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Search of human proteins with 148596988
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3
[Homo sapiens]
(650 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [... 1309 0.0
gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [... 1269 0.0
gi|32171215 CREB regulated transcription coactivator 2 [Homo sap... 338 7e-93
gi|110431352 transducer of regulated CREB protein 3 isoform b [H... 278 1e-74
gi|110431354 transducer of regulated CREB protein 3 isoform a [H... 277 2e-74
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 81 3e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 72 2e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 68 2e-11
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 67 5e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 67 7e-11
gi|32307177 forkhead box G1 [Homo sapiens] 66 9e-11
gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 65 1e-10
gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 65 1e-10
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 65 2e-10
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 65 2e-10
gi|153792074 proline rich 12 [Homo sapiens] 65 2e-10
gi|157168329 formin 1 [Homo sapiens] 64 4e-10
gi|210032580 SET domain containing 1B [Homo sapiens] 64 6e-10
gi|160707881 formin 2 [Homo sapiens] 63 1e-09
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 63 1e-09
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 63 1e-09
gi|190343021 Sec24-related protein D [Homo sapiens] 63 1e-09
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 62 1e-09
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 62 1e-09
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 62 1e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is... 62 1e-09
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 62 1e-09
gi|27262645 ataxin 2 related protein isoform B [Homo sapiens] 62 1e-09
gi|27262653 ataxin 2 related protein isoform E [Homo sapiens] 62 1e-09
gi|27262649 ataxin 2 related protein isoform C [Homo sapiens] 62 1e-09
>gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3
[Homo sapiens]
Length = 650
Score = 1309 bits (3388), Expect = 0.0
Identities = 650/650 (100%), Positives = 650/650 (100%)
Query: 1 MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQY 60
MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQY
Sbjct: 1 MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQY 60
Query: 61 YGGSLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQSSGLDTSRTTRHHGLVDRV 120
YGGSLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQSSGLDTSRTTRHHGLVDRV
Sbjct: 61 YGGSLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQSSGLDTSRTTRHHGLVDRV 120
Query: 121 YRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQ 180
YRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQ
Sbjct: 121 YRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQ 180
Query: 181 PESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIF 240
PESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIF
Sbjct: 181 PESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIF 240
Query: 241 PSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAAN 300
PSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAAN
Sbjct: 241 PSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAAN 300
Query: 301 LTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDAL 360
LTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDAL
Sbjct: 301 LTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDAL 360
Query: 361 SLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASL 420
SLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASL
Sbjct: 361 SLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASL 420
Query: 421 TRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVS 480
TRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVS
Sbjct: 421 TRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVS 480
Query: 481 NQGFSPGSSPQHTSTLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPG 540
NQGFSPGSSPQHTSTLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPG
Sbjct: 481 NQGFSPGSSPQHTSTLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPG 540
Query: 541 STLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGV 600
STLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGV
Sbjct: 541 STLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGV 600
Query: 601 GDVSFDSDSQFPLDELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL 650
GDVSFDSDSQFPLDELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL
Sbjct: 601 GDVSFDSDSQFPLDELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL 650
>gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1
[Homo sapiens]
Length = 634
Score = 1269 bits (3284), Expect = 0.0
Identities = 634/650 (97%), Positives = 634/650 (97%), Gaps = 16/650 (2%)
Query: 1 MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQY 60
MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQY
Sbjct: 1 MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQY 60
Query: 61 YGGSLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQSSGLDTSRTTRHHGLVDRV 120
YGGSLPNVNQIGSGTMDLPFQ TPFQSSGLDTSRTTRHHGLVDRV
Sbjct: 61 YGGSLPNVNQIGSGTMDLPFQ----------------TPFQSSGLDTSRTTRHHGLVDRV 104
Query: 121 YRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQ 180
YRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQ
Sbjct: 105 YRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQ 164
Query: 181 PESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIF 240
PESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIF
Sbjct: 165 PESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIF 224
Query: 241 PSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAAN 300
PSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAAN
Sbjct: 225 PSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAAN 284
Query: 301 LTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDAL 360
LTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDAL
Sbjct: 285 LTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDAL 344
Query: 361 SLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASL 420
SLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASL
Sbjct: 345 SLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASL 404
Query: 421 TRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVS 480
TRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVS
Sbjct: 405 TRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVS 464
Query: 481 NQGFSPGSSPQHTSTLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPG 540
NQGFSPGSSPQHTSTLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPG
Sbjct: 465 NQGFSPGSSPQHTSTLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPG 524
Query: 541 STLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGV 600
STLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGV
Sbjct: 525 STLNYSQAAMMGLTGSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGV 584
Query: 601 GDVSFDSDSQFPLDELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL 650
GDVSFDSDSQFPLDELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL
Sbjct: 585 GDVSFDSDSQFPLDELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL 634
>gi|32171215 CREB regulated transcription coactivator 2 [Homo
sapiens]
Length = 693
Score = 338 bits (868), Expect = 7e-93
Identities = 280/727 (38%), Positives = 360/727 (49%), Gaps = 126/727 (17%)
Query: 2 ATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYY 61
A+++NPRKFSEKIAL Q+QAEETAAFEEVM D+ TR LQ QK L+L +R +Y
Sbjct: 14 ASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTR---LQAQK---LRLAYTRSSHY 67
Query: 62 GGSLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQS---SGLDTSRTTRHHGLVD 118
GGSLPNVNQIGSG L FQS S LD+SR+TRHHGLV+
Sbjct: 68 GGSLPNVNQIGSG----------------------LAEFQSPLHSPLDSSRSTRHHGLVE 105
Query: 119 RVYRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRT------------- 165
RV R+ R+ SP RR + R DS PY YLSPP ++SWRRT
Sbjct: 106 RVQRDPRRMVSPLRR------YTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQL 159
Query: 166 ----------NSDSALHQSTMTPTQPESFSSGSQD--VHQKRVLLLT------VPGMEET 207
+SDSALH S M P+ +++ + + +R +L VP +EE
Sbjct: 160 FRLPSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEEN 219
Query: 208 TSEADKNLSKQAWDTKK---TGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPD 264
+ DK+L K WD KK + SRP+SCEVPGINIFPS DQ ++P NTGGSLPD
Sbjct: 220 LLD-DKHLLKP-WDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPD 277
Query: 265 LTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIG---GAGQGMSTPG-SSP 320
LTN+HFP PLPTPLDPEE +P+LS +ST NL +THLGI G G G PG SP
Sbjct: 278 LTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSP 337
Query: 321 QHRPAGVSPL-------SLSTEARRQQAS---PTLSPLSPITQAVAMDALSLEQQLPYAF 370
P+ S L SLS+ + Q S P+L P S + + V L
Sbjct: 338 LSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSL-PASSLARHVLPTTSLGHPSLSAPA 396
Query: 371 FTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLA 430
+ + S P P PAS P P V L P L A R Q P
Sbjct: 397 LSSSSSSSSTSSPVLGAPSYPAS--TPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQ 454
Query: 431 VTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGF------ 484
+ P+ P G P +++ L Y S SP+ PT P + +
Sbjct: 455 FS-PTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYS--SPSLVLPTQPHTPKSLQQPGLP 511
Query: 485 --------SPGSSPQHTSTLGSVF--GDAYYEQQMAARQANALS-HQLEQFNMMENAISS 533
S G P S G+ + G + + QQ R + + LEQF+ ME+ +S
Sbjct: 512 SQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFS-MESPSAS 570
Query: 534 SSLYSPGSTLNYSQAAMMGLTGSHGSLPD-----SQQLGYAS-HSGIPNIILTVTGESPP 587
L PG + +G G G D Q L + S H PNIIL TG+S P
Sbjct: 571 LVLDPPGFS---EGPGFLGGEGPMGGPQDPHTFNHQNLTHCSRHGSGPNIIL--TGDSSP 625
Query: 588 SLSKELTSSLAGVGDVSFDSDS-QFPL---DELKIDPLTLDGLHMLNDPDMVLADPATED 643
SKE+ ++LAGV + + L DEL+++PL L+GL+ML+DP +L DPA E+
Sbjct: 626 GFSKEIAAALAGVPGFEVSAAGLELGLGLEDELRMEPLGLEGLNMLSDPCALLPDPAVEE 685
Query: 644 TFRMDRL 650
+FR DRL
Sbjct: 686 SFRSDRL 692
>gi|110431352 transducer of regulated CREB protein 3 isoform b [Homo
sapiens]
Length = 618
Score = 278 bits (710), Expect = 1e-74
Identities = 241/697 (34%), Positives = 320/697 (45%), Gaps = 137/697 (19%)
Query: 4 SNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYYGG 63
S NPRKFSEKIALH Q+QAEET AFE++M DL+L+R +Q QK Q L+L QY+GG
Sbjct: 9 SANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSR---VQFQKLQQLRLT----QYHGG 61
Query: 64 SLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQSSGLDTSRTTRHHGLVDRVYRE 123
SLPNV+Q+ S + FQPS F + D R TRHHGLV+R
Sbjct: 62 SLPNVSQLRSSASE--FQPS----------------FHQA--DNVRGTRHHGLVERP--S 99
Query: 124 RGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSW--------------------- 162
R R HRR S DK GRQ D +G Y S P D SW
Sbjct: 100 RNRFHPLHRR--SGDKPGRQFDGSAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSAL 157
Query: 163 RRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVL------------LLTVPG--MEETT 208
RTNSDSALH S ++ + + G Q + + + PG EE
Sbjct: 158 NRTNSDSALHTSALSTKPQDPYGGGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENL 217
Query: 209 SEADKNLSKQAWDTKKTGS---RPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDL 265
K L KQ W+TK+ S RP+SC+V G N FP Q + T NTGGSLPDL
Sbjct: 218 LNVPKPLPKQLWETKEIQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDL 277
Query: 266 TNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQ-HRP 324
TN+H+ +PLP LD + F ++S +S N+ A +THLGI + G+ + S+P
Sbjct: 278 TNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGI-RSSSGLQSSRSNPSIQAT 336
Query: 325 AGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQ 384
+ LS S Q + P S L P + ++ SL + +QPP P
Sbjct: 337 LNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTT---NLSGPSRRRQPPVSPL 393
Query: 385 PPPPPPPA--------SQQPPPPPPPQAPVRLPPGGPL--LPSASLTRGPQPPPLAVTVP 434
P P A S P P P + + L LP+ + + PPP P
Sbjct: 394 TLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPP--YPAP 451
Query: 435 SSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTS 494
L Q + P P APA Q A S QS + QG S
Sbjct: 452 QELTQPLLQQPRAP-------EAPAQQ---PQAASSLPQSDFQLLPAQG----------S 491
Query: 495 TLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLT 554
+L + F D ++QQ + R A Q+ L GS
Sbjct: 492 SLTNFFPDVGFDQQ-SMRPGPAFPQQV-------------PLVQQGSR------------ 525
Query: 555 GSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPL- 613
L DS L + +S ++ T+ +S SL K+L S+LAG+ +VS + D+ FPL
Sbjct: 526 ----ELQDSFHLRPSPYSNCGSLPNTILPDSSTSLFKDLNSALAGLPEVSLNVDTPFPLE 581
Query: 614 DELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL 650
+EL+I+PL+LDGL+ML+D M L DP+ E+TFR DRL
Sbjct: 582 EELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 618
>gi|110431354 transducer of regulated CREB protein 3 isoform a [Homo
sapiens]
Length = 619
Score = 277 bits (709), Expect = 2e-74
Identities = 239/697 (34%), Positives = 317/697 (45%), Gaps = 136/697 (19%)
Query: 4 SNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYYGG 63
S NPRKFSEKIALH Q+QAEET AFE++M DL+L+R +Q QK Q L+L QY+GG
Sbjct: 9 SANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSR---VQFQKLQQLRLT----QYHGG 61
Query: 64 SLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQSSGLDTSRTTRHHGLVDRVYRE 123
SLPNV+Q+ S + FQPS F + D R TRHHGLV+R
Sbjct: 62 SLPNVSQLRSSASE--FQPS----------------FHQA--DNVRGTRHHGLVERP--S 99
Query: 124 RGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSW--------------------- 162
R R HRR S DK GRQ D +G Y S P D SW
Sbjct: 100 RNRFHPLHRR--SGDKPGRQFDGSAFGANYSSQPLDESWPRQQPPWKDEKHPGFRLTSAL 157
Query: 163 RRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRVL------------LLTVPG--MEETT 208
RTNSDSALH S ++ + + G Q + + + PG EE
Sbjct: 158 NRTNSDSALHTSALSTKPQDPYGGGGQSAWPAPYMGFCDGENNGHGEVASFPGPLKEENL 217
Query: 209 SEADKNLSKQAWDTKKTGS---RPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDL 265
K L KQ W+TK+ S RP+SC+V G N FP Q + T NTGGSLPDL
Sbjct: 218 LNVPKPLPKQLWETKEIQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDL 277
Query: 266 TNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQ-HRP 324
TN+H+ +PLP LD + F ++S +S N+ A +THLGI + G+ + S+P
Sbjct: 278 TNLHYSTPLPASLDTTDHHFGSMSVGNSVNNIPAAMTHLGI-RSSSGLQSSRSNPSIQAT 336
Query: 325 AGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQ 384
+ LS S Q + P S L P + ++ SL + +QPP P
Sbjct: 337 LNKTVLSSSLNNHPQTSVPNASALHPSLRLFSLSNPSLSTT---NLSGPSRRRQPPVSPL 393
Query: 385 PPPPPPPA--------SQQPPPPPPPQAPVRLPPGGPL--LPSASLTRGPQPPPLAVTVP 434
P P A S P P P + + L LP+ + + PPP P
Sbjct: 394 TLSPGPEAHQGFSRQLSSTSPLAPYPTSQMVSSDRSQLSFLPTEAQAQVSPPPP--YPAP 451
Query: 435 SSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTS 494
L Q + P P APA Q A S QS + QG S
Sbjct: 452 QELTQPLLQQPRAP-------EAPAQQ---PQAASSLPQSDFQLLPAQG----------S 491
Query: 495 TLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLT 554
+L + F D ++QQ + R A Q+ + S P
Sbjct: 492 SLTNFFPDVGFDQQ-SMRPGPAFPQQVPLVQQGSRELQDSFHLRPSP------------- 537
Query: 555 GSHGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPL- 613
Y++ +PN IL +S SL K+L S+LAG+ +VS + D+ FPL
Sbjct: 538 -------------YSNCGSLPNTIL--PEDSSTSLFKDLNSALAGLPEVSLNVDTPFPLE 582
Query: 614 DELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL 650
+EL+I+PL+LDGL+ML+D M L DP+ E+TFR DRL
Sbjct: 583 EELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 619
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 81.3 bits (199), Expect = 3e-15
Identities = 105/385 (27%), Positives = 139/385 (36%), Gaps = 56/385 (14%)
Query: 129 SPHRRPLSVDKHGRQADSCPYG-------TMYLSPPADTSWRRTNSDSALHQSTMTPTQP 181
SP + S+ R A + P ++ SPP TS S + S +T
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLS---SPLTIHPL 489
Query: 182 ESFSSGSQDVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIFP 241
++ SS + Q + L +P +E +S A +L + P S P + P
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ----------TPPASLTTPPLENLP 539
Query: 242 S-ADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAAN 300
S A TA P T P L P+P P P T P + SS
Sbjct: 540 SLAPPPLQTASAPLT------TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 301 LTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSP-LSPITQAVAMDA 359
QG+ +P SP P +P L+ + SP SP LSP+
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653
Query: 360 LSLEQQLPYAFFTQAGSQQPPPQP------QPPPPPP------PASQQPP--PPPPPQAP 405
+L L A F+ PPP P PP PP P SQ PP PP Q P
Sbjct: 654 NALAVHLLQAPFS------PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707
Query: 406 VRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRT 465
P P+ PSA T PQ PP P +P SPP +P P L
Sbjct: 708 PSPPASPPMSPSA--TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL----- 760
Query: 466 SAGSPANQSPTSPVSNQGFSPGSSP 490
+P Q P SP ++ SP + P
Sbjct: 761 -LAAPPLQVPPSPPASLPMSPLAKP 784
Score = 61.6 bits (148), Expect = 2e-09
Identities = 87/302 (28%), Positives = 123/302 (40%), Gaps = 46/302 (15%)
Query: 223 KKTGSRPKSCEVPGINIFPSADQENTTALIPATHNTG---GSLPDLTNIHFPSPLPT--P 277
++T +R K+ E P + + + +T+ P T + S T + P P P+ P
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198
Query: 278 LDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGS-------SPQHRPAGVSPL 330
P E ++SS+S + AG G+ P S +P PA P
Sbjct: 199 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258
Query: 331 SLSTE---ARRQQASPT-LSPLSP--IT--QAVAMDALSLEQQLPYAFFTQAGSQ-QPPP 381
+ T A Q P L L P +T + A AL P A + +G++ +P P
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318
Query: 382 QPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSP 441
P P PA+ PP PP P+ L P P P SL P PP T PS P S
Sbjct: 319 PPDNAATPLPATL--PPSPPLATPLPLAPPSPSAP-PSLQTLPSPP---ATPPSQAPPSM 372
Query: 442 PENPGQPSMGIDIASAPALQ-----QYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTSTL 496
P Q + P+LQ Q S SP+ Q+P SP++ SS Q T++L
Sbjct: 373 TTPPMQ--------APPSLQTIPPIQVPHSLTSPSLQAPPSPLAL------SSLQATTSL 418
Query: 497 GS 498
GS
Sbjct: 419 GS 420
Score = 60.8 bits (146), Expect = 4e-09
Identities = 69/246 (28%), Positives = 96/246 (39%), Gaps = 33/246 (13%)
Query: 273 PLPTPLDPEEPTFPALSSSSSTGNLAA-NLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLS 331
P+ P P P P +S S++ + A +L + ++P SP P +P
Sbjct: 672 PVQAPFSP--PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729
Query: 332 LSTEARRQQASPTLSP-LSP-------ITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQP 383
L+ + SP SP +SP + +A L + P S P
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP-------ASLPMSPLA 782
Query: 384 QPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASL------TRGPQPPPLAVTVPSSL 437
+PPP PPA PP P P P P PSASL T PQ PP+ +
Sbjct: 783 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 842
Query: 438 PQSPPENP------GQPSMGIDIA-SAPALQ-QYRTSAGSPANQSPTSPVSNQGFSPGSS 489
P SPP +P P+ G D + S P L P ++SP+S +S + G S
Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA-GHS 901
Query: 490 PQHTST 495
TST
Sbjct: 902 SSATST 907
Score = 48.1 bits (113), Expect = 2e-05
Identities = 55/194 (28%), Positives = 71/194 (36%), Gaps = 31/194 (15%)
Query: 271 PSPLPTP---LDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGV 327
P PL P + P P P +S S++ L A + P S P P +
Sbjct: 727 PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL------AAPPLQVPPSPPASLP--M 778
Query: 328 SPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPP 387
SPL+ QA P L+ +P QA+ S Q P F+ + S P PPP
Sbjct: 779 SPLAKPPP----QAPPALA--TPPLQALPSPPASFPGQAP---FSPSASLPMSPLATPPP 829
Query: 388 PPPPASQQPPPPPPPQAPVRLPPGGPLL--PSASLTRGPQP----PPLAVTVPSSLPQSP 441
PP P PP PP P L P T GP P L + + P P
Sbjct: 830 QAPPVLAAPLLQVPPS-----PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884
Query: 442 PENPGQPSMGIDIA 455
+P G D+A
Sbjct: 885 SRSPSSTLSGPDLA 898
Score = 40.8 bits (94), Expect = 0.004
Identities = 58/255 (22%), Positives = 87/255 (34%), Gaps = 37/255 (14%)
Query: 236 GINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTG 295
G P +N +PAT LP + P PL P P+ L S +T
Sbjct: 311 GTKARPVPPPDNAATPLPAT------LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364
Query: 296 NLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSL--STEARRQQASPTLSPLSPITQ 353
A M+TP + P+ + S + QA P+ LS +
Sbjct: 365 P----------SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQA 414
Query: 354 AVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGP 413
++ + +L Q ++F T + Q P P PP P+ LP P
Sbjct: 415 TTSLGSPTL--QATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA----PLSLPASPP 468
Query: 414 LLPSASLTRGPQPPPLAV-------TVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTS 466
L S S P PL + ++ S PQ+P + P + + AP S
Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP------PS 522
Query: 467 AGSPANQSPTSPVSN 481
+P T P+ N
Sbjct: 523 LQTPPASLTTPPLEN 537
Score = 39.7 bits (91), Expect = 0.009
Identities = 36/125 (28%), Positives = 49/125 (39%), Gaps = 17/125 (13%)
Query: 373 QAGSQQPPPQPQPP---PPPPPASQQPPPPPPPQAPVRLPPGG-----PLLPSASLTRGP 424
+AG+ P + P P PP S +PPPP P A L G PL A G
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG- 67
Query: 425 QPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGF 484
T+P S P++ P S + PA R PA + PVS+ G
Sbjct: 68 ------ATIPESAPRAGPTRSAGTSSRNPASRPPA--SGRGERAPPAKNTSPGPVSSPGR 119
Query: 485 SPGSS 489
+ G++
Sbjct: 120 ASGTT 124
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 71.6 bits (174), Expect = 2e-12
Identities = 86/330 (26%), Positives = 119/330 (36%), Gaps = 64/330 (19%)
Query: 223 KKTGSRPKSCEVPGINIFPSADQENTTALIPATHNTG---GSLPDLTNIHFPSPLPT--P 277
++T +R K+ E P + + + +T+ P T + S T + P P P+ P
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198
Query: 278 LDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGS-------SPQHRPAGVSPL 330
P E ++SS+S + AG G+ P S +P PA P
Sbjct: 199 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258
Query: 331 SLSTEAR-----------------------RQQASPTLSPLSPITQAVAMDALSLEQQLP 367
+ T R+ A+P L PLS A + +L+ Q P
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318
Query: 368 YAFFTQAGS-----QQPPPQPQPPPPP--PPASQ---QPPPPPPPQAPVRLP-------- 409
S Q P P PP P PP+ Q PP PP QA L
Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 378
Query: 410 ---PGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAP------AL 460
P PL P A T PQ PP P P SPP +P + AP L
Sbjct: 379 SFLPSPPLSPLA--TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436
Query: 461 QQYRTSAGSPANQSPTSPVSNQGFSPGSSP 490
Q + SP Q+P SP ++ SP ++P
Sbjct: 437 QAPFSPPPSPPVQAPFSPPASPPVSPSATP 466
Score = 66.2 bits (160), Expect = 9e-11
Identities = 89/309 (28%), Positives = 115/309 (37%), Gaps = 55/309 (17%)
Query: 229 PKSCEVPGINIFPSAD----QENTTAL----IPATHNTGGSLPDLTNIHFPSPLPTPL-- 278
P P + PS + TT+L + ATH+ S P L+ + P P P
Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS-PPLSPLATPPPQAPPALA 401
Query: 279 ------DPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSL 332
P P P LS ++ A N L + S P S P P P S
Sbjct: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNA--LAVHLLQAPFSPPPSPPVQAPFS-PPAS- 457
Query: 333 STEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPP------ 386
SP+ +P S ++A L + P A + S PPPQ PP
Sbjct: 458 ------PPVSPSATPPSQAPPSLAAPPLQVPPSPP-ASPPMSPSATPPPQAPPPLAAPPL 510
Query: 387 ----PPP--PPASQQPPPPPPPQAPVRLPPGGPLLPSASL------TRGPQPPPLAVTVP 434
PPP PPA PP P P P P PSASL T PQ PP+
Sbjct: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 570
Query: 435 SSLPQSPPENP------GQPSMGIDIA-SAPALQ-QYRTSAGSPANQSPTSPVSNQGFSP 486
+P SPP +P P+ G D + S P L P ++SP+S +S +
Sbjct: 571 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA- 629
Query: 487 GSSPQHTST 495
G S TST
Sbjct: 630 GHSSSATST 638
Score = 39.7 bits (91), Expect = 0.009
Identities = 36/125 (28%), Positives = 49/125 (39%), Gaps = 17/125 (13%)
Query: 373 QAGSQQPPPQPQPP---PPPPPASQQPPPPPPPQAPVRLPPGG-----PLLPSASLTRGP 424
+AG+ P + P P PP S +PPPP P A L G PL A G
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG- 67
Query: 425 QPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGF 484
T+P S P++ P S + PA R PA + PVS+ G
Sbjct: 68 ------ATIPESAPRAGPTRSAGTSSRNPASRPPA--SGRGERAPPAKNTSPGPVSSPGR 119
Query: 485 SPGSS 489
+ G++
Sbjct: 120 ASGTT 124
Score = 37.4 bits (85), Expect = 0.044
Identities = 81/372 (21%), Positives = 123/372 (33%), Gaps = 83/372 (22%)
Query: 273 PLPTPLDPEEPTFPALSSSSSTGNLAA-NLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLS 331
P+ P P P P +S S++ + A +L + ++P SP P +P
Sbjct: 447 PVQAPFSP--PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504
Query: 332 LSTEARRQQASPTLSP---LSPITQAVAMDALSLEQQLPY---AFFTQAGSQQPPPQPQP 385
L+ + P +P +P QA+ S Q P+ A + PPPQ P
Sbjct: 505 LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564
Query: 386 P--------PPPPPAS------QQPP--------------------PPPPPQAPVRLPPG 411
PP PPAS ++PP PPPPP
Sbjct: 565 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 624
Query: 412 GPLLP--SASLTRGPQ---------------PPPLAVTVPSSLPQSPPENPGQPSMGIDI 454
GP L S+S T P+ PP + + P + P P
Sbjct: 625 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 684
Query: 455 ASAPALQQYRTSAGS------------PANQSPTSPVSNQGFSPGSSPQHTSTLGSVFGD 502
AP T GS P + +P + G SPG+S +
Sbjct: 685 PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS 744
Query: 503 AYYEQQ-------MAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTG 555
+ +Q + A QA+ + H L + ++ A ++ GS A G+TG
Sbjct: 745 SRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAG----GSGGGPGGAEGGGVTG 800
Query: 556 SHGSLPDSQQLG 567
+ +LG
Sbjct: 801 GARAALSDAELG 812
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 68.2 bits (165), Expect = 2e-11
Identities = 92/323 (28%), Positives = 119/323 (36%), Gaps = 55/323 (17%)
Query: 215 LSKQAWDTKKTGSRPKSCEVPGINIFPSAD----QENTTAL----IPATHNTGGSLPDLT 266
LS T + P P + PS + TT+L + ATH+ S P L+
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS-PPLS 348
Query: 267 NIHFPSPLPTPL--------DPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGS 318
+ P P P P P P LS ++ A N L + S P S
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA--LAVHLLQAPFSPPPS 406
Query: 319 SPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQ 378
P P P S SP+ +P S ++A L + P A + S
Sbjct: 407 PPVQAPFS-PPAS-------PPVSPSATPPSQAPPSLAAPPLQVPPSPP-ASPPMSPSAT 457
Query: 379 PPPQPQPP----------PPP--PPASQQPPPPPPPQAPVRLPPGGPLLPSASL------ 420
PPPQ PP PPP PPA PP P P P P PSASL
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517
Query: 421 TRGPQPPPLAVTVPSSLPQSPPENP------GQPSMGIDIA-SAPALQ-QYRTSAGSPAN 472
T PQ PP+ +P SPP +P P+ G D + S P L P +
Sbjct: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 577
Query: 473 QSPTSPVSNQGFSPGSSPQHTST 495
+SP+S +S + G S TST
Sbjct: 578 RSPSSTLSGPDLA-GHSSSATST 599
Score = 63.2 bits (152), Expect = 7e-10
Identities = 79/302 (26%), Positives = 114/302 (37%), Gaps = 38/302 (12%)
Query: 223 KKTGSRPKSCEVPGINIFPSADQENTTALIPATHNTG---GSLPDLTNIHFPSPLPT--P 277
++T +R K+ E P + + + +T+ P T + S T + P P P+ P
Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189
Query: 278 LDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEAR 337
P E ++SS+S + AG G+ P S + + +PLS +
Sbjct: 190 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS--RSLSSSATPLSSPARSG 247
Query: 338 RQQASPTLSPLSPIT-QAVAMDALSLEQQLPY------AFFTQAGSQQPPPQPQPPPPP- 389
+P P + + AL Q P A + S P P PP P
Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307
Query: 390 -PPASQ---QPPPPPPPQAPVRLPPGGP-------LLPSASLTRGPQPPPLA----VTVP 434
PP+ Q PP PP QA L G P LPS L+ PPP A P
Sbjct: 308 APPSLQTLPSPPATPPSQATTSL--GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 435 SSLPQSPPENPGQPSMGIDIASAP------ALQQYRTSAGSPANQSPTSPVSNQGFSPGS 488
P SPP +P + AP LQ + SP Q+P SP ++ SP +
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 425
Query: 489 SP 490
+P
Sbjct: 426 TP 427
Score = 38.1 bits (87), Expect = 0.026
Identities = 36/125 (28%), Positives = 49/125 (39%), Gaps = 26/125 (20%)
Query: 373 QAGSQQPPPQPQPP---PPPPPASQQPPPPPPPQAPVRLPPGG-----PLLPSASLTRGP 424
+AG+ P + P P PP S +PPPP P A L G PL A G
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG- 67
Query: 425 QPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGF 484
T+P S P++ P +P PA R PA + PVS+ G
Sbjct: 68 ------ATIPESAPRAGPTRTSRP---------PA--SGRGERAPPAKNTSPGPVSSPGR 110
Query: 485 SPGSS 489
+ G++
Sbjct: 111 ASGTT 115
Score = 37.4 bits (85), Expect = 0.044
Identities = 81/372 (21%), Positives = 123/372 (33%), Gaps = 83/372 (22%)
Query: 273 PLPTPLDPEEPTFPALSSSSSTGNLAA-NLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLS 331
P+ P P P P +S S++ + A +L + ++P SP P +P
Sbjct: 408 PVQAPFSP--PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 465
Query: 332 LSTEARRQQASPTLSP---LSPITQAVAMDALSLEQQLPY---AFFTQAGSQQPPPQPQP 385
L+ + P +P +P QA+ S Q P+ A + PPPQ P
Sbjct: 466 LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 525
Query: 386 P--------PPPPPAS------QQPP--------------------PPPPPQAPVRLPPG 411
PP PPAS ++PP PPPPP
Sbjct: 526 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 585
Query: 412 GPLLP--SASLTRGPQ---------------PPPLAVTVPSSLPQSPPENPGQPSMGIDI 454
GP L S+S T P+ PP + + P + P P
Sbjct: 586 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 645
Query: 455 ASAPALQQYRTSAGS------------PANQSPTSPVSNQGFSPGSSPQHTSTLGSVFGD 502
AP T GS P + +P + G SPG+S +
Sbjct: 646 PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS 705
Query: 503 AYYEQQ-------MAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTG 555
+ +Q + A QA+ + H L + ++ A ++ GS A G+TG
Sbjct: 706 SRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAG----GSGGGPGGAEGGGVTG 761
Query: 556 SHGSLPDSQQLG 567
+ +LG
Sbjct: 762 GARAALSDAELG 773
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 67.0 bits (162), Expect = 5e-11
Identities = 58/203 (28%), Positives = 73/203 (35%), Gaps = 40/203 (19%)
Query: 321 QHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPP 380
Q AGV+P E SP + +P T A A+ + TQ ++PP
Sbjct: 713 QQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPP 772
Query: 381 PQPQPPPP----PPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRG------------- 423
P PPPP PPP+ QPPPPPPP P L AS+ G
Sbjct: 773 PALPPPPPLAKFPPPSQPQPPPPPPPS------PASLLKSLASVLEGQKYCYRGTGAAVS 826
Query: 424 PQPPPLAVT-----VPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGS--------- 469
+P PL T PS PP + + G SA + Q+ TS G
Sbjct: 827 TRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGE 886
Query: 470 ---PANQSPTSPVSNQGFSPGSS 489
P +PT P P S
Sbjct: 887 EPVPGPMTPTQPPPPLSLPPARS 909
Score = 51.2 bits (121), Expect = 3e-06
Identities = 86/366 (23%), Positives = 124/366 (33%), Gaps = 84/366 (22%)
Query: 130 PHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQPESFSSGSQ 189
P RP + HG + P G S ++ +R+ DS++ + T P + S
Sbjct: 337 PGPRPPGAESHGCLPATRPPG----SDLRESRVQRSRMDSSVSPAATTACVPYAPSRP-- 390
Query: 190 DVHQKRVLLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIFPSADQENTT 249
PG+ TT+ + + S +T G P PGI P AD T
Sbjct: 391 ------------PGLPGTTTSSSSSSSS---NTGLRGVEPN----PGI---PGADHYQTP 428
Query: 250 ALIPATHNTGG--------------------SLPDLTNIHFPSPLPTPLDPEEPTF---- 285
AL + H G SLP + P P P L P P
Sbjct: 429 ALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKG 488
Query: 286 PALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTL 345
PA ++ G + L L G G P P HR + P + Q +
Sbjct: 489 PACRAAREDGEI---LEELFFGTEGPPRPAPPPLP-HREGFLGPPASRFSVGTQDSHTPP 544
Query: 346 SPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAP 405
+P +P T + ++ S P P PPPP ++ P P P +P
Sbjct: 545 TPPTPTTSSSNSNSGS--------------HSSSPAGPVSFPPPPYLARSIDPLPRPPSP 590
Query: 406 VRLPPGGPLLPSASLTRGPQPP-------------PLAVTVPSSLPQSPPENPGQPSMGI 452
+ P PL+P +L P PP P + S P++P PG P +
Sbjct: 591 AQNPQDPPLVP-LTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPL 649
Query: 453 DIASAP 458
A P
Sbjct: 650 SKAPQP 655
Score = 47.0 bits (110), Expect = 6e-05
Identities = 76/289 (26%), Positives = 98/289 (33%), Gaps = 70/289 (24%)
Query: 219 AWDTKKTGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPL 278
AW + P+S +PG S Q A +P +H + P +P P PL
Sbjct: 27 AWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPL 86
Query: 279 DPE-------------EPTFPAL------------SSSSST----------GNLAANLTH 303
+ EP P L S +T G+ A
Sbjct: 87 HGKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGPR 146
Query: 304 LGIGGAGQGMSTPGSSPQHRPAGVSPLS-----LSTEARRQQASPTLSPL------SPIT 352
+G Q + S QHR + PL L E +R + P P+
Sbjct: 147 IGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAEPPVV 206
Query: 353 QAVAMDALSL---EQQLPYAFFTQAG--SQQ---PPPQPQPPPPPPPASQQPPPPPPPQA 404
Q V ALS E+ L + G S+Q PP P PPPP PP PPPPPPP
Sbjct: 207 QPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPL- 265
Query: 405 PVRLPPGGPLLPSASLTRGPQPPPLAVTV------PSSLPQSPPENPGQ 447
PG P LT+ P L T+ P +PPE Q
Sbjct: 266 -----PGLATSPPFQLTK----PGLWSTLHGDAWGPERKGSAPPERQEQ 305
Score = 43.1 bits (100), Expect = 8e-04
Identities = 74/330 (22%), Positives = 106/330 (32%), Gaps = 83/330 (25%)
Query: 199 LTVPGMEETTSEADKNLSKQAWDTKKTGSRPK--------------------SCEVPGIN 238
LT PG+ T L AW ++ GS P + PG
Sbjct: 276 LTKPGLWST-------LHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHR 328
Query: 239 IFPSADQ--------ENTTALIPATHNTGGSLPDLT------NIHFPSPLPTPLDPEEPT 284
+ P+A + +PAT G L + + T P P+
Sbjct: 329 LVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPS 388
Query: 285 FPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPT 344
P ++T + +++ ++ G+ G PG+ PA L +S R
Sbjct: 389 RPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPA----LEVSHHGR------- 437
Query: 345 LSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPP--- 401
L P + L P+ PP PPPPP P +PPPPP
Sbjct: 438 ---LGPSAHSSRKPFLGAPAATPHLSL-------PPGPSSPPPPPCPRLLRPPPPPAWLK 487
Query: 402 -PQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQ-----SPPENPGQPSMGIDIA 455
P G L T GP P P LP PP + + S+G +
Sbjct: 488 GPACRAAREDGEILEELFFGTEGPPRP-----APPPLPHREGFLGPPAS--RFSVGTQDS 540
Query: 456 SAPALQQYRTSAGSPAN-----QSPTSPVS 480
P T++ S +N SP PVS
Sbjct: 541 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVS 570
Score = 39.3 bits (90), Expect = 0.011
Identities = 52/211 (24%), Positives = 77/211 (36%), Gaps = 26/211 (12%)
Query: 283 PTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQAS 342
PT P ++SSS N ++ + AG P P + + PL +
Sbjct: 544 PTPPTPTTSSSNSNSGSHSS----SPAGPVSFPP---PPYLARSIDPLPRPPSPAQNPQD 596
Query: 343 PTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQP----PPQPQPPPPPPPASQQPPP 398
P PL P+T A+ S Q F + S +P P P+ P PPP P
Sbjct: 597 P---PLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAP 653
Query: 399 PPPPQAPVRLPPGGPLL----PSASLTRGPQP------PPLAVTVPSSLPQSPPENPGQP 448
P P LP GP L P+ + +P P + L +S + Q
Sbjct: 654 QPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQ 713
Query: 449 SMGIDIASAPALQQYRTSAGS--PANQSPTS 477
+A P L++ S S P + +PT+
Sbjct: 714 QHEAGVAPQPPLKEPFASLQSPFPTDTAPTT 744
Score = 33.9 bits (76), Expect = 0.48
Identities = 41/141 (29%), Positives = 57/141 (40%), Gaps = 24/141 (17%)
Query: 271 PSPL---PTPLDPEEPTFPALSSSSSTGNLAANLT--HLGIGGAGQGMST-PGSSPQHR- 323
P PL P P P+ P P S +S +LA+ L G G +ST PG P +
Sbjct: 778 PPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQY 837
Query: 324 ----PAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQ-- 377
P+G + L ++ A Q SP S S + + P+A +AG +
Sbjct: 838 SPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGG--------PWARERRAGEEPV 889
Query: 378 ---QPPPQPQPPPPPPPASQQ 395
P QP PP PPA +
Sbjct: 890 PGPMTPTQPPPPLSLPPARSE 910
Score = 33.1 bits (74), Expect = 0.82
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 12/61 (19%)
Query: 374 AGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRL-------PPG---GPLLPSASLTRG 423
A +PP P PP P P++Q P PP P + PPG +L SL+ G
Sbjct: 1041 ASKAKPPTAPAPPSAPAPSAQ--PTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEG 1098
Query: 424 P 424
P
Sbjct: 1099 P 1099
Score = 30.8 bits (68), Expect = 4.1
Identities = 24/59 (40%), Positives = 29/59 (49%), Gaps = 7/59 (11%)
Query: 393 SQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSL--PQSPPENPGQPS 449
S PP PPP A + PGG SAS+ + P P PL + SS P P PG P+
Sbjct: 29 SSCPPHPPPRSAWL---PGGRC--SASIGQPPLPAPLPPSHGSSSGHPSKPYYAPGAPT 82
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 66.6 bits (161), Expect = 7e-11
Identities = 69/242 (28%), Positives = 95/242 (39%), Gaps = 13/242 (5%)
Query: 313 MSTPGSSPQHRPAGVSPLSLSTEA----RRQQASPTLSPLSPITQAVAMDALSLEQQLPY 368
+S PG P PLS S E + P PLSPI A A ALS +L Y
Sbjct: 900 LSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEY 959
Query: 369 AFFTQAGSQQPPPQPQP----PPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGP 424
F + S P P P PPP + P P P + PG P+ P++ + P
Sbjct: 960 PFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEP 1019
Query: 425 QPPPLAVTVPSSL-PQ-SPPENPGQPSMGIDIAS--APALQQYRTSAGSPANQSPTSPVS 480
PP + + SL PQ SPP P++ + + S +P + S + ++ T VS
Sbjct: 1020 LPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVS 1079
Query: 481 NQGFSPGSSPQHTSTLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPG 540
+ P P TS L S GD A + S E ++ + S PG
Sbjct: 1080 -EPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPG 1138
Query: 541 ST 542
T
Sbjct: 1139 QT 1140
Score = 62.4 bits (150), Expect = 1e-09
Identities = 72/240 (30%), Positives = 90/240 (37%), Gaps = 51/240 (21%)
Query: 272 SPLP-TPLDP--EEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTP-GSSPQHRPAGV 327
SPL +PL P E P PAL + S A+ L S P SP P
Sbjct: 513 SPLEESPLSPPEESPPSPALETPLSPPPEASPL------------SPPFEESPLSPPPEE 560
Query: 328 SPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPP 387
P S EA R P SP+SP + M +L F + PPP+ P
Sbjct: 561 LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF--EESPLSPPPEESPLS 618
Query: 388 PPPPASQQPPPP-------PPPQAPVRLPPG----GPLLPSASLTRGPQPPPLAVTVPSS 436
PPP AS+ PPP PP ++P+ PP PL + L+ P+ PL+ P
Sbjct: 619 PPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS-PPPEE 677
Query: 437 LPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTSTL 496
P SPP + S P SPTSP SP S P S +
Sbjct: 678 SPTSPPPEASRLS-------------------PPPEDSPTSPPPED--SPASPPPEDSLM 716
Score = 60.1 bits (144), Expect = 6e-09
Identities = 55/188 (29%), Positives = 77/188 (40%), Gaps = 25/188 (13%)
Query: 316 PGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAG 375
P SP P SP S EA R P P SP+ +A+ + E L
Sbjct: 444 PEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL--------- 494
Query: 376 SQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPS 435
PPP+ P PPP +S P P ++P+ P P PS +L PPP A +
Sbjct: 495 --SPPPEESPLSPPPESS---PFSPLEESPLSPPEESP--PSPALETPLSPPPEASPLSP 547
Query: 436 SLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTST 495
+SP P + ++ ++P + R S P +SP SP + SP S P S
Sbjct: 548 PFEESPLSPPPE-----ELPTSPPPEASRLS--PPPEESPMSPPPEE--SPMSPPPEASR 598
Query: 496 LGSVFGDA 503
L F ++
Sbjct: 599 LFPPFEES 606
Score = 50.8 bits (120), Expect = 4e-06
Identities = 42/147 (28%), Positives = 62/147 (42%), Gaps = 20/147 (13%)
Query: 362 LEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPP------PPPQA-----PVRLPP 410
L +++P + PPP+ P PPP AS+ PPP P P+A P+ P
Sbjct: 434 LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESP 493
Query: 411 GGPLLPSASLTRGPQPPPLAVTVPSSLPQSPP-ENPGQPSMGIDIASAPALQQYRTSAGS 469
P + L+ P+ P + S P SPP E+P P++ ++ P +
Sbjct: 494 LSPPPEESPLSPPPESSPFSPLEES--PLSPPEESPPSPALETPLSPPPE----ASPLSP 547
Query: 470 PANQSPTSPVSNQGFSPGSSPQHTSTL 496
P +SP SP + P S P S L
Sbjct: 548 PFEESPLSPPPEE--LPTSPPPEASRL 572
Score = 50.1 bits (118), Expect = 7e-06
Identities = 69/243 (28%), Positives = 89/243 (36%), Gaps = 28/243 (11%)
Query: 271 PSP-LPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGG---AGQGMSTPGSSPQHRPAG 326
PSP L TPL P P LS L+ L A + P SP P
Sbjct: 528 PSPALETPLSPPPEASP-LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE 586
Query: 327 VSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPP 386
SP+S EA R SPLSP + + +L + PPP+ P
Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP--PEDSPMSPPPEESPM 644
Query: 387 PPPP--------PASQQPPPPPPPQAPVRLPP-GGPLLPSASLTRGPQPPPLAVT--VPS 435
PPP P + PPP ++P+ PP P P +R PP + T P
Sbjct: 645 SPPPEVSRLSPLPVVSRL-SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPE 703
Query: 436 SLPQSPPENPGQPSMGIDIASAPAL------QQYRTSAGSPANQSPTSP-VSNQGFSPGS 488
P SPP P M + + +P L Q S G + P P +S + P
Sbjct: 704 DSPASPP--PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL 761
Query: 489 SPQ 491
SPQ
Sbjct: 762 SPQ 764
Score = 46.2 bits (108), Expect = 9e-05
Identities = 45/151 (29%), Positives = 58/151 (38%), Gaps = 11/151 (7%)
Query: 347 PLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQP-PPPPPPASQQPPP------P 399
PL + + + LE QL A + PPP+ P PPP + PPP P
Sbjct: 411 PLQCEAKPLGKAGVQLEPQLE-APLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSP 469
Query: 400 PPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPA 459
PP + P P L S L P PP + S P+S P +P + S +P
Sbjct: 470 PPEELPAS-PLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPP 528
Query: 460 LQQYRTSAGSPANQSPTSPVSNQGFSPGSSP 490
T P SP SP + SP S P
Sbjct: 529 SPALETPLSPPPEASPLSPPFEE--SPLSPP 557
Score = 46.2 bits (108), Expect = 9e-05
Identities = 42/138 (30%), Positives = 55/138 (39%), Gaps = 13/138 (9%)
Query: 373 QAGSQQPP----PQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLL--PSASLTRGPQP 426
+AG Q P P + P PP + P PPP ++P PP L P L P P
Sbjct: 421 KAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLP 480
Query: 427 PPLAVTVP-SSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFS 485
L ++ P P SPP P + + S+P S SP +SP SP S
Sbjct: 481 EALHLSRPLEESPLSPP--PEESPLSPPPESSP-FSPLEESPLSPPEESPPSPALETPLS 537
Query: 486 PGSSPQHTSTLGSVFGDA 503
P P S L F ++
Sbjct: 538 P---PPEASPLSPPFEES 552
Score = 46.2 bits (108), Expect = 9e-05
Identities = 57/190 (30%), Positives = 74/190 (38%), Gaps = 42/190 (22%)
Query: 309 AGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQA---SPTLSPLSPITQAVAMDALSLEQQ 365
+GQG+ PG G+ P A+ Q +P L LSP Q + AL +++Q
Sbjct: 4181 SGQGL--PG-------VGIMPTVGQLRAQLQGVLAKNPQLRHLSP-QQQQQLQALLMQRQ 4230
Query: 366 LPYAFFTQAGSQQPPPQP--------------QP-----PPPPPPASQQPPPPPPPQAPV 406
L + QA Q PP Q QP P P Q+ P PQ P
Sbjct: 4231 LQQS---QAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPP 4287
Query: 407 RLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTS 466
RLP P +L+ GP P+ T P S PQ P PS + + L T
Sbjct: 4288 RLPA-----PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPP--TH 4340
Query: 467 AGSPANQSPT 476
G+P Q PT
Sbjct: 4341 PGTPKPQGPT 4350
Score = 42.4 bits (98), Expect = 0.001
Identities = 66/267 (24%), Positives = 91/267 (34%), Gaps = 62/267 (23%)
Query: 280 PEEPTF------PALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLS 333
PEEP P LS + +L+ L + + P SP +SP
Sbjct: 774 PEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTE---EPHLSPVPEEPCLSPQPEE 830
Query: 334 TEARRQQASPTLSPL---SPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPP 390
+ Q P LSP S ++ + LS + P + Q P P+ P PPP
Sbjct: 831 SHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP----PEEPGQCPAPEELPLFPPP 886
Query: 391 -----------PASQQPPPPPPPQAPVRLP---PGGPLLPSASLTRGPQPPPLAVTVPSS 436
PA +P PP P LP G P L + P PPPL+ + ++
Sbjct: 887 GEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAA 946
Query: 437 LP-----------------QSPPENP-GQPSMGIDIASAPAL----------QQYRTSAG 468
P S PE+P P + I+ P S G
Sbjct: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG 1006
Query: 469 SPANQSPTSPVSNQGFSPGSSP--QHT 493
SP P SP+ + P SP QH+
Sbjct: 1007 SPV--GPASPILMEPLPPQCSPLLQHS 1031
Score = 41.6 bits (96), Expect = 0.002
Identities = 25/71 (35%), Positives = 28/71 (39%), Gaps = 4/71 (5%)
Query: 376 SQQPPPQPQPPPPPPPASQQPPPPPP----PQAPVRLPPGGPLLPSASLTRGPQPPPLAV 431
S PP +P PPP P S PP P P P+ PP LP AS +P P A
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRAR 4966
Query: 432 TVPSSLPQSPP 442
PP
Sbjct: 4967 PPEEGEDSRPP 4977
Score = 40.8 bits (94), Expect = 0.004
Identities = 51/195 (26%), Positives = 69/195 (35%), Gaps = 45/195 (23%)
Query: 302 THLGIGGAGQGMSTPG---SSPQHRPAGVSPLSLSTEARRQQASPT--LSPLSPITQAVA 356
THLG G + TP + R + V P S R Q+ P L+P P +
Sbjct: 2314 THLG----GLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIF 2369
Query: 357 MDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLP 416
+ PYA QPP P+P PPPP + PP P P P P
Sbjct: 2370 RPGSYTD---PYA--------QPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASP--Q 2416
Query: 417 SASLTRGP-QPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSP 475
S S ++ P P PL+ P +P R + P ++ P
Sbjct: 2417 SQSSSQSPLTPRPLSAEAFCPSPVTP----------------------RFQSPDPYSRPP 2454
Query: 476 TSPVSNQGFSPGSSP 490
+ P S F+P P
Sbjct: 2455 SRPQSRDPFAPLHKP 2469
Score = 38.5 bits (88), Expect = 0.020
Identities = 64/244 (26%), Positives = 87/244 (35%), Gaps = 46/244 (18%)
Query: 271 PSPLPTPLDP--EEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVS 328
P PLP PL P PALS L L +G S P SP P +
Sbjct: 932 PDPLPPPLSPIITAAAPPALSP----------LGELEYPFGAKGDSDP-ESPLAAPILET 980
Query: 329 PLSLSTEAR---RQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQP 385
P+S EA + P + P SP + + +E P P Q
Sbjct: 981 PISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQC--------SPLLQHSL 1032
Query: 386 PPPPPPASQQPPPPPPPQAPVRLPPGGPLL----------PSASLTRGPQPPPLAVTVPS 435
P P SQ PP P P L P G ++ P+ P L + S
Sbjct: 1033 VPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATS 1092
Query: 436 SLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTST 495
LP SP + P+ + APAL + +G + +P + +PGS P+ T
Sbjct: 1093 PLP-SPMGDLSCPAP----SPAPALDDF---SGLGEDTAPLDGID----APGSQPEPGQT 1140
Query: 496 LGSV 499
GS+
Sbjct: 1141 PGSL 1144
Score = 36.6 bits (83), Expect = 0.074
Identities = 61/231 (26%), Positives = 86/231 (37%), Gaps = 54/231 (23%)
Query: 316 PGSSPQHRPAGVSPLSLSTE------ARRQQASPTLSPLSPITQAVAMDALSLEQQLPYA 369
P P + P SL ++ A Q S + SPL+P + ++ +A P
Sbjct: 2387 PQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTP--RPLSAEAFCPSPVTP-R 2443
Query: 370 FFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQA----------------PVRLP--PG 411
F + +PP +PQ P P + P P PP A P LP P
Sbjct: 2444 FQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503
Query: 412 GPL---LPSA---SLTRGP-------QPPPLAVTVPSSLPQ----SPPENPG-QPSMGID 453
G L +PS + R P P P+ T P ++ + P PG P GI+
Sbjct: 2504 GELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGIN 2563
Query: 454 IASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTSTLGSVFGDAY 504
P + G P QS V+ F P SP S+ GS G++Y
Sbjct: 2564 SHFGPG-----PTLGKP--QSTNYTVATGNFHPSGSPLGPSS-GST-GESY 2605
Score = 36.6 bits (83), Expect = 0.074
Identities = 31/107 (28%), Positives = 42/107 (39%), Gaps = 22/107 (20%)
Query: 377 QQPPPQPQPPPP----------------PPPASQQPPPPPPPQAPVRLPPGGPL--LPSA 418
+Q P P+PP PP + PPP P PP PL LP+
Sbjct: 4880 KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTE 4939
Query: 419 SLTRGPQPPPLAV-TVPSSLPQSPPENPGQPSMGIDIASAPALQQYR 464
L P P PL + + P S P P P G D + P L++++
Sbjct: 4940 PLAEPPVPSPLPLASSPESARPKPRARP--PEEGED-SRPPRLKKWK 4983
Score = 35.4 bits (80), Expect = 0.17
Identities = 54/190 (28%), Positives = 68/190 (35%), Gaps = 26/190 (13%)
Query: 273 PLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSL 332
P P P+ P + + G L A L G + SPQ + + L +
Sbjct: 4173 PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQ----GVLAKNPQLRHLSPQQQQQ-LQALLM 4227
Query: 333 STEARRQQASPTLSPLS-PITQAVAMDAL-SLEQQLPYAFFTQAGSQQP---PPQPQPPP 387
+ ++ QA P P TQ + L + QL Q G Q P+PQ PP
Sbjct: 4228 QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPP 4287
Query: 388 ----PPPPASQQP------PPPPP--PQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPS 435
PP S P P PPP PQ P R P PS+ L Q PP P
Sbjct: 4288 RLPAPPGALSTGPVLGPVHPTPPPSSPQEPKR--PSQLPSPSSQLPTEAQLPPTHPGTPK 4345
Query: 436 SLPQSPPENP 445
PQ P P
Sbjct: 4346 --PQGPTLEP 4353
Score = 34.7 bits (78), Expect = 0.28
Identities = 34/118 (28%), Positives = 43/118 (36%), Gaps = 7/118 (5%)
Query: 328 SPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPP 387
+P LST A P S P + L L Q+P Q SQ P P
Sbjct: 2131 TPAGLSTSADGFLKPPAGSVPGPDSPGELF--LKLPPQVP----AQVPSQDPFGLAPAYP 2184
Query: 388 PPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENP 445
P PP PP +P P P+L ++S QP T P + P+ P P
Sbjct: 2185 LEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGT-PRHQPSTP 2241
Score = 34.7 bits (78), Expect = 0.28
Identities = 41/136 (30%), Positives = 48/136 (35%), Gaps = 37/136 (27%)
Query: 301 LTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDAL 360
L LG G QG P PA P +LST P L P+ P +
Sbjct: 4274 LQELGAGPRPQG-------PPRLPA--PPGALST-------GPVLGPVHPTPPPSSPQEP 4317
Query: 361 SLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSA-- 418
QLP + S Q P + Q PP P P PQ P PP G + P+A
Sbjct: 4318 KRPSQLP------SPSSQLPTEAQLPPTHPGT-------PKPQGPTLEPPPGRVSPAAAQ 4364
Query: 419 ------SLTRGPQPPP 428
S GP PP
Sbjct: 4365 LADTLFSKGLGPWDPP 4380
Score = 33.9 bits (76), Expect = 0.48
Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 16/83 (19%)
Query: 375 GSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGP--QPPPLAVT 432
G P P P P P SQ P P +LPP P P +GP +PPP V+
Sbjct: 4303 GPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPK---PQGPTLEPPPGRVS 4359
Query: 433 VPSSL-----------PQSPPEN 444
++ P PP+N
Sbjct: 4360 PAAAQLADTLFSKGLGPWDPPDN 4382
Score = 32.7 bits (73), Expect = 1.1
Identities = 37/131 (28%), Positives = 50/131 (38%), Gaps = 16/131 (12%)
Query: 380 PPQPQ--PPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPP-PLAVTVPSS 436
PPQP PPP A P A + G L P A GP P L + +P
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP-- 2164
Query: 437 LPQSPPENPGQPSMGIDIA---------SAPALQQYRTSAGSPANQSPTSPVSNQGFSPG 487
PQ P + P Q G+ A + P Y + G+PA Q P S++ +
Sbjct: 2165 -PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPA-QPPMLGASSRPGAGQ 2222
Query: 488 SSPQHTSTLGS 498
HT+ G+
Sbjct: 2223 PGEFHTTPPGT 2233
Score = 31.2 bits (69), Expect = 3.1
Identities = 63/269 (23%), Positives = 91/269 (33%), Gaps = 61/269 (22%)
Query: 388 PPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPE---- 443
P P ++ PPP + RL P + G P P T+ + + P
Sbjct: 3091 PGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSL 3150
Query: 444 ----NPGQPSMG---IDIASAPALQQYRT--------SAGSPANQSPTSPVSNQGFS--- 485
PGQ MG + + P T + G PA+ SP+S G S
Sbjct: 3151 GLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLL 3210
Query: 486 ------------PG------------SSPQHTSTLGSVFGDAYYEQQMAARQANALSHQL 521
PG S S L + D ++ ++ LS QL
Sbjct: 3211 EKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQL 3270
Query: 522 EQFNMMENAISSSSLYS-PGSTLNYSQAAMMGLTGSHGSLPDSQQ-----LGYASHSGIP 575
+ + SL S PG +QA + GS SL SQQ L A G+P
Sbjct: 3271 QPAQQQQQQQQQHSLLSAPGP----AQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLP 3326
Query: 576 NIILTVTGESPP--SLSKELTSSLAGVGD 602
++ PP +L + L S+A V +
Sbjct: 3327 QPLMPT---QPPAHALQQRLAPSMAMVSN 3352
Score = 30.8 bits (68), Expect = 4.1
Identities = 69/295 (23%), Positives = 97/295 (32%), Gaps = 63/295 (21%)
Query: 241 PSADQENTTALIPATHNTGGSLPDLTNIHFPSPL---PTPL---DPEEPTFPALSSSSST 294
P Q+ AL G +P HF SP PT L + PA+SS ++
Sbjct: 3987 PQQQQQQQVAL-------GPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039
Query: 295 GNLAANLTHLGIGGAGQGMST-PGS----------------SPQHRPAGVS---PLSLST 334
G L IG + M+T PG PQ +P+ + PL L
Sbjct: 4040 GPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPG 4099
Query: 335 EARRQQA--------------SPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPP 380
+ ++Q + S + S S + +A ++SL Q Q
Sbjct: 4100 QQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQ-------PGSMTQNL 4152
Query: 381 PQPQPPPPPPPASQQPPPPPPPQAPVRLP----PGGPLLPSASLTRGPQPPPLAVTVPSS 436
PQ P P P PP PV PG ++P+ R LA
Sbjct: 4153 LGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKN---- 4208
Query: 437 LPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQ 491
PQ +P Q + LQQ + +P Q P + S G PQ
Sbjct: 4209 -PQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQ 4262
Score = 30.4 bits (67), Expect = 5.3
Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 380 PPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLL--PSASLTRGPQPPPLAVTVPSSL 437
PPQ PP P + P P + P LP G L+ P +S G +P PLA+ L
Sbjct: 2930 PPQKPSAPPAPELNNSLHPTPHTKGPT-LPTGLELVNRPPSSTELG-RPNPLALEA-GKL 2986
Query: 438 PQSPPE 443
P PE
Sbjct: 2987 PCEDPE 2992
>gi|32307177 forkhead box G1 [Homo sapiens]
Length = 489
Score = 66.2 bits (160), Expect = 9e-11
Identities = 40/99 (40%), Positives = 45/99 (45%), Gaps = 14/99 (14%)
Query: 380 PPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQ 439
PP P P PPPPP QQPPPPPPP AP PP P+A +GPQ L
Sbjct: 58 PPPPAPQPPPPPQQQQPPPPPPP-AP--QPPQTRGAPAADDDKGPQQLLL---------- 104
Query: 440 SPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSP 478
PP P P+ +D A A L G P +P P
Sbjct: 105 -PPPPPPPPAAALDGAKADGLGGKGEPGGGPGELAPVGP 142
>gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1
isoform d [Homo sapiens]
Length = 756
Score = 65.5 bits (158), Expect = 1e-10
Identities = 46/132 (34%), Positives = 55/132 (41%), Gaps = 13/132 (9%)
Query: 371 FTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLA 430
+ +A QQPPPQ PPP PPP Q PPPPP +P R PPG S G
Sbjct: 588 YNRAPQQQPPPQQPPPPQPPP---QQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTST 644
Query: 431 VTVPSSLP-----QSPPENPGQPSMGIDI----ASAPALQQYRTSAG-SPANQSPTSPVS 480
TV S P PP N G S G P Y + G +PA +P P +
Sbjct: 645 PTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPT 704
Query: 481 NQGFSPGSSPQH 492
Q + S Q+
Sbjct: 705 AQTYPQPSYNQY 716
Score = 39.3 bits (90), Expect = 0.011
Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 20/100 (20%)
Query: 316 PGSSPQHRPAGVSPLSLSTEARRQQAS---PTLSPLSPITQAVAMDALSLEQQLPYAFFT 372
P SP P G S + ++ A+ PT+S SP + + Q PY
Sbjct: 615 PSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYS--------QPPYNQGG 666
Query: 373 QAGSQQPPPQPQPPPPP---------PPASQQPPPPPPPQ 403
+ PP P PPPP PA PPPPP Q
Sbjct: 667 YSQGYTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQ 706
>gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1
isoform a [Homo sapiens]
Length = 856
Score = 65.5 bits (158), Expect = 1e-10
Identities = 46/132 (34%), Positives = 55/132 (41%), Gaps = 13/132 (9%)
Query: 371 FTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLA 430
+ +A QQPPPQ PPP PPP Q PPPPP +P R PPG S G
Sbjct: 688 YNRAPQQQPPPQQPPPPQPPP---QQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTST 744
Query: 431 VTVPSSLP-----QSPPENPGQPSMGIDI----ASAPALQQYRTSAG-SPANQSPTSPVS 480
TV S P PP N G S G P Y + G +PA +P P +
Sbjct: 745 PTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPT 804
Query: 481 NQGFSPGSSPQH 492
Q + S Q+
Sbjct: 805 AQTYPQPSYNQY 816
Score = 39.3 bits (90), Expect = 0.011
Identities = 30/100 (30%), Positives = 38/100 (38%), Gaps = 20/100 (20%)
Query: 316 PGSSPQHRPAGVSPLSLSTEARRQQAS---PTLSPLSPITQAVAMDALSLEQQLPYAFFT 372
P SP P G S + ++ A+ PT+S SP + + Q PY
Sbjct: 715 PSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYS--------QPPYNQGG 766
Query: 373 QAGSQQPPPQPQPPPPP---------PPASQQPPPPPPPQ 403
+ PP P PPPP PA PPPPP Q
Sbjct: 767 YSQGYTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQ 806
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 65.1 bits (157), Expect = 2e-10
Identities = 70/261 (26%), Positives = 98/261 (37%), Gaps = 25/261 (9%)
Query: 312 GMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQA-VAMDALSLEQQLPYAF 370
G + PG P PAG +P P P + +A ++ P
Sbjct: 219 GPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVL 278
Query: 371 FTQAGSQQPPPQPQPPPPPPPA-SQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPL 429
F QPP P PP PPPP PPP PPP PP GP P GP PPL
Sbjct: 279 FPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPP---GPLGPPL 335
Query: 430 AVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSP--- 486
+ P LP PP P P+ ++ PA T++G P + S P ++ P
Sbjct: 336 TLAPPPHLPGPPPGAP-PPAPHVN----PAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPY 390
Query: 487 -----GSSPQHTSTLGSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGS 541
G + T + +A +E+ M +A + S + A+S +S GS
Sbjct: 391 DRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSS-------AISRAVSDASAGDYGS 443
Query: 542 TLNYSQAAMMGLTGSHGSLPD 562
+ A+ + S S D
Sbjct: 444 AIETLVTAISLIKQSKVSADD 464
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/113 (32%), Positives = 45/113 (39%), Gaps = 17/113 (15%)
Query: 375 GSQQPPPQPQPPPPPPPASQQPPP-----PPPPQAPVRLPPGGPLLP---SASLTRGPQP 426
G + P P PPPP + Q PP PP P P PP G +LP + RG +P
Sbjct: 214 GDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP 273
Query: 427 PPLAVTVPSSLPQSPPENPGQPSMG-IDIASAPALQQYRTSAGSPANQSPTSP 478
PP P P P GQP +G + P + Y G P Q P
Sbjct: 274 PP-----PVLFPGQP---FGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPP 318
Score = 34.7 bits (78), Expect = 0.28
Identities = 22/63 (34%), Positives = 25/63 (39%), Gaps = 3/63 (4%)
Query: 389 PPPASQQPPPPPPPQAPVRLP---PGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENP 445
PP S + P + R P PGG P + GP PP A P P PP P
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPP 247
Query: 446 GQP 448
G P
Sbjct: 248 GPP 250
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 65.1 bits (157), Expect = 2e-10
Identities = 34/66 (51%), Positives = 38/66 (57%), Gaps = 8/66 (12%)
Query: 377 QQPPPQPQ-PPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPS 435
QQPPP PQ PPPPPPP QQ PPPPPP PP P + ++ P PP +A VP
Sbjct: 755 QQPPPPPQQPPPPPPPQQQQQPPPPPP------PPSMPQQAAPAMKSSP-PPFIATQVPV 807
Query: 436 SLPQSP 441
PQ P
Sbjct: 808 LEPQLP 813
Score = 55.8 bits (133), Expect = 1e-07
Identities = 62/227 (27%), Positives = 80/227 (35%), Gaps = 44/227 (19%)
Query: 268 IHFPSP-LPT--PLDPEEPTFPALSSSSSTGNLAAN--LTHLGIGGAGQGMSTPGSSPQH 322
+H P P LP P PE T P L+ + A + L + + + P
Sbjct: 828 LHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA-- 885
Query: 323 RPAGVSPLSLST------------EARRQQASPTLSPLSPITQAVAMDALS-LEQQLPYA 369
RP VSP T + + P PL+ + + + L ++ P
Sbjct: 886 RPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLL 945
Query: 370 FFTQAGSQQPPPQPQPP------------PPPPPASQQPPPP---PPPQAPVRLPPGGPL 414
+ SQ PPP P PP PPPPP QPPP PP PV L
Sbjct: 946 PSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQ----- 1000
Query: 415 LPSASLTRGPQPPPLAVTVPSSLP---QSPPENPGQPSMGIDIASAP 458
P T QPPP P P Q PP P +P I +P
Sbjct: 1001 -PMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSP 1046
Score = 50.4 bits (119), Expect = 5e-06
Identities = 33/96 (34%), Positives = 39/96 (40%), Gaps = 30/96 (31%)
Query: 363 EQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTR 422
EQ+ + Q Q P P PQ PPPPP QQPPPPPPPQ + PP
Sbjct: 734 EQKKHHHHHHQQMQQAPAPVPQQPPPPP---QQPPPPPPPQQQQQPPP------------ 778
Query: 423 GPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAP 458
PPP PP P Q + + + P
Sbjct: 779 ---PPP------------PPSMPQQAAPAMKSSPPP 799
Score = 48.9 bits (115), Expect = 1e-05
Identities = 40/143 (27%), Positives = 54/143 (37%), Gaps = 9/143 (6%)
Query: 308 GAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLP 367
G G+G G++ GVS + +T+A + T P P QA ++ L
Sbjct: 178 GRGRGRKETGTAKP----GVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDL- 232
Query: 368 YAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPP 427
PPQP PPP P QPPP P PQ PP P T+
Sbjct: 233 --IVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKR 290
Query: 428 PLAVTVPSSLP--QSPPENPGQP 448
T P+++ PP P +P
Sbjct: 291 KADTTTPTTIDPIHEPPSLPPEP 313
Score = 47.0 bits (110), Expect = 6e-05
Identities = 59/204 (28%), Positives = 71/204 (34%), Gaps = 32/204 (15%)
Query: 316 PGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAG 375
P Q P P S+ QQA+P + P +A LE QLP + F G
Sbjct: 769 PPQQQQQPPPPPPPPSMP-----QQAAPAMKSSPP--PFIATQVPVLEPQLPGSVFDPIG 821
Query: 376 SQQPPPQPQPPPPPPPASQQPP----PP--------PPPQAPVRLP--PGGPLLPSASLT 421
P P P PP QPP PP PP LP P P +A+L
Sbjct: 822 HFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALP 881
Query: 422 RGPQPPPL---AVTVPSSLPQSPPENPGQPSMGIDIASAPALQ--------QYRTSAGSP 470
P PP A+T LPQ P P Q + + AP L Q P
Sbjct: 882 PKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941
Query: 471 ANQSPTSPVSNQGFSPGSSPQHTS 494
P+ V +Q P P H S
Sbjct: 942 TPLLPSVKVQSQPPPPLPPPPHPS 965
Score = 47.0 bits (110), Expect = 6e-05
Identities = 45/131 (34%), Positives = 53/131 (40%), Gaps = 19/131 (14%)
Query: 377 QQPPPQPQPPPPP----PPASQQPPPPPPPQAPVRLP--PGGPLLPSASLTRG----PQP 426
QQPPP P PP P P PPP Q PV P PG P T+ PQP
Sbjct: 774 QQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQP 833
Query: 427 PPLAVTVPSSLPQSPPENPGQPSMGID-IASAPALQQYRTSAGS-PANQSPTSPVSNQGF 484
+P LPQ PPE+ P + + S PAL S P+N++ P
Sbjct: 834 -----ELPPHLPQ-PPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALP-PKPAR 886
Query: 485 SPGSSPQHTST 495
P SP T T
Sbjct: 887 PPAVSPALTQT 897
Score = 43.1 bits (100), Expect = 8e-04
Identities = 32/109 (29%), Positives = 39/109 (35%), Gaps = 9/109 (8%)
Query: 372 TQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAV 431
TQA + PQP PPP A+ P P P V+ P + P T P PP
Sbjct: 200 TQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ--- 256
Query: 432 TVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVS 480
PQ PP QP A Q +T G T+P +
Sbjct: 257 ------PQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 65.1 bits (157), Expect = 2e-10
Identities = 34/72 (47%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 379 PPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLP 438
P PQPQPPPPPPP P PPP AP P P LP P PPP P++ P
Sbjct: 1465 PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPP--PPPPAAAP 1522
Query: 439 -QSPPENPGQPS 449
+PPE P PS
Sbjct: 1523 LAAPPEEPAAPS 1534
Score = 64.3 bits (155), Expect = 3e-10
Identities = 50/145 (34%), Positives = 62/145 (42%), Gaps = 24/145 (16%)
Query: 338 RQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPP-QPQPPPPPPPA---S 393
+ ++P PL+P A A+ LP A G+ +PP + +PPP PPPA
Sbjct: 1414 KDTSTPDGPPLAP---AAAVPGPPPLPGLPSA--NSNGTPEPPLLEEKPPPTPPPAPTPQ 1468
Query: 394 QQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGID 453
QPPPPPPP P LP PL+ A P PPPL P ++P PP P
Sbjct: 1469 PQPPPPPPPPQPA-LPSPPPLV--APTPSSPPPPPLPPPPPPAMPSPPPPPP-------- 1517
Query: 454 IASAPALQQYRTSAGSPANQSPTSP 478
PA PA SP P
Sbjct: 1518 ----PAAAPLAAPPEEPAAPSPEDP 1538
Score = 62.4 bits (150), Expect = 1e-09
Identities = 57/194 (29%), Positives = 72/194 (37%), Gaps = 41/194 (21%)
Query: 245 QENTTALIPATHNTGGSLPDLTNIHFPSPL-PTPLDPEEPTFPALSSSSSTGNLAANLTH 303
QE+ ++ I A + + P T+ PL P P P P L S++S G L
Sbjct: 1395 QESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPL-- 1452
Query: 304 LGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLE 363
+ P +PQ +P P Q A P+ PL T +
Sbjct: 1453 --LEEKPPPTPPPAPTPQPQPPPPPPPP-------QPALPSPPPLVAPTPS--------- 1494
Query: 364 QQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRG 423
PPP P PPPPPP PPPPPP AP+ PP P PS
Sbjct: 1495 --------------SPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPS------ 1534
Query: 424 PQPPPLAVTVPSSL 437
P+ P L T P L
Sbjct: 1535 PEDPELPDTRPLHL 1548
Score = 44.3 bits (103), Expect = 4e-04
Identities = 61/235 (25%), Positives = 83/235 (35%), Gaps = 46/235 (19%)
Query: 271 PSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGA-------GQGMSTPGSSPQHR 323
PS L P+ P PA+ +G G+GGA G G+ P SP R
Sbjct: 1315 PSVPARGLQPQPPATPAVPHPPPSGAF-------GLGGALEAAESEGLGLGCP--SPCKR 1365
Query: 324 PAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQP 383
L E +R + P + D+++ + L + + + PP
Sbjct: 1366 --------LDEELKRNLET------LPSFSSDEEDSVAKNRDLQESISSAISALDDPPLA 1411
Query: 384 QPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQ-------PPPLAVTVPSS 436
P P PP P A V PP P LPSA+ P+ PPP P+
Sbjct: 1412 GPKDTSTPDG----PPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467
Query: 437 LPQ-SPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSP 490
PQ PP P QP+ + S P L S+ P P P + P P
Sbjct: 1468 QPQPPPPPPPPQPA----LPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP 1518
Score = 43.9 bits (102), Expect = 5e-04
Identities = 69/285 (24%), Positives = 90/285 (31%), Gaps = 85/285 (29%)
Query: 297 LAANLTHLGIG----GAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSP-I 351
LA ++ H G G GA S P P + +P L EA L P P +
Sbjct: 742 LATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQL 801
Query: 352 TQAVAMDALSLEQQLPYAFF------TQAGSQQPPPQPQPPPPP---------------- 389
+V A S T+ G+ QPPP P PPPPP
Sbjct: 802 LPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEP 861
Query: 390 --------------PPASQQP--------PPPP------PPQAPVRLPPGGPLLPSASLT 421
PP + Q PP P PP + + P G PS T
Sbjct: 862 AAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGT 921
Query: 422 RGPQPPPL-AVTVPSSLPQ-------------------------SPPENPGQPSMGI-DI 454
+ P+ PL ++ P SL Q PPE+ G P G
Sbjct: 922 KAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPP 981
Query: 455 ASAPALQQYRT-SAGSPANQSPTSPVSNQGFSPGSSPQHTSTLGS 498
PA Y G + P +P G P P+ ST+ +
Sbjct: 982 PGPPAYDPYGPYCPGRASGAGPETP--GLGLDPNKPPELPSTVNA 1024
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/144 (30%), Positives = 52/144 (36%), Gaps = 28/144 (19%)
Query: 265 LTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAG----QGMSTPGSSP 320
LT+I FP L D E FP + G AA+ G AG +G G+ P
Sbjct: 929 LTSICFPDSLLQ--DEERSFFPTMEEMFGGG--AAD----DYGKAGPPEDEGDPKAGAGP 980
Query: 321 QHRPAGVSPLSLSTEARRQQASPT-----LSPLSP--ITQAVAMDALSLEQQLPYAFFTQ 373
P P R A P L P P + V + L L Q
Sbjct: 981 PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGL---------IQ 1031
Query: 374 AGSQQPPPQPQPPPPPPPASQQPP 397
+G Q P P PPPPPPPA P
Sbjct: 1032 SGPHQAAPPPPPPPPPPPAPASEP 1055
Score = 40.8 bits (94), Expect = 0.004
Identities = 79/291 (27%), Positives = 98/291 (33%), Gaps = 55/291 (18%)
Query: 256 HNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPAL-----SSSSSTGNLAANLTHLGIGGAG 310
H+ G + PD + ++ S L + P+ +L S S T T L I GA
Sbjct: 77 HHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGAL 136
Query: 311 QGMST-PGSSP----QH------RPAGV-SPLSLSTEARRQQASPTLSP-----LSPITQ 353
G ST P SS QH RP V S LSL A+ LSP L P
Sbjct: 137 PGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQA 196
Query: 354 AVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGP 413
+L E+ AG P P PP +P PP PP P LP
Sbjct: 197 PTVPSSLGFERL--------AGGGVLGPAGLGPAQTPP--YRPGPPDPPPPPRHLPTQFN 246
Query: 414 LL--PSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDI---------------AS 456
LL SA+ Q P + P PP P I
Sbjct: 247 LLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPP 306
Query: 457 APALQQYRTSAGSPANQS-----PTSPVSNQGFSPGS-SPQHTSTLGSVFG 501
A ALQ Y + GS + SP+ SPG+ P G+ G
Sbjct: 307 AHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAG 357
Score = 40.8 bits (94), Expect = 0.004
Identities = 58/227 (25%), Positives = 76/227 (33%), Gaps = 43/227 (18%)
Query: 241 PSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPE------EPTFPA------- 287
PSA + L PAT + G P P P+P L+ EP P+
Sbjct: 814 PSASKVGVHLLEPATRD-GAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEE 872
Query: 288 -LSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGV--SPLSLSTEARRQQASPT 344
L + L L L G+ P S + PAG SP T+A R
Sbjct: 873 SLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKD-PAGAYRSPSPQGTKAPR------ 925
Query: 345 LSPLSPITQAVAMDALSLEQQLPY------AFFTQAGSQQPPPQPQPPPPPPPASQQPPP 398
P+T D+L +++ + F A P P A PPP
Sbjct: 926 ---FVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPP 982
Query: 399 PPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENP 445
PP P GP P + GP+ P L + P PPE P
Sbjct: 983 GPPAYDPY-----GPYCPGRASGAGPETPGLGLD-----PNKPPELP 1019
Score = 37.0 bits (84), Expect = 0.057
Identities = 32/92 (34%), Positives = 39/92 (42%), Gaps = 19/92 (20%)
Query: 375 GSQQPPPQ-PQPPPPP---------PPASQQP----PPPPPPQAPVRLPPGGPLLPSASL 420
GS PPP+ P PPP P P Q P P PP P+ P L P +
Sbjct: 1688 GSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKV 1747
Query: 421 TRGPQPPPLAVTVPSSLPQSPPEN---PGQPS 449
TRG + PL +S Q+ PE GQP+
Sbjct: 1748 TRGER--PLRGERATSGRQTRPERSLATGQPA 1777
Score = 35.0 bits (79), Expect = 0.22
Identities = 30/113 (26%), Positives = 42/113 (37%), Gaps = 6/113 (5%)
Query: 304 LGIGGAGQGMSTPG----SSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDA 359
L + AG+G+ T S H S EA+ ++ + A +D
Sbjct: 1229 LSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDF 1288
Query: 360 LSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGG 412
L ++ P + QAG P P+ PP PA P PP A PP G
Sbjct: 1289 LKSGKRHPPLY--QAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSG 1339
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 63.9 bits (154), Expect = 4e-10
Identities = 58/175 (33%), Positives = 70/175 (40%), Gaps = 36/175 (20%)
Query: 286 PALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHR----PAGVSPLSLSTEARRQQA 341
P + SS L+ H I A Q M S+ Q PA + P
Sbjct: 607 PKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPP-----------P 655
Query: 342 SPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPP 401
P S L ++ A M +S AG PPP P PPP PPP+S PPPPPP
Sbjct: 656 PPLPSGLGSLSPAPPMPPVS------------AGPPLPPPPPPPPPLPPPSSAGPPPPPP 703
Query: 402 ----PQAPVRLPPGGPLLPSASLTRG---PQPPPLAVTVPSSLPQSPPENPGQPS 449
P +P PGGP P A G P PP L + SS Q P + +PS
Sbjct: 704 PPPLPNSPAPPNPGGP--PPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPS 756
Score = 58.9 bits (141), Expect = 1e-08
Identities = 45/112 (40%), Positives = 49/112 (43%), Gaps = 27/112 (24%)
Query: 379 PPPQPQ------PPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVT 432
PPP P P PP PP S PP PPPP PP PL P +S GP PPP
Sbjct: 655 PPPLPSGLGSLSPAPPMPPVSAGPPLPPPP------PPPPPLPPPSS--AGPPPPP---- 702
Query: 433 VPSSLPQSP-PENPG-----QPSMGIDIASAPALQQYRTSAGSPANQSPTSP 478
P LP SP P NPG P G+ P L GS ++Q P P
Sbjct: 703 PPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGL---FFGLGSSSSQCPRKP 751
Score = 37.0 bits (84), Expect = 0.057
Identities = 37/121 (30%), Positives = 43/121 (35%), Gaps = 11/121 (9%)
Query: 364 QQLPYAFFTQAGSQQPPPQPQPP------PPPPPASQQPPPPPPPQAPVRLPPGGPLLPS 417
Q +P + SQ PP P AS Q PPP P +PP P LPS
Sbjct: 604 QLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPP--PASIPPPPP-LPS 660
Query: 418 ASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTS 477
+ P PP V+ LP PP P P A P SPA +P
Sbjct: 661 GLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPP--SSAGPPPPPPPPPLPNSPAPPNPGG 718
Query: 478 P 478
P
Sbjct: 719 P 719
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 63.5 bits (153), Expect = 6e-10
Identities = 54/210 (25%), Positives = 80/210 (38%), Gaps = 15/210 (7%)
Query: 253 PATHNTGGSLPDLTNIHFPSPLPTPLDPEE------PTFPALSSSSSTGNLAANLTHLGI 306
P++ + L D++ P+PLP + EE P P L + + +
Sbjct: 560 PSSRPSSTGLEDIS----PTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVAL 615
Query: 307 GGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQL 366
G T + + + + +S + ++P S P V A ++
Sbjct: 616 DLVGDRTPTSEKMDEGQQSSGEDMEISDD--EMPSAPITSADCPKPMVVTPGAAAVAA-- 671
Query: 367 PYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQP 426
P PP P PPPPPP QP P PP P PP P P+ ++ P P
Sbjct: 672 PSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLP 731
Query: 427 PPLAVTVPSSLPQSPPENPGQ-PSMGIDIA 455
P V P LP PP PG P M +D++
Sbjct: 732 APPGVPPPPILPPLPPFPPGLFPVMQVDMS 761
Score = 52.8 bits (125), Expect = 1e-06
Identities = 69/235 (29%), Positives = 91/235 (38%), Gaps = 41/235 (17%)
Query: 242 SADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEP-TFPALSSSSSTGNLAAN 300
S + +T +PAT G P L+ L +P P P ++PA S S S+G L
Sbjct: 1326 SLAKSQSTETVPATP---GGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRT 1382
Query: 301 LTHLGIGGAGQGMS-TPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDA 359
G+ S TP S P + L T R +++ P SP+ + +
Sbjct: 1383 --------PGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPV--LLETGLPLP 1432
Query: 360 LSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPP-PPPPQAPVRLPPG-----GP 413
L L LP A +Q P P PP P P + PPP P P R PP GP
Sbjct: 1433 LPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGP 1492
Query: 414 LL-PSASLTRG---------PQPP-------PLAVTVP---SSLPQSPPENPGQP 448
L+ P A G PQ P P VT+ + +P PP P QP
Sbjct: 1493 LVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQP 1547
Score = 47.4 bits (111), Expect = 4e-05
Identities = 50/202 (24%), Positives = 74/202 (36%), Gaps = 31/202 (15%)
Query: 313 MSTPGSSPQHRPAGVS--PLSLSTE------------ARRQQASPTLSPLSPITQAVAMD 358
+ T +P+ RP+ + PL + E Q+ + LSP P + A
Sbjct: 1193 IETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP 1252
Query: 359 ALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSA 418
LS E+ + + P P PP PPP + P PP PP P P +P
Sbjct: 1253 PLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPP--RPPRPPSPPPEPETTDASHPSVPPE 1310
Query: 419 SLTRG--PQPPPL---------AVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSA 467
L P P L TVP++ PP + G + + P + A
Sbjct: 1311 PLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPG-SPFSYPA 1369
Query: 468 GSPANQS---PTSPVSNQGFSP 486
SP+ S P +P + F+P
Sbjct: 1370 PSPSLSSGGLPRTPGRDFSFTP 1391
Score = 47.0 bits (110), Expect = 6e-05
Identities = 52/195 (26%), Positives = 69/195 (35%), Gaps = 56/195 (28%)
Query: 354 AVAMDALSLEQQ---------------------LPYAFFTQAGSQQPPPQP--------- 383
A A+D+L +E++ LP A S++PP +P
Sbjct: 1179 APAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAML 1238
Query: 384 -QPPPPPPPASQQPPPPP----------PPQAPVRLP-PGGPLLPSASLTRGPQPPPLAV 431
P PP +PP P P+ P+ LP P P LP R P PPP
Sbjct: 1239 LSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPE 1298
Query: 432 TVPSSLPQSPPE------NPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFS 485
T +S P PPE P P + +A + Q T +P + P S G S
Sbjct: 1299 TTDASHPSVPPEPLAEDHPPHTPGLCGSLAKS---QSTETVPATPGGEPPLS-----GGS 1350
Query: 486 PGSSPQHTSTLGSVF 500
G S GS F
Sbjct: 1351 SGLSLSSPQVPGSPF 1365
Score = 44.3 bits (103), Expect = 4e-04
Identities = 43/147 (29%), Positives = 53/147 (36%), Gaps = 14/147 (9%)
Query: 266 TNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPA 325
T + P PLP PL P L + + L + M P+ P
Sbjct: 1427 TGLPLPLPLPLPLPLALPA--VLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPP 1484
Query: 326 GVSPLSLSTEARRQQASPTLSP---LSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQ 382
S LSL R A L L P + + + + F AG PPP
Sbjct: 1485 --SMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPP- 1541
Query: 383 PQPPPPPPPASQQPPPPPPPQAPVRLP 409
P PP PPPP PPPPP P +LP
Sbjct: 1542 PLPPQPPPP------PPPPPVEPTKLP 1562
Score = 39.7 bits (91), Expect = 0.009
Identities = 52/195 (26%), Positives = 75/195 (38%), Gaps = 28/195 (14%)
Query: 283 PTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQ--- 339
P A++ +++ +++L +GG G G S P P P +T A
Sbjct: 334 PAVTAVAGATAAFRGSSDLPFGAVGGTG-GSSGP-------PFKAQPQDSATFAHTPPPA 385
Query: 340 QASPT---LSPLSPITQAVAMDALSLEQQLPYAFF--TQAGSQQPPPQPQPPPPPPPASQ 394
QA+P S SP VA E+ A F +G + P P P PP P ++
Sbjct: 386 QATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAK 445
Query: 395 Q----PPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSM 450
+ PP PPPP G P T G P P +L +S P P +P
Sbjct: 446 EKPGTPPGPPPPDTNSMELGGRP-------TFGWSPEPCDSPGTPTL-ESSPAGPEKPHD 497
Query: 451 GIDIASAPALQQYRT 465
+D L++ RT
Sbjct: 498 SLDSRIEMLLKEQRT 512
Score = 33.5 bits (75), Expect = 0.63
Identities = 62/260 (23%), Positives = 83/260 (31%), Gaps = 35/260 (13%)
Query: 349 SPITQAVA--MDALSLEQQLPYAFFTQAGSQQPPP---QPQPPPP----PPPASQQPPPP 399
SP AVA A LP+ G PP QPQ PPPA P P
Sbjct: 333 SPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPG 392
Query: 400 -----PPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDI 454
P Q PV P P P+A+ G + P+ P P E + G
Sbjct: 393 FKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPP 452
Query: 455 ASAPALQQYRTSAGSPA-NQSPTSPVSNQGFSPGSSPQHTSTLGSVFGDAYYEQQMAARQ 513
P G P SP P SP + S G + +R
Sbjct: 453 GPPPPDTNSMELGGRPTFGWSP---------EPCDSPGTPTLESSPAGPEKPHDSLDSRI 503
Query: 514 ANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLT--------GSHGSLPDSQQ 565
L Q + + S + L GS ++ S + + L G G P S +
Sbjct: 504 EMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSR 563
Query: 566 LGYASHSGIPNIILTVTGES 585
S +G+ +I T +S
Sbjct: 564 ---PSSTGLEDISPTPLPDS 580
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 62.8 bits (151), Expect = 1e-09
Identities = 101/385 (26%), Positives = 133/385 (34%), Gaps = 85/385 (22%)
Query: 128 GSPHRRPLSVD-KHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQPESFSS 186
G P R P + G Q C ++ +SP RR + HQ T + +QP S
Sbjct: 762 GLPGRPPCPPGAESGPQTKFCSEISLIVSP------RRISVQLDSHQPTQSISQPPPPPS 815
Query: 187 GSQDVHQKRVLLLTVPGMEETTSEADKNLSKQ---AWDTKKTGSRPKSCEVPGINIFPSA 243
LL G + S+ ++S + + + + + SC +P P
Sbjct: 816 -----------LLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCT 864
Query: 244 DQENTTALIPATHNTGGSLPDLTNIHFPS---PLPTPLDPEE---PTFPALSSSSSTGNL 297
+ ++ + LP +T PS P P PL E P P L
Sbjct: 865 ESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP-------- 916
Query: 298 AANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAM 357
G G+ P P AG+ PL A P P +
Sbjct: 917 ------------GAGIPPPPPLPG---AGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG 961
Query: 358 DALSLEQQLPYAFFTQAGSQQPPPQPQ---PPPPPPPASQQPPPPPPPQAPVRLPPGGPL 414
+ L LP AG PPP P PPPPP P + PPPPP P A + P P
Sbjct: 962 AGIPLPPPLP-----GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---PPPPP 1013
Query: 415 LPSASLTRGPQPPPL---AVTVPSSLPQS----PPENPG------QPSMGIDIASAPALQ 461
LP A + P PPPL + P LP + PP PG P G I P L
Sbjct: 1014 LPGAGI---PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL- 1069
Query: 462 QYRTSAGSPANQSPTSPVSNQGFSP 486
AG P P P+ G P
Sbjct: 1070 ---PGAGIP----PPPPLPGAGIPP 1087
Score = 62.0 bits (149), Expect = 2e-09
Identities = 53/141 (37%), Positives = 58/141 (41%), Gaps = 29/141 (20%)
Query: 374 AGSQQPPPQPQ---PPPPPPPASQQPPPPPPPQA----PVRLPPGG----PLLPSASLTR 422
AG PPP P PPPPP P + PPPPP P+ P LP G P LP A +
Sbjct: 1116 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP 1175
Query: 423 GPQPPPLAVTVPSSLP----QSPPENPGQ--------PSMGIDIASAPALQQYRTSAGSP 470
P P + + P LP PP PG P MGI A AP L T P
Sbjct: 1176 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP 1235
Query: 471 ANQSPTSPVSNQGFSP--GSS 489
P PVS P GSS
Sbjct: 1236 ----PLLPVSGPPLLPQVGSS 1252
Score = 57.8 bits (138), Expect = 3e-08
Identities = 46/122 (37%), Positives = 52/122 (42%), Gaps = 27/122 (22%)
Query: 374 AGSQQPPPQPQ---PPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLA 430
AG PPP P PPPPP P + PPPPP P A + P P LP A + P PPPL
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---PPPPPLPGAGI---PPPPPL- 1080
Query: 431 VTVPSSLPQSPPENPG------QPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGF 484
P + PP PG P G+ I P L AG P P P+ G
Sbjct: 1081 ---PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL----PGAGIP----PPPPLPGAGI 1129
Query: 485 SP 486
P
Sbjct: 1130 PP 1131
Score = 57.4 bits (137), Expect = 4e-08
Identities = 44/129 (34%), Positives = 52/129 (40%), Gaps = 19/129 (14%)
Query: 374 AGSQQPPPQPQ---PPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLA 430
AG PPP P PPPPP P + PPPPP P A + P P LP A + P P +
Sbjct: 1050 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---PPPPPLPGAGIPPPPPLPGVG 1106
Query: 431 VTVPSSLPQS----PPENPG------QPSMGIDIASAPALQQYRTSAGSP---ANQSPTS 477
+ P LP + PP PG P G I P L + P A P
Sbjct: 1107 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPP 1166
Query: 478 PVSNQGFSP 486
P+ G P
Sbjct: 1167 PLPGAGIPP 1175
Score = 55.8 bits (133), Expect = 1e-07
Identities = 42/105 (40%), Positives = 47/105 (44%), Gaps = 11/105 (10%)
Query: 374 AGSQQPPPQPQ---PPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPL- 429
AG PPP P PPPPP P PPPPP P V +PP P LP A + P PPPL
Sbjct: 1160 AGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLP--GVGIPPPPP-LPGAGI---PPPPPLP 1213
Query: 430 -AVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQ 473
P+ P PP G P + S P L S+ P Q
Sbjct: 1214 GMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQ 1258
Score = 40.8 bits (94), Expect = 0.004
Identities = 23/51 (45%), Positives = 25/51 (49%), Gaps = 2/51 (3%)
Query: 380 PPQPQPPPPPPPASQQPPPPPPPQAPVRLPP-GGPLLPSASLTRGPQPPPL 429
PP P PP PPP PPP P P LP G LP+ + G PPPL
Sbjct: 1218 PPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVC-GFLPPPL 1267
Score = 37.0 bits (84), Expect = 0.057
Identities = 41/149 (27%), Positives = 60/149 (40%), Gaps = 12/149 (8%)
Query: 348 LSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVR 407
LS I QA+ + +QQL Q QQ +P PP S QP +
Sbjct: 196 LSDIQQAIRLQQQQ-QQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLL 254
Query: 408 LPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQS---PPENPGQPSM--GIDIASAPALQQ 462
P GG A G A++ S LP+S P P QP G+ ++ AP+L
Sbjct: 255 GPSGG-----AGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPA 309
Query: 463 YRTSA-GSPANQSPTSPVSNQGFSPGSSP 490
+ +A SP++ + P + G +P
Sbjct: 310 AQPAAKDSPSSTAFPFPEAGPGEEAAGAP 338
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 62.8 bits (151), Expect = 1e-09
Identities = 51/157 (32%), Positives = 66/157 (42%), Gaps = 16/157 (10%)
Query: 309 AGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPY 368
A S GSSPQ+ + S E ++ A+ + P+ A + L + Q P
Sbjct: 362 ANLDQSQRGSSPQN----TTTPKPSVEGQQPAAA---AACEPVDHAQSESILKVSQ--PR 412
Query: 369 AFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAP----VRLPPGGPLLPSASL-TRG 423
A QA + PPP P PP P +++ PPPPPPP P LP P P L
Sbjct: 413 ALEQQAST--PPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMA 470
Query: 424 PQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPAL 460
P PPL +P S PP P P +G P L
Sbjct: 471 PPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLL 507
Score = 49.7 bits (117), Expect = 8e-06
Identities = 39/115 (33%), Positives = 45/115 (39%), Gaps = 25/115 (21%)
Query: 316 PGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAG 375
PGSS + P P S A+ A PT P P+ AM
Sbjct: 431 PGSSAEPPPPPPPPPLPSVGAK---ALPTAPPPPPLPGLGAM------------------ 469
Query: 376 SQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRL-PPGGPLLPSASLTRGPQPPPL 429
PP P PPP P + + PPPPPP + PP PLLP P PPPL
Sbjct: 470 ---APPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPL 521
Score = 29.6 bits (65), Expect = 9.1
Identities = 23/101 (22%), Positives = 36/101 (35%), Gaps = 3/101 (2%)
Query: 379 PPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLP 438
P P + P A+ +P ++ +++ L AS P PPP +P S
Sbjct: 379 PKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQAST---PPPPPPPPLLPGSSA 435
Query: 439 QSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPV 479
+ PP P P + + P G A P P+
Sbjct: 436 EPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPL 476
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 62.8 bits (151), Expect = 1e-09
Identities = 51/157 (32%), Positives = 66/157 (42%), Gaps = 16/157 (10%)
Query: 309 AGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPY 368
A S GSSPQ+ + S E ++ A+ + P+ A + L + Q P
Sbjct: 362 ANLDQSQRGSSPQN----TTTPKPSVEGQQPAAA---AACEPVDHAQSESILKVSQ--PR 412
Query: 369 AFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAP----VRLPPGGPLLPSASL-TRG 423
A QA + PPP P PP P +++ PPPPPPP P LP P P L
Sbjct: 413 ALEQQAST--PPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMA 470
Query: 424 PQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPAL 460
P PPL +P S PP P P +G P L
Sbjct: 471 PPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLL 507
Score = 49.7 bits (117), Expect = 8e-06
Identities = 39/115 (33%), Positives = 45/115 (39%), Gaps = 25/115 (21%)
Query: 316 PGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAG 375
PGSS + P P S A+ A PT P P+ AM
Sbjct: 431 PGSSAEPPPPPPPPPLPSVGAK---ALPTAPPPPPLPGLGAM------------------ 469
Query: 376 SQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRL-PPGGPLLPSASLTRGPQPPPL 429
PP P PPP P + + PPPPPP + PP PLLP P PPPL
Sbjct: 470 ---APPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPL 521
Score = 29.6 bits (65), Expect = 9.1
Identities = 23/101 (22%), Positives = 36/101 (35%), Gaps = 3/101 (2%)
Query: 379 PPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLP 438
P P + P A+ +P ++ +++ L AS P PPP +P S
Sbjct: 379 PKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQAST---PPPPPPPPLLPGSSA 435
Query: 439 QSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPV 479
+ PP P P + + P G A P P+
Sbjct: 436 EPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPL 476
>gi|190343021 Sec24-related protein D [Homo sapiens]
Length = 1032
Score = 62.8 bits (151), Expect = 1e-09
Identities = 66/245 (26%), Positives = 86/245 (35%), Gaps = 52/245 (21%)
Query: 270 FPSPLPT--------PLDPE-EPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSP 320
FP P P P P + ++P S+SS L + L+ + I G GM+ P P
Sbjct: 84 FPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGP 143
Query: 321 QHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPP 380
P +S SL T R P S L P +Q + +L S P
Sbjct: 144 ---PGPLSATSLQTPPR----PPQPSILQPGSQVLPPPPTTLNGP--------GASPLPL 188
Query: 381 PQPQPP----PPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSS 436
P +P PPPP A QPPP P PP GPQ ++ P
Sbjct: 189 PMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPP-------QQANSGPQMAGAQLSYPGG 241
Query: 437 LPQSPPE--NPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTS 494
P P + P QP +D S P SP + N S G T+
Sbjct: 242 FPGGPAQMAGPPQPQKKLDPDSIP---------------SPIQVIENDRASRGGQVYATN 286
Query: 495 TLGSV 499
T G +
Sbjct: 287 TRGQI 291
Score = 55.8 bits (133), Expect = 1e-07
Identities = 71/244 (29%), Positives = 90/244 (36%), Gaps = 26/244 (10%)
Query: 259 GGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQ-GMSTPG 317
G S P + PS +P +P P L ++++ G L G GQ G G
Sbjct: 20 GLSPPHYGHYGDPSHTASPTGMMKPAGP-LGATATRGMLPPGPPPPGPHQFGQNGAHATG 78
Query: 318 SSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQ 377
PQ P ++++ Q S S PI+ + L QL GS
Sbjct: 79 HPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTS---SVTQLGSQLSAMQINSYGSG 135
Query: 378 QPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLT---RGPQPPPLAVTVP 434
PP Q PP P A+ PP PPQ P L PG +LP T G P PL + P
Sbjct: 136 MAPPS-QGPPGPLSATSLQTPPRPPQ-PSILQPGSQVLPPPPTTLNGPGASPLPLPMYRP 193
Query: 435 SSLPQSPPENPG-QPSMGIDIASAPALQQYRTSAGSPANQSPTSP------VSNQGFSPG 487
L PP N QP P L AG P Q+ + P +S G PG
Sbjct: 194 DGLSGPPPPNAQYQP---------PPLPGQTLGAGYPPQQANSGPQMAGAQLSYPGGFPG 244
Query: 488 SSPQ 491
Q
Sbjct: 245 GPAQ 248
Score = 33.1 bits (74), Expect = 0.82
Identities = 35/128 (27%), Positives = 41/128 (32%), Gaps = 19/128 (14%)
Query: 372 TQAGSQQPPPQPQPPP----PPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPP 427
+Q G PP QP P PP P + P GPL A+ TRG PP
Sbjct: 2 SQQGYVATPPYSQPQPGIGLSPPHYGHYGDPSHTASPTGMMKPAGPL--GATATRGMLPP 59
Query: 428 PLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPG 487
P PG G + A A R P N +S Q +
Sbjct: 60 G-------------PPPPGPHQFGQNGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQS 106
Query: 488 SSPQHTST 495
S P ST
Sbjct: 107 SYPGPIST 114
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.4 bits (150), Expect = 1e-09
Identities = 77/286 (26%), Positives = 104/286 (36%), Gaps = 33/286 (11%)
Query: 235 PGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPT--FPALSSSS 292
PG+ A + +++GGS P L S P P FP S
Sbjct: 98 PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH 157
Query: 293 STGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEAR---------RQQASP 343
+G + G S P S P P+ P+ S R RQ +
Sbjct: 158 RSGPPEPQRNRMPPPRPDVG-SKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG 216
Query: 344 TLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQP-PPQP------QPPPPPPPASQQP 396
P P + A+ S+ Q P + + ++ P PP P +PPPPPPP +P
Sbjct: 217 PTPPPFPGNRGTALGGGSIRQS-PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRP 275
Query: 397 P------PPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSP---PENPGQ 447
PPPPPQ P P PSAS P PPP + P LP S E P
Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPR-PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334
Query: 448 PSMGIDIASA-PALQQYRTSA--GSPANQSPTSPVSNQGFSPGSSP 490
P + ++S+ P L S P ++ P PV + G P
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLP 380
Score = 53.9 bits (128), Expect = 5e-07
Identities = 50/174 (28%), Positives = 70/174 (40%), Gaps = 21/174 (12%)
Query: 314 STPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQ--QLPYAFF 371
+ P PQ+ V P + A Q P P P + + ++ +LP
Sbjct: 281 AVPPPPPQNNKPPV-PSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL 339
Query: 372 TQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAV 431
+ + S P P P P PP + PPP PVR PPG GP PPP V
Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPP-----PVRDPPG---------RSGPLPPPPPV 385
Query: 432 TVPSSLPQSPPENPGQPS-MGIDIASA---PALQQYRTSAGSPANQSPTSPVSN 481
+ S ++ P P PS G+D + P L R SAG+P P++ + N
Sbjct: 386 SRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRN 439
Score = 50.4 bits (119), Expect = 5e-06
Identities = 53/198 (26%), Positives = 71/198 (35%), Gaps = 25/198 (12%)
Query: 218 QAWDTKKTGSRPKSCEVPGIN--IFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLP 275
+A D K P P I+ P +N +P+T S P P P
Sbjct: 258 RALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASS------QAPPPPP 311
Query: 276 TPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSS------PQHRPAGVSP 329
P P P P SSS + +L + + + +PG S P RP P
Sbjct: 312 PPSRPGPPPLPP-SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP----P 366
Query: 330 LSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPP 389
+ R P P+S AL QLP +++G P P+PP PP
Sbjct: 367 PPVRDPPGRSGPLPPPPPVS--RNGSTSRALPATPQLP----SRSGVDSPRSGPRPPLPP 420
Query: 390 PPASQQPPPPPPPQAPVR 407
S PPPPPP +R
Sbjct: 421 DRPSAGAPPPPPPSTSIR 438
Score = 49.3 bits (116), Expect = 1e-05
Identities = 55/210 (26%), Positives = 71/210 (33%), Gaps = 58/210 (27%)
Query: 260 GSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSS 319
G+ P + P P P P P+ P S+SS + P
Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQ--------------------APPPPP 311
Query: 320 PQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLP-YAFFTQAGSQQ 378
P RP G PL S+ + T + LSL P ++G
Sbjct: 312 PPSRP-GPPPLPPSSSGNDE------------TPRLPQRNLSLSSSTPPLPSPGRSGPLP 358
Query: 379 PPPQPQPPPP---PPPASQQPPPPPP--------------PQAPVRLP-------PGGPL 414
PPP +PPPP PP S PPPPP PQ P R P PL
Sbjct: 359 PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL 418
Query: 415 LPSASLTRGPQPPPLAVTVPSSLPQSPPEN 444
P P PPP + ++ + SP E+
Sbjct: 419 PPDRPSAGAPPPPPPSTSIRNGFQDSPCED 448
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.4 bits (150), Expect = 1e-09
Identities = 77/286 (26%), Positives = 104/286 (36%), Gaps = 33/286 (11%)
Query: 235 PGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPT--FPALSSSS 292
PG+ A + +++GGS P L S P P FP S
Sbjct: 98 PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH 157
Query: 293 STGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEAR---------RQQASP 343
+G + G S P S P P+ P+ S R RQ +
Sbjct: 158 RSGPPEPQRNRMPPPRPDVG-SKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPG 216
Query: 344 TLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQP-PPQP------QPPPPPPPASQQP 396
P P + A+ S+ Q P + + ++ P PP P +PPPPPPP +P
Sbjct: 217 PTPPPFPGNRGTALGGGSIRQS-PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRP 275
Query: 397 P------PPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSP---PENPGQ 447
PPPPPQ P P PSAS P PPP + P LP S E P
Sbjct: 276 SIHREAVPPPPPQNNKPPVPSTPR-PSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRL 334
Query: 448 PSMGIDIASA-PALQQYRTSA--GSPANQSPTSPVSNQGFSPGSSP 490
P + ++S+ P L S P ++ P PV + G P
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLP 380
Score = 53.9 bits (128), Expect = 5e-07
Identities = 50/174 (28%), Positives = 70/174 (40%), Gaps = 21/174 (12%)
Query: 314 STPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQ--QLPYAFF 371
+ P PQ+ V P + A Q P P P + + ++ +LP
Sbjct: 281 AVPPPPPQNNKPPV-PSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL 339
Query: 372 TQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAV 431
+ + S P P P P PP + PPP PVR PPG GP PPP V
Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPP-----PVRDPPG---------RSGPLPPPPPV 385
Query: 432 TVPSSLPQSPPENPGQPS-MGIDIASA---PALQQYRTSAGSPANQSPTSPVSN 481
+ S ++ P P PS G+D + P L R SAG+P P++ + N
Sbjct: 386 SRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRN 439
Score = 50.4 bits (119), Expect = 5e-06
Identities = 53/198 (26%), Positives = 71/198 (35%), Gaps = 25/198 (12%)
Query: 218 QAWDTKKTGSRPKSCEVPGIN--IFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLP 275
+A D K P P I+ P +N +P+T S P P P
Sbjct: 258 RALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASS------QAPPPPP 311
Query: 276 TPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSS------PQHRPAGVSP 329
P P P P SSS + +L + + + +PG S P RP P
Sbjct: 312 PPSRPGPPPLPP-SSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP----P 366
Query: 330 LSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPP 389
+ R P P+S AL QLP +++G P P+PP PP
Sbjct: 367 PPVRDPPGRSGPLPPPPPVS--RNGSTSRALPATPQLP----SRSGVDSPRSGPRPPLPP 420
Query: 390 PPASQQPPPPPPPQAPVR 407
S PPPPPP +R
Sbjct: 421 DRPSAGAPPPPPPSTSIR 438
Score = 49.3 bits (116), Expect = 1e-05
Identities = 55/210 (26%), Positives = 71/210 (33%), Gaps = 58/210 (27%)
Query: 260 GSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSS 319
G+ P + P P P P P+ P S+SS + P
Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQ--------------------APPPPP 311
Query: 320 PQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLP-YAFFTQAGSQQ 378
P RP G PL S+ + T + LSL P ++G
Sbjct: 312 PPSRP-GPPPLPPSSSGNDE------------TPRLPQRNLSLSSSTPPLPSPGRSGPLP 358
Query: 379 PPPQPQPPPP---PPPASQQPPPPPP--------------PQAPVRLP-------PGGPL 414
PPP +PPPP PP S PPPPP PQ P R P PL
Sbjct: 359 PPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL 418
Query: 415 LPSASLTRGPQPPPLAVTVPSSLPQSPPEN 444
P P PPP + ++ + SP E+
Sbjct: 419 PPDRPSAGAPPPPPPSTSIRNGFQDSPCED 448
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 62.4 bits (150), Expect = 1e-09
Identities = 33/65 (50%), Positives = 37/65 (56%), Gaps = 7/65 (10%)
Query: 377 QQPPPQPQPPPPPPPASQQPPPPPPPQAP--VRLPPG--GPLLPSASL---TRGPQPPPL 429
Q PPP P PPPPPPP PPPPPPP AP V+LP PL PS + PP L
Sbjct: 1991 QAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQL 2050
Query: 430 AVTVP 434
A+ +P
Sbjct: 2051 ALQLP 2055
Score = 49.7 bits (117), Expect = 8e-06
Identities = 54/203 (26%), Positives = 74/203 (36%), Gaps = 29/203 (14%)
Query: 380 PPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPL-LPSASLTRGPQPPPLAVTVPSSLP 438
P P+ PPPPPP PPP P AP + GP+ +P+ T PPP P P
Sbjct: 1952 PSSPETPPPPPP------PPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP 2005
Query: 439 QSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQS-PTSPVSNQGFSPGSSPQHTSTLG 497
PP P P SAP Q S P S PV + P PQ L
Sbjct: 2006 PPPPPPPPPP------PSAPPQVQLPVSLDLPLFPSIMMQPVQH----PALPPQLALQL- 2054
Query: 498 SVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGSH 557
QM A A+ +Q + N + S P + + Q ++
Sbjct: 2055 ---------PQMDALSADLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDI 2105
Query: 558 GSLPDSQQL-GYASHSGIPNIIL 579
+ P +Q+ A SG+ ++
Sbjct: 2106 NNSPSEEQIQEMAEKSGLSQKVI 2128
Score = 47.0 bits (110), Expect = 6e-05
Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 6/101 (5%)
Query: 356 AMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQA--PVRLPPGGP 413
A++ + + + Y P P PPPPPP PP PP P + PV++P
Sbjct: 1932 ALEKFARQYREAYDKLYPISPSSPETPPPPPPPPP----LPPAPPQPSSMGPVKIPNTVS 1987
Query: 414 LLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDI 454
A P PPP P P PP P Q + + +
Sbjct: 1988 TPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSL 2028
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/81 (37%), Positives = 33/81 (40%), Gaps = 25/81 (30%)
Query: 379 PPPQPQ-PPPPPPPASQQP-----------------PPPPPPQAPVRLPPGGPLLPSASL 420
PPP P PP PP P+S P PPPPPP P PP P PSA
Sbjct: 1961 PPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSA-- 2018
Query: 421 TRGPQPPPLAVTVPSSLPQSP 441
PP + + V LP P
Sbjct: 2019 -----PPQVQLPVSLDLPLFP 2034
Score = 44.3 bits (103), Expect = 4e-04
Identities = 38/102 (37%), Positives = 46/102 (45%), Gaps = 15/102 (14%)
Query: 309 AGQGMSTPG-SSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLP 367
+G G STP SP+ P SP + +Q+ P SP S T+ A+ S P
Sbjct: 2338 SGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDP--SPPSQGTKP-ALPLASTSSDPP 2394
Query: 368 YAFFTQAGSQQPPPQPQPPPPP------PPASQQPPPPPPPQ 403
QA + QP PQPQPP P P ASQ P P P Q
Sbjct: 2395 -----QASTAQPQPQPQPPKQPQLIGRPPSASQTPVPSSPLQ 2431
Score = 38.5 bits (88), Expect = 0.020
Identities = 37/113 (32%), Positives = 46/113 (40%), Gaps = 22/113 (19%)
Query: 286 PALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTL 345
P + SSS ++ + G+ PG P P P SL Q S TL
Sbjct: 3036 PGMMDSSSLHGISLPTAYPGL---------PGLPPVLLPGMNGPSSLPGFP---QNSNTL 3083
Query: 346 SP-----LSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPAS 393
+P L T A + ALSL T+ Q PPP P PPPPPP +S
Sbjct: 3084 TPPGAGMLGFPTSATSSPALSLSSAP-----TKPLLQTPPPPPPPPPPPPSSS 3131
Score = 37.0 bits (84), Expect = 0.057
Identities = 30/96 (31%), Positives = 38/96 (39%), Gaps = 10/96 (10%)
Query: 385 PPPPPPPASQQPPPPPPPQAPVRLPPGGP---LLPSASLTRGPQPPPLAVTVPSSLPQSP 441
P P P P P P P + P + P P P+ L PP A T + PQ
Sbjct: 2348 PSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQAST---AQPQPQ 2404
Query: 442 PENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTS 477
P+ P QP + I P+ Q + SP S TS
Sbjct: 2405 PQPPKQPQL---IGRPPSASQTPVPS-SPLQISMTS 2436
Score = 34.3 bits (77), Expect = 0.37
Identities = 32/102 (31%), Positives = 42/102 (41%), Gaps = 18/102 (17%)
Query: 381 PQPQPPPPPPPASQQPPPPPPPQAPVRLPPGG--PLLPSASLTRG------------PQP 426
P P+P P + P P Q+ P G P LP AS + PQP
Sbjct: 2348 PSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQP 2407
Query: 427 P--PLAVTVPSSLPQSP-PENPGQPSM-GIDIASAPALQQYR 464
P P + P S Q+P P +P Q SM + + P L QY+
Sbjct: 2408 PKQPQLIGRPPSASQTPVPSSPLQISMTSLQNSLPPQLLQYQ 2449
Score = 31.6 bits (70), Expect = 2.4
Identities = 14/27 (51%), Positives = 14/27 (51%), Gaps = 3/27 (11%)
Query: 388 PPPPASQQPPPPPPPQAPVRLPPGGPL 414
P P Q PPPPPPP P PP L
Sbjct: 3109 PTKPLLQTPPPPPPPPPP---PPSSSL 3132
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 62.4 bits (150), Expect = 1e-09
Identities = 47/160 (29%), Positives = 61/160 (38%), Gaps = 46/160 (28%)
Query: 335 EARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQ 394
E+ + + + PLSP + V PY SQ PP P PPPPPPP
Sbjct: 596 ESMNRPYTSLVPPLSPQPKIVT----------PYT-----ASQPSPPLPPPPPPPPPPPP 640
Query: 395 QPPPPPPPQAPVRLPPGGPLLP-----------------SASLTRGPQPP--------PL 429
PPPPPPP P G P S +L + P PP P
Sbjct: 641 PPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQ 700
Query: 430 AVTVPSSLPQSPPENPGQPSMGIDIAS------APALQQY 463
+ P+ + PP P P+ G +A AP+L Q+
Sbjct: 701 ILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQF 740
Score = 60.8 bits (146), Expect = 4e-09
Identities = 65/218 (29%), Positives = 88/218 (40%), Gaps = 43/218 (19%)
Query: 271 PSPLPTPLDPEEPTFPALS--SSSSTGNLAANLTHLG-------IGGAGQGMSTPGS--- 318
P P+P PL P+ P P ++ + +ST +A +T + A + + P S
Sbjct: 766 PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP 825
Query: 319 -SPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDAL---------SLEQQLPY 368
SP P V P +L + + A P SPLSP+ V A ++E Q
Sbjct: 826 PSPPTPPVPVPPPTLPKQ-QSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLK 884
Query: 369 AFFTQAGSQQPP---------------PQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGP 413
Q PP P P PPPPP +S PPPPP +PV PP P
Sbjct: 885 PVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP--SPVPAPPPPP 942
Query: 414 LLPSASLTRGPQPPPLAVTVPSSLP--QSPPENPGQPS 449
P+AS T P T +S P + PP P + S
Sbjct: 943 -PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNS 979
Score = 52.4 bits (124), Expect = 1e-06
Identities = 59/228 (25%), Positives = 75/228 (32%), Gaps = 47/228 (20%)
Query: 271 PSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPL 330
P P P P P P P L S S+P A +
Sbjct: 632 PPPPPPPPPPPPPPPPPLPSQ--------------------------SAPSAGSAAPMFV 665
Query: 331 SLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPP 390
ST R Q AS L M + S++ Q+ PPP P PPPP P
Sbjct: 666 KYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQI----LVPPNGVVPPPPPPPPPPTP 721
Query: 391 PA--SQQPPPPPPPQAPVRLPPGGPL-------LPSASLTRGPQPPPLAVTVPSSLPQSP 441
+ +Q P P P P P PL + + P PPP+ +P PQ+P
Sbjct: 722 GSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP---PQAP 778
Query: 442 PENPGQPSMGIDI-ASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGS 488
P +P + I S + T A P P P Q P S
Sbjct: 779 P----KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS 822
Score = 49.7 bits (117), Expect = 8e-06
Identities = 63/234 (26%), Positives = 83/234 (35%), Gaps = 35/234 (14%)
Query: 271 PSPLPTPLDPEEPTFPALSSSSSTGNLA------ANLTHLGIGGAGQG-MSTPGSSPQHR 323
P P P P P P P+ S+ S G+ A + +T L G + P + P +
Sbjct: 635 PPPPPPPPPPPPPPLPS-QSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQ 693
Query: 324 PAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPP-- 381
V P L P P P T AM L + P A S PPP
Sbjct: 694 SQSVKPQILVPP--NGVVPPPPPPPPPPTPGSAMAQL---KPAPCAPSLPQFSAPPPPLK 748
Query: 382 ----------QPQPPPPPPPASQQPPPPPPPQAPVRLPPG------GPLLPSASLTRGPQ 425
P PPPPPP PP PP+ V +P P++ A+
Sbjct: 749 IHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP 808
Query: 426 PPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPV 479
P P A P+ P +P P + + + P Q + A P SP SPV
Sbjct: 809 PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSF--CAKPP--PSPLSPV 858
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/151 (32%), Positives = 61/151 (40%), Gaps = 23/151 (15%)
Query: 339 QQASPTLSPLSPITQAVAMDALS---LEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQ 395
Q A PT P PI + A + P + T A P P PP PPA +Q
Sbjct: 757 QVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQ 816
Query: 396 P-------PPPPPPQAPVRLPPGGPLLP-SASLTRGPQPPPLAVTVPSSLPQSPPENPGQ 447
P P P PP PV +PP P LP S P P PL+ VPS + Q + P
Sbjct: 817 PAFPASYIP-PSPPTPPVPVPP--PTLPKQQSFCAKPPPSPLS-PVPSVVKQIASQFPPP 872
Query: 448 PSMGIDIASAPALQQYRTSAGSPANQSPTSP 478
P+ P + + PAN +P SP
Sbjct: 873 PT--------PPAMESQPLKPVPANVAPQSP 895
Score = 44.3 bits (103), Expect = 4e-04
Identities = 57/239 (23%), Positives = 83/239 (34%), Gaps = 28/239 (11%)
Query: 271 PSPLPTPLDPEEPTF-PALSSSSSTGNLAANLTHLG--------IGGAGQGMSTPGSSPQ 321
PSP+P P P PT P S S G + + G + S+ P+
Sbjct: 932 PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPE 991
Query: 322 HRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQ-QLPYAFFTQAGSQQPP 380
+ V L + SP+ L P L+L LP S + P
Sbjct: 992 PKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051
Query: 381 P-----QPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPS 435
+ P P S PPPPP+ + LPP + ++ G P +AV P
Sbjct: 1052 VLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPP----IEIPAVFSGNTSPKVAVVNPQ 1107
Query: 436 -------SLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPG 487
S+ ++PP P +P A + + + Q PTSP S+ PG
Sbjct: 1108 PQQWSKMSVKKAPP--PTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPG 1164
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 62.4 bits (150), Expect = 1e-09
Identities = 65/243 (26%), Positives = 91/243 (37%), Gaps = 22/243 (9%)
Query: 271 PSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPL 330
PS PT + ++ L S L+A HL + + + P P PA +P+
Sbjct: 683 PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPP---PAQDPAPATPV 739
Query: 331 S----LSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPP 386
+ L +A QASP +P P + S LP+ P P P P
Sbjct: 740 AKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP 799
Query: 387 PPPPPASQQP---PPPPPPQAPVRLPPGGPLLPSASLTRGP--QPPPLAVTVPSSL-PQS 440
P PP+ Q PP PP P P P LP + + PPP + P++ P
Sbjct: 800 PSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQ 859
Query: 441 PPENP-GQPSMGIDIASAPALQQYRTSAGSPANQ-------SPTSPVSNQGFSPGSSPQH 492
PP P QP G + AP L TS+ ++ +PT F P P
Sbjct: 860 PPLRPQSQPPEG-PLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHK 918
Query: 493 TST 495
+ T
Sbjct: 919 SPT 921
Score = 48.1 bits (113), Expect = 2e-05
Identities = 79/266 (29%), Positives = 92/266 (34%), Gaps = 57/266 (21%)
Query: 272 SPLPTPLDPEEPTF--PALSSSSSTGNLA--ANLTHLGIGGAGQGMSTPGSSPQH--RPA 325
SP P P P P SSS S + A + HL + S P S PQ RP
Sbjct: 755 SPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPP 814
Query: 326 GVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPP--PQP 383
PL QA PTL + V + L + T G QPP PQ
Sbjct: 815 SEPPLH---PCPPPQAPPTLPGIF-----VIQNQLGVPPPASNPAPTAPGPPQPPLRPQS 866
Query: 384 QPPPPP-PPASQQPPPP---------------------------PPPQAPVRLPPGGPLL 415
QPP P PPA PP PP Q P + P P L
Sbjct: 867 QPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTL 926
Query: 416 PSASLTRGPQPPP----LAVTVP-SSLPQSPP--ENPGQPSMGIDIAS----APALQQYR 464
P PPP VT P +LPQ E Q GI + + APA Q
Sbjct: 927 HLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTS 986
Query: 465 TSAGSPANQSPTSPVSNQGFSPGSSP 490
TS G SP + V G +P +P
Sbjct: 987 TSLGPLT--SPAASVLVSGQAPSGTP 1010
Score = 47.4 bits (111), Expect = 4e-05
Identities = 82/298 (27%), Positives = 119/298 (39%), Gaps = 60/298 (20%)
Query: 251 LIPATHNTGGSL---PDLTNIHFPSPLP-------------------TPLDPEEPTFPAL 288
L A +TGG L P LTN + PL P+ +P +
Sbjct: 498 LAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQM 557
Query: 289 SSSSSTGNLAANLTHLGIGGAG----QGMSTPGSSPQ--HRPAG-VSPLSLSTEARRQQA 341
S + G+L G A QG++ P S+ + P G V P + + A +A
Sbjct: 558 PVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPA--AATGEA 615
Query: 342 SPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPP 401
+P L+ + P QA ++ LP Q +QQPP P P PP + P P P
Sbjct: 616 APVLT-VQPAPQAPP----AVSTPLPLGL-QQPQAQQPPQAPTPQAAAPPQATTPQPSPG 669
Query: 402 -PQAPVRLPPGGP--LLPSASLTRG------PQP---PPLA-----VTVPSSLPQSPPEN 444
+P ++ G P P+A LT+ PQ PL+ ++VP+S+ S P
Sbjct: 670 LASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPP 729
Query: 445 PGQPSMGIDIASAPAL-QQYRTSAGSPANQSPTSPVSN--QGFSPGSSPQ--HTSTLG 497
P+ +A L Q S SPA +P P + +G P SSP H + LG
Sbjct: 730 AQDPAPATPVAKGAGLGPQAPDSQASPA-PAPQIPAAAPLKGPGPSSSPSLPHQAPLG 786
Score = 47.4 bits (111), Expect = 4e-05
Identities = 94/398 (23%), Positives = 142/398 (35%), Gaps = 58/398 (14%)
Query: 205 EETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGS--- 261
E+TT DK L+K+ D + SR G+ I S++ P + + G+
Sbjct: 1183 EKTTLALDKQLAKEKPDEYVSSSRSL-----GLPIAASSEGHRLPGHGPLSSSAPGASTQ 1237
Query: 262 ----LPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTPG 317
LP I +P +LSSSSS+ + A++L G P
Sbjct: 1238 PPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPI 1297
Query: 318 SSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQ 377
+ + R L + EA LS + A+D + P
Sbjct: 1298 KTYEARSRIGLKLKIKQEAG----------LSKVVHNTALDPVHQPPPPPATLKVA---- 1343
Query: 378 QPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPG-GPLLPSASLTRGPQPPPLAVTVPSS 436
+PPP+P PPPPP PPP AP R P G P P PL T +
Sbjct: 1344 EPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRL---------PLRKTYREN 1394
Query: 437 L--PQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTS 494
+ P +P P + G A PA TS G + Q G P+ +
Sbjct: 1395 VGGPGAPEGTPAGRARGGSPAPLPAKVDEATS-GLIRELAAVEDELYQRMLKGPPPEPAA 1453
Query: 495 TLGSVFGDAYYEQQ--MAARQANALSHQLEQFNM-------------MENAISS--SSLY 537
+ GD +E A++ + S ++Q + +++AI S +
Sbjct: 1454 SAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQ 1513
Query: 538 SPGST--LNYSQAAMMGLTGSHGSLPDSQQLGYASHSG 573
+PG T +Y AA G S L + +SH+G
Sbjct: 1514 APGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNG 1551
Score = 31.2 bits (69), Expect = 3.1
Identities = 59/237 (24%), Positives = 74/237 (31%), Gaps = 45/237 (18%)
Query: 235 PGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSST 294
P N P+A L P + G LP P P P T A++SSS T
Sbjct: 846 PASNPAPTAPGPPQPPLRPQSQPPEGPLP-----------PAPHLPPSSTSSAVASSSET 894
Query: 295 GNLAANLTHLGIGGAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASP------TLSPL 348
+ T Q P P P L L E P +P
Sbjct: 895 SSRLPAPTPSDF----QLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950
Query: 349 SPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQP-----PPPPPPAS-----QQPPP 398
+ Q A+ L Q+P Q + P PQ P P AS Q P
Sbjct: 951 PALPQPKAL--LERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSG 1008
Query: 399 PP------PPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPS 449
P P AP+ PLLP+ + P L V +S PG+PS
Sbjct: 1009 TPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAAS------SGPGKPS 1059
>gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
Length = 1062
Score = 62.4 bits (150), Expect = 1e-09
Identities = 66/237 (27%), Positives = 91/237 (38%), Gaps = 37/237 (15%)
Query: 225 TGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPT 284
+GS P++ +PSA+Q AL H + + H P P TP + +
Sbjct: 827 SGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQS 886
Query: 285 FPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGS---SPQHRPAGVSPLSLSTEARRQQA 341
A + S + A HLG G Q + PG+ +P P G S
Sbjct: 887 QHA--APSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPS------------- 931
Query: 342 SPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPP 401
SP S Q A+ A+ QQLP+ F A Q Q PPP P P P
Sbjct: 932 --AQSPQSSFPQPAAVYAIH-HQQLPHGFTNMAHVTQAHVQTGITAAPPP---HPGAPHP 985
Query: 402 PQAPVRLPP---GGPLLPSASLTRGPQPPPLAVTVPSSLP-------QSPPENPGQP 448
PQ + PP GGP P ++ + P L+ + PS P + P + PG P
Sbjct: 986 PQVMLLHPPQSHGGP--PQGAVPQS-GVPALSASTPSPYPYIGHPQGEQPGQAPGFP 1039
Score = 41.6 bits (96), Expect = 0.002
Identities = 38/108 (35%), Positives = 47/108 (43%), Gaps = 16/108 (14%)
Query: 382 QPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSP 441
+PQP P SQ PPP QA R PPGG P+ L P PLA S+ P P
Sbjct: 3 KPQPLQQP---SQPQQPPPTQQAVARRPPGGTSPPNGGL-----PGPLAT---SAAPPGP 51
Query: 442 PENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSS 489
P P +G A+ L+ R + G A Q P P PG++
Sbjct: 52 PA-AASPCLGPVAAAGSGLR--RGAEGILAPQPP--PPQQHQERPGAA 94
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/99 (34%), Positives = 37/99 (37%), Gaps = 34/99 (34%)
Query: 378 QPPPQPQPPPPP-------PPASQQPPPP--PPPQAPVRLPPGGPLLPS----------A 418
Q P QPQ PPP PP PP P P A PPG P S +
Sbjct: 8 QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
Query: 419 SLTRG------PQPPPLAVTVPSSLPQSPPENPGQPSMG 451
L RG PQPPP PQ E PG ++G
Sbjct: 68 GLRRGAEGILAPQPPP---------PQQHQERPGAAAIG 97
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/146 (28%), Positives = 62/146 (42%), Gaps = 15/146 (10%)
Query: 367 PYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQP 426
P + T++ S + P P +QPPPP P Q PP G L+ G
Sbjct: 595 PVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ--TGSPPVG-LIKGEDKDEG--- 648
Query: 427 PPLAVTVPSSL--PQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGF 484
P+A V S P + NP +P + ++ +++ TS G + +P+ PV G
Sbjct: 649 -PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP-----TSPGPRTHSTPSIPVLTAGQ 702
Query: 485 SPGSSPQHTSTLGSV-FGDAYYEQQM 509
S SPQ+ S + + G A QM
Sbjct: 703 SGLYSPQYISYIPQIHMGPAVQAPQM 728
Score = 40.8 bits (94), Expect = 0.004
Identities = 67/287 (23%), Positives = 102/287 (35%), Gaps = 40/287 (13%)
Query: 241 PSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEE---PTFPALSSSSS---T 294
P A+Q + L P + P L +++ + PT P P+ P L++ S +
Sbjct: 649 PVAEQVKKSTLNPNAKEFNPTKP-LLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYS 707
Query: 295 GNLAANLTHLGIGGAGQGM---------STPGSSPQHRPAGVSPLSLSTEARRQQASPTL 345
+ + + +G A Q S PG ++R A S R Q P
Sbjct: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS----LPPQRSDQHQPAS 763
Query: 346 SPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAP 405
+P P+ QA A L PY+ + QQ P QP P QP P Q+
Sbjct: 764 AP--PMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSN 821
Query: 406 VRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRT 465
R+ LT G P + V SS PQ P P + + + T
Sbjct: 822 PRM-----------LTSGSHPQAI---VSSSTPQYPSAEQPTP-QALYATVHQSYPHHAT 866
Query: 466 SAGSPANQSPTSPVSNQGFSPGSSP---QHTSTLGSVFGDAYYEQQM 509
+ Q T+P +Q S ++P QH + G +Q +
Sbjct: 867 QLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNL 913
Score = 33.5 bits (75), Expect = 0.63
Identities = 39/169 (23%), Positives = 56/169 (33%), Gaps = 26/169 (15%)
Query: 308 GAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLP 367
G G+S+ H SP +EAR P S +SP Q A +L
Sbjct: 371 GGRPGLSSLPPRGPHHLDNSSP-GPGSEARGINGGP--SRMSPKAQRPLRGAKTLSSP-- 425
Query: 368 YAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPP 427
S +P + PPPP PP P AP + P P
Sbjct: 426 --------SNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP------------EP 465
Query: 428 PLAVTVPSSLPQSP-PENPGQPSMGIDIASAPALQQYRTSAGSPANQSP 475
P+ VP+S P + P +G ++P + T + + P
Sbjct: 466 PIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEP 514
>gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]
Length = 1044
Score = 62.4 bits (150), Expect = 1e-09
Identities = 66/234 (28%), Positives = 91/234 (38%), Gaps = 35/234 (14%)
Query: 225 TGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPT 284
+GS P++ +PSA+Q AL H + + H P P TP + +
Sbjct: 827 SGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQS 886
Query: 285 FPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGS---SPQHRPAGVSPLSLSTEARRQQA 341
A + S + A HLG G Q + PG+ +P P G S
Sbjct: 887 QHA--APSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPS------------- 931
Query: 342 SPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPP 401
SP S Q A+ A+ QQLP+ F A Q Q PPP P P P
Sbjct: 932 --AQSPQSSFPQPAAVYAIH-HQQLPHGFTNMAHVTQAHVQTGITAAPPP---HPGAPHP 985
Query: 402 PQAPVRLPP---GGPLLPSASLTRGPQPPPLAVTVPSSL-----PQSPPENPGQ 447
PQ + PP GGP P ++ + P L+ + PS PQ+P PG+
Sbjct: 986 PQVMLLHPPQSHGGP--PQGAVPQS-GVPALSASTPSPYPYIGHPQAPLPPPGE 1036
Score = 41.6 bits (96), Expect = 0.002
Identities = 38/108 (35%), Positives = 47/108 (43%), Gaps = 16/108 (14%)
Query: 382 QPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSP 441
+PQP P SQ PPP QA R PPGG P+ L P PLA S+ P P
Sbjct: 3 KPQPLQQP---SQPQQPPPTQQAVARRPPGGTSPPNGGL-----PGPLAT---SAAPPGP 51
Query: 442 PENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSS 489
P P +G A+ L+ R + G A Q P P PG++
Sbjct: 52 PA-AASPCLGPVAAAGSGLR--RGAEGILAPQPP--PPQQHQERPGAA 94
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/99 (34%), Positives = 37/99 (37%), Gaps = 34/99 (34%)
Query: 378 QPPPQPQPPPPP-------PPASQQPPPP--PPPQAPVRLPPGGPLLPS----------A 418
Q P QPQ PPP PP PP P P A PPG P S +
Sbjct: 8 QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
Query: 419 SLTRG------PQPPPLAVTVPSSLPQSPPENPGQPSMG 451
L RG PQPPP PQ E PG ++G
Sbjct: 68 GLRRGAEGILAPQPPP---------PQQHQERPGAAAIG 97
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/146 (28%), Positives = 62/146 (42%), Gaps = 15/146 (10%)
Query: 367 PYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQP 426
P + T++ S + P P +QPPPP P Q PP G L+ G
Sbjct: 595 PVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ--TGSPPVG-LIKGEDKDEG--- 648
Query: 427 PPLAVTVPSSL--PQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGF 484
P+A V S P + NP +P + ++ +++ TS G + +P+ PV G
Sbjct: 649 -PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP-----TSPGPRTHSTPSIPVLTAGQ 702
Query: 485 SPGSSPQHTSTLGSV-FGDAYYEQQM 509
S SPQ+ S + + G A QM
Sbjct: 703 SGLYSPQYISYIPQIHMGPAVQAPQM 728
Score = 40.8 bits (94), Expect = 0.004
Identities = 67/287 (23%), Positives = 102/287 (35%), Gaps = 40/287 (13%)
Query: 241 PSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEE---PTFPALSSSSS---T 294
P A+Q + L P + P L +++ + PT P P+ P L++ S +
Sbjct: 649 PVAEQVKKSTLNPNAKEFNPTKP-LLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYS 707
Query: 295 GNLAANLTHLGIGGAGQGM---------STPGSSPQHRPAGVSPLSLSTEARRQQASPTL 345
+ + + +G A Q S PG ++R A S R Q P
Sbjct: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS----LPPQRSDQHQPAS 763
Query: 346 SPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAP 405
+P P+ QA A L PY+ + QQ P QP P QP P Q+
Sbjct: 764 AP--PMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSN 821
Query: 406 VRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRT 465
R+ LT G P + V SS PQ P P + + + T
Sbjct: 822 PRM-----------LTSGSHPQAI---VSSSTPQYPSAEQPTP-QALYATVHQSYPHHAT 866
Query: 466 SAGSPANQSPTSPVSNQGFSPGSSP---QHTSTLGSVFGDAYYEQQM 509
+ Q T+P +Q S ++P QH + G +Q +
Sbjct: 867 QLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNL 913
Score = 33.5 bits (75), Expect = 0.63
Identities = 39/169 (23%), Positives = 56/169 (33%), Gaps = 26/169 (15%)
Query: 308 GAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLP 367
G G+S+ H SP +EAR P S +SP Q A +L
Sbjct: 371 GGRPGLSSLPPRGPHHLDNSSP-GPGSEARGINGGP--SRMSPKAQRPLRGAKTLSSP-- 425
Query: 368 YAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPP 427
S +P + PPPP PP P AP + P P
Sbjct: 426 --------SNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP------------EP 465
Query: 428 PLAVTVPSSLPQSP-PENPGQPSMGIDIASAPALQQYRTSAGSPANQSP 475
P+ VP+S P + P +G ++P + T + + P
Sbjct: 466 PIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEP 514
>gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]
Length = 1097
Score = 62.4 bits (150), Expect = 1e-09
Identities = 66/237 (27%), Positives = 91/237 (38%), Gaps = 37/237 (15%)
Query: 225 TGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEPT 284
+GS P++ +PSA+Q AL H + + H P P TP + +
Sbjct: 827 SGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQS 886
Query: 285 FPALSSSSSTGNLAANLTHLGIGGAGQGMSTPGS---SPQHRPAGVSPLSLSTEARRQQA 341
A + S + A HLG G Q + PG+ +P P G S
Sbjct: 887 QHA--APSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPS------------- 931
Query: 342 SPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPP 401
SP S Q A+ A+ QQLP+ F A Q Q PPP P P P
Sbjct: 932 --AQSPQSSFPQPAAVYAIH-HQQLPHGFTNMAHVTQAHVQTGITAAPPP---HPGAPHP 985
Query: 402 PQAPVRLPP---GGPLLPSASLTRGPQPPPLAVTVPSSLP-------QSPPENPGQP 448
PQ + PP GGP P ++ + P L+ + PS P + P + PG P
Sbjct: 986 PQVMLLHPPQSHGGP--PQGAVPQS-GVPALSASTPSPYPYIGHPQGEQPGQAPGFP 1039
Score = 41.6 bits (96), Expect = 0.002
Identities = 38/108 (35%), Positives = 47/108 (43%), Gaps = 16/108 (14%)
Query: 382 QPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSP 441
+PQP P SQ PPP QA R PPGG P+ L P PLA S+ P P
Sbjct: 3 KPQPLQQP---SQPQQPPPTQQAVARRPPGGTSPPNGGL-----PGPLAT---SAAPPGP 51
Query: 442 PENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSS 489
P P +G A+ L+ R + G A Q P P PG++
Sbjct: 52 PA-AASPCLGPVAAAGSGLR--RGAEGILAPQPP--PPQQHQERPGAA 94
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/99 (34%), Positives = 37/99 (37%), Gaps = 34/99 (34%)
Query: 378 QPPPQPQPPPPP-------PPASQQPPPP--PPPQAPVRLPPGGPLLPS----------A 418
Q P QPQ PPP PP PP P P A PPG P S +
Sbjct: 8 QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
Query: 419 SLTRG------PQPPPLAVTVPSSLPQSPPENPGQPSMG 451
L RG PQPPP PQ E PG ++G
Sbjct: 68 GLRRGAEGILAPQPPP---------PQQHQERPGAAAIG 97
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/146 (28%), Positives = 62/146 (42%), Gaps = 15/146 (10%)
Query: 367 PYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQP 426
P + T++ S + P P +QPPPP P Q PP G L+ G
Sbjct: 595 PVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ--TGSPPVG-LIKGEDKDEG--- 648
Query: 427 PPLAVTVPSSL--PQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGF 484
P+A V S P + NP +P + ++ +++ TS G + +P+ PV G
Sbjct: 649 -PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP-----TSPGPRTHSTPSIPVLTAGQ 702
Query: 485 SPGSSPQHTSTLGSV-FGDAYYEQQM 509
S SPQ+ S + + G A QM
Sbjct: 703 SGLYSPQYISYIPQIHMGPAVQAPQM 728
Score = 40.8 bits (94), Expect = 0.004
Identities = 67/287 (23%), Positives = 102/287 (35%), Gaps = 40/287 (13%)
Query: 241 PSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEE---PTFPALSSSSS---T 294
P A+Q + L P + P L +++ + PT P P+ P L++ S +
Sbjct: 649 PVAEQVKKSTLNPNAKEFNPTKP-LLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYS 707
Query: 295 GNLAANLTHLGIGGAGQGM---------STPGSSPQHRPAGVSPLSLSTEARRQQASPTL 345
+ + + +G A Q S PG ++R A S R Q P
Sbjct: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS----LPPQRSDQHQPAS 763
Query: 346 SPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAP 405
+P P+ QA A L PY+ + QQ P QP P QP P Q+
Sbjct: 764 AP--PMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSN 821
Query: 406 VRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRT 465
R+ LT G P + V SS PQ P P + + + T
Sbjct: 822 PRM-----------LTSGSHPQAI---VSSSTPQYPSAEQPTP-QALYATVHQSYPHHAT 866
Query: 466 SAGSPANQSPTSPVSNQGFSPGSSP---QHTSTLGSVFGDAYYEQQM 509
+ Q T+P +Q S ++P QH + G +Q +
Sbjct: 867 QLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNL 913
Score = 33.5 bits (75), Expect = 0.63
Identities = 39/169 (23%), Positives = 56/169 (33%), Gaps = 26/169 (15%)
Query: 308 GAGQGMSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLP 367
G G+S+ H SP +EAR P S +SP Q A +L
Sbjct: 371 GGRPGLSSLPPRGPHHLDNSSP-GPGSEARGINGGP--SRMSPKAQRPLRGAKTLSSP-- 425
Query: 368 YAFFTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPP 427
S +P + PPPP PP P AP + P P
Sbjct: 426 --------SNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP------------EP 465
Query: 428 PLAVTVPSSLPQSP-PENPGQPSMGIDIASAPALQQYRTSAGSPANQSP 475
P+ VP+S P + P +G ++P + T + + P
Sbjct: 466 PIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEP 514
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,265,074
Number of Sequences: 37866
Number of extensions: 2305905
Number of successful extensions: 72756
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1339
Number of HSP's successfully gapped in prelim test: 1748
Number of HSP's that attempted gapping in prelim test: 16960
Number of HSP's gapped (non-prelim): 18321
length of query: 650
length of database: 18,247,518
effective HSP length: 109
effective length of query: 541
effective length of database: 14,120,124
effective search space: 7638987084
effective search space used: 7638987084
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.