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Search of human proteins with 14424433
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14424433 ATPase, class V, type 10A [Homo sapiens]
(1499 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14424433 ATPase, class V, type 10A [Homo sapiens] 3002 0.0
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 1333 0.0
gi|149944474 ATPase, class V, type 10B [Homo sapiens] 1267 0.0
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 429 e-119
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 424 e-118
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 402 e-111
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 402 e-111
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 393 e-109
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 381 e-105
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 355 1e-97
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 345 2e-94
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 345 2e-94
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 344 4e-94
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 343 9e-94
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 330 5e-90
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 241 5e-63
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 235 3e-61
gi|41327760 ATPase, class II, type 9B [Homo sapiens] 233 8e-61
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 78 6e-14
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 78 6e-14
gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens] 74 8e-13
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens] 74 8e-13
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 74 1e-12
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 74 1e-12
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 70 2e-11
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 70 2e-11
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 69 3e-11
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 69 3e-11
gi|66932949 ATPase type 13A4 [Homo sapiens] 68 6e-11
gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens] 67 2e-10
>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
Length = 1499
Score = 3002 bits (7782), Expect = 0.0
Identities = 1499/1499 (100%), Positives = 1499/1499 (100%)
Query: 1 MEREPAGTEEPGPPGRRRRREGRTRTVRSNLLPPPGAEDPAAGAAKGERRRRRGCAQHLA 60
MEREPAGTEEPGPPGRRRRREGRTRTVRSNLLPPPGAEDPAAGAAKGERRRRRGCAQHLA
Sbjct: 1 MEREPAGTEEPGPPGRRRRREGRTRTVRSNLLPPPGAEDPAAGAAKGERRRRRGCAQHLA 60
Query: 61 DNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILA 120
DNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILA
Sbjct: 61 DNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILA 120
Query: 121 ITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPAD 180
ITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPAD
Sbjct: 121 ITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPAD 180
Query: 181 ILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDL 240
ILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDL
Sbjct: 181 ILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDL 240
Query: 241 SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS 300
SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS
Sbjct: 241 SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS 300
Query: 301 KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY 360
KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY
Sbjct: 301 KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY 360
Query: 361 SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ 420
SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ
Sbjct: 361 SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ 420
Query: 421 IQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPRGGSVSQ 480
IQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPRGGSVSQ
Sbjct: 421 IQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPRGGSVSQ 480
Query: 481 RGSIGSHQSVRVVHRTQSTKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEK 540
RGSIGSHQSVRVVHRTQSTKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEK
Sbjct: 481 RGSIGSHQSVRVVHRTQSTKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEK 540
Query: 541 VSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRTKVRVRFELK 600
VSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRTKVRVRFELK
Sbjct: 541 VSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRTKVRVRFELK 600
Query: 601 SPVKTIEDFLRRFTPSCLTSGCSSIGSLAANKSSHKLGSSFPSTPSSDGMLLRLEERLGQ 660
SPVKTIEDFLRRFTPSCLTSGCSSIGSLAANKSSHKLGSSFPSTPSSDGMLLRLEERLGQ
Sbjct: 601 SPVKTIEDFLRRFTPSCLTSGCSSIGSLAANKSSHKLGSSFPSTPSSDGMLLRLEERLGQ 660
Query: 661 PTSAIASNGYSSQADNWASELAQEQESERELRYEAESPDEAALVYAARAYNCVLVERLHD 720
PTSAIASNGYSSQADNWASELAQEQESERELRYEAESPDEAALVYAARAYNCVLVERLHD
Sbjct: 661 PTSAIASNGYSSQADNWASELAQEQESERELRYEAESPDEAALVYAARAYNCVLVERLHD 720
Query: 721 QVSVELPHLGRLTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCS 780
QVSVELPHLGRLTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCS
Sbjct: 721 QVSVELPHLGRLTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCS 780
Query: 781 SVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENS 840
SVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENS
Sbjct: 781 SVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENS 840
Query: 841 EELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIA 900
EELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIA
Sbjct: 841 EELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIA 900
Query: 901 YACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPP 960
YACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPP
Sbjct: 901 YACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPP 960
Query: 961 STSTASGRRPSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRS 1020
STSTASGRRPSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRS
Sbjct: 961 STSTASGRRPSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRS 1020
Query: 1021 KLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHW 1080
KLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHW
Sbjct: 1021 KLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHW 1080
Query: 1081 CYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGV 1140
CYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGV
Sbjct: 1081 CYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGV 1140
Query: 1141 LDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDL 1200
LDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDL
Sbjct: 1141 LDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDL 1200
Query: 1201 FTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSN 1260
FTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSN
Sbjct: 1201 FTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSN 1260
Query: 1261 PYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRKSPRRCSA 1320
PYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRKSPRRCSA
Sbjct: 1261 PYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRKSPRRCSA 1320
Query: 1321 PKETFAQGRLPKDSGTEHSSGRTVKTSVPLSQPSWHTQQPVCSLEASGEPSTVDMSMPVR 1380
PKETFAQGRLPKDSGTEHSSGRTVKTSVPLSQPSWHTQQPVCSLEASGEPSTVDMSMPVR
Sbjct: 1321 PKETFAQGRLPKDSGTEHSSGRTVKTSVPLSQPSWHTQQPVCSLEASGEPSTVDMSMPVR 1380
Query: 1381 EHTLLEGLSAPAPMSSAPGEAVLRSPGGCPEESKVRAASTGRVTPLSSLFSLPTFSLLNW 1440
EHTLLEGLSAPAPMSSAPGEAVLRSPGGCPEESKVRAASTGRVTPLSSLFSLPTFSLLNW
Sbjct: 1381 EHTLLEGLSAPAPMSSAPGEAVLRSPGGCPEESKVRAASTGRVTPLSSLFSLPTFSLLNW 1440
Query: 1441 ISSWSLVSRLGSVLQFSRTEQLADGQAGRGLPVQPHSGRSGLQGPDHRLLIGASSRRSQ 1499
ISSWSLVSRLGSVLQFSRTEQLADGQAGRGLPVQPHSGRSGLQGPDHRLLIGASSRRSQ
Sbjct: 1441 ISSWSLVSRLGSVLQFSRTEQLADGQAGRGLPVQPHSGRSGLQGPDHRLLIGASSRRSQ 1499
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 1333 bits (3449), Expect = 0.0
Identities = 706/1315 (53%), Positives = 922/1315 (70%), Gaps = 36/1315 (2%)
Query: 61 DNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILA 120
+NR++TTKYTLL+F+P+NLFEQFHR AN+YF+F+ +LN+VP V AFQ + + P++ +L
Sbjct: 73 NNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLT 132
Query: 121 ITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPAD 180
I A +D EDY +++ D +IN+L V+SR+EKKY++R WK++ VGDF+RL CNE+ PAD
Sbjct: 133 IIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVIPAD 192
Query: 181 ILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDL 240
++LL S+DPDG+CHIET+ LDGE+NLK+RQVVRG++E SE +P F+S IECE PNNDL
Sbjct: 193 MVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRIECESPNNDL 252
Query: 241 SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS 300
SRFRG + H N ++ GL KENLLLRGCT+RNT+AVVGIV+YAGHETKA+LNNSGPRYKRS
Sbjct: 253 SRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRS 312
Query: 301 KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY 360
KLER+ N DVLWCV+LLV M L AVGHG+W+ RY EK F VP+ DG +SP+ A Y
Sbjct: 313 KLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRY-EKMHFFNVPEPDGHIISPLLAGFY 371
Query: 361 SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ 420
F TMII+LQVLIPISLYVSIEIVK Q+YFI D+ Y+E+ DS +QCRALNI EDLGQ
Sbjct: 372 MFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAEDLGQ 431
Query: 421 IQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPR-GGSVS 479
IQY+FSDKTGTLTENKMVFRRC+V+G +Y H+ NA+RL YQEA SE+E+ + GS+S
Sbjct: 432 IQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENARRLESYQEAVSEDEDFIDTVSGSLS 491
Query: 480 QRGSIGSHQSVRVVHRTQ--STKSHRRTGSR-----AEAKRASMLSKHTAFSSPMEKDIT 532
+ S R VH + S+ GS E S+ AFSSP+E D+
Sbjct: 492 NMAKPRA-PSCRTVHNGPLGNKPSNHLAGSSFTLGSGEGASEVPHSRQAAFSSPIETDVV 550
Query: 533 PDPKLLEKVSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRTK 592
PD +LL+K S+ L + + + + E + DFFIAL ICNTVVV++P+QPR K
Sbjct: 551 PDTRLLDKFSQITPRLFMPL--DETIQNPPMETLYIIDFFIALAICNTVVVSAPNQPRQK 608
Query: 593 VRVRFELKSPVKTIEDF--------LRRFTPSCLTSGCS-SIGSLAANKSSHKLGSSF-P 642
+R P+K++E+ +RR + L SG S G A S L S P
Sbjct: 609 IRHPSLGGLPIKSLEEIKSLFQRWSVRRSSSPSLNSGKEPSSGVPNAFVSRLPLFSRMKP 668
Query: 643 STPSSDGMLLRLEERLGQPTSAIASNGYSSQAD----NWASELAQEQESERELRYEAESP 698
++P + + E +SA + D N +E Q L YEAESP
Sbjct: 669 ASPVEEEVSQVCESPQCSSSSACCTETEKQHGDAGLLNGKAESLPGQPLACNLCYEAESP 728
Query: 699 DEAALVYAARAYNCVLVERLHDQVSVELPHLGRLTFELLHTLGFDSVRKRMSVVIRHPLT 758
DEAALVYAARAY C L R +QV V+ LG LTF+LLH L FDSVRKRMSVV+RHPL+
Sbjct: 729 DEAALVYAARAYQCTLRSRTPEQVMVDFAALGPLTFQLLHILPFDSVRKRMSVVVRHPLS 788
Query: 759 DEINVYTKGADSVVMDLLQPCSSVDARGRHQKKI-RSKTQNYLNVYAAEGLRTLCIAKRV 817
+++ VYTKGADSV+M+LL S A Q+ I R KTQ +L+ YA +GLRTLCIAK+V
Sbjct: 789 NQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKV 848
Query: 818 LSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISK 877
+S EYA WL++H AE+S++N EELL +SA+RLE L LLGATGIEDRLQ+GVPE+I
Sbjct: 849 MSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEA 908
Query: 878 LRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSR 937
L +AG++IW+LTGDKQETAVNIAYACKLL+ D+++ LN S++AC L+ L +Q +
Sbjct: 909 LHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMSTILKELQKK 968
Query: 938 GLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKNLEDKFLFLAKQ 997
Q PE+ VS+ L PP SG R L+I G++L +AL+++L+ +FL L
Sbjct: 969 -TQALPEQ----VSLSEDLLQPP-VPRDSGLRAGLIITGKTLEFALQESLQKQFLELTSW 1022
Query: 998 CRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAV 1057
C++V+CCR+TPLQKS VVKLVRS L+ MTLAIGDGANDVSMIQVAD+G+G+SGQEGMQAV
Sbjct: 1023 CQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAV 1082
Query: 1058 MASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTM 1117
MASDFAV +F++L +LL++HGHWCY+RL+NM+LYFFYKN +V LLFW+QFFCGFS ++M
Sbjct: 1083 MASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSM 1142
Query: 1118 IDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMAD 1177
D W LIFFNLLF+S PP++ GVL++DV A L+ P+LY+SGQ E Y P TFW + D
Sbjct: 1143 TDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLD 1202
Query: 1178 AAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFS 1237
A +QSLVCF +PY Y S+ D+F +G P+ T AL LLHL IE+K+ TW++ + S
Sbjct: 1203 AFYQSLVCFFVPYFTYQGSDTDIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGS 1262
Query: 1238 VLLFFTVALIYNASCATCYPPSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQG 1297
+L +F A+++ A C TC PPSNPYW MQ + DPVFYL C++T ALLPR +R LQG
Sbjct: 1263 ILSYFLFAIVFGAMCVTCNPPSNPYWIMQEHMLDPVFYLVCILTTSIALLPRFVYRVLQG 1322
Query: 1298 RVFPTQLQLARQLTRKSP-RRCSAPKETFAQGRLPKDSG--TEHSSGRTVKTSVP 1349
+FP+ + A+ R +P R A K+ G++ + + S+G++ + +P
Sbjct: 1323 SLFPSPILRAKHFDRLTPEERTKALKKWRGAGKMNQVTSKYANQSAGKSGRRPMP 1377
>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
Length = 1461
Score = 1267 bits (3279), Expect = 0.0
Identities = 686/1352 (50%), Positives = 900/1352 (66%), Gaps = 59/1352 (4%)
Query: 62 NRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAI 121
NR TTKYTL +FLP+NLFEQFHR AN+YF+F+ +LN++P++ F + + P+ +L +
Sbjct: 69 NRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLFV 128
Query: 122 TAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADI 181
+D ED+ RHR D IN ++ R+E+ YV + WK++ VGDF++++CNEI PADI
Sbjct: 129 IMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIVPADI 188
Query: 182 LLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLS 241
LLL SSDP+G+CH+ETA+LDGETNLK+R VV+GFS+ +F P F + I CEKPNN L+
Sbjct: 189 LLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIVCEKPNNHLN 248
Query: 242 RFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSK 301
+F+G + H + + G E+LLLRGCT+RNT+ VGIVIYAGHETKA+LNNSGPRYKRSK
Sbjct: 249 KFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSK 308
Query: 302 LERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYS 361
+ER+MN D+ +C+ +L+ M L AVGH +W ++E F VP ++GS L Y
Sbjct: 309 IERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPP-FDVPDANGSFLPSALGGFYM 367
Query: 362 FLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQI 421
FLTMII+LQVLIPISLYVSIE+VK QV+F++ D+ LYDEETD +QCRALNI EDLGQI
Sbjct: 368 FLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQI 427
Query: 422 QYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVP-RGGSVSQ 480
QYIFSDKTGTLTENKMVFRRCT+ G EYSH NA+RL +E DS+ EE + S S
Sbjct: 428 QYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQYQCLSFSA 487
Query: 481 R-----GSIGSHQSVRVVHRTQSTK----SHRRTGSRAEAKRASMLSKHTAFSSPMEKDI 531
R ++ S + + + R+QS + H R S + + AFSS +EKD+
Sbjct: 488 RWAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQ---PPVAFSSSIEKDV 544
Query: 532 TPDPKLLEKVSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRT 591
TPD LL KV + L A LS S + DFF+ALTICN+V+V++ +PR
Sbjct: 545 TPDKNLLTKVRDAALWLETLSDSRPAKASLSTT-SSIADFFLALTICNSVMVSTTTEPRQ 603
Query: 592 KVRVRFELKSPVKTIEDFLRRFTPSCLTSGCSSIGSLAANKSS--HKLGSSFPSTPSSDG 649
+V ++ K+ ++E + F L S S S A + + LG++ +T S +
Sbjct: 604 RVTIKPSSKALGTSLEKIQQLFQKLKLLSLSQSFSSTAPSDTDLGESLGANVATTDSDE- 662
Query: 650 MLLRLEERLGQPTSAIASNGYSS----QAD----------NWASELAQEQESERELRYEA 695
R + + + GY S Q D A E + E YEA
Sbjct: 663 ---RDDASVCSGGDSTDDGGYRSSMWDQGDILESGSGTSLEEALEAPATDLARPEFCYEA 719
Query: 696 ESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLTFELLHTLGFDSVRKRMSVVIRH 755
ESPDEAALV+AA AY+ LV R +QV+V LP LTF LL TLGFDSVRKRMSVV+RH
Sbjct: 720 ESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVVVRH 779
Query: 756 PLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQK--KIRSKTQNYLNVYAAEGLRTLCI 813
PLT EI VYTKGADSV+MDLL+ + V +K KIR++TQ +L++YA +GLRTLCI
Sbjct: 780 PLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCI 839
Query: 814 AKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPE 873
AK+V+S+E++ W EAE+SL+N +ELL ++A LE L LLGATGIEDRLQ+GVP+
Sbjct: 840 AKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPD 899
Query: 874 TISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCY 933
TI+ LR+AG+Q+WVLTGDKQETAVNIA++C+LL+ + V T+N +QE C ++L+ L
Sbjct: 900 TIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEE 959
Query: 934 V-QSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKNLEDKFL 992
+ Q R LQ+ K G R S P TS A LVIDG++L + LE KFL
Sbjct: 960 LKQFRELQKPDRKLFG---FRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFL 1016
Query: 993 FLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQE 1052
L + CRSVLCCRSTPLQKSM+VKLVR KL+ MTL+IGDGANDVSMIQ AD+G+GISGQE
Sbjct: 1017 ELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQE 1076
Query: 1053 GMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGF 1112
GMQAVM+SDFA+ +F++L++LL++HGHWCYSRLA MV+Y+ YKN +V LLFW+QFFCGF
Sbjct: 1077 GMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGF 1136
Query: 1113 SASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFW 1172
S+STMID W +IFFNL F+SLPPLV GVLD+D+ A LL P+LYKSGQN E Y TFW
Sbjct: 1137 SSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFW 1196
Query: 1173 FNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWI 1232
+M DA +QSL+CF IPYLAY S++D+FT+GTPI TI+L T LLH +E KTWT + +
Sbjct: 1197 ISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGV 1256
Query: 1233 TCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFF 1292
S L++F V+L+YNA+C C P+NPYW M+ L +P FYL C +TPV ALLPR FF
Sbjct: 1257 VLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFF 1316
Query: 1293 RSLQGRVFPTQLQLARQLTRKSPRRCSAPKETFAQGRLPKDSGTEHSSGRTVKTSVPLSQ 1352
SLQG + + A+++ + P + E S R+ + P+ +
Sbjct: 1317 LSLQGTCGKSLISKAQKIDKLPPDK----------------RNLEIQSWRSRQRPAPVPE 1360
Query: 1353 PSWHTQQPVCSLEASGEPSTVDMSM--PVREH 1382
+ T PV S+ ++ S P R+H
Sbjct: 1361 VARPTHHPVSSITGQDFSASTPKSSNPPKRKH 1392
>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
Length = 1223
Score = 429 bits (1102), Expect = e-119
Identities = 254/650 (39%), Positives = 384/650 (59%), Gaps = 36/650 (5%)
Query: 684 EQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGF 742
E+++E EL Y+A+SPDE ALV AAR + V R ++V +G +T++LL L F
Sbjct: 513 EEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVH--EMGTAITYQLLAILDF 570
Query: 743 DSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNV 802
+++RKRMSV++R+P +I +Y KGAD++++D L + +++ + T ++LN
Sbjct: 571 NNIRKRMSVIVRNP-EGKIRLYCKGADTILLDRLHHST---------QELLNTTMDHLNE 620
Query: 803 YAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATG 862
YA EGLRTL +A + L +E Y W + L+A + ++ E+ L +E N+ LLGAT
Sbjct: 621 YAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATA 680
Query: 863 IEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHD--EEVITLNATSQ 920
IED+LQ GVPETI+ L A ++IWVLTGDKQETAVNI Y+CK+L D E I T
Sbjct: 681 IEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVL 740
Query: 921 EACAALLDQCLCYVQSRGLQRAPEKTKGK---VSMRFSSLCPPSTSTASGRRPSLVIDGR 977
E L ++R ++ G + SS S A +LVI+G
Sbjct: 741 EVREELR-------KAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGH 793
Query: 978 SLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVS 1037
SLA+ALE ++E +FL A C++V+CCR TPLQK+ VV+LV+ KA+TLAIGDGANDVS
Sbjct: 794 SLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVS 853
Query: 1038 MIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNT 1097
MI+ A +GVGISGQEG+QAV+ASD++ +F++L+RLL++HG W Y R+ + YFFYKN
Sbjct: 854 MIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNF 913
Query: 1098 MFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLY 1157
F + FWF FFCGFSA T+ DQ+++ +N++++SLP L GV D+DVP + P+LY
Sbjct: 914 AFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLY 973
Query: 1158 KSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSN-------VDLFTWGTPIVTI 1210
+ GQ + R F+ +A + S++ F IPY + D+ D ++ + T
Sbjct: 974 EPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATS 1033
Query: 1211 ALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVAL-IYNASCATCYPPSNPY-WTMQAL 1268
++ + +G++T WT +N S+ ++F + +++ +P + Q
Sbjct: 1034 LVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNT 1093
Query: 1269 LGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLAR--QLTRKSPR 1316
L P +LT ++T V ++P + FR L+ + P R QL RK +
Sbjct: 1094 LAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQLVRKKQK 1143
Score = 308 bits (790), Expect = 2e-83
Identities = 164/412 (39%), Positives = 248/412 (60%), Gaps = 20/412 (4%)
Query: 48 ERRRRRGCAQH-----LADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPA 102
ERR R ++ A N +KT+KY +L+FLP NLFEQF AN YF+F+ +L +P
Sbjct: 46 ERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQ 105
Query: 103 VNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRF--- 159
+++ + P++ +L ITA +D +DY RH+SD+++N+ R+ + +N
Sbjct: 106 ISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNN-------RQSQVLINGILQQ 158
Query: 160 --WKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSE 217
W + VGD ++L N+ AD+LLLSSS+P GLC+IETA LDGETN+K RQ + SE
Sbjct: 159 EQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSE 218
Query: 218 LVSEFNPLTFTSVIECEKPNNDLSRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVG 277
L F + CE PNN L +F G + K L +N+LLRGC LRNT+ G
Sbjct: 219 LGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFP-LSNQNMLLRGCVLRNTEWCFG 277
Query: 278 IVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQE 337
+VI+AG +TK + N+ ++KR+ ++R MN VLW LVCM + A+G+ +W
Sbjct: 278 LVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGM 337
Query: 338 KKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQ 397
+ + Y+P + S + SF + II+L ++PISLYVS+E+++ YFIN D +
Sbjct: 338 RFQV-YLPWDEAVD-SAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKK 395
Query: 398 LYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEY 449
++ + + + R + E+LGQ++YIFSDKTGTLT+N MVF +C+++G Y
Sbjct: 396 MFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSY 447
>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
Length = 1192
Score = 424 bits (1091), Expect = e-118
Identities = 251/654 (38%), Positives = 388/654 (59%), Gaps = 36/654 (5%)
Query: 684 EQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRL-TFELLHTLGF 742
E+ S EL Y+ +SPDE ALV AAR + + R + +++E LG L T++LL L F
Sbjct: 480 EENSAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIE--ELGTLVTYQLLAFLDF 537
Query: 743 DSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNV 802
++ RKRMSV++R+P +I +Y+KGAD+++ + L P + V + S T ++L+
Sbjct: 538 NNTRKRMSVIVRNP-EGQIKLYSKGADTILFEKLHPSNEV---------LLSLTSDHLSE 587
Query: 803 YAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATG 862
+A EGLRTL IA R L + + W + +A ++ E +E + +E +L LLGAT
Sbjct: 588 FAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATA 647
Query: 863 IEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITL----NAT 918
+ED+LQ+GV ET++ L A ++IWVLTGDKQETA+NI YAC +L D + + NA
Sbjct: 648 VEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAV 707
Query: 919 SQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRS 978
Q L + Q+R + K + S+ T +G +L+I+G S
Sbjct: 708 EVREELRKAKQNL-FGQNRNFSNGHVVCEKKQQLELDSIVE---ETITGDY-ALIINGHS 762
Query: 979 LAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSM 1038
LA+ALE ++++ L LA C++V+CCR TPLQK+ VV+LV+ A+TLAIGDGANDVSM
Sbjct: 763 LAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSM 822
Query: 1039 IQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTM 1098
I+ A +GVGISGQEG+QAV+ASD++ +FRYL+RLL++HG W Y R+ + YFFYKN
Sbjct: 823 IKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFA 882
Query: 1099 FVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYK 1158
F + FWF FFCGFSA T+ DQW++ FN++++SLP L G+ D+DV + PQLYK
Sbjct: 883 FTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYK 942
Query: 1159 SGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYD-------SNVDLFTWGTPIVTIA 1211
GQ + R F+ + + SLV F IPY A+Y+ D ++ + T
Sbjct: 943 PGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSL 1002
Query: 1212 LLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVAL-IYNASCATCYPPSNPY-WTMQALL 1269
++ + + ++T WT++N + S+ ++F++ +++ +P P+ + L
Sbjct: 1003 VIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSL 1062
Query: 1270 GDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTR--KSPRRCSAP 1321
+L L+T VA+++P + FR L+ ++PT L+ Q+ R K+ ++ P
Sbjct: 1063 TQKCIWLVILLTTVASVMPVVAFRFLKVDLYPT---LSDQIRRWQKAQKKARPP 1113
Score = 311 bits (796), Expect = 4e-84
Identities = 167/411 (40%), Positives = 252/411 (61%), Gaps = 12/411 (2%)
Query: 60 ADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFIL 119
ADNR+ T+KY +L+FLP NLFEQF R AN YF+ + +L +P +++ + P++ ++
Sbjct: 29 ADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVLVI 88
Query: 120 AITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPA 179
+TA +D +DY RH+SD+++N+ V K N W + VGD ++L N+ A
Sbjct: 89 TMTAVKDATDDYFRHKSDNQVNNRQSEVLINS--KLQNEKWMNVKVGDIIKLENNQFVAA 146
Query: 180 DILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLT-FTSVIECEKPNN 238
D+LLLSSS+P GLC++ETA LDGETNLK R + SEL ++ + L F ++ CE PNN
Sbjct: 147 DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
Query: 239 DLSRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYK 298
L +F G I+ K L E ++LRGC LRNT G+VI+AG +TK + N+ ++K
Sbjct: 207 KLDKFMG-ILSWKDSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFK 265
Query: 299 RSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRY--QEKKSLFYVPKSDGSSLSPVT 356
R+ ++R MN VLW L+C+ + A+G+ +W + Q + LF+ ++G S V
Sbjct: 266 RTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFW---NEGEK-SSVF 321
Query: 357 AAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITE 416
+ +F + II+L ++PISLYVS+E+++ YFIN D ++Y R + E
Sbjct: 322 SGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNE 381
Query: 417 DLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYS--HDANAQRLARYQEAD 465
+LGQI+YIFSDKTGTLT+N M F+RC+++G Y HD Q+ QE +
Sbjct: 382 ELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKE 432
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 402 bits (1034), Expect = e-111
Identities = 238/641 (37%), Positives = 361/641 (56%), Gaps = 52/641 (8%)
Query: 684 EQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLT-FELLHTLGF 742
E+E ++ + Y+A SPDE ALV AA+ N V R D V ++ LG+ +ELL+ L F
Sbjct: 478 EREGDKII-YQAASPDEGALVRAAKQLNFVFTGRTPDSVIID--SLGQEERYELLNVLEF 534
Query: 743 DSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNV 802
S RKRMSV++R P + ++ +Y KGAD+V+ D L S K + T +L
Sbjct: 535 TSARKRMSVIVRTP-SGKLRLYCKGADTVIYDRLAETS----------KYKEITLKHLEQ 583
Query: 803 YAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATG 862
+A EGLRTLC A +S+ ++ W + A +S++N L +S +E NL LLGAT
Sbjct: 584 FATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATA 643
Query: 863 IEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEA 922
IED+LQD VPETI L +A ++IW+LTGDKQETA+NI ++CKLL + +I +N S +
Sbjct: 644 IEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDG 703
Query: 923 CAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYA 982
L + C L++ + +L+IDG++L YA
Sbjct: 704 TRETLSRH-CTTLGDALRKENDF-------------------------ALIIDGKTLKYA 737
Query: 983 LEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVA 1042
L + FL LA C++V+CCR +PLQKS VV++V+ ++K +TLAIGDGANDVSMIQ A
Sbjct: 738 LTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTA 797
Query: 1043 DVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGL 1102
VGVGISG EG+QA +SD+++ +F+YL+ LL++HG W Y+R++ +LY FYKN + +
Sbjct: 798 HVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYII 857
Query: 1103 LFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQN 1162
WF F GFS + ++W + +N++F+++PPL G+ +R +L P+LYK+ QN
Sbjct: 858 EIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQN 917
Query: 1163 MEEYRPRTFWFNMADAAFQSLVCFSIPYLAYY-------DSNVDLFTWGTPIVTIALLTF 1215
++ + FW + + F S++ F P A D G + T ++T
Sbjct: 918 ALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITV 977
Query: 1216 LLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQA--LLGDPV 1273
L G+ET WTW + I S+ L+ IY++ P P + +A L V
Sbjct: 978 CLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAI--PMAPDMSGEAAMLFSSGV 1035
Query: 1274 FYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRKS 1314
F++ L PVA+LL + ++ ++ F T + ++L KS
Sbjct: 1036 FWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAKS 1076
Score = 303 bits (775), Expect = 1e-81
Identities = 164/393 (41%), Positives = 238/393 (60%), Gaps = 8/393 (2%)
Query: 61 DNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILA 120
+N + T KY +++FLP+ L+ QF R AN +F+FIALL +P V+ L P+LFILA
Sbjct: 51 NNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILA 110
Query: 121 ITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPAD 180
+ A +++ ED RH++D+ +N V + V+ W++++VGD V ++ E PAD
Sbjct: 111 VAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVH--WEKVNVGDIVIIKGKEYIPAD 168
Query: 181 ILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDL 240
+LLSSS+P +C+IET+NLDGETNLK RQ + S++ + + + IECE PN L
Sbjct: 169 TVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHL 228
Query: 241 SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS 300
F G I D L + +LLRG LRNT V GIV+Y GH+TK + N++ P K S
Sbjct: 229 YDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLS 288
Query: 301 KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY 360
+ER N +L +L+ MSL +VG +W R+ K + S+
Sbjct: 289 NVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFG------L 342
Query: 361 SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ 420
+FLT II+ LIPISL V++E+VK Q YFIN D+ ++ E TD+ R N+ E+LGQ
Sbjct: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
Query: 421 IQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDA 453
++YIFSDKTGTLT N M F++CT++GV Y ++
Sbjct: 403 VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNS 435
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 402 bits (1034), Expect = e-111
Identities = 238/641 (37%), Positives = 361/641 (56%), Gaps = 52/641 (8%)
Query: 684 EQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLT-FELLHTLGF 742
E+E ++ + Y+A SPDE ALV AA+ N V R D V ++ LG+ +ELL+ L F
Sbjct: 493 EREGDKII-YQAASPDEGALVRAAKQLNFVFTGRTPDSVIID--SLGQEERYELLNVLEF 549
Query: 743 DSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNV 802
S RKRMSV++R P + ++ +Y KGAD+V+ D L S K + T +L
Sbjct: 550 TSARKRMSVIVRTP-SGKLRLYCKGADTVIYDRLAETS----------KYKEITLKHLEQ 598
Query: 803 YAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATG 862
+A EGLRTLC A +S+ ++ W + A +S++N L +S +E NL LLGAT
Sbjct: 599 FATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATA 658
Query: 863 IEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEA 922
IED+LQD VPETI L +A ++IW+LTGDKQETA+NI ++CKLL + +I +N S +
Sbjct: 659 IEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDG 718
Query: 923 CAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYA 982
L + C L++ + +L+IDG++L YA
Sbjct: 719 TRETLSRH-CTTLGDALRKENDF-------------------------ALIIDGKTLKYA 752
Query: 983 LEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVA 1042
L + FL LA C++V+CCR +PLQKS VV++V+ ++K +TLAIGDGANDVSMIQ A
Sbjct: 753 LTFGVRQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTA 812
Query: 1043 DVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGL 1102
VGVGISG EG+QA +SD+++ +F+YL+ LL++HG W Y+R++ +LY FYKN + +
Sbjct: 813 HVGVGISGNEGLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYII 872
Query: 1103 LFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQN 1162
WF F GFS + ++W + +N++F+++PPL G+ +R +L P+LYK+ QN
Sbjct: 873 EIWFAFVNGFSGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQN 932
Query: 1163 MEEYRPRTFWFNMADAAFQSLVCFSIPYLAYY-------DSNVDLFTWGTPIVTIALLTF 1215
++ + FW + + F S++ F P A D G + T ++T
Sbjct: 933 ALDFNTKVFWVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITV 992
Query: 1216 LLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQA--LLGDPV 1273
L G+ET WTW + I S+ L+ IY++ P P + +A L V
Sbjct: 993 CLKAGLETSYWTWFSHIAIWGSIALWVVFFGIYSSLWPAI--PMAPDMSGEAAMLFSSGV 1050
Query: 1274 FYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRKS 1314
F++ L PVA+LL + ++ ++ F T + ++L KS
Sbjct: 1051 FWMGLLFIPVASLLLDVVYKVIKRTAFKTLVDEVQELEAKS 1091
Score = 301 bits (771), Expect = 3e-81
Identities = 163/391 (41%), Positives = 236/391 (60%), Gaps = 8/391 (2%)
Query: 61 DNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILA 120
+N + T KY +++FLP+ L+ QF R AN +F+FIALL +P V+ L P+LFILA
Sbjct: 51 NNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLFILA 110
Query: 121 ITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPAD 180
+ A +++ ED RH++D+ +N V + V+ W+++ VG+ V++ E PAD
Sbjct: 111 VAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVH--WEKVAVGEIVKVTNGEHLPAD 168
Query: 181 ILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDL 240
++ LSSS+P +C+IET+NLDGETNLK RQ + S++ + + + IECE PN L
Sbjct: 169 LISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPNRHL 228
Query: 241 SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS 300
F G I D L + +LLRG LRNT V GIV+Y GH+TK + N++ P K S
Sbjct: 229 YDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPLKLS 288
Query: 301 KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY 360
+ER N +L +L+ MSL +VG +W R+ K + S+
Sbjct: 289 NVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFG------L 342
Query: 361 SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ 420
+FLT II+ LIPISL V++E+VK Q YFIN D+ ++ E TD+ R N+ E+LGQ
Sbjct: 343 NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQ 402
Query: 421 IQYIFSDKTGTLTENKMVFRRCTVSGVEYSH 451
++YIFSDKTGTLT N M F++CT++GV Y H
Sbjct: 403 VKYIFSDKTGTLTCNVMQFKKCTIAGVAYGH 433
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 393 bits (1009), Expect = e-109
Identities = 243/632 (38%), Positives = 346/632 (54%), Gaps = 51/632 (8%)
Query: 693 YEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSV 751
Y+A SPDEAALV A+ V R V +E +G+ TF +L+ L F S RKRMSV
Sbjct: 521 YQASSPDEAALVKGAKKLGFVFTARTPFSVIIEA--MGQEQTFGILNVLEFSSDRKRMSV 578
Query: 752 VIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTL 811
++R P + + +Y KGAD+V+ + L S K +T +L +A EGLRTL
Sbjct: 579 IVRTP-SGRLRLYCKGADNVIFERLSKDS----------KYMEETLCHLEYFATEGLRTL 627
Query: 812 CIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGV 871
C+A LS+ EY WL+ + EA + L++ + L + +E NL LLGAT IEDRLQ GV
Sbjct: 628 CVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGV 687
Query: 872 PETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCL 931
PETI+ L +A ++IWVLTGDKQETA+NI Y+C+L+ + +I L S +A A + Q
Sbjct: 688 PETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQ-- 745
Query: 932 CYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKNLEDKF 991
+ G E +L+IDG +L YAL + F
Sbjct: 746 -HCTDLGNLLGKENDV-----------------------ALIIDGHTLKYALSFEVRRSF 781
Query: 992 LFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQ 1051
L LA C++V+CCR +PLQKS +V +V+ ++KA+TLAIGDGANDV MIQ A VGVGISG
Sbjct: 782 LDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGN 841
Query: 1052 EGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCG 1111
EGMQA SD+A+ +F YLE+LL++HG W Y+R+ +LY FYKN + + WF F G
Sbjct: 842 EGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNG 901
Query: 1112 FSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTF 1171
FS + ++W + +N++F++LPP G+ +R +L PQLYK QN E + + F
Sbjct: 902 FSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVF 961
Query: 1172 WFNMADAAFQSLVCFSIPYLAYYDSNV-------DLFTWGTPIVTIALLTFLLHLGIETK 1224
W + +A SL+ F P A V D G + T ++T L G+ET
Sbjct: 962 WGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETT 1021
Query: 1225 TWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQA--LLGDPVFYLTCLMTP 1282
WT + + S+L + IY+ T P P QA +L F+L + P
Sbjct: 1022 AWTKFSHLAVWGSMLTWLVFFGIYSTIWPTI--PIAPDMRGQATMVLSSAHFWLGLFLVP 1079
Query: 1283 VAALLPRLFFRSLQGRVFPTQLQLARQLTRKS 1314
A L+ + +R+ + T L+ ++L KS
Sbjct: 1080 TACLIEDVAWRAAKHTCKKTLLEEVQELETKS 1111
Score = 292 bits (747), Expect = 2e-78
Identities = 159/391 (40%), Positives = 235/391 (60%), Gaps = 8/391 (2%)
Query: 61 DNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILA 120
DN++ T KY++L+FLP+ L+EQ R AN +F+FIALL +P V+ L P++ IL
Sbjct: 70 DNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLIIILT 129
Query: 121 ITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPAD 180
I +++ ED+ RH++D+ +N +V + WKE+ VGD V++ + PAD
Sbjct: 130 IAGIKEIVEDFKRHKADNAVNKKKTIVL--RNGMWHTIMWKEVAVGDIVKVVNGQYLPAD 187
Query: 181 ILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDL 240
++LLSSS+P +C++ETANLDGETNLK RQ + +++ + + + IECE PN L
Sbjct: 188 VVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGTIECEGPNRHL 247
Query: 241 SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS 300
F G + D L + +LLRG LRNT V GIV+Y GH+TK + N++ KRS
Sbjct: 248 YDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRS 307
Query: 301 KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY 360
+E+ N +L +L+ M+L S+ G W + EK +Y+ K D +S Y
Sbjct: 308 NVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKN--WYIKKMDTTS----DNFGY 361
Query: 361 SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ 420
+ LT II+ LIPISL V++E+VK Q FIN D +Y D+ R N+ E+LGQ
Sbjct: 362 NLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQ 421
Query: 421 IQYIFSDKTGTLTENKMVFRRCTVSGVEYSH 451
++Y+FSDKTGTLT N M F++C+++GV Y H
Sbjct: 422 VKYLFSDKTGTLTCNIMNFKKCSIAGVTYGH 452
>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
Length = 1251
Score = 381 bits (979), Expect = e-105
Identities = 243/729 (33%), Positives = 386/729 (52%), Gaps = 76/729 (10%)
Query: 687 SERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLG-RLTFELLHTLGFDSV 745
++ +L Y+A SPDE ALV AAR + + R + +++ LG T+ +L L F+S
Sbjct: 542 TDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITIS--ELGTERTYNVLAILDFNSD 599
Query: 746 RKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAA 805
RKRMS+++R P I +Y KGAD+V+ + L + +TQ+ L+++A
Sbjct: 600 RKRMSIIVRTP-EGNIKLYCKGADTVIYERLH----------RMNPTKQETQDALDIFAN 648
Query: 806 EGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIED 865
E LRTLC+ + + ++E+ W + + A + N +E L + +E +L LLGAT IED
Sbjct: 649 ETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIED 708
Query: 866 RLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAA 925
+LQDGVPETISKL +A ++IWVLTGDK+ETA NI +AC+LL D + + A
Sbjct: 709 KLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHAR 768
Query: 926 LLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDG--------- 976
+ +Q + +G V +F+ S G R +L+I G
Sbjct: 769 MENQ---------------RNRGGVYAKFAPPVQESFFPPGGNR-ALIITGSWLNEILLE 812
Query: 977 -------------------RSLAYALEKNLEDK-------FLFLAKQCRSVLCCRSTPLQ 1010
R + ++ LE K F+ LA +C +V+CCR TP Q
Sbjct: 813 KKTKRNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQ 872
Query: 1011 KSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYL 1070
K+MVV LV+ KA+TLAIGDGANDV+MI+ A +GVGISGQEGMQAVM+SD++ +FRYL
Sbjct: 873 KAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYL 932
Query: 1071 ERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLF 1130
+RLL++HG W Y R+ + YFFYKN F + FW+ FF G+SA T + W++ +N+L+
Sbjct: 933 QRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLY 992
Query: 1131 SSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPY 1190
+SLP L+ G+LD+DV + L P LY GQ + + F+ ++ S++ F IP
Sbjct: 993 TSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPL 1052
Query: 1191 LAYY-------DSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFT 1243
AY ++ D ++ I + ++T +G++T WT++N + S+ L+F
Sbjct: 1053 GAYLQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFG 1112
Query: 1244 VAL-IYNASCATCYPPSNPY-WTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFP 1301
+ ++A +P + + T L P +LT ++T LLP + R L ++P
Sbjct: 1113 IMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWP 1172
Query: 1302 TQLQLARQLTR--KSPRRCSAPKETFAQGRLPKDSGTEHSSGRTVKTSVPLSQPSWHTQQ 1359
++ ++ + K+ + ++ F +G + S S R + + +
Sbjct: 1173 SESDKIQKHRKRLKAEEQWQRRQQVFRRGVSTRRSAYAFSHQRGYADLISSGRSIRKKRS 1232
Query: 1360 PVCSLEASG 1368
P+ ++ A G
Sbjct: 1233 PLDAIVADG 1241
Score = 313 bits (802), Expect = 8e-85
Identities = 170/399 (42%), Positives = 243/399 (60%), Gaps = 8/399 (2%)
Query: 60 ADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFIL 119
A+N +KT KY +F+P NLFEQF R AN+YF+ + +L VP ++ L P+L +L
Sbjct: 93 ANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLVVL 152
Query: 120 AITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPA 179
+TA +DL +D +RH+ D +IN+ C V K WKEI VGD +RL+ N+ PA
Sbjct: 153 GVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAK--WKEIQVGDVIRLKKNDFVPA 210
Query: 180 DILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPL-TFTSVIECEKPNN 238
DILLLSSS+P+ LC++ETA LDGETNLK + + + + + L TF IECE+PNN
Sbjct: 211 DILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNN 270
Query: 239 DLSRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYK 298
L +F G + N L + +LLRGC +RNTD G+VI+AG +TK + N+ R+K
Sbjct: 271 RLDKFTGTLFWRN-TSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKTRFK 329
Query: 299 RSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAA 358
R+K++ MN V ++L+ +S A+GH W Q S +Y+ DG +P
Sbjct: 330 RTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYW--EAQVGNSSWYL--YDGEDDTPSYRG 385
Query: 359 VYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDL 418
F IIVL ++PISLYVS+E+++ Q +FIN D+Q+Y E D+ + R + E L
Sbjct: 386 FLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQL 445
Query: 419 GQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQR 457
GQI YIFSDKTGTLT+N M F++C ++G Y +A +
Sbjct: 446 GQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQ 484
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 355 bits (912), Expect = 1e-97
Identities = 247/741 (33%), Positives = 381/741 (51%), Gaps = 82/741 (11%)
Query: 614 TPSCLTSGCSSIGSLA-ANKSSH-KLGSSFPSTPSSDGMLLRLEERLGQPTSAIASNGYS 671
TP S + SL+ N SH SSF ++P ++ L++ + + S + S
Sbjct: 442 TPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQIS 501
Query: 672 S-QAD-----NWASELAQEQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVE 725
+ Q D W S LA Q L Y A SPDE ALV AA V + + + ++E
Sbjct: 502 NVQTDCTGDGPWQSNLAPSQ-----LEYYASSPDEKALVEAAARIGIVFIG--NSEETME 554
Query: 726 LPHLGRLT-FELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDA 784
+ LG+L ++LLH L FDS R+RMSV+++ P +++ ++ KGA+S +L C +
Sbjct: 555 VKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKL-LFAKGAES---SILPKCIGGEI 610
Query: 785 RGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELL 844
KT+ +++ +A +GLRTLCIA R + +EY + EA ++L+ EE L
Sbjct: 611 E---------KTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKL 661
Query: 845 FQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACK 904
+E +L LLGAT +EDRLQD V ETI LR AG+++WVLTGDK ETAV+++ +C
Sbjct: 662 AAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCG 721
Query: 905 LLDHDEEVITL-NATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTS 963
++ L N S CA L Q A T+ V
Sbjct: 722 HFHRTMNILELINQKSDSECAEQLRQL-----------ARRITEDHVIQH---------- 760
Query: 964 TASGRRPSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVR-SKL 1022
LV+DG SL+ AL ++ E F+ + + C +VLCCR PLQK+ V++L++ S
Sbjct: 761 -------GLVVDGTSLSLALREH-EKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPE 812
Query: 1023 KAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCY 1082
K +TLA+GDGANDVSMIQ A VG+GI G+EG QA SD+A+ +F++L +LL +HGH+ Y
Sbjct: 813 KPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYY 872
Query: 1083 SRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLD 1142
R+A +V YFFYKN F+ F +QF+C FS T+ D YL +N+ F+SLP L+ +L+
Sbjct: 873 IRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLE 932
Query: 1143 RDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDS------ 1196
+ V +VL P LY+ +TF + +++ FS ++ ++ S
Sbjct: 933 QHVDPHVLQNKPTLYRDISKNRLLSIKTF-------LYWTILGFSHAFIFFFGSYLLIGK 985
Query: 1197 ------NVDLF---TWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALI 1247
N +F T+GT + T+ ++T + + +ET WTW+N + S++ +F +L
Sbjct: 986 DTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLF 1045
Query: 1248 YNASCATCYPPSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLA 1307
Y N Y+ LL + ++ V L + + + PT + A
Sbjct: 1046 YGGILWPFLGSQNMYFVFIQLLSSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKA 1105
Query: 1308 RQLTRKSPRRCSAPKETFAQG 1328
+ + +C F +G
Sbjct: 1106 QLTETNAGIKCLDSMCCFPEG 1126
Score = 281 bits (718), Expect = 4e-75
Identities = 182/524 (34%), Positives = 283/524 (54%), Gaps = 26/524 (4%)
Query: 57 QHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVL 116
Q DNR+ ++KYT+ +F+PKNLFEQF R AN YF+ I L+ + P + P+
Sbjct: 37 QKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPT-SPVTSGLPLF 95
Query: 117 FILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEI 176
F++ +TA + +ED+ RH SD+++N G V+ V K I VGD VR+ +EI
Sbjct: 96 FVITVTAIKQGYEDWLRHNSDNEVN--GAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEI 153
Query: 177 FPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKP 236
FPAD++LLSS DG CH+ TA+LDGETNLK V + L + N T +VIEC++P
Sbjct: 154 FPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQP 213
Query: 237 NNDLSRFRGCIIHDNGKKA---GLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNS 293
DL RF G +I + L E+LLLRG L+NT + G+ +Y G ETK LN
Sbjct: 214 EADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYK 273
Query: 294 GPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEK-KSLFYVPKSDGS-S 351
KRS +E+ MN ++ +++L+ ++ S + + W+ +EK +Y K++ +
Sbjct: 274 SKSQKRSAVEKSMNTFLIIYLVILISEAVISTILK--YTWQAEEKWDEPWYNQKTEHQRN 331
Query: 352 LSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRA 411
S + + FL +++ +IPISLYV++E+ K +FI D+ LY EE+D + Q
Sbjct: 332 SSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNT 391
Query: 412 LNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEV 471
++ E+LGQ++Y+F+DKTGTLTEN+M FR C+++G++Y + N + + DS E
Sbjct: 392 SDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKY-QEINGRLVPEGPTPDSSE--- 447
Query: 472 VPRGGSVSQRGSIGSHQSVRVVHRTQSTKSHRRTGSRAE-AKRASMLSK-----HTAFSS 525
G++S S+ SH + + H T S+ + E K + K HT S
Sbjct: 448 ----GNLSYLSSL-SHLN-NLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQIS 501
Query: 526 PMEKDITPDPKLLEKVSECDKSLAVARHQEHLLAHLSPELSDVF 569
++ D T D ++ + E L + + VF
Sbjct: 502 NVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVF 545
>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
Length = 1119
Score = 345 bits (885), Expect = 2e-94
Identities = 211/621 (33%), Positives = 338/621 (54%), Gaps = 46/621 (7%)
Query: 690 ELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLTFELLHTLGFDSVRKRM 749
EL Y + SPDE ALV A+ Y + + + VE +ELLHTL FD+VR+RM
Sbjct: 491 ELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRM 550
Query: 750 SVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLR 809
SV+++ D I ++ KGADS V +Q H+ ++ T+ ++ A +G R
Sbjct: 551 SVIVKTQEGD-ILLFCKGADSAVFPRVQ---------NHEIEL---TKVHVERNAMDGYR 597
Query: 810 TLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQD 869
TLC+A + ++ ++Y + +EA+ +L++ EE + + +ETN++L+GAT +ED+LQD
Sbjct: 598 TLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQD 657
Query: 870 GVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLD- 928
ETI L AGL++WVLTGDK ETA + YAC+L + E++ L + E D
Sbjct: 658 QAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDR 717
Query: 929 --QCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEK- 985
+ L + + L P+ T+ + + L+IDG +L+ L
Sbjct: 718 LHELLIEYRKKLLHEFPKSTRSF-----------KKAWTEHQEYGLIIDGSTLSLILNSS 766
Query: 986 ------NLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRS-KLKAMTLAIGDGANDVSM 1038
N + FL + +C +VLCCR PLQK+ +V++V++ K +TL+IGDGANDVSM
Sbjct: 767 QDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSM 826
Query: 1039 IQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTM 1098
I + VG+GI G+EG QA SD++VPKF++L++LL+ HGH Y R+A++V YFFYKN
Sbjct: 827 ILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLC 886
Query: 1099 FVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYK 1158
F+ F +QFFCGFS + D YL +N+ F+SLP L +L++ + + L ++P+LY
Sbjct: 887 FILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYM 946
Query: 1159 --SGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVD-------LFTWGTPIVT 1209
SG M + P +W + AAF+ V F Y + ++++ +T+GT + T
Sbjct: 947 KISGNAMLQLGPFLYWTFL--AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFT 1004
Query: 1210 IALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQALL 1269
+ + T L L ++T+ WTW+N S+ + + + Y+ +L
Sbjct: 1005 VLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQML 1064
Query: 1270 GDPVFYLTCLMTPVAALLPRL 1290
+L ++ +L P +
Sbjct: 1065 SSVSTWLAIILLIFISLFPEI 1085
Score = 264 bits (675), Expect = 4e-70
Identities = 151/401 (37%), Positives = 233/401 (58%), Gaps = 13/401 (3%)
Query: 56 AQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPV 115
AQ DNR+ ++KYTL +FLPKNLFEQF R AN YF+ I L+ V P + P+
Sbjct: 40 AQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ-VTVDTPTSPVTSGLPL 98
Query: 116 LFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNE 175
F++ +TA + +ED+ RHR+D+++N V+ E K V + ++I VGD V ++ +E
Sbjct: 99 FFVITVTAIKQGYEDWLRHRADNEVNK--STVYIIENAKRVRKESEKIKVGDVVEVQADE 156
Query: 176 IFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEK 235
FP D++LLSS DG C++ TA+LDGE+N K VR L + + T + IECE+
Sbjct: 157 TFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQ 216
Query: 236 PNNDLSRFRGCI-IHDNGKKA---GLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLN 291
P DL +F G I I+ N +A L ENLLL+G TL+NT+ + G+ +Y G ETK LN
Sbjct: 217 PQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALN 276
Query: 292 NSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWR---YQEKKSLFYVPKSD 348
G KRS +E+ +N ++ V L + ++ + ++W+ Y ++ + +
Sbjct: 277 YQGKSQKRSAVEKSINAFLI--VYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKE 334
Query: 349 GSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQ 408
+L V FL+ +++ +IP+S+YV++E+ K +FI+ D YDEE +
Sbjct: 335 RETLK-VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGAL 393
Query: 409 CRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEY 449
++ E+LGQ+ Y+F+DKTGTLTEN M F C + G +Y
Sbjct: 394 VNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
Length = 1132
Score = 345 bits (885), Expect = 2e-94
Identities = 211/621 (33%), Positives = 338/621 (54%), Gaps = 46/621 (7%)
Query: 690 ELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLTFELLHTLGFDSVRKRM 749
EL Y + SPDE ALV A+ Y + + + VE +ELLHTL FD+VR+RM
Sbjct: 491 ELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRM 550
Query: 750 SVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLR 809
SV+++ D I ++ KGADS V +Q H+ ++ T+ ++ A +G R
Sbjct: 551 SVIVKTQEGD-ILLFCKGADSAVFPRVQ---------NHEIEL---TKVHVERNAMDGYR 597
Query: 810 TLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQD 869
TLC+A + ++ ++Y + +EA+ +L++ EE + + +ETN++L+GAT +ED+LQD
Sbjct: 598 TLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQD 657
Query: 870 GVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLD- 928
ETI L AGL++WVLTGDK ETA + YAC+L + E++ L + E D
Sbjct: 658 QAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDR 717
Query: 929 --QCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEK- 985
+ L + + L P+ T+ + + L+IDG +L+ L
Sbjct: 718 LHELLIEYRKKLLHEFPKSTRSF-----------KKAWTEHQEYGLIIDGSTLSLILNSS 766
Query: 986 ------NLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRS-KLKAMTLAIGDGANDVSM 1038
N + FL + +C +VLCCR PLQK+ +V++V++ K +TL+IGDGANDVSM
Sbjct: 767 QDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSM 826
Query: 1039 IQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTM 1098
I + VG+GI G+EG QA SD++VPKF++L++LL+ HGH Y R+A++V YFFYKN
Sbjct: 827 ILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLC 886
Query: 1099 FVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYK 1158
F+ F +QFFCGFS + D YL +N+ F+SLP L +L++ + + L ++P+LY
Sbjct: 887 FILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYM 946
Query: 1159 --SGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVD-------LFTWGTPIVT 1209
SG M + P +W + AAF+ V F Y + ++++ +T+GT + T
Sbjct: 947 KISGNAMLQLGPFLYWTFL--AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFT 1004
Query: 1210 IALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQALL 1269
+ + T L L ++T+ WTW+N S+ + + + Y+ +L
Sbjct: 1005 VLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQML 1064
Query: 1270 GDPVFYLTCLMTPVAALLPRL 1290
+L ++ +L P +
Sbjct: 1065 SSVSTWLAIILLIFISLFPEI 1085
Score = 264 bits (675), Expect = 4e-70
Identities = 151/401 (37%), Positives = 233/401 (58%), Gaps = 13/401 (3%)
Query: 56 AQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPV 115
AQ DNR+ ++KYTL +FLPKNLFEQF R AN YF+ I L+ V P + P+
Sbjct: 40 AQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ-VTVDTPTSPVTSGLPL 98
Query: 116 LFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNE 175
F++ +TA + +ED+ RHR+D+++N V+ E K V + ++I VGD V ++ +E
Sbjct: 99 FFVITVTAIKQGYEDWLRHRADNEVNK--STVYIIENAKRVRKESEKIKVGDVVEVQADE 156
Query: 176 IFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEK 235
FP D++LLSS DG C++ TA+LDGE+N K VR L + + T + IECE+
Sbjct: 157 TFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQ 216
Query: 236 PNNDLSRFRGCI-IHDNGKKA---GLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLN 291
P DL +F G I I+ N +A L ENLLL+G TL+NT+ + G+ +Y G ETK LN
Sbjct: 217 PQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALN 276
Query: 292 NSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWR---YQEKKSLFYVPKSD 348
G KRS +E+ +N ++ V L + ++ + ++W+ Y ++ + +
Sbjct: 277 YQGKSQKRSAVEKSINAFLI--VYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKE 334
Query: 349 GSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQ 408
+L V FL+ +++ +IP+S+YV++E+ K +FI+ D YDEE +
Sbjct: 335 RETLK-VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGAL 393
Query: 409 CRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEY 449
++ E+LGQ+ Y+F+DKTGTLTEN M F C + G +Y
Sbjct: 394 VNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 344 bits (882), Expect = 4e-94
Identities = 222/647 (34%), Positives = 347/647 (53%), Gaps = 49/647 (7%)
Query: 693 YEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLT-FELLHTLGFDSVRKRMSV 751
Y + SPDE ALV + + RL D L + FELL L FDSVR+RMSV
Sbjct: 504 YISSSPDEVALVEGVQRLGFTYL-RLKDNYMEILNRENHIERFELLEILSFDSVRRRMSV 562
Query: 752 VIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTL 811
+++ T EI ++ KGADS + + R R ++ A EGLRTL
Sbjct: 563 IVKSA-TGEIYLFCKGADSSIFPRVIEGKVDQIRARVERN------------AVEGLRTL 609
Query: 812 CIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGV 871
C+A + L +EEY + A+ +L++ E+ L ++ ++E +L LLGAT +EDRLQ+
Sbjct: 610 CVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKA 669
Query: 872 PETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCL 931
+TI L++AG+++WVLTGDK ETA YACKL + +++ L T++ L L
Sbjct: 670 ADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLEL--TTKRIEEQSLHDVL 727
Query: 932 CYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEK------ 985
+ L+ + T+ +S +A + L+IDG +L+ ++
Sbjct: 728 FELSKTVLRHSGSLTRDNLS----------GLSADMQDYGLIIDGAALSLIMKPREDGSS 777
Query: 986 -NLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVR-SKLKAMTLAIGDGANDVSMIQVAD 1043
N + FL + + C +VLCCR PLQK+ +VKL++ SK +TLAIGDGANDVSMI A
Sbjct: 778 GNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAH 837
Query: 1044 VGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLL 1103
VG+G+ G+EG QA SD+A+PKF++L+++L++HGH+ Y R++ +V YFFYKN F+
Sbjct: 838 VGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQ 897
Query: 1104 FWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNM 1163
F +QFFCGFS T+ D YL +N+ F+SLP L+ ++++ V +VL +P LY+
Sbjct: 898 FLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKN 957
Query: 1164 EEYRPRTFWFNMADAAFQSLVCFSIPYLAYYD----SNVDLF---TWGTPIVTIALLTFL 1216
R R F + F +LV F Y + + SN +F T+GT + T+ + T
Sbjct: 958 ALLRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVT 1017
Query: 1217 LHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQALLGDPVFYL 1276
L L ++T WTW+N S+L + +L++ Y+ +L +L
Sbjct: 1018 LKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWL 1077
Query: 1277 TCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRKSPRRCSAPKE 1323
++ +LLP + + L +++PT T + C+ P++
Sbjct: 1078 AIVLLVTISLLPDVLKKVLCRQLWPT-------ATERVQNGCAQPRD 1117
Score = 255 bits (651), Expect = 3e-67
Identities = 149/422 (35%), Positives = 229/422 (54%), Gaps = 23/422 (5%)
Query: 33 PPPGAEDPAAGAAKGERRRRRGCAQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFV 92
PPPGAE Q DNR+ ++KYT +F+PKNLFEQF R AN YF+
Sbjct: 33 PPPGAE--------------AYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFL 78
Query: 93 FIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREE 152
I L+ + P + P+ F++ +TA + +ED+ RH++D+ +N C V +
Sbjct: 79 IIFLVQLIIDTPT-SPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQ--CPVHFIQH 135
Query: 153 KKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVV 212
K V + +++ VGD V ++ +E FP D++ LSS+ DG CH+ TA+LDGE++ K V
Sbjct: 136 GKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAV 195
Query: 213 RGFSELVSEFNPLTFTSVIECEKPNNDLSRFRGCI-----IHDNGKKAGLYKENLLLRGC 267
+ +E + + IECE+P DL +F G I ++D + L ENLLLRG
Sbjct: 196 QDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRP-LGSENLLLRGA 254
Query: 268 TLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVG 327
TL+NT+ + G+ IY G ETK LN KRS +E+ MN ++ + +L+ +L + V
Sbjct: 255 TLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVL 314
Query: 328 HGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKAC 387
+W + + + A FL +++ +IP+S+YV++E+ K
Sbjct: 315 KYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFL 374
Query: 388 QVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGV 447
YFI D ++DEET ++ E+LGQ++YIF+DKTGTLTEN M F+ C + G
Sbjct: 375 GSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGH 434
Query: 448 EY 449
Y
Sbjct: 435 VY 436
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 343 bits (879), Expect = 9e-94
Identities = 219/626 (34%), Positives = 340/626 (54%), Gaps = 42/626 (6%)
Query: 693 YEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLT-FELLHTLGFDSVRKRMSV 751
Y + SPDE ALV + + RL D L + FELL L FDSVR+RMSV
Sbjct: 504 YISSSPDEVALVEGVQRLGFTYL-RLKDNYMEILNRENHIERFELLEILSFDSVRRRMSV 562
Query: 752 VIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTL 811
+++ T EI ++ KGADS + + R R ++ A EGLRTL
Sbjct: 563 IVKSA-TGEIYLFCKGADSSIFPRVIEGKVDQIRARVERN------------AVEGLRTL 609
Query: 812 CIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGV 871
C+A + L +EEY + A+ +L++ E+ L ++ ++E +L LLGAT +EDRLQ+
Sbjct: 610 CVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKA 669
Query: 872 PETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCL 931
+TI L++AG+++WVLTGDK ETA YACKL + +++ L T++ L L
Sbjct: 670 ADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLEL--TTKRIEEQSLHDVL 727
Query: 932 CYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEK------ 985
+ L+ + T+ +S +A + L+IDG +L+ ++
Sbjct: 728 FELSKTVLRHSGSLTRDNLS----------GLSADMQDYGLIIDGAALSLIMKPREDGSS 777
Query: 986 -NLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVR-SKLKAMTLAIGDGANDVSMIQVAD 1043
N + FL + + C +VLCCR PLQK+ +VKL++ SK +TLAIGDGANDVSMI A
Sbjct: 778 GNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAH 837
Query: 1044 VGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLL 1103
VG+G+ G+EG QA SD+A+PKF++L+++L++HGH+ Y R++ +V YFFYKN F+
Sbjct: 838 VGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQ 897
Query: 1104 FWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNM 1163
F +QFFCGFS T+ D YL +N+ F+SLP L+ ++++ V +VL +P LY+
Sbjct: 898 FLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKN 957
Query: 1164 EEYRPRTFWFNMADAAFQSLVCFSIPYLAYYD----SNVDLF---TWGTPIVTIALLTFL 1216
R R F + F +LV F Y + + SN +F T+GT + T+ + T
Sbjct: 958 ALLRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVT 1017
Query: 1217 LHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQALLGDPVFYL 1276
L L ++T WTW+N S+L + +L++ Y+ +L +L
Sbjct: 1018 LKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWL 1077
Query: 1277 TCLMTPVAALLPRLFFRSLQGRVFPT 1302
++ +LLP + + L +++PT
Sbjct: 1078 AIVLLVTISLLPDVLKKVLCRQLWPT 1103
Score = 255 bits (651), Expect = 3e-67
Identities = 149/422 (35%), Positives = 229/422 (54%), Gaps = 23/422 (5%)
Query: 33 PPPGAEDPAAGAAKGERRRRRGCAQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFV 92
PPPGAE Q DNR+ ++KYT +F+PKNLFEQF R AN YF+
Sbjct: 33 PPPGAE--------------AYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFL 78
Query: 93 FIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREE 152
I L+ + P + P+ F++ +TA + +ED+ RH++D+ +N C V +
Sbjct: 79 IIFLVQLIIDTPT-SPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQ--CPVHFIQH 135
Query: 153 KKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVV 212
K V + +++ VGD V ++ +E FP D++ LSS+ DG CH+ TA+LDGE++ K V
Sbjct: 136 GKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAV 195
Query: 213 RGFSELVSEFNPLTFTSVIECEKPNNDLSRFRGCI-----IHDNGKKAGLYKENLLLRGC 267
+ +E + + IECE+P DL +F G I ++D + L ENLLLRG
Sbjct: 196 QDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRP-LGSENLLLRGA 254
Query: 268 TLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVG 327
TL+NT+ + G+ IY G ETK LN KRS +E+ MN ++ + +L+ +L + V
Sbjct: 255 TLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVL 314
Query: 328 HGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKAC 387
+W + + + A FL +++ +IP+S+YV++E+ K
Sbjct: 315 KYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFL 374
Query: 388 QVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGV 447
YFI D ++DEET ++ E+LGQ++YIF+DKTGTLTEN M F+ C + G
Sbjct: 375 GSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGH 434
Query: 448 EY 449
Y
Sbjct: 435 VY 436
>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
Length = 1300
Score = 330 bits (847), Expect = 5e-90
Identities = 224/636 (35%), Positives = 331/636 (52%), Gaps = 99/636 (15%)
Query: 665 IASNGYSSQADNWA------SELAQEQESER--ELRYEAESPDEAALVYAARAYNCVLVE 716
+ +NG + + W + + +E ER +L Y+A SPDE ALV AAR + V +
Sbjct: 553 VRTNGDEAVREFWRLLAICHTVMVRESPRERPDQLLYQAASPDEGALVTAARNFGYVFLS 612
Query: 717 RLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDL 775
R D V++ LG +++L + F+S RKRMSV++R P I +YTKGAD+V+ +
Sbjct: 613 RTQDTVTIM--ELGEERVYQVLAIMDFNSTRKRMSVLVRKP-EGAICLYTKGADTVIFER 669
Query: 776 LQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAES 835
L +++ T+ L +A E LRTLC+A R ++++ Y W Q H EA
Sbjct: 670 LHRRGAMEFA----------TEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQEASL 719
Query: 836 SLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQET 895
L+N + L Q LLGAT IEDRLQDGVPETI L+++ ++IWVLTGDKQET
Sbjct: 720 LLQNRAQALQQ----------LLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDKQET 769
Query: 896 AVNIAYACKLL--------------------DHDEEVITLNATSQEACAALLDQCLCYVQ 935
AVNI +AC+LL ++ ++T + SQ A +++
Sbjct: 770 AVNIGFACELLSENMLILEEKEISRILETYWENSNNLLTRESLSQVKLALVINGDFLDKL 829
Query: 936 SRGLQRAPEKTKGKVSM------------------RFSSLC--------PPSTSTASGRR 969
L++ P V+M R S LC P + RR
Sbjct: 830 LVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAPPAQDSRARR 889
Query: 970 PSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAI 1029
S V+ R+ F+ LA +C++V+CCR TP QK+++V LV+ + +TLAI
Sbjct: 890 SSEVLQERA------------FVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAI 937
Query: 1030 GDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMV 1089
GDGAND++MI+ ADVGVG++GQEGMQAV SDF + +F +L+RLL++HG W Y R+ +
Sbjct: 938 GDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFL 997
Query: 1090 LYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANV 1149
YFFYK+ + + WF + GF+ + + W+L FNLL+S+LP L G+ ++DV A
Sbjct: 998 RYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQ 1057
Query: 1150 LLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYD-----SNVDLFTWG 1204
L P+LY GQ E + F +A SLV F + D S D ++
Sbjct: 1058 SLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWISRDTAGPASFSDHQSFA 1117
Query: 1205 TPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLL 1240
+ LL+ + + + K WT L C ++LL
Sbjct: 1118 VVVALSCLLSITMEVILIIKYWTAL----CVATILL 1149
Score = 273 bits (699), Expect = 7e-73
Identities = 152/395 (38%), Positives = 235/395 (59%), Gaps = 8/395 (2%)
Query: 62 NRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAI 121
N ++T KY SFLP NL+EQFHR +N++F+ I +L +P ++ P++ +L I
Sbjct: 136 NVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMVCLLFI 195
Query: 122 TAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADI 181
A RDL +D RH+SD IN+ C + K + + W+++ VGD V LR + I PAD+
Sbjct: 196 RATRDLVDDMGRHKSDRAINNRPCQILMG--KSFKQKKWQDLCVGDVVCLRKDNIVPADM 253
Query: 182 LLLSSSDPDGLCHIETANLDGETNLKRRQVVR-GFSELVSEFNPLTFTSVIECEKPNNDL 240
LLL+S++P LC++ET ++DGETNLK RQ + EL + +F + CE PN+ +
Sbjct: 254 LLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPNSRM 313
Query: 241 SRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRS 300
F GC+ N KK L NLLLRGC +RNTD G+VIYAG +TK + N KR+
Sbjct: 314 HHFVGCL-EWNDKKYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGKIHLKRT 372
Query: 301 KLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVY 360
KL+ MN V+ + +V + L A G G + +++ +Y+ GSS++ + +
Sbjct: 373 KLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHH--YYLSGVHGSSVA--AESFF 428
Query: 361 SFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQ 420
F + +I+L V IP+S+++ E + FI+ D+Q+Y + D + R+ ++ + LGQ
Sbjct: 429 VFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLNDHLGQ 488
Query: 421 IQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANA 455
++YIFSDKTGTLT+N + F +C +SG Y D+ A
Sbjct: 489 VEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEA 523
>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
Length = 387
Score = 241 bits (614), Expect = 5e-63
Identities = 134/342 (39%), Positives = 200/342 (58%), Gaps = 20/342 (5%)
Query: 48 ERRRRRGCAQH-----LADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPA 102
ERR R ++ A N +KT+KY +L+FLP NLFEQF AN YF+F+ +L +P
Sbjct: 13 ERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQ 72
Query: 103 VNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRF--- 159
+++ + P++ +L ITA +D +DY RH+SD+++N+ R+ + +N
Sbjct: 73 ISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNN-------RQSQVLINGILQQ 125
Query: 160 --WKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSE 217
W + VGD ++L N+ AD+LLLSSS+P GLC+IETA LDGETN+K RQ + SE
Sbjct: 126 EQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSE 185
Query: 218 LVSEFNPLTFTSVIECEKPNNDLSRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVG 277
L F + CE PNN L +F G ++ K L +N+LLRGC LRNT+ G
Sbjct: 186 LGDISKLAKFDGEVICEPPNNKLDKFSG-TLYWKENKFPLSNQNMLLRGCVLRNTEWCFG 244
Query: 278 IVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQE 337
+VI+AG +TK + N+ ++KR+ ++R MN VLW LVCM + A+G+ +W
Sbjct: 245 LVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGM 304
Query: 338 KKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYV 379
+ + Y+P + S + SF + II+L ++PISLYV
Sbjct: 305 RFQV-YLPWDEAVD-SAFFSGFLSFWSYIIILNTVVPISLYV 344
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 235 bits (599), Expect = 3e-61
Identities = 168/568 (29%), Positives = 276/568 (48%), Gaps = 58/568 (10%)
Query: 662 TSAIASNGYSSQADNWASELAQEQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQ 721
T SNG + QA+ A++Q + Y+A SPDE ALV + LV R
Sbjct: 470 TPVYESNGVTDQAE------AEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSS 523
Query: 722 VSVELPHLGRLTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSS 781
+ + P L F +L F KRM +++R T EI Y KGAD V+ ++Q
Sbjct: 524 MQLRTPGDQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQ---- 579
Query: 782 VDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSE 841
+ + + N A EGLR L +AK+ L++E+Y + +++A+ S+ +
Sbjct: 580 ------YNDWLEEECGNM----AREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRS 629
Query: 842 ELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAY 901
+ LE + LL TG+ED+LQ V T+ LR AG+++W+LTGDK ETA A
Sbjct: 630 LKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAK 689
Query: 902 ACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPS 961
L+ ++++ + A +++ +R + C
Sbjct: 690 NAHLVTRNQDIHVFRLVTNRGEA--------HLELNAFRRKHD-------------C--- 725
Query: 962 TSTASGRRPSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSK 1021
+LVI G SL L K E +F+ LA QC +V+CCR P QK+ +V+L++ +
Sbjct: 726 ---------ALVISGDSLEVCL-KYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQER 775
Query: 1022 LKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWC 1081
+T A+GDG NDVSMIQ +D GVG+ G+EG QA +A+DF++ +F++L RLL++HG
Sbjct: 776 TGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNS 835
Query: 1082 YSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVL 1141
Y R A + + +++ + F F++ + + +I ++ +++ P+ + VL
Sbjct: 836 YKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMF-PVFSLVL 894
Query: 1142 DRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLF 1201
D+DV + V + P+LYK +TF + + +Q L + V +
Sbjct: 895 DKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHIV 954
Query: 1202 TWGTPIVTIALLTFLLHLGIETKTWTWL 1229
T +LT LL + + +TW WL
Sbjct: 955 AIS---FTSLILTELLMVALTIQTWHWL 979
Score = 159 bits (402), Expect = 2e-38
Identities = 118/403 (29%), Positives = 192/403 (47%), Gaps = 42/403 (10%)
Query: 57 QHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVL 116
Q N + KY +FLP LF QF N+YF+ +A FVP + P+
Sbjct: 51 QRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLG 110
Query: 117 FILAITAFRDLWEDYSRHRSDHKINHLGCLVFSR-EEKKYVNRFWKEIHVGDFVRLRCNE 175
F+LA+T R+ E+ + D ++N V+SR + V I VGD + + N+
Sbjct: 111 FVLAVTVIREAVEEIRCYVRDKEVNSQ---VYSRLTARGTVKVKSSNIQVGDLIIVEKNQ 167
Query: 176 IFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEK 235
PAD++ L +S+ +G C + T LDGET+ K R V L + + L S + E+
Sbjct: 168 RVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEE 227
Query: 236 PNNDLSRFRGCIIHDNGK---KAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNN 292
PN D+ F G ++ L EN L G T+ + VVG+V+Y G E ++++N
Sbjct: 228 PNIDIHNFVGTFTREDSDPPISESLSIENTLWAG-TVVASGTVVGVVLYTGRELRSVMNT 286
Query: 293 SGPRYKRSKLERQMNC--DVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGS 350
S PR K + ++NC +L+ L++V + + A+ H W Q
Sbjct: 287 SNPRSKIGLFDLEVNCLTKILFGALVVVSL-VMVALQHFAGRWYLQ-------------- 331
Query: 351 SLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCR 410
+ +++ +IPISL V++++ K + I +D ++ R
Sbjct: 332 -----------IIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI------PGTVVR 374
Query: 411 ALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDA 453
+ I E LG+I Y+ +DKTGTLT+N+M+F+R + V Y D+
Sbjct: 375 SSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDS 417
>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
Length = 1147
Score = 233 bits (595), Expect = 8e-61
Identities = 169/548 (30%), Positives = 266/548 (48%), Gaps = 52/548 (9%)
Query: 682 AQEQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLTFELLHTLG 741
A + S+ Y+A SPDE ALV + LV R + ++ P L+F +L
Sbjct: 573 ADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFP 632
Query: 742 FDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLN 801
F S KRM V++R T EI Y KGAD + ++Q + + + N
Sbjct: 633 FTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQ----------YNDWLEEECGNM-- 680
Query: 802 VYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGAT 861
A EGLRTL +AK+ L++E+Y + + +A+ S+ + + LE + LL T
Sbjct: 681 --AREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLT 738
Query: 862 GIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQE 921
G+ED+LQ V T+ LR AG++IW+LTGDK ETA IA + L+ +++ +
Sbjct: 739 GVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSR 798
Query: 922 ACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAY 981
A +++ +R + C +LVI G SL
Sbjct: 799 GEA--------HLELNAFRRKHD-------------C------------ALVISGDSLEV 825
Query: 982 ALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQV 1041
L K E +F+ LA QC +V+CCR +P QK+ +V L++ T AIGDG NDVSMIQ
Sbjct: 826 CL-KYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQA 884
Query: 1042 ADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVG 1101
AD G+GI G+EG QA +A+DF++ +FR++ RLL++HG Y R A + + ++ +
Sbjct: 885 ADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIIST 944
Query: 1102 LLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQ 1161
+ F F AS + Q +L+ ++ P+ + VLD+DV + + P+LYK
Sbjct: 945 MQAVFSSVFYF-ASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLT 1003
Query: 1162 NMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGI 1221
+TF + + +Q + + + V + T +LT LL + +
Sbjct: 1004 KGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVHVVAIS---FTALILTELLMVAL 1060
Query: 1222 ETKTWTWL 1229
+TW WL
Sbjct: 1061 TVRTWHWL 1068
Score = 162 bits (409), Expect = 3e-39
Identities = 115/401 (28%), Positives = 195/401 (48%), Gaps = 36/401 (8%)
Query: 55 CAQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAP 114
C + N +K KY + +F+P L+EQF N+YF+ I+ FVPA+ AP
Sbjct: 126 CEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAP 185
Query: 115 VLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCN 174
+ F+LA+T R+ +++ R + D ++N + K V +I VGD + + N
Sbjct: 186 LGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKS--SDIQVGDLIIVEKN 243
Query: 175 EIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECE 234
+ P+D++ L +S+ G C I T LDGET+ K + V +L + + + ++ + +
Sbjct: 244 QRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQ 303
Query: 235 KPNNDLSRFRGCIIHDNGK---KAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLN 291
KP D+ F G ++ L EN L T+ + V+G+VIY G ET++++N
Sbjct: 304 KPQMDIHSFEGTFTREDSDPPIHESLSIENTLW-ASTIVASGTVIGVVIYTGKETRSVMN 362
Query: 292 NSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSS 351
S P+ K L+ ++N L LV +S+ G
Sbjct: 363 TSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF--------------------- 401
Query: 352 LSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRA 411
+ P ++ FL ++ +IPISL V++++ KA + M + DE + R
Sbjct: 402 VGPWYRNLFRFL---LLFSYIIPISLRVNLDMGKAVYGW-----MMMKDENIPGTV-VRT 452
Query: 412 LNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHD 452
I E+LG++ Y+ +DKTGTLT+N+M+F+R + V Y D
Sbjct: 453 STIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGAD 493
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 78.2 bits (191), Expect = 6e-14
Identities = 56/179 (31%), Positives = 89/179 (49%), Gaps = 29/179 (16%)
Query: 742 FDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQN--- 798
F+SVRK MS VIR+P +Y+KGA ++ L+ C+ + R ++K ++
Sbjct: 568 FNSVRKSMSTVIRNP-NGGFRMYSKGASEII---LRKCNRILDRKGEAVPFKNKDRDDMV 623
Query: 799 --YLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLH 856
+ A +GLRT+CIA R + E S +N E+L T L
Sbjct: 624 RTVIEPMACDGLRTICIAYRDFD------------DTEPSWDNENEIL--------TELT 663
Query: 857 LLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITL 915
+ GIED ++ VP+ I+K +QAG+ + ++TGD TA IA C +L ++ + L
Sbjct: 664 CIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCL 722
Score = 45.1 bits (105), Expect = 5e-04
Identities = 78/368 (21%), Positives = 146/368 (39%), Gaps = 66/368 (17%)
Query: 112 LAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWK-------EIH 164
L V+ ++ +TAF D W + R L C + +E+K + R + EI
Sbjct: 156 LFSVIIVVLVTAFND-WSKEKQFRG------LQCRI-EQEQKFSIIRNGQLIQLPVAEIV 207
Query: 165 VGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSEL----VS 220
VGD +++ ++ PAD +L+ +D I+ ++L GE++ ++ + + L V
Sbjct: 208 VGDIAQVKYGDLLPADGILIQGND----LKIDESSLTGESDHVKKSLDKDPMLLSGTHVM 263
Query: 221 EFNPLTFTSVIECEKPNNDLSRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVI 280
E + + + + G D G+K K+ + T V + I
Sbjct: 264 EGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEI 323
Query: 281 YAGHETKALLNNSG-------PRYKRSKLERQMN---CDVLWCVLLLVCMSLFSAVGHGL 330
+ + + N P+ ++S L+ ++ + LL+ +++F +
Sbjct: 324 QPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILI---- 379
Query: 331 WIWRYQEKKSLFYVPKSDGSSLSP---------VTAAVYSFLTMIIVLQVLIPISLYVSI 381
L++V + + P + V F+ I VL V +P L +++
Sbjct: 380 ----------LYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAV 429
Query: 382 EIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRR 441
I A V + +D L R L+ E +G I SDKTGTLT N+M +
Sbjct: 430 TISLAYSVKKMMKDNNLV----------RHLDACETMGNATAICSDKTGTLTMNRMTVVQ 479
Query: 442 CTVSGVEY 449
+ G+ Y
Sbjct: 480 AYIGGIHY 487
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 78.2 bits (191), Expect = 6e-14
Identities = 56/179 (31%), Positives = 89/179 (49%), Gaps = 29/179 (16%)
Query: 742 FDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQN--- 798
F+SVRK MS VIR+P +Y+KGA ++ L+ C+ + R ++K ++
Sbjct: 568 FNSVRKSMSTVIRNP-NGGFRMYSKGASEII---LRKCNRILDRKGEAVPFKNKDRDDMV 623
Query: 799 --YLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLH 856
+ A +GLRT+CIA R + E S +N E+L T L
Sbjct: 624 RTVIEPMACDGLRTICIAYRDFD------------DTEPSWDNENEIL--------TELT 663
Query: 857 LLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITL 915
+ GIED ++ VP+ I+K +QAG+ + ++TGD TA IA C +L ++ + L
Sbjct: 664 CIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCL 722
Score = 45.1 bits (105), Expect = 5e-04
Identities = 78/368 (21%), Positives = 146/368 (39%), Gaps = 66/368 (17%)
Query: 112 LAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWK-------EIH 164
L V+ ++ +TAF D W + R L C + +E+K + R + EI
Sbjct: 156 LFSVIIVVLVTAFND-WSKEKQFRG------LQCRI-EQEQKFSIIRNGQLIQLPVAEIV 207
Query: 165 VGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSEL----VS 220
VGD +++ ++ PAD +L+ +D I+ ++L GE++ ++ + + L V
Sbjct: 208 VGDIAQVKYGDLLPADGILIQGND----LKIDESSLTGESDHVKKSLDKDPMLLSGTHVM 263
Query: 221 EFNPLTFTSVIECEKPNNDLSRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVI 280
E + + + + G D G+K K+ + T V + I
Sbjct: 264 EGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEI 323
Query: 281 YAGHETKALLNNSG-------PRYKRSKLERQMN---CDVLWCVLLLVCMSLFSAVGHGL 330
+ + + N P+ ++S L+ ++ + LL+ +++F +
Sbjct: 324 QPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILI---- 379
Query: 331 WIWRYQEKKSLFYVPKSDGSSLSP---------VTAAVYSFLTMIIVLQVLIPISLYVSI 381
L++V + + P + V F+ I VL V +P L +++
Sbjct: 380 ----------LYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAV 429
Query: 382 EIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRR 441
I A V + +D L R L+ E +G I SDKTGTLT N+M +
Sbjct: 430 TISLAYSVKKMMKDNNLV----------RHLDACETMGNATAICSDKTGTLTMNRMTVVQ 479
Query: 442 CTVSGVEY 449
+ G+ Y
Sbjct: 480 AYIGGIHY 487
>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
Length = 1175
Score = 74.3 bits (181), Expect = 8e-13
Identities = 105/432 (24%), Positives = 170/432 (39%), Gaps = 64/432 (14%)
Query: 736 LLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSK 795
+LH F S +RMSVV+ P + Y KG+ +V L P + + +
Sbjct: 619 VLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCNP-----------ETVPTD 667
Query: 796 TQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNL 855
L Y A G R + +A + L SLE +++L + +E +L
Sbjct: 668 FAQMLQSYTAAGYRVVALASKPLP-------------TVPSLEAAQQLTRDT---VEGDL 711
Query: 856 HLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITL 915
LLG + + L+ I LR+ ++ ++TGD +TAV +A C ++ E +I +
Sbjct: 712 SLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771
Query: 916 NATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVS-MRFSSLCPPSTSTASGRRPSLVI 974
+AT E Q L+ P ++ V+ ++ T R L +
Sbjct: 772 HATHPER-----------GQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLAL 820
Query: 975 DGRSLAYALE--KNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDG 1032
G + ++ L K L + + R P QK+ +V ++ KL+ GDG
Sbjct: 821 SGPTFGIIVKHFPKLLPKVL-----VQGTVFARMAPEQKTELVCELQ-KLQYCVGMCGDG 874
Query: 1033 ANDVSMIQVADVGVGISGQEG-----MQAVMASDFAVPKFRYLERLLILHGHWCYSRLAN 1087
AND ++ ADVG+ +S E + MAS VP ++I G +
Sbjct: 875 ANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVP-------MVIREGRCSLDTSFS 927
Query: 1088 MVLYF-FYKNTMFVG--LLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRD 1144
+ Y Y T F+ +L+ G ID +L S P + VL R
Sbjct: 928 VFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPAL--VLGRV 985
Query: 1145 VPANVLLTNPQL 1156
P LL+ P L
Sbjct: 986 RPPGALLSVPVL 997
>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
Length = 1180
Score = 74.3 bits (181), Expect = 8e-13
Identities = 105/432 (24%), Positives = 170/432 (39%), Gaps = 64/432 (14%)
Query: 736 LLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSK 795
+LH F S +RMSVV+ P + Y KG+ +V L P + + +
Sbjct: 624 VLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCNP-----------ETVPTD 672
Query: 796 TQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNL 855
L Y A G R + +A + L SLE +++L + +E +L
Sbjct: 673 FAQMLQSYTAAGYRVVALASKPLP-------------TVPSLEAAQQLTRDT---VEGDL 716
Query: 856 HLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITL 915
LLG + + L+ I LR+ ++ ++TGD +TAV +A C ++ E +I +
Sbjct: 717 SLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 776
Query: 916 NATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVS-MRFSSLCPPSTSTASGRRPSLVI 974
+AT E Q L+ P ++ V+ ++ T R L +
Sbjct: 777 HATHPER-----------GQPASLEFLPMESPTAVNGVKDPDQAASYTVEPDPRSRHLAL 825
Query: 975 DGRSLAYALE--KNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDG 1032
G + ++ L K L + + R P QK+ +V ++ KL+ GDG
Sbjct: 826 SGPTFGIIVKHFPKLLPKVL-----VQGTVFARMAPEQKTELVCELQ-KLQYCVGMCGDG 879
Query: 1033 ANDVSMIQVADVGVGISGQEG-----MQAVMASDFAVPKFRYLERLLILHGHWCYSRLAN 1087
AND ++ ADVG+ +S E + MAS VP ++I G +
Sbjct: 880 ANDCGALKAADVGISLSQAEASVVSPFTSSMASIECVP-------MVIREGRCSLDTSFS 932
Query: 1088 MVLYF-FYKNTMFVG--LLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRD 1144
+ Y Y T F+ +L+ G ID +L S P + VL R
Sbjct: 933 VFKYMALYSLTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPAL--VLGRV 990
Query: 1145 VPANVLLTNPQL 1156
P LL+ P L
Sbjct: 991 RPPGALLSVPVL 1002
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 73.6 bits (179), Expect = 1e-12
Identities = 54/179 (30%), Positives = 87/179 (48%), Gaps = 28/179 (15%)
Query: 742 FDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSV-----DARGRHQKKIRSKT 796
F+SVRK MS VIR P +++KGA + LL+ C+++ + RG +
Sbjct: 576 FNSVRKSMSTVIRMP-DGGFRLFSKGASEI---LLKKCTNILNSNGELRGFRPRDRDDMV 631
Query: 797 QNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLH 856
+ + A +GLRT+CIA R S + W +N E++ +L
Sbjct: 632 RKIIEPMACDGLRTICIAYRDFSAGQEPDW-----------DNENEVV--------GDLT 672
Query: 857 LLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITL 915
+ GIED ++ VPE I K ++AG+ + ++TGD TA IA C ++ E+ + L
Sbjct: 673 CIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCL 731
Score = 36.6 bits (83), Expect = 0.19
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 362 FLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQI 421
F+ + VL V +P L +++ I A V + +D L R L+ E +G
Sbjct: 418 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 467
Query: 422 QYIFSDKTGTLTENKMVFRRCTVSGVEY 449
I SDKTGTLT N+M + + Y
Sbjct: 468 TAICSDKTGTLTTNRMTVVQSYLGDTHY 495
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 73.6 bits (179), Expect = 1e-12
Identities = 54/179 (30%), Positives = 87/179 (48%), Gaps = 28/179 (15%)
Query: 742 FDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSV-----DARGRHQKKIRSKT 796
F+SVRK MS VIR P +++KGA + LL+ C+++ + RG +
Sbjct: 576 FNSVRKSMSTVIRMP-DGGFRLFSKGASEI---LLKKCTNILNSNGELRGFRPRDRDDMV 631
Query: 797 QNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLH 856
+ + A +GLRT+CIA R S + W +N E++ +L
Sbjct: 632 RKIIEPMACDGLRTICIAYRDFSAGQEPDW-----------DNENEVV--------GDLT 672
Query: 857 LLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITL 915
+ GIED ++ VPE I K ++AG+ + ++TGD TA IA C ++ E+ + L
Sbjct: 673 CIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCL 731
Score = 36.6 bits (83), Expect = 0.19
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 362 FLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQI 421
F+ + VL V +P L +++ I A V + +D L R L+ E +G
Sbjct: 418 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 467
Query: 422 QYIFSDKTGTLTENKMVFRRCTVSGVEY 449
I SDKTGTLT N+M + + Y
Sbjct: 468 TAICSDKTGTLTTNRMTVVQSYLGDTHY 495
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 70.1 bits (170), Expect = 2e-11
Identities = 104/456 (22%), Positives = 177/456 (38%), Gaps = 105/456 (23%)
Query: 742 FDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQN--- 798
F+SVRK MS V+++ +++KGA ++ L+ C + + K R + ++
Sbjct: 578 FNSVRKSMSTVLKNS-DGSYRIFSKGASEII---LKKCFKILSANGEAKVFRPRDRDDIV 633
Query: 799 --YLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLH 856
+ A+EGLRT+C+A R E E +N +++ T L
Sbjct: 634 KTVIEPMASEGLRTICLAFRDFPAGE----------PEPEWDNENDIV--------TGLT 675
Query: 857 LLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLN 916
+ GIED ++ VP+ I K ++AG+ + ++TGD TA IA C +L E+ + L
Sbjct: 676 CIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL- 734
Query: 917 ATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSM-RFSSLCPPSTSTASGRRPSLVID 975
+ + R KG++ R + P
Sbjct: 735 ------------------EGKDFNRRIRNEKGEIEQERIDKIWP---------------- 760
Query: 976 GRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLV----RSKLKAMTLAIGD 1031
K LA RS+P K +VK + S + + GD
Sbjct: 761 --------------KLRVLA---------RSSPTDKHTLVKGIIDSTVSDQRQVVAVTGD 797
Query: 1032 GANDVSMIQVADVG--VGISGQEGMQAVMASDFAVPKFRYLERL-LILHGHWCYSRLANM 1088
G ND ++ ADVG +GI+G + A ASD + + + ++ G Y ++
Sbjct: 798 GTNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKF 855
Query: 1089 VLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPAN 1148
+ + N V ++ F C + + + +++ NL+ +L L L + P
Sbjct: 856 LQFQLTVNV--VAVIVAFTGAC-ITQDSPLKAVQMLWVNLIMDTLASL---ALATEPPTE 909
Query: 1149 VLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLV 1184
LL L K + RT N+ AF LV
Sbjct: 910 SLL----LRKPYGRNKPLISRTMMKNILGHAFYQLV 941
Score = 36.6 bits (83), Expect = 0.19
Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 362 FLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQI 421
F+ + VL V +P L +++ I A V + +D L R L+ E +G
Sbjct: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 469
Query: 422 QYIFSDKTGTLTENKMVFRRCTVSGVEY 449
I SDKTGTLT N+M + ++ Y
Sbjct: 470 TAICSDKTGTLTMNRMTVVQAYINEKHY 497
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 70.1 bits (170), Expect = 2e-11
Identities = 104/456 (22%), Positives = 177/456 (38%), Gaps = 105/456 (23%)
Query: 742 FDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQN--- 798
F+SVRK MS V+++ +++KGA ++ L+ C + + K R + ++
Sbjct: 578 FNSVRKSMSTVLKNS-DGSYRIFSKGASEII---LKKCFKILSANGEAKVFRPRDRDDIV 633
Query: 799 --YLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLH 856
+ A+EGLRT+C+A R E E +N +++ T L
Sbjct: 634 KTVIEPMASEGLRTICLAFRDFPAGE----------PEPEWDNENDIV--------TGLT 675
Query: 857 LLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLN 916
+ GIED ++ VP+ I K ++AG+ + ++TGD TA IA C +L E+ + L
Sbjct: 676 CIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL- 734
Query: 917 ATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSM-RFSSLCPPSTSTASGRRPSLVID 975
+ + R KG++ R + P
Sbjct: 735 ------------------EGKDFNRRIRNEKGEIEQERIDKIWP---------------- 760
Query: 976 GRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLV----RSKLKAMTLAIGD 1031
K LA RS+P K +VK + S + + GD
Sbjct: 761 --------------KLRVLA---------RSSPTDKHTLVKGIIDSTVSDQRQVVAVTGD 797
Query: 1032 GANDVSMIQVADVG--VGISGQEGMQAVMASDFAVPKFRYLERL-LILHGHWCYSRLANM 1088
G ND ++ ADVG +GI+G + A ASD + + + ++ G Y ++
Sbjct: 798 GTNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKF 855
Query: 1089 VLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPAN 1148
+ + N V ++ F C + + + +++ NL+ +L L L + P
Sbjct: 856 LQFQLTVNV--VAVIVAFTGAC-ITQDSPLKAVQMLWVNLIMDTLASL---ALATEPPTE 909
Query: 1149 VLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLV 1184
LL L K + RT N+ AF LV
Sbjct: 910 SLL----LRKPYGRNKPLISRTMMKNILGHAFYQLV 941
Score = 36.6 bits (83), Expect = 0.19
Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 362 FLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQI 421
F+ + VL V +P L +++ I A V + +D L R L+ E +G
Sbjct: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 469
Query: 422 QYIFSDKTGTLTENKMVFRRCTVSGVEY 449
I SDKTGTLT N+M + ++ Y
Sbjct: 470 TAICSDKTGTLTMNRMTVVQAYINEKHY 497
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens]
Length = 1198
Score = 68.9 bits (167), Expect = 3e-11
Identities = 77/323 (23%), Positives = 126/323 (39%), Gaps = 93/323 (28%)
Query: 742 FDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQN--- 798
F+SVRK MS VI+ P + +Y+KGA +V L+ C + + R + ++
Sbjct: 557 FNSVRKSMSTVIKLP-DESFRMYSKGASEIV---LKKCCKILNGAGEPRVFRPRDRDEMV 612
Query: 799 --YLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLH 856
+ A +GLRT+C+A R W +N ++L L
Sbjct: 613 KKVIEPMACDGLRTICVAYRDFPSSPEPDW-----------DNENDIL--------NELT 653
Query: 857 LLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLN 916
+ GIED ++ VPE I K ++AG+ + ++TGD TA IA C ++ E+ + L
Sbjct: 654 CICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCL- 712
Query: 917 ATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSM-RFSSLCPPSTSTASGRRPSLVID 975
+ + R KG++ R + P
Sbjct: 713 ------------------EGKEFNRRIRNEKGEIEQERIDKIWP---------------- 738
Query: 976 GRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLV----RSKLKAMTLAIGD 1031
K LA RS+P K +VK + ++ + + GD
Sbjct: 739 --------------KLRVLA---------RSSPTDKHTLVKGIIDSTHTEQRQVVAVTGD 775
Query: 1032 GANDVSMIQVADVG--VGISGQE 1052
G ND ++ ADVG +GI+G +
Sbjct: 776 GTNDGPALKKADVGFAMGIAGTD 798
Score = 39.7 bits (91), Expect = 0.022
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 362 FLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQI 421
F+ + VL V +P L +++ I A V + +D L R L+ E +G
Sbjct: 399 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 448
Query: 422 QYIFSDKTGTLTENKMVFRRCTVSGVEY 449
I SDKTGTLT N+M + V V Y
Sbjct: 449 TAICSDKTGTLTTNRMTVVQAYVGDVHY 476
Score = 31.2 bits (69), Expect = 7.9
Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 19/107 (17%)
Query: 112 LAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWK-------EIH 164
L V+ ++ +TAF D W + R +E+K V R + EI
Sbjct: 158 LLSVICVVLVTAFND-WSKEKQFRGLQSR-------IEQEQKFTVVRAGQVVQIPVAEIV 209
Query: 165 VGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQV 211
VGD +++ ++ PAD L + +D I+ ++L GE++ R+ V
Sbjct: 210 VGDIAQVKYGDLLPADGLFIQGND----LKIDESSLTGESDQVRKSV 252
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens]
Length = 1243
Score = 68.9 bits (167), Expect = 3e-11
Identities = 77/323 (23%), Positives = 126/323 (39%), Gaps = 93/323 (28%)
Query: 742 FDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQN--- 798
F+SVRK MS VI+ P + +Y+KGA +V L+ C + + R + ++
Sbjct: 602 FNSVRKSMSTVIKLP-DESFRMYSKGASEIV---LKKCCKILNGAGEPRVFRPRDRDEMV 657
Query: 799 --YLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLH 856
+ A +GLRT+C+A R W +N ++L L
Sbjct: 658 KKVIEPMACDGLRTICVAYRDFPSSPEPDW-----------DNENDIL--------NELT 698
Query: 857 LLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLN 916
+ GIED ++ VPE I K ++AG+ + ++TGD TA IA C ++ E+ + L
Sbjct: 699 CICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCL- 757
Query: 917 ATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSM-RFSSLCPPSTSTASGRRPSLVID 975
+ + R KG++ R + P
Sbjct: 758 ------------------EGKEFNRRIRNEKGEIEQERIDKIWP---------------- 783
Query: 976 GRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLV----RSKLKAMTLAIGD 1031
K LA RS+P K +VK + ++ + + GD
Sbjct: 784 --------------KLRVLA---------RSSPTDKHTLVKGIIDSTHTEQRQVVAVTGD 820
Query: 1032 GANDVSMIQVADVG--VGISGQE 1052
G ND ++ ADVG +GI+G +
Sbjct: 821 GTNDGPALKKADVGFAMGIAGTD 843
Score = 39.7 bits (91), Expect = 0.022
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 362 FLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQI 421
F+ + VL V +P L +++ I A V + +D L R L+ E +G
Sbjct: 444 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 493
Query: 422 QYIFSDKTGTLTENKMVFRRCTVSGVEY 449
I SDKTGTLT N+M + V V Y
Sbjct: 494 TAICSDKTGTLTTNRMTVVQAYVGDVHY 521
Score = 31.2 bits (69), Expect = 7.9
Identities = 28/107 (26%), Positives = 49/107 (45%), Gaps = 19/107 (17%)
Query: 112 LAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWK-------EIH 164
L V+ ++ +TAF D W + R +E+K V R + EI
Sbjct: 158 LLSVICVVLVTAFND-WSKEKQFRGLQSR-------IEQEQKFTVVRAGQVVQIPVAEIV 209
Query: 165 VGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQV 211
VGD +++ ++ PAD L + +D I+ ++L GE++ R+ V
Sbjct: 210 VGDIAQVKYGDLLPADGLFIQGND----LKIDESSLTGESDQVRKSV 252
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 68.2 bits (165), Expect = 6e-11
Identities = 85/379 (22%), Positives = 150/379 (39%), Gaps = 59/379 (15%)
Query: 736 LLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSK 795
+LH F S +RM+V+++ D + + KGA V QP + + +
Sbjct: 595 ILHQFPFSSALQRMTVIVQEMGGDRL-AFMKGAPERVASFCQP-----------ETVPTS 642
Query: 796 TQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNL 855
+ L +Y +G R + +A + L + +A L +E++L
Sbjct: 643 FVSELQIYTTQGFRVIALAYKKLENDHHATTLTRET-------------------VESDL 683
Query: 856 HLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITL 915
LG +E+RL++ + +L A ++ ++TGD +TA+ +A ++ ++VI +
Sbjct: 684 IFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILI 743
Query: 916 NATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPS--LV 973
A ++ + + + + + S GR S
Sbjct: 744 EANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSD---------KGREGSYHFA 794
Query: 974 IDGRSLAYALE--KNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGD 1031
+ G+S + +L K L + R +P QKS +V+ + KL GD
Sbjct: 795 LTGKSFHVISQHFSSLLPKILI-----NGTIFARMSPGQKSSLVEEFQ-KLDYFVGMCGD 848
Query: 1032 GANDVSMIQVADVGVGISGQEGMQAVMASDFA--VPKFRYLERLLILHGHWCYSRLANMV 1089
GAND +++A VG+ +S QE A +AS F P + LI G M
Sbjct: 849 GANDCGALKMAHVGISLSEQE---ASVASPFTSKTPNIECVPH-LIKEGRAALVTSFCMF 904
Query: 1090 LYF-FYKNTMFVG--LLFW 1105
Y Y +VG LL+W
Sbjct: 905 KYMALYSMIQYVGVLLLYW 923
>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
Length = 1158
Score = 66.6 bits (161), Expect = 2e-10
Identities = 102/429 (23%), Positives = 159/429 (37%), Gaps = 97/429 (22%)
Query: 736 LLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSK 795
+LH F S +RMSVV+ P + Y KG+ +V L P + + +
Sbjct: 619 VLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLCNP-----------ETVPTD 667
Query: 796 TQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNL 855
L Y A G R + +A + L SLE +++L + +E +L
Sbjct: 668 FAQMLQSYTAAGYRVVALASKPLP-------------TVPSLEAAQQLTRDT---VEGDL 711
Query: 856 HLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITL 915
LLG + + L+ I LR+ ++ ++TGD +TAV +A C ++ E +I +
Sbjct: 712 SLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIV 771
Query: 916 NATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVID 975
+AT E RG + E P + TA LV
Sbjct: 772 HATHPE---------------RGQPASLE------------FLPMESPTAVNGVKVLV-- 802
Query: 976 GRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGAND 1035
+ + R P QK+ +V ++ KL+ GDGAND
Sbjct: 803 -----------------------QGTVFARMAPEQKTELVCELQ-KLQYCVGMCGDGAND 838
Query: 1036 VSMIQVADVGVGISGQEG-----MQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVL 1090
++ ADVG+ +S E + MAS VP ++I G ++
Sbjct: 839 CGALKAADVGISLSQAEASVVSPFTSSMASIECVP-------MVIREGRCSLDTSFSVFK 891
Query: 1091 YF-FYKNTMFVG--LLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPA 1147
Y Y T F+ +L+ G ID +L S P + VL R P
Sbjct: 892 YMALYSLTQFISVLILYTINTNLGDLQFLAIDLVITTTVAVLMSRTGPAL--VLGRVRPP 949
Query: 1148 NVLLTNPQL 1156
LL+ P L
Sbjct: 950 GALLSVPVL 958
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,425,950
Number of Sequences: 37866
Number of extensions: 2655807
Number of successful extensions: 9216
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 8821
Number of HSP's gapped (non-prelim): 281
length of query: 1499
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1384
effective length of database: 13,892,928
effective search space: 19227812352
effective search space used: 19227812352
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.