLIAPASYS------PIQPHSLIKHQQIPLHSPPSKVSHHQLIL 339
S + T S ++ P + P + L H P+ S S + + +
Sbjct: 462 HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSA 521
Query: 340 QQQQQQIQPIT------------LQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPI 387
Q I T +Q T D ++H G+ PAP + Q +PI
Sbjct: 522 QAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHI-----QGIQPAPISTQGIQPAPI 576
Query: 388 QS---HPSPLTVSPNQSQSAQQSVVVSPPP-----PHSPSQSPTIIIHPQALIQPHPLVS 439
+ P+PL S + + + P P P ++ +++ A I +P +S
Sbjct: 577 GTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANP-IS 635
Query: 440 SALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQ 499
+ P Q +A N P+ P ++ P V + ++ P
Sbjct: 636 NPFSAAPAATTVVQTHSQ-SASTNAPAQGSSPRPSILRKKPATDGMAVR--KTLIPPQPP 692
Query: 500 QYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEE 559
+S + + S + ++ P P + P +S V QN +++
Sbjct: 693 DVASPR-----VESSMRSTSGSPRPAGAKPKSEIHVSMATPVTVSMETVSNQN---NDQP 744
Query: 560 LPAAEALVQLPFQTLP-------PPQTVAVNLQVQPPA-PVDPPVVYQVEDVCEEEMPEE 611
A Q P T+P PP AV L P A P+ PP+
Sbjct: 745 TIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPI--------------- 789
Query: 612 SDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSH 671
+ PPP ++TVG L V P V + P D
Sbjct: 790 ----TTIAAAPPP------SVTVGGS---------LSSVLGPPVPEIKVKEEVEPMDIMR 830
Query: 672 VSVPPPPL----LLPAATTRSNSTSMHSSIPSIENKPPQAI--VKPQILTHVI---EGFV 722
PPL + P+ +N+ SM +S + PP A KP+ HVI EG +
Sbjct: 831 PVSAVPPLATNTVSPSLALLANNLSMPTS-----DLPPGASPRKKPRKQQHVISTEEGDM 885
Query: 723 IQ-EGLEPFPVSRSSLLIEQPVKKRP---LLDNQVINSVCVQP 761
++ + + SLL++ +K P +D + + V V+P
Sbjct: 886 METNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRP 928
Score = 38.5 bits (88), Expect = 0.032
Identities = 95/490 (19%), Positives = 180/490 (36%), Gaps = 101/490 (20%)
Query: 285 PSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLI-----L 339
P L + ST +++ S Q+ S I P + + + S+VS + + L
Sbjct: 33 PRLGAPSTGLSQAPS--QIANSGSAGLINPAATVNDES----GRDSEVSAREHMSSSSSL 86
Query: 340 QQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPN 399
Q ++++ +P+ ++ Q S H H + A +P+ P ++P
Sbjct: 87 QSREEKQEPVVVRPYPQVQMLSTH------HAVASA---------TPVAVTAPPAHLTPA 131
Query: 400 QSQSAQQSVVVSPPPPHSPSQ------------------SPTIIIH---PQALIQPHPLV 438
S + ++ PP P PS+ T+ + PQA P +
Sbjct: 132 VPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATI 191
Query: 439 SSALQPGPNLQQ-STANQVQATAQLNLP--------SHLPLPASPVVHIGPVQQSALVSP 489
S NL T N + + N P SHLP A+ + + + ++ P
Sbjct: 192 SGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP 251
Query: 490 GQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVL 549
Q+ + + Q + PI S P ++TS IPP + ++ + +
Sbjct: 252 TSQLPNAATAQPAVQHIIHQPIQSRPPVTTS--NAIPPAVVATVSATR------------ 297
Query: 550 VQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMP 609
Q+ +++ A ++ + P ++ P + A++ +Q PA Q DV
Sbjct: 298 AQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS--IQRPA--------QSRDVTTR--- 344
Query: 610 EESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDP 669
+ + P T T+ + ++ P+ P +A+ + +
Sbjct: 345 ------ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398
Query: 670 SHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEP 729
SH P ++ T S S H++ + N P +V PQ +TH ++P
Sbjct: 399 SHTQAPTSTIV----TMTVPSHSSHATAVTTSNIPVAKVV-PQQITHT------SPRIQP 447
Query: 730 -FPVSRSSLL 738
+P RSSL+
Sbjct: 448 DYPAERSSLI 457
>gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo
sapiens]
Length = 1048
Score = 74.3 bits (181), Expect = 5e-13
Identities = 150/685 (21%), Positives = 249/685 (36%), Gaps = 112/685 (16%)
Query: 110 AVQASLSSGR---PSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQ 166
AV A++S+ R P + T + S++S+ ++++ P+ A I R S + IT
Sbjct: 288 AVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITL 347
Query: 167 QTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQ-SDIPVVSSSSSSSCQSAATQV 225
+ P L + Q++ AQ IF+ T VAA + I ++ S++ + +
Sbjct: 348 PS------HPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHT 401
Query: 226 QNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESP 285
Q T + V S S + +TS + + T TS +I P+ S+ S
Sbjct: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISG 461
Query: 286 SLESRSTAVTRTSSIHQLIAPASYS------PIQPHSLIKHQQIPLHSPPSKVSHHQLIL 339
S + T S ++ P + P + L H P+ S S + + +
Sbjct: 462 HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSA 521
Query: 340 QQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQS-HPSPLTVSP 398
Q IT Q + H P+Q + H IQ P+P++
Sbjct: 522 QAPN---SAITAQTGV-GVASTVHLNPMQ-------LMTVDASHARHIQGIQPAPISTQG 570
Query: 399 NQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQA 458
+ P P +P P + Q + P+ + LQP P Q + +
Sbjct: 571 -----------IQPAPIGTPGIQPA-PLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKT 618
Query: 459 TAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASP-PQM 517
+A + L + P+ +P V +H Q S+ ++P +SP P +
Sbjct: 619 SA-------VVLADGATIVANPISNPFSAAPAATTVVQTHSQ-SASTNAPAQGSSPRPSI 670
Query: 518 STSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLP-- 575
PA P + P +S V QN +++ A Q P T+P
Sbjct: 671 LRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQN---NDQPTIAVPPTAQQPPPTIPTM 727
Query: 576 -----PPQTVAVNLQVQPPA-PVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSP 629
PP AV L P A P+ PP+ + PPP
Sbjct: 728 IAAASPPSQPAVALSTIPGAVPITPPI-------------------TTIAAAPPP----- 763
Query: 630 AAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPL----LLPAAT 685
++TVG L V P V + P D PPL + P+
Sbjct: 764 -SVTVGGS---------LSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLA 813
Query: 686 TRSNSTSMHSSIPSIENKPPQAI--VKPQILTHVI---EGFVIQ-EGLEPFPVSRSSLLI 739
+N+ SM +S + PP A KP+ HVI EG +++ + + SLL+
Sbjct: 814 LLANNLSMPTS-----DLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLV 868
Query: 740 EQPVKKRP---LLDNQVINSVCVQP 761
+ +K P +D + + V V+P
Sbjct: 869 KAEKRKSPPKEYIDEEGVRYVPVRP 893
Score = 38.5 bits (88), Expect = 0.032
Identities = 95/490 (19%), Positives = 180/490 (36%), Gaps = 101/490 (20%)
Query: 285 PSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLI-----L 339
P L + ST +++ S Q+ S I P + + + S+VS + + L
Sbjct: 33 PRLGAPSTGLSQAPS--QIANSGSAGLINPAATVNDES----GRDSEVSAREHMSSSSSL 86
Query: 340 QQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPN 399
Q ++++ +P+ ++ Q S H H + A +P+ P ++P
Sbjct: 87 QSREEKQEPVVVRPYPQVQMLSTH------HAVASA---------TPVAVTAPPAHLTPA 131
Query: 400 QSQSAQQSVVVSPPPPHSPSQ------------------SPTIIIH---PQALIQPHPLV 438
S + ++ PP P PS+ T+ + PQA P +
Sbjct: 132 VPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATI 191
Query: 439 SSALQPGPNLQQ-STANQVQATAQLNLP--------SHLPLPASPVVHIGPVQQSALVSP 489
S NL T N + + N P SHLP A+ + + + ++ P
Sbjct: 192 SGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP 251
Query: 490 GQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVL 549
Q+ + + Q + PI S P ++TS IPP + ++ + +
Sbjct: 252 TSQLPNAATAQPAVQHIIHQPIQSRPPVTTS--NAIPPAVVATVSATR------------ 297
Query: 550 VQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMP 609
Q+ +++ A ++ + P ++ P + A++ +Q PA Q DV
Sbjct: 298 AQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS--IQRPA--------QSRDVTTR--- 344
Query: 610 EESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDP 669
+ + P T T+ + ++ P+ P +A+ + +
Sbjct: 345 ------ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398
Query: 670 SHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEP 729
SH P ++ T S S H++ + N P +V PQ +TH ++P
Sbjct: 399 SHTQAPTSTIV----TMTVPSHSSHATAVTTSNIPVAKVV-PQQITHT------SPRIQP 447
Query: 730 -FPVSRSSLL 738
+P RSSL+
Sbjct: 448 DYPAERSSLI 457
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 73.9 bits (180), Expect = 7e-13
Identities = 137/606 (22%), Positives = 219/606 (36%), Gaps = 72/606 (11%)
Query: 120 PSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTS-GSITQQTMLLGSTSPTL 178
P ++P T+ + S S N ++ P + R+ + +TS G ++ G+T P
Sbjct: 71 PESAPRAGPTRSAGTS--SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG- 127
Query: 179 TASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVL 238
Q + + A+ + T A +S + + +S + T + RS+ G
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG-PTPGTPSPAMARRSRAAGTE 186
Query: 239 SSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTS 298
P +++ + T K+ ++S+ S +PSP + ++ + R + + +S
Sbjct: 187 VGLPR--PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 299 SIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDP 358
S L +PA P P +H + Q ++P + +D
Sbjct: 245 SATPLSSPARSGP------------SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
Query: 359 PPSQHCIPLQNHGLP-PAPSNA---QSQHCSPIQSHPS--------PLTVSPNQSQSAQQ 406
P+ PL + L P+PS A Q+ P H S PL ++P S SA
Sbjct: 293 APALG--PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP-PSPSAPP 349
Query: 407 SVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPS 466
S+ P PP +P T + L H + P P L QA L LP
Sbjct: 350 SLQTLPSPPATPPSQATTSLGSPTLQATHSFL-----PSPPLSPLATPPPQAPPALALP- 403
Query: 467 HLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPP-QMSTSPPAQI 525
PL A P P S L +P Q +P+ LQ+ P SPP Q SPPA
Sbjct: 404 --PLQAPPSPPASP-PLSPLATPSPQ--APNALAVHLLQAPFSPPPSPPVQAPFSPPAS- 457
Query: 526 PPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQ 585
PP+ + Q P + + + + S P+A Q P PP +A
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517
Query: 586 VQPPAPVDPPVVYQVEDVCE--EEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSE 643
PPA PP+ + P + M PP +P +
Sbjct: 518 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA--------- 568
Query: 644 HPLLEQVELPAVASVSASVIKSPSDPSHVSV-------------PPPPLLLPAATTRSNS 690
PLL+ P + + + P+ SV PPPP P++T
Sbjct: 569 -PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 627
Query: 691 TSMHSS 696
+ HSS
Sbjct: 628 LAGHSS 633
Score = 45.8 bits (107), Expect = 2e-04
Identities = 94/421 (22%), Positives = 138/421 (32%), Gaps = 82/421 (19%)
Query: 109 AAVQASLSSGRPSTSPTGSVT-QQSSMSQTSINLSTSPTPA------------QLISRSQ 155
A + L PS P + S+S S + +T P+PA + SRS
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 156 ASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTV--------------- 200
+SS+T S ++ +P A +Q + + P T
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
Query: 201 --------AAVQSD----IPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGP-PK 247
AA+QS +P SSS +CQ A L L S Q P P
Sbjct: 303 PLATPSPSAALQSQAPPTLPATPHSSSLTCQLATP----LPLAPPSPSAPPSLQTLPSPP 358
Query: 248 STSQTQSLTICHNKTTVTSSKISQRDP-SPESNKKGESPS-------------------- 286
+T +Q+ T + T + P SP + ++P
Sbjct: 359 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 418
Query: 287 -LESRSTAVTRTSSIHQLIAPASYSPIQPHSL-----IKHQQIPLHSPPSKVSHHQLILQ 340
L + S ++H L AP S P P P +PPS+
Sbjct: 419 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 478
Query: 341 QQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLP---PAPSNAQSQHCSPIQSHPSPLTVS 397
Q P + S PP Q PL L P P + P+Q+ PSP
Sbjct: 479 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 538
Query: 398 PNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQ-------PGPNLQQ 450
P Q+ + + + P P Q+P ++ P + P P S LQ PGP+
Sbjct: 539 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 598
Query: 451 S 451
S
Sbjct: 599 S 599
>gi|32699038 sterile alpha motif domain containing 7 [Homo sapiens]
Length = 446
Score = 73.9 bits (180), Expect = 7e-13
Identities = 34/60 (56%), Positives = 43/60 (71%)
Query: 931 WTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARIN 990
WTVDDV +FI SLPGC D A F+ IDG+ L LL E+HL M +KLGPALKI ++++
Sbjct: 327 WTVDDVHSFIRSLPGCSDYAQVFKDHAIDGETLPLLTEEHLRGTMGLKLGPALKIQSQVS 386
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 72.8 bits (177), Expect = 2e-12
Identities = 135/502 (26%), Positives = 185/502 (36%), Gaps = 106/502 (21%)
Query: 264 VTSSKISQRDPSPE--------SNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPH 315
VTS +R P E S KG S S ES S++ + +S S + + P
Sbjct: 671 VTSCLRKKRKPQAEKVDVIAGSSKMKGFSSS-ESESSSESSSSDSED-----SETEMAPK 724
Query: 316 SLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPA 375
S K H + HH QQ QQ P+ Q PPP Q PP
Sbjct: 725 SKKKG-----HPGREQKKHHHHHHQQMQQAPAPVP----QQPPPPPQQ---------PPP 766
Query: 376 PSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPH 435
P Q Q P P P P Q+ A +S PPP +Q P ++ PQ
Sbjct: 767 PPPPQQQQQPP---PPPPPPSMPQQAAPAMKS----SPPPFIATQVP--VLEPQ------ 811
Query: 436 PLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGP--VQQSALVSPGQQI 493
L S P + Q + Q LP HLP P H P + Q A+VSP
Sbjct: 812 -LPGSVFDPIGHFTQPILHLPQP----ELPPHLPQPPE---HSTPPHLNQHAVVSP---- 859
Query: 494 VSPSHQQYSSLQSSPIPIASP-PQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQN 552
H S P A+ P PPA P L + L QP + QVL++
Sbjct: 860 -PALHNALPQQPSRPSNRAAALPPKPARPPAVSPAL---TQTPLLPQPPMAQPPQVLLE- 914
Query: 553 ALVSEEELPA---AEALVQLPFQTL-----PPPQTVAVNLQVQPPAPVDPPVVYQVEDVC 604
+EE PA +QL Q L P P +V +Q QPP P+ PP V+
Sbjct: 915 ----DEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQL 970
Query: 605 EEEMP-----EESDECVRMDRTPPPPT-LSPAAITVGRGEDLTSE-----HPLLEQVELP 653
+++ P + + + PP P L P + + + HP Q P
Sbjct: 971 QQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP 1030
Query: 654 AVASVSASVIK---SP----SDP---SHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENK 703
+ VI+ SP SDP H+ P PL++ + + H S P +
Sbjct: 1031 PQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQ 1090
Query: 704 PPQ------AIVKPQILTHVIE 719
P + ++V+PQ L V E
Sbjct: 1091 PKKQELRAASVVQPQPLVVVKE 1112
Score = 63.9 bits (154), Expect = 7e-10
Identities = 108/397 (27%), Positives = 146/397 (36%), Gaps = 77/397 (19%)
Query: 272 RDPSPESNKKGESPSLESR----STAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHS 327
+ PS SN+ P +R S A+T+T + Q P P P L++ ++ P +
Sbjct: 868 QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQ---PPMAQP--PQVLLEDEEPP--A 920
Query: 328 PPSKVSHHQLILQQQQQQIQPITLQNS----TQDPPPSQHCIPLQNHGLPPAPSNAQSQH 383
PP QL LQQ Q+ P L S +Q PPP LPP P
Sbjct: 921 PPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP-----------LPPPP------- 962
Query: 384 CSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQ 443
HPS QQ + PPPP P P PQ QP P LQ
Sbjct: 963 ------HPS-----------VQQQLQQQPPPPPPPQPQPP----PQQQHQPPPRPVH-LQ 1000
Query: 444 PGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSS 503
P +Q ST Q Q P H P P P Q + Q SP H +
Sbjct: 1001 P---MQFSTHIQQPPPPQGQQPPHPPPGQQPP----PPQPAKPQQVIQHHHSPRHHKSDP 1053
Query: 504 LQSSPIPIASPPQMSTSPP-AQIPPLPLQSMQSLQVQP---EILSQGQVLVQNALVSEEE 559
+ + A P M SP +Q L QS VQP E+ + V Q +V +EE
Sbjct: 1054 YSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEE 1113
Query: 560 LPAAEALVQLPFQTL----PP--PQTVA--VNLQVQP---PAPVDPPVVYQVEDVCEEEM 608
+ + PF PP P+++ V+L +P P V PV+ E
Sbjct: 1114 KIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPG 1173
Query: 609 PEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHP 645
+ D+ + +TP P +G L +HP
Sbjct: 1174 APDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHP 1210
Score = 35.8 bits (81), Expect = 0.21
Identities = 44/179 (24%), Positives = 67/179 (37%), Gaps = 42/179 (23%)
Query: 350 TLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSP--------------LT 395
T+ N+TQ P Q P N PP P+Q+ P P +T
Sbjct: 195 TVPNTTQASTPPQTQTPQPN---PP-----------PVQATPHPFPAVTPDLIVQTPVMT 240
Query: 396 VSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQ 455
V P Q V P PP +P+ P +Q HP + +A ++ +
Sbjct: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQP---------VQSHPPIIAATPQPVKTKKGVKRK 291
Query: 456 VQATAQLNL-PSHLP--LPASP-VVHIGPVQQSAL-VSPGQQIVSPSHQQYSSLQSSPI 509
T + P H P LP P +G ++S+ V P ++ V S Q + +SS +
Sbjct: 292 ADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKV 350
Score = 32.7 bits (73), Expect = 1.7
Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 15/98 (15%)
Query: 564 EALVQLPFQTLPPPQTVAVNLQV-----QPPAPVDPPVVYQVEDVCEEEMPEESDECV-- 616
+ +VQ P T+ PPQ + V PPAP PV + P ++ + V
Sbjct: 231 DLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKR 290
Query: 617 RMDRTPP--------PPTLSPAAITVGRGEDLTSEHPL 646
+ D T P PP+L P T G+ S P+
Sbjct: 291 KADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPV 328
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 71.6 bits (174), Expect = 3e-12
Identities = 136/755 (18%), Positives = 270/755 (35%), Gaps = 71/755 (9%)
Query: 10 STAMDTEPNPGTS---SVSTTTSSTTTTTIT------TSSSRMQQPQISVYSGSDRHAVQ 60
+TA + +P T+ S++T+T S +T +T T + + +S + V
Sbjct: 425 TTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVT 484
Query: 61 VIQQALHRPPSSAAQYLQQMYAAQQQHLM-------LHTAALQQQHLSSSQLQSLAAVQA 113
+A PP++ + ++ + + A+ + LS++ + + V
Sbjct: 485 TSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTT 544
Query: 114 SLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQA----------------- 156
S + ST+P G+ S+ S+ S L+ P +L+ S+A
Sbjct: 545 SSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTS 604
Query: 157 -----SSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVS 211
SS+T+ + T T+T+ L A T +TT V S+ PV +
Sbjct: 605 SEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTT--PVDSNTPVTT 662
Query: 212 SSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQ 271
S+ ++ S++T + ++ + S+ P +T +L +T++++ +
Sbjct: 663 STEAT---SSSTTAEGTSMPTSTYTEGSTPLTSMPVNT----TLVASSEASTLSTTPVDT 715
Query: 272 RDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSK 331
P S + SP+ ++ T T S + P + P+ L + L + P
Sbjct: 716 STPVTTSTEASSSPTTADGASMPTSTPS--EGSTPLTSMPVSKTLLTSSEASTLSTTPLD 773
Query: 332 VSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHP 391
S H I + P T + ++ PL +P + + S S + + P
Sbjct: 774 TSTH--ITTSTEASCSPTTTEGTSMPISTPSEGSPLLT-SIPVSITPVTSPEASTLSTTP 830
Query: 392 ----SPLTVSPNQSQSAQQSVVVS-PPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGP 446
SP+T S S S + S P +S ++P + + +S+
Sbjct: 831 VDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPV 890
Query: 447 NLQQSTANQVQATAQ------LNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQ 500
+ N +A + ++P+ P S + P + +VS + +S +
Sbjct: 891 DTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVD 950
Query: 501 YSSLQSSPIPIASPPQMS--TSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEE 558
S+ ++ S P + TS P P + S V +++ + + +
Sbjct: 951 TSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDS 1010
Query: 559 ELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESD-ECVR 617
P L + PPP ++ P+ P+ E S
Sbjct: 1011 NTP----LTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTP 1066
Query: 618 MDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPP 677
D + P T S A+ + + + + P + ++ + S+ S +S P
Sbjct: 1067 ADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPV 1126
Query: 678 PLLLPAAT-TRSNSTSMHSSIPSIENKPPQAIVKP 711
+P T T ++S+ + SI PP P
Sbjct: 1127 DTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTP 1161
Score = 67.4 bits (163), Expect = 6e-11
Identities = 154/722 (21%), Positives = 279/722 (38%), Gaps = 95/722 (13%)
Query: 8 DHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQIS----VYSGSDRHAVQVIQ 63
D ST + T G+S + +S T+T + S+ + +S V S + H+ +
Sbjct: 2364 DTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVD 2423
Query: 64 QALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTS 123
+ P +++ + A+ + + L+S + + V S +G ST+
Sbjct: 2424 TS--TPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVV--SSEAGTLSTT 2479
Query: 124 PTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQA 183
P + T + TS S+SPT A+ I S+++ GS T T + ST+P +
Sbjct: 2480 PVDTSTPMT----TSTEASSSPTTAEDIV-VPISTASEGS-TLLTSIPVSTTPVASP--- 2530
Query: 184 QMYLRAQMLIFTPATTVAAVQSDIPVVSSS--SSSSCQSAATQVQNLTLRSQKLGVLSSS 241
A L TP V S+ PVV+S+ SSS+ + T + T + S
Sbjct: 2531 ----EASTLSTTP------VDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMP 2580
Query: 242 QNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIH 301
+ P ++S+ +L+ T++ + ++ SP + K P + + S T +SI
Sbjct: 2581 VSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMP-ISTPSEVSTSLTSIL 2639
Query: 302 QLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQ-DPPP 360
P + S S + V L+ P T + S+ P
Sbjct: 2640 VSTMPVASSEASTLS------------TTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTP 2687
Query: 361 SQHCIPLQNHGLPP---APSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSV-----VVSP 412
+ PL N + A S A + +P+ + +P+T S S S + + +P
Sbjct: 2688 GERSTPLTNILVSTTLLANSEASTLSTTPVDT-STPVTTSAEASSSPTTAEGTSMRISTP 2746
Query: 413 PPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQST-ANQVQATAQL-NLPSHLPL 470
+P S + P A + + ++A+ + ST A+ TA++ ++P+ P
Sbjct: 2747 SDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPS 2806
Query: 471 PASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPL 530
S + PV + + S + +L ++P+ ++P ++TS A P
Sbjct: 2807 ETSTPLTSMPVNHTPVAS----------SEAGTLSTTPVDTSTP--VTTSTKASSSP--- 2851
Query: 531 QSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEA--LVQLPFQTLPPPQT--------- 579
+ + + V S+G L+ + VS + ++EA L P T P T
Sbjct: 2852 TTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPT 2911
Query: 580 --VAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTP----PPPTLSPAAI- 632
++ + P+ V P+ + +P E + TP P T S A
Sbjct: 2912 TAEGTSMPISTPSEVSTPLT----SILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASS 2967
Query: 633 --TVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNS 690
T G + P + L ++ SVS + S S+ S +S P P T+ S
Sbjct: 2968 SPTTAEGTSMPISTPGERRTPLTSM-SVSTMPVAS-SEASTLSRTPADTSTPVTTSTEAS 3025
Query: 691 TS 692
+S
Sbjct: 3026 SS 3027
Score = 64.3 bits (155), Expect = 5e-10
Identities = 160/759 (21%), Positives = 275/759 (36%), Gaps = 126/759 (16%)
Query: 1 MAEAEFKDHSTAMDTEP---NPGTSSVSTTTSST---TTTTITTSSSRMQQPQISVYSGS 54
M + + + ST + + P P SS ++T S+T T+T +TTS+ P + +
Sbjct: 2387 MPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSI 2446
Query: 55 DRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQAS 114
PPS L M + + L + +S + + +S
Sbjct: 2447 PT-----------SPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASS 2495
Query: 115 LSSGRPSTSPTGSVTQQSSMSQTSINLSTSPT---PAQLISRSQASSS----TSGSITQQ 167
+ S + S TSI +ST+P A +S + S+ TS I+
Sbjct: 2496 SPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSS 2555
Query: 168 -TMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAA-------VQSDIPVVSSSSSSSCQ 219
T G++ PT T S+ LR+ + P + A V + IPV +S+ +SS
Sbjct: 2556 ATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSP 2615
Query: 220 SAATQ----VQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPS 275
+ A + + S L + S S + T S T +T VT+S + P+
Sbjct: 2616 TTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPT 2675
Query: 276 PESNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHH 335
+ + RST +T L+A + S + + V
Sbjct: 2676 TAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLS---------------TTPVDTS 2720
Query: 336 QLILQQQQQQIQPITLQ-NSTQDPPPSQHCIPLQN---HGLPPAPSNAQSQHCSPIQSHP 391
+ + P T + S + PS PL + LP A S A + + + +
Sbjct: 2721 TPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDT-S 2779
Query: 392 SPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQ--PGPNLQ 449
P+T S S S + V S P +PS++ T PL S + P + +
Sbjct: 2780 IPVTTSTEASSSPTTAEVTS-MPTSTPSETST------------PLTSMPVNHTPVASSE 2826
Query: 450 QSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSP--------SHQQY 501
T + + + +SP G V + S G +++ + +
Sbjct: 2827 AGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEA 2886
Query: 502 SSLQSSP----IPIASPPQMSTSP-PAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVS 556
S+L ++P IP+ + + S+SP A+ +P+ + +V + S +LV V+
Sbjct: 2887 STLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPS--EVSTPLTS---ILVSTVPVA 2941
Query: 557 EEELPAAEALVQLPFQTLPPPQTVA-----------VNLQVQPPAPVDPPVVYQVEDVCE 605
E A L P T P T A ++ + P P+ +
Sbjct: 2942 GSE---ASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLT----SMSV 2994
Query: 606 EEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKS 665
MP S E + RT P T +P + E P A + I +
Sbjct: 2995 STMPVASSEASTLSRT-PADTSTPVTTST-------------EASSSPTTAEGTGIPIST 3040
Query: 666 PSDPS----HVSVPPPPLLLPAATTRSNSTSMHSSIPSI 700
PS+ S + V P+ +P A+T S +T + S+ P +
Sbjct: 3041 PSEGSTPLTSIPVSTTPVAIPEASTLS-TTPVDSNSPVV 3078
Score = 63.9 bits (154), Expect = 7e-10
Identities = 162/792 (20%), Positives = 285/792 (35%), Gaps = 116/792 (14%)
Query: 17 PNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQY 76
P+ GT+ +++ STT + +++ P S + V +A PP++
Sbjct: 1155 PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDS------KTQVATSTEASSPPPTAEVTS 1208
Query: 77 LQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQ 136
+ ++ L + ++ ++SS+ +L STSP + T ++ ++
Sbjct: 1209 MPTSTPGERS-TPLTSMPVRHTPVASSEASTL------------STSPVDTSTPVTTSAE 1255
Query: 137 TSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTP 196
T S+SPT A+ S +S+TS T T + ST TL S A L+ TP
Sbjct: 1256 T----SSSPTTAE--GTSLPTSTTSEGSTLLTSIPVST--TLVTSP-----EASTLLTTP 1302
Query: 197 ATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLT 256
T PVV+S+ SS + A +S S +T +
Sbjct: 1303 VDTKG------PVVTSNEVSSSPTPAE---------------GTSMPTSTYSEGRTPLTS 1341
Query: 257 ICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTR------TSSIHQLIAPASYS 310
I N T V SS IS +P N + S E+ S+ T S+ + P +
Sbjct: 1342 IPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSI 1401
Query: 311 PIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQN-STQDPPPSQHCIPLQN 369
P+ ++ + L + P S + P T + S PS+ PL++
Sbjct: 1402 PVSTTPVVSSEASTLSATPVDTSTPG--TTSAEATSSPTTAEGISIPTSTPSEGKTPLKS 1459
Query: 370 ---HGLPPAPSNAQSQHCSPIQSHPSPLT---VSPNQSQSAQQSVVVSPPPPHS------ 417
P A S A + +P+ S+ +T VS + + + S+ +S P S
Sbjct: 1460 IPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSI 1519
Query: 418 PSQSPTIIIHPQALIQPHPLVSSA-------LQPGPNLQQSTANQVQATAQLNLP-SHLP 469
P + T+ + P V+S P T+ Q ++ + P + LP
Sbjct: 1520 PVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLP 1579
Query: 470 LPASPVV--HIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMS---TSPPAQ 524
+ VV + + + S Q S ++ + S + I++P + S TS P
Sbjct: 1580 VSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVS 1639
Query: 525 IPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNL 584
P+ +L P + ++ + VS PA + T ++ +
Sbjct: 1640 TTPVASPEASTLSTTP--VDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITV 1697
Query: 585 QVQPPA----------PVD--PPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAI 632
+ P A PVD PV E P S+ + TP T +I
Sbjct: 1698 RTTPVASSAISTLSTTPVDNSTPVTTSTE---ARSSPTTSEGTSMPNSTPSEGTTPLTSI 1754
Query: 633 TVGRGEDLTSEHPLLE--QVELPAVASVSASVIKSPSDPSHVSVPPPPL---LLPAATTR 687
V L+SE L ++ + S SP+ S+P L + P +T
Sbjct: 1755 PVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTP 1814
Query: 688 SNSTSMHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRP 747
+ T + +S S + P P + + + P P +S+ P +
Sbjct: 1815 VSHTLVANSEASTLSTTPVDSNSPVVTSTAVSS-------SPTPAEGTSIATSTPSEGST 1867
Query: 748 LLDNQVINSVCV 759
L + +++ V
Sbjct: 1868 ALTSIPVSTTTV 1879
Score = 60.5 bits (145), Expect = 8e-09
Identities = 146/779 (18%), Positives = 274/779 (35%), Gaps = 106/779 (13%)
Query: 1 MAEAEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQ 60
M + + + ST + + P S+ S+ +TT + TS I V + ++ +
Sbjct: 2564 MPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTS--------IPVTTSTETSSSP 2615
Query: 61 VIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRP 120
+ P S+ ++ + + + + A+ + LS++ + + V S +
Sbjct: 2616 TTAKDTSMPISTPSEVSTSLTSILVSTMPV--ASSEASTLSTTPVDTRTLVTTSTGTSSS 2673
Query: 121 STSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLL----GSTSP 176
T+ GS S+ + S L+ L++ S+AS+ ++ + T + S+SP
Sbjct: 2674 PTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSP 2733
Query: 177 TLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAA-TQVQNLTLRSQKL 235
T TA M + TP T++ S +PV SS +S+ +A T + T
Sbjct: 2734 T-TAEGTSMRISTPSDGSTPLTSILV--STLPVASSEASTVSTTAVDTSIPVTTSTEASS 2790
Query: 236 GVLSSSQNGPPKSTSQTQSLTICH---NKTTVTSSKISQRDPSPESNKKGESPSLESRST 292
++ P ST S + N T V SS+ +P + S ++ S+
Sbjct: 2791 SPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSS 2850
Query: 293 AVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQ 352
T + + + S + IP+ + P S + P+T
Sbjct: 2851 PTTAEGIVVPISTASEGSTLLT-------SIPVSTTPVASSEASTLSTTPVDTSIPVTTS 2903
Query: 353 NSTQDPP------------PSQHCIPLQN---HGLPPAPSNAQSQHCSPIQSHPSPLTVS 397
P PS+ PL + +P A S A + +P+ + +P+T S
Sbjct: 2904 TEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTR-TPVTTS 2962
Query: 398 PNQSQSAQQSV-----VVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQST 452
S S + + +P +P S ++ P A + L + + ST
Sbjct: 2963 AEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTST 3022
Query: 453 -ANQVQATAQ-LNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPI- 509
A+ TA+ +P P S + PV + + P + S+L ++P+
Sbjct: 3023 EASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIP----------EASTLSTTPVD 3072
Query: 510 ---PIASPPQMSTSP-PAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEA 565
P+ + ++S+SP PA+ +P+ + + V ++ +S +
Sbjct: 3073 SNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDT 3132
Query: 566 LVQLPFQT---LPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTP 622
+ T P + ++ P+ P+ Y E+S T
Sbjct: 3133 STPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTS 3192
Query: 623 PPPTLSPAAI--TVGRGEDLTSEHPLLEQVELPAV-------ASVSASVIKSP------- 666
P T S A T G + + P L +V AS AS++ +
Sbjct: 3193 TPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTP 3252
Query: 667 ---------------------SDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKP 704
S PS S P + + T S+ TS S+ P+ + P
Sbjct: 3253 LTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTP 3311
Score = 59.7 bits (143), Expect = 1e-08
Identities = 129/725 (17%), Positives = 275/725 (37%), Gaps = 66/725 (9%)
Query: 10 STAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRP 69
ST + T S + +ST TT T ++S S+ + + + + P
Sbjct: 3172 STMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSV---P 3228
Query: 70 PSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVT 129
S+ A + +L T + ++ ++ ++ + + P+++P+ T
Sbjct: 3229 VSNTP-------VASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGST 3281
Query: 130 QQSSMSQTSINLSTSPTPAQLISRSQASSST-----SGSITQQTMLLGSTSPTLTASQAQ 184
+SM ++ +++S T +S + A +ST S + + + G++ PT T S+
Sbjct: 3282 PLTSMPVSTTTVASSETST--LSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGS 3339
Query: 185 MYLRAQMLIFTPA-TTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQN 243
L TP ++ A+ S PV +S+ ++ A+ + T + S S+
Sbjct: 3340 TPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEAS--LSPTTAEGTSIPTSSPSEG 3397
Query: 244 GPPKSTSQTQSLTICHNKT-TVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQ 302
P ++ + + ++ T++++ + S + SP++ ++ T T+S +
Sbjct: 3398 TTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTS--E 3455
Query: 303 LIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQ-NSTQDPPPS 361
P S P+ + + L + P S + P T + S
Sbjct: 3456 GSTPLSIMPLSTTPVASSEASTLSTTPVDTSTP--VTTSSPTNSSPTTAEVTSMPTSTAG 3513
Query: 362 QHCIPLQNHGL---PPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSP 418
+ PL N + P A S A + +P+ S+ S +Q+ S+ ++ V+ +P
Sbjct: 3514 EGSTPLTNMPVSTTPVASSEASTLSTTPVDSNT--FVTSSSQASSSPATLQVTTMRMSTP 3571
Query: 419 SQSPTIIIHPQALIQPHPLVSSALQPG-PNLQQST--ANQVQATAQLNLPSHLPLPASPV 475
S+ + + L + S A P P++ +ST Q+ + P + LP S
Sbjct: 3572 SEGSSSLT-TMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTP 3630
Query: 476 VHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSP------------PA 523
+ VS +S + + + P+ + Q+S+SP P+
Sbjct: 3631 SEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPS 3690
Query: 524 Q----IPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQT 579
+ + +P+ + + + LS V+ + + E ++ A + ++ P
Sbjct: 3691 EGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPME 3750
Query: 580 VAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGED 639
++ + ++ V PE S + T T + + +
Sbjct: 3751 IST---------LGTTILVSTTPVTR--FPESSTPSIPSVYTSMSMTTASEGSSSPTTLE 3799
Query: 640 LTSEHPLL---EQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAAT-TRSNSTSMHS 695
T+ P+ E+ L +S + SPS+ S +S PP P T T++ S S+ +
Sbjct: 3800 GTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPA 3859
Query: 696 SIPSI 700
+ +I
Sbjct: 3860 EVTTI 3864
Score = 59.3 bits (142), Expect = 2e-08
Identities = 158/782 (20%), Positives = 290/782 (37%), Gaps = 109/782 (13%)
Query: 10 STAMDTEPNPGTSS-----VSTTTS-STTTTTITTSSSRMQQPQISVYSGS--DRHAVQV 61
+T+ + +P T+ +ST + ST T+I S++ + P+ S S + D ++ V
Sbjct: 2488 TTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVV 2547
Query: 62 IQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLS----- 116
+ +SA + L + + + L+SS+ +L+ S
Sbjct: 2548 TSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTT 2607
Query: 117 SGRPSTSPTG--------SVTQQSSMSQTSINLSTSP---TPAQLISRSQASSST----- 160
S S+SPT S + S S TSI +ST P + A +S + + T
Sbjct: 2608 STETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTS 2667
Query: 161 SGSITQQTMLLGSTSPTLTASQ-----AQMYLRAQMLIFTPATTVAA--VQSDIPVVSSS 213
+G+ + T GS+ PT T + + + +L + A+T++ V + PV +S+
Sbjct: 2668 TGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSA 2727
Query: 214 SSSSCQSAA--TQVQNLTLRSQKLGVLSSSQNGPPKSTSQ--TQSLTICHNKTTVTSSKI 269
+SS + A T ++ T + S + P ++S+ T S T VT+S
Sbjct: 2728 EASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTE 2787
Query: 270 SQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPA-----SYSPIQPHSLI----KH 320
+ P+ + + ST +T H +A + S +P+ + + K
Sbjct: 2788 ASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKA 2847
Query: 321 QQIPLHS-----PPSKVSHHQLILQQQQQQIQPI-TLQNSTQDPPPSQHCIPLQNHGLPP 374
P + P S S +L P+ + + ST P IP+
Sbjct: 2848 SSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPV------- 2900
Query: 375 APSNAQSQHCSPIQSHPSPLTVS-PNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQ 433
+ + SP + + + +S P++ + S++VS P + S++ T+ P
Sbjct: 2901 --TTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPV-AGSEASTLSTTPVDTRT 2957
Query: 434 PHPLVSSALQPGPNLQQSTANQVQATAQLNLP------SHLPLPASPVVHIG--PVQQSA 485
P S+ P + T+ + + P S +P+ +S + P S
Sbjct: 2958 P-VTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTST 3016
Query: 486 LVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMS---TSPPAQIPPLPLQSMQSLQVQPEI 542
V+ + S ++ + + IPI++P + S TS P P+ + +L P
Sbjct: 3017 PVTTSTEASSSP----TTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTP-- 3070
Query: 543 LSQGQVLVQNALVSEEELPA-------------AEALVQLPFQTLPPPQTVAVNLQVQPP 589
+ +V + VS PA + L +P T P + A++ P
Sbjct: 3071 VDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSS-AISTLSTTP 3129
Query: 590 APVDPPVVYQVEDVCEEEMPEESDECVRMDRTP----PPPTLSPAA--ITVGRGEDLTSE 643
PV E P S+ TP P T P + + V + S
Sbjct: 3130 VDTSTPVTTSTE---AHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSA 3186
Query: 644 HPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENK 703
P+ P S A+ + S + P + P + ++T + SS SI +
Sbjct: 3187 TPV--DTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILST 3244
Query: 704 PP 705
P
Sbjct: 3245 TP 3246
Score = 58.5 bits (140), Expect = 3e-08
Identities = 162/790 (20%), Positives = 283/790 (35%), Gaps = 93/790 (11%)
Query: 15 TEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRP---PS 71
+E + + V +T+ T++ I+T S+ V + ++ H+ + P PS
Sbjct: 3101 SEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPS 3160
Query: 72 SAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQ--LQSLAAVQASLSSGR--PSTSPTGS 127
+ L M + + + L + +S S A ++ + G P+++P+
Sbjct: 3161 EGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEG 3220
Query: 128 VTQQSSM---------SQTSINLSTSP----TPAQLISRSQASSSTSGSITQQTMLLGST 174
+T +S+ S+ SI LST+P TP + + +S T+ + T
Sbjct: 3221 MTPLTSVPVSNTPVASSEASI-LSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEG 3279
Query: 175 SPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLR--S 232
S LT+ A T +TT A + + S +SSS + T + T S
Sbjct: 3280 STPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGS 3339
Query: 233 QKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRST 292
L +S S S + T S T T VT+S + P + +G S S S
Sbjct: 3340 TPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSP---TTAEGTSIPTSSPSE 3396
Query: 293 AVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQ 352
T +S+ P S +P+ + + L + P V + L+ + P T+
Sbjct: 3397 GTTPLASM-----PVSTTPV-----VSSEVNTLSTTP--VDSNTLVTTSTEASSSP-TIA 3443
Query: 353 NSTQDP--PPSQHCIPLQNHGL---PPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQS 407
T P S+ PL L P A S A + +P+ + +P+T S + S +
Sbjct: 3444 EGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDT-STPVTTSSPTNSSPTTA 3502
Query: 408 VVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSH 467
V S P + S + P + P+ SS + ST + + + S
Sbjct: 3503 EVTSMPTSTAGEGSTPLTNMP---VSTTPVASS--------EASTLSTTPVDSNTFVTSS 3551
Query: 468 LPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPP 527
+SP + + S G ++ + + SS S P + S P
Sbjct: 3552 SQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTS- 3610
Query: 528 LPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQ 587
S PE+++ + + SE P T+ P T +V +
Sbjct: 3611 ---TQSNSTPTPPEVIT-----LPMSTPSEVSTPL----------TIMPVSTTSVTISEA 3652
Query: 588 PPA---PVD--PPVVYQVEDVCEEEMPEESDECV--RMDRTPPPPTLSPAAITVGRGEDL 640
A PVD PV+ + PE + + + + P T+ + V E
Sbjct: 3653 GTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGS 3712
Query: 641 TSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSI 700
T P + P S A + D + +SV P + TT ST+ + P
Sbjct: 3713 TLSTPSV-VTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPES 3771
Query: 701 ENKPPQAIVKPQILTHVIEGF---VIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSV 757
++ +T EG EG P+S +S ++ LL +I+ +
Sbjct: 3772 STPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTS-------ERSTLLTTVLISPI 3824
Query: 758 CVQPELQNNT 767
V + +T
Sbjct: 3825 SVMSPSEAST 3834
Score = 57.8 bits (138), Expect = 5e-08
Identities = 157/801 (19%), Positives = 281/801 (35%), Gaps = 123/801 (15%)
Query: 10 STAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRP 69
+T +DT PGT+S T+S TT I+ +S + + + S I +
Sbjct: 1418 ATPVDTS-TPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKS---------IPVSNTPV 1467
Query: 70 PSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVT 129
+S A L ++ TA +SSS + A + ST+ T
Sbjct: 1468 ANSEASTLSTTPVDSNSPVVTSTA------VSSSPTPAEGTSIAISTPSEGSTALTSIPV 1521
Query: 130 QQSSMSQTSIN-LSTSP----TPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQ 184
++++ + IN LST+P TP S++ +S +T+ + QT S LT+
Sbjct: 1522 STTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTS---- 1577
Query: 185 MYLRAQMLIFTPATTVAAVQSDIPVVSSS--SSSSCQSAATQVQNLTLRSQKLGVLSSSQ 242
P +T+ V S+ +S++ S + +A+T+ + T +S+
Sbjct: 1578 ----------LPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPS 1627
Query: 243 NGPPKSTSQTQSLT--ICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSI 300
G P TS S T +T++++ + P S + SP+ ++ T T +
Sbjct: 1628 EGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYT- 1686
Query: 301 HQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPP 360
+P+ I + + P S + P+T + P
Sbjct: 1687 ------EGRTPL--------TSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPT 1732
Query: 361 SQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQ 420
+ + P++ S+ +P+ S P++ +P S A ++ +P +P
Sbjct: 1733 TSEGTSM--------PNSTPSEGTTPLTS--IPVSTTPVLSSEA-STLSATPIDTSTPVT 1781
Query: 421 SPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGP 480
+ T + + +S L G + T+ V T N + L +PV P
Sbjct: 1782 TSTEATSSPTTAEGTSIPTSTLSEG--MTPLTSTPVSHTLVANSEAS-TLSTTPVDSNSP 1838
Query: 481 VQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMS---TSPPAQIPPLPLQSMQSLQ 537
V S VS SP+ + +S+ +S +P + S TS P + +L
Sbjct: 1839 VVTSTAVSS-----SPTPAEGTSIATS-----TPSEGSTALTSIPVSTTTVASSETNTLS 1888
Query: 538 VQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVV 597
P + S S + P + PP ++ V+
Sbjct: 1889 TTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVS-------------- 1934
Query: 598 YQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVAS 657
V E+ S D P T S A+ + + + P + P +
Sbjct: 1935 --TTTVASSEINTLSTTLA--DTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSM 1990
Query: 658 VSASVIKSPSDPSHVSVPPPPLLLPAAT--------TRSNSTSMHSSIPSIENKPPQAIV 709
++ + S+ S +S P PA T T + TS+ +S PS P +
Sbjct: 1991 PLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMP 2050
Query: 710 KPQILTHVIEGFVIQ--------------EGLEPFPVSRSSLLIEQPVKKRPLLDNQVIN 755
L EG + E SS+ I P + PLL + ++
Sbjct: 2051 VSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLS 2110
Query: 756 SVCV-QPELQN-NTKHADNSS 774
+ V PE +T D++S
Sbjct: 2111 TTPVASPEASTLSTTPVDSNS 2131
Score = 55.8 bits (133), Expect = 2e-07
Identities = 146/730 (20%), Positives = 263/730 (36%), Gaps = 71/730 (9%)
Query: 15 TEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAA 74
T PG SS T + + TT+ +TS S P + + S S +
Sbjct: 99 TSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESIS 158
Query: 75 QYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRP-------STSPTGS 127
+ + A +T+ + +S+ S QAS S P ST+ GS
Sbjct: 159 STMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTS---TQASSSPTTPESTTIPKSTNSEGS 215
Query: 128 VTQQSSMSQT-------SINLSTSP----TPAQLISRSQASSSTSGSITQQTMLLGSTSP 176
S + T +I L T+P TP + +++ +S +T+ + S
Sbjct: 216 TPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGST 275
Query: 177 TLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAA--TQVQNLTLRSQK 234
LT + L T +TT AA ++IPV++S+ +SS + A T + T
Sbjct: 276 PLTRMPLSVMLVVSSEASTLSTTPAA--TNIPVITSTEASSSPTTAEGTSIPTSTYTEGS 333
Query: 235 LGVLSSSQNGPPKSTSQ--TQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRST 292
+ S+ + P +TS+ T S+T T VT+S E SL + +
Sbjct: 334 TPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTST--------------EPSSLPTTAE 379
Query: 293 AVTR-TSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITL 351
A + TS++ + P + P+ + + + P V + + P T
Sbjct: 380 ATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIP--VDSKTFVTTASEASSSPTTA 437
Query: 352 QN-STQDPPPSQHCIPLQNHGL---PPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQS 407
++ S PS+ PL + + P A S A + +P+ S T ++ S+ +
Sbjct: 438 EDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTT--STEASSSPPT 495
Query: 408 VVVSPPPPHSPSQSPT------IIIHPQALIQPHPLVSSALQPG-PNLQQSTANQVQATA 460
V+ P +PS+ T + P A + L ++ + P S A+ T
Sbjct: 496 AEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTP 555
Query: 461 Q-LNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVS--PSHQQYSSLQSSPIPIASPPQM 517
+ ++P+ P S + PV +VS S P+ SS +S
Sbjct: 556 EGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAE 615
Query: 518 STSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLP-- 575
TS P ++ S+ V +++ + + + P + T
Sbjct: 616 GTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEG 675
Query: 576 ---PPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECV--RMDRTPPPPTLSPA 630
P T PV+ +V E P ++ V + + P T A
Sbjct: 676 TSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGA 735
Query: 631 AITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPS-HVSVPPPPLLLPAATTRSN 689
++ + ++ + + +S ++++ +P D S H++ P T +
Sbjct: 736 SMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSP---TTTE 792
Query: 690 STSMHSSIPS 699
TSM S PS
Sbjct: 793 GTSMPISTPS 802
Score = 54.7 bits (130), Expect = 4e-07
Identities = 179/922 (19%), Positives = 327/922 (35%), Gaps = 150/922 (16%)
Query: 4 AEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQ 63
AE + + +E +P +S+ +T+ + +T S+ V + ++ +
Sbjct: 1616 AEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPA 1675
Query: 64 QALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTS 123
+ P S+ + + + + + ++A+ LS++ + + V S + T+
Sbjct: 1676 EGTSMPTSTYTEGRTPLTSITVRTTPVASSAIST--LSTTPVDNSTPVTTSTEARSSPTT 1733
Query: 124 PTGSVTQQSSMSQ-----TSINLSTSP---TPAQLISRSQASSST-----SGSITQQTML 170
G+ S+ S+ TSI +ST+P + A +S + +ST + + + T
Sbjct: 1734 SEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTA 1793
Query: 171 LGSTSPTLTASQAQMYLRAQMLIFT-----PATTVAA--VQSDIPVVSSSSSSSCQSAA- 222
G++ PT T S+ L + + T A+T++ V S+ PVV+S++ SS + A
Sbjct: 1794 EGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE 1853
Query: 223 -TQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKK 281
T + T + S + ++S+T +L+ T+ + +Q SP +
Sbjct: 1854 GTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADG 1913
Query: 282 GESPSLESR-----------STAVTRTSSIHQL-------------IAPASYSPI----- 312
P+ R ST +S I+ L + AS SP
Sbjct: 1914 SSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGT 1973
Query: 313 -QPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNST---------------- 355
P PL S P + L++ + + + ST
Sbjct: 1974 SMPTPAYSEGSTPLTSMPLSTT---LVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAG 2030
Query: 356 ----QDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHP----SPLTVSPNQSQSAQ-- 405
Q PS+ PL G+P + + S + + + P + +T S S SA
Sbjct: 2031 GTSIQTSTPSERTTPLA--GMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAE 2088
Query: 406 -QSVVVSPPPPHSP-----SQSPTIIIHPQA-LIQPHP-------LVSSALQPGPNLQQS 451
S+ +S P SP S T + P+A + P + S+ + P +
Sbjct: 2089 GSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEG 2148
Query: 452 TANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPI 511
T+ Q + P +P S V V SA+ + V S +S ++ P
Sbjct: 2149 TSMQTSTYSDRRTPL-TSMPVSTTV----VASSAISTLSTTPVDTSTPVTNSTEARSSPT 2203
Query: 512 ASP-PQMSTSPPAQ----IPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEAL 566
S M TS P++ +P+ +M + + LS V + + E ++
Sbjct: 2204 TSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTT 2263
Query: 567 VQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDE--CVRMDRTPPP 624
+ T P T++ PV +V E P +S+ + + PP
Sbjct: 2264 AE---GTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPP 2320
Query: 625 PTLSPAAITVGRGEDLTSEHPLLEQ-VELPAVASVSASVI------------------KS 665
PT ++ + PL V VAS S + S
Sbjct: 2321 PTAEGTSMPTSTSSE--GNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSS 2378
Query: 666 PSDPSHVSVP--------PPPLLLPAAT--TRSNSTSMHSSIPSIENKPPQAIVKPQILT 715
P+ S+P P +P +T S+ S HS+ P + P +
Sbjct: 2379 PTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSP 2438
Query: 716 HVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQ--VINSVCVQPELQNNTKHADNS 773
EG I P ++ L PV P++ ++ +++ V T +S
Sbjct: 2439 TTAEGTSIPTSP---PSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASS 2495
Query: 774 SDTEMEDMIAEETLEEMDSELL 795
S T ED++ + S LL
Sbjct: 2496 SPTTAEDIVVPISTASEGSTLL 2517
Score = 43.9 bits (102), Expect = 8e-04
Identities = 137/709 (19%), Positives = 258/709 (36%), Gaps = 117/709 (16%)
Query: 10 STAMDTEPNPGTSSVSTTTSSTT------TTTITTSSSRMQQPQISVYSGSDRHAVQVIQ 63
+T+ T +P T+ V++ +ST T + S++ + + S S + + +
Sbjct: 3490 TTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVT 3549
Query: 64 QALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTS 123
+ S A + M + +++L LSS+ + S A S S ST
Sbjct: 3550 SSSQASSSPATLQVTTMRMSTPSE---GSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTP 3606
Query: 124 PTGSVTQQSSMSQTSINLSTSP--------TPAQLISRSQASSSTSGSITQQTMLLGSTS 175
T S QS+ + T + T P TP ++ S S + S + T T+ + +++
Sbjct: 3607 VTTST--QSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTST 3664
Query: 176 PTLTASQAQMY----LRAQMLIFTP---ATTVAAVQSDIPVVSSSSSSSCQSAATQVQNL 228
P +T++Q M I+TP +T + + V+SS S+ + +
Sbjct: 3665 PVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTP 3724
Query: 229 TLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLE 288
S + S++ + S S ++ V+++ +++ PES+ +PS+
Sbjct: 3725 VTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTR---FPESS----TPSIP 3777
Query: 289 SRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQP 348
S T+++ T+ AS P +L +P+ + + + +L I P
Sbjct: 3778 SVYTSMSMTT--------ASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVL------ISP 3823
Query: 349 ITLQN----STQDPPPSQHCIPL---QNHGLPPAPSNAQSQHCSPIQSHPSPLT---VSP 398
I++ + ST PP PL G P+ + S +PLT VS
Sbjct: 3824 ISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVST 3883
Query: 399 NQSQSAQQSVVVSPPP-----PHSPS----QSPTIIIHPQALIQPHPLVSSALQPGPNLQ 449
S + + S PP +PS +PTI P A +++ PG +
Sbjct: 3884 TLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTI---PVATTISVSVITEGSTPGTTIF 3940
Query: 450 QSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPI 509
+ +TA + P+ ++PV+ ++ +PS +S S+
Sbjct: 3941 IPSTPVTSSTADV-FPATTGAVSTPVI------------TSTELNTPS----TSSSSTTT 3983
Query: 510 PIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQL 569
++ + +T PL +M + P S+G S L A
Sbjct: 3984 SFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRG------CTTSASTLSAT------ 4031
Query: 570 PFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPP-----P 624
+ P T V P + P + P S TPP
Sbjct: 4032 ---STPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSS-------TPPTTSASS 4081
Query: 625 PTLSPAAITV----GRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDP 669
T++P A+T + T+ P + +P ++ ++ +P+ P
Sbjct: 4082 TTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVP 4130
Score = 43.1 bits (100), Expect = 0.001
Identities = 96/535 (17%), Positives = 193/535 (36%), Gaps = 57/535 (10%)
Query: 98 QHLSSSQLQSLAAVQASLSSGRP------STSPTGSVTQQSSMSQTSINLSTSPTPAQLI 151
QH+ + + A S + P ST+P + + S S T ST TP +
Sbjct: 57 QHVRTGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESR 116
Query: 152 SRSQASS-------STSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQ 204
+ S+++S S++ + T G+ P T S+ + + P + A
Sbjct: 117 TTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYT 176
Query: 205 SDIPVVSSS----SSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKST---SQTQSLTI 257
S V S +S+ S+ T ++ T+ S+ P ST + ++++T+
Sbjct: 177 SLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITL 236
Query: 258 CHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSL 317
+ S+ ++ + S E PSL + + + T P + P+ +
Sbjct: 237 LTTPVEI-STPVTISAQASSSPTTAEGPSLSNSAPSGGST--------PLTRMPLSVMLV 287
Query: 318 IKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQ-HCIPLQNHGLPPAP 376
+ + L + P+ + I IT ++ P ++ IP + P
Sbjct: 288 VSSEASTLSTTPAATN------------IPVITSTEASSSPTTAEGTSIPTSTYTEGSTP 335
Query: 377 SNAQSQHCSPI-QSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPH 435
+ P+ S S L+++P + + V S P P+ + +A
Sbjct: 336 LTSTPASTMPVATSEMSTLSITPVDTSTL---VTTSTEPSSLPTTA-------EATSMLT 385
Query: 436 PLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVS 495
+S P N+ ST + A+++ + S +P+ + V S+ + ++
Sbjct: 386 STLSEGSTPLTNMPVSTI--LVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIA 443
Query: 496 PSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALV 555
S S + +P+++ P +++S + + P+ S + E S N++
Sbjct: 444 TSTPSEGSTPLTSMPVSTTP-VASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMP 502
Query: 556 SEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPE 610
+ + L + T+P + A L P PV E PE
Sbjct: 503 TSTPSEGSTPLTSMSVSTMPVASSEASTLST-TPVDTSTPVTTSSEASSSSTTPE 556
Score = 38.5 bits (88), Expect = 0.032
Identities = 59/268 (22%), Positives = 98/268 (36%), Gaps = 40/268 (14%)
Query: 10 STAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRP 69
ST ++T P TSS STTTS +TT TT + P V + + +
Sbjct: 3968 STELNT---PSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTS 4024
Query: 70 PSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVT 129
S+ +A H S+S + V S S RPST + ++
Sbjct: 4025 AST-------------------LSATSTPHTSTS--VTTRPVTPSSESSRPSTITSHTIP 4063
Query: 130 QQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRA 189
+ +S +TS + + + + +T + +T + + T + +
Sbjct: 4064 PTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNP 4123
Query: 190 QMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAAT------QVQNLTLRSQKLGVLSSSQN 243
P TT +++S C++ T Q NL V+SS
Sbjct: 4124 TSTPTVPRTTTCFGDG-----CQNTASRCKNGGTWDGLKCQCPNLYYGELCEEVVSSIDI 4178
Query: 244 GPPKSTSQTQSLTICHNKTTVTSSKISQ 271
GPP++ S LT+ TVTS K ++
Sbjct: 4179 GPPETISAQMELTV-----TVTSVKFTE 4201
>gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens]
Length = 591
Score = 70.9 bits (172), Expect = 6e-12
Identities = 43/110 (39%), Positives = 61/110 (55%), Gaps = 10/110 (9%)
Query: 886 VPSAMTTRLRRQSERERERELRDVRIRKMPENSDLLPVAQTEPSIWTVDDVWAFIHSL-P 944
+P + + +RR R +R L E+ D ++ +PS WTV+DV F+ P
Sbjct: 488 LPPSTASAVRRLCSRGSDRYL---------ESRDASRLSGRDPSSWTVEDVMQFVREADP 538
Query: 945 GCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARINSLKE 994
AD FR EIDG+ALLLL+ D +M M +KLGPALK+ I+ LK+
Sbjct: 539 QLGPHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSYHIDRLKQ 588
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 69.3 bits (168), Expect = 2e-11
Identities = 143/624 (22%), Positives = 237/624 (37%), Gaps = 125/624 (20%)
Query: 16 EPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAA- 74
E T ++TTS T++TT T S + Q+ ++ SGS +++ P++
Sbjct: 1921 EQQKPTVIATSTTSPTSSTTSTISPA--QKVMVAPISGSVTTGTKMVLTTKVGSPATVTF 1978
Query: 75 ---QYLQQMYAAQQQHLMLHTAALQ-QQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQ 130
+ Q +A + ++ +Q QQ + S Q + +S +P T+
Sbjct: 1979 QQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPN 2038
Query: 131 QSSMSQTSIN--LSTSPT--PAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMY 186
S T+ N + T P P + R+ ST G +T P + A
Sbjct: 2039 TSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRT-------PVMVQPGAPQQ 2091
Query: 187 LRAQMLIFTPATTVAAVQSDIP-------VVSSSSSSSCQSAATQVQN-----LTLRSQK 234
+ Q++ P +T + + + + S++S+S+ QS+A+Q + L +
Sbjct: 2092 VMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQ 2151
Query: 235 LGVLSSSQNGPPKST-------SQTQSLTICHNKTTVTSSKISQRDPSPESNKKGE---- 283
L L+ G T T L + TV Q + N +
Sbjct: 2152 LTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLF 2211
Query: 284 SPSLESRSTAVTRTSSIHQLIAPAS---YSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQ 340
+P + +TA T T+++ A S + P + HQ L PP++ S
Sbjct: 2212 TPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQV-HQDKTL--PPAQSS------S 2262
Query: 341 QQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQ 400
+ QP T Q S Q P +Q P +P+ + Q +Q+ + + P++
Sbjct: 2263 VGPAEAQPQTAQPSAQPQPQTQ----------PQSPAQPEVQTQPEVQTQTTVSSHVPSE 2312
Query: 401 SQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATA 460
+Q P H+ S P V++ QP N+Q + +VQ+ +
Sbjct: 2313 AQ-----------PTHAQSSKPQ--------------VAAQSQPQSNVQGQSPVRVQSPS 2347
Query: 461 QLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTS 520
Q + P++P + +SPGQQ Q + S PIPI P S
Sbjct: 2348 QTRI-----RPSTP----------SQLSPGQQ------SQVQTTTSQPIPI--QPHTSLQ 2384
Query: 521 PPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTV 580
P+Q P QS +Q + LS GQ L Q VS P QL Q P PQ +
Sbjct: 2385 IPSQGQP---QSQPQVQSSTQTLSSGQTLNQ-VTVSSPSRP------QLQIQQ-PQPQVI 2433
Query: 581 AV---NLQVQPPAPVDPPVVYQVE 601
AV QVQ + + VV Q++
Sbjct: 2434 AVPQLQQQVQVLSQIQSQVVAQIQ 2457
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 69.3 bits (168), Expect = 2e-11
Identities = 140/636 (22%), Positives = 219/636 (34%), Gaps = 120/636 (18%)
Query: 112 QASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSI-----TQ 166
Q + +P P Q QT P P Q +++Q + +T GS T
Sbjct: 2526 QPQAAGSQPPAGPPAVQPQPQPQPQTQ------PQPVQAPAKAQPAITTGGSAAVLAGTI 2579
Query: 167 QTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDI--PVVSSSSSSSCQSAATQ 224
+T + G++ PT S + + PA T ++ + PV + ++ SA Q
Sbjct: 2580 KTSVTGTSMPTGAVSGNVI---VNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQ 2636
Query: 225 VQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGES 284
V + + +G P +T S+ VTS S + + + +
Sbjct: 2637 VVHTQPPPRAVG-------SPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPA 2689
Query: 285 PSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQ 344
SL + + T + I PA + L++ QQ + Q QQQQQ
Sbjct: 2690 RSLVPQVSQATGVQLPGKTITPAHFQ------LLRQQQQQQQQQQQQQQQQQQQQQQQQQ 2743
Query: 345 QIQPITLQNSTQDP-------PPSQ----------HCIPLQNHGL--PPAPSNAQSQHCS 385
Q Q T + Q P P+Q H I +Q L PP P Q+Q
Sbjct: 2744 QQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAP 2803
Query: 386 PIQSHPSPL-TVSPNQSQSAQQSVVVSPPP------------------------------ 414
P + + T P Q QS Q + V +P P
Sbjct: 2804 PQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQ 2863
Query: 415 --PHSPSQSPTIIIHPQALIQPHPLVSS-----------ALQPGPNLQQSTANQVQATAQ 461
+P + + P + P +VSS + Q A Q
Sbjct: 2864 MQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQP 2923
Query: 462 LNLPSHLPLPASPVVHIGPVQQSALVSP--------GQQIVSPSHQQYSSLQSSPIPIAS 513
+++ L L V +Q A P QQI +P QQ + + P A
Sbjct: 2924 VHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQP---AL 2980
Query: 514 PPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQT 573
Q T+P +Q L Q +Q Q ++ QV+ Q V+ + A A Q QT
Sbjct: 2981 KTQFLTTPISQAQ--KLAGAQQVQTQIQVAKLPQVVQQQTPVASIQ-QVASASQQASPQT 3037
Query: 574 LPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAIT 633
+ Q A QVQ P V V ++++ ++ + V P +P
Sbjct: 3038 VALTQATAAGQQVQM-----IPAVTATAQVVQQKLIQQ--QVVTTASAPLQTPGAPNPAQ 3090
Query: 634 VGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDP 669
V D S+ P L Q+ +PAV +K+P+ P
Sbjct: 3091 VPASSDSPSQQPKL-QMRVPAVR------LKTPTKP 3119
Score = 48.5 bits (114), Expect = 3e-05
Identities = 103/484 (21%), Positives = 164/484 (33%), Gaps = 79/484 (16%)
Query: 21 TSSVSTTTSSTTTTTITTSSSRMQQPQIS-VYSGSDRHAVQVIQQALHRPPSSAAQYLQQ 79
T V TS T + +TT+ + +Q P S V S VQ+ + + + QQ
Sbjct: 2663 TQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQ 2722
Query: 80 MYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPST----SPTGSVTQQS--S 133
QQQ QQQ Q + + VQ G+ + G +T +
Sbjct: 2723 QQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIK 2782
Query: 134 MSQTSINLSTSPTPAQL------------ISRSQASSSTSGSITQQT------MLLGSTS 175
M + + + P P Q + SQ S +T T +L G+T
Sbjct: 2783 MQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTV 2842
Query: 176 PTLTASQ------AQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLT 229
L ++ +Q+ + QM P A+ PVV S +A +T
Sbjct: 2843 ANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKP-PVV------SVPAAVVSSPGVT 2895
Query: 230 LRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLES 289
+ +S + P K+ QT H + + K+ Q+ +K P
Sbjct: 2896 TLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLL---KLKQQ---AVQQQKAIQPQAAQ 2949
Query: 290 RSTAVTRTSSIHQLIAPASYSPI----QPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQ 345
AV + + Q+ P + + QP + P+ S K++ QQ Q Q
Sbjct: 2950 GPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPI-SQAQKLAG----AQQVQTQ 3004
Query: 346 IQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQ 405
IQ L Q P A Q + SP TV+ Q+ +A
Sbjct: 3005 IQVAKLPQVVQQQTPV-----------------ASIQQVASASQQASPQTVALTQATAAG 3047
Query: 406 QSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLP 465
Q V + P+ + T + Q LIQ + +++ P N Q A + P
Sbjct: 3048 QQVQM------IPAVTATAQVVQQKLIQQQVVTTAS---APLQTPGAPNPAQVPASSDSP 3098
Query: 466 SHLP 469
S P
Sbjct: 3099 SQQP 3102
Score = 47.8 bits (112), Expect = 5e-05
Identities = 66/276 (23%), Positives = 104/276 (37%), Gaps = 32/276 (11%)
Query: 269 ISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSP 328
+ Q D E ++ E E +S + ++ + + S ++ L K QQ +
Sbjct: 418 LRQNDLDIEEEEEEEEEE-EEKSEVINDEQALAGSLVAGAGSTVET-DLFKRQQ----AM 471
Query: 329 PSKVSHHQLILQQQQQQIQPITLQNSTQDPP-PSQHCIPLQNHGLPPAPSNAQSQHCSPI 387
PS Q + + Q + Q+ D P Q +P G+PP P AQ
Sbjct: 472 PSTGMAEQSKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPPTPQAAQLAGQRQS 531
Query: 388 QSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPN 447
Q P T P Q + + P P P + P + P +SSALQ
Sbjct: 532 QQQYDPSTGPP-----VQNAASLHTPLPQLPGRLPPAGV-------PTAALSSALQFAQQ 579
Query: 448 LQQSTANQVQATAQLNLP-----SHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYS 502
Q V+A QL +P ++P+PA P + P+ S + +P Q
Sbjct: 580 PQ-----VVEAQTQLQIPVKTQQPNVPIPAPPSSQL-PIPPSQPAQLALHVPTPGKVQVQ 633
Query: 503 SLQSSPIP-IASPPQMSTSPPAQIP-PLPLQSMQSL 536
+ Q S +P + + ++ P P PLP S SL
Sbjct: 634 ASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSL 669
Score = 47.4 bits (111), Expect = 7e-05
Identities = 107/483 (22%), Positives = 164/483 (33%), Gaps = 95/483 (19%)
Query: 346 IQPITLQNSTQDPPPSQHCIPLQNHGL----PPAPSNAQSQHCSPIQSHPSPLTVSPNQS 401
I+P+ N Q P +H L G+ P P S I L
Sbjct: 2442 IKPLLGMNPFQKNP--KHASVLAESGINYDKPLPPIQVASLRAERIAKEKKALA----DQ 2495
Query: 402 QSAQQSVVVSPPPPHS-----PSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQ- 455
Q AQQ V PPPP P Q P + PQA P A+QP P Q T Q
Sbjct: 2496 QKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQP 2555
Query: 456 VQATAQ----LNLPSHLPLPASPV--------VHIGPVQQSALVSPGQQIVSPSHQQYSS 503
VQA A+ + + A + + G V + +V+ + + + Q +
Sbjct: 2556 VQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINK 2615
Query: 504 LQSSPIPIAS----------------PPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQ 547
+SP+ + PP + PA P L SM + Q + S
Sbjct: 2616 RLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATP-DLVSMATTQGVRAVTSVTA 2674
Query: 548 VLVQNALVSEEELPAAEAL--------VQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQ 599
V ++ + PA + VQLP +T+ P + Q Q Q
Sbjct: 2675 SAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQ 2734
Query: 600 VEDVCEEEMPEESDECVRMDRTP--PPPTLSPAAI-TVGRGEDLTSEH------------ 644
+ +++ ++ + P SPA I VG+ LT EH
Sbjct: 2735 QQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGK---LTPEHLIKMQKQKLQMP 2791
Query: 645 -----PLLEQVELPAVASVSASVIKSPSDPS----HVSVPPPPLLLPAATTRSNSTSMHS 695
P + A V + P S V+ P P LL T + + +
Sbjct: 2792 PQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLT 2851
Query: 696 SIPS--------IENKPPQ----AIVKPQILTHVIEGFVIQEGLEPFP--VSRSSLLIEQ 741
+P+ ++ + PQ A+ KP +++ V V G+ P V+ S+ I Q
Sbjct: 2852 RVPTSQLQAQGQMQTQAPQPAQVALAKPPVVS-VPAAVVSSPGVTTLPMNVAGISVAIGQ 2910
Query: 742 PVK 744
P K
Sbjct: 2911 PQK 2913
Score = 38.1 bits (87), Expect = 0.041
Identities = 42/146 (28%), Positives = 63/146 (43%), Gaps = 22/146 (15%)
Query: 397 SPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQ---QSTA 453
S + Q A + SP P +PS SP+ P IQ L++ + G N+ QS
Sbjct: 23 SEGEEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQIQ--QLMNRSPATGQNVNITLQSVG 80
Query: 454 NQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIAS 513
V Q+ L + LPLP+ SPG Q S +++ S I + S
Sbjct: 81 PVVGGNQQITL-APLPLPSP-------------TSPGFQF-SAQPRRFEHGSPSYIQVTS 125
Query: 514 P--PQMSTSPPAQIPPLPLQSMQSLQ 537
P Q+ T P Q P P Q++Q+++
Sbjct: 126 PLSQQVQTQSPTQPSPGPGQALQNVR 151
Score = 36.2 bits (82), Expect = 0.16
Identities = 83/386 (21%), Positives = 129/386 (33%), Gaps = 120/386 (31%)
Query: 419 SQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHI 478
S+ P + + Q ++ HP G LQQ + TAQ +P
Sbjct: 480 SKRPRLEVGHQGVVFQHP----GADAGVPLQQ-----LMPTAQGGMP------------- 517
Query: 479 GPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASP-----PQM-STSPPAQIPPLPLQS 532
P Q+A ++ +Q S QQY P+ A+ PQ+ PPA +P L S
Sbjct: 518 -PTPQAAQLAGQRQ----SQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSS 572
Query: 533 MQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPV 592
QP+++ A+ +Q+P +T QP P+
Sbjct: 573 ALQFAQQPQVVE------------------AQTQLQIPVKTQ------------QPNVPI 602
Query: 593 DPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVEL 652
P Q+ P P PA + L P QV+
Sbjct: 603 PAPPSSQL----------------------PIPPSQPAQLA------LHVPTPGKVQVQA 634
Query: 653 PAVASVSASVIKS--PSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVK 710
++S+ V + P DP+ PP P LP ++T S+ + S P + +
Sbjct: 635 SQLSSLPQMVASTRLPVDPA----PPCPRPLPTSST-SSLAPVSGSGPGPSPARSSPVNR 689
Query: 711 PQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQPELQNNTKHA 770
P T+ + L P ++ P K Q QN T
Sbjct: 690 PSSATN--------KALSPVTSRTPGVVASAPTKP--------------QSPAQNATSSQ 727
Query: 771 DNSSDTEMEDMIAEETLEEMDSELLK 796
D+S DT E + E + + +EL K
Sbjct: 728 DSSQDTLTEQITLENQVHQRIAELRK 753
Score = 35.4 bits (80), Expect = 0.27
Identities = 73/321 (22%), Positives = 104/321 (32%), Gaps = 60/321 (18%)
Query: 334 HHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSP 393
HH Q Q Q+Q ++ H P + P APS + S SP
Sbjct: 2 HHGTGPQNVQHQLQRSRACPGSEGEEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQIQQL 61
Query: 394 LTVSPNQSQS-------------AQQSVVVSPPPPHSPSQ---------------SPTII 425
+ SP Q+ Q + ++P P SP+ SP+ I
Sbjct: 62 MNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHGSPSYI 121
Query: 426 ---------IHPQALIQPHPLVSSALQ------PGPNL----QQSTANQVQATAQLNLPS 466
+ Q+ QP P ALQ PGP L T V A+ + S
Sbjct: 122 QVTSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQIS 181
Query: 467 HLP--------LPASPVVHIGPVQQSALVSPGQQIVSPSHQ--QYSSLQSSPIPIASPPQ 516
P S + I Q L PG I + Q + I P
Sbjct: 182 LSPSSGGHFVFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQS 241
Query: 517 MSTSPPAQIPPLPLQS-MQSLQVQPEILS--QGQVLVQNALVSEEELPAAEALVQLPFQT 573
+ + A + PL S + + + P+I S QGQ++ Q ++ LP + P
Sbjct: 242 PAAAGGAGLQPLASPSHITTANLPPQISSIIQGQLVQQQQVLQGPPLPRPLGFERTPGVL 301
Query: 574 LPPPQTVAVNLQVQPPAPVDP 594
LP A PP P P
Sbjct: 302 LPGAGGAAGFGMTSPPPPTSP 322
Score = 34.7 bits (78), Expect = 0.46
Identities = 75/356 (21%), Positives = 119/356 (33%), Gaps = 68/356 (19%)
Query: 69 PPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSV 128
PPS AA + + Q + + Q Q L + + V +L S P +
Sbjct: 35 PPSPAAPFAPSASPSAPQ-----SPSYQIQQLMNRSPATGQNVNITLQSVGPVVGGNQQI 89
Query: 129 TQQSSM--SQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMY 186
T S TS S P + S + + ++QQ T P+ QA
Sbjct: 90 TLAPLPLPSPTSPGFQFSAQPRRFEHGSPSYIQVTSPLSQQVQTQSPTQPSPGPGQALQN 149
Query: 187 LRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPP 246
+RA A + + SSS + A+ V+ ++L G
Sbjct: 150 VRA-----------GAPGPGLGLCSSSPTGGFVDASVLVRQISLSPSSGGHFVFQDGSGL 198
Query: 247 KSTSQTQSLTICHNKTTVTSSKISQRDPS-PESNKKGESPSLESRSTAVTRTSSIHQLIA 305
+Q + + H T +T + +R PS P + G L +S A + + L +
Sbjct: 199 TQIAQGAQVQLQHPGTPIT---VRERRPSQPHTQSGGTIHHLGPQSPAAAGGAGLQPLAS 255
Query: 306 PASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCI 365
P+ + + PP S Q L QQQQ +Q
Sbjct: 256 PSHITTA-------------NLPPQISSIIQGQLVQQQQVLQG----------------- 285
Query: 366 PLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQS 421
PP P P+ +P + P +A + SPPPP SPS++
Sbjct: 286 -------PPLPR--------PLGFERTPGVLLPGAGGAAGFGMT-SPPPPTSPSRT 325
Score = 34.3 bits (77), Expect = 0.60
Identities = 45/179 (25%), Positives = 70/179 (39%), Gaps = 41/179 (22%)
Query: 376 PSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPP-PHSPSQSPTIIIHPQALIQP 434
P++A S SP +HP+ L +AQ S PPP P +PS + PQ L+ P
Sbjct: 1501 PASASSTAASP--AHPAKLRAQT----TAQASTPGQPPPQPQAPSHAAGQSALPQRLVLP 1554
Query: 435 HPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIV 494
+Q QA LP+ VV I Q +++ P ++
Sbjct: 1555 -------------------SQAQAR----------LPSGEVVKI--AQLASITGPQSRVA 1583
Query: 495 SPSHQQYSSLQSSPIPIASPP--QMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQ 551
P Q S ++ Q++ P Q+ LQ + S QP + + G V++Q
Sbjct: 1584 QPETPVTLQFQGSKFTLSHSQLRQLTAGQPLQLQGSVLQ-IVSAPGQPYLRAPGPVVMQ 1641
Score = 34.3 bits (77), Expect = 0.60
Identities = 55/235 (23%), Positives = 97/235 (41%), Gaps = 29/235 (12%)
Query: 62 IQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSSSQ-LQSLAAVQASLSSGRP 120
I A+ +P +A Q + QQ L L A+QQQ Q Q AAVQ +++ +
Sbjct: 2904 ISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQI 2963
Query: 121 STSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTA 180
+T G+ + + +Q ++ TP IS++Q +G+ QT + + P +
Sbjct: 2964 TT--PGAQQKVAYAAQPALKTQFLTTP---ISQAQ---KLAGAQQVQTQIQVAKLPQVVQ 3015
Query: 181 SQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAA-TQVQNLTLRSQKLGVLS 239
Q T VA++Q V S+S +S Q+ A TQ + Q + ++
Sbjct: 3016 QQ---------------TPVASIQQ---VASASQQASPQTVALTQATAAGQQVQMIPAVT 3057
Query: 240 SSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAV 294
++ + Q Q +T + + P+ S+ + P L+ R AV
Sbjct: 3058 ATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPA-SSDSPSQQPKLQMRVPAV 3111
Score = 32.3 bits (72), Expect = 2.3
Identities = 38/161 (23%), Positives = 71/161 (44%), Gaps = 15/161 (9%)
Query: 33 TTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHT 92
T ++++ QQPQ+ + V+ Q + P ++Q + +Q L LH
Sbjct: 567 TAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQL--PIPPSQPAQLALHV 624
Query: 93 AALQQQHLSSSQLQSLAAVQASL------SSGRPSTSPTGSVTQQSSMSQTSINLSTSPT 146
+ + +SQL SL + AS + P PT S + + +S + P+
Sbjct: 625 PTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGS----GPGPS 680
Query: 147 PAQLISRSQASSSTS---GSITQQTMLLGSTSPTLTASQAQ 184
PA+ ++ SS+T+ +T +T + +++PT S AQ
Sbjct: 681 PARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQ 721
Score = 31.6 bits (70), Expect = 3.9
Identities = 100/460 (21%), Positives = 160/460 (34%), Gaps = 115/460 (25%)
Query: 141 LSTSPTPAQLISRSQASSSTSGSITQ-------QTMLLGSTSPTLTASQAQMYLRAQMLI 193
+STS PA + ++ +S Q +T+ ST P TA+
Sbjct: 1406 ISTSAAPAARPAAAKLKASRLFQPVQYGQKPEGRTVAFPSTHPPRTAA------------ 1453
Query: 194 FTPATTVAAVQSDI----PVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKST 249
P T AA Q + P+ + S++ ++AA Q SQ +S+ P S
Sbjct: 1454 --PTTASAAPQGPLRGRPPIATFSANPEAKAAAAPFQT----SQ---ASASAPRHQPASA 1504
Query: 250 SQTQSLTICHNK----TTVTSSKISQRDPSPE--SNKKGESPS-----LESRSTAVTRTS 298
S T + K TT +S Q P P+ S+ G+S L S++ A +
Sbjct: 1505 SSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVLPSQAQARLPSG 1564
Query: 299 SIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSK--VSHHQLILQQQQQQIQPITLQNSTQ 356
+ ++ AS + Q + L SK +SH QL +Q QP+ LQ S
Sbjct: 1565 EVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQL---RQLTAGQPLQLQGSVL 1621
Query: 357 DPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPH 416
+ AP P P P+ + A + S PP
Sbjct: 1622 Q--------------IVSAPGQ-------PYLRAPGPVVMQTVSQAGAVHGALGSKPPAG 1660
Query: 417 SPSQSP---------TIIIHPQALIQPHPLVSSALQP--GPNLQQSTANQVQATAQLNLP 465
PS +P + ++ A+ +P S P GP ++ T + Q+ L
Sbjct: 1661 GPSPAPLTPQVGVPGRVAVNALAVGEP-GTASKPASPIGGPTQEEKTRLLKERLDQIYLV 1719
Query: 466 SHLPLPASPVVHIGPVQQSALVSPGQ------------QIVSPSHQQYSSLQSSP----- 508
+ +PV ++ AL S G+ + P+H Y+S SP
Sbjct: 1720 NERRCSQAPVYGRDLLRICALPSHGRVQWRGSLDGRRGKEAGPAH-SYTSSSESPSELML 1778
Query: 509 ---------------IPIASPPQMSTSPPAQIP-PLPLQS 532
+ PP ++ P ++P P PL S
Sbjct: 1779 TLCRCGESLQDVIDRVAFVIPPVVAAPPSLRVPRPPPLYS 1818
>gi|5174669 sex comb on midleg-like 2 [Homo sapiens]
Length = 700
Score = 69.3 bits (168), Expect = 2e-11
Identities = 40/83 (48%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
Query: 914 MPENSDLLPVAQTEPSIWTVDDVWAFI-HSLPGCQD-IADEFRAQEIDGQALLLLKEDHL 971
+P+ S L +PS W+VD+V F+ H+ P +AD FR EIDG+AL LLK D +
Sbjct: 614 VPDPSVLKQGFSKDPSTWSVDEVIQFMKHTDPQISGPLADLFRQHEIDGKALFLLKSDVM 673
Query: 972 MSAMNIKLGPALKICARINSLKE 994
M M +KLGPALK+C I LKE
Sbjct: 674 MKYMGLKLGPALKLCYYIEKLKE 696
>gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens]
Length = 660
Score = 68.6 bits (166), Expect = 3e-11
Identities = 37/80 (46%), Positives = 50/80 (62%), Gaps = 1/80 (1%)
Query: 916 ENSDLLPVAQTEPSIWTVDDVWAFIHSL-PGCQDIADEFRAQEIDGQALLLLKEDHLMSA 974
E+ D ++ +PS WTV+DV F+ P AD FR EIDG+ALLLL+ D +M
Sbjct: 578 ESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKY 637
Query: 975 MNIKLGPALKICARINSLKE 994
M +KLGPALK+ I+ LK+
Sbjct: 638 MGLKLGPALKLSYHIDRLKQ 657
>gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens]
Length = 681
Score = 68.2 bits (165), Expect = 4e-11
Identities = 32/59 (54%), Positives = 42/59 (71%)
Query: 931 WTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARI 989
WTVDDV +F+ L GC + FR Q IDG+ L LL E+HL++ M +KLGPALKI A++
Sbjct: 543 WTVDDVCSFVGGLSGCGEYTRVFREQGIDGETLPLLTEEHLLTNMGLKLGPALKIRAQV 601
Score = 33.9 bits (76), Expect = 0.78
Identities = 69/296 (23%), Positives = 106/296 (35%), Gaps = 63/296 (21%)
Query: 324 PLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQH 383
P H PP + H L+ +Q+ + + + PS + GL A
Sbjct: 224 PWHDPPHHLPSHDLLRVRQEVAAAALRGPSGLEAHLPSSTAGQRRKQGLAQHREGA---- 279
Query: 384 CSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSAL- 442
+P + S + + PPP SP +P + + P L P V SAL
Sbjct: 280 -------------APAAAPSFSERELPQPPPLLSPQNAPHVALGPH-LRPPFLGVPSALC 325
Query: 443 -QPG-----PNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSP 496
PG P + A Q + + NL + L LPA ++Q L S Q+++P
Sbjct: 326 QTPGYGFLPPAQAEMFARQQELLRKQNL-ARLELPAD------LLRQKELESARPQLLAP 378
Query: 497 S-----HQQYSSLQ-----------SSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQP 540
+ LQ ++P+ +A PPQ PP PP P S S + P
Sbjct: 379 ETALRPNDGAEELQRRGALLVLNHGAAPL-LALPPQ---GPPGSGPPTP--SRDSARRAP 432
Query: 541 EILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPP-------PQTVAVNLQVQPP 589
G + + +E+ A Q + PP P+T AV + P
Sbjct: 433 RKGGPGPASARPS--ESKEMTGARLWAQDGSEDEPPKDSDGEDPETAAVGCRGPTP 486
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 66.6 bits (161), Expect = 1e-10
Identities = 99/410 (24%), Positives = 152/410 (37%), Gaps = 68/410 (16%)
Query: 306 PASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCI 365
P P+ P +L K Q PPS +S +++Q Q P PP+
Sbjct: 829 PTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPP-------PPTPPAMESQ 881
Query: 366 PLQNHGLPPAPSNAQSQHCSPIQSHPS--PLTV---SPNQSQSAQQSVVVSPPPPHSPSQ 420
PL+ P P+N Q +++ P P ++ SP+ +S +V PPPP SP
Sbjct: 882 PLK-----PVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVP 936
Query: 421 SPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGP 480
+P P P +S P P+ S + T++ + P P +P
Sbjct: 937 APP---------PPPPPTAS---PTPDKSGSPGKK---TSKTSSPGGKKPPPTP-----Q 976
Query: 481 VQQSALVSPGQQIVSPSHQQYSSLQSSPIPIA--SPPQMSTSPPAQIPPLPLQSMQSLQV 538
S S G + P SL S P A P T PP PP P + S
Sbjct: 977 RNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVN 1036
Query: 539 QPEILSQGQVLVQNALVSEE------ELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPV 592
P +L QG V + ++S E P+ + P PPP+T P P+
Sbjct: 1037 LPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFP---PPPPETEL------PLPPI 1087
Query: 593 DPPVVYQVEDVCEEEM--PEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQV 650
+ P V+ + + P+ + PPPT ++ L Q
Sbjct: 1088 EIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPT-----------RPKRNDSTRLTQA 1136
Query: 651 ELPAVASVSASVIKSPSDP-SHVSVPPPPLLLPAATTRSNSTSMHSSIPS 699
E+ +++ V + P+ P S +SV P L T + S + H S+ S
Sbjct: 1137 EISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSS 1186
Score = 66.2 bits (160), Expect = 1e-10
Identities = 99/426 (23%), Positives = 150/426 (35%), Gaps = 70/426 (16%)
Query: 274 PSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVS 333
P P +PS S + + S+I +L + +S L PP+
Sbjct: 644 PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGA------------LFKPPTPP- 690
Query: 334 HHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQ----HCSP--- 386
++Q Q + Q + N PPP PP P +A +Q C+P
Sbjct: 691 ----VMQSQSVKPQILVPPNGVVPPPPPPPP--------PPTPGSAMAQLKPAPCAPSLP 738
Query: 387 -IQSHPSPLTVSPNQSQSAQQSVVVSPPP---------PHSPSQSPTIIIHPQALIQPHP 436
+ P PL + +Q Q Q +PPP P +P + I P + P
Sbjct: 739 QFSAPPPPLKI--HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP 796
Query: 437 LVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPV-VHIGPVQQSALVSPGQQIVS 495
+V+ A P P A + A +P P P PV P QQS P +S
Sbjct: 797 VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS 856
Query: 496 PSHQQYSSLQSSPIPIASPPQMSTSP----PAQIPPLPLQSMQSLQVQPEILSQGQVLVQ 551
P + S P +PP M + P PA + P Q P + ++ +
Sbjct: 857 PVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAP---------QSPPAVKAKPKWQPS 907
Query: 552 NALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEE 611
+ V + P L F PPP + V P P PP D +
Sbjct: 908 SIPVPSPDFPPPPPESSLVFP--PPPPS-----PVPAPPPPPPPTASPTPDKSGSPGKKT 960
Query: 612 SDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSH 671
S + PPP ++I G +EHP ++ + ++ S +S S PS
Sbjct: 961 SKTSSPGGKKPPPTPQRNSSIKSSSG----AEHPEPKRPSVDSLVSKFTPPAESGS-PSK 1015
Query: 672 VSVPPP 677
++PPP
Sbjct: 1016 ETLPPP 1021
Score = 65.9 bits (159), Expect = 2e-10
Identities = 168/707 (23%), Positives = 254/707 (35%), Gaps = 99/707 (14%)
Query: 74 AQYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQ---SLAAVQASLS-------SGRPSTS 123
A+Y +Q+Y Q+ L +A LSSS ++ S +++ S S SG T
Sbjct: 503 AKYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQ 562
Query: 124 PTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSP------T 177
P G V QS +S T + S+++ S T L+ SP
Sbjct: 563 PAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMN----RPYTSLVPPLSPQPKIVTP 618
Query: 178 LTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAA------TQVQNLTLR 231
TASQ L P P + S S+ S SAA + + L
Sbjct: 619 YTASQPSPPLPPPPP--PPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNA 676
Query: 232 SQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRS 291
SQ G L P + + + V P+P S P+
Sbjct: 677 SQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA----- 731
Query: 292 TAVTRTSSIHQLIAPASYSPIQPHSLIKH--QQIPLHSPPSKVSHHQLILQQQQQQIQPI 349
S+ Q AP P++ H ++H Q P PP L Q + + I
Sbjct: 732 ---PCAPSLPQFSAPP--PPLKIHQ-VQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTI 785
Query: 350 TLQNSTQDPPP--SQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQS 407
ST+ P +Q P +PPA S P+P P + QQS
Sbjct: 786 PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQS 845
Query: 408 VVVSPPP-PHSPSQSPTIIIHPQALIQPHP--LVSSALQPGP-NLQQSTANQVQATAQLN 463
PPP P SP S I Q P P + S L+P P N+ + V+A +
Sbjct: 846 FCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ 905
Query: 464 LPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASP-PQMSTSPP 522
PS +P+P+ P +S+LV P P + P P ASP P S SP
Sbjct: 906 -PSSIPVPSPDFP--PPPPESSLVFP-----PPPPSPVPAPPPPPPPTASPTPDKSGSPG 957
Query: 523 AQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAV 582
+ ++ +P Q ++++ +E P ++ L + PP ++ +
Sbjct: 958 KKTS----KTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSP 1013
Query: 583 NLQVQPPAPVDPPVVYQVEDVCEEEMPEESDE-CVRMDRTPPPPTLSPAAITVGRGEDLT 641
+ + PP P PP ++ ++ +P + CV + A + GRG+D
Sbjct: 1014 SKETLPP-PAAPPKPGKL-NLSGVNLPGVLQQGCVS----------AKAPVLSGRGKDSV 1061
Query: 642 SEHPL-----------------LEQVELPAVASVSAS-----VIKSPSDPSHVSVPPPPL 679
E P L +E+PAV S + S V P S +SV P
Sbjct: 1062 VEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAP- 1120
Query: 680 LLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEG 726
P R++ST + + I +P A V PQ+ T +Q G
Sbjct: 1121 -PPTRPKRNDSTRLTQA--EISEQPTMATVVPQVPTSPKSSLSVQPG 1164
Score = 55.5 bits (132), Expect = 3e-07
Identities = 100/424 (23%), Positives = 143/424 (33%), Gaps = 94/424 (22%)
Query: 391 PSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPN-LQ 449
P P V+P + + PPPP P P P P SA P ++
Sbjct: 611 PQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP----PPPPPLPSQSAPSAGSAAPMFVK 666
Query: 450 QSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQ------YSS 503
ST ++Q +Q + P P PV+ V+ LV P + P +
Sbjct: 667 YSTITRLQNASQHSGALFKP-PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAM 725
Query: 504 LQSSPIPIA-SPPQMS----------------TSPPAQIPPLPLQSMQSLQVQPEIL--- 543
Q P P A S PQ S +PP PP P+ + Q P+ L
Sbjct: 726 AQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTI 785
Query: 544 -------SQGQVLVQNA-LVSEEELPAAEALVQLPFQTLPP-PQTVAVNLQVQPPAPVDP 594
+ V+ Q A +P A+ P +PP P T PP PV P
Sbjct: 786 PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPT--------PPVPVPP 837
Query: 595 PVVYQVEDVCEEEMPEESDECVRM-----DRTPPPPT--------LSPAAITVG-RGEDL 640
P + + + C + P + + PPPPT L P V +
Sbjct: 838 PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPA 897
Query: 641 TSEHPLLEQVELPAVA------SVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTS-- 692
P + +P + +S++ P PS V PPPP A+ T S S
Sbjct: 898 VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPG 957
Query: 693 ---MHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLL 749
+S P + PP PQ + + +SS E P KRP +
Sbjct: 958 KKTSKTSSPGGKKPPP----TPQRNSSI----------------KSSSGAEHPEPKRPSV 997
Query: 750 DNQV 753
D+ V
Sbjct: 998 DSLV 1001
Score = 48.9 bits (115), Expect = 2e-05
Identities = 90/405 (22%), Positives = 147/405 (36%), Gaps = 97/405 (23%)
Query: 394 LTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSS----ALQPGPNLQ 449
L+ S +S S+ S+ S + S S P ++ +VSS A + G L+
Sbjct: 529 LSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLE 588
Query: 450 QSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSP- 508
+S+ ++++ +N P +P +SP +IV+P Y++ Q SP
Sbjct: 589 ESSKARMES---MNRPYTSLVPP--------------LSPQPKIVTP----YTASQPSPP 627
Query: 509 IPIASPPQMSTSPPAQIPPLPLQSMQS----------------LQVQPEILSQGQV---- 548
+P PP PP PP PL S + ++Q G +
Sbjct: 628 LPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP 687
Query: 549 ---LVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQP----------PAPVDPP 595
++Q+ V + L +V P PPP + Q++P AP P
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPL 747
Query: 596 VVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPA----------AITVGRGEDLTSEHP 645
++QV+ + + P TPPPP PA +T+ + P
Sbjct: 748 KIHQVQHITQVAPP-----------TPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP 796
Query: 646 LLEQVELPAVASVSASVIKSPSDPSHV---SVPPPPLLLPAATTRSNSTSMHSSIPSIEN 702
++ Q P K P+ P+ S P PP+ +P T S
Sbjct: 797 VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQ--------SFCA 848
Query: 703 KPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRP 747
KPP + + P + V++ Q P P + S QP+K P
Sbjct: 849 KPPPSPLSP--VPSVVKQIASQFPPPPTPPAMES----QPLKPVP 887
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 65.9 bits (159), Expect = 2e-10
Identities = 129/587 (21%), Positives = 203/587 (34%), Gaps = 75/587 (12%)
Query: 126 GSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQM 185
G+ +S+ S P + A +++ G ++ G+T P Q +
Sbjct: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG-PLGQKGL 125
Query: 186 YLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGP 245
+ A+ + T A +S + + +S + T + RS+ G
Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSG-PTPGTPSPAMARRSRAAGTEVGLPR-- 182
Query: 246 PKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIA 305
P +++ + T K+ ++S+ S +PSP + ++ + R + + +SS L +
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242
Query: 306 PASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCI 365
PA P P +H + Q ++P Q PP +
Sbjct: 243 PARSGP------------SARGTPRAPAHPSQPKPKGLQALRP------PQVTPPRKDAA 284
Query: 366 PLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTII 425
P L P S SP+ + PSP S S SA S+ P PP +P T
Sbjct: 285 P----ALGPLSS-------SPLAT-PSP---SAPPSPSAPPSLQTLPSPPATPPSQATTS 329
Query: 426 IHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSA 485
+ L H + P P L QA L LP PL A P P S
Sbjct: 330 LGSPTLQATHSFL-----PSPPLSPLATPPPQAPPALALP---PLQAPPSPPASP-PLSP 380
Query: 486 LVSPGQQIVSPSHQQYSSLQSSPIPIASPP-QMSTSPPAQIPPLPLQSMQSLQVQPEILS 544
L +P Q +P+ LQ+ P SPP Q SPPA PP+ + Q P + +
Sbjct: 381 LATPSPQ--APNALAVHLLQAPFSPPPSPPVQAPFSPPAS-PPVSPSATPPSQAPPSLAA 437
Query: 545 QGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVC 604
+ + S P+A Q P PP +A PPA PP+
Sbjct: 438 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 497
Query: 605 E--EEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASV 662
+ P + M PP +P + PLL+ P + +
Sbjct: 498 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAA----------PLLQVPPSPPASPTLQAP 547
Query: 663 IKSPSDPSHVSV-------------PPPPLLLPAATTRSNSTSMHSS 696
+ P+ SV PPPP P++T + HSS
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 594
Score = 49.3 bits (116), Expect = 2e-05
Identities = 89/390 (22%), Positives = 135/390 (34%), Gaps = 50/390 (12%)
Query: 109 AAVQASLSSGRPSTSPTGSVT-QQSSMSQTSINLSTSPTPA------------QLISRSQ 155
A + L PS P + S+S S + +T P+PA + SRS
Sbjct: 174 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233
Query: 156 ASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSS 215
+SS+T S ++ +P A +Q + + P T + P + SS
Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA-APALGPLSS 292
Query: 216 SSCQSAATQVQNLTLRSQKLGVLSSSQNGPP-KSTSQTQSLTICHNKTTVTSSKIS---- 270
S + + L L S PP ++T+ S T+ + + S +S
Sbjct: 293 SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 352
Query: 271 --------------QRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHS 316
Q PSP ++ SP L + S ++H L AP S P P
Sbjct: 353 PPPQAPPALALPPLQAPPSPPASPP-LSP-LATPSPQAPNALAVHLLQAPFSPPPSPPVQ 410
Query: 317 L-----IKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHG 371
P +PPS+ Q P + S PP Q PL
Sbjct: 411 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 470
Query: 372 LP---PAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHP 428
L P P + P+Q+ PSP P Q+ + + + P P Q+P ++ P
Sbjct: 471 LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 530
Query: 429 QALIQPHPLVSSALQ-------PGPNLQQS 451
+ P P S LQ PGP+ S
Sbjct: 531 LLQVPPSPPASPTLQAPRRPPTPGPDTSVS 560
>gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens]
Length = 755
Score = 65.1 bits (157), Expect = 3e-10
Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 4/74 (5%)
Query: 916 ENSDLLPVAQTEP----SIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHL 971
+ S LLP P S W+ D+V FI SLPGC++ F+ ++IDG+A LL+ + +
Sbjct: 664 QQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDI 723
Query: 972 MSAMNIKLGPALKI 985
+ M+IKLGPALKI
Sbjct: 724 VKIMSIKLGPALKI 737
Score = 30.4 bits (67), Expect = 8.6
Identities = 24/117 (20%), Positives = 45/117 (38%), Gaps = 15/117 (12%)
Query: 797 CEFCGKMGYANEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGP 856
CE C + G +E L +C+ +CA+ K+ + + DN+ + R P
Sbjct: 95 CENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKE----ERDVEEDNEEEDPKCSRKKKP 150
Query: 857 DGAAREHILRQLPITYPSAEEDLASHEDSVPSAMTTRLRRQSERERERELRDVRIRK 913
+ + +ED +D + + R+ R S+R R + D + K
Sbjct: 151 KLSLK-----------ADTKEDGEERDDEMENKQDVRILRGSQRARRKRRGDSAVLK 196
>gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens]
Length = 780
Score = 65.1 bits (157), Expect = 3e-10
Identities = 33/74 (44%), Positives = 47/74 (63%), Gaps = 4/74 (5%)
Query: 916 ENSDLLPVAQTEP----SIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHL 971
+ S LLP P S W+ D+V FI SLPGC++ F+ ++IDG+A LL+ + +
Sbjct: 689 QQSKLLPTVAGIPASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDI 748
Query: 972 MSAMNIKLGPALKI 985
+ M+IKLGPALKI
Sbjct: 749 VKIMSIKLGPALKI 762
Score = 30.4 bits (67), Expect = 8.6
Identities = 24/117 (20%), Positives = 45/117 (38%), Gaps = 15/117 (12%)
Query: 797 CEFCGKMGYANEFLRSKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGP 856
CE C + G +E L +C+ +CA+ K+ + + DN+ + R P
Sbjct: 120 CENCCQYGNVDECLSGGNYCSQNCARHIKDKDQKE----ERDVEEDNEEEDPKCSRKKKP 175
Query: 857 DGAAREHILRQLPITYPSAEEDLASHEDSVPSAMTTRLRRQSERERERELRDVRIRK 913
+ + +ED +D + + R+ R S+R R + D + K
Sbjct: 176 KLSLK-----------ADTKEDGEERDDEMENKQDVRILRGSQRARRKRRGDSAVLK 221
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 64.7 bits (156), Expect = 4e-10
Identities = 120/482 (24%), Positives = 178/482 (36%), Gaps = 72/482 (14%)
Query: 232 SQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRS 291
S L S PP+ + + +L T S SP + SP E
Sbjct: 509 SSPFSPLEESPLSPPEESPPSPALE------TPLSPPPEASPLSPPFEESPLSPPPEELP 562
Query: 292 TAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITL 351
T+ +S +L P SP+ P ++ P+ SPP + S +L ++ + P
Sbjct: 563 TSPPPEAS--RLSPPPEESPMSPPP----EESPM-SPPPEAS--RLFPPFEESPLSPPPE 613
Query: 352 QNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVS 411
++ PP + P P P S SPL V S ++S +S
Sbjct: 614 ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEES-PLS 672
Query: 412 PPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSH---- 467
PPP SP+ P P+A P S P P + S A+ + ++LP
Sbjct: 673 PPPEESPTSPP-----PEASRLSPPPEDSPTSPPP--EDSPASPPPEDSLMSLPLEESPL 725
Query: 468 LPLPASPVV-------HIGPVQQSALVS--PGQQIVSPSHQQ--YSSLQSSPIPIASPPQ 516
LPLP P + H+ P + +S P + +SP ++ S P A P +
Sbjct: 726 LPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE 785
Query: 517 MSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPP 576
SP A+ P L QPE L + L +P L P ++
Sbjct: 786 PHLSPQAEGP--------HLSPQPEELHLSPQTEEPHL---SPVPEEPCLSPQPEESHLS 834
Query: 577 PQTVAVNLQVQP-PAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTP--PP---PTLSPA 630
PQ+ L +P + + P + E+ PEE +C + P PP P+LSP
Sbjct: 835 PQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPL 894
Query: 631 AITVGRGEDLTSE------HPLLEQVELPAVASVSASVIKSPSDPSHVSVPPP--PLLLP 682
GE SE PL E++ L S S P DP +PPP P++
Sbjct: 895 L-----GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDP----LPPPLSPIITA 945
Query: 683 AA 684
AA
Sbjct: 946 AA 947
Score = 63.9 bits (154), Expect = 7e-10
Identities = 96/380 (25%), Positives = 146/380 (38%), Gaps = 49/380 (12%)
Query: 269 ISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSP 328
+S R P + + E P L ++ + + A P +PH L + P SP
Sbjct: 743 LSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV--PEEPH-LSPQAEGPHLSP 799
Query: 329 PSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHG-LPPAPSNAQSQHCSPI 387
+ H L Q ++ + P+ + P H P L P P + H SP
Sbjct: 800 QPEELH--LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP---EESHLSPE 854
Query: 388 QSHPSPLTVSPNQ-----SQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSAL 442
P PL+ P + Q + PPP PS SP ++ AL +P L
Sbjct: 855 LEKP-PLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSP--LLGEPALSEPG---EPPL 908
Query: 443 QPGPN-LQQSTANQVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQY 501
P P L S + + + QL P LP P SP++ +SP ++ P +
Sbjct: 909 SPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPII---TAAAPPALSPLGELEYPFGAKG 965
Query: 502 SSLQSSPI-------PIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNAL 554
S SP+ PI+ PP+ + + P +PP+ L V P + +
Sbjct: 966 DSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGP----------ASPI 1015
Query: 555 VSEEELPAAEALVQ--LPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEE-EMPEE 611
+ E P L+Q L Q PP Q L + P+P+ P + +V V +E E+ E
Sbjct: 1016 LMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSP--IGKVVGVSDEAELHEM 1073
Query: 612 SDECVRMDRTPPPPTLSPAA 631
E V P P L P+A
Sbjct: 1074 ETEKV---SEPECPALEPSA 1090
Score = 58.2 bits (139), Expect = 4e-08
Identities = 126/558 (22%), Positives = 195/558 (34%), Gaps = 79/558 (14%)
Query: 41 SRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHL 100
S +QQ +S +SG + + Q + Q QQ+ QQQ L LQQQ L
Sbjct: 3874 SHLQQSLMS-HSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQ-QQQQLQQQQL 3931
Query: 101 SSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSST 160
Q Q Q + + QQ Q L+++S+ S
Sbjct: 3932 QQQQQQQ----QLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSP 3987
Query: 161 SGSITQQTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQS 220
QQ L P + A Q + L T T + P VSS ++
Sbjct: 3988 QQQQQQQVAL----GPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEG--P 4041
Query: 221 AATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNK 280
+ Q L + + + + P + +Q L + Q P P+ +
Sbjct: 4042 STHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLV-------------QPQPQPQPSS 4088
Query: 281 KGESPSLESRSTAVTRTSSIH--------QLIAPASYSPIQPHSLIKHQQIPLHSPPSKV 332
P L + S +H QL + +S L+ + L P +
Sbjct: 4089 LQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSM 4148
Query: 333 SHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLP-----PAPSNAQSQHCSPI 387
+ Q +L QQ ++ +QN+T PP + GLP P ++Q +
Sbjct: 4149 T--QNLLGPQQPMLER-PMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVL 4205
Query: 388 QSHPSPLTVSPNQSQ---------SAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLV 438
+P +SP Q Q QQS V PP+ + T + Q L+ P +
Sbjct: 4206 AKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPL--QGLLGCQPQL 4263
Query: 439 SSALQPGPNLQQSTANQVQATAQLNLPSHLPLP-----ASPVVHIGPVQQSALVSPGQ-- 491
PGP Q ++ A + P LP P PV +GPV + S Q
Sbjct: 4264 GGF--PGP--QTGPLQELGAGPRPQGPPRLPAPPGALSTGPV--LGPVHPTPPPSSPQEP 4317
Query: 492 ----QIVSPSHQQYSSLQSSPIPIASP-PQMST--SPPAQIPPLPLQSMQSLQVQ----- 539
Q+ SPS Q + Q P +P PQ T PP ++ P Q +L +
Sbjct: 4318 KRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPW 4377
Query: 540 --PEILSQGQVLVQNALV 555
P+ L++ Q Q++LV
Sbjct: 4378 DPPDNLAETQKPEQSSLV 4395
Score = 57.8 bits (138), Expect = 5e-08
Identities = 95/403 (23%), Positives = 155/403 (38%), Gaps = 56/403 (13%)
Query: 358 PPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHP-SPLTVSPNQSQSAQQSVVVSPPPPH 416
PPP + + P +P S+ P + P SPL + + S+ ++S +SPPP
Sbjct: 442 PPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESP-LSPPPEE 500
Query: 417 SPSQSP----------TIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPS 466
SP P + P P P + + L P P + S + + L+ P
Sbjct: 501 SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP--EASPLSPPFEESPLSPPP 558
Query: 467 HLPLPASP---VVHIGPVQQSALVS--PGQQIVSP---SHQQYSSLQSSPI-------PI 511
LP SP + P + + +S P + +SP + + + + SP+ P+
Sbjct: 559 E-ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPL 617
Query: 512 ASPPQMS--TSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNAL-VSEEELPAAEALVQ 568
+ PP+ S + PP P P + PE+ + V + L EE P + +
Sbjct: 618 SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEE 677
Query: 569 LPFQTLPPPQTVAV-----NLQVQPP---APVDPPVVYQVEDVCEEE-----MPEESDEC 615
P T PPP+ + + PP +P PP + + EE +PEE C
Sbjct: 678 SP--TSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLC 735
Query: 616 VR-----MDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSP-SDP 669
R + P P LSP H L Q E P + +V SP ++
Sbjct: 736 PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPH-LSPQPEEPCLCAVPEEPHLSPQAEG 794
Query: 670 SHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQ 712
H+S P L L T + + + P + +P ++ + PQ
Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEE-PCLSPQPEESHLSPQ 836
Score = 55.1 bits (131), Expect = 3e-07
Identities = 124/598 (20%), Positives = 204/598 (34%), Gaps = 108/598 (18%)
Query: 120 PSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLL-------- 171
P SPT + S +S + TSP P + S +++ LL
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734
Query: 172 --GSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLT 229
S P L+ + +L + P + Q++ P +S C A + +L
Sbjct: 735 CPRSEGPHLSPRPEEPHLSPR-----PEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL- 788
Query: 230 LRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQR---DPSPES---NKKGE 283
S Q P + Q + L + S + + P PE + + E
Sbjct: 789 ----------SPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE 838
Query: 284 SPSLESRSTAVTRTSSIHQ--LIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQ 341
P L R + + + L P +P +++PL PP + S
Sbjct: 839 EPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPS-------- 890
Query: 342 QQQQIQPITLQNSTQDP--PPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPN 399
+ P+ + + +P PP PL LP +PS S + P P +SP
Sbjct: 891 ----LSPLLGEPALSEPGEPPLS---PLPEE-LPLSPSGEPSLSPQLMPPDPLPPPLSP- 941
Query: 400 QSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPH-----PLVSSALQPGPNLQQSTAN 454
+ + PP SP + P P++ + + P P ++
Sbjct: 942 -------IITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPP---EANCT 991
Query: 455 QVQATAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASP 514
+ + LP P P SPV P+ L+ P SP Q Q+SP SP
Sbjct: 992 DPEPVPPMILP---PSPGSPVGPASPI----LMEPLPPQCSPLLQHSLVPQNSPPSQCSP 1044
Query: 515 PQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTL 574
P + S P+ P P+ + + + E+ ++ VSE E PA E P T
Sbjct: 1045 PALPLSVPS--PLSPIGKVVGVSDEAELHE-----METEKVSEPECPALE-----PSATS 1092
Query: 575 PPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITV 634
P P + + PAP P + + E+ P + + + P P +P ++
Sbjct: 1093 PLPSPMG---DLSCPAPSPAPALDDFSGLGEDTAPLDG---IDAPGSQPEPGQTPGSL-- 1144
Query: 635 GRGEDLTSEHPLLEQVELPAVASV-----------SASVIKSPSDPSHVSVPPPPLLL 681
+L LL+ EL V + S + +P P PP L+
Sbjct: 1145 --ASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLI 1200
Score = 54.3 bits (129), Expect = 6e-07
Identities = 167/760 (21%), Positives = 252/760 (33%), Gaps = 111/760 (14%)
Query: 53 GSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHL-MLHTAALQQQHLSSSQLQSLAAV 111
G D +Q Q L + AQ LQQ QQQ +L A+QQQ +Q+ A+
Sbjct: 3710 GPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQAL 3769
Query: 112 QASLSSGRPSTSPTGSVTQQSS------------MSQTSINLSTSP------TPAQLISR 153
P +S G + QQ S +Q ++ P P + +
Sbjct: 3770 GPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLM 3829
Query: 154 SQASSSTSGSITQQTM-LLGSTSPTLTASQAQMYLRAQ--MLIFTPATTVAAVQSDIPVV 210
+Q+ +S + QQ L+G T Q Q + Q M + S P +
Sbjct: 3830 TQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKL 3889
Query: 211 SSSSSSSC------------QSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTIC 258
S+ S Q Q Q + Q+L Q + Q Q +
Sbjct: 3890 SAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ 3949
Query: 259 HNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLI 318
+ + + Q+ + ++ + L T ++ Q +A P +P +
Sbjct: 3950 QQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKP---L 4006
Query: 319 KHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSN 378
+H S P + L+ ++Q + P +T+ P Q PL G P
Sbjct: 4007 QH-----FSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGG-PLA-IGTTPESMA 4059
Query: 379 AQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVVSPPPPHSPSQSPTI-IIH---------- 427
+ P S S L + Q Q S+ + PP Q + ++H
Sbjct: 4060 TEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQL 4119
Query: 428 -----PQALIQPH----PLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPASPVVHI 478
+A PH P VS QPG Q Q + + P P P
Sbjct: 4120 GSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKP---- 4175
Query: 479 GPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQV 538
GPV QS PG I+ Q + LQ +A PQ+ P Q Q +Q+L +
Sbjct: 4176 GPVLQSGQGLPGVGIMPTVGQLRAQLQG---VLAKNPQLRHLSPQQ-----QQQLQALLM 4227
Query: 539 QPEILSQGQVLVQNALVSEEELPAAEALVQLPFQT----LPPPQTVAVNLQVQPPAPVDP 594
Q + L Q Q + Q E + L Q P PQT + P P P
Sbjct: 4228 QRQ-LQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP 4286
Query: 595 PVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPA 654
P + S V P PP SP R L S +LP
Sbjct: 4287 PRLPAPPGAL-------STGPVLGPVHPTPPPSSPQ--EPKRPSQLPS-----PSSQLPT 4332
Query: 655 VASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIP-------SIENKPPQA 707
A + + +P PPP + PAA +++ P + KP Q+
Sbjct: 4333 EAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQS 4392
Query: 708 IVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRP 747
+ P L V G V+ E S L I+Q ++ P
Sbjct: 4393 SLVPGHLDQV-NGQVVPEA--------SQLSIKQEPREEP 4423
Score = 51.2 bits (121), Expect = 5e-06
Identities = 79/321 (24%), Positives = 125/321 (38%), Gaps = 50/321 (15%)
Query: 375 APSNAQSQHCSPIQSHPSPLTVSPNQSQSAQ--QSVVVSPPPPHSPSQSPTIIIHPQALI 432
AP N + P + SPL+ P +S ++ ++ +SPPP P+ SP P+AL
Sbjct: 432 APLNEEMPLLPPPEE--SPLSPPPEESPTSPPPEASRLSPPPEELPA-SPL----PEALH 484
Query: 433 QPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPL------PASPVVH--IGPVQQS 484
PL S L P P ++S + ++ + PL P SP + + P ++
Sbjct: 485 LSRPLEESPLSPPP--EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA 542
Query: 485 ALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMS--TSPPAQIPPLPLQSMQSLQVQPEI 542
+ +SP P + S +P + PP+ S + PP + P P + PE
Sbjct: 543 SPLSP------PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE- 595
Query: 543 LSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVED 602
EE P + + P PPP+ ++ P P D P+ E+
Sbjct: 596 -------ASRLFPPFEESPLSPPPEESPLS--PPPEASRLS-----PPPEDSPMSPPPEE 641
Query: 603 VCEEEMPEES--DECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSA 660
PE S + R PPP SP ++ E TS P ++ P S ++
Sbjct: 642 SPMSPPPEVSRLSPLPVVSRLSPPPEESP--LSPPPEESPTSPPPEASRLSPPPEDSPTS 699
Query: 661 SVIKSPSDPSHVSVPPPPLLL 681
P + S S PP L+
Sbjct: 700 ----PPPEDSPASPPPEDSLM 716
Score = 42.0 bits (97), Expect = 0.003
Identities = 93/412 (22%), Positives = 150/412 (36%), Gaps = 77/412 (18%)
Query: 263 TVTSSKISQRDPSPESNKKGESP----SLESRSTAVTRTSSIHQLIAPASYSPIQPHSLI 318
++ S S+ SP+S +SP L + + + + Q P S P +P S
Sbjct: 2402 SLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS-- 2459
Query: 319 KHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDPPPSQHCIPL----QNHGLPP 374
+ PLH PP Q + + +L +++ +P + H P
Sbjct: 2460 RDPFAPLHKPPRP--------QPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511
Query: 375 A---PSNAQSQHCSPIQSHPSPLTVSPNQS--QSAQQSVVVSP--PPPHSPSQ------- 420
+ P+ +S PSP+ + Q+ + + + V P PPPH +
Sbjct: 2512 SGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPT 2571
Query: 421 --SPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPAS----P 474
P + A HP S GP+ + + + L PS LP PA P
Sbjct: 2572 LGKPQSTNYTVATGNFHP---SGSPLGPS--SGSTGESYGLSPLRPPSVLPPPAPDGSLP 2626
Query: 475 VVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQ 534
+ G Q+S + SP ++ P SSL ++ +P P MS + L+ +
Sbjct: 2627 YLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMS-----GLSQTELEKQR 2681
Query: 535 SLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLP------------FQTLPPPQTVAV 582
Q E+L + Q+ +N L E+E AA A P F+ L QT
Sbjct: 2682 QRQRLRELLIRQQI-QRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFA 2740
Query: 583 NLQVQ------PPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLS 628
Q + PP+ + P++ P R+ R PPP T S
Sbjct: 2741 GTQDKSSLVGLPPSKLSGPIL----------GPGSFPSDDRLSRPPPPATPS 2782
Score = 31.6 bits (70), Expect = 3.9
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 9/86 (10%)
Query: 358 PPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPNQSQSAQQSVVV------- 410
PPP + C L LP P + S SPLT P +++ S V
Sbjct: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPD 2448
Query: 411 --SPPPPHSPSQSPTIIIHPQALIQP 434
S PP S+ P +H QP
Sbjct: 2449 PYSRPPSRPQSRDPFAPLHKPPRPQP 2474
Score = 31.6 bits (70), Expect = 3.9
Identities = 31/129 (24%), Positives = 49/129 (37%), Gaps = 3/129 (2%)
Query: 130 QQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTM---LLGSTSPTLTASQAQMY 186
QQ Q +L ++P PAQ +S SS S + +QQ + L G+ P L
Sbjct: 3274 QQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQ 3333
Query: 187 LRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPP 246
A L A ++A V + ++S Q L + +G + S P
Sbjct: 3334 PPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKP 3393
Query: 247 KSTSQTQSL 255
+ + Q L
Sbjct: 3394 QQLAMQQQL 3402
Score = 31.2 bits (69), Expect = 5.1
Identities = 42/164 (25%), Positives = 58/164 (35%), Gaps = 23/164 (14%)
Query: 561 PAAEALVQLPFQTLPPPQTVAVNLQVQPP--APVDPPVVYQVEDVCEEEMP--------- 609
P EA + LPPP+ ++ PP +P PP EE+P
Sbjct: 428 PQLEAPLNEEMPLLPPPEESPLS---PPPEESPTSPPPEASRLSPPPEELPASPLPEALH 484
Query: 610 -----EESDECVRMDRTP--PPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASV 662
EES + +P PPP SP + E P +E P AS
Sbjct: 485 LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASP 544
Query: 663 IKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQ 706
+ P + S +S PPP LP + S S + PP+
Sbjct: 545 LSPPFEESPLS--PPPEELPTSPPPEASRLSPPPEESPMSPPPE 586
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.123 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,853,547
Number of Sequences: 37866
Number of extensions: 2459379
Number of successful extensions: 23719
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 158
Number of HSP's successfully gapped in prelim test: 1290
Number of HSP's that attempted gapping in prelim test: 13393
Number of HSP's gapped (non-prelim): 7186
length of query: 995
length of database: 18,247,518
effective HSP length: 112
effective length of query: 883
effective length of database: 14,006,526
effective search space: 12367762458
effective search space used: 12367762458
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.