Search of human proteins with 148612831

Search of human proteins with 148612831

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148612831 kinesin family member 18A [Homo sapiens]
         (898 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148612831 kinesin family member 18A [Homo sapiens]                1795   0.0  
gi|122937289 kinesin family member 18B [Homo sapiens]                 465   e-131
gi|156616271 kinesin family member 19 [Homo sapiens]                  327   4e-89
gi|4758646 kinesin family member 3B [Homo sapiens]                    264   3e-70
gi|46852174 kinesin family member 3A [Homo sapiens]                   261   2e-69
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]     241   2e-63
gi|41393563 kinesin family member 1B isoform b [Homo sapiens]         241   2e-63
gi|116686122 kinesin family member 4 [Homo sapiens]                   241   2e-63
gi|46852172 kinesin family member 13B [Homo sapiens]                  239   6e-63
gi|150010604 kinesin family member 4B [Homo sapiens]                  239   8e-63
gi|41352705 kinesin family member 3C [Homo sapiens]                   239   1e-62
gi|30794488 kinesin family member 27 [Homo sapiens]                   237   3e-62
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]      234   2e-61
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]        234   4e-61
gi|83716024 kinesin family member 21B [Homo sapiens]                  233   5e-61
gi|157738629 kinesin family member 13A isoform d [Homo sapiens]       233   6e-61
gi|157738627 kinesin family member 13A isoform c [Homo sapiens]       233   6e-61
gi|157738625 kinesin family member 13A isoform b [Homo sapiens]       233   6e-61
gi|157738621 kinesin family member 13A isoform a [Homo sapiens]       233   6e-61
gi|170784809 kinesin family member 17 isoform b [Homo sapiens]        233   6e-61
gi|170784807 kinesin family member 17 isoform a [Homo sapiens]        233   6e-61
gi|203096856 kinesin family member 7 [Homo sapiens]                   232   1e-60
gi|38569484 kinesin family member 21A [Homo sapiens]                  231   2e-60
gi|13699824 kinesin family member 11 [Homo sapiens]                   231   2e-60
gi|40254834 kinesin family member 1C [Homo sapiens]                   227   3e-59
gi|71061468 centromere protein E [Homo sapiens]                       222   1e-57
gi|4758650 kinesin family member 5C [Homo sapiens]                    221   2e-57
gi|9910266 kinesin family member 15 [Homo sapiens]                    220   4e-57
gi|45446749 kinesin family member 5A [Homo sapiens]                   218   2e-56
gi|4758648 kinesin family member 5B [Homo sapiens]                    216   1e-55

>gi|148612831 kinesin family member 18A [Homo sapiens]
          Length = 898

 Score = 1795 bits (4649), Expect = 0.0
 Identities = 898/898 (100%), Positives = 898/898 (100%)

Query: 1   MSVTEEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTT 60
           MSVTEEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTT
Sbjct: 1   MSVTEEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTT 60

Query: 61  NQNVIKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKT 120
           NQNVIKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKT
Sbjct: 61  NQNVIKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKT 120

Query: 121 HTMLGSADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVR 180
           HTMLGSADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVR
Sbjct: 121 HTMLGSADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVR 180

Query: 181 EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD 240
           EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD
Sbjct: 181 EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD 240

Query: 241 KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR 300
           KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR
Sbjct: 241 KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR 300

Query: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360
           KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK
Sbjct: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360

Query: 361 SNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQEKEIE 420
           SNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQEKEIE
Sbjct: 361 SNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQEKEIE 420

Query: 421 RFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKR 480
           RFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKR
Sbjct: 421 RFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKR 480

Query: 481 DHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHH 540
           DHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHH
Sbjct: 481 DHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHH 540

Query: 541 LHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESD 600
           LHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESD
Sbjct: 541 LHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESD 600

Query: 601 FKEIEHLVERKKVVVWADQTAEQPKQNDLPGISVLMTFPQLGPVQPIPCCSSSGGTNLVK 660
           FKEIEHLVERKKVVVWADQTAEQPKQNDLPGISVLMTFPQLGPVQPIPCCSSSGGTNLVK
Sbjct: 601 FKEIEHLVERKKVVVWADQTAEQPKQNDLPGISVLMTFPQLGPVQPIPCCSSSGGTNLVK 660

Query: 661 IPTEKRTRRKLMPSPLKGQHTLKSPPSQSVQLNDSLSKELQPIVYTPEDCRKAFQNPSTV 720
           IPTEKRTRRKLMPSPLKGQHTLKSPPSQSVQLNDSLSKELQPIVYTPEDCRKAFQNPSTV
Sbjct: 661 IPTEKRTRRKLMPSPLKGQHTLKSPPSQSVQLNDSLSKELQPIVYTPEDCRKAFQNPSTV 720

Query: 721 TLMKPSSFTTSFQAISSNINSDNCLKMLCEVAIPHNRRKECGQEDLDSTFTICEDIKSSK 780
           TLMKPSSFTTSFQAISSNINSDNCLKMLCEVAIPHNRRKECGQEDLDSTFTICEDIKSSK
Sbjct: 721 TLMKPSSFTTSFQAISSNINSDNCLKMLCEVAIPHNRRKECGQEDLDSTFTICEDIKSSK 780

Query: 781 CKLPEQESLPNDNKDILQRLDPSSFSTKHSMPVPSMVPSYMAMTTAAKRKRKLTSSTSNS 840
           CKLPEQESLPNDNKDILQRLDPSSFSTKHSMPVPSMVPSYMAMTTAAKRKRKLTSSTSNS
Sbjct: 781 CKLPEQESLPNDNKDILQRLDPSSFSTKHSMPVPSMVPSYMAMTTAAKRKRKLTSSTSNS 840

Query: 841 SLTADVNSGFAKRVRQDNSSEKHLQENKPTMEHKRNICKINPSMVRKFGRNISKGNLR 898
           SLTADVNSGFAKRVRQDNSSEKHLQENKPTMEHKRNICKINPSMVRKFGRNISKGNLR
Sbjct: 841 SLTADVNSGFAKRVRQDNSSEKHLQENKPTMEHKRNICKINPSMVRKFGRNISKGNLR 898


>gi|122937289 kinesin family member 18B [Homo sapiens]
          Length = 855

 Score =  465 bits (1197), Expect = e-131
 Identities = 231/384 (60%), Positives = 297/384 (77%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           ++VVVRVRP   +E  +    VV VVD+ +LVF+P++ +  F   K     +  KK+ KD
Sbjct: 8   LQVVVRVRPPTPRELDSQRRPVVQVVDERVLVFNPEEPDGGFPGLKWGGTHDGPKKKGKD 67

Query: 72  LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPG 131
           L FVFD VF E +TQ +VF+HTT  +L SFL GYNC+V AYGATGAGKTHTMLG   +PG
Sbjct: 68  LTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLGREGDPG 127

Query: 132 VMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLAVREDTQKGVVVHG 191
           +MYLT + LY+ ++  ++EK     +SY EVYNEQI DLL   GPLA+RED  KGVVV G
Sbjct: 128 IMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLLEPKGPLAIREDPDKGVVVQG 187

Query: 192 LTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASINQNVRI 251
           L+ HQP S+E++L +L  GN+NRTQHPTD NATSSRSHA+FQI+++QQD+   + Q V++
Sbjct: 188 LSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIFVKQQDRVPGLTQAVQV 247

Query: 252 AKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSK 311
           AKMSLIDLAGSERAS++ AKG R  EG NINRSLLAL NV+NALAD+K +  H+PYR+SK
Sbjct: 248 AKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKGRKTHVPYRDSK 307

Query: 312 LTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHIT 371
           LTRLLKDSLGGNC+T+MIAA+SPSS+ Y+DTYNTLKYA+RAK+I+ SLKSNV +++ HI+
Sbjct: 308 LTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAKEIRLSLKSNVTSLDCHIS 367

Query: 372 QYVKICNEQKAEILLLKEKLKAYE 395
           QY  IC + +AE+  L++KL+ YE
Sbjct: 368 QYATICQQLQAEVAALRKKLQVYE 391


>gi|156616271 kinesin family member 19 [Homo sapiens]
          Length = 998

 Score =  327 bits (837), Expect = 4e-89
 Identities = 188/444 (42%), Positives = 279/444 (62%), Gaps = 22/444 (4%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVF-DPKQEEVSFFHGKKTTNQNVIKKQNK 70
           + V +RVRP +  E   G   + H VD+ ++V  DP ++        ++          +
Sbjct: 12  LMVALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRS----------R 61

Query: 71  DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP 130
           +  ++FD  FD T+TQ  V++ TTK ++   ++GYN TV AYG TG GKT+TMLG+  EP
Sbjct: 62  EKSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDQEP 121

Query: 131 GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNS-GPLAVREDTQKGVVV 189
           G+   T+  L++ ++E   +     ++SYLE+YNE IRDLL  S G L +RED++  + V
Sbjct: 122 GIYVQTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSLGYLELREDSKGVIQV 181

Query: 190 HGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASINQNV 249
            G+T     +++EI+ LL  GN+ RTQ PT  N TSSRSHAV Q+ +RQ+ +  +I Q V
Sbjct: 182 AGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEV 241

Query: 250 RIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRN 309
           R  ++ +IDLAGSERAS +  +G R  EG +INRSLLALGN INAL+D K  N++I YR+
Sbjct: 242 RQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSD-KGSNKYINYRD 300

Query: 310 SKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNH 369
           SKLTRLLKDSLGGN +T+MIA +SP+S  ++++ NTL YA RAK+IK+ +K N+LNV+ H
Sbjct: 301 SKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNLLNVSYH 360

Query: 370 ITQYVKICNEQKAEILLLKEKL-------KAYEEQKAFTNENDQAKLMISNPQEKE--IE 420
           I QY  I  + + EI  LK K+       +A   Q      + QA++ + + Q ++  + 
Sbjct: 361 IAQYTSIIADLRGEIQRLKRKIDEQTGRGQARGRQDRGDIRHIQAEVQLHSGQGEKAGMG 420

Query: 421 RFQEILNCLFQNREEIRQEYLKLE 444
           + +E L   FQ + ++R+  L+LE
Sbjct: 421 QLREQLASAFQEQMDVRRRLLELE 444


>gi|4758646 kinesin family member 3B [Homo sapiens]
          Length = 747

 Score =  264 bits (674), Expect = 3e-70
 Identities = 205/595 (34%), Positives = 318/595 (53%), Gaps = 67/595 (11%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           ++VVVR RP N KEKAA + KVV V        D K  +VS  + K T ++         
Sbjct: 10  VRVVVRCRPMNGKEKAASYDKVVDV--------DVKLGQVSVKNPKGTAHE-------MP 54

Query: 72  LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP- 130
             F FDAV+D  + Q E+++ T +P++ S L G+N T+ AYG TG GKT+TM G   +P 
Sbjct: 55  KTFTFDAVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPE 114

Query: 131 --GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP--LAVREDTQKG 186
             GV+  +  H++  +   + ++    A SYLE+Y E+IRDLL       L ++E    G
Sbjct: 115 KRGVIPNSFDHIFTHISRSQNQQYLVRA-SYLEIYQEEIRDLLSKDQTKRLELKERPDTG 173

Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
           V V  L+    KS +EI H+++ GN+NR+   T+MN  SSRSHA+F I +   +      
Sbjct: 174 VYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGE 233

Query: 247 QNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIP 306
            ++R+ K++L+DLAGSER + +GA+G R  E T IN SL ALGNVI+AL D   K+ HIP
Sbjct: 234 NHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDG--KSTHIP 291

Query: 307 YRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNV 366
           YR+SKLTRLL+DSLGGN +T+M+A V P+S   ++T  TL+YANRAK+IK+  + N    
Sbjct: 292 YRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNEDPK 351

Query: 367 NNHITQYVKICNEQKAEI-------LLLKEKLK-----------AYEEQKAFTNENDQAK 408
           +  + ++ +     KA++          +EK +             EE +    E D   
Sbjct: 352 DALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKD 411

Query: 409 LMISNPQEK-EIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMM 467
                 QEK EIE+       + ++   + +E ++   LLKE E K    ++     EM+
Sbjct: 412 DYWREQQEKLEIEK-----RAIVEDHSLVAEEKMR---LLKEKEKKMEDLRREKDAAEML 463

Query: 468 CSEDKVEKAT----GKR--DH---RLAMLKTRRSYL--EKRREEELKQFDENTNWLHRVE 516
            ++ K  ++     GK   DH   +  +L+ +R  +  +KRRE E++Q  E+     R E
Sbjct: 464 GAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMES-----RDE 518

Query: 517 KEMGLLSQNGHIPKELK-KDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTE 570
           + + L      + +E+  K      L  + + +KA+I  + +    + Q+  QT+
Sbjct: 519 ETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQ 573


>gi|46852174 kinesin family member 3A [Homo sapiens]
          Length = 699

 Score =  261 bits (667), Expect = 2e-69
 Identities = 200/612 (32%), Positives = 315/612 (51%), Gaps = 58/612 (9%)

Query: 9   CHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQ 68
           C ++KVVVR RP N +EK+  + + V V        D  +  ++     KT + N   K 
Sbjct: 12  CDNVKVVVRCRPLNEREKSMCYKQAVSV--------DEMRGTITVH---KTDSSNEPPKT 60

Query: 69  NKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSAD 128
                F FD VF   S Q +V+  T +PI+ S L GYN T+ AYG TG GKT TM G   
Sbjct: 61  -----FTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRA 115

Query: 129 EP---GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP--LAVREDT 183
            P   G++  +  H++  + + + +      VSYLE+YNE++RDLL       L V+E  
Sbjct: 116 IPELRGIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERP 175

Query: 184 QKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTA 243
             GV +  L+ +   +++++  ++  G+KNR+   T+MN  SSRSHA+F I +   +K  
Sbjct: 176 DVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGI 235

Query: 244 SINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQ 303
             N +VR+ K+ L+DLAGSER + +GA G R  E T IN SL  LGNVI+AL D   K+ 
Sbjct: 236 DGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDG--KST 293

Query: 304 HIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNV 363
           H+PYRNSKLTRLL+DSLGGN +T+M A + P+   YD+T +TL+YANRAK+IK+  + N 
Sbjct: 294 HVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINE 353

Query: 364 LNVNNHITQYVKICNEQKAEILLLKEKLKAYEE----QKAFTNENDQAKLMISNPQEKEI 419
              +  + Q+ K       EI  LK+KL+  EE      + + E+D  +  +    EK  
Sbjct: 354 DPKDALLRQFQK-------EIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRK 406

Query: 420 ERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGK 479
           +R         + ++++  + + +EM  K +E +   + +   + E     +K      K
Sbjct: 407 KR---------RGKKKVSPDKM-IEMQAKIDEERKALETKLDMEEE---ERNKARAELEK 453

Query: 480 RDHRLAML-KTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHC 538
           R+  L    +  +S LEK    E K      + L + E++  LL ++    +E +K    
Sbjct: 454 REKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQ 513

Query: 539 HHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFE 598
               L+ K+     +  +D+    E+++   +         L+K +  L  A    A  +
Sbjct: 514 LRRELEEKE-----QERLDI----EEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQ 564

Query: 599 SDF-KEIEHLVE 609
            +  +EIE L+E
Sbjct: 565 QEHQREIEGLLE 576


>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
          Length = 1153

 Score =  241 bits (616), Expect = 2e-63
 Identities = 173/479 (36%), Positives = 251/479 (52%), Gaps = 63/479 (13%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV VRVRP N++E +     ++ +      + +PK                  K+  K 
Sbjct: 6   VKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNP----------------KEAPKS 49

Query: 72  LKFVFDAVFDETS-------TQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTML 124
             F + + +  TS       +Q+ V+    K +L     GYN  + AYG TGAGK++TM+
Sbjct: 50  FSFDY-SYWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMM 108

Query: 125 GSADEP--GVMYLTMLHLY-KCMDEIKEEKICSTAVSYLEVYNEQIRDLL--VNSGPLAV 179
           G  +E   G++      L+ K  D   EE   S  VSY+E+Y E++RDLL   N G L V
Sbjct: 109 GKQEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRV 168

Query: 180 REDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQ 239
           RE    G  V  L+     S  +I  L+D GNK RT   T+MN TSSRSHAVF I   Q+
Sbjct: 169 REHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQK 228

Query: 240 DKTASINQNV-RIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD- 297
                 N +  +++K+SL+DLAGSERA ++GAKGTR  EG NIN+SL  LG VI+ALA+ 
Sbjct: 229 KHDNETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEV 288

Query: 298 --SKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDI 355
              K+K   IPYR+S LT LL+++LGGN +T M+AA+SP+ + YD+T +TL+YA+RAK I
Sbjct: 289 SKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQI 348

Query: 356 KSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKA---------------------- 393
           K +    V+N + +     K+  E K E+  LK+ L+A                      
Sbjct: 349 KCNA---VINEDPN----AKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCS 401

Query: 394 YEEQKAFTNEND-QAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENE 451
              Q   T+    Q ++M +   E+ IER +E    + +  E   ++  K E +  E E
Sbjct: 402 LSSQVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMERE 460


>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
          Length = 1770

 Score =  241 bits (616), Expect = 2e-63
 Identities = 173/479 (36%), Positives = 251/479 (52%), Gaps = 63/479 (13%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV VRVRP N++E +     ++ +      + +PK                  K+  K 
Sbjct: 6   VKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNP----------------KEAPKS 49

Query: 72  LKFVFDAVFDETS-------TQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTML 124
             F + + +  TS       +Q+ V+    K +L     GYN  + AYG TGAGK++TM+
Sbjct: 50  FSFDY-SYWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMM 108

Query: 125 GSADEP--GVMYLTMLHLY-KCMDEIKEEKICSTAVSYLEVYNEQIRDLL--VNSGPLAV 179
           G  +E   G++      L+ K  D   EE   S  VSY+E+Y E++RDLL   N G L V
Sbjct: 109 GKQEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRV 168

Query: 180 REDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQ 239
           RE    G  V  L+     S  +I  L+D GNK RT   T+MN TSSRSHAVF I   Q+
Sbjct: 169 REHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQK 228

Query: 240 DKTASINQNV-RIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD- 297
                 N +  +++K+SL+DLAGSERA ++GAKGTR  EG NIN+SL  LG VI+ALA+ 
Sbjct: 229 KHDNETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEV 288

Query: 298 --SKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDI 355
              K+K   IPYR+S LT LL+++LGGN +T M+AA+SP+ + YD+T +TL+YA+RAK I
Sbjct: 289 SKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQI 348

Query: 356 KSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKA---------------------- 393
           K +    V+N + +     K+  E K E+  LK+ L+A                      
Sbjct: 349 KCNA---VINEDPN----AKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCS 401

Query: 394 YEEQKAFTNEND-QAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENE 451
              Q   T+    Q ++M +   E+ IER +E    + +  E   ++  K E +  E E
Sbjct: 402 LSSQVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMERE 460


>gi|116686122 kinesin family member 4 [Homo sapiens]
          Length = 1232

 Score =  241 bits (616), Expect = 2e-63
 Identities = 169/437 (38%), Positives = 248/437 (56%), Gaps = 56/437 (12%)

Query: 71  DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGS---- 126
           D  F +D VFD ++ Q EVF     P+++    GYN TVLAYG TG+GKT++M G+    
Sbjct: 46  DKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAE 105

Query: 127 -ADEP--GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLA---VR 180
             +EP  GV+   +  L+K +D+ K +   +  VSYLE+YNE+I DLL  S   A   +R
Sbjct: 106 QENEPTVGVIPRVIQLLFKEIDK-KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIR 164

Query: 181 EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD 240
           ED ++G+ + GLT      + + +  L+ GN +RT   T MN+ SSRSHA+F I L Q+ 
Sbjct: 165 EDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK 224

Query: 241 KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR 300
           K+   N + R +K+ L+DLAGSER   + A+G R  EG NINR LL LGNVI+AL D K 
Sbjct: 225 KSDK-NSSFR-SKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDK- 281

Query: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360
           K   +PYR+SKLTRLL+DSLGGN  T+MIA VSP+    ++T NTL+YA+RA+ IK+   
Sbjct: 282 KGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKN--- 338

Query: 361 SNVLNVN------NHITQYVKICNEQKAEILLLK---------------EKLKA-YEEQK 398
             ++N++      NH+ Q V     Q+ ++LLL+               E L++  E+ +
Sbjct: 339 KPIVNIDPQTAELNHLKQQV-----QQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQ 393

Query: 399 AFTNENDQAKLMISNPQEKEIERFQEILNCLFQNR------EEIRQ------EYLKLEML 446
           +   EN++    +S    +  +  + I+     N       EE+RQ      +  KL   
Sbjct: 394 SLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVET 453

Query: 447 LKENELKSFYQQQCHKQ 463
           L++ ELK   +  C+ Q
Sbjct: 454 LEDQELKENVEIICNLQ 470


>gi|46852172 kinesin family member 13B [Homo sapiens]
          Length = 1826

 Score =  239 bits (611), Expect = 6e-63
 Identities = 169/443 (38%), Positives = 249/443 (56%), Gaps = 33/443 (7%)

Query: 12  MKVVVRVRPENTKEKAAGFH-KVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNK 70
           +KV VR+RP N +E     H K V  VD + ++ +P    +S    +    Q  +   + 
Sbjct: 6   VKVAVRIRPMNRRE--TDLHTKCVVDVDANKVILNPVNTNLSKGDAR---GQPKVFAYDH 60

Query: 71  DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP 130
               + ++V ++ + Q  VF+   + IL++  +GYN  + AYG TG+GK++TM+G+AD+P
Sbjct: 61  CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP 120

Query: 131 GVMYLTMLHLY-KCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP---LAVREDTQKG 186
           G++      L+ +   E  EE+     VSY+E+YNE++RDLL   G    L VRE +  G
Sbjct: 121 GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLG 180

Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQ-DKTASI 245
             V GL+     S ++I  L+  GNK+RT   T+MN  SSRSHAVF+I L        S 
Sbjct: 181 PYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSG 240

Query: 246 NQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADS---KRKN 302
               ++ K+SL+DLAGSERA+ +GA G R  EG+NIN+SL  LG VI+ALAD    K KN
Sbjct: 241 TSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKN 300

Query: 303 QHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSN 362
           + +PYR+S LT LLKDSLGGN +T M+A VSP++  YD+T +TL+YA+RAK         
Sbjct: 301 KFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAK--------- 351

Query: 363 VLNVNNHITQYVKICNEQKAEILL-LKEKLKAYEEQ--KAFTNENDQAKLMISNPQEKEI 419
                 HI  +  +  +  A I+  L+E+++   EQ  KA   ++ + K  +    EK I
Sbjct: 352 ------HIVNHAVVNEDPNARIIRDLREEVEKLREQLTKAEAMKSPELKDRLEE-SEKLI 404

Query: 420 ERFQEILNCLFQNREEIRQEYLK 442
           +          +  EEI QE  K
Sbjct: 405 QEMTVTWEEKLRKTEEIAQERQK 427


>gi|150010604 kinesin family member 4B [Homo sapiens]
          Length = 1234

 Score =  239 bits (610), Expect = 8e-63
 Identities = 163/432 (37%), Positives = 246/432 (56%), Gaps = 46/432 (10%)

Query: 71  DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGS---- 126
           D  F +D VFD  + Q EVF     P+++    GYN TVLAYG TG+GKT++M G+    
Sbjct: 46  DKSFTYDFVFDPCTEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAE 105

Query: 127 -ADEP--GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGPLA---VR 180
             +EP  G++   +  L+K +D+ K +   +  VSYLE+YNE+I DLL  S   A   +R
Sbjct: 106 QENEPTVGIIPRVIQLLFKEIDK-KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIR 164

Query: 181 EDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQD 240
           ED ++G+ + GLT      + + +  L+ GN +RT   T MN+ SSRSHA+F I + Q+ 
Sbjct: 165 EDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK 224

Query: 241 KTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKR 300
           K+   N + R +K+ L+DLAGSER   + A+G R  EG NINR LL LGNVI+AL D K 
Sbjct: 225 KSDK-NCSFR-SKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDK- 281

Query: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360
           K   +PYR+SKLTRLL+DSLGGN  T+MIA VSP+    ++T +TL+YA+RA+ IK+   
Sbjct: 282 KGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKN--- 338

Query: 361 SNVLNVNNHITQYVKICNE-QKAEILLLK---------------EKLKA-YEEQKAFTNE 403
             ++N++ H  +   +  + Q+ ++LLL+               E L++  E+ ++   E
Sbjct: 339 KPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEE 398

Query: 404 NDQAKLMISNPQEKEIERFQEIL------NCLFQNREEIRQ------EYLKLEMLLKENE 451
           N++    +S    +  +  + I+        L    EE+RQ      +  KL   L++ E
Sbjct: 399 NEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQE 458

Query: 452 LKSFYQQQCHKQ 463
           LK   +  C+ Q
Sbjct: 459 LKENVEIICNLQ 470


>gi|41352705 kinesin family member 3C [Homo sapiens]
          Length = 793

 Score =  239 bits (609), Expect = 1e-62
 Identities = 198/640 (30%), Positives = 324/640 (50%), Gaps = 108/640 (16%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KVV R RP + KE+AAG  +        IL  D K  +V+  + +    +         
Sbjct: 11  LKVVARCRPLSRKEEAAGHEQ--------ILTMDVKLGQVTLRNPRAAPGE-------LP 55

Query: 72  LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP- 130
             F FDAV+D +S Q+++++ T +P++ S L G+N TV AYG TG GKT+TM G+  EP 
Sbjct: 56  KTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPE 115

Query: 131 --GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP--LAVREDTQKG 186
             GV+     H++  +   + ++    A SYLE+Y E+IRDLL       L ++E+ + G
Sbjct: 116 LRGVIPNAFEHIFTHISRSQNQQYLVRA-SYLEIYQEEIRDLLSKEPGKRLELKENPETG 174

Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
           V +  L+    K+ +EI H+++ GN+ R    T MN  SSRSHA+F I +   ++ +   
Sbjct: 175 VYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQ 234

Query: 247 QNVRIAKMSLIDLAGSER------------------------ASTSGAKGTRFVEGTNIN 282
            ++R+ K++L+DLAGSER                         S  GA G R  E + IN
Sbjct: 235 DHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKIN 294

Query: 283 RSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDT 342
            SL ALGNVI ALA ++  + HIPYR+SKLTRLL+DSLGGN +TIM+A + P+S  YD++
Sbjct: 295 LSLSALGNVIAALAGNR--STHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDES 352

Query: 343 YNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEI-----LLLKEKLKAYEEQ 397
            +TL++ANRAK+IK+  + N    +  + ++ +     KA++     L  + + K+   +
Sbjct: 353 LSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRK 412

Query: 398 KAFT---------------------NENDQ----------AKLMISNPQEKEIERFQEIL 426
           KA +                     N N+            +  + N  +++ ER +E  
Sbjct: 413 KAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEK 472

Query: 427 NCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKA---TGKR--- 480
             +  +R  + +E  KL +  KE  L+   ++Q  +  E++ ++ K  ++    G R   
Sbjct: 473 AAIQDDRSLVSEEKQKL-LEEKEKMLEDLRREQ--QATELLAAKYKAMESKLLIGGRNIM 529

Query: 481 DH-----RLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELK-K 534
           DH     ++  LK +    +KRRE E++Q       + R E+ M L      + +E++ K
Sbjct: 530 DHTNEQQKMLELKRQEIAEQKRREREMQQ-----EMMLRDEETMELRGTYTSLQQEVEVK 584

Query: 535 DLHCHHLHLQNKDLKAQIRHMMD-----LACLQEQQHRQT 569
                 L+ + + +KA+I+   D        L+E Q+ QT
Sbjct: 585 TKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQT 624


>gi|30794488 kinesin family member 27 [Homo sapiens]
          Length = 1401

 Score =  237 bits (605), Expect = 3e-62
 Identities = 151/400 (37%), Positives = 219/400 (54%), Gaps = 47/400 (11%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV VR+RP   KE        V V+        P  ++V                  +D
Sbjct: 6   VKVAVRIRPLLCKEALHNHQVCVRVI--------PNSQQVII---------------GRD 42

Query: 72  LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGS----- 126
             F FD VF + STQ EV+    KP++ S + GYN TV AYG TG+GKT+T+ G      
Sbjct: 43  RVFTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASV 102

Query: 127 -ADEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL---VNSGPLAVRED 182
              + G++   +  +++ + E       +  VSY+EVY E +RDLL    +   L +RED
Sbjct: 103 VEGQKGIIPRAIQEIFQSISEHPSIDF-NVKVSYIEVYKEDLRDLLELETSMKDLHIRED 161

Query: 183 TQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKT 242
            +   V+ G      +S+ E++ LL+ GN  R    T MN  SSRSHA+F I + Q  K 
Sbjct: 162 EKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKN 221

Query: 243 ASINQNVR-------IAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINAL 295
               ++         ++K   +DLAGSER + +G  G RF E   IN  LLALGNVI+AL
Sbjct: 222 MEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISAL 281

Query: 296 ADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDI 355
            D +RK+ HIPYR++K+TRLLKDSLGG+ +T+MI  VSPSS  +D++ N+LKYANRA++I
Sbjct: 282 GDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNI 341

Query: 356 KSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYE 395
           ++    N    ++ I       +E + EI LL+E L++ +
Sbjct: 342 RNKPTVNFSPESDRI-------DEMEFEIKLLREALQSQQ 374


>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
          Length = 1690

 Score =  234 bits (598), Expect = 2e-61
 Identities = 155/404 (38%), Positives = 228/404 (56%), Gaps = 46/404 (11%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV VRVRP N++E +     ++ +      + +PKQ                 K+  K 
Sbjct: 6   VKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQP----------------KETPKS 49

Query: 72  LKFVFDAVFDETS-------TQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTML 124
             F + + +  TS       +Q +V+    + +L+    GYN  + AYG TGAGK++TM+
Sbjct: 50  FSFDY-SYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMM 108

Query: 125 GSA--DEPGVMYLTMLHLYKCMDEIKEEKIC-STAVSYLEVYNEQIRDLL--VNSGPLAV 179
           G    D+ G++      L+  +++   + +  S  VSY+E+Y E++RDLL   N G L V
Sbjct: 109 GKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRV 168

Query: 180 REDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQ 239
           RE    G  V  L+     S  +I  L+D+GNK RT   T+MN TSSRSHAVF I   Q+
Sbjct: 169 REHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQK 228

Query: 240 DKTASINQNV-RIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD- 297
              A  N    +++K+SL+DLAGSERA ++GAKGTR  EG NIN+SL  LG VI+ALA+ 
Sbjct: 229 RHDAETNITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEM 288

Query: 298 --------SKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYA 349
                    K+K   IPYR+S LT LL+++LGGN +T M+AA+SP+ + YD+T +TL+YA
Sbjct: 289 DSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYA 348

Query: 350 NRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKA 393
           +RAK I+ +   N  + NN      K+  E K E+  L++ L A
Sbjct: 349 DRAKQIRCNAVINE-DPNN------KLIRELKDEVTRLRDLLYA 385


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score =  234 bits (596), Expect = 4e-61
 Identities = 170/464 (36%), Positives = 245/464 (52%), Gaps = 47/464 (10%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV VRVRP N +EK      ++ +      + + K  E     G   + +   K    D
Sbjct: 4   VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPE----GGTGDSGRERTKTFTYD 59

Query: 72  LKFVF-DAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP 130
             F   D    +  +Q  VF+     +++S   GYN  V AYG TG+GK++TM+G++ + 
Sbjct: 60  FSFYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS 119

Query: 131 GVMYLTMLHLYKCMDEIK--EEKICSTAVSYLEVYNEQIRDLLVNSGP----LAVREDTQ 184
           G++      L+  ++E    +E    T VSYLE+YNE++RDLL         L VRE  +
Sbjct: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179

Query: 185 KGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTAS 244
           +G  V  L+ H  ++  ++  L+D GN NRT   T MN  SSRSHA+F I   Q  K  S
Sbjct: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQA-KFDS 238

Query: 245 INQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD------- 297
                 ++K+ L+DLAGSERA  +GA G R  EG NIN+SL+ LGNVI+ALAD       
Sbjct: 239 EMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAAN 298

Query: 298 --SKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDI 355
             +K+K   +PYR+S LT LLKDSLGGN +TIMIA +SP+ V Y +T +TL+YANRAK+I
Sbjct: 299 TLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNI 358

Query: 356 KSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQ 415
              +    +N + +    VK+  E +AEI  LK  L           + +Q  L+ S   
Sbjct: 359 ---INKPTINEDAN----VKLIRELRAEIARLKTLLA----------QGNQIALLDSPTA 401

Query: 416 EKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQ 459
               E+ Q+          E R + L  E   K NE ++  ++Q
Sbjct: 402 LSMEEKLQQ---------NEARVQELTKEWTNKWNETQNILKEQ 436



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 57/281 (20%), Positives = 122/281 (43%), Gaps = 37/281 (13%)

Query: 348 YANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQA 407
           +   A  ++   KS +L+  +     +    E  + ++L    L+   +Q+    + +  
Sbjct: 553 HPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESK 612

Query: 408 KLMISNPQEK------EIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCH 461
           + +I   +EK      E+ER Q+ +    +  E ++ +  K E  LK    +SF+ +  +
Sbjct: 613 RKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKR---RSFHIE--N 667

Query: 462 KQIEMMCSEDKVEKATGKRDHRLAMLKTRR---SYLEKRREEELKQFDENTNWLHRVEKE 518
           K  +++  ++K E+   +    + + K R+   ++L  R +EEL++  E  N  +   ++
Sbjct: 668 KLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFL--RVQEELQRLKELNN--NEKAEK 723

Query: 519 MGLLSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNAL-- 576
             +  +   + KE  KD     L L+ K L+ Q +  + L    E+Q R+ + ++  L  
Sbjct: 724 FQIFQELDQLQKE--KDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRR 781

Query: 577 ------------LPTLRKQYCTLKEAGLSNAAFESDFKEIE 605
                       L  +R+    +KEA    A  + D +E+E
Sbjct: 782 GEVQWVEEEKRDLEGIRESLLRVKEA---RAGGDEDGEELE 819


>gi|83716024 kinesin family member 21B [Homo sapiens]
          Length = 1624

 Score =  233 bits (595), Expect = 5e-61
 Identities = 162/439 (36%), Positives = 222/439 (50%), Gaps = 73/439 (16%)

Query: 7   DLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIK 66
           D C  +KV VR+RP+ +KEK  G H    V         P + +V               
Sbjct: 6   DCC--VKVAVRIRPQLSKEKIEGCHICTSVT--------PGEPQVLL------------- 42

Query: 67  KQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTM--- 123
              KD  F +D VFD  + Q +++      ++     GYN TVLAYG TGAGKT+TM   
Sbjct: 43  --GKDKAFTYDFVFDLDTWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTG 100

Query: 124 ---LGSADEPGVMYLTMLHLYKCMDEIK----EEKICS----TAVSYLEVYNEQIRDLLV 172
                S +E G++   + HL+  + E K    E+ +       +  +LE+YNE+I DL  
Sbjct: 101 FDMATSEEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFD 160

Query: 173 NS---------GPLAVREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNA 223
           ++           + + ED   G+   G+T     S EE++  L  G  +RT   T MN 
Sbjct: 161 STRDPDTRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNV 220

Query: 224 TSSRSHAVFQIYLRQQDKTAS---INQNVR---------------IAKMSLIDLAGSERA 265
            SSRSHA+F I+L Q         +N+ V                 AK   +DLAGSER 
Sbjct: 221 QSSRSHAIFTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERL 280

Query: 266 STSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQ 325
             +GA G R  EG +IN  LLALGNVI+AL D  +K  H+PYR+SKLTRLL+DSLGGN Q
Sbjct: 281 KRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQ 340

Query: 326 TIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEIL 385
           TIMIA VSPS   + +T NTLKYANRA++IK+ +  N    +  I+         +AEI 
Sbjct: 341 TIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISAL-------RAEIA 393

Query: 386 LLKEKLKAYEEQKAFTNEN 404
            L+ +L  Y+  K    E+
Sbjct: 394 RLQMELMEYKAGKRVIGED 412



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 50/230 (21%), Positives = 98/230 (42%), Gaps = 27/230 (11%)

Query: 412 SNPQEKEIERFQEI--LNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCS 469
           S+P+EKE+    ++  L C  + ++++  E    +  L+   LK  Y+++      ++  
Sbjct: 623 SDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQT--LKHQYEEK------LILL 674

Query: 470 EDKVEKATGKRDHRLAMLKTRRSYLEKRR-------EEELKQFDENTNWLHRVEKEMG-L 521
           ++K+     +RD  L  L T   Y E++        E+ L++ + +   L   +KE   L
Sbjct: 675 QNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARL 734

Query: 522 LSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLR 581
           L       +ELKK      L  +  ++K     +M     ++Q+ R  E   N  +  L+
Sbjct: 735 LKNQSRYERELKK------LQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLK 788

Query: 582 KQYCTLKEAGLSNAAFESDFKEIEHLVERKKVVVWADQTAEQPKQNDLPG 631
           K+    +       A ES  ++ E ++ RK   V A +   +P    + G
Sbjct: 789 KEQ---RRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAG 835


>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
          Length = 1749

 Score =  233 bits (594), Expect = 6e-61
 Identities = 169/456 (37%), Positives = 249/456 (54%), Gaps = 46/456 (10%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV VRVRP N +E       VV +     ++  P                N  + + K 
Sbjct: 6   VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPS--------------NTKQGERKP 51

Query: 72  LK-FVFDAVF---DETST-----QSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHT 122
            K F FD  F   DE++T     Q  VF+   + IL     GYN  + AYG TG+GK+ +
Sbjct: 52  PKVFAFDYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFS 111

Query: 123 MLGSADEPGVMYLTMLHLYKCMD-EIKEEKICSTAVSYLEVYNEQIRDLLVNSGP---LA 178
           M+G A++ G++      L+K +  E  E +     VSY+E+YNE++RDLL   G    L 
Sbjct: 112 MMGHAEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK 171

Query: 179 VREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQ 238
           VRE    G  V GL+     S E+I  L+  GNK+RT   T+MN  SSRSHAVF I + Q
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231

Query: 239 Q-DKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD 297
                 S N   +++K+SL+DLAGSER S +GA G R  EG+NIN+SL  LG VI++LAD
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291

Query: 298 S---KRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKD 354
               K K++ +PYR+S LT LLKD+LGGN QT MIA +SP++  Y++T +TL+YA+RAK 
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351

Query: 355 IKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKA-----FTNENDQAKL 409
           I   +   V+N + +     K+  E + E+  L+E+L   E  KA        E+++   
Sbjct: 352 I---VNHAVVNEDPN----AKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIK 404

Query: 410 MISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEM 445
            ++   E+++ + +EI     + + ++    + LEM
Sbjct: 405 ELTVTWEEKLRKTEEIAQ---ERQRQLESMGISLEM 437


>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
          Length = 1757

 Score =  233 bits (594), Expect = 6e-61
 Identities = 169/456 (37%), Positives = 249/456 (54%), Gaps = 46/456 (10%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV VRVRP N +E       VV +     ++  P                N  + + K 
Sbjct: 6   VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPS--------------NTKQGERKP 51

Query: 72  LK-FVFDAVF---DETST-----QSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHT 122
            K F FD  F   DE++T     Q  VF+   + IL     GYN  + AYG TG+GK+ +
Sbjct: 52  PKVFAFDYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFS 111

Query: 123 MLGSADEPGVMYLTMLHLYKCMD-EIKEEKICSTAVSYLEVYNEQIRDLLVNSGP---LA 178
           M+G A++ G++      L+K +  E  E +     VSY+E+YNE++RDLL   G    L 
Sbjct: 112 MMGHAEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK 171

Query: 179 VREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQ 238
           VRE    G  V GL+     S E+I  L+  GNK+RT   T+MN  SSRSHAVF I + Q
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231

Query: 239 Q-DKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD 297
                 S N   +++K+SL+DLAGSER S +GA G R  EG+NIN+SL  LG VI++LAD
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291

Query: 298 S---KRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKD 354
               K K++ +PYR+S LT LLKD+LGGN QT MIA +SP++  Y++T +TL+YA+RAK 
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351

Query: 355 IKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKA-----FTNENDQAKL 409
           I   +   V+N + +     K+  E + E+  L+E+L   E  KA        E+++   
Sbjct: 352 I---VNHAVVNEDPN----AKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIK 404

Query: 410 MISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEM 445
            ++   E+++ + +EI     + + ++    + LEM
Sbjct: 405 ELTVTWEEKLRKTEEIAQ---ERQRQLESMGISLEM 437


>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
          Length = 1770

 Score =  233 bits (594), Expect = 6e-61
 Identities = 169/456 (37%), Positives = 249/456 (54%), Gaps = 46/456 (10%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV VRVRP N +E       VV +     ++  P                N  + + K 
Sbjct: 6   VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPS--------------NTKQGERKP 51

Query: 72  LK-FVFDAVF---DETST-----QSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHT 122
            K F FD  F   DE++T     Q  VF+   + IL     GYN  + AYG TG+GK+ +
Sbjct: 52  PKVFAFDYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFS 111

Query: 123 MLGSADEPGVMYLTMLHLYKCMD-EIKEEKICSTAVSYLEVYNEQIRDLLVNSGP---LA 178
           M+G A++ G++      L+K +  E  E +     VSY+E+YNE++RDLL   G    L 
Sbjct: 112 MMGHAEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK 171

Query: 179 VREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQ 238
           VRE    G  V GL+     S E+I  L+  GNK+RT   T+MN  SSRSHAVF I + Q
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231

Query: 239 Q-DKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD 297
                 S N   +++K+SL+DLAGSER S +GA G R  EG+NIN+SL  LG VI++LAD
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291

Query: 298 S---KRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKD 354
               K K++ +PYR+S LT LLKD+LGGN QT MIA +SP++  Y++T +TL+YA+RAK 
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351

Query: 355 IKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKA-----FTNENDQAKL 409
           I   +   V+N + +     K+  E + E+  L+E+L   E  KA        E+++   
Sbjct: 352 I---VNHAVVNEDPN----AKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIK 404

Query: 410 MISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEM 445
            ++   E+++ + +EI     + + ++    + LEM
Sbjct: 405 ELTVTWEEKLRKTEEIAQ---ERQRQLESMGISLEM 437


>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
          Length = 1805

 Score =  233 bits (594), Expect = 6e-61
 Identities = 169/456 (37%), Positives = 249/456 (54%), Gaps = 46/456 (10%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV VRVRP N +E       VV +     ++  P                N  + + K 
Sbjct: 6   VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPS--------------NTKQGERKP 51

Query: 72  LK-FVFDAVF---DETST-----QSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHT 122
            K F FD  F   DE++T     Q  VF+   + IL     GYN  + AYG TG+GK+ +
Sbjct: 52  PKVFAFDYCFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFS 111

Query: 123 MLGSADEPGVMYLTMLHLYKCMD-EIKEEKICSTAVSYLEVYNEQIRDLLVNSGP---LA 178
           M+G A++ G++      L+K +  E  E +     VSY+E+YNE++RDLL   G    L 
Sbjct: 112 MMGHAEQLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLK 171

Query: 179 VREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQ 238
           VRE    G  V GL+     S E+I  L+  GNK+RT   T+MN  SSRSHAVF I + Q
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231

Query: 239 Q-DKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD 297
                 S N   +++K+SL+DLAGSER S +GA G R  EG+NIN+SL  LG VI++LAD
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291

Query: 298 S---KRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKD 354
               K K++ +PYR+S LT LLKD+LGGN QT MIA +SP++  Y++T +TL+YA+RAK 
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351

Query: 355 IKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKA-----FTNENDQAKL 409
           I   +   V+N + +     K+  E + E+  L+E+L   E  KA        E+++   
Sbjct: 352 I---VNHAVVNEDPN----AKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIK 404

Query: 410 MISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEM 445
            ++   E+++ + +EI     + + ++    + LEM
Sbjct: 405 ELTVTWEEKLRKTEEIAQ---ERQRQLESMGISLEM 437


>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
          Length = 1028

 Score =  233 bits (594), Expect = 6e-61
 Identities = 141/356 (39%), Positives = 201/356 (56%), Gaps = 24/356 (6%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KVVVR RP N +E+      VV V        D  + +           QN        
Sbjct: 6   VKVVVRCRPMNQRERELRCQPVVTV--------DCARAQCCI--------QNPGAADEPP 49

Query: 72  LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP- 130
            +F FD  +       +++     P++     GYN T+ AYG TG+GK+ TM G  D P 
Sbjct: 50  KQFTFDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPS 109

Query: 131 --GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLV--NSGPLAVREDTQKG 186
             G++     H+++ +   +  K    A SYLE+YNE +RDLL       L ++E  +KG
Sbjct: 110 QRGIIPRAFEHVFESVQCAENTKFLVRA-SYLEIYNEDVRDLLGADTKQKLELKEHPEKG 168

Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
           V V GL++H   S  +  H+++ G KNR+   T MN  SSRSH++F I +          
Sbjct: 169 VYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGK 228

Query: 247 QNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIP 306
            ++R  K++L+DLAGSER S +GA G R  E T IN SL ALGNVI+AL D + K  H+P
Sbjct: 229 DHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCK--HVP 286

Query: 307 YRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSN 362
           YR+SKLTRLL+DSLGGN +T+M+A +SP+   YD+T +TL+YANRAK+I++  + N
Sbjct: 287 YRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN 342


>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
          Length = 1029

 Score =  233 bits (594), Expect = 6e-61
 Identities = 141/356 (39%), Positives = 201/356 (56%), Gaps = 24/356 (6%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KVVVR RP N +E+      VV V        D  + +           QN        
Sbjct: 6   VKVVVRCRPMNQRERELRCQPVVTV--------DCARAQCCI--------QNPGAADEPP 49

Query: 72  LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP- 130
            +F FD  +       +++     P++     GYN T+ AYG TG+GK+ TM G  D P 
Sbjct: 50  KQFTFDGAYHVDHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPS 109

Query: 131 --GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLV--NSGPLAVREDTQKG 186
             G++     H+++ +   +  K    A SYLE+YNE +RDLL       L ++E  +KG
Sbjct: 110 QRGIIPRAFEHVFESVQCAENTKFLVRA-SYLEIYNEDVRDLLGADTKQKLELKEHPEKG 168

Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
           V V GL++H   S  +  H+++ G KNR+   T MN  SSRSH++F I +          
Sbjct: 169 VYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGK 228

Query: 247 QNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIP 306
            ++R  K++L+DLAGSER S +GA G R  E T IN SL ALGNVI+AL D + K  H+P
Sbjct: 229 DHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCK--HVP 286

Query: 307 YRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSN 362
           YR+SKLTRLL+DSLGGN +T+M+A +SP+   YD+T +TL+YANRAK+I++  + N
Sbjct: 287 YRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN 342


>gi|203096856 kinesin family member 7 [Homo sapiens]
          Length = 1343

 Score =  232 bits (592), Expect = 1e-60
 Identities = 136/308 (44%), Positives = 186/308 (60%), Gaps = 17/308 (5%)

Query: 70  KDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSA-- 127
           +D  F F  V  E + Q  V++   +P+L +F  G+N TV AYG TG+GKT+TM G A  
Sbjct: 51  RDRHFGFHVVLAEDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASV 109

Query: 128 -----DEPGVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL---VNSGPLAV 179
                DE G++   M   +K +DE  +   C   VSYLEVY E+ RDLL     S  + +
Sbjct: 110 ASLLEDEQGIVPRAMAEAFKLIDE-NDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQL 168

Query: 180 REDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQ 239
           RED +  VV+ G+     +  +E+L LL+ GN  R    T +N  SSRSH VF + L Q+
Sbjct: 169 REDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQR 228

Query: 240 DKTAS-----INQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINA 294
            +  S         + ++K   +DLAGSER   +G+ G R  E   IN SLLALGNVI+A
Sbjct: 229 GRAPSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISA 288

Query: 295 LADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKD 354
           L D +R+  HIPYR+SK+TR+LKDSLGGN +T+MIA VSPSS  +D+T NTL YA+RA++
Sbjct: 289 LGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQN 348

Query: 355 IKSSLKSN 362
           I++    N
Sbjct: 349 IRNRATVN 356


>gi|38569484 kinesin family member 21A [Homo sapiens]
          Length = 1661

 Score =  231 bits (590), Expect = 2e-60
 Identities = 156/433 (36%), Positives = 217/433 (50%), Gaps = 71/433 (16%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           ++V VR+RP+  KEK  G H    V      VF                         KD
Sbjct: 10  VRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVF-----------------------LGKD 46

Query: 72  LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSAD--- 128
             F FD VFD  S Q +++    + ++     GYN TV AYG TGAGKT+TM    D   
Sbjct: 47  KAFTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNI 106

Query: 129 ---EPGVMYLTMLHLYKCMDEIKEEKICS--------TAVSYLEVYNEQIRDLLVNS--- 174
              E G++   + HL+K ++E K   I +            +LE+YNE++ DL   +   
Sbjct: 107 VEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDI 166

Query: 175 ------GPLAVREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRS 228
                   + + ED+  G+   G+T     +  E++  L  G  +RT   T MN  SSRS
Sbjct: 167 DAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRS 226

Query: 229 HAVFQIYLRQQ-----------------DKTASINQ-NVRIAKMSLIDLAGSERASTSGA 270
           HA+F I++ Q                   ++A +N+     AK   +DLAGSER   +GA
Sbjct: 227 HAIFTIHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGA 286

Query: 271 KGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIA 330
            G R  EG +IN  LLALGNVI+AL D  ++  H+PYR+SKLTRLL+DSLGGN QTIMIA
Sbjct: 287 TGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIA 346

Query: 331 AVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEK 390
            VSPS   + +T NTLKYANRA++IK+ +  N    +  I       N  ++EI  L+ +
Sbjct: 347 CVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQI-------NALRSEITRLQME 399

Query: 391 LKAYEEQKAFTNE 403
           L  Y+  K   +E
Sbjct: 400 LMEYKTGKRIIDE 412



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 29/137 (21%), Positives = 71/137 (51%), Gaps = 15/137 (10%)

Query: 380 QKAEILLLKEKLKAYEEQKAFTNEND-QAKLMISNPQEKEIERFQEILNCLFQNREEIRQ 438
           ++ ++L     +++Y E+KA    ++ + KL   N + + ++  Q+    L +N+ +  +
Sbjct: 682 ERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEK 741

Query: 439 EYLKLE---MLLKENELKSFYQQQCHKQIEMMCSEDK-------VEKATGKRDHRLAMLK 488
           +  KL+   M +K+ +++   Q +  +Q +   +E +       ++K   KRDH+L +L+
Sbjct: 742 QLKKLQQDVMEMKKTKVRLMKQMK-EEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLE 800

Query: 489 TRRSYLE---KRREEEL 502
            ++   E   +R+ EE+
Sbjct: 801 AQKRNQEVVLRRKTEEV 817


>gi|13699824 kinesin family member 11 [Homo sapiens]
          Length = 1056

 Score =  231 bits (589), Expect = 2e-60
 Identities = 182/577 (31%), Positives = 286/577 (49%), Gaps = 63/577 (10%)

Query: 5   EEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNV 64
           +E+   +++VVVR RP N  E+ A  H +V          DP ++EVS   G        
Sbjct: 12  KEEKGKNIQVVVRCRPFNLAERKASAHSIVEC--------DPVRKEVSVRTGG------- 56

Query: 65  IKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTML 124
           +  ++    + FD VF  ++ Q +V+     PIL   + GYNCT+ AYG TG GKT TM 
Sbjct: 57  LADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTME 116

Query: 125 GSA---------DEP--GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVN 173
           G           ++P  G++  T+  +++ + +   E   S  VS LE+YNE++ DLL  
Sbjct: 117 GERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTE--FSVKVSLLEIYNEELFDLLNP 174

Query: 174 SGPLAVRED------TQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSR 227
           S  ++ R         ++GV++ GL      + +E+  +L+ G   RT   T MNA SSR
Sbjct: 175 SSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSR 234

Query: 228 SHAVFQIYLRQQDKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLA 287
           SH+VF + +  ++ T    + V+I K++L+DLAGSE    SGA   R  E  NIN+SLL 
Sbjct: 235 SHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLT 294

Query: 288 LGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLK 347
           LG VI AL +   +  H+PYR SKLTR+L+DSLGG  +T +IA +SP+S+  ++T +TL+
Sbjct: 295 LGRVITALVE---RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLE 351

Query: 348 YANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQA 407
           YA+RAK+I      N   VN  +T+   I  E   EI  LK  L A  E+       +  
Sbjct: 352 YAHRAKNI-----LNKPEVNQKLTKKALI-KEYTEEIERLKRDLAAAREKNGVYISEENF 405

Query: 408 KLMIS--NPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIE 465
           ++M      QE++I    E +  + +    + + ++       +NEL      QC   ++
Sbjct: 406 RVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMD-----NKNEL-----DQCKSDLQ 455

Query: 466 MMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREE-ELKQFDENTNWLHRVEKEMGLLSQ 524
               E    + T K      +   +  Y+    E  E K  D  +  L+ VE+    +S 
Sbjct: 456 NKTQE---LETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETTKDVS- 511

Query: 525 NGHIPKELKKDLHCHHLHLQN---KDLKAQIRHMMDL 558
             H   + KK +  H+   Q+   K+L +   +M +L
Sbjct: 512 GLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEEL 548


>gi|40254834 kinesin family member 1C [Homo sapiens]
          Length = 1103

 Score =  227 bits (579), Expect = 3e-59
 Identities = 154/400 (38%), Positives = 227/400 (56%), Gaps = 44/400 (11%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV VRVRP N +E +     VV +      + +PKQ +                  +  
Sbjct: 6   VKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSK------------------DAP 47

Query: 72  LKFVFD-AVFDETST-------QSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTM 123
             F FD + +  TST       Q +V+    + +L     GYN  + AYG TGAGK++TM
Sbjct: 48  KSFTFDYSYWSHTSTEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTM 107

Query: 124 LGSAD--EPGVMYLTMLHLYKCMDEIKEEKIC-STAVSYLEVYNEQIRDLL--VNSGPLA 178
           +G  +  + G++      L+  + E +  ++  S  VSY+E+Y E++RDLL   + G L 
Sbjct: 108 MGRQEPGQQGIVPQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLR 167

Query: 179 VREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQ 238
           VRE    G  V  L+     S  +I  L+D GNK RT   T+MN TSSRSHAVF I   Q
Sbjct: 168 VREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQ 227

Query: 239 Q--DKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALA 296
           +  D+   ++   +++K+SL+DLAGSERA +SGA+G R  EG NIN+SL  LG VI+ALA
Sbjct: 228 RCHDQLTGLDSE-KVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALA 286

Query: 297 D---SKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAK 353
           D    KRK+  IPYR+S LT LLK++LGGN +T MIAA+SP+ + Y++T +TL+YA+R K
Sbjct: 287 DMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTK 346

Query: 354 DIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKA 393
            I+ +    ++N + +     ++  E + E+  L+E L A
Sbjct: 347 QIRCNA---IINEDPN----ARLIRELQEEVARLRELLMA 379


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score =  222 bits (566), Expect = 1e-57
 Identities = 151/438 (34%), Positives = 238/438 (54%), Gaps = 41/438 (9%)

Query: 14  VVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKDLK 73
           V VRVRP N++E++ G                    E +  + K  T+ NVI + +    
Sbjct: 9   VCVRVRPLNSREESLG--------------------ETAQVYWK--TDNNVIYQVDGSKS 46

Query: 74  FVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPGVM 133
           F FD VF    T   V+E    PI+ S + GYN T+ AYG T +GKT+TM+GS D  GV+
Sbjct: 47  FNFDRVFHGNETTKNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVI 106

Query: 134 YLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNS---GPLAVREDTQKGVVVH 190
              +  +++ + +  + +     VSY+E+YNE I DLL  +    PL +RED  + V V 
Sbjct: 107 PRAIHDIFQKIKKFPDREFL-LRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVA 165

Query: 191 GLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYL--RQQDKTASINQN 248
            LT     +SE  L  +  G K+R    T MN  SSRSH +F++ L  R++ + ++   +
Sbjct: 166 DLTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGS 225

Query: 249 VRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYR 308
           V+++ ++L+DLAGSERA+ +GA G R  EG NINRSL  LG VI  L+D  +    I YR
Sbjct: 226 VKVSHLNLVDLAGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDG-QVGGFINYR 284

Query: 309 NSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNN 368
           +SKLTR+L++SLGGN +T +I  ++P  V +D+T   L++A+ AK +K++   N ++ + 
Sbjct: 285 DSKLTRILQNSLGGNAKTRIICTITP--VSFDETLTALQFASTAKYMKNTPYVNEVSTDE 342

Query: 369 HITQYVKICNEQKAEILLLKEKLKAYE-EQKAFTNENDQAKLMISNP---QEKEIERFQE 424
                  +    + EI+ LK++L+    E +A   E DQ   ++      Q+ + E+ + 
Sbjct: 343 ------ALLKRYRKEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIEN 396

Query: 425 ILNCLFQNREEIRQEYLK 442
           +   L  +     Q+ LK
Sbjct: 397 LTRMLVTSSSLTLQQELK 414



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 50/228 (21%), Positives = 99/228 (43%), Gaps = 22/228 (9%)

Query: 388  KEKLKAYEEQKAFTNENDQAKLMISNPQEKEIERFQE--ILNCLFQNREEIRQEYLKLEM 445
            KEK      Q+   +E+DQ K  I     K +E  +E  + +C  + +EE   E L++ +
Sbjct: 1442 KEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINE-LRVNL 1500

Query: 446  LLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEELKQF 505
              KE E+ +       KQ+E +   DK++    +   +      ++    + +  ELKQF
Sbjct: 1501 SEKETEISTI-----QKQLEAI--NDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQF 1553

Query: 506  DENTNWLHRVEKEMGLLSQNG---HIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQ 562
             E     HR  K+  L S       +   L++      + ++ K+   +++  + +   +
Sbjct: 1554 KE-----HRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIE--R 1606

Query: 563  EQQHRQTEAVLNALLPTLRKQYCTLKEAGLSNAAFESDFKEIEHLVER 610
            +Q    T+ ++  +  +  K+Y  LK   ++    +    EIEHL E+
Sbjct: 1607 DQLKENTKEIVAKMKESQEKEYQFLKMTAVNET--QEKMCEIEHLKEQ 1652



 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 68/311 (21%), Positives = 140/311 (45%), Gaps = 43/311 (13%)

Query: 347  KYANRAKDIK-SSLKSNVLNVNNHITQY---VKICNEQKAEILLLKEKLKAYEEQKAFTN 402
            K   +AKD    S++S +L + N + +    ++I  ++K E+  ++E L+   +Q     
Sbjct: 1554 KEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENT 1613

Query: 403  ENDQAKLM--------------ISNPQEK--EIERFQEILNCLFQNREEIRQEYLKLEML 446
            +   AK+               ++  QEK  EIE  +E       N E I  E ++L  +
Sbjct: 1614 KEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQI 1673

Query: 447  LKEN--ELKSFYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEE--- 501
            L EN  E++S  +++    +  +    KVE+   K + R  + +     LEK+ E +   
Sbjct: 1674 LHENLEEMRSVTKER--DDLRSVEETLKVERDQLKENLRETITRD----LEKQEELKIVH 1727

Query: 502  --LKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLA 559
              LK+  E       ++K  G++S+  +    ++KDL   +  L+ +DLK  I+  + +A
Sbjct: 1728 MHLKEHQET------IDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLK--IQEELRIA 1779

Query: 560  CLQEQQHRQTEAVLNALLPTLRKQYCTL-KEAGLSNAAFESDFKEIEHLVERKKVVVWAD 618
             +  ++ ++T   L  ++     +   + K+   SNA  +   +E++   E + + +  D
Sbjct: 1780 HMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELK-ANEHQLITLKKD 1838

Query: 619  QTAEQPKQNDL 629
                Q K +++
Sbjct: 1839 VNETQKKVSEM 1849



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 40/213 (18%), Positives = 86/213 (40%), Gaps = 43/213 (20%)

Query: 341  DTYNTLKYANRAKDIKSSLKSNVLNV------NNHITQYVKICNEQKAEILLLKEKLKAY 394
            D   T K  +  + +K  +K   L +      N ++ Q +    E+   ++  ++ L+  
Sbjct: 1838 DVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRV 1897

Query: 395  EEQKAFTNENDQAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENE--L 452
            EE      E DQ K  +   + +++               EI+QE     ML KE++  +
Sbjct: 1898 EETLKL--ERDQLKESLQETKARDL---------------EIQQELKTARMLSKEHKETV 1940

Query: 453  KSFYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEELKQFDENTNWL 512
                ++   K I++   +  ++K+  +   ++  L        +++E +L +  E+ N  
Sbjct: 1941 DKLREKISEKTIQISDIQKDLDKSKDELQKKIQEL--------QKKELQLLRVKEDVNMS 1992

Query: 513  HRVEKEMGLLSQNGHIPKELKKDLHCHHLHLQN 545
            H+   EM          ++LKK     +L +Q+
Sbjct: 1993 HKKINEM----------EQLKKQFEAQNLSMQS 2015



 Score = 30.4 bits (67), Expect = 7.7
 Identities = 43/202 (21%), Positives = 89/202 (44%), Gaps = 25/202 (12%)

Query: 355 IKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAY-EEQKAFTNE---------N 404
           +K+S  ++  N+  +IT         K  I LL+E  ++   E   F+N          N
Sbjct: 431 MKNSNYADQFNIPTNITT-----KTHKLSINLLREIDESVCSESDVFSNTLDTLSEIEWN 485

Query: 405 DQAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKE-NELKSF--YQQQCH 461
              KL+     E E+   +   + L  + E++R E  ++E+ LKE N+L  F   +++  
Sbjct: 486 PATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTK 545

Query: 462 KQIEMMCSED-----KVEKATGKRDHRLAMLKTRRSYLEKRREEELKQFDE--NTNWLHR 514
           K  EM    +      + K     +  L    + +  L + +E+++K+  E  ++  L  
Sbjct: 546 KDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLEN 605

Query: 515 VEKEMGLLSQNGHIPKELKKDL 536
           ++ ++    ++   PK++K+ L
Sbjct: 606 IKMDLSYSLESIEDPKQMKQTL 627


>gi|4758650 kinesin family member 5C [Homo sapiens]
          Length = 957

 Score =  221 bits (564), Expect = 2e-57
 Identities = 195/591 (32%), Positives = 284/591 (48%), Gaps = 63/591 (10%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV+ R RP N  E   G        DK I    PK      F G +T    V+  Q K 
Sbjct: 9   IKVMCRFRPLNEAEILRG--------DKFI----PK------FKGDET----VVIGQGKP 46

Query: 72  LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPG 131
             +VFD V    +TQ +V+    K I++  L GYN T+ AYG T +GKTHTM G   +P 
Sbjct: 47  --YVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQ 104

Query: 132 VMYLTML-------HLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL-VNSGPLAVREDT 183
           +M +          H+Y  MDE  E  I    VSY E+Y ++IRDLL V+   LAV ED 
Sbjct: 105 LMGIIPRIAHDIFDHIYS-MDENLEFHI---KVSYFEIYLDKIRDLLDVSKTNLAVHEDK 160

Query: 184 QKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTA 243
            +   V G T     S EE++ ++D G  NR    T+MN  SSRSH++F I ++Q++   
Sbjct: 161 NRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVET 220

Query: 244 SINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQ 303
               +    K+ L+DLAGSE+ S +GA+G    E  NIN+SL ALGNVI+ALA+  +   
Sbjct: 221 EKKLS---GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKT-- 275

Query: 304 HIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNV 363
           H+PYR+SK+TR+L+DSLGGNC+T ++   SPS     +T +TL +  RAK IK     N 
Sbjct: 276 HVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIK-----NT 330

Query: 364 LNVNNHIT--QYVKICNEQKAEILLLKEKLKAYE-EQKAFTN-ENDQAKLMISNPQEKEI 419
           ++VN  +T  ++ K   ++K +   LK  ++  E E   + N E       IS   +K +
Sbjct: 331 VSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNL 390

Query: 420 ERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGK 479
           E        +  N   +       E    + E+ S Y+Q   K  E+       EK   +
Sbjct: 391 EPCDN--TPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQ 448

Query: 480 R-DHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELKKDLH- 537
             D    +  TRR Y EK +EE  +   EN      V++ +  L +      +  +++  
Sbjct: 449 MLDQDELLASTRRDY-EKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVED 507

Query: 538 --------CHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTL 580
                      L  +   L    R +  L  L   Q ++   +LN LL  L
Sbjct: 508 KTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDL 558


>gi|9910266 kinesin family member 15 [Homo sapiens]
          Length = 1388

 Score =  220 bits (561), Expect = 4e-57
 Identities = 172/492 (34%), Positives = 250/492 (50%), Gaps = 49/492 (9%)

Query: 74  FVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP--- 130
           F FD V D  +TQ  VF    K I+ S ++GYN T+ AYG TG+GKT TM+G ++     
Sbjct: 70  FTFDHVADVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFS 129

Query: 131 ----GVMYLTMLHLYKCMDEIKEE----KICSTAVSYLEVYNEQIRDLLVN-SGPLAVRE 181
               GV+  +  +L+  +D  KE+    K      S++E+YNEQI DLL + S  L +RE
Sbjct: 130 HNLRGVIPRSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDSASAGLYLRE 189

Query: 182 DTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDK 241
             +KGV V G       S+ E   +L  G +NR    T MN  SSRSHAVF I +   +K
Sbjct: 190 HIKKGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEK 249

Query: 242 TASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALAD-SKR 300
           +  I  N+R + ++L+DLAGSER   + A+G R  E  NINRSL  LG VI AL D    
Sbjct: 250 SNEI-VNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNG 308

Query: 301 KNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLK 360
           K +H+ YR+SKLT LL+DSLGGN +T +IA V P S  + +T +TL +A RAK IK+   
Sbjct: 309 KQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAV 368

Query: 361 SNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQAKLMISNPQEKEIE 420
            N     N         ++ +AE+  LKE+L     + A      ++ L     +   +E
Sbjct: 369 VNEDTQGN--------VSQLQAEVKRLKEQL----AELASGQTPPESFLTRDKKKTNYME 416

Query: 421 RFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKATGKR 480
            FQE +   F+  E+ ++  ++    L++  LK     Q +K I +   ED++ +     
Sbjct: 417 YFQEAM-LFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMI-VKFREDQIIR----- 469

Query: 481 DHRLAMLKTRRSYLEKRREEELKQF--DENTNWLHRVEKEMGLL-SQNGHIPKELKKDLH 537
                        LEK  +E    F  +E    L  +  E+  L  Q  H P+  K  + 
Sbjct: 470 -------------LEKLHKESRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAME 516

Query: 538 CHHLHLQNKDLK 549
            H L  +N+ L+
Sbjct: 517 NHSLREENRRLR 528



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 49/250 (19%), Positives = 103/250 (41%), Gaps = 31/250 (12%)

Query: 282  NRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDD 341
            N  +  L +V+++ A+  +  +  P+  + L +LL+       Q I     S +S+ +  
Sbjct: 1122 NFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQE----QEIEDGRASKTSLEH-- 1175

Query: 342  TYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEI---LLLKEKLKAYEEQK 398
                +   N  +++K++    +L +   + +   +  E +  I    LL+ +L   + QK
Sbjct: 1176 ---LVTKLNEDREVKNA---EILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQK 1229

Query: 399  AFTNENDQAKLMISNPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQ 458
              +++N      + N QE+ I             +E + +  +  EML  + +L+     
Sbjct: 1230 ENSDQNHPDNQQLKNEQEESI-------------KERLAKSKIVEEMLKMKADLEEVQSA 1276

Query: 459  QCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKE 518
              +K++E +   D+VE+            +  RS LE+  EE  +   E      +VE  
Sbjct: 1277 LYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVE-- 1334

Query: 519  MGLLSQNGHI 528
              L  +NG +
Sbjct: 1335 -CLAEENGKL 1343


>gi|45446749 kinesin family member 5A [Homo sapiens]
          Length = 1032

 Score =  218 bits (556), Expect = 2e-56
 Identities = 185/577 (32%), Positives = 281/577 (48%), Gaps = 85/577 (14%)

Query: 12  MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
           +KV+ R RP N  E   G        DK I +F   Q + S   G K             
Sbjct: 10  IKVLCRFRPLNQAEILRG--------DKFIPIF---QGDDSVVIGGKP------------ 46

Query: 72  LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPG 131
             +VFD VF   +TQ +V+      I++  L GYN T+ AYG T +GKTHTM G   +P 
Sbjct: 47  --YVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQ 104

Query: 132 VMYLT-------MLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL-VNSGPLAVREDT 183
           +M +          H+Y  MDE  E  I    VSY E+Y ++IRDLL V    L+V ED 
Sbjct: 105 LMGIIPRIARDIFNHIYS-MDENLEFHI---KVSYFEIYLDKIRDLLDVTKTNLSVHEDK 160

Query: 184 QKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTA 243
            +   V G T     S EEIL ++D G  NR    T+MN  SSRSH++F I ++Q++   
Sbjct: 161 NRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMET 220

Query: 244 SINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQ 303
               +    K+ L+DLAGSE+ S +GA+G    E  NIN+SL ALGNVI+ALA+  +   
Sbjct: 221 EQKLS---GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKS-- 275

Query: 304 HIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNV 363
           ++PYR+SK+TR+L+DSLGGNC+T M    SPSS    +T +TL +  RAK IK++   N+
Sbjct: 276 YVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNL 335

Query: 364 -LNVNNHITQYVKICNEQKAE---ILLLKEKLKAYE-------------EQKAF------ 400
            L       +Y K   + KA+   I  L+ +L  +              E+ A       
Sbjct: 336 ELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCE 395

Query: 401 -TNENDQAKLMI---SNPQEKEIERFQEILNCLFQNREEIRQ-----EYLKLEMLLKENE 451
            T  ND + +++      ++K  E  + +   L    +EI Q     E LK +ML +E  
Sbjct: 396 ETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEEL 455

Query: 452 LKS-------FYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEE--- 501
           L S         ++  H Q E   ++D+V++     +        +   +E++ ++    
Sbjct: 456 LVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLL 515

Query: 502 LKQFDENTNWLHRVEKEMGLLSQ-NGHIPKELKKDLH 537
           + +  +    +  +E E+  L + +GH  K + + L+
Sbjct: 516 VDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLN 552


>gi|4758648 kinesin family member 5B [Homo sapiens]
          Length = 963

 Score =  216 bits (549), Expect = 1e-55
 Identities = 167/501 (33%), Positives = 255/501 (50%), Gaps = 79/501 (15%)

Query: 11  HMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNK 70
           ++KV+ R RP N  E   G        DK+I          + F G+ T    VI  +  
Sbjct: 8   NIKVMCRFRPLNESEVNRG--------DKYI----------AKFQGEDTV---VIASK-- 44

Query: 71  DLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP 130
              + FD VF  +++Q +V+    K I++  L GYN T+ AYG T +GKTHTM G   +P
Sbjct: 45  --PYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP 102

Query: 131 ---GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL-VNSGPLAVREDTQKG 186
              G++   +  ++  +  + E       VSY E+Y ++IRDLL V+   L+V ED  + 
Sbjct: 103 EGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRV 162

Query: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
             V G T     S +E++  +D G  NR    T+MN  SSRSH++F I ++Q++      
Sbjct: 163 PYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQK 222

Query: 247 QNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIP 306
            +    K+ L+DLAGSE+ S +GA+G    E  NIN+SL ALGNVI+ALA+    + ++P
Sbjct: 223 LS---GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG---STYVP 276

Query: 307 YRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNV 366
           YR+SK+TR+L+DSLGGNC+T ++   SPSS    +T +TL +  RAK IK+++    +NV
Sbjct: 277 YRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTV---CVNV 333

Query: 367 NNHITQYVKICNEQKAEILLL-----------------------------KEKLKAYEEQ 397
                Q+ K   ++K +  +L                             K  L+A+   
Sbjct: 334 ELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVD 393

Query: 398 KAFTNENDQ---AKLMISNPQEKEIERFQEILNCLFQ----NREEIRQ-----EYLKLEM 445
           K  T  ND+   A  +I N  + E  + +E +  L++      EEI Q     E LK +M
Sbjct: 394 KDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQM 453

Query: 446 LLKENELKSFYQQQCHKQIEM 466
           L +E  L S  + Q + Q E+
Sbjct: 454 LDQEELLASTRRDQDNMQAEL 474


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,276,762
Number of Sequences: 37866
Number of extensions: 1536272
Number of successful extensions: 7554
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 359
Number of HSP's that attempted gapping in prelim test: 6554
Number of HSP's gapped (non-prelim): 1073
length of query: 898
length of database: 18,247,518
effective HSP length: 111
effective length of query: 787
effective length of database: 14,044,392
effective search space: 11052936504
effective search space used: 11052936504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.