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Search of human proteins with 145580595
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo
sapiens]
(446 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sa... 893 0.0
gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo s... 893 0.0
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 95 1e-19
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 92 1e-18
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 91 2e-18
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 87 2e-17
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 82 1e-15
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 78 2e-14
gi|148746195 trichohyalin [Homo sapiens] 77 4e-14
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 76 7e-14
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 75 2e-13
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 72 8e-13
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 71 2e-12
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 71 2e-12
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 71 2e-12
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 71 2e-12
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 70 4e-12
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 70 4e-12
gi|55770834 centromere protein F [Homo sapiens] 70 5e-12
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 69 7e-12
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 69 7e-12
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 69 7e-12
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 69 7e-12
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 69 1e-11
gi|31377611 coiled-coil domain containing 148 [Homo sapiens] 68 1e-11
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 66 6e-11
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 65 2e-10
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 65 2e-10
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 65 2e-10
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 65 2e-10
>gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo
sapiens]
Length = 529
Score = 893 bits (2307), Expect = 0.0
Identities = 446/446 (100%), Positives = 446/446 (100%)
Query: 1 MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLK 60
MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLK
Sbjct: 84 MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLK 143
Query: 61 DVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWAL 120
DVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWAL
Sbjct: 144 DVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWAL 203
Query: 121 GNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRN 180
GNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRN
Sbjct: 204 GNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRN 263
Query: 181 KHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIF 240
KHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIF
Sbjct: 264 KHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIF 323
Query: 241 KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK 300
KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK
Sbjct: 324 KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK 383
Query: 301 EKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQE 360
EKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQE
Sbjct: 384 EKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQE 443
Query: 361 RDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIG 420
RDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIG
Sbjct: 444 RDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIG 503
Query: 421 PTGSGPLLHIPHRAIPTWRQGIQRRV 446
PTGSGPLLHIPHRAIPTWRQGIQRRV
Sbjct: 504 PTGSGPLLHIPHRAIPTWRQGIQRRV 529
>gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo
sapiens]
Length = 446
Score = 893 bits (2307), Expect = 0.0
Identities = 446/446 (100%), Positives = 446/446 (100%)
Query: 1 MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLK 60
MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLK
Sbjct: 1 MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLK 60
Query: 61 DVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWAL 120
DVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWAL
Sbjct: 61 DVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWAL 120
Query: 121 GNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRN 180
GNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRN
Sbjct: 121 GNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRN 180
Query: 181 KHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIF 240
KHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIF
Sbjct: 181 KHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIF 240
Query: 241 KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK 300
KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK
Sbjct: 241 KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK 300
Query: 301 EKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQE 360
EKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQE
Sbjct: 301 EKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQE 360
Query: 361 RDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIG 420
RDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIG
Sbjct: 361 RDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIG 420
Query: 421 PTGSGPLLHIPHRAIPTWRQGIQRRV 446
PTGSGPLLHIPHRAIPTWRQGIQRRV
Sbjct: 421 PTGSGPLLHIPHRAIPTWRQGIQRRV 446
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 95.1 bits (235), Expect = 1e-19
Identities = 97/448 (21%), Positives = 211/448 (47%), Gaps = 54/448 (12%)
Query: 6 HSHFYNQKSDFRIEHSMLEELENKL--IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVK 63
HS QK+ + + ++ ELE ++ I ++ ++Q L + VK+L+ + +D+
Sbjct: 105 HSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI 164
Query: 64 PTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNS 123
K +E+ +A+ T K++ EEL KE + EL + + N+
Sbjct: 165 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 224
Query: 124 ETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHK 183
+ ++ + + S+ ++ L + L+ K L Q ++ H
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRK-LERAKLLLP-------------QQQLQAEADHL 270
Query: 184 GKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEE---RKKESIQIWKTKKQQKREEIF 240
GK L+ + K Q +V+++E W + EE R++E IQ W+ K Q++ E+I
Sbjct: 271 GKE------LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
Query: 241 KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVE-----------AWKKQKSI---EM 286
+ +EK ++E +++E+ R+++++ E W+K++ I E
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE 384
Query: 287 SMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKK--EQEEFLR-LEKEIREKAE 343
M +++E+EEK ++ +K R+++ + + + + Q++K EQEE +R EK++ + E
Sbjct: 385 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEE 444
Query: 344 KAEKRKNAADEISRFQERDLHKLELKILDRQA--KEDEKSQKQRRLAKLKEKV------- 394
K +++ +E R ++ ++ + E KI +++ ++ EK +Q ++ K +EKV
Sbjct: 445 KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
Query: 395 ---ENNVSRDPSRLYKPTKGWEERTKKI 419
E + ++++ + E+ +KI
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKI 532
Score = 82.8 bits (203), Expect = 6e-16
Identities = 92/404 (22%), Positives = 193/404 (47%), Gaps = 54/404 (13%)
Query: 25 ELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAIN 84
EL N+L + + K+ +Q KI +K+Q Q EK+RE E+I
Sbjct: 289 ELWNRL---NQQQEEKMWRQEEKIQEWEEKIQEQ----------EEKIREQEEKIREQEE 335
Query: 85 TFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPS 144
+ ++ +++E KEEK E W E E+ R + + +
Sbjct: 336 KMRRQEEMMWE---KEEKMRRQEEMM-------W-----EKEEKMRRLEEMMWEKEEKIR 380
Query: 145 TLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEV 204
L E++ + EK +Q RQ + + R + + K EE + K +++
Sbjct: 381 ELEEKMHEQEKIREQEEKRQEEEKIREQEK----RQEQEAKMWRQEEKIREQEEKIREQE 436
Query: 205 Q----QHEKWY-QKFLALEERKKESIQIWKTKKQ-QKREEIFKLKEKADNTPVLFHNKQE 258
+ Q EK + Q+ + EE+++E ++W+ +++ +++EEI++ KEK H +++
Sbjct: 437 KKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK-------MHEQEK 489
Query: 259 DNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK-EKKHQKERQRQFKLKLL 317
+++++ R+++K+ + K ++ E + +++E+EEK ++ +K R+++ ++
Sbjct: 490 IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ 549
Query: 318 LESYTQQK---KEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQ 374
E +Q+ +EQE+ R E++IRE+ EK ++K E R QE + + E KI +++
Sbjct: 550 EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK----EKIREQEEKIWEQEEKIREQE 605
Query: 375 AKEDEKSQKQ-RRLAKLKEKVENNVSRDPSRLYKPTKGWEERTK 417
E+ +K + K+ E+ E ++ + K WE+ +
Sbjct: 606 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 649
Score = 55.5 bits (132), Expect = 1e-07
Identities = 71/327 (21%), Positives = 154/327 (47%), Gaps = 36/327 (11%)
Query: 1 MEKDKHSHFYNQKSDFRIEHSMLE------ELENKLIHSRKT-ERAKIQQQLAKIHNNVK 53
M + + + ++ R+E M E ELE K+ K E+ + +Q+ KI K
Sbjct: 351 MRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 410
Query: 54 KLQHQLKDVKPTPDFVEKLREMMEEI-ENAINTFKEEQRLIYEELIKEE--KTTNNELSA 110
+ + + K + EK+RE E+I E +++E+++ +E I+EE + E+
Sbjct: 411 RQEQEAKMWRQE----EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 466
Query: 111 ISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDY 170
KI + EK + +KV E++ D E+ +++ + ++
Sbjct: 467 QEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE--EKMHDQEEKIREQEEKMWRQEEK 524
Query: 171 DHQNFVKVRNKHKGKPTFMEEVL---EHLPGKTQDEVQQHEKWYQKFLALEERKKESIQI 227
+ K+R + + K EE++ E G+ ++++Q+ EK ++ + E++ E I+
Sbjct: 525 IREQEEKIREQEE-KIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQE-EKIRE 582
Query: 228 WKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMS 287
K K +++ E+I++ +EK ++E Q+Q+E+ ++++ E +K + E
Sbjct: 583 QKEKIREQEEKIWEQEEK-------IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 635
Query: 288 MKCASQ--------LKEEEEKEKKHQK 306
M+ + L+++EEK ++HQ+
Sbjct: 636 MRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 52.8 bits (125), Expect = 6e-07
Identities = 72/377 (19%), Positives = 166/377 (44%), Gaps = 20/377 (5%)
Query: 1 MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSR---KTERAKIQQQLAKIHNNVKKLQH 57
+ + + + Q+ + ++E E K+ + + K+++Q + +K++
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 58 QLKDVKPTPDFVEKLREMMEEIENAINTFKE---EQRLIYEELIKEEKTTNNELSAISRK 114
Q + + + + +L EMM E E I +E EQ I E+ EEK E K
Sbjct: 354 QEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQ---EEKRQEEEKIREQEK 410
Query: 115 IDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQN 174
E+ R K+ + E++ + EK +++ RQ + + +
Sbjct: 411 RQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK-IREEEKRQEQEEMWRQEE 469
Query: 175 FVKVRN---KHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEE---RKKESIQIW 228
++ + + K K E++ + + E + H++ +K EE R++E I+
Sbjct: 470 KIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ-EEKIREQEEKMWRQEEKIREQ 528
Query: 229 KTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSM 288
+ K +++ E+I + +E ++E Q+Q++ +R+++K+ + K ++ E
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIR 588
Query: 289 KCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKA-EK 347
+ ++ E+EEK + Q+E ++ + K + E + +++E+ E+++R + EK E+
Sbjct: 589 EQEEKIWEQEEKI-REQEEMMQEQEEK-MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 646
Query: 348 RKNAADEISRFQERDLH 364
+ + QE H
Sbjct: 647 EVRLRQQEEKMQEHQEH 663
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 91.7 bits (226), Expect = 1e-18
Identities = 90/436 (20%), Positives = 206/436 (47%), Gaps = 50/436 (11%)
Query: 6 HSHFYNQKSDFRIEHSMLEELENKL--IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVK 63
HS QK+ + + ++ ELE ++ I ++ ++Q L + VK+L+ + +D+
Sbjct: 166 HSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI 225
Query: 64 PTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNS 123
K +E+ +A+ T K++ EEL KE + EL + + N+
Sbjct: 226 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 285
Query: 124 ETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHK 183
+ ++ + + S+ ++ L + L+ K L Q ++ H
Sbjct: 286 KLQEKLQLVESEKSEIQLNVKELKRK-LERAKLLLP-------------QQQLQAEADHL 331
Query: 184 GKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEE---RKKESIQIWKTKKQQKREEIF 240
GK L+ + K Q +V+++E W + EE R++E IQ W+ K Q++ E+I
Sbjct: 332 GKE------LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 385
Query: 241 KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVE-----------AWKKQKSI---EM 286
+ +EK ++E +++E+ R+++++ E W+K++ I E
Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445
Query: 287 SMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAE 346
M +++E+EEK ++ +K R+++ + + + + Q++K +E+ E++IRE+ EK
Sbjct: 446 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ----EEKIREQEEKMW 501
Query: 347 KRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKV---ENNVSRDPS 403
+++ E + +E + + + + +++EK ++Q + + KEK+ E + +
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQ----EEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE 557
Query: 404 RLYKPTKGWEERTKKI 419
++++ + ++ +KI
Sbjct: 558 KMWRQEEKMHDQEEKI 573
Score = 84.0 bits (206), Expect = 3e-16
Identities = 78/372 (20%), Positives = 183/372 (49%), Gaps = 37/372 (9%)
Query: 25 ELENKLIHSRKT----ERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIE 80
EL N+L ++ + KIQ+ KI +K++ Q + ++ + + + EMM E E
Sbjct: 350 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 409
Query: 81 NAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKV---- 136
+ + ++ +++E KEEK E W E E+ R + K+
Sbjct: 410 EKM---RRQEEMMWE---KEEKMRRQEEMM-------W-----EKEEKIRELEEKMHEQE 451
Query: 137 PVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHL 196
+ + EE + ++ Q+ + ++ + K+R + + E++ E
Sbjct: 452 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQE 511
Query: 197 PGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQ--QKREEIFKLKEKADNTPVLFH 254
+ +++ Q+ E+ +++ EE+ +E +IW+ K++ ++ E+I K +EK H
Sbjct: 512 KIREEEKRQEQEEMWRQ----EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH 567
Query: 255 NKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKL 314
+++E ++Q+E+ ++++ E +K + E ++ ++ +E+E++ Q+E+ + +
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 627
Query: 315 KLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQ 374
K + E + ++++E+ EK+IRE+ EK ++ +E+ + QE + + E K+ +++
Sbjct: 628 K-MQEQEEKMRRQEEKIREQEKKIREQEEKIREQ----EEMMQEQEEKMWEQEEKMCEQE 682
Query: 375 AKEDEKSQKQRR 386
K E+ +K RR
Sbjct: 683 EKMQEQEEKMRR 694
Score = 72.4 bits (176), Expect = 8e-13
Identities = 85/395 (21%), Positives = 183/395 (46%), Gaps = 42/395 (10%)
Query: 34 RKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIE--NAINTFKEEQR 91
RK ERAK+ ++ L +L+ V KL+ +EE E N +N +EE+
Sbjct: 310 RKLERAKLLLPQQQLQAEADHLGKELQSVSA------KLQAQVEENELWNRLNQQQEEKM 363
Query: 92 LIYEELIKE--EKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEE 149
EE I+E EK E KI E E+ R ++ +K EE
Sbjct: 364 WRQEEKIQEWEEKIQEQE-----EKIREQEEKIREQEEKMRR-QEEMMWEKEEKMRRQEE 417
Query: 150 VLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEK 209
++ +EK + + W+ + K+R + K E++ E + ++E + ++
Sbjct: 418 MM-WEKEEKMRRQEEMMWEKEE-----KIRELEE-KMHEQEKIREQEEKRQEEEKIREQE 470
Query: 210 WYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRK 269
Q+ A R++E I+ + K +++ E++++ +EK + ++ Q++ Q +
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 530
Query: 270 KQKLAVEAWKKQKSIEMSMKCASQLKEEEEK-----EKKHQKERQRQFKLKLLLESYTQQ 324
K + E W++++ I + +++++EEK EK H +E + + E +
Sbjct: 531 KIREQEEIWRQKEKIHEQEE---KIRKQEEKMWRQEEKMHDQEEK-------IREQEEKV 580
Query: 325 KKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQ 384
+++E+ E++IRE+ EK ++ +E+++ QE + + E K+ +++ K E+ +K
Sbjct: 581 WRQEEKIREQEEKIREQEEKIREQ----EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636
Query: 385 RRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKI 419
RR + + E + ++ + + +E+ +K+
Sbjct: 637 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671
Score = 52.0 bits (123), Expect = 1e-06
Identities = 69/375 (18%), Positives = 170/375 (45%), Gaps = 32/375 (8%)
Query: 11 NQKSDFRI--EHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDF 68
NQ+ + ++ + ++E E K+ + + KI++Q KI +K++ Q + + +
Sbjct: 356 NQQQEEKMWRQEEKIQEWEEKI----QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 411
Query: 69 VEKLREMMEEIENAINTFKE------------EQRLIYEELIKEEKTTNNELSAI--SRK 114
+ + EMM E E + +E E+++ +E I+E++ E I K
Sbjct: 412 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 471
Query: 115 IDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQN 174
E+ R K+ + E++ + EK +++ RQ + + +
Sbjct: 472 RQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEK-IREEEKRQEQEEMWRQEE 530
Query: 175 FVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQ 234
++ + + + + E E + + + +Q EK + + + E++++ +W+ ++++
Sbjct: 531 KIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEK---VWR-QEEK 586
Query: 235 KREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRK----KQKLAVEAWKKQKSIEMSMKC 290
RE+ K++E+ + QE +K E++ K ++K+ + K ++ E +
Sbjct: 587 IREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ 646
Query: 291 ASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKA-EKRK 349
+++E+EEK + Q+E ++ + K + E + +++E+ E+++R + EK E+
Sbjct: 647 EKKIREQEEKI-REQEEMMQEQEEK-MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704
Query: 350 NAADEISRFQERDLH 364
+ + QE H
Sbjct: 705 RLRQQEEKMQEHQEH 719
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 90.9 bits (224), Expect = 2e-18
Identities = 95/428 (22%), Positives = 203/428 (47%), Gaps = 34/428 (7%)
Query: 6 HSHFYNQKSDFRIEHSMLEELENKL--IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVK 63
HS QK+ + + ++ ELE ++ I ++ ++Q L + VK+L+ + +D+
Sbjct: 105 HSPEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI 164
Query: 64 PTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNS 123
K +E+ +A+ T K++ EEL KE + EL + + N+
Sbjct: 165 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 224
Query: 124 ETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHK 183
+ ++ + + S+ ++ L + L+ K L Q ++ H
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRK-LERAKLLLP-------------QQQLQAEADHL 270
Query: 184 GKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEE---RKKESIQIWKTKKQQKREEIF 240
GK L+ + K Q +V+++E W + EE R++E IQ W+ K Q++ E+I
Sbjct: 271 GKE------LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR 324
Query: 241 KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSM--KCASQLKEEE 298
+ +EK ++E +++E+ R+++++ E +K + E M K ++EE
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
Query: 299 EKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAE----KAEKRKNAADE 354
+K +K R+ + K+ + Q++K QEE E+E R++ E + E++ +E
Sbjct: 385 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444
Query: 355 ISRFQERDLHKLELKILDRQ-AKEDEKSQKQRRLAKLKEKV--ENNVSRDPSRLYKPTKG 411
R QE+ + + E KI +++ +E+EK Q+Q + + +EK+ + + R ++++ +
Sbjct: 445 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
Query: 412 WEERTKKI 419
++ +K+
Sbjct: 505 IRKQEEKV 512
Score = 82.4 bits (202), Expect = 8e-16
Identities = 84/429 (19%), Positives = 201/429 (46%), Gaps = 27/429 (6%)
Query: 3 KDKHSHFYNQKSDFRIEHSMLEELENKLIHSR-----KTERAKIQQQLAKIHNNVKKLQH 57
+++ Q+ R + M+ E E K+ K E+ + Q+++ + Q
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 383
Query: 58 QLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISR---K 114
++ K EK+RE+ E++ ++E++ EE I+E++ + + + R K
Sbjct: 384 EMMWEKE-----EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 438
Query: 115 IDTWALGNSETEKAFRAISSKV-PVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYD-- 171
I E EK K+ +K+ +E + + ++ ++ W +
Sbjct: 439 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM 498
Query: 172 HQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWK-T 230
H+ K+R K + K EE + K ++ Q+ + W Q EE+ +E ++W+
Sbjct: 499 HEQEEKIR-KQEEKVWRQEEKIREQEEKIRE--QEEKMWRQ-----EEKIREQEEMWREE 550
Query: 231 KKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKC 290
+K ++E+I++ +++ + ++ +++ +++++ R+++K+ + K+Q+ E K
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 291 ASQLKEEEEK-EKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRK 349
+++E+EEK +++ +K R+++ K++ E +Q+++ E E EK ++ E+
Sbjct: 611 EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETM 670
Query: 350 NAADEISRFQERDLHKLELKILDRQAKEDEKSQKQ-RRLAKLKEKVENNVSRDPSRLYKP 408
+E R QE+ + + E KI +++ E+ +K + K+ E+ E ++ +
Sbjct: 671 WRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Query: 409 TKGWEERTK 417
K WE+ +
Sbjct: 731 EKMWEQEVR 739
Score = 77.8 bits (190), Expect = 2e-14
Identities = 89/423 (21%), Positives = 196/423 (46%), Gaps = 48/423 (11%)
Query: 25 ELENKLIHSRKT----ERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIE 80
EL N+L ++ + KIQ+ KI +K++ Q + ++ + + + EMM E E
Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
Query: 81 NAINTF------KEEQRLIYEELI--KEEKTTNNELSAISRKIDTWALGNSETEKAFRAI 132
+ KEE+ EE++ KEEK E W E E+ R +
Sbjct: 349 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM-------W-----EKEEKIREL 396
Query: 133 SSKV----PVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTF 188
K+ + + EE + ++ Q+ + ++ + K+R + K
Sbjct: 397 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 456
Query: 189 MEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQ--QKREEIFKLKEKA 246
E++ E + +++ Q+ E+ +++ EE+ E +IW+ K++ ++ E+I K +EK
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQ----EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 247 DNTPVLFHNKQEDNQKQKEE---QRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKK 303
++E ++Q+E+ Q +K + E W++++ + K + EEE+++++
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK----IWEEEKRQEQ 568
Query: 304 HQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDL 363
K +++ K++ E +Q+++ E +E EK K E++ +E + QE +
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
Query: 364 HKLELKILDR----QAKEDEKSQKQRRLAKLKEKV---ENNVSRDPSRLYKPTKGWEERT 416
+ E KI ++ Q +E++ +++ ++ + +EK+ E + R ++ + K E+
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688
Query: 417 KKI 419
+KI
Sbjct: 689 EKI 691
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 87.4 bits (215), Expect = 2e-17
Identities = 88/419 (21%), Positives = 194/419 (46%), Gaps = 26/419 (6%)
Query: 6 HSHFYNQKSDFRIEHSMLEELENKL--IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVK 63
HS QK+ + + ++ ELE ++ I ++ ++Q L + VK+L+ + +D+
Sbjct: 93 HSPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLI 152
Query: 64 PTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNS 123
K +E+ +A+ T K++ EEL KE + EL + + N+
Sbjct: 153 SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA 212
Query: 124 ETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHK 183
+ ++ + + S+ ++ L + L+ K L Q ++ H
Sbjct: 213 KLQEKLQLVESEKSEIQLNVKELKRK-LERAKLLLP-------------QQQLQAEADHL 258
Query: 184 GKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEE---RKKESIQIWKTKKQQKREEIF 240
GK L+ + K Q +V+++E W + EE R++E IQ + K Q++ E+I
Sbjct: 259 GKE------LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIR 312
Query: 241 KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK 300
+ +EK + K+E ++Q+E +K++ E +K E ++ + ++EEEK
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQEEKRQEEEK 371
Query: 301 EKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQE 360
++ +K ++++ K+ E +Q+++ E + +E EK + E++ +E + QE
Sbjct: 372 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431
Query: 361 RDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKI 419
+ + E KI +++ K E+ +K R ++ ++ E + ++ + +E+ +K+
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKM 490
Score = 74.7 bits (182), Expect = 2e-13
Identities = 68/362 (18%), Positives = 173/362 (47%), Gaps = 31/362 (8%)
Query: 35 KTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQ-RLI 93
K + AK+Q++L + + ++Q +K++K ++E A ++Q +
Sbjct: 208 KEKNAKLQEKLQLVESEKSEIQLNVKELK-------------RKLERAKLLLPQQQLQAE 254
Query: 94 YEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDF 153
+ L KE ++ + +L A + + W N + E+ K+ + E++ +
Sbjct: 255 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQ 314
Query: 154 EKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQK 213
E+ +++ ++ + + K + E++ E + Q+E +Q E +K
Sbjct: 315 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE---EK 371
Query: 214 FLALEERKKESIQIWKTKKQQKREE---------IFKLKEKADNTPVLFHNKQEDNQKQK 264
E+R+++ ++W+ +++ + +E + + +EK ++E+ Q+Q+
Sbjct: 372 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431
Query: 265 EEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQ 324
E+ R++++ E KK + E ++ ++ +E+E++ Q+ + + + K + E +
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK-MQEQEEKM 490
Query: 325 KKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQ 384
++++E+ EK+IRE+ EK ++ +E+ + QE + + E K+ +++ K E+ +K
Sbjct: 491 RRQEEKIREQEKKIREQEEKIREQ----EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 546
Query: 385 RR 386
RR
Sbjct: 547 RR 548
Score = 64.3 bits (155), Expect = 2e-10
Identities = 79/379 (20%), Positives = 171/379 (45%), Gaps = 60/379 (15%)
Query: 34 RKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIE--NAINTFKEEQR 91
RK ERAK+ ++ L +L+ V KL+ +EE E N +N +EE+
Sbjct: 237 RKLERAKLLLPQQQLQAEADHLGKELQSVSA------KLQAQVEENELWNRLNQQQEEKM 290
Query: 92 LIYEELIKE---------EKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVT 142
EE I+E EK E ++ W E E+ R + +
Sbjct: 291 WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMW-----EKEEKMRRQEEMMWEKEEK 345
Query: 143 PSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQD 202
L E++ + EK +Q RQ + + R + + K EE + K ++
Sbjct: 346 IRELEEKMHEQEKIREQEEKRQEEEKIREQEK----RQEQEAKMWRQEEKIREQEEKIRE 401
Query: 203 EVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQK 262
+ + ++ +K EE+ E + + ++++ R + K++E QE +
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE------------QEKKIR 449
Query: 263 QKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEK-KHQKERQRQFKLKLLLESY 321
++EE+ ++Q+ ++ +++ + C + K +E++EK + Q+E+ R+ + K+
Sbjct: 450 EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKI----- 504
Query: 322 TQQKKEQEEFLRLEKEIREKAEKA--EKRKNAADEISRFQERDLHKLELKILDRQAKEDE 379
+EQEE +R ++E+ ++ E+ E+ + ++ + QE++ ++ +++E
Sbjct: 505 ----REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE---------EKMRRQEE 551
Query: 380 KSQKQR-RLAKLKEKVENN 397
K ++Q RL + +EK++ +
Sbjct: 552 KMREQEVRLRQQEEKMQEH 570
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 82.0 bits (201), Expect = 1e-15
Identities = 95/436 (21%), Positives = 199/436 (45%), Gaps = 40/436 (9%)
Query: 2 EKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKD 61
E++K QK + E ++ + R E+ K+ +Q+ K+ KK+Q Q
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE-KKMQEQ--- 435
Query: 62 VKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALG 121
K T D EK++E E I +EE+ + E+ EEK E + ++ W
Sbjct: 436 EKKTRDQEEKMQEE-ERIREREKKMREEEETMREQ---EEKMQKQEENMWEQEEKEWQQQ 491
Query: 122 NSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGG--RQGAWDDYDHQNFVKVR 179
+K K+ + E++ D E+ Q RQ + + Q + +
Sbjct: 492 RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ-E 550
Query: 180 NKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKF-LALEERKKESIQIWKTKKQQKREE 238
K + + M + E + KTQ+ Q+ + W Q+ + EER +E + + +++ RE+
Sbjct: 551 EKMRDQEQKMWDQEERMEKKTQE--QEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608
Query: 239 IFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEE 298
K++E+ + E +K +E++ K + + W++++ + + Q ++
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 299 EKEKKHQKERQRQFKLKL----LLESYTQQKKEQ---EEFLRLEKEIREKAEKAEKRKNA 351
E EK ++E+ ++ + K+ +E TQ+++++ +E +R E+ +RE+ EK+
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER----EKKMRE 724
Query: 352 ADEISRFQERDLHKLELKILDRQA----------KEDEKSQKQRRLAKLKEKVENNVSRD 401
+E+ R QE + + E K+ +++ +++EK +Q+RL + KEK+ +
Sbjct: 725 EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH---- 780
Query: 402 PSRLYKPTKGWEERTK 417
++ + K WE+ K
Sbjct: 781 -EKMQEQEKIWEQEEK 795
Score = 69.3 bits (168), Expect = 7e-12
Identities = 84/442 (19%), Positives = 205/442 (46%), Gaps = 30/442 (6%)
Query: 1 MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKL--QHQ 58
M+K + + + ++ ++ + L E + KL E+ K+Q+Q KI +K+ Q +
Sbjct: 473 MQKQEENMWEQEEKEW--QQQRLPEQKEKL-----WEQEKMQEQEEKIWEQEEKIRDQEE 525
Query: 59 LKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNN---------ELS 109
+ + EK+RE +++ +++++ ++++ + EK T E
Sbjct: 526 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM 585
Query: 110 AISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDD 169
++ E E+ R K+ + E++ + E+ +Q+ + ++
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Query: 170 YDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEK--WYQKFLALEERKKESIQI 227
+ K+ + + P E++ EH + Q+++Q+ E+ W Q+ + + +++E +
Sbjct: 646 KMWEQEEKMWEQQR-LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK-KT 703
Query: 228 WKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMS 287
W +K ++ E + + ++K + ++E Q+Q+E+ +++++ E +K E
Sbjct: 704 WDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Query: 288 MKCASQLKEEEEKEKKHQK--ERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKA 345
M +L E++EK +H+K E+++ ++ + + ++ + QEE +R ++E K
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEE---KMRGQ 820
Query: 346 EKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRL 405
E++ +E QE + E K+ ++ K +EK Q Q K++E+ E + ++
Sbjct: 821 EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEE--KMREQ-EEKMRGQEEKM 877
Query: 406 YKPTKGWEERTKKIGPTGSGPL 427
+ + + +KI GS P+
Sbjct: 878 REQEEKMRGQEEKIYCVGSPPI 899
Score = 67.8 bits (164), Expect = 2e-11
Identities = 99/450 (22%), Positives = 192/450 (42%), Gaps = 63/450 (14%)
Query: 20 HSMLEEL--ENKLIHSRKTERAKIQQQLAKIHNNV-----KKLQHQLKDVKPT------P 66
H M+ E +NKL ++K Q +A + KK+ H T P
Sbjct: 10 HPMMSEKTRQNKLAEAKKKFTDYRQWNIAGVGTGATDTKKKKINHGTNPETTTSGGCHSP 69
Query: 67 DFVEKLREMMEEIENAINTFKEEQRLIYE---ELIKEEKTTNNELSAI-------SRKID 116
+ ++ R ++E + A + +E R E I+ EL +RK +
Sbjct: 70 EDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFE 129
Query: 117 TWALG-----NSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYD 171
LG N +AFR P+ V+ S +P E D L + G
Sbjct: 130 DGNLGTPSSFNLALSQAFRGS----PLGCVSTSLIPGESKDLAGRLHHSWHFAGELQ--- 182
Query: 172 HQNFVKVRNKHKGKPTFMEEVLEHLPGK---------TQDEVQQHEKWYQKFLALEERKK 222
+ V +HK ++EE+ + T +E+++ Q+ L L E +K
Sbjct: 183 -RALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEK 241
Query: 223 ESIQIWKTKKQQKREEI-FKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQ---------K 272
IQ+ + ++K E F L + NT +QE+ +++E++ +KQ +
Sbjct: 242 SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER 301
Query: 273 LAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFL 332
L + K ++ E + +L+E+E++ ++ +KE + Q K L E Q ++++E+
Sbjct: 302 LREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ---KELREQEEQMQEQEEKMW 358
Query: 333 RLEKEIREKAEK---AEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAK 389
E+++RE+ EK E+R ++ R QE+ + E ++ ++ + EK ++ R K
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 418
Query: 390 LKEKVENNVSRDPSRLYKPTKGWEERTKKI 419
+ E+VE R+ ++ + K ++ +K+
Sbjct: 419 MWEQVEK--MREEKKMQEQEKKTRDQEEKM 446
Score = 67.8 bits (164), Expect = 2e-11
Identities = 62/340 (18%), Positives = 161/340 (47%), Gaps = 40/340 (11%)
Query: 81 NAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDK 140
+A++T ++ EEL KE A+S ++ + N E +K + K+P+ +
Sbjct: 186 SAVSTRHKKADRYIEELTKER-------DALSLELYRNTITNEELKKKNAELQEKLPLAE 238
Query: 141 VTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKT 200
S + V + ++ L++ F+ P L+ +
Sbjct: 239 SEKSEIQLNVKELKRKLERA-------------KFLL--------PQVQTNTLQEEMWRQ 277
Query: 201 QDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDN 260
++E+++ EK +K R++E ++ + K +++ E++++ +++ +QE
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRL--------REQEKE 329
Query: 261 QKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLES 320
+++E++ ++QK E ++++ E K Q ++ E+E+K ++ +R ++ + +
Sbjct: 330 LREQEKELREQKELRE--QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 387
Query: 321 YTQQKKEQEEFL-RLEKEIREKAEKAEKRKNAADEISRF-QERDLHKLELKILDRQAKED 378
Q+ ++QEE + ++ +REK E+ +++ +++ + +E+ + + E K D++ K
Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Query: 379 EKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKK 418
E+ + + R K++E+ E ++ + WE+ K+
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Score = 67.4 bits (163), Expect = 3e-11
Identities = 78/397 (19%), Positives = 184/397 (46%), Gaps = 64/397 (16%)
Query: 35 KTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIY 94
K + A++Q++L + ++Q +K++K +E+ + ++ +++ NT +EE
Sbjct: 224 KKKNAELQEKLPLAESEKSEIQLNVKELKRK---LERAKFLLPQVQT--NTLQEEMWRQE 278
Query: 95 EELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFE 154
EEL ++EK + EK +R E
Sbjct: 279 EELREQEKKIRKQ-----------------EEKMWRQ----------------------E 299
Query: 155 KFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEK---WY 211
+ L++ G+ ++ + ++R + K +E+ E + Q+E Q ++ W
Sbjct: 300 ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWE 359
Query: 212 QKFLALEERKK---ESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQR 268
Q+ E+ +K + ++W+ +KQ + +E K++++ + +Q++ ++KEE+
Sbjct: 360 QEEKMREQEEKMWRQEERLWEQEKQMREQE-QKMRDQEERM-----WEQDERLREKEERM 413
Query: 269 KKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQ----- 323
++Q+ E +K + + + + +++EEK ++ ++ R+R+ K++ E+ +
Sbjct: 414 REQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKM 473
Query: 324 QKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQK 383
QK+E+ + + EKE +++ +K K E + QE + + E KI D++ ++ +K
Sbjct: 474 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE-KK 532
Query: 384 QRRLAKLKEKVENNVSRDPSRLYKPTKGW--EERTKK 418
R K++E+ + ++ + K W EER +K
Sbjct: 533 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEK 569
Score = 65.1 bits (157), Expect = 1e-10
Identities = 79/436 (18%), Positives = 197/436 (45%), Gaps = 46/436 (10%)
Query: 2 EKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKD 61
E++K + +K E + E E K+ +T R + ++++ K N+ + + +
Sbjct: 434 EQEKKTRDQEEKMQ---EEERIREREKKMREEEETMREQ-EEKMQKQEENMWEQEEKEWQ 489
Query: 62 VKPTPDFVEKLREMMEEIENAINTFKEEQRLI-YEELIKEEKTTNNELSAISRKIDTWAL 120
+ P+ EKL E + E +++E+++ EE+ +EK + ++ W
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW-- 547
Query: 121 GNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRN 180
E E+ R K + ++ EK Q+ + WD + +
Sbjct: 548 ---EQEEKMRDQEQK----------MWDQEERMEKKTQEQ--EKKTWDQEEKMREEERMR 592
Query: 181 KHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQ-IWKTKKQ--QKRE 237
+ + K EE++ K Q++ ++ ++ +K EE+ +E + +W+ +++ ++ E
Sbjct: 593 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652
Query: 238 EIFKLKEKADNTPVLF-HNKQEDNQKQKEEQ----------RKKQKLAVEAWKKQKSIEM 286
++++ + + L+ H K ++ +K +E++ +K Q+ + W ++K E
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE 712
Query: 287 -SMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKA 345
SM+ + EEE+ + Q+E+ ++ + K+ ++++EE E+++ E+ EK
Sbjct: 713 ESMREREKKMREEEEMMREQEEKMQEQEEKM--------QEQEEEMWEQEEKMWEQEEKM 764
Query: 346 EKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQR-RLAKLKEKVENNVSRDPSR 404
+++ ++ + E + + + KI +++ K ++ +K R + K++ + E ++
Sbjct: 765 WEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKM 824
Query: 405 LYKPTKGWEERTKKIG 420
+ K W + K G
Sbjct: 825 WGQEEKMWGQEEKMWG 840
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 77.8 bits (190), Expect = 2e-14
Identities = 95/404 (23%), Positives = 177/404 (43%), Gaps = 58/404 (14%)
Query: 87 KEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKV--TPS 144
K + EL +E+ + EL K + S+ + R V +++ TP+
Sbjct: 450 KRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPT 509
Query: 145 TLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEV 204
+ P V+ + F+++ + + + Q +R K + + ++V E + ++
Sbjct: 510 SAPRSVM--KSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVK 567
Query: 205 QQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQK 264
+ E+ +K L ER ++ + K + +QK +I + EKA + E+ K+K
Sbjct: 568 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLA-----EEKAKKK 622
Query: 265 EEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEE------EKEKKHQKERQRQF-KLKLL 317
+K ++ VEA +KQ+ ++ Q +EE +K+K+ ++ER R+ + K L
Sbjct: 623 AAAKKMEE--VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRL 680
Query: 318 LESYTQQKKEQE--EFLRLEKEIREKAEKAEKRKNAADEISRFQER-----------DLH 364
E Q+++EQE E R E+E RE+ + ++R+ A E R QER
Sbjct: 681 AEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKAL 740
Query: 365 KLELKILDRQAKEDEKSQKQRRLA--KLKEKVEN----------------NVSRDPSRLY 406
+L+ + L R+ +E +K ++Q+RLA +L+E+ E +V Y
Sbjct: 741 RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSY 800
Query: 407 KPTKGWEERTKKIGPTGSGPLLHI---------PHRAIPTWRQG 441
+ T KI P G L+ P + IPTW +G
Sbjct: 801 QMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRKPIPTWARG 844
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 76.6 bits (187), Expect = 4e-14
Identities = 78/388 (20%), Positives = 187/388 (48%), Gaps = 49/388 (12%)
Query: 16 FRIEHSMLEELENKLIHSRKTERAKIQ--QQLAKIHNNVKKLQHQLKDVKPTPDFVEKLR 73
FR E +L+E E + +H ++ +R ++ QQL + + K + +L+ +P F+E+ +
Sbjct: 1463 FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQ 1522
Query: 74 EMMEEIENAINTFKEEQRLIYEELIKEEKTTNN----ELSAISRKIDTWALGNSETEKAF 129
++ + + +EEQ+L +E ++ + + E + ++ + L E ++ F
Sbjct: 1523 QLHRQ-QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF 1581
Query: 130 RAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFM 189
R + KV + ++ E+ L++ G+Q + D + F
Sbjct: 1582 R-----LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK--------------FR 1622
Query: 190 EEVLEHLPGKTQDEVQQHEKWYQKFLALEE--RKKESIQIWKTKKQQKREEIFKLKEKAD 247
E+ E L + +++ ++ +KFL E R++E Q + + +K E +L ++ +
Sbjct: 1623 ED--EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE 1680
Query: 248 NTPVLFHNK----QEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKK 303
+ + +E+ Q+ + ++R+++ L E +++ +E + QL++E E+E+
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Query: 304 HQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDL 363
++ER R K+L E + ++E+++ R E++ + + E+ + QER+
Sbjct: 1741 RRQERYR----KILEEEQLRPEREEQQLRRQERDRKFREEEQLR-----------QEREE 1785
Query: 364 HKLELKILDRQAKEDEKSQKQRRLAKLK 391
+L + DR+ +E+E+ +++R +L+
Sbjct: 1786 QQLRSQESDRKFREEEQLRQEREEQQLR 1813
Score = 74.7 bits (182), Expect = 2e-13
Identities = 85/393 (21%), Positives = 179/393 (45%), Gaps = 24/393 (6%)
Query: 12 QKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEK 71
Q+ D R +LE + R+ +R + +++LA+ +K + + + D E+
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD--EE 172
Query: 72 LREMMEEIENAINTFKEEQRLIY------EELIKEEKTTNNELSAISRKIDTWALGNSET 125
L +E + EE++L EE EE+ EL + RK G E
Sbjct: 173 LWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRK------GREEK 226
Query: 126 EKAFRAISSKVPVDKVTPSTLPEEVL---DFEKFLQQTGGRQGAWDDYDHQNFVKVRNKH 182
++ R +V ++ E + + EK ++ RQ + + Q R +
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 183 KGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKL 242
+ + E+ + L + Q +Q E+ ++ E+++ Q + ++QQ R E +
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER 346
Query: 243 KEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEK 302
+E+ +++ ++++EE+R++Q+L E +Q E ++ QL+ E++ +
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRRE---QQLRREQQLRREQQLRREQQLRR 403
Query: 303 KHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAA--DEISRFQE 360
+ Q R++Q + + L Q ++EQEE +K +E+ E+ KR+ D + R +E
Sbjct: 404 EQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEE 463
Query: 361 RDLHKLELKILDRQAKEDEKSQKQRRLAKLKEK 393
+ H+ E + +Q K D++ +++ R KL+E+
Sbjct: 464 TERHEQERR--KQQLKRDQEEERRERWLKLEEE 494
Score = 72.8 bits (177), Expect = 6e-13
Identities = 94/434 (21%), Positives = 209/434 (48%), Gaps = 35/434 (8%)
Query: 2 EKDKHSHFYNQKSDF--RIEHSMLEELENKLIHSRKTERAKIQQQLAK----IHNNVKKL 55
E++K F ++ R L+E E+ L ++ R++ Q++ K + K+
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
Query: 56 QHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEE--LIKEEKTTNNELSAISR 113
+H L + + K +++++E E + + E+R E+ +EE+ E + R
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945
Query: 114 KIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQ 173
+ + E E+ +R + + L EE EK +Q ++ ++ Q
Sbjct: 946 E-EREKRRRQERERQYRKDKK---LQQKEEQLLGEEP---EKRRRQEREKKYREEEELQQ 998
Query: 174 NFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQ 233
++ + + K E ++ + +DE+QQ E+ L EER+K +Q + ++
Sbjct: 999 EEEQLLREEREKRRRQEWERQY---RKKDELQQEEEQ----LLREEREKRRLQE-RERQY 1050
Query: 234 QKREEIFKLKEKADNTPVLFHNKQE-DNQKQKEE--QRKKQKLAVEAWKKQKSIEMSMKC 290
++ EE+ + +E+ +QE + Q +KEE Q+++++L E +K++ E +C
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110
Query: 291 ASQ--LKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKR 348
+ L++EEE+ + ++E++R+ +L+ + ++E+E+ LR E E R + E E++
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE-LERQ 1169
Query: 349 KNAADEISRFQERDLHKLELKIL---DRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRL 405
+E+ + +E+ L + + K +RQ +E+E+ Q+Q+R + +++ + + D
Sbjct: 1170 YREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS---DLKWQ 1226
Query: 406 YKPTKGWEERTKKI 419
++P K R K+
Sbjct: 1227 WEPEKENAVRDNKV 1240
Score = 69.3 bits (168), Expect = 7e-12
Identities = 46/229 (20%), Positives = 126/229 (55%), Gaps = 12/229 (5%)
Query: 190 EEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNT 249
EE L+ + Q E+Q+ E+ +K L +E ++E + + +++ +RE+ + K++ +
Sbjct: 257 EEKLQEEEPQRQRELQEEEEQLRK-LERQELRRERQEEEQQQQRLRREQQLRRKQEEERR 315
Query: 250 PVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQ 309
+++ +++++E+R++Q+L E ++++ QL+ E+E+E++ Q+ R+
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQ---------QLRREQEEERREQQLRR 366
Query: 310 RQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELK 369
Q + + + +Q+ +E+ LR E+++R + + +++ ++ R +++ + +L+
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 370 ILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKK 418
+ + ++K +++RR +LK + E RD + + T+ E+ +K
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEER--RDWLKREEETERHEQERRK 473
Score = 68.6 bits (166), Expect = 1e-11
Identities = 77/423 (18%), Positives = 195/423 (46%), Gaps = 36/423 (8%)
Query: 12 QKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEK 71
++ + + E L +LE + + + E + QQ+L + +K + + ++ + ++
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 72 LREMMEEI-ENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFR 130
RE EE E + +EE+R E+ ++ E+ + R+ E E+ +
Sbjct: 327 RREQQEERREQQLRREQEERR---EQQLRREQEEERREQQLRRE--------QEEERREQ 375
Query: 131 AISSKVPVDKVTPSTLPEEVLDFEKFL---QQTGGRQGAWDDYDHQNFVKVRNKHKGKPT 187
+ + + + E+ L E+ L QQ Q + + ++R + + +
Sbjct: 376 QLRREQQLRR-EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Query: 188 FMEEVLEHLPGKTQDEVQQHEKWYQKFLALE--ERKKESIQIWKTKKQQKREEIFKLKEK 245
+ E + + E ++ W ++ E E+++ Q+ + +++++RE KL+E+
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494
Query: 246 ADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEE------ 299
++E ++++E+R++Q+L + ++++ ++ ++ QL+ E+E
Sbjct: 495 ERREQ---QERREQQLRREQEERREQRLKRQ--EEEERLQQRLRSEQQLRREQEERREQL 549
Query: 300 ---KEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEIS 356
+E+K ++ +R+ +LK E Q ++EE R ++ RE+ E+ E+R +E+
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK-REEVE 608
Query: 357 RFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERT 416
R ++ + + LK R+ E+E+ Q+ + + +E+ + + R+ + EE
Sbjct: 609 RLEQEERREQRLK---REEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 417 KKI 419
+++
Sbjct: 666 ERL 668
Score = 68.6 bits (166), Expect = 1e-11
Identities = 91/427 (21%), Positives = 196/427 (45%), Gaps = 38/427 (8%)
Query: 2 EKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKD 61
E+++ Q+ + E LEE E ++ ERA QQL + + +++ Q + +
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQL----QRRERA---QQLQEEEDGLQEDQERRRS 865
Query: 62 VKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALG 121
+ D +K R +EE + + E+L KE++ E + R+
Sbjct: 866 QEQRRD--QKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE------- 916
Query: 122 NSETEKAFRAISSKVPVDKVTPSTLPEEVL--DFEKFLQQTGGRQGAWDDYDHQNFVKVR 179
E EK R + ++ E++L + EK +Q RQ D Q ++
Sbjct: 917 --EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974
Query: 180 NKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKT---KKQQKR 236
+ K E ++ + ++E+QQ E+ L EER+K Q W+ KK + +
Sbjct: 975 GEEPEKRRRQEREKKY---REEEELQQEEEQ----LLREEREKRRRQEWERQYRKKDELQ 1027
Query: 237 EEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEA-WKKQKSIEMSMKCASQLK 295
+E +L + L +++ ++++ +Q ++Q L E ++++ +E + +L+
Sbjct: 1028 QEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
Query: 296 EEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEI 355
+EEE+ + + E++R+ + + + ++E+E+ LR E+E R + E E++ +E+
Sbjct: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE-LERQYREEEEV 1146
Query: 356 SRFQERDL----HKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKG 411
+ +E+ L K + L+RQ +E+E+ Q++ +E+ + R+ R Y+ +
Sbjct: 1147 QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERE--RQYREEEE 1204
Query: 412 WEERTKK 418
+ + +K
Sbjct: 1205 LQRQKRK 1211
Score = 65.9 bits (159), Expect = 7e-11
Identities = 55/233 (23%), Positives = 119/233 (51%), Gaps = 44/233 (18%)
Query: 190 EEVLEHLPGKTQDEV--QQHEKWYQKFLALEERKKESIQIWKTK----------KQQKRE 237
+E LE + +DE +Q ++W ++ EER+ E Q+ K +Q +R
Sbjct: 158 QERLEQRDRQRRDEELWRQRQEWQER----EERRAEEEQLQSCKGHETEEFPDEEQLRRR 213
Query: 238 EIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEE 297
E+ +L+ K +++ Q+++ + R Q+ + W+K++++ L++E
Sbjct: 214 ELLELRRKG--------REEKQQQRRERQDRVFQEEEEKEWRKRETV---------LRKE 256
Query: 298 EEKEKKHQKERQRQF-----KLKLL----LESYTQQKKEQEEFLRLEKEIREKAEKAEKR 348
EEK ++ + +RQR+ +L+ L L Q++++Q++ LR E+++R K E E+R
Sbjct: 257 EEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE--EER 314
Query: 349 KNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRD 401
+ +E QER + E + + +++E+ ++Q R + +E+ E + R+
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
Score = 62.8 bits (151), Expect = 6e-10
Identities = 80/447 (17%), Positives = 201/447 (44%), Gaps = 44/447 (9%)
Query: 1 MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQ-- 58
+E+++ ++ + R + + E E + ++ + +++Q+L + V++L+ +
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR--EEVERLEQEER 615
Query: 59 ----LKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRK 114
LK +P + ++L + E+ E + EQ+ E+ +K E+ + R+
Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675
Query: 115 IDT----WALGNSETEKAFRAISSKVPVDK--VTPSTLPEEVLDFEKFLQQTGGRQGAWD 168
+ L E E+A I S++P + + + + + +Q G R+
Sbjct: 676 HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR---- 731
Query: 169 DYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDE----------VQQHEKWYQKFLALE 218
Q + R + + + + EE H + +++ ++ E+ Q+ A
Sbjct: 732 ---RQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Query: 219 ERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQ---KEEQRKKQKLAV 275
+++ + + +++Q+RE+ F L E+ + ++ + + Q +EEQ ++++ A
Sbjct: 789 PLREQRERQLRAEERQQREQRF-LPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQ 847
Query: 276 EAWKKQKSI-EMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRL 334
+ +++ + E + SQ + ++K + +E +++ + L + Q++ +E+ L
Sbjct: 848 QLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907
Query: 335 EKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQ---AKEDEKSQKQRRLAKLK 391
E+E + E+ EKR+ E +E L + E ++L + + E+ ++ R+ KL+
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
Query: 392 EKVENNVSRDPSRLYKPTKGWEERTKK 418
+K E + +P + + +ER KK
Sbjct: 968 QKEEQLLGEEPEKRRR-----QEREKK 989
Score = 60.5 bits (145), Expect = 3e-09
Identities = 81/440 (18%), Positives = 195/440 (44%), Gaps = 33/440 (7%)
Query: 2 EKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKD 61
E+++ H + + R + E+ E + R+ E + +Q+ K +K+ Q + +
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK--QQLKRDQEEERR 485
Query: 62 VKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALG 121
+ E+ RE E E + +EE+R E+ +K ++ E + +++ +
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERR---EQRLKRQE----EEERLQQRLRSEQQL 538
Query: 122 NSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNK 181
E E+ R K +K E+ L E+ ++ + ++ Q +K +
Sbjct: 539 RREQEER-REQLLKREEEKRLEQERREQRLKREQ--EERRDQLLKREEERRQQRLKREQE 595
Query: 182 HKGKPTFMEEVLEHLPGKTQDEV-----QQHEKWYQKFLALEERKKESIQIWKTKKQQKR 236
+ + E +E L + + E + E+ Q+ L EE+++ Q + ++Q++R
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 237 EEIFKLKEKADNTPVLFHNKQEDNQKQKE-------EQRKKQKLAVEAWKKQKSIE---- 285
E+ K +E+ + + E+ ++++E + R++ K + W+ Q E
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR 715
Query: 286 MSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYT-----QQKKEQEEFLRLEKEIRE 340
S + K+E ++ ++ Q+E++R+ + +L + QQ++EQ + + E
Sbjct: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEE 775
Query: 341 KAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSR 400
K+E+ +R +A + +ER L E + +++ +E+ ++QRR + + + E
Sbjct: 776 KSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE 835
Query: 401 DPSRLYKPTKGWEERTKKIG 420
+ +L + + + + ++ G
Sbjct: 836 EEEQLQRRERAQQLQEEEDG 855
Score = 56.2 bits (134), Expect = 6e-08
Identities = 88/418 (21%), Positives = 187/418 (44%), Gaps = 39/418 (9%)
Query: 17 RIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLR--- 73
R E + +E E L R+ R + ++ + V++ + QL +P ++L
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 74 ----EMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAI-----SRKIDTWALGNSE 124
E+ +E E + +E++R E +EE+ + ++ D E
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPE 1230
Query: 125 TEKAFR--AISSKVPVDKVTPSTLPEEVLD--FEKFLQQTGGRQGAWDDYDHQNFVKVRN 180
E A R + K ++ ++ D ++ LQ G Q D + + R+
Sbjct: 1231 KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
Query: 181 KHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKK-ESIQIWKTKKQ--QKRE 237
+H + +E E K +D Q EK + E+R++ E+ + ++ ++Q Q+RE
Sbjct: 1291 RHFPEEEQLERE-EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE 1349
Query: 238 EIFKLKEKADNT---PVLFHNKQ-----EDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMK 289
E +++ D L H +Q E+ Q+ + ++R+++ L E + + E ++
Sbjct: 1350 EQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR 1409
Query: 290 CASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRK 349
K EE+++ ++ER R+F+ + E ++++ + +FL E+++R+ E+ K +
Sbjct: 1410 QDRDRKFREEEQQLSRQERDRKFREE---EQQVRRQERERKFLEEEQQLRQ--ERHRKFR 1464
Query: 350 NAADEISRFQERDLHKLELKILDRQAKEDEKS-QKQRRLAKLKEKVENNVSRDPSRLY 406
+ +E+ LH+ E DR+ E+E+ ++Q R K +E + S++P R +
Sbjct: 1465 EEEQLLQEREEQQLHRQE---RDRKFLEEEQQLRRQERDRKFRE--QELRSQEPERKF 1517
Score = 55.8 bits (133), Expect = 8e-08
Identities = 95/456 (20%), Positives = 197/456 (43%), Gaps = 102/456 (22%)
Query: 12 QKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEK 71
Q+ +R E + +E E L R+ R + +++ + +++ + QL +P EK
Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEP-----EK 980
Query: 72 LREMMEEIENAINTFKEEQRLIYEE--LIKEE--KTTNNELSAISRKIDTWALGNSETEK 127
R E ++EE+ L EE L++EE K E RK D E E+
Sbjct: 981 RRRQERE-----KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL---QQEEEQ 1032
Query: 128 AFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPT 187
R K + + EE L E+ +Q G + + T
Sbjct: 1033 LLREEREKRRLQERERQYREEEELQQEE--EQLLGEE--------------------RET 1070
Query: 188 FMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKAD 247
+ LE K ++E+QQ E+ + + R++E + + +++ ++EE L+E+ +
Sbjct: 1071 RRRQELERQYRK-EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE 1129
Query: 248 NTPVLFHNKQEDNQKQKEE----QRKKQKLAVEAWKKQK-SIEMSMKCASQLKEEE---- 298
+QE ++ +EE Q ++Q L E K+++ +E + +L++EE
Sbjct: 1130 K-----RRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184
Query: 299 -EKEKKHQKERQRQFKLKLLLESYTQQK-------------------------------- 325
E+++K ++ER+RQ++ + L+ +++
Sbjct: 1185 REEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKG 1244
Query: 326 KEQEEFLRLE-KEIREKAEK--------AEKRKNAADEISRFQERDLHKLELKILDRQ-- 374
+E E+F +LE ++R++ + ++ ++ E R+Q+RD H E + L+R+
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 375 ---AKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYK 407
+ D KSQ++++L + +E+ E ++ R ++
Sbjct: 1305 KEAKRRDRKSQEEKQLLR-EEREEKRRRQETDRKFR 1339
Score = 55.5 bits (132), Expect = 1e-07
Identities = 79/390 (20%), Positives = 174/390 (44%), Gaps = 52/390 (13%)
Query: 19 EHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQH---QLKDVKPTPDFVEKLREM 75
E+ +LE+ + R++++ +Q L + ++ + Q +D + P+ + RE
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQ-DLQHLLGEQQERDREQERRRWQQRD-RHFPEEEQLEREE 1303
Query: 76 MEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSK 135
+E + +EE++L+ EE +EEK E T++ FR
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREE--REEKRRRQE-----------------TDRKFREEEQL 1344
Query: 136 VPVDKVTPSTLPEEVLDF--EKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVL 193
+ + P E F E+ Q GR+ ++ ++R + + + EE
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQ------RLRRQERERKFLKEEQQ 1398
Query: 194 EHLPGKTQDEVQQHEKWY---QKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTP 250
+ Q Q ++ + ++ L+ +ER ++ + + ++Q+RE F +E+
Sbjct: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ----- 1453
Query: 251 VLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQR 310
+QE ++K +EE++ Q+ + +Q+ ++ QL+ +E K ++E +
Sbjct: 1454 ---QLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510
Query: 311 QFKLKLLLESYTQ--QKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLEL 368
Q + LE Q +++ Q +FL+ E+++R + E+ ++R+ D R +E+ + E
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLR-RQERGQQRRQDRDRKFREEEQLRQEREE 1569
Query: 369 KILDRQAK------EDEKSQKQRRLAKLKE 392
+ L RQ + E++K ++Q + K E
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFME 1599
Score = 53.9 bits (128), Expect = 3e-07
Identities = 49/243 (20%), Positives = 119/243 (48%), Gaps = 12/243 (4%)
Query: 181 KHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIF 240
+ KG+ ++ E Q+E ++ + + L EE K + + + ++ Q+ EE
Sbjct: 219 RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 241 KLKEKADNTPVLFHNKQEDNQKQ---KEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEE 297
+ E+ + L +QE+ Q+Q + EQ+ ++K E ++Q+ + Q +E
Sbjct: 279 RKLERQE----LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 298 EEKE-KKHQKERQRQFKLKLLLESYTQQ--KKEQEEFLRLEKEIREKAEKAEKRKNAADE 354
E++ ++ Q+ER+ Q + E +Q ++EQEE R ++ RE+ + E++ +
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
Query: 355 ISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEE 414
+ R E+ L + + ++Q + +++ +++++L + +E+ + + R + K +E
Sbjct: 395 LRR--EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
Query: 415 RTK 417
+
Sbjct: 453 ERR 455
Score = 51.6 bits (122), Expect = 1e-06
Identities = 47/192 (24%), Positives = 101/192 (52%), Gaps = 12/192 (6%)
Query: 188 FMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERK--KESIQIWKTKKQQKREEIFKLKEK 245
F EE E L +T+ E + ++ Y+K L E+ + +E Q+ + ++ +K E +L+++
Sbjct: 1725 FREE--EQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE 1782
Query: 246 ADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQ 305
+ + QE ++K +EE++ +Q+ + + Q+ + + + + EE+E++ +
Sbjct: 1783 REEQQL---RSQESDRKFREEEQLRQEREEQQLRPQQR-DGKYRWEEEQLQLEEQEQRLR 1838
Query: 306 KERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQ-ERDLH 364
+ER RQ++ + + TQ+K +EE L +E +K + +RK + I R Q E H
Sbjct: 1839 QERDRQYRAEE--QFATQEKSRREE-QELWQEEEQKRRQERERKLREEHIRRQQKEEQRH 1895
Query: 365 KLELKILDRQAK 376
+ +I ++ K
Sbjct: 1896 RQVGEIKSQEGK 1907
Score = 50.8 bits (120), Expect = 2e-06
Identities = 82/416 (19%), Positives = 174/416 (41%), Gaps = 55/416 (13%)
Query: 12 QKSDFRIEHSMLEELENKLIHSR-KTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVE 70
++ +R E + +E E L R K R + ++Q K ++ + L++ + E
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045
Query: 71 KLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWA-----LGNSET 125
+ R+ EE E +EE++L+ EE E EL RK + L E
Sbjct: 1046 RERQYREEEELQ----QEEEQLLGEE---RETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Query: 126 EKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGK 185
EK R + ++ E++L E+ ++ RQ Y + V+
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRR---RQELERQYREEEEVQQEE----- 1150
Query: 186 PTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEK 245
E++L P K + Q+ E+ Y++ L++ +++ ++ + K++Q+RE ++ +E+
Sbjct: 1151 ----EQLLREEPEKRRR--QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEE 1204
Query: 246 ADNTPVLFHNKQEDNQ----------------------KQKEEQRKKQKLAVEAWKKQKS 283
+ ED + K +E ++ +Q + +Q
Sbjct: 1205 LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQ 1264
Query: 284 IEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAE 343
++ Q + + E+E++ ++R R F + LE Q++ ++ + E++ + E
Sbjct: 1265 QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324
Query: 344 KAEKRKNA------ADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEK 393
+ EKR+ +E QER+ L + DR+ +E+E +++ L+E+
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Score = 48.5 bits (114), Expect = 1e-05
Identities = 41/220 (18%), Positives = 110/220 (50%), Gaps = 30/220 (13%)
Query: 199 KTQDEVQQHEKWYQKFLALEER------------KKESIQIWKTKKQQKREEIFKLKEKA 246
K ++E +H++ +KFL E+R +++ ++ + ++Q +++ K +E+
Sbjct: 1361 KFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420
Query: 247 DNTPVLFHNKQEDNQKQKEE------QRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK 300
++QE ++K +EE Q +++K E + ++ + QL +E E+
Sbjct: 1421 QQL-----SRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE 1475
Query: 301 EKKHQKERQRQF-KLKLLLESYTQQKKEQEEFLRLEK------EIREKAEKAEKRKNAAD 353
++ H++ER R+F + + L + +K +E+ LR ++ E ++ + ++++
Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQ 1535
Query: 354 EISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEK 393
E + + ++ + + DR+ +E+E+ +++R +L +
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ 1575
Score = 46.6 bits (109), Expect = 5e-05
Identities = 35/145 (24%), Positives = 81/145 (55%), Gaps = 8/145 (5%)
Query: 251 VLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQR 310
+L +QE++Q++ E + ++ + ++QK E + A ++ E++E+ Q++RQR
Sbjct: 109 LLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR 168
Query: 311 QFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKI 370
+ + E + Q+++ QE R +E + ++ K + + DE + + R+L LEL+
Sbjct: 169 RDE-----ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE-EQLRRREL--LELRR 220
Query: 371 LDRQAKEDEKSQKQRRLAKLKEKVE 395
R+ K+ ++ ++Q R+ + +E+ E
Sbjct: 221 KGREEKQQQRRERQDRVFQEEEEKE 245
Score = 45.1 bits (105), Expect = 1e-04
Identities = 61/341 (17%), Positives = 152/341 (44%), Gaps = 58/341 (17%)
Query: 16 FRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREM 75
FR + +L+E E + +H ++ +R ++++ +L+ Q ++ + D K RE
Sbjct: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEE--------PQLRRQEREQQLRHDRDRKFREE 1672
Query: 76 MEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKI----DTWALGNSETEKAFRA 131
+ ++ EEQ+L +E ++ + +L R+ + L E E+ FR
Sbjct: 1673 EQLLQEG-----EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR- 1726
Query: 132 ISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEE 191
+ E+ Q+T Q +R + + + EE
Sbjct: 1727 --------------------EEEQLRQETEQEQ-------------LRRQERYRKILEEE 1753
Query: 192 VLEHLPGKTQDEVQQHE---KWYQKFLALEERKKESIQIWKT-KKQQKREEIFKLKEKAD 247
L P + + ++++ E K+ ++ +ER+++ ++ ++ +K ++ E++ + +E+
Sbjct: 1754 QLR--PEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811
Query: 248 NTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKE 307
P K ++Q + + ++Q+L E +Q E + + EE++ + +++
Sbjct: 1812 LRPQQRDGKYRWEEEQLQLEEQEQRLRQER-DRQYRAEEQFATQEKSRREEQELWQEEEQ 1870
Query: 308 RQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKR 348
++RQ + + L E + ++++++E+ R EI+ + K R
Sbjct: 1871 KRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGR 1911
Score = 39.7 bits (91), Expect = 0.006
Identities = 58/277 (20%), Positives = 119/277 (42%), Gaps = 57/277 (20%)
Query: 10 YNQKSDFRIEHSMLEELENKLIHSRKTERA--KIQQQLAKIHNNVKKLQH--QLKDVKPT 65
+++ FR E +L+E E + + ++ +R + +QQL + K LQ QL+ +
Sbjct: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE 1722
Query: 66 PDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSET 125
F E+ + E + + + ++++ EE ++ E+ L E
Sbjct: 1723 RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQ-------------LRRQER 1769
Query: 126 EKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHK-- 183
++ FR EE L E+ QQ ++ + + + R + +
Sbjct: 1770 DRKFRE----------------EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLR 1813
Query: 184 -----GKPTFMEEVLEHLPGKTQDEVQQHEKWY---QKFLALEERKKESIQIWKTKKQQK 235
GK + EE L+ L + Q Q+ ++ Y ++F E+ ++E ++W+ ++Q++
Sbjct: 1814 PQQRDGKYRWEEEQLQ-LEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKR 1872
Query: 236 REE-IFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQ 271
R+E KL+E + ++QKEEQR +Q
Sbjct: 1873 RQERERKLRE------------EHIRRQQKEEQRHRQ 1897
Score = 30.4 bits (67), Expect = 3.4
Identities = 18/80 (22%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
Query: 319 ESYTQQKKEQEEFLRLEKEIREKAE-----KAEKRKNAADEISRFQERDLHKLELKILDR 373
ES Q ++++E+ R E R+ E + +KR+ E++ +E+ + L+ DR
Sbjct: 107 ESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDR 166
Query: 374 QAKEDEKSQKQRRLAKLKEK 393
Q +++E ++++ + +E+
Sbjct: 167 QRRDEELWRQRQEWQEREER 186
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 75.9 bits (185), Expect = 7e-14
Identities = 97/393 (24%), Positives = 175/393 (44%), Gaps = 50/393 (12%)
Query: 12 QKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEK 71
Q RI ELE L +S+ R L + + +L H F +
Sbjct: 90 QDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWH-------FAGE 142
Query: 72 LREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRA 131
L+ + +A++T+ ++ EEL KE + EL + + N+E ++ R
Sbjct: 143 LQRAL----SAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRL 198
Query: 132 ISSKVPVDKVTPSTLPEEVLDFEKFL----QQTGGRQGAWDDYDH--QNFVKVRNKHKGK 185
S+ ++ L + L+ KFL Q ++ W + + K+R K + K
Sbjct: 199 AESEKSEIQLNVKELKRK-LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIR-KQEEK 256
Query: 186 PTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEK 245
EE L GK ++ Q EK ++ L E++KE + K ++QK KL+E+
Sbjct: 257 MWRQEERLREQEGKMRE---QEEKMRRQEKRLREQEKELREQEKELREQK-----KLREQ 308
Query: 246 ADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQ 305
+ E +K +E++ K + W+++K Q++E+E+K + Q
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK----------QMREQEQK-MRDQ 357
Query: 306 KER--QRQFKLKLLLESYTQQKK--EQEEFLRLEKEIREKAEKAEKRKNAADEISRFQER 361
+ER ++ +L+ E +Q+K EQEE ++ E+ IRE+ EK+ +E R QE
Sbjct: 358 EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER----EKKMREEEETMREQEE 413
Query: 362 DLHKLELKILDRQAKEDEKSQKQRRLAKLKEKV 394
+ K E + +++EK +Q+RL + KEK+
Sbjct: 414 KMQKQE----ENMWEQEEKEWQQQRLPEQKEKL 442
Score = 75.5 bits (184), Expect = 9e-14
Identities = 77/418 (18%), Positives = 193/418 (46%), Gaps = 32/418 (7%)
Query: 3 KDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDV 62
+D+ + Q R + + E E + E+ + Q+ +I KK++ + + +
Sbjct: 355 RDQEERMWEQDERLREKEERMREQE------KMWEQEEKMQEEERIREREKKMREEEETM 408
Query: 63 KPTPDFVEKLREMM---EEIENAINTFKEEQRLIYEE--LIKEEKTTNNELSAISRKIDT 117
+ + ++K E M EE E E++ ++E+ + ++E+ + I + +
Sbjct: 409 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
Query: 118 WALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVK 177
W + +K +R + D++ E++ D E+ + R D+ + +
Sbjct: 469 WG----QEKKMWRQEKMREQEDQMWEQE--EKMRDQEQKMWDQEERMWEQDERLREKEER 522
Query: 178 VRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKF-LALEERKKESIQIWKTKKQQKR 236
+R + K M + E + + + + Q+ + W Q+ + EER +E + + +++ R
Sbjct: 523 MREQKK-----MWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 577
Query: 237 EEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKE 296
E+ K++E+ + E +K +E++ K + + W++++ +M + ++
Sbjct: 578 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ 637
Query: 297 EEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEK---AEKRKNAAD 353
EE+ +++ +K +++ K++ E + ++++E+ E+++RE+ EK E++ +
Sbjct: 638 EEKMQEQEEKMWEQEEKMR---EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE 694
Query: 354 EISRFQERDLHKLELKILDRQAK---EDEKSQKQRRLAKLKEKVENNVSRDPSRLYKP 408
E R QE + E K+ ++ K ++E +K+ R+ KEK++ + R +P
Sbjct: 695 EKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEP 752
Score = 71.2 bits (173), Expect = 2e-12
Identities = 81/426 (19%), Positives = 195/426 (45%), Gaps = 23/426 (5%)
Query: 12 QKSDFRIEHSMLEELENKLIHSRKTERA---KIQQQLAKIHNNVKKLQHQLKDVKPTPDF 68
++ R + ++E E K+ + R K+ +Q ++ K+++ Q + ++ +
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 69 V----EKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSE 124
+ E+LRE E + +++E+++ EE I+E + E R+ + E
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420
Query: 125 T-----EKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVR 179
EK ++ +K+ +E EK +Q + + + + + +
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQE--QEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
Query: 180 NKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLAL---EERKKESIQIWKTKKQQKR 236
K + + M E E + + Q Q E+ +++ L EER +E ++W+ +++ +
Sbjct: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
Query: 237 EEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKE 296
E+ K +E+ T +E+ + ++ E++ +++ + +++K E K Q ++
Sbjct: 539 EK--KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596
Query: 297 EEEKEKKHQKERQRQFKL-KLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEI 355
E+E+K Q++ ++ ++ + + E + K +++E + E+E EK ++ E++ +E
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE--EKMQEQEEKMWEQEEK 654
Query: 356 SRFQERDLHKLELKILDRQAKEDEKSQK-QRRLAKLKEKVENNVSRDPSRLYKPTKGWEE 414
R QE + + E K+ ++ K E+ +K Q + K++E+ E ++ + K W +
Sbjct: 655 MREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQ 714
Query: 415 RTKKIG 420
K G
Sbjct: 715 EEKMWG 720
Score = 69.7 bits (169), Expect = 5e-12
Identities = 56/222 (25%), Positives = 114/222 (51%), Gaps = 19/222 (8%)
Query: 200 TQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEI-FKLKEKADNTPVLFHNKQE 258
T +E+++ Q+ L L E +K IQ+ + ++K E F L + NT QE
Sbjct: 181 TNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNT------LQE 234
Query: 259 DNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLL 318
+ +Q+EE R+++K K +K E + +L+E+E K ++ +++ +RQ K L
Sbjct: 235 EMWRQEEELREQEK------KIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKR---L 285
Query: 319 ESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAA---DEISRFQERDLHKLELKILDRQA 375
++ +EQE+ LR +K++RE+ E+ ++++ +E R QE + + E ++ +++
Sbjct: 286 REQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 345
Query: 376 KEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTK 417
+ E+ QK R + + + + R+ + K WE+ K
Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEK 387
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 74.7 bits (182), Expect = 2e-13
Identities = 95/408 (23%), Positives = 179/408 (43%), Gaps = 62/408 (15%)
Query: 87 KEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKV--TPS 144
K + EL +E+ + EL K + S+ + R V +++ TP+
Sbjct: 450 KRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPT 509
Query: 145 TLPEEVLDFEKFLQQTG----GRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKT 200
+ P V+ + F+++ + ++ + + Q +R K + + ++V E +
Sbjct: 510 SAPRSVM--KSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRL 567
Query: 201 QDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDN 260
++ + E+ +K L ER ++ + K + +QK +I + EKA + E+
Sbjct: 568 EEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLA-----EEK 622
Query: 261 QKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEE------EKEKKHQKERQRQF-K 313
K+K +K ++ VEA +KQ+ ++ Q +EE +K+K+ ++ER R+ +
Sbjct: 623 AKKKAAAKKMEE--VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 680
Query: 314 LKLLLESYTQQKKEQE--EFLRLEKEIREKAEKAEKRKNAADEISRFQER---------- 361
K L E Q+++EQE E R E+E RE+ + ++R+ A E R QER
Sbjct: 681 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQER 740
Query: 362 -DLHKLELKILDRQAKEDEKSQKQRRLA--KLKEKVEN----------------NVSRDP 402
+L+ + L R+ +E +K ++Q+RLA +L+E+ E +V
Sbjct: 741 EKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPA 800
Query: 403 SRLYKPTKGWEERTKKIGPTGSGPLLHI---------PHRAIPTWRQG 441
Y+ T KI P G L+ P + IPTW +G
Sbjct: 801 CTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRKPIPTWARG 848
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 72.4 bits (176), Expect = 8e-13
Identities = 55/207 (26%), Positives = 110/207 (53%), Gaps = 8/207 (3%)
Query: 219 ERKKESIQIWKTKKQQKREEIFKL--KEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVE 276
ERKKE + K K+++++E + KEK ++E +K++E+QRK+++ E
Sbjct: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR---E 91
Query: 277 AWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEK 336
++++ E + Q E K+KK +KER+R+ K + + ++KK++ + + EK
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
Query: 337 EIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN 396
E ++ K +KRK E R + R K E + +R+ ++ E+ +K+RR K ++K
Sbjct: 152 ERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKER-KKERRKKKERKKDRK 210
Query: 397 NVSRDPSRLYKPTKGWEERTKKIGPTG 423
+ S++++P + E ++ TG
Sbjct: 211 TDRQTDSQVFRPLR--ESAFNRVTVTG 235
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/185 (23%), Positives = 91/185 (49%), Gaps = 23/185 (12%)
Query: 177 KVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKR 236
K R + +GK + + + + ++ EK ++ E RK++ + + +KQ+ R
Sbjct: 52 KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR 111
Query: 237 EEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKE 296
E K KE+ + ++ +N++++E +RKK++ KK++ K + +
Sbjct: 112 RERKKKKERKE--------RERENKQRRERKRKKRRK-----KKRRKERKREKERGKRER 158
Query: 297 EEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEIS 356
+ +K KK ++E++R+ K ++KKE+E R E+ R+K K E+RK +
Sbjct: 159 KRKKRKKEEREKKRERNRK-------ERKKERE---RKERRERKKERKKERRKKKERKKD 208
Query: 357 RFQER 361
R +R
Sbjct: 209 RKTDR 213
Score = 49.3 bits (116), Expect = 7e-06
Identities = 29/130 (22%), Positives = 71/130 (54%)
Query: 289 KCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKR 348
K +Q + E +KE++ +++R+R+ + + E ++KK++++ R ++ R++ E+ ++R
Sbjct: 27 KPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
Query: 349 KNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKP 408
K ++ R ++++ K E K R+ ++ +K +K+R + + R + K
Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
Query: 409 TKGWEERTKK 418
K +ER K+
Sbjct: 147 RKREKERGKR 156
Score = 45.1 bits (105), Expect = 1e-04
Identities = 37/159 (23%), Positives = 79/159 (49%), Gaps = 8/159 (5%)
Query: 177 KVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKR 236
K R K + + E K ++ Q+ + +K +ER++E+ K ++++KR
Sbjct: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKEREREN----KQRRERKR 135
Query: 237 EEIFKLKEKADNTPVLFHNKQE-DNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLK 295
++ K K + + K+E +K+K+E+R+K++ E +K++ E K + K
Sbjct: 136 KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR---ERNRKERKKERERKERRERK 192
Query: 296 EEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRL 334
+E +KE++ +KER++ K +S + + F R+
Sbjct: 193 KERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRV 231
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 70.9 bits (172), Expect = 2e-12
Identities = 55/201 (27%), Positives = 103/201 (51%), Gaps = 2/201 (0%)
Query: 219 ERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVE-A 277
+ K++ +Q K ++Q+ E+ +L++K + QE Q + E + +++ V A
Sbjct: 855 QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLA 914
Query: 278 WKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKE 337
KKQ+ E+ + ++L+EEE++ ++ Q ER++ + L LE ++++ + L+LEK
Sbjct: 915 AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV 974
Query: 338 IRE-KAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN 396
E K +K E D+ + ++ LE +I D E+ +K + L KLK K E+
Sbjct: 975 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1034
Query: 397 NVSRDPSRLYKPTKGWEERTK 417
+S RL K K +E K
Sbjct: 1035 MISELEVRLKKEEKSRQELEK 1055
Score = 62.0 bits (149), Expect = 1e-09
Identities = 100/467 (21%), Positives = 199/467 (42%), Gaps = 82/467 (17%)
Query: 12 QKSDFRIEHSMLEELENKL---IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDF 68
QK + + LEE N L + + +++ ++ ++ + + +L+D T +
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1389
Query: 69 VEK-LREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEK 127
+E+ + +EIEN + EE+ Y++L K + EL + +D S EK
Sbjct: 1390 LEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448
Query: 128 AFRA----------ISSKVPVDK--------------VTPSTLPEEVLDFEKFLQQTGGR 163
R ISSK ++ ++ + EE L+ ++ L++T
Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1508
Query: 164 QGAW--------DDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHE----KWY 211
A DD +N ++ + T MEE+ L + +DE+Q E +
Sbjct: 1509 LKAEMEDLVSSKDDVG-KNVHELEKSKRALETQMEEMKTQLE-ELEDELQATEDAKLRLE 1566
Query: 212 QKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQ 271
AL+ + + +Q + ++KR ++ + + + + E++RK++
Sbjct: 1567 VNMQALKGQFERDLQARDEQNEEKRRQL--------------QRQLHEYETELEDERKQR 1612
Query: 272 KLAVEAWKKQ----KSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKE 327
LA A KK K +E+ A + +EE K+ + + + + F+ +L +
Sbjct: 1613 ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL-----EDARAS 1667
Query: 328 QEEFLRLEKEIREKAEKAE------KRKNAADEISRFQERDLHKLEL------KILDRQA 375
++E KE +KA+ E + AA E +R ++ DL K EL + R A
Sbjct: 1668 RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR-KQADLEKEELAEELASSLSGRNA 1726
Query: 376 KEDEKSQKQRRLAKLKEKVE---NNVSRDPSRLYKPTKGWEERTKKI 419
+DEK + + R+A+L+E++E N+ R+ K T+ E+ + ++
Sbjct: 1727 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1773
Score = 54.7 bits (130), Expect = 2e-07
Identities = 82/398 (20%), Positives = 167/398 (41%), Gaps = 57/398 (14%)
Query: 31 IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEK-------LREMMEEIENAI 83
+ +++ E K +++ K N +K+L+ + + + +++ L EE+ +
Sbjct: 854 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 913
Query: 84 NTFKEEQRLIYEEL---IKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDK 140
K+E I E+ ++EE+ +L A +K+ L E + A K+ ++K
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 973
Query: 141 VTPST----LPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHL 196
VT L +E+L D QN NK + +EE + L
Sbjct: 974 VTAEAKIKKLEDEILVM-----------------DDQN-----NKLSKERKLLEERISDL 1011
Query: 197 PGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNK 256
+E ++ K K E +++ K+++ R+E+ KLK K + FH +
Sbjct: 1012 TTNLAEE-EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 257 QEDNQ------------KQKEEQRKKQKLAVEAWKKQKSIEMSMKC---ASQLKEEEEKE 301
D Q K++E Q +L E +K +++ + S L+E+ + E
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
Query: 302 KKHQKERQRQFK-LKLLLESYTQQKKEQEEFLRLEKEIREKAE-KAEKRKNAADEISRFQ 359
+ + + ++Q + L LE+ + ++ + ++E+R K E + K A DE +R
Sbjct: 1131 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1190
Query: 360 ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENN 397
E + ++ K QA E E +++ + + K ++ N
Sbjct: 1191 EAQVQEMRQK--HAQAVE-ELTEQLEQFKRAKANLDKN 1225
Score = 47.8 bits (112), Expect = 2e-05
Identities = 83/419 (19%), Positives = 174/419 (41%), Gaps = 59/419 (14%)
Query: 21 SMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQL-KDVKPTPDFVEKLREMMEEI 79
+ LEELE++L + TE AK++ ++ N++ L+ Q +D++ + E+ R ++
Sbjct: 1546 TQLEELEDEL---QATEDAKLRLEV-----NMQALKGQFERDLQARDEQNEEKRRQLQRQ 1597
Query: 80 ENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVD 139
+ T E++R +K +L + + D+ G E K R + +++
Sbjct: 1598 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK-- 1655
Query: 140 KVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKG--------------- 184
DF++ L+ + +N K ++
Sbjct: 1656 ------------DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR 1703
Query: 185 ------KPTFMEEVLEHLPGKT--QDEVQQHEK---WYQKFLALEERKKESIQIWKTKKQ 233
K EE+ L G+ QDE ++ E ++ L E+ E++ K
Sbjct: 1704 KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKAT 1763
Query: 234 QKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKK---QKLAVEAWKKQKSIEMSMKC 290
Q+ E++ +T + ++ ++Q +E R K + AV++ K + K
Sbjct: 1764 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1823
Query: 291 ASQLKEEEEKEKKHQKE-----RQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKA 345
A QL+E+ E+E + ++ +Q+ KLK +L ++K E++ ++ + ++
Sbjct: 1824 A-QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
Query: 346 EKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSR 404
+++ A+E S+ + KL+ + LD + +E ++ K K + N S PSR
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQ-RELDEATESNEAMGREVNALKSKLRRGNETSFVPSR 1940
Score = 42.4 bits (98), Expect = 9e-04
Identities = 70/400 (17%), Positives = 167/400 (41%), Gaps = 50/400 (12%)
Query: 7 SHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTP 66
+ Y + + R+ + ++ +++H + + + + ++ KK+ Q+ D++
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 959
Query: 67 DFVEKLRE--MMEEIENAINTFKEEQRLIY-----EELIKEEKTTNNELSAISRKIDTWA 119
+ E R+ +E++ K E ++ +L KE K +S ++ +
Sbjct: 960 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL---- 1015
Query: 120 LGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVR 179
E EKA K + + + + E L++ ++ Q K++
Sbjct: 1016 --AEEEEKAKNLTKLKNKHESM--------ISELEVRLKK--------EEKSRQELEKLK 1057
Query: 180 NKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEI 239
K +G + E + L + + Q K ++ A R + I QK +
Sbjct: 1058 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI-------AQKNNAL 1110
Query: 240 FKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEE 299
K++E + L QED ++ + K +K + ++ ++++ ++ L
Sbjct: 1111 KKIRELEGHISDL----QEDLDSERAARNKAEKQKRDLGEELEALKTELE--DTLDSTAT 1164
Query: 300 KEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLE-----KEIREKAEKAEKRKNAADE 354
+++ K Q LK L+ T+ + Q + +R + +E+ E+ E+ ++ K D+
Sbjct: 1165 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1224
Query: 355 ISRFQERDLHKL--ELKILDRQAKEDEKSQKQRRLAKLKE 392
+ E++ L EL++L QAK++ + +K++ A+++E
Sbjct: 1225 NKQTLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQE 1263
Score = 40.0 bits (92), Expect = 0.004
Identities = 38/154 (24%), Positives = 80/154 (51%), Gaps = 17/154 (11%)
Query: 278 WKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFK----LKLLLESYTQQKKEQ---EE 330
W+ ++ ++ Q +E + KE + QK ++RQ K LK L + ++Q +E+ +E
Sbjct: 835 WRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
Query: 331 FLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAK- 389
L+ E E+ +AE+ R A + E LH++E ++ + + + + +++++A+
Sbjct: 895 QLQAETELYAEAEEMRVRLAAK---KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951
Query: 390 ---LKEKV-ENNVSRDPSRLYKPTKGWEERTKKI 419
L+E++ E +R +L K T E + KK+
Sbjct: 952 MLDLEEQLEEEEAARQKLQLEKVTA--EAKIKKL 983
Score = 39.7 bits (91), Expect = 0.006
Identities = 98/489 (20%), Positives = 187/489 (38%), Gaps = 95/489 (19%)
Query: 7 SHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKK----------LQ 56
S F+ Q +D + + + L+ K + A++ ++A+ +N +KK LQ
Sbjct: 1065 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ 1124
Query: 57 HQL--------KDVKPTPDFVEKLREMMEEIENAINTF--------KEEQRLIYEELIKE 100
L K K D E+L + E+E+ +++ K EQ + + +
Sbjct: 1125 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALD 1184
Query: 101 EKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQT 160
E+T ++E + TE+ + +K +DK TL +E D L+
Sbjct: 1185 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK-NKQTLEKENADLAGELRVL 1243
Query: 161 GGRQGAWDDYDHQ----------------NFVKVRNKHKGKPTFMEEVLEHLPGKTQDEV 204
G A + +H+ + + R + K ++ +E + G +
Sbjct: 1244 GQ---AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1300
Query: 205 QQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQK 264
+ K + +L + +++ ++ + + +QK KL++ + L E+ + ++
Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
Query: 265 EEQR-----------KKQKL--------AVEAWKK--QKSIE-----MSMKCASQLKEEE 298
+R K+KL A+E KK QK IE K A+ K E+
Sbjct: 1361 NLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1420
Query: 299 EKEKKHQ-------------------KERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIR 339
K + Q +++QR+F +LL E K +E R E E R
Sbjct: 1421 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD-QLLAEEKNISSKYADERDRAEAEAR 1479
Query: 340 EKAEKAEKRKNAADEISRFQ---ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN 396
EK KA A +E + ER L+ ++ D + +D+ + L K K +E
Sbjct: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1539
Query: 397 NVSRDPSRL 405
+ ++L
Sbjct: 1540 QMEEMKTQL 1548
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 70.9 bits (172), Expect = 2e-12
Identities = 55/201 (27%), Positives = 103/201 (51%), Gaps = 2/201 (0%)
Query: 219 ERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVE-A 277
+ K++ +Q K ++Q+ E+ +L++K + QE Q + E + +++ V A
Sbjct: 862 QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLA 921
Query: 278 WKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKE 337
KKQ+ E+ + ++L+EEE++ ++ Q ER++ + L LE ++++ + L+LEK
Sbjct: 922 AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV 981
Query: 338 IRE-KAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN 396
E K +K E D+ + ++ LE +I D E+ +K + L KLK K E+
Sbjct: 982 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1041
Query: 397 NVSRDPSRLYKPTKGWEERTK 417
+S RL K K +E K
Sbjct: 1042 MISELEVRLKKEEKSRQELEK 1062
Score = 62.0 bits (149), Expect = 1e-09
Identities = 100/467 (21%), Positives = 199/467 (42%), Gaps = 82/467 (17%)
Query: 12 QKSDFRIEHSMLEELENKL---IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDF 68
QK + + LEE N L + + +++ ++ ++ + + +L+D T +
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1396
Query: 69 VEK-LREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEK 127
+E+ + +EIEN + EE+ Y++L K + EL + +D S EK
Sbjct: 1397 LEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455
Query: 128 AFRA----------ISSKVPVDK--------------VTPSTLPEEVLDFEKFLQQTGGR 163
R ISSK ++ ++ + EE L+ ++ L++T
Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1515
Query: 164 QGAW--------DDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHE----KWY 211
A DD +N ++ + T MEE+ L + +DE+Q E +
Sbjct: 1516 LKAEMEDLVSSKDDVG-KNVHELEKSKRALETQMEEMKTQLE-ELEDELQATEDAKLRLE 1573
Query: 212 QKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQ 271
AL+ + + +Q + ++KR ++ + + + + E++RK++
Sbjct: 1574 VNMQALKGQFERDLQARDEQNEEKRRQL--------------QRQLHEYETELEDERKQR 1619
Query: 272 KLAVEAWKKQ----KSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKE 327
LA A KK K +E+ A + +EE K+ + + + + F+ +L +
Sbjct: 1620 ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL-----EDARAS 1674
Query: 328 QEEFLRLEKEIREKAEKAE------KRKNAADEISRFQERDLHKLEL------KILDRQA 375
++E KE +KA+ E + AA E +R ++ DL K EL + R A
Sbjct: 1675 RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR-KQADLEKEELAEELASSLSGRNA 1733
Query: 376 KEDEKSQKQRRLAKLKEKVE---NNVSRDPSRLYKPTKGWEERTKKI 419
+DEK + + R+A+L+E++E N+ R+ K T+ E+ + ++
Sbjct: 1734 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1780
Score = 54.7 bits (130), Expect = 2e-07
Identities = 82/398 (20%), Positives = 167/398 (41%), Gaps = 57/398 (14%)
Query: 31 IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEK-------LREMMEEIENAI 83
+ +++ E K +++ K N +K+L+ + + + +++ L EE+ +
Sbjct: 861 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 920
Query: 84 NTFKEEQRLIYEEL---IKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDK 140
K+E I E+ ++EE+ +L A +K+ L E + A K+ ++K
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 980
Query: 141 VTPST----LPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHL 196
VT L +E+L D QN NK + +EE + L
Sbjct: 981 VTAEAKIKKLEDEILVM-----------------DDQN-----NKLSKERKLLEERISDL 1018
Query: 197 PGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNK 256
+E ++ K K E +++ K+++ R+E+ KLK K + FH +
Sbjct: 1019 TTNLAEE-EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 257 QEDNQ------------KQKEEQRKKQKLAVEAWKKQKSIEMSMKC---ASQLKEEEEKE 301
D Q K++E Q +L E +K +++ + S L+E+ + E
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 302 KKHQKERQRQFK-LKLLLESYTQQKKEQEEFLRLEKEIREKAE-KAEKRKNAADEISRFQ 359
+ + + ++Q + L LE+ + ++ + ++E+R K E + K A DE +R
Sbjct: 1138 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1197
Query: 360 ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENN 397
E + ++ K QA E E +++ + + K ++ N
Sbjct: 1198 EAQVQEMRQK--HAQAVE-ELTEQLEQFKRAKANLDKN 1232
Score = 47.8 bits (112), Expect = 2e-05
Identities = 83/419 (19%), Positives = 174/419 (41%), Gaps = 59/419 (14%)
Query: 21 SMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQL-KDVKPTPDFVEKLREMMEEI 79
+ LEELE++L + TE AK++ ++ N++ L+ Q +D++ + E+ R ++
Sbjct: 1553 TQLEELEDEL---QATEDAKLRLEV-----NMQALKGQFERDLQARDEQNEEKRRQLQRQ 1604
Query: 80 ENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVD 139
+ T E++R +K +L + + D+ G E K R + +++
Sbjct: 1605 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK-- 1662
Query: 140 KVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKG--------------- 184
DF++ L+ + +N K ++
Sbjct: 1663 ------------DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR 1710
Query: 185 ------KPTFMEEVLEHLPGKT--QDEVQQHEK---WYQKFLALEERKKESIQIWKTKKQ 233
K EE+ L G+ QDE ++ E ++ L E+ E++ K
Sbjct: 1711 KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKAT 1770
Query: 234 QKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKK---QKLAVEAWKKQKSIEMSMKC 290
Q+ E++ +T + ++ ++Q +E R K + AV++ K + K
Sbjct: 1771 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1830
Query: 291 ASQLKEEEEKEKKHQKE-----RQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKA 345
A QL+E+ E+E + ++ +Q+ KLK +L ++K E++ ++ + ++
Sbjct: 1831 A-QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1889
Query: 346 EKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSR 404
+++ A+E S+ + KL+ + LD + +E ++ K K + N S PSR
Sbjct: 1890 KRQLEEAEEESQRINANRRKLQ-RELDEATESNEAMGREVNALKSKLRRGNETSFVPSR 1947
Score = 42.4 bits (98), Expect = 9e-04
Identities = 70/400 (17%), Positives = 167/400 (41%), Gaps = 50/400 (12%)
Query: 7 SHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTP 66
+ Y + + R+ + ++ +++H + + + + ++ KK+ Q+ D++
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 966
Query: 67 DFVEKLRE--MMEEIENAINTFKEEQRLIY-----EELIKEEKTTNNELSAISRKIDTWA 119
+ E R+ +E++ K E ++ +L KE K +S ++ +
Sbjct: 967 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL---- 1022
Query: 120 LGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVR 179
E EKA K + + + + E L++ ++ Q K++
Sbjct: 1023 --AEEEEKAKNLTKLKNKHESM--------ISELEVRLKK--------EEKSRQELEKLK 1064
Query: 180 NKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEI 239
K +G + E + L + + Q K ++ A R + I QK +
Sbjct: 1065 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI-------AQKNNAL 1117
Query: 240 FKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEE 299
K++E + L QED ++ + K +K + ++ ++++ ++ L
Sbjct: 1118 KKIRELEGHISDL----QEDLDSERAARNKAEKQKRDLGEELEALKTELE--DTLDSTAT 1171
Query: 300 KEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLE-----KEIREKAEKAEKRKNAADE 354
+++ K Q LK L+ T+ + Q + +R + +E+ E+ E+ ++ K D+
Sbjct: 1172 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1231
Query: 355 ISRFQERDLHKL--ELKILDRQAKEDEKSQKQRRLAKLKE 392
+ E++ L EL++L QAK++ + +K++ A+++E
Sbjct: 1232 NKQTLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQE 1270
Score = 40.0 bits (92), Expect = 0.004
Identities = 38/154 (24%), Positives = 80/154 (51%), Gaps = 17/154 (11%)
Query: 278 WKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFK----LKLLLESYTQQKKEQ---EE 330
W+ ++ ++ Q +E + KE + QK ++RQ K LK L + ++Q +E+ +E
Sbjct: 842 WRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 901
Query: 331 FLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAK- 389
L+ E E+ +AE+ R A + E LH++E ++ + + + + +++++A+
Sbjct: 902 QLQAETELYAEAEEMRVRLAAK---KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958
Query: 390 ---LKEKV-ENNVSRDPSRLYKPTKGWEERTKKI 419
L+E++ E +R +L K T E + KK+
Sbjct: 959 MLDLEEQLEEEEAARQKLQLEKVTA--EAKIKKL 990
Score = 39.7 bits (91), Expect = 0.006
Identities = 98/489 (20%), Positives = 187/489 (38%), Gaps = 95/489 (19%)
Query: 7 SHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKK----------LQ 56
S F+ Q +D + + + L+ K + A++ ++A+ +N +KK LQ
Sbjct: 1072 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ 1131
Query: 57 HQL--------KDVKPTPDFVEKLREMMEEIENAINTF--------KEEQRLIYEELIKE 100
L K K D E+L + E+E+ +++ K EQ + + +
Sbjct: 1132 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALD 1191
Query: 101 EKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQT 160
E+T ++E + TE+ + +K +DK TL +E D L+
Sbjct: 1192 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK-NKQTLEKENADLAGELRVL 1250
Query: 161 GGRQGAWDDYDHQ----------------NFVKVRNKHKGKPTFMEEVLEHLPGKTQDEV 204
G A + +H+ + + R + K ++ +E + G +
Sbjct: 1251 GQ---AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1307
Query: 205 QQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQK 264
+ K + +L + +++ ++ + + +QK KL++ + L E+ + ++
Sbjct: 1308 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367
Query: 265 EEQR-----------KKQKL--------AVEAWKK--QKSIE-----MSMKCASQLKEEE 298
+R K+KL A+E KK QK IE K A+ K E+
Sbjct: 1368 NLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1427
Query: 299 EKEKKHQ-------------------KERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIR 339
K + Q +++QR+F +LL E K +E R E E R
Sbjct: 1428 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD-QLLAEEKNISSKYADERDRAEAEAR 1486
Query: 340 EKAEKAEKRKNAADEISRFQ---ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN 396
EK KA A +E + ER L+ ++ D + +D+ + L K K +E
Sbjct: 1487 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1546
Query: 397 NVSRDPSRL 405
+ ++L
Sbjct: 1547 QMEEMKTQL 1555
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 70.9 bits (172), Expect = 2e-12
Identities = 55/201 (27%), Positives = 103/201 (51%), Gaps = 2/201 (0%)
Query: 219 ERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVE-A 277
+ K++ +Q K ++Q+ E+ +L++K + QE Q + E + +++ V A
Sbjct: 862 QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLA 921
Query: 278 WKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKE 337
KKQ+ E+ + ++L+EEE++ ++ Q ER++ + L LE ++++ + L+LEK
Sbjct: 922 AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV 981
Query: 338 IRE-KAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN 396
E K +K E D+ + ++ LE +I D E+ +K + L KLK K E+
Sbjct: 982 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1041
Query: 397 NVSRDPSRLYKPTKGWEERTK 417
+S RL K K +E K
Sbjct: 1042 MISELEVRLKKEEKSRQELEK 1062
Score = 62.0 bits (149), Expect = 1e-09
Identities = 100/467 (21%), Positives = 199/467 (42%), Gaps = 82/467 (17%)
Query: 12 QKSDFRIEHSMLEELENKL---IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDF 68
QK + + LEE N L + + +++ ++ ++ + + +L+D T +
Sbjct: 1337 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1396
Query: 69 VEK-LREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEK 127
+E+ + +EIEN + EE+ Y++L K + EL + +D S EK
Sbjct: 1397 LEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455
Query: 128 AFRA----------ISSKVPVDK--------------VTPSTLPEEVLDFEKFLQQTGGR 163
R ISSK ++ ++ + EE L+ ++ L++T
Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1515
Query: 164 QGAW--------DDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHE----KWY 211
A DD +N ++ + T MEE+ L + +DE+Q E +
Sbjct: 1516 LKAEMEDLVSSKDDVG-KNVHELEKSKRALETQMEEMKTQLE-ELEDELQATEDAKLRLE 1573
Query: 212 QKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQ 271
AL+ + + +Q + ++KR ++ + + + + E++RK++
Sbjct: 1574 VNMQALKGQFERDLQARDEQNEEKRRQL--------------QRQLHEYETELEDERKQR 1619
Query: 272 KLAVEAWKKQ----KSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKE 327
LA A KK K +E+ A + +EE K+ + + + + F+ +L +
Sbjct: 1620 ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL-----EDARAS 1674
Query: 328 QEEFLRLEKEIREKAEKAE------KRKNAADEISRFQERDLHKLEL------KILDRQA 375
++E KE +KA+ E + AA E +R ++ DL K EL + R A
Sbjct: 1675 RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR-KQADLEKEELAEELASSLSGRNA 1733
Query: 376 KEDEKSQKQRRLAKLKEKVE---NNVSRDPSRLYKPTKGWEERTKKI 419
+DEK + + R+A+L+E++E N+ R+ K T+ E+ + ++
Sbjct: 1734 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1780
Score = 54.7 bits (130), Expect = 2e-07
Identities = 82/398 (20%), Positives = 167/398 (41%), Gaps = 57/398 (14%)
Query: 31 IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEK-------LREMMEEIENAI 83
+ +++ E K +++ K N +K+L+ + + + +++ L EE+ +
Sbjct: 861 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 920
Query: 84 NTFKEEQRLIYEEL---IKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDK 140
K+E I E+ ++EE+ +L A +K+ L E + A K+ ++K
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 980
Query: 141 VTPST----LPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHL 196
VT L +E+L D QN NK + +EE + L
Sbjct: 981 VTAEAKIKKLEDEILVM-----------------DDQN-----NKLSKERKLLEERISDL 1018
Query: 197 PGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNK 256
+E ++ K K E +++ K+++ R+E+ KLK K + FH +
Sbjct: 1019 TTNLAEE-EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1077
Query: 257 QEDNQ------------KQKEEQRKKQKLAVEAWKKQKSIEMSMKC---ASQLKEEEEKE 301
D Q K++E Q +L E +K +++ + S L+E+ + E
Sbjct: 1078 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 302 KKHQKERQRQFK-LKLLLESYTQQKKEQEEFLRLEKEIREKAE-KAEKRKNAADEISRFQ 359
+ + + ++Q + L LE+ + ++ + ++E+R K E + K A DE +R
Sbjct: 1138 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1197
Query: 360 ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENN 397
E + ++ K QA E E +++ + + K ++ N
Sbjct: 1198 EAQVQEMRQK--HAQAVE-ELTEQLEQFKRAKANLDKN 1232
Score = 42.4 bits (98), Expect = 9e-04
Identities = 70/400 (17%), Positives = 167/400 (41%), Gaps = 50/400 (12%)
Query: 7 SHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTP 66
+ Y + + R+ + ++ +++H + + + + ++ KK+ Q+ D++
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 966
Query: 67 DFVEKLRE--MMEEIENAINTFKEEQRLIY-----EELIKEEKTTNNELSAISRKIDTWA 119
+ E R+ +E++ K E ++ +L KE K +S ++ +
Sbjct: 967 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL---- 1022
Query: 120 LGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVR 179
E EKA K + + + + E L++ ++ Q K++
Sbjct: 1023 --AEEEEKAKNLTKLKNKHESM--------ISELEVRLKK--------EEKSRQELEKLK 1064
Query: 180 NKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEI 239
K +G + E + L + + Q K ++ A R + I QK +
Sbjct: 1065 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI-------AQKNNAL 1117
Query: 240 FKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEE 299
K++E + L QED ++ + K +K + ++ ++++ ++ L
Sbjct: 1118 KKIRELEGHISDL----QEDLDSERAARNKAEKQKRDLGEELEALKTELE--DTLDSTAT 1171
Query: 300 KEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLE-----KEIREKAEKAEKRKNAADE 354
+++ K Q LK L+ T+ + Q + +R + +E+ E+ E+ ++ K D+
Sbjct: 1172 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1231
Query: 355 ISRFQERDLHKL--ELKILDRQAKEDEKSQKQRRLAKLKE 392
+ E++ L EL++L QAK++ + +K++ A+++E
Sbjct: 1232 NKQTLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQE 1270
Score = 42.4 bits (98), Expect = 9e-04
Identities = 78/406 (19%), Positives = 168/406 (41%), Gaps = 59/406 (14%)
Query: 21 SMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQL-KDVKPTPDFVEKLREMMEEI 79
+ LEELE++L + TE AK++ ++ N++ L+ Q +D++ + E+ R ++
Sbjct: 1553 TQLEELEDEL---QATEDAKLRLEV-----NMQALKGQFERDLQARDEQNEEKRRQLQRQ 1604
Query: 80 ENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVD 139
+ T E++R +K +L + + D+ G E K R + +++
Sbjct: 1605 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK-- 1662
Query: 140 KVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKG--------------- 184
DF++ L+ + +N K ++
Sbjct: 1663 ------------DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR 1710
Query: 185 ------KPTFMEEVLEHLPGKT--QDEVQQHEK---WYQKFLALEERKKESIQIWKTKKQ 233
K EE+ L G+ QDE ++ E ++ L E+ E++ K
Sbjct: 1711 KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKAT 1770
Query: 234 QKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKK---QKLAVEAWKKQKSIEMSMKC 290
Q+ E++ +T + ++ ++Q +E R K + AV++ K + K
Sbjct: 1771 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1830
Query: 291 ASQLKEEEEKEKKHQKE-----RQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKA 345
A QL+E+ E+E + ++ +Q+ KLK +L ++K E++ ++ + ++
Sbjct: 1831 A-QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1889
Query: 346 EKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLK 391
+++ A+E S+ + KL+ + LD + +E ++ K K
Sbjct: 1890 KRQLEEAEEESQRINANRRKLQ-RELDEATESNEAMGREVNALKSK 1934
Score = 40.0 bits (92), Expect = 0.004
Identities = 38/154 (24%), Positives = 80/154 (51%), Gaps = 17/154 (11%)
Query: 278 WKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFK----LKLLLESYTQQKKEQ---EE 330
W+ ++ ++ Q +E + KE + QK ++RQ K LK L + ++Q +E+ +E
Sbjct: 842 WRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 901
Query: 331 FLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAK- 389
L+ E E+ +AE+ R A + E LH++E ++ + + + + +++++A+
Sbjct: 902 QLQAETELYAEAEEMRVRLAAK---KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958
Query: 390 ---LKEKV-ENNVSRDPSRLYKPTKGWEERTKKI 419
L+E++ E +R +L K T E + KK+
Sbjct: 959 MLDLEEQLEEEEAARQKLQLEKVTA--EAKIKKL 990
Score = 39.7 bits (91), Expect = 0.006
Identities = 98/489 (20%), Positives = 187/489 (38%), Gaps = 95/489 (19%)
Query: 7 SHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKK----------LQ 56
S F+ Q +D + + + L+ K + A++ ++A+ +N +KK LQ
Sbjct: 1072 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ 1131
Query: 57 HQL--------KDVKPTPDFVEKLREMMEEIENAINTF--------KEEQRLIYEELIKE 100
L K K D E+L + E+E+ +++ K EQ + + +
Sbjct: 1132 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALD 1191
Query: 101 EKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQT 160
E+T ++E + TE+ + +K +DK TL +E D L+
Sbjct: 1192 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK-NKQTLEKENADLAGELRVL 1250
Query: 161 GGRQGAWDDYDHQ----------------NFVKVRNKHKGKPTFMEEVLEHLPGKTQDEV 204
G A + +H+ + + R + K ++ +E + G +
Sbjct: 1251 GQ---AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1307
Query: 205 QQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQK 264
+ K + +L + +++ ++ + + +QK KL++ + L E+ + ++
Sbjct: 1308 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367
Query: 265 EEQR-----------KKQKL--------AVEAWKK--QKSIE-----MSMKCASQLKEEE 298
+R K+KL A+E KK QK IE K A+ K E+
Sbjct: 1368 NLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1427
Query: 299 EKEKKHQ-------------------KERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIR 339
K + Q +++QR+F +LL E K +E R E E R
Sbjct: 1428 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD-QLLAEEKNISSKYADERDRAEAEAR 1486
Query: 340 EKAEKAEKRKNAADEISRFQ---ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN 396
EK KA A +E + ER L+ ++ D + +D+ + L K K +E
Sbjct: 1487 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1546
Query: 397 NVSRDPSRL 405
+ ++L
Sbjct: 1547 QMEEMKTQL 1555
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 70.9 bits (172), Expect = 2e-12
Identities = 55/201 (27%), Positives = 103/201 (51%), Gaps = 2/201 (0%)
Query: 219 ERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVE-A 277
+ K++ +Q K ++Q+ E+ +L++K + QE Q + E + +++ V A
Sbjct: 855 QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLA 914
Query: 278 WKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKE 337
KKQ+ E+ + ++L+EEE++ ++ Q ER++ + L LE ++++ + L+LEK
Sbjct: 915 AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV 974
Query: 338 IRE-KAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN 396
E K +K E D+ + ++ LE +I D E+ +K + L KLK K E+
Sbjct: 975 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1034
Query: 397 NVSRDPSRLYKPTKGWEERTK 417
+S RL K K +E K
Sbjct: 1035 MISELEVRLKKEEKSRQELEK 1055
Score = 62.0 bits (149), Expect = 1e-09
Identities = 100/467 (21%), Positives = 199/467 (42%), Gaps = 82/467 (17%)
Query: 12 QKSDFRIEHSMLEELENKL---IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDF 68
QK + + LEE N L + + +++ ++ ++ + + +L+D T +
Sbjct: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1389
Query: 69 VEK-LREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEK 127
+E+ + +EIEN + EE+ Y++L K + EL + +D S EK
Sbjct: 1390 LEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448
Query: 128 AFRA----------ISSKVPVDK--------------VTPSTLPEEVLDFEKFLQQTGGR 163
R ISSK ++ ++ + EE L+ ++ L++T
Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1508
Query: 164 QGAW--------DDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHE----KWY 211
A DD +N ++ + T MEE+ L + +DE+Q E +
Sbjct: 1509 LKAEMEDLVSSKDDVG-KNVHELEKSKRALETQMEEMKTQLE-ELEDELQATEDAKLRLE 1566
Query: 212 QKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQ 271
AL+ + + +Q + ++KR ++ + + + + E++RK++
Sbjct: 1567 VNMQALKGQFERDLQARDEQNEEKRRQL--------------QRQLHEYETELEDERKQR 1612
Query: 272 KLAVEAWKKQ----KSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKE 327
LA A KK K +E+ A + +EE K+ + + + + F+ +L +
Sbjct: 1613 ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL-----EDARAS 1667
Query: 328 QEEFLRLEKEIREKAEKAE------KRKNAADEISRFQERDLHKLEL------KILDRQA 375
++E KE +KA+ E + AA E +R ++ DL K EL + R A
Sbjct: 1668 RDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR-KQADLEKEELAEELASSLSGRNA 1726
Query: 376 KEDEKSQKQRRLAKLKEKVE---NNVSRDPSRLYKPTKGWEERTKKI 419
+DEK + + R+A+L+E++E N+ R+ K T+ E+ + ++
Sbjct: 1727 LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNEL 1773
Score = 54.7 bits (130), Expect = 2e-07
Identities = 82/398 (20%), Positives = 167/398 (41%), Gaps = 57/398 (14%)
Query: 31 IHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEK-------LREMMEEIENAI 83
+ +++ E K +++ K N +K+L+ + + + +++ L EE+ +
Sbjct: 854 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 913
Query: 84 NTFKEEQRLIYEEL---IKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDK 140
K+E I E+ ++EE+ +L A +K+ L E + A K+ ++K
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 973
Query: 141 VTPST----LPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHL 196
VT L +E+L D QN NK + +EE + L
Sbjct: 974 VTAEAKIKKLEDEILVM-----------------DDQN-----NKLSKERKLLEERISDL 1011
Query: 197 PGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNK 256
+E ++ K K E +++ K+++ R+E+ KLK K + FH +
Sbjct: 1012 TTNLAEE-EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
Query: 257 QEDNQ------------KQKEEQRKKQKLAVEAWKKQKSIEMSMKC---ASQLKEEEEKE 301
D Q K++E Q +L E +K +++ + S L+E+ + E
Sbjct: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
Query: 302 KKHQKERQRQFK-LKLLLESYTQQKKEQEEFLRLEKEIREKAE-KAEKRKNAADEISRFQ 359
+ + + ++Q + L LE+ + ++ + ++E+R K E + K A DE +R
Sbjct: 1131 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1190
Query: 360 ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENN 397
E + ++ K QA E E +++ + + K ++ N
Sbjct: 1191 EAQVQEMRQK--HAQAVE-ELTEQLEQFKRAKANLDKN 1225
Score = 42.4 bits (98), Expect = 9e-04
Identities = 70/400 (17%), Positives = 167/400 (41%), Gaps = 50/400 (12%)
Query: 7 SHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTP 66
+ Y + + R+ + ++ +++H + + + + ++ KK+ Q+ D++
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 959
Query: 67 DFVEKLRE--MMEEIENAINTFKEEQRLIY-----EELIKEEKTTNNELSAISRKIDTWA 119
+ E R+ +E++ K E ++ +L KE K +S ++ +
Sbjct: 960 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL---- 1015
Query: 120 LGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVR 179
E EKA K + + + + E L++ ++ Q K++
Sbjct: 1016 --AEEEEKAKNLTKLKNKHESM--------ISELEVRLKK--------EEKSRQELEKLK 1057
Query: 180 NKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEI 239
K +G + E + L + + Q K ++ A R + I QK +
Sbjct: 1058 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI-------AQKNNAL 1110
Query: 240 FKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEE 299
K++E + L QED ++ + K +K + ++ ++++ ++ L
Sbjct: 1111 KKIRELEGHISDL----QEDLDSERAARNKAEKQKRDLGEELEALKTELE--DTLDSTAT 1164
Query: 300 KEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLE-----KEIREKAEKAEKRKNAADE 354
+++ K Q LK L+ T+ + Q + +R + +E+ E+ E+ ++ K D+
Sbjct: 1165 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1224
Query: 355 ISRFQERDLHKL--ELKILDRQAKEDEKSQKQRRLAKLKE 392
+ E++ L EL++L QAK++ + +K++ A+++E
Sbjct: 1225 NKQTLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQE 1263
Score = 42.4 bits (98), Expect = 9e-04
Identities = 78/406 (19%), Positives = 168/406 (41%), Gaps = 59/406 (14%)
Query: 21 SMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQL-KDVKPTPDFVEKLREMMEEI 79
+ LEELE++L + TE AK++ ++ N++ L+ Q +D++ + E+ R ++
Sbjct: 1546 TQLEELEDEL---QATEDAKLRLEV-----NMQALKGQFERDLQARDEQNEEKRRQLQRQ 1597
Query: 80 ENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVD 139
+ T E++R +K +L + + D+ G E K R + +++
Sbjct: 1598 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK-- 1655
Query: 140 KVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKG--------------- 184
DF++ L+ + +N K ++
Sbjct: 1656 ------------DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERAR 1703
Query: 185 ------KPTFMEEVLEHLPGKT--QDEVQQHEK---WYQKFLALEERKKESIQIWKTKKQ 233
K EE+ L G+ QDE ++ E ++ L E+ E++ K
Sbjct: 1704 KQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKAT 1763
Query: 234 QKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKK---QKLAVEAWKKQKSIEMSMKC 290
Q+ E++ +T + ++ ++Q +E R K + AV++ K + K
Sbjct: 1764 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 1823
Query: 291 ASQLKEEEEKEKKHQKE-----RQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKA 345
A QL+E+ E+E + ++ +Q+ KLK +L ++K E++ ++ + ++
Sbjct: 1824 A-QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
Query: 346 EKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLK 391
+++ A+E S+ + KL+ + LD + +E ++ K K
Sbjct: 1883 KRQLEEAEEESQRINANRRKLQ-RELDEATESNEAMGREVNALKSK 1927
Score = 40.0 bits (92), Expect = 0.004
Identities = 38/154 (24%), Positives = 80/154 (51%), Gaps = 17/154 (11%)
Query: 278 WKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFK----LKLLLESYTQQKKEQ---EE 330
W+ ++ ++ Q +E + KE + QK ++RQ K LK L + ++Q +E+ +E
Sbjct: 835 WRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
Query: 331 FLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAK- 389
L+ E E+ +AE+ R A + E LH++E ++ + + + + +++++A+
Sbjct: 895 QLQAETELYAEAEEMRVRLAAK---KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951
Query: 390 ---LKEKV-ENNVSRDPSRLYKPTKGWEERTKKI 419
L+E++ E +R +L K T E + KK+
Sbjct: 952 MLDLEEQLEEEEAARQKLQLEKVTA--EAKIKKL 983
Score = 39.7 bits (91), Expect = 0.006
Identities = 98/489 (20%), Positives = 187/489 (38%), Gaps = 95/489 (19%)
Query: 7 SHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKK----------LQ 56
S F+ Q +D + + + L+ K + A++ ++A+ +N +KK LQ
Sbjct: 1065 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ 1124
Query: 57 HQL--------KDVKPTPDFVEKLREMMEEIENAINTF--------KEEQRLIYEELIKE 100
L K K D E+L + E+E+ +++ K EQ + + +
Sbjct: 1125 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALD 1184
Query: 101 EKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQT 160
E+T ++E + TE+ + +K +DK TL +E D L+
Sbjct: 1185 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK-NKQTLEKENADLAGELRVL 1243
Query: 161 GGRQGAWDDYDHQ----------------NFVKVRNKHKGKPTFMEEVLEHLPGKTQDEV 204
G A + +H+ + + R + K ++ +E + G +
Sbjct: 1244 GQ---AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1300
Query: 205 QQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQK 264
+ K + +L + +++ ++ + + +QK KL++ + L E+ + ++
Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
Query: 265 EEQR-----------KKQKL--------AVEAWKK--QKSIE-----MSMKCASQLKEEE 298
+R K+KL A+E KK QK IE K A+ K E+
Sbjct: 1361 NLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1420
Query: 299 EKEKKHQ-------------------KERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIR 339
K + Q +++QR+F +LL E K +E R E E R
Sbjct: 1421 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD-QLLAEEKNISSKYADERDRAEAEAR 1479
Query: 340 EKAEKAEKRKNAADEISRFQ---ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN 396
EK KA A +E + ER L+ ++ D + +D+ + L K K +E
Sbjct: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALET 1539
Query: 397 NVSRDPSRL 405
+ ++L
Sbjct: 1540 QMEEMKTQL 1548
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 70.1 bits (170), Expect = 4e-12
Identities = 57/238 (23%), Positives = 123/238 (51%), Gaps = 17/238 (7%)
Query: 193 LEHLPGKTQDEVQQHEKWYQKFLALEE---RKKESIQIWKTKKQQKREEIFKLKEKADNT 249
L+ + K Q +V+++E W EE R++E IQ + K ++ +I + +EK
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 250 PVLFHNKQEDNQKQKEEQ-RKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK------EK 302
H ++E ++Q+++ R+++K+ + K ++ E + +++E++EK E
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 303 KHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAE---KAEKRKNAADEISRFQ 359
Q+E+ R+ + K + + Q+KK +E+ +++IRE+ E + E++ +E+ + Q
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQ----DEKIREQEEEMWRQEEKIRELEEMMQDQ 446
Query: 360 ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTK 417
E L ++E K+ + + K E+ +K +R + ++ E R L + K WE+ K
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEK 504
Score = 66.2 bits (160), Expect = 6e-11
Identities = 78/389 (20%), Positives = 178/389 (45%), Gaps = 64/389 (16%)
Query: 35 KTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIY 94
K + A++Q++L + + ++Q +KD+K ++E A ++Q +
Sbjct: 217 KEKNAELQEKLRLVESEKSEIQLNVKDLK-------------RKLERAQLLLPQQQLQVE 263
Query: 95 -EELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPV--DKVTPSTLP---- 147
+ L KE ++ + +L A + + W L N + E+ K+ +K+ L
Sbjct: 264 ADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQ 323
Query: 148 --------EEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGK 199
E++ + E+ +++ + ++ + K+R + + K EE + K
Sbjct: 324 EEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE-KMWRQEEKIREQDEK 382
Query: 200 TQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQ---------QKREEIFKLKEKADNTP 250
Q+ Q+ E W Q+ E+ +K ++W+ +K+ ++ EE+++ +EK
Sbjct: 383 IQE--QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 251 VLFHNKQED----NQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQK 306
+ +++E +K +EE+ K Q+ + ++++ I+ E+EEK + +K
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ----------EQEEKTWRQEK 490
Query: 307 ERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKL 366
+++ K + E + +++E+ E++++E+ EK +++ +E R QE L +
Sbjct: 491 LLKQEEK---IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ----EEKMREQEVRLWQQ 543
Query: 367 ELKILDRQAKEDEKSQKQRRLAKLKEKVE 395
E K+ Q +E + + RL KL +K E
Sbjct: 544 EEKM---QEQEVRLQELEERLGKLGQKAE 569
Score = 65.9 bits (159), Expect = 7e-11
Identities = 48/226 (21%), Positives = 114/226 (50%), Gaps = 10/226 (4%)
Query: 201 QDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDN 260
Q E + K Q A + + E ++W QQ+ E++++ +EK ++
Sbjct: 261 QVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKI 320
Query: 261 QKQKEEQ-RKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLE 319
++Q+E+ R+++K+ + K ++ + + +++E+EEK ++ +++ RQ + + E
Sbjct: 321 REQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK--IRE 378
Query: 320 SYTQQKKEQEEFLRLEKEIREKAEK-------AEKRKNAADEISRFQERDLHKLELKILD 372
+ ++++EE R E++IRE+ EK EK+ DE R QE ++ + E KI +
Sbjct: 379 QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 373 RQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKK 418
+ ++ +K R + + ++ E + ++ + + +E+ +K
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Score = 57.0 bits (136), Expect = 3e-08
Identities = 76/351 (21%), Positives = 156/351 (44%), Gaps = 49/351 (13%)
Query: 34 RKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIE--NAINTFKEEQR 91
RK ERA++ ++ +L +L+ V KL+ +EE E N +N +EE+
Sbjct: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSA------KLQAQVEENELWNLLNQQQEEKM 299
Query: 92 LIYEELIKE--EKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEE 149
EE I+E EK EL ++ W E+ K+ + E+
Sbjct: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMW-----RQEEKMHEQEEKIREQEDKMWRQEEK 354
Query: 150 VLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEK 209
+ + E+ +++ + ++ + K++ + + E++ E Q+E +Q +
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE------QEEKRQEKM 408
Query: 210 WYQKFLALEERKK---ESIQIWKTKKQ--------QKREEIFKLKEKADNTPVLFHNKQE 258
W Q+ E+ +K + ++W+ +++ Q +EE KL+E + QE
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE--KLREVEEKMQEEEEKMQE 466
Query: 259 DNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQ----LKEEE---EKEKKHQK----- 306
+K + ++ K Q+ + W+++K ++ K Q ++EE E+E+K Q+
Sbjct: 467 QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 307 ERQRQFKLKLLLESYTQQKKEQEEFLR---LEKEIREKAEKAEKRKNAADE 354
+RQ + + + + Q++K QE+ +R LE+ + + +KAE A E
Sbjct: 527 QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRE 577
Score = 55.5 bits (132), Expect = 1e-07
Identities = 55/218 (25%), Positives = 107/218 (49%), Gaps = 31/218 (14%)
Query: 200 TQDEVQQHEKWYQKFLALEERKKESIQ--IWKTKKQQKREEIF----KLKEKADNTPVLF 253
T +E+++ Q+ L L E +K IQ + K++ +R ++ +L+ +AD
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL 271
Query: 254 HNKQEDNQKQKEEQRK----KQKLAVEAWKKQKSIEMSMK--CASQLK--EEEEK----- 300
+ Q Q EE Q+ + W++++ I+ + C +LK E+EEK
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
Query: 301 EKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEK---AEKRKNAADEISR 357
EK H++E + + E + +++E+ E++IRE+ EK E++ DE +
Sbjct: 332 EKMHEQEEK-------IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 358 FQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVE 395
QE ++ + E KI +++ K EK +Q + K++E+ E
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEK--KMREQDE 420
Score = 38.5 bits (88), Expect = 0.012
Identities = 43/248 (17%), Positives = 103/248 (41%), Gaps = 44/248 (17%)
Query: 3 KDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDV 62
+++ + Q+ R + ++E E ++ + R + +++ K+ KK++ Q + +
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKI 422
Query: 63 KPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGN 122
+ + + + E + E+E + +E+ R + E++ +EE+ + I R+ +
Sbjct: 423 REQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI---Q 479
Query: 123 SETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKH 182
+ EK +R EK L+Q + W+ +
Sbjct: 480 EQEEKTWRQ----------------------EKLLKQ---EEKIWEQEE----------- 503
Query: 183 KGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEER---KKESIQIWKTKKQQKREEI 239
K EE + K Q++ ++ ++ +K E R ++E +Q + + Q+ E +
Sbjct: 504 --KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Query: 240 FKLKEKAD 247
KL +KA+
Sbjct: 562 GKLGQKAE 569
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 70.1 bits (170), Expect = 4e-12
Identities = 57/238 (23%), Positives = 123/238 (51%), Gaps = 17/238 (7%)
Query: 193 LEHLPGKTQDEVQQHEKWYQKFLALEE---RKKESIQIWKTKKQQKREEIFKLKEKADNT 249
L+ + K Q +V+++E W EE R++E IQ + K ++ +I + +EK
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 250 PVLFHNKQEDNQKQKEEQ-RKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK------EK 302
H ++E ++Q+++ R+++K+ + K ++ E + +++E++EK E
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 303 KHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAE---KAEKRKNAADEISRFQ 359
Q+E+ R+ + K + + Q+KK +E+ +++IRE+ E + E++ +E+ + Q
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQ----DEKIREQEEEMWRQEEKIRELEEMMQDQ 446
Query: 360 ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTK 417
E L ++E K+ + + K E+ +K +R + ++ E R L + K WE+ K
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEK 504
Score = 66.2 bits (160), Expect = 6e-11
Identities = 78/389 (20%), Positives = 178/389 (45%), Gaps = 64/389 (16%)
Query: 35 KTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIY 94
K + A++Q++L + + ++Q +KD+K ++E A ++Q +
Sbjct: 217 KEKNAELQEKLRLVESEKSEIQLNVKDLK-------------RKLERAQLLLPQQQLQVE 263
Query: 95 -EELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPV--DKVTPSTLP---- 147
+ L KE ++ + +L A + + W L N + E+ K+ +K+ L
Sbjct: 264 ADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQ 323
Query: 148 --------EEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGK 199
E++ + E+ +++ + ++ + K+R + + K EE + K
Sbjct: 324 EEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEE-KMWRQEEKIREQDEK 382
Query: 200 TQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQ---------QKREEIFKLKEKADNTP 250
Q+ Q+ E W Q+ E+ +K ++W+ +K+ ++ EE+++ +EK
Sbjct: 383 IQE--QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 251 VLFHNKQED----NQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQK 306
+ +++E +K +EE+ K Q+ + ++++ I+ E+EEK + +K
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ----------EQEEKTWRQEK 490
Query: 307 ERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKL 366
+++ K + E + +++E+ E++++E+ EK +++ +E R QE L +
Sbjct: 491 LLKQEEK---IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQ----EEKMREQEVRLWQQ 543
Query: 367 ELKILDRQAKEDEKSQKQRRLAKLKEKVE 395
E K+ Q +E + + RL KL +K E
Sbjct: 544 EEKM---QEQEVRLQELEERLGKLGQKAE 569
Score = 65.9 bits (159), Expect = 7e-11
Identities = 48/226 (21%), Positives = 114/226 (50%), Gaps = 10/226 (4%)
Query: 201 QDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDN 260
Q E + K Q A + + E ++W QQ+ E++++ +EK ++
Sbjct: 261 QVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKI 320
Query: 261 QKQKEEQ-RKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLE 319
++Q+E+ R+++K+ + K ++ + + +++E+EEK ++ +++ RQ + + E
Sbjct: 321 REQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEK--IRE 378
Query: 320 SYTQQKKEQEEFLRLEKEIREKAEK-------AEKRKNAADEISRFQERDLHKLELKILD 372
+ ++++EE R E++IRE+ EK EK+ DE R QE ++ + E KI +
Sbjct: 379 QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 373 RQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKK 418
+ ++ +K R + + ++ E + ++ + + +E+ +K
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Score = 57.0 bits (136), Expect = 3e-08
Identities = 76/351 (21%), Positives = 156/351 (44%), Gaps = 49/351 (13%)
Query: 34 RKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIE--NAINTFKEEQR 91
RK ERA++ ++ +L +L+ V KL+ +EE E N +N +EE+
Sbjct: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSA------KLQAQVEENELWNLLNQQQEEKM 299
Query: 92 LIYEELIKE--EKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEE 149
EE I+E EK EL ++ W E+ K+ + E+
Sbjct: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMW-----RQEEKMHEQEEKIREQEDKMWRQEEK 354
Query: 150 VLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEK 209
+ + E+ +++ + ++ + K++ + + E++ E Q+E +Q +
Sbjct: 355 IREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIRE------QEEKRQEKM 408
Query: 210 WYQKFLALEERKK---ESIQIWKTKKQ--------QKREEIFKLKEKADNTPVLFHNKQE 258
W Q+ E+ +K + ++W+ +++ Q +EE KL+E + QE
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE--KLREVEEKMQEEEEKMQE 466
Query: 259 DNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQ----LKEEE---EKEKKHQK----- 306
+K + ++ K Q+ + W+++K ++ K Q ++EE E+E+K Q+
Sbjct: 467 QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 307 ERQRQFKLKLLLESYTQQKKEQEEFLR---LEKEIREKAEKAEKRKNAADE 354
+RQ + + + + Q++K QE+ +R LE+ + + +KAE A E
Sbjct: 527 QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRE 577
Score = 55.5 bits (132), Expect = 1e-07
Identities = 55/218 (25%), Positives = 107/218 (49%), Gaps = 31/218 (14%)
Query: 200 TQDEVQQHEKWYQKFLALEERKKESIQ--IWKTKKQQKREEIF----KLKEKADNTPVLF 253
T +E+++ Q+ L L E +K IQ + K++ +R ++ +L+ +AD
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL 271
Query: 254 HNKQEDNQKQKEEQRK----KQKLAVEAWKKQKSIEMSMK--CASQLK--EEEEK----- 300
+ Q Q EE Q+ + W++++ I+ + C +LK E+EEK
Sbjct: 272 QSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQE 331
Query: 301 EKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEK---AEKRKNAADEISR 357
EK H++E + + E + +++E+ E++IRE+ EK E++ DE +
Sbjct: 332 EKMHEQEEK-------IREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 358 FQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVE 395
QE ++ + E KI +++ K EK +Q + K++E+ E
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEK--KMREQDE 420
Score = 38.5 bits (88), Expect = 0.012
Identities = 43/248 (17%), Positives = 103/248 (41%), Gaps = 44/248 (17%)
Query: 3 KDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDV 62
+++ + Q+ R + ++E E ++ + R + +++ K+ KK++ Q + +
Sbjct: 363 REQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKI 422
Query: 63 KPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGN 122
+ + + + E + E+E + +E+ R + E++ +EE+ + I R+ +
Sbjct: 423 REQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI---Q 479
Query: 123 SETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKH 182
+ EK +R EK L+Q + W+ +
Sbjct: 480 EQEEKTWRQ----------------------EKLLKQ---EEKIWEQEE----------- 503
Query: 183 KGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEER---KKESIQIWKTKKQQKREEI 239
K EE + K Q++ ++ ++ +K E R ++E +Q + + Q+ E +
Sbjct: 504 --KMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
Query: 240 FKLKEKAD 247
KL +KA+
Sbjct: 562 GKLGQKAE 569
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 69.7 bits (169), Expect = 5e-12
Identities = 110/450 (24%), Positives = 188/450 (41%), Gaps = 80/450 (17%)
Query: 37 ERAKIQQQLAKIHNNVKKLQHQLKD-VKPTPDFVEKLREMMEEIENAINTFKEEQRLIYE 95
E+A++ Q L + NN LQ + ++ D +KL + EEI N +++++L+
Sbjct: 2481 EKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLV-- 2538
Query: 96 ELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEK 155
++LS + + W N E + K+ V + ++L ++ L+ +
Sbjct: 2539 ----------SKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASL-QDTLEVLQ 2587
Query: 156 FLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFL 215
+ + D +FV+ NK K T ++ + + KT E+Q+ + L
Sbjct: 2588 SSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTA-ELQEELSGEKNRL 2646
Query: 216 A------LEERKKESIQIWKT--------------------KKQQKREEIFKLK------ 243
A LEE K Q+ + K+ + REEI + +
Sbjct: 2647 AGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEA 2706
Query: 244 EKADNTPVLFHNKQEDNQKQ--------KEEQRKKQKLAVEAWKKQKS-IEMSMKCASQL 294
EK +L NKQ + + Q KEE QKL ++ K K + S+K +Q+
Sbjct: 2707 EKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQI 2766
Query: 295 KEEEEKEKKH--------QKERQR-QFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKA 345
EE +K K +KE +R Q K+KLL++S Q ++E+E L+KE+ +
Sbjct: 2767 LEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKE---ILQKELSQLQAAQ 2823
Query: 346 EKRKNAADEISRFQERDLHKLELK-ILDRQAKE-DEKSQK-------QRRLAKLKEKVEN 396
EK+K ++ E ELK L+ + KE DE K +L K KE +E
Sbjct: 2824 EKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLET 2883
Query: 397 NVSRDPSRLYKPTKGWEERTKKIGPTGSGP 426
V+ S + +K + +GP GP
Sbjct: 2884 QVAHLCS---QQSKQDSRGSPLLGPVVPGP 2910
Score = 49.3 bits (116), Expect = 7e-06
Identities = 91/412 (22%), Positives = 179/412 (43%), Gaps = 76/412 (18%)
Query: 71 KLREMMEEIENAINTFKEEQRLIYE---ELIKEEKTTN---NELSAISRKIDTWALGNSE 124
+L+ +E++ +N F+E Q + + ELI++EK N +EL + + D + +
Sbjct: 300 RLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTA 359
Query: 125 TEKAFRAISSKVPVDKVTPST----LPEEVLDFEK-FLQQTGGRQGAWDDYDH------- 172
E+ + ++ + + + L +++ + EK F ++ +Q ++ D
Sbjct: 360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKA 419
Query: 173 ---QNFVKVRNKHK------GKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFL-------- 215
Q + +N H K T +++ LE+ + + ++ + E+ +Q
Sbjct: 420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRR 479
Query: 216 ALEERKKESIQIWKTKKQQKREEIFKLKE-------------------KADNTP---VLF 253
++EE KKE+ + K+ +QK E+ L+ KA NT +L
Sbjct: 480 SMEEMKKEN-NLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLR 538
Query: 254 HNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQL--KEEEEKEKKHQKERQRQ 311
+++ NQ++ +K KLAV +KQ+ C+ L K E E+ + K + +
Sbjct: 539 DLQEKINQQENSLTLEKLKLAVADLEKQRD------CSQDLLKKREHHIEQLNDKLSKTE 592
Query: 312 FKLKLLLESYTQQKKEQEEFLRLEKEIRE--KAEKAEKRKNAADEISRFQERDLHKLELK 369
+ K LL + +KKE EE L+ EK + K+E + E Q + ++ LE
Sbjct: 593 KESKALLSALELKKKEYEE-LKEEKTLFSCWKSENEKLLTQMESEKENLQSK-INHLETC 650
Query: 370 ILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYK--PTKGWEERTKKI 419
+ +Q K E +++ R L E N+S + L+ +K E T+K+
Sbjct: 651 LKTQQIKSHEYNERVRTL----EMDRENLSVEIRNLHNVLDSKSVEVETQKL 698
Score = 42.7 bits (99), Expect = 7e-04
Identities = 73/421 (17%), Positives = 170/421 (40%), Gaps = 49/421 (11%)
Query: 11 NQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVE 70
N K++ + +EE+ L K + ++ N K++Q + + +
Sbjct: 2179 NSKAEVETLKTQIEEMARSL----KVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLS 2234
Query: 71 KLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAI----------SRKIDTWAL 120
+ ++EE E A KEE + E L + K N ++A+ + +D
Sbjct: 2235 SFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIE 2294
Query: 121 GNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQ-NFVKVR 179
+ + + +++ D+ + +++ + E GR ++ + + +
Sbjct: 2295 EEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRV---ENLERELEIARTN 2351
Query: 180 NKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEI 239
+H E+ G+ + + E Q LE + +++K+ E+
Sbjct: 2352 QEHAALEA------ENSKGEVETLKAKIEGMTQSLRGLE----LDVVTIRSEKENLTNEL 2401
Query: 240 FKLKEKADNTPVL---FHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKE 296
K +E+ ++ F N ++ +++K + ++K A+E + Q E++ + A+ +
Sbjct: 2402 QKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLK-ELNERVAALHND 2460
Query: 297 EEEKEKKHQKERQRQFKLKL----LLESYTQQKKE----QEEFLRLEKEIREKAEKAEKR 348
+E + K Q + L+L LL+ + K Q L +E+ + +K EK+
Sbjct: 2461 QEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKK 2520
Query: 349 KNAADEISRF------QERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDP 402
+EISR QE+ + KL + Q +++ + + +L++K++ S++
Sbjct: 2521 D---EEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNA 2577
Query: 403 S 403
S
Sbjct: 2578 S 2578
Score = 41.6 bits (96), Expect = 0.001
Identities = 78/404 (19%), Positives = 157/404 (38%), Gaps = 60/404 (14%)
Query: 41 IQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKE 100
++++L+ + + +L+ +L + +++L E M+E + + + E + E
Sbjct: 1949 LEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAE 2008
Query: 101 EKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEK----F 156
K L +S + + ++ +++ +T L ++ K
Sbjct: 2009 VKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELL 2068
Query: 157 LQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLP--GKTQDEVQQHEKWYQKF 214
++++ Q + D++ N K + E E TQ+EV Q + +K
Sbjct: 2069 VKESESLQARLSESDYEKL----NVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKL 2124
Query: 215 -LALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQE---------DNQKQK 264
+ +E +K+ + I + K+++RE LK+K +N +E +N K +
Sbjct: 2125 RVRIEADEKKQLHIAEKLKEREREND-SLKDKVENLERELQMSEENQELVILDAENSKAE 2183
Query: 265 EEQRK-----------------------KQKLAVEAWKKQKSIEMSMKCASQLK---EEE 298
E K K+ L + +KQ + K S K EE+
Sbjct: 2184 VETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEK 2243
Query: 299 EKEKKHQKERQR------QFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAA 352
E+ + KE + Q +LK L E+ +QE E+ + E+ + +N+
Sbjct: 2244 EQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSI 2303
Query: 353 DEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVEN 396
+++ E D K +L +L +Q KE E LK +VEN
Sbjct: 2304 EKLRARLEAD-EKKQLCVL-QQLKESE-----HHADLLKGRVEN 2340
Score = 41.2 bits (95), Expect = 0.002
Identities = 86/479 (17%), Positives = 191/479 (39%), Gaps = 104/479 (21%)
Query: 1 MEKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAK-IQQQLAKIHNNVKKLQHQL 59
ME + + F +QK IE+ L+ S+ T + + ++ +L + N +
Sbjct: 701 MELQQKAEFSDQKHQKEIENMCLKT-------SQLTGQVEDLEHKLQLLSNEIMDKDRCY 753
Query: 60 KDVKPTPDFVEKLREMMEEIENAINTFKEEQRLI------------YEELIKEEKTTNNE 107
+D+ E LR++++ + ++ T ++ QR + + +I E+ + +E
Sbjct: 754 QDLHAE---YESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSE 810
Query: 108 LSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAW 167
S + D ++ + ++ + K S L ++ E+ +Q G +
Sbjct: 811 RSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQC---EELVQIKGEIE--- 864
Query: 168 DDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQI 227
+N +K H+ +F+ E + + K Q++ H+ + L+ E K++ +Q+
Sbjct: 865 -----ENLMKAEQMHQ---SFVAETSQRI-SKLQEDTSAHQNVVAETLSALENKEKELQL 915
Query: 228 WKTKKQQKREEIFKLK----------------------EKADNTPVLFHNKQEDNQKQKE 265
K + ++ EI +LK EK + + ++ NK+E + +E
Sbjct: 916 LNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQE 975
Query: 266 -----------------------------EQRKKQKLAVEAWKKQKSIEMSMKCASQLKE 296
++R+K + KQ+ + + +C
Sbjct: 976 NGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNA 1035
Query: 297 EEEKEKKHQKERQRQFKLKLLLESYT----QQKKE----QEEFLRLEKEIREKAEKAEKR 348
E+ +K++ +++ KL+ LL T +K E +E F + +E K AE+R
Sbjct: 1036 YEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEER 1095
Query: 349 -KNAADEISRFQERDLHKLELKILDRQ-AKEDEKSQKQRRLAKLKEKVENNVSRDPSRL 405
+N E+ Q+ L ++ D Q + E ++ + LKE+ +N + ++ + L
Sbjct: 1096 NQNLMLELETVQQ----ALRSEMTDNQNNSKSEAGGLKQEIMTLKEE-QNKMQKEVNDL 1149
Score = 39.7 bits (91), Expect = 0.006
Identities = 61/355 (17%), Positives = 149/355 (41%), Gaps = 48/355 (13%)
Query: 12 QKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEK 71
+K +F + S +E ++L R I++ +I + KK H + +K +
Sbjct: 2099 EKGEFALRLSSTQEEVHQL-------RRGIEKLRVRIEADEKKQLHIAEKLKERERENDS 2151
Query: 72 LREMMEEIENAINTFKEEQRLIY---EELIKEEKTTNNELSAISRKIDTWALGNSETEKA 128
L++ +E +E + +E Q L+ E E +T ++ ++R + + L
Sbjct: 2152 LKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSE 2211
Query: 129 FRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTF 188
++ ++ + S L + + F+ L++ Q ++++ + K
Sbjct: 2212 KENLTKQIQEKQGQLSELDKLLSSFKSLLEEK-----------EQAEIQIKEESKTAVEM 2260
Query: 189 MEEVLEHLPGKT------QDEVQQHEKWYQKFLALEERKKESIQIWKTK---KQQKREEI 239
++ L+ L Q+ ++ E+ + E + + SI+ + + ++K+ +
Sbjct: 2261 LQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCV 2320
Query: 240 FKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQK-LAVEAWKKQKSIE------------- 285
+ +++++ L + E+ +++ E R Q+ A+EA + +E
Sbjct: 2321 LQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSL 2380
Query: 286 --MSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQ--QKKEQEEFLRLEK 336
+ + + E+E + QKE++R +L+++ S+ Q+KEQE+ EK
Sbjct: 2381 RGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEK 2435
Score = 36.2 bits (82), Expect = 0.062
Identities = 31/127 (24%), Positives = 66/127 (51%), Gaps = 16/127 (12%)
Query: 274 AVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQ-RQFKLKLLLESYTQQKK----EQ 328
A+E WK+ + + +++E E + K +KE+Q RQF+L L + +QK+ E+
Sbjct: 4 ALEEWKEG----LPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEK 59
Query: 329 EEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLA 388
E L++E + E E + +IS H+L++K +E + + ++++
Sbjct: 60 TEGTNLKRENQRLMEICESLEKTKQKIS-------HELQVKESQVNFQEGQLNSGKKQIE 112
Query: 389 KLKEKVE 395
KL+++++
Sbjct: 113 KLEQELK 119
Score = 32.7 bits (73), Expect = 0.68
Identities = 65/318 (20%), Positives = 130/318 (40%), Gaps = 36/318 (11%)
Query: 102 KTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTG 161
K T+NE + I+ + + SK+ + +V T E ++ EK + +
Sbjct: 1777 KETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELK 1836
Query: 162 GRQGAWDDY------DHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEV-----QQHEKW 210
+ DHQ ++ +G + +E H +++++ + ++ W
Sbjct: 1837 KENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEM---HADKSSREDIGDNVAKVNDSW 1893
Query: 211 YQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKK 270
++FL +E E +I K + E ++ +AD V Q + +++ K
Sbjct: 1894 KERFLDVEN---ELSRIRSEKASIEHEALYL---EADLEVV-----QTEKLCLEKDNENK 1942
Query: 271 QKLAVEAWKKQKSIEMSMKCASQLKEE-EEKEKKHQKERQRQFKLKLLLESYTQQKKEQE 329
QK+ V +++ S+ S + +QL+ E + KK Q K+K E + + Q
Sbjct: 1943 QKVIV-CLEEELSVVTSER--NQLRGELDTMSKKTTALDQLSEKMK---EKTQELESHQS 1996
Query: 330 EFLRL----EKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQR 385
E L E E++EK E + + E+ + + KL+ D QA K + +
Sbjct: 1997 ECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELEN 2056
Query: 386 RLAKLKEKVENNVSRDPS 403
++A+L ++ E V S
Sbjct: 2057 QIAQLNKEKELLVKESES 2074
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 69.3 bits (168), Expect = 7e-12
Identities = 45/196 (22%), Positives = 108/196 (55%), Gaps = 20/196 (10%)
Query: 197 PGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNK 256
PG +++QQ EK L E R+ E + ++++++EE+ + +E+ + +
Sbjct: 713 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEE------ILRRQ 766
Query: 257 QEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKL 316
QE+ +K++EE+ ++ EA ++Q+ E++++ ++ EE+E++ Q+E R+ +
Sbjct: 767 QEEERKRREEEELARRKQEEALRRQREQEIALR-----RQREEEERQQQEEALRRLE--- 818
Query: 317 LLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAK 376
++++E+EE + E+ +R++ E+A K +E R E + ++E + + +
Sbjct: 819 ------ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
Query: 377 EDEKSQKQRRLAKLKE 392
E+E+ +K+ + + KE
Sbjct: 873 EEERKRKELEVQRQKE 888
Score = 50.1 bits (118), Expect = 4e-06
Identities = 32/110 (29%), Positives = 63/110 (57%), Gaps = 5/110 (4%)
Query: 289 KCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEI-REKAEKAEK 347
K + +E E + K+ ++ER+RQ +L+ E ++++E+E R E+E+ R K E+A +
Sbjct: 730 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 789
Query: 348 RKNAADEISRFQ----ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEK 393
R+ + R Q ER + L+ L+ + +E+E+ +KQ L + +E+
Sbjct: 790 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 839
Score = 43.1 bits (100), Expect = 5e-04
Identities = 25/104 (24%), Positives = 63/104 (60%), Gaps = 5/104 (4%)
Query: 293 QLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAA 352
QL++ E+ + ++ +R+ +++ E +++K QEE R ++EI + ++ E+++
Sbjct: 719 QLQQLEKAKAAKLEQERREAEMRAKREE--EERKRQEELRRQQEEILRRQQEEERKRREE 776
Query: 353 DEISRFQERDL--HKLELKILDRQAKEDEKSQKQRR-LAKLKEK 393
+E++R ++ + + E +I R+ +E+E+ Q+Q L +L+E+
Sbjct: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER 820
Score = 41.6 bits (96), Expect = 0.001
Identities = 76/416 (18%), Positives = 168/416 (40%), Gaps = 81/416 (19%)
Query: 35 KTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIY 94
K + AK++Q+ + K+ + + K E+LR EEI + +EE+R
Sbjct: 725 KAKAAKLEQERREAEMRAKREEEERKRQ-------EELRRQQEEI---LRRQQEEERKRR 774
Query: 95 EELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFE 154
EE EE + A+ R+ E E A R + EE E
Sbjct: 775 EE---EELARRKQEEALRRQ--------REQEIALRRQREE------------EERQQQE 811
Query: 155 KFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKF 214
+ L++ R+ ++ Q + +R + + + E E ++ ++ E+ +
Sbjct: 812 EALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR 870
Query: 215 LALEERKKESIQIWKTK-----KQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRK 269
EERK++ +++ + K +QQ++E + +L+ Q+Q+++Q
Sbjct: 871 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQ-----------------QQQQQQQLA 913
Query: 270 KQKL-AVEAWKKQKSIE-------MSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESY 321
+ KL + W +Q + +S+ +L+EE E++ + ++ RQ++ +K L +
Sbjct: 914 QMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQ 973
Query: 322 TQQKKE-------------QEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLEL 368
QQ+++ + L +++E + +K ++++ + +R + L
Sbjct: 974 QQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHT 1033
Query: 369 KILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIGPTGS 424
I + + + L + +N S + W++ K++GP S
Sbjct: 1034 SIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNM----GFWDDAVKEVGPRNS 1085
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 69.3 bits (168), Expect = 7e-12
Identities = 45/196 (22%), Positives = 108/196 (55%), Gaps = 20/196 (10%)
Query: 197 PGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNK 256
PG +++QQ EK L E R+ E + ++++++EE+ + +E+ + +
Sbjct: 740 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEE------ILRRQ 793
Query: 257 QEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKL 316
QE+ +K++EE+ ++ EA ++Q+ E++++ ++ EE+E++ Q+E R+ +
Sbjct: 794 QEEERKRREEEELARRKQEEALRRQREQEIALR-----RQREEEERQQQEEALRRLE--- 845
Query: 317 LLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAK 376
++++E+EE + E+ +R++ E+A K +E R E + ++E + + +
Sbjct: 846 ------ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
Query: 377 EDEKSQKQRRLAKLKE 392
E+E+ +K+ + + KE
Sbjct: 900 EEERKRKELEVQRQKE 915
Score = 50.1 bits (118), Expect = 4e-06
Identities = 32/110 (29%), Positives = 63/110 (57%), Gaps = 5/110 (4%)
Query: 289 KCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEI-REKAEKAEK 347
K + +E E + K+ ++ER+RQ +L+ E ++++E+E R E+E+ R K E+A +
Sbjct: 757 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 816
Query: 348 RKNAADEISRFQ----ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEK 393
R+ + R Q ER + L+ L+ + +E+E+ +KQ L + +E+
Sbjct: 817 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 866
Score = 43.1 bits (100), Expect = 5e-04
Identities = 25/104 (24%), Positives = 63/104 (60%), Gaps = 5/104 (4%)
Query: 293 QLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAA 352
QL++ E+ + ++ +R+ +++ E +++K QEE R ++EI + ++ E+++
Sbjct: 746 QLQQLEKAKAAKLEQERREAEMRAKREE--EERKRQEELRRQQEEILRRQQEEERKRREE 803
Query: 353 DEISRFQERDL--HKLELKILDRQAKEDEKSQKQRR-LAKLKEK 393
+E++R ++ + + E +I R+ +E+E+ Q+Q L +L+E+
Sbjct: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER 847
Score = 41.6 bits (96), Expect = 0.001
Identities = 76/416 (18%), Positives = 168/416 (40%), Gaps = 81/416 (19%)
Query: 35 KTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIY 94
K + AK++Q+ + K+ + + K E+LR EEI + +EE+R
Sbjct: 752 KAKAAKLEQERREAEMRAKREEEERKRQ-------EELRRQQEEI---LRRQQEEERKRR 801
Query: 95 EELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFE 154
EE EE + A+ R+ E E A R + EE E
Sbjct: 802 EE---EELARRKQEEALRRQ--------REQEIALRRQREE------------EERQQQE 838
Query: 155 KFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKF 214
+ L++ R+ ++ Q + +R + + + E E ++ ++ E+ +
Sbjct: 839 EALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR 897
Query: 215 LALEERKKESIQIWKTK-----KQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRK 269
EERK++ +++ + K +QQ++E + +L+ Q+Q+++Q
Sbjct: 898 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQ-----------------QQQQQQQLA 940
Query: 270 KQKL-AVEAWKKQKSIE-------MSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESY 321
+ KL + W +Q + +S+ +L+EE E++ + ++ RQ++ +K L +
Sbjct: 941 QMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQ 1000
Query: 322 TQQKKE-------------QEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLEL 368
QQ+++ + L +++E + +K ++++ + +R + L
Sbjct: 1001 QQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHT 1060
Query: 369 KILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIGPTGS 424
I + + + L + +N S + W++ K++GP S
Sbjct: 1061 SIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNM----GFWDDAVKEVGPRNS 1112
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 69.3 bits (168), Expect = 7e-12
Identities = 45/196 (22%), Positives = 108/196 (55%), Gaps = 20/196 (10%)
Query: 197 PGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNK 256
PG +++QQ EK L E R+ E + ++++++EE+ + +E+ + +
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEE------ILRRQ 772
Query: 257 QEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKL 316
QE+ +K++EE+ ++ EA ++Q+ E++++ ++ EE+E++ Q+E R+ +
Sbjct: 773 QEEERKRREEEELARRKQEEALRRQREQEIALR-----RQREEEERQQQEEALRRLE--- 824
Query: 317 LLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAK 376
++++E+EE + E+ +R++ E+A K +E R E + ++E + + +
Sbjct: 825 ------ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
Query: 377 EDEKSQKQRRLAKLKE 392
E+E+ +K+ + + KE
Sbjct: 879 EEERKRKELEVQRQKE 894
Score = 50.1 bits (118), Expect = 4e-06
Identities = 32/110 (29%), Positives = 63/110 (57%), Gaps = 5/110 (4%)
Query: 289 KCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEI-REKAEKAEK 347
K + +E E + K+ ++ER+RQ +L+ E ++++E+E R E+E+ R K E+A +
Sbjct: 736 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 795
Query: 348 RKNAADEISRFQ----ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEK 393
R+ + R Q ER + L+ L+ + +E+E+ +KQ L + +E+
Sbjct: 796 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845
Score = 43.1 bits (100), Expect = 5e-04
Identities = 25/104 (24%), Positives = 63/104 (60%), Gaps = 5/104 (4%)
Query: 293 QLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAA 352
QL++ E+ + ++ +R+ +++ E +++K QEE R ++EI + ++ E+++
Sbjct: 725 QLQQLEKAKAAKLEQERREAEMRAKREE--EERKRQEELRRQQEEILRRQQEEERKRREE 782
Query: 353 DEISRFQERDL--HKLELKILDRQAKEDEKSQKQRR-LAKLKEK 393
+E++R ++ + + E +I R+ +E+E+ Q+Q L +L+E+
Sbjct: 783 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER 826
Score = 41.6 bits (96), Expect = 0.001
Identities = 76/416 (18%), Positives = 168/416 (40%), Gaps = 81/416 (19%)
Query: 35 KTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIY 94
K + AK++Q+ + K+ + + K E+LR EEI + +EE+R
Sbjct: 731 KAKAAKLEQERREAEMRAKREEEERKRQ-------EELRRQQEEI---LRRQQEEERKRR 780
Query: 95 EELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFE 154
EE EE + A+ R+ E E A R + EE E
Sbjct: 781 EE---EELARRKQEEALRRQ--------REQEIALRRQREE------------EERQQQE 817
Query: 155 KFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKF 214
+ L++ R+ ++ Q + +R + + + E E ++ ++ E+ +
Sbjct: 818 EALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR 876
Query: 215 LALEERKKESIQIWKTK-----KQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRK 269
EERK++ +++ + K +QQ++E + +L+ Q+Q+++Q
Sbjct: 877 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQ-----------------QQQQQQQLA 919
Query: 270 KQKL-AVEAWKKQKSIE-------MSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESY 321
+ KL + W +Q + +S+ +L+EE E++ + ++ RQ++ +K L +
Sbjct: 920 QMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQ 979
Query: 322 TQQKKE-------------QEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLEL 368
QQ+++ + L +++E + +K ++++ + +R + L
Sbjct: 980 QQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHT 1039
Query: 369 KILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIGPTGS 424
I + + + L + +N S + W++ K++GP S
Sbjct: 1040 SIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNM----GFWDDAVKEVGPRNS 1091
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 69.3 bits (168), Expect = 7e-12
Identities = 45/196 (22%), Positives = 108/196 (55%), Gaps = 20/196 (10%)
Query: 197 PGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNK 256
PG +++QQ EK L E R+ E + ++++++EE+ + +E+ + +
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEE------ILRRQ 772
Query: 257 QEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKL 316
QE+ +K++EE+ ++ EA ++Q+ E++++ ++ EE+E++ Q+E R+ +
Sbjct: 773 QEEERKRREEEELARRKQEEALRRQREQEIALR-----RQREEEERQQQEEALRRLE--- 824
Query: 317 LLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAK 376
++++E+EE + E+ +R++ E+A K +E R E + ++E + + +
Sbjct: 825 ------ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
Query: 377 EDEKSQKQRRLAKLKE 392
E+E+ +K+ + + KE
Sbjct: 879 EEERKRKELEVQRQKE 894
Score = 50.1 bits (118), Expect = 4e-06
Identities = 32/110 (29%), Positives = 63/110 (57%), Gaps = 5/110 (4%)
Query: 289 KCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEI-REKAEKAEK 347
K + +E E + K+ ++ER+RQ +L+ E ++++E+E R E+E+ R K E+A +
Sbjct: 736 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 795
Query: 348 RKNAADEISRFQ----ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEK 393
R+ + R Q ER + L+ L+ + +E+E+ +KQ L + +E+
Sbjct: 796 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845
Score = 43.1 bits (100), Expect = 5e-04
Identities = 25/104 (24%), Positives = 63/104 (60%), Gaps = 5/104 (4%)
Query: 293 QLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAA 352
QL++ E+ + ++ +R+ +++ E +++K QEE R ++EI + ++ E+++
Sbjct: 725 QLQQLEKAKAAKLEQERREAEMRAKREE--EERKRQEELRRQQEEILRRQQEEERKRREE 782
Query: 353 DEISRFQERDL--HKLELKILDRQAKEDEKSQKQRR-LAKLKEK 393
+E++R ++ + + E +I R+ +E+E+ Q+Q L +L+E+
Sbjct: 783 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER 826
Score = 41.6 bits (96), Expect = 0.001
Identities = 76/416 (18%), Positives = 168/416 (40%), Gaps = 81/416 (19%)
Query: 35 KTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIY 94
K + AK++Q+ + K+ + + K E+LR EEI + +EE+R
Sbjct: 731 KAKAAKLEQERREAEMRAKREEEERKRQ-------EELRRQQEEI---LRRQQEEERKRR 780
Query: 95 EELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFE 154
EE EE + A+ R+ E E A R + EE E
Sbjct: 781 EE---EELARRKQEEALRRQ--------REQEIALRRQREE------------EERQQQE 817
Query: 155 KFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKF 214
+ L++ R+ ++ Q + +R + + + E E ++ ++ E+ +
Sbjct: 818 EALRRLEERRREEEERRKQEEL-LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLR 876
Query: 215 LALEERKKESIQIWKTK-----KQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRK 269
EERK++ +++ + K +QQ++E + +L+ Q+Q+++Q
Sbjct: 877 HEEEERKRKELEVQRQKELMRQRQQQQEALRRLQ-----------------QQQQQQQLA 919
Query: 270 KQKL-AVEAWKKQKSIE-------MSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESY 321
+ KL + W +Q + +S+ +L+EE E++ + ++ RQ++ +K L +
Sbjct: 920 QMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQ 979
Query: 322 TQQKKE-------------QEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLEL 368
QQ+++ + L +++E + +K ++++ + +R + L
Sbjct: 980 QQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHT 1039
Query: 369 KILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKIGPTGS 424
I + + + L + +N S + W++ K++GP S
Sbjct: 1040 SIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNM----GFWDDAVKEVGPRNS 1091
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 68.6 bits (166), Expect = 1e-11
Identities = 103/442 (23%), Positives = 196/442 (44%), Gaps = 70/442 (15%)
Query: 13 KSDFRIEHSMLEELENKLIHSRKTERAKIQQQ--LAKIHNNVKKLQHQLKD-VKPTPDFV 69
K+ + ++LE + + HS K E+ ++++ + K+ N+K+ Q L+D VK T D
Sbjct: 1120 KAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLN 1179
Query: 70 EKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAF 129
K ++ EEI N ++ + L+ +L +EE+ TN + +T L + +
Sbjct: 1180 VKELKLKEEITQLTNNLQDMKHLL--QLKEEEEETNRQ--------ETEKLKEELSASSA 1229
Query: 130 RAISSKVPVDKVTP--STLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPT 187
R + K + + + L E++ D +K ++Q D D +K+ K K
Sbjct: 1230 RTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQ 1289
Query: 188 FMEEV----------LEHLPG-KTQDEVQQHEKWYQKF-----------LALEERKKESI 225
+E+ E L K ++ +QQ+E+ + + LEE+++ +
Sbjct: 1290 CSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQV 1349
Query: 226 ---QIWKTKKQQKRE---EIFKLKEKADNTPVLFH---NKQEDNQK---------QKEEQ 267
Q+ + K ++ E+ K KEK ++ + NK+ +N Q E Q
Sbjct: 1350 EQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQ 1409
Query: 268 RKKQKLAVEAWKKQKSIEMSMKCASQLKEEE----EKEKKHQKERQRQFKLKLLLESYTQ 323
+QK + ++K +E M +Q KE E ++ KK+ ++R+R FK + +E T
Sbjct: 1410 ESEQKYNAD---RKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTA 1466
Query: 324 QKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQK 383
Q E++ L+ +E R++ A + + A S Q+ + E++ L R E K +
Sbjct: 1467 QLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDN----EIEQLKRIISETSKIET 1522
Query: 384 QRRLAKLKEKVENNVSRDPSRL 405
Q + +K K S DP +L
Sbjct: 1523 Q--IMDIKPK--RISSADPDKL 1540
Score = 65.1 bits (157), Expect = 1e-10
Identities = 87/434 (20%), Positives = 195/434 (44%), Gaps = 55/434 (12%)
Query: 11 NQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAK--IHNNVKKLQHQLKDVKPTPDF 68
N + + ++ L+ L N + S++ + +IQ+ + H++++ + + K++
Sbjct: 974 NGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIVKASSK 1033
Query: 69 ----VEKLREMMEEIENAINTFKEEQRLIYE-------ELIKEEKTT----NNELSAISR 113
+E+L + +E+++ + +K+E + E +L+KE++T EL +
Sbjct: 1034 KSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNV 1093
Query: 114 KIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQ 173
+D E ++A ++ V K L E +L+ +K ++ + + D + +
Sbjct: 1094 TLDVQIQHVVEGKRALSELTQGVTCYKAKIKEL-ETILETQK-VECSHSAKLEQDILEKE 1151
Query: 174 NFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEER----------KKE 223
+ + ++ ++E EHL QD V+ + K L L+E K
Sbjct: 1152 SIILKLERN------LKEFQEHL----QDSVKNTKDLNVKELKLKEEITQLTNNLQDMKH 1201
Query: 224 SIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKS 283
+Q+ + +++ R+E KLKE+ + N + D Q+++E+ ++ +A K+ K
Sbjct: 1202 LLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQ 1261
Query: 284 IEMSMKCAS------QLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKE 337
++ + ++K E ++KK+Q ++ K + + QQ KEQ ++E+
Sbjct: 1262 VQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTI-----QQLKEQLNNQKVEEA 1316
Query: 338 IREKAEKAEKRKNAADEISRFQERDLHKLELKILDR----QAKEDEKSQKQRRLAKLKEK 393
I ++ E+A K N ++I L + E +++ +AK +E + L K KEK
Sbjct: 1317 I-QQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEK 1375
Query: 394 VENNVSRDPSRLYK 407
+ +++ R K
Sbjct: 1376 CNDLETKNNQRSNK 1389
Score = 54.7 bits (130), Expect = 2e-07
Identities = 82/437 (18%), Positives = 177/437 (40%), Gaps = 66/437 (15%)
Query: 11 NQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKI---------HNNVKKLQHQLKD 61
N D + ++EELEN ++ E + + L K H +KL ++D
Sbjct: 524 NSLEDLMEDEDLVEELENAE-ETQNVETKLLDEDLDKTLEENKAFISHEEKRKLLDLIED 582
Query: 62 VKPT--PDFVEKLR---EMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKID 116
+K + EKL ++ EE+ + ++ ++E + +E+ E + I
Sbjct: 583 LKKKLINEKKEKLTLEFKIREEVTQEFTQYWAQREADFKETLLQEREILEENAERRLAIF 642
Query: 117 TWALGNSET--EKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQN 174
+G +T E A ++KV ++ T L F + + +G
Sbjct: 643 KDLVGKCDTREEAAKDICATKVETEEATACL----ELKFNQIKAELAKTKG--------E 690
Query: 175 FVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQ 234
+K + + K + + +++ L + + Q+++ ++ + + ++K+++I ++ K
Sbjct: 691 LIKTKEELKKRENESDSLIQELETSNKKIITQNQR-IKELINIIDQKEDTINEFQNLKSH 749
Query: 235 KREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWK-------------KQ 281
E FK +KAD + ++ +NK N+ + + K K+ E + K+
Sbjct: 750 M-ENTFKCNDKADTSSLIINNKLICNETVEVPKDSKSKICSERKRVNENELQQDEPPAKK 808
Query: 282 KSIEMSMKCASQLKEEEEK-------EKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRL 334
SI +S K+ EE E + + LL + K E+EE L
Sbjct: 809 GSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLTIENELKNEKEEKAEL 868
Query: 335 EKEI----REKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKL 390
K+I +E + +K + E+ + Q ++ I + ++ + +++ ++ KL
Sbjct: 869 NKQIVHFQQELSLSEKKNLTLSKEVQQIQS----NYDIAIAELHVQKSKNQEQEEKIMKL 924
Query: 391 KEKVE-------NNVSR 400
++E NNVS+
Sbjct: 925 SNEIETATRSITNNVSQ 941
Score = 43.1 bits (100), Expect = 5e-04
Identities = 79/411 (19%), Positives = 162/411 (39%), Gaps = 58/411 (14%)
Query: 58 QLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELI----------KEEKTTNNE 107
+++D++ + E LR + IEN + KEE+ + ++++ K+ T + E
Sbjct: 833 EIEDIRVLQENNEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKE 892
Query: 108 LSAISRKID-------TWALGNSETEKAFRAISSKVPVD--KVTPSTLPEEVLDFEKFLQ 158
+ I D N E E+ +S+++ +T + +++ +
Sbjct: 893 VQQIQSNYDIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDEL 952
Query: 159 QTGGRQGAWDDYDHQNFVKVRN--KHKGKPTFMEEVL--EHLPGKTQDEVQQHE-----K 209
+T + D N + N + P ++L ++L K E + E
Sbjct: 953 RTLDSVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENS 1012
Query: 210 WYQKFLALEERKKESIQIWKTKKQQKRE----------EIFKLKEKADNTPVLFHNKQED 259
++ A+ E KE ++ K Q E E+ K++ + H Q+D
Sbjct: 1013 FHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDD 1072
Query: 260 NQKQKEE--QRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLL 317
K+KE Q+ K++L ++K++ + ++ ++ + + Q + K+K L
Sbjct: 1073 LLKEKETLIQQLKEEL------QEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKEL 1126
Query: 318 LESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQE---------RDLHKLEL 368
QK E +LE++I EK K + + FQE +DL+ EL
Sbjct: 1127 ETILETQKVECSHSAKLEQDILEKESIILKLER---NLKEFQEHLQDSVKNTKDLNVKEL 1183
Query: 369 KILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKKI 419
K+ + + Q + L +LKE+ E ++ +L + RT+ +
Sbjct: 1184 KLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNL 1234
>gi|31377611 coiled-coil domain containing 148 [Homo sapiens]
Length = 591
Score = 68.2 bits (165), Expect = 1e-11
Identities = 92/426 (21%), Positives = 189/426 (44%), Gaps = 48/426 (11%)
Query: 23 LEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQ-LKDVKPTPDFVEKLREMMEEIEN 81
L E +L + T + + ++ ++K QH L+ P +F +++EE++
Sbjct: 108 LTNFEQELSEQQCTYLKNVINPIQQLRADLKYRQHHTLQHSHPHIEF--NSMKVLEEVDF 165
Query: 82 AINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALG---NSETEKAFRAISSKVPV 138
K++ + ++E L E++ N+LS S KI +L N +E S + P
Sbjct: 166 V----KKQLKTVFERLRLEQQRIENDLSDWSIKILDHSLEEKTNPLSELPIELESLECPY 221
Query: 139 DKVTPSTLPE----------EVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKG---- 184
+ S L E ++ DF L+ R + DH + + +++ G
Sbjct: 222 PDLKSSILSEFYKFTQKYQKKLQDFNLQLEDIY-RNCQLSEEDHWIYQAILDQYPGDLFG 280
Query: 185 -KPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIW-KTKKQQKREEIFKL 242
+ +++ + + P K++ ++ +HEK+ ++ E++ I W K +K ++ + L
Sbjct: 281 RRTLYLDMLQRYFPHKSRHDLVEHEKYCDQYRFAIEQQNILISNWNKNRKDFIQKAVLTL 340
Query: 243 KEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKS----IEMSMKCASQLKEEE 298
E + + ++K+++E K V W+ + +EM + + KEEE
Sbjct: 341 TEACATHEM--ESMLAKDKKKQQELCADLKAKVRQWRAHQEEVARLEMEISARRREKEEE 398
Query: 299 EKEKKHQKERQRQFKLKLLLESYTQQKK------EQEEFLRLE---KEIREKAEKAEKRK 349
+++ +KE ++ + K ++ Y +KK E + RLE K I E++ K +R
Sbjct: 399 KEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQSLKDRERV 458
Query: 350 NAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPT 409
E+ + R + K E+ + ++A ED+ ++ RRL L+++V DP R+ T
Sbjct: 459 KYRQEL--LERRLMEKKEVAL--QEAHEDK--ERARRLEALRKQVAVVAQFDPVRMMSDT 512
Query: 410 KGWEER 415
+ R
Sbjct: 513 MASKAR 518
Score = 32.7 bits (73), Expect = 0.68
Identities = 32/167 (19%), Positives = 70/167 (41%), Gaps = 25/167 (14%)
Query: 199 KTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEI------------------- 239
+ + E ++ + W +K L KK+ I+ + KK+QK +E+
Sbjct: 392 RREKEEEKEKLWKKKELLQRAEKKKKIKKYWAKKKQKWQEMEMRDLQRLEELKKLIAEQS 451
Query: 240 FKLKEKADNTPVLFHNKQEDNQK---QKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKE 296
K +E+ L + + ++ Q+ + K++ +EA +KQ ++ + +
Sbjct: 452 LKDRERVKYRQELLERRLMEKKEVALQEAHEDKERARRLEALRKQVAVVAQFDPVRMMSD 511
Query: 297 EEEKEKKHQKERQRQFKLK---LLLESYTQQKKEQEEFLRLEKEIRE 340
+ + E + +F L+ L +Y +Q+ + LR E +RE
Sbjct: 512 TMASKARMGIEIEEEFILQKPLFTLNTYNEQQIISDPRLRFELALRE 558
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 66.2 bits (160), Expect = 6e-11
Identities = 80/421 (19%), Positives = 177/421 (42%), Gaps = 33/421 (7%)
Query: 12 QKSDFRIEHSMLEELENKLIHSRKTE---RAKIQQQLAKIHNNVKKLQHQLKDVKPTPDF 68
QK + LEE +N L ++ E R +++Q+ + + + + ++ D T +
Sbjct: 1330 QKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIES 1389
Query: 69 VEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKA 128
+E+ ++ + + A++ EE+ L Y++L K + EL ++ +D S EK
Sbjct: 1390 LEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKK 1449
Query: 129 FRAISSKVPVDKVTPSTLPEE--------------VLDFEKFLQQTGGRQGAWDDYDHQN 174
+ + +K + EE L + L++ + ++ + Q
Sbjct: 1450 QKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQL 1509
Query: 175 FVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQ------QHEKWYQKFLALEERKKESIQIW 228
+ + K + V E K E Q Q E+ + A E+ K
Sbjct: 1510 RADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNM 1569
Query: 229 KTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQ----KSI 284
+ K Q ++ E+ + L + + + + E++RK++ LAV + KK K +
Sbjct: 1570 QAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDL 1629
Query: 285 EMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLL------ESYTQQKKEQEEFLRLEKEI 338
E ++ A++ ++E K+ + + + + ++ +L E + Q K+ +++ LE EI
Sbjct: 1630 EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEI 1689
Query: 339 REKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNV 398
+ E+ + A + ++ ++ + A DEK + + R+A+L+E++E
Sbjct: 1690 LQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQ 1749
Query: 399 S 399
S
Sbjct: 1750 S 1750
Score = 55.1 bits (131), Expect = 1e-07
Identities = 87/438 (19%), Positives = 187/438 (42%), Gaps = 73/438 (16%)
Query: 2 EKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQL-- 59
E++++ N+K + +++LE +L + R K+Q + +KK++ ++
Sbjct: 934 EEERNQILQNEKKKMQAH---IQDLEEQL-DEEEGARQKLQLEKVTAEAKIKKMEEEILL 989
Query: 60 ---------KDVKPTPDFV-EKLREMMEEIENAINTFK---EEQRLI--YEELIKEEKTT 104
K+ K D + E ++ EE E A N K +++ +I EE +K+E+ T
Sbjct: 990 LEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKT 1049
Query: 105 NNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQ 164
EL RK+D T+ + + +D++ L K ++ G
Sbjct: 1050 RQELEKAKRKLD-----GETTDLQDQIAELQAQIDELK--------LQLAKKEEELQGAL 1096
Query: 165 GAWDD--YDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKK 222
DD N +KV + + + ++E E +Q ++ AL+ +
Sbjct: 1097 ARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELE 1156
Query: 223 ESI------QIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVE 276
+++ Q +TK++Q+ E+ K E+ + ++++ Q ++ R++ A+E
Sbjct: 1157 DTLDTTAAQQELRTKREQEVAELKKALEE----------ETKNHEAQIQDMRQRHATALE 1206
Query: 277 AWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKL--KLLLESYTQQKKEQEEFLRL 334
+Q +E + + + L++ ++ + KE + K+ ++ ES ++KK + L
Sbjct: 1207 ELSEQ--LEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264
Query: 335 EKEIR-------EKAEKAEKRKNAADEISRFQE----------RDLHKLELKILDRQAKE 377
++ E AEKA K +N D +S E +D LE ++ D Q
Sbjct: 1265 HAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELL 1324
Query: 378 DEKSQKQRRLAKLKEKVE 395
E+++++ L+ ++E
Sbjct: 1325 QEETRQKLNLSSRIRQLE 1342
Score = 52.4 bits (124), Expect = 8e-07
Identities = 81/418 (19%), Positives = 177/418 (42%), Gaps = 40/418 (9%)
Query: 1 MEKDKHSHFYNQKSDFRIEHSM-LEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQL 59
+E++ +H Q D R H+ LEEL +L +++ +A +++ + + K+L ++
Sbjct: 1183 LEEETKNH-EAQIQDMRQRHATALEELSEQLEQAKRF-KANLEKNKQGLETDNKELACEV 1240
Query: 60 KDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWA 119
K ++ E R+ ++ ++ E + EL ++ NEL +S ++
Sbjct: 1241 KVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAE 1300
Query: 120 LGNSETEKAFRAISSKVPVDKVTPSTLPEEV---LDFEKFLQQTGGRQGAWDDYDHQNFV 176
+ K ++ S++ + T L EE L+ ++Q + + + +
Sbjct: 1301 KKGIKFAKDAASLESQL---QDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEE 1357
Query: 177 KVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKR 236
+N K + ++ L K D++ E +LEE KK+ ++ + Q+
Sbjct: 1358 ARKNLEK-QVLALQSQLADTKKKVDDDLGTIE-------SLEEAKKKLLKDAEALSQRLE 1409
Query: 237 EEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIE--MSMKCASQL 294
E+ +K + T + +D + QR+ +A KKQK + ++ + +
Sbjct: 1410 EKALAY-DKLEKTKNRLQQELDDLTVDLDHQRQ---VASNLEKKQKKFDQLLAEEKSISA 1465
Query: 295 KEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAE----------- 343
+ EE+++ + R+++ K L + + + +EEF R K++R E
Sbjct: 1466 RYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGK 1525
Query: 344 ---KAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNV 398
+ EK K A ++ L +LE ++ QA ED K + + + +K + E ++
Sbjct: 1526 NVHELEKSKRALEQQVEEMRTQLEELEDEL---QATEDAKLRLEVNMQAMKAQFERDL 1580
Score = 49.3 bits (116), Expect = 7e-06
Identities = 87/402 (21%), Positives = 167/402 (41%), Gaps = 78/402 (19%)
Query: 4 DKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVK 63
D+ H N R + + EL+ S K R K ++Q + ++ L+ +L+D
Sbjct: 1101 DETLHKNNALKVVRELQAQIAELQEDF-ESEKASRNKAEKQKRDLSEELEALKTELEDTL 1159
Query: 64 PTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTN-NELSAISRKIDTWALGN 122
T ++LR E+ + EE+ +E I++ + + L +S ++
Sbjct: 1160 DTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQL------- 1212
Query: 123 SETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKH 182
E K F+A K +K T +E+ K LQQ VK ++H
Sbjct: 1213 -EQAKRFKANLEK---NKQGLETDNKELACEVKVLQQ----------------VKAESEH 1252
Query: 183 KGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKL 242
K K K +VQ+ L + E ++ + + E+ KL
Sbjct: 1253 KRK-------------KLDAQVQE----------LHAKVSEGDRL----RVELAEKASKL 1285
Query: 243 KEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEK 302
+ + DN L +E ++K K A +A S+E ++ +L +EE ++K
Sbjct: 1286 QNELDNVSTLL----------EEAEKKGIKFAKDA----ASLESQLQDTQELLQEETRQK 1331
Query: 303 KHQKERQRQFKLKLLLESYTQQKKEQEEFLR--LEKEIRE-KAEKAEKRKNAADEISRFQ 359
+ R RQ + + ++ Q+++E+EE R LEK++ +++ A+ +K D++ +
Sbjct: 1332 LNLSSRIRQLEEE---KNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIE 1388
Query: 360 ERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRD 401
+ K +L + D +A +K KL EK +N + ++
Sbjct: 1389 SLEEAKKKL-LKDAEALSQRLEEKALAYDKL-EKTKNRLQQE 1428
Score = 48.9 bits (115), Expect = 9e-06
Identities = 61/248 (24%), Positives = 110/248 (44%), Gaps = 66/248 (26%)
Query: 206 QHEKWYQKFLALEERKKESIQIWKTKK--QQKREEIFKLKEKADNTPVLFHNKQEDNQKQ 263
+H +W++ F + K +Q+ + ++ Q K EE+ K+KEK + +Q+
Sbjct: 830 RHWQWWRVFTKV----KPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQL 885
Query: 264 KEEQR---------------KKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKER 308
EE+ ++ A A KKQ+ E+ S+++EEEE+ + Q E+
Sbjct: 886 LEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEK 945
Query: 309 QRQ----------------FKLKLLLESYTQQ---KKEQEEFLRLE----KEIREK---- 341
++ + KL LE T + KK +EE L LE K I+EK
Sbjct: 946 KKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME 1005
Query: 342 ----------AEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLK 391
AE+ EK KN A + R+ ++ + L+ + K++EK++++ L K K
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLA------KIRNKQEVMISDLEERLKKEEKTRQE--LEKAK 1057
Query: 392 EKVENNVS 399
K++ +
Sbjct: 1058 RKLDGETT 1065
Score = 47.4 bits (111), Expect = 3e-05
Identities = 88/429 (20%), Positives = 177/429 (41%), Gaps = 87/429 (20%)
Query: 24 EELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMME----EI 79
+ELE +++H ++ + +++ + N KK+Q ++D++ D E R+ ++
Sbjct: 918 QELE-EILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTA 976
Query: 80 ENAINTFKEEQRLIYEE---LIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKV 136
E I +EE L+ ++ IKE+K + ++ S ++ +E E+ + ++
Sbjct: 977 EAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQL-------AEEEEKAKNLAKIR 1029
Query: 137 PVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHL 196
+V S L E + EK Q K + K G+ T +++ + L
Sbjct: 1030 NKQEVMISDLEERLKKEEK---------------TRQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 197 PGKTQD---EVQQHEKWYQKFLAL--------------------------EERKKESIQI 227
+ + ++ + E+ Q LA E+ + E
Sbjct: 1075 QAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASR 1134
Query: 228 WKTKKQQK--REEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKS-- 283
K +KQ++ EE+ LK + ++T +QE K+++E + +K E K ++
Sbjct: 1135 NKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQI 1194
Query: 284 IEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIRE--K 341
+M + A+ L+E E Q E+ ++FK LE Q + + L E ++ + K
Sbjct: 1195 QDMRQRHATALEELSE-----QLEQAKRFKAN--LEKNKQGLETDNKELACEVKVLQQVK 1247
Query: 342 AEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRD 401
AE KRK KL+ ++ + AK E + + LA+ K++N +
Sbjct: 1248 AESEHKRK---------------KLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNV 1292
Query: 402 PSRLYKPTK 410
+ L + K
Sbjct: 1293 STLLEEAEK 1301
Score = 46.6 bits (109), Expect = 5e-05
Identities = 78/380 (20%), Positives = 170/380 (44%), Gaps = 48/380 (12%)
Query: 45 LAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTT 104
L ++ ++LQ + +++ + K+ +EE+E EE+ ++ E+L E
Sbjct: 844 LLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAE---- 899
Query: 105 NNELSAISRKIDT-WALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQ----Q 159
EL A + ++ A E E+ + S+V ++ L E + +Q Q
Sbjct: 900 -TELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQ 958
Query: 160 TGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEE 219
+GA Q + + K MEE + L Q+ K+ ++ +E+
Sbjct: 959 LDEEEGA-----RQKLQLEKVTAEAKIKKMEEEILLLE-------DQNSKFIKEKKLMED 1006
Query: 220 RKKE-SIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEE-QRKKQKLAVEA 277
R E S Q+ ++++K + + K++ K + + + +K ++E ++ K+KL E
Sbjct: 1007 RIAECSSQL--AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET 1064
Query: 278 WKKQKSI--------EMSMKCASQLKEEEEKE----KKHQKERQRQFKLKLLLESYTQQK 325
Q I E+ ++ A K+EEE + + + + LK++ E Q
Sbjct: 1065 TDLQDQIAELQAQIDELKLQLA---KKEEELQGALARGDDETLHKNNALKVVRELQAQIA 1121
Query: 326 KEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQR 385
+ QE+F EK R KAEK ++++ ++E+ + +LE + A+++ ++++++
Sbjct: 1122 ELQEDF-ESEKASRNKAEK--QKRDLSEELEALKT----ELEDTLDTTAAQQELRTKREQ 1174
Query: 386 RLAKLKEKVENNVSRDPSRL 405
+A+LK+ +E +++
Sbjct: 1175 EVAELKKALEEETKNHEAQI 1194
Score = 46.6 bits (109), Expect = 5e-05
Identities = 79/425 (18%), Positives = 178/425 (41%), Gaps = 73/425 (17%)
Query: 2 EKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKD 61
E+D + + R+ + ELE +L RK +RA K+ ++K L+ Q++
Sbjct: 1577 ERDLQTRDEQNEEKKRLLIKQVRELEAELEDERK-QRALAVASKKKMEIDLKDLEAQIEA 1635
Query: 62 V-KPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWAL 120
K + +++LR++ ++++ Y+ ++E + + +E+ A S+
Sbjct: 1636 ANKARDEVIKQLRKLQAQMKD------------YQRELEEARASRDEIFAQSK------- 1676
Query: 121 GNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRN 180
E+EK +++ +++ L EE+ E+ + + D ++ N
Sbjct: 1677 ---ESEKKLKSLEAEI-------LQLQEELASSERARRHAEQERDELAD-------EITN 1719
Query: 181 KHKGKPTFMEEV--LEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREE 238
GK ++E LE + ++E+++ + + L + +K ++Q+ + E
Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSNME--LLNDRFRKTTLQVDTLNAELAAER 1777
Query: 239 IFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCA-SQLKEE 297
+K+DN +Q+ ++ KE + K Q+L K K+ +++ QL+E+
Sbjct: 1778 --SAAQKSDNA------RQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQ 1829
Query: 298 EEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISR 357
E+E K + + + R EK+++E + E + AD+
Sbjct: 1830 LEQEAKERAAANKLVR-------------------RTEKKLKEIFMQVEDERRHADQYKE 1870
Query: 358 FQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVE-NNVSRDPSRLYKPTKGWEERT 416
E+ +K L RQ +E E+ + ++ K + E ++ + L + + R
Sbjct: 1871 QMEK--ANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRL 1928
Query: 417 KKIGP 421
++ GP
Sbjct: 1929 RRGGP 1933
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 64.7 bits (156), Expect = 2e-10
Identities = 52/217 (23%), Positives = 104/217 (47%), Gaps = 16/217 (7%)
Query: 201 QDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDN 260
Q E+++ E+ E +KE + +++++++R E K K + + K+E
Sbjct: 35 QSEIREREREI-------ETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKK 87
Query: 261 QKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLES 320
++K+E+R+++K E K+ K E K + K+E + K KER+R+ + K
Sbjct: 88 GERKKEERERKKRRRE--KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
Query: 321 YTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEK 380
++KKE+ E E+E +E+ ++ K+ +E + +ER K + + KE E+
Sbjct: 146 ERERKKEERE---KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERER 202
Query: 381 SQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTK 417
+++ R + K+K E R R W E+ +
Sbjct: 203 KERRERKKERKKKEERKKERQKDR----QTNWREKER 235
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/202 (26%), Positives = 103/202 (50%), Gaps = 25/202 (12%)
Query: 228 WKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMS 287
W+++ +++ EI KE K+E ++K+E+R+++K E K++K E
Sbjct: 34 WQSEIREREREIETRKE----------GKKERESERKKERREREKRKREREKERKR-ERG 82
Query: 288 MKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEK 347
K + K E +KE++ +K+R+R+ + K E ++KKE++E R KE +E+ K E+
Sbjct: 83 KK---EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEER 139
Query: 348 RKNAADEISRFQE--------RDLHKLELKIL---DRQAKEDEKSQKQRRLAKLKEKVEN 396
++ E R +E ++ K E K + + + KE E+ ++++R KE+ +
Sbjct: 140 KREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE 199
Query: 397 NVSRDPSRLYKPTKGWEERTKK 418
++ K K EER K+
Sbjct: 200 RERKERRERKKERKKKEERKKE 221
Score = 60.8 bits (146), Expect = 2e-09
Identities = 45/191 (23%), Positives = 93/191 (48%), Gaps = 18/191 (9%)
Query: 179 RNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREE 238
R + + K E + G+ + E ++ +K + E+ KE + K KK++K+E
Sbjct: 69 RKREREKERKRERGKKEKKGERKKEERERKKRRR-----EKENKEGEEKEKRKKKEKKER 123
Query: 239 IFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEE 298
KE + ++ +++KE +RKK++ E +K++ + + +E +
Sbjct: 124 GRTSKEGKERE----RKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERK 179
Query: 299 EKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRF 358
EKE+K +K+R+R K ++KKE+E R E++ K ++ K++ D + +
Sbjct: 180 EKERKERKKRERNRK---------ERKKERERKERRERKKERKKKEERKKERQKDRQTNW 230
Query: 359 QERDLHKLELK 369
+E++ K E K
Sbjct: 231 REKERGKRERK 241
Score = 59.7 bits (143), Expect = 5e-09
Identities = 45/204 (22%), Positives = 108/204 (52%), Gaps = 15/204 (7%)
Query: 191 EVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTP 250
E+ GK + E ++ ++ ++ ER+KE + + KK++K E + +E+
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRE-RGKKEKKGERKKEERERKKRRR 102
Query: 251 VLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQR 310
+ + E+ +K+K++++K++ + K+++ E + + KE E K+++ +KER+R
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR--EERKERERKKEEREKERER 160
Query: 311 QFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKI 370
+ ++KK + + + ++E R++ E+ E++K + R +ER+ + +
Sbjct: 161 K-----------ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209
Query: 371 LDRQAKEDEKSQKQR-RLAKLKEK 393
+R+ KE+ K ++Q+ R +EK
Sbjct: 210 KERKKKEERKKERQKDRQTNWREK 233
Score = 37.0 bits (84), Expect = 0.036
Identities = 32/134 (23%), Positives = 67/134 (50%), Gaps = 12/134 (8%)
Query: 286 MSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKA 345
+S C + E +E++ + E +++ K E +++KKE+ E + ++E REK K
Sbjct: 25 ISKPCTQPGWQSEIREREREIETRKEGK----KERESERKKERREREKRKRE-REKERKR 79
Query: 346 EKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRD-PSR 404
E+ K + +ER+ K R+ KE+++ +++ + K ++K S++ R
Sbjct: 80 ERGKKEKKGERKKEERERKK------RRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
Query: 405 LYKPTKGWEERTKK 418
K + EER ++
Sbjct: 134 ERKEERKREERKER 147
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 64.7 bits (156), Expect = 2e-10
Identities = 86/396 (21%), Positives = 183/396 (46%), Gaps = 55/396 (13%)
Query: 22 MLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIEN 81
M +ELE K+ + + ++ + + ++++ + LKD + +L +++E +
Sbjct: 717 MKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQ------INQLELLLKERDK 770
Query: 82 AINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKV 141
+ KE Q + E L + K + EL S K+D + S T + +A ++
Sbjct: 771 HL---KEHQAHV-ENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQL----- 821
Query: 142 TPSTLPEEVLDFE--KFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGK 199
+ L +++LD E + L +Q A + ++ + HK + + + LE +
Sbjct: 822 --AQLQQKLLDLETERILLT---KQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE 876
Query: 200 TQDEVQQHEKWYQKFLALEERKKESIQ-----------IWKTKKQQKRE-EIF--KLKEK 245
+ +V+ + Y+ LE+ KE Q I + ++ QK+E EI KL K
Sbjct: 877 MEQKVKSLTQVYES--KLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAK 934
Query: 246 ADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSM-KCASQLKEEEEKEKKH 304
D+ +L +E K K +++K +K+ +A + Q++++ + ++LK+E E
Sbjct: 935 EDSIHIL---NEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALE 991
Query: 305 QKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLH 364
++++QF K+L + + RLE +E+ E + E+ R + D+
Sbjct: 992 LSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIE-------SLTEVHRRELNDVI 1044
Query: 365 KLELKILDRQAKEDEK------SQKQRRLAKLKEKV 394
+ K L++QA+E ++ +K++ +A+LK+K+
Sbjct: 1045 SIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKI 1080
Score = 60.1 bits (144), Expect = 4e-09
Identities = 92/403 (22%), Positives = 165/403 (40%), Gaps = 53/403 (13%)
Query: 23 LEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENA 82
L+ELE K+ E+ K+ QL N +++L+ V E R+M E +E
Sbjct: 327 LQELE-KIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMV-----IAETKRQMHETLE-- 378
Query: 83 INTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSE--------TEKAFRAISS 134
KEE+ IK+ T EL K + A E TE+A R + +
Sbjct: 379 ---MKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKA 435
Query: 135 KVPVD-KVTPSTLPEEVLDFEKFLQQTGGRQGAWD---DYDHQNFVKVRNKHKGKPTFME 190
++ K T EE + ++ L + +Q D + K++ H+ + E
Sbjct: 436 EMDEQIKTIEKTSEEERISLQQELSRV--KQEVVDVMKKSSEEQIAKLQKLHEKELARKE 493
Query: 191 EVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTP 250
+ L + E Q+ K +ALE+ + E ++I + K+QQ+ + +L+ +
Sbjct: 494 QELTKKLQTREREFQEQMK-----VALEKSQSEYLKISQEKEQQESLALEELELQKKAIL 548
Query: 251 VLFHNKQEDNQKQKEEQRKK--------QKLAVEAWKKQKSIEMSMKCASQLKEEE---- 298
NK D Q++ E R + +K E + K + + ++ +E
Sbjct: 549 TESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVM 608
Query: 299 -EKEK------KHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNA 351
EK K KHQ++ KL++L + Y + ++ E EKE K +K
Sbjct: 609 VEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLK----DKEIIF 664
Query: 352 ADEISRFQERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKV 394
I E+ L KL++K + ++ E S+ + KL+E++
Sbjct: 665 QAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEEL 707
Score = 58.9 bits (141), Expect = 9e-09
Identities = 104/464 (22%), Positives = 186/464 (40%), Gaps = 87/464 (18%)
Query: 21 SMLEELENKLIH--SRKT------------ERAKIQQQLAKIHNNVKKLQHQLKDVKPTP 66
++LE N+LI+ S KT K+++ L V +L+ QL+ +
Sbjct: 1226 ALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQ 1285
Query: 67 DFV----EKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRK---IDTWA 119
+ + ++ +EE EN I + K + + E +K N+ A S K I
Sbjct: 1286 NTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLK 1345
Query: 120 LGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQT-------GGRQGAWDDYDH 172
SE A + ++ KV S+L +++ D LQ + YD
Sbjct: 1346 KELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDE 1405
Query: 173 QN----------FVKVRNKHKGKPTFMEEV------LEHLPGKTQDEVQQHEKWYQKF-L 215
+ KV K K + +E+V K Q QH+ ++ +
Sbjct: 1406 EKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQI 1465
Query: 216 ALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQK-QKEEQRKKQKLA 274
LE + KE+ +K E+I LKE+ D NK+ D K + E+ + K +
Sbjct: 1466 QLELKSKEA--------YEKDEQINLLKEELDQ-----QNKRFDCLKGEMEDDKSKME-- 1510
Query: 275 VEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQKK-EQEEFLR 333
KK+ ++E +K SQ E E ++ L +L++Y QQK E +E ++
Sbjct: 1511 ----KKESNLETELK--SQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQ 1564
Query: 334 LEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKI-----------LDRQAKEDE--- 379
+ +E E+ + R A+E E ++ ++ ++ L ++KE+E
Sbjct: 1565 KLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKA 1624
Query: 380 -----KSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKK 418
+S+ +LA+LK K E ++ +L + EE+ KK
Sbjct: 1625 LEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKK 1668
Score = 57.8 bits (138), Expect = 2e-08
Identities = 91/414 (21%), Positives = 167/414 (40%), Gaps = 85/414 (20%)
Query: 38 RAKIQQQLAKIHNNVKKLQHQL----KDVKPTPDFVEKLREMMEEIENAINTFKEEQRLI 93
+ K Q + + N VK+LQ QL K+ + + L+E +++ + K E
Sbjct: 1446 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1505
Query: 94 YEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLD- 152
++ K+E EL + + +I E E D +T T+ E L+
Sbjct: 1506 KSKMEKKESNLETELKSQTARI-------MELE------------DHITQKTIEIESLNE 1546
Query: 153 -FEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWY 211
+ + QQ D +H+ V + L+H +++ + ++
Sbjct: 1547 VLKNYNQQ--------KDIEHKELV--------------QKLQHFQELGEEKDNRVKEAE 1584
Query: 212 QKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQ 271
+K L LE + +TKK++ +K K + L + ++ + E ++K
Sbjct: 1585 EKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKA 1644
Query: 272 KLAVEAWKKQKSIEMSMKCASQLKEEEEKEKK---------HQKERQRQFKLKLLLESYT 322
+ + A KKQ SQ++E+EE+ KK + K ++R+ ++ +L E
Sbjct: 1645 EQKIAAIKKQ--------LLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLK 1696
Query: 323 QQKKEQEEFLRLEKEIREKAEKAEK---------RKNAADEISRFQERDLHKLELKILDR 373
+ Q E L + + + A E+ +K ++IS Q R+L + E K+L R
Sbjct: 1697 SVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQ-RNLTEKE-KLLQR 1754
Query: 374 QAKEDEKS---------QKQRRLAKLKEKVENNVSRDPSRLYKPTKGWEERTKK 418
+E E++ Q Q RL KL E E D S + + EE+ KK
Sbjct: 1755 VGQEKEETVSSHFEMRCQYQERLIKL-EHAEAKQHEDQSMIGHLQEELEEKNKK 1807
Score = 56.6 bits (135), Expect = 4e-08
Identities = 90/427 (21%), Positives = 192/427 (44%), Gaps = 67/427 (15%)
Query: 23 LEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENA 82
LEE EN++ K+ +A I+ + + K+ +Q + + +L++ + E NA
Sbjct: 1299 LEEKENQI----KSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINA 1354
Query: 83 INTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTW------ALGNSETEKAFRAISSKV 136
+ KEE +KE+K E+S++S+++ ++ SE E A ++ +
Sbjct: 1355 VTLMKEE--------LKEKKV---EISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQY 1403
Query: 137 P------VDKVTPSTLPEEVLDFEKF--LQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTF 188
+D+V + + L EK L+Q DD+ ++ F + + K + + T
Sbjct: 1404 DEEKCELLDQVQDLSFKVDTLSKEKISALEQV-------DDWSNK-FSEWKKKAQSRFTQ 1455
Query: 189 MEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTK--KQQKREEIFKLKEKA 246
+ ++ L + Q E++ E + K E I + K + +Q KR + K + +
Sbjct: 1456 HQNTVKEL--QIQLELKSKEAY---------EKDEQINLLKEELDQQNKRFDCLKGEMED 1504
Query: 247 DNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQK 306
D + + K+E N + + + + + + +E QK+IE+ ++K+ +H++
Sbjct: 1505 DKSKM---EKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKE 1561
Query: 307 ERQRQFKLKLLLESYTQQKKEQEE-FLRLEKEIREKAEKAEKRKNAADEIS---RFQERD 362
Q+ + L E + KE EE L LE ++ + E +K + ++ + +E +
Sbjct: 1562 LVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEE 1621
Query: 363 LHKLELKI----------LDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYKPTKGW 412
L LE ++ L R+A++ + K++ L++++EK E S L +
Sbjct: 1622 LKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKL 1681
Query: 413 EERTKKI 419
+ER +++
Sbjct: 1682 QEREREV 1688
Score = 54.7 bits (130), Expect = 2e-07
Identities = 76/396 (19%), Positives = 166/396 (41%), Gaps = 30/396 (7%)
Query: 2 EKDKHSHFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKD 61
E++K + +++ F+ + E + + ++TE + +L+++ KL+ +L
Sbjct: 650 EQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSV 709
Query: 62 VKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKE-EKTTNNELSAISRKIDTWAL 120
+K D +M +E+E ++ K + + +IKE E + A+ +I+ L
Sbjct: 710 LKDQTD------KMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLEL 763
Query: 121 GNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRN 180
E +K + + V L ++ E LQQ + + Y + +
Sbjct: 764 LLKERDKHLKEHQAHV-------ENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKA 816
Query: 181 KHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIF 240
+ +++L+ + Q E QK E IQ+ + QQ ++
Sbjct: 817 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV-QDLMQQLEKQNS 875
Query: 241 KLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEK 300
++++K + ++ +K ED K++E+ ++ + VE K+ I Q++E ++K
Sbjct: 876 EMEQKVKSLTQVYESKLEDGNKEQEQTKQ---ILVE---KENMI-------LQMREGQKK 922
Query: 301 EKK--HQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRF 358
E + QK ++ + +L E Y + K QE+ + K+ ++ ++ K+K E
Sbjct: 923 EIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLK 982
Query: 359 QERDLHKLELKILDRQAKEDEKSQKQRRLAKLKEKV 394
+E + LEL ++Q Q A + + V
Sbjct: 983 KELENTALELSQKEKQFNAKMLEMAQANSAGISDAV 1018
Score = 48.9 bits (115), Expect = 9e-06
Identities = 50/220 (22%), Positives = 108/220 (49%), Gaps = 19/220 (8%)
Query: 194 EHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLF 253
E+L + ++ +Q H++ L +KE++Q ++ Q+ E+I L A+ T ++
Sbjct: 292 ENLLKRCKETIQSHKEQ----CTLLTSEKEALQEQLDERLQELEKIKDL-HMAEKTKLIT 346
Query: 254 HNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEE------EEKEKKHQKE 307
+ N ++ EQ K +A + +++EM + +QL+ + +E + QKE
Sbjct: 347 QLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKE 406
Query: 308 RQRQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLE 367
+ + + L ++ + +K +E +L+ E+ E+ + EK + IS QE L +++
Sbjct: 407 KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE-ERISLQQE--LSRVK 463
Query: 368 LKILDRQAKEDEKSQKQRRLAKLKEKVENNVSRDPSRLYK 407
+++D K E+ ++AKL++ E ++R L K
Sbjct: 464 QEVVDVMKKSSEE-----QIAKLQKLHEKELARKEQELTK 498
Score = 45.4 bits (106), Expect = 1e-04
Identities = 54/252 (21%), Positives = 110/252 (43%), Gaps = 30/252 (11%)
Query: 173 QNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKK----ESIQIW 228
+ ++R++ K T EE+ E + ++ EK EE ++ E +
Sbjct: 382 EEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQI 441
Query: 229 KTKKQQKREEIFKLKE-----KADNTPVLFHNKQEDNQK-----QKEEQRKKQKLAVEAW 278
KT ++ EE L++ K + V+ + +E K +KE RK+Q+L +
Sbjct: 442 KTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQ 501
Query: 279 KKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLK--------LLLESYTQQKKEQEE 330
+++ + MK A + + E + +KE+Q L+ +L ES + + Q+E
Sbjct: 502 TREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQE 561
Query: 331 -------FLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQK 383
L LE + EK+ + K ++ + E++ H E+ ++ + K + +S K
Sbjct: 562 AETYRTRILELESSL-EKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLK 620
Query: 384 QRRLAKLKEKVE 395
++ A EK++
Sbjct: 621 HQQDALWTEKLQ 632
Score = 41.6 bits (96), Expect = 0.001
Identities = 70/387 (18%), Positives = 155/387 (40%), Gaps = 60/387 (15%)
Query: 14 SDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLR 73
++ R E M ++ + L + Q ++ + V L+ +L++ D ++ L
Sbjct: 190 AELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLP 249
Query: 74 EMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAIS 133
++ + E KEE E + E+ T+ L + +++ E +
Sbjct: 250 QLEPQAEVFT---KEENPESDGEPVVEDGTSVKTLETLQQRV-------KRQENLLKRCK 299
Query: 134 SKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVL 193
+ K + L E ++ L D Q K+++ H + T + L
Sbjct: 300 ETIQSHKEQCTLLTSEKEALQEQL-----------DERLQELEKIKDLHMAEKTKLITQL 348
Query: 194 EHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLF 253
++ ++Q E+ K + + E K++ + + K EEI +L+ +
Sbjct: 349 RD----AKNLIEQLEQ--DKGMVIAETKRQMHE----TLEMKEEEIAQLRSR-------I 391
Query: 254 HNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFK 313
++ +E++ K ++ A E + K S ++ EE +K + E Q K
Sbjct: 392 KQMTTQGEELREQKEKSERAAFEELE---------KALSTAQKTEEARRKLKAEMDEQIK 442
Query: 314 LKLLLESYTQQKKEQEEFLRLEKEI-REKAEKAEKRKNAADE----ISRFQERDLHKLEL 368
T +K +EE + L++E+ R K E + K +++E + + E++L + E
Sbjct: 443 --------TIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQ 494
Query: 369 KILDRQAKEDEKSQKQRRLAKLKEKVE 395
++ + + + Q+Q ++A K + E
Sbjct: 495 ELTKKLQTREREFQEQMKVALEKSQSE 521
Score = 39.7 bits (91), Expect = 0.006
Identities = 70/376 (18%), Positives = 155/376 (41%), Gaps = 71/376 (18%)
Query: 40 KIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRL--IYEEL 97
K++ AK H + + H ++++ + E E N + +Q L +++++
Sbjct: 1779 KLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDV 1838
Query: 98 ---IKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFE 154
++E++ T L +++D+ + E + V ++++T +E
Sbjct: 1839 QKTLQEKELTCQILEQKIKELDSCLVRQKEVHR--------VEMEELTSK--------YE 1882
Query: 155 KF--LQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWYQ 212
K LQQ GR + + +N + H +P + + QH
Sbjct: 1883 KLQALQQMDGRNKPTELLE-ENTEEKSKSHLVQPKLLSNM-----------EAQHNDLEF 1930
Query: 213 KFLALEERK----KESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQR 268
K E K KE +++ K + ++E H ++ + K++ +Q
Sbjct: 1931 KLAGAEREKQKLGKEIVRLQKDLRMLRKE----------------HQQELEILKKEYDQE 1974
Query: 269 KKQKLAVEAWKKQKSIEMSMKCASQLKE--EEEKEKKHQKERQRQFKLKLLLESYTQQKK 326
+++K+ KQ+ ++ +K S LK+ E + QKE++ + +K + + +
Sbjct: 1975 REEKI------KQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEA 2028
Query: 327 E-----QEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKS 381
E QEE +L K+I EK + ++ +EI +E + + K+ D Q + +E
Sbjct: 2029 ELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEE---MTAKVRDLQTQLEELQ 2085
Query: 382 QKQRRLAKLKEKVENN 397
+K ++ + +E N+
Sbjct: 2086 KKYQQKLEQEENPGND 2101
Score = 38.1 bits (87), Expect = 0.016
Identities = 62/361 (17%), Positives = 145/361 (40%), Gaps = 49/361 (13%)
Query: 17 RIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMM 76
+I ++EL++ L+ ++ R ++++ +K + ++ LQ KPT E L E
Sbjct: 1850 QILEQKIKELDSCLVRQKEVHRVEMEELTSK-YEKLQALQQMDGRNKPT----ELLEENT 1904
Query: 77 EEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKV 136
EE K + L+ +L+ + +N+L + L +E EK
Sbjct: 1905 EE--------KSKSHLVQPKLLSNMEAQHNDLE--------FKLAGAEREK--------- 1939
Query: 137 PVDKVTPSTLPEEVLDFEKFLQQTGGRQGAW-----DDYDHQNFVKVRNKHKGKPTFMEE 191
L +E++ +K L+ +YD + K++ + +
Sbjct: 1940 -------QKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNS 1992
Query: 192 VLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQ--IWKTKKQQKREEIFKLKEKADNT 249
L+ L + ++ Q E+ + + K + ++ + ++ +++ + + K+ EK D+
Sbjct: 1993 TLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDL 2052
Query: 250 PVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQ 309
+E ++EE K V + Q E+ K +L++EE + +
Sbjct: 2053 KRTAKRYEEILDAREEEMTAK----VRDLQTQLE-ELQKKYQQKLEQEENPGNDNVTIME 2107
Query: 310 RQFKLKLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELK 369
Q +L + K +++EF + ++ +K EK A + ++ +L+ ++
Sbjct: 2108 LQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVGTPYKGGNLYHTDVS 2167
Query: 370 I 370
+
Sbjct: 2168 L 2168
Score = 36.6 bits (83), Expect = 0.047
Identities = 87/435 (20%), Positives = 175/435 (40%), Gaps = 80/435 (18%)
Query: 41 IQQQLAKIHNNVKKLQHQLKD----VKPTPDFVEKLREMMEEIENAIN------TFKEEQ 90
++++ K + +LQ QLK V KL+ +E++E +N TF +EQ
Sbjct: 1097 LKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQ 1156
Query: 91 RLIYEELIKEE-----------KTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVD 139
+ + L +E+ KTT+ E ++ + + F+ +S ++ +
Sbjct: 1157 LVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQ 1216
Query: 140 -----KVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLE 194
K T + L + + + + KV+ K + E+
Sbjct: 1217 LDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEA 1276
Query: 195 HLPGKTQDEVQQHEKWYQKFLALEER----------------KKESIQIWKTKKQQKREE 238
L T+++ + + Q LEE+ +KE++Q +QQ E
Sbjct: 1277 QLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASE 1336
Query: 239 ----IFKL-KEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCA-- 291
I +L KE ++N + K+E +K+ E ++L + Q SI +S K A
Sbjct: 1337 KESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAI 1396
Query: 292 SQLKEEEEKEKKHQKERQRQFKLKL---------LLESYTQ--------QKKEQEEFLRL 334
S L+++ ++EK ++ + K+ LE +KK Q F +
Sbjct: 1397 SSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQH 1456
Query: 335 EKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAK---------EDEKSQKQR 385
+ ++E + E + A E + ++ +L K E LD+Q K ED+KS+ ++
Sbjct: 1457 QNTVKELQIQLELKSKEAYE--KDEQINLLKEE---LDQQNKRFDCLKGEMEDDKSKMEK 1511
Query: 386 RLAKLKEKVENNVSR 400
+ + L+ ++++ +R
Sbjct: 1512 KESNLETELKSQTAR 1526
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 64.7 bits (156), Expect = 2e-10
Identities = 101/449 (22%), Positives = 193/449 (42%), Gaps = 52/449 (11%)
Query: 8 HFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQ--------- 58
H+ K F+I+ + K + + K E KI+ +LAK K+L+ +
Sbjct: 832 HWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKN 891
Query: 59 ------------LKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNN 106
L D + D + K + +E + E++ I EL +++ +
Sbjct: 892 DLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLED 951
Query: 107 ELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEV--LDFEKFLQQTGGRQ 164
E S + + ID L ++ EK A +KV + L E + L EK Q +Q
Sbjct: 952 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1011
Query: 165 GAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQH---EKWYQKFLALEERK 221
D ++ V K K K +E+ ++ L G + E + E+ +K +
Sbjct: 1012 TLDDLQAEEDKVNTLTKAKIK---LEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1068
Query: 222 KESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQ 281
+ESI + +KQQ E++ K + + N +K ED Q + +KK K ++A ++
Sbjct: 1069 QESIMDIENEKQQLDEKLKKKEFEISN----LQSKIEDEQALGIQLQKKIK-ELQARIEE 1123
Query: 282 KSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQ----KKEQEEFLRLEKE 337
E+ + AS+ K E+++ ++ + +L+ + + Q KK + EF ++ ++
Sbjct: 1124 LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD 1183
Query: 338 IRE-----KAEKAEKRKNAADEISRFQER--DLHKLELKILDRQAKEDEKSQKQRRLAKL 390
+ E +A A RK AD ++ E+ +L +++ K+ E EKS+ + + L
Sbjct: 1184 LEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL------EKEKSEMKMEIDDL 1237
Query: 391 KEKVENNVSRDPSRLYKPTKGWEERTKKI 419
VE VS+ L K + E++ ++
Sbjct: 1238 ASNVE-TVSKAKGNLEKMCRTLEDQLSEL 1265
Score = 50.1 bits (118), Expect = 4e-06
Identities = 82/418 (19%), Positives = 190/418 (45%), Gaps = 59/418 (14%)
Query: 16 FRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVK---KLQHQLKDVKPTPDFVEKL 72
F+I+++ E L+ + + K E +QQ+++ + + K H+L+ +K + ++
Sbjct: 1488 FKIKNAYEESLDQ--LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVE--QEK 1543
Query: 73 REMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAI 132
E+ +E A + + E+ ++++ + N S + RKI A + E ++ R
Sbjct: 1544 CELQAALEEAEASLEHEEG----KILRIQLELNQVKSEVDRKI---AEKDEEIDQLKR-- 1594
Query: 133 SSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYD----HQNFVKVR--NKHKGKP 186
+ + + + STL E+ ++ +G ++ + H N + ++
Sbjct: 1595 -NHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQ 1653
Query: 187 TFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQ---------IWKTKKQQK-- 235
+++ HL D+ + ++ ++ LA+ ER+ +Q + +T++ +K
Sbjct: 1654 GILKDTQIHL-----DDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIA 1708
Query: 236 REEIFKLKEKAD-----NTPVLFHNKQED---NQKQKEEQRKKQKLAVEAWKKQKSIEMS 287
+E+ E+ NT ++ K+ + +Q Q E + Q+ K +K+I +
Sbjct: 1709 EQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDA 1768
Query: 288 MKCASQLKEEE------EKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIRE- 340
A +LK+E+ E+ KK+ ++ + +L+L K +++ +LE +RE
Sbjct: 1769 AMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVREL 1828
Query: 341 KAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKS--QKQRRLAKLKEKVEN 396
+ E ++K A+ + ++ H+ +K L Q +ED K+ + Q + KL+ KV++
Sbjct: 1829 EGEVESEQKRNAEAVKGLRK---HERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1883
Score = 46.6 bits (109), Expect = 5e-05
Identities = 70/377 (18%), Positives = 149/377 (39%), Gaps = 30/377 (7%)
Query: 38 RAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEEL 97
+ K++++ +++ + L ++ V +EK+ +E+ + + + +EEQ+ + +L
Sbjct: 1220 KQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDL 1279
Query: 98 IKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFL 157
+ E SR++D S+ + +A + ++ K L EE+
Sbjct: 1280 TAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELK---RQLEEEIKAKNALA 1336
Query: 158 QQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWY-----Q 212
Q + D D +R +++ + E L+ K EV Q Y Q
Sbjct: 1337 H---ALQSSRHDCD-----LLREQYEEEQESKAE-LQRALSKANTEVAQWRTKYETDAIQ 1387
Query: 213 KFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQK 272
+ LEE KK+ Q + Q E + + K + Q + + + +
Sbjct: 1388 RTEELEEAKKKLAQ----RLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNA 1443
Query: 273 LAVEAWKKQKSI-----EMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQ--- 324
KKQ++ E KC E E +K+ + FK+K E Q
Sbjct: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503
Query: 325 -KKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQK 383
K+E + + ++ E+ + KR + ++I + E++ +L+ + + +A + + K
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK 1563
Query: 384 QRRLAKLKEKVENNVSR 400
R+ +V++ V R
Sbjct: 1564 ILRIQLELNQVKSEVDR 1580
Score = 38.9 bits (89), Expect = 0.010
Identities = 75/389 (19%), Positives = 158/389 (40%), Gaps = 59/389 (15%)
Query: 12 QKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEK 71
+++ RI SM L+ ++ R K K+ ++ +++ QL
Sbjct: 1593 KRNHIRIVESMQSTLDAEIRSRNDAIRLK-----KKMEGDLNEMEIQLNHAN-------- 1639
Query: 72 LREMMEEIENAINT--FKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAF 129
R E + N NT ++ ++ ++ ++ ++ +L+ + R+ + L +E E+
Sbjct: 1640 -RMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRAN---LLQAEIEELR 1695
Query: 130 RAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFM 189
+ K+ +E+LD + +Q QN + K K +
Sbjct: 1696 ATLEQTERSRKIAE----QELLDASERVQLL----------HTQNTSLINTKKK-----L 1736
Query: 190 EEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNT 249
E + + G+ +D +Q+ EE+ K++I T EE LK++ D +
Sbjct: 1737 ETDISQMQGEMEDILQEARN-------AEEKAKKAI----TDAAMMAEE---LKKEQDTS 1782
Query: 250 PVLFHNKQEDNQKQKEEQRK---KQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQK 306
L K+ Q K+ Q + ++LA++ KKQ I+ +L+ E E E+K
Sbjct: 1783 AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQ--IQKLEARVRELEGEVESEQKRNA 1840
Query: 307 ERQRQFKL--KLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLH 364
E + + + + E Q +++++ LRL+ + + K + K A+E +L
Sbjct: 1841 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900
Query: 365 KLELKILDRQAKEDEKSQKQRRLAKLKEK 393
K + + E+ + ++ KL+ K
Sbjct: 1901 KFRKLQHELEEAEERADIAESQVNKLRVK 1929
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 64.7 bits (156), Expect = 2e-10
Identities = 101/449 (22%), Positives = 193/449 (42%), Gaps = 52/449 (11%)
Query: 8 HFYNQKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQ--------- 58
H+ K F+I+ + K + + K E KI+ +LAK K+L+ +
Sbjct: 832 HWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKN 891
Query: 59 ------------LKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEELIKEEKTTNN 106
L D + D + K + +E + E++ I EL +++ +
Sbjct: 892 DLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLED 951
Query: 107 ELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEV--LDFEKFLQQTGGRQ 164
E S + + ID L ++ EK A +KV + L E + L EK Q +Q
Sbjct: 952 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1011
Query: 165 GAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQH---EKWYQKFLALEERK 221
D ++ V K K K +E+ ++ L G + E + E+ +K +
Sbjct: 1012 TLDDLQAEEDKVNTLTKAKIK---LEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLA 1068
Query: 222 KESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQKLAVEAWKKQ 281
+ESI + +KQQ E++ K + + N +K ED Q + +KK K ++A ++
Sbjct: 1069 QESIMDIENEKQQLDEKLKKKEFEISN----LQSKIEDEQALGIQLQKKIK-ELQARIEE 1123
Query: 282 KSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQ----KKEQEEFLRLEKE 337
E+ + AS+ K E+++ ++ + +L+ + + Q KK + EF ++ ++
Sbjct: 1124 LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRD 1183
Query: 338 IRE-----KAEKAEKRKNAADEISRFQER--DLHKLELKILDRQAKEDEKSQKQRRLAKL 390
+ E +A A RK AD ++ E+ +L +++ K+ E EKS+ + + L
Sbjct: 1184 LEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL------EKEKSEMKMEIDDL 1237
Query: 391 KEKVENNVSRDPSRLYKPTKGWEERTKKI 419
VE VS+ L K + E++ ++
Sbjct: 1238 ASNVE-TVSKAKGNLEKMCRTLEDQLSEL 1265
Score = 50.1 bits (118), Expect = 4e-06
Identities = 82/418 (19%), Positives = 190/418 (45%), Gaps = 59/418 (14%)
Query: 16 FRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVK---KLQHQLKDVKPTPDFVEKL 72
F+I+++ E L+ + + K E +QQ+++ + + K H+L+ +K + ++
Sbjct: 1488 FKIKNAYEESLDQ--LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVE--QEK 1543
Query: 73 REMMEEIENAINTFKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAFRAI 132
E+ +E A + + E+ ++++ + N S + RKI A + E ++ R
Sbjct: 1544 CELQAALEEAEASLEHEEG----KILRIQLELNQVKSEVDRKI---AEKDEEIDQLKR-- 1594
Query: 133 SSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYD----HQNFVKVR--NKHKGKP 186
+ + + + STL E+ ++ +G ++ + H N + ++
Sbjct: 1595 -NHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQ 1653
Query: 187 TFMEEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQ---------IWKTKKQQK-- 235
+++ HL D+ + ++ ++ LA+ ER+ +Q + +T++ +K
Sbjct: 1654 GILKDTQIHL-----DDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIA 1708
Query: 236 REEIFKLKEKAD-----NTPVLFHNKQED---NQKQKEEQRKKQKLAVEAWKKQKSIEMS 287
+E+ E+ NT ++ K+ + +Q Q E + Q+ K +K+I +
Sbjct: 1709 EQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDA 1768
Query: 288 MKCASQLKEEE------EKEKKHQKERQRQFKLKLLLESYTQQKKEQEEFLRLEKEIRE- 340
A +LK+E+ E+ KK+ ++ + +L+L K +++ +LE +RE
Sbjct: 1769 AMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVREL 1828
Query: 341 KAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKS--QKQRRLAKLKEKVEN 396
+ E ++K A+ + ++ H+ +K L Q +ED K+ + Q + KL+ KV++
Sbjct: 1829 EGEVESEQKRNAEAVKGLRK---HERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1883
Score = 46.6 bits (109), Expect = 5e-05
Identities = 70/377 (18%), Positives = 149/377 (39%), Gaps = 30/377 (7%)
Query: 38 RAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEKLREMMEEIENAINTFKEEQRLIYEEL 97
+ K++++ +++ + L ++ V +EK+ +E+ + + + +EEQ+ + +L
Sbjct: 1220 KQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDL 1279
Query: 98 IKEEKTTNNELSAISRKIDTWALGNSETEKAFRAISSKVPVDKVTPSTLPEEVLDFEKFL 157
+ E SR++D S+ + +A + ++ K L EE+
Sbjct: 1280 TAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELK---RQLEEEIKAKNALA 1336
Query: 158 QQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFMEEVLEHLPGKTQDEVQQHEKWY-----Q 212
Q + D D +R +++ + E L+ K EV Q Y Q
Sbjct: 1337 H---ALQSSRHDCD-----LLREQYEEEQESKAE-LQRALSKANTEVAQWRTKYETDAIQ 1387
Query: 213 KFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNTPVLFHNKQEDNQKQKEEQRKKQK 272
+ LEE KK+ Q + Q E + + K + Q + + + +
Sbjct: 1388 RTEELEEAKKKLAQ----RLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNA 1443
Query: 273 LAVEAWKKQKSI-----EMSMKCASQLKEEEEKEKKHQKERQRQFKLKLLLESYTQQ--- 324
KKQ++ E KC E E +K+ + FK+K E Q
Sbjct: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLET 1503
Query: 325 -KKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQAKEDEKSQK 383
K+E + + ++ E+ + KR + ++I + E++ +L+ + + +A + + K
Sbjct: 1504 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGK 1563
Query: 384 QRRLAKLKEKVENNVSR 400
R+ +V++ V R
Sbjct: 1564 ILRIQLELNQVKSEVDR 1580
Score = 38.9 bits (89), Expect = 0.010
Identities = 75/389 (19%), Positives = 158/389 (40%), Gaps = 59/389 (15%)
Query: 12 QKSDFRIEHSMLEELENKLIHSRKTERAKIQQQLAKIHNNVKKLQHQLKDVKPTPDFVEK 71
+++ RI SM L+ ++ R K K+ ++ +++ QL
Sbjct: 1593 KRNHIRIVESMQSTLDAEIRSRNDAIRLK-----KKMEGDLNEMEIQLNHAN-------- 1639
Query: 72 LREMMEEIENAINT--FKEEQRLIYEELIKEEKTTNNELSAISRKIDTWALGNSETEKAF 129
R E + N NT ++ ++ ++ ++ ++ +L+ + R+ + L +E E+
Sbjct: 1640 -RMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRAN---LLQAEIEELR 1695
Query: 130 RAISSKVPVDKVTPSTLPEEVLDFEKFLQQTGGRQGAWDDYDHQNFVKVRNKHKGKPTFM 189
+ K+ +E+LD + +Q QN + K K +
Sbjct: 1696 ATLEQTERSRKIAE----QELLDASERVQLL----------HTQNTSLINTKKK-----L 1736
Query: 190 EEVLEHLPGKTQDEVQQHEKWYQKFLALEERKKESIQIWKTKKQQKREEIFKLKEKADNT 249
E + + G+ +D +Q+ EE+ K++I T EE LK++ D +
Sbjct: 1737 ETDISQMQGEMEDILQEARN-------AEEKAKKAI----TDAAMMAEE---LKKEQDTS 1782
Query: 250 PVLFHNKQEDNQKQKEEQRK---KQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQK 306
L K+ Q K+ Q + ++LA++ KKQ I+ +L+ E E E+K
Sbjct: 1783 AHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQ--IQKLEARVRELEGEVESEQKRNA 1840
Query: 307 ERQRQFKL--KLLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLH 364
E + + + + E Q +++++ LRL+ + + K + K A+E +L
Sbjct: 1841 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900
Query: 365 KLELKILDRQAKEDEKSQKQRRLAKLKEK 393
K + + E+ + ++ KL+ K
Sbjct: 1901 KFRKLQHELEEAEERADIAESQVNKLRVK 1929
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,610,860
Number of Sequences: 37866
Number of extensions: 902424
Number of successful extensions: 22891
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 599
Number of HSP's successfully gapped in prelim test: 1169
Number of HSP's that attempted gapping in prelim test: 6150
Number of HSP's gapped (non-prelim): 6995
length of query: 446
length of database: 18,247,518
effective HSP length: 105
effective length of query: 341
effective length of database: 14,271,588
effective search space: 4866611508
effective search space used: 4866611508
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.