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Search of human proteins with 145275208
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145275208 myosin IIIA [Homo sapiens]
(1616 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145275208 myosin IIIA [Homo sapiens] 3237 0.0
gi|134288892 myosin IIIB isoform 2 [Homo sapiens] 1466 0.0
gi|134288915 myosin IIIB isoform 1 [Homo sapiens] 1452 0.0
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 507 e-143
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 507 e-143
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 507 e-143
gi|122937512 myosin VIIB [Homo sapiens] 491 e-138
gi|118402590 myosin XV [Homo sapiens] 476 e-134
gi|154354979 myosin X [Homo sapiens] 471 e-132
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens] 442 e-124
gi|153945715 myosin VC [Homo sapiens] 430 e-120
gi|156104908 myosin heavy chain 6 [Homo sapiens] 426 e-119
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 422 e-117
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 417 e-116
gi|122937345 myosin VB [Homo sapiens] 416 e-116
gi|215982794 myosin VA isoform 2 [Homo sapiens] 415 e-115
gi|215982791 myosin VA isoform 1 [Homo sapiens] 415 e-115
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 412 e-114
gi|156119615 myosin IXA [Homo sapiens] 412 e-114
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 411 e-114
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 410 e-114
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 410 e-114
gi|124494247 myosin IC isoform b [Homo sapiens] 409 e-113
gi|124494238 myosin IC isoform a [Homo sapiens] 409 e-113
gi|124494240 myosin IC isoform c [Homo sapiens] 409 e-113
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 406 e-113
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 406 e-112
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 406 e-112
gi|194328685 myosin IB isoform 1 [Homo sapiens] 405 e-112
gi|240120050 myosin IB isoform 1 [Homo sapiens] 405 e-112
>gi|145275208 myosin IIIA [Homo sapiens]
Length = 1616
Score = 3237 bits (8393), Expect = 0.0
Identities = 1616/1616 (100%), Positives = 1616/1616 (100%)
Query: 1 MFPLIGKTIIFDNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDE 60
MFPLIGKTIIFDNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDE
Sbjct: 1 MFPLIGKTIIFDNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDE 60
Query: 61 EIEAEYNILKALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGE 120
EIEAEYNILKALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGE
Sbjct: 61 EIEAEYNILKALSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGE 120
Query: 121 RMSEPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRH 180
RMSEPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRH
Sbjct: 121 RMSEPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRH 180
Query: 181 RRNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALF 240
RRNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALF
Sbjct: 181 RRNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALF 240
Query: 241 KIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQ 300
KIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQ
Sbjct: 241 KIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQ 300
Query: 301 LTEFIGIHQCMGGTEKARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEK 360
LTEFIGIHQCMGGTEKARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEK
Sbjct: 301 LTEFIGIHQCMGGTEKARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEK 360
Query: 361 CYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMIT 420
CYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMIT
Sbjct: 361 CYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMIT 420
Query: 421 YNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRTLQEKILQVNNLVEAFGNACTII 480
YNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRTLQEKILQVNNLVEAFGNACTII
Sbjct: 421 YNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRTLQEKILQVNNLVEAFGNACTII 480
Query: 481 NDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKK 540
NDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKK
Sbjct: 481 NDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKK 540
Query: 541 KLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSI 600
KLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSI
Sbjct: 541 KLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSI 600
Query: 601 LAAILNVGNIEFSSVATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGE 660
LAAILNVGNIEFSSVATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGE
Sbjct: 601 LAAILNVGNIEFSSVATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGE 660
Query: 661 TIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFG 720
TIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFG
Sbjct: 661 TIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFG 720
Query: 721 FENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFL 780
FENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFL
Sbjct: 721 FENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFL 780
Query: 781 QKPMGLLSLLDEESRFPKATDQTLVEKFEGNLKSQYFWRPKRMELSFGIHHYAGKVLYNA 840
QKPMGLLSLLDEESRFPKATDQTLVEKFEGNLKSQYFWRPKRMELSFGIHHYAGKVLYNA
Sbjct: 781 QKPMGLLSLLDEESRFPKATDQTLVEKFEGNLKSQYFWRPKRMELSFGIHHYAGKVLYNA 840
Query: 841 SGFLAKNRDTLPTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKL 900
SGFLAKNRDTLPTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKL
Sbjct: 841 SGFLAKNRDTLPTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKL 900
Query: 901 INLAKGDTGEATRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQA 960
INLAKGDTGEATRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQA
Sbjct: 901 INLAKGDTGEATRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQA 960
Query: 961 RKYDKEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCA 1020
RKYDKEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCA
Sbjct: 961 RKYDKEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCA 1020
Query: 1021 TILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQE 1080
TILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQE
Sbjct: 1021 TILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQE 1080
Query: 1081 KRKESAIIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQ 1140
KRKESAIIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQ
Sbjct: 1081 KRKESAIIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQ 1140
Query: 1141 AENAISANERFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEV 1200
AENAISANERFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEV
Sbjct: 1141 AENAISANERFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEV 1200
Query: 1201 KQEFYLVGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLER 1260
KQEFYLVGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLER
Sbjct: 1201 KQEFYLVGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLER 1260
Query: 1261 KAISERPSYPVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAPICSQE 1320
KAISERPSYPVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAPICSQE
Sbjct: 1261 KAISERPSYPVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAPICSQE 1320
Query: 1321 EGRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIV 1380
EGRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIV
Sbjct: 1321 EGRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIV 1380
Query: 1381 TTPTEVARNTHNLYSYPTKHEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSEEYF 1440
TTPTEVARNTHNLYSYPTKHEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSEEYF
Sbjct: 1381 TTPTEVARNTHNLYSYPTKHEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSEEYF 1440
Query: 1441 ILQKKLNEMILSQQLKSLYLGVSHHKPINRRVSSQQCLSGVCKGEEPKILRPPRRPRKPK 1500
ILQKKLNEMILSQQLKSLYLGVSHHKPINRRVSSQQCLSGVCKGEEPKILRPPRRPRKPK
Sbjct: 1441 ILQKKLNEMILSQQLKSLYLGVSHHKPINRRVSSQQCLSGVCKGEEPKILRPPRRPRKPK 1500
Query: 1501 TLNNPEDSTYYYLLHKSIQEEKRRPRKDSQGKLLDLEDFYYKEFLPSRSGPKEHSPSLRE 1560
TLNNPEDSTYYYLLHKSIQEEKRRPRKDSQGKLLDLEDFYYKEFLPSRSGPKEHSPSLRE
Sbjct: 1501 TLNNPEDSTYYYLLHKSIQEEKRRPRKDSQGKLLDLEDFYYKEFLPSRSGPKEHSPSLRE 1560
Query: 1561 RRPQQELQNQCIKANERCWAAESPEKEEEREPAANPYDFRRLLRKTSQRRRLVQQS 1616
RRPQQELQNQCIKANERCWAAESPEKEEEREPAANPYDFRRLLRKTSQRRRLVQQS
Sbjct: 1561 RRPQQELQNQCIKANERCWAAESPEKEEEREPAANPYDFRRLLRKTSQRRRLVQQS 1616
>gi|134288892 myosin IIIB isoform 2 [Homo sapiens]
Length = 1341
Score = 1466 bits (3796), Expect = 0.0
Identities = 718/1109 (64%), Positives = 886/1109 (79%), Gaps = 1/1109 (0%)
Query: 12 DNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKA 71
++ PDP+DTWEI ETIGKGTYGKV+KV NK++G AAVKILDP+ D+DEEIEAEYNIL+
Sbjct: 18 ESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMDEEIEAEYNILQF 77
Query: 72 LSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYIL 131
L +HPNVV+FYG+++K D G +LWLVLELC+GGSVT+LVKG L+ G+R+ E +I+YIL
Sbjct: 78 LPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYIL 137
Query: 132 HEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFW 191
+ AL+GLQHLHNN+ IHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTR RRNTSVGTPFW
Sbjct: 138 YGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFW 197
Query: 192 MAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPKLR 251
MAPEVIACEQQ D++YDARCD WSLGITAIELGDGDPPL D+HP++ LFKIPRNPPP L
Sbjct: 198 MAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLL 257
Query: 252 QPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQLTEFIGIHQCM 311
PE W EFN FIS+CL KD+E+RP+V+ LL H FI + GK + LQKQL + + +
Sbjct: 258 HPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLAKVLQDQKHQ 317
Query: 312 GGTEKARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYV 371
K R ER+HT++ + DDL LE+LDE+T+ QL+K Y+ IY YV
Sbjct: 318 NPVAKTRHERMHTRRPYHVEDAEKYCLE-DDLVNLEVLDEDTIIHQLQKRYADLLIYTYV 376
Query: 372 GDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISG 431
GDILIALNPFQ+L +YS + S+LY G KR ++PPHIFA AD YQ M+T + DQCIVISG
Sbjct: 377 GDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISG 436
Query: 432 ESGAGKTENAHLLVQQLTVLGKANNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYL 491
ESG+GKTE+AHL+VQ LT LGKANN+TL+EKILQVN+LVEAFGN+CT INDNSSRFGKYL
Sbjct: 437 ESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYL 496
Query: 492 EMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENK 551
EM FT +G V+GA+ISEYLLEKSRVI QA EKNFHIFYYIYAGL +KKL+ ++LPE K
Sbjct: 497 EMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEK 556
Query: 552 PPRYLQNDHLRTVQDIMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIE 611
PPRY+ ++ R + DI + Y+ Q+E I+ CF++IGFT +++ S+Y ILA ILN+GNIE
Sbjct: 557 PPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIE 616
Query: 612 FSSVATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKA 671
F++++++HQ DKS + N AL+N AS+LCI +ELQEALTSHCVVTRGETIIR NTV++A
Sbjct: 617 FAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRA 676
Query: 672 TDVRDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQ 731
DVRDAM+K LYGRLFSWIVN IN+LL+ D + G +++GILDIFGFENF++NSFEQ
Sbjct: 677 ADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQ 736
Query: 732 LCINIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLD 791
LCINIANEQIQYY+NQHVFA EQ EY NE +DA +EYEDN PLLDMFLQKP+GLL+LLD
Sbjct: 737 LCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLD 796
Query: 792 EESRFPKATDQTLVEKFEGNLKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTL 851
EESRFP+ATDQTLV+KFE NL+ +YFWRPK +EL FGI HYAGKVLY+ASG L KNRDTL
Sbjct: 797 EESRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTL 856
Query: 852 PTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEA 911
P D+V++LR+S+N +++QL + PLTKTGNL ++ + + AK DT E
Sbjct: 857 PADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEV 916
Query: 912 TRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQ 971
RH ETTNMK QTVASYFRYSLMDLLSKMVVGQPHFVRCIKPN +R+A ++ +E+VL Q
Sbjct: 917 IRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQ 976
Query: 972 LRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGLDNW 1031
LR TGILET IRR G+SHRILF F+KRYY L + + + P S ++C ILEK+ LD+W
Sbjct: 977 LRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRLDHW 1036
Query: 1032 ALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQS 1091
LGKTKVFLKYYHVEQLNL+ +E I +++++QA + +L +RRY+K++EKR++ AI IQS
Sbjct: 1037 VLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKGAIAIQS 1096
Query: 1092 AARGHLVRKQRKEIVDMKNTAVTTIQTSD 1120
A RG+ R++ K+I + +N + Q D
Sbjct: 1097 AWRGYDARRKFKKISNRRNESAAHNQAGD 1125
Score = 61.2 bits (147), Expect = 8e-09
Identities = 68/248 (27%), Positives = 107/248 (43%), Gaps = 40/248 (16%)
Query: 1341 QAQEEEDKAAVFIQSKYRGYKRRQQLRK---DKMSSFKHQRIVTTPTE-------VARNT 1390
+ +E+ +K A+ IQS +RGY R++ +K + S H + T + VA T
Sbjct: 1082 KVREKREKGAIAIQSAWRGYDARRKFKKISNRRNESAAHNQAGDTSNQSSGPHSPVAAGT 1141
Query: 1391 HNLY-----SYPTKHE--------------EINNIKKKDNKDSKATSEREACGLAIFSKQ 1431
S P H+ E NN + + + +S A +E+ A Q
Sbjct: 1142 RGSAEVQDCSEPGDHKVLRGSVHRRSHSQAESNNGRTQTSSNSPAVTEKNGHSQA----Q 1197
Query: 1432 ISKLSEEYFILQKKLNEMILSQQLKSLYLGVSHHKPINRRVS--SQQCLSGVCKGEEPKI 1489
S + F + + + L S + H P + +S G G K
Sbjct: 1198 SSPKGCDIFAGHANKHSVSGTDLLSSR---ICHPAPDQQGLSLWGAPQKPGSENGLAQKH 1254
Query: 1490 LRPPRRPRKPKTLNNPEDSTYYYLLHKSI--QEEKRRPRKDSQGKLLDLEDFYYKEFLPS 1547
P RR ++PK L++PED+ YY L+ ++ Q KR+PRK Q K+LD ED YYK P
Sbjct: 1255 RTPRRRCQQPKMLSSPEDTMYYNQLNGTLEYQGSKRKPRKLGQIKVLDGEDEYYKSLSPV 1314
Query: 1548 RSGPKEHS 1555
P+E++
Sbjct: 1315 DCIPEENN 1322
>gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
Length = 1314
Score = 1452 bits (3759), Expect = 0.0
Identities = 709/1080 (65%), Positives = 870/1080 (80%), Gaps = 1/1080 (0%)
Query: 12 DNFPDPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKA 71
++ PDP+DTWEI ETIGKGTYGKV+KV NK++G AAVKILDP+ D+DEEIEAEYNIL+
Sbjct: 18 ESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMDEEIEAEYNILQF 77
Query: 72 LSDHPNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYIL 131
L +HPNVV+FYG+++K D G +LWLVLELC+GGSVT+LVKG L+ G+R+ E +I+YIL
Sbjct: 78 LPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYIL 137
Query: 132 HEALMGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFW 191
+ AL+GLQHLHNN+ IHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTR RRNTSVGTPFW
Sbjct: 138 YGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFW 197
Query: 192 MAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPKLR 251
MAPEVIACEQQ D++YDARCD WSLGITAIELGDGDPPL D+HP++ LFKIPRNPPP L
Sbjct: 198 MAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLL 257
Query: 252 QPELWSAEFNDFISKCLTKDYEKRPTVSELLQHKFITQIEGKDVMLQKQLTEFIGIHQCM 311
PE W EFN FIS+CL KD+E+RP+V+ LL H FI + GK + LQKQL + + +
Sbjct: 258 HPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLAKVLQDQKHQ 317
Query: 312 GGTEKARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYV 371
K R ER+HT++ + DDL LE+LDE+T+ QL+K Y+ IY YV
Sbjct: 318 NPVAKTRHERMHTRRPYHVEDAEKYCLE-DDLVNLEVLDEDTIIHQLQKRYADLLIYTYV 376
Query: 372 GDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISG 431
GDILIALNPFQ+L +YS + S+LY G KR ++PPHIFA AD YQ M+T + DQCIVISG
Sbjct: 377 GDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISG 436
Query: 432 ESGAGKTENAHLLVQQLTVLGKANNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYL 491
ESG+GKTE+AHL+VQ LT LGKANN+TL+EKILQVN+LVEAFGN+CT INDNSSRFGKYL
Sbjct: 437 ESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYL 496
Query: 492 EMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENK 551
EM FT +G V+GA+ISEYLLEKSRVI QA EKNFHIFYYIYAGL +KKL+ ++LPE K
Sbjct: 497 EMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEK 556
Query: 552 PPRYLQNDHLRTVQDIMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIE 611
PPRY+ ++ R + DI + Y+ Q+E I+ CF++IGFT +++ S+Y ILA ILN+GNIE
Sbjct: 557 PPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIE 616
Query: 612 FSSVATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKA 671
F++++++HQ DKS + N AL+N AS+LCI +ELQEALTSHCVVTRGETIIR NTV++A
Sbjct: 617 FAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRA 676
Query: 672 TDVRDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQ 731
DVRDAM+K LYGRLFSWIVN IN+LL+ D + G +++GILDIFGFENF++NSFEQ
Sbjct: 677 ADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQ 736
Query: 732 LCINIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLD 791
LCINIANEQIQYY+NQHVFA EQ EY NE +DA +EYEDN PLLDMFLQKP+GLL+LLD
Sbjct: 737 LCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLD 796
Query: 792 EESRFPKATDQTLVEKFEGNLKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTL 851
EESRFP+ATDQTLV+KFE NL+ +YFWRPK +EL FGI HYAGKVLY+ASG L KNRDTL
Sbjct: 797 EESRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTL 856
Query: 852 PTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEA 911
P D+V++LR+S+N +++QL + PLTKTGNL ++ + + AK DT E
Sbjct: 857 PADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTLEV 916
Query: 912 TRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQ 971
RH ETTNMK QTVASYFRYSLMDLLSKMVVGQPHFVRCIKPN +R+A ++ +E+VL Q
Sbjct: 917 IRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQ 976
Query: 972 LRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGLDNW 1031
LR TGILET IRR G+SHRILF F+KRYY L + + + P S ++C ILEK+ LD+W
Sbjct: 977 LRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRLDHW 1036
Query: 1032 ALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQS 1091
LGKTKVFLKYYHVEQLNL+ +E I +++++QA + +L +RRY+K++EKR++ AI IQS
Sbjct: 1037 VLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKGAIAIQS 1096
Score = 55.1 bits (131), Expect = 5e-07
Identities = 30/66 (45%), Positives = 43/66 (65%), Gaps = 2/66 (3%)
Query: 1492 PPRRPRKPKTLNNPEDSTYYYLLHKSI--QEEKRRPRKDSQGKLLDLEDFYYKEFLPSRS 1549
P RR ++PK L++PED+ YY L+ ++ Q KR+PRK Q K+LD ED YYK P
Sbjct: 1230 PRRRCQQPKMLSSPEDTMYYNQLNGTLEYQGSKRKPRKLGQIKVLDGEDEYYKSLSPVDC 1289
Query: 1550 GPKEHS 1555
P+E++
Sbjct: 1290 IPEENN 1295
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 507 bits (1306), Expect = e-143
Identities = 307/775 (39%), Positives = 440/775 (56%), Gaps = 60/775 (7%)
Query: 335 SNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKL 394
+++ V+D+ L L+E + L Y IY Y G IL+A+NP+Q L +YS +H +
Sbjct: 62 TSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQ 121
Query: 395 YIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKA 454
Y K PPHIFA+AD Y +M + DQC +ISGESGAGKTE+ L++Q L +
Sbjct: 122 YTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS-G 180
Query: 455 NNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKS 514
+ +++++L+ ++EAFGNA TI NDNSSRFGKY+++ F GA+ GA+I +YLLEKS
Sbjct: 181 QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240
Query: 515 RVIHQAIGEKNFHIFYYIYAGLAE--KKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSF 572
RV QA+ E+N+H+FY + G++E KKKL L + YL + T + +++
Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLG---LGQASDYNYLAMGNCITCEGRVDSQ- 296
Query: 573 YKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTAL 632
+Y I KV+ FT + I +LAAIL++GN+++ + E+ +D + +L
Sbjct: 297 ---EYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFEN-LDACEVLFSPSL 352
Query: 633 ENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVN 692
ASLL + +L LTS ++TRGET+ P + E+A DVRDA K +YGRLF WIV+
Sbjct: 353 ATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVD 412
Query: 693 CINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAW 752
IN+ + S SIG+LDIFGFENF NSFEQLCIN ANE +Q ++ +HVF
Sbjct: 413 KINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKL 472
Query: 753 EQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKF--EG 810
EQ EY E +D IE+ DN LDM KPM ++SL+DEES+FPK TD T++ K +
Sbjct: 473 EQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQH 532
Query: 811 NLKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQL 870
L + Y E FGI+H+AG V Y GFL KNRDTL DI+ L+ SS N I+Q+
Sbjct: 533 KLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQI 592
Query: 871 VNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYF 930
++A G T ++ T++S F
Sbjct: 593 FQ----------------------------ADVAMG----------AETRKRSPTLSSQF 614
Query: 931 RYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSH 990
+ SL L+ + QP FVRCIKPN ++ +D+ + QLRY+G++ET RIRR G+
Sbjct: 615 KRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPI 674
Query: 991 RILFANFIKRYYLLC--YKSSEEPRMSPDTCATILEK--AGLDNWALGKTKVFLKYYHVE 1046
R F F++RY +L K + + TC + E D+W +GKTK+FLK +H
Sbjct: 675 RYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDM 734
Query: 1047 QLNLMRKEAI-DKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRK 1100
L + R +AI D++IL+Q +R F + K+ K +A +IQ RGH RK
Sbjct: 735 LLEVERDKAITDRVILLQKVIRGFKDRSNFLKL----KNAATLIQRHWRGHNCRK 785
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 507 bits (1306), Expect = e-143
Identities = 307/775 (39%), Positives = 440/775 (56%), Gaps = 60/775 (7%)
Query: 335 SNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKL 394
+++ V+D+ L L+E + L Y IY Y G IL+A+NP+Q L +YS +H +
Sbjct: 62 TSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQ 121
Query: 395 YIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKA 454
Y K PPHIFA+AD Y +M + DQC +ISGESGAGKTE+ L++Q L +
Sbjct: 122 YTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS-G 180
Query: 455 NNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKS 514
+ +++++L+ ++EAFGNA TI NDNSSRFGKY+++ F GA+ GA+I +YLLEKS
Sbjct: 181 QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240
Query: 515 RVIHQAIGEKNFHIFYYIYAGLAE--KKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSF 572
RV QA+ E+N+H+FY + G++E KKKL L + YL + T + +++
Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLG---LGQASDYNYLAMGNCITCEGRVDSQ- 296
Query: 573 YKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTAL 632
+Y I KV+ FT + I +LAAIL++GN+++ + E+ +D + +L
Sbjct: 297 ---EYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFEN-LDACEVLFSPSL 352
Query: 633 ENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVN 692
ASLL + +L LTS ++TRGET+ P + E+A DVRDA K +YGRLF WIV+
Sbjct: 353 ATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVD 412
Query: 693 CINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAW 752
IN+ + S SIG+LDIFGFENF NSFEQLCIN ANE +Q ++ +HVF
Sbjct: 413 KINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKL 472
Query: 753 EQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKF--EG 810
EQ EY E +D IE+ DN LDM KPM ++SL+DEES+FPK TD T++ K +
Sbjct: 473 EQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQH 532
Query: 811 NLKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQL 870
L + Y E FGI+H+AG V Y GFL KNRDTL DI+ L+ SS N I+Q+
Sbjct: 533 KLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQI 592
Query: 871 VNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYF 930
++A G T ++ T++S F
Sbjct: 593 FQ----------------------------ADVAMG----------AETRKRSPTLSSQF 614
Query: 931 RYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSH 990
+ SL L+ + QP FVRCIKPN ++ +D+ + QLRY+G++ET RIRR G+
Sbjct: 615 KRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPI 674
Query: 991 RILFANFIKRYYLLC--YKSSEEPRMSPDTCATILEK--AGLDNWALGKTKVFLKYYHVE 1046
R F F++RY +L K + + TC + E D+W +GKTK+FLK +H
Sbjct: 675 RYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDM 734
Query: 1047 QLNLMRKEAI-DKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRK 1100
L + R +AI D++IL+Q +R F + K+ K +A +IQ RGH RK
Sbjct: 735 LLEVERDKAITDRVILLQKVIRGFKDRSNFLKL----KNAATLIQRHWRGHNCRK 785
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 507 bits (1306), Expect = e-143
Identities = 307/775 (39%), Positives = 440/775 (56%), Gaps = 60/775 (7%)
Query: 335 SNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKL 394
+++ V+D+ L L+E + L Y IY Y G IL+A+NP+Q L +YS +H +
Sbjct: 62 TSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQ 121
Query: 395 YIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKA 454
Y K PPHIFA+AD Y +M + DQC +ISGESGAGKTE+ L++Q L +
Sbjct: 122 YTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS-G 180
Query: 455 NNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKS 514
+ +++++L+ ++EAFGNA TI NDNSSRFGKY+++ F GA+ GA+I +YLLEKS
Sbjct: 181 QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKS 240
Query: 515 RVIHQAIGEKNFHIFYYIYAGLAE--KKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSF 572
RV QA+ E+N+H+FY + G++E KKKL L + YL + T + +++
Sbjct: 241 RVCRQALDERNYHVFYCMLEGMSEDQKKKLG---LGQASDYNYLAMGNCITCEGRVDSQ- 296
Query: 573 YKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTAL 632
+Y I KV+ FT + I +LAAIL++GN+++ + E+ +D + +L
Sbjct: 297 ---EYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFEN-LDACEVLFSPSL 352
Query: 633 ENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVN 692
ASLL + +L LTS ++TRGET+ P + E+A DVRDA K +YGRLF WIV+
Sbjct: 353 ATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVD 412
Query: 693 CINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAW 752
IN+ + S SIG+LDIFGFENF NSFEQLCIN ANE +Q ++ +HVF
Sbjct: 413 KINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKL 472
Query: 753 EQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKF--EG 810
EQ EY E +D IE+ DN LDM KPM ++SL+DEES+FPK TD T++ K +
Sbjct: 473 EQEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQH 532
Query: 811 NLKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQL 870
L + Y E FGI+H+AG V Y GFL KNRDTL DI+ L+ SS N I+Q+
Sbjct: 533 KLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQI 592
Query: 871 VNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYF 930
++A G T ++ T++S F
Sbjct: 593 FQ----------------------------ADVAMG----------AETRKRSPTLSSQF 614
Query: 931 RYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSH 990
+ SL L+ + QP FVRCIKPN ++ +D+ + QLRY+G++ET RIRR G+
Sbjct: 615 KRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPI 674
Query: 991 RILFANFIKRYYLLC--YKSSEEPRMSPDTCATILEK--AGLDNWALGKTKVFLKYYHVE 1046
R F F++RY +L K + + TC + E D+W +GKTK+FLK +H
Sbjct: 675 RYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDM 734
Query: 1047 QLNLMRKEAI-DKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRK 1100
L + R +AI D++IL+Q +R F + K+ K +A +IQ RGH RK
Sbjct: 735 LLEVERDKAITDRVILLQKVIRGFKDRSNFLKL----KNAATLIQRHWRGHNCRK 785
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 491 bits (1263), Expect = e-138
Identities = 294/780 (37%), Positives = 443/780 (56%), Gaps = 39/780 (5%)
Query: 335 SNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKL 394
++++ VDD+ L L+E + L Y + +IY Y G IL+A+NPFQ L LY+ + +L
Sbjct: 62 NSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQL 121
Query: 395 YIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKA 454
Y PPH+FA+A+ Y SM DQC +ISGESGAGKTE L++Q L +
Sbjct: 122 YYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS-G 180
Query: 455 NNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKS 514
+ +++++L+ N ++EAFGNA TI NDNSSRFGKY+++ F SG + GA+I ++LLEKS
Sbjct: 181 QHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKS 240
Query: 515 RVIHQAIGEKNFHIFYYIYAGL-AEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFY 573
RV QA E+N+HIFY + G+ AE K+L P YL + + + + +
Sbjct: 241 RVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEY--HYLTMGNCTSCEGLND---- 294
Query: 574 KSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALE 633
Y I K++ F+ + + +LAAIL++GN+ F + E+ +D S + A
Sbjct: 295 AKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFEN-LDASDVMETPAFP 353
Query: 634 NCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNC 693
LL ++ EL++ L H ++ RGE + R + +A D RDA K +YG LF WIV
Sbjct: 354 TVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKK 413
Query: 694 INSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWE 753
IN+ + + +IG+LDIFGFENF+ NSFEQLCIN ANE +Q ++ QHVF E
Sbjct: 414 INAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTME 473
Query: 754 QNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKFEG-NL 812
Q EY +E++ I Y DN P LD+ KPM ++SLLDEESRFP+ TD T+++K +
Sbjct: 474 QEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHA 533
Query: 813 KSQYFWRPKRM-ELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLV 871
++ F +PK + + FGI H+AG+V Y A GFL KNRD L TDI+ L+ SS N +R++
Sbjct: 534 NNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIF 593
Query: 872 NHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYFR 931
N L +T L H + Q + L A +N + T+ S F+
Sbjct: 594 NLELAET-KLGHGTIR-----QAKAGNHLFKSA-------------DSNKRPSTLGSQFK 634
Query: 932 YSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSHR 991
SL L+ + QP+F+RCIKPN ++ +D+E L QLRY+G++ET IR+ GF R
Sbjct: 635 QSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIR 694
Query: 992 ILFANFIKRYYLL---CYKSSEEPRMSPDTCATILEKAGLD-NWALGKTKVFLKYYHVEQ 1047
F F +R+ +L + + ++ T D +W GKTK+FL+ +
Sbjct: 695 YTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTL 754
Query: 1048 LNLMRKEAIDKLIL-IQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQRKEIV 1106
L + R + +D+ L IQ +R + RY+K +++ +A+ +Q+ RG+ R+ K I+
Sbjct: 755 LEVQRSQVLDRAALSIQKVLRGY----RYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLIL 810
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 476 bits (1225), Expect = e-134
Identities = 287/774 (37%), Positives = 435/774 (56%), Gaps = 57/774 (7%)
Query: 340 VDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
V+D+ LE L E TV L+ + R+ IY Y+G IL+++NP+Q G+Y + + Y G
Sbjct: 1224 VEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRA 1283
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRTL 459
+PPH+FA+A+L + M+ +QCI+ISGESG+GKTE L+++ L + +
Sbjct: 1284 LGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ 1343
Query: 460 QEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQ 519
Q KIL+ L+E+FGNA T+ NDNSSRFGK++E+ F G + GA S+YLLEKSR++ Q
Sbjct: 1344 QIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRIVFQ 1402
Query: 520 AIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQ---NDHLRTVQDIMNNSFYKSQ 576
A E+N+HIFY + AGL + + A + L E + YL N + D
Sbjct: 1403 AKNERNYHIFYELLAGLPAQLRQA-FSLQEAETYYYLNQGGNCEIAGKSD-------ADD 1454
Query: 577 YELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALENCA 636
+ + +V+GF+ E SI+ ILA+IL++GN+ F T+ Q + + + + ++ A
Sbjct: 1455 FRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQ-EVASVVSAREIQAVA 1513
Query: 637 SLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINS 696
LL I + LQ+A+T T E I P TVE A D RDA+AK LY LFSW++ +N+
Sbjct: 1514 ELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNA 1573
Query: 697 LLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNE 756
L+ S D LSI ILDI+GFE+ NSFEQLCIN ANE +QY +N+ VF EQ E
Sbjct: 1574 LV------SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEE 1627
Query: 757 YLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKFEGNLKSQY 816
Y+ E +D + I + DN P +++ KP G+L +LD++ FP+ATD T ++K + +
Sbjct: 1628 YIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANP 1687
Query: 817 FWRPKRMEL-SFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLVNHPL 875
+ +M L F I HYAGKV Y FL KN D + D++ L S V+ L +
Sbjct: 1688 LYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHA 1747
Query: 876 TKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYFRYSLM 935
+ K+ +V T K TVA+ F+ SL+
Sbjct: 1748 PQAAPQRLGKSSSV----------------------------TRLYKAHTVAAKFQQSLL 1779
Query: 936 DLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSHRILFA 995
DL+ KM P F+RC+KPN +++ ++ + V+ QLRY+G+LET RIR+ GF R+ F
Sbjct: 1780 DLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQ 1839
Query: 996 NFIKRYYLLCYKSSEEPRMSPDTCATILE---KAGLDNWALGKTKVFLKYYHVEQLNLMR 1052
FI RY L + P + D C ++L K + + +G +K+FLK + + L MR
Sbjct: 1840 GFIDRYCCLVALKHDLP-ANGDMCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMR 1898
Query: 1053 KEAIDKLIL-IQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQRKEI 1105
+ ++ L +Q C+R F RR++ ++ K I++QS ARG+L R++ +++
Sbjct: 1899 EHVLNLAALTLQRCLRGFFIKRRFRSLRHK----IILLQSRARGYLARQRYQQM 1948
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 471 bits (1211), Expect = e-132
Identities = 319/939 (33%), Positives = 502/939 (53%), Gaps = 87/939 (9%)
Query: 335 SNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSL-GLYSTKHSK 393
+N + VDD+A+L L ++ L + Y R+QIY Y+G IL ++NP+Q + GLY +
Sbjct: 60 TNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATME 119
Query: 394 LYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGK 453
Y PPHIFA+A+ Y+ + + +QCI+ISGESGAGKTE+ L+++ L+V+ +
Sbjct: 120 QYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQ 179
Query: 454 AN-NRTLQEK-------ILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQ 505
+ +L+EK IL+ + ++EAFGNA T+ N+NSSRFGK++++ G + G +
Sbjct: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239
Query: 506 ISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHY-KLPENKPPRYLQNDHL--- 561
I +YLLEK+RV+ Q GE+N+HIFY + AGL +++ Y PEN YL
Sbjct: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENY--HYLNQSGCVED 297
Query: 562 RTVQDIMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQI 621
+T+ D + + + V+ F+ E++ + +LA IL++GNIEF +
Sbjct: 298 KTISD-------QESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAG----- 345
Query: 622 DKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKT 681
+ +S TAL A LL + +L +ALT + RGE I+ P V++A D RD++A
Sbjct: 346 -GAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMA 404
Query: 682 LYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQI 741
LY F W++ INS +K GN D SIGILDIFGFENF+ N FEQ IN ANE++
Sbjct: 405 LYACCFEWVIKKINSRIK------GNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKL 458
Query: 742 QYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATD 801
Q Y+N+H+F+ EQ EY E + I++ DN LD+ ++K +GLL+L++EES FP+ATD
Sbjct: 459 QEYFNKHIFSLEQLEYSREGLVWEDIDWIDNGECLDL-IEKKLGLLALINEESHFPQATD 517
Query: 802 QTLVEKFEGNLKSQYFW-RPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLR 860
TL+EK + +F+ +P+ +FG+ HYAG+V Y+ G L KNRDT D++ LLR
Sbjct: 518 STLLEKLHSQHANNHFYVKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLR 577
Query: 861 SSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTN 920
S I L H R ++ + ++H R
Sbjct: 578 ESRFDFIYDLFEH------------------VSSRNNQDTLKC-------GSKHRR---- 608
Query: 921 MKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILET 980
TV+S F+ SL L++ + P FVRCIKPN ++ ++D+ VL QLRY+G+LET
Sbjct: 609 ---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLET 665
Query: 981 ARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILE--KAGLDNWALGKTKV 1038
RIR+ G++ R F +F KRY +L ++ P C ++L+ A W LGKTKV
Sbjct: 666 VRIRKAGYAVRRPFQDFYKRYKVL-MRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKV 724
Query: 1039 FLKYYHVEQLNLMRKEAID-KLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHL 1097
FL+ ++L R+E + ++I+A V FL ++Y+K+ +IIQ R L
Sbjct: 725 FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKV----LYCVVIIQKNYRAFL 780
Query: 1098 VRKQRKEIVDMKNTAVT---TIQTSDQEFDYKKNFENTRESFVKKQAENAISANERFISA 1154
+R++ + +K A+ ++ Y++ RE KK+ E E+
Sbjct: 781 LRRR---FLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEE----EEKKKRE 833
Query: 1155 PNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYLVGPEVSPK 1214
+ + + + ++E + Q +K + E KQ+ E+
Sbjct: 834 EEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRL 893
Query: 1215 QKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEE-RNCEE 1252
+K ++DL+ +++ EA +Q +R +E R EE
Sbjct: 894 EKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEE 932
>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
Length = 1858
Score = 442 bits (1138), Expect = e-124
Identities = 300/937 (32%), Positives = 502/937 (53%), Gaps = 89/937 (9%)
Query: 341 DDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSKR 400
DDLATL L++ ++ +++K + +QIY ++GDIL+ +NP++ L +YS+ S+LY S
Sbjct: 404 DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSG 463
Query: 401 ---TASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR 457
++ PPH+F+ + + + QC ++SGE G+GK+E + +++ LT A+
Sbjct: 464 KLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRA 523
Query: 458 TLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTS-SGAVVGAQISEYLLEKSRV 516
TL + V ++EAFG+A T +ND SS F KY E++F + GA+I YLLEKSR+
Sbjct: 524 TLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRL 583
Query: 517 IHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENK--PPRYLQNDHLRTVQDIMN---NS 571
+ Q +G+ NF IFY + GL+ ++K Y L N RYL +T+QD + S
Sbjct: 584 VSQPLGQSNFLIFYLLMDGLSAEEK---YGLHLNNLCAHRYLN----QTIQDDASTGERS 636
Query: 572 FYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTA 631
+ + ++++ V+GF+ ++ +++ ILAAIL++G+I F+++ ++ + + +S+
Sbjct: 637 LNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTAL---NEGNSAFVSDLQL 693
Query: 632 LENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIV 691
LE A +L + DEL ALT+ +G+ IIR +T++ A RD +AK+LY RLFS++V
Sbjct: 694 LEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLV 753
Query: 692 NCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFA 751
N +NS L H + L IGILDIFGFE F+KN FEQLC+N+ NE++ +Y N+ +F
Sbjct: 754 NTMNSCL-HSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFL 812
Query: 752 WEQNEYLNEDVDARVIEYEDNW-PLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKFEG 810
EQ E + E V N +LD F QKP G L+LLDEES+ + + +K +
Sbjct: 813 HEQVECVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQS 872
Query: 811 NLKS---QYFWRP----------KRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVL 857
L+S + P K +F I HYAG+V+Y+ G + KN+D+L +++
Sbjct: 873 LLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLF 932
Query: 858 LLRSSDNSVIRQLVNHPLTKTGNL----PHSK---TKNVINYQMRTSEKLINLAKGDTGE 910
++++S+N VI L L++TG+L P K K+ + + T+ +I K
Sbjct: 933 VMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLEL 992
Query: 911 ATRHARETTNMKTQ--------TVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARK 962
+ ++ T+ Q T+AS R SLMD++ K+ PHF+ CI+PN+ +
Sbjct: 993 SKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDT 1052
Query: 963 YDKEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLC--YKSSEEPRMSPDTCA 1020
+D V QL+Y G+LE +I R G+ R+ F++F+ RY L + ++ + + + C
Sbjct: 1053 FDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAAERCR 1112
Query: 1021 TILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQE 1080
+L++ L W +G KVFLKY+H +QLN + + K+I Q +R FL
Sbjct: 1113 LVLQQCKLQGWQMGVRKVFLKYWHADQLNDLCLQLQRKIITCQKVIRGFL---------- 1162
Query: 1081 KRKESAIIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQ 1140
AR HL+ QR I + T++ + + ++ K T ++ V +
Sbjct: 1163 ------------ARQHLL--QRISIRQQEVTSINSFLQNTEDMGLK-----TYDALVIQN 1203
Query: 1141 AENAISANERF---ISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYE 1197
A + N+R ++AP +K + V EE + + + + P M+
Sbjct: 1204 ASDIARENDRLRSEMNAPYHKEKLEVRNMQ----EEGSKRTDDKSGPRHFHPSSMSVCAA 1259
Query: 1198 EEVKQEFYLVGPEV-SPKQKSVKDLEENSNLRKVEKE 1233
+ + LVGP + SP SV ++++S+L K+
Sbjct: 1260 VDGLGQ-CLVGPSIWSPSLHSVFSMDDSSSLPSPRKQ 1295
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 430 bits (1106), Expect = e-120
Identities = 320/1029 (31%), Positives = 515/1029 (50%), Gaps = 83/1029 (8%)
Query: 341 DDLATLEILDENTVSEQLEKCYSRDQ-IYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
+DL L L E V L ++ + IY Y G IL+A+NP++ L +Y Y G
Sbjct: 70 NDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQN 129
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKA-NNRT 458
PHIFA+A+ Y+ M N +Q I++SGESGAGKT +A ++ + K+ +N
Sbjct: 130 MGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH 189
Query: 459 LQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIH 518
+++K+L N + EA GNA T NDNSSRFGKY E+ F ++GA +S YLLEKSRV+
Sbjct: 190 VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVF 249
Query: 519 QAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFYKSQYE 578
Q+ E+N+HIFY + A A++ + H KL + Y + ++ + + + E
Sbjct: 250 QSENERNYHIFYQLCAS-AQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRA------E 302
Query: 579 LIE--QCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALENCA 636
++E + F ++GF + ++ ILAAIL++GN++ ++V E S + + L+
Sbjct: 303 MVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNER---SSVSEDDSHLKVFC 359
Query: 637 SLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINS 696
LL + + + + L + +VT ET+++P T +A + RDA+AK +Y LF +IV IN
Sbjct: 360 ELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQ 419
Query: 697 LLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNE 756
L+ IG+LDI+GFE F NSFEQ CIN ANE++Q +N HVF EQ E
Sbjct: 420 ALQFSGK-----QHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEE 474
Query: 757 YLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKFEGNL--KS 814
Y+ ED+ +I++ DN P++D+ ++ MG+L LLDEE P TD+ ++K N ++
Sbjct: 475 YMKEDIPWTLIDFYDNQPVIDL-IEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRN 533
Query: 815 QYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLVNHP 874
F +P+ SF I H+A KV Y GFL KNRDT+ +V +LR+S +
Sbjct: 534 PLFEKPRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQEN 593
Query: 875 LTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYFRYSL 934
T P S ++I + AK ++H R TV S FR SL
Sbjct: 594 PT-----PPSPFGSMIT---------VKSAKQVIKPNSKHFR-------TTVGSKFRSSL 632
Query: 935 MDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSHRILF 994
L+ + PH+VRCIKPN E+ ++D ++++ QLR G+LET RI + R +
Sbjct: 633 YLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTY 692
Query: 995 ANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGLDN--WALGKTKVFLKYYHVEQLNLMR 1052
F RY +L K + C +L + D+ + GKTK+F + V L +R
Sbjct: 693 IEFYSRYGILMTKQELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLR 752
Query: 1053 KEAI-DKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARG-HLVRKQRKEIVDMKN 1110
+ + +++Q +R +L +++ ++E+R +A+IIQ RG VRK + +
Sbjct: 753 LDKLRQSCVMVQKHMRGWLQRKKF--LRERR--AALIIQQYFRGQQTVRKAITAVALKEA 808
Query: 1111 TAVTTIQTSDQEFDYKKNFENTRESFVKKQA-ENAISANERFISAPNNKGSVSVVKTS-- 1167
A IQ + + + ++ R + + QA A R+ +V + K +
Sbjct: 809 WAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARA 868
Query: 1168 -----TFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYLVGPEVSPKQKSVKDLE 1222
F+ ++ RV + KK+ E++ K+ LV S D+E
Sbjct: 869 WLARRRFQSIRRFVLNIQLTYRVQRLQKKL----EDQNKENHGLVEKLTSLAALRAGDVE 924
Query: 1223 ENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERKAISERPSYPVPWLAENETSFK 1282
K++K EA ++ + T RN EE Y R A+ E+ + +E ET K
Sbjct: 925 ------KIQKLEAELE---KAATHRRNYEEKGKRY--RDAVEEKLAKLQKHNSELETQ-K 972
Query: 1283 KTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAPICSQEEGRGRLRHET--VKERQVEPVT 1340
+ ++ L +++ KEK ++ Q +EE + L ++ +K + E
Sbjct: 973 EQIQLKLQEKT------EELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQI 1026
Query: 1341 QAQEEEDKA 1349
Q+ +EE KA
Sbjct: 1027 QSLKEEIKA 1035
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 426 bits (1096), Expect = e-119
Identities = 338/1167 (28%), Positives = 558/1167 (47%), Gaps = 97/1167 (8%)
Query: 340 VDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
++D+A L L E V L++ Y+ IY Y G + +NP++ L +Y+ + Y G K
Sbjct: 87 IEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKK 146
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLG------- 452
R+ +PPHIF+++D YQ M+T +Q I+I+GESGAGKT N ++Q +
Sbjct: 147 RSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGK 206
Query: 453 ----KANNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISE 508
AN TL+++I+Q N +EAFGNA T+ NDNSSRFGK++ + F ++G + A I
Sbjct: 207 KDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIET 266
Query: 509 YLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIM 568
YLLEKSRVI Q E+N+HIFY I + +K +L L N P D+ Q +
Sbjct: 267 YLLEKSRVIFQLKAERNYHIFYQILSN--KKPELLDMLLVTNNP-----YDYAFVSQGEV 319
Query: 569 NNSFYKSQYELI--EQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHI 626
+ + EL+ + F V+GFT E+ +Y + AI++ GN++F E Q +
Sbjct: 320 SVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGT 379
Query: 627 SNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRL 686
+ + A L+ + + +L + L V E + + +V++ A+AK +Y ++
Sbjct: 380 ED---ADKSAYLMGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKM 436
Query: 687 FSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYN 746
F+W+V IN+ L+ + + IG+LDI GFE F NSFEQLCIN NE++Q ++N
Sbjct: 437 FNWMVTRINATLE-----TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFN 491
Query: 747 QHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVE 806
H+F EQ EY E ++ I++ + ++KPMG++S+L+EE FPKATD T
Sbjct: 492 HHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKA 551
Query: 807 KFEGNL--KSQYFWRPK----RMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLR 860
K N KS F +P+ + E F + HYAG V YN G+L KN+D L +V L +
Sbjct: 552 KLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQ 611
Query: 861 SSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTN 920
S ++ L + T GD+G++ ++ ++
Sbjct: 612 KSSLKLMATLFSSYATAD--------------------------TGDSGKSKGGKKKGSS 645
Query: 921 MKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILET 980
QTV++ R +L L++ + PHFVRCI PN + D V+ QLR G+LE
Sbjct: 646 F--QTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEG 703
Query: 981 ARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCAT--ILEKAGLDN--WALGKT 1036
RI R GF +RIL+ +F +RY +L + E + T +L +D+ + G T
Sbjct: 704 IRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHT 763
Query: 1037 KVFLKYYHVEQLNLMRKEAIDKLIL-IQACVRAFLCSRRYQKIQEKRKESAIIIQSAARG 1095
KVF K + L MR E + ++I +QA R L ++KI E R+++ ++IQ R
Sbjct: 764 KVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFKKIVE-RRDALLVIQWNIRA 822
Query: 1096 HLVRKQ--RKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISANERFIS 1153
+ K ++ + + +T + K+ F +E+ K +A E+ +S
Sbjct: 823 FMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRK-ELEEKMVS 881
Query: 1154 APNNKG----SVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYLVG- 1208
K V + + EE +++ ++ K+MN E+E + L
Sbjct: 882 LLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAK 941
Query: 1209 -----PEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYL--ERK 1261
E S +K + DLE L KVEKE+ ++ + TEE + A L E+K
Sbjct: 942 KRKLEDECSELKKDIDDLE--LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKK 999
Query: 1262 AISERPSYPVPWLAENETSFKKTLEPTLS-QRSIYQNANSMEKEKKTSVVTQRAPICSQE 1320
A+ E + L E + + ++ + S+E+EKK + +RA +
Sbjct: 1000 ALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAK--RKL 1057
Query: 1321 EGRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIV 1380
EG +L E++ + + + + Q +E+ K I + + Q L K +
Sbjct: 1058 EGDLKLTQESIMDLENDKL-QLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQ-- 1114
Query: 1381 TTPTEVARNTHNLYSYPTKHEEINNIKKKDNKDSKATSER--EACGLAIFSKQISKLSE- 1437
+ L + T ++ ++ +++ + SER EA G +++K E
Sbjct: 1115 ---ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA 1171
Query: 1438 EYFILQKKLNEMILSQQLKSLYLGVSH 1464
E+ +++ L E L + + L H
Sbjct: 1172 EFQKMRRDLEEATLQHEATAAALRKKH 1198
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 422 bits (1085), Expect = e-117
Identities = 350/1216 (28%), Positives = 565/1216 (46%), Gaps = 98/1216 (8%)
Query: 293 KDVMLQKQLTEFIG--IHQCMGGTEKARRE---RIHTKKGNFNRPLISNLKDVDDLATLE 347
KDV + EF+ I GG A E + K+ + ++D+A L
Sbjct: 35 KDVFVPDDKQEFVKAKIVSREGGKVTAETEYGKTVTVKEDQVMQQNPPKFDKIEDMAMLT 94
Query: 348 ILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSKRTASPPHI 407
L E V L+ Y IY Y G + +NP++ L +Y+ + Y G KR+ +PPHI
Sbjct: 95 FLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHI 154
Query: 408 FAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR---------- 457
F+++D YQ M+T +Q I+I+GESGAGKT N ++Q V+ +R
Sbjct: 155 FSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKG 214
Query: 458 TLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVI 517
TL+++I+Q N +EAFGNA T+ NDNSSRFGK++ + F ++G + A I YLLEKSRVI
Sbjct: 215 TLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVI 274
Query: 518 HQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFYKSQY 577
Q E+++HIFY I + +K +L L N P Y T ++++ +
Sbjct: 275 FQLKAERDYHIFYQILSN--KKPELLDMLLITNNPYDYAFISQGETTVASIDDA---EEL 329
Query: 578 ELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALENCAS 637
+ F V+GFT E+ S+Y + AI++ GN++F E Q + + A
Sbjct: 330 MATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEE---ADKSAY 386
Query: 638 LLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINSL 697
L+ + + +L + L V E + + V++ A+AK +Y R+F+W+V IN+
Sbjct: 387 LMGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINAT 446
Query: 698 LKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNEY 757
L+ + + IG+LDI GFE F NSFEQLCIN NE++Q ++N H+F EQ EY
Sbjct: 447 LE-----TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEY 501
Query: 758 LNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEK-FEGNL-KSQ 815
E ++ I++ + ++KPMG++S+L+EE FPKATD T K F+ +L KS
Sbjct: 502 KKEGIEWTFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSA 561
Query: 816 YFWRPKRM----ELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLV 871
F +P+ + E F + HYAG V YN G+L KN+D L +V L + S ++ L
Sbjct: 562 NFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTL- 620
Query: 872 NHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYFR 931
N A D + QTV++ R
Sbjct: 621 ----------------------------FANYAGADAPIEKGKGKAKKGSSFQTVSALHR 652
Query: 932 YSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSHR 991
+L L++ + PHFVRCI PN + D V+ QLR G+LE RI R GF +R
Sbjct: 653 ENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNR 712
Query: 992 ILFANFIKRYYLLCYKSSEEPRM--SPDTCATILEKAGLDN--WALGKTKVFLKYYHVEQ 1047
IL+ +F +RY +L + E + S +L +D+ + G TKVF K +
Sbjct: 713 ILYGDFRQRYRILNPAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGL 772
Query: 1048 LNLMRKEAIDKLIL-IQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQ--RKE 1104
L MR E + ++I IQA R L Y+K+ E R++S ++IQ R + K +
Sbjct: 773 LEEMRDERLSRIITRIQAQSRGVLARMEYKKLLE-RRDSLLVIQWNIRAFMGVKNWPWMK 831
Query: 1105 IVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISANERFISAPNNKG----S 1160
+ + + + + K+ F +E+ K +A E+ +S K
Sbjct: 832 LYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRK-ELEEKMVSLLQEKNDLQLQ 890
Query: 1161 VSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYLVG------PEVSPK 1214
V + + EE +++ ++ K+MN E+E + L E S
Sbjct: 891 VQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 950
Query: 1215 QKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYL--ERKAISERPSYPVP 1272
++ + DLE L KVEKE+ ++ + TEE + A L E+KA+ E +
Sbjct: 951 KRDIDDLE--LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALD 1008
Query: 1273 WL-AENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAPICSQEEGRGRLRHETV 1331
L AE + T ++ + S+E+EKK + +RA + EG +L E++
Sbjct: 1009 DLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAK--RKLEGDLKLTQESI 1066
Query: 1332 KERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIVTTPTEVARNTH 1391
+ +E Q +E K F + +Q + S +++ +
Sbjct: 1067 MD--LENDKQQLDERLKKKDFELNALNARIEDEQ----ALGSQLQKKLKELQARIEELEE 1120
Query: 1392 NLYSYPTKHEEINNIKKKDNKDSKATSER--EACGLAIFSKQISKLSE-EYFILQKKLNE 1448
L + T ++ ++ +++ + SER EA G +++K E E+ +++ L E
Sbjct: 1121 ELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1180
Query: 1449 MILSQQLKSLYLGVSH 1464
L + + L H
Sbjct: 1181 ATLQHEATAAALRKKH 1196
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 417 bits (1072), Expect = e-116
Identities = 350/1188 (29%), Positives = 561/1188 (47%), Gaps = 141/1188 (11%)
Query: 340 VDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
++D+A L L+E V L+ Y+ IY Y G + +NP++ L +Y+ + + Y G K
Sbjct: 88 IEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKK 147
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR-- 457
R +PPHIF+++D YQ M+T +Q I+I+GESGAGKT N ++Q + +
Sbjct: 148 RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAK 207
Query: 458 --------TLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEY 509
TL+++I+ N L+EAFGNA T+ NDNSSRFGK++ + F ++G + A I Y
Sbjct: 208 KKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETY 267
Query: 510 LLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMN 569
LLEKSRV Q E+++HIFY I + +K +L L P Y + +I+
Sbjct: 268 LLEKSRVTFQLKAERSYHIFYQILSN--KKPELIELLLITTNPYDY----PFISQGEILV 321
Query: 570 NSFYKSQYELI-EQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQI--DKSHI 626
S ++ L + ++GFT E+ +Y + A+++ GN++F E Q D + +
Sbjct: 322 ASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEV 381
Query: 627 SNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRL 686
++ TA L+ + + +L +AL V E + + TV++ +A++K++Y +L
Sbjct: 382 ADKTAY-----LMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKL 436
Query: 687 FSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYN 746
F W+V IN L + IG+LDI GFE F+ NS EQLCIN NE++Q ++N
Sbjct: 437 FLWMVTRINQQLDTKLPR-----QHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFN 491
Query: 747 QHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVE 806
H+F EQ EY E ++ I++ + ++KPMG+ S+L+EE FPKATD +
Sbjct: 492 HHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKN 551
Query: 807 K-FEGNL-KSQYFWRPK----RMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLR 860
K ++ +L KS F +PK R E F + HYAG V Y+ SG+L KN+D L +V L +
Sbjct: 552 KLYDQHLGKSNNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQ 611
Query: 861 SSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTN 920
S N ++ L A D + +
Sbjct: 612 KSSNRLLAHL-----------------------------YATFATADADSGKKKVAKKKG 642
Query: 921 MKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILET 980
QTV++ FR +L L+S + PHFVRCI PN + + VL QLR G+LE
Sbjct: 643 SSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEG 702
Query: 981 ARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRM--SPDTCATILEKAGLDN--WALGKT 1036
RI R GF +RIL+ +F +RY +L + E + S C +L +D+ + G T
Sbjct: 703 IRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSKKACEKLLASIDIDHTQYKFGHT 762
Query: 1037 KVFLKYYHVEQLNLMRKEAIDKLIL-IQACVRAFLCSRRYQKIQEKRKESAIIIQSAARG 1095
KVF K + L MR + + KLI QA R FL +QK+ + R+ES IQ R
Sbjct: 763 KVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQ-RRESIFCIQYNIRS 821
Query: 1096 HLVRKQ---RKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISANERFI 1152
+ K K +K + + +T + K+ F+ T++ K +A+ E+ +
Sbjct: 822 FMNVKHWPWMKLFFKIK-PLLKSAETEKEMATMKEEFQKTKDELAKSEAKRK-ELEEKLV 879
Query: 1153 SAPNNKGSVSVVKTSTFKPEEETTNAVESNNRV-------YQTPKKMNNVY-----EEEV 1200
+ K + + + + E+ N +++ R +Q K+ V EEE+
Sbjct: 880 TLVQEKNDLQL------QVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEI 933
Query: 1201 KQEFYL----VGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAA 1256
E + E S +K + DLE L KVEKE+ ++ + TEE + + A
Sbjct: 934 NAELTAKKRKLEDECSELKKDIDDLE--LTLAKVEKEKHATENKVKNLTEELSGLDETIA 991
Query: 1257 YL--ERKAISERPSYPVPWLAENETSFKKTLEPTLS--QRSIYQNANSMEKEKKTSVVTQ 1312
L E+KA+ E + L E +L T S ++ + +S+E+EKK V +
Sbjct: 992 KLTREKKALQEAHQQALDDLQAEEDKV-NSLNKTKSKLEQQVEDLESSLEQEKKLRVDLE 1050
Query: 1313 R-------------APICSQEEGRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQSKYRG 1359
R I E + +L E +K++ E + ED+ + +Q + +
Sbjct: 1051 RNKRKLEGDLKLAQESILDLENDKQQL-DERLKKKDFEYCQLQSKVEDEQTLGLQFQ-KK 1108
Query: 1360 YKRRQQLRKDKMSSFKHQRIVTTPTEVARNTHNLYSYPTKHEEINNIKKKDNKDSKATSE 1419
K Q ++ + +R TE R+ Y + EE+ SE
Sbjct: 1109 IKELQARIEELEEEIEAERATRAKTEKQRS-----DYARELEEL--------------SE 1149
Query: 1420 R--EACGLAIFSKQISKLSE-EYFILQKKLNEMILSQQLKSLYLGVSH 1464
R EA G+ +++K E E+ L++ L E L + L H
Sbjct: 1150 RLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKH 1197
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 416 bits (1070), Expect = e-116
Identities = 329/1155 (28%), Positives = 556/1155 (48%), Gaps = 104/1155 (9%)
Query: 341 DDLATLEILDENTVSEQLE-KCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
+DL L L E V L+ + + IY Y G +L+A+NP++ L +Y Y G
Sbjct: 72 NDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQN 131
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQL-TVLGKANNRT 458
PHIFA+A+ Y+ M +Q I++SGESGAGKT +A ++ TV G A+
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETN 191
Query: 459 LQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIH 518
++EK+L + ++EA GNA T NDNSSRFGKY+++ F ++GA + YLLEKSRV+
Sbjct: 192 IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVF 251
Query: 519 QAIGEKNFHIFYYI--YAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFYKSQ 576
QA E+N+HIFY + AGL E K+LA L + Y +++ + +
Sbjct: 252 QADDERNYHIFYQLCAAAGLPEFKELA---LTSAEDFFYTSQGGDTSIEGVDD----AED 304
Query: 577 YELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHIS-NHTALENC 635
+E Q F ++G SI+ I+A+IL++G++ ++ E D IS L N
Sbjct: 305 FEKTRQAFTLLGVKESHQMSIFKIIASILHLGSV---AIQAERDGDSCSISPQDVYLSNF 361
Query: 636 ASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCIN 695
LL + +++ L +VT ET ++ ++++ + R+A+AK +Y +LF WIV IN
Sbjct: 362 CRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHIN 421
Query: 696 SLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQN 755
L H S + IG+LDI+GFE F+ NSFEQ CIN ANE++Q +N HVF EQ
Sbjct: 422 KAL-HTSLKQHS----FIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQE 476
Query: 756 EYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEK-FEGNLKS 814
EY+ E + +I++ DN P +D+ ++ +G+L LLDEE + PK TDQ +K ++ + S
Sbjct: 477 EYMKEQIPWTLIDFYDNQPCIDL-IEAKLGILDLLDEECKVPKGTDQNWAQKLYDRHSSS 535
Query: 815 QYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLVNH- 873
Q+F +P+ +F I H+A KV Y + GFL KNRDT+ + + +L++S ++ L +
Sbjct: 536 QHFQKPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDD 595
Query: 874 ----PLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASY 929
P T G SK +R++ + ++ + +TV
Sbjct: 596 KDPVPATTPGKGSSSK------ISVRSARPPMKVSNKE--------------HKKTVGHQ 635
Query: 930 FRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFS 989
FR SL L+ + PH+VRCIKPN E+ +D ++ + QLR G+LET RI G+
Sbjct: 636 FRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYP 695
Query: 990 HRILFANFIKRYYLLCYKSSEEPRMSPDTCATILEK--AGLDNWALGKTKVFLKYYHVEQ 1047
R + +F RY +L K C ++LE D + G+TK+F + V
Sbjct: 696 SRWAYHDFFNRYRVLVKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAY 755
Query: 1048 LNLMRKEAI-DKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQRKEIV 1106
L +R + I+IQ VR +L +Y ++ K + + +Q RGHL R+ + +
Sbjct: 756 LEKLRADKFRTATIMIQKTVRGWLQKVKYHRL----KGATLTLQRYCRGHLARRLAEHLR 811
Query: 1107 DMKNTAVT----TIQTSDQEFDYKKNF-----ENTRESFVKKQAENAISANERFISAPNN 1157
++ V +Q + Q + + TR FV++ + ++ +
Sbjct: 812 RIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHV 871
Query: 1158 KGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYL---VGPEVSPK 1214
+G ++ F+ + ++ R+ + +++ + E E VG E
Sbjct: 872 RGWMA---RRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVV 928
Query: 1215 QKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERKAISERPSYPVPWL 1274
Q K E+N + + ++ ++ S Y E E + S R L
Sbjct: 929 QLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLR-------L 981
Query: 1275 AENETSFKKTLEPTLSQRSIYQNANSMEKE---KKTSVVTQRAPICSQE----------E 1321
E S + L+ S+R I ++A+S EK+ K+ + + Q + E +
Sbjct: 982 QEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQ 1041
Query: 1322 GRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFK----HQ 1377
+ +VKE ++ + EEE + +Y ++R +D+M+ K H+
Sbjct: 1042 SKDEFAQNSVKENLMK---KELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHR 1098
Query: 1378 RIVTTPTEVARNTHNLYSYPT-KHEEINNIKKKDNKDSKATSEREACGLAIF---SKQIS 1433
R + + + ++ +YP+ EI + + + + E+ A + +F K++
Sbjct: 1099 RNPSNQSSLESDS----NYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVR 1154
Query: 1434 KLSEEYFILQKKLNE 1448
+L +E LQ +L +
Sbjct: 1155 ELEQERKKLQVQLEK 1169
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 415 bits (1067), Expect = e-115
Identities = 336/1162 (28%), Positives = 550/1162 (47%), Gaps = 90/1162 (7%)
Query: 341 DDLATLEILDENTVSEQLEKCYSRDQ-IYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
+DL L L E V L + + IY Y G +L+A+NP++ L +Y Y G
Sbjct: 72 NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQN 131
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQL-TVLGKANNRT 458
PHIFA+A+ Y+ M +Q I++SGESGAGKT +A ++ TV G A+
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191
Query: 459 LQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIH 518
++EK+L N ++E+ GNA T NDNSSRFGKY+E+ F ++GA + YLLEKSRV+
Sbjct: 192 VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVF 251
Query: 519 QAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQD----IMNNSFYK 574
QA E+N+HIFY + A KLPE K R D+ + ++
Sbjct: 252 QAEEERNYHIFYQLCASA---------KLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDA 302
Query: 575 SQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHI-SNHTALE 633
+ Q ++G + I+ ILA IL++GN+ F T D I H L
Sbjct: 303 KEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF----TSRDADSCTIPPKHEPLC 358
Query: 634 NCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNC 693
L+ + +E+ L + T ET I+P + +AT+ RDA+AK +Y +LF+WIV+
Sbjct: 359 IFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDN 418
Query: 694 INSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWE 753
+N L S IG+LDI+GFE F+ NSFEQ CIN ANE++Q +N HVF E
Sbjct: 419 VNQALH-----SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLE 473
Query: 754 QNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKFEGN-- 811
Q EY+ E + +I++ DN P +++ ++ +G+L LLDEE + PK TD T +K
Sbjct: 474 QEEYMKEQIPWTLIDFYDNQPCINL-IESKLGILDLLDEECKMPKGTDDTWAQKLYNTHL 532
Query: 812 LKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLV 871
K F +P+ +F I H+A KV Y GFL KN+DT+ + + +L+SS ++ +L
Sbjct: 533 NKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELF 592
Query: 872 NHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYFR 931
+ P S T + RT K KG G+ + + +TV FR
Sbjct: 593 QD--DEKAISPTSATSSGRTPLTRTPAK---PTKGRPGQMAKEHK-------KTVGHQFR 640
Query: 932 YSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSHR 991
SL L+ + PH+VRCIKPN + +D+++ + QLR G+LET RI GF R
Sbjct: 641 NSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSR 700
Query: 992 ILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGL--DNWALGKTKVFLKYYHVEQLN 1049
+ F RY +L K + TC +LEK L D + GKTK+F + V L
Sbjct: 701 WTYQEFFSRYRVL-MKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLE 759
Query: 1050 LMRKEAI-DKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQRKEIVDM 1108
+R + + I IQ +R +L ++Y ++ +++AI +Q RG+ R K +
Sbjct: 760 KLRADKLRAACIRIQKTIRGWLLRKKYLRM----RKAAITMQRYVRGYQARCYAKFL--R 813
Query: 1109 KNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAE-NAISANERFISAPNNKGSVSVVK-- 1165
+ A T IQ + + ++ ++ R + + Q+ A R+ +V + K
Sbjct: 814 RTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRV 873
Query: 1166 -----TSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYL---VGPEVSPKQKS 1217
+ +K ++ R +++ + E E Y +G E Q
Sbjct: 874 RGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQ 933
Query: 1218 VKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERKAISERPSY----PVPW 1273
K E+N + + + ++ ++ Y TE+ + LER +SE + V
Sbjct: 934 RKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSD------LERLQLSEEEAKVATGRVLS 987
Query: 1274 LAENETSFKKTLEPTLSQRS-IYQNANSMEKEKKTSVVTQRAPICSQEEGRGRLRH---- 1328
L E +K LE T S++ I ++A+ ++E + V + ++ + L H
Sbjct: 988 LQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQ 1047
Query: 1329 ------ETVKERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIVTT 1382
ET++++ VE Q + + + + Q+ + R ++ D V
Sbjct: 1048 QAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPK 1107
Query: 1383 P-TEVARNTHNL----YSYPTKHEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSE 1437
P + +TH+ Y + ++ E+ +I + + S+ + K++++L +
Sbjct: 1108 PGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQ 1167
Query: 1438 EYFILQKKLN---EMILSQQLK 1456
E ++Q +L+ E +L + K
Sbjct: 1168 EKQVMQDELDRKEEQVLRSKAK 1189
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 415 bits (1067), Expect = e-115
Identities = 336/1162 (28%), Positives = 550/1162 (47%), Gaps = 90/1162 (7%)
Query: 341 DDLATLEILDENTVSEQLEKCYSRDQ-IYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
+DL L L E V L + + IY Y G +L+A+NP++ L +Y Y G
Sbjct: 72 NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQN 131
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQL-TVLGKANNRT 458
PHIFA+A+ Y+ M +Q I++SGESGAGKT +A ++ TV G A+
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191
Query: 459 LQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIH 518
++EK+L N ++E+ GNA T NDNSSRFGKY+E+ F ++GA + YLLEKSRV+
Sbjct: 192 VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVF 251
Query: 519 QAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQD----IMNNSFYK 574
QA E+N+HIFY + A KLPE K R D+ + ++
Sbjct: 252 QAEEERNYHIFYQLCASA---------KLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDA 302
Query: 575 SQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHI-SNHTALE 633
+ Q ++G + I+ ILA IL++GN+ F T D I H L
Sbjct: 303 KEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF----TSRDADSCTIPPKHEPLC 358
Query: 634 NCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNC 693
L+ + +E+ L + T ET I+P + +AT+ RDA+AK +Y +LF+WIV+
Sbjct: 359 IFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDN 418
Query: 694 INSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWE 753
+N L S IG+LDI+GFE F+ NSFEQ CIN ANE++Q +N HVF E
Sbjct: 419 VNQALH-----SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLE 473
Query: 754 QNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKFEGN-- 811
Q EY+ E + +I++ DN P +++ ++ +G+L LLDEE + PK TD T +K
Sbjct: 474 QEEYMKEQIPWTLIDFYDNQPCINL-IESKLGILDLLDEECKMPKGTDDTWAQKLYNTHL 532
Query: 812 LKSQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLV 871
K F +P+ +F I H+A KV Y GFL KN+DT+ + + +L+SS ++ +L
Sbjct: 533 NKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELF 592
Query: 872 NHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMKTQTVASYFR 931
+ P S T + RT K KG G+ + + +TV FR
Sbjct: 593 QD--DEKAISPTSATSSGRTPLTRTPAK---PTKGRPGQMAKEHK-------KTVGHQFR 640
Query: 932 YSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARIRRLGFSHR 991
SL L+ + PH+VRCIKPN + +D+++ + QLR G+LET RI GF R
Sbjct: 641 NSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSR 700
Query: 992 ILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGL--DNWALGKTKVFLKYYHVEQLN 1049
+ F RY +L K + TC +LEK L D + GKTK+F + V L
Sbjct: 701 WTYQEFFSRYRVL-MKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLE 759
Query: 1050 LMRKEAI-DKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQRKEIVDM 1108
+R + + I IQ +R +L ++Y ++ +++AI +Q RG+ R K +
Sbjct: 760 KLRADKLRAACIRIQKTIRGWLLRKKYLRM----RKAAITMQRYVRGYQARCYAKFL--R 813
Query: 1109 KNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAE-NAISANERFISAPNNKGSVSVVK-- 1165
+ A T IQ + + ++ ++ R + + Q+ A R+ +V + K
Sbjct: 814 RTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRV 873
Query: 1166 -----TSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYL---VGPEVSPKQKS 1217
+ +K ++ R +++ + E E Y +G E Q
Sbjct: 874 RGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQ 933
Query: 1218 VKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERKAISERPSY----PVPW 1273
K E+N + + + ++ ++ Y TE+ + LER +SE + V
Sbjct: 934 RKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSD------LERLQLSEEEAKVATGRVLS 987
Query: 1274 LAENETSFKKTLEPTLSQRS-IYQNANSMEKEKKTSVVTQRAPICSQEEGRGRLRH---- 1328
L E +K LE T S++ I ++A+ ++E + V + ++ + L H
Sbjct: 988 LQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQ 1047
Query: 1329 ------ETVKERQVEPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIVTT 1382
ET++++ VE Q + + + + Q+ + R ++ D V
Sbjct: 1048 QAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPK 1107
Query: 1383 P-TEVARNTHNL----YSYPTKHEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSE 1437
P + +TH+ Y + ++ E+ +I + + S+ + K++++L +
Sbjct: 1108 PGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQ 1167
Query: 1438 EYFILQKKLN---EMILSQQLK 1456
E ++Q +L+ E +L + K
Sbjct: 1168 EKQVMQDELDRKEEQVLRSKAK 1189
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 412 bits (1060), Expect = e-114
Identities = 342/1175 (29%), Positives = 556/1175 (47%), Gaps = 111/1175 (9%)
Query: 320 ERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALN 379
+++ K + + V+D+A L L+E +V L++ Y IY Y G + +N
Sbjct: 63 KKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVIN 122
Query: 380 PFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTE 439
P+++L +YS + ++Y G KR PPHI+A+ D Y+SM+ DQ I+ +GESGAGKTE
Sbjct: 123 PYKNLPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTE 182
Query: 440 NAHLLVQQLTVLG-----KANNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMK 494
N ++Q L + K + L+ ++LQ N ++EAFGNA T+ NDNSSRFGK++ +
Sbjct: 183 NTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRIN 242
Query: 495 FTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPR 554
F +G +VGA I YLLEKSR I QA E+ FHIFYY+ +G E K P NK R
Sbjct: 243 FDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNK-YR 301
Query: 555 YLQNDHLRTVQDIMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSS 614
+L N H+ T+ + ++ E +++G E+ + +++ +L +GNI F
Sbjct: 302 FLSNGHV-TIPGQQDKDMFQETME----AMRIMGIPEEEQMGLLRVISGVLQLGNIVFKK 356
Query: 615 VATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDV 674
E D++ + ++TA + + LL I + + + + + + + T E+A
Sbjct: 357 ---ERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFA 413
Query: 675 RDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCI 734
+A+AK Y R+F W+V IN L + IGILDI GFE F NSFEQLCI
Sbjct: 414 IEALAKATYERMFRWLVLRINKALDKTKRQGAS----FIGILDIAGFEIFDLNSFEQLCI 469
Query: 735 NIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYE-DNWPLLDMFLQK--PMGLLSLLD 791
N NE++Q +N +F EQ EY E ++ I++ D P +D+ + P G+L+LLD
Sbjct: 470 NYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLD 529
Query: 792 EESRFPKATDQTLVEK-FEGNLKSQYFWRPKRM--ELSFGIHHYAGKVLYNASGFLAKNR 848
EE FPKATD++ VEK + F +PK++ + F I HYAGKV Y A +L KN
Sbjct: 530 EECWFPKATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNM 589
Query: 849 DTLPTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINL--AKG 906
D L +I LL S + + +L + +++I L G
Sbjct: 590 DPLNDNIATLLHQSSDKFVSEL-----------------------WKDVDRIIGLDQVAG 626
Query: 907 DTGEATRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKE 966
+ A A +T +TV ++ L L++ + P+FVRCI PN E++A K D
Sbjct: 627 MSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPH 686
Query: 967 KVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRM-SPDTCATILEK 1025
VL QLR G+LE RI R GF +R++F F +RY +L S + M C +++
Sbjct: 687 LVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKA 746
Query: 1026 AGLDN--WALGKTKVFLKYYHVEQLNLMRKEAI-DKLILIQACVRAFLCSRRYQKIQEKR 1082
LD+ + +G++KVF + + L R I D +I QAC R +L + + K Q++
Sbjct: 747 LELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQL 806
Query: 1083 KESAIIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAE 1142
++ ++ A +R + + K + + ++E +E + K E
Sbjct: 807 TAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEM-------MAKEEELVKVRE 859
Query: 1143 NAISANERFISAPNNKGSVSVVKTSTFKP-EEETTNAVESNN-RVYQTPKKMN------- 1193
++A R + + K + + ET E+ R T KK
Sbjct: 860 KQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHD 919
Query: 1194 -NVYEEEVKQEFYLVGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEE 1252
EE ++ + E Q+++++LEE ++E+EE S Q+ E+ E
Sbjct: 920 LEARVEEEEERCQHLQAEKKKMQQNIQELEE-----QLEEEE----SARQKLQLEKVTTE 970
Query: 1253 SKAAYLERKAISERPSYPVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQ 1312
+K LE + I + E++ + L R N E+E+K+ + +
Sbjct: 971 AKLKKLEEEQI----------ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAK 1020
Query: 1313 -----RAPICSQEEGRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQ-SKYRGYKRRQQL 1366
A I EE RLR E K+RQ T+ + E D + Q ++ + ++
Sbjct: 1021 LKNKHEAMITDLEE---RLRREE-KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKM 1076
Query: 1367 RKDKMSSFKHQRIVTTPTEVARNTHNLYSYPTKHEEINNIKKKDNKDSKATSEREACGLA 1426
+ K + E A+ L +I+ + +++ +S+ S +A
Sbjct: 1077 QLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISEL--QEDLESERASRNKA---- 1130
Query: 1427 IFSKQISKLSEEYFILQKKLNEMILS----QQLKS 1457
KQ L EE L+ +L + + S Q+L+S
Sbjct: 1131 --EKQKRDLGEELEALKTELEDTLDSTAAQQELRS 1163
Score = 38.1 bits (87), Expect = 0.070
Identities = 77/417 (18%), Positives = 169/417 (40%), Gaps = 64/417 (15%)
Query: 1060 ILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHL-VRKQRKEIVDMKNTAVTTIQT 1118
+L Q+ ++ ++ + ++ + +++ ++Q R L + + K++ D KN+ ++
Sbjct: 1288 LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE- 1346
Query: 1119 SDQEFDYKKNFE------NTRESFVKKQAENAISANERFISAPNNKGSVSVVKTSTFKPE 1172
+E + K N E + + + +KK+ E+++ E + VK K
Sbjct: 1347 --EEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLE----------TAEEVKRKLQKDL 1394
Query: 1173 EETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYLVGPEVSPKQKSVKDLEENSNLRKVEK 1232
E + E Y +K ++E+ ++ +++S +LE+ +K ++
Sbjct: 1395 EGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLV----DLDHQRQSACNLEKKQ--KKFDQ 1448
Query: 1233 EEAMIQSYYQRYTEERNCEESKAAYLERKAISERPSYPVPWLAENETSFKKTLEPTLSQR 1292
A ++ +Y EER+ E++A E KA+ S + LE + Q+
Sbjct: 1449 LLAEEKTISAKYAEERDRAEAEAREKETKAL----------------SLARALEEAMEQK 1492
Query: 1293 SIYQNANSMEKEKKTSVVTQRAPICSQEEGRGRLRHETVK-----ERQVEPV-TQAQEEE 1346
+ + N + T+ + S ++ G+ HE K E+QVE + TQ +E E
Sbjct: 1493 AELERLNKQFR-------TEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 1545
Query: 1347 DKAAVFIQSKYRGYKRRQQLR---------KDKMSSFKHQRIVTTPTEVARNTHNLYSYP 1397
D+ +K R Q ++ +D+ S K +++V E+ +
Sbjct: 1546 DELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQR 1605
Query: 1398 TKHEEINNIKKKDNKDSKATSEREACGLAIFSKQISKLSEEYFILQKKLNEMILSQQ 1454
+ + D KD +A + KQ+ KL + ++L++ S++
Sbjct: 1606 SMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASRE 1662
Score = 35.0 bits (79), Expect = 0.59
Identities = 58/324 (17%), Positives = 121/324 (37%), Gaps = 35/324 (10%)
Query: 1044 HVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQRK 1103
H++ N R EAI +L +QA ++ C R + R+E I+ Q+ ++
Sbjct: 1625 HIDSANKNRDEAIKQLRKLQAQMKD--CMRELDDTRASREE--ILAQAKENEKKLKSMEA 1680
Query: 1104 EIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISANERFISAPNNKGSVSV 1163
E++ ++ E K+QA+ I+ + KG++++
Sbjct: 1681 EMIQLQE-------------------ELAAAERAKRQAQQERDELADEIANSSGKGALAL 1721
Query: 1164 VKTSTFKPE----EETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYLVGPEVSPKQKSVK 1219
+ + EE + N + K N+ +++ + L + + +
Sbjct: 1722 EEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQ 1781
Query: 1220 DLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERKAISERPSYPVPWLAENET 1279
LE + KV+ +E M + +Y E+K A LE + +E T
Sbjct: 1782 QLERQNKELKVKLQE-MEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRT 1840
Query: 1280 SFKKTLEPTLSQ-----RSIYQNANSMEKEKKTSVVTQRAPICSQEEGRGRLRHETVKER 1334
+K L+ L Q R+ Q + +K +R ++EE + +R
Sbjct: 1841 --EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQR 1898
Query: 1335 QVEPVTQAQEEEDKAAVFIQSKYR 1358
++E T+ + ++ +++K R
Sbjct: 1899 ELEDATETADAMNREVSSLKNKLR 1922
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 412 bits (1058), Expect = e-114
Identities = 228/549 (41%), Positives = 338/549 (61%), Gaps = 17/549 (3%)
Query: 338 KDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIG 397
KD DDL +L L+E T+ E L + ++IY YVG ILI +NPF+ L +Y+ K+ K+Y
Sbjct: 146 KDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIVINPFKFLPIYNPKYVKMYDN 205
Query: 398 SKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR 457
+ PHI+A+AD+ Y +M+ +QCIVISGESG+GKT++ + L+ LT L +
Sbjct: 206 HQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIHHLTALSQKGFA 265
Query: 458 T-LQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRV 516
+ +++ IL ++EAFGNA T N+NSSRFGK++++ + +G V+GA + +YLLEKSR+
Sbjct: 266 SGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNYQETGTVLGAYVEKYLLEKSRL 325
Query: 517 IHQAIGEKNFHIFYYIYAGLAEKKKLA-HYKLPEN---------KPPRYLQNDHLRTVQD 566
++Q E+N+H+FYY+ AG +E ++ A H K PE KP R +D+ +
Sbjct: 326 VYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYLNQITKKPLRQSWDDYCYDSEP 385
Query: 567 ---IMNNSFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDK 623
+ + +E ++ +++GF + I+S+L+AIL++GNI + ++ D
Sbjct: 386 DCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNICYKKKT--YRDDS 443
Query: 624 SHISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLY 683
I N L + LL ++ + L EAL + VT GE +I P + +A VR++MAK+LY
Sbjct: 444 IDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMAKSLY 503
Query: 684 GRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQY 743
LF WIV IN L + N LSIG+LDIFGFE+++ NSFEQ CIN ANE++Q+
Sbjct: 504 SALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQH 563
Query: 744 YYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQT 803
Y+NQH+F EQ EY E + I+Y DN +++ +KP GLL LLDEES FP+AT+QT
Sbjct: 564 YFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQT 623
Query: 804 LVEKFEGNLK-SQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSS 862
L++KF+ + + Y P ME +F I HYAGKV Y F KN D + DIV LLRSS
Sbjct: 624 LLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSS 683
Query: 863 DNSVIRQLV 871
N+ I ++
Sbjct: 684 KNAFISGMI 692
Score = 102 bits (255), Expect = 2e-21
Identities = 62/215 (28%), Positives = 118/215 (54%), Gaps = 10/215 (4%)
Query: 922 KTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETA 981
K ++++ F+ SL L+ + +P+FV+CI+ N+E+ ++ VL QLRYTG+LET
Sbjct: 886 KPPSISAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETV 945
Query: 982 RIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGL--DNWALGKTKVF 1039
RIR+ G+S + F +F+ +++L ++ + + K L DN+ +GKT VF
Sbjct: 946 RIRQSGYSSKYSFQDFVSHFHVLLPRNIIPSKFN---IQDFFRKINLNPDNYQVGKTMVF 1002
Query: 1040 LKYYHVEQL-NLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLV 1098
LK + L +L+ +E + ++IL+Q R LC + + + +++++IIQ R +L
Sbjct: 1003 LKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHL----RQASVIIQRFWRNYLN 1058
Query: 1099 RKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTR 1133
+KQ ++ K+ V + + ++ + E R
Sbjct: 1059 QKQVRDAAVQKDAFVMASAAALLQASWRAHLERQR 1093
Score = 33.5 bits (75), Expect = 1.7
Identities = 38/159 (23%), Positives = 76/159 (47%), Gaps = 29/159 (18%)
Query: 1060 ILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVRKQRKE--------------I 1105
I IQA +A+ S+RYQ E+RK+ I++QS RG R++ K +
Sbjct: 1120 ICIQARWKAYRESKRYQ---EQRKK-IILLQSTCRGFRARQRFKALKEQRLRETKPEVGL 1175
Query: 1106 VDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISANERFISAPNNKGSVSVVK 1165
V++K IQ SD +F+N ++ ++ ++ I +N + + SV +K
Sbjct: 1176 VNIKGYGSLEIQGSDPSGWEDCSFDNRIKAI--EECKSVIESNR-----ISRESSVDCLK 1228
Query: 1166 TSTFKPEEETTNA----VESNNRVYQTPKKMNNVYEEEV 1200
S K +E + ++ + V + P+ + ++++++V
Sbjct: 1229 ESPNKQQERAQSQSGVDLQEDVLVRERPRSLEDLHQKKV 1267
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 411 bits (1056), Expect = e-114
Identities = 326/1058 (30%), Positives = 506/1058 (47%), Gaps = 95/1058 (8%)
Query: 340 VDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
++D+A + L E V L++ Y+ IY Y G + +NP++ L +Y+ + Y G K
Sbjct: 88 IEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKK 147
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR-- 457
R +PPHIF+++D YQ M+T +Q I+I+GESGAGKT N ++Q + +
Sbjct: 148 RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKK 207
Query: 458 ----------TLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQIS 507
TL+++I+ N L+EAFGNA T+ NDNSSRFGK++ + F ++G + A I
Sbjct: 208 EEVTSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 508 EYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDI 567
YLLEKSRV Q E+++HIFY I + +K L L P D+ Q
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQIMSN--KKPDLIEMLLITTNP-----YDYAFVSQGE 320
Query: 568 MNNSFYKSQYELI--EQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSH 625
+ Q EL+ + +++GFT ++ SIY + A+++ GN++F E Q +
Sbjct: 321 ITVPSIDDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDG 380
Query: 626 ISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGR 685
+ A L + + +L +AL V E + + TV++ + A+AK +Y +
Sbjct: 381 TE---VADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDK 437
Query: 686 LFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYY 745
+F W+V IN L + + IG+LDI GFE F NS EQLCIN NE++Q ++
Sbjct: 438 MFLWMVTRINQQLD-----TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFF 492
Query: 746 NQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLV 805
N H+F EQ EY E ++ I++ + ++KPMG+ S+L+EE FPKATD +
Sbjct: 493 NHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFK 552
Query: 806 EK-FEGNL-KSQYFWRPK----RMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLL 859
K +E +L KS F +PK + E F + HYAG V YN +G+L KN+D L +V L
Sbjct: 553 NKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLY 612
Query: 860 RSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEA--TRHARE 917
+ S M+T L A G EA + +
Sbjct: 613 QKS------------------------------AMKTLALLFVGATGAEAEAGGGKKGGK 642
Query: 918 TTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGI 977
QTV++ FR +L L++ + PHFVRCI PN + + E VL QLR G+
Sbjct: 643 KKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGV 702
Query: 978 LETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRM--SPDTCATILEKAGLDN--WAL 1033
LE RI R GF RIL+A+F +RY +L + E + S +L +D+ +
Sbjct: 703 LEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKF 762
Query: 1034 GKTKVFLKYYHVEQLNLMRKEAIDKLIL-IQACVRAFLCSRRYQKIQEKRKESAIIIQSA 1092
G TKVF K + L MR E + +LI QA R FL YQK+ E R+ES IQ
Sbjct: 763 GHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLARVEYQKMVE-RRESIFCIQYN 821
Query: 1093 ARGHLVRKQ--RKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISANER 1150
R + K ++ + + +T + + K+ FE T+E K +A+ E+
Sbjct: 822 VRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRK-ELEEK 880
Query: 1151 FISAPNNKG----SVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYL 1206
++ K V S EE +++ ++ K++ E+E + L
Sbjct: 881 MVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAEL 940
Query: 1207 VG------PEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYL-- 1258
E S +K + DLE L KVEKE+ ++ + TEE + A L
Sbjct: 941 TAKKRKLEDECSELKKDIDDLE--LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK 998
Query: 1259 ERKAISERPSYPVPWLAENETSFKKTLEPTLS-QRSIYQNANSMEKEKKTSVVTQRAPIC 1317
E+KA+ E + L E + + ++ + S+E+EKK + +RA
Sbjct: 999 EKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK-- 1056
Query: 1318 SQEEGRGRLRHETVKERQVEPVTQAQEEEDKAAVFIQS 1355
+ EG +L E+ + +E Q +E+ K F S
Sbjct: 1057 RKLEGDLKLAQESTMD--IENDKQQLDEKLKKKEFEMS 1092
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 410 bits (1054), Expect = e-114
Identities = 322/1096 (29%), Positives = 519/1096 (47%), Gaps = 105/1096 (9%)
Query: 340 VDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
++D+A + L E V L++ Y+ IY Y G + +NP++ L +Y + Y G K
Sbjct: 88 IEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKK 147
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR-- 457
R +PPHIF+++D YQ M+T +Q I+I+GESGAGKT N ++Q + +
Sbjct: 148 RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKK 207
Query: 458 ----------TLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQIS 507
TL+++I+ N L+EAFGNA T+ NDNSSRFGK++ + F ++G + A I
Sbjct: 208 EEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 508 EYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDI 567
YLLEKSRV+ Q E+++HIFY I + +K +L L P D+ Q
Sbjct: 268 TYLLEKSRVVFQLKAERSYHIFYQITSN--KKPELIEMLLITTNP-----YDYPFVSQGE 320
Query: 568 MNNSFYKSQYELI--EQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSH 625
++ + Q EL+ + ++GFT E+ SIY + A+++ GN++F E Q +
Sbjct: 321 ISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDG 380
Query: 626 ISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGR 685
+ A L + + +L +AL V E + + TVE+ ++ A+AK +Y +
Sbjct: 381 TE---VADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEK 437
Query: 686 LFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYY 745
+F W+V IN L + + IG+LDI GFE F NS EQLCIN NE++Q ++
Sbjct: 438 MFLWMVARINQQLD-----TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFF 492
Query: 746 NQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLV 805
N H+F EQ EY E ++ I++ + ++KPMG+ S+L+EE FPKATD +
Sbjct: 493 NHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFK 552
Query: 806 EK-FEGNL-KSQYFWRPK----RMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLL 859
K ++ +L KS F +PK + E F + HYAG V YN +G+L KN+D L +V L
Sbjct: 553 NKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLY 612
Query: 860 RSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETT 919
+ S + QL + T G G + +
Sbjct: 613 QKSAMKTLAQLFSGAQTAEGE--------------------------GAGGGAKKGGKKK 646
Query: 920 NMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILE 979
QTV++ FR +L L++ + PHFVRCI PN + + E VL QLR G+LE
Sbjct: 647 GSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLE 706
Query: 980 TARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGLD----NWALGK 1035
RI R GF RIL+A+F +RY +L + E + A+ A +D + G
Sbjct: 707 GIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGH 766
Query: 1036 TKVFLKYYHVEQLNLMRKEAIDKLIL-IQACVRAFLCSRRYQKIQEKRKESAIIIQSAAR 1094
TKVF K + L MR + + +LI QA R FL YQ++ E R+E+ IQ R
Sbjct: 767 TKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVE-RREAIFCIQYNIR 825
Query: 1095 GHLVRKQ---RKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISANERF 1151
+ K K +K + + +T + K+ F+ ++ K +A+ E+
Sbjct: 826 SFMNVKHWPWMKLFFKIK-PLLKSAETEKEMATMKEEFQKIKDELAKSEAKRK-ELEEKM 883
Query: 1152 ISAPNNKG----SVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYLV 1207
++ K V EE +++ ++ K++ E+E + L
Sbjct: 884 VTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943
Query: 1208 G------PEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYL--E 1259
E S +K + DLE L KVEKE+ ++ + TEE + A L E
Sbjct: 944 AKKRKLEDECSELKKDIDDLE--LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKE 1001
Query: 1260 RKAISERPSYPVPWLAENETSFKKTLEPTLS-QRSIYQNANSMEKEKKTSVVTQRAPICS 1318
+KA+ E + L E + + ++ + S+E+EKK + +RA
Sbjct: 1002 KKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK--R 1059
Query: 1319 QEEGRGRLRHETV----------------KERQVEPVTQAQEEEDKAAVFIQSKYRGYKR 1362
+ EG +L E++ KE ++ + E+E + +Q K + +
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQA 1119
Query: 1363 RQQLRKDKMSSFKHQR 1378
R + ++++ + + R
Sbjct: 1120 RIEELEEEIEAERASR 1135
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 410 bits (1054), Expect = e-114
Identities = 322/1096 (29%), Positives = 519/1096 (47%), Gaps = 105/1096 (9%)
Query: 340 VDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
++D+A + L E V L++ Y+ IY Y G + +NP++ L +Y + Y G K
Sbjct: 88 IEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKK 147
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR-- 457
R +PPHIF+++D YQ M+T +Q I+I+GESGAGKT N ++Q + +
Sbjct: 148 RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKK 207
Query: 458 ----------TLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQIS 507
TL+++I+ N L+EAFGNA T+ NDNSSRFGK++ + F ++G + A I
Sbjct: 208 EEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267
Query: 508 EYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDI 567
YLLEKSRV+ Q E+++HIFY I + +K +L L P D+ Q
Sbjct: 268 TYLLEKSRVVFQLKAERSYHIFYQITSN--KKPELIEMLLITTNP-----YDYPFVSQGE 320
Query: 568 MNNSFYKSQYELI--EQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSH 625
++ + Q EL+ + ++GFT E+ SIY + A+++ GN++F E Q +
Sbjct: 321 ISVASIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDG 380
Query: 626 ISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGR 685
+ A L + + +L +AL V E + + TVE+ ++ A+AK +Y +
Sbjct: 381 TE---VADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEK 437
Query: 686 LFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYY 745
+F W+V IN L + + IG+LDI GFE F NS EQLCIN NE++Q ++
Sbjct: 438 MFLWMVARINQQLD-----TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFF 492
Query: 746 NQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLV 805
N H+F EQ EY E ++ I++ + ++KPMG+ S+L+EE FPKATD +
Sbjct: 493 NHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFK 552
Query: 806 EK-FEGNL-KSQYFWRPK----RMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLL 859
K ++ +L KS F +PK + E F + HYAG V YN +G+L KN+D L +V L
Sbjct: 553 NKLYDQHLGKSANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLY 612
Query: 860 RSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETT 919
+ S + QL + T G G + +
Sbjct: 613 QKSAMKTLAQLFSGAQTAEGE--------------------------GAGGGAKKGGKKK 646
Query: 920 NMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILE 979
QTV++ FR +L L++ + PHFVRCI PN + + E VL QLR G+LE
Sbjct: 647 GSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLE 706
Query: 980 TARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILEKAGLD----NWALGK 1035
RI R GF RIL+A+F +RY +L + E + A+ A +D + G
Sbjct: 707 GIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGH 766
Query: 1036 TKVFLKYYHVEQLNLMRKEAIDKLIL-IQACVRAFLCSRRYQKIQEKRKESAIIIQSAAR 1094
TKVF K + L MR + + +LI QA R FL YQ++ E R+E+ IQ R
Sbjct: 767 TKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVE-RREAIFCIQYNIR 825
Query: 1095 GHLVRKQ---RKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQAENAISANERF 1151
+ K K +K + + +T + K+ F+ ++ K +A+ E+
Sbjct: 826 SFMNVKHWPWMKLFFKIK-PLLKSAETEKEMATMKEEFQKIKDELAKSEAKRK-ELEEKM 883
Query: 1152 ISAPNNKG----SVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYLV 1207
++ K V EE +++ ++ K++ E+E + L
Sbjct: 884 VTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943
Query: 1208 G------PEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYL--E 1259
E S +K + DLE L KVEKE+ ++ + TEE + A L E
Sbjct: 944 AKKRKLEDECSELKKDIDDLE--LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKE 1001
Query: 1260 RKAISERPSYPVPWLAENETSFKKTLEPTLS-QRSIYQNANSMEKEKKTSVVTQRAPICS 1318
+KA+ E + L E + + ++ + S+E+EKK + +RA
Sbjct: 1002 KKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK--R 1059
Query: 1319 QEEGRGRLRHETV----------------KERQVEPVTQAQEEEDKAAVFIQSKYRGYKR 1362
+ EG +L E++ KE ++ + E+E + +Q K + +
Sbjct: 1060 KLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQA 1119
Query: 1363 RQQLRKDKMSSFKHQR 1378
R + ++++ + + R
Sbjct: 1120 RIEELEEEIEAERASR 1135
>gi|124494247 myosin IC isoform b [Homo sapiens]
Length = 1044
Score = 409 bits (1050), Expect = e-113
Identities = 267/786 (33%), Positives = 426/786 (54%), Gaps = 81/786 (10%)
Query: 340 VDDLATLE-ILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGS 398
V D LE E E L + + + IY Y+G +L+++NP++ L +YS +H + Y G
Sbjct: 29 VQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGV 88
Query: 399 KRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR- 457
PPH+FA+AD Y+++ T DQ ++ISGESGAGKTE L+Q A R
Sbjct: 89 SFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERG 148
Query: 458 -TLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRV 516
+++++LQ N ++EAFGNA T+ NDNSSRFGKY++++F GA VG I YLLEKSRV
Sbjct: 149 GAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRV 208
Query: 517 IHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPEN-KPPRYLQNDHLRTVQDIMNNSFYKS 575
+HQ GE+NFHIFY + G E++ L L N + YL V I + KS
Sbjct: 209 VHQNHGERNFHIFYQLLEG-GEEETLRRLGLERNPQSYLYLVKGQCAKVSSIND----KS 263
Query: 576 QYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALENC 635
++++ + VI FT +++ + SI+A++L++GNI F++ ++ + ++ L+
Sbjct: 264 DWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAA----NEESNAQVTTENQLKYL 319
Query: 636 ASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCIN 695
LL + L+EALT ++ +GE ++ P +E+A RDA+AK +Y R F+W+V IN
Sbjct: 320 TRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKIN 379
Query: 696 SLL--KHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWE 753
L K SPS + +G+LDI+GFE F+ NSFEQ CIN NE++Q + + E
Sbjct: 380 RSLASKDVESPSWRSTTV-LGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSE 438
Query: 754 QNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFP-KATDQTLVEKFEGNL 812
Q EY E + ++Y +N + D+ +K G++S+LDEE P +ATD T +EK E +
Sbjct: 439 QEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTV 498
Query: 813 KSQ-YFWRPKRMEL---------SFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSS 862
K +F K + F + HYAG+V Y+ +GFL KN D L ++ + SS
Sbjct: 499 KHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSS 558
Query: 863 DNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMK 922
N ++ Q + + S+K +
Sbjct: 559 KNPIMSQCFD--------------------RSELSDK---------------------KR 577
Query: 923 TQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETAR 982
+TVA+ F+ SL+ L+ + +P +VRCIKPN +Q ++D+ + Q++Y G+LE R
Sbjct: 578 PETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLR 637
Query: 983 IRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSP-DTCATILEKAGL--DNWALGKTKVF 1039
+RR GF++R + F++RY LC ++ P D A ++ G + + +G+TK+F
Sbjct: 638 VRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIF 697
Query: 1040 LKY----YHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARG 1095
+++ + E +R++++ IQA R F +++ ++ K SAI IQS RG
Sbjct: 698 IRFPKTLFATEDALEVRRQSL--ATKIQAAWRGFHWRQKFLRV----KRSAICIQSWWRG 751
Query: 1096 HLVRKQ 1101
L R++
Sbjct: 752 TLGRRK 757
>gi|124494238 myosin IC isoform a [Homo sapiens]
Length = 1063
Score = 409 bits (1050), Expect = e-113
Identities = 267/786 (33%), Positives = 426/786 (54%), Gaps = 81/786 (10%)
Query: 340 VDDLATLE-ILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGS 398
V D LE E E L + + + IY Y+G +L+++NP++ L +YS +H + Y G
Sbjct: 48 VQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGV 107
Query: 399 KRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR- 457
PPH+FA+AD Y+++ T DQ ++ISGESGAGKTE L+Q A R
Sbjct: 108 SFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERG 167
Query: 458 -TLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRV 516
+++++LQ N ++EAFGNA T+ NDNSSRFGKY++++F GA VG I YLLEKSRV
Sbjct: 168 GAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRV 227
Query: 517 IHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPEN-KPPRYLQNDHLRTVQDIMNNSFYKS 575
+HQ GE+NFHIFY + G E++ L L N + YL V I + KS
Sbjct: 228 VHQNHGERNFHIFYQLLEG-GEEETLRRLGLERNPQSYLYLVKGQCAKVSSIND----KS 282
Query: 576 QYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALENC 635
++++ + VI FT +++ + SI+A++L++GNI F++ ++ + ++ L+
Sbjct: 283 DWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAA----NEESNAQVTTENQLKYL 338
Query: 636 ASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCIN 695
LL + L+EALT ++ +GE ++ P +E+A RDA+AK +Y R F+W+V IN
Sbjct: 339 TRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKIN 398
Query: 696 SLL--KHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWE 753
L K SPS + +G+LDI+GFE F+ NSFEQ CIN NE++Q + + E
Sbjct: 399 RSLASKDVESPSWRSTTV-LGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSE 457
Query: 754 QNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFP-KATDQTLVEKFEGNL 812
Q EY E + ++Y +N + D+ +K G++S+LDEE P +ATD T +EK E +
Sbjct: 458 QEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTV 517
Query: 813 KSQ-YFWRPKRMEL---------SFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSS 862
K +F K + F + HYAG+V Y+ +GFL KN D L ++ + SS
Sbjct: 518 KHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSS 577
Query: 863 DNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMK 922
N ++ Q + + S+K +
Sbjct: 578 KNPIMSQCFD--------------------RSELSDK---------------------KR 596
Query: 923 TQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETAR 982
+TVA+ F+ SL+ L+ + +P +VRCIKPN +Q ++D+ + Q++Y G+LE R
Sbjct: 597 PETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLR 656
Query: 983 IRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSP-DTCATILEKAGL--DNWALGKTKVF 1039
+RR GF++R + F++RY LC ++ P D A ++ G + + +G+TK+F
Sbjct: 657 VRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIF 716
Query: 1040 LKY----YHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARG 1095
+++ + E +R++++ IQA R F +++ ++ K SAI IQS RG
Sbjct: 717 IRFPKTLFATEDALEVRRQSL--ATKIQAAWRGFHWRQKFLRV----KRSAICIQSWWRG 770
Query: 1096 HLVRKQ 1101
L R++
Sbjct: 771 TLGRRK 776
>gi|124494240 myosin IC isoform c [Homo sapiens]
Length = 1028
Score = 409 bits (1050), Expect = e-113
Identities = 267/786 (33%), Positives = 426/786 (54%), Gaps = 81/786 (10%)
Query: 340 VDDLATLE-ILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGS 398
V D LE E E L + + + IY Y+G +L+++NP++ L +YS +H + Y G
Sbjct: 13 VQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGV 72
Query: 399 KRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR- 457
PPH+FA+AD Y+++ T DQ ++ISGESGAGKTE L+Q A R
Sbjct: 73 SFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERG 132
Query: 458 -TLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRV 516
+++++LQ N ++EAFGNA T+ NDNSSRFGKY++++F GA VG I YLLEKSRV
Sbjct: 133 GAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRV 192
Query: 517 IHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPEN-KPPRYLQNDHLRTVQDIMNNSFYKS 575
+HQ GE+NFHIFY + G E++ L L N + YL V I + KS
Sbjct: 193 VHQNHGERNFHIFYQLLEG-GEEETLRRLGLERNPQSYLYLVKGQCAKVSSIND----KS 247
Query: 576 QYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALENC 635
++++ + VI FT +++ + SI+A++L++GNI F++ ++ + ++ L+
Sbjct: 248 DWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAA----NEESNAQVTTENQLKYL 303
Query: 636 ASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCIN 695
LL + L+EALT ++ +GE ++ P +E+A RDA+AK +Y R F+W+V IN
Sbjct: 304 TRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKIN 363
Query: 696 SLL--KHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWE 753
L K SPS + +G+LDI+GFE F+ NSFEQ CIN NE++Q + + E
Sbjct: 364 RSLASKDVESPSWRSTTV-LGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSE 422
Query: 754 QNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFP-KATDQTLVEKFEGNL 812
Q EY E + ++Y +N + D+ +K G++S+LDEE P +ATD T +EK E +
Sbjct: 423 QEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTV 482
Query: 813 KSQ-YFWRPKRMEL---------SFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSS 862
K +F K + F + HYAG+V Y+ +GFL KN D L ++ + SS
Sbjct: 483 KHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSS 542
Query: 863 DNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARETTNMK 922
N ++ Q + + S+K +
Sbjct: 543 KNPIMSQCFD--------------------RSELSDK---------------------KR 561
Query: 923 TQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETAR 982
+TVA+ F+ SL+ L+ + +P +VRCIKPN +Q ++D+ + Q++Y G+LE R
Sbjct: 562 PETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLR 621
Query: 983 IRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSP-DTCATILEKAGL--DNWALGKTKVF 1039
+RR GF++R + F++RY LC ++ P D A ++ G + + +G+TK+F
Sbjct: 622 VRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIF 681
Query: 1040 LKY----YHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARG 1095
+++ + E +R++++ IQA R F +++ ++ K SAI IQS RG
Sbjct: 682 IRFPKTLFATEDALEVRRQSL--ATKIQAAWRGFHWRQKFLRV----KRSAICIQSWWRG 735
Query: 1096 HLVRKQ 1101
L R++
Sbjct: 736 TLGRRK 741
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 406 bits (1044), Expect = e-113
Identities = 316/1070 (29%), Positives = 511/1070 (47%), Gaps = 90/1070 (8%)
Query: 315 EKARRERIHTKKGNFNRPLISNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDI 374
E A E + K+ + + ++D+A L L+E +V L++ Y + IY Y G
Sbjct: 80 ETADGESLSIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLF 139
Query: 375 LIALNPFQSLGLYSTKHSKLYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESG 434
+ +NP++ L +Y + Y G +R+ +PPHIFA+A+ +Q M+ +Q I+ +GESG
Sbjct: 140 CVTINPYKWLPVYQKEVMAAYKGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESG 199
Query: 435 AGKTENAHLLVQQLTVLG-----KANNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGK 489
AGKT N+ ++Q + + L+++I+Q N ++EAFGNA T+ NDNSSRFGK
Sbjct: 200 AGKTVNSKHIIQYFATIAAMIESRKKQGALEDQIMQANTILEAFGNAKTLRNDNSSRFGK 259
Query: 490 YLEMKFTSSGAVVGAQISEYLLEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPE 549
++ M F + G + I YLLEKSRVI Q GE+N+HIFY I +G +K+L L
Sbjct: 260 FIRMHFGARGMLSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSG---QKELHDLLLVS 316
Query: 550 NKPPRYLQNDHLRTVQDIMNNSFYKSQYEL-IEQCFKVIGFTMEQLGSIYSILAAILNVG 608
P + H + + S ++ L EQ ++GF ++ Y + AI++ G
Sbjct: 317 ANPSDF----HFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFG 372
Query: 609 NIEFSSVATEHQIDKSHISNHTALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTV 668
N++F E Q++ N + A L+ I + EL + L + E + R T+
Sbjct: 373 NMKFKQKPREEQLEADGTEN---ADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTI 429
Query: 669 EKATDVRDAMAKTLYGRLFSWIVNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNS 728
E+ T A++K++Y R+F W+V IN L S + IGILDI GFE + NS
Sbjct: 430 EQVTCAVGALSKSMYERMFKWLVARINRALDAKLS-----RQFFIGILDITGFEILEYNS 484
Query: 729 FEQLCINIANEQIQYYYNQHVFAWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLS 788
EQLCIN NE++Q ++N H+F EQ EY E ++ I + + ++KPMG+LS
Sbjct: 485 LEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACIDLIEKPMGILS 544
Query: 789 LLDEESRFPKATDQTLVEKFEGNL--KSQYFWRP----KRMELSFGIHHYAGKVLYNASG 842
+L+EE FPKATD T K N KS + +P K+ E F + HYAG V YN SG
Sbjct: 545 ILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKKKFEAHFELVHYAGVVPYNISG 604
Query: 843 FLAKNRDTLPTDIVLLLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLIN 902
+L KN+D L +V + + S N ++ L + ++ +P + K
Sbjct: 605 WLEKNKDLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKR-------------- 650
Query: 903 LAKGDTGEATRHARETTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARK 962
KG QTVAS + +L L++ + PHFVRCI PN +
Sbjct: 651 -KKG--------------ASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIPGI 695
Query: 963 YDKEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRM--SPDTCA 1020
D VL QLR G+LE RI R GF +R+ +A+F +RY +L ++ + + S
Sbjct: 696 LDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKAAE 755
Query: 1021 TILEKAGLDN--WALGKTKVFLKYYHVEQLNLMRKEAIDKLI-LIQACVRAFLCSRRYQK 1077
+L +D+ + G TKVF K + QL +R E + K+ L QA + L ++QK
Sbjct: 756 ELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQK 815
Query: 1078 IQEKRKESAIIIQSAARGHLVRK---------QRKEIVDMKNTAVTTIQTSDQEFDYKKN 1128
I E+R ++ I+IQ R + K + K +V ++ +K
Sbjct: 816 ILEER-DALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKA 874
Query: 1129 FENT---RESFVKKQAENAISANERFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRV 1185
E + RE KQ N+ + + +++ V+ E + ++ RV
Sbjct: 875 LEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQC---EWLIKSKIQLEARV 931
Query: 1186 YQTPKKMNNVYEEEVKQEFYLVGPEVSPK----QKSVKDLEENSNLRKVEKEEAMIQSYY 1241
+ +++ EEE+ E G ++ + +K + DLE + L K EKE+ +
Sbjct: 932 KELSERVEE--EEEINSELTARGRKLEDECFELKKEIDDLE--TMLVKSEKEKRTTEHKV 987
Query: 1242 QRYTEERNCEESKAAYLER--KAISERPSYPVPWLAENETSFKKTLEPTLS-QRSIYQNA 1298
+ TEE + L R K + E + L E + L ++ + +
Sbjct: 988 KNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELE 1047
Query: 1299 NSMEKEKKTSVVTQRAPICSQEEGRGRLRHETVKERQVEPVTQAQEEEDK 1348
++E+E+K + +R + EG +L E+++ + A+E K
Sbjct: 1048 GALEQERKARMNCERE--LHKLEGNLKLNRESMENLESSQRHLAEELRKK 1095
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 406 bits (1043), Expect = e-112
Identities = 331/1188 (27%), Positives = 563/1188 (47%), Gaps = 128/1188 (10%)
Query: 340 VDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
V+D+A L L+E +V L + Y IY Y G + +NP++ L +YS K +Y G K
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRT- 458
R PPHI+A+AD Y+SM+ DQ I+ +GESGAGKTEN ++Q L V+ ++
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 459 -------LQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLL 511
L++++LQ N ++EAFGNA T+ NDNSSRFGK++ + F +G +VGA I YLL
Sbjct: 207 DTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266
Query: 512 EKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNS 571
EKSR I QA E+ FHIFYY+ AG EK + + L +L N + + ++
Sbjct: 267 EKSRAIRQARDERTFHIFYYMIAGAKEKMR-SDLLLEGFNNYTFLSNGFV-PIPAAQDDE 324
Query: 572 FYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTA 631
++ E ++GF+ E+ SI +++++L +GNI F E D++ + ++TA
Sbjct: 325 MFQETVE----AMAIMGFSEEEQLSILKVVSSVLQLGNIVFKK---ERNTDQASMPDNTA 377
Query: 632 LENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIV 691
+ L+ I + ++ + + + + + T E+A +A+AK Y RLF WI+
Sbjct: 378 AQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWIL 437
Query: 692 NCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFA 751
+N L + +GILDI GFE F+ NSFEQLCIN NE++Q +N +F
Sbjct: 438 TRVNKALDKTHRQGAS----FLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFI 493
Query: 752 WEQNEYLNEDVDARVIEYE-DNWPLLDMFLQ--KPMGLLSLLDEESRFPKATDQTLVEKF 808
EQ EY E ++ I++ D P +++ + P G+L+LLDEE FPKATD++ VEK
Sbjct: 494 LEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKL 553
Query: 809 EGNLKSQ-YFWRPKRM--ELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNS 865
S F +PK++ + F I HYAGKV YNAS +L KN D L ++ LL +S +
Sbjct: 554 CTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDK 613
Query: 866 VIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAK--GDTGEATRHARETTNMKT 923
+ L + ++++ L + T + A +T
Sbjct: 614 FVADL-----------------------WKDVDRIVGLDQMAKMTESSLPSASKTKKGMF 650
Query: 924 QTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARI 983
+TV ++ L L++ + P+FVRCI PN E+++ K D VL QLR G+LE RI
Sbjct: 651 RTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRI 710
Query: 984 RRLGFSHRILFANFIKRYYLLCYKSSEEPRM-SPDTCATILEKAGLDN--WALGKTKVFL 1040
R GF +RI+F F +RY +L + + M C +++ LD + +G++K+F
Sbjct: 711 CRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFF 770
Query: 1041 KYYHVEQLNLMRKEAI-DKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVR 1099
+ + L R I D ++ QA R +L + + K Q++ +I ++ A +R
Sbjct: 771 RTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLR 830
Query: 1100 KQRKEIVDMKNTAVTTIQTSDQEFDYKKN-FENTRESFVKKQAENAISANERFISAPNNK 1158
+ + K + + ++E K++ + T+E +++AEN + E+ S +
Sbjct: 831 NWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER--QQKAENELKELEQKHSQLTEE 888
Query: 1159 GSV-----------------SVVKTSTFKPE------EETTNAVESNNRVYQTPKKMNNV 1195
++ V+ + K E E E +R Q + +
Sbjct: 889 KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM 948
Query: 1196 YEEEVKQEFYLVGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKA 1255
++ + E L E + ++ ++ + + ++K+E E ++ + ++ER E +
Sbjct: 949 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1008
Query: 1256 AYLERKAISERPSYPVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAP 1315
+ L E A+N T K E +S+ + ++KE+K+ ++
Sbjct: 1009 SDLTTNLAEEEEK------AKNLTKLKNKHESMISELEV-----RLKKEEKSRQELEK-- 1055
Query: 1316 ICSQEEGRGRLRHETVKERQVE----PVTQAQEEEDKAAVF------IQSKYRGYKRRQQ 1365
+ + EG HE + + Q + + A++EE+ A I K K+ ++
Sbjct: 1056 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE 1115
Query: 1366 LR---KDKMSSFKHQRIVTTPTEVARNTHNLYSYPTKHEEINNIKK--KDNKDSKATSER 1420
L D +R E + EE+ +K +D DS AT +
Sbjct: 1116 LEGHISDLQEDLDSERAARNKAEKQKRDLG--------EELEALKTELEDTLDSTATQQ- 1166
Query: 1421 EACGLAIFSKQISKLSEEYFILQKKLNEMILSQQLKSLYLGVSHHKPI 1468
+ +K +E +L+K L+E S + + + H + +
Sbjct: 1167 ---------ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Score = 42.7 bits (99), Expect = 0.003
Identities = 94/435 (21%), Positives = 167/435 (38%), Gaps = 75/435 (17%)
Query: 1037 KVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGH 1096
KV VE + M EA K I + V + S + Q QE ++Q R
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL--SSQLQDTQE-------LLQEETRQK 1331
Query: 1097 L-VRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFE------NTRESFVKKQAENAISANE 1149
L V + +++ + +N+ + D+E + K+N E N + S KK+ ++ S E
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQL---DEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVE 1388
Query: 1150 RFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYLVGP 1209
++ K K E T E Y +K N ++E+ +
Sbjct: 1389 ----------ALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD----LVV 1434
Query: 1210 EVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERKAISERPSY 1269
++ +++ V +LE+ RK ++ A ++ +Y +ER+ E++A E KA+
Sbjct: 1435 DLDNQRQLVSNLEKKQ--RKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL------ 1486
Query: 1270 PVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAPICSQEEGRGRLRHE 1329
S + LE L + + N M K + +V S ++ G+ HE
Sbjct: 1487 ----------SLARALEEALEAKEELERTNKMLKAEMEDLV-------SSKDDVGKNVHE 1529
Query: 1330 TVKERQV------EPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIVTTP 1383
K ++ E TQ +E ED+ +K R + Q K + R
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLR-LEVNMQALKGQFERDLQARDEQNE 1588
Query: 1384 TEVARNTHNLYSYPTKHEEINN-------IKKK---DNKDSKATSEREACGLAIFSKQIS 1433
+ + L+ Y T+ E+ KKK D KD + ++ G KQ+
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 1434 KLSEEYFILQKKLNE 1448
KL + Q++L +
Sbjct: 1649 KLQAQMKDFQRELED 1663
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 406 bits (1043), Expect = e-112
Identities = 331/1188 (27%), Positives = 563/1188 (47%), Gaps = 128/1188 (10%)
Query: 340 VDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSK 399
V+D+A L L+E +V L + Y IY Y G + +NP++ L +YS K +Y G K
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 400 RTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRT- 458
R PPHI+A+AD Y+SM+ DQ I+ +GESGAGKTEN ++Q L V+ ++
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 459 -------LQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLL 511
L++++LQ N ++EAFGNA T+ NDNSSRFGK++ + F +G +VGA I YLL
Sbjct: 207 DTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266
Query: 512 EKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNS 571
EKSR I QA E+ FHIFYY+ AG EK + + L +L N + + ++
Sbjct: 267 EKSRAIRQARDERTFHIFYYMIAGAKEKMR-SDLLLEGFNNYTFLSNGFV-PIPAAQDDE 324
Query: 572 FYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTA 631
++ E ++GF+ E+ SI +++++L +GNI F E D++ + ++TA
Sbjct: 325 MFQETVE----AMAIMGFSEEEQLSILKVVSSVLQLGNIVFKK---ERNTDQASMPDNTA 377
Query: 632 LENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIV 691
+ L+ I + ++ + + + + + T E+A +A+AK Y RLF WI+
Sbjct: 378 AQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWIL 437
Query: 692 NCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFA 751
+N L + +GILDI GFE F+ NSFEQLCIN NE++Q +N +F
Sbjct: 438 TRVNKALDKTHRQGAS----FLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFI 493
Query: 752 WEQNEYLNEDVDARVIEYE-DNWPLLDMFLQ--KPMGLLSLLDEESRFPKATDQTLVEKF 808
EQ EY E ++ I++ D P +++ + P G+L+LLDEE FPKATD++ VEK
Sbjct: 494 LEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKL 553
Query: 809 EGNLKSQ-YFWRPKRM--ELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNS 865
S F +PK++ + F I HYAGKV YNAS +L KN D L ++ LL +S +
Sbjct: 554 CTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDK 613
Query: 866 VIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAK--GDTGEATRHARETTNMKT 923
+ L + ++++ L + T + A +T
Sbjct: 614 FVADL-----------------------WKDVDRIVGLDQMAKMTESSLPSASKTKKGMF 650
Query: 924 QTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGILETARI 983
+TV ++ L L++ + P+FVRCI PN E+++ K D VL QLR G+LE RI
Sbjct: 651 RTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRI 710
Query: 984 RRLGFSHRILFANFIKRYYLLCYKSSEEPRM-SPDTCATILEKAGLDN--WALGKTKVFL 1040
R GF +RI+F F +RY +L + + M C +++ LD + +G++K+F
Sbjct: 711 CRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFF 770
Query: 1041 KYYHVEQLNLMRKEAI-DKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGHLVR 1099
+ + L R I D ++ QA R +L + + K Q++ +I ++ A +R
Sbjct: 771 RTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLR 830
Query: 1100 KQRKEIVDMKNTAVTTIQTSDQEFDYKKN-FENTRESFVKKQAENAISANERFISAPNNK 1158
+ + K + + ++E K++ + T+E +++AEN + E+ S +
Sbjct: 831 NWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER--QQKAENELKELEQKHSQLTEE 888
Query: 1159 GSV-----------------SVVKTSTFKPE------EETTNAVESNNRVYQTPKKMNNV 1195
++ V+ + K E E E +R Q + +
Sbjct: 889 KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM 948
Query: 1196 YEEEVKQEFYLVGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKA 1255
++ + E L E + ++ ++ + + ++K+E E ++ + ++ER E +
Sbjct: 949 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1008
Query: 1256 AYLERKAISERPSYPVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAP 1315
+ L E A+N T K E +S+ + ++KE+K+ ++
Sbjct: 1009 SDLTTNLAEEEEK------AKNLTKLKNKHESMISELEV-----RLKKEEKSRQELEK-- 1055
Query: 1316 ICSQEEGRGRLRHETVKERQVE----PVTQAQEEEDKAAVF------IQSKYRGYKRRQQ 1365
+ + EG HE + + Q + + A++EE+ A I K K+ ++
Sbjct: 1056 LKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRE 1115
Query: 1366 LR---KDKMSSFKHQRIVTTPTEVARNTHNLYSYPTKHEEINNIKK--KDNKDSKATSER 1420
L D +R E + EE+ +K +D DS AT +
Sbjct: 1116 LEGHISDLQEDLDSERAARNKAEKQKRDLG--------EELEALKTELEDTLDSTATQQ- 1166
Query: 1421 EACGLAIFSKQISKLSEEYFILQKKLNEMILSQQLKSLYLGVSHHKPI 1468
+ +K +E +L+K L+E S + + + H + +
Sbjct: 1167 ---------ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Score = 42.7 bits (99), Expect = 0.003
Identities = 94/435 (21%), Positives = 167/435 (38%), Gaps = 75/435 (17%)
Query: 1037 KVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQEKRKESAIIIQSAARGH 1096
KV VE + M EA K I + V + S + Q QE ++Q R
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL--SSQLQDTQE-------LLQEETRQK 1331
Query: 1097 L-VRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFE------NTRESFVKKQAENAISANE 1149
L V + +++ + +N+ + D+E + K+N E N + S KK+ ++ S E
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQL---DEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVE 1388
Query: 1150 RFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVKQEFYLVGP 1209
++ K K E T E Y +K N ++E+ +
Sbjct: 1389 ----------ALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD----LVV 1434
Query: 1210 EVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERKAISERPSY 1269
++ +++ V +LE+ RK ++ A ++ +Y +ER+ E++A E KA+
Sbjct: 1435 DLDNQRQLVSNLEKKQ--RKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL------ 1486
Query: 1270 PVPWLAENETSFKKTLEPTLSQRSIYQNANSMEKEKKTSVVTQRAPICSQEEGRGRLRHE 1329
S + LE L + + N M K + +V S ++ G+ HE
Sbjct: 1487 ----------SLARALEEALEAKEELERTNKMLKAEMEDLV-------SSKDDVGKNVHE 1529
Query: 1330 TVKERQV------EPVTQAQEEEDKAAVFIQSKYRGYKRRQQLRKDKMSSFKHQRIVTTP 1383
K ++ E TQ +E ED+ +K R + Q K + R
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLR-LEVNMQALKGQFERDLQARDEQNE 1588
Query: 1384 TEVARNTHNLYSYPTKHEEINN-------IKKK---DNKDSKATSEREACGLAIFSKQIS 1433
+ + L+ Y T+ E+ KKK D KD + ++ G KQ+
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 1434 KLSEEYFILQKKLNE 1448
KL + Q++L +
Sbjct: 1649 KLQAQMKDFQRELED 1663
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 405 bits (1042), Expect = e-112
Identities = 276/853 (32%), Positives = 435/853 (50%), Gaps = 95/853 (11%)
Query: 333 LISNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHS 392
L+ N+ V D+ LE L+E T L+K + +IY Y+G ++I++NP++SL +YS +
Sbjct: 10 LLDNMIGVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKV 69
Query: 393 KLYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQL-TVL 451
+ Y PHIFA++D Y+S+ + DQCI+I+GESGAGKTE + L++ + V
Sbjct: 70 EEYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVC 129
Query: 452 GK-ANNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYL 510
GK A ++E++LQ N ++EAFGNA T+ NDNSSRFGKY++++F G +G IS YL
Sbjct: 130 GKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYL 189
Query: 511 LEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNN 570
LEKSRV+ Q GE+NFH+FY + +G A ++ L KL + + + ++L +N
Sbjct: 190 LEKSRVVKQPRGERNFHVFYQLLSG-ASEELLNKLKLERD----FSRYNYLSLDSAKVNG 244
Query: 571 SFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHT 630
+ + + +++GF + S+ +++AA+L +GNIEF + + +D+S I +
Sbjct: 245 VDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKN 304
Query: 631 ALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWI 690
L+ L I L+ A + V + E + V +A RDA+AK LY RLFSW+
Sbjct: 305 ELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWL 364
Query: 691 VNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVF 750
VN IN +K + + +G+LDI+GFE F+ NSFEQ IN NE++Q + +
Sbjct: 365 VNRINESIKAQTKVR----KKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTL 420
Query: 751 AWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFP-KATDQTLVEK-- 807
EQ EY+ ED++ I+Y +N + D+ G+L++LDEE P TD+T +EK
Sbjct: 421 KEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLN 480
Query: 808 --------FEGNLK--SQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVL 857
FE + S++ F I HYAGKVLY GF+ KN D L D+
Sbjct: 481 QVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQ 540
Query: 858 LLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARE 917
+ + +++I+ L GN INL
Sbjct: 541 AMWKASHALIKSLF-----PEGN-----------------PAKINL-------------- 564
Query: 918 TTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGI 977
+ T S F+ S+ L+ + P+++RCIKPN ++ A +++ V Q+RY G+
Sbjct: 565 ---KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGL 621
Query: 978 LETARIRRLGFSHRILFANFIKRYYLLCYKS----SEEPRMSPDTCATILEKAGLDNWAL 1033
LE R+RR G++ R + ++RY +LC ++ R + LE ++ ++
Sbjct: 622 LENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELE-IPVEEYSF 680
Query: 1034 GKTKVFLK----YYHVEQLNLMRKEAIDKLILIQACVRAFLCS----------------- 1072
G++K+F++ + +E L R E D LIQ R + C
Sbjct: 681 GRSKIFIRNPRTLFKLEDLRKQRLE--DLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWY 738
Query: 1073 RRY--QKIQEKRKESAIIIQSAARGHLVRKQRKEIVDMK--NTAVTTIQTSDQEFDYKKN 1128
RRY QK ++ K SA++IQS RG RK +E+ K AVTTI ++
Sbjct: 739 RRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRE 798
Query: 1129 FENTRESFVKKQA 1141
+E K A
Sbjct: 799 LRRLKEEARNKHA 811
>gi|240120050 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 405 bits (1042), Expect = e-112
Identities = 276/853 (32%), Positives = 435/853 (50%), Gaps = 95/853 (11%)
Query: 333 LISNLKDVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHS 392
L+ N+ V D+ LE L+E T L+K + +IY Y+G ++I++NP++SL +YS +
Sbjct: 10 LLDNMIGVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKV 69
Query: 393 KLYIGSKRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQL-TVL 451
+ Y PHIFA++D Y+S+ + DQCI+I+GESGAGKTE + L++ + V
Sbjct: 70 EEYRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVC 129
Query: 452 GK-ANNRTLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYL 510
GK A ++E++LQ N ++EAFGNA T+ NDNSSRFGKY++++F G +G IS YL
Sbjct: 130 GKGAEVNQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYL 189
Query: 511 LEKSRVIHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNN 570
LEKSRV+ Q GE+NFH+FY + +G A ++ L KL + + + ++L +N
Sbjct: 190 LEKSRVVKQPRGERNFHVFYQLLSG-ASEELLNKLKLERD----FSRYNYLSLDSAKVNG 244
Query: 571 SFYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHT 630
+ + + +++GF + S+ +++AA+L +GNIEF + + +D+S I +
Sbjct: 245 VDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKN 304
Query: 631 ALENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWI 690
L+ L I L+ A + V + E + V +A RDA+AK LY RLFSW+
Sbjct: 305 ELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWL 364
Query: 691 VNCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVF 750
VN IN +K + + +G+LDI+GFE F+ NSFEQ IN NE++Q + +
Sbjct: 365 VNRINESIKAQTKVR----KKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTL 420
Query: 751 AWEQNEYLNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFP-KATDQTLVEK-- 807
EQ EY+ ED++ I+Y +N + D+ G+L++LDEE P TD+T +EK
Sbjct: 421 KEEQEEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLN 480
Query: 808 --------FEGNLK--SQYFWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVL 857
FE + S++ F I HYAGKVLY GF+ KN D L D+
Sbjct: 481 QVCATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQ 540
Query: 858 LLRSSDNSVIRQLVNHPLTKTGNLPHSKTKNVINYQMRTSEKLINLAKGDTGEATRHARE 917
+ + +++I+ L GN INL
Sbjct: 541 AMWKASHALIKSLF-----PEGN-----------------PAKINL-------------- 564
Query: 918 TTNMKTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYDKEKVLLQLRYTGI 977
+ T S F+ S+ L+ + P+++RCIKPN ++ A +++ V Q+RY G+
Sbjct: 565 ---KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGL 621
Query: 978 LETARIRRLGFSHRILFANFIKRYYLLCYKS----SEEPRMSPDTCATILEKAGLDNWAL 1033
LE R+RR G++ R + ++RY +LC ++ R + LE ++ ++
Sbjct: 622 LENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELE-IPVEEYSF 680
Query: 1034 GKTKVFLK----YYHVEQLNLMRKEAIDKLILIQACVRAFLCS----------------- 1072
G++K+F++ + +E L R E D LIQ R + C
Sbjct: 681 GRSKIFIRNPRTLFKLEDLRKQRLE--DLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWY 738
Query: 1073 RRY--QKIQEKRKESAIIIQSAARGHLVRKQRKEIVDMK--NTAVTTIQTSDQEFDYKKN 1128
RRY QK ++ K SA++IQS RG RK +E+ K AVTTI ++
Sbjct: 739 RRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRE 798
Query: 1129 FENTRESFVKKQA 1141
+E K A
Sbjct: 799 LRRLKEEARNKHA 811
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,392,994
Number of Sequences: 37866
Number of extensions: 2792364
Number of successful extensions: 12425
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 658
Number of HSP's successfully gapped in prelim test: 380
Number of HSP's that attempted gapping in prelim test: 8681
Number of HSP's gapped (non-prelim): 2233
length of query: 1616
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1500
effective length of database: 13,855,062
effective search space: 20782593000
effective search space used: 20782593000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.