Guide to the Human Genome
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Search of human proteins with 145275189

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|145275189 specifically androgen-regulated protein isoform 1
[Homo sapiens]
         (601 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|145275189 specifically androgen-regulated protein isoform 1 [...  1199   0.0  
gi|145275193 specifically androgen-regulated protein isoform 2 [...   704   0.0  
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    78   3e-14
gi|150170670 piccolo isoform 2 [Homo sapiens]                          73   9e-13
gi|150378539 piccolo isoform 1 [Homo sapiens]                          73   9e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni...    70   4e-12
gi|91982772 mucin 17 [Homo sapiens]                                    67   5e-11
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   65   2e-10
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    65   2e-10
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         63   9e-10
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             62   2e-09
gi|226437579 NAC alpha domain containing [Homo sapiens]                60   4e-09
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]     60   4e-09
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   60   6e-09
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   60   6e-09
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    60   6e-09
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             60   7e-09
gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]     59   1e-08
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       59   1e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    59   2e-08
gi|41281612 zinc finger protein 828 [Homo sapiens]                     59   2e-08
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]     58   2e-08
gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]     58   2e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    58   3e-08
gi|11641239 hypothetical protein LOC53838 [Homo sapiens]               57   4e-08
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    57   5e-08
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       57   5e-08
gi|223633935 hypothetical protein LOC254427 [Homo sapiens]             56   8e-08
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]          55   2e-07
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ...    55   2e-07

>gi|145275189 specifically androgen-regulated protein isoform 1
           [Homo sapiens]
          Length = 601

 Score = 1199 bits (3101), Expect = 0.0
 Identities = 601/601 (100%), Positives = 601/601 (100%)

Query: 1   MPERELWPAGTGSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGS 60
           MPERELWPAGTGSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGS
Sbjct: 1   MPERELWPAGTGSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGS 60

Query: 61  LDTEADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPP 120
           LDTEADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPP
Sbjct: 61  LDTEADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPP 120

Query: 121 EPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPR 180
           EPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPR
Sbjct: 121 EPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPR 180

Query: 181 QAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQERE 240
           QAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQERE
Sbjct: 181 QAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQERE 240

Query: 241 QTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRK 300
           QTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRK
Sbjct: 241 QTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRK 300

Query: 301 LPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQ 360
           LPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQ
Sbjct: 301 LPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQ 360

Query: 361 DEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGP 420
           DEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGP
Sbjct: 361 DEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGP 420

Query: 421 AQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPGLRQMNFK 480
           AQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPGLRQMNFK
Sbjct: 421 AQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPGLRQMNFK 480

Query: 481 SNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPASLGTGKDFA 540
           SNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPASLGTGKDFA
Sbjct: 481 SNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPASLGTGKDFA 540

Query: 541 GIQVGKLADLEQEQSSKRLSYQGQSRDKLPRPPCVSVKISPKGVPNEHRREALKKLGLLK 600
           GIQVGKLADLEQEQSSKRLSYQGQSRDKLPRPPCVSVKISPKGVPNEHRREALKKLGLLK
Sbjct: 541 GIQVGKLADLEQEQSSKRLSYQGQSRDKLPRPPCVSVKISPKGVPNEHRREALKKLGLLK 600

Query: 601 E 601
           E
Sbjct: 601 E 601


>gi|145275193 specifically androgen-regulated protein isoform 2
           [Homo sapiens]
          Length = 355

 Score =  704 bits (1818), Expect = 0.0
 Identities = 355/355 (100%), Positives = 355/355 (100%)

Query: 247 MSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIV 306
           MSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIV
Sbjct: 1   MSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIV 60

Query: 307 LKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLH 366
           LKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLH
Sbjct: 61  LKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLH 120

Query: 367 LSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLP 426
           LSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLP
Sbjct: 121 LSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLP 180

Query: 427 MKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLER 486
           MKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLER
Sbjct: 181 MKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLER 240

Query: 487 SGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPASLGTGKDFAGIQVGK 546
           SGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPASLGTGKDFAGIQVGK
Sbjct: 241 SGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPASLGTGKDFAGIQVGK 300

Query: 547 LADLEQEQSSKRLSYQGQSRDKLPRPPCVSVKISPKGVPNEHRREALKKLGLLKE 601
           LADLEQEQSSKRLSYQGQSRDKLPRPPCVSVKISPKGVPNEHRREALKKLGLLKE
Sbjct: 301 LADLEQEQSSKRLSYQGQSRDKLPRPPCVSVKISPKGVPNEHRREALKKLGLLKE 355


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 112/426 (26%), Positives = 155/426 (36%), Gaps = 40/426 (9%)

Query: 65  ADSGLSTDESEPATTPRGFRALP-ITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQ 123
           A   L T  S PAT P   +A P +T P  +  P        + P ++T  S   PP P 
Sbjct: 350 APPSLQTLPSPPATPPS--QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL 407

Query: 124 GLGLRSGSYSLPRNIHIARSQNFRKST--TQASSHNPGEPGRLAPEPEKEQVSQSSQPRQ 181
            L     + SL      A       S   TQAS  +P  P    P+    Q      P  
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA-----PLS 462

Query: 182 APASPQ-EAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSS-SQER 239
            PASP  + +L   V  +  P      Q      +  P+ P      P L T SS +   
Sbjct: 463 LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPS 522

Query: 240 EQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPR 299
            QTP  +++    E + +      PPP       +   APL++   P+    P   P P 
Sbjct: 523 LQTPPASLTTPPLENLPSL----APPPL------QTASAPLTT---PHLETPPCPAPCPL 569

Query: 300 KLPPNIVLK---SSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGL 356
           + PP+ +      + SS  + P    +    A+P   GL S  L        +A   L L
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQ--APPALASPPLQGLPSPPLSPLATPPPQAPPXLAL 627

Query: 357 PQDQDEPGLHLSKPTSSIRPKETRAQ-----HLSPAPGLAQPAAPAQASAAIPAAGKALA 411
           P  Q  P    S P S +     +A      HL  AP    P+ P QA  + PA+     
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687

Query: 412 QAPAPAPGP---AQGPL--PMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTL 466
            A  P+  P   A  PL  P   PA   ++ S + P   P    A     PP P +   +
Sbjct: 688 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM 747

Query: 467 QESNTP 472
             S TP
Sbjct: 748 SPSATP 753



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 97/405 (23%), Positives = 135/405 (33%), Gaps = 47/405 (11%)

Query: 74  SEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYS 133
           S P TTP      P   P P   P   +T    TP   T SS + PP      L S    
Sbjct: 550 SAPLTTPH-LETPPCPAPCPLQAPPSPLT----TPPPETPSSIATPPPQAPPALASPPLQ 604

Query: 134 -LPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAP-ASPQEAAL 191
            LP               +  ++  P  P  LA  P +   S  + P  +P A+P   A 
Sbjct: 605 GLPS-----------PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653

Query: 192 D-LDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSS--SQEREQTPSEAMS 248
           + L V L+  P +   + P Q   +     P     TP    P S  +   +  PS   S
Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713

Query: 249 QKAKETVSTRYTQPQP---PPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNI 305
                + +     P P   PP  +P +  A   P+S    P  R+ PL    P ++PP+ 
Sbjct: 714 PPMSPSATPPPQAPPPLAAPPLQVPPSPPASP-PMSPSATPPPRVPPLLAAPPLQVPPSP 772

Query: 306 VLKSSRSSFHSDPQHWLSRHTEAAPGDSGLIS--CSLQEQRKARKEA---LEKLGLPQDQ 360
                 S     P    +    A P    L S   S   Q      A   +  L  P  Q
Sbjct: 773 PASLPMSPLAKPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830

Query: 361 DEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGP 420
             P L  + P   + P    +      P L  P  P         +G  L  A AP P P
Sbjct: 831 APPVL--AAPLLQVPPSPPAS------PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882

Query: 421 AQGPLPMKSPAPGNVAASKSMPISIPK-------APRANSALTPP 458
                P  + +  ++A   S   S P+        P   +A +PP
Sbjct: 883 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 927



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 109/450 (24%), Positives = 149/450 (33%), Gaps = 79/450 (17%)

Query: 76  PATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGL-GLRSGSYSL 134
           PA+      A P++ P  R GP         TPR     S    P+P+GL  LR    + 
Sbjct: 237 PASRSLSSSATPLSSPA-RSGPSAR-----GTPRAPAHPSQ---PKPKGLQALRPPQVTP 287

Query: 135 PRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLD 194
           PR    A +     S+  A+    G   R  P P+    + +  P   P SP  A     
Sbjct: 288 PRK-DAAPALGPLSSSPLATPSPSGTKARPVPPPDN---AATPLPATLPPSPPLAT---P 340

Query: 195 VVLIPP-PEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQERE--QTPSEAMSQKA 251
           + L PP P A    Q      A+ P        TP +  P S Q     Q P    S   
Sbjct: 341 LPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSL 400

Query: 252 KETVSTRYTQPQPPPAGLPQNARAEDAPLSSGE----------DPNSRLAPLTTP-KPRK 300
                      Q PP+ L  ++      L S             P    A LT+P +P  
Sbjct: 401 -----------QAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS 449

Query: 301 LPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEA----LEKLGL 356
            PP+     +  S  + P    S     +P  S L    LQ        +    L  L +
Sbjct: 450 TPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIM 509

Query: 357 PQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAP 416
           P  + +  L  + P+    P       L   P LA P  P Q ++A P     L   P P
Sbjct: 510 PPLETQSSL--APPSLQTPPASLTTPPLENLPSLAPP--PLQTASA-PLTTPHLETPPCP 564

Query: 417 APGPAQGP-LPMKSPAPGNVAASKSMPISIPKA---------------------PRANSA 454
           AP P Q P  P+ +P P   ++  + P   P A                     P+A   
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624

Query: 455 LT------PPKPESGLTLQESNTPGLRQMN 478
           L       PP P +   L    TP  +  N
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPN 654



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 91/412 (22%), Positives = 142/412 (34%), Gaps = 76/412 (18%)

Query: 82  GFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLP-RNIHI 140
           G     I +  PR GP  +     R P +   +S      P       G  S P R    
Sbjct: 64  GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123

Query: 141 ARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVS-----QSSQPRQAPASPQEA----AL 191
            R     +   + S+      G+    P++  +S      +S P     SP  A    A 
Sbjct: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183

Query: 192 DLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHT---PSSSQEREQTPSEAMS 248
             +V L  P  + R   P         EGP +   +   H+   PS +  R  +    + 
Sbjct: 184 GTEVGLPRPAPSARPRPP--------TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235

Query: 249 QKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKL----PPN 304
           + A  ++S+  T         P ++ A   P + G  P +   P + PKP+ L    PP 
Sbjct: 236 RPASRSLSSSAT---------PLSSPARSGPSARG-TPRAPAHP-SQPKPKGLQALRPPQ 284

Query: 305 IVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPG 364
           +      ++    P   LS    A P  SG          KAR                 
Sbjct: 285 VTPPRKDAAPALGP---LSSSPLATPSPSG---------TKARP---------------- 316

Query: 365 LHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPG---PA 421
             +  P ++  P       L P+P LA P   A  S + P + + L   PA  P    P+
Sbjct: 317 --VPPPDNAATPLPAT---LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371

Query: 422 QGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPG 473
               PM++P     +     PI +P +  + S   PP P +  +LQ + + G
Sbjct: 372 MTTPPMQAPP----SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 85/350 (24%), Positives = 122/350 (34%), Gaps = 39/350 (11%)

Query: 207 TQPEQCREASLPEGPGQQG-HTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPP 265
           + P +    + P   GQ+G       T +  +  E     A+S  A+   S        P
Sbjct: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG-------P 167

Query: 266 PAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRH 325
             G P  A A  +  +  E    R AP   P+P    P   + S+     ++P     R 
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227

Query: 326 TEAAPG----DSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRA 381
             A  G     S  +S S        +      G P+    P     K   ++RP +   
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287

Query: 382 QHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSM 441
                AP L  P + +  +   P+  KA    P P P  A  PLP   P    +A    +
Sbjct: 288 PRKDAAPALG-PLSSSPLATPSPSGTKA---RPVPPPDNAATPLPATLPPSPPLATPLPL 343

Query: 442 PISIPKAPRANSAL-----TPPK--PESGLTLQESNTPGLRQM-------NFKSNTLER- 486
               P AP +   L     TPP   P S  T      P L+ +       +  S +L+  
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403

Query: 487 -SGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLR---NSRPRPAS 532
            S + LSS  +T    SP   T     SFL  +SP   +    S  RPAS
Sbjct: 404 PSPLALSSLQATTSLGSP---TLQATHSFL-TMSPRQTQASLTSPSRPAS 449



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 86/381 (22%), Positives = 133/381 (34%), Gaps = 52/381 (13%)

Query: 65   ADSGLSTDESEPATTPRGFRALPI-TQPTPRGGP--EETITQQGRTPRTVTESSSSHPPE 121
            A   +S   + P+  P    A P+   P+P   P    + T   + P  +       PP 
Sbjct: 681  ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740

Query: 122  PQGLGLRSGSYSLPRNI---------HIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQ 172
            P      S S + P  +          +  S       +  +   P  P  LA  P +  
Sbjct: 741  PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800

Query: 173  VSQ-SSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLH 231
             S  +S P QAP SP  A+L +  +  PPP+A           A L + P     +P L 
Sbjct: 801  PSPPASFPGQAPFSPS-ASLPMSPLATPPPQA------PPVLAAPLLQVPPSPPASPTLQ 853

Query: 232  TPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLA 291
             P     R  TP    S             P PPP+      R+  + LS  +      +
Sbjct: 854  AP----RRPPTPGPDTSVSGPRLTLALAPGPPPPPS------RSPSSTLSGPDLAGHSSS 903

Query: 292  PLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEAL 351
              +TP+  +             + S P+   +    + P D+ L +C      +     L
Sbjct: 904  ATSTPEELR------------GYDSGPEGGAAA---SPPPDAELAACHPAAWSRGPAPPL 948

Query: 352  EKLGLPQDQDEPGLHLSKPTSS---IRPKETRA-QHLSPAPGLAQPAAPAQASAAIPAAG 407
               G P     P    + P S+       ET   +  +PAPG   P  P+  ++   AA 
Sbjct: 949  AFRGAP-GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP-GPSPGTSGGKAAA 1006

Query: 408  KALAQAPAPAPGPAQ-GPLPM 427
             A A A + +P  A+ G LP+
Sbjct: 1007 GAGAGASSRSPKQARLGELPL 1027


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 72.8 bits (177), Expect = 9e-13
 Identities = 93/387 (24%), Positives = 139/387 (35%), Gaps = 59/387 (15%)

Query: 166 PEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQG 225
           PE  K Q   + +P Q P    +     D   +P     RD    Q ++A +  G   + 
Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQT----DHAKLPLQ---RDASRPQTKQADIVRGESVK- 295

Query: 226 HTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGED 285
             P L +PS    ++ TP +                   PPA  P + +++  P      
Sbjct: 296 --PSLPSPSKPPIQQPTPGK-------------------PPAQQPGHEKSQPGPAKPPAQ 334

Query: 286 PNSRLAPLT----TPKPRKLPPNIVLKSSRSSFHSDP---QHWLSRHTEAAPGDSGL--- 335
           P+    PL     T KP   PP      ++    + P   Q    + +   PG   L   
Sbjct: 335 PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP 394

Query: 336 --ISCSLQEQRKARKEALEKLGLPQD-QDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQ 392
             +  +  +Q    K   +++G P+    +PGL    P  +  P +T  Q   P    AQ
Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ--SPAKAPGPTKTPVQQPGPGKIPAQ 452

Query: 393 PAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSP--APGNVAASKSMPISIPKAPR 450
            A P + SA      K  +Q P PA  P Q P P K P   PG+       P S    P+
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512

Query: 451 ANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLG 510
                 P   + G T   S  PG    + K +  + S    S+  ST+    P + T  G
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPG----SAKPSAQQPSPAKPSAQQSTK----PVSQTGSG 564

Query: 511 KGSFLDKISPSVLRNSRPRPASLGTGK 537
           K      + P  +  S  +P S G  K
Sbjct: 565 K-----PLQPPTVSPSAKQPPSQGLPK 586



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 113/480 (23%), Positives = 159/480 (33%), Gaps = 74/480 (15%)

Query: 80  PRGFRALPITQPTPRGGPEETITQQGRTPRTVTE----SSSSHPPEPQGLGLRS-GSYSL 134
           P G    P  QP    GP +  TQQ  TP+ + +     S +  P P    ++  G   +
Sbjct: 394 PPGVGKTPAQQP----GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 135 PRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLD 194
           P       +Q      T A    P +P    P P K    Q    +  P  P  A     
Sbjct: 450 P-------AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK---- 498

Query: 195 VVLIPPPEAFRDTQPEQCREASLPEGPGQQGHT-PQLHTPSSSQEREQTPSEA---MSQK 250
               PP +    T+P   +       P Q G T P    P S++   Q PS A     Q 
Sbjct: 499 ----PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554

Query: 251 AKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLK-- 308
            K    T   +P  PP   P   +     L     P      L    P K   N   +  
Sbjct: 555 TKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQ 614

Query: 309 ---SSRSSFHSDP-----QHWLSRHTE---AAPGDSGLISCSLQEQRKARKEALEKLGLP 357
               S   F+ +P     + WL  + +   A  GD   +  S Q + K            
Sbjct: 615 TTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTS---A 671

Query: 358 QDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPA 417
             +  P    + P     PK    Q LS AP   +P  P      +  +  A A+ P P 
Sbjct: 672 VSKSSPQPQQTSPKKDAAPK----QDLSKAPEPKKP-PPLVKQPTLHGSPSAKAKQP-PE 725

Query: 418 PGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPP---KPESGLTLQESNT--P 472
                 P P K P         S+P    KAP A+     P   KP + L    S T  P
Sbjct: 726 ADSLSKPAPPKEP---------SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776

Query: 473 GLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPAS 532
            +     +S   E++   L +  +    + P T          +K+SP   + + PRPAS
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTG---------EKVSPFDSK-AIPRPAS 826



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 96/423 (22%), Positives = 162/423 (38%), Gaps = 71/423 (16%)

Query: 149  STTQASSHNPGEPGRLAPEPE---KEQVSQSSQPRQAPASPQEAAL--DLDVVLIPPPEA 203
            +TT A S +  +P + +P+ +   K+ +S++ +P++ P   ++  L          PPEA
Sbjct: 667  TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726

Query: 204  FRDTQPEQCREASLP-------------EGPGQQGHTPQLHTPSSSQEREQTPSEAMSQK 250
               ++P   +E S+P             + P     T  L + SS+  +   PS  +  +
Sbjct: 727  DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786

Query: 251  AKE-------TVSTRYTQPQPPPAGL--PQNARAEDAPLSS-------GEDPNSRLAPLT 294
            A+E       T S + +Q  PP      P +++A   P S        G    S+     
Sbjct: 787  AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV 846

Query: 295  TPKPRKLPPNIVLKSSRSSFHSDPQHW-LSRHTEAAPGDSGLISCSLQEQRKARKEALEK 353
             P  +K  P    K +++     P    + + +   PG       ++   +++ K     
Sbjct: 847  DPVQKKEEP----KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPK----- 897

Query: 354  LGLPQDQDEP-GLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAP-AQASAAIPAAGKALA 411
               PQ+Q     L+L   T + + + T  Q           A+  +QAS  I  AG+   
Sbjct: 898  ---PQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQ--- 951

Query: 412  QAPAPAPGPAQGP-LPMK-SPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQES 469
                P P    GP  PMK +PAP     S+  P S  +AP A +   P K E+     E 
Sbjct: 952  ----PGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007

Query: 470  NTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPR 529
              P   Q    + T++R+         TEK   P   +          + P+ L  S P+
Sbjct: 1008 LEPKAEQ----APTVKRT--------ETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS-PK 1054

Query: 530  PAS 532
            P S
Sbjct: 1055 PES 1057



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 94/446 (21%), Positives = 153/446 (34%), Gaps = 57/446 (12%)

Query: 64  EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQ 123
           +A  G ++ +    T P      P   P  + GP +   QQ  + +  ++   S  P PQ
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512

Query: 124 GLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPG--EPGRLAPEPEKEQVSQSSQP-- 179
             G    S   P              +T+  S  PG  +P    P P K    QS++P  
Sbjct: 513 QPGPAKPSPQQP-------------GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559

Query: 180 RQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASL----PEGPGQQGHTPQLHT--- 232
           +     P +          PP +    T    C    L    PE       T    T   
Sbjct: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619

Query: 233 -------PSSSQEREQTPSEAMSQKA-KETVSTRYTQPQPPPAGLP---QNARAEDAPLS 281
                  P  ++ +E        ++A    ++   + PQP     P    +A ++ +P  
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP 679

Query: 282 SGEDPNSRLAP----LTTPKPRKLPPNI---VLKSSRSSFHSDPQHWLSRHTEAAPGDSG 334
               P    AP       P+P+K PP +    L  S S+    P    S    A P +  
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPS 739

Query: 335 LISCSLQEQRKA----RKEALEKLGLP-QDQDEPGLHLSKPTSSIRPKETRAQHLSPAPG 389
           + S    EQ KA     K    K+  P  D        +KP       +++A+  +  P 
Sbjct: 740 VPS----EQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795

Query: 390 LAQPAAPAQASAAIPAAGKALAQAPAPA-PGPAQGPLPMKSPAPGNVAASKSM--PISIP 446
               A P+Q   + P  G+ ++   + A P PA     +  P P + +  +    P+   
Sbjct: 796 KTDSAKPSQ---SFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKK 852

Query: 447 KAPRANSALTPPKPESGLTLQESNTP 472
           + P+       PKP++    + S TP
Sbjct: 853 EEPKKAQTKMSPKPDAKPMPKGSPTP 878



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 53/232 (22%), Positives = 86/232 (37%), Gaps = 27/232 (11%)

Query: 89  TQPTPRGGPEETITQQGRTPRTVTES---SSSHPPEPQGLGLRSGSYSLPRNIHIARSQN 145
           T+P       ++  ++  TP   T+S   S S PP  + +     S ++PR    ++  +
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS-PFDSKAIPRPASDSKIIS 832

Query: 146 FRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQP--------RQAPASPQEAALDLDVVL 197
               ++++      +P +   EP+K Q   S +P           P  P+  A       
Sbjct: 833 HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ----T 888

Query: 198 IPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTP-SEAMSQKAKETVS 256
           +P P+     Q EQ R  SL  G        Q  TP  +   +      ++  +A   +S
Sbjct: 889 VPTPQQSPKPQ-EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947

Query: 257 TRYTQPQP-----PPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPP 303
           T   QP P     P A + Q       P S G   ++  AP   P P K  P
Sbjct: 948 TA-GQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP---PAPAKSIP 995


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 72.8 bits (177), Expect = 9e-13
 Identities = 93/387 (24%), Positives = 139/387 (35%), Gaps = 59/387 (15%)

Query: 166 PEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQG 225
           PE  K Q   + +P Q P    +     D   +P     RD    Q ++A +  G   + 
Sbjct: 244 PEKIKSQPPGTGKPIQGPTQTPQT----DHAKLPLQ---RDASRPQTKQADIVRGESVK- 295

Query: 226 HTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGED 285
             P L +PS    ++ TP +                   PPA  P + +++  P      
Sbjct: 296 --PSLPSPSKPPIQQPTPGK-------------------PPAQQPGHEKSQPGPAKPPAQ 334

Query: 286 PNSRLAPLT----TPKPRKLPPNIVLKSSRSSFHSDP---QHWLSRHTEAAPGDSGL--- 335
           P+    PL     T KP   PP      ++    + P   Q    + +   PG   L   
Sbjct: 335 PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP 394

Query: 336 --ISCSLQEQRKARKEALEKLGLPQD-QDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQ 392
             +  +  +Q    K   +++G P+    +PGL    P  +  P +T  Q   P    AQ
Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ--SPAKAPGPTKTPVQQPGPGKIPAQ 452

Query: 393 PAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSP--APGNVAASKSMPISIPKAPR 450
            A P + SA      K  +Q P PA  P Q P P K P   PG+       P S    P+
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512

Query: 451 ANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLG 510
                 P   + G T   S  PG    + K +  + S    S+  ST+    P + T  G
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPG----SAKPSAQQPSPAKPSAQQSTK----PVSQTGSG 564

Query: 511 KGSFLDKISPSVLRNSRPRPASLGTGK 537
           K      + P  +  S  +P S G  K
Sbjct: 565 K-----PLQPPTVSPSAKQPPSQGLPK 586



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 113/480 (23%), Positives = 159/480 (33%), Gaps = 74/480 (15%)

Query: 80  PRGFRALPITQPTPRGGPEETITQQGRTPRTVTE----SSSSHPPEPQGLGLRS-GSYSL 134
           P G    P  QP    GP +  TQQ  TP+ + +     S +  P P    ++  G   +
Sbjct: 394 PPGVGKTPAQQP----GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449

Query: 135 PRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLD 194
           P       +Q      T A    P +P    P P K    Q    +  P  P  A     
Sbjct: 450 P-------AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK---- 498

Query: 195 VVLIPPPEAFRDTQPEQCREASLPEGPGQQGHT-PQLHTPSSSQEREQTPSEA---MSQK 250
               PP +    T+P   +       P Q G T P    P S++   Q PS A     Q 
Sbjct: 499 ----PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554

Query: 251 AKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLK-- 308
            K    T   +P  PP   P   +     L     P      L    P K   N   +  
Sbjct: 555 TKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQ 614

Query: 309 ---SSRSSFHSDP-----QHWLSRHTE---AAPGDSGLISCSLQEQRKARKEALEKLGLP 357
               S   F+ +P     + WL  + +   A  GD   +  S Q + K            
Sbjct: 615 TTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTS---A 671

Query: 358 QDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPA 417
             +  P    + P     PK    Q LS AP   +P  P      +  +  A A+ P P 
Sbjct: 672 VSKSSPQPQQTSPKKDAAPK----QDLSKAPEPKKP-PPLVKQPTLHGSPSAKAKQP-PE 725

Query: 418 PGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPP---KPESGLTLQESNT--P 472
                 P P K P         S+P    KAP A+     P   KP + L    S T  P
Sbjct: 726 ADSLSKPAPPKEP---------SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776

Query: 473 GLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPAS 532
            +     +S   E++   L +  +    + P T          +K+SP   + + PRPAS
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTG---------EKVSPFDSK-AIPRPAS 826



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 96/423 (22%), Positives = 162/423 (38%), Gaps = 71/423 (16%)

Query: 149  STTQASSHNPGEPGRLAPEPE---KEQVSQSSQPRQAPASPQEAAL--DLDVVLIPPPEA 203
            +TT A S +  +P + +P+ +   K+ +S++ +P++ P   ++  L          PPEA
Sbjct: 667  TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726

Query: 204  FRDTQPEQCREASLP-------------EGPGQQGHTPQLHTPSSSQEREQTPSEAMSQK 250
               ++P   +E S+P             + P     T  L + SS+  +   PS  +  +
Sbjct: 727  DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786

Query: 251  AKE-------TVSTRYTQPQPPPAGL--PQNARAEDAPLSS-------GEDPNSRLAPLT 294
            A+E       T S + +Q  PP      P +++A   P S        G    S+     
Sbjct: 787  AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV 846

Query: 295  TPKPRKLPPNIVLKSSRSSFHSDPQHW-LSRHTEAAPGDSGLISCSLQEQRKARKEALEK 353
             P  +K  P    K +++     P    + + +   PG       ++   +++ K     
Sbjct: 847  DPVQKKEEP----KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPK----- 897

Query: 354  LGLPQDQDEP-GLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAP-AQASAAIPAAGKALA 411
               PQ+Q     L+L   T + + + T  Q           A+  +QAS  I  AG+   
Sbjct: 898  ---PQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQ--- 951

Query: 412  QAPAPAPGPAQGP-LPMK-SPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQES 469
                P P    GP  PMK +PAP     S+  P S  +AP A +   P K E+     E 
Sbjct: 952  ----PGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007

Query: 470  NTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPR 529
              P   Q    + T++R+         TEK   P   +          + P+ L  S P+
Sbjct: 1008 LEPKAEQ----APTVKRT--------ETEKKPPPIKDSKSLTAEPQKAVLPTKLEKS-PK 1054

Query: 530  PAS 532
            P S
Sbjct: 1055 PES 1057



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 94/446 (21%), Positives = 153/446 (34%), Gaps = 57/446 (12%)

Query: 64  EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQ 123
           +A  G ++ +    T P      P   P  + GP +   QQ  + +  ++   S  P PQ
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512

Query: 124 GLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPG--EPGRLAPEPEKEQVSQSSQP-- 179
             G    S   P              +T+  S  PG  +P    P P K    QS++P  
Sbjct: 513 QPGPAKPSPQQP-------------GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559

Query: 180 RQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASL----PEGPGQQGHTPQLHT--- 232
           +     P +          PP +    T    C    L    PE       T    T   
Sbjct: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619

Query: 233 -------PSSSQEREQTPSEAMSQKA-KETVSTRYTQPQPPPAGLP---QNARAEDAPLS 281
                  P  ++ +E        ++A    ++   + PQP     P    +A ++ +P  
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP 679

Query: 282 SGEDPNSRLAP----LTTPKPRKLPPNI---VLKSSRSSFHSDPQHWLSRHTEAAPGDSG 334
               P    AP       P+P+K PP +    L  S S+    P    S    A P +  
Sbjct: 680 QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPS 739

Query: 335 LISCSLQEQRKA----RKEALEKLGLP-QDQDEPGLHLSKPTSSIRPKETRAQHLSPAPG 389
           + S    EQ KA     K    K+  P  D        +KP       +++A+  +  P 
Sbjct: 740 VPS----EQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795

Query: 390 LAQPAAPAQASAAIPAAGKALAQAPAPA-PGPAQGPLPMKSPAPGNVAASKSM--PISIP 446
               A P+Q   + P  G+ ++   + A P PA     +  P P + +  +    P+   
Sbjct: 796 KTDSAKPSQ---SFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKK 852

Query: 447 KAPRANSALTPPKPESGLTLQESNTP 472
           + P+       PKP++    + S TP
Sbjct: 853 EEPKKAQTKMSPKPDAKPMPKGSPTP 878



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 53/232 (22%), Positives = 86/232 (37%), Gaps = 27/232 (11%)

Query: 89  TQPTPRGGPEETITQQGRTPRTVTES---SSSHPPEPQGLGLRSGSYSLPRNIHIARSQN 145
           T+P       ++  ++  TP   T+S   S S PP  + +     S ++PR    ++  +
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS-PFDSKAIPRPASDSKIIS 832

Query: 146 FRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQP--------RQAPASPQEAALDLDVVL 197
               ++++      +P +   EP+K Q   S +P           P  P+  A       
Sbjct: 833 HPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ----T 888

Query: 198 IPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTP-SEAMSQKAKETVS 256
           +P P+     Q EQ R  SL  G        Q  TP  +   +      ++  +A   +S
Sbjct: 889 VPTPQQSPKPQ-EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947

Query: 257 TRYTQPQP-----PPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPP 303
           T   QP P     P A + Q       P S G   ++  AP   P P K  P
Sbjct: 948 TA-GQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP---PAPAKSIP 995


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 127/541 (23%), Positives = 190/541 (35%), Gaps = 86/541 (15%)

Query: 59   GSLDTEADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSH 118
            GS  T    G  T  +    +P+G   LP T P+ +GGP    +++G TP   T S    
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG 1381

Query: 119  P----PEPQ---GLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEP--- 168
            P    P P+    +    G  + P  I ++  +      T+  +  P + G L P     
Sbjct: 1382 PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK-GDLTPPAVTP 1440

Query: 169  -EKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEG----PGQ 223
               ++   +S P+  PA+P     D  +  + PP       P+Q   +S P+     P  
Sbjct: 1441 VSLKKAPATSAPKGGPATPSSKG-DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499

Query: 224  QGHTPQLHT--PSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLS 281
             G  P L    PSS +E   TPS      A            P    L +   A  AP  
Sbjct: 1500 MG-APTLPAVIPSSPKEVPATPSSRRDPIA------------PTATLLSKKTPATLAPKE 1546

Query: 282  SGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQ 341
            +   P      +T P P+K P     K +       P    S+   + P     ++ S  
Sbjct: 1547 ALIPP-----AMTVPSPKKTPAIPTPKEA-------PATPSSKEASSPPA----VTPSTY 1590

Query: 342  EQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASA 401
            +   + KE L    +P     P    +    ++ P        SP  G A PA P     
Sbjct: 1591 KGAPSPKELL----IPPAVTSPSPKEAPTPPAVTPP-------SPEKGPATPA-PKGTPT 1638

Query: 402  AIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRA-NSALTPPKP 460
            + P    +L  +P     PA     M +  P    ASK +P    K P A    L  P P
Sbjct: 1639 SPPVTPSSLKDSPT---SPASVTCKMGATVP---QASKGLPAK--KGPTALKEVLVAPAP 1690

Query: 461  ESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISP 520
            ES        TP +     K    ++S        +T     P  S   G    L  ++P
Sbjct: 1691 ES--------TPIITAPTRKGPQTKKSS-------ATSPPICPDPSAKNGSKGPLSTVAP 1735

Query: 521  SVLRNSRPRPASLGTGKDFAGIQVGKLADLEQEQSSKRLSYQGQSRDKLPRPPCVSVKIS 580
            + L   +   +    GKD +    G LA  E + S+   +        LP+P   SV  +
Sbjct: 1736 APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTA--AAFEKVLPKPESASVSAA 1793

Query: 581  P 581
            P
Sbjct: 1794 P 1794



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 98/439 (22%), Positives = 153/439 (34%), Gaps = 66/439 (15%)

Query: 72   DESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGS 131
            D + PA TP   +  P T   P+GGP    ++   T   VT  S   PP P+ +   S  
Sbjct: 1432 DLTPPAVTPVSLKKAPATS-APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490

Query: 132  Y-------------------SLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPE----- 167
                                S P+ +    S         A+  +   P  LAP+     
Sbjct: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550

Query: 168  -----PEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPG 222
                 P  ++      P++APA+P          + P       +  E     ++     
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSP 1610

Query: 223  QQGHTPQLHTPSSSQEREQTPS-EAMSQKAKETVSTRYTQPQPPP-------AGLPQNAR 274
            ++  TP   TP S ++   TP+ +        T S+    P  P        A +PQ ++
Sbjct: 1611 KEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASK 1670

Query: 275  ---AEDAPLSSGE---DPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEA 328
               A+  P +  E    P     P+ T   RK P     ++ +SS  S P   +     A
Sbjct: 1671 GLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP-----QTKKSSATSPP---ICPDPSA 1722

Query: 329  APGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAP 388
              G  G +S          ++   K    +D          P   + P E++A     A 
Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASH------SPKGPLAPPESKASTPLTAA 1776

Query: 389  G----LAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPIS 444
                 L +P + + ++A  P     LA +P P   P Q  LP    +PG V  S S P++
Sbjct: 1777 AFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLP---SSPGLVLESPSKPLA 1833

Query: 445  IPKAPRANSALTPPKPESG 463
             P        L PP+P SG
Sbjct: 1834 -PADEDELLPLIPPEPISG 1851



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 122/514 (23%), Positives = 176/514 (34%), Gaps = 65/514 (12%)

Query: 1    MPERELWPAGT--GSEPVTRVGSCDSMMS-STSTRSGSSDSSYDFLSTEEKECLLFLEET 57
            +P   L PAGT  G++ V  +    ++   ++S +   ++ S    +   K  L +L ++
Sbjct: 734  VPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADS 793

Query: 58   IGSLDTEADSGLSTDESEPAT----TPRGFRALPITQPTPRGGPEETITQQGRTPRTVTE 113
               L            ++  +    TP G  + P++       PE +++ QG      T 
Sbjct: 794  PSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT 853

Query: 114  SSSSHPPEPQGLGLRSGSYSL-PRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQ 172
             S + PP P+G    S    L P+ + +   +    S         G P   AP+     
Sbjct: 854  HSPT-PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG-PATPAPKQAPAL 911

Query: 173  VSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPG----QQGHTP 228
               SS P++A A+P    +       P P+      P      S   GP     +   TP
Sbjct: 912  SMTSSSPKKARATPAPKGIPAS----PSPKGA--PTPPAATPPSPKGGPATPSPKWAPTP 965

Query: 229  QLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNS 288
               TP S +    TPS        +   T      P P G P     + AP      P S
Sbjct: 966  PAATPPSPKGGPATPSP-------KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018

Query: 289  -RLAPLTTPKPR--KLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDS---GLISCSLQ- 341
             + +P  TP P+    PP     S + S  + P    +  T AA   S   G  + SL+ 
Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078

Query: 342  ---------EQRKARKEALEKLGLPQDQ----DEPGLHLSKPTSSIRPKETRAQHLSPAP 388
                        K         G P         P   L+ P     P    A   SP  
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138

Query: 389  GLAQP---AAPAQASAAIPAAGKALAQ--------APAPAPGPAQGPLPMKSP--APGNV 435
            GLA P    AP   +A  P+    LA          PA  P   +G L   SP  AP   
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198

Query: 436  AASKSMP-----ISIPKAPRANSALTPPKPESGL 464
            AA+   P        PK      A TPP P+ GL
Sbjct: 1199 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1232



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 97/418 (23%), Positives = 136/418 (32%), Gaps = 59/418 (14%)

Query: 79   TPRGFRALPI-TQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRN 137
            +P+G    P  T P+P+GGP     +   TP   T      PP P+G          P  
Sbjct: 935  SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT------PPSPKGGPATPSPKGAP-- 986

Query: 138  IHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVL 197
                        T  A++    + G   P P+      +  P     SP  AA       
Sbjct: 987  ------------TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP--AATPFPKGA 1032

Query: 198  IPPPEAFRDTQPEQCREASLPEG----PGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKE 253
              PP A   +         LP+G    P     +P+    + S +   TP  A     K 
Sbjct: 1033 STPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092

Query: 254  TVSTRYTQPQP-PPAGLPQNARA-------EDAPLSSGEDPNSRLAPLTTPKPRKLP--P 303
              +T   +  P PPA  P + +        + AP +    P S    L TP P+  P  P
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1152

Query: 304  NIVLKSSRSSFHSDPQHWLSRHTEAAPGD--SGLISCSLQ--EQRKARKEALEKLGLPQD 359
                 S +    + P         A P     GL + S +      A      K GL   
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212

Query: 360  QDE------------PGLHLSKPTSSIRPKETRAQHLSPAPGLAQP---AAPAQASAAIP 404
              +            P   L+ P+    P    A   SP  G A P    AP   +A  P
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272

Query: 405  AAGKALAQAP---APAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPK 459
            +    LA  P   AP P     P P   PA      + + P + P +P+ +    PPK
Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 82/324 (25%), Positives = 115/324 (35%), Gaps = 36/324 (11%)

Query: 153 ASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQC 212
           A  ++P + G L   P    V  +S+      SPQ     L   L+  PE  +       
Sbjct: 684 APKNHPVKEGTLTTLP---LVPTASENCPVAPSPQNTCAPL-ATLVLAPEIPKSVPSPSL 739

Query: 213 REASLPEGPGQQ---GHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGL 269
             A  P G  +     HT  L   +SS +   T     S  A    +  Y    P P G+
Sbjct: 740 PPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGV 799

Query: 270 ---PQNARAEDAPLSSGED-PNSRL-APLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSR 324
              PQ  R      S+G D P   L +P++  +   LP N +      SF        + 
Sbjct: 800 SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSL------SFQGSKDSPATT 853

Query: 325 HTEAAPGDSGLISCSLQEQRKARKEAL--------EKLGLPQDQDEPGLHLSK--PTSSI 374
           H+   P   G  + S       +   L          + LP  ++ P     K  P  S+
Sbjct: 854 HSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSM 913

Query: 375 RPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGN 434
                +    +PAP    PA+P+   A  P A    A  P+P  GPA  P P  +P P  
Sbjct: 914 TSSSPKKARATPAP-KGIPASPSPKGAPTPPA----ATPPSPKGGPAT-PSPKWAPTP-- 965

Query: 435 VAASKSMPISIPKAPRANSALTPP 458
            AA+   P   P  P    A TPP
Sbjct: 966 PAATPPSPKGGPATPSPKGAPTPP 989



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 106/453 (23%), Positives = 146/453 (32%), Gaps = 78/453 (17%)

Query: 59   GSLDTEADSGLSTDESEPATTPRGFRALP----------ITQPTPRGGPEETITQQGRTP 108
            G L T    G  T  +    +P+G  A P           T P+P+GG           P
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP------PP 1168

Query: 109  RTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEP 168
            +    + ++ PP P+G GL + S   P+             TT A++    + G   P P
Sbjct: 1169 KGAPTTPAATPPSPKG-GLATPS---PKGA----------PTTPAATPPSPKGGLATPSP 1214

Query: 169  EKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTP 228
            +       + P   P SP+           P   A     P+       P+G      TP
Sbjct: 1215 K----GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG----APTP 1266

Query: 229  QLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNS 288
               TP S +    TP        K   +     P P P G P  +  + AP      P S
Sbjct: 1267 PAATPPSLKGGLATPPH------KGAPNPAVVTP-PSPKGGPATSPPKGAPTPPAATPPS 1319

Query: 289  RLAPLTTPKPR--KLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKA 346
                  TP P+    PP +   S + +        L   T ++ G     S S +     
Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGT------PTLPATTPSSKGGPTTPS-SKEGPTPP 1372

Query: 347  RKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQP------AAPAQAS 400
                  K G       P    + P+    P       LSP    A P      A P++  
Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432

Query: 401  AAIPAAGK-ALAQAP---APAPGPA-------------QGPLPMKSPAPGNVAASKSMPI 443
               PA    +L +AP   AP  GPA               P P + PAP  VA S S P 
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS-PK 1491

Query: 444  SIPKAPRANSALTPPKPESGLTLQESNTPGLRQ 476
              P  P    A T P        +   TP  R+
Sbjct: 1492 KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 134/599 (22%), Positives = 206/599 (34%), Gaps = 87/599 (14%)

Query: 8    PAGTGSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEE----TIGSLDT 63
            P  T +E  +   + D     TST    S+ S    S    + LL   E    +   LDT
Sbjct: 718  PVTTSTEASSSPTTADGASMPTST---PSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDT 774

Query: 64   EADSGLSTDESEPATTPRGFRALPITQP--------------TPRGGPE----ETITQQG 105
                  ST+ S   TT  G  ++PI+ P              TP   PE     T     
Sbjct: 775  STHITTSTEASCSPTTTEG-TSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDS 833

Query: 106  RTPRTVTESSSSHPPEPQGLGLRSGSYSLPR----------------------------- 136
             +P T +   SS P   +G  + + +YS  R                             
Sbjct: 834  NSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTS 893

Query: 137  ----NIHIARSQNFRKSTTQASSHNPGEPGR-LAPEPEKEQVSQSSQPRQAPASPQEAAL 191
                N   ARS       T   +  PGE    L   P+      SS+ R   A+P    +
Sbjct: 894  TPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATP----V 949

Query: 192  DLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSS-----SQEREQTPSEA 246
            D    +    EA   + P      S+P     +G TP   TP S     + E     +  
Sbjct: 950  DTSTPVTTSTEA--TSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTP 1007

Query: 247  MSQKAKETVSTRYTQPQPPPAG--LPQNARAEDA------PLSSGEDPNSRLAPL-TTPK 297
            +      T ST  + P P   G  +P +  +E +      P+S+    +S  + L TTP 
Sbjct: 1008 VDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPA 1067

Query: 298  PRKLPPNIVLKSSRSSFHSDPQHW-LSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGL 356
                P     ++S SS  +D      S ++E   G + L S  +  +     EA      
Sbjct: 1068 DTSTPVTTYSQASSSSTTADGTSMPTSTYSE---GSTPLTSVPVSTRLVVSSEASTLSTT 1124

Query: 357  PQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAP 416
            P D   P    ++ +SS    E  +   SP      P A    S  +  + +A   +  P
Sbjct: 1125 PVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTP 1184

Query: 417  APGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPGLRQ 476
                 Q     ++ +P   A   SMP S P   R+    + P   + +   E++T  L  
Sbjct: 1185 VDSKTQVATSTEASSPPPTAEVTSMPTSTP-GERSTPLTSMPVRHTPVASSEAST--LST 1241

Query: 477  MNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPASLGT 535
                ++T   +    SS  +T +  S  TST+    + L  I  S    + P  ++L T
Sbjct: 1242 SPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLT 1300



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 116/535 (21%), Positives = 201/535 (37%), Gaps = 76/535 (14%)

Query: 6   LWPAGTG--SEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGSLDT 63
           L+P+ T   S P T  G+ D  MS+ S  S SS  +  F+ST            + S + 
Sbjct: 128 LFPSSTEDTSSPTTPEGT-DVPMSTPSEESISSTMA--FVSTAP----------LPSFEA 174

Query: 64  EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQ 123
                   D S P TT     + P T P     P+ T   +G TP T   +S+      +
Sbjct: 175 YTSLTYKVDMSTPLTTSTQASSSPTT-PESTTIPKST-NSEGSTPLTSMPASTMKVASSE 232

Query: 124 GLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR----LAPEPEKEQVSQSSQP 179
            + L +    +   + I+   +   +T +  S +   P      L   P    +  SS+ 
Sbjct: 233 AITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEA 292

Query: 180 RQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQER 239
                +P  AA ++ V  I   EA   + P      S+P     +G TP   TP+S+   
Sbjct: 293 STLSTTP--AATNIPV--ITSTEA--SSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPV 346

Query: 240 EQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAED---APLSSGEDPNSRLAPLTTP 296
             +    +S    +T +   T  +  P+ LP  A A     + LS G  P + + P++T 
Sbjct: 347 ATSEMSTLSITPVDTSTLVTTSTE--PSSLPTTAEATSMLTSTLSEGSTPLTNM-PVST- 402

Query: 297 KPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALE---K 353
                   I++ SS +S            T   P DS     +  E   +   A +    
Sbjct: 403 --------ILVASSEAS-----------TTSTIPVDSKTFVTTASEASSSPTTAEDTSIA 443

Query: 354 LGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQA 413
              P +   P   +   T+ +   E      +P     Q     +AS++ P A   +   
Sbjct: 444 TSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTA--EVNSM 501

Query: 414 PAPAPGPAQGPLPMKSPAPGNVAASKSMPIS---------IPKAPRANSALTPPKPES-- 462
           P   P     PL   S +   VA+S++  +S         +  +  A+S+ T P+  S  
Sbjct: 502 PTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIP 561

Query: 463 GLTLQESNTPGLRQ-------MNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLG 510
             T  E +TP           ++ +++T   +    +++++T  +AS  ++T+ G
Sbjct: 562 TSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEG 616



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 110/557 (19%), Positives = 194/557 (34%), Gaps = 60/557 (10%)

Query: 8    PAGTGSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGSLDTEADS 67
            P  T SE  T + S    +  ++T   +S++S    +  +    +     + S  T A+ 
Sbjct: 1446 PTSTPSEGKTPLKS----IPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE- 1500

Query: 68   GLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGR---TPRTVTESSSSHPPEPQG 124
            G S   S P+       ++P++  T       +++       TP T    +SS P    G
Sbjct: 1501 GTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADG 1560

Query: 125  LGLRSGSY--------SLP-RNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQ 175
              +++ +Y        SLP   + +  S+    STT   S         A      + S 
Sbjct: 1561 TSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSS 1620

Query: 176  SSQPRQAPASPQEAALDLDVVLIPPPEAFR-DTQPEQCREASLPEGPGQQGHTPQLHT-- 232
             +    +  SP   ++ +    +  PEA    T P       +         TP   T  
Sbjct: 1621 MTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSM 1680

Query: 233  PSSSQEREQTPSEAMSQK----AKETVSTRYTQPQPPPAGLPQNARAEDAPLSS------ 282
            P+S+    +TP  +++ +    A   +ST  T P      +  +  A  +P +S      
Sbjct: 1681 PTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMP 1740

Query: 283  GEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEA-------------- 328
               P+    PLT+      P      S+ S+   D    ++  TEA              
Sbjct: 1741 NSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPT 1800

Query: 329  ---APGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKE-TRAQHL 384
               + G + L S  +     A  EA      P D + P +  +  +SS  P E T     
Sbjct: 1801 STLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATS 1860

Query: 385  SPAPG-LAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPI 443
            +P+ G  A  + P   +    +    L+  PA    P      + S      A   SMP 
Sbjct: 1861 TPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSP--TTADGSSMPT 1918

Query: 444  SIPKAPRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASP 503
            S P+  R      PP     ++   + T    ++N  S TL  +   +++Y       + 
Sbjct: 1919 STPREGR------PPLTSIPVS---TTTVASSEINTLSTTLADTRTPVTTYSQASSSPTT 1969

Query: 504  KTSTSLGKGSFLDKISP 520
               TS+   ++ +  +P
Sbjct: 1970 ADGTSMPTPAYSEGSTP 1986



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 114/529 (21%), Positives = 190/529 (35%), Gaps = 53/529 (10%)

Query: 12   GSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGSLDTEADSGLST 71
            GS P T      SM  ST     S  S+      +    +    E   S  T   + + T
Sbjct: 2218 GSTPFT------SMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPT 2271

Query: 72   DESEPATTPRGFRALPITQPTPRGGPEETITQ---QGRTPRTVTESSSSHPPEPQGLGLR 128
                  TTP    ++P++          T++       TP T +  +SS PP  +G  + 
Sbjct: 2272 STLSEGTTP--LTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMP 2329

Query: 129  SGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQE 188
            + S S   N  + R      STT  +S          P      V+  SQ   +P +  +
Sbjct: 2330 T-STSSEGNTPLTR---MPVSTTMVASFETSTLS-TTPADTSTPVTTYSQAGSSPTTADD 2384

Query: 189  AALDLDVV---LIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSE 245
             ++          P       T P    EAS          TP     ++S E   +P+ 
Sbjct: 2385 TSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTP----VTTSTEASSSPTT 2440

Query: 246  AMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNI 305
            A       +  +  T P    A +P        P+ S E       P+ T  P      +
Sbjct: 2441 AEGTSIPTSPPSEGTTPL---ASMP----VSTTPVVSSEAGTLSTTPVDTSTP------M 2487

Query: 306  VLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGL 365
               +  SS  +  +  +   + A+ G + L S  +     A  EA      P D + P +
Sbjct: 2488 TTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVV 2547

Query: 366  HLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAP--APGPAQG 423
              ++ +SS    E  +    P    ++ + P +   ++P + K LA + A   +  P   
Sbjct: 2548 TSTEISSSATSAEGTSM---PTSTYSEGSTPLR---SMPVSTKPLASSEASTLSTTPVDT 2601

Query: 424  PLPM----KSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTPGLRQMNF 479
             +P+    ++ +    A   SMPIS P     +++LT     S + +  S    L     
Sbjct: 2602 SIPVTTSTETSSSPTTAKDTSMPISTPS--EVSTSLTSIL-VSTMPVASSEASTLSTTPV 2658

Query: 480  KSNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDKI--SPSVLRNS 526
             + TL  +  G SS  +T + +S  TST   + + L  I  S ++L NS
Sbjct: 2659 DTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANS 2707



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 118/558 (21%), Positives = 190/558 (34%), Gaps = 91/558 (16%)

Query: 8    PAGTGSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGSLDTEADS 67
            P  T SE +T + S    +  ++T   SS++S   LST   +       T  +  TEA S
Sbjct: 3213 PTSTPSEGMTPLTS----VPVSNTPVASSEAS--ILSTTPVD-----SNTPLTTSTEASS 3261

Query: 68   GLSTDE--SEPATTPRG----FRALPITQPTPRGGPEETITQ---QGRTPRTVTESSSSH 118
               T E  S P +TP        ++P++  T       T++       TP T    +SS 
Sbjct: 3262 SPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSS 3321

Query: 119  PPEPQGLGLRSGSYSLP---------RNIHIARSQNFRKSTTQASSHNP---GEPGRLAP 166
            PP   G  + + +YS               +  S+    STT   +  P        L+P
Sbjct: 3322 PPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSP 3381

Query: 167  EPEKEQVSQSSQPRQA-------PASP-----------QEAALDLDVVLIPPPEAFRDTQ 208
               +     +S P +        P S                +D + ++    EA   + 
Sbjct: 3382 TTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEA--SSS 3439

Query: 209  PEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAG 268
            P      SLP     +G TP    P S+     + +  +S    +T ST  T   P  + 
Sbjct: 3440 PTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDT-STPVTTSSPTNSS 3498

Query: 269  LPQNARAEDAPLSS---GEDPNSRLAPLTTP-----------KPRKLPPNIVLKSSRSSF 314
             P  A     P S+   G  P + +   TTP            P      +   S  SS 
Sbjct: 3499 -PTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSS 3557

Query: 315  HSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSI 374
             +  Q    R +  + G S L +  L        EA        D+  P    ++  S+ 
Sbjct: 3558 PATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTP 3617

Query: 375  RPKETRAQHLSPAPGLAQPAA---PAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPA 431
             P E     +S    ++ P      +  S  I  AG A               LP+ +  
Sbjct: 3618 TPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTA-------------STLPVDTST 3664

Query: 432  PGNVAASKSMPISIPKAPRANS--ALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGV 489
            P     + +   S P  P   +    TP +  + LT    +T   R  + + +TL    V
Sbjct: 3665 P---VITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVST--TRVTSSEGSTLSTPSV 3719

Query: 490  GLSSYLSTEKDASPKTST 507
              S+ ++T  +A   ++T
Sbjct: 3720 VTSTPVTTSTEAISSSAT 3737



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 100/526 (19%), Positives = 174/526 (33%), Gaps = 59/526 (11%)

Query: 9    AGTGSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGSLDTEADSG 68
            A   S P T  G+   + +    R+  +  S   +     E    L  T    DT     
Sbjct: 2963 AEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEAST-LSRT--PADTSTPVT 3019

Query: 69   LSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLR 128
             ST+ S   TT  G   +PI+ P+           +G TP T    S++    P+   L 
Sbjct: 3020 TSTEASSSPTTAEG-TGIPISTPS-----------EGSTPLTSIPVSTTPVAIPEASTL- 3066

Query: 129  SGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQE 188
              +  +  N  +  S     S T A   +               V  S+ P  + A    
Sbjct: 3067 -STTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTL 3125

Query: 189  AALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMS 248
            +   +D            + P      S+P     +G TP  + P S+     +    +S
Sbjct: 3126 STTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLS 3185

Query: 249  QKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLK 308
                +T +   T  +   A     A     P S+   P+  + PLT+      P      
Sbjct: 3186 ATPVDTSTPVTTSTE---ATSSTTAEGTSIPTST---PSEGMTPLTSVPVSNTPVASSEA 3239

Query: 309  SSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLS 368
            S  S+   D    L+  TEA+         S+                P +   P   + 
Sbjct: 3240 SILSTTPVDSNTPLTTSTEASSSPPTAEGTSM------------PTSTPSEGSTPLTSMP 3287

Query: 369  KPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAG------KALAQAPAPAPGPAQ 422
              T+++   ET     +PA         +QAS++ P A          ++   P    + 
Sbjct: 3288 VSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSF 3347

Query: 423  GPLPMKS---------PAPGNVAASKSMPISIPKAPRANSALTPPKPESGLT----LQES 469
               P+ S         P   +   + S   S+       +++    P  G T    +  S
Sbjct: 3348 STTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVS 3407

Query: 470  NTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFL 515
             TP    ++ + NTL  + V  ++ ++T  +AS  +S ++ +G+ L
Sbjct: 3408 TTP---VVSSEVNTLSTTPVDSNTLVTTSTEAS--SSPTIAEGTSL 3448



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 65/331 (19%), Positives = 113/331 (34%), Gaps = 32/331 (9%)

Query: 233 PSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAP 292
           P+S+     TP  +MS       S+  +     P              SS   P     P
Sbjct: 502 PTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIP 561

Query: 293 LTTPKPRKLPPNIVLKSSR----------SSFHSDPQHWLSRHTEAAPGD---------- 332
            +TP     P   +  S+R          S+  +D   +++  +EA+             
Sbjct: 562 TSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPT 621

Query: 333 -------SGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLS 385
                  + + S S+     A  EA      P D + P    ++ TSS    E  +   S
Sbjct: 622 STYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTS 681

Query: 386 PAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISI 445
                + P      +  + A+ +A   +  P           ++ +    A   SMP S 
Sbjct: 682 TYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTST 741

Query: 446 PKAPRANSALTP-PKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPK 504
           P     ++ LT  P  ++ LT  E++T     ++  S  +  S     S  +TE  + P 
Sbjct: 742 PS--EGSTPLTSMPVSKTLLTSSEASTLSTTPLD-TSTHITTSTEASCSPTTTEGTSMPI 798

Query: 505 TSTSLGKGSFLDKISPSVLRNSRPRPASLGT 535
           ++ S G    L  I  S+   + P  ++L T
Sbjct: 799 STPSEG-SPLLTSIPVSITPVTSPEASTLST 828



 Score = 34.3 bits (77), Expect = 0.34
 Identities = 106/566 (18%), Positives = 181/566 (31%), Gaps = 67/566 (11%)

Query: 68   GLSTDESEPATTPRGFRALPITQPTPRGGPEETITQ---QGRTPRTVTESSSSHPPEPQG 124
            G S   S P+       ++P++          T++       TP T +  ++S P   +G
Sbjct: 1383 GTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEG 1442

Query: 125  LGLRSGS--------YSLP-RNIHIARSQNFRKSTTQASSHNPGEPGRL---APEPEKEQ 172
            + + + +         S+P  N  +A S+    STT   S++P         +P P +  
Sbjct: 1443 ISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGT 1502

Query: 173  VSQSSQPRQAP-------------ASPQEAALDLDVVLIPPPEAF---RDTQPEQCREAS 216
                S P +               AS +  +L     +   P        + P      S
Sbjct: 1503 SIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTS 1562

Query: 217  LPEGPGQQGHTPQLHTPSS-----SQEREQTPSEAMSQKAKETVSTRYTQP--------- 262
            +      +G TP    P S     S E     +  +  K + T ST  +           
Sbjct: 1563 MQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMT 1622

Query: 263  -QPPPAGLP--QNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQ 319
               P  G P   +      P++S E       P+ +  P       V+ S+  S    P 
Sbjct: 1623 ISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSP-------VITSTEVSSSPTPA 1675

Query: 320  HWLSRHTEA-APGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKE 378
               S  T     G + L S +++    A          P D   P    ++  SS    E
Sbjct: 1676 EGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSE 1735

Query: 379  -TRAQHLSPAPGLAQ-PAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVA 436
             T   + +P+ G     + P   +  + +    L+  P     P       ++ +    A
Sbjct: 1736 GTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVT--TSTEATSSPTTA 1793

Query: 437  ASKSMPISIPKAPRANSALTP--PKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSY 494
               S+P S       +  +TP    P S   +  S    L      SN+   +   +SS 
Sbjct: 1794 EGTSIPTST-----LSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSS 1848

Query: 495  LSTEKDASPKTSTSLGKGSFLDKISPSVLRNSRPRPASLGTGKDFAGIQVGKLADLEQEQ 554
             +  +  S  TST     + L  I  S    +     +L T        V   A +    
Sbjct: 1849 PTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSP 1908

Query: 555  SSKRLSYQGQSRDKLPRPPCVSVKIS 580
            ++   S    S  +  RPP  S+ +S
Sbjct: 1909 TTADGSSMPTSTPREGRPPLTSIPVS 1934


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 106/462 (22%), Positives = 164/462 (35%), Gaps = 76/462 (16%)

Query: 35  SSDSSYDFLSTEEKECLLFLEETIGSLDTEADSGLSTDESEPATTPRGFRALPIT----- 89
           +SD+S +   T  KE  +  +ET     T  +   STD  E  T+ +  +++  T     
Sbjct: 226 NSDTSKETSLTVNKETTVETKET-----TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 280

Query: 90  --------QPTPRG-----GPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYS--- 133
                   +PTP+      GP  T T +  TP T  E +S+ P EP    ++S   +   
Sbjct: 281 APTSKVLAKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE 339

Query: 134 -LPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALD 192
             P     A +     + T      P  P   AP   KE    ++  + AP +P+E    
Sbjct: 340 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKE---- 393

Query: 193 LDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAK 252
                 P P   +   P      + P+ P     TP+  TP++ +E   T  E      K
Sbjct: 394 ------PAPTTPKKPAP------TTPKEPAPT--TPKEPTPTTPKEPAPTTKEPAPTTPK 439

Query: 253 ETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRS 312
           E   T   +P P           E AP +  E      AP TT +P    P     ++  
Sbjct: 440 EPAPTAPKKPAP-------TTPKEPAPTTPKEP-----APTTTKEPSPTTPKEPAPTTTK 487

Query: 313 SFHSDPQHWLSRHTEAAPGDSGLISCSLQEQ-----RKARKEALEKLGLPQDQDEPGLHL 367
           S  +  +      T++AP      S +  ++      K       K   P    EP    
Sbjct: 488 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 547

Query: 368 SK---PTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALA----QAPAPAPGP 420
            K   PT++ +P  T  +   PAP   +  AP       P   + LA    + PAP    
Sbjct: 548 PKEPAPTTTKKPAPTTPK--EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605

Query: 421 AQGPLPMKSPAP--GNVAASKSMPISIPKAPRANSALTPPKP 460
              P   + P P      A  +   + P  P+  +  TP +P
Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 105/510 (20%), Positives = 170/510 (33%), Gaps = 64/510 (12%)

Query: 71  TDESEPA-TTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRS 129
           T   EPA TTP+        +P P    E T T       T  E + + P EP     + 
Sbjct: 389 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 448

Query: 130 GSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQP-----RQAPA 184
            + + P+       +    +TT+  S  P  P   AP   K   + + +P     + AP 
Sbjct: 449 PAPTTPKEPAPTTPKEPAPTTTKEPS--PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506

Query: 185 SPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQE------ 238
           +P+E          P P   ++  P   +E +          TP+   P++ +E      
Sbjct: 507 TPKE----------PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 556

Query: 239 ---REQTPSEAMSQKAKETVSTRY-------------TQPQPPPAGLPQN---ARAEDAP 279
                 TP E      KET  T               T P+ P    P+       E+  
Sbjct: 557 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 616

Query: 280 LSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCS 339
            ++ E+P         P   K P     K    +   +P     + T A     G    +
Sbjct: 617 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET-APTTPKGTAPTT 675

Query: 340 LQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQA 399
           L+E      +       P  ++       +PTS+   K         AP   +  AP   
Sbjct: 676 LKEPAPTTPKK------PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 729

Query: 400 SAAIPAAGKALA----QAPAPAPGPAQGP---LPMKSPAPGNVAASKSMPI----SIPKA 448
               P   K  A    + PAP       P    P  +  P +  + K  P     + P  
Sbjct: 730 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 789

Query: 449 PRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTS 508
           P+  +  TP KP    T  E+  P   +++  + T E + +  S   ST + ++  T  +
Sbjct: 790 PKEPAPTTPKKPAP--TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 847

Query: 509 LGKGSFLDKISPSVLRNSRPRPASLGTGKD 538
           L + S  +   P+    +  +P    T KD
Sbjct: 848 L-ENSPKEPGVPTTKTPAATKPEMTTTAKD 876



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 98/470 (20%), Positives = 151/470 (32%), Gaps = 76/470 (16%)

Query: 13  SEPVTRVGSCDSMMSSTSTRSGSSDSSY--DFLSTEEKECLLFLEETIGSLDTEADSGLS 70
           SE +T   S      S+S+ S SS SS      S++       L++ +   D + +    
Sbjct: 110 SEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK 169

Query: 71  TDESEPATTPRGFRALP-----ITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGL 125
               +P         L      +T P       +T T Q     T  + +++ P  P+  
Sbjct: 170 KPTPKPPVVDEAGSGLDNGDFKVTTP-------DTSTTQHNKVSTSPKITTAKPINPRP- 221

Query: 126 GLRSGSYSLPRNIHIAR--SQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAP 183
                  SLP N   ++  S    K TT  +        + + + +++  S         
Sbjct: 222 -------SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 274

Query: 184 ASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTP 243
            S ++ A    V+  P P+A   T+           GP     TP+  TP+       TP
Sbjct: 275 TSAKDLAPTSKVLAKPTPKAETTTK-----------GPALT--TPKEPTPT-------TP 314

Query: 244 SEAMSQKAKE-TVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLP 302
            E  S   KE T +T  + P  P    P   ++  AP +  E      AP TT +P    
Sbjct: 315 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS--APTTPKEP-----APTTTKEPAPTT 367

Query: 303 PNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDE 362
           P    K    +   +P    ++     P              K       K   P    E
Sbjct: 368 P----KEPAPTTTKEPAPTTTKSAPTTP--------------KEPAPTTPKKPAPTTPKE 409

Query: 363 PGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQ 422
           P     K  +   PKE       PAP   +  AP       P   K       PAP   +
Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE------PAPTTPK 463

Query: 423 GPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTP 472
            P P  +  P      +  P +   AP       P   +S  T  +  +P
Sbjct: 464 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 513



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 73/371 (19%), Positives = 130/371 (35%), Gaps = 29/371 (7%)

Query: 99  ETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNP 158
           E+   +   P +   S  + PP      ++S +   P+  +  +++   +S      H+ 
Sbjct: 60  ESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSV 119

Query: 159 GEPGRLAPEPEKEQVSQSSQPRQAPASPQEAA-LDLDVVLIPPPEAFRDTQPEQCREASL 217
            E    +        S SS  R+  +S   AA  +L   L       +D +  + ++   
Sbjct: 120 SENQESSSSSSSS--SSSSTIRKIKSSKNSAANRELQKKL-----KVKDNKKNRTKKKPT 172

Query: 218 PEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQP--PPAGLPQNA-R 274
           P+ P        L    +   +  TP  + +Q  K + S + T  +P  P   LP N+  
Sbjct: 173 PKPPVVDEAGSGL---DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 229

Query: 275 AEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSG 334
           +++  L+  ++        TT   +        K   +S         +   + AP    
Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDG---KEKTTSAKETQSIEKTSAKDLAPTSKV 286

Query: 335 LISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPA 394
           L   + + +   +  AL          EP     K  +S  PKE     +  AP   +  
Sbjct: 287 LAKPTPKAETTTKGPALTT------PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340

Query: 395 APAQASAAIPAAGKALA----QAPAPAPGPAQGPLPMKSPAPGNVAASKSMPIS-IPKAP 449
           AP    +A P   K  A    + PAP       P   K PAP    ++ + P    P  P
Sbjct: 341 APTTTKSA-PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 399

Query: 450 RANSALTPPKP 460
           +  +  TP +P
Sbjct: 400 KKPAPTTPKEP 410



 Score = 36.6 bits (83), Expect = 0.068
 Identities = 45/214 (21%), Positives = 76/214 (35%), Gaps = 27/214 (12%)

Query: 59  GSLDTEADSGLSTDESEPA-TTPRGFRALPITQPTP----RGGPEE----------TITQ 103
           G+  T       T   EPA TTP+G     + +P P    +  P+E          + T 
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774

Query: 104 QGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR 163
               P T  E++ + P EP     +  + + P       S+    +TT+  +     P  
Sbjct: 775 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 834

Query: 164 LAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQ 223
             PE     +S    P+    SP+E         +P  +    T+PE    A        
Sbjct: 835 STPE-----LSAEPTPKALENSPKEPG-------VPTTKTPAATKPEMTTTAKDKTTERD 882

Query: 224 QGHTPQLHTPSSSQEREQTPSEAMSQKAKETVST 257
              TP+  T +    +E   +   + ++K T +T
Sbjct: 883 LRTTPETTTAAPKMTKETATTTEKTTESKITATT 916


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 106/462 (22%), Positives = 164/462 (35%), Gaps = 76/462 (16%)

Query: 35  SSDSSYDFLSTEEKECLLFLEETIGSLDTEADSGLSTDESEPATTPRGFRALPIT----- 89
           +SD+S +   T  KE  +  +ET     T  +   STD  E  T+ +  +++  T     
Sbjct: 267 NSDTSKETSLTVNKETTVETKET-----TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 321

Query: 90  --------QPTPRG-----GPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYS--- 133
                   +PTP+      GP  T T +  TP T  E +S+ P EP    ++S   +   
Sbjct: 322 APTSKVLAKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE 380

Query: 134 -LPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALD 192
             P     A +     + T      P  P   AP   KE    ++  + AP +P+E    
Sbjct: 381 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKE---- 434

Query: 193 LDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAK 252
                 P P   +   P      + P+ P     TP+  TP++ +E   T  E      K
Sbjct: 435 ------PAPTTPKKPAP------TTPKEPAPT--TPKEPTPTTPKEPAPTTKEPAPTTPK 480

Query: 253 ETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRS 312
           E   T   +P P           E AP +  E      AP TT +P    P     ++  
Sbjct: 481 EPAPTAPKKPAP-------TTPKEPAPTTPKEP-----APTTTKEPSPTTPKEPAPTTTK 528

Query: 313 SFHSDPQHWLSRHTEAAPGDSGLISCSLQEQ-----RKARKEALEKLGLPQDQDEPGLHL 367
           S  +  +      T++AP      S +  ++      K       K   P    EP    
Sbjct: 529 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 588

Query: 368 SK---PTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALA----QAPAPAPGP 420
            K   PT++ +P  T  +   PAP   +  AP       P   + LA    + PAP    
Sbjct: 589 PKEPAPTTTKKPAPTTPK--EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646

Query: 421 AQGPLPMKSPAP--GNVAASKSMPISIPKAPRANSALTPPKP 460
              P   + P P      A  +   + P  P+  +  TP +P
Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 105/510 (20%), Positives = 170/510 (33%), Gaps = 64/510 (12%)

Query: 71  TDESEPA-TTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRS 129
           T   EPA TTP+        +P P    E T T       T  E + + P EP     + 
Sbjct: 430 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 489

Query: 130 GSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQP-----RQAPA 184
            + + P+       +    +TT+  S  P  P   AP   K   + + +P     + AP 
Sbjct: 490 PAPTTPKEPAPTTPKEPAPTTTKEPS--PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 547

Query: 185 SPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQE------ 238
           +P+E          P P   ++  P   +E +          TP+   P++ +E      
Sbjct: 548 TPKE----------PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 597

Query: 239 ---REQTPSEAMSQKAKETVSTRY-------------TQPQPPPAGLPQN---ARAEDAP 279
                 TP E      KET  T               T P+ P    P+       E+  
Sbjct: 598 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 657

Query: 280 LSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCS 339
            ++ E+P         P   K P     K    +   +P     + T A     G    +
Sbjct: 658 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET-APTTPKGTAPTT 716

Query: 340 LQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQA 399
           L+E      +       P  ++       +PTS+   K         AP   +  AP   
Sbjct: 717 LKEPAPTTPKK------PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 770

Query: 400 SAAIPAAGKALA----QAPAPAPGPAQGP---LPMKSPAPGNVAASKSMPI----SIPKA 448
               P   K  A    + PAP       P    P  +  P +  + K  P     + P  
Sbjct: 771 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 830

Query: 449 PRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTS 508
           P+  +  TP KP    T  E+  P   +++  + T E + +  S   ST + ++  T  +
Sbjct: 831 PKEPAPTTPKKPAP--TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 888

Query: 509 LGKGSFLDKISPSVLRNSRPRPASLGTGKD 538
           L + S  +   P+    +  +P    T KD
Sbjct: 889 L-ENSPKEPGVPTTKTPAATKPEMTTTAKD 917



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 98/470 (20%), Positives = 151/470 (32%), Gaps = 76/470 (16%)

Query: 13  SEPVTRVGSCDSMMSSTSTRSGSSDSSY--DFLSTEEKECLLFLEETIGSLDTEADSGLS 70
           SE +T   S      S+S+ S SS SS      S++       L++ +   D + +    
Sbjct: 151 SEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKK 210

Query: 71  TDESEPATTPRGFRALP-----ITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGL 125
               +P         L      +T P       +T T Q     T  + +++ P  P+  
Sbjct: 211 KPTPKPPVVDEAGSGLDNGDFKVTTP-------DTSTTQHNKVSTSPKITTAKPINPRP- 262

Query: 126 GLRSGSYSLPRNIHIAR--SQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAP 183
                  SLP N   ++  S    K TT  +        + + + +++  S         
Sbjct: 263 -------SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 315

Query: 184 ASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTP 243
            S ++ A    V+  P P+A   T+           GP     TP+  TP+       TP
Sbjct: 316 TSAKDLAPTSKVLAKPTPKAETTTK-----------GPALT--TPKEPTPT-------TP 355

Query: 244 SEAMSQKAKE-TVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLP 302
            E  S   KE T +T  + P  P    P   ++  AP +  E      AP TT +P    
Sbjct: 356 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS--APTTPKEP-----APTTTKEPAPTT 408

Query: 303 PNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDE 362
           P    K    +   +P    ++     P              K       K   P    E
Sbjct: 409 P----KEPAPTTTKEPAPTTTKSAPTTP--------------KEPAPTTPKKPAPTTPKE 450

Query: 363 PGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQ 422
           P     K  +   PKE       PAP   +  AP       P   K       PAP   +
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE------PAPTTPK 504

Query: 423 GPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTP 472
            P P  +  P      +  P +   AP       P   +S  T  +  +P
Sbjct: 505 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 554



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 73/371 (19%), Positives = 130/371 (35%), Gaps = 29/371 (7%)

Query: 99  ETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNP 158
           E+   +   P +   S  + PP      ++S +   P+  +  +++   +S      H+ 
Sbjct: 101 ESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSV 160

Query: 159 GEPGRLAPEPEKEQVSQSSQPRQAPASPQEAA-LDLDVVLIPPPEAFRDTQPEQCREASL 217
            E    +        S SS  R+  +S   AA  +L   L       +D +  + ++   
Sbjct: 161 SENQESSSSSSSS--SSSSTIRKIKSSKNSAANRELQKKL-----KVKDNKKNRTKKKPT 213

Query: 218 PEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQP--PPAGLPQNA-R 274
           P+ P        L    +   +  TP  + +Q  K + S + T  +P  P   LP N+  
Sbjct: 214 PKPPVVDEAGSGL---DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDT 270

Query: 275 AEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSG 334
           +++  L+  ++        TT   +        K   +S         +   + AP    
Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDG---KEKTTSAKETQSIEKTSAKDLAPTSKV 327

Query: 335 LISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPA 394
           L   + + +   +  AL          EP     K  +S  PKE     +  AP   +  
Sbjct: 328 LAKPTPKAETTTKGPALTT------PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381

Query: 395 APAQASAAIPAAGKALA----QAPAPAPGPAQGPLPMKSPAPGNVAASKSMPIS-IPKAP 449
           AP    +A P   K  A    + PAP       P   K PAP    ++ + P    P  P
Sbjct: 382 APTTTKSA-PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 440

Query: 450 RANSALTPPKP 460
           +  +  TP +P
Sbjct: 441 KKPAPTTPKEP 451



 Score = 36.6 bits (83), Expect = 0.068
 Identities = 45/214 (21%), Positives = 76/214 (35%), Gaps = 27/214 (12%)

Query: 59  GSLDTEADSGLSTDESEPA-TTPRGFRALPITQPTP----RGGPEE----------TITQ 103
           G+  T       T   EPA TTP+G     + +P P    +  P+E          + T 
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815

Query: 104 QGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR 163
               P T  E++ + P EP     +  + + P       S+    +TT+  +     P  
Sbjct: 816 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 875

Query: 164 LAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQ 223
             PE     +S    P+    SP+E         +P  +    T+PE    A        
Sbjct: 876 STPE-----LSAEPTPKALENSPKEPG-------VPTTKTPAATKPEMTTTAKDKTTERD 923

Query: 224 QGHTPQLHTPSSSQEREQTPSEAMSQKAKETVST 257
              TP+  T +    +E   +   + ++K T +T
Sbjct: 924 LRTTPETTTAAPKMTKETATTTEKTTESKITATT 957


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 62.8 bits (151), Expect = 9e-10
 Identities = 115/553 (20%), Positives = 202/553 (36%), Gaps = 70/553 (12%)

Query: 63  TEADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEP 122
           T     L   + EP   P+        +P+P    ++   ++   PR+ + S S      
Sbjct: 239 TSTSDILKVPKPEPIPEPK--------EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRS 290

Query: 123 QGLGLRSGSYSLPRNIHIARSQNF----RKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQ 178
                RS S++ PR  H +RS+++    R S  +  S     P R  P P + + S+S  
Sbjct: 291 -----RSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPV 345

Query: 179 PRQ----APASPQEAALDLDVVLIPP--PEAFRDTQPEQCREASLPEGPGQQGHTPQLH- 231
            R+    A  S   ++        PP  P     + P + R  S    P ++ H P    
Sbjct: 346 RRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPA 405

Query: 232 TPSSSQEREQTPSEA-MSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRL 290
           TP        TP ++  ++K++ +VS   T  +                ++  +    R 
Sbjct: 406 TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGK----------------VTKHKGTEKRE 449

Query: 291 APLTTPKPRK--LPPNIVLKSSRSSFHSDPQH--WLSRHTEAAPGDSGLISCSLQEQRKA 346
           +P   PKPRK  L  +   K  + +     Q      R  + +  DSG  S S  E  + 
Sbjct: 450 SPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSG--SSSSSEDERP 507

Query: 347 RKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQ---HLSPAPGLAQPAAPAQASAAI 403
           ++  ++   + + +       + P+   R KET  +     SP+P    P    ++ +  
Sbjct: 508 KRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP---PPTRRRRSPSPA 564

Query: 404 PAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESG 463
           P   +     P P       P   +SP+P   +       S    P+  +A  PP P+  
Sbjct: 565 PPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR 624

Query: 464 LT------LQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGKGSFLDK 517
            +       + S++P  +Q +  S   +R    LSS     K +SP  ST   +      
Sbjct: 625 ASPSPPPKRRVSHSPPPKQRS--SPVTKRRSPSLSS--KHRKGSSPSRSTREARSP---- 676

Query: 518 ISPSVLRNSRPRPASLGTGKDFAGIQVGKLADLEQEQSSKRLSYQGQSRDKLPRPPCVSV 577
             P+   +  PRP +  T      ++ G  +  ++ QS    +   +   + P P  +  
Sbjct: 677 -QPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKK 735

Query: 578 KISPKGVPNEHRR 590
             SP   P   RR
Sbjct: 736 AASPS--PQSVRR 746



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 89/413 (21%), Positives = 145/413 (35%), Gaps = 50/413 (12%)

Query: 74  SEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTE-------SSSSHPPEPQGLG 126
           S PAT P   R  P  Q + R          GRT   VT+        S S  P+P+ + 
Sbjct: 402 SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE 461

Query: 127 LRSGSYSLPRNIHIARS----QNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQA 182
           L          +  A S    + +R+   Q+SS +          P++  V      R+ 
Sbjct: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRR 521

Query: 183 PASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQE---- 238
             SP  +A         P +  ++T P   R  S    P ++  +P    P   +     
Sbjct: 522 RHSPSRSASP------SPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTP 575

Query: 239 --REQTPSEAMSQKAKET------VSTRYTQPQPPPAGL------PQNARAEDAP----- 279
             R +TPS    +++         +  RY+ P PPP         P   RA  +P     
Sbjct: 576 PPRRRTPSPPPRRRSPSPRRYSPPIQRRYS-PSPPPKRRTASPPPPPKRRASPSPPPKRR 634

Query: 280 LSSGEDPNSRLAPLTTPKPRKLPPNIVLKSS--RSSFHSDPQHWLSRHTEAAPGDSGLIS 337
           +S    P  R +P+T  +   L       SS  RS+  +       RH+ +    +   S
Sbjct: 635 VSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTS 694

Query: 338 CSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPA 397
            S    R+    + ++   P     P   +S+      PK+ + +  SP+P   Q     
Sbjct: 695 SSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE---PKKIK-KAASPSP---QSVRRV 747

Query: 398 QASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPR 450
            +S ++  + +  A+ P   P P Q   P  + +P         P   P  PR
Sbjct: 748 SSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPR 800



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 82/363 (22%), Positives = 125/363 (34%), Gaps = 48/363 (13%)

Query: 91  PTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLP-RNIHIARSQNFRKS 149
           P+PR   +ET      +PR     S S PP  +    RS S + P R          R++
Sbjct: 531 PSPRKRQKET------SPRGRRRRSPSPPPTRRR---RSPSPAPPPRRRRTPTPPPRRRT 581

Query: 150 TTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQP 209
            +         P R +P P + + S S  P++  ASP            PPP+      P
Sbjct: 582 PSPPPRRRSPSPRRYSP-PIQRRYSPSPPPKRRTASPP-----------PPPKRRASPSP 629

Query: 210 EQCREASLPEGPGQQG------HTPQL---HTPSSSQEREQTPSEAMSQKAKETVSTRYT 260
              R  S    P Q+        +P L   H   SS  R    + +     + + S R  
Sbjct: 630 PPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 689

Query: 261 QPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLT----TPKPRKL-------PPNIVLKS 309
            PQ   +  P    A  +P    + P+    P+     TP+P+K+       P ++   S
Sbjct: 690 APQTSSSPPPVRRGASSSP-QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVS 748

Query: 310 SRSSFHSDPQHWLSRHTEAAPG----DSGLISCSLQEQRKARKEALEKLGLPQDQDEPGL 365
           S  S    P+   ++   A P      S   + S     K  K        P++ D+ G 
Sbjct: 749 SSRSVSGSPEP-AAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGG 807

Query: 366 HLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPL 425
              K     +  +   +H        + A  A A+AA+  A  A A        P   P 
Sbjct: 808 GKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPE 867

Query: 426 PMK 428
           P K
Sbjct: 868 PKK 870



 Score = 34.7 bits (78), Expect = 0.26
 Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 9/127 (7%)

Query: 64  EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQ 123
           EA S        P+  PR  +      P  RG       +Q  +P T      S  PEP+
Sbjct: 672 EARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPK 731

Query: 124 GLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAP 183
              ++  +   P+++        R S++++ S +P    +  P P     SQS     +P
Sbjct: 732 --KIKKAASPSPQSVR-------RVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSP 782

Query: 184 ASPQEAA 190
           A P + A
Sbjct: 783 AVPVKKA 789


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 109/446 (24%), Positives = 158/446 (35%), Gaps = 86/446 (19%)

Query: 64  EADSGLSTDESEPA--TTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPE 121
           EAD   ++ E+ P   T PR    L      P G P          PR  +ES++  PP 
Sbjct: 266 EADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPA-------PRKASESTTPAPPT 318

Query: 122 PQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRL--APEPEKEQVSQSSQP 179
           P+           PR+    + +N  +    +S  N    GRL   P P+     + S+ 
Sbjct: 319 PR-----------PRSS--LQQENLVEQAGSSSLVN----GRLHELPVPKPRGTPKPSEG 361

Query: 180 RQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQ------GHTPQLHTP 233
             AP          D   I   +A    +P     +S P  P Q       G T ++  P
Sbjct: 362 TPAPRK--------DPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQP 413

Query: 234 SSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPL 293
           S +   E  P     ++ ++          P  A  P     E  P S    P   + P 
Sbjct: 414 SPTASLESKPYNPFEEEEED--KEEEAPAAPSLATSPALGHPESTPKSL--HPWYGITPT 469

Query: 294 TTPKPRKLPPN-------IVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKA 346
           ++PK +K P         + L +SR S HS+P          +P  S     S    + A
Sbjct: 470 SSPKTKKRPAPRAPSASPLALHASRLS-HSEPPS-----ATPSPALSVESLSSESASQTA 523

Query: 347 RKEALEKLGLPQDQDEPGLHL-------------SKPTSSIRPKETRAQHLSPA-PGLA- 391
             E LE   +P+   EP +H              S   SS    E R + +  A PGLA 
Sbjct: 524 GAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAP 583

Query: 392 --------QPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPI 443
                   QPA P   +   P       ++P P+PG +   L +KS    N    K  P 
Sbjct: 584 RTRGSSGPQPAKPCSGATPTPLLLVG-DRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPA 642

Query: 444 SIP---KAPRANSALTPPKPESGLTL 466
           + P   KA + +  + PP P  G  L
Sbjct: 643 ASPATKKATKGSKPVRPPAPGHGFPL 668


>gi|226437579 NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 97/435 (22%), Positives = 148/435 (34%), Gaps = 62/435 (14%)

Query: 64   EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEP- 122
            +A+ GL+  +    T P   +   ++           ++QQ     T+ + S+  PP P 
Sbjct: 629  QAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 688

Query: 123  QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR-----LAPEPEKEQVSQSS 177
            Q   L S    +     +++      +  Q S+  P  P +      AP+P       S 
Sbjct: 689  QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ 748

Query: 178  QPRQAPASPQEAAL-------DLDVVLIPPPEAFRDTQPEQCREA-SLPEGPGQQGHTPQ 229
            Q  +    PQ++A+       D D+   P P A      +Q  E  +LP+        P 
Sbjct: 749  QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL 808

Query: 230  LHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSR 289
              T  SS  +    +  +SQ+A+E ++        PP  L      +D  LSS   P + 
Sbjct: 809  QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL------QDTDLSSAPKPVAA 862

Query: 290  LAP--------LTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQ 341
              P        LT P+   + P + L+ +  S    P         A P           
Sbjct: 863  ATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV------AAATP----------- 905

Query: 342  EQRKARKEALEKLGLPQDQDEPG---LHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQ 398
                  ++A E L LPQD        L  + PTS   P          A     P     
Sbjct: 906  ----VSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPV 961

Query: 399  ASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRA------- 451
            A+ A    G+AL   PAP    A  P   +  A   V      P +    P A       
Sbjct: 962  ATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADS 1021

Query: 452  ---NSALTPPKPESG 463
                 AL+ P+P SG
Sbjct: 1022 TLGMEALSLPEPASG 1036



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 93/403 (23%), Positives = 142/403 (35%), Gaps = 40/403 (9%)

Query: 101 ITQQGRTPRTVTESSSSHPPEP-QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPG 159
           + +Q +   T+ + S+  PP P Q   L S    +     +++      +  Q S   P 
Sbjct: 586 VPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPP 645

Query: 160 EPGR-----LAPEPEKEQVSQSSQPRQAPASPQEAAL-------DLDVVLIPPPEAFRDT 207
            P +      AP+P       S Q  +    PQ++A+       D D+   P P A    
Sbjct: 646 LPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATL 705

Query: 208 QPEQCREA-SLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPP 266
             +Q  E  +LP+        P   T  SS  +    +  +SQ+A+E ++        PP
Sbjct: 706 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP 765

Query: 267 AGLPQNARAEDAPLSSGEDPNSRLA--------PLTTPKPRKLPPNIVLKSSRSSFHSDP 318
             L      +D  LSS   P +            LT P+   + P + L+ +  S    P
Sbjct: 766 LPL------QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 819

Query: 319 QHWLSRHTEAA------PGDSGLIS-CSLQEQRKARKEALEKLGLPQDQD-EPGLHLSKP 370
               +  ++ A      P DS +     LQ+   +          P  Q  E GL L + 
Sbjct: 820 VAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQD 879

Query: 371 TSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPA-PAPGPAQGPLPMKS 429
           ++   P   +   LS AP     A P    A     G  L Q  A  AP P Q   P   
Sbjct: 880 SAMTPPLPLQDTDLSSAPKPVAAATPVSQQAE---EGLTLPQDSAMTAPLPLQDTGPTSG 936

Query: 430 PAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTP 472
           P P  VA  +++      AP      T  + E G  L     P
Sbjct: 937 PEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAP 979



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 85/375 (22%), Positives = 134/375 (35%), Gaps = 43/375 (11%)

Query: 64   EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHP-PEP 122
            +A+ GL+  +    T P     LP+    P  GPE        TP+T+   +   P  EP
Sbjct: 909  QAEEGLTLPQDSAMTAP-----LPLQDTGPTSGPEPLAVA---TPQTLQAEAGCAPGTEP 960

Query: 123  QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQA 182
                 +           +  +   R +  + ++  P  P   A +  ++   Q +     
Sbjct: 961  VATMAQQ---------EVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGT 1011

Query: 183  PASPQEAA---LDLDVVLIPPP---------EAFRDTQPEQCREASLPEGPGQQGHTPQL 230
            P + QE A   L ++ + +P P         EA      E C EA    G G +  +PQ 
Sbjct: 1012 PWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQK 1071

Query: 231  HT-PSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSR 289
             T    +Q+       A     +  +      P  PPA  P+ ++A    L S       
Sbjct: 1072 ETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQAR---LLSPAREERG 1128

Query: 290  LAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKE 349
            L+  +TP+P  LP  +  ++S  S        +S      P      S    +Q     E
Sbjct: 1129 LSGKSTPEP-TLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ----PE 1183

Query: 350  ALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKA 409
             +  LG  +   E    L  P   ++P E  A+   P+  + +P  P   SA    AG A
Sbjct: 1184 PVLGLGSVEQPHEVPSVLGTPL--LQPPENLAKG-QPSTPVDRPLGP-DPSAPGTLAGAA 1239

Query: 410  LAQAPAPAPGPAQGP 424
            L     PAP   Q P
Sbjct: 1240 LPPLEPPAPCLCQDP 1254


>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 97/435 (22%), Positives = 148/435 (34%), Gaps = 62/435 (14%)

Query: 64   EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEP- 122
            +A+ GL+  +    T P   +   ++           ++QQ     T+ + S+  PP P 
Sbjct: 629  QAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 688

Query: 123  QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR-----LAPEPEKEQVSQSS 177
            Q   L S    +     +++      +  Q S+  P  P +      AP+P       S 
Sbjct: 689  QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ 748

Query: 178  QPRQAPASPQEAAL-------DLDVVLIPPPEAFRDTQPEQCREA-SLPEGPGQQGHTPQ 229
            Q  +    PQ++A+       D D+   P P A      +Q  E  +LP+        P 
Sbjct: 749  QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL 808

Query: 230  LHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSR 289
              T  SS  +    +  +SQ+A+E ++        PP  L      +D  LSS   P + 
Sbjct: 809  QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL------QDTDLSSAPKPVAA 862

Query: 290  LAP--------LTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQ 341
              P        LT P+   + P + L+ +  S    P         A P           
Sbjct: 863  ATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV------AAATP----------- 905

Query: 342  EQRKARKEALEKLGLPQDQDEPG---LHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQ 398
                  ++A E L LPQD        L  + PTS   P          A     P     
Sbjct: 906  ----VSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPV 961

Query: 399  ASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRA------- 451
            A+ A    G+AL   PAP    A  P   +  A   V      P +    P A       
Sbjct: 962  ATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADS 1021

Query: 452  ---NSALTPPKPESG 463
                 AL+ P+P SG
Sbjct: 1022 TLGMEALSLPEPASG 1036



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 93/403 (23%), Positives = 142/403 (35%), Gaps = 40/403 (9%)

Query: 101 ITQQGRTPRTVTESSSSHPPEP-QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPG 159
           + +Q +   T+ + S+  PP P Q   L S    +     +++      +  Q S   P 
Sbjct: 586 VPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPP 645

Query: 160 EPGR-----LAPEPEKEQVSQSSQPRQAPASPQEAAL-------DLDVVLIPPPEAFRDT 207
            P +      AP+P       S Q  +    PQ++A+       D D+   P P A    
Sbjct: 646 LPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATL 705

Query: 208 QPEQCREA-SLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPP 266
             +Q  E  +LP+        P   T  SS  +    +  +SQ+A+E ++        PP
Sbjct: 706 VSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPP 765

Query: 267 AGLPQNARAEDAPLSSGEDPNSRLA--------PLTTPKPRKLPPNIVLKSSRSSFHSDP 318
             L      +D  LSS   P +            LT P+   + P + L+ +  S    P
Sbjct: 766 LPL------QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 819

Query: 319 QHWLSRHTEAA------PGDSGLIS-CSLQEQRKARKEALEKLGLPQDQD-EPGLHLSKP 370
               +  ++ A      P DS +     LQ+   +          P  Q  E GL L + 
Sbjct: 820 VAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQD 879

Query: 371 TSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPA-PAPGPAQGPLPMKS 429
           ++   P   +   LS AP     A P    A     G  L Q  A  AP P Q   P   
Sbjct: 880 SAMTPPLPLQDTDLSSAPKPVAAATPVSQQAE---EGLTLPQDSAMTAPLPLQDTGPTSG 936

Query: 430 PAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTP 472
           P P  VA  +++      AP      T  + E G  L     P
Sbjct: 937 PEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAP 979



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 85/375 (22%), Positives = 134/375 (35%), Gaps = 43/375 (11%)

Query: 64   EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHP-PEP 122
            +A+ GL+  +    T P     LP+    P  GPE        TP+T+   +   P  EP
Sbjct: 909  QAEEGLTLPQDSAMTAP-----LPLQDTGPTSGPEPLAVA---TPQTLQAEAGCAPGTEP 960

Query: 123  QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQA 182
                 +           +  +   R +  + ++  P  P   A +  ++   Q +     
Sbjct: 961  VATMAQQ---------EVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGT 1011

Query: 183  PASPQEAA---LDLDVVLIPPP---------EAFRDTQPEQCREASLPEGPGQQGHTPQL 230
            P + QE A   L ++ + +P P         EA      E C EA    G G +  +PQ 
Sbjct: 1012 PWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQK 1071

Query: 231  HT-PSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSR 289
             T    +Q+       A     +  +      P  PPA  P+ ++A    L S       
Sbjct: 1072 ETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQAR---LLSPAREERG 1128

Query: 290  LAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKE 349
            L+  +TP+P  LP  +  ++S  S        +S      P      S    +Q     E
Sbjct: 1129 LSGKSTPEP-TLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ----PE 1183

Query: 350  ALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKA 409
             +  LG  +   E    L  P   ++P E  A+   P+  + +P  P   SA    AG A
Sbjct: 1184 PVLGLGSVEQPHEVPSVLGTPL--LQPPENLAKG-QPSTPVDRPLGP-DPSAPGTLAGAA 1239

Query: 410  LAQAPAPAPGPAQGP 424
            L     PAP   Q P
Sbjct: 1240 LPPLEPPAPCLCQDP 1254


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 104/447 (23%), Positives = 158/447 (35%), Gaps = 103/447 (23%)

Query: 35  SSDSSYDFLSTEEKECLLFLEETIGSLDTEADSGLSTDESEPATTPRGFRALPIT----- 89
           +SD+S +   T  KE  +  +ET     T  +   STD  E  T+ +  +++  T     
Sbjct: 133 NSDTSKETSLTVNKETTVETKET-----TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187

Query: 90  --------QPTPRG-----GPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPR 136
                   +PTP+      GP  T T +  TP T  E +S+ P EP    ++S   +   
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT--- 243

Query: 137 NIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVV 196
                  +    +TT+++   P EP   AP   KE          AP +P+E A      
Sbjct: 244 ------PKEPAPTTTKSAPTTPKEP---APTTTKEP---------APTTPKEPAPTTTKE 285

Query: 197 LIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVS 256
             P       T P++    + P+ P     TP+   P++ +E   T  +  +   KE   
Sbjct: 286 PAPTTTKSAPTTPKEPAPTT-PKKPAPT--TPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 342

Query: 257 TRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHS 316
           T   +P P     P     ++   ++ ++P    AP TT +P    P             
Sbjct: 343 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEP----APTTTKEPSPTTPK------------ 386

Query: 317 DPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRP 376
                     E AP  +     + +E      ++      P    EP    +K  +   P
Sbjct: 387 ----------EPAPTTTKSAPTTTKEPAPTTTKSA-----PTTPKEPSPTTTKEPAPTTP 431

Query: 377 KETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVA 436
           KE       PAP    P  PA  +   PA      + PAP       P   K PAP    
Sbjct: 432 KE-------PAP--TTPKKPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAP---- 476

Query: 437 ASKSMPISIPK--APRANSALTPPKPE 461
                  + PK  AP     LTP  PE
Sbjct: 477 -------TTPKETAPTTPKKLTPTTPE 496



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 105/510 (20%), Positives = 170/510 (33%), Gaps = 64/510 (12%)

Query: 71  TDESEPA-TTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRS 129
           T   EPA TTP+        +P P    E T T       T  E + + P EP     + 
Sbjct: 296 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 355

Query: 130 GSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQP-----RQAPA 184
            + + P+       +    +TT+  S  P  P   AP   K   + + +P     + AP 
Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPS--PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413

Query: 185 SPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQE------ 238
           +P+E          P P   ++  P   +E +          TP+   P++ +E      
Sbjct: 414 TPKE----------PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463

Query: 239 ---REQTPSEAMSQKAKETVSTRY-------------TQPQPPPAGLPQN---ARAEDAP 279
                 TP E      KET  T               T P+ P    P+       E+  
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 523

Query: 280 LSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCS 339
            ++ E+P         P   K P     K    +   +P     + T A     G    +
Sbjct: 524 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET-APTTPKGTAPTT 582

Query: 340 LQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQA 399
           L+E      +       P  ++       +PTS+   K         AP   +  AP   
Sbjct: 583 LKEPAPTTPKK------PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 636

Query: 400 SAAIPAAGKALA----QAPAPAPGPAQGP---LPMKSPAPGNVAASKSMPI----SIPKA 448
               P   K  A    + PAP       P    P  +  P +  + K  P     + P  
Sbjct: 637 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 696

Query: 449 PRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTS 508
           P+  +  TP KP    T  E+  P   +++  + T E + +  S   ST + ++  T  +
Sbjct: 697 PKEPAPTTPKKPAP--TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754

Query: 509 LGKGSFLDKISPSVLRNSRPRPASLGTGKD 538
           L + S  +   P+    +  +P    T KD
Sbjct: 755 L-ENSPKEPGVPTTKTPAATKPEMTTTAKD 783



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 89/416 (21%), Positives = 139/416 (33%), Gaps = 55/416 (13%)

Query: 70  STDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRS 129
           +T  ++ +T+P+   A PI  P P   P    +++  T  TV + ++    E      ++
Sbjct: 106 TTQHNKVSTSPKITTAKPIN-PRPSLPPNSDTSKE--TSLTVNKETTVETKETTTTNKQT 162

Query: 130 GSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQS---SQPRQ-APAS 185
            +    +      +Q+  K  T A    P       P P+ E  ++    + P++  P +
Sbjct: 163 STDGKEKTTSAKETQSIEK--TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT 220

Query: 186 PQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSE 245
           P+E A                T P++    ++   P     TP+   P++++    TP E
Sbjct: 221 PKEPA---------------STTPKEPTPTTIKSAPT----TPKEPAPTTTKSAPTTPKE 261

Query: 246 AMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPR----KL 301
                 KE   T   +P P     P     + AP +  E      AP T  KP     K 
Sbjct: 262 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-----APTTPKKPAPTTPKE 316

Query: 302 PPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQD 361
           P     K    +   +P           P +            K       K   P    
Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA------PTAPKKPAPTTPKEPAPTTPK 370

Query: 362 EPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGK----ALAQAPAPA 417
           EP    +K  S   PKE        AP   +  AP    +A P   K       + PAP 
Sbjct: 371 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-PTTPKEPSPTTTKEPAPT 429

Query: 418 PGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANS----ALTPPKPESGLTLQES 469
                 P   K PAP      K    + PK P   +    A T PK  +  T +E+
Sbjct: 430 TPKEPAPTTPKKPAP---TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 51/233 (21%), Positives = 69/233 (29%), Gaps = 26/233 (11%)

Query: 242 TPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNS--RLAPLTTPKPR 299
           TP E      KE  ST   +P P           E AP ++   P +    AP TT +P 
Sbjct: 212 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA 271

Query: 300 KLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQD 359
              P    K    +   +P    ++     P              K       K   P  
Sbjct: 272 PTTP----KEPAPTTTKEPAPTTTKSAPTTP--------------KEPAPTTPKKPAPTT 313

Query: 360 QDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPG 419
             EP     K  +   PKE       PAP   +  AP       P   K       PAP 
Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE------PAPT 367

Query: 420 PAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTP 472
             + P P  +  P      +  P +   AP       P   +S  T  +  +P
Sbjct: 368 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 420



 Score = 36.6 bits (83), Expect = 0.068
 Identities = 45/214 (21%), Positives = 76/214 (35%), Gaps = 27/214 (12%)

Query: 59  GSLDTEADSGLSTDESEPA-TTPRGFRALPITQPTP----RGGPEE----------TITQ 103
           G+  T       T   EPA TTP+G     + +P P    +  P+E          + T 
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681

Query: 104 QGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR 163
               P T  E++ + P EP     +  + + P       S+    +TT+  +     P  
Sbjct: 682 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 741

Query: 164 LAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQ 223
             PE     +S    P+    SP+E         +P  +    T+PE    A        
Sbjct: 742 STPE-----LSAEPTPKALENSPKEPG-------VPTTKTPAATKPEMTTTAKDKTTERD 789

Query: 224 QGHTPQLHTPSSSQEREQTPSEAMSQKAKETVST 257
              TP+  T +    +E   +   + ++K T +T
Sbjct: 790 LRTTPETTTAAPKMTKETATTTEKTTESKITATT 823


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 104/447 (23%), Positives = 158/447 (35%), Gaps = 103/447 (23%)

Query: 35  SSDSSYDFLSTEEKECLLFLEETIGSLDTEADSGLSTDESEPATTPRGFRALPIT----- 89
           +SD+S +   T  KE  +  +ET     T  +   STD  E  T+ +  +++  T     
Sbjct: 174 NSDTSKETSLTVNKETTVETKET-----TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228

Query: 90  --------QPTPRG-----GPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPR 136
                   +PTP+      GP  T T +  TP T  E +S+ P EP    ++S   +   
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALT-TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT--- 284

Query: 137 NIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVV 196
                  +    +TT+++   P EP   AP   KE          AP +P+E A      
Sbjct: 285 ------PKEPAPTTTKSAPTTPKEP---APTTTKEP---------APTTPKEPAPTTTKE 326

Query: 197 LIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVS 256
             P       T P++    + P+ P     TP+   P++ +E   T  +  +   KE   
Sbjct: 327 PAPTTTKSAPTTPKEPAPTT-PKKPAPT--TPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 383

Query: 257 TRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHS 316
           T   +P P     P     ++   ++ ++P    AP TT +P    P             
Sbjct: 384 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEP----APTTTKEPSPTTPK------------ 427

Query: 317 DPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRP 376
                     E AP  +     + +E      ++      P    EP    +K  +   P
Sbjct: 428 ----------EPAPTTTKSAPTTTKEPAPTTTKSA-----PTTPKEPSPTTTKEPAPTTP 472

Query: 377 KETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVA 436
           KE       PAP    P  PA  +   PA      + PAP       P   K PAP    
Sbjct: 473 KE-------PAP--TTPKKPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAP---- 517

Query: 437 ASKSMPISIPK--APRANSALTPPKPE 461
                  + PK  AP     LTP  PE
Sbjct: 518 -------TTPKETAPTTPKKLTPTTPE 537



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 105/510 (20%), Positives = 170/510 (33%), Gaps = 64/510 (12%)

Query: 71  TDESEPA-TTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRS 129
           T   EPA TTP+        +P P    E T T       T  E + + P EP     + 
Sbjct: 337 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 396

Query: 130 GSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQP-----RQAPA 184
            + + P+       +    +TT+  S  P  P   AP   K   + + +P     + AP 
Sbjct: 397 PAPTTPKEPAPTTPKEPAPTTTKEPS--PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454

Query: 185 SPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQE------ 238
           +P+E          P P   ++  P   +E +          TP+   P++ +E      
Sbjct: 455 TPKE----------PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504

Query: 239 ---REQTPSEAMSQKAKETVSTRY-------------TQPQPPPAGLPQN---ARAEDAP 279
                 TP E      KET  T               T P+ P    P+       E+  
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT 564

Query: 280 LSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCS 339
            ++ E+P         P   K P     K    +   +P     + T A     G    +
Sbjct: 565 PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET-APTTPKGTAPTT 623

Query: 340 LQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQA 399
           L+E      +       P  ++       +PTS+   K         AP   +  AP   
Sbjct: 624 LKEPAPTTPKK------PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 677

Query: 400 SAAIPAAGKALA----QAPAPAPGPAQGP---LPMKSPAPGNVAASKSMPI----SIPKA 448
               P   K  A    + PAP       P    P  +  P +  + K  P     + P  
Sbjct: 678 KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 737

Query: 449 PRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTS 508
           P+  +  TP KP    T  E+  P   +++  + T E + +  S   ST + ++  T  +
Sbjct: 738 PKEPAPTTPKKPAP--TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 795

Query: 509 LGKGSFLDKISPSVLRNSRPRPASLGTGKD 538
           L + S  +   P+    +  +P    T KD
Sbjct: 796 L-ENSPKEPGVPTTKTPAATKPEMTTTAKD 824



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 89/416 (21%), Positives = 139/416 (33%), Gaps = 55/416 (13%)

Query: 70  STDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRS 129
           +T  ++ +T+P+   A PI  P P   P    +++  T  TV + ++    E      ++
Sbjct: 147 TTQHNKVSTSPKITTAKPIN-PRPSLPPNSDTSKE--TSLTVNKETTVETKETTTTNKQT 203

Query: 130 GSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQS---SQPRQ-APAS 185
            +    +      +Q+  K  T A    P       P P+ E  ++    + P++  P +
Sbjct: 204 STDGKEKTTSAKETQSIEK--TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT 261

Query: 186 PQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSE 245
           P+E A                T P++    ++   P     TP+   P++++    TP E
Sbjct: 262 PKEPA---------------STTPKEPTPTTIKSAPT----TPKEPAPTTTKSAPTTPKE 302

Query: 246 AMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPR----KL 301
                 KE   T   +P P     P     + AP +  E      AP T  KP     K 
Sbjct: 303 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP-----APTTPKKPAPTTPKE 357

Query: 302 PPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQD 361
           P     K    +   +P           P +            K       K   P    
Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA------PTAPKKPAPTTPKEPAPTTPK 411

Query: 362 EPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGK----ALAQAPAPA 417
           EP    +K  S   PKE        AP   +  AP    +A P   K       + PAP 
Sbjct: 412 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-PTTPKEPSPTTTKEPAPT 470

Query: 418 PGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANS----ALTPPKPESGLTLQES 469
                 P   K PAP      K    + PK P   +    A T PK  +  T +E+
Sbjct: 471 TPKEPAPTTPKKPAP---TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 523



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 51/233 (21%), Positives = 69/233 (29%), Gaps = 26/233 (11%)

Query: 242 TPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNS--RLAPLTTPKPR 299
           TP E      KE  ST   +P P           E AP ++   P +    AP TT +P 
Sbjct: 253 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA 312

Query: 300 KLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQD 359
              P    K    +   +P    ++     P              K       K   P  
Sbjct: 313 PTTP----KEPAPTTTKEPAPTTTKSAPTTP--------------KEPAPTTPKKPAPTT 354

Query: 360 QDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPG 419
             EP     K  +   PKE       PAP   +  AP       P   K       PAP 
Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE------PAPT 408

Query: 420 PAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTP 472
             + P P  +  P      +  P +   AP       P   +S  T  +  +P
Sbjct: 409 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP 461



 Score = 36.6 bits (83), Expect = 0.068
 Identities = 45/214 (21%), Positives = 76/214 (35%), Gaps = 27/214 (12%)

Query: 59  GSLDTEADSGLSTDESEPA-TTPRGFRALPITQPTP----RGGPEE----------TITQ 103
           G+  T       T   EPA TTP+G     + +P P    +  P+E          + T 
Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722

Query: 104 QGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR 163
               P T  E++ + P EP     +  + + P       S+    +TT+  +     P  
Sbjct: 723 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 782

Query: 164 LAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQ 223
             PE     +S    P+    SP+E         +P  +    T+PE    A        
Sbjct: 783 STPE-----LSAEPTPKALENSPKEPG-------VPTTKTPAATKPEMTTTAKDKTTERD 830

Query: 224 QGHTPQLHTPSSSQEREQTPSEAMSQKAKETVST 257
              TP+  T +    +E   +   + ++K T +T
Sbjct: 831 LRTTPETTTAAPKMTKETATTTEKTTESKITATT 864


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 109/501 (21%), Positives = 181/501 (36%), Gaps = 76/501 (15%)

Query: 8   PAGTGSEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKE-------------CLLFL 54
           PA   + P  RVG      ++ ++ S SS+ S D    E+++                  
Sbjct: 101 PAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAP 160

Query: 55  EETIGSLDTEADSGLSTDE----SEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRT 110
            +   S D+++DS  S DE     +P  TP   +A     P P     +    +  +  +
Sbjct: 161 PKKAKSSDSDSDSS-SEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSS 219

Query: 111 VTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQ------NFRKSTTQASSHNPGEPGRL 164
            + SSSS     +     +   ++P+   +A++         RKS++   S +  E  + 
Sbjct: 220 SSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQK 279

Query: 165 APEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQ 224
            P   K     S  P  AP  P + +L       PP +A    QP +  E S  E     
Sbjct: 280 KPMKNKPGPYSSVPPPSAP--PPKKSLGTQ----PPKKAVEKQQPVESSEDSSDE----- 328

Query: 225 GHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGE 284
                  + SSS+E ++ P++A+  KA           +PPPA     + ++ +   S E
Sbjct: 329 -------SDSSSEEEKKPPTKAVVSKA---------TTKPPPAKKAAESSSDSSDSDSSE 372

Query: 285 DPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDP-------QHWLSRHTEAAPGDSGLIS 337
           D  +   P  T K     P +  KS      + P       Q  L+R  +++  +    S
Sbjct: 373 DDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEE--S 430

Query: 338 CSLQEQR--------KARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPG 389
            S +E++        K +  A   L LP  Q   G   S   S     E   +  S +  
Sbjct: 431 SSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAV 490

Query: 390 LAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAP 449
             +P   A  +A    A     +A +     +       S         K  P   P+AP
Sbjct: 491 KKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDD----SSEEEEEKLKGKGSP--RPQAP 544

Query: 450 RAN--SALTPPKPESGLTLQE 468
           +AN  SALT    ++    +E
Sbjct: 545 KANGTSALTAQNGKAAKNSEE 565


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 112/502 (22%), Positives = 182/502 (36%), Gaps = 63/502 (12%)

Query: 153  ASSHNPGEPGRLAPEPEKEQVSQSSQ-PRQAPASPQE-----AALDLD----VVLI---P 199
            ++ H  G P     +  K+   +  + P+  P  P+E     +  DL+    VV+I   P
Sbjct: 1605 SAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDALSQFDLNNYASVVIIDDHP 1664

Query: 200  PPEAFRDTQP-------------EQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEA 246
                  D Q              +Q +     E   ++    Q+    ++ E+ ++ +  
Sbjct: 1665 EVTVIEDPQSNLNDDGFTEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRSQTSK 1724

Query: 247  MSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLT---TPKPRKLPP 303
            +  +  +  +T   Q Q   A +P  A A   P +S   P S  APL    TP P     
Sbjct: 1725 LPPRFAKKQATGIQQAQSS-ASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSA 1783

Query: 304  NI-------VLKSSRSSFHSDP------QHWLSRHTEAAPGDSGLISCSLQEQRKARKEA 350
             +       VL S+ +   + P         +S    A+   + + S S      A    
Sbjct: 1784 PVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPI 1843

Query: 351  LEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGK-- 408
            L  +  P          S P  +     T A   +PAP  + PAAP   +  IPA+    
Sbjct: 1844 LASVSTPASVTILA-SASIPILASALASTSAP--TPAPAASSPAAPVITAPTIPASAPTA 1900

Query: 409  ------ALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPES 462
                  A A APAPAP P   P P   PAP    A    P+  P    + S+  PP    
Sbjct: 1901 SVPLAPASASAPAPAPTPVSAPNP-APPAPAQTQAQTHKPVQNPLQTTSQSSKQPP---P 1956

Query: 463  GLTLQESNTPGLRQ--MNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGK--GSFLDKI 518
             + L  + TP       + KS    +S   L++ L   K A P     + K  G      
Sbjct: 1957 SIRLPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQ 2016

Query: 519  SPSVLRNSRPRPASLGTGKDFAGIQVGKLADLEQEQSSKRLSYQGQSRDKLPRPPCVSVK 578
             PSV   ++P   S G+     G + G+ + LE    + +      + ++    P +S K
Sbjct: 2017 PPSVSAWNKPL-TSFGSAPSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEK 2075

Query: 579  ISPKGVPNEHRREALKKLGLLK 600
             + K    + +R+   + G +K
Sbjct: 2076 SADKIPEPKEQRQKQPRAGPIK 2097



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 86/414 (20%), Positives = 149/414 (35%), Gaps = 71/414 (17%)

Query: 73   ESEPATTPRGFRALPITQPTPRGGPEETITQQG-----RTPRTVTESSSSHPPEPQGLGL 127
            E E A+      A+P T  T     +E +   G     +TP    ++SS    E      
Sbjct: 1442 EREAASKSNEVVAVP-TNGTVNNVAQEPVNTLGDISGNKTPDLSNQNSSDQANEEWETAS 1500

Query: 128  RSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQ 187
             S  ++  R     ++ +    T      N          P K ++++ S   Q P   Q
Sbjct: 1501 ESSDFNERRERDEKKNADLNAQTVVKVGENV--------LPPKREIAKRSFSSQRPVDRQ 1552

Query: 188  EAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQ---------LHTPSSSQE 238
                +      PP      + P   R +  P   G++G             L   SS+  
Sbjct: 1553 NRRGNNG----PPKSGRNFSGPRNERRSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHH 1608

Query: 239  REQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKP 298
            +E  P+    + +K++   +   P+P P    +   A    LS  +  N     +    P
Sbjct: 1609 QEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKEKVDA----LSQFDLNNYASVVIIDDHP 1664

Query: 299  RKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQ-----EQRKARKEALEK 353
                   V++  +S+ + D             G + ++S   Q     E+R+ ++E + +
Sbjct: 1665 EVT----VIEDPQSNLNDD-------------GFTEVVSKKQQKRLQDEERRKKEEQVIQ 1707

Query: 354  LGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQA 413
            +   ++ +E G      TS + P+  + Q    A G+ Q    AQ+SA++P     LA A
Sbjct: 1708 VWNKKNANEKG---RSQTSKLPPRFAKKQ----ATGIQQ----AQSSASVPP----LASA 1752

Query: 414  PAPAPGPAQGPLPMKSPAPGN---VAASKSMPISIPKAPRANSALTPPKPESGL 464
            P P    A  P    +P P     V AS S P+         ++ + P P S L
Sbjct: 1753 PLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPL 1806



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 47/194 (24%), Positives = 78/194 (40%), Gaps = 31/194 (15%)

Query: 228  PQLHTPSSSQEREQTPSEAM-SQKAKETVSTRYTQP-----QPPPAGLPQ-NARAEDA-- 278
            P   T S+ QE   +  E+  S+K   +  + +TQ        P AG+P+  +R  D+  
Sbjct: 899  PDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKE 958

Query: 279  PLSSGEDPNSRLAPLTT---PKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGD--- 332
            P+   E+   +   + +   PKP K+        S+S     P+   +R  E        
Sbjct: 959  PIERPEEKPKKEGFIRSSEGPKPEKV------YKSKSETRWGPRPSSNRREEVNDRPVRR 1012

Query: 333  SGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSI--RPKETRAQHLSPAPGL 390
            SG I   +    K  +E        Q +++ G    K T  +  +P++T  + L P P  
Sbjct: 1013 SGPIKKPVLRDMKEERE--------QRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPP 1064

Query: 391  AQPAAPAQASAAIP 404
             QP AP Q  +  P
Sbjct: 1065 PQPPAPIQPQSVPP 1078


>gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 101/441 (22%), Positives = 155/441 (35%), Gaps = 49/441 (11%)

Query: 72  DESEPATTPRGFRALPITQPTPRG----------GPEETITQQGRTPRTVTESSSSHPPE 121
           +E   +T  +   A+ + QP+  G            E+  T Q  T  T+   S  +  E
Sbjct: 508 EEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKE 567

Query: 122 PQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR-----LAPEPEKEQVSQS 176
             GL L SG   +     + R      +  Q S+  P  P +      AP+P       S
Sbjct: 568 EGGLDLPSGRKPVAAATIVPRQAEEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVS 627

Query: 177 SQPRQAPASPQEAAL-------DLDVVLIPPPEAFRDTQPEQCREA-SLPEGPGQQGHTP 228
            Q  +    PQ++ +       D ++   P P A      +Q  E  +LP+        P
Sbjct: 628 QQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLP 687

Query: 229 QLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNS 288
              T  SS  +    +  +SQ+A+E ++        PP  L      +D  LSS   P +
Sbjct: 688 LQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL------QDTDLSSAPKPVA 741

Query: 289 RLA--------PLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAA------PGDSG 334
                       LT P+   + P + L+ +  S    P    +  ++ A      P DS 
Sbjct: 742 AATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSA 801

Query: 335 LIS-CSLQE-QRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQ 392
           +     LQ+    +  + +    L   Q E GL L + ++   P   +   LS AP    
Sbjct: 802 MTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 861

Query: 393 PAAPAQASAAIPAAGKALAQAPA-PAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRA 451
            A P    A     G  L Q  A  AP P Q   P   P P  VA  +++      AP  
Sbjct: 862 AATPVSQQAE---EGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGT 918

Query: 452 NSALTPPKPESGLTLQESNTP 472
               T  + E G  L     P
Sbjct: 919 EPVATMAQQEVGEALGPRPAP 939



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 109/473 (23%), Positives = 170/473 (35%), Gaps = 84/473 (17%)

Query: 66  DSGLSTDESEPAT-TPRGFRALP------ITQPTPRGGPEETITQQGRTPRTVTESSSSH 118
           + GL+  +   AT TP   +  P       T+ TP+ G EET +  G+      ES++  
Sbjct: 470 EEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQ------ESAAMA 523

Query: 119 PPEPQGLGLRS--GSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRL-APEPEKEQVSQ 175
            P+P   G+    G  S+         +    +    S  N  E G L  P   K   + 
Sbjct: 524 MPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAA 583

Query: 176 SSQPRQAPAS---PQEAAL-------DLDVVLIPPPEAFRDTQPEQCREA-SLPEGPGQQ 224
           +  PRQA      PQ++A+       D D+   P P A      +Q  E  +LP+     
Sbjct: 584 TIVPRQAEEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMT 643

Query: 225 GHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGE 284
              P   T  SS  +    +  +SQ+A+E ++        PP  L      +D  LSS  
Sbjct: 644 PPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL------QDTDLSSAP 697

Query: 285 DPNSRLA--------PLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAA------P 330
            P +            LT P+   + P + L+ +  S    P    +  ++ A      P
Sbjct: 698 KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLP 757

Query: 331 GDSGLI------SCSLQEQRK-------ARKEALEKLGLPQDQD-EPGLHLSKPTSSIRP 376
            DS +          L    K         ++A E L LPQD    P L L     S  P
Sbjct: 758 QDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP 817

Query: 377 KETRAQHL---SPAPGLAQP-----------------AAPAQASAAIPAAGKALAQAPAP 416
           K   A  L       GL  P                 +AP   +AA P + +A      P
Sbjct: 818 KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLP 877

Query: 417 APGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTP-PKPESGLTLQE 468
                  PLP++   P   +  + + ++ P+  +A +   P  +P + +  QE
Sbjct: 878 QDSAMTAPLPLQDTGP--TSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQE 928



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 95/435 (21%), Positives = 145/435 (33%), Gaps = 62/435 (14%)

Query: 64  EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEP- 122
           +A+  L+  +    T P   +   ++           ++QQ     T+ + S   PP P 
Sbjct: 589 QAEEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPL 648

Query: 123 QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR-----LAPEPEKEQVSQSS 177
           Q   L S    +     +++      +  Q S+  P  P +      AP+P       S 
Sbjct: 649 QDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ 708

Query: 178 QPRQAPASPQEAAL-------DLDVVLIPPPEAFRDTQPEQCREA-SLPEGPGQQGHTPQ 229
           Q  +    PQ++A+       D D+   P P A      +Q  E  +LP+        P 
Sbjct: 709 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 768

Query: 230 LHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSR 289
             T  SS  +    +  +SQ+A+E ++        PP  L      +D  LSS   P + 
Sbjct: 769 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL------QDTDLSSAPKPVAA 822

Query: 290 LA--------PLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQ 341
                      LT P+   + P + L+ +  S    P         A P           
Sbjct: 823 ATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV------AAATP----------- 865

Query: 342 EQRKARKEALEKLGLPQDQDEPG---LHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQ 398
                 ++A E L LPQD        L  + PTS   P          A     P     
Sbjct: 866 ----VSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPV 921

Query: 399 ASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRA------- 451
           A+ A    G+AL   PAP    A  P   +  A   V      P +    P A       
Sbjct: 922 ATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADS 981

Query: 452 ---NSALTPPKPESG 463
                AL+ P+P SG
Sbjct: 982 TLGMEALSLPEPASG 996



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 85/375 (22%), Positives = 134/375 (35%), Gaps = 43/375 (11%)

Query: 64   EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHP-PEP 122
            +A+ GL+  +    T P     LP+    P  GPE        TP+T+   +   P  EP
Sbjct: 869  QAEEGLTLPQDSAMTAP-----LPLQDTGPTSGPEPLAVA---TPQTLQAEAGCAPGTEP 920

Query: 123  QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQA 182
                 +           +  +   R +  + ++  P  P   A +  ++   Q +     
Sbjct: 921  VATMAQQ---------EVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGT 971

Query: 183  PASPQEAA---LDLDVVLIPPP---------EAFRDTQPEQCREASLPEGPGQQGHTPQL 230
            P + QE A   L ++ + +P P         EA      E C EA    G G +  +PQ 
Sbjct: 972  PWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQK 1031

Query: 231  HT-PSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSR 289
             T    +Q+       A     +  +      P  PPA  P+ ++A    L S       
Sbjct: 1032 ETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQAR---LLSPAREERG 1088

Query: 290  LAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKE 349
            L+  +TP+P  LP  +  ++S  S        +S      P      S    +Q     E
Sbjct: 1089 LSGKSTPEP-TLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ----PE 1143

Query: 350  ALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKA 409
             +  LG  +   E    L  P   ++P E  A+   P+  + +P  P   SA    AG A
Sbjct: 1144 PVLGLGSVEQPHEVPSVLGTPL--LQPPENLAKG-QPSTPVDRPLGP-DPSAPGTLAGAA 1199

Query: 410  LAQAPAPAPGPAQGP 424
            L     PAP   Q P
Sbjct: 1200 LPPLEPPAPCLCQDP 1214


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 76/337 (22%), Positives = 116/337 (34%), Gaps = 30/337 (8%)

Query: 172 QVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLH 231
           +V  SS P       ++  L +++V+    +A     P Q R+     G G  G TP   
Sbjct: 386 EVVGSSMPLIGDHQDEDKQLIVELVVNKMAQAL----PRQ-RQRDASPGRGSHGQTP--- 437

Query: 232 TPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLA 291
           +P +     QT  +     A++    +   PQP P    Q    +  P   G+   S L 
Sbjct: 438 SPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLG 497

Query: 292 PLT-TPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEA 350
           P   +P P++LP         +S  + P     R +    G  G    +   +  A    
Sbjct: 498 PPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAA---RPPASPSP 554

Query: 351 LEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPA---PGLAQPAAPAQASAAIPAAG 407
             + G PQ   +  +    P  +        Q   P    PG A P   A  +  +P  G
Sbjct: 555 QRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTG 614

Query: 408 KALAQAPAPA-PGPAQGPLPMKS-------PAPGNVAASKSMPISIPKAPRANSALTPPK 459
               Q P P+ PGPA  P P  +       P P   AA       + K+    +A   P+
Sbjct: 615 PPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPE 674

Query: 460 PESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLS 496
           P           P L Q   K+ T+       +S  S
Sbjct: 675 P-------APPRPSLSQDEVKAETIRSLRKSFASLFS 704



 Score = 36.2 bits (82), Expect = 0.089
 Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 14/149 (9%)

Query: 159 GEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLP 218
           G P +  P P+ +Q      P      PQ           P  +A   TQ +  +   + 
Sbjct: 478 GPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537

Query: 219 EGPGQQGHTPQLHTPSS-SQEREQTPSEAMSQKAKETVSTRYTQPQPPPA-GLPQNARAE 276
            GPG     P    P+S S +R+  P +A  Q       T  + P PP A G P   +  
Sbjct: 538 GGPGA---PPAARPPASPSPQRQAGPPQATRQ-------TSVSGPAPPKASGAPPGGQQR 587

Query: 277 DAPLSSGEDP--NSRLAPLTTPKPRKLPP 303
             P      P   +R A    P PR  PP
Sbjct: 588 QGPPQKPPGPAGPTRQASQAGPVPRTGPP 616



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 3/46 (6%)

Query: 412 QAPAPAPGPAQGPLPMKSPAPGNVAASKS---MPISIPKAPRANSA 454
           Q P P P P     P  +P PG   A +S    P + P AP   S+
Sbjct: 26  QRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSS 71


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 120/505 (23%), Positives = 179/505 (35%), Gaps = 96/505 (19%)

Query: 76  PATTPRGFRALPITQPTPRG------GPEETITQQGRTP-----------RTVTESSSSH 118
           P ++P   RA   T+P P G        EET+ +   T            R  T   +  
Sbjct: 104 PVSSPG--RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 161

Query: 119 PPEPQGLGLRSGS----YSLPRNIHIAR----SQNFRKSTTQASSHNPGEPGRLA----- 165
            P P  +  RS +      LPR    AR    ++  RKS + AS H+  EP   A     
Sbjct: 162 TPSP-AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 220

Query: 166 -----PEPEKEQVSQSSQPRQAPASPQEAALDLDVVLI----PPPEAFRDTQPEQCREAS 216
                  P    +S S+ P  +PA    +A            P P+  +  +P Q     
Sbjct: 221 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT--- 277

Query: 217 LPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAE 276
               P ++   P L   SSS     +PS   S  A  ++ T  + P  PP+    +  + 
Sbjct: 278 ----PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 333

Query: 277 DAPLSSGEDPNSRLAPLTTPKPRKLPPNIVL---KSSRSSFHSDPQHWLSRHTEAAPGDS 333
               +    P+  L+PL TP P+  PP + L   ++  S   S P   L+  +  AP   
Sbjct: 334 TLQATHSFLPSPPLSPLATPPPQA-PPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392

Query: 334 G--LISCSLQEQRKARKEA---------LEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQ 382
              L+            +A         +     P  Q  P L  + P   + P    + 
Sbjct: 393 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL--AAPPLQVPPSPPASP 450

Query: 383 HLSPA---PGLAQP---AAPAQASAAIPAAGKALAQAPA------PAPGPAQGPL----- 425
            +SP+   P  A P   A P Q +   P A  ALA  P       PA  P Q P      
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510

Query: 426 ----PMKSPAPGNVAASKSMPISIPKAPRANSAL----TPPKP-----ESGLTLQESNTP 472
               P+ +P P       +  + +P +P A+  L     PP P      SG  L  +  P
Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 570

Query: 473 GLRQMNFKSNTLERSGVGLSSYLST 497
           G      +S +   SG  L+ + S+
Sbjct: 571 GPPPPPSRSPSSTLSGPDLAGHSSS 595



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 108/429 (25%), Positives = 148/429 (34%), Gaps = 58/429 (13%)

Query: 71  TDESEPATTPRGFRALPI--TQPTPRGGPEET--------ITQQG---RTPRTVTESSSS 117
           T  S P  + RG RA P   T P P   P           + Q+G       TV    ++
Sbjct: 80  TRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 139

Query: 118 HPPEPQGLGL---RSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVS 174
             P+   L     R  S   P     A ++  R + T+     P    R  P  E  + S
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 199

Query: 175 QSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPS 234
            SS    +   P  AA          P A    Q    R  S    P     +P    PS
Sbjct: 200 VSSASEHSTTEPSPAARRR-------PSAGGGLQRPASRSLSSSATPLS---SPARSGPS 249

Query: 235 SSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLT 294
           + +   + P+     K K   + R  Q  PP     ++A     PLSS        +PL 
Sbjct: 250 A-RGTPRAPAHPSQPKPKGLQALRPPQVTPPR----KDAAPALGPLSS--------SPLA 296

Query: 295 TPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGD------SGLISCSLQEQRKARK 348
           TP P   PP+     S  +  S P    S+ T +          S L S  L        
Sbjct: 297 TPSP-SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355

Query: 349 EALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQ-----HLSPAPGLAQPAAPAQASAAI 403
           +A   L LP  Q  P    S P S +     +A      HL  AP    P+ P QA  + 
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415

Query: 404 PAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESG 463
           PA+      +P+  P P+Q P  + +P    +    S P S P +P A      P P + 
Sbjct: 416 PASPPV---SPSATP-PSQAPPSLAAPP---LQVPPSPPASPPMSPSATPPPQAPPPLAA 468

Query: 464 LTLQESNTP 472
             LQ +  P
Sbjct: 469 PPLQLAKPP 477



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 103/432 (23%), Positives = 144/432 (33%), Gaps = 67/432 (15%)

Query: 59  GSLDTEADSGLS---TDESEPATTPRGFRALPI-----TQPTPRG-----GPEETITQQG 105
           G L   A   LS   T  S PA +    R  P      +QP P+G      P+ T  ++ 
Sbjct: 223 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 282

Query: 106 RTPRTVTESSS-------SHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQAS-SHN 157
             P     SSS       S PP P          S P       + +    T QA+ S  
Sbjct: 283 AAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 342

Query: 158 PGEP-GRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREAS 216
           P  P   LA  P +   + +  P QAP SP  A+  L  +  P P+A             
Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPP-ASPPLSPLATPSPQA------PNALAVH 395

Query: 217 LPEGPGQQGHTPQLHTPSSSQEREQ-TPSEAMSQKAKETVSTRYTQ-PQPPPAGLPQNAR 274
           L + P     +P +  P S       +PS     +A  +++    Q P  PPA  P +  
Sbjct: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 455

Query: 275 AEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSG 334
           A   P +    P     PL   KP    P  +      +  S P  +        PG + 
Sbjct: 456 ATPPPQAP---PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF--------PGQAP 504

Query: 335 LI-SCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQP 393
              S SL          +  L  P  Q  P L  + P   + P    +      P L  P
Sbjct: 505 FSPSASLP---------MSPLATPPPQAPPVL--AAPLLQVPPSPPAS------PTLQAP 547

Query: 394 AAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPK------ 447
             P         +G  L  A AP P P     P  + +  ++A   S   S P+      
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 607

Query: 448 -APRANSALTPP 458
             P   +A +PP
Sbjct: 608 SGPEGGAAASPP 619



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 95/403 (23%), Positives = 142/403 (35%), Gaps = 47/403 (11%)

Query: 54  LEETIGSLDTEADSGLSTD--ESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTV 111
           L+ T   L +   S L+T   ++ PA      +A P    +P   P  T + Q      V
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394

Query: 112 --TESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPE 169
              ++  S PP P         +S P +  ++ S       +QA       P ++ P P 
Sbjct: 395 HLLQAPFSPPPSPPV----QAPFSPPASPPVSPSAT---PPSQAPPSLAAPPLQVPPSPP 447

Query: 170 KEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEA--FRDTQPEQCREASLPEGPGQQGHT 227
                  S      A P  AA  L +   PPP+A     T P Q   +     PGQ   +
Sbjct: 448 ASPPMSPSATPPPQAPPPLAAPPLQLAK-PPPQAPPALATPPLQALPSPPASFPGQAPFS 506

Query: 228 PQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPN 287
           P    P S       P      +A   ++    Q  P P   P   +A   P + G D +
Sbjct: 507 PSASLPMS-------PLATPPPQAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGPDTS 558

Query: 288 SR-------LAPLTTPKPRKLPPNIV----LKSSRSSFHSDPQHWLSRHT-------EAA 329
                    LAP   P P + P + +    L    SS  S P+      +        + 
Sbjct: 559 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 618

Query: 330 PGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSS---IRPKETRA-QHLS 385
           P D+ L +C      +     L   G P     P    + P S+       ET   +  +
Sbjct: 619 PPDAELAACHPAAWSRGPAPPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEGPESAT 677

Query: 386 PAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQ-GPLPM 427
           PAPG   P  P+  ++   AA  A A A + +P  A+ G LP+
Sbjct: 678 PAPGALDP-GPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 719


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 107/395 (27%), Positives = 155/395 (39%), Gaps = 56/395 (14%)

Query: 160 EPGRLAPEPEKEQVS-QSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLP 218
           +P +  P PE +++   S++P+  PA   E    L  VL P         P +      P
Sbjct: 104 DPVKSPPLPEHQKIPCNSAEPKSIPALSMETQ-KLGSVLSPESPKPTPLTPLE------P 156

Query: 219 EGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDA 278
           + PG    +P+L TP  S E  +  S +  +  K        +  P P+  PQ    + A
Sbjct: 157 QKPGSVV-SPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQ----KPA 211

Query: 279 PLSSGEDPNSRLAPLTTPKPRKLP--PNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLI 336
           P+S    P S  A L+ PKP+K    P  +   S SS    P+   S    A+P   G  
Sbjct: 212 PVS----PESVKATLSNPKPQKQSHFPETLGPPSASS----PE---SPVLAASPEPWGPS 260

Query: 337 SCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAP 396
             +  E RK+ +    +   P   + P     KP  ++ P E R    + +PG  +P  P
Sbjct: 261 PAASPESRKSARTTSPEPRKPSPSESP--EPWKPFPAVSP-EPRRPAPAVSPGSWKPGPP 317

Query: 397 AQA------SAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPR 450
                     +A     K    AP+ +PGP + P+P  SP P     S S       +  
Sbjct: 318 GSPRPWKSNPSASSGPWKPAKPAPSVSPGPWK-PIPSVSPGPWKPTPSVSSASWKSSSVS 376

Query: 451 ANSALTPP-KPE---SGLTLQESNTPGLRQMNFK-----SNTLERSGVGLSSYLSTEKDA 501
            +S  +PP  PE   SG        P L   ++K     S  L + G  LS  +      
Sbjct: 377 PSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEI-----R 431

Query: 502 SPKTSTSLGKGS---FLDKISPSVLRNSRPRPASL 533
           SP  S  L K S    L K+SP   + S   PASL
Sbjct: 432 SPAGSPELRKPSGSPDLWKLSPDQRKTS---PASL 463



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 19/166 (11%)

Query: 309 SSRSSFHSDPQHWLSRHTEAAPG----DSGLISCSLQEQRKARKEALE--KLGLPQDQDE 362
           +S   ++  P++ L++ T+        +   I C+  E +     ++E  KLG     + 
Sbjct: 86  ASPDKWNDKPKNQLNKETDPVKSPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPES 145

Query: 363 PG------LHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAP 416
           P       L   KP S + P+    Q   P+P   +P+ PA  S+  P     + ++   
Sbjct: 146 PKPTPLTPLEPQKPGSVVSPE---LQTPLPSP---EPSKPASVSSPEPPKSVPVCESQKL 199

Query: 417 APGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPES 462
           AP P+  P      +P +V A+ S P    K       L PP   S
Sbjct: 200 APVPSPEPQKPAPVSPESVKATLSNP-KPQKQSHFPETLGPPSASS 244


>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 100/441 (22%), Positives = 155/441 (35%), Gaps = 49/441 (11%)

Query: 72  DESEPATTPRGFRALPITQPTPRG----------GPEETITQQGRTPRTVTESSSSHPPE 121
           +E   +T  +   A+ + QP+  G            E+  T Q  T  T+   S  +  E
Sbjct: 508 EEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKE 567

Query: 122 PQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR-----LAPEPEKEQVSQS 176
             GL L SG   +     + R      +  Q S+  P  P +      AP+P       S
Sbjct: 568 EGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVS 627

Query: 177 SQPRQAPASPQEAAL-------DLDVVLIPPPEAFRDTQPEQCREA-SLPEGPGQQGHTP 228
            Q  +    PQ++ +       D ++   P P A      +Q  E  +LP+        P
Sbjct: 628 QQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLP 687

Query: 229 QLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNS 288
              T  SS  +    +  +SQ+A+E ++        PP  L      +D  LSS   P +
Sbjct: 688 LQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL------QDTDLSSAPKPVA 741

Query: 289 RLA--------PLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAA------PGDSG 334
                       LT P+   + P + L+ +  S    P    +  ++ A      P DS 
Sbjct: 742 AATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSA 801

Query: 335 LIS-CSLQE-QRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQ 392
           +     LQ+    +  + +    +   Q E GL L + ++   P   +   LS AP    
Sbjct: 802 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 861

Query: 393 PAAPAQASAAIPAAGKALAQAPA-PAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRA 451
            A P    A     G  L Q  A  AP P Q   P   P P  VA  +++      AP  
Sbjct: 862 AATPVSQQAE---EGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGT 918

Query: 452 NSALTPPKPESGLTLQESNTP 472
               T  + E G  L     P
Sbjct: 919 EPVATMAQQEVGEALGPRPAP 939



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 108/473 (22%), Positives = 170/473 (35%), Gaps = 84/473 (17%)

Query: 66  DSGLSTDESEPAT-TPRGFRALP------ITQPTPRGGPEETITQQGRTPRTVTESSSSH 118
           + GL+  +   AT TP   +  P       T+ TP+ G EET +  G+      ES++  
Sbjct: 470 EEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQ------ESAAMA 523

Query: 119 PPEPQGLGLRS--GSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRL-APEPEKEQVSQ 175
            P+P   G+    G  S+         +    +    S  N  E G L  P   K   + 
Sbjct: 524 MPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAA 583

Query: 176 SSQPRQAPAS---PQEAAL-------DLDVVLIPPPEAFRDTQPEQCREA-SLPEGPGQQ 224
           +  PRQA      PQ++A+       D D+   P P A      +Q  E  +LP+     
Sbjct: 584 TIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMT 643

Query: 225 GHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGE 284
              P   T  SS  +    +  +SQ+A+E ++        PP  L      +D  LSS  
Sbjct: 644 PPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL------QDTDLSSAP 697

Query: 285 DPNSRLA--------PLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAA------P 330
            P +            LT P+   + P + L+ +  S    P    +  ++ A      P
Sbjct: 698 KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLP 757

Query: 331 GDSGLI------SCSLQEQRK-------ARKEALEKLGLPQDQD-EPGLHLSKPTSSIRP 376
            DS +          L    K         ++A E L LPQD    P L L     S  P
Sbjct: 758 QDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP 817

Query: 377 KETRAQHL---SPAPGLAQP-----------------AAPAQASAAIPAAGKALAQAPAP 416
           K   A  +       GL  P                 +AP   +AA P + +A      P
Sbjct: 818 KPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLP 877

Query: 417 APGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTP-PKPESGLTLQE 468
                  PLP++   P   +  + + ++ P+  +A +   P  +P + +  QE
Sbjct: 878 QDSAMTAPLPLQDTGP--TSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQE 928



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 95/435 (21%), Positives = 144/435 (33%), Gaps = 62/435 (14%)

Query: 64  EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEP- 122
           +A   L+  +    T P   +   ++           ++QQ     T+ + S   PP P 
Sbjct: 589 QAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPL 648

Query: 123 QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR-----LAPEPEKEQVSQSS 177
           Q   L S    +     +++      +  Q S+  P  P +      AP+P       S 
Sbjct: 649 QDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ 708

Query: 178 QPRQAPASPQEAAL-------DLDVVLIPPPEAFRDTQPEQCREA-SLPEGPGQQGHTPQ 229
           Q  +    PQ++A+       D D+   P P A      +Q  E  +LP+        P 
Sbjct: 709 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 768

Query: 230 LHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSR 289
             T  SS  +    +  +SQ+A+E ++        PP  L      +D  LSS   P + 
Sbjct: 769 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL------QDTDLSSAPKPVAA 822

Query: 290 LA--------PLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQ 341
                      LT P+   + P + L+ +  S    P         A P           
Sbjct: 823 ATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV------AAATP----------- 865

Query: 342 EQRKARKEALEKLGLPQDQDEPG---LHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQ 398
                 ++A E L LPQD        L  + PTS   P          A     P     
Sbjct: 866 ----VSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPV 921

Query: 399 ASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRA------- 451
           A+ A    G+AL   PAP    A  P   +  A   V      P +    P A       
Sbjct: 922 ATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADS 981

Query: 452 ---NSALTPPKPESG 463
                AL+ P+P SG
Sbjct: 982 TLGMEALSLPEPASG 996



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 85/375 (22%), Positives = 134/375 (35%), Gaps = 43/375 (11%)

Query: 64   EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHP-PEP 122
            +A+ GL+  +    T P     LP+    P  GPE        TP+T+   +   P  EP
Sbjct: 869  QAEEGLTLPQDSAMTAP-----LPLQDTGPTSGPEPLAVA---TPQTLQAEAGCAPGTEP 920

Query: 123  QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQA 182
                 +           +  +   R +  + ++  P  P   A +  ++   Q +     
Sbjct: 921  VATMAQQ---------EVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGT 971

Query: 183  PASPQEAA---LDLDVVLIPPP---------EAFRDTQPEQCREASLPEGPGQQGHTPQL 230
            P + QE A   L ++ + +P P         EA      E C EA    G G +  +PQ 
Sbjct: 972  PWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQK 1031

Query: 231  HT-PSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSR 289
             T    +Q+       A     +  +      P  PPA  P+ ++A    L S       
Sbjct: 1032 ETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQAR---LLSPAREERG 1088

Query: 290  LAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKE 349
            L+  +TP+P  LP  +  ++S  S        +S      P      S    +Q     E
Sbjct: 1089 LSGKSTPEP-TLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ----PE 1143

Query: 350  ALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKA 409
             +  LG  +   E    L  P   ++P E  A+   P+  + +P  P   SA    AG A
Sbjct: 1144 PVLGLGSVEQPHEVPSVLGTPL--LQPPENLAKG-QPSTPVDRPLGP-DPSAPGTLAGAA 1199

Query: 410  LAQAPAPAPGPAQGP 424
            L     PAP   Q P
Sbjct: 1200 LPPLEPPAPCLCQDP 1214


>gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 100/441 (22%), Positives = 155/441 (35%), Gaps = 49/441 (11%)

Query: 72  DESEPATTPRGFRALPITQPTPRG----------GPEETITQQGRTPRTVTESSSSHPPE 121
           +E   +T  +   A+ + QP+  G            E+  T Q  T  T+   S  +  E
Sbjct: 508 EEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKE 567

Query: 122 PQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR-----LAPEPEKEQVSQS 176
             GL L SG   +     + R      +  Q S+  P  P +      AP+P       S
Sbjct: 568 EGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVS 627

Query: 177 SQPRQAPASPQEAAL-------DLDVVLIPPPEAFRDTQPEQCREA-SLPEGPGQQGHTP 228
            Q  +    PQ++ +       D ++   P P A      +Q  E  +LP+        P
Sbjct: 628 QQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLP 687

Query: 229 QLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNS 288
              T  SS  +    +  +SQ+A+E ++        PP  L      +D  LSS   P +
Sbjct: 688 LQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL------QDTDLSSAPKPVA 741

Query: 289 RLA--------PLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAA------PGDSG 334
                       LT P+   + P + L+ +  S    P    +  ++ A      P DS 
Sbjct: 742 AATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSA 801

Query: 335 LIS-CSLQE-QRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQ 392
           +     LQ+    +  + +    +   Q E GL L + ++   P   +   LS AP    
Sbjct: 802 MTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVA 861

Query: 393 PAAPAQASAAIPAAGKALAQAPA-PAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRA 451
            A P    A     G  L Q  A  AP P Q   P   P P  VA  +++      AP  
Sbjct: 862 AATPVSQQAE---EGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGT 918

Query: 452 NSALTPPKPESGLTLQESNTP 472
               T  + E G  L     P
Sbjct: 919 EPVATMAQQEVGEALGPRPAP 939



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 108/473 (22%), Positives = 170/473 (35%), Gaps = 84/473 (17%)

Query: 66  DSGLSTDESEPAT-TPRGFRALP------ITQPTPRGGPEETITQQGRTPRTVTESSSSH 118
           + GL+  +   AT TP   +  P       T+ TP+ G EET +  G+      ES++  
Sbjct: 470 EEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQ------ESAAMA 523

Query: 119 PPEPQGLGLRS--GSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRL-APEPEKEQVSQ 175
            P+P   G+    G  S+         +    +    S  N  E G L  P   K   + 
Sbjct: 524 MPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAA 583

Query: 176 SSQPRQAPAS---PQEAAL-------DLDVVLIPPPEAFRDTQPEQCREA-SLPEGPGQQ 224
           +  PRQA      PQ++A+       D D+   P P A      +Q  E  +LP+     
Sbjct: 584 TIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMT 643

Query: 225 GHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGE 284
              P   T  SS  +    +  +SQ+A+E ++        PP  L      +D  LSS  
Sbjct: 644 PPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL------QDTDLSSAP 697

Query: 285 DPNSRLA--------PLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAA------P 330
            P +            LT P+   + P + L+ +  S    P    +  ++ A      P
Sbjct: 698 KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLP 757

Query: 331 GDSGLI------SCSLQEQRK-------ARKEALEKLGLPQDQD-EPGLHLSKPTSSIRP 376
            DS +          L    K         ++A E L LPQD    P L L     S  P
Sbjct: 758 QDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP 817

Query: 377 KETRAQHL---SPAPGLAQP-----------------AAPAQASAAIPAAGKALAQAPAP 416
           K   A  +       GL  P                 +AP   +AA P + +A      P
Sbjct: 818 KPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLP 877

Query: 417 APGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTP-PKPESGLTLQE 468
                  PLP++   P   +  + + ++ P+  +A +   P  +P + +  QE
Sbjct: 878 QDSAMTAPLPLQDTGP--TSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQE 928



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 95/435 (21%), Positives = 144/435 (33%), Gaps = 62/435 (14%)

Query: 64  EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEP- 122
           +A   L+  +    T P   +   ++           ++QQ     T+ + S   PP P 
Sbjct: 589 QAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPL 648

Query: 123 QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGR-----LAPEPEKEQVSQSS 177
           Q   L S    +     +++      +  Q S+  P  P +      AP+P       S 
Sbjct: 649 QDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQ 708

Query: 178 QPRQAPASPQEAAL-------DLDVVLIPPPEAFRDTQPEQCREA-SLPEGPGQQGHTPQ 229
           Q  +    PQ++A+       D D+   P P A      +Q  E  +LP+        P 
Sbjct: 709 QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 768

Query: 230 LHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSR 289
             T  SS  +    +  +SQ+A+E ++        PP  L      +D  LSS   P + 
Sbjct: 769 QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPL------QDTDLSSAPKPVAA 822

Query: 290 LA--------PLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQ 341
                      LT P+   + P + L+ +  S    P         A P           
Sbjct: 823 ATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPV------AAATP----------- 865

Query: 342 EQRKARKEALEKLGLPQDQDEPG---LHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQ 398
                 ++A E L LPQD        L  + PTS   P          A     P     
Sbjct: 866 ----VSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPV 921

Query: 399 ASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRA------- 451
           A+ A    G+AL   PAP    A  P   +  A   V      P +    P A       
Sbjct: 922 ATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADS 981

Query: 452 ---NSALTPPKPESG 463
                AL+ P+P SG
Sbjct: 982 TLGMEALSLPEPASG 996



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 85/375 (22%), Positives = 134/375 (35%), Gaps = 43/375 (11%)

Query: 64   EADSGLSTDESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHP-PEP 122
            +A+ GL+  +    T P     LP+    P  GPE        TP+T+   +   P  EP
Sbjct: 869  QAEEGLTLPQDSAMTAP-----LPLQDTGPTSGPEPLAVA---TPQTLQAEAGCAPGTEP 920

Query: 123  QGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQA 182
                 +           +  +   R +  + ++  P  P   A +  ++   Q +     
Sbjct: 921  VATMAQQ---------EVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGT 971

Query: 183  PASPQEAA---LDLDVVLIPPP---------EAFRDTQPEQCREASLPEGPGQQGHTPQL 230
            P + QE A   L ++ + +P P         EA      E C EA    G G +  +PQ 
Sbjct: 972  PWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQK 1031

Query: 231  HT-PSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSR 289
             T    +Q+       A     +  +      P  PPA  P+ ++A    L S       
Sbjct: 1032 ETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQAR---LLSPAREERG 1088

Query: 290  LAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKE 349
            L+  +TP+P  LP  +  ++S  S        +S      P      S    +Q     E
Sbjct: 1089 LSGKSTPEP-TLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQ----PE 1143

Query: 350  ALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKA 409
             +  LG  +   E    L  P   ++P E  A+   P+  + +P  P   SA    AG A
Sbjct: 1144 PVLGLGSVEQPHEVPSVLGTPL--LQPPENLAKG-QPSTPVDRPLGP-DPSAPGTLAGAA 1199

Query: 410  LAQAPAPAPGPAQGP 424
            L     PAP   Q P
Sbjct: 1200 LPPLEPPAPCLCQDP 1214


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 106/461 (22%), Positives = 163/461 (35%), Gaps = 64/461 (13%)

Query: 84  RALPITQPTP-RGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIAR 142
           R  P  +P P   GP ++++       T    ++   P   G   R  S SL  +     
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250

Query: 143 SQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQ--PRQAPASPQEAALDLDVVLIPP 200
           S      + + +   P  P +  P+P+  Q  +  Q  P +  A+P    L    +  P 
Sbjct: 251 SPARSGPSARGTPRAPAHPSQ--PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308

Query: 201 PEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYT 260
           P A   +Q       +LP  P     T QL TP         P    S  A  ++ T  +
Sbjct: 309 PSAALQSQAPP----TLPATPHSSSLTCQLATP--------LPLAPPSPSAPPSLQTLPS 356

Query: 261 QPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVL---KSSRSSFHSD 317
            P  PP+    +  +     +    P+  L+PL TP P+  PP + L   ++  S   S 
Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA-PPALALPPLQAPPSPPASP 415

Query: 318 PQHWLSRHTEAAPGDSG--LISCSLQEQRKARKEA---------LEKLGLPQDQDEPGLH 366
           P   L+  +  AP      L+            +A         +     P  Q  P L 
Sbjct: 416 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL- 474

Query: 367 LSKPTSSIRPKETRAQHLSPA---PGLAQP---AAPAQASAAIPAAGKALAQAPA----- 415
            + P   + P    +  +SP+   P  A P   A P Q +   P A  ALA  P      
Sbjct: 475 -AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPS 533

Query: 416 -PAPGPAQGPL---------PMKSPAPGNVAASKSMPISIPKAPRANSAL----TPPKP- 460
            PA  P Q P          P+ +P P       +  + +P +P A+  L     PP P 
Sbjct: 534 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 593

Query: 461 ----ESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLST 497
                SG  L  +  PG      +S +   SG  L+ + S+
Sbjct: 594 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 110/441 (24%), Positives = 156/441 (35%), Gaps = 81/441 (18%)

Query: 76  PATTPRGFRALPITQPTPRG------GPEETITQQGRTP-----------RTVTESSSSH 118
           P ++P   RA   T+P P G        EET+ +   T            R  T   +  
Sbjct: 113 PVSSPG--RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170

Query: 119 PPEPQGLGLRSGS----YSLPRNIHIAR----SQNFRKSTTQASSHNPGEPGRLA----- 165
            P P  +  RS +      LPR    AR    ++  RKS + AS H+  EP   A     
Sbjct: 171 TPSP-AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 229

Query: 166 -----PEPEKEQVSQSSQPRQAPASPQEAALDLDVVLI----PPPEAFRDTQPEQCREAS 216
                  P    +S S+ P  +PA    +A            P P+  +  +P Q     
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT--- 286

Query: 217 LPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAE 276
               P ++   P L   SSS     +PS A+  +A  T+      P  P +       A 
Sbjct: 287 ----PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTL------PATPHSSSLTCQLAT 336

Query: 277 DAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLI 336
             PL+    P++  +  T P P   PP+    S            L   T  A   S L 
Sbjct: 337 PLPLAP-PSPSAPPSLQTLPSPPATPPSQATTS------------LGSPTLQAT-HSFLP 382

Query: 337 SCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQ-----HLSPAPGLA 391
           S  L        +A   L LP  Q  P    S P S +     +A      HL  AP   
Sbjct: 383 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 442

Query: 392 QPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRA 451
            P+ P QA  + PA+      +P+  P P+Q P  + +P    +    S P S P +P A
Sbjct: 443 PPSPPVQAPFSPPASPPV---SPSATP-PSQAPPSLAAPP---LQVPPSPPASPPMSPSA 495

Query: 452 NSALTPPKPESGLTLQESNTP 472
                 P P +   LQ +  P
Sbjct: 496 TPPPQAPPPLAAPPLQLAKPP 516



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 98/409 (23%), Positives = 137/409 (33%), Gaps = 55/409 (13%)

Query: 64  EADSGLSTDESEPATTPRGFRALPITQPT--PRGGPEETITQQGRTPRTVTESSSSHPPE 121
           +A   L    S P  TP    AL    P   P      ++T Q  TP  +   S S PP 
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPS 350

Query: 122 PQGLGLRSGSYSLPRNIHIARSQNFRKSTTQAS-SHNPGEP-GRLAPEPEKEQVSQSSQP 179
            Q L       S P       + +    T QA+ S  P  P   LA  P +   + +  P
Sbjct: 351 LQTLP------SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 404

Query: 180 RQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQER 239
            QAP SP  A+  L  +  P P+A             L + P     +P +  P S    
Sbjct: 405 LQAPPSPP-ASPPLSPLATPSPQA------PNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457

Query: 240 EQ-TPSEAMSQKAKETVSTRYTQ-PQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPK 297
              +PS     +A  +++    Q P  PPA  P +  A   P +    P     PL   K
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP---PPLAAPPLQLAK 514

Query: 298 PRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLI-SCSLQEQRKARKEALEKLGL 356
           P    P  +      +  S P  +        PG +    S SL          +  L  
Sbjct: 515 PPPQAPPALATPPLQALPSPPASF--------PGQAPFSPSASLP---------MSPLAT 557

Query: 357 PQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAP 416
           P  Q  P L  + P   + P    +      P L  P  P         +G  L  A AP
Sbjct: 558 PPPQAPPVL--AAPLLQVPPSPPAS------PTLQAPRRPPTPGPDTSVSGPRLTLALAP 609

Query: 417 APGPAQGPLPMKSPAPGNVAASKSMPISIPK-------APRANSALTPP 458
            P P     P  + +  ++A   S   S P+        P   +A +PP
Sbjct: 610 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 658



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 92/407 (22%), Positives = 136/407 (33%), Gaps = 45/407 (11%)

Query: 82  GFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSYSLP-RNIHI 140
           G     I +  PR GP  +     R P +   +S      P       G  S P R    
Sbjct: 64  GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123

Query: 141 ARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVS-----QSSQPRQAPASPQEA----AL 191
            R     +   + S+      G+    P++  +S      +S P     SP  A    A 
Sbjct: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183

Query: 192 DLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHT---PSSSQEREQTPSEAMS 248
             +V L  P  + R   P         EGP +   +   H+   PS +  R  +    + 
Sbjct: 184 GTEVGLPRPAPSARPRPP--------TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235

Query: 249 QKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRL----APLTTPKPRKLPPN 304
           + A  ++S+  T    P    P       AP    +     L     P  TP  +   P 
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295

Query: 305 IVLKSSRSSFHSDPQHWLSRH---TEAAPGDSGLISCS------LQEQRKARKEALEKLG 355
           +   SS       P   L      T  A   S  ++C       L     +   +L+ L 
Sbjct: 296 LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP 355

Query: 356 LPQDQDEPGLHLSKPTSSIRPKETRAQH-LSPAPGLAQPAA-PAQASAAIPAAGKALAQA 413
            P     P    S+ T+S+     +A H   P+P L+  A  P QA  A+  A   L   
Sbjct: 356 SP-----PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL--ALPPLQAP 408

Query: 414 PAPAPGPAQGPLPMKSPAPGNVAASKSM--PISIPKAPRANSALTPP 458
           P+P   P   PL   SP   N  A   +  P S P +P   +  +PP
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 455



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 95/403 (23%), Positives = 142/403 (35%), Gaps = 47/403 (11%)

Query: 54  LEETIGSLDTEADSGLSTD--ESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTV 111
           L+ T   L +   S L+T   ++ PA      +A P    +P   P  T + Q      V
Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433

Query: 112 --TESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPE 169
              ++  S PP P         +S P +  ++ S       +QA       P ++ P P 
Sbjct: 434 HLLQAPFSPPPSPPV----QAPFSPPASPPVSPSAT---PPSQAPPSLAAPPLQVPPSPP 486

Query: 170 KEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEA--FRDTQPEQCREASLPEGPGQQGHT 227
                  S      A P  AA  L +   PPP+A     T P Q   +     PGQ   +
Sbjct: 487 ASPPMSPSATPPPQAPPPLAAPPLQLAK-PPPQAPPALATPPLQALPSPPASFPGQAPFS 545

Query: 228 PQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPN 287
           P    P S       P      +A   ++    Q  P P   P   +A   P + G D +
Sbjct: 546 PSASLPMS-------PLATPPPQAPPVLAAPLLQVPPSPPASP-TLQAPRRPPTPGPDTS 597

Query: 288 SR-------LAPLTTPKPRKLPPNIV----LKSSRSSFHSDPQHWLSRHT-------EAA 329
                    LAP   P P + P + +    L    SS  S P+      +        + 
Sbjct: 598 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 657

Query: 330 PGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSS---IRPKETRA-QHLS 385
           P D+ L +C      +     L   G P     P    + P S+       ET   +  +
Sbjct: 658 PPDAELAACHPAAWSRGPAPPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEGPESAT 716

Query: 386 PAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQ-GPLPM 427
           PAPG   P  P+  ++   AA  A A A + +P  A+ G LP+
Sbjct: 717 PAPGALDP-GPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 758


>gi|11641239 hypothetical protein LOC53838 [Homo sapiens]
          Length = 449

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 71/291 (24%), Positives = 99/291 (34%), Gaps = 21/291 (7%)

Query: 13  SEPVTRVGSCDSMMSSTSTRSGSSDSSYDFLSTEEKECLLFLEETIGSLDTEADSGLSTD 72
           SEP T  G+ D + S   T   SS ++    +      +        S  T A S  +  
Sbjct: 90  SEPATSGGAADGVTSIAPTAVASSTTAASITTAASSMTVA------SSAPTTAASSTTVA 143

Query: 73  ESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGLRSGSY 132
              P T      A   T P     P  T T  GRTP T   +++ HP     L     S 
Sbjct: 144 SIAPTTAASSMTAASST-PMTLALPAPTSTSTGRTPST---TATGHPSLSTALAQVPKSS 199

Query: 133 SLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALD 192
           +LPR   +A      ++ T A++ N   P    P P K   S ++     P  PQ A   
Sbjct: 200 ALPRTATLATLAT--RAQTVATTANTSSPMSTRPSPSKHMPSDTAASPVPPMRPQ-AQGP 256

Query: 193 LDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAK 252
           +  V +  P      +       + PE       TP + T + +Q RE T S        
Sbjct: 257 ISQVSVDQPVVNTTNKSTPMPSNTTPE----PAPTPTVVTTTKAQAREPTASPVPVPHTS 312

Query: 253 ETVSTRYTQPQPPPAGLPQNARAEDAPLSSG-EDPNSRLAP---LTTPKPR 299
                    P   P+ +P   RA     S   E   +   P    T P PR
Sbjct: 313 PIPEMEAMSPTTQPSPMPYTQRAAGPGTSQAPEQVETEATPGTDSTGPTPR 363


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 104/429 (24%), Positives = 161/429 (37%), Gaps = 90/429 (20%)

Query: 113 ESSSSHPPEPQGLGL---RSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPE 169
           ES +S PPE   L        +  LP  +H++R         ++    P E   L+P PE
Sbjct: 455 ESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLE------ESPLSPPPEESPLSPPPE 508

Query: 170 KE-----QVSQSSQPRQAPASPQEAALDLDVVLIPPPEA------FRDT----QPEQCRE 214
                  + S  S P ++P SP      L+  L PPPEA      F ++     PE+   
Sbjct: 509 SSPFSPLEESPLSPPEESPPSPA-----LETPLSPPPEASPLSPPFEESPLSPPPEELPT 563

Query: 215 ASLPEG-----PGQQG-------HTPQLHTPSSSQ---EREQTPSEAMSQKAKETVSTRY 259
           +  PE      P ++         +P    P +S+     E++P     +++  +     
Sbjct: 564 SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA 623

Query: 260 TQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPL--------------TTPKPRKLPPNI 305
           ++  PPP   P +   E++P+S   +  SRL+PL               +P P + P + 
Sbjct: 624 SRLSPPPEDSPMSPPPEESPMSPPPEV-SRLSPLPVVSRLSPPPEESPLSPPPEESPTSP 682

Query: 306 VLKSSRSS--FHSDPQHWLSRHTEAA-PGDSGLISCSLQEQRKARKEALEKLGLPQDQD- 361
             ++SR S      P       + A+ P +  L+S  L+E           L LP++   
Sbjct: 683 PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES--------PLLPLPEEPQL 734

Query: 362 ---EPGLHLS----KPTSSIRPKE------TRAQHLSPAPGLAQP---AAPAQASAAIPA 405
                G HLS    +P  S RP+E          HLSP P   +P   A P +   +  A
Sbjct: 735 CPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP--EEPCLCAVPEEPHLSPQA 792

Query: 406 AGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLT 465
            G  L+  P       Q   P  SP P     S   P     +P++      P+PE    
Sbjct: 793 EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS-PQPEESHLSPQSEEPCLSPRPEESHL 851

Query: 466 LQESNTPGL 474
             E   P L
Sbjct: 852 SPELEKPPL 860



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 93/383 (24%), Positives = 136/383 (35%), Gaps = 80/383 (20%)

Query: 103 QQGRTPRTVTES-----SSSHPPEPQGL------GLRSGSYSLPRNIHIARSQNFRKSTT 151
           Q G+T R+V E      S   PPEP          L       P+  H+   Q       
Sbjct: 353 QGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPL 412

Query: 152 QASSHNPGEPG-RLAPE---PEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFR-D 206
           Q  +   G+ G +L P+   P  E++     P ++P SP            PPPEA R  
Sbjct: 413 QCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTS----PPPEASRLS 468

Query: 207 TQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPP 266
             PE+   + LPE          LH    S+  E++P                    PPP
Sbjct: 469 PPPEELPASPLPEA---------LHL---SRPLEESPLS------------------PPP 498

Query: 267 AGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHT 326
              P +   E +P S  E+  S L+P     P + PP+  L++            LS   
Sbjct: 499 EESPLSPPPESSPFSPLEE--SPLSP-----PEESPPSPALETP-----------LSPPP 540

Query: 327 EAA----PGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQ 382
           EA+    P +   +S   +E   +      +L  P ++         P  S       A 
Sbjct: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMS---PPPEESPMSPPPEAS 597

Query: 383 HLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSP--APGNVAASKS 440
            L P P    P +P    + +    +A   +P P   P   P P +SP   P  V+    
Sbjct: 598 RLFP-PFEESPLSPPPEESPLSPPPEASRLSPPPEDSP-MSPPPEESPMSPPPEVSRLSP 655

Query: 441 MP-ISIPKAPRANSALTPPKPES 462
           +P +S    P   S L+PP  ES
Sbjct: 656 LPVVSRLSPPPEESPLSPPPEES 678



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 101/407 (24%), Positives = 143/407 (35%), Gaps = 66/407 (16%)

Query: 72   DESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQGLGL---R 128
            +ES  +  P   R  P  + +P   P E             +S +S PPE   + L    
Sbjct: 676  EESPTSPPPEASRLSPPPEDSPTSPPPE-------------DSPASPPPEDSLMSLPLEE 722

Query: 129  SGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVS-QSSQPRQAP---- 183
            S    LP    +       +S     S  P EP  L+P PE+  +S Q+ +P  +P    
Sbjct: 723  SPLLPLPEEPQLCP-----RSEGPHLSPRPEEP-HLSPRPEEPHLSPQAEEPHLSPQPEE 776

Query: 184  ----ASPQEAALDLDVV---LIPPPEAFR-DTQPEQCREASLPEGPGQQGHTPQLHTPSS 235
                A P+E  L        L P PE      Q E+   + +PE P       + H    
Sbjct: 777  PCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQ 836

Query: 236  SQEREQTPSEAMSQKAKETVSTRYT-QPQPPPAGLPQNARAEDAPL--SSGEDPNSRL-- 290
            S+E   +P    S  + E      + +P+ PP    Q    E+ PL    GE   S L  
Sbjct: 837  SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLG 896

Query: 291  --------APLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQE 342
                     P  +P P +LP +   + S S     PQ  L       P  S +I+ +   
Sbjct: 897  EPALSEPGEPPLSPLPEELPLSPSGEPSLS-----PQ--LMPPDPLPPPLSPIITAAAPP 949

Query: 343  QRKARKEALEKLGLPQDQDEPGLHLSKP---TSSIRPKETRAQHLSPAPGLAQPAAPAQA 399
                  E     G   D D P   L+ P   T    P E       P P +  P  P+  
Sbjct: 950  ALSPLGELEYPFGAKGDSD-PESPLAAPILETPISPPPEANCTDPEPVPPMILP--PSPG 1006

Query: 400  SAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISIP 446
            S   PA+   +   P P   P   PL   S  P N   S+  P ++P
Sbjct: 1007 SPVGPAS--PILMEPLP---PQCSPLLQHSLVPQNSPPSQCSPPALP 1048



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 80/349 (22%), Positives = 106/349 (30%), Gaps = 53/349 (15%)

Query: 179  PRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQ---CREASLPEGPGQQGHTPQLHTPSS 235
            PR +   PQ   L L     PP +A   + P      R  S  +   Q   TP+   P  
Sbjct: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPP 2392

Query: 236  SQ----EREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAED--APLSSGEDPNSR 289
                       PS+  S+      S   +Q    P  L   A       P     DP SR
Sbjct: 2393 ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSR 2452

Query: 290  ----------LAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAP-GDSGLISC 338
                       APL  P PR  PP +  K+   +  S           A P G+      
Sbjct: 2453 PPSRPQSRDPFAPLHKP-PRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511

Query: 339  SLQEQRKARKEALE---------KLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPG 389
            S Q     R              +   PQ   EP L    P   + P      H  P P 
Sbjct: 2512 SGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPT 2571

Query: 390  LAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSM-PISIPKA 448
            L +P    Q++    A G            P+  PL    P+ G+   S  + P+  P  
Sbjct: 2572 LGKP----QSTNYTVATGNF---------HPSGSPL---GPSSGSTGESYGLSPLRPP-- 2613

Query: 449  PRANSALTPPKPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLST 497
                S L PP P+  L            +       E  G G+ S L+T
Sbjct: 2614 ----SVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLAT 2658



 Score = 37.4 bits (85), Expect = 0.040
 Identities = 81/356 (22%), Positives = 123/356 (34%), Gaps = 82/356 (23%)

Query: 160  EPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPE 219
            E   L+PE EK  +S   +P + P  P +     ++ L PP                   
Sbjct: 847  EESHLSPELEKPPLSP--RPEKPPEEPGQCPAPEELPLFPP------------------- 885

Query: 220  GPGQQGHTPQLHTPSSSQERE----QTPSE-AMSQKAKETVSTRYTQPQPPPAGLPQNAR 274
             PG+   +P L  P+ S+  E      P E  +S   + ++S +   P P P  L     
Sbjct: 886  -PGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIIT 944

Query: 275  AEDAPLSS--GE-----------DPNSRLA------PLTTP------KPRKLPPNIVLKS 309
            A   P  S  GE           DP S LA      P++ P       P  +PP I+  S
Sbjct: 945  AAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPS 1004

Query: 310  SRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSK 369
              S         +       P  S L+  SL  Q             P     P L LS 
Sbjct: 1005 PGSPVGPASPILME---PLPPQCSPLLQHSLVPQNSP----------PSQCSPPALPLSV 1051

Query: 370  PT------SSIRPKETRAQHLSPAPGLAQPAAPA---QASAAIPA-AGKALAQAPAPAP- 418
            P+        +   +    H      +++P  PA    A++ +P+  G     AP+PAP 
Sbjct: 1052 PSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPA 1111

Query: 419  -----GPAQGPLPMKS-PAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQE 468
                 G  +   P+    APG+       P S+    + +  L  P+  + +T  E
Sbjct: 1112 LDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPME 1167



 Score = 36.6 bits (83), Expect = 0.068
 Identities = 35/153 (22%), Positives = 59/153 (38%), Gaps = 7/153 (4%)

Query: 326 TEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLS 385
           T   P + G + C  +   KA  +   +L  P +++ P L   + +    P E       
Sbjct: 402 TSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP 461

Query: 386 PAPGLAQPAAPAQASAAIPAA---GKALAQAPAPAPGPAQGPL---PMKSPAPGNVAASK 439
           P      P      ++ +P A    + L ++P  +P P + PL   P  SP      +  
Sbjct: 462 PEASRLSPPPEELPASPLPEALHLSRPLEESPL-SPPPEESPLSPPPESSPFSPLEESPL 520

Query: 440 SMPISIPKAPRANSALTPPKPESGLTLQESNTP 472
           S P   P +P   + L+PP   S L+     +P
Sbjct: 521 SPPEESPPSPALETPLSPPPEASPLSPPFEESP 553



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 111/460 (24%), Positives = 149/460 (32%), Gaps = 82/460 (17%)

Query: 58   IGSLDTEADSGLSTDESEPATTPRG-----------FRALPITQPT--PRGGPEETITQQ 104
            IGS  T A  GLST        P G           F  LP   P   P   P       
Sbjct: 2126 IGSPTTPA--GLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAY 2183

Query: 105  GRTPRTVTESSSSHPPEPQGLGLRSGSYSLPRNIHIARSQNFRKSTTQASS--HNPGEPG 162
               PR  T +  ++PP P   G  +    L  +      Q     TT   +  H P  P 
Sbjct: 2184 PLEPRFPT-APPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPD 2242

Query: 163  RLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPP----EAFRDTQPEQCREASLP 218
                +P    +   + P        +A+   + +L PPP        + + E+   +S  
Sbjct: 2243 PFL-KPRCPSLDNLAVPESPGVGGGKAS---EPLLSPPPFGESRKALEVKKEELGASSPS 2298

Query: 219  EGPGQQGHTPQLHTPSSSQE----REQTPSEAMSQKAKETVSTRYTQPQPPPAGL----- 269
             GP   G    + +PSS         +TP      KA  T      +PQ P  GL     
Sbjct: 2299 YGPPNLGF---VDSPSSGTHLGGLELKTPDVF---KAPLTPRASQVEPQSPGLGLRPQEP 2352

Query: 270  -PQNARAEDAPL-------SSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHW 321
             P  A A   P         S  DP ++  P  TP+P+  PP         S  SDP   
Sbjct: 2353 PPAQALAPSPPSHPDIFRPGSYTDPYAQ--PPLTPRPQPPPPESCCALPPRSLPSDP--- 2407

Query: 322  LSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSKPTSSIRPKETRA 381
             SR   A+P         L  +  + +        P+ Q         P    RP  +R 
Sbjct: 2408 FSR-VPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ--------SPDPYSRP-PSRP 2457

Query: 382  QHLSPAPGLAQPAAPAQASAAIPA---------AGKALAQAPAPAPGPAQGPLPMKSP-- 430
            Q   P   L +P  P     A  A         AG   A  PA   G     +P   P  
Sbjct: 2458 QSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPN 2517

Query: 431  ---APGN---VAASKSMPISIPKAPRANSALTPPKPESGL 464
               +PG    V     M  + P+A     +L PP P+ GL
Sbjct: 2518 FVRSPGTGAFVGTPSPMRFTFPQAV-GEPSLKPPVPQPGL 2556



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 83/353 (23%), Positives = 124/353 (35%), Gaps = 89/353 (25%)

Query: 131 SYSLPRNIHIARSQNFRKSTTQ-----ASSHNPGEPGRL-APEPEKEQVSQSSQPRQAPA 184
           +YSL    H A+     +S  +      S  +P EPG     EP+   V+   QP+    
Sbjct: 342 NYSLCHRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHV 401

Query: 185 SPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPS 244
           +  +                ++  P QC   + P G       PQL  P +    E+ P 
Sbjct: 402 TSMQP---------------KEPGPLQCE--AKPLGKAGVQLEPQLEAPLN----EEMPL 440

Query: 245 EAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPN 304
                              PPP   P +   E++P S   +  SRL+P     P +LP +
Sbjct: 441 ------------------LPPPEESPLSPPPEESPTSPPPEA-SRLSP----PPEELPAS 477

Query: 305 IVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDEPG 364
            + ++            LSR  E +P        S   +        E       ++ P 
Sbjct: 478 PLPEALH----------LSRPLEESP-------LSPPPEESPLSPPPESSPFSPLEESP- 519

Query: 365 LHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAP-----APG 419
             LS P  S  P       LSP P  A P +P    + +    + L  +P P     +P 
Sbjct: 520 --LSPPEES-PPSPALETPLSPPPE-ASPLSPPFEESPLSPPPEELPTSPPPEASRLSPP 575

Query: 420 PAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTP 472
           P + P+   SP P      +  P+S P  P A S L PP  ES L+     +P
Sbjct: 576 PEESPM---SPPP------EESPMSPP--PEA-SRLFPPFEESPLSPPPEESP 616



 Score = 30.4 bits (67), Expect = 4.9
 Identities = 119/527 (22%), Positives = 188/527 (35%), Gaps = 80/527 (15%)

Query: 82   GFRALPITQPTPRGGPEETITQQGRTPRTV--------TESSSSHPPEPQGLGLRSGSYS 133
            G  A P+   +  G    T+   G+   TV        TE  S+H   P  +G    S +
Sbjct: 4000 GMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA 4059

Query: 134  L-PRNIHIARSQNFR------KSTTQASSHNPGEPGRLAPEPEKEQVSQ------SSQPR 180
              P  +  + S + +      +   Q SS     P RL P  +++QVS        S  +
Sbjct: 4060 TEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRL-PGQQQQQVSLLHTAGGGSHGQ 4118

Query: 181  QAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQERE 240
                S  EA+  +  +L  P  +  D QP    +  L  GP Q    P L  P  +    
Sbjct: 4119 LGSGSSSEAS-SVPHLLAQPSVSLGD-QPGSMTQNLL--GPQQ----PMLERPMQNNTGP 4170

Query: 241  QTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRK 300
            Q P      ++ + +         P  G+        A L      N +L  L+  + ++
Sbjct: 4171 QPPKPGPVLQSGQGL---------PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQ 4221

Query: 301  LPPNIV---LKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEA--LEKLG 355
            L   ++   L+ S++   + P  +    T+ +P   GL+ C  Q       +   L++LG
Sbjct: 4222 LQALLMQRQLQQSQAVRQTPP--YQEPGTQTSPLQ-GLLGCQPQLGGFPGPQTGPLQELG 4278

Query: 356  L-PQDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKAL---A 411
              P+ Q  P L       S  P         P     +P  P+Q    +P+    L   A
Sbjct: 4279 AGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQ----LPSPSSQLPTEA 4334

Query: 412  QAPAPAPGPAQGPLPMKSPAPGNVAASKSMPISI-------PKAPRANSALTPPKPESGL 464
            Q P   PG  +   P   P PG V+ + +            P  P  N A T    +S L
Sbjct: 4335 QLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSL 4394

Query: 465  T---LQESN---TPGLRQMNFKSNTLER-SGVGLSSY---LSTEKDASPKTSTSLGKGSF 514
                L + N    P   Q++ K    E    +G  S     + E   +P TS  L     
Sbjct: 4395 VPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGP 4454

Query: 515  LDKISPSVLRN-SRPRPASLGTGKDFAGIQV-------GKLADLEQE 553
              +    +L+   R +   L TG+   G++         KLA LEQ+
Sbjct: 4455 RSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQK 4501


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 69/295 (23%), Positives = 106/295 (35%), Gaps = 26/295 (8%)

Query: 172 QVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLH 231
           +V  SS P       ++  L +++V+    +A     P Q R+     G G  G TP   
Sbjct: 386 EVVGSSMPLIGDHQDEDKQLIVELVVNKMAQAL----PRQ-RQRDASPGRGSHGQTP--- 437

Query: 232 TPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLA 291
           +P +     QT  +     A++    +   PQP P    Q    +  P   G+   S L 
Sbjct: 438 SPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLG 497

Query: 292 PLT-TPKPRKLPPNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEA 350
           P   +P P++LP         +S  + P     R +    G  G    +   +  A    
Sbjct: 498 PPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAA---RPPASPSP 554

Query: 351 LEKLGLPQDQDEPGLHLSKPTSSIRPKETRAQHLSPA---PGLAQPAAPAQASAAIPAAG 407
             + G PQ   +  +    P  +        Q   P    PG A P   A  +  +P  G
Sbjct: 555 QRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTG 614

Query: 408 KALAQAPAPA-PGPAQGPLPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPE 461
               Q P P+ PGPA  P P  +  P     S+ +P      P   +A  PP P+
Sbjct: 615 PPTTQQPRPSGPGPAGRPKPQLAQKP-----SQDVP-----PPATAAAGGPPHPQ 659



 Score = 36.2 bits (82), Expect = 0.089
 Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 14/149 (9%)

Query: 159 GEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQPEQCREASLP 218
           G P +  P P+ +Q      P      PQ           P  +A   TQ +  +   + 
Sbjct: 478 GPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537

Query: 219 EGPGQQGHTPQLHTPSS-SQEREQTPSEAMSQKAKETVSTRYTQPQPPPA-GLPQNARAE 276
            GPG     P    P+S S +R+  P +A  Q       T  + P PP A G P   +  
Sbjct: 538 GGPGA---PPAARPPASPSPQRQAGPPQATRQ-------TSVSGPAPPKASGAPPGGQQR 587

Query: 277 DAPLSSGEDP--NSRLAPLTTPKPRKLPP 303
             P      P   +R A    P PR  PP
Sbjct: 588 QGPPQKPPGPAGPTRQASQAGPVPRTGPP 616



 Score = 29.6 bits (65), Expect = 8.3
 Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 3/46 (6%)

Query: 412 QAPAPAPGPAQGPLPMKSPAPGNVAASKS---MPISIPKAPRANSA 454
           Q P P P P     P  +P PG   A +S    P + P AP   S+
Sbjct: 26  QRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSS 71


>gi|223633935 hypothetical protein LOC254427 [Homo sapiens]
          Length = 435

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 60/248 (24%), Positives = 93/248 (37%), Gaps = 39/248 (15%)

Query: 17  TRVGSCDSMMSSTSTRSGS-SDSSYDFLSTEEKECLLFLEETIGSLDTEADSGLSTD--- 72
           +R GS +S  SS+ +RS +  D S  +L+ EEK+ LLF EETI SLD + +  +  D   
Sbjct: 27  SRGGSLESRSSSSRSRSFTLDDESLKYLTHEEKDVLLFFEETIDSLDEDFEEPVLCDGGV 86

Query: 73  --------ESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQG 124
                   E   ++       + + QP P  G  E +           E + +  P P G
Sbjct: 87  CCLCSPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGL----------PEGTQAAGPAPAG 136

Query: 125 LGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPA 184
                            +    + + T      P     LAP P         +  +AP+
Sbjct: 137 -----------------KEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPS 179

Query: 185 SPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPS 244
            P E    L  V  P   A + ++     EA  P  P ++G   +  TP++   R   P 
Sbjct: 180 PPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPG 239

Query: 245 EAMSQKAK 252
              S  A+
Sbjct: 240 PGPSHPAQ 247



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 69/286 (24%), Positives = 103/286 (36%), Gaps = 42/286 (14%)

Query: 357 PQDQDEPGLHLSKPTSSIRPKETRAQHLSPAP---------GLAQPAAPAQASAAIPAAG 407
           P D   P   L+ P     P   R +  +P+P          +  P   AQ  +   A  
Sbjct: 149 PPDPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGN 208

Query: 408 KALAQ-APAPAPGPAQGPLPM-KSPAPGNVAASKSMPISIPKAPR-------ANSALTPP 458
           +AL+  +P     P +   P  + P  G+     S P   PKAPR        N A   P
Sbjct: 209 EALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQ-PKAPRFPSNIIVTNGAAREP 267

Query: 459 K---PESGLTLQESNTPGLRQMNFKSNTLERSGV--------GLSSYLSTEKDASPKTST 507
           +     + +++QE     L  ++  +     +G         G S          P  + 
Sbjct: 268 RRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAE 327

Query: 508 SLG------KGSFLDKISPSVLRNSRPRPASLG-TGKDFAGIQVGKLADLEQEQS----- 555
           SL       +G  L    PS     +  P+S    GK         L      QS     
Sbjct: 328 SLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGPR 387

Query: 556 SKRLSYQGQSRDKLPRPPCVSVKISPKGVPNEHRREALKKLGLLKE 601
               +   +  D LPRP  ++V+ + +G   E RREAL+KLGLL+E
Sbjct: 388 QPNGAQDWRRADSLPRPQGITVQFAGRGSSEEARREALRKLGLLRE 433



 Score = 33.5 bits (75), Expect = 0.58
 Identities = 34/108 (31%), Positives = 41/108 (37%), Gaps = 9/108 (8%)

Query: 367 LSKPTSSIRPKETRAQHLSPAPGLAQPAA-PAQASAAIPA-AGKALAQAPAPAPGPAQGP 424
           L + TSS    E     + PAPG  +    P    AA PA AGK   +  A  P P    
Sbjct: 94  LEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPD-- 151

Query: 425 LPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTP 472
                PAP  + A   +P S P  PR       P  E    L+   TP
Sbjct: 152 ----PPAPETLLAPPPLP-STPDPPRRELRAPSPPVEHPRLLRSVPTP 194


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 52/150 (34%), Positives = 70/150 (46%), Gaps = 12/150 (8%)

Query: 385 SPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQGPLPMKSPAPGNVAASKSMPIS 444
           +PAP LA  AAPA A+AA PA   A A APAPA  PA    P    A  + A S S   S
Sbjct: 517 APAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAP---AAAASAAPSHSQKPS 573

Query: 445 IP--KAPRANSALTPP----KPESGLTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTE 498
           +P  +A R   A  PP    K    + L+  +T GL+ +N +        +G SS+   +
Sbjct: 574 VPLIQASRPCPAAQPPTKFIKIAPAIQLRTGST-GLKAINVEGPVQGAQALG-SSFKPVQ 631

Query: 499 KDASPKTSTSLGKGSFLDKISPSVLRNSRP 528
              S   + +   GS L   S   L ++RP
Sbjct: 632 APGSGAPAPAGISGSDLQS-SGGPLPDARP 660



 Score = 36.2 bits (82), Expect = 0.089
 Identities = 99/502 (19%), Positives = 172/502 (34%), Gaps = 100/502 (19%)

Query: 148 KSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDT 207
           K +   S ++P   G++ P  +  Q SQ S  +  P        D    L P  E     
Sbjct: 351 KPSIMQSFNDPLLCGKIRPRKKARQKSQKSPWQPFPD-------DHSACLRPGSETDAGR 403

Query: 208 QPEQCREA--SLPEGPGQQGHTPQLHTPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPP 265
              Q +E+  S  +GPG+  H+       S     +TP +      + +VS +  +  PP
Sbjct: 404 AVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPP 463

Query: 266 PAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKLPPNIVLKSSRSSFHSDPQHWLSRH 325
              LP ++      +SSG        P     P K P +     + ++  +      +  
Sbjct: 464 RTQLPSSS----GKISSGNS----FPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAA 515

Query: 326 TEAAPGDSG-----LISCSLQEQRKARKEALEKLGLPQDQDEPGLHLSK-PTSSIRPKET 379
              AP  +      L + +      A   A      P     P    S  P+ S +P   
Sbjct: 516 AAPAPALAAAAAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVP 575

Query: 380 RAQHLSPAPGLAQPA------------------------APAQASAAIPAAGKALAQAPA 415
             Q   P P    P                          P Q + A+ ++ K +    +
Sbjct: 576 LIQASRPCPAAQPPTKFIKIAPAIQLRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGS 635

Query: 416 PAPGPAQ----------GPLP--------MKSPAPGNVAASKS---MPISIPKAPRANSA 454
            AP PA           GPLP          SPAP     +      P+++ + P+ ++ 
Sbjct: 636 GAPAPAGISGSDLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAV 695

Query: 455 LTPPKPESG--LTLQESNTPGLRQMNFKSNTLERSGVGLSSYLSTEKDASPKTSTSLGKG 512
           LT P+ +S   ++LQ+   P        ++  +    G +  LST+  A P         
Sbjct: 696 LTGPQQQSHQLVSLQQLQQP------TAAHPPQPGPQGSALGLSTQGQAFPAQQ------ 743

Query: 513 SFLDKISPSVLRNS---RPRPASLGTGKDFAGIQVGKLADLEQEQSSKRLSYQGQSRDKL 569
             L K++P+  R+    +P+PA L             L   +  Q   +L    + +   
Sbjct: 744 --LLKVNPTRARSGLQPQPQPAVLSL-----------LGSAQVPQQGVQLPSVLRQQQPQ 790

Query: 570 PRPPCVSVKISPKGVPNEHRRE 591
           P+PP   +++ P+  P   + +
Sbjct: 791 PQPP--KLQLQPQWQPKPRQEQ 810


>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
            sapiens]
          Length = 1188

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 66/255 (25%), Positives = 94/255 (36%), Gaps = 43/255 (16%)

Query: 91   PTPRGGPEETITQQGRTPRTVTESSSSHPPE--PQGLGLRSGSYSLPRNIHIARSQNFRK 148
            PTP G P   I+ +   P T          E  P  LG  +G      ++ + + + F  
Sbjct: 961  PTPPGQPP--ISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFEN 1018

Query: 149  STTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPASPQEAALDLDVVLIPPPEAFRDTQ 208
                + S  P       P P K+Q S     ++ P  P+   L   +VL           
Sbjct: 1019 PLYGSLSSFP------KPAPRKDQESPKMPRKEPPPCPEPGILSPSIVL----------- 1061

Query: 209  PEQCREASLPEGPGQQGHTPQLH--TPSSSQEREQTPSEAMSQKAKETVSTRYTQPQPPP 266
              + +EA   EGPG+Q   P+L   T SSS E      +    K K  VS++     P P
Sbjct: 1062 -TKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQ----APVP 1116

Query: 267  AGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPR---KLPPNIVLKSSRSSFHSD----PQ 319
            A  P           S  + N +  P  TP+P    K P  + L+ S+   + D    P 
Sbjct: 1117 AKRPIK--------PSRSEINQQTPPTPTPRPPLPVKSPAVLHLQHSKGRDYRDNTELPH 1168

Query: 320  HWLSRHTEAAPGDSG 334
            H   R  E  PG  G
Sbjct: 1169 HGKHRPEEGPPGPLG 1183



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 76/317 (23%), Positives = 120/317 (37%), Gaps = 63/317 (19%)

Query: 148  KSTTQASSHNPGEPGRL---APEPEKEQVSQSSQPRQAPASPQEAALDLDV--VLIPP-- 200
            K+    +SH+P +   +   AP      +++   P      P    + L V   L P   
Sbjct: 878  KTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQ 937

Query: 201  PEAFRDTQPEQ------CREASLPEGPGQQGHTPQLHTPSSS------QEREQTPSEAMS 248
            P A+   QP +      CR  S P  PGQ   +P+   PS++      + +E  PS+ + 
Sbjct: 938  PTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSD-LG 996

Query: 249  QKAKETVSTR---YTQPQ--PPPAGLPQNARAEDAPLSSGEDPN-SRLAPLTTPKPRKLP 302
            + A +T+       T+P+    P     ++  + AP    E P   R  P   P+P  L 
Sbjct: 997  KNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILS 1056

Query: 303  PNIVLKSSRSSFHSDPQHWLSRHTEAAPGDSGLISCSLQEQRKARKEALEKLGLPQDQDE 362
            P+IVL  ++    +D      +   A    S   +CS   + +A        G  + Q +
Sbjct: 1057 PSIVLTKAQ---EADRGEGPGKQVPAPRLRS--FTCSSSAEGRA-------AGGDKSQGK 1104

Query: 363  PGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAAPAQASAAIPAAGKALAQAPAPAPGPAQ 422
            P      P SS                     AP  A   I  +   + Q   P P P +
Sbjct: 1105 P----KTPVSS--------------------QAPVPAKRPIKPSRSEINQQTPPTPTP-R 1139

Query: 423  GPLPMKSPAPGNVAASK 439
             PLP+KSPA  ++  SK
Sbjct: 1140 PPLPVKSPAVLHLQHSK 1156



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 55/239 (23%), Positives = 86/239 (35%), Gaps = 23/239 (9%)

Query: 247  MSQKAKETVS-----TRYTQPQPPPAGLPQNARAEDAPLSSGEDPNSRLAPLTTPKPRKL 301
            M    K+T+S     T ++  QPP        R E  P   G+ P S    L +   R L
Sbjct: 924  MPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGL 983

Query: 302  PPNIVLKSSRSSFHSDPQHWLSRH----TEAAPGDSGLISCSLQEQRKARKEALEKLGLP 357
            PP    +S  S    +    L +     T+    ++ L        + A ++  E   +P
Sbjct: 984  PPR-TQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMP 1042

Query: 358  QDQDEPGLHLSKPTSSIRPKETRAQHLSPAPGLAQPAA-----PAQASAAIPAAGKALAQ 412
            + +  P       + SI   + +       PG   PA         +SA   AAG   +Q
Sbjct: 1043 RKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPAPRLRSFTCSSSAEGRAAGGDKSQ 1102

Query: 413  APAPAPGPAQGPLPMKSPAPGNVAA--SKSMPISIPKAPRANSALTPPKPESGLTLQES 469
                 P  +Q P+P K P   + +    ++ P   P+ P       P K  + L LQ S
Sbjct: 1103 GKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPP------LPVKSPAVLHLQHS 1155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.124    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,795,480
Number of Sequences: 37866
Number of extensions: 1946755
Number of successful extensions: 17061
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 287
Number of HSP's successfully gapped in prelim test: 1382
Number of HSP's that attempted gapping in prelim test: 9475
Number of HSP's gapped (non-prelim): 5606
length of query: 601
length of database: 18,247,518
effective HSP length: 108
effective length of query: 493
effective length of database: 14,157,990
effective search space: 6979889070
effective search space used: 6979889070
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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