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Search of human proteins with 148612859
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148612859 coiled-coil-helix-coiled-coil-helix domain
containing 4 isoform 1 [Homo sapiens]
(142 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148612859 coiled-coil-helix-coiled-coil-helix domain containi... 304 2e-83
gi|21389469 coiled-coil-helix-coiled-coil-helix domain containin... 291 1e-79
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 36 0.009
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 36 0.009
gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens] 36 0.009
gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens] 36 0.009
gi|118600967 shroom family member 4 [Homo sapiens] 35 0.016
gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo sap... 35 0.016
gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo sap... 35 0.016
gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo sap... 35 0.016
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens] 35 0.027
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 33 0.061
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 33 0.061
gi|17975763 myelin transcription factor 1 [Homo sapiens] 33 0.079
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 33 0.10
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 33 0.10
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 32 0.14
gi|28274705 family with sequence similarity 9, member A [Homo sa... 32 0.14
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ... 32 0.18
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 32 0.18
gi|4504487 histidine rich calcium binding protein precursor [Hom... 32 0.23
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 32 0.23
gi|197100900 iroquois homeobox 2 [Homo sapiens] 32 0.23
gi|39930475 iroquois homeobox 2 [Homo sapiens] 32 0.23
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 32 0.23
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 31 0.30
gi|118918435 von Willebrand factor A domain containing 3B [Homo ... 31 0.30
gi|116235474 LKB1 interacting protein [Homo sapiens] 31 0.30
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 31 0.39
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens] 31 0.39
>gi|148612859 coiled-coil-helix-coiled-coil-helix domain containing
4 isoform 1 [Homo sapiens]
Length = 142
Score = 304 bits (778), Expect = 2e-83
Identities = 142/142 (100%), Positives = 142/142 (100%)
Query: 1 MSYCRQEGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGNINWNCPCLGGMA 60
MSYCRQEGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGNINWNCPCLGGMA
Sbjct: 1 MSYCRQEGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGNINWNCPCLGGMA 60
Query: 61 SGPCGEQFKSAFSCFHYSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKP 120
SGPCGEQFKSAFSCFHYSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKP
Sbjct: 61 SGPCGEQFKSAFSCFHYSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKP 120
Query: 121 AEQAEETAPIEATATKEEEGSS 142
AEQAEETAPIEATATKEEEGSS
Sbjct: 121 AEQAEETAPIEATATKEEEGSS 142
>gi|21389469 coiled-coil-helix-coiled-coil-helix domain containing 4
isoform 2 [Homo sapiens]
Length = 155
Score = 291 bits (745), Expect = 1e-79
Identities = 136/137 (99%), Positives = 137/137 (100%)
Query: 6 QEGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGNINWNCPCLGGMASGPCG 65
+EGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGNINWNCPCLGGMASGPCG
Sbjct: 19 EEGKDRIIFVTKEDHETPSSAELVADDPNDPYEEHGLILPNGNINWNCPCLGGMASGPCG 78
Query: 66 EQFKSAFSCFHYSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAE 125
EQFKSAFSCFHYSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAE
Sbjct: 79 EQFKSAFSCFHYSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAE 138
Query: 126 ETAPIEATATKEEEGSS 142
ETAPIEATATKEEEGSS
Sbjct: 139 ETAPIEATATKEEEGSS 155
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 36.2 bits (82), Expect = 0.009
Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 72 FSCFH--YSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAP 129
FS ++ YS +E SD + A+ E + + +E+E+EEEE E++ E+ EE
Sbjct: 270 FSLYYDSYSVDERVDSDSKSEVEALTEQLSE-----EEEEEEEEEEEEEEEEEEEEEEED 324
Query: 130 IEATATKEEEGSS 142
E+ + GSS
Sbjct: 325 EESGNQSDRSGSS 337
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 36.2 bits (82), Expect = 0.009
Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 7/73 (9%)
Query: 72 FSCFH--YSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAP 129
FS ++ YS +E SD + A+ E + + +E+E+EEEE E++ E+ EE
Sbjct: 270 FSLYYDSYSVDERVDSDSKSEVEALTEQLSE-----EEEEEEEEEEEEEEEEEEEEEEED 324
Query: 130 IEATATKEEEGSS 142
E+ + GSS
Sbjct: 325 EESGNQSDRSGSS 337
>gi|57242757 calsyntenin 1 isoform 1 [Homo sapiens]
Length = 981
Score = 36.2 bits (82), Expect = 0.009
Identities = 16/44 (36%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Query: 98 MQKYPDLYP-QEDEDEEEEREKKPAEQAEETAPIEATATKEEEG 140
M+ Y D + +E+E+EEEE E + E+ ++ E+ +++EEEG
Sbjct: 915 METYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEG 958
>gi|57242755 calsyntenin 1 isoform 2 [Homo sapiens]
Length = 971
Score = 36.2 bits (82), Expect = 0.009
Identities = 16/44 (36%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Query: 98 MQKYPDLYP-QEDEDEEEEREKKPAEQAEETAPIEATATKEEEG 140
M+ Y D + +E+E+EEEE E + E+ ++ E+ +++EEEG
Sbjct: 905 METYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEG 948
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 35.4 bits (80), Expect = 0.016
Identities = 18/41 (43%), Positives = 25/41 (60%)
Query: 91 FRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIE 131
FRA Q+ Q+ QE+E+EEEE E++ E+ EE A E
Sbjct: 1115 FRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEE 1155
Score = 32.0 bits (71), Expect = 0.18
Identities = 15/40 (37%), Positives = 25/40 (62%)
Query: 90 QFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAP 129
Q + Q+ Q+ + +E+E+EEEE E++ AE+ EE P
Sbjct: 1121 QKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELP 1160
Score = 29.6 bits (65), Expect = 0.88
Identities = 13/35 (37%), Positives = 22/35 (62%)
Query: 95 QECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAP 129
Q+ Q+ + +E+E+EEEE E++ E+ EE P
Sbjct: 1127 QQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPP 1161
Score = 29.3 bits (64), Expect = 1.1
Identities = 14/37 (37%), Positives = 22/37 (59%)
Query: 90 QFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEE 126
Q + Q+ QK + +E+E+EEEE E++ E EE
Sbjct: 1119 QQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEE 1155
>gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo
sapiens]
Length = 594
Score = 35.4 bits (80), Expect = 0.016
Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 90 QFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIE 131
Q E +Q Y D +EDEDEEEE E+K AE+ +E E
Sbjct: 245 QVNLRDELLQLYSDS-DEEDEDEEEEEEEKEAEEEQEEEEAE 285
>gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo
sapiens]
Length = 602
Score = 35.4 bits (80), Expect = 0.016
Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 90 QFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIE 131
Q E +Q Y D +EDEDEEEE E+K AE+ +E E
Sbjct: 253 QVNLRDELLQLYSDS-DEEDEDEEEEEEEKEAEEEQEEEEAE 293
>gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo
sapiens]
Length = 619
Score = 35.4 bits (80), Expect = 0.016
Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 90 QFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIE 131
Q E +Q Y D +EDEDEEEE E+K AE+ +E E
Sbjct: 245 QVNLRDELLQLYSDS-DEEDEDEEEEEEEKEAEEEQEEEEAE 285
>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
Length = 543
Score = 34.7 bits (78), Expect = 0.027
Identities = 18/64 (28%), Positives = 35/64 (54%)
Query: 76 HYSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIEATAT 135
H E+I+ + ++ +A + + + +E+E ++EE E++ A + EE A E+
Sbjct: 446 HVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEA 505
Query: 136 KEEE 139
KEEE
Sbjct: 506 KEEE 509
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 33.5 bits (75), Expect = 0.061
Identities = 17/41 (41%), Positives = 23/41 (56%)
Query: 102 PDLYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEEGSS 142
P+ P E + E +E E KPA +T P +AT TKE E +
Sbjct: 808 PEKGPVEAKPECQETETKPAPAEVKTVPNDATQTKENESKA 848
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 33.5 bits (75), Expect = 0.061
Identities = 17/41 (41%), Positives = 23/41 (56%)
Query: 102 PDLYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEEGSS 142
P+ P E + E +E E KPA +T P +AT TKE E +
Sbjct: 818 PEKGPVEAKPECQETETKPAPAEVKTVPNDATQTKENESKA 858
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 33.1 bits (74), Expect = 0.079
Identities = 18/47 (38%), Positives = 24/47 (51%)
Query: 93 AMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
A E K + E+EDEEEE E++ E+ EE E +EEE
Sbjct: 243 AASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE 289
Score = 32.3 bits (72), Expect = 0.14
Identities = 15/33 (45%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+EDEEEE E++ E+ EE E +EEE
Sbjct: 270 EEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302
Score = 32.3 bits (72), Expect = 0.14
Identities = 15/33 (45%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+EDE+EEEE E++ E+ EE E +EEE
Sbjct: 272 EEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
Score = 31.6 bits (70), Expect = 0.23
Identities = 14/35 (40%), Positives = 22/35 (62%)
Query: 105 YPQEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+ +EDE+EEEE E++ ++ EE E +EEE
Sbjct: 257 HEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291
Score = 30.8 bits (68), Expect = 0.39
Identities = 16/54 (29%), Positives = 28/54 (51%)
Query: 86 DCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
D + + Q+ + + + +E+E+EEEE E + E+ EE E +EEE
Sbjct: 242 DAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEE 295
Score = 30.8 bits (68), Expect = 0.39
Identities = 12/23 (52%), Positives = 18/23 (78%)
Query: 107 QEDEDEEEEREKKPAEQAEETAP 129
+E+E+EEEE E++ E+ EE AP
Sbjct: 287 EEEEEEEEEEEEEEEEEEEEAAP 309
Score = 30.4 bits (67), Expect = 0.52
Identities = 14/34 (41%), Positives = 21/34 (61%)
Query: 108 EDEDEEEEREKKPAEQAEETAPIEATATKEEEGS 141
E+E+EEEE E++ E+ EE E +EEE +
Sbjct: 275 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
Score = 30.0 bits (66), Expect = 0.67
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E+EEEE E++ E+ EE E +EEE
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
Score = 29.6 bits (65), Expect = 0.88
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E+EEEE +++ E+ EE E +EEE
Sbjct: 264 EEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296
Score = 29.6 bits (65), Expect = 0.88
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E+EEE+ E++ E+ EE E +EEE
Sbjct: 266 EEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298
Score = 29.6 bits (65), Expect = 0.88
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E+EE+E E++ E+ EE E +EEE
Sbjct: 267 EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299
Score = 29.6 bits (65), Expect = 0.88
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E+E+EE E++ E+ EE E +EEE
Sbjct: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
Score = 29.6 bits (65), Expect = 0.88
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E++EEE E++ E+ EE E +EEE
Sbjct: 269 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEE 301
Score = 29.6 bits (65), Expect = 0.88
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+++EEEE E++ E+ EE E +EEE
Sbjct: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
Score = 29.6 bits (65), Expect = 0.88
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+++E+EEEE E++ E+ EE E +EEE
Sbjct: 273 EDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Score = 28.9 bits (63), Expect = 1.5
Identities = 13/32 (40%), Positives = 20/32 (62%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEE 138
+E+E+EEEE E++ E+ EE E +EE
Sbjct: 275 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 27.7 bits (60), Expect = 3.3
Identities = 12/26 (46%), Positives = 18/26 (69%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEA 132
+E+E+EEEE E++ E+ EE EA
Sbjct: 282 EEEEEEEEEEEEEEEEEEEEEEEEEA 307
Score = 27.3 bits (59), Expect = 4.4
Identities = 12/31 (38%), Positives = 19/31 (61%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKE 137
+E+E+EEEE E++ E+ EE E A +
Sbjct: 280 EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 32.7 bits (73), Expect = 0.10
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 82 IKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
I G + V Q M E P+++ +E+E+E+EE E + ++ E+ E TA ++E+
Sbjct: 1853 IFGDEDVKQILKMIE-----PEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKED 1905
Score = 29.3 bits (64), Expect = 1.1
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E EEE+ E+K E EETA + KEEE
Sbjct: 1880 EEEEGEEEDEEEK-EEDEEETAQEKEDEEKEEE 1911
Score = 28.5 bits (62), Expect = 2.0
Identities = 15/36 (41%), Positives = 24/36 (66%), Gaps = 2/36 (5%)
Query: 107 QEDEDEEEEREKKPAEQA--EETAPIEATATKEEEG 140
+EDE+E+EE E++ A++ EE EA ++EEG
Sbjct: 1886 EEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEG 1921
Score = 28.5 bits (62), Expect = 2.0
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 81 EIKGSDCVDQFRAMQECMQ-KYPDLYPQEDEDEEEEREKKPAEQAEE-TAPIEATATKEE 138
E+ S C D MQ Q P+ P+ DEDE + AE AEE A +E TA
Sbjct: 4226 ELFVSFCEDTIFEMQIAAQISEPEGEPETDEDEGAGAAEAGAEGAEEGAAGLEGTAATAA 4285
Query: 139 EGSS 142
G++
Sbjct: 4286 AGAT 4289
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 32.7 bits (73), Expect = 0.10
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 5/58 (8%)
Query: 82 IKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
I G + V Q M E P+++ +E+E+E+EE E + ++ E+ E TA ++E+
Sbjct: 1853 IFGDEDVKQILKMIE-----PEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKED 1905
Score = 29.3 bits (64), Expect = 1.1
Identities = 16/33 (48%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E EEE+ E+K E EETA + KEEE
Sbjct: 1880 EEEEGEEEDEEEK-EEDEEETAQEKEDEEKEEE 1911
Score = 28.5 bits (62), Expect = 2.0
Identities = 15/36 (41%), Positives = 24/36 (66%), Gaps = 2/36 (5%)
Query: 107 QEDEDEEEEREKKPAEQA--EETAPIEATATKEEEG 140
+EDE+E+EE E++ A++ EE EA ++EEG
Sbjct: 1886 EEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEG 1921
Score = 28.5 bits (62), Expect = 2.0
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 81 EIKGSDCVDQFRAMQECMQ-KYPDLYPQEDEDEEEEREKKPAEQAEE-TAPIEATATKEE 138
E+ S C D MQ Q P+ P+ DEDE + AE AEE A +E TA
Sbjct: 4231 ELFVSFCEDTIFEMQIAAQISEPEGEPETDEDEGAGAAEAGAEGAEEGAAGLEGTAATAA 4290
Query: 139 EGSS 142
G++
Sbjct: 4291 AGAT 4294
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 32.3 bits (72), Expect = 0.14
Identities = 15/36 (41%), Positives = 23/36 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEEGSS 142
+EDE+EEEE E++ E+ EE E +EEE ++
Sbjct: 739 EEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAA 774
Score = 31.6 bits (70), Expect = 0.23
Identities = 15/33 (45%), Positives = 20/33 (60%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+EDEEEE E + E+ EE E +EEE
Sbjct: 737 EEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769
Score = 29.6 bits (65), Expect = 0.88
Identities = 15/38 (39%), Positives = 21/38 (55%)
Query: 102 PDLYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
P +E+E+EEEE E++ E EE E +EEE
Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEE 764
Score = 29.6 bits (65), Expect = 0.88
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E+E+EE E++ E+ EE E +EEE
Sbjct: 735 EEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEE 767
Score = 29.3 bits (64), Expect = 1.1
Identities = 13/33 (39%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E+EE+E E++ E+ EE E +EEE
Sbjct: 734 EEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEE 766
Score = 28.9 bits (63), Expect = 1.5
Identities = 13/33 (39%), Positives = 20/33 (60%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E++EEE E+ E+ EE E +EEE
Sbjct: 736 EEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEE 768
Score = 28.9 bits (63), Expect = 1.5
Identities = 14/34 (41%), Positives = 20/34 (58%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEEG 140
+E+E+EEEE E++ E+ EE A A E G
Sbjct: 750 EEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLG 783
Score = 28.5 bits (62), Expect = 2.0
Identities = 12/33 (36%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+E+EEE+ E++ ++ EE E +EEE
Sbjct: 733 EEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEE 765
Score = 28.5 bits (62), Expect = 2.0
Identities = 12/33 (36%), Positives = 21/33 (63%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+E+++EEEE +++ E+ EE E +EEE
Sbjct: 738 EEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 770
Score = 26.9 bits (58), Expect = 5.7
Identities = 11/36 (30%), Positives = 22/36 (61%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEEGSS 142
+++E+EEE+ E++ E+ EE E +EE ++
Sbjct: 740 EDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAA 775
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 32.3 bits (72), Expect = 0.14
Identities = 18/61 (29%), Positives = 29/61 (47%)
Query: 80 EEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
EE + + + A E ++ EDE+EEE+ E++ E+ EE E + EE
Sbjct: 192 EEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEE 251
Query: 140 G 140
G
Sbjct: 252 G 252
>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
sapiens]
Length = 4621
Score = 32.0 bits (71), Expect = 0.18
Identities = 21/65 (32%), Positives = 37/65 (56%), Gaps = 8/65 (12%)
Query: 80 EEIKGSDCVDQF----RAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEE-TAPIEATA 134
++ +G D +Q R Q +QK L P+ DEDE+E+ + + AE+ ++ +AP E
Sbjct: 137 DKSQGQDLQEQLAEGCRLAQHLVQK---LSPENDEDEDEDVQVEEAEKVQKSSAPREVQK 193
Query: 135 TKEEE 139
T+E +
Sbjct: 194 TEESK 198
Score = 27.7 bits (60), Expect = 3.3
Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 8/65 (12%)
Query: 80 EEIKGSDCVDQF----RAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEE-TAPIEATA 134
++ +G D +Q R Q +QK L P+ D D++E+ + + AE+ ++ +AP E
Sbjct: 408 DKSQGQDLQEQLAEGCRLAQHLVQK---LSPENDNDDDEDVQVELAEKVQKSSAPREMQK 464
Query: 135 TKEEE 139
+E+E
Sbjct: 465 AEEKE 469
>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
Length = 224
Score = 32.0 bits (71), Expect = 0.18
Identities = 14/32 (43%), Positives = 20/32 (62%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEE 138
+E+E+EEEE E++ E+ EE AP EE
Sbjct: 48 EEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEE 79
Score = 28.1 bits (61), Expect = 2.6
Identities = 12/29 (41%), Positives = 18/29 (62%)
Query: 106 PQEDEDEEEEREKKPAEQAEETAPIEATA 134
P +DE++EEE E++ E+ EE E A
Sbjct: 41 PDDDEEDEEEEEEEEEEEEEEEEEEEEEA 69
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 31.6 bits (70), Expect = 0.23
Identities = 14/32 (43%), Positives = 23/32 (71%)
Query: 108 EDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
++E+EEEE E++ E+AE AP+ ++EEE
Sbjct: 540 KEEEEEEEDEERREERAEVGAPLSPDHSEEEE 571
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 31.6 bits (70), Expect = 0.23
Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 93 AMQECMQKYPDLYPQ---EDEDEEEEREKKPAEQAEETAPIEATATKEEEGSS 142
+M+E +Q+Y Y EDE+E+ + E P+EA +E+ SS
Sbjct: 443 SMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSS 495
Score = 26.6 bits (57), Expect = 7.4
Identities = 11/23 (47%), Positives = 15/23 (65%)
Query: 103 DLYPQEDEDEEEEREKKPAEQAE 125
D PQEDE+E++E + EQ E
Sbjct: 288 DFQPQEDEEEDDEETIEVEEQQE 310
>gi|197100900 iroquois homeobox 2 [Homo sapiens]
Length = 471
Score = 31.6 bits (70), Expect = 0.23
Identities = 14/25 (56%), Positives = 15/25 (60%)
Query: 96 ECMQKYPDLYPQEDEDEEEEREKKP 120
EC KY DL ED+DEE ER P
Sbjct: 255 ECKDKYDDLEDDEDDDEEGERGLAP 279
>gi|39930475 iroquois homeobox 2 [Homo sapiens]
Length = 471
Score = 31.6 bits (70), Expect = 0.23
Identities = 14/25 (56%), Positives = 15/25 (60%)
Query: 96 ECMQKYPDLYPQEDEDEEEEREKKP 120
EC KY DL ED+DEE ER P
Sbjct: 255 ECKDKYDDLEDDEDDDEEGERGLAP 279
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 31.6 bits (70), Expect = 0.23
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 95 QECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEEGSS 142
+E M+K ++ +E+++EEEE E K E+ E E EEEG S
Sbjct: 378 EEEMKKEEEMKKKEEKEEEEEEEMKQKEEEE-----EIRNKNEEEGES 420
Score = 26.9 bits (58), Expect = 5.7
Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 3/51 (5%)
Query: 89 DQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
DQ + M+ Q+ + +E+E+ ++E E K E+ EE E +EEE
Sbjct: 361 DQRKRMRAFQQEMKE---KEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEE 408
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 31.2 bits (69), Expect = 0.30
Identities = 15/33 (45%), Positives = 20/33 (60%)
Query: 107 QEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
+EDEDE+EE ++ AE ET A +EEE
Sbjct: 28 REDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
Score = 26.9 bits (58), Expect = 5.7
Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Query: 85 SDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQ-AEETAPIEATATKEEE 139
SD + +E Q+ + +ED E+E+ +++ AE+ AE A E T +E+E
Sbjct: 2 SDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDE 57
>gi|118918435 von Willebrand factor A domain containing 3B [Homo
sapiens]
Length = 1294
Score = 31.2 bits (69), Expect = 0.30
Identities = 19/76 (25%), Positives = 29/76 (38%)
Query: 67 QFKSAFSCFHYSTEEIKGSDCVDQFRAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEE 126
Q K A SC H + I V+ A +P + E REK ++
Sbjct: 1153 QNKYALSCSHIKSPPIPEDPEVEDVEARNSAFLFWPLKEADTQDSREPRREKPRRKKRPA 1212
Query: 127 TAPIEATATKEEEGSS 142
P++ A + +GSS
Sbjct: 1213 KQPLQQAAPSDSDGSS 1228
>gi|116235474 LKB1 interacting protein [Homo sapiens]
Length = 1099
Score = 31.2 bits (69), Expect = 0.30
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 3/54 (5%)
Query: 89 DQFRAMQECMQKYPD---LYPQEDEDEEEEREKKPAEQAEETAPIEATATKEEE 139
++ R QE QK + PQE+E+E+E +E+K + E EA +EEE
Sbjct: 485 EEARGPQESPQKMSEEVRAEPQEEEEEKEGKEEKEEGEMVEQGEEEAGEEEEEE 538
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 30.8 bits (68), Expect = 0.39
Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 3/51 (5%)
Query: 83 KGSDCVDQFRAMQECMQKYP---DLYPQEDEDEEEEREKKPAEQAEETAPI 130
+G++ V + + ++K P +E EDEEEE E++ E+ EE +
Sbjct: 325 QGTEVVPAYEEENKAVEKMPRELSRIEEEKEDEEEEEEEEEEEEEEEVTEV 375
Score = 26.2 bits (56), Expect = 9.7
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 7/42 (16%)
Query: 104 LYPQEDEDEEEEREKKPAEQAEETAPIEA-------TATKEE 138
L+ + E+ ++E E+K E+AEE A EA TKEE
Sbjct: 405 LWEEVGEEAKKEAEEKAKEEAEEVAEEEAEKEPQDWAETKEE 446
>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
Length = 3628
Score = 30.8 bits (68), Expect = 0.39
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 8/65 (12%)
Query: 80 EEIKGSDCVDQF----RAMQECMQKYPDLYPQEDEDEEEEREKKPAEQA-EETAPIEATA 134
++ +G D +Q R Q +QK L P+ DEDE+E+ + + AE+ E +AP E
Sbjct: 137 DKSQGQDLQEQLAEGCRLAQHLVQK---LSPENDEDEDEDVQVEEAEKVLESSAPREVQK 193
Query: 135 TKEEE 139
+E +
Sbjct: 194 AEESK 198
Score = 30.4 bits (67), Expect = 0.52
Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 8/68 (11%)
Query: 77 YSTEEIKGSDCVDQF----RAMQECMQKYPDLYPQEDEDEEEEREKKPAEQAEE-TAPIE 131
Y ++ +G D +Q R Q +QK L P+ D D++E+ + + AE+ ++ +AP E
Sbjct: 405 YEPDKSQGQDLQEQLAEGCRLAQHLVQK---LSPENDNDDDEDVQVEVAEKVQKSSAPRE 461
Query: 132 ATATKEEE 139
+E+E
Sbjct: 462 MQKAEEKE 469
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.130 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,717,327
Number of Sequences: 37866
Number of extensions: 335763
Number of successful extensions: 5869
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 261
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 3362
Number of HSP's gapped (non-prelim): 1679
length of query: 142
length of database: 18,247,518
effective HSP length: 92
effective length of query: 50
effective length of database: 14,763,846
effective search space: 738192300
effective search space used: 738192300
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.