BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14602439 Williams Beuren syndrome chromosome region 14 isoform delta [Homo sapiens] (831 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14602439 Williams Beuren syndrome chromosome region 14 isofor... 1715 0.0 gi|14602435 Williams Beuren syndrome chromosome region 14 isofor... 1710 0.0 gi|14602437 Williams Beuren syndrome chromosome region 14 isofor... 1703 0.0 gi|14602433 Williams Beuren syndrome chromosome region 14 isofor... 1698 0.0 gi|111955326 MLX interacting protein [Homo sapiens] 525 e-149 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 105 2e-22 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 102 2e-21 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 101 2e-21 gi|160707881 formin 2 [Homo sapiens] 96 2e-19 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 96 2e-19 gi|47132519 Ras association and pleckstrin homology domains 1 is... 95 3e-19 gi|163965366 nascent polypeptide-associated complex alpha subuni... 92 2e-18 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 91 3e-18 gi|116284392 mucin 2 precursor [Homo sapiens] 89 1e-17 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 86 1e-16 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 85 3e-16 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 84 5e-16 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 83 9e-16 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 82 3e-15 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 82 3e-15 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 82 3e-15 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 82 3e-15 gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 80 6e-15 gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 80 8e-15 gi|11386183 WAS protein family, member 2 [Homo sapiens] 80 1e-14 gi|7706501 WW domain binding protein 11 [Homo sapiens] 79 1e-14 gi|150170670 piccolo isoform 2 [Homo sapiens] 79 2e-14 gi|150378539 piccolo isoform 1 [Homo sapiens] 79 2e-14 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 79 2e-14 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 78 4e-14 >gi|14602439 Williams Beuren syndrome chromosome region 14 isoform delta [Homo sapiens] Length = 831 Score = 1715 bits (4441), Expect = 0.0 Identities = 831/831 (100%), Positives = 831/831 (100%) Query: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD Sbjct: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60 Query: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI Sbjct: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120 Query: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE Sbjct: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180 Query: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR Sbjct: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240 Query: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS Sbjct: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300 Query: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN Sbjct: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360 Query: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP Sbjct: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420 Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS Sbjct: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA Sbjct: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540 Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER Sbjct: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600 Query: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRRITHISAEQKRR 660 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRRITHISAEQKRR Sbjct: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRRITHISAEQKRR 660 Query: 661 FNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVP 720 FNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVP Sbjct: 661 FNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVP 720 Query: 721 ITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAW 780 ITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAW Sbjct: 721 ITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAW 780 Query: 781 LDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 831 LDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL Sbjct: 781 LDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 831 >gi|14602435 Williams Beuren syndrome chromosome region 14 isoform beta [Homo sapiens] Length = 833 Score = 1710 bits (4428), Expect = 0.0 Identities = 831/833 (99%), Positives = 831/833 (99%), Gaps = 2/833 (0%) Query: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD Sbjct: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60 Query: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI Sbjct: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120 Query: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE Sbjct: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180 Query: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR Sbjct: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240 Query: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS Sbjct: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300 Query: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN Sbjct: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360 Query: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP Sbjct: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420 Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS Sbjct: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA Sbjct: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540 Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER Sbjct: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600 Query: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNK--NRRITHISAEQK 658 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNK NRRITHISAEQK Sbjct: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQK 660 Query: 659 RRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATG 718 RRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATG Sbjct: 661 RRFNIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATG 720 Query: 719 VPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSL 778 VPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSL Sbjct: 721 VPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSL 780 Query: 779 AWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 831 AWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL Sbjct: 781 AWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 833 >gi|14602437 Williams Beuren syndrome chromosome region 14 isoform gamma [Homo sapiens] Length = 850 Score = 1703 bits (4411), Expect = 0.0 Identities = 831/850 (97%), Positives = 831/850 (97%), Gaps = 19/850 (2%) Query: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD Sbjct: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60 Query: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI Sbjct: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120 Query: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE Sbjct: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180 Query: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR Sbjct: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240 Query: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS Sbjct: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300 Query: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN Sbjct: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360 Query: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP Sbjct: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420 Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS Sbjct: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA Sbjct: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540 Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER Sbjct: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600 Query: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRRITHISAEQKRR 660 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRRITHISAEQKRR Sbjct: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRRITHISAEQKRR 660 Query: 661 FNIKLGFDTLHGLVSTLSAQPSLK-------------------ERAGLQEEAQQLRDEIE 701 FNIKLGFDTLHGLVSTLSAQPSLK ERAGLQEEAQQLRDEIE Sbjct: 661 FNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAGLQEEAQQLRDEIE 720 Query: 702 ELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESF 761 ELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESF Sbjct: 721 ELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESF 780 Query: 762 NGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRA 821 NGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRA Sbjct: 781 NGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQATRA 840 Query: 822 VTEGTLGKPL 831 VTEGTLGKPL Sbjct: 841 VTEGTLGKPL 850 >gi|14602433 Williams Beuren syndrome chromosome region 14 isoform alpha [Homo sapiens] Length = 852 Score = 1698 bits (4398), Expect = 0.0 Identities = 831/852 (97%), Positives = 831/852 (97%), Gaps = 21/852 (2%) Query: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD Sbjct: 1 MAGALAGLAAGLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLLRSQVIHSGHFMVSSPHSD 60 Query: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI Sbjct: 61 SLPRRRDQEGSVGPSDFGPRSIDPTLTRLFECLSLAYSGKLVSPKWKNFKGLKLLCRDKI 120 Query: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE Sbjct: 121 RLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGPEADAHRKPEAVVLEGNYWKRRIEVVMRE 180 Query: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR Sbjct: 181 YHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGR 240 Query: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS Sbjct: 241 QLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDIS 300 Query: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN Sbjct: 301 DFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARN 360 Query: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP Sbjct: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP 420 Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS Sbjct: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA Sbjct: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540 Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER Sbjct: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600 Query: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNK--NRRITHISAEQK 658 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNK NRRITHISAEQK Sbjct: 601 LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQK 660 Query: 659 RRFNIKLGFDTLHGLVSTLSAQPSLK-------------------ERAGLQEEAQQLRDE 699 RRFNIKLGFDTLHGLVSTLSAQPSLK ERAGLQEEAQQLRDE Sbjct: 661 RRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYILMLQQERAGLQEEAQQLRDE 720 Query: 700 IEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFE 759 IEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFE Sbjct: 721 IEELNAAINLCQQQLPATGVPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFE 780 Query: 760 SFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQAT 819 SFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQAT Sbjct: 781 SFNGMVSTASVHTLRQTSLAWLDQYCSLPALRPTVLNSLRQLGTSTSILTDPGRIPEQAT 840 Query: 820 RAVTEGTLGKPL 831 RAVTEGTLGKPL Sbjct: 841 RAVTEGTLGKPL 852 >gi|111955326 MLX interacting protein [Homo sapiens] Length = 919 Score = 525 bits (1352), Expect = e-149 Identities = 373/940 (39%), Positives = 491/940 (52%), Gaps = 159/940 (16%) Query: 11 GLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLL------------------------RSQV 46 G QV + D D+D+++PS ++G R Q+ Sbjct: 17 GRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPPPRAGPGREEPPRRQQI 76 Query: 47 IHSGHFMVSSPHSDSLPRR----------RDQEGSVGPSDFGPRSIDPTLTRLFECLSLA 96 IHSGHFMVSSPH + P++ Q S G + SID +LT+LFEC++LA Sbjct: 77 IHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLA 136 Query: 97 YSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGP-EAD 155 YSGKLVSPKWKNFKGLKL RDKIRLNNAIWRAWY+QY+++RK+PVC FVTPL G + D Sbjct: 137 YSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVD 196 Query: 156 AHRKPEAVVLEGNYWKRRIEVVMREYHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPE 215 HR+PEA+ EG YWK RIE+V+REYHKWR Y+KKRL++ +++DL + Q + Sbjct: 197 EHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQ-HKDEDLSSLVQDDDML---- 251 Query: 216 QWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISDTLF-TMTQSGPSPLQLPPEDA 274 W K PV + EE+P LLD + +S+ SDTLF T++ P P E A Sbjct: 252 YWHKHGDGWKTPVPM---EEDP----LLDTDMLMSEFSDTLFSTLSSHQPVAWPNPREIA 304 Query: 275 YVGNADMIQPDLTPLQPSLDDFMD----ISDFFTNSRL---PQPPMPSNFPEP-PSFSPV 326 ++GNADMIQP L PLQP+LD FMD D F++SR P ++ P P P+ P Sbjct: 305 HLGNADMIQPGLIPLQPNLD-FMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPA 363 Query: 327 VDSLFSSGTLGPEV--------PPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLL 378 +S+ + L P V PP + ++ H+ C + ++ F+ Sbjct: 364 QESILPTTAL-PTVSLPDSLIAPPTAPSLAHMD-------EQGC----EHTSRTEDPFIQ 411 Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPP-----FPPMAPPTALLQEE--PLF 431 P D P PP VP P L P +P L P P PP P + PP L P F Sbjct: 412 PTDFGPSEPPLSVPQPFL---PVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468 Query: 432 SPRFPFPTVPPAPGVSPLPAPAAF----PPTPQSV----------PSPAPTPFPIELLPL 477 F V AP V A A P T S P+P+ P + L P+ Sbjct: 469 HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528 Query: 478 GYSEPAFGPCFSMPR------GKP---------PAPSPRGQKASPPTLAPATAS--PPTT 520 P F P+ G+P P P P +APA S P Sbjct: 529 T-RPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAV 587 Query: 521 AGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580 ++ P + + A+ Q+ + + + R+PG VPEF + L P Sbjct: 588 IMTSGPLKREGMLASTVSQS-NVVIAPAAIARAPG-----VPEFHSSILVTDLGHGTSSP 641 Query: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSER-RLSGDLSSMPGPGTLSVRVSPPQPILSR 639 P + L PS P + P GS + ++G P G S S P S Sbjct: 642 PAPVSRLFPSTAQ-DPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSP--SP 698 Query: 640 GRPDSN-------------KNRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPS---- 682 P +N KNR++ HISAEQKRRFNIK+ FD L+ L+S S S Sbjct: 699 QSPQNNCSGKSDPKNVAALKNRQMKHISAEQKRRFNIKMCFDMLNSLISNNSKLTSHAIT 758 Query: 683 -----------LKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFDQMRD 731 +ER +QEEA++LR+EIEELNA I CQQ LPATGVP+T ++FD M+D Sbjct: 759 LQKTVEYITKLQQERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKD 818 Query: 732 MFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAWLDQYCSLPALR 791 MFD+YV+TRTL NWKFW+FSI+I+PLFESF GMVST+S+ L +T+L+WLDQ+CSLP LR Sbjct: 819 MFDEYVKTRTLQNWKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILR 878 Query: 792 PTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 831 P VL++LRQL TSTSILTDP ++PEQA++AVT +GK L Sbjct: 879 PMVLSTLRQLSTSTSILTDPAQLPEQASKAVTR--IGKRL 916 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 105 bits (262), Expect = 2e-22 Identities = 120/405 (29%), Positives = 151/405 (37%), Gaps = 50/405 (12%) Query: 252 ISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSL--DDFMDISDFFTNSRLP 309 I L T + P LQ PP A + P L L PSL S T L Sbjct: 508 IMPPLETQSSLAPPSLQTPP-------ASLTTPPLENL-PSLAPPPLQTASAPLTTPHLE 559 Query: 310 QPPMPSNFP--EPPS--FSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCP-G 364 PP P+ P PPS +P ++ S T P+ PPA ++ LQ S P Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP-------LQGLPSPPLS 612 Query: 365 PLDSSAFLSSDFL-LPEDPKPRLPPPPVPPPL--LHYPPPAKVPGLE------PCPPPPF 415 PL + + L LP P P PP PPL L P P L P PPP Sbjct: 613 PLATPPPQAPPXLALPPLQAP--PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670 Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELL 475 PP+ P + P+ P PP+ PL P + P +P PS P P Sbjct: 671 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA---- 726 Query: 476 PLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAA 535 P P +P P +P PP + P A+PP + P + A Sbjct: 727 ----PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782 Query: 536 KPEQALEPPLVSSTLLRSPGSPQE---TVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592 KP P L + L P P P P LP +P TP PP P LA P Sbjct: 783 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP--PPQAPPVLA--AP 838 Query: 593 LL-VPKAERLSPPAPSGSERRLSGDLSSMPGPG-TLSVRVSPPQP 635 LL VP + SP + G +S+ GP TL++ PP P Sbjct: 839 LLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 883 Score = 92.0 bits (227), Expect = 2e-18 Identities = 109/356 (30%), Positives = 149/356 (41%), Gaps = 47/356 (13%) Query: 267 LQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFP--EPPSFS 324 LQ PP + + +P + F+ +S T + L P P++ P PP + Sbjct: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA 459 Query: 325 PVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKP 384 P+ SL +S L + PA S ++ LQA +S A LSS + P + + Sbjct: 460 PL--SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH-SPQAPLSSLIMPPLETQS 516 Query: 385 RLPPPPV--PPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPP 442 L PP + PP L PP +P L P PP+ +A PL +P PP Sbjct: 517 SLAPPSLQTPPASLTTPPLENLPSLAP------PPLQTASA-----PLTTPHLE---TPP 562 Query: 443 APGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMP--RGKPPAP-S 499 P PL AP P+P + P P TP I P P P + P +G P P S Sbjct: 563 CPAPCPLQAP----PSPLTTP-PPETPSSIATPP-----PQAPPALASPPLQGLPSPPLS 612 Query: 500 PRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQE 559 P PP P A PP A + P L A P P ++ LL++P SP Sbjct: 613 PLA--TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ-APNALAVHLLQAPFSPPP 669 Query: 560 TVPEFPCTFLPP-----TPAPTPPRPPPGPATLAPSRPLLVPKAERLSPP-APSGS 609 + P F PP +P+ TPP P P+ AP PL VP + SPP +PS + Sbjct: 670 S-PPVQAPFSPPASPPVSPSATPPSQAP-PSLAAP--PLQVPPSPPASPPMSPSAT 721 Score = 72.8 bits (177), Expect = 1e-12 Identities = 102/380 (26%), Positives = 127/380 (33%), Gaps = 71/380 (18%) Query: 252 ISDTLFTMTQSGPS----PLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSR 307 +S + +Q+ PS PLQ+PP P P+ PS Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSP----------PASPPMSPSATPPPQAPPPLAAPP 734 Query: 308 LPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLD 367 L PP P P P SP S T P VPP +A LQ S P L Sbjct: 735 LQVPPSP---PASPPMSP-------SATPPPRVPPLLAAPP-------LQVPPSPPASLP 777 Query: 368 SSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYP-PPAKVPGLEPCPPPPFPPMAP-PTALL 425 S P P+ PP PPL P PPA PG P P PM+P T Sbjct: 778 MSPLAK--------PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829 Query: 426 QEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFG 485 Q P+ + P VPP+P SP PPTP S + + L P Sbjct: 830 QAPPVLAA--PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP--------- 878 Query: 486 PCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPL 545 G PP PS + S P A ++A S L + + A PP Sbjct: 879 -------GPPPPPS---RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 928 Query: 546 VSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPA 605 + P + P P F AP P P GP + + + + PA Sbjct: 929 DAELAACHPAA-WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 987 Query: 606 PSGSERRLSGDLSSMPGPGT 625 P G L P PGT Sbjct: 988 P--------GALDPGPSPGT 999 Score = 69.7 bits (169), Expect = 1e-11 Identities = 105/442 (23%), Positives = 134/442 (30%), Gaps = 117/442 (26%) Query: 304 TNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCP 363 T LP+P PS P PP+ P +S E PA+ G + A S Sbjct: 185 TEVGLPRPA-PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243 Query: 364 G---PLDSSAFLSSDF-------LLPEDPKPR----LPPPPVPPPLLHYPP--------P 401 PL S A P PKP+ L PP V PP P P Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303 Query: 402 AKVPG-----LEPCPPP------------PFPPMAPPTALLQEEPLFSPRFPFPTVPPAP 444 P P PPP P PP+A P L P P PPA Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363 Query: 445 GVSPLPAPAAFPP--------------TPQSVPSPA--PTPFPIELLPLGYSEPAFGPCF 488 S P PP P S+ SP+ P P+ L L + P Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423 Query: 489 -------------------------SMPRGKPPAPSPRGQKASPP---TLAPATA--SPP 518 S P PP +P ASPP +L+PA + S P Sbjct: 424 QATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP 483 Query: 519 TTA------------GSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEF-- 564 T P + ++ + + +L PP + + P E +P Sbjct: 484 LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAP 543 Query: 565 ------------PCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERR 612 P PP PAP P + PP P T P ++ P P Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPE-----TPSSIATPPPQAPPAL 598 Query: 613 LSGDLSSMPGPGTLSVRVSPPQ 634 S L +P P + PPQ Sbjct: 599 ASPPLQGLPSPPLSPLATPPPQ 620 Score = 44.7 bits (104), Expect = 4e-04 Identities = 67/247 (27%), Positives = 86/247 (34%), Gaps = 22/247 (8%) Query: 377 LLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPP----------PPFPPMAPPTALLQ 426 L P P PPPPV P L A G +P P P A PT Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT---- 80 Query: 427 EEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGP 486 S R P + PPA G AP A +P V SP PLG Sbjct: 81 RSAGTSSRNP-ASRPPASGRGE-RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138 Query: 487 CFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLV 546 ++ RGK + K S + + T G+ +P + + AA E L P Sbjct: 139 EETVARGK----ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194 Query: 547 SSTLLRSPGSPQETVPE-FPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPA 605 S+ P+++V + P+PA RP G P+ L A LS PA Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPA-ARRRPSAGGGLQRPASRSLSSSATPLSSPA 253 Query: 606 PSGSERR 612 SG R Sbjct: 254 RSGPSAR 260 Score = 43.1 bits (100), Expect = 0.001 Identities = 56/234 (23%), Positives = 74/234 (31%), Gaps = 20/234 (8%) Query: 417 PMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLP 476 P A LL P SPR P P P A V P + P E P Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP-ESAP 75 Query: 477 LGYSEPAFGPCFSMPRGKPPAPSPRGQKASP-------PTLAPATASPPTTAG------- 522 + G P +PPA S RG++A P P +P AS T G Sbjct: 76 RAGPTRSAGTSSRNPASRPPA-SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134 Query: 523 ---SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTP-P 578 + T A AL T +PG+P + P P P Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194 Query: 579 RPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSP 632 P P T P + + + P+P+ R +G P +LS +P Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 102 bits (253), Expect = 2e-21 Identities = 109/359 (30%), Positives = 146/359 (40%), Gaps = 45/359 (12%) Query: 309 PQPPMPSNFP--EPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPL 366 P P P PP +P ++ LGP +SS + S + LQ++ P L Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKD--AAPALGPL---SSSPLATPSPSAALQSQ--APPTL 321 Query: 367 DSSAFLSSDFLLPEDPKPRLPPPPVPPPLLH-YPPPAKVPGLEPCPPPPFPPMAPPTALL 425 ++ SS P P PP P PP L P P P + P + + L Sbjct: 322 PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 381 Query: 426 QEEPLFSPRFPFPTVPPAPGVSPL---PAPAAFPP-TPQSVPSP-APTPFPIELLPLGYS 480 PL P P PPA + PL P+P A PP +P + PSP AP + LL +S Sbjct: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441 Query: 481 EPAFGPC---FSMPRGKPPAPSPRGQKASPPTLA--------PATASPPTTAGSNNPCLT 529 P P FS P P +PS +PP+LA ASPP + + P Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 501 Query: 530 QLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTF-----------LPPTPAPTPP 578 AA P Q +PP + L +P P + +P P +F LP +P TP Sbjct: 502 PPPLAAPPLQLAKPPPQAPPALATP--PLQALPSPPASFPGQAPFSPSASLPMSPLATP- 558 Query: 579 RPPPGPATLAPSRPLL-VPKAERLSPPAPSGSERRLSGDLSSMPGPG-TLSVRVSPPQP 635 PP P LA PLL VP + SP + G +S+ GP TL++ PP P Sbjct: 559 -PPQAPPVLA--APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614 Score = 92.0 bits (227), Expect = 2e-18 Identities = 123/435 (28%), Positives = 159/435 (36%), Gaps = 44/435 (10%) Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSF 323 P PL P A + P TP + + T+S LP PP+ PP Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396 Query: 324 SPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAF-------LSSDF 376 P +L P PPAS ++ L+ S QA N+ L + F + + F Sbjct: 397 PP---ALALPPLQAPPSPPASPPLSPLATPSP-QAPNALAVHLLQAPFSPPPSPPVQAPF 452 Query: 377 LLPEDP--KPRLPPPPVPPPLLHYPP------PAKVPGLEP--CPPPPFPP--MAPPTAL 424 P P P PP PP L PP P P + P PPP PP APP L Sbjct: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512 Query: 425 LQEEPLFSPRFPFPTV-----PPA--PGVSPLPAPAAFPPTPQSVPSP-APTPFPIELLP 476 + P P P + PPA PG +P A+ P +P + P P AP LL Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572 Query: 477 LGYSEPAFGPCFSMPRGKPPAPSPRGQKASPP-TLAPATASPPTTAGSNNPCLTQLLTAA 535 + S PA P PR +PP P P + P TLA A PP + S + L+ A Sbjct: 573 VPPSPPA-SPTLQAPR-RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630 Query: 536 KPEQALEPPLVSSTLLRSP--GSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPL 593 A P P G+ P+ P P PP AP PL Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA-FRGAPGAPL 689 Query: 594 LVPKAERLSPPAPSG--SERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRRIT 651 P A P + G + G S+ P PG L P P S G+ + + Sbjct: 690 PWPPA--TGPGSADGLCTIYETEGPESATPAPGALD---PGPSPGTSGGKAAAGAGAGAS 744 Query: 652 HISAEQKRRFNIKLG 666 S +Q R + LG Sbjct: 745 SRSPKQARLGELPLG 759 Score = 44.7 bits (104), Expect = 4e-04 Identities = 67/247 (27%), Positives = 86/247 (34%), Gaps = 22/247 (8%) Query: 377 LLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPP----------PPFPPMAPPTALLQ 426 L P P PPPPV P L A G +P P P A PT Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT---- 80 Query: 427 EEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGP 486 S R P + PPA G AP A +P V SP PLG Sbjct: 81 RSAGTSSRNP-ASRPPASGRGE-RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138 Query: 487 CFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLV 546 ++ RGK + K S + + T G+ +P + + AA E L P Sbjct: 139 EETVARGK----ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194 Query: 547 SSTLLRSPGSPQETVPE-FPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPA 605 S+ P+++V + P+PA RP G P+ L A LS PA Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPA-ARRRPSAGGGLQRPASRSLSSSATPLSSPA 253 Query: 606 PSGSERR 612 SG R Sbjct: 254 RSGPSAR 260 Score = 44.3 bits (103), Expect = 5e-04 Identities = 63/223 (28%), Positives = 75/223 (33%), Gaps = 53/223 (23%) Query: 448 PLPAPAAFPPTPQSVP----SPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP-------- 495 P PAP+A P P P S A E P P+ G P + Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249 Query: 496 PAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEP---------PLV 546 +P+ G A APA S P G L A +P Q P PL Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKG---------LQALRPPQVTPPRKDAAPALGPLS 300 Query: 547 SSTL--------LRSPGSPQETVPEFP------CTFLPPTP-APTPPRPPPGPATLAPSR 591 SS L L+S P T+P P C P P AP P PP TL PS Sbjct: 301 SSPLATPSPSAALQSQAPP--TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL-PSP 357 Query: 592 PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634 P P S +P+ L S +P P + PPQ Sbjct: 358 PATPPSQATTSLGSPT-----LQATHSFLPSPPLSPLATPPPQ 395 Score = 43.1 bits (100), Expect = 0.001 Identities = 56/234 (23%), Positives = 74/234 (31%), Gaps = 20/234 (8%) Query: 417 PMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLP 476 P A LL P SPR P P P A V P + P E P Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP-ESAP 75 Query: 477 LGYSEPAFGPCFSMPRGKPPAPSPRGQKASP-------PTLAPATASPPTTAG------- 522 + G P +PPA S RG++A P P +P AS T G Sbjct: 76 RAGPTRSAGTSSRNPASRPPA-SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134 Query: 523 ---SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTP-P 578 + T A AL T +PG+P + P P P Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194 Query: 579 RPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSP 632 P P T P + + + P+P+ R +G P +LS +P Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 101 bits (252), Expect = 2e-21 Identities = 113/357 (31%), Positives = 144/357 (40%), Gaps = 55/357 (15%) Query: 325 PVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLP-EDPK 383 P SL SS T P PA S + G R A S P P A P +D Sbjct: 228 PASRSLSSSAT--PLSSPARSGPS-ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 284 Query: 384 PRLPP---PPVPPPLLHYPP-PAKVPGLEPCPPPPFPPMAPPT------------ALLQE 427 P L P P+ P PP P+ P L+ P PP P + T + L Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344 Query: 428 EPLFSPRFPFPTVPPAPGVSPL---PAPAAFPP-TPQSVPSP-APTPFPIELLPLGYSEP 482 PL P P PPA + PL P+P A PP +P + PSP AP + LL +S P Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404 Query: 483 AFGPC---FSMPRGKPPAPSPRGQKASPPTLA--------PATASPPTTAGSNNPCLTQL 531 P FS P P +PS +PP+LA ASPP + + P Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464 Query: 532 LTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTF-----------LPPTPAPTPPRP 580 AA P Q +PP + L +P P + +P P +F LP +P TP P Sbjct: 465 PLAAPPLQLAKPPPQAPPALATP--PLQALPSPPASFPGQAPFSPSASLPMSPLATP--P 520 Query: 581 PPGPATLAPSRPLL-VPKAERLSPPAPSGSERRLSGDLSSMPGPG-TLSVRVSPPQP 635 P P LA PLL VP + SP + G +S+ GP TL++ PP P Sbjct: 521 PQAPPVLA--APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575 Score = 92.0 bits (227), Expect = 2e-18 Identities = 123/435 (28%), Positives = 159/435 (36%), Gaps = 44/435 (10%) Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSF 323 PSP P A + P TP + + T+S LP PP+ PP Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357 Query: 324 SPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAF-------LSSDF 376 P +L P PPAS ++ L+ S QA N+ L + F + + F Sbjct: 358 PP---ALALPPLQAPPSPPASPPLSPLATPSP-QAPNALAVHLLQAPFSPPPSPPVQAPF 413 Query: 377 LLPEDP--KPRLPPPPVPPPLLHYPP------PAKVPGLEP--CPPPPFPP--MAPPTAL 424 P P P PP PP L PP P P + P PPP PP APP L Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473 Query: 425 LQEEPLFSPRFPFPTV-----PPA--PGVSPLPAPAAFPPTPQSVPSP-APTPFPIELLP 476 + P P P + PPA PG +P A+ P +P + P P AP LL Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533 Query: 477 LGYSEPAFGPCFSMPRGKPPAPSPRGQKASPP-TLAPATASPPTTAGSNNPCLTQLLTAA 535 + S PA P PR +PP P P + P TLA A PP + S + L+ A Sbjct: 534 VPPSPPA-SPTLQAPR-RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591 Query: 536 KPEQALEPPLVSSTLLRSP--GSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPL 593 A P P G+ P+ P P PP AP PL Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLA-FRGAPGAPL 650 Query: 594 LVPKAERLSPPAPSG--SERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRRIT 651 P A P + G + G S+ P PG L P P S G+ + + Sbjct: 651 PWPPA--TGPGSADGLCTIYETEGPESATPAPGALD---PGPSPGTSGGKAAAGAGAGAS 705 Query: 652 HISAEQKRRFNIKLG 666 S +Q R + LG Sbjct: 706 SRSPKQARLGELPLG 720 Score = 44.3 bits (103), Expect = 5e-04 Identities = 85/326 (26%), Positives = 101/326 (30%), Gaps = 77/326 (23%) Query: 377 LLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPP----------PPFPPMAPPTALLQ 426 L P P PPPPV P L A G +P P P A PT Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR--T 82 Query: 427 EEPLFSPRF----PFPTVPPAPGVSPLPAPAAFPPTP-----------QSVPSPAPTPFP 471 P S R P P P SP A P P ++V T P Sbjct: 83 SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 142 Query: 472 -IELLPLGYSEPAFGPCFSMP------------------------RGKPPAPSPRGQKAS 506 L G GP P R +PP PR +S Sbjct: 143 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202 Query: 507 P---PTLAPATAS---PPTTAGSNNPCLTQLLTAAKP--EQALEPPLVSSTLLRSPGSPQ 558 T P+ A+ P G P L ++A P A P T R+P P Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT-PRAPAHPS 261 Query: 559 ETVPEFPCTFLPPTPAPTPPRPPPGPATLAP--SRPLLVPKAERLSPPAPSGSERRLSGD 616 + P+ P P TPPR PA L P S PL P +PP+PS Sbjct: 262 QPKPKGLQALRP--PQVTPPRKDAAPA-LGPLSSSPLATPSPS--APPSPSAPP-----S 311 Query: 617 LSSMPGPGTLSVRVSPPQPILSRGRP 642 L ++P P P Q S G P Sbjct: 312 LQTLPSPPA----TPPSQATTSLGSP 333 Score = 39.7 bits (91), Expect = 0.012 Identities = 56/234 (23%), Positives = 74/234 (31%), Gaps = 29/234 (12%) Query: 417 PMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLP 476 P A LL P SPR P P P A V P + P Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP----- 71 Query: 477 LGYSEPAFGPCFSMPRGKPPAPSPRGQKASP-------PTLAPATASPPTTAG------- 522 S P GP + +PPA S RG++A P P +P AS T G Sbjct: 72 --ESAPRAGPTRT---SRPPA-SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 125 Query: 523 ---SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTP-P 578 + T A AL T +PG+P + P P P Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 185 Query: 579 RPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSP 632 P P T P + + + P+P+ R +G P +LS +P Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 239 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 95.5 bits (236), Expect = 2e-19 Identities = 124/420 (29%), Positives = 149/420 (35%), Gaps = 66/420 (15%) Query: 268 QLPPEDAYVGNADMIQPDLTPLQPSLDDFM-----DISDFFTNSRLPQPPMPSNFPEPPS 322 Q PP + + +A QP P +F +S F NS N P PP Sbjct: 809 QPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNS--------CNIPSPPP 860 Query: 323 FSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDP 382 P +S S LG VPP + ++ + P PL + L P P Sbjct: 861 L-PCTESSSSMPGLGM-VPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPP----PPPP 914 Query: 383 KPRL---PPPPVP-------PPL--LHYPPPAKVPGLEPCPPPPFP----PMAPP---TA 423 P PPPP+P PPL PPP +PG PPPP P P+ PP Sbjct: 915 LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG 974 Query: 424 LLQEEPLFSPRFPFPTVPPAPGVS---PLPAPAAFPPTPQSVPS---PAPTPFPIELLPL 477 + PL P P PP PG P P P A P P +P P P P P +P Sbjct: 975 IPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1032 Query: 478 GYSEPAFG--PCFSMP-RGKPPAPSPRGQKASPPTLAPATA--SPPTTAGSNNPCLTQLL 532 P G P +P G PP P G PP P PP G+ P L Sbjct: 1033 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1092 Query: 533 TAAKPEQALEPPLVSSTLLRSPGSPQETV---PEFPCTFLPPTPAPTP----PRPPPGPA 585 A P PPL + P P + P P +PP P P P P PPP P Sbjct: 1093 GAGIPP---PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPR 1148 Query: 586 TLAPSRPLLVPKAERLSPPAPSGS---ERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRP 642 P P L PP P L G + P P V + PP P+ G P Sbjct: 1149 VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-VGIPPPPPLPGVGIPPPPPLPGAGIP 1207 Score = 91.7 bits (226), Expect = 3e-18 Identities = 110/355 (30%), Positives = 124/355 (34%), Gaps = 70/355 (19%) Query: 308 LPQPPMP-SNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPL 366 LP PP+P + P PP G P PP A L L P P Sbjct: 932 LPLPPLPGAGIPPPPPLP---------GAAIPPPPPLPGAGIPLP--PPLPGAGIPPPPP 980 Query: 367 DSSAFLSSDFLLPE---DPKPRLP----PPPVPPPLLHYPPPAKVPGLEPCPPPPFP--- 416 A + LP P P LP PPP P P PPP +PG PPPP P Sbjct: 981 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040 Query: 417 ----PMAPPTALLQEEPLFSPRFPFPTVPPAPGVS---PLPAPAAFPPTPQSVPS---PA 466 P P + PL P P PP PG P P P A P P +P P Sbjct: 1041 IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1098 Query: 467 PTPFPIELLPLGYSEPAFG--PCFSMP-RGKPPAPSPRGQKASPPTLAPATA--SPPTTA 521 P P P +P P G P +P G PP P G PP P PP Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158 Query: 522 GSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPE---FPCTFLPPTP----- 573 G+ P L A P PPL + P P +P P +PP P Sbjct: 1159 GAGIPPPPPLPGAGIPPP---PPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM 1215 Query: 574 ----APTPPRPPPG-----PATLAPSRPLLVPKAER-----------LSPPAPSG 608 AP PP PPPG P L S P L+P+ L PP PSG Sbjct: 1216 GIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSG 1270 Score = 60.8 bits (146), Expect = 5e-09 Identities = 59/196 (30%), Positives = 68/196 (34%), Gaps = 46/196 (23%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDS 368 P PP+P PP P V G +PP P PL Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPP--------------------PPPLPG 1170 Query: 369 SAFLSSDFLLPEDPKPRLP----PPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTAL 424 + P P LP PPP P P + PPP +PG PPPP P M P A Sbjct: 1171 AGI---------PPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPA- 1220 Query: 425 LQEEPLFSPRFPFPTVPPAPGVSPLP-APAAFPP-TPQSVPSPAPTPFPIELLPLGYSEP 482 P P P PP G+ P P P + PP PQ S PTP LP Sbjct: 1221 --------PAPPLP--PPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSG 1270 Query: 483 AFGPCFSMPRGKPPAP 498 FG + +G P Sbjct: 1271 LFGLGMNQDKGSRKQP 1286 Score = 55.5 bits (132), Expect = 2e-07 Identities = 72/263 (27%), Positives = 87/263 (33%), Gaps = 33/263 (12%) Query: 395 LLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLF-SPR---FPFPTVPPAPGVS-PL 449 +L PP +PG PCPP P T E L SPR + P +S P Sbjct: 754 VLTLPPVDGLPGRPPCPPG--AESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811 Query: 450 PAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP-PAPSPRGQKASP- 507 P P+ Q P P P I E + F P P P P + +S Sbjct: 812 PPPSLLWSAGQGQPGSQP-PHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSM 870 Query: 508 PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPG--------SPQE 559 P L PP G P L + A P+ PPL + +L P P Sbjct: 871 PGLGMVPPPPPPLPGMTVPTLP---STAIPQ---PPPLQGTEMLPPPPPPLPGAGIPPPP 924 Query: 560 TVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSS 619 +P LPP P P PPP P P P L L PP P Sbjct: 925 PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA---------GI 975 Query: 620 MPGPGTLSVRVSPPQPILSRGRP 642 P P + PP P+ G P Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIP 998 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 95.5 bits (236), Expect = 2e-19 Identities = 117/399 (29%), Positives = 155/399 (38%), Gaps = 35/399 (8%) Query: 226 VPVLLGDPEEEPGGRQLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPD 285 VP L P P + + + S +S T+ ++ S P+ +P +A + P Sbjct: 1403 VPSSLPGPASSP--MPIPNSSPLASPVSSTV-SVPLSSSLPISVPTTLPAPASAPLTIPI 1459 Query: 286 LTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSG-TLGPEVPPAS 344 PL S T+ P P+ P PPS +P S +S TLG P+ Sbjct: 1460 SAPLTVSASG----PALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSL 1515 Query: 345 SAMTHLSGHSRLQARNSC--PGPLDSSAFLSSDFLLPED----PKPRLPPPPVPPPLLHY 398 S+ + GH L A S PG + A S L+P P P P P L Sbjct: 1516 SS-SQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLA 1574 Query: 399 PPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPT 458 P + L P P AP TA+L P P P P + P+PG +P+ A + P Sbjct: 1575 PASSASQALAT---PLAPMAAPQTAILAPSPA-PPLAPLPVLAPSPGAAPVLASSQ-TPV 1629 Query: 459 PQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPP 518 P PS P P+ P P + P PSP AS TLA A A P Sbjct: 1630 PVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAP 1689 Query: 519 TTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGS-----PQETVPEFPCTFLPPTP 573 T GS +P T L P + P + TL +P S P +T+ P L PT Sbjct: 1690 TLGGS-SPSQTLSLGTGNP----QGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQ 1744 Query: 574 ----APTPPRPPPGPATLAPSRPL-LVPKAERLSPPAPS 607 AP PP P P AP+ L L P + S AP+ Sbjct: 1745 TLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPA 1783 Score = 66.6 bits (161), Expect = 9e-11 Identities = 107/397 (26%), Positives = 141/397 (35%), Gaps = 59/397 (14%) Query: 282 IQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSN---FPEPPSFSPVVDSLFSSGTLGP 338 + P P L ++ T RLP P + + P P P++ + S P Sbjct: 1327 LAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPS---P 1383 Query: 339 EVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFL--SSDFLLPEDPKPRLP-----PPPV 391 EV ++ L+ S L +S PGP S + SS P +P P V Sbjct: 1384 EVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISV 1443 Query: 392 PPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPP-------AP 444 P L P PA P P P + P L P +P P PP +P Sbjct: 1444 PTTL---PAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASP 1500 Query: 445 GVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP---PAPSPR 501 S L A P+ S +P P+ L P P + P P PA + Sbjct: 1501 SASALTLGLATAPSLSSSQTPG---HPLLLAPTSSHVPGLNSTVA-PACSPVLVPASALA 1556 Query: 502 GQKASPPTLAPATASPPTTAGSNNPCL-TQLLTAAKPEQAL-----EPPLVSSTLLR-SP 554 S P APA AS A S + L T L A P+ A+ PPL +L SP Sbjct: 1557 SPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSP 1616 Query: 555 G------SPQETVPEFPCTFLP--------PTPAPTPPRPPPGPATLAPS---RPLLVPK 597 G S Q VP + P P PAPTP P T+ P+ PL P Sbjct: 1617 GAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPA 1676 Query: 598 AERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634 + + AP+ L+ L TLS+ PQ Sbjct: 1677 STQTLALAPA-----LAPTLGGSSPSQTLSLGTGNPQ 1708 Score = 63.9 bits (154), Expect = 6e-10 Identities = 85/299 (28%), Positives = 111/299 (37%), Gaps = 43/299 (14%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDS 368 P P+P P P + +PV L SS T P + P+S+ T L+ S + P P Sbjct: 1605 PLAPLPVLAPSPGA-APV---LASSQTPVPVMAPSSTPGTSLASASPV------PAPTPV 1654 Query: 369 SAFLSSDFLLPEDPKPRLPPP---------PVPPPLLHYPPPAKVPGLEPCPPP-PFPP- 417 A S+ +LP LP P P P L P++ L P PFP Sbjct: 1655 LAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQ 1714 Query: 418 ---MAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIEL 474 + P ++L+ P P + P +S PAP P +P P+PA T + L Sbjct: 1715 TLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVG-PAPAHT---LTL 1770 Query: 475 LPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTA 534 P S P PAP P A+ TLA A AS + A + + A Sbjct: 1771 APASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGA 1830 Query: 535 AK---------PEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGP 584 A P EP + TL P SP T F P P PP PP P Sbjct: 1831 APLPVTMVSRLPVSKDEPDTL--TLRSGPPSPPSTATSFG----GPRPRRQPPPPPRSP 1883 Score = 60.8 bits (146), Expect = 5e-09 Identities = 94/353 (26%), Positives = 132/353 (37%), Gaps = 78/353 (22%) Query: 356 LQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPP---PPVPPPLLHYPPPAKV-------P 405 +QA PGP S SS P P VPP +++ K+ Sbjct: 1260 IQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRD 1319 Query: 406 GLEPCPP---PPFPPMAPPTALLQEEPLFSP-RFPFPTVPPAPGVSPLPAPAAFPPTPQS 461 GL P PP P PP + A+L P +P R P PT+ A +P+P P P + Sbjct: 1320 GLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTAR--APMPTPTLVRPLLKL 1377 Query: 462 VPSPAP--TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS--- 516 V SP+P + PL S P P S+P PA SP S P +P +++ Sbjct: 1378 VHSPSPEVSASAPGAAPLTISSPLHVPS-SLPG---PASSPMPIPNSSPLASPVSSTVSV 1433 Query: 517 ----------PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSS-------TLLRSPGSPQ- 558 P T + LT ++A A P L++S + +PG P Sbjct: 1434 PLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSL 1493 Query: 559 ----------------ETVPEFPCTFLPPTP---APTPPRPPPGPATLAPS-RPLLVPKA 598 T P + P P APT P +T+AP+ P+LVP + Sbjct: 1494 APSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPAS 1553 Query: 599 ERLSP------PAP---------SGSERRLSGDLSSMPGPGTLSVRVSPPQPI 636 SP PAP S + + L+ L+ M P T + SP P+ Sbjct: 1554 ALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPL 1606 Score = 55.8 bits (133), Expect = 2e-07 Identities = 85/316 (26%), Positives = 113/316 (35%), Gaps = 59/316 (18%) Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVP 441 P P L P P P+ P + + P PP P PP +L PL P V Sbjct: 1028 PGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLL-PPLQPNSGSLPQVL 1086 Query: 442 PAP-----GVSPLPAPA-AFPPTPQSVP--SPAPTPFPIELL-----PLGYSEP------ 482 P+P G S P P + PTP + SPAP P LL P GY+ P Sbjct: 1087 PSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATT 1146 Query: 483 -----AFGPCFSMPRGKPPAPS------------PRGQKASPPTLAPATASPPTTAGSNN 525 A ++P PAP P G+ S LA P AG + Sbjct: 1147 TSTTTATATTTAVP-APTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSK 1205 Query: 526 PCLTQL------LTAAKPEQAL--EP-PLVSSTL-LRSPGSPQETVPEFPCTFL----PP 571 P Q+ LT A+ Q +P PL + + L S G + + L P Sbjct: 1206 PLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAP 1265 Query: 572 TPAPTPPR--PPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVR 629 TP PTP P P+T L +P A PP + + + P G Sbjct: 1266 TPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDG----- 1320 Query: 630 VSPPQPILSRGRPDSN 645 ++P P+ RP S+ Sbjct: 1321 LTPVPPLAPAPRPPSS 1336 Score = 55.1 bits (131), Expect = 3e-07 Identities = 95/368 (25%), Positives = 128/368 (34%), Gaps = 86/368 (23%) Query: 384 PRLPPPPVPPPLLHYPPPAKVPGLEPCP-PPPFPPMAP-PTALLQEEPLFSPRFPFPTVP 441 PR P P P P PA +P L P P P P AP P +L P P+ P Sbjct: 2437 PRPAPRPRPTPA---SAPAAIPALVPVPVSAPVPISAPNPITIL-------PVHILPSPP 2486 Query: 442 PAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPR 501 P + P +PA PP P P PA TP P + + S P S+P P Sbjct: 2487 PPSQIPPCSSPACTPP-PACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPL 2545 Query: 502 GQKASPPTLAPATASP-----PTTAGSNN------------PCLTQLLTAAKPEQALEPP 544 G + A A ASP + A S P ++L ++ +L P Sbjct: 2546 GLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPS 2605 Query: 545 LVSSTL----------LRSPGSPQET--------------VPEFPCTFLPPTPAPTPPRP 580 S TL +P S + T V E LPP+ A P Sbjct: 2606 APSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQ 2665 Query: 581 PPGPA-------------TLAPSRPLLVPKAERLSP------------PAPSGSERRLSG 615 P A T +P +P + AE +P P+P+ RR + Sbjct: 2666 EPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTS 2725 Query: 616 DLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRRITHISAEQ--KRRFNIKLGFDTLHGL 673 + G GT PP P + R P R +T + ++ +RR + TL Sbjct: 2726 ADVEIRGQGT-GRPGQPPGPKVLRKLP----GRLVTVVEEKELVRRRRQQRGAASTLVPG 2780 Query: 674 VSTLSAQP 681 VS SA P Sbjct: 2781 VSETSASP 2788 Score = 53.1 bits (126), Expect = 1e-06 Identities = 68/275 (24%), Positives = 96/275 (34%), Gaps = 46/275 (16%) Query: 409 PCPPP-PFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAP 467 P PPP P P +LQ P R P + P+P PP P+ P P Sbjct: 981 PDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRP--PPGPELSAQPTP 1038 Query: 468 TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPC 527 P P ++LP A SP G P L PA+ P Sbjct: 1039 GPVP-QVLPASLMVSA---------------SPAG-----PPLIPASRPPGPV------- 1070 Query: 528 LTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATL 587 LL +P P ++ S L G+ + P PP P P PPPG ++L Sbjct: 1071 ---LLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSL 1127 Query: 588 APSRPLLVPKAERLSP-PAPSGSERRLSGDLSSMPGPGTLSVRV---------SPPQPIL 637 +PL VP P A + S + +++P P R+ P ++ Sbjct: 1128 L--KPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVV 1185 Query: 638 SRGRPDSNKNRRITHISAEQKRRFNIKLGFDTLHG 672 S G+ S R + + + F I+ TL G Sbjct: 1186 SIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTG 1220 Score = 51.6 bits (122), Expect = 3e-06 Identities = 106/411 (25%), Positives = 137/411 (33%), Gaps = 95/411 (23%) Query: 307 RLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPL 366 R+P+P P P P S + +L P A + +T L H P P Sbjct: 2435 RVPRPA-PRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHI-------LPSPP 2486 Query: 367 DSSAFLSSDFLLPEDPKPRLPPPPV-PPPLLHYPPPAKVPGLEPCPPPPF-PPMAPPTAL 424 S +P P PPP PP H PPPA+ + P P PP P +A Sbjct: 2487 PPSQ-------IPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISAS 2539 Query: 425 LQEEPL-FSPRFPFPTVPPAPGVSPLPAPAAFPPTPQS--VPSPAPTPFPIELLPLGYSE 481 + PL P A S A A T VP P +E+LP+ Sbjct: 2540 VTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKN 2599 Query: 482 PAFGPCFSMPRGKPPAPS-PRGQKASPPTLAPATASPPTTAGSNNP-CLTQ-----LLTA 534 + P S P A S P GQ+ P A T G P C+++ L + Sbjct: 2600 LSLTP--SAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPS 2657 Query: 535 AKPEQALEPPLVSS----------TLLRSPGSPQETVPE---FPCTFLPPTPAPTPPRP- 580 A ++ L+ PL + T SP PQE V P T T +P P P Sbjct: 2658 AASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPA 2717 Query: 581 -----------------------PPGPATLA--PSRPL---------------------L 594 PPGP L P R + L Sbjct: 2718 RPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTL 2777 Query: 595 VPKAERLSPPAPSGSERRLSGDLSSMP--GP----GTLSVRVSPPQPILSR 639 VP S S S R +SG SS P GP + S+ P QP ++R Sbjct: 2778 VPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIAR 2828 Score = 50.4 bits (119), Expect = 7e-06 Identities = 67/268 (25%), Positives = 97/268 (36%), Gaps = 63/268 (23%) Query: 384 PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPA 443 PR P PVP PPP +P P P P + P + ++ P P P Sbjct: 1015 PRAPLGPVPVR----PPPGPELSAQPTPGP-VPQVLPASLMVSASPAGPPLIP------- 1062 Query: 444 PGVSPLPAPAAFPP-TPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRG 502 S P P PP P S P P P+ +L +PP P+ Sbjct: 1063 --ASRPPGPVLLPPLQPNSGSLPQVLPSPLGVL--------------SGTSRPPTPT-LS 1105 Query: 503 QKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVP 562 K +PP AP SP GS++ L + LT P PP ++T + + T Sbjct: 1106 LKPTPP--APVRLSPAPPPGSSS--LLKPLTV--PPGYTFPPAAATTTSTTTATATTTA- 1158 Query: 563 EFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLS----------PPAPSGSER- 611 PAPT P P L+P +P E +S P A +G + Sbjct: 1159 ---------VPAPT---PAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKP 1206 Query: 612 ---RLSGDLSSMPGPGTLSVRVSPPQPI 636 ++ G+ ++ G + V P+P+ Sbjct: 1207 LTFQIQGNKLTLTGAQVRQLAVGQPRPL 1234 Score = 40.4 bits (93), Expect = 0.007 Identities = 55/218 (25%), Positives = 75/218 (34%), Gaps = 61/218 (27%) Query: 441 PPAPGVSPLPAPAAFPPT--------PQSVPSPAPTPF----PIELLPLGYSEPAFG--- 485 P +P V + P + PP S+P+P PF IEL G P G Sbjct: 2788 PGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGA 2847 Query: 486 ------PCFSMPRGKPP----APSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAA 535 P RG+PP +P+ G+ AP++ T G++ + L A Sbjct: 2848 LLAITPPAVKRRRGRPPKKNRSPADAGRGVDE---APSSTLKGKTNGADPVPGPETLIVA 2904 Query: 536 KPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLV 595 P LEP L+ P P P P+P P PLL Sbjct: 2905 DP--VLEPQLI------------------------PGPQPLGPQPVHRP------NPLLS 2932 Query: 596 PKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPP 633 P +R P + + G +SS G G R PP Sbjct: 2933 PVEKRRRGRPPKARDLPIPGTISS-AGDGNSESRTQPP 2969 Score = 32.0 bits (71), Expect = 2.4 Identities = 86/342 (25%), Positives = 105/342 (30%), Gaps = 86/342 (25%) Query: 403 KVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPL-------PAPAAF 455 K G +P P P +A P Q P P P P P P +SP+ P A Sbjct: 2888 KTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARD 2947 Query: 456 PPTPQSVPS-----------PAPTPFPIELLP---------LGYSEPAFGPCFSMP---R 492 P P ++ S P P P P+ LP + + S P R Sbjct: 2948 LPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKR 3007 Query: 493 GKPP--APSPR---------------------------GQKASPPTLAPATASPPTT--- 520 G+PP PSPR GQ S + + S P T Sbjct: 3008 GRPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLA 3067 Query: 521 --------------AGSNNPCLTQ----LLTAAKPEQALEPPLVSST-LLRSPG-SPQET 560 GS + Q L + L PP+VS T LRS P Sbjct: 3068 RLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSLTPKLRSTRLRPGSL 3127 Query: 561 VPEFPCTFLPPTPAPTPPRPPPGPA---TLAPSRPLLVPKAERLSPPAPSGSERRLSGDL 617 VP LP A P PG A L P PL + S SG E G Sbjct: 3128 VPPLETEKLPRKRAGAPVGGSPGLAKRGRLQPPSPLGPEGSVEESEAEASGEEEEGDGTP 3187 Query: 618 SSMPGPGTL-SVRVSPPQPILSRGRPDSNKNRRITHISAEQK 658 PGP L Q IL P S ++H + K Sbjct: 3188 RRRPGPRRLVGTTNQGDQRILRSSAPPSLAGPAVSHRGRKAK 3229 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 94.7 bits (234), Expect = 3e-19 Identities = 122/417 (29%), Positives = 151/417 (36%), Gaps = 82/417 (19%) Query: 272 EDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSR----LPQPPMPSNFPEPPSFSPVV 327 E++ + + T L P L I +T S+ LP PP P P PP P Sbjct: 588 EESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP 647 Query: 328 ----DSLFSSGTLGPEVPPASSA--MTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPED 381 S S+G+ P S+ + + S HS + P + S + + P Sbjct: 648 PLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNG 707 Query: 382 PKPRLPPPPVPP---------------PLLHY----PPPAKV----------PGLEPCPP 412 P PPPP PP P L PPP K+ P P PP Sbjct: 708 VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP 767 Query: 413 P---PFPPMAPPTALLQEEPLFSPRFPFPTV------PPAPGVSPLPAPAAFPPT--PQS 461 P P PP APP L+ S + P V P P V P AFP + P S Sbjct: 768 PIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827 Query: 462 VPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKAS---PPTLAPATASPP 518 P+P P P P LP S A P P P PS Q AS PP PA S P Sbjct: 828 PPTP-PVPVPPPTLPKQQSFCAKPP----PSPLSPVPSVVKQIASQFPPPPTPPAMESQP 882 Query: 519 TTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578 N Q A K + +P SS + SP P PE F PP P+P P Sbjct: 883 LKPVPAN-VAPQSPPAVKAKPKWQP---SSIPVPSPDFPPPP-PESSLVFPPPPPSPVPA 937 Query: 579 RPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 PPP P T +P+ P SGS + + SS G + PP P Sbjct: 938 PPPPPPPTASPT-------------PDKSGSPGKKTSKTSSPGG------KKPPPTP 975 Score = 84.7 bits (208), Expect = 3e-16 Identities = 81/293 (27%), Positives = 105/293 (35%), Gaps = 52/293 (17%) Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTA--------------LLQE 427 P P LPPPP PPP PPP P PPPP P + P+A LQ Sbjct: 624 PSPPLPPPPPPPP----PPPPPPPP----PPPPLPSQSAPSAGSAAPMFVKYSTITRLQN 675 Query: 428 EPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPC 487 S P PP + PP P P P P P + +PA PC Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA--PC 733 Query: 488 F-SMPRGKPPAP-------------SPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLT 533 S+P+ P P +P PP AP P P T T Sbjct: 734 APSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKT 793 Query: 534 AAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPL 593 A PP + P P + P FP +++PP+P PTPP P P P P + Sbjct: 794 VAPVVTQAAPPTPT-----PPVPPAKKQPAFPASYIPPSP-PTPPVPVPPPT--LPKQQS 845 Query: 594 LVPKAERLSPPAPSGSERRLSGDLSSM--PGPGTLSVRVSPPQPILSRGRPDS 644 K PP+P + ++S P P ++ P +P+ + P S Sbjct: 846 FCAK----PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQS 894 Score = 63.2 bits (152), Expect = 1e-09 Identities = 101/399 (25%), Positives = 138/399 (34%), Gaps = 95/399 (23%) Query: 266 PLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSP 325 P+ +PP + +P +PL P I+ S+ P PP P P P Sbjct: 832 PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA-----SQFPPPPTPPAMESQP-LKP 885 Query: 326 VVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPR 385 V + P+ PPA A S +P P P Sbjct: 886 V------PANVAPQSPPAVKAKPKWQPSS-----------------------IPV-PSPD 915 Query: 386 LPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPG 445 PPPP L+ PPP P P PPPP PPTA + SP G Sbjct: 916 FPPPPPESSLVFPPPP---PSPVPAPPPP----PPPTASPTPDKSGSPGKKTSKTSSPGG 968 Query: 446 VSPLPAPAAFPPTPQ---SVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRG 502 P PPTPQ S+ S + P P S + + PPA S Sbjct: 969 KKP-------PPTPQRNSSIKSSSGAEHPEPKRPSVDS--------LVSKFTPPAESGSP 1013 Query: 503 QKAS-PPTLAPATASPPTTAGSNNP-CLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQET 560 K + PP AP +G N P L Q +AK P++S G +++ Sbjct: 1014 SKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAK------APVLS-------GRGKDS 1060 Query: 561 VPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSM 620 V EF P+P PPP P T P P+ +P SG+ ++ Sbjct: 1061 VVEF------PSPPSDSDFPPPPPETELPLPPIEIPAVF-------SGNTSPKVAVVNPQ 1107 Query: 621 PGP-GTLSVRVSPPQPILSRGRPDSNKNRRITHISAEQK 658 P +SV+ +PP RP N + R+T ++ Sbjct: 1108 PQQWSKMSVKKAPPPT-----RPKRNDSTRLTQAEISEQ 1141 Score = 35.8 bits (81), Expect = 0.17 Identities = 63/253 (24%), Positives = 78/253 (30%), Gaps = 58/253 (22%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLF-SSGTLGPEVPPASSAMTHLSGHSR----LQARNSCP 363 P+P PS F+P +S S TL P P +LSG + Q S Sbjct: 990 PEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAK 1049 Query: 364 GPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPP---PAKVPG-------------- 406 P+ S S P P PPP P L PP PA G Sbjct: 1050 APVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQ 1109 Query: 407 ------LEPCPPPPFPPMAPPTALLQEEPLFSPRFP--FPTVPPAPGVSPLPAPAAFPPT 458 ++ PPP P T L Q E P P VP +P S P Sbjct: 1110 QWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADL 1169 Query: 459 PQSVPSPAPT------------------------PFPIELLP----LGYSEPAFGPCFSM 490 +++ + T P P ELL GY ++ Sbjct: 1170 NRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATL 1229 Query: 491 PRGKPPAPSPRGQ 503 RG PPAP R Q Sbjct: 1230 RRGPPPAPPKRDQ 1242 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 92.0 bits (227), Expect = 2e-18 Identities = 116/472 (24%), Positives = 161/472 (34%), Gaps = 83/472 (17%) Query: 233 PEEEPGGRQLLDLNCFLSDISDTLFTMTQSGPSPLQLPPE-------DAYVGNADMIQPD 285 P E+ G L+ ++D+ + S + PP D +GN + Sbjct: 771 PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGN---LSSP 827 Query: 286 LTPLQPSLD-----DFMDISDFFTNSRLPQPPMPSNFPEPPSFSP--------------- 325 ++P++ S F D + P PP P P P + +P Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT 887 Query: 326 --VVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPE--D 381 VV+ F P + A++ S + P + +S P Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP 947 Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP-PTALLQEEPLFSPRFPFPT- 439 P P+ P P PP A P + P P P AP P A P P P P Sbjct: 948 PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007 Query: 440 --VPPA---------PGVSPLPA-----PAAFPPTPQSVPSPAPTPFPIELLPLG-YSEP 482 PPA P +P P PAA PP+P+ P+ P P P P Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067 Query: 483 AFGPCFSM--------------PRGKPPAPSPRGQK----ASPPTLAPATASPPTTAGSN 524 GP P+G P PSP+G A+PP+ A+PP Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127 Query: 525 NPCLTQLLTAAKPEQALEPPL-VSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPG 583 P T + K A PP +T +P SP+ + P P TPA TPP P G Sbjct: 1128 TPAATP--PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185 Query: 584 PATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 AT +P P A +PP+P G G + P + +PP P Sbjct: 1186 LATPSPKGAPTTPAA---TPPSPKG------GLATPSPKGAPTTPAATPPSP 1228 Score = 82.0 bits (201), Expect = 2e-15 Identities = 97/370 (26%), Positives = 138/370 (37%), Gaps = 56/370 (15%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDS 368 P P P P PP+ +P S + TL P P+S G + ++ P + Sbjct: 1324 PGTPPPKGAPTPPAVTP--PSPKGTPTL-PATTPSSKG-----GPTTPSSKEGPTPPAAT 1375 Query: 369 SAFLSSDFLLPEDPK--PRLPPP---PVPPPLLHYPP---PAKVPGLEPCPPPPFPPMAP 420 + + P PK P +P P P P ++ P PA E P + P Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435 Query: 421 PTAL---LQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSP-------APTPF 470 P L++ P S P P + G LPA PP+P+ P+P +P Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT--PPSPKEPPAPKQVATSSSPKKA 1493 Query: 471 PIELLPLGYSE-PAFGPCFSMPRGKPPAPSPRGQ----------KASPPTLAPATASPPT 519 P P+G PA P S P+ P PS R K +P TLAP A P Sbjct: 1494 PATPAPMGAPTLPAVIP--SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551 Query: 520 TAGSNNPCLTQLLTAAKP-------EQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPT 572 +P T + K ++A PP V+ + + SP+E + T P Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611 Query: 573 PAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSP 632 APTPP P P+ P PK SPP S + S P +++ ++ Sbjct: 1612 EAPTPPAVTPPSPEKGPATP--APKGTPTSPPVTPSSLK------DSPTSPASVTCKMGA 1663 Query: 633 PQPILSRGRP 642 P S+G P Sbjct: 1664 TVPQASKGLP 1673 Score = 81.3 bits (199), Expect = 3e-15 Identities = 86/337 (25%), Positives = 116/337 (34%), Gaps = 68/337 (20%) Query: 309 PQPPMPSNFPEPPSFSPVVDS--LFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPL 366 P P P P PP+ +P L + G PA++ + G + + + P Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153 Query: 367 DSSAFLSSDFLLPEDPKPRL--PPPPVPPPLLHYPPPAKVPGLEPCPP------PPFPPM 418 + P PK L PPP P PP+ GL P P P Sbjct: 1154 AT----------PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203 Query: 419 APPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLG 478 +P L P +P P T P G P+P P TP + P Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP--------------- 1248 Query: 479 YSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPE 538 P GP P+G P P+ A+PP+L A+PP G+ NP + Sbjct: 1249 -PSPKGGPATPPPKGAPTPPA-----ATPPSLKGGLATPP-HKGAPNPAVV--------- 1292 Query: 539 QALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKA 598 +P SP+ P P PA TPP P P T P P Sbjct: 1293 --------------TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKG---APTP 1335 Query: 599 ERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 ++PP+P G+ + SS GP T S + P P Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372 Score = 79.7 bits (195), Expect = 1e-14 Identities = 99/351 (28%), Positives = 122/351 (34%), Gaps = 52/351 (14%) Query: 308 LPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLD 367 +P P P P PP+ +P T P+ P A T S + P Sbjct: 930 IPASPSPKGAPTPPAATPPSPK-GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP 988 Query: 368 SSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPP-PPFPPMAPPTALLQ 426 +A S P P P+ P P P + P P P P P PP A P + Sbjct: 989 PAATPPSPKGGPATPSPKGAPTP---PAVTPPSPKGSPAATPFPKGASTPPAATPPS--- 1042 Query: 427 EEPLFSPRF-PFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFG 485 P SP P P P + LP+P P TP +P P P P P G Sbjct: 1043 --PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP---PAATPP----SPKGG 1093 Query: 486 PCFSMPRGKP--PA---PSPRGQKASPPTL-APAT--ASPPTTAGSNNPCLTQLLTAAKP 537 P P+G P PA PSP+G A+PP AP T A+PP+ G T A Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG---LATPPPKGAPT 1150 Query: 538 EQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAP------------TPPRPPPGP- 584 A PP L P T P PP+P TP PP P Sbjct: 1151 TPAATPPSPKGGLATPPPKGAPTTP----AATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206 Query: 585 ATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 LA P P +PP+P G G + P + +PP P Sbjct: 1207 GGLATPSPKGAPTTPAATPPSPKG------GLATPSPKGAPTTPAATPPSP 1251 Score = 78.6 bits (192), Expect = 2e-14 Identities = 91/356 (25%), Positives = 129/356 (36%), Gaps = 34/356 (9%) Query: 312 PMPSNFPEPPSFSPVVDS--LFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSS 369 P P P P+ +P L + G PA++ + G + + + P + Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271 Query: 370 AFLSSDFLLPED---PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQ 426 L P P P + PP P PP P P PP P +P T Sbjct: 1272 PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP-TPPAATPPSPKGSPGTP--- 1327 Query: 427 EEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGP 486 P +P P T P G LPA + PS P P P PA P Sbjct: 1328 -PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386 Query: 487 CFSMPRGKPPAPSPRGQKASP------PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540 P+ P PSP+G SP P APAT P T G+ P L A + Sbjct: 1387 --PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT--PVTREGAATPSKGDLTPPAVTPVS 1442 Query: 541 LEPPLVSSTLLRSPGSPQE----TVPEF--PCTFLPPTP-----APTPPRPPPGPATL-A 588 L+ +S P +P T+P P PP P + +P + P PA + A Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502 Query: 589 PSRPLLVPKAERLSPPAPSGSERRL--SGDLSSMPGPGTLSVRVSPPQPILSRGRP 642 P+ P ++P + + P PS + + L S P TL+ + + P ++ P Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP 1558 Score = 67.8 bits (164), Expect = 4e-11 Identities = 103/429 (24%), Positives = 144/429 (33%), Gaps = 66/429 (15%) Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSF 323 PSP + PP V + P P P+ + +S P PS+ +P + Sbjct: 1473 PSPKE-PPAPKQVATSS--SPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529 Query: 324 SPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPK 383 + + S + TL P+ AMT S + + P P ++ A SS K Sbjct: 1530 TATLLSKKTPATLAPKEALIPPAMTVPSP----KKTPAIPTPKEAPATPSS--------K 1577 Query: 384 PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAP-PTALLQEEPLFSPRFPFPT-VP 441 PP V P P K + P P P AP P A+ P P P P P Sbjct: 1578 EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637 Query: 442 PAPGVSP---------------------------LPAPAAFPPTPQSVPSPAPTPFPIEL 474 +P V+P LPA + + +PAP PI Sbjct: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697 Query: 475 LPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASP-----PTTAGSNNPCLT 529 P + P P + G K T+APA P TA + + Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757 Query: 530 QLLTAAKPEQALEPPLVSST---LLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP----- 581 A PE PL ++ +L P S + P LP P+P P PP Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFL 1817 Query: 582 ---PGPATLAPSRPLLVPKAER---LSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPP-- 633 PG +PS+PL + L PP P L +MP P + + V P Sbjct: 1818 PSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSA 1877 Query: 634 -QPILSRGR 641 QP+ + Sbjct: 1878 KQPVTKNNK 1886 Score = 55.8 bits (133), Expect = 2e-07 Identities = 87/380 (22%), Positives = 124/380 (32%), Gaps = 91/380 (23%) Query: 288 PLQPSLDDFMDISDFFTNSRLP------QPPMPSNFPEP-------PSFSPVVDSLFSSG 334 PL P+ + ++ N+ P P +P + P P P + VD + + Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758 Query: 335 TLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPP 394 L P T SG S A S G L A S + P+ + PP Sbjct: 759 ALAPVASSPKECPTEDSGAS---ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA 815 Query: 395 LLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAA 454 P + L P P +L + SP PP+P +P P+ A Sbjct: 816 ----GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPS-AV 870 Query: 455 FPPTPQSV---PSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLA 511 P +P+ V P PTP + L P+ P P+P+ A Sbjct: 871 TPLSPKGVTLPPKETPTPSVVNL--------------PFPKEGPATPAPKQ--------A 908 Query: 512 PATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPP 571 PA + +T++ P++A P P SP P PP Sbjct: 909 PALS----------------MTSSSPKKARATPAPKGI----PASPSPKGAPTPPAATPP 948 Query: 572 TPAP----------------TPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSG 615 +P TPP P GPAT +P P A +PP+P G G Sbjct: 949 SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAA---TPPSPKG------G 999 Query: 616 DLSSMPGPGTLSVRVSPPQP 635 + P V+PP P Sbjct: 1000 PATPSPKGAPTPPAVTPPSP 1019 Score = 50.8 bits (120), Expect = 5e-06 Identities = 63/237 (26%), Positives = 85/237 (35%), Gaps = 43/237 (18%) Query: 436 PFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP 495 P PT+PP PAP P + + SP P+P I PL P ++P G Sbjct: 41 PGPTLPPPCS----PAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTA 96 Query: 496 P-----APSPRGQKASPPTLAPATAS-PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSST 549 P P+ G SP LA A+ PT G+ + L A P + Sbjct: 97 PEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPN 156 Query: 550 LLRSPGS------------PQETVPEFPCTFLPPTPAPTPPRP--PPGPATLAPSRP--L 593 LL SP S P P T L P+ P P P P + + P Sbjct: 157 LLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHC 216 Query: 594 LVPKAE---------------RLSPPAPSGSERRLSGDLSSMPGPGTLSVR--VSPP 633 + P A L+ +P + +S L S PG+LS++ VSPP Sbjct: 217 VTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPP 273 Score = 35.4 bits (80), Expect = 0.22 Identities = 46/198 (23%), Positives = 70/198 (35%), Gaps = 13/198 (6%) Query: 405 PGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPS 464 P + P P +P ++ P T P PLP P P SV Sbjct: 465 PPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLV 524 Query: 465 PAPTPFPIELLPLGYSEPAFGPC-FSMPRGKPPAPSPRGQKA--SPPTLAPATASP---- 517 PT ++ +P F P + K P P Q A + P+ ++SP Sbjct: 525 KFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPL 584 Query: 518 PTTAGSNNPCLTQLLTAAKPEQALEPPL---VSSTLLR--SPGSPQETVPEFPCTFLPPT 572 A L + L KP ++ PL S+++++ S P P + + PT Sbjct: 585 SPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPT 644 Query: 573 PAPTPPRPPPGPATLAPS 590 A P PA +AP+ Sbjct: 645 VAAF-PLESADPAGVAPT 661 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 91.3 bits (225), Expect = 3e-18 Identities = 114/395 (28%), Positives = 146/395 (36%), Gaps = 49/395 (12%) Query: 258 TMTQSGPSPLQLPPEDAYVGNADM-IQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSN 316 +M P PLQ E +G A + ++P L + L++ M + S L PP S Sbjct: 403 SMQPKEPGPLQC--EAKPLGKAGVQLEPQL---EAPLNEEMPLLPPPEESPLSPPPEESP 457 Query: 317 FPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDF 376 PP S + PE PAS L L+ P P +S Sbjct: 458 TSPPPEASRLSPP--------PEELPASPLPEALHLSRPLEESPLSPPPEES-------- 501 Query: 377 LLPEDPKPRLPP------PPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPL 430 P P P P P+ PP P PA L P PP P++PP +E PL Sbjct: 502 --PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSP--PPEASPLSPP---FEESPL 554 Query: 431 FSPRFPFPTVPP--APGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCF 488 P PT PP A +SP P + P P+ P +P P L P P P Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPM-SPPPEASRLFPPFEESPLSPP-- 611 Query: 489 SMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSS 548 P P +P P + SPP + PP + + P L+ L PP S Sbjct: 612 --PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEES 669 Query: 549 TLLRSP-GSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLL-VPKAERLSPPAP 606 L P SP PE PP +PT P P PA+ P L+ +P E P P Sbjct: 670 PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729 Query: 607 SGSE---RRLSGDLSSMPGPGTLSVRVSPPQPILS 638 + R LS P LS R P +P LS Sbjct: 730 EEPQLCPRSEGPHLSPRPEEPHLSPR--PEEPHLS 762 Score = 85.9 bits (211), Expect = 1e-16 Identities = 126/465 (27%), Positives = 159/465 (34%), Gaps = 72/465 (15%) Query: 191 RLRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLS 250 RL P E + P + PPPE S + P P P L S Sbjct: 571 RLSPPPEESPMSPPPEESPMSPPPEA------SRLFPPFEESPLSPPPEESPLSPPPEAS 624 Query: 251 DISDTLFTMTQSGP---SPLQLPPEDAYVGNADMIQ-----PDLTPLQPSLDDFMDISDF 302 +S S P SP+ PPE + + ++ P+ +PL P ++ S Sbjct: 625 RLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEE-SPTSPP 683 Query: 303 FTNSRLPQPPMPSNFPEPPSFSPVV----DSLFSSGTLGPEVPPASSAMTHLSGHSRLQA 358 SRL PP S PP SP DSL S +P S + L +L Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMS-------LPLEESPLLPLPEEPQLCP 736 Query: 359 RNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPM 418 R+ P L P +P L P P P H P A+ P L P P P Sbjct: 737 RSEGP------------HLSPRPEEPHLSPRPEEP---HLSPQAEEPHLSPQPEEPCLCA 781 Query: 419 APPTALLQEEPLFSPRFPFPTVPPAPG---VSPLPAPAAFPPTPQSVPSPAPTPFPIELL 475 P EEP SP+ P + P P +SP P P+ P +P P L Sbjct: 782 VP------EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE-PCLSPQPEESHLS 834 Query: 476 PLGYSEPAFGP----CFSMPRGKPPAPSPRGQKA-SPPTLAPATASPPTTAGSNNPCLTQ 530 P EP P P + P SPR +K P PA P P L+ Sbjct: 835 PQS-EEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSP 893 Query: 531 LLTAAKPEQALEPPL--VSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLA 588 LL + EPPL + L SP P+ +PP P P PP P A Sbjct: 894 LLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL----MPPDPLP----PPLSPIITA 945 Query: 589 PSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPP 633 + P L P E P G D S L +SPP Sbjct: 946 AAPPALSPLGELEYPFGAKG-----DSDPESPLAAPILETPISPP 985 Score = 84.0 bits (206), Expect = 5e-16 Identities = 100/345 (28%), Positives = 126/345 (36%), Gaps = 48/345 (13%) Query: 311 PPMPSNFP--EPPSFSPVVDSLFSSG---TLGPEVPPASSAMTHLSGHSRLQARNSCPGP 365 PP P + P EP + G ++ P+ P G + +Q P Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433 Query: 366 LDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTAL- 424 L+ L L P + P PPP P PP + L P PP P P AL Sbjct: 434 LNEEMPL----LPPPEESPLSPPPEESPT----SPPPEASRLSP-PPEELPASPLPEALH 484 Query: 425 ----LQEEPLFSPRFPFPTVPPAPG--VSPLPAPAAFPPTPQSVPSPA---PTPFPIELL 475 L+E PL P P PP SPL PP +S PSPA P P E Sbjct: 485 LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPE-ESPPSPALETPLSPPPEAS 543 Query: 476 PLGYSEPAF--GPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLT 533 PL P F P P P +P P + SPP + PP + + P L Sbjct: 544 PLS---PPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF 600 Query: 534 AAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAP---- 589 E L PP S L P + + L P P +P PPP + ++P Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASR----------LSPPPEDSPMSPPPEESPMSPPPEV 650 Query: 590 SRPLLVPKAERLSPPAPSGSERRLSGDLSSMP-GPGTLSVRVSPP 633 SR +P RLSPP E LS P P + R+SPP Sbjct: 651 SRLSPLPVVSRLSPPP---EESPLSPPPEESPTSPPPEASRLSPP 692 Score = 83.6 bits (205), Expect = 7e-16 Identities = 135/494 (27%), Positives = 179/494 (36%), Gaps = 79/494 (15%) Query: 192 LRKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVP--VLLGDP-EEEPGGRQLLDLNCF 248 L P E P +A PPPE +L +S +P + L P EE P + Sbjct: 449 LSPPPEESPTSPPPEASRLSPPPE----ELPASPLPEALHLSRPLEESPLSPPPEESPLS 504 Query: 249 LSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRL 308 S + +S SP + P + P+ +PL P ++ +S Sbjct: 505 PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE-SPLSPPPEELPT 563 Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDS 368 PP S PP SP+ PP S M+ SRL P + Sbjct: 564 SPPPEASRLSPPPEESPM------------SPPPEESPMSPPPEASRLFP------PFEE 605 Query: 369 SAFLSSDFLLPEDPKP---RLPPPPVPPPLLHYPPPAKVPGLEPCPPP------PFPPMA 419 S P P P RL PPP P+ PPP + P PPP P P ++ Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPPPEDSPM--SPPPEESP---MSPPPEVSRLSPLPVVS 660 Query: 420 PPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTP-------FPI 472 + +E PL P PT PP P P P +P SPA P P+ Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720 Query: 473 E---LLPLGYSEPAF-----GPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSN 524 E LLPL EP GP S PR + P SPR ++ P L+P P + Sbjct: 721 EESPLLPLP-EEPQLCPRSEGPHLS-PRPEEPHLSPRPEE---PHLSPQAEEPHLSPQPE 775 Query: 525 NPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQ------ETVPEFPCTFLPPTPAPTPP 578 PCL + E P +S SPQ VPE PC P + P Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835 Query: 579 R-------PPPGPATLAP--SRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVR 629 + P P + L+P +P L P+ E+ PP G + +L P PG S+ Sbjct: 836 QSEEPCLSPRPEESHLSPELEKPPLSPRPEK--PPEEPG-QCPAPEELPLFPPPGEPSLS 892 Query: 630 VSPPQPILSR-GRP 642 +P LS G P Sbjct: 893 PLLGEPALSEPGEP 906 Score = 82.8 bits (203), Expect = 1e-15 Identities = 122/447 (27%), Positives = 157/447 (35%), Gaps = 86/447 (19%) Query: 195 PSREDDLLAPKQAEGRWPPPEQWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISD 254 P ED ++P E PP + + VV L PEE P LS + Sbjct: 628 PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP-----------LSPPPE 676 Query: 255 TLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMP 314 T S L PPED+ P+ +P P +D + + LP P P Sbjct: 677 ESPTSPPPEASRLSPPPEDSPTSPP----PEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732 Query: 315 SNFP--EPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFL 372 P E P SP + S PE P HLS + + P A Sbjct: 733 QLCPRSEGPHLSPRPEEPHLSPR--PEEP-------HLSPQAEEPHLSPQPEEPCLCAVP 783 Query: 373 SSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQ---EEP 429 L P+ P L P P LH P + P L P P P P + L EEP Sbjct: 784 EEPHLSPQAEGPHLSPQPEE---LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP 840 Query: 430 LFSPR---------------FPFPTVPPA-PGVSPLPAPAA-FPPTPQSVPSP------- 465 SPR P P PP PG P P FPP + SP Sbjct: 841 CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL 900 Query: 466 --------APTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASP 517 +P P + L P G EP+ P P PP SP A+PP L+P Sbjct: 901 SEPGEPPLSPLPEELPLSPSG--EPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGE-- 956 Query: 518 PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTP 577 + AK + E PL ++ +L +P SP PE CT P P P Sbjct: 957 -----------LEYPFGAKGDSDPESPL-AAPILETPISPP---PEANCT--DPEPVPPM 999 Query: 578 PRPPPGPATLAPSRPLLV-PKAERLSP 603 PP + + P+ P+L+ P + SP Sbjct: 1000 ILPPSPGSPVGPASPILMEPLPPQCSP 1026 Score = 63.5 bits (153), Expect = 8e-10 Identities = 94/359 (26%), Positives = 127/359 (35%), Gaps = 50/359 (13%) Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSF 323 P P + P E + + P +PSL + P P+P P PS Sbjct: 862 PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG 921 Query: 324 SPVVD-SLFSSGTLGPEVPP--ASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFL-LP 379 P + L L P + P ++A LS L+ G D + L++ L P Sbjct: 922 EPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETP 981 Query: 380 EDPKPRL---PPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQE--EPLFSPR 434 P P P PVPP +L PP P P+ P + +L E P SP Sbjct: 982 ISPPPEANCTDPEPVPPMIL--------------PPSPGSPVGPASPILMEPLPPQCSPL 1027 Query: 435 FPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPI-------ELLPLGYSEPAFGPC 487 VP SP P+ + P P SVPSP + EL + + + C Sbjct: 1028 LQHSLVPQN---SP-PSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPEC 1083 Query: 488 FSM-PRGKPPAPSPRGQKASP-PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPL 545 ++ P P PSP G + P P+ APA P ++PE P Sbjct: 1084 PALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGS 1143 Query: 546 VSSTLLRSPG--SPQETVPEFPCTFLP----------PTPAPTPPRPP--PGPATLAPS 590 ++S L SP P+E P P P P PR P P P TL S Sbjct: 1144 LASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKS 1202 Score = 55.8 bits (133), Expect = 2e-07 Identities = 92/323 (28%), Positives = 111/323 (34%), Gaps = 62/323 (19%) Query: 334 GTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPP 393 G LG PP ++A T G + P L +SA FL P P +P P P Sbjct: 2111 GALGS--PPPAAAPTIFIGSP------TTPAGLSTSA---DGFLKP--PAGSVPGPDSPG 2157 Query: 394 PL-LHYPP--PAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPA--PGVSP 448 L L PP PA+VP +P P P+ P FPT PP P SP Sbjct: 2158 ELFLKLPPQVPAQVPSQDPFGLAPAYPLEPR---------------FPTAPPTYPPYPSP 2202 Query: 449 LPAPAAFPPTPQSVPSPAPTPFPIELLPLG--YSEPAFGPCFSMPR-------GKPPAPS 499 APA P S A P P G +P+ F PR P +P Sbjct: 2203 TGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262 Query: 500 PRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQE 559 G KAS P L SPP S + L K E P L SP Sbjct: 2263 VGGGKASEPLL-----SPPPFGESR-----KALEVKKEELGASSPSYGPPNLGFVDSPSS 2312 Query: 560 TVP------EFPCTFLPP-TPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERR 612 + P F P TP + P L P P P A+ L+P PS + Sbjct: 2313 GTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP---PPAQALAPSPPSHPDIF 2369 Query: 613 LSGDLSSMPGPGTLSVRVSPPQP 635 G + L+ R PP P Sbjct: 2370 RPGSYTDPYAQPPLTPRPQPPPP 2392 Score = 52.4 bits (124), Expect = 2e-06 Identities = 80/340 (23%), Positives = 109/340 (32%), Gaps = 82/340 (24%) Query: 332 SSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDP---KPRL-- 386 S G LG +S++ HL + D ++ + L P+ P +P Sbjct: 4115 SHGQLGSGSSSEASSVPHLLAQPSVSLG-------DQPGSMTQNLLGPQQPMLERPMQNN 4167 Query: 387 --PPPPVPPPLLHYPPPAKVPGLEP-------------CPPPPFPPMAPPT-----ALLQ 426 P PP P P+L G+ P P ++P ALL Sbjct: 4168 TGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLM 4227 Query: 427 EEPLFSPRFPFPTVP-PAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFG 485 + L + T P PG P PQ P P P++ L G Sbjct: 4228 QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAG------- 4280 Query: 486 PCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPL 545 P+G P P+P G ++ P L P +PP Sbjct: 4281 ---PRPQGPPRLPAPPGALSTGPVLGPVHPTPP--------------------------- 4310 Query: 546 VSSTLLRSPGSPQETVPEFPCTF-LPPTPAPTPPR-PPPGPATLAPSRPLLVPKAERLSP 603 P SPQE P+ P P + PT + PP P T P P L P R+SP Sbjct: 4311 --------PSSPQE--PKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSP 4360 Query: 604 PAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPD 643 A ++ S L P L+ P Q L G D Sbjct: 4361 AAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLD 4400 Score = 47.4 bits (111), Expect = 6e-05 Identities = 97/369 (26%), Positives = 123/369 (33%), Gaps = 57/369 (15%) Query: 270 PPEDAYVGNADMIQPDL--TPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSPVV 327 P ++G ++ PD+ PL P S PP + P PPS + Sbjct: 2310 PSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI- 2368 Query: 328 DSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLP 387 F G+ P A +T R P P A LP DP R+P Sbjct: 2369 ---FRPGSYTD--PYAQPPLT---------PRPQPPPPESCCALPPRS--LPSDPFSRVP 2412 Query: 388 PPPVPPPLLHYP-PPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGV 446 P P P + CP P P P + R PF + P Sbjct: 2413 ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP-- 2470 Query: 447 SPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPP--APSPRGQK 504 P P AF + S FP LP G PA +P G+PP SP G Sbjct: 2471 RPQPPEVAFKAGSLAHTSLGAGGFP-AALPAG---PAGELHAKVPSGQPPNFVRSP-GTG 2525 Query: 505 ASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPL-VSSTLLRSP--GSPQETV 561 A T +P + P G + L P+ L PP ++S P G PQ T Sbjct: 2526 AFVGTPSPMRFTFPQAVGEPS------LKPPVPQPGLPPPHGINSHFGPGPTLGKPQST- 2578 Query: 562 PEFPCTFLPPTPAPTPPRPPPGPAT--------LAPSRPLLVPKAERLSPPAPSGSERRL 613 + T P P GP++ L+P RP V L PPAP GS L Sbjct: 2579 -----NYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSV-----LPPPAPDGSLPYL 2628 Query: 614 SGDLSSMPG 622 S S G Sbjct: 2629 SHGASQRSG 2637 Score = 44.7 bits (104), Expect = 4e-04 Identities = 56/209 (26%), Positives = 66/209 (31%), Gaps = 57/209 (27%) Query: 440 VPPAPGVSPLPAPAAFP------PT---------------------------------PQ 460 +PP PG P PAA P PT P Sbjct: 2106 IPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPP 2165 Query: 461 SVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTT 520 VP+ P+ P L P EP F + P PP PSP G A PP L ++ Sbjct: 2166 QVPAQVPSQDPFGLAPAYPLEPRFP---TAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQ 2222 Query: 521 AGS--NNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578 G P T + P+ L+P R P VPE P P Sbjct: 2223 PGEFHTTPPGTPRHQPSTPDPFLKP--------RCPSLDNLAVPESPGVGGGKASEPLLS 2274 Query: 579 RPPPGPATLAPSRPLLVPKAERLSPPAPS 607 PP G SR L K E L +PS Sbjct: 2275 PPPFG-----ESRKALEVKKEELGASSPS 2298 Score = 40.8 bits (94), Expect = 0.005 Identities = 87/378 (23%), Positives = 114/378 (30%), Gaps = 82/378 (21%) Query: 390 PVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPL 449 P+ P P + GL P PPP +AP P P P P P Sbjct: 2330 PLTPRASQVEPQSPGLGLRPQEPPPAQALAP-------SPPSHPDIFRPGSYTDPYAQPP 2382 Query: 450 PAPAAFPPTPQSVPSPAPTPFPIE------------------LLPLGYSEPAFGPCFSMP 491 P PP P+S + P P + L P S AF P P Sbjct: 2383 LTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTP 2442 Query: 492 RGKPPAP------SPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTA--------AKP 537 R + P P P+ + P P PP A L A A P Sbjct: 2443 RFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGP 2502 Query: 538 EQALEPPLVSS---TLLRSPGSPQETVPEFPCTFL-----------PPTPAPTPPRPPPG 583 L + S +RSPG+ P F PP P P P P Sbjct: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI 2562 Query: 584 PATLAPSRPLLVPKAERL-----------SPPAPSGSERRLSGDLSSMPGPGTLSVRVSP 632 + P L P++ SP PS S LS + P L P Sbjct: 2563 NSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL----PP 2618 Query: 633 PQPILSRGRPDSNKNRRITHISAEQKRRFNIKLGFDTLHGLVSTLSA-------QPSLKE 685 P P S ++R S +KR D G+ S+L+ P + Sbjct: 2619 PAPDGSLPYLSHGASQRSGITSPVEKRE-------DPGTGMGSSLATAELPGTQDPGMSG 2671 Query: 686 RAGLQEEAQQLRDEIEEL 703 + + E Q+ R + EL Sbjct: 2672 LSQTELEKQRQRQRLREL 2689 Score = 38.1 bits (87), Expect = 0.034 Identities = 24/66 (36%), Positives = 26/66 (39%), Gaps = 6/66 (9%) Query: 392 PPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPA 451 PPP PPP+ P P P P P L EPL P P P + S P Sbjct: 4909 PPPEEPSPPPS------PLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPK 4962 Query: 452 PAAFPP 457 P A PP Sbjct: 4963 PRARPP 4968 Score = 37.0 bits (84), Expect = 0.075 Identities = 36/124 (29%), Positives = 44/124 (35%), Gaps = 31/124 (25%) Query: 390 PVPPPLLHYPPPAKVPGLEP---CPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGV 446 P P P + V L+ PPP P PP SP P P PP + Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPP----------SPLAPSPASPPTEPL 4933 Query: 447 SPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKAS 506 LP P P P+P LPL S + P PR +PP G+ + Sbjct: 4934 VELPTEPLAEP-------PVPSP-----LPLASSPESARP---KPRARPP---EEGEDSR 4975 Query: 507 PPTL 510 PP L Sbjct: 4976 PPRL 4979 Score = 35.4 bits (80), Expect = 0.22 Identities = 103/466 (22%), Positives = 152/466 (32%), Gaps = 111/466 (23%) Query: 300 SDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQAR 359 S T + L PP P + PP+ P V +G V P+ H + AR Sbjct: 4608 SQLLTKNNLSNPPTPPS-SLPPTPPPSVQQKMVNG-----VTPSEELGEHPKDAA--SAR 4659 Query: 360 NSCPGPLDSSAFLSSDFL--LPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP-----P 412 +S D+S S D L LP P + + P + VP P Sbjct: 4660 DSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEA 4719 Query: 413 PPFPPMAPPTALLQEEPLFSPRFPF---PTVPPAPGVSP-----LPAPAAFPPTP----- 459 P FP + QE+ SP P ++P P P L P P T Sbjct: 4720 PRFPHLGSGR-WEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGK 4778 Query: 460 ------------------------------QSVPSPAPTPFPIELLPLGYSEPAFGPCFS 489 +P+ FP G +EP G Sbjct: 4779 GSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAG-TEPKKGEAEG 4837 Query: 490 MPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPL---- 545 P GK + P L A P + + LL P A EPP Sbjct: 4838 -PGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESP--APEPPTQHSY 4894 Query: 546 ---VSSTLLRSPGSPQETVPEFPCTFLPPTP-APTPPRPPPGPATLAPSRPLLVPKAERL 601 VS+ +R +P PE P PP+P AP+P PP P P+ PL Sbjct: 4895 TYNVSNLDVRQLSAPP---PEEPSP--PPSPLAPSPASPPTEPLVELPTEPL-------A 4942 Query: 602 SPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRRITHISAEQKRRF 661 PP PS L+S P R PP+ + ++ R+ + +R Sbjct: 4943 EPPVPSPL------PLASSPESARPKPRARPPE------EGEDSRPPRLKKWKGVRWKRL 4990 Query: 662 NIKLGFDTLHGLVSTLSAQPSLKERAGLQEEAQQLRDEIEELNAAI 707 + L ++++ +G QE+ +++ + +E+L A+ Sbjct: 4991 RLLL----------------TIQKGSGRQEDEREVAEFMEQLGTAL 5020 Score = 34.3 bits (77), Expect = 0.49 Identities = 47/178 (26%), Positives = 67/178 (37%), Gaps = 38/178 (21%) Query: 499 SPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQ 558 SP+ Q+ L P + P S+ L L EQ P VSS P + Q Sbjct: 3986 SPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQ 4045 Query: 559 ------ETVPEFPCTFLPPTPAPT----------PPRPPPGPATLAPSRPLLVPKAER-- 600 T PE T P P+ P+P P P++L PL +P ++ Sbjct: 4046 GGPLAIGTTPESMAT-EPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQ 4104 Query: 601 --LSPPAPSGSERRL----SGDLSSMP------------GPGTLSVR-VSPPQPILSR 639 L A GS +L S + SS+P PG+++ + P QP+L R Sbjct: 4105 VSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLER 4162 Score = 30.4 bits (67), Expect = 7.1 Identities = 55/213 (25%), Positives = 76/213 (35%), Gaps = 36/213 (16%) Query: 332 SSGTLGPE----VPPASSAMTHLSG----HSRLQARNSCPG--PLDSSAFLSSDFLLPED 381 ++G +GP P+S A LS + Q ++S G P S + P D Sbjct: 2710 AAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSD 2769 Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEP-CPPPPFPPMAP-------------PTALLQE 427 + PPPP P + V G + P+P P TA Sbjct: 2770 DRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSM 2829 Query: 428 EPLFSPRFPFPTVPPAPGVSPLPAPAA-----FPPTPQSVPSPAPTPFPIELLPLGYS-E 481 S RFP T P G L +P A P + VP PA P + + L ++ + Sbjct: 2830 RFAMSARFP-STPGPELGRQALGSPLAGISTRLPGPGEPVPGPAG---PAQFIELRHNVQ 2885 Query: 482 PAFGPCFSMPRGKPPAPSPRGQKAS--PPTLAP 512 GP + G+ P PR S P LAP Sbjct: 2886 KGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAP 2918 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 89.4 bits (220), Expect = 1e-17 Identities = 101/399 (25%), Positives = 145/399 (36%), Gaps = 57/399 (14%) Query: 260 TQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPE 319 T S P+ PP + + P TP P+ + P PP+ + Sbjct: 1398 TPSPPTTTPSPPPTS----TTTLPPTTTPSPPTTTTTTP-----PPTTTPSPPITTTTTP 1448 Query: 320 PPSFSPVVDSLFSSGTLGPEV----PPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSD 375 PP+ +P S+ T P PP ++ + S + P P + + ++ Sbjct: 1449 PPTTTP--SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1506 Query: 376 FLLPEDPKPRLPP-----PPV-----PPPLLHYPPPAKVPGLEPCP----PPPFPPMAPP 421 + P LPP PP PPP PP P P PP P PP Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566 Query: 422 TALLQEEPLFSPRFPFPTVPPAPGV---SPLPAPAAFPP-TPQSVPSPAPTPFPIELLPL 477 T P +P P T P P + +P P PP T + P P TP P P+ Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1626 Query: 478 GYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKP 537 + P ++P P+P P PPT P SPPTT + P + T P Sbjct: 1627 --TPPT--STTTLPPTTTPSPPPTTTTTPPPTTTP---SPPTTTTPSPP----ITTTTTP 1675 Query: 538 EQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLL-VP 596 PP +P SP T P P T + TP+PT P T PS P Sbjct: 1676 -----PPTT------TPSSPITTTPSPPTTTM-TTPSPTTTPSSPITTTTTPSSTTTPSP 1723 Query: 597 KAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 ++ P+P+ + + ++++P T S + P P Sbjct: 1724 PPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLP 1762 Score = 82.0 bits (201), Expect = 2e-15 Identities = 79/277 (28%), Positives = 97/277 (35%), Gaps = 40/277 (14%) Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCP---PPPFPPMAPPTALLQEEPLFSPRFPFP 438 P + P PP PPP L P PP PP P+ + P P Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450 Query: 439 TVPPAPGVS----PLPAPAAFPPT-----PQSVPS----------PAPTPFPIELLPLGY 479 T P+P +S P P PPT P + PS P TP P P+ Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI-- 1508 Query: 480 SEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQ 539 + PA ++P P+P PPT P SPPTT P T T P Sbjct: 1509 TPPA--STTTLPPTTTPSPPTTTTTTPPPTTTP---SPPTTTPITPPTST---TTLPPTT 1560 Query: 540 ALEPPLVSSTL---LRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVP 596 PP ++T +P P T P P T TP PT PP T P P P Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPS-PPTITTTTPPPTTTPSPPTTTTTTPP-PTTTP 1618 Query: 597 KAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPP 633 +P P S L + P P T + +PP Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTT---TPP 1652 Score = 82.0 bits (201), Expect = 2e-15 Identities = 89/358 (24%), Positives = 122/358 (34%), Gaps = 45/358 (12%) Query: 253 SDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPP 312 S + T T P+ PP + P TP P+ + + P Sbjct: 1439 SPPITTTTTPPPTTTPSPP----ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTP 1494 Query: 313 MPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFL 372 P+ P PP+ +P+ S+ TL P P+ T + P P + + Sbjct: 1495 PPTTTPSPPTTTPITPPA-STTTLPPTTTPSPPTTT-----------TTTPPPTTTPSPP 1542 Query: 373 SSDFLLPEDPKPRLPPP--PVPPPLLHYPPPAKVPGLEPCPPPPFPPM----APPTALLQ 426 ++ + P LPP P PPP PP P P PP PP Sbjct: 1543 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602 Query: 427 EEPLFSPRFPFPTVPPAPG----VSPLPAPAAFPPTPQSVPSPAPTPF---PIELLPLGY 479 P + P PT P+P ++P + PPT + PSP PT P P Sbjct: 1603 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT--TTPSPPPTTTTTPPPTTTPSPP 1660 Query: 480 SEPAFGPCFSMPRGKPPAPSPRGQ---KASPPTLAPATASPPTTAGSNNPCLTQLLTAAK 536 + P + PP +P SPPT T SP TT S + T Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS------PITTTTT 1714 Query: 537 PEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPT----PAPTPPRPP-PGPATLAP 589 P P +T+ + + P T LPPT P T P PP P T +P Sbjct: 1715 PSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSP 1772 Score = 76.6 bits (187), Expect = 9e-14 Identities = 90/348 (25%), Positives = 117/348 (33%), Gaps = 61/348 (17%) Query: 258 TMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFT--NSRLPQPPMPS 315 T T S P+ PP P TP P+ + T + P PP + Sbjct: 1474 TTTPSPPTTTPSPPTTT----TTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTT 1529 Query: 316 NFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSD 375 PP+ +P S T P PP S+ + P P ++ Sbjct: 1530 TTTPPPTTTP------SPPTTTPITPPTSTTTL---------PPTTTPSPPPTTTTTPPP 1574 Query: 376 FLLPEDPKPRLPPPPV-----PPPLLHYPPPAKVPGLEPCPPPPFPP----MAPPTALLQ 426 P P P PP PPP PP P P PP + PPT+ Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1634 Query: 427 EEPLFSPR-------FPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPF-PIELLPLG 478 P +P P PT P+P + P+P P T + P P TP PI P Sbjct: 1635 LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP---PITTTTTPPPTTTPSSPITTTP-- 1689 Query: 479 YSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPE 538 S P PSP +SP T T +P +T + P T +T P Sbjct: 1690 ----------SPPTTTMTTPSPTTTPSSPIT---TTTTPSSTTTPSPPPTT--MTTPSPT 1734 Query: 539 QALEPPLVSSTLL--RSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGP 584 PP + T L + SP T P P + PPT +P P P Sbjct: 1735 TTPSPPTTTMTTLPPTTTSSPLTTTP-LPPSITPPTFSPFSTTTPTTP 1781 Score = 56.2 bits (134), Expect = 1e-07 Identities = 66/276 (23%), Positives = 89/276 (32%), Gaps = 45/276 (16%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 3981 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4039 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 4040 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4098 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 4099 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4158 Query: 567 TFLPPTPAP-----------------TPPRPPPGPATLAPSRPLLVPKAE-RLSPPAPSG 608 T + PTP P TP P G T P+ P AE S P P Sbjct: 4159 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPES 4218 Query: 609 SERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDS 644 S + S SS T + PP ++ P S Sbjct: 4219 STPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPS 4254 Score = 55.1 bits (131), Expect = 3e-07 Identities = 60/227 (26%), Positives = 77/227 (33%), Gaps = 24/227 (10%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 4096 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4154 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGS 523 I P G P P + P P+P G + PPT +TA S Sbjct: 4155 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTGPPTHT-STAPIAELTTS 4212 Query: 524 NNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTP-APTPPR--- 579 N P + + + ++ PL ST L S P E T P TP APT Sbjct: 4213 NPPPES---STPQTSRSTSSPLTESTTLLSTLPP---AIEMTSTAPPSTPTAPTTTSGGH 4266 Query: 580 ---PPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGP 623 PPP T P P S P PS + + + P P Sbjct: 4267 TLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313 Score = 53.5 bits (127), Expect = 8e-07 Identities = 55/209 (26%), Positives = 78/209 (37%), Gaps = 31/209 (14%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 4119 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 4171 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540 P P + P P+P G + PPT T++ P + +L T+ P ++ Sbjct: 4172 TPTTTP-ITTTTTVTPTPTPTGTQTGPPT---HTSTAP---------IAELTTSNPPPES 4218 Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPT---PAPTPPRPPPGPATLAPSRPLLVPK 597 P ST SP + T+ + LPP + PP P P T + L P Sbjct: 4219 STPQTSRST--SSPLTESTTL----LSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP 4272 Query: 598 AERLSPPAPSGSERRLSGDLSSMPGPGTL 626 + SPP R + SS P P T+ Sbjct: 4273 STTTSPPGT--PTRGTTTGSSSAPTPSTV 4299 Score = 50.4 bits (119), Expect = 7e-06 Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 1957 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2015 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 2016 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2074 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 2075 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2134 Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 T + PTP PT + P P P P P ++P P P+G++ Sbjct: 2135 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2193 Score = 50.4 bits (119), Expect = 7e-06 Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 2141 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2199 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 2200 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2258 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 2259 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2318 Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 T + PTP PT + P P P P P ++P P P+G++ Sbjct: 2319 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2377 Score = 50.4 bits (119), Expect = 7e-06 Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 2384 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2442 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 2443 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2502 Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 T + PTP PT + P P P P P ++P P P+G++ Sbjct: 2503 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2561 Score = 50.4 bits (119), Expect = 7e-06 Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 2509 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2567 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 2568 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2626 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 2627 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2686 Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 T + PTP PT + P P P P P ++P P P+G++ Sbjct: 2687 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2745 Score = 50.4 bits (119), Expect = 7e-06 Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2751 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2810 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 2811 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2870 Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 T + PTP PT + P P P P P ++P P P+G++ Sbjct: 2871 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2929 Score = 50.4 bits (119), Expect = 7e-06 Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 2936 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2994 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3054 Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 T + PTP PT + P P P P P ++P P P+G++ Sbjct: 3055 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3113 Score = 50.4 bits (119), Expect = 7e-06 Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 3120 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3178 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 3179 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3238 Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 T + PTP PT + P P P P P ++P P P+G++ Sbjct: 3239 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3297 Score = 50.4 bits (119), Expect = 7e-06 Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3303 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 3304 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3362 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 3363 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3422 Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 T + PTP PT + P P P P P ++P P P+G++ Sbjct: 3423 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3481 Score = 50.4 bits (119), Expect = 7e-06 Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 3488 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3546 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 3547 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3606 Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 T + PTP PT + P P P P P ++P P P+G++ Sbjct: 3607 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3665 Score = 50.4 bits (119), Expect = 7e-06 Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 3613 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3671 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 3672 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3730 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 3731 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3790 Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 T + PTP PT + P P P P P ++P P P+G++ Sbjct: 3791 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3849 Score = 50.4 bits (119), Expect = 7e-06 Identities = 55/239 (23%), Positives = 79/239 (33%), Gaps = 42/239 (17%) Query: 412 PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P T + +P P PT P +P+ PTP + PT P Sbjct: 3797 PTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3855 Query: 472 IELL--------PLGYSEPAFGPCFSMPRGKPPAPSPRGQKA--SPPTLAPATASP-PTT 520 I P G P P + P P+P G + + P T +P PT Sbjct: 3856 ITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3914 Query: 521 AGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPC 566 G+ P T + T P P+ ++T + +P T P Sbjct: 3915 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3974 Query: 567 TFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 T + PTP PT + P P P P P ++P P P+G++ Sbjct: 3975 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4033 Score = 49.3 bits (116), Expect = 1e-05 Identities = 58/242 (23%), Positives = 82/242 (33%), Gaps = 50/242 (20%) Query: 409 PCPPPPFP-----PMAP-PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSV 462 P PP P + P PT + P +P TV P P + P P T + Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952 Query: 463 PSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----P 517 +P PT P G P P + P P+P G + PT P T + Sbjct: 1953 VTPTPT-------PTGTQTPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPT 2002 Query: 518 PTTAGSNNPCLTQLLTAAKPEQALEP---------PLVSSTLLRSPGSP-----QETVPE 563 PT G+ P T + T P P+ ++T + +P T P Sbjct: 2003 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2062 Query: 564 FPCTFLPPTPAPTPPRPP------------PGPATLAPSRPLLVP--KAERLSP-PAPSG 608 T + PTP PT + P P P P P ++P P P+G Sbjct: 2063 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2122 Query: 609 SE 610 ++ Sbjct: 2123 TQ 2124 Score = 48.5 bits (114), Expect = 3e-05 Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 2095 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 2147 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535 P P + P P+P G + PT P T + PT G+ P T + T Sbjct: 2148 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2204 Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581 P P+ ++T + +P T P T + PTP PT + P Sbjct: 2205 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2264 Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 P P P P ++P P P+G++ Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2308 Score = 48.5 bits (114), Expect = 3e-05 Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 2279 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 2331 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535 P P + P P+P G + PT P T + PT G+ P T + T Sbjct: 2332 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2388 Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581 P P+ ++T + +P T P T + PTP PT + P Sbjct: 2389 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2448 Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 P P P P ++P P P+G++ Sbjct: 2449 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2492 Score = 48.5 bits (114), Expect = 3e-05 Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 2463 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 2515 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535 P P + P P+P G + PT P T + PT G+ P T + T Sbjct: 2516 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2572 Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581 P P+ ++T + +P T P T + PTP PT + P Sbjct: 2573 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2632 Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 P P P P ++P P P+G++ Sbjct: 2633 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2676 Score = 48.5 bits (114), Expect = 3e-05 Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 2699 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535 P P + P P+P G + PT P T + PT G+ P T + T Sbjct: 2700 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756 Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581 P P+ ++T + +P T P T + PTP PT + P Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2816 Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 P P P P ++P P P+G++ Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2860 Score = 48.5 bits (114), Expect = 3e-05 Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 2883 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535 P P + P P+P G + PT P T + PT G+ P T + T Sbjct: 2884 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2940 Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581 P P+ ++T + +P T P T + PTP PT + P Sbjct: 2941 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3000 Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 P P P P ++P P P+G++ Sbjct: 3001 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3044 Score = 48.5 bits (114), Expect = 3e-05 Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3067 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535 P P + P P+P G + PT P T + PT G+ P T + T Sbjct: 3068 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3124 Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581 P P+ ++T + +P T P T + PTP PT + P Sbjct: 3125 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3184 Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 P P P P ++P P P+G++ Sbjct: 3185 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3228 Score = 48.5 bits (114), Expect = 3e-05 Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3251 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535 P P + P P+P G + PT P T + PT G+ P T + T Sbjct: 3252 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3308 Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581 P P+ ++T + +P T P T + PTP PT + P Sbjct: 3309 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3368 Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 P P P P ++P P P+G++ Sbjct: 3369 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3412 Score = 48.5 bits (114), Expect = 3e-05 Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 3383 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3435 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535 P P + P P+P G + PT P T + PT G+ P T + T Sbjct: 3436 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3492 Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581 P P+ ++T + +P T P T + PTP PT + P Sbjct: 3493 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3552 Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 P P P P ++P P P+G++ Sbjct: 3553 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3596 Score = 48.5 bits (114), Expect = 3e-05 Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 3567 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3619 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535 P P + P P+P G + PT P T + PT G+ P T + T Sbjct: 3620 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3676 Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581 P P+ ++T + +P T P T + PTP PT + P Sbjct: 3677 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3736 Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 P P P P ++P P P+G++ Sbjct: 3737 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3780 Score = 48.5 bits (114), Expect = 3e-05 Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 3751 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3803 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535 P P + P P+P G + PT P T + PT G+ P T + T Sbjct: 3804 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3860 Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581 P P+ ++T + +P T P T + PTP PT + P Sbjct: 3861 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3920 Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 P P P P ++P P P+G++ Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3964 Score = 48.5 bits (114), Expect = 3e-05 Identities = 53/224 (23%), Positives = 76/224 (33%), Gaps = 44/224 (19%) Query: 421 PTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 PT + P +P TV P P + P P T + +P PT P G Sbjct: 3935 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQ 3987 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAA 535 P P + P P+P G + PT P T + PT G+ P T + T Sbjct: 3988 TPTTTP-ITTTTTVTPTPTPTGTQT--PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4044 Query: 536 KPEQALEP---------PLVSSTLLRSPGSP-----QETVPEFPCTFLPPTPAPTPPRPP 581 P P+ ++T + +P T P T + PTP PT + P Sbjct: 4045 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4104 Query: 582 ------------PGPATLAPSRPLLVP--KAERLSP-PAPSGSE 610 P P P P ++P P P+G++ Sbjct: 4105 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4148 Score = 36.6 bits (83), Expect = 0.098 Identities = 57/242 (23%), Positives = 80/242 (33%), Gaps = 45/242 (18%) Query: 388 PPPVPPPLLHYPPP----AKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPA 443 P P P PP A + L PPP P T+ PL T+PPA Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPP-ESSTPQTSRSTSSPLTESTTLLSTLPPA 4244 Query: 444 PGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQ 503 + + PP+ + P+ + P + P P G AP+P Sbjct: 4245 -----IEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTP--- 4296 Query: 504 KASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPE 563 S +A PT + P + + T +P + L+ L + +P E V Sbjct: 4297 --STVQTTTTSAWTPTPTPLSTPSIIRT-TGLRPYPS--SVLICCVLNDTYYAPGEEVYN 4351 Query: 564 -------------FPCTF------LPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPP 604 CT P TP+PTP P +T PS+P P S P Sbjct: 4352 GTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPT---PSKSTPTPSKPSSTP-----SKP 4403 Query: 605 AP 606 P Sbjct: 4404 TP 4405 Score = 33.1 bits (74), Expect = 1.1 Identities = 50/215 (23%), Positives = 62/215 (28%), Gaps = 38/215 (17%) Query: 258 TMTQSGPSPLQL---PPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMP 314 T T P+P P + + P TP I+ T + P P Sbjct: 4134 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4193 Query: 315 SNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSS 374 P + + + L +S PP SS Q S PL S L S Sbjct: 4194 QTGPPTHTSTAPIAELTTSNP-----PPESSTP---------QTSRSTSSPLTESTTLLS 4239 Query: 375 DFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPR 434 L P PP P P G PPP +PP Sbjct: 4240 T-LPPAIEMTSTAPPSTPTA------PTTTSGGHTLSPPPSTTTSPPGT----------- 4281 Query: 435 FPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTP 469 PT G S P P+ T S +P PTP Sbjct: 4282 ---PTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 85.9 bits (211), Expect = 1e-16 Identities = 92/316 (29%), Positives = 122/316 (38%), Gaps = 62/316 (19%) Query: 337 GPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLL 396 GP +PPAS + + S + AR + P P PPPP PPP Sbjct: 142 GPLIPPASPRLGNTS-EAHGAARTA-----------------PPRPNVPAPPPPTPPP-- 181 Query: 397 HYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFP 456 PPPP PP P ++ ++ PL SP P T P V+P P P A P Sbjct: 182 --------------PPPPLPPPLPSSSPIKT-PLVSPPGPL-TKGNLPVVAP-PVPCAPP 224 Query: 457 PTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATAS 516 P P P P PTP P+ + S+ A P + P PP P P PP P + Sbjct: 225 PPP---PPPPPTPPPLPPASV-LSDKAVKPQLA-PLHLPPIPPPL--PLLPPCGYPGLKA 277 Query: 517 PPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPG-SPQETVPEFPCTFLPPTPAP 575 P A+ + A EPP L SP+ ++P P + + Sbjct: 278 EP---------------ASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSET 322 Query: 576 TPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 PP PP P+ AP P +PPAP GS+ L PG G + P P Sbjct: 323 PPPLPPKSPSFQAP--PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPP 380 Query: 636 ILSRGRPDSNKNRRIT 651 S S+K+++ T Sbjct: 381 ARSPTTELSSKSQQAT 396 Score = 72.4 bits (176), Expect = 2e-12 Identities = 95/327 (29%), Positives = 116/327 (35%), Gaps = 69/327 (21%) Query: 308 LPQPPMPSNFPEP-------PSFSPVVDSLFS------SGTLGPEVPPASSAMTHLSGHS 354 +P PP P+ P P PS SP+ L S G L PP A Sbjct: 171 VPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP-----P 225 Query: 355 RLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLE------ 408 P PL ++ LS + P+ LPP P P PLL PP PGL+ Sbjct: 226 PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLL---PPCGYPGLKAEPASP 282 Query: 409 -------PCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGV-SPLPAPAAFPPTPQ 460 P PPPP PP A SPR P PP PGV S P PP Sbjct: 283 AQDAQEPPAPPPPLPPYAS----------CSPRASLP-APPLPGVNSSSETPPPLPPKSP 331 Query: 461 SVPSPAPTPFPIELLPLGYSEPAFGPCFSMPR-GKPPAPSPRGQKASPPTLAPATASPPT 519 S +P P + LP + P P R G+P A G K +PP AP SP T Sbjct: 332 SFQAP-PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGA---GGGKLNPPP-APPARSPTT 386 Query: 520 TAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPR 579 S +Q TA P Q L + +L + +F F + PP Sbjct: 387 ELSSK----SQQATAWTPTQQPGGQLRNGSL--------HIIDDFESKFTFHSVEDFPP- 433 Query: 580 PPPGPATLAPSRPLLVPKAERLSPPAP 606 P P + + K R P P Sbjct: 434 ----PDEYKPCQKIYPSKIPRSRTPGP 456 Score = 69.7 bits (169), Expect = 1e-11 Identities = 75/304 (24%), Positives = 109/304 (35%), Gaps = 59/304 (19%) Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQE-EPLFSPRF----- 435 P P PPPP+PPP PPP P P PPP PP++ T+ L+ +P Sbjct: 2 PVPPPPPPPLPPP----PPPLGAP---PPPPPSAPPVSTDTSSLRRADPKGRSALLADIQ 54 Query: 436 --------------PFPTVPPAPGVSPLPAPAAFP---PTPQSVPSPAPTPFPIELLPLG 478 P + + G + +A TP ++ FP+ L P G Sbjct: 55 QGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPV-LRPAG 113 Query: 479 YSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLL------ 532 + A G P + P+P + S P + PA+ T+ ++ T Sbjct: 114 QRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPA 173 Query: 533 ----TAAKPEQALEPPLVSSTLLRSP----------GSPQETVPEFPCTFLPPTPAPTPP 578 T P L PPL SS+ +++P G+ P PC PP P P P Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPT 233 Query: 579 RPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILS 638 PP PA++ + + A PP P L +P G ++ P P Sbjct: 234 PPPLPPASVLSDKAVKPQLAPLHLPPIPP--------PLPLLPPCGYPGLKAEPASPAQD 285 Query: 639 RGRP 642 P Sbjct: 286 AQEP 289 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 84.7 bits (208), Expect = 3e-16 Identities = 105/347 (30%), Positives = 133/347 (38%), Gaps = 50/347 (14%) Query: 311 PPMPSNFPEPP-SFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSS 369 P + +FP+P SF+PV+ PP S+ M +G + P PL Sbjct: 693 PSLQQHFPDPAMSFAPVL-------------PPPSTPMP--TGPGQPAPPGQQPPPLAQP 737 Query: 370 AFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEP 429 L P+P +P PVPP L Y PA G P P AP L Q P Sbjct: 738 TPLPQVLA----PQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPP 793 Query: 430 LFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPF-PIELLP-LGYSEPAFGPC 487 P P + P G+ LP PT P P P F P +LP L P P Sbjct: 794 QMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPA 853 Query: 488 FSM-------PRGKPPAPSPRGQKASPPTLAP--ATASPPTTAGSNNPCLTQLLTAAKPE 538 + P G P A R + P P A A P A S + + QL P Sbjct: 854 LPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQL-----PG 908 Query: 539 QALEP---PLVSSTLLRSPGSPQETVPEFPCTFLPPTPA----PT-PPRPPPGPATLAPS 590 Q + P P ++ T + P SP TV T PP PA PT PP+P P P Sbjct: 909 QPVYPAAFPQMAPTDV--PPSPHHTVQNMRAT--PPQPALPPQPTLPPQPVLPPQPTLPP 964 Query: 591 RPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPIL 637 +P+L P+ R PP P + + +P L VR P QP L Sbjct: 965 QPVLPPQPTR--PPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHL 1009 Score = 76.3 bits (186), Expect = 1e-13 Identities = 127/465 (27%), Positives = 161/465 (34%), Gaps = 113/465 (24%) Query: 266 PLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPE------ 319 P P E VG+ D + PLQ + + + P PP P PE Sbjct: 548 PALQPKEQQDVGSPDKARGPPVPLQVQVT-------YHAQAGQPGPPEPEE-PEADQHLL 599 Query: 320 PPSF-----SPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNS-----CPGPLDSS 369 PP+ S DS F SG + S+ + S A S C P+ Sbjct: 600 PPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEG 659 Query: 370 AFLSSDF----------LLPEDPKPRLPPPPVPPPLL-HYPPPAKVPGLEPCPPPPFPPM 418 L P P +P P PP L H+P PA P PPP PM Sbjct: 660 PVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAM--SFAPVLPPPSTPM 717 Query: 419 -------APPTALLQEEPLFSPRFPFPTV-PPAPGVSPLPAPAAFPP--TPQS-VPSPA- 466 APP Q+ P + P P V P P V P P PP P S V +PA Sbjct: 718 PTGPGQPAPPG---QQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQ 774 Query: 467 --PTPFP-IELLPLGYSEPAFGPCFSMP--------RGKPPA----------PSPRGQKA 505 P P L PL P P +P G PPA P P Q Sbjct: 775 LKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYF 834 Query: 506 SPPTLAPATASP-----------------PTTAGSNNPCLTQL--LTAAKPEQALEPPLV 546 SP + P+ A+P P A PC T + A P A+ PP V Sbjct: 835 SPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGV 894 Query: 547 SSTLLRS-----PGSP--QETVPEFPCTFLPPTP-------APTPPRPPPGPATLAPSRP 592 ++ + S PG P P+ T +PP+P TPP+P P P +P Sbjct: 895 AALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQP 954 Query: 593 LLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPIL 637 +L P + PP P L + P P + PPQP+L Sbjct: 955 VLPP--QPTLPPQPV-----LPPQPTRPPQPVLPPQPMLPPQPVL 992 Score = 70.9 bits (172), Expect = 5e-12 Identities = 98/384 (25%), Positives = 138/384 (35%), Gaps = 75/384 (19%) Query: 311 PPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSA 370 PP+ P P +P + + P +PP + + + ++L+ PL A Sbjct: 732 PPLAQPTPLPQVLAP--QPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLA 789 Query: 371 FLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPC----PPPPFPPMAPPT---- 422 + P++PP PV PP+ P A + GL P P PP+ PP Sbjct: 790 QVP----------PQMPPIPVVPPIT---PLAGIDGLPPALPDLPTATVPPVPPPQYFSP 836 Query: 423 -----ALLQEEPLFSPRFPFPTVP-PAPGVSPLPAPAA--FPPTPQSVPSPAPTPFPIEL 474 +L P SP P V P P +PL P P P ++P A P + Sbjct: 837 AVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAA 896 Query: 475 LPLGYS------EPAFGPCFSM--PRGKPPAP--SPRGQKASPP--------TLAPATAS 516 L + + +P + F P PP+P + + +A+PP TL P Sbjct: 897 LSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVL 956 Query: 517 PPTTAGSNNPCLTQLLT-----AAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPP 571 PP P L T P+ L P V P P+ P P P Sbjct: 957 PPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPA 1016 Query: 572 T----------PAP--------TPPRPPPGPATLAPSRP-LLVPKAERLSPPAPSGSERR 612 PAP P P P A L+P P +L+P A L P PS S Sbjct: 1017 ATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPS-SLAT 1075 Query: 613 LSGDLSSMP-GPGTLSVRVSPPQP 635 +S + S+P TL +PP P Sbjct: 1076 VSASVQSVPTQTATLLPPANPPLP 1099 Score = 64.7 bits (156), Expect = 3e-10 Identities = 91/326 (27%), Positives = 118/326 (36%), Gaps = 53/326 (16%) Query: 307 RLPQPP-----MPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNS 361 +LP PP MP P + P L + G SA+ L G A Sbjct: 860 KLPHPPGAPLAMPCRTIVPNA--PATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFP 917 Query: 362 CPGPLD--SSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMA 419 P D S + + P+P LPP P PP +P PP P Sbjct: 918 QMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPP-------------QPVLPPQ--PTL 962 Query: 420 PPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPA--PTPFPIELLPL 477 PP +L P PT PP P + P P PP P P PA P P++ Sbjct: 963 PPQPVLP---------PQPTRPPQPVLPPQP---MLPPQPVLPPQPALPVRPEPLQPHLP 1010 Query: 478 GYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKP 537 + PA P + G PAP A PT+ P A +P L ++L A P Sbjct: 1011 EQAAPAATPGSQILLGH-PAPYAVDVAAQVPTV------PVPPAAVLSPPLPEVLLPAAP 1063 Query: 538 EQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP---PPGPATLAPSRPLL 594 E L P SS L + + ++VP T LPP P P P P P P+ Sbjct: 1064 E--LLPQFPSS--LATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQ 1119 Query: 595 VPKAERLSPPA-PSGSERRLSGDLSS 619 +A + PP P E D++S Sbjct: 1120 EEQASQDKPPGLPQSCESYGGSDVTS 1145 Score = 49.7 bits (117), Expect = 1e-05 Identities = 69/235 (29%), Positives = 78/235 (33%), Gaps = 48/235 (20%) Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPG------LEPCPPPPF--------------PPMA 419 E P P P P PL PP A L P F PP A Sbjct: 1320 EHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGA 1379 Query: 420 PPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAA-------FPPTPQSVPSPAPTPFPI 472 PP L P P P AP S +P PA+ P TPQ + S T P+ Sbjct: 1380 PPAPLAPSSP---PVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPL 1436 Query: 473 ---ELLPLGYSEPAFG--PCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPC 527 PL G PC P A S R A L P P +G+ P Sbjct: 1437 AETHEAPLAVQPLVVGLAPCTPAPE----AASTRDASAPREPLPPPAPEPSPHSGTPQPA 1492 Query: 528 LTQ---LLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPR 579 L Q LL AA + L +S L P P TVP P + L PPR Sbjct: 1493 LGQPAPLLPAAVGAVS----LATSQLPSPPLGP--TVPPQPPSALESDGEGPPPR 1541 Score = 47.8 bits (112), Expect = 4e-05 Identities = 64/245 (26%), Positives = 84/245 (34%), Gaps = 37/245 (15%) Query: 394 PLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFP-FPTVPPAPGVSPLPAP 452 P+ +P P P P PP A + ++ L S P F + P Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNP 1376 Query: 453 AAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTL-A 511 PP P + SP P+ LP + PA +MP S G +P L + Sbjct: 1377 PGAPPAPLAPSSP-----PVTALPQDGAAPATS---TMPEPASGTASQAGGPGTPQGLTS 1428 Query: 512 PATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPP 571 S P P Q L P S+ R +P+E +P PP Sbjct: 1429 ELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAAST---RDASAPREPLP-------PP 1478 Query: 572 TPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMP-GPGTLSVRV 630 P P+P P PA P+ PLL PA G+ + L S P GP Sbjct: 1479 APEPSPHSGTPQPALGQPA-PLL---------PAAVGAVSLATSQLPSPPLGP------T 1522 Query: 631 SPPQP 635 PPQP Sbjct: 1523 VPPQP 1527 Score = 44.7 bits (104), Expect = 4e-04 Identities = 108/448 (24%), Positives = 150/448 (33%), Gaps = 73/448 (16%) Query: 262 SGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPP 321 S P PL P +A +A + QPS F+ + + PP P P Sbjct: 1330 SPPLPLSSLPPEASQDSAPYKDQLSSKEQPS---FLASQQLLSQAGPSNPPGAPPAPLAP 1386 Query: 322 SFSPVV----DSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDF- 376 S PV D + + PE PAS + G Q S L++S L+ Sbjct: 1387 SSPPVTALPQDGAAPATSTMPE--PASGTASQAGGPGTPQGLTS---ELETSQPLAETHE 1441 Query: 377 -----------LLPEDPKPRL--------PPPPVPPPLLHYPPPAKVPGLEPCPPPPFPP 417 L P P P P P+PPP P + P P P P Sbjct: 1442 APLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLP 1501 Query: 418 MAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPL 477 A L L SP PTVPP P S L + PP +L L Sbjct: 1502 AAVGAVSLATSQLPSPPLG-PTVPPQP-PSALESDGEGPPPRVGFVDSTIKSLDEKLRTL 1559 Query: 478 GYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKP 537 Y E P S G P R TL P P + C L P Sbjct: 1560 LYQEHV--PTSSASAGTPVEVGDRDF-----TLEPLRGDQP----RSEVCGGDLALPPVP 1608 Query: 538 EQAL-------EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPG------- 583 ++A+ +P + S L + G+ E T A + PR G Sbjct: 1609 KEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMT------AESSPRSMLGYDRDGRQ 1662 Query: 584 ---PATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGP---GTLSVRVSPPQPIL 637 + + PS P VP R + P+ + +G+ S+ P P GT+ + S PQ + Sbjct: 1663 VASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLG 1722 Query: 638 SR--GRPDSNKNRRITHISAEQKRRFNI 663 +R G P ++ A+ RF++ Sbjct: 1723 ARALGSPRKRPEQQDVSSPAKTVGRFSV 1750 Score = 42.7 bits (99), Expect = 0.001 Identities = 39/142 (27%), Positives = 56/142 (39%), Gaps = 30/142 (21%) Query: 498 PSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP 557 P+P ++SPP P ++ PP + + P QL + +P ++S L S P Sbjct: 1322 PAPEAPESSPPL--PLSSLPPEASQDSAPYKDQLSSKEQPS------FLASQQLLSQAGP 1373 Query: 558 QETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDL 617 PP PP P LAPS P + + + PA S SG Sbjct: 1374 SN-----------------PPGAPPAP--LAPSSPPVTALPQDGAAPATSTMPEPASGTA 1414 Query: 618 SSMPGPGT---LSVRVSPPQPI 636 S GPGT L+ + QP+ Sbjct: 1415 SQAGGPGTPQGLTSELETSQPL 1436 Score = 30.0 bits (66), Expect = 9.2 Identities = 26/83 (31%), Positives = 29/83 (34%), Gaps = 11/83 (13%) Query: 405 PGLE----PCPPPPFPP------MAPPTALLQEEPLFSPRFPFPTVPPA-PGVSPLPAPA 453 PGLE P P PP P + L+ E P P P A PG PA A Sbjct: 55 PGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADA 114 Query: 454 AFPPTPQSVPSPAPTPFPIELLP 476 P P P P +E P Sbjct: 115 GPEPVGTQEPGPDPIAAAVETAP 137 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 84.0 bits (206), Expect = 5e-16 Identities = 78/271 (28%), Positives = 101/271 (37%), Gaps = 29/271 (10%) Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEP----CPPPPFPPMAPPTALLQEEPLFSPRF 435 E + +LPPPP+ PP PPP P P CPPPP PP++PP PL Sbjct: 395 EKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPP-PPVSPP-------PL----- 441 Query: 436 PFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRG-K 494 P P PPA P P T P L P +E + P G Sbjct: 442 PSPPPPPAQEEQEESPPPVVPATCSRKRGRPP------LTPSQRAERE--AARAGPEGTS 493 Query: 495 PPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPP--LVSSTLLR 552 PP P+P PP +P A TT N + +A+ + ++ P + + Sbjct: 494 PPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPK 553 Query: 553 SPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERR 612 P V P T PP P P P P A PS P+ +P+ R P+ Sbjct: 554 PPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTS 613 Query: 613 LSGDL-SSMPGPGTLSVRVSPPQPILSRGRP 642 L+ +L P P PP P S RP Sbjct: 614 LTRELPPPPPAPPPPPAPSPPPAPATSSRRP 644 Score = 63.9 bits (154), Expect = 6e-10 Identities = 96/365 (26%), Positives = 123/365 (33%), Gaps = 76/365 (20%) Query: 306 SRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGP 365 ++LP PP+ P PP P +PP S+ S P P Sbjct: 399 AKLPPPPLTPPAPSPP----------------PPLPPPST---------------SPPPP 427 Query: 366 LDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMA------ 419 L P P P + PPP+P P PPP E PPP P Sbjct: 428 L-----------CPPPPPP-VSPPPLPSP----PPPPAQEEQEESPPPVVPATCSRKRGR 471 Query: 420 PPTALLQEEPLFSPRF-PFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPF--PIELLP 476 PP Q + R P T PP P +P A PP +P T F I Sbjct: 472 PPLTPSQRAEREAARAGPEGTSPPTP--TPSTATGG-PPEDSPTVAPKSTTFLKNIRQFI 528 Query: 477 LGYSEPAFGPCFSMPRG--KPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTA 534 + PR P P + SP P T SPP P + Sbjct: 529 MPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQ-EPAPVPSPPRAP 587 Query: 535 AKPEQALEPPLVSSTLLRSPGSPQETVP-EFPCTFLPPTPAPTP---PRPPPGPATLAPS 590 P + P ++LR P ++ E P PP PAP P P PPP PAT + Sbjct: 588 TPPSTPVPLPEKRRSILREPTFRWTSLTRELP----PPPPAPPPPPAPSPPPAPAT-SSR 642 Query: 591 RPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSV-RVSPPQPILSRGRPDSNKNRR 649 RPLL+ R PS + ++ + + P G PP S P+ R Sbjct: 643 RPLLL----RAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGR 698 Query: 650 ITHIS 654 H+S Sbjct: 699 TNHLS 703 Score = 59.7 bits (143), Expect = 1e-08 Identities = 63/238 (26%), Positives = 84/238 (35%), Gaps = 29/238 (12%) Query: 381 DPKPRLPP-----PPVPPPLLHYPPPAKVPGLEPCPP-PPFPPMAP-PTALLQEEPLFSP 433 D P PP P + PP+ PP + P P PP P PP P P + L P Sbjct: 548 DEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREP 607 Query: 434 RFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPC------ 487 F + ++ LP P PP P + PSP P P PL P F P Sbjct: 608 TFRWTSL-----TRELPPPPPAPPPPPA-PSPPPAPATSSRRPLLLRAPQFTPSEAHLKI 661 Query: 488 FSMPRGKPPAPSPRGQKASPPTLAPATASP-PTTAGSNN----PCLTQLLTAAKPEQALE 542 + PP +P + PP + A P P G N P ++T P +A Sbjct: 662 YESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTT--PVKAEV 719 Query: 543 PPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAER 600 P + L P + + + P PP P P P P +P E+ Sbjct: 720 SPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPP---PQPQLQPPPSPQQMPPLEK 774 Score = 56.6 bits (135), Expect = 9e-08 Identities = 85/333 (25%), Positives = 114/333 (34%), Gaps = 75/333 (22%) Query: 382 PKPRLPPPPVP---PPLLHYPPPAKVPGLEPCPPPPF----------PPMAPPTALLQEE 428 P P PPPP P PPL PPP E PPP PP+ P +E Sbjct: 425 PPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREA 484 Query: 429 PLFSPRF---PFPTVPPAPGVSPLPAPAAFPP-------------------------TPQ 460 P P PT A G P +P P TP+ Sbjct: 485 ARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPR 544 Query: 461 S-VPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAP------A 513 + P P +E+ P+ P +P+ P PSP P T P + Sbjct: 545 RFMDEDPPKPPKVEVSPV--LRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRS 602 Query: 514 TASPPTTAGSNNPCLTQLLT----AAKPEQALEPPLVSST------LLRSPG-SPQETVP 562 PT ++ LT+ L A P A PP +T LLR+P +P E Sbjct: 603 ILREPTFRWTS---LTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHL 659 Query: 563 EFPCTFLPPTPAPTP----PRPPPGPATLAPSRPLLVPKAERLSPP-------APSGSER 611 + + L P P P P PPP + A P V + LS P P +E Sbjct: 660 KIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEV 719 Query: 612 RLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDS 644 G + GP T + + P Q + ++ P + Sbjct: 720 SPHGAPALSNGPQTQAQLLQPLQALQTQLLPQA 752 Score = 49.3 bits (116), Expect = 1e-05 Identities = 55/191 (28%), Positives = 78/191 (40%), Gaps = 29/191 (15%) Query: 395 LLHYPPPA-KVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPA 453 ++H P P+ + PG E PP + P A + P+ + P + P G +P PAP Sbjct: 1804 IVHSPAPSSEPPGGED--PPLDTDVLVPGAPERHSPIQNLD---PPLRPDSGSAPPPAPR 1858 Query: 454 AFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLA-P 512 +F VP+ +P+ P+ +FGP P SP PT+ P Sbjct: 1859 SFSGARIKVPNYSPSRRPL-------GGVSFGPL-------PSPGSPSSLTHHIPTVGDP 1904 Query: 513 ATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCT---FL 569 +PP + +P L P + PPL +S LR P P V T Sbjct: 1905 DFPAPPRRSRRPSP----LAPRPPPSRWASPPLKTSPQLRVP-PPTSVVTALTPTSGELA 1959 Query: 570 PPTPAPTPPRP 580 PP PAP+PP P Sbjct: 1960 PPGPAPSPPPP 1970 Score = 48.9 bits (115), Expect = 2e-05 Identities = 96/385 (24%), Positives = 126/385 (32%), Gaps = 69/385 (17%) Query: 276 VGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGT 335 V +A + P TP P ++ + D T+S P PPS P V G Sbjct: 2041 VVSAPGLAPSATPGAPRIEQLDGVDDG-TDSEAEAVQQPRGQGTPPS-GPGVVRAGVLGA 2098 Query: 336 LGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLP-------EDPKPRLPP 388 G P + + + GP D A + L P P L Sbjct: 2099 AGDRARPPEDLPSEIVDF----VLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTA 2154 Query: 389 PPVPPPL----LHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAP 444 P P L P +V L P P PP P + + + +F V A Sbjct: 2155 SPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVF--------VKMAG 2206 Query: 445 GVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFG--PCFSMPRGKPPAPSP-- 500 P+P P PP P ++ APT + LP G P G P + R PP P P Sbjct: 2207 EGEPVPPPVKQPPLPPTISPTAPTSW---TLPPG---PLLGVLPVVGVVRPAPPPPPPPL 2260 Query: 501 ----RGQKASPPTLAP--------ATASPPT-------------TAGSNNPCLTQLLTAA 535 ASPP A + SPP A + P + L + Sbjct: 2261 TLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGG 2320 Query: 536 KPEQALEPPLVSSTL-LRSPGSP---QETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591 ++ P V L L PG P + P + L P P PP+ P GP L Sbjct: 2321 FSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDL---- 2376 Query: 592 PLLVPKAERLSPPAPSGSERRLSGD 616 LL + S A S E S D Sbjct: 2377 -LLESQWHHYSGEASSSEEEPPSPD 2400 Score = 46.2 bits (108), Expect = 1e-04 Identities = 78/309 (25%), Positives = 104/309 (33%), Gaps = 59/309 (19%) Query: 270 PPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPP---MPSNFPEPPSF--S 324 PPED+ + P T ++ F+ +SR+ + P M + P+PP S Sbjct: 506 PPEDS-----PTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVS 560 Query: 325 PVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDS---SAFLSSDF----- 376 PV+ ++ PP + R S P PL S F Sbjct: 561 PVLRPPITTS------PPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSL 614 Query: 377 ---LLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSP 433 L P P P PP P PPP + P P + ++L PL +P Sbjct: 615 TRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAP 674 Query: 434 RFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRG 493 P P PPA P P A T S+PR Sbjct: 675 EAPEPEPPPADDSPAEPEPRAVGRTNH---------------------------LSLPRF 707 Query: 494 KPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRS 553 P +P + SP APA ++ P T L L T P QAL PP L+ Sbjct: 708 APVVTTPVKAEVSPHG-APALSNGPQTQAQLLQPLQALQTQLLP-QALPPP---QPQLQP 762 Query: 554 PGSPQETVP 562 P SPQ+ P Sbjct: 763 PPSPQQMPP 771 Score = 45.1 bits (105), Expect = 3e-04 Identities = 53/182 (29%), Positives = 73/182 (40%), Gaps = 15/182 (8%) Query: 462 VPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTA 521 V SPAP+ P G +P +P G P SP Q PP + ++PP Sbjct: 1805 VHSPAPSSEPP-----GGEDPPLDTDVLVP-GAPERHSPI-QNLDPPLRPDSGSAPPPAP 1857 Query: 522 GSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP 581 S + ++ + + L VS L SPGSP P P PA PPR Sbjct: 1858 RSFSGARIKVPNYSPSRRPLGG--VSFGPLPSPGSPSSLTHHIPTVGDPDFPA--PPRRS 1913 Query: 582 PGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGR 641 P+ LAP RP P + SPP + + R+ S + S ++PP P S Sbjct: 1914 RRPSPLAP-RP---PPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPP 1969 Query: 642 PD 643 P+ Sbjct: 1970 PE 1971 Score = 42.7 bits (99), Expect = 0.001 Identities = 30/102 (29%), Positives = 41/102 (40%), Gaps = 20/102 (19%) Query: 554 PGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRL 613 P + +E P PP P+P PP PPP + +P PL P +SPP Sbjct: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPP---STSPPPPLCPPPPPPVSPP--------- 439 Query: 614 SGDLSSMPGPGTLSVRVSPPQPIL------SRGRPDSNKNRR 649 L S P P + P P++ RGRP ++R Sbjct: 440 --PLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQR 479 Score = 40.4 bits (93), Expect = 0.007 Identities = 94/394 (23%), Positives = 128/394 (32%), Gaps = 68/394 (17%) Query: 305 NSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPG 364 N + P PS+ P P P +D+ L P P S + +L R + S P Sbjct: 1801 NQTIVHSPAPSSEP-PGGEDPPLDT----DVLVPGAPERHSPIQNLDPPLRPDS-GSAPP 1854 Query: 365 PLDSSAFLSSDFLLPEDPKPR----------LPPPPVPPPLLHYPPPAKVPGLEPCP--- 411 P S F + +P R LP P P L H+ P P P Sbjct: 1855 PAPRS-FSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRS 1913 Query: 412 --PPPFPPMAPPTALLQEEPLFSP--RFPFPT-----VPPAPGVSPLPAPAAFPPTPQSV 462 P P P PP+ SP R P PT + P G P PA PP P+ + Sbjct: 1914 RRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDL 1973 Query: 463 PSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP-----PAPSPRGQKASPPTLAPATASP 517 P +E++ G S S+ +P A G P + S Sbjct: 1974 ---GPDFEDMEVVS-GLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESS 2029 Query: 518 PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTP 577 PT+ + P P P + G+ E A Sbjct: 2030 PTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSE------------AEAVQQ 2077 Query: 578 PR----PPPGPATLAPSRPLLVPKAERLSPPAPSGSE------RRLSGDLSSMPGPGTLS 627 PR PP GP + +L +R PP SE + L G GP S Sbjct: 2078 PRGQGTPPSGPGVVRAG--VLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREES 2135 Query: 628 VRVSPPQPILSRGRPDSNKNRRITHISAEQKRRF 661 + PP P L+ G S ++ +T A+ R F Sbjct: 2136 L---PPAPPLANG---SQPSQGLTASPADPTRTF 2163 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 83.2 bits (204), Expect = 9e-16 Identities = 115/424 (27%), Positives = 149/424 (35%), Gaps = 76/424 (17%) Query: 262 SGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPP 321 + P PL E++ A +L L P + + D F S P PS FP Sbjct: 721 TAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSST 780 Query: 322 SFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPED 381 P S GP P S T L +Q R PGP +P Sbjct: 781 GPGPHYLS-------GPLPPGTYSGPTQL-----IQPR--APGP----------HAMPVA 816 Query: 382 PKPRLPPPPVPPPLLHYPPPAKVP---------GLEPCPPPPFPPMAPPTALLQEEPLFS 432 P P L P P P L P + G+ P PP P APP E + Sbjct: 817 PGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMA 876 Query: 433 PR----------FPFPT-VPPAPGVSPLPAPAAFP-------PTPQSVPSPAPTPFPIEL 474 R P P+ P P +P P P FP PTP + P+ A P P + Sbjct: 877 VRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQH 936 Query: 475 -----LPLGYSEPAFGPCFSMPRGKPPAPSPRGQKA---SPPTLAPATASP---PTTAGS 523 +P G+ P GP P+ P P P +A PP P P A Sbjct: 937 HFSSGIPAGFPAPRIGP---QPQ---PHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPG 990 Query: 524 NNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPG 583 P + A +P +PP T L PG Q+ +P P+P P P PP Sbjct: 991 LLPPQSPYPYAPQPGVLGQPPPPLHTQLY-PGPAQDPLPAHSGALPFPSPGPPQPPHPPL 1049 Query: 584 PATLAPSRPLLVPKAERLSPPAPSGSER-----RLSGDLSSMPGPGTLSVR--VSPPQPI 636 APS + P+A L+ PS + + L + PGPG + R + P P Sbjct: 1050 AYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPC 1109 Query: 637 LSRG 640 L RG Sbjct: 1110 LRRG 1113 Score = 69.3 bits (168), Expect = 1e-11 Identities = 110/420 (26%), Positives = 146/420 (34%), Gaps = 74/420 (17%) Query: 260 TQSGPSPLQLP---PEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSN 316 + +GP P L P Y G +IQP +P P P+ Sbjct: 778 SSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHA----------------MPVAPGPAL 821 Query: 317 FPEP---------PSFSP---VVDSLFSSGTLGPEVPPA---SSAMTHLSGHSRLQARNS 361 +P P P SP VV S + +GP P A S+ SG A Sbjct: 822 YPAPAYTPELGLVPRSSPQHGVVSSPYVG--VGPAPPVAGLPSAPPPQFSGPELAMAVRP 879 Query: 362 CPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPP 421 +DS +P PR P P PPP P VP +P P P P Sbjct: 880 ATTTVDSI-----QAPIPSHTAPRPNPTPAPPP-----PCFPVPPPQPLPTPYTYPAGAK 929 Query: 422 TALLQEEPLFS---PRFPFPTVPPAPGVSPLPAPA-AFPPTPQSVPSPAPTP--FPIE-- 473 + + S FP P + P P P P P+ AF P P P P P FP + Sbjct: 930 QPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAP 989 Query: 474 -LLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASP---PTLAPATASPPTTAGSNNPCLT 529 LLP P + P + G+PP P P P A + A P + G P Sbjct: 990 GLLPPQSPYP-YAPQPGV-LGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHP 1047 Query: 530 QLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAP 589 L P P + +R P S ++ P L P+PAP+P P P A Sbjct: 1048 PLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPS---PHLVPSPAPSPGPGPVPPRPPAA 1104 Query: 590 SRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNRR 649 P + + + S E + G S PG G QP+L + D+ + RR Sbjct: 1105 EPPPCLRRGAAAADLLSSSPESQHGGTQS--PGGG---------QPLLQPTKVDAAEGRR 1153 Score = 40.8 bits (94), Expect = 0.005 Identities = 32/92 (34%), Positives = 40/92 (43%), Gaps = 23/92 (25%) Query: 387 PPPPVPPPLLHYPPPAKVPGLEPCPPP---PFPPMAPPTALLQEEPLFSPRFPFPTVPPA 443 PP + P+ P PA+ PGL P P P P +PP PL SP +P A Sbjct: 1509 PPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPP-------PLSSP------LPEA 1555 Query: 444 PGVSPLPAPAAFPPTPQSVPSPAPTPFPIELL 475 P P PP P++ PS P +ELL Sbjct: 1556 ------PQPKEEPPVPEA-PSSGPPSSSLELL 1580 Score = 38.1 bits (87), Expect = 0.034 Identities = 30/86 (34%), Positives = 36/86 (41%), Gaps = 8/86 (9%) Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT 439 E P LP P PP L PPA +P P P PP++ P L E P P P Sbjct: 1514 ESPVASLPGPAEPPGL----PPASLPESTPIPSSSPPPLSSP---LPEAPQPKEEPPVPE 1566 Query: 440 VPPA-PGVSPLPAPAAFPPTPQSVPS 464 P + P S L A+ P S+ S Sbjct: 1567 APSSGPPSSSLELLASLTPEAFSLDS 1592 Score = 32.3 bits (72), Expect = 1.9 Identities = 33/128 (25%), Positives = 49/128 (38%), Gaps = 24/128 (18%) Query: 544 PLVSSTLLRSPGSPQETVP-----EFPCTFLPPTPAPTPPRPP----------PGPATLA 588 PL S+++ + PQ++ + P + + T A RPP PGPA Sbjct: 1468 PLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGPAEPP 1527 Query: 589 PSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKNR 648 P +P+ S P PS S LS L P P + PP P P S+ Sbjct: 1528 GLPPASLPE----STPIPSSSPPPLSSPLPEAPQP-----KEEPPVPEAPSSGPPSSSLE 1578 Query: 649 RITHISAE 656 + ++ E Sbjct: 1579 LLASLTPE 1586 Score = 32.0 bits (71), Expect = 2.4 Identities = 34/119 (28%), Positives = 43/119 (36%), Gaps = 13/119 (10%) Query: 491 PRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAK----PEQALEPPLV 546 P KP A + QK P S G + P + T AK P LE P+ Sbjct: 1464 PPCKPLASASISQKNHLPQ-----DSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVA 1518 Query: 547 SST-LLRSPGSPQETVPE---FPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERL 601 S PG P ++PE P + PP +P P P P P P P + L Sbjct: 1519 SLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSSL 1577 Score = 31.2 bits (69), Expect = 4.1 Identities = 44/156 (28%), Positives = 64/156 (41%), Gaps = 15/156 (9%) Query: 212 PPPEQWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISDTLFTMTQSGPSPLQLPP 271 PPP CK L S+ + P++ +L + +S I T+ ++ P L+ P Sbjct: 1463 PPP---CKPLASASISQKNHLPQDSQD--LVLGGDVPISSIQATIAKLSIRPPGGLESPV 1517 Query: 272 EDAYVGNADMIQPDLTPLQ-PSLDDFMDISDFFTNSRLPQPPMP---SNFPEPPSFSPVV 327 + G A+ P L P P S +S LP+ P P PE PS P Sbjct: 1518 A-SLPGPAE--PPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPS 1574 Query: 328 DSLFSSGTLGPEVPPASSAM---THLSGHSRLQARN 360 SL +L PE S++ +S H+ LQA N Sbjct: 1575 SSLELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHN 1610 Score = 31.2 bits (69), Expect = 4.1 Identities = 28/90 (31%), Positives = 37/90 (41%), Gaps = 16/90 (17%) Query: 449 LPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPP 508 L +P A P P P P P E P+ S P P S P P AP P K PP Sbjct: 1513 LESPVASLPGPAEPPGLPPASLP-ESTPIPSSSP---PPLSSPL--PEAPQP---KEEPP 1563 Query: 509 TLAPATASPPTTAGSNNPCLTQLLTAAKPE 538 ++ PP+++ +LL + PE Sbjct: 1564 VPEAPSSGPPSSS-------LELLASLTPE 1586 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 81.6 bits (200), Expect = 3e-15 Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 31/256 (12%) Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPF 437 P++P P P P P P K P P P P P P +E +P+ P Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373 Query: 438 PTVP--PAPGVSPLPAPAAFPPTPQSVPSPAPTPF------PIELLPLGYSEPA----FG 485 PT P+P PAP P + PAPT P E P EPA Sbjct: 374 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 433 Query: 486 PCFSMPRG------KPPAPSPRGQKASPPTLAPATASP----PTTAGSNNPCLTQLLTAA 535 P + P+ K PAP+ + A T PA +P PTT P + LT Sbjct: 434 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 493 Query: 536 KPEQAL----EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591 PE+ E P ++ +P +P+E P P P TP P P PA P Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 553 Query: 592 PLLVPKAERLSPPAPS 607 P E PAP+ Sbjct: 554 PAPTTPKE----PAPT 565 Score = 81.6 bits (200), Expect = 3e-15 Identities = 101/361 (27%), Positives = 131/361 (36%), Gaps = 47/361 (13%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVP-------PASSAMTHLSGHSRLQARNS 361 P+ P P+ EP +P + + P P P A T + + Sbjct: 415 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474 Query: 362 CPGPLDSSAFLSSDFLLPEDPK------PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPF 415 P +A + L P P+ P P P P L P P P P Sbjct: 475 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 534 Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVP--PAPGVSPLPAPAAFPPT-PQSVPSPAPT---- 468 P A P + P +P+ P PT P PAP AP T P ++ PAPT Sbjct: 535 PKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 593 Query: 469 PFPIELLPLGYSEPAFGPCF----SMPRGKPPA----PSPRGQKASPPTLAPATASPPTT 520 P P EL P EP C + P+G P P+P K PT TA PTT Sbjct: 594 PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA--PTT 651 Query: 521 AGSNNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTP---A 574 P T A E A + P +++ +P +P+ET P P P TP A Sbjct: 652 L--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 709 Query: 575 PTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634 PT P PP P T S P + P S + +LS+ P P L SP + Sbjct: 710 PTTPETPP-PTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKAL--ENSPKE 761 Query: 635 P 635 P Sbjct: 762 P 762 Score = 75.5 bits (184), Expect = 2e-13 Identities = 72/284 (25%), Positives = 97/284 (34%), Gaps = 28/284 (9%) Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFP 438 P++P P P P + P K P P P P +E +P+ P P Sbjct: 221 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 280 Query: 439 TV--PPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKP 495 T PAP + P P + PAPT P E P EP P P K Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKE 339 Query: 496 PA------PSPRGQKASPPTL----APATASPPTTAGSNNPCLT------QLLTAAKPEQ 539 PA P+P K PT AP T P + P T T + P Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 399 Query: 540 ALEP-PLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP-------PGPATLAPSR 591 EP P + + +P P T + P P PAPT P+ P P P T Sbjct: 400 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 459 Query: 592 PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 P K +P P+ + + + + T +++P P Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 503 Score = 74.3 bits (181), Expect = 4e-13 Identities = 65/222 (29%), Positives = 80/222 (36%), Gaps = 14/222 (6%) Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT 439 ++P P P P P P K P P P P +E +P+ P PT Sbjct: 378 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 437 Query: 440 VP--PAPGVSPLPAPAA-FPPTPQSVPSPAPTPFPIELLPLGYSEPA------FGPCFSM 490 P PAP PAP P P + PAPT P E P E A P + Sbjct: 438 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT-PKEPAPTTPKETAPTTPKKLTP--TT 494 Query: 491 PRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTL 550 P P + +P LAP T PT P T AA P EP ++ Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPA-PTTPK 552 Query: 551 LRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592 +P +P+E P P P TP T P PA P +P Sbjct: 553 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 594 Score = 69.7 bits (169), Expect = 1e-11 Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 37/345 (10%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQ-----ARNSCP 363 P+ P P+ EP +P + ++ P P + T S + + S P Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412 Query: 364 GPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP-----PPPFPPM 418 + ++ P PK P P P PA EP P P P P Sbjct: 413 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 472 Query: 419 APPTALLQEEPLFSPRFPFPTVPP--APGVSPLPAPAA---------FPPTPQSVPSPAP 467 P +E +P+ PT P AP PAP PTP + PAP Sbjct: 473 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 532 Query: 468 TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTL----APATASPPTTAGS 523 T P P EPA P P+P K + PT AP T P Sbjct: 533 TT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 591 Query: 524 NNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580 P +L E + P ++ +P +P+E P P P TP T P Sbjct: 592 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 651 Query: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGT 625 PA P +P PK L+P G + S P P T Sbjct: 652 LKEPAPTTPKKP--APK--ELAPTTTKGP----TSTTSDKPAPTT 688 Score = 58.9 bits (141), Expect = 2e-08 Identities = 67/217 (30%), Positives = 78/217 (35%), Gaps = 43/217 (19%) Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPC--PPPPFPPMAPPTALLQEEPLFSPRFPF 437 ++P P P P P L P K P C P P P PT + P +P+ P Sbjct: 584 KEPAPTTPKKPAPKELA--PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT-TPKEPA 640 Query: 438 PTVP----------PAPGVSPLPAPAAFPPTPQSVPS------PAPTPFPIELLPLGYSE 481 PT P PAP PAP PT P+ PAPT P E P E Sbjct: 641 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKE 699 Query: 482 PAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQAL 541 PA P P P + S PT T PTT + T L+A +AL Sbjct: 700 PAPTTPKKPAPTTPETPPPTTSEVSTPT----TTKEPTTIHKSPDESTPELSAEPTPKAL 755 Query: 542 EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578 E SP+E P P T TPA T P Sbjct: 756 E------------NSPKE--PGVPTT---KTPAATKP 775 Score = 58.5 bits (140), Expect = 2e-08 Identities = 60/246 (24%), Positives = 90/246 (36%), Gaps = 26/246 (10%) Query: 400 PPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTP 459 P +KV +P P P +E +P+ P T P P + + + P P Sbjct: 189 PTSKVLA-KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247 Query: 460 QSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPA----PSPRGQKASPPT-LAPAT 514 + + P E P EPA + P+ P P+P K++P T PA Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPA----PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303 Query: 515 ASP----PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLP 570 +P PTT P + T P++ P +P P T P+ P P Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361 Query: 571 PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTL-SVR 629 PAPT P+ P T PS +P P+ + + + + P P T S Sbjct: 362 KEPAPTTPKEPAPTTTKEPS---------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412 Query: 630 VSPPQP 635 +P +P Sbjct: 413 TTPKEP 418 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 81.6 bits (200), Expect = 3e-15 Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 31/256 (12%) Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPF 437 P++P P P P P P K P P P P P P +E +P+ P Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414 Query: 438 PTVP--PAPGVSPLPAPAAFPPTPQSVPSPAPTPF------PIELLPLGYSEPA----FG 485 PT P+P PAP P + PAPT P E P EPA Sbjct: 415 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 474 Query: 486 PCFSMPRG------KPPAPSPRGQKASPPTLAPATASP----PTTAGSNNPCLTQLLTAA 535 P + P+ K PAP+ + A T PA +P PTT P + LT Sbjct: 475 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 534 Query: 536 KPEQAL----EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591 PE+ E P ++ +P +P+E P P P TP P P PA P Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 594 Query: 592 PLLVPKAERLSPPAPS 607 P E PAP+ Sbjct: 595 PAPTTPKE----PAPT 606 Score = 81.6 bits (200), Expect = 3e-15 Identities = 101/361 (27%), Positives = 131/361 (36%), Gaps = 47/361 (13%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVP-------PASSAMTHLSGHSRLQARNS 361 P+ P P+ EP +P + + P P P A T + + Sbjct: 456 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515 Query: 362 CPGPLDSSAFLSSDFLLPEDPK------PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPF 415 P +A + L P P+ P P P P L P P P P Sbjct: 516 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 575 Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVP--PAPGVSPLPAPAAFPPT-PQSVPSPAPT---- 468 P A P + P +P+ P PT P PAP AP T P ++ PAPT Sbjct: 576 PKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 634 Query: 469 PFPIELLPLGYSEPAFGPCF----SMPRGKPPA----PSPRGQKASPPTLAPATASPPTT 520 P P EL P EP C + P+G P P+P K PT TA PTT Sbjct: 635 PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA--PTT 692 Query: 521 AGSNNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTP---A 574 P T A E A + P +++ +P +P+ET P P P TP A Sbjct: 693 L--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 750 Query: 575 PTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634 PT P PP P T S P + P S + +LS+ P P L SP + Sbjct: 751 PTTPETPP-PTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKAL--ENSPKE 802 Query: 635 P 635 P Sbjct: 803 P 803 Score = 75.5 bits (184), Expect = 2e-13 Identities = 72/284 (25%), Positives = 97/284 (34%), Gaps = 28/284 (9%) Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFP 438 P++P P P P + P K P P P P +E +P+ P P Sbjct: 262 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 321 Query: 439 TV--PPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKP 495 T PAP + P P + PAPT P E P EP P P K Sbjct: 322 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKE 380 Query: 496 PA------PSPRGQKASPPTL----APATASPPTTAGSNNPCLT------QLLTAAKPEQ 539 PA P+P K PT AP T P + P T T + P Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 440 Query: 540 ALEP-PLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP-------PGPATLAPSR 591 EP P + + +P P T + P P PAPT P+ P P P T Sbjct: 441 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 500 Query: 592 PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 P K +P P+ + + + + T +++P P Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 544 Score = 74.3 bits (181), Expect = 4e-13 Identities = 65/222 (29%), Positives = 80/222 (36%), Gaps = 14/222 (6%) Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT 439 ++P P P P P P K P P P P +E +P+ P PT Sbjct: 419 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 478 Query: 440 VP--PAPGVSPLPAPAA-FPPTPQSVPSPAPTPFPIELLPLGYSEPA------FGPCFSM 490 P PAP PAP P P + PAPT P E P E A P + Sbjct: 479 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT-PKEPAPTTPKETAPTTPKKLTP--TT 535 Query: 491 PRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTL 550 P P + +P LAP T PT P T AA P EP ++ Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPA-PTTPK 593 Query: 551 LRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592 +P +P+E P P P TP T P PA P +P Sbjct: 594 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 635 Score = 69.7 bits (169), Expect = 1e-11 Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 37/345 (10%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQ-----ARNSCP 363 P+ P P+ EP +P + ++ P P + T S + + S P Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453 Query: 364 GPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP-----PPPFPPM 418 + ++ P PK P P P PA EP P P P P Sbjct: 454 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 513 Query: 419 APPTALLQEEPLFSPRFPFPTVPP--APGVSPLPAPAA---------FPPTPQSVPSPAP 467 P +E +P+ PT P AP PAP PTP + PAP Sbjct: 514 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 573 Query: 468 TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTL----APATASPPTTAGS 523 T P P EPA P P+P K + PT AP T P Sbjct: 574 TT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 632 Query: 524 NNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580 P +L E + P ++ +P +P+E P P P TP T P Sbjct: 633 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 692 Query: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGT 625 PA P +P PK L+P G + S P P T Sbjct: 693 LKEPAPTTPKKP--APK--ELAPTTTKGP----TSTTSDKPAPTT 729 Score = 58.9 bits (141), Expect = 2e-08 Identities = 67/217 (30%), Positives = 78/217 (35%), Gaps = 43/217 (19%) Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPC--PPPPFPPMAPPTALLQEEPLFSPRFPF 437 ++P P P P P L P K P C P P P PT + P +P+ P Sbjct: 625 KEPAPTTPKKPAPKELA--PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT-TPKEPA 681 Query: 438 PTVP----------PAPGVSPLPAPAAFPPTPQSVPS------PAPTPFPIELLPLGYSE 481 PT P PAP PAP PT P+ PAPT P E P E Sbjct: 682 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKE 740 Query: 482 PAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQAL 541 PA P P P + S PT T PTT + T L+A +AL Sbjct: 741 PAPTTPKKPAPTTPETPPPTTSEVSTPT----TTKEPTTIHKSPDESTPELSAEPTPKAL 796 Query: 542 EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578 E SP+E P P T TPA T P Sbjct: 797 E------------NSPKE--PGVPTT---KTPAATKP 816 Score = 58.5 bits (140), Expect = 2e-08 Identities = 60/246 (24%), Positives = 90/246 (36%), Gaps = 26/246 (10%) Query: 400 PPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTP 459 P +KV +P P P +E +P+ P T P P + + + P P Sbjct: 230 PTSKVLA-KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288 Query: 460 QSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPA----PSPRGQKASPPT-LAPAT 514 + + P E P EPA + P+ P P+P K++P T PA Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPA----PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344 Query: 515 ASP----PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLP 570 +P PTT P + T P++ P +P P T P+ P P Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTP 402 Query: 571 PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTL-SVR 629 PAPT P+ P T PS +P P+ + + + + P P T S Sbjct: 403 KEPAPTTPKEPAPTTTKEPS---------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453 Query: 630 VSPPQP 635 +P +P Sbjct: 454 TTPKEP 459 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 81.6 bits (200), Expect = 3e-15 Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 31/256 (12%) Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPF 437 P++P P P P P P K P P P P P P +E +P+ P Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466 Query: 438 PTVP--PAPGVSPLPAPAAFPPTPQSVPSPAPTPF------PIELLPLGYSEPA----FG 485 PT P+P PAP P + PAPT P E P EPA Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526 Query: 486 PCFSMPRG------KPPAPSPRGQKASPPTLAPATASP----PTTAGSNNPCLTQLLTAA 535 P + P+ K PAP+ + A T PA +P PTT P + LT Sbjct: 527 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 586 Query: 536 KPEQAL----EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591 PE+ E P ++ +P +P+E P P P TP P P PA P Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 646 Query: 592 PLLVPKAERLSPPAPS 607 P E PAP+ Sbjct: 647 PAPTTPKE----PAPT 658 Score = 81.6 bits (200), Expect = 3e-15 Identities = 101/361 (27%), Positives = 131/361 (36%), Gaps = 47/361 (13%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVP-------PASSAMTHLSGHSRLQARNS 361 P+ P P+ EP +P + + P P P A T + + Sbjct: 508 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567 Query: 362 CPGPLDSSAFLSSDFLLPEDPK------PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPF 415 P +A + L P P+ P P P P L P P P P Sbjct: 568 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 627 Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVP--PAPGVSPLPAPAAFPPT-PQSVPSPAPT---- 468 P A P + P +P+ P PT P PAP AP T P ++ PAPT Sbjct: 628 PKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 686 Query: 469 PFPIELLPLGYSEPAFGPCF----SMPRGKPPA----PSPRGQKASPPTLAPATASPPTT 520 P P EL P EP C + P+G P P+P K PT TA PTT Sbjct: 687 PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA--PTT 744 Query: 521 AGSNNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTP---A 574 P T A E A + P +++ +P +P+ET P P P TP A Sbjct: 745 L--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 802 Query: 575 PTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634 PT P PP P T S P + P S + +LS+ P P L SP + Sbjct: 803 PTTPETPP-PTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKAL--ENSPKE 854 Query: 635 P 635 P Sbjct: 855 P 855 Score = 75.5 bits (184), Expect = 2e-13 Identities = 72/284 (25%), Positives = 97/284 (34%), Gaps = 28/284 (9%) Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFP 438 P++P P P P + P K P P P P +E +P+ P P Sbjct: 314 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 373 Query: 439 TV--PPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKP 495 T PAP + P P + PAPT P E P EP P P K Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKE 432 Query: 496 PA------PSPRGQKASPPTL----APATASPPTTAGSNNPCLT------QLLTAAKPEQ 539 PA P+P K PT AP T P + P T T + P Sbjct: 433 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 492 Query: 540 ALEP-PLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP-------PGPATLAPSR 591 EP P + + +P P T + P P PAPT P+ P P P T Sbjct: 493 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 552 Query: 592 PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 P K +P P+ + + + + T +++P P Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 596 Score = 74.3 bits (181), Expect = 4e-13 Identities = 65/222 (29%), Positives = 80/222 (36%), Gaps = 14/222 (6%) Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT 439 ++P P P P P P K P P P P +E +P+ P PT Sbjct: 471 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 530 Query: 440 VP--PAPGVSPLPAPAA-FPPTPQSVPSPAPTPFPIELLPLGYSEPA------FGPCFSM 490 P PAP PAP P P + PAPT P E P E A P + Sbjct: 531 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT-PKEPAPTTPKETAPTTPKKLTP--TT 587 Query: 491 PRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTL 550 P P + +P LAP T PT P T AA P EP ++ Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPA-PTTPK 645 Query: 551 LRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592 +P +P+E P P P TP T P PA P +P Sbjct: 646 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 687 Score = 69.7 bits (169), Expect = 1e-11 Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 37/345 (10%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQ-----ARNSCP 363 P+ P P+ EP +P + ++ P P + T S + + S P Sbjct: 446 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 505 Query: 364 GPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP-----PPPFPPM 418 + ++ P PK P P P PA EP P P P P Sbjct: 506 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 565 Query: 419 APPTALLQEEPLFSPRFPFPTVPP--APGVSPLPAPAA---------FPPTPQSVPSPAP 467 P +E +P+ PT P AP PAP PTP + PAP Sbjct: 566 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 625 Query: 468 TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTL----APATASPPTTAGS 523 T P P EPA P P+P K + PT AP T P Sbjct: 626 TT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 684 Query: 524 NNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580 P +L E + P ++ +P +P+E P P P TP T P Sbjct: 685 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 744 Query: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGT 625 PA P +P PK L+P G + S P P T Sbjct: 745 LKEPAPTTPKKP--APK--ELAPTTTKGP----TSTTSDKPAPTT 781 Score = 58.9 bits (141), Expect = 2e-08 Identities = 67/217 (30%), Positives = 78/217 (35%), Gaps = 43/217 (19%) Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPC--PPPPFPPMAPPTALLQEEPLFSPRFPF 437 ++P P P P P L P K P C P P P PT + P +P+ P Sbjct: 677 KEPAPTTPKKPAPKELA--PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT-TPKEPA 733 Query: 438 PTVP----------PAPGVSPLPAPAAFPPTPQSVPS------PAPTPFPIELLPLGYSE 481 PT P PAP PAP PT P+ PAPT P E P E Sbjct: 734 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKE 792 Query: 482 PAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQAL 541 PA P P P + S PT T PTT + T L+A +AL Sbjct: 793 PAPTTPKKPAPTTPETPPPTTSEVSTPT----TTKEPTTIHKSPDESTPELSAEPTPKAL 848 Query: 542 EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578 E SP+E P P T TPA T P Sbjct: 849 E------------NSPKE--PGVPTT---KTPAATKP 868 Score = 58.5 bits (140), Expect = 2e-08 Identities = 60/246 (24%), Positives = 90/246 (36%), Gaps = 26/246 (10%) Query: 400 PPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTP 459 P +KV +P P P +E +P+ P T P P + + + P P Sbjct: 282 PTSKVLA-KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340 Query: 460 QSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPA----PSPRGQKASPPT-LAPAT 514 + + P E P EPA + P+ P P+P K++P T PA Sbjct: 341 APTTTKSAPTTPKEPAPTTTKEPA----PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396 Query: 515 ASP----PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLP 570 +P PTT P + T P++ P +P P T P+ P P Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTP 454 Query: 571 PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTL-SVR 629 PAPT P+ P T PS +P P+ + + + + P P T S Sbjct: 455 KEPAPTTPKEPAPTTTKEPS---------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 505 Query: 630 VSPPQP 635 +P +P Sbjct: 506 TTPKEP 511 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 81.6 bits (200), Expect = 3e-15 Identities = 74/256 (28%), Positives = 94/256 (36%), Gaps = 31/256 (12%) Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPF 437 P++P P P P P P K P P P P P P +E +P+ P Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507 Query: 438 PTVP--PAPGVSPLPAPAAFPPTPQSVPSPAPTPF------PIELLPLGYSEPA----FG 485 PT P+P PAP P + PAPT P E P EPA Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567 Query: 486 PCFSMPRG------KPPAPSPRGQKASPPTLAPATASP----PTTAGSNNPCLTQLLTAA 535 P + P+ K PAP+ + A T PA +P PTT P + LT Sbjct: 568 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 627 Query: 536 KPEQAL----EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591 PE+ E P ++ +P +P+E P P P TP P P PA P Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 687 Query: 592 PLLVPKAERLSPPAPS 607 P E PAP+ Sbjct: 688 PAPTTPKE----PAPT 699 Score = 81.6 bits (200), Expect = 3e-15 Identities = 101/361 (27%), Positives = 131/361 (36%), Gaps = 47/361 (13%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVP-------PASSAMTHLSGHSRLQARNS 361 P+ P P+ EP +P + + P P P A T + + Sbjct: 549 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608 Query: 362 CPGPLDSSAFLSSDFLLPEDPK------PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPF 415 P +A + L P P+ P P P P L P P P P Sbjct: 609 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT 668 Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVP--PAPGVSPLPAPAAFPPT-PQSVPSPAPT---- 468 P A P + P +P+ P PT P PAP AP T P ++ PAPT Sbjct: 669 PKAAAPNTPKEPAPT-TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 727 Query: 469 PFPIELLPLGYSEPAFGPCF----SMPRGKPPA----PSPRGQKASPPTLAPATASPPTT 520 P P EL P EP C + P+G P P+P K PT TA PTT Sbjct: 728 PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA--PTT 785 Query: 521 AGSNNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTP---A 574 P T A E A + P +++ +P +P+ET P P P TP A Sbjct: 786 L--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 843 Query: 575 PTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQ 634 PT P PP P T S P + P S + +LS+ P P L SP + Sbjct: 844 PTTPETPP-PTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKAL--ENSPKE 895 Query: 635 P 635 P Sbjct: 896 P 896 Score = 75.5 bits (184), Expect = 2e-13 Identities = 72/284 (25%), Positives = 97/284 (34%), Gaps = 28/284 (9%) Query: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFP 438 P++P P P P + P K P P P P +E +P+ P P Sbjct: 355 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 414 Query: 439 TV--PPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPA-FGPCFSMPRGKP 495 T PAP + P P + PAPT P E P EP P P K Sbjct: 415 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTPTTPKEPAPTTKE 473 Query: 496 PA------PSPRGQKASPPTL----APATASPPTTAGSNNPCLT------QLLTAAKPEQ 539 PA P+P K PT AP T P + P T T + P Sbjct: 474 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 533 Query: 540 ALEP-PLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP-------PGPATLAPSR 591 EP P + + +P P T + P P PAPT P+ P P P T Sbjct: 534 TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 593 Query: 592 PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 P K +P P+ + + + + T +++P P Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 637 Score = 74.3 bits (181), Expect = 4e-13 Identities = 65/222 (29%), Positives = 80/222 (36%), Gaps = 14/222 (6%) Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPT 439 ++P P P P P P K P P P P +E +P+ P PT Sbjct: 512 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 571 Query: 440 VP--PAPGVSPLPAPAA-FPPTPQSVPSPAPTPFPIELLPLGYSEPA------FGPCFSM 490 P PAP PAP P P + PAPT P E P E A P + Sbjct: 572 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT-PKEPAPTTPKETAPTTPKKLTP--TT 628 Query: 491 PRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTL 550 P P + +P LAP T PT P T AA P EP ++ Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA-PNTPKEPA-PTTPK 686 Query: 551 LRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRP 592 +P +P+E P P P TP T P PA P +P Sbjct: 687 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 728 Score = 69.7 bits (169), Expect = 1e-11 Identities = 86/345 (24%), Positives = 114/345 (33%), Gaps = 37/345 (10%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQ-----ARNSCP 363 P+ P P+ EP +P + ++ P P + T S + + S P Sbjct: 487 PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 546 Query: 364 GPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP-----PPPFPPM 418 + ++ P PK P P P PA EP P P P P Sbjct: 547 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 606 Query: 419 APPTALLQEEPLFSPRFPFPTVPP--APGVSPLPAPAA---------FPPTPQSVPSPAP 467 P +E +P+ PT P AP PAP PTP + PAP Sbjct: 607 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 666 Query: 468 TPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTL----APATASPPTTAGS 523 T P P EPA P P+P K + PT AP T P Sbjct: 667 TT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 725 Query: 524 NNPCLTQLLTAAKPEQA---LEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580 P +L E + P ++ +P +P+E P P P TP T P Sbjct: 726 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 785 Query: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGT 625 PA P +P PK L+P G + S P P T Sbjct: 786 LKEPAPTTPKKP--APK--ELAPTTTKGP----TSTTSDKPAPTT 822 Score = 58.9 bits (141), Expect = 2e-08 Identities = 67/217 (30%), Positives = 78/217 (35%), Gaps = 43/217 (19%) Query: 380 EDPKPRLPPPPVPPPLLHYPPPAKVPGLEPC--PPPPFPPMAPPTALLQEEPLFSPRFPF 437 ++P P P P P L P K P C P P P PT + P +P+ P Sbjct: 718 KEPAPTTPKKPAPKELA--PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT-TPKEPA 774 Query: 438 PTVP----------PAPGVSPLPAPAAFPPTPQSVPS------PAPTPFPIELLPLGYSE 481 PT P PAP PAP PT P+ PAPT P E P E Sbjct: 775 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKE 833 Query: 482 PAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQAL 541 PA P P P + S PT T PTT + T L+A +AL Sbjct: 834 PAPTTPKKPAPTTPETPPPTTSEVSTPT----TTKEPTTIHKSPDESTPELSAEPTPKAL 889 Query: 542 EPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP 578 E SP+E P P T TPA T P Sbjct: 890 E------------NSPKE--PGVPTT---KTPAATKP 909 Score = 58.5 bits (140), Expect = 2e-08 Identities = 60/246 (24%), Positives = 90/246 (36%), Gaps = 26/246 (10%) Query: 400 PPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTP 459 P +KV +P P P +E +P+ P T P P + + + P P Sbjct: 323 PTSKVLA-KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381 Query: 460 QSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPA----PSPRGQKASPPT-LAPAT 514 + + P E P EPA + P+ P P+P K++P T PA Sbjct: 382 APTTTKSAPTTPKEPAPTTTKEPA----PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437 Query: 515 ASP----PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLP 570 +P PTT P + T P++ P +P P T P+ P P Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKE--PAPTTKEPAPTTPKEPAPTAPKKPAPTTP 495 Query: 571 PTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTL-SVR 629 PAPT P+ P T PS +P P+ + + + + P P T S Sbjct: 496 KEPAPTTPKEPAPTTTKEPS---------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 546 Query: 630 VSPPQP 635 +P +P Sbjct: 547 TTPKEP 552 >gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] Length = 1003 Score = 80.5 bits (197), Expect = 6e-15 Identities = 103/350 (29%), Positives = 129/350 (36%), Gaps = 62/350 (17%) Query: 312 PMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRL-QARNSCPGPLDSSA 370 P P + P P G+L PE P S A L+G L R + P P S Sbjct: 140 PGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGS- 198 Query: 371 FLSSDFLLPEDPKPRLPPPPVPPPLLHYPP--------PAKVPGLEPCPPPPFPPMAPPT 422 SS LP P PPP P L+ P + VP PP P +PP+ Sbjct: 199 --SSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPS 256 Query: 423 ALLQEEPLF--SPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYS 480 + PLF S P +PP+ + P PA+ PP S A P+ L PLG + Sbjct: 257 ----DPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPV-----SSATMHLPLVLGPLGGA 307 Query: 481 EPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQA 540 GP G PP + A+ P P T G + +A Sbjct: 308 PTVEGP------GAPPFLASSLLSAAAKAQHPPLPPPSTLQG-------------RRPRA 348 Query: 541 LEPPLVSSTLLRSPGSPQETVPEFPCTFL-------PPTP---APTPPRPPPGPATL-AP 589 P S+ LR P + P P T P TP P P P P P +L P Sbjct: 349 QAPSASHSSSLR----PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEP 404 Query: 590 SRPLLVPKAERLSPPAPSGSER----RLSGDLSSMPGPGTLSVRVSPPQP 635 S+P+L L P P S L G + +P P TLS SPPQP Sbjct: 405 SQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLS-SGSPPQP 453 Score = 72.8 bits (177), Expect = 1e-12 Identities = 120/409 (29%), Positives = 149/409 (36%), Gaps = 105/409 (25%) Query: 307 RLPQP-PMPSNFPEPPS-FSPVVDSLFSSGTLGPE--------------VPPASSAMTHL 350 R P P P P + PEP P V SL T GP +PP + + Sbjct: 390 RAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGS 449 Query: 351 SGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPP--PPVPPPLLHYPPPAKVPGLE 408 R + S PG S LSS +P P P P VP P+L P++ G+ Sbjct: 450 PPQPRHPIQPSLPGTTSGS--LSS---VPGAPAPPAASKAPVVPSPVLQ--SPSEGLGMG 502 Query: 409 PCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFP------PTPQSV 462 P P PP+A A FPFP+ P G++ + A FP P P S+ Sbjct: 503 AGPACPLPPLAGGEA-----------FPFPS--PEQGLAL--SGAGFPGMLGALPLPLSL 547 Query: 463 PSPAPTPF-----------------PIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKA 505 P P+P P LLP P GP + G+P PS Sbjct: 548 GQPPPSPLLNHSLFGVLTGGGGQPPPEPLLP-----PPGGPGPPLAPGEPEGPSLLVASL 602 Query: 506 SPPT----LAPATASPPTTAGSNNPCLTQLLTAAKPEQALE-------PPLVS----STL 550 PP L P +A P S P L TA E + E P S L Sbjct: 603 LPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPL 662 Query: 551 LRSPGSPQETVPEFPCTFLPPT---PAPTPPRP------PPGPATLAPSRPLLVPKAERL 601 L P S T+ L T P+ TPP+P PGP T + + P A L Sbjct: 663 LFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSL 722 Query: 602 SPPAPSGSER-----------RLSGDLSSMPG-PGTLSVRVSPPQPILS 638 APS S R L GDLSS+ PG L + PP P+LS Sbjct: 723 GK-APSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLS 770 Score = 67.8 bits (164), Expect = 4e-11 Identities = 113/401 (28%), Positives = 146/401 (36%), Gaps = 75/401 (18%) Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQ-------PSLDDFMDISDFFTNSRLPQPPMPSN 316 PSP+ P + A P L PL PS + + +S L P+P + Sbjct: 488 PSPVLQSPSEGLGMGAGPACP-LPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLS 546 Query: 317 FPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDF 376 +PP + SLF T G PP + G A GP S ++S Sbjct: 547 LGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGP---SLLVAS-- 601 Query: 377 LLPEDPKPRLPPPPVPP--------PLLHYPPPA----------------KVPGLEPCPP 412 LLP P LPPP PP PLL P A GL P Sbjct: 602 LLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSP 661 Query: 413 PPFPPM-APPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 FPP+ APPT + L + + L P+ PP P + +P P P P Sbjct: 662 LLFPPLSAPPTLIALNSALLA--------------ATLDPPSGTPPQPCVLSAPQPGP-P 706 Query: 472 IELLPLGYSEPAFGPCFSMP--RGKPP-APSPRGQKASPPTLAPATASP---PTTAGSNN 525 + ++P P G+PP SP + L+ T+SP P+ Sbjct: 707 TSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPG 766 Query: 526 PCLT-QLLTAAKPEQALEPPLVSST-----LLRSPGSPQETVPEFPCTFLPP-TPA---- 574 P L+ QL P PPL ++ LL+S P E PE PC LPP +PA Sbjct: 767 PLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQ-PEAPC--LPPESPASALE 823 Query: 575 PTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSG 615 P P RPP + LAP P L SG R G Sbjct: 824 PEPARPP--LSALAPPHGSPDPPVPELLTGRGSGKRGRRGG 862 Score = 67.4 bits (163), Expect = 5e-11 Identities = 125/491 (25%), Positives = 169/491 (34%), Gaps = 83/491 (16%) Query: 193 RKPSREDDLLAPKQAEGRWPPPEQWCKQLFSSVV------PVLLGDPEEEPGGRQLLDLN 246 R P R G PP Q F ++ P L DP G Sbjct: 146 RPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGS------- 198 Query: 247 CFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNS 306 S F + PSP PP P ++ PS + + S Sbjct: 199 ------SSPRFLPRGNAPSPAPPPP------------PAISLNAPSYNWGAALRSSLVPS 240 Query: 307 RLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCP--- 363 L PP P PPS P+ S P +PP+++ H S+ ++ Sbjct: 241 DLGSPPAPHASSSPPSDPPLFHC--SDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLP 298 Query: 364 ---GPLDSSA---------FLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCP 411 GPL + FL+S LL K + PP P P L P A+ P Sbjct: 299 LVLGPLGGAPTVEGPGAPPFLASS-LLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSS 357 Query: 412 ---PPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFP-PTPQSVPSPA- 466 P P PPT E P+ P + P AP +P+P P + P P+ +PS Sbjct: 358 SLRPSQRRPRRPPTVFRLLEGR-GPQTPRRSRPRAP--APVPQPFSLPEPSQPILPSVLS 414 Query: 467 ----PTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAG 522 PTP P +S+ +F S PP P SPP P P+ G Sbjct: 415 LLGLPTPGP------SHSDGSFNLLGSDAHLPPP---PTLSSGSPPQ--PRHPIQPSLPG 463 Query: 523 SNNPCLTQLLTAAKPEQALEPPLVSSTLLRSP--GSPQETVPEFPCTFLPPTPAPTPPRP 580 + + L+ + A P A + P+V S +L+SP G P P L A P P Sbjct: 464 TTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSP 523 Query: 581 PPGPATLAPSRP-----LLVPKAERLSPPAPSGSERRLSGDLS---SMPGPGTLSVRVSP 632 G A P L +P + PP+P L G L+ P P L Sbjct: 524 EQGLALSGAGFPGMLGALPLPLSLGQPPPSPL-LNHSLFGVLTGGGGQPPPEPLLPPPGG 582 Query: 633 PQPILSRGRPD 643 P P L+ G P+ Sbjct: 583 PGPPLAPGEPE 593 >gi|62000702 diacylglycerol kinase kappa [Homo sapiens] Length = 1271 Score = 80.1 bits (196), Expect = 8e-15 Identities = 70/213 (32%), Positives = 80/213 (37%), Gaps = 40/213 (18%) Query: 399 PPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAA---- 454 P + P P PPPP+PP PP A PL S P P P P ++P P P A Sbjct: 14 PQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSES 73 Query: 455 -----FPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP---PAPSPRGQKAS 506 PTP+ PA P P EPA P P +P PAP P + A Sbjct: 74 ATELYTEPTPEPATEPASEPAP---------EPATEPA-PEPATEPAPEPAPEPATESAP 123 Query: 507 PPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEF-- 564 PT PA S P A +L PE A EP T L +P E PEF Sbjct: 124 EPTPEPALESVPEPA-------PELTPEVAPELAPEPTPEPVTEL-APEFCPEAAPEFRP 175 Query: 565 ---PCTFLPPTPA-----PTPPRPPPGPATLAP 589 PC P T P P P P+ P Sbjct: 176 SPAPCLLQCPVDTRERGLKTSPSPSPSPSPRTP 208 Score = 71.2 bits (173), Expect = 4e-12 Identities = 70/213 (32%), Positives = 86/213 (40%), Gaps = 39/213 (18%) Query: 379 PEDPKPRLPPPPVP-----PPLLHYPPPAKVPGLEPCP---PPPFPPMAPPTALLQEEPL 430 PE P P PPPP P PPLL P +P EPCP P P P +A L Sbjct: 24 PEPPPPWPPPPPPPAPPPAPPLLSEASPEPIP--EPCPELAPGPCPEATSESA----TEL 77 Query: 431 FSPRFPFPTVPPAPGVSPLPAPAAFP-PTPQSVPSPAPTPFP-IELLPLGYSEPAFGPCF 488 ++ P P PA P P PA P P P + P+P P P P E P EPA Sbjct: 78 YTEPTPEPATEPAS--EPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPAL---- 131 Query: 489 SMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALE-PPLVS 547 P P+P P LAP P +T+L PE A E P + Sbjct: 132 ----ESVPEPAPELTPEVAPELAPEPTPEP---------VTELAPEFCPEAAPEFRPSPA 178 Query: 548 STLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580 LL+ P +E + T P+P+P+P P Sbjct: 179 PCLLQCPVDTRERGLK---TSPSPSPSPSPRTP 208 Score = 64.7 bits (156), Expect = 3e-10 Identities = 63/177 (35%), Positives = 74/177 (41%), Gaps = 17/177 (9%) Query: 439 TVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAP 498 T PP G P +P PP P P PAP P P LL EP PC + G P P Sbjct: 11 TAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAP-PLLSEASPEPIPEPCPELAPG--PCP 67 Query: 499 SPRGQKA----SPPTLAPAT--ASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLR 552 + A + PT PAT AS P + P + T PE A E P S Sbjct: 68 EATSESATELYTEPTPEPATEPASEPAPEPATEPA-PEPATEPAPEPAPE-PATESAPEP 125 Query: 553 SPGSPQETVPEFPCTFLPPTPAP-TPPRPPPGPAT-LAPSRPLLVPKAERLSPPAPS 607 +P E+VPE P L P AP P P P P T LAP P+A P+P+ Sbjct: 126 TPEPALESVPE-PAPELTPEVAPELAPEPTPEPVTELAPE---FCPEAAPEFRPSPA 178 Score = 58.5 bits (140), Expect = 2e-08 Identities = 64/212 (30%), Positives = 78/212 (36%), Gaps = 30/212 (14%) Query: 309 PQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDS 368 P+PP P P PP P L S + P P A CP Sbjct: 24 PEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPEL-----------APGPCPEATSE 72 Query: 369 SAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEE 428 SA ++ P+P P P P PA P EP P P P E Sbjct: 73 SA---TELYTEPTPEPATEPASEPA-----PEPATEPAPEPATEPAPEPAPEPATESAPE 124 Query: 429 PLFSPRFPFPTVP-PAPGVSPLPAPAAFP-PTPQSVPSPAPTPFPIELLPLGYSEPAFGP 486 P +P +VP PAP ++P AP P PTP+ V AP P E P PA P Sbjct: 125 P--TPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCP-EAAPEFRPSPA--P 179 Query: 487 CFSMPRGKPPAPSPRGQKASP-PTLAPATASP 517 C P RG K SP P+ +P+ +P Sbjct: 180 CLLQ---CPVDTRERGLKTSPSPSPSPSPRTP 208 Score = 33.1 bits (74), Expect = 1.1 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 5/68 (7%) Query: 570 PPTPAPTPPRPPPGPATLAPSRPLLVPK-AERLSP-PAPSGSERRLSGDLSSMPGPGTLS 627 PP P P P PPP P L+ + P +P+ L+P P P + + +L + P P + Sbjct: 31 PPPPPP--PAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSESAT-ELYTEPTPEPAT 87 Query: 628 VRVSPPQP 635 S P P Sbjct: 88 EPASEPAP 95 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 79.7 bits (195), Expect = 1e-14 Identities = 70/250 (28%), Positives = 89/250 (35%), Gaps = 40/250 (16%) Query: 266 PLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSP 325 P L ++ +G + + P P D S F+ LP PP ++P Sbjct: 225 PPTLVYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYP------- 277 Query: 326 VVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPR 385 VD+ SG GP+ S++ S S PGP A P Sbjct: 278 -VDNQRGSGLAGPK----RSSVVSPSHPPPAPPLGSPPGPKPGFA-------------PP 319 Query: 386 LPPPPVPPPLLHYPPPAKVPGLEP--CPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPA 443 PPP PPP++ PPP G PPPP PP PP P F P PP Sbjct: 320 PAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPP----------HPDFAAPPPPPP 369 Query: 444 PGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQ 503 P + P PP P S P+ P P P G P F P PP Sbjct: 370 PPAADYPT---LPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKP 426 Query: 504 KASPPTLAPA 513 K+S P ++ A Sbjct: 427 KSSLPAVSDA 436 Score = 75.1 bits (183), Expect = 2e-13 Identities = 73/258 (28%), Positives = 87/258 (33%), Gaps = 82/258 (31%) Query: 360 NSCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPP----------PAKVPGLEP 409 +S P P S + S ED LPPPP YP P + + P Sbjct: 244 SSYPPPPQSDSASSPSPSFSED---NLPPPPAE---FSYPVDNQRGSGLAGPKRSSVVSP 297 Query: 410 CPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTP 469 PPP PP+ P P PG +P PAP PP +P P P Sbjct: 298 SHPPPAPPLGSPPG------------------PKPGFAPPPAPPPPPPPMIGIPPPPP-- 337 Query: 470 FPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLT 529 P+G+ P G PP PSP P AP PP A + P L Sbjct: 338 ------PVGFGSP----------GTPPPPSPPSFPPHPDFAAPPPPPPPPAA--DYPTLP 379 Query: 530 QLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAP 589 PPL T G+P PP P P PP PPP P T A Sbjct: 380 P------------PPLSQPT----GGAP------------PPPPPPPPPGPPPPPFTGAD 411 Query: 590 SRPLLVPKAERLSPPAPS 607 +P + P + P S Sbjct: 412 GQPAIPPPLSDTTKPKSS 429 Score = 45.4 bits (106), Expect = 2e-04 Identities = 68/261 (26%), Positives = 83/261 (31%), Gaps = 75/261 (28%) Query: 381 DPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTV 440 + K +L PP L++ + +E +PP PP + P SP F + Sbjct: 214 ESKEKLGTSGYPPTLVYQN--GSIGCVENVDASSYPP--PPQSDSASSP--SPSFSEDNL 267 Query: 441 PPAPGVSPLPAP-----AAFPPTPQSVPSPA-PTPFPIELLPLGYSEPAFGPCFSMPRGK 494 PP P P P SV SP+ P P P PLG S P P F+ P Sbjct: 268 PPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAP----PLG-SPPGPKPGFAPPPAP 322 Query: 495 PPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSP 554 PP P P PP PP GS P Sbjct: 323 PPPPPPMIGIPPPP--------PPVGFGS------------------------------P 344 Query: 555 GSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLS 614 G+P P P+PP PP P AP P P A+ + P P LS Sbjct: 345 GTP---------------PPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPP-----LS 384 Query: 615 GDLSSMPGPGTLSVRVSPPQP 635 P P PP P Sbjct: 385 QPTGGAPPPPPPPPPPGPPPP 405 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 79.3 bits (194), Expect = 1e-14 Identities = 75/241 (31%), Positives = 89/241 (36%), Gaps = 15/241 (6%) Query: 374 SDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSP 433 SD + + PP VPP + PP P L P P PP P PPT L P +P Sbjct: 380 SDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAP 439 Query: 434 RFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRG 493 PF P PG+ P P PP P P P P P LP G P GP +P Sbjct: 440 --PFLRPPGMPGLRG-PLPRLLPPGPPPGRPPGPPPGPPPGLPPG--PPPRGPPPRLPPP 494 Query: 494 KPPA-PSPRGQKASPPTLAPATASPP---TTAGSNNPCL----TQLLTAAKPEQALEPPL 545 PP P PR PP + P +PP A NP + L+ K + + Sbjct: 495 APPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATI 554 Query: 546 VSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPA 605 PQ T P+ T PT R AT AP R A L+ A Sbjct: 555 EKKATATISAKPQITNPKAEITRFVPTALRV--RRENKGATAAPQRKSEDDSAVPLAKAA 612 Query: 606 P 606 P Sbjct: 613 P 613 Score = 60.8 bits (146), Expect = 5e-09 Identities = 51/166 (30%), Positives = 59/166 (35%), Gaps = 34/166 (20%) Query: 306 SRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGP 365 S++ PPMP P P +P + L P PP + G L+ GP Sbjct: 400 SQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLR------GP 453 Query: 366 LDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALL 425 L PRL PP PP PPP PGL P PPP PP Sbjct: 454 L-----------------PRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPP-------- 488 Query: 426 QEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFP 471 P P P PP PG+ P P P + PAP P P Sbjct: 489 ---PRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNP 531 Score = 53.9 bits (128), Expect = 6e-07 Identities = 50/149 (33%), Positives = 56/149 (37%), Gaps = 12/149 (8%) Query: 495 PPAPSPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSP 554 PP P Q +PP P PP P L P A PP LR P Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGA--PPF-----LRPP 445 Query: 555 GSPQETVPEFPCTFLPPTPAP-TPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRL 613 G P P P LPP P P PP PPPGP P P RL PPAP G Sbjct: 446 GMPGLRGP-LP-RLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPR 503 Query: 614 SGDLSS--MPGPGTLSVRVSPPQPILSRG 640 G + +P G + PP P+ + G Sbjct: 504 PGMMRPPLVPPLGPAPPGLFPPAPLPNPG 532 Score = 33.5 bits (75), Expect = 0.83 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 17/72 (23%) Query: 365 PLDSSAFLSSDFLLPEDPKPRLPPPPV--------PP-------PLLHYPPPAKVPGLEP 409 PL S+ L+ + P P PP + PP PLL + P PG +P Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199 Query: 410 CPPPPFPPMAPP 421 PPP PP PP Sbjct: 200 PGPPPGPP--PP 209 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 78.6 bits (192), Expect = 2e-14 Identities = 107/389 (27%), Positives = 138/389 (35%), Gaps = 62/389 (15%) Query: 320 PPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLP 379 P S S S G P T + H++L + P A D + Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA----DIVRG 291 Query: 380 EDPKPRLPPPPVPPPLLHYP--PPAKVPGLEPCPPPPFPPMAPPTALLQE--------EP 429 E KP LP P PP P PPA+ PG E P P P A P+ L + +P Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351 Query: 430 LFSPRFPFPTVPPAPGVSPLPAPA-----AFPPTPQSVPSPAPTPFPIELLPLGYSEPAF 484 P P T PPA + P PA P + Q P P + P PA Sbjct: 352 PVQP--PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK 409 Query: 485 GPCFSMPRGKPPAPSPRGQ---KASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAAK 536 P + KP A P Q KA PT P P AG Q Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469 Query: 537 PEQ----ALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP---PGPATLAP 589 P Q A PP + PG P + P+ P + PP+ P +PP PGPA +P Sbjct: 470 PSQLPGPAKPPP-------QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521 Query: 590 SRP-----------LLVPKAERLSPPAPSG--SERRLSGDLSSMP-GPGTL--SVRVSPP 633 +P P A++ SP PS S + +S S P P T+ S + P Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581 Query: 634 QPILSRGRPDSNKNRRITHISAEQKRRFN 662 Q + P N + H+ +K FN Sbjct: 582 QGLPKTICPLCNTTELLLHV--PEKANFN 608 Score = 58.9 bits (141), Expect = 2e-08 Identities = 94/389 (24%), Positives = 138/389 (35%), Gaps = 95/389 (24%) Query: 314 PSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLS 373 PS+ P + + F+SG + PAS + S L A+ P P F S Sbjct: 2344 PSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAK---PRPF----FRS 2396 Query: 374 SDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSP 433 S + P PPPP PPP PPP P PPPP PP+ PPT+ +P P Sbjct: 2397 SSLDISAQP----PPPPPPPP----PPP------PPPPPPPPPPLPPPTS---PKPTILP 2439 Query: 434 RFPFPTVPPAPGVSPL-------------------------PAPAAFPPTPQSVPS---- 464 + P +PL AP PP P S+PS Sbjct: 2440 KKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVF 2499 Query: 465 ---PAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTA 521 P P+ PI P+ P P P P+ +S TL T++ Sbjct: 2500 THRPEPSKPPIAPKPV---IPQLPTTTQKPTDIHPKPTGLSLTSS-MTLNLVTSADYKLP 2555 Query: 522 GSNNPCLTQLLTAAKP--EQALEPPLVSSTLLRSPGSPQETVPEFPCTFLP---PTPAPT 576 +P L+ + P ++L V TL PG+P ++ T P P+ Sbjct: 2556 SPTSP-LSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLV 2614 Query: 577 PPRP-----PPGPATLAP-----------------SRPLLVPKAERLSPPAPSG------ 608 P PP A P + P+ P + + +P + + Sbjct: 2615 SVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEV 2674 Query: 609 SERRLSGDLSSMPGPGTLSVRVS-PPQPI 636 S+ +S S+ P G S+ ++ PP+P+ Sbjct: 2675 SKTEVSATRSTAPSVGLSSISITIPPEPL 2703 Score = 53.1 bits (126), Expect = 1e-06 Identities = 78/299 (26%), Positives = 103/299 (34%), Gaps = 69/299 (23%) Query: 382 PKPRLPPPPVPP-------PLLHYPPPAKVPGLEP-----CPPPPFPPMAPPTALLQEE- 428 P + PP P+P PL P + +P PP P+ PT Q + Sbjct: 210 PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269 Query: 429 ---PL-------------------FSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPA 466 PL P P P+ PP +P PA P +S P PA Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329 Query: 467 PTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNP 526 P P G ++P ++ KPP P K L PA P GS P Sbjct: 330 KPP----AQPSGLTKPLAQQPGTV---KPPVQPPGTTKPPAQPLGPA-KPPAQQTGSEKP 381 Query: 527 CLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP------ 580 Q P+ +PP V T + PG P P T TP P +P Sbjct: 382 SSEQ----PGPKALAQPPGVGKTPAQQPG------PAKPPTQQVGTPKPLAQQPGLQSPA 431 Query: 581 -PPGPATLAPSR---PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 PGP T P + P +P A++ P S + + S +PGP + P QP Sbjct: 432 KAPGP-TKTPVQQPGPGKIP-AQQAGPGKTSAQQTGPTKPPSQLPGP----AKPPPQQP 484 Score = 50.8 bits (120), Expect = 5e-06 Identities = 101/427 (23%), Positives = 140/427 (32%), Gaps = 92/427 (21%) Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSF 323 PSP + P + G QP QP P PS +P + Sbjct: 299 PSPSKPPIQQPTPGKPPAQQPGHEKSQPG--------------PAKPPAQPSGLTKPLAQ 344 Query: 324 SP--VVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPED 381 P V + GT P P A + + PGP + + Sbjct: 345 QPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQ 404 Query: 382 PKPRLPPPP---VPPPLLHYP---PPAKVPGLEPCP-----PPPFP-------------- 416 P P PP P PL P PAK PG P P P Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464 Query: 417 -PMAPPTALL-QEEPLFSPRFPFPTVPP--APGVSPLPA--PAAFPPTPQSVPSPAPTPF 470 P PP+ L +P P+ P P PP PG + P+ P + P PQ P PA Sbjct: 465 GPTKPPSQLPGPAKP--PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAK--- 518 Query: 471 PIELLPLGYSEPAFGPCFSMPRGKPPAPSP--------------RGQKASPPTLAPATAS 516 P P P+ P + P + P+P+ G+ PPT++P+ Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ 578 Query: 517 PPTTAGSNNPC----LTQLLTAAKPEQA-----LEPPLVSSTLLRSPGSPQET-VPEFPC 566 PP+ C T+LL PE+A E +L +P T V E+ C Sbjct: 579 PPSQGLPKTICPLCNTTELLLHV-PEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLC 637 Query: 567 T----------FLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGD 616 L P P+ P+ P T + P+ ++ SP + ++ D Sbjct: 638 LNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ----D 693 Query: 617 LSSMPGP 623 LS P P Sbjct: 694 LSKAPEP 700 Score = 48.5 bits (114), Expect = 3e-05 Identities = 80/358 (22%), Positives = 114/358 (31%), Gaps = 104/358 (29%) Query: 378 LPEDPKPRLPPPPVPPPLLHYPPPAK-------------VPGLEPCPP------------ 412 L + P+P+ PPP V P LH P AK P EP P Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753 Query: 413 PPFPPMAPPTALLQEEPLFSPRFPFP-----------TVPPAPGVSPLPAPAAFPPTPQS 461 P P M PT L + + P T PP S P+ +FPPT + Sbjct: 754 PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS-QSFPPTGEK 812 Query: 462 VPSPAPTPFPIELLPLGYSEPAF----GPCFS---------------------------- 489 V +PF + +P S+ GP Sbjct: 813 V-----SPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867 Query: 490 ---MPRGKPPAPSPR---GQKASPPTLAPATASPPTTAGSNNPCLTQLLTA--AKPEQAL 541 MP+G P P PR GQ P +P N +T + P++ + Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETV 927 Query: 542 EPPLV---------SSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP-----------RPP 581 L +S L+ + G P P + PAP+ P + P Sbjct: 928 TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP 987 Query: 582 PGPATLAP-SRPLLVPKAERLSPPAPSG-SERRLSGDLSSMPGPGTLSVRVSPPQPIL 637 P PA P + P AE+L P A + +R + P + S+ P + +L Sbjct: 988 PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVL 1045 Score = 33.9 bits (76), Expect = 0.64 Identities = 44/182 (24%), Positives = 61/182 (33%), Gaps = 38/182 (20%) Query: 456 PPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPS---PRGQKASPPTLAP 512 PP Q P P P P P G P + S P K+ PP Sbjct: 209 PPLQQQPPKPIPKQ----------QGPGRDPL--QQDGTPKSISSQQPEKIKSQPPGTGK 256 Query: 513 ATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPT 572 P T +++ L A++P+ + ++ S SP + + P PP Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPA 316 Query: 573 PAPTPPRPPPGPATLAPSRPLLVPKAERLSPPA-PSGSERRLSGDLSSMPGPGTLSVRVS 631 P + PGPA PPA PSG + L+ PGT+ V Sbjct: 317 QQPGHEKSQPGPA----------------KPPAQPSGLTKPLAQQ------PGTVKPPVQ 354 Query: 632 PP 633 PP Sbjct: 355 PP 356 Score = 32.0 bits (71), Expect = 2.4 Identities = 32/124 (25%), Positives = 44/124 (35%), Gaps = 12/124 (9%) Query: 478 GYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCL-TQLLTAAK 536 G P P + PP Q PPT SP T ++P L TQ T+ Sbjct: 3852 GIERPRTAPQTEFSQFIPPQTQTESQLV-PPT------SPYTQYQYSSPALPTQAPTSYT 3904 Query: 537 PEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVP 596 + E TL SP +T P F P P P P+ PS+ +++ Sbjct: 3905 QQSHFE----QQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQ 3960 Query: 597 KAER 600 + R Sbjct: 3961 QKPR 3964 Score = 30.0 bits (66), Expect = 9.2 Identities = 34/159 (21%), Positives = 56/159 (35%), Gaps = 25/159 (15%) Query: 354 SRLQARNSCPGPLDSSAFLSSDFLLPE-DPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPP 412 +R+++++ P + S F+ P+ + +L PP P Y PA Sbjct: 3845 TRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPAL--------- 3895 Query: 413 PPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTP--- 469 P PT+ Q+ V P A A TPQ P+P P P Sbjct: 3896 ----PTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQ 3951 Query: 470 FPIELLPLG--------YSEPAFGPCFSMPRGKPPAPSP 500 P +++ + Y EP + + R +P +P Sbjct: 3952 LPSQMMVIQQKPRQTTLYLEPKITSNYEVIRNQPLMIAP 3990 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 78.6 bits (192), Expect = 2e-14 Identities = 107/389 (27%), Positives = 138/389 (35%), Gaps = 62/389 (15%) Query: 320 PPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLP 379 P S S S G P T + H++L + P A D + Sbjct: 236 PKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA----DIVRG 291 Query: 380 EDPKPRLPPPPVPPPLLHYP--PPAKVPGLEPCPPPPFPPMAPPTALLQE--------EP 429 E KP LP P PP P PPA+ PG E P P P A P+ L + +P Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351 Query: 430 LFSPRFPFPTVPPAPGVSPLPAPA-----AFPPTPQSVPSPAPTPFPIELLPLGYSEPAF 484 P P T PPA + P PA P + Q P P + P PA Sbjct: 352 PVQP--PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAK 409 Query: 485 GPCFSMPRGKPPAPSPRGQ---KASPPTLAPATAS-----PPTTAGSNNPCLTQLLTAAK 536 P + KP A P Q KA PT P P AG Q Sbjct: 410 PPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469 Query: 537 PEQ----ALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP---PGPATLAP 589 P Q A PP + PG P + P+ P + PP+ P +PP PGPA +P Sbjct: 470 PSQLPGPAKPPP-------QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521 Query: 590 SRP-----------LLVPKAERLSPPAPSG--SERRLSGDLSSMP-GPGTL--SVRVSPP 633 +P P A++ SP PS S + +S S P P T+ S + P Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581 Query: 634 QPILSRGRPDSNKNRRITHISAEQKRRFN 662 Q + P N + H+ +K FN Sbjct: 582 QGLPKTICPLCNTTELLLHV--PEKANFN 608 Score = 58.9 bits (141), Expect = 2e-08 Identities = 94/389 (24%), Positives = 138/389 (35%), Gaps = 95/389 (24%) Query: 314 PSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLS 373 PS+ P + + F+SG + PAS + S L A+ P P F S Sbjct: 2344 PSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAK---PRPF----FRS 2396 Query: 374 SDFLLPEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSP 433 S + P PPPP PPP PPP P PPPP PP+ PPT+ +P P Sbjct: 2397 SSLDISAQP----PPPPPPPP----PPP------PPPPPPPPPPLPPPTS---PKPTILP 2439 Query: 434 RFPFPTVPPAPGVSPL-------------------------PAPAAFPPTPQSVPS---- 464 + P +PL AP PP P S+PS Sbjct: 2440 KKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVF 2499 Query: 465 ---PAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTA 521 P P+ PI P+ P P P P+ +S TL T++ Sbjct: 2500 THRPEPSKPPIAPKPV---IPQLPTTTQKPTDIHPKPTGLSLTSS-MTLNLVTSADYKLP 2555 Query: 522 GSNNPCLTQLLTAAKP--EQALEPPLVSSTLLRSPGSPQETVPEFPCTFLP---PTPAPT 576 +P L+ + P ++L V TL PG+P ++ T P P+ Sbjct: 2556 SPTSP-LSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLV 2614 Query: 577 PPRP-----PPGPATLAP-----------------SRPLLVPKAERLSPPAPSG------ 608 P PP A P + P+ P + + +P + + Sbjct: 2615 SVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEV 2674 Query: 609 SERRLSGDLSSMPGPGTLSVRVS-PPQPI 636 S+ +S S+ P G S+ ++ PP+P+ Sbjct: 2675 SKTEVSATRSTAPSVGLSSISITIPPEPL 2703 Score = 53.1 bits (126), Expect = 1e-06 Identities = 78/299 (26%), Positives = 103/299 (34%), Gaps = 69/299 (23%) Query: 382 PKPRLPPPPVPP-------PLLHYPPPAKVPGLEP-----CPPPPFPPMAPPTALLQEE- 428 P + PP P+P PL P + +P PP P+ PT Q + Sbjct: 210 PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269 Query: 429 ---PL-------------------FSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPA 466 PL P P P+ PP +P PA P +S P PA Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329 Query: 467 PTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNP 526 P P G ++P ++ KPP P K L PA P GS P Sbjct: 330 KPP----AQPSGLTKPLAQQPGTV---KPPVQPPGTTKPPAQPLGPA-KPPAQQTGSEKP 381 Query: 527 CLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP------ 580 Q P+ +PP V T + PG P P T TP P +P Sbjct: 382 SSEQ----PGPKALAQPPGVGKTPAQQPG------PAKPPTQQVGTPKPLAQQPGLQSPA 431 Query: 581 -PPGPATLAPSR---PLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 PGP T P + P +P A++ P S + + S +PGP + P QP Sbjct: 432 KAPGP-TKTPVQQPGPGKIP-AQQAGPGKTSAQQTGPTKPPSQLPGP----AKPPPQQP 484 Score = 50.8 bits (120), Expect = 5e-06 Identities = 101/427 (23%), Positives = 140/427 (32%), Gaps = 92/427 (21%) Query: 264 PSPLQLPPEDAYVGNADMIQPDLTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSF 323 PSP + P + G QP QP P PS +P + Sbjct: 299 PSPSKPPIQQPTPGKPPAQQPGHEKSQPG--------------PAKPPAQPSGLTKPLAQ 344 Query: 324 SP--VVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLLPED 381 P V + GT P P A + + PGP + + Sbjct: 345 QPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQ 404 Query: 382 PKPRLPPPP---VPPPLLHYP---PPAKVPGLEPCP-----PPPFP-------------- 416 P P PP P PL P PAK PG P P P Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464 Query: 417 -PMAPPTALL-QEEPLFSPRFPFPTVPP--APGVSPLPA--PAAFPPTPQSVPSPAPTPF 470 P PP+ L +P P+ P P PP PG + P+ P + P PQ P PA Sbjct: 465 GPTKPPSQLPGPAKP--PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAK--- 518 Query: 471 PIELLPLGYSEPAFGPCFSMPRGKPPAPSP--------------RGQKASPPTLAPATAS 516 P P P+ P + P + P+P+ G+ PPT++P+ Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ 578 Query: 517 PPTTAGSNNPC----LTQLLTAAKPEQA-----LEPPLVSSTLLRSPGSPQET-VPEFPC 566 PP+ C T+LL PE+A E +L +P T V E+ C Sbjct: 579 PPSQGLPKTICPLCNTTELLLHV-PEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLC 637 Query: 567 T----------FLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGD 616 L P P+ P+ P T + P+ ++ SP + ++ D Sbjct: 638 LNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ----D 693 Query: 617 LSSMPGP 623 LS P P Sbjct: 694 LSKAPEP 700 Score = 48.5 bits (114), Expect = 3e-05 Identities = 80/358 (22%), Positives = 114/358 (31%), Gaps = 104/358 (29%) Query: 378 LPEDPKPRLPPPPVPPPLLHYPPPAK-------------VPGLEPCPP------------ 412 L + P+P+ PPP V P LH P AK P EP P Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753 Query: 413 PPFPPMAPPTALLQEEPLFSPRFPFP-----------TVPPAPGVSPLPAPAAFPPTPQS 461 P P M PT L + + P T PP S P+ +FPPT + Sbjct: 754 PKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS-QSFPPTGEK 812 Query: 462 VPSPAPTPFPIELLPLGYSEPAF----GPCFS---------------------------- 489 V +PF + +P S+ GP Sbjct: 813 V-----SPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867 Query: 490 ---MPRGKPPAPSPR---GQKASPPTLAPATASPPTTAGSNNPCLTQLLTA--AKPEQAL 541 MP+G P P PR GQ P +P N +T + P++ + Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETV 927 Query: 542 EPPLV---------SSTLLRSPGSPQETVPEFPCTFLPPTPAPTPP-----------RPP 581 L +S L+ + G P P + PAP+ P + P Sbjct: 928 TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP 987 Query: 582 PGPATLAP-SRPLLVPKAERLSPPAPSG-SERRLSGDLSSMPGPGTLSVRVSPPQPIL 637 P PA P + P AE+L P A + +R + P + S+ P + +L Sbjct: 988 PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVL 1045 Score = 33.9 bits (76), Expect = 0.64 Identities = 44/182 (24%), Positives = 61/182 (33%), Gaps = 38/182 (20%) Query: 456 PPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPS---PRGQKASPPTLAP 512 PP Q P P P P P G P + S P K+ PP Sbjct: 209 PPLQQQPPKPIPKQ----------QGPGRDPL--QQDGTPKSISSQQPEKIKSQPPGTGK 256 Query: 513 ATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPT 572 P T +++ L A++P+ + ++ S SP + + P PP Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPA 316 Query: 573 PAPTPPRPPPGPATLAPSRPLLVPKAERLSPPA-PSGSERRLSGDLSSMPGPGTLSVRVS 631 P + PGPA PPA PSG + L+ PGT+ V Sbjct: 317 QQPGHEKSQPGPA----------------KPPAQPSGLTKPLAQQ------PGTVKPPVQ 354 Query: 632 PP 633 PP Sbjct: 355 PP 356 Score = 32.0 bits (71), Expect = 2.4 Identities = 32/124 (25%), Positives = 44/124 (35%), Gaps = 12/124 (9%) Query: 478 GYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTTAGSNNPCL-TQLLTAAK 536 G P P + PP Q PPT SP T ++P L TQ T+ Sbjct: 3852 GIERPRTAPQTEFSQFIPPQTQTESQLV-PPT------SPYTQYQYSSPALPTQAPTSYT 3904 Query: 537 PEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVP 596 + E TL SP +T P F P P P P+ PS+ +++ Sbjct: 3905 QQSHFE----QQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMVIQ 3960 Query: 597 KAER 600 + R Sbjct: 3961 QKPR 3964 Score = 30.0 bits (66), Expect = 9.2 Identities = 34/159 (21%), Positives = 56/159 (35%), Gaps = 25/159 (15%) Query: 354 SRLQARNSCPGPLDSSAFLSSDFLLPE-DPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPP 412 +R+++++ P + S F+ P+ + +L PP P Y PA Sbjct: 3845 TRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPAL--------- 3895 Query: 413 PPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTP--- 469 P PT+ Q+ V P A A TPQ P+P P P Sbjct: 3896 ----PTQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFTPQVQPTPTPQPSYQ 3951 Query: 470 FPIELLPLG--------YSEPAFGPCFSMPRGKPPAPSP 500 P +++ + Y EP + + R +P +P Sbjct: 3952 LPSQMMVIQQKPRQTTLYLEPKITSNYEVIRNQPLMIAP 3990 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 78.6 bits (192), Expect = 2e-14 Identities = 119/428 (27%), Positives = 153/428 (35%), Gaps = 74/428 (17%) Query: 260 TQSGPSP-LQLPPEDAYVGNADMIQPDLTPLQPSLDDFM--DISDFFTNSRLPQPPMPSN 316 T PSP L PE +G P Q SL F+ + S ++ P +P++ Sbjct: 662 TTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPAS 721 Query: 317 F---PEPPSFSPVVDSLFSSGT-LGPEVPPASSAMTHLSGHSRLQARNSCPGPLDSSAF- 371 PP+ P + + G LGP+ P S A + A PGP S + Sbjct: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPD-SQASPAPAPQIPAAAPLKGPGPSSSPSLP 780 Query: 372 ----LSSDFLLPEDPKPRLPP--PPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALL 425 L LP P P PP PP P + PP P L PCPPP PP P ++ Sbjct: 781 HQAPLGDSPHLPS-PHPTRPPSRPPSRPQSVSRPPSE--PPLHPCPPPQAPPTLPGIFVI 837 Query: 426 QEEPLFSPRFPFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFG 485 Q + P P PAP P P P PQS P P P L P S Sbjct: 838 QNQLGVPP----PASNPAP---TAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVAS 890 Query: 486 PCFSMPRGKPPAPS-----------PRGQKASPPT--LAPATASPPTTAGSNNPCLTQLL 532 + R P PS P PPT L P A+PP +T Sbjct: 891 SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPF 950 Query: 533 TA-AKPEQALE--PPLVSSTLLR-----SPGSPQETVPEFPCTF---------LPPTPAP 575 A +P+ LE + S +L+ +P +PQ + P T P+ P Sbjct: 951 PALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTP 1010 Query: 576 TPPRPPPGPATLAPS--RPLL---------------VPKAERLSPPAPSGSERRLSGDLS 618 T P P PA +A + PLL V KA P PSG + LS Sbjct: 1011 TAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQ--YESKLS 1068 Query: 619 SMPGPGTL 626 + P TL Sbjct: 1069 GLKKPPTL 1076 Score = 67.4 bits (163), Expect = 5e-11 Identities = 77/288 (26%), Positives = 98/288 (34%), Gaps = 71/288 (24%) Query: 388 PPPVPPPLLHYPP----PAKVPGLEPCPPPPF---PPMAPPTALLQEEPL---------- 430 PP P P PP P PGL P PP A PTA+L ++ L Sbjct: 647 PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ 706 Query: 431 --FSPRFPFPTVP-------PAPGVSPLPA-PAAF-----PPTPQSVPSPAPTPFPIELL 475 S P +VP P P P PA P A P P S SPAP P Sbjct: 707 QPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAA 766 Query: 476 PLGYSEPAFGPCFSMPRGKP-------PAPSPRGQKASPPTLAPATASPPTTAGSNNPCL 528 PL P+ P S+P P P+P P + PP+ + + PP+ Sbjct: 767 PLKGPGPSSSP--SLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS--------- 815 Query: 529 TQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRPP-PGPATL 587 EPPL P P + P P F+ PP P P Sbjct: 816 -------------EPPL-------HPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAP 855 Query: 588 APSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQP 635 P +P L P+++ P P S S++ S R+ P P Sbjct: 856 GPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTP 903 Score = 66.6 bits (161), Expect = 9e-11 Identities = 86/304 (28%), Positives = 108/304 (35%), Gaps = 77/304 (25%) Query: 377 LLPEDPKPRLPPP-PVPPPLLHYPPPAKVPGLEPCPPPPFPPM----------------- 418 +L P P+ PP P PL P A+ P P P PP Sbjct: 618 VLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKI 677 Query: 419 -------APPTALLQEEPL------------FSPRFPFPTVP-------PAPGVSPLPA- 451 A PTA+L ++ L S P +VP P P P PA Sbjct: 678 VLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPAT 737 Query: 452 PAA-----FPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKP-------PAPS 499 P A P P S SPAP P PL P+ P S+P P P+P Sbjct: 738 PVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSP--SLPHQAPLGDSPHLPSPH 795 Query: 500 PRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQE 559 P + PP+ P + S P + +PC P QA PP + + Q Sbjct: 796 PTRPPSRPPS-RPQSVSRPPSEPPLHPC--------PPPQA--PPTLPGIFVI---QNQL 841 Query: 560 TVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSS 619 VP P P AP PP+PP P + P PL P A L P + S + S S Sbjct: 842 GVP--PPASNPAPTAPGPPQPPLRPQSQPPEGPL--PPAPHLPPSSTSSAVASSSETSSR 897 Query: 620 MPGP 623 +P P Sbjct: 898 LPAP 901 Score = 52.4 bits (124), Expect = 2e-06 Identities = 77/279 (27%), Positives = 99/279 (35%), Gaps = 31/279 (11%) Query: 388 PPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVS 447 P V P L P + G P P P T +LQ L P Sbjct: 546 PIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQP 605 Query: 448 PLPAPAAFPPTPQSVPSPAPTPFPIEL--LPLGYSEP-AFGP-------CFSMPRGKPPA 497 PA A P PAP P LPLG +P A P + P+ P Sbjct: 606 ATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQ 665 Query: 498 PSPRGQKASPPTLA---PATASPPTTAGSNNPCLTQLLTAAKPEQAL--EPPLVS---ST 549 PSP G +SP + P +A+P TA L L + +Q L E P +S S Sbjct: 666 PSP-GLASSPEKIVLGQPPSATP--TAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASV 722 Query: 550 LLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGS 609 ++ +P Q+ P P A P+ P A+ AP+ +P A L P PS S Sbjct: 723 IVSAPPPAQDPAPATPVA----KGAGLGPQAPDSQASPAPAPQ--IPAAAPLKGPGPSSS 776 Query: 610 ----ERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDS 644 + GD +P P PP S RP S Sbjct: 777 PSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS 815 Score = 43.1 bits (100), Expect = 0.001 Identities = 59/226 (26%), Positives = 77/226 (34%), Gaps = 36/226 (15%) Query: 381 DPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSP-RFPFPT 439 DP + PPPP KV P PPPP PP + P +P R P T Sbjct: 1328 DPVHQPPPPPA---------TLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGT 1378 Query: 440 VPPAPGVSPLPAPAAF------PPTPQSVP-------SPAPTPFPIELLPLGYSEPAFGP 486 P P LP + P P+ P SPAP P ++ G Sbjct: 1379 APHCP---RLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAV 1435 Query: 487 ----CFSMPRGKPPAP-SPRGQKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQ-- 539 M +G PP P + Q P P S +P + Q ++ Q Sbjct: 1436 EDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDD 1495 Query: 540 ALEPPLVSS--TLLRSPGSPQET-VPEFPCTFLPPTPAPTPPRPPP 582 L L S+ ++L +P T P +P TPA PP P Sbjct: 1496 TLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRP 1541 Score = 34.7 bits (78), Expect = 0.37 Identities = 112/472 (23%), Positives = 149/472 (31%), Gaps = 106/472 (22%) Query: 226 VPVLLGDPEEEPGGRQLLDLNCFLSDISDTLFTMTQSGPSPLQLPPEDAYVGNADMIQPD 285 +P L G P PGG T G +P+Q+ + N Sbjct: 211 IPGLQGLPNGSPGGA-----------------TAATLGLAPIQVVGQPVMALN------- 246 Query: 286 LTPLQPSLDDFMDISDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASS 345 TP L + +S + ++ P P+ SP L L V + Sbjct: 247 -TPTSQLLAKQVPVSGYLASAAGPSEPVTL---ASAGVSPQGAGLVIQKNLSAAVATTLN 302 Query: 346 AMTHLSGHSRLQARNSCPG--PLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPPAK 403 + G A P PL + L S L+P P + P P+ P Sbjct: 303 GNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPA---PNVILHRTPTPIQPKPAGVL 359 Query: 404 VPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPG---------------VSP 448 P L P PF P A T +Q EP P P AP +S Sbjct: 360 PPKLYQLTPKPFAP-AGATLTIQGEP-----GALPQQPKAPQNLTFMAAGKAGQNVVLSG 413 Query: 449 LPAPA---------------AFPPTPQSVPSPAPTPFPIELLPLGYS--EPAFGPC---- 487 PAPA A PP P P P + LL G S PA Sbjct: 414 FPAPALQANVFKQPPATTTGAAPPQP---PGALSKPMSVHLLNQGSSIVIPAQHMLPGQN 470 Query: 488 -FSMPRGKPPAPSPRGQKASPPTLAP--ATASPPTTAGS--NNPCLT--------QLLTA 534 F +P G P P+ A P + A+ P T G NP LT L Sbjct: 471 QFLLP-GAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPV 529 Query: 535 AKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP-PPGPA-------- 585 P + S G P + + P + L PT +P P GPA Sbjct: 530 LAPHSGAHSAHILSAAPIQVGQP--ALFQMPVS-LAAGSLPTQSQPAPAGPAATTVLQGV 586 Query: 586 TLAPSRPLLVPKAERLSPPA-PSGSERRLSGDLSSMPGPGTLSVRVSPPQPI 636 TL PS ++ + L PA P+ + + L+ P P VS P P+ Sbjct: 587 TLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAP-QAPPAVSTPLPL 637 Score = 30.0 bits (66), Expect = 9.2 Identities = 41/160 (25%), Positives = 58/160 (36%), Gaps = 17/160 (10%) Query: 462 VPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPR---------GQKASPPTLAP 512 V S PI G+ P GP S G P P G P++ Sbjct: 1202 VSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTW 1261 Query: 513 ATASPPTTAGSNNPCLTQLLTAAK--PEQALEPPLVSSTLLRSP-GSPQETVPEFPCTFL 569 A AS ++ S++ L A + P + P + + RS G + E + + Sbjct: 1262 ARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKV 1321 Query: 570 PPTPAPTPP-RPPPGPATLAPSRPLLVPKAERLSPPAPSG 608 A P +PPP PATL + P P PP P+G Sbjct: 1322 VHNTALDPVHQPPPPPATLKVAEPPPRPP----PPPPPTG 1357 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 77.8 bits (190), Expect = 4e-14 Identities = 92/331 (27%), Positives = 118/331 (35%), Gaps = 64/331 (19%) Query: 299 ISDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFSSGTLGPEVPPASSAMTHLSGHSRLQA 358 + + F + P P P P F S FS GT PP T S +S + Sbjct: 501 LEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGS 560 Query: 359 RNSCP-GPLDSSAFLSSDFLLPE-DPKPRLPPP---PVPPPLLHYPPPAKVPGLEPCPPP 413 +S P GP+ +F +L DP PR P P P PPL+ P + L P PP Sbjct: 561 HSSSPAGPV---SFPPPPYLARSIDPLPRPPSPAQNPQDPPLV----PLTL-ALPPAPPS 612 Query: 414 PFPPMAPPTALLQEEPLFSPRFPFPTVP---PAPGVSPL-PAPAAFPPTPQSVPSPAPTP 469 + E P PR FP P P P PL AP PP +P+ P Sbjct: 613 SCHQNTSGSFRRPESP--RPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRL 670 Query: 470 FPIELLPL--GYSEPAFGPCFSMPRG---------------------------KPPAPSP 500 F PL + EPA +P G +PP P Sbjct: 671 FDFPPTPLEDQFEEPA--EFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP 728 Query: 501 RGQKASP-PTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQE 559 SP PT T + P A + T TA + E+ PP + P Sbjct: 729 FASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPAL---------PPPP 779 Query: 560 TVPEFPCTFLPPTPAPTPPRPPPGPATLAPS 590 + +FP PP+ PP PPP PA+L S Sbjct: 780 PLAKFP----PPSQPQPPPPPPPSPASLLKS 806 Score = 64.3 bits (155), Expect = 4e-10 Identities = 112/450 (24%), Positives = 140/450 (31%), Gaps = 149/450 (33%) Query: 251 DISDTLFTMTQSGPSPLQ--LPPEDAY---------VGNADMIQPDLTPLQPSLDDFMDI 299 +I + LF T+ P P LP + + VG D P TP P+ Sbjct: 499 EILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPP-TPPTPTTSS---- 553 Query: 300 SDFFTNSRLPQPPMPSNFPEPPSFSPVVDSLFS--SGTLGPEVPPASSAMTHLSGHSRLQ 357 S+ + S P P +FP PP + +D L S P+ PP L Sbjct: 554 SNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALP------ 607 Query: 358 ARNSCPGPLDSS-AFLSSDFLLPEDPKPRLP--------PPPVPPPLLHYPPP------- 401 P P S S F PE P+PR+ P P P PL P P Sbjct: 608 -----PAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGE 662 Query: 402 --AKVPGLEPCPPPPF-------------------------------------------- 415 A+ P L PP P Sbjct: 663 LPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQ 722 Query: 416 PPMAPPTALLQEEPLFSPRFPFPTVP-----------------------PAPGVSPLPAP 452 PP+ P A LQ P + P T P P P + P P Sbjct: 723 PPLKEPFASLQS-PFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPL 781 Query: 453 AAFPPTPQSVPSPAPTPFPIELLP--------LGYSEPAFGPCFSMPRGKPPAPSPRGQK 504 A FPP Q P P P P P LL Y G S P P P Q Sbjct: 782 AKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVS----TRPGPLPTTQ- 836 Query: 505 ASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSP---QETV 561 SP + ATA PPT+A A + + +P SS+ + G P + Sbjct: 837 YSPGPPSGATALPPTSA------------APSAQGSPQPSASSSSQFSTSGGPWARERRA 884 Query: 562 PEFPCTFLPPTPAPTPPRPPPGPATLAPSR 591 E P P P P PP P +L P+R Sbjct: 885 GE------EPVPGPMTPTQPPPPLSLPPAR 908 Score = 57.4 bits (137), Expect = 5e-08 Identities = 85/312 (27%), Positives = 104/312 (33%), Gaps = 75/312 (24%) Query: 311 PPMPSNFPEPPSFSPVVDSLFSSGT------LGPEVPPASSAMT---HLSGHSRL-QARN 360 P PS P P + S SS T P +P A T +S H RL + + Sbjct: 384 PYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAH 443 Query: 361 SCPGPLDSSAFLSSDFLLPEDPKPRLPPPPVPPPLLHYPPP---AKVPGLEPC------- 410 S P + + LP P P PPPP P LL PPP K P Sbjct: 444 SSRKPFLGAPAATPHLSLP--PGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEIL 501 Query: 411 ---------PPPPFPPMAPPTALLQEEPLFSPRFPFPT----VPPAPGVSPLPAPAAFPP 457 PP P PP P P + RF T PP P P P Sbjct: 502 EELFFGTEGPPRPAPPPLPHREGFLGPP--ASRFSVGTQDSHTPPTP-----PTPTTSSS 554 Query: 458 TPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASP 517 S + P+ P Y + P +PR PA +P+ P TLA A P Sbjct: 555 NSNSGSHSSSPAGPVSFPPPPYLARSIDP---LPRPPSPAQNPQDPPLVPLTLALPPA-P 610 Query: 518 PTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTP 577 P++ N +S R P SP+ P P TP Sbjct: 611 PSSCHQN----------------------TSGSFRRPESPR------PRVSFPKTP-EVG 641 Query: 578 PRPPPGPATLAP 589 P PPPGP + AP Sbjct: 642 PGPPPGPLSKAP 653 Score = 55.5 bits (132), Expect = 2e-07 Identities = 107/426 (25%), Positives = 131/426 (30%), Gaps = 117/426 (27%) Query: 308 LPQPPMPSNFPEPPSFSPVVDSLFSS-----------GTL-----GPE----VPPASSAM 347 LP PP+P P PP P + L +S TL GPE PP Sbjct: 246 LPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQ 305 Query: 348 THLSGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPP--PPVPPPLLHYPPPAKVP 405 H H P P + A+ + P RL P PP P P PP A+ Sbjct: 306 RHSLPH---------PYPYPAPAYTA------HPPGHRLVPAAPPGPGP---RPPGAESH 347 Query: 406 GLEPCPPPPFPPM----------------APPTALLQEEPLFSPRFPFPTV--------- 440 G P PP + A TA + P P P T Sbjct: 348 GCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSN 407 Query: 441 ---------PPAPGVSPLPAPA-------AFPPTPQSVPSP---APTPFPIELLPLGYSE 481 P PG PA P+ S P AP P LP G S Sbjct: 408 TGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSS 467 Query: 482 PAFGPCFSMPRGKPP-----APSPRGQKASPPTL-----------APATASPPTTAGSNN 525 P PC + R PP P+ R + L PA P G Sbjct: 468 PPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLG 527 Query: 526 PCLTQLLTAAKPEQA-LEPPLVSSTLLRSPGSPQETVPEFPCTFLPP-------TPAPTP 577 P ++ + PP +++ S + P P +F PP P P P Sbjct: 528 PPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRP 587 Query: 578 PRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVRVS-PPQPI 636 P P P P LVP L P PS + SG S P + RVS P P Sbjct: 588 PSPAQN-----PQDPPLVPLTLALPPAPPSSCHQNTSG---SFRRPESPRPRVSFPKTPE 639 Query: 637 LSRGRP 642 + G P Sbjct: 640 VGPGPP 645 Score = 53.5 bits (127), Expect = 8e-07 Identities = 59/204 (28%), Positives = 76/204 (37%), Gaps = 40/204 (19%) Query: 382 PKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQE--EPLFSPRF---- 435 P P LPPPP PL +PPP+ +P PPPP PP P +LL+ L ++ Sbjct: 771 PPPALPPPP---PLAKFPPPS-----QPQPPPPPPP--SPASLLKSLASVLEGQKYCYRG 820 Query: 436 ----------PFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFG 485 P PT +PG P A PPT + PS +P P +S G Sbjct: 821 TGAAVSTRPGPLPTTQYSPG--PPSGATALPPT-SAAPSAQGSPQPSASSSSQFSTSG-G 876 Query: 486 PCFSMPR-GKPPAPSPRGQKASPP--TLAPATASPPTTAGSNNPCLT-------QLLTAA 535 P R G+ P P P PP +L PA + + C T A Sbjct: 877 PWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPA 936 Query: 536 KPEQALEPPLVSSTLLRSPGSPQE 559 P EP + L P +E Sbjct: 937 DPVDTAEPADSGTERLLPPAQAKE 960 Score = 52.8 bits (125), Expect = 1e-06 Identities = 74/265 (27%), Positives = 90/265 (33%), Gaps = 34/265 (12%) Query: 384 PRLPPPPVPPPLLHYPPPAKVPGLEPCPPPPFPPMA-PPTALLQEEPLFSPRFPFPTVPP 442 P PPP PPP PPP P PPPP P +A P L + L+S P Sbjct: 245 PLPPPPLPPPP----PPP-------PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPE 293 Query: 443 APGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRG 502 G AP S+P P P P P + A P + PP P PR Sbjct: 294 RKG----SAPPERQEQRHSLPHPYPYPAP--------AYTAHPPGHRLVPAAPPGPGPRP 341 Query: 503 QKASPPTLAPATASPPTTAGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVP 562 A PAT P + + +++ ++ P A V R PG P T Sbjct: 342 PGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSP--AATTACVPYAPSRPPGLPGTTTS 399 Query: 563 EFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSG-----DL 617 + P P A + L V RL P A S + L L Sbjct: 400 SSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHL 459 Query: 618 SSMPGPGTLSVRVSPPQPILSRGRP 642 S PGP S PP P L R P Sbjct: 460 SLPPGP---SSPPPPPCPRLLRPPP 481 Score = 30.0 bits (66), Expect = 9.2 Identities = 25/66 (37%), Positives = 30/66 (45%), Gaps = 12/66 (18%) Query: 570 PPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGSERRLSGDLSSMPGPGTLSVR 629 PP PAP PP G ++ PS+P P A P P R L G L S+ G +R Sbjct: 54 PPLPAPLPPSH--GSSSGHPSKPYYAPGA-----PTP----RPLHGKLESLHGCVQALLR 102 Query: 630 VSPPQP 635 P QP Sbjct: 103 -EPAQP 107 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.135 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 46,865,201 Number of Sequences: 37866 Number of extensions: 3518403 Number of successful extensions: 72345 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 660 Number of HSP's successfully gapped in prelim test: 2115 Number of HSP's that attempted gapping in prelim test: 21711 Number of HSP's gapped (non-prelim): 20978 length of query: 831 length of database: 18,247,518 effective HSP length: 111 effective length of query: 720 effective length of database: 14,044,392 effective search space: 10111962240 effective search space used: 10111962240 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.