Guide to the Human Genome
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Search of human proteins with 109689711

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109689711 gasdermin-like isoform 2 [Homo sapiens]
         (394 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109689711 gasdermin-like isoform 2 [Homo sapiens]                  771   0.0  
gi|109689703 gasdermin-like isoform 1 [Homo sapiens]                  763   0.0  
gi|150456463 gasdermin 1 [Homo sapiens]                               131   1e-30
gi|83320070 gasdermin D [Homo sapiens]                                 85   1e-16
gi|13899221 melanoma-derived leucine zipper, extra-nuclear facto...    49   8e-06
gi|4758154 deafness, autosomal dominant 5 protein isoform a [Hom...    42   7e-04
gi|188536092 deafness, autosomal dominant 5 protein isoform a [H...    42   7e-04
gi|118498362 kinectin 1 isoform b [Homo sapiens]                       39   0.006
gi|111607457 deafness, autosomal recessive 59 [Homo sapiens]           38   0.014
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       38   0.018
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       38   0.018
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        38   0.018
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             38   0.018
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    35   0.090
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    35   0.090
gi|156071420 hypothetical protein LOC728912 [Homo sapiens]             34   0.20 
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho...    34   0.20 
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    34   0.20 
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom...    34   0.26 
gi|126362971 serine/threonine kinase 10 [Homo sapiens]                 33   0.34 
gi|45356151 non-SMC condensin II complex, subunit D3 [Homo sapiens]    33   0.34 
gi|24308219 synaptotagmin IV [Homo sapiens]                            33   0.34 
gi|63054866 leucine rich repeat containing 16A [Homo sapiens]          33   0.45 
gi|148746195 trichohyalin [Homo sapiens]                               33   0.45 
gi|224586823 coiled-coil domain containing 110 isoform b [Homo s...    33   0.58 
gi|22749515 coiled-coil domain containing 110 isoform a [Homo sa...    33   0.58 
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     33   0.58 
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa...    33   0.58 
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap...    33   0.58 
gi|110347568 centrosomal protein 152kDa [Homo sapiens]                 33   0.58 

>gi|109689711 gasdermin-like isoform 2 [Homo sapiens]
          Length = 394

 Score =  771 bits (1992), Expect = 0.0
 Identities = 394/394 (100%), Positives = 394/394 (100%)

Query: 1   MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60
           MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD
Sbjct: 1   MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60

Query: 61  ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120
           ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI
Sbjct: 61  ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120

Query: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180
           SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS
Sbjct: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180

Query: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDME 240
           QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDME
Sbjct: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDME 240

Query: 241 SVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNA 300
           SVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNA
Sbjct: 241 SVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNA 300

Query: 301 AGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSP 360
           AGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSP
Sbjct: 301 AGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSP 360

Query: 361 PDMDYDPEARILCALYVVVSILLELAEGPTSVSS 394
           PDMDYDPEARILCALYVVVSILLELAEGPTSVSS
Sbjct: 361 PDMDYDPEARILCALYVVVSILLELAEGPTSVSS 394


>gi|109689703 gasdermin-like isoform 1 [Homo sapiens]
          Length = 403

 Score =  763 bits (1969), Expect = 0.0
 Identities = 393/403 (97%), Positives = 394/403 (97%), Gaps = 9/403 (2%)

Query: 1   MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60
           MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD
Sbjct: 1   MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60

Query: 61  ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120
           ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI
Sbjct: 61  ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120

Query: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180
           SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS
Sbjct: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180

Query: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR---------KSLGSEDSRN 231
           QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETM+         KSLGSEDSRN
Sbjct: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRN 240

Query: 232 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK 291
           MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK
Sbjct: 241 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK 300

Query: 292 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ 351
           PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ
Sbjct: 301 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ 360

Query: 352 NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS 394
           NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS
Sbjct: 361 NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS 403


>gi|150456463 gasdermin 1 [Homo sapiens]
          Length = 445

 Score =  131 bits (329), Expect = 1e-30
 Identities = 129/462 (27%), Positives = 214/462 (46%), Gaps = 97/462 (20%)

Query: 3   SVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRT---FFGCRHYTTGLTLM 59
           ++FE +TR + ++++  GD+  + SL+D  RF  F LV  KR    F+G R+  T  TL+
Sbjct: 2   TMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTLL 61

Query: 60  DILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIK 119
           D+L+  G    D  D+G  G K      + +D+  E  V +PK + + G+     +  ++
Sbjct: 62  DVLEP-GSSPSDPTDTGNFGFK------NMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLE 114

Query: 120 ISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYK-- 177
           +    ++ + L T++ RKL  + PF     +  ENLY+V E +ETV+E TL+   + +  
Sbjct: 115 VQTLSVAPKALETVQERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEAC 174

Query: 178 ----FWSQIS-QGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKE-------------- 218
               F++ +  QG +++K      VTIP   VL++RV+QL+   K+              
Sbjct: 175 FSLPFFAPLGLQGSINHK----EAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQT 230

Query: 219 --------------TMRKSLGS--EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCL 262
                              +G   E  R +KE+++     ++ L+   +  +L+SL+K L
Sbjct: 231 FPPGEKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLL 290

Query: 263 GKEDIRQDLEQRVSEVLISG-ELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLE 321
           GK+   QDLE  +   L  G E+ +E   K +L         L +    AIL F+ AL E
Sbjct: 291 GKKKELQDLELALEGALDKGHEVTLEALPKDVL---------LSKEAVGAILYFVGALTE 341

Query: 322 LSEEQQ-FVAEALEKGTLPLLKDQVKSVMEQNW--------------------------- 353
           LSE QQ  + +++EK  LP+    V+S MEQN+                           
Sbjct: 342 LSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTE 401

Query: 354 -------DELASSPPDMDYDPEA-RILCALYVVVSILLELAE 387
                   E+  S P   +DP+    LCALY  +S+L +L +
Sbjct: 402 ALVGLSGLEVQRSGPQYMWDPDTLPRLCALYAGLSLLQQLTK 443


>gi|83320070 gasdermin D [Homo sapiens]
          Length = 484

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 120/494 (24%), Positives = 206/494 (41%), Gaps = 116/494 (23%)

Query: 1   MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRT---FFGCRHYTTGLT 57
           M S FE + R VV+E+D GG+ I V SL  +  F+ + LV  K +   F+  R+    L+
Sbjct: 1   MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLS 60

Query: 58  LMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDS--TGELIVRLPKEITISGSFQGFHH 115
           + DIL+ D  +   ++  G       F   D +D    G + +  P +  I+G       
Sbjct: 61  IKDILEPDAAE--PDVQRG-----RSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDS 113

Query: 116 QKIKISENRIS---QQYLATLENRKLKRELPFSFRSINTR-ENLYLVTETLETVKEETLK 171
               ++   +S     +   L  R L++      + + +R +N+Y+VTE L+T KE  + 
Sbjct: 114 SSTSMNVYSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVT 173

Query: 172 SDRQYKFWSQIS-----------QGHLSYKHKGQREVTIPPNRVLSYRVKQLV------- 213
              + +   + S           QGHLS K    + VTIP    L++RV QLV       
Sbjct: 174 RTHKREGSGRFSLPGATCLQGEGQGHLSQK----KTVTIPSGSTLAFRVAQLVIDSDLDV 229

Query: 214 --FPNKE---------------------------TMRKSLG-------------SEDSRN 231
             FP+K+                           +M + L              +ED + 
Sbjct: 230 LLFPDKKQRTFQPPATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQG 289

Query: 232 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELH-MEDPD 290
           ++ ++E +   L+ L  E  + +L  L   L  +   + LE+ + +    G +  ++ P 
Sbjct: 290 LRAEVETISKELELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPA 349

Query: 291 KPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQ-QFVAEALEKGTLPLLKDQVKSVM 349
             +L  L  ++G+LV   A  ++  L AL  LSE Q + +AEALE  TL    + V S++
Sbjct: 350 GAVLECLVLSSGMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLL 409

Query: 350 EQN--WD-------------------------------ELASSPPDMDYDPEAR-ILCAL 375
           EQ+  W                                EL    P + ++P+A+  +CAL
Sbjct: 410 EQSAPWQERSTMSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQAQGRMCAL 469

Query: 376 YVVVSILLELAEGP 389
           Y  +++L  L++ P
Sbjct: 470 YASLALLSGLSQEP 483


>gi|13899221 melanoma-derived leucine zipper, extra-nuclear factor
           [Homo sapiens]
          Length = 508

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 60/256 (23%), Positives = 110/256 (42%), Gaps = 22/256 (8%)

Query: 1   MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKR----TFFGCRHYT-TG 55
           M S+ E I++ +VKE+ +  D+  V+ L+ A + R F ++ +K+    +F+    Y    
Sbjct: 1   MPSMLERISKNLVKEIGSK-DLTPVKYLLSATKLRQFVILRKKKDSRSSFWEQSDYVPVE 59

Query: 56  LTLMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHH 115
            +L DIL+         L++ + G    F  +       ++ V +  E+++SG     H 
Sbjct: 60  FSLNDILEPSSSV----LETVVTGP-FHFSDIMIQKHKADMGVNVGIEVSVSGEASVDHG 114

Query: 116 QKIKISENRISQQYLATLENRKLKRELPFSFRSINTR-ENLYLVTETLETVKEETLKSDR 174
             ++     I    L   + RKL    P   +    R +NLY+VTE +E +    L    
Sbjct: 115 CSLEFQIVTIPSPNLEDFQKRKLLDPEPSFLKECRRRGDNLYVVTEAVELINNTVLYDSS 174

Query: 175 QYKFWSQISQGHLSYKHKGQRE--------VTIPPNRVLSYRVKQLVFPNKETMRKSLGS 226
                 +I+      K +GQ E        +T+    V++Y+ KQLV   K  +      
Sbjct: 175 SVNILGKIALWITYGKGQGQGESLRVKKKALTLQKGMVMAYKRKQLVIKEKAILISD--D 232

Query: 227 EDSRNMKEKLEDMESV 242
           ++ R  +++ E  E V
Sbjct: 233 DEQRTFQDEYEISEMV 248


>gi|4758154 deafness, autosomal dominant 5 protein isoform a [Homo
          sapiens]
          Length = 496

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 5/66 (7%)

Query: 4  VFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGC----RHYTTGLTLM 59
          +F + TR  ++E+DA GD+IAV +L D+D+ +   LV +K+ F+ C    ++    LTL 
Sbjct: 1  MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFW-CWQRPKYQFLSLTLG 59

Query: 60 DILDTD 65
          D+L  D
Sbjct: 60 DVLIED 65


>gi|188536092 deafness, autosomal dominant 5 protein isoform a
          [Homo sapiens]
          Length = 496

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 5/66 (7%)

Query: 4  VFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGC----RHYTTGLTLM 59
          +F + TR  ++E+DA GD+IAV +L D+D+ +   LV +K+ F+ C    ++    LTL 
Sbjct: 1  MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFW-CWQRPKYQFLSLTLG 59

Query: 60 DILDTD 65
          D+L  D
Sbjct: 60 DVLIED 65


>gi|118498362 kinectin 1 isoform b [Homo sapiens]
          Length = 1306

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 37/154 (24%), Positives = 83/154 (53%), Gaps = 17/154 (11%)

Query: 216 NKE-TMRKSLGS--EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLE 272
           NKE T++ S+ S  ++ +N+ +  E+  + +K + EEK KD+ N+  K L  +D++++ E
Sbjct: 826 NKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENE 882

Query: 273 QRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQ 327
              + V    + ++++      +S F    ++++ +    L  L+A+L     +LS + Q
Sbjct: 883 SLKAHVQEVAQHNLKEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQ 938

Query: 328 FVAEALEKGTLPLLKDQVKSVMEQNWDELASSPP 361
            + +  ++    L K Q++ + +QN+ + +S PP
Sbjct: 939 LLQDVQDEN--KLFKSQIEQLKQQNYQQASSFPP 970



 Score = 28.9 bits (63), Expect = 8.4
 Identities = 32/139 (23%), Positives = 62/139 (44%), Gaps = 12/139 (8%)

Query: 162 LETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR 221
           L  VKE+   +  + K   Q++Q  ++ K +    +T   +R+ +   +  VF NK  + 
Sbjct: 341 LAAVKEDAAATKDRCK---QLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVS 397

Query: 222 KSLGSEDSRNMKEKLEDMESVLKDLTEEK---RKDVLNSLAKCLGKED-----IRQDLEQ 273
                +     ++  E ME+ +  L +E    R  V N+  +   K+      +RQD  +
Sbjct: 398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYAR 457

Query: 274 RVSEVL-ISGELHMEDPDK 291
            V+E+   +G+L  E+  K
Sbjct: 458 LVNELTEKTGKLQQEEVQK 476


>gi|111607457 deafness, autosomal recessive 59 [Homo sapiens]
          Length = 352

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 38/147 (25%), Positives = 64/147 (43%), Gaps = 23/147 (15%)

Query: 4   VFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHY---TTGLTLMD 60
           +F   T+  VK++  GG ++ V SL +AD+++   LV +K+  F    Y   +T  TL D
Sbjct: 1   MFAAATKSFVKQVGDGGRLVPVPSLSEADKYQPLSLVVKKKRCFLFPRYKFTSTPFTLKD 60

Query: 61  ILDTDGD-----------KWLDELDSGLQGQKAEFQILD---NVDSTGELIVR------L 100
           IL  D +            + DE D  L G++    + D   NV  +  + V+       
Sbjct: 61  ILLGDREISAGISSYQLLNYEDESDVSLYGRRGNHIVNDVGINVAGSDSIAVKASFGIVT 120

Query: 101 PKEITISGSFQGFHHQKIKISENRISQ 127
             E+ +S   +    +KI    + I Q
Sbjct: 121 KHEVEVSTLLKEITTRKINFDHSLIRQ 147


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 37.7 bits (86), Expect = 0.018
 Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 14/140 (10%)

Query: 227 EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHM 286
           ++ +N+ +  E+  + +K + EEK KD+ N+  K L  +D++++ E   + V    + ++
Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENESLKAHVQEVAQHNL 919

Query: 287 EDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQFVAEALEKGTLPLL 341
           ++      +S F    ++++ +    L  L+A+L     +LS + Q + +  ++    L 
Sbjct: 920 KEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQLLQDVQDEN--KLF 973

Query: 342 KDQVKSVMEQNWDELASSPP 361
           K Q++ + +QN+ + +S PP
Sbjct: 974 KSQIEQLKQQNYQQASSFPP 993



 Score = 28.9 bits (63), Expect = 8.4
 Identities = 32/139 (23%), Positives = 62/139 (44%), Gaps = 12/139 (8%)

Query: 162 LETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR 221
           L  VKE+   +  + K   Q++Q  ++ K +    +T   +R+ +   +  VF NK  + 
Sbjct: 341 LAAVKEDAAATKDRCK---QLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVS 397

Query: 222 KSLGSEDSRNMKEKLEDMESVLKDLTEEK---RKDVLNSLAKCLGKED-----IRQDLEQ 273
                +     ++  E ME+ +  L +E    R  V N+  +   K+      +RQD  +
Sbjct: 398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYAR 457

Query: 274 RVSEVL-ISGELHMEDPDK 291
            V+E+   +G+L  E+  K
Sbjct: 458 LVNELTEKTGKLQQEEVQK 476


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 37.7 bits (86), Expect = 0.018
 Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 14/140 (10%)

Query: 227 EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHM 286
           ++ +N+ +  E+  + +K + EEK KD+ N+  K L  +D++++ E   + V    + ++
Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENESLKAHVQEVAQHNL 919

Query: 287 EDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQFVAEALEKGTLPLL 341
           ++      +S F    ++++ +    L  L+A+L     +LS + Q + +  ++    L 
Sbjct: 920 KEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQLLQDVQDEN--KLF 973

Query: 342 KDQVKSVMEQNWDELASSPP 361
           K Q++ + +QN+ + +S PP
Sbjct: 974 KSQIEQLKQQNYQQASSFPP 993



 Score = 28.9 bits (63), Expect = 8.4
 Identities = 32/139 (23%), Positives = 62/139 (44%), Gaps = 12/139 (8%)

Query: 162 LETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR 221
           L  VKE+   +  + K   Q++Q  ++ K +    +T   +R+ +   +  VF NK  + 
Sbjct: 341 LAAVKEDAAATKDRCK---QLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVS 397

Query: 222 KSLGSEDSRNMKEKLEDMESVLKDLTEEK---RKDVLNSLAKCLGKED-----IRQDLEQ 273
                +     ++  E ME+ +  L +E    R  V N+  +   K+      +RQD  +
Sbjct: 398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYAR 457

Query: 274 RVSEVL-ISGELHMEDPDK 291
            V+E+   +G+L  E+  K
Sbjct: 458 LVNELTEKTGKLQQEEVQK 476


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 37.7 bits (86), Expect = 0.018
 Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 14/140 (10%)

Query: 227 EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHM 286
           ++ +N+ +  E+  + +K + EEK KD+ N+  K L  +D++++ E   + V    + ++
Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENESLKAHVQEVAQHNL 919

Query: 287 EDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQFVAEALEKGTLPLL 341
           ++      +S F    ++++ +    L  L+A+L     +LS + Q + +  ++    L 
Sbjct: 920 KEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQLLQDVQDEN--KLF 973

Query: 342 KDQVKSVMEQNWDELASSPP 361
           K Q++ + +QN+ + +S PP
Sbjct: 974 KSQIEQLKQQNYQQASSFPP 993



 Score = 28.9 bits (63), Expect = 8.4
 Identities = 32/139 (23%), Positives = 62/139 (44%), Gaps = 12/139 (8%)

Query: 162 LETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR 221
           L  VKE+   +  + K   Q++Q  ++ K +    +T   +R+ +   +  VF NK  + 
Sbjct: 341 LAAVKEDAAATKDRCK---QLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVS 397

Query: 222 KSLGSEDSRNMKEKLEDMESVLKDLTEEK---RKDVLNSLAKCLGKED-----IRQDLEQ 273
                +     ++  E ME+ +  L +E    R  V N+  +   K+      +RQD  +
Sbjct: 398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYAR 457

Query: 274 RVSEVL-ISGELHMEDPDK 291
            V+E+   +G+L  E+  K
Sbjct: 458 LVNELTEKTGKLQQEEVQK 476


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 37.7 bits (86), Expect = 0.018
 Identities = 65/285 (22%), Positives = 135/285 (47%), Gaps = 38/285 (13%)

Query: 78   QGQKAEFQILDNVDSTGELIVRLPKEI-TISGSFQGFHHQKIKISENRISQQYLATLENR 136
            Q +K E Q+  N++   +   +  K+I  + G  +    QK ++ EN++ QQ     +  
Sbjct: 949  QNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTEL-ENKLQQQLTQAAQEL 1007

Query: 137  KLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQRE 196
              ++E       I+  +N Y   ++ ET K+  L+SD  Y   S++       K   + +
Sbjct: 1008 AAEKE------KISVLQNNY--EKSQETFKQ--LQSDF-YGRESELLATRQDLKSV-EEK 1055

Query: 197  VTIPPNRVLSYRVKQLVFPNK-----ETMRKSLGSEDSRNMKEKLEDMESVLKDLTEE-- 249
            +++    ++S R  Q+   NK     +T + +L  +DS   +++L++    L+D+ +E  
Sbjct: 1056 LSLAQEDLISNR-NQIGNQNKLIQELKTAKATL-EQDSAKKEQQLQERCKALQDIQKEKS 1113

Query: 250  -KRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEAR 308
             K K+++N  +K    E+I+   E+ ++++    + H  +  K  +++L +A  +L++ +
Sbjct: 1114 LKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKE-ITNLKDAKQLLIQQK 1172

Query: 309  AKAILDFLDALLELSEEQQFVAEAL--EKGTLPLLKDQVKSVMEQ 351
                       LEL  +   +  A+  EK    +LKDQVK   E+
Sbjct: 1173 -----------LELQGKADSLKAAVEQEKRNQQILKDQVKKEEEE 1206


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 35.4 bits (80), Expect = 0.090
 Identities = 68/307 (22%), Positives = 125/307 (40%), Gaps = 41/307 (13%)

Query: 70   LDELDSGLQGQKAEFQI-LDNVDSTGELIVR----LPKEITISGSFQGFHHQKIKISENR 124
            L  +   L+ +K+EF++ LD+V S  E I++    L K           H  K + ++  
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269

Query: 125  I----SQQYLATLENRKLKRELPFSFRSIN--TRENLYLVTETLETVK---EETLKSDRQ 175
            +    SQ+     EN +L R+L      I+  TR  L   T+ LE +K   EE +K+   
Sbjct: 1270 VNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKL-TYTQQLEDLKRQLEEEVKAKNA 1328

Query: 176  YKFWSQISQGH---LSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR-KSLGSEDSRN 231
                 Q ++     L  +++ + E      RVLS         N E  + ++    D+  
Sbjct: 1329 LAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA-------NSEVAQWRTKYETDAIQ 1381

Query: 232  MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK 291
              E+LE+ +  L    +E  + V    AKC   E  +  L+  + ++++  E        
Sbjct: 1382 RTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERS------ 1435

Query: 292  PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKD--QVKSVM 349
                   NAA   ++ + +     L    +  EE Q   E+ +K    L  +  ++K+  
Sbjct: 1436 -------NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAY 1488

Query: 350  EQNWDEL 356
            E++ + L
Sbjct: 1489 EESLEHL 1495


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 35.4 bits (80), Expect = 0.090
 Identities = 32/140 (22%), Positives = 62/140 (44%), Gaps = 14/140 (10%)

Query: 153 ENLYLVTETLETVKEETLKS-DRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQ 211
           E ++L+T T   V  E L+  D +     +++Q +  Y+ + +       +    Y   Q
Sbjct: 433 EGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQ 492

Query: 212 LVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDL 271
             + + + M K    +  +NMK+  + +ES ++D   E + ++L            RQDL
Sbjct: 493 R-WKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLL------------RQDL 539

Query: 272 EQRVSEVLISGELHMEDPDK 291
            +R  E+    ELH ++  K
Sbjct: 540 MRRQEELRRMEELHNQEMQK 559


>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
          Length = 790

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 47/238 (19%), Positives = 100/238 (42%), Gaps = 29/238 (12%)

Query: 132 TLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKH 191
           T E  K+   L  S   +   + ++++ E     +EE  K     +   +  +  +  + 
Sbjct: 426 TFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQES 485

Query: 192 --KGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNM--KEKLEDMES----VL 243
             +G   ++IPP R+ SY+     F + E  +  +  +  R+   + K ED E+    + 
Sbjct: 486 WDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLS 545

Query: 244 KDLTEEKRKDVL-NSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAG 302
           ++L +EK  +VL +SL +C     +                L + D  +P  S+ +    
Sbjct: 546 RELLDEKEPEVLQDSLDRCYSTPSV---------------YLGLTDSCQPYRSAFY---- 586

Query: 303 VLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSP 360
           VL + R    +D +D + +  E ++    +  + +  LL ++   V++ + D   S+P
Sbjct: 587 VLEQQRIGLAVD-MDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTP 643


>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
           sapiens]
          Length = 790

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 47/238 (19%), Positives = 100/238 (42%), Gaps = 29/238 (12%)

Query: 132 TLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKH 191
           T E  K+   L  S   +   + ++++ E     +EE  K     +   +  +  +  + 
Sbjct: 426 TFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQES 485

Query: 192 --KGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNM--KEKLEDMES----VL 243
             +G   ++IPP R+ SY+     F + E  +  +  +  R+   + K ED E+    + 
Sbjct: 486 WDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLS 545

Query: 244 KDLTEEKRKDVL-NSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAG 302
           ++L +EK  +VL +SL +C     +                L + D  +P  S+ +    
Sbjct: 546 RELLDEKEPEVLQDSLDRCYSTPSV---------------YLGLTDSCQPYRSAFY---- 586

Query: 303 VLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSP 360
           VL + R    +D +D + +  E ++    +  + +  LL ++   V++ + D   S+P
Sbjct: 587 VLEQQRIGLAVD-MDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTP 643


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 32/131 (24%), Positives = 57/131 (43%), Gaps = 15/131 (11%)

Query: 228  DSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHME 287
            D+    E+LE+ +  L    +E  + V    AKC   E  +Q L+  V ++++  E    
Sbjct: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERS-- 1438

Query: 288  DPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKD--QV 345
                       NAA   ++ + +     L    +  EE Q   EA +K +  L  +  +V
Sbjct: 1439 -----------NAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKV 1487

Query: 346  KSVMEQNWDEL 356
            K+V E++ D+L
Sbjct: 1488 KNVYEESLDQL 1498


>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
           sapiens]
          Length = 1631

 Score = 33.9 bits (76), Expect = 0.26
 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 1/95 (1%)

Query: 262 LGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLE 321
           LG+E++   +E   + VLI+  L   D      SSL N A  L E   +    + DALL+
Sbjct: 432 LGQEELFVAVEMLSAVVLINRALEARDASG-FWSSLVNPATGLAEVEGENAQRYFDALLK 490

Query: 322 LSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDEL 356
           L +E+    + L    L     QV +  ++  D +
Sbjct: 491 LRQERGMGEDFLSWNDLQATVSQVNAQTQEETDRV 525


>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
          Length = 968

 Score = 33.5 bits (75), Expect = 0.34
 Identities = 30/118 (25%), Positives = 58/118 (49%), Gaps = 10/118 (8%)

Query: 163 ETVKEETLKSDRQY-KFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR 221
           E  +   L+ DR Y +F  Q+       K + + EV   P +     +KQ +   + T +
Sbjct: 637 EEARRIRLEQDRDYTRFQEQLKL----MKKEVKNEVEKLPRQQRKESMKQKM--EEHTQK 690

Query: 222 KSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCL-GKEDIRQDLEQRVSEV 278
           K L   D   + ++ ED+E  +K LT + R+++ +   +CL  K+++ +D E  + E+
Sbjct: 691 KQLLDRDF--VAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRDREAALWEM 746


>gi|45356151 non-SMC condensin II complex, subunit D3 [Homo sapiens]
          Length = 1498

 Score = 33.5 bits (75), Expect = 0.34
 Identities = 40/167 (23%), Positives = 76/167 (45%), Gaps = 27/167 (16%)

Query: 214  FPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLN----SLAKCLGKEDIRQ 269
            FP  E  ++    +   N + +++  + +L+  T+E+R ++ +    S+  C     +  
Sbjct: 1075 FPQSEREKRLFSLKGKSNKERRMKIYKFLLEHFTDEQRFNITSKICLSILACFADGILPL 1134

Query: 270  DLE-----QRVSEVLISGELHM----EDPDKPLL---SSLFNAAGVLVEARAKAI----- 312
            DL+         EVL S E+ +      PDK LL     +  A  V+ EA+ K I     
Sbjct: 1135 DLDASELLSDTFEVLSSKEIKLLAMRSKPDKDLLMEEDDMALANVVMQEAQKKLISQVQK 1194

Query: 313  LDFLDALLELSEEQQFVAEALEKGTLPLLKD---QVKSVMEQNWDEL 356
             +F++ ++ +    + V   LEK  +P L++    ++ VM+   DEL
Sbjct: 1195 RNFIENIIPIIISLKTV---LEKNKIPALRELMHYLREVMQDYRDEL 1238


>gi|24308219 synaptotagmin IV [Homo sapiens]
          Length = 425

 Score = 33.5 bits (75), Expect = 0.34
 Identities = 34/155 (21%), Positives = 62/155 (40%), Gaps = 7/155 (4%)

Query: 190 KHKGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEE 249
           + K  +    PP + +       ++P     +K  G++D   +K K    ++ L  L  E
Sbjct: 39  QRKSSKSNKTPPYKFVHVLKGVDIYPENLNSKKKFGADDKNEVKNKPAVPKNSL-HLDLE 97

Query: 250 KRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARA 309
           KR D+  +  K   K     DLE    ++ + GE     P+     SL ++  +  E + 
Sbjct: 98  KR-DLNGNFPKTNLKPGSPSDLENATPKLFLEGEKESVSPE-----SLKSSTSLTSEEKQ 151

Query: 310 KAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQ 344
           + +     +L    E + FV    E   LP + +Q
Sbjct: 152 EKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQ 186


>gi|63054866 leucine rich repeat containing 16A [Homo sapiens]
          Length = 1326

 Score = 33.1 bits (74), Expect = 0.45
 Identities = 27/122 (22%), Positives = 60/122 (49%), Gaps = 11/122 (9%)

Query: 186 HLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKD 245
           H    H  +R  T+P    L   + +     ++ +++S+ + +     E+LED+++ +  
Sbjct: 862 HKLADHFSRRGKTLPQQESLEIELAE-----EKPVKRSIITVEELTEIERLEDLDTCMMT 916

Query: 246 LTEEKRKDVLNSLAKCLGKE-DIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVL 304
             + KRK + + + + + +  ++  DL++ + EV I    H+EDP  P L     ++G +
Sbjct: 917 -PKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPI----HIEDPPFPSLRQEKRSSGFI 971

Query: 305 VE 306
            E
Sbjct: 972 SE 973


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 33.1 bits (74), Expect = 0.45
 Identities = 31/143 (21%), Positives = 61/143 (42%), Gaps = 19/143 (13%)

Query: 152  RENLYLVTETLETVKEETLKSDR----------QYKFWSQISQGHLSY-------KHKGQ 194
            RE  Y   E L+  +E+ L+ +R          QY+   ++ Q            +   +
Sbjct: 986  REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045

Query: 195  REVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDV 254
            RE        L    +QL+   +ET R+       R  +E  ++ E +L++  E++R+  
Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ- 1104

Query: 255  LNSLAKCLGKEDIRQDLEQRVSE 277
                 +C  +E+++Q+ EQ + E
Sbjct: 1105 -ERERQCREEEELQQEEEQLLRE 1126


>gi|224586823 coiled-coil domain containing 110 isoform b [Homo
           sapiens]
          Length = 796

 Score = 32.7 bits (73), Expect = 0.58
 Identities = 68/295 (23%), Positives = 120/295 (40%), Gaps = 68/295 (23%)

Query: 100 LPKEITISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSI-----NTREN 154
           LP   T+S     F  +  K+S++ + +      +N K  +E+P + ++I     ++R  
Sbjct: 286 LPFRETVSKFHVHFCRKCKKLSKSEMHRGK----KNEKNNKEIPITGKNITDLKFHSRVP 341

Query: 155 LYLVTETLETVKEETLKSDRQ---YKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQ 211
            Y ++  L+  K E    +RQ    K  S IS+   + K     E  +   + L   +K+
Sbjct: 342 RYTLS-FLDQTKHEMKDKERQPFLVKQGSIISENEKTSKVNSVTEQCVAKIQYLQNYLKE 400

Query: 212 LVFPNKETMRKSLGSED-------------SRNMKEKLEDMESVLKDLTEEK-------- 250
            V   K+ M   L SE+             ++++ +K+E  E  LK+L EEK        
Sbjct: 401 SVQIQKKVME--LESENLNLKSKMKPLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSKLS 458

Query: 251 ------------------RKDVLNSLAKCLGKEDIRQDLE-QRVSEVL--ISGELHMEDP 289
                             + +VL    K L +++I+  LE Q++ E L  +  + H    
Sbjct: 459 KTEEYSKECLKEFKKIISKYNVLQGQNKTLEEKNIQLSLEKQQMMEALDQLKSKEHKTQS 518

Query: 290 DKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQ 344
           D  ++++  N   + +EA    IL   D             E LEK T  LLK++
Sbjct: 519 DMAIVNNENNRMSIEMEAMKTNILLIQDE-----------KEMLEKKTHQLLKEK 562


>gi|22749515 coiled-coil domain containing 110 isoform a [Homo
           sapiens]
          Length = 833

 Score = 32.7 bits (73), Expect = 0.58
 Identities = 68/295 (23%), Positives = 120/295 (40%), Gaps = 68/295 (23%)

Query: 100 LPKEITISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSI-----NTREN 154
           LP   T+S     F  +  K+S++ + +      +N K  +E+P + ++I     ++R  
Sbjct: 323 LPFRETVSKFHVHFCRKCKKLSKSEMHRGK----KNEKNNKEIPITGKNITDLKFHSRVP 378

Query: 155 LYLVTETLETVKEETLKSDRQ---YKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQ 211
            Y ++  L+  K E    +RQ    K  S IS+   + K     E  +   + L   +K+
Sbjct: 379 RYTLS-FLDQTKHEMKDKERQPFLVKQGSIISENEKTSKVNSVTEQCVAKIQYLQNYLKE 437

Query: 212 LVFPNKETMRKSLGSED-------------SRNMKEKLEDMESVLKDLTEEK-------- 250
            V   K+ M   L SE+             ++++ +K+E  E  LK+L EEK        
Sbjct: 438 SVQIQKKVME--LESENLNLKSKMKPLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSKLS 495

Query: 251 ------------------RKDVLNSLAKCLGKEDIRQDLE-QRVSEVL--ISGELHMEDP 289
                             + +VL    K L +++I+  LE Q++ E L  +  + H    
Sbjct: 496 KTEEYSKECLKEFKKIISKYNVLQGQNKTLEEKNIQLSLEKQQMMEALDQLKSKEHKTQS 555

Query: 290 DKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQ 344
           D  ++++  N   + +EA    IL   D             E LEK T  LLK++
Sbjct: 556 DMAIVNNENNRMSIEMEAMKTNILLIQDE-----------KEMLEKKTHQLLKEK 599


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 32.7 bits (73), Expect = 0.58
 Identities = 33/124 (26%), Positives = 65/124 (52%), Gaps = 15/124 (12%)

Query: 217 KETMRKSLGSEDSRNMK--EKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQR 274
           K+T  +SL SE S  +K   KLE+  SVLKD T++ ++++   +      ++ +   +Q+
Sbjct: 682 KQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKM------DEQKNHHQQQ 735

Query: 275 VSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAK------AILDFLDALLELSEEQQF 328
           V  ++   E+ ++  +K L   + N   +L++ R K      A ++ L+A ++ SE +  
Sbjct: 736 VDSIIKEHEVSIQRTEKALKDQI-NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQ 794

Query: 329 VAEA 332
            A A
Sbjct: 795 QASA 798


>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
           sapiens]
          Length = 1185

 Score = 32.7 bits (73), Expect = 0.58
 Identities = 37/179 (20%), Positives = 75/179 (41%), Gaps = 14/179 (7%)

Query: 160 ETLETVKEETLKSDRQY-KFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKE 218
           E L+T +++ +KS+    K    + +     +   +R  T+    + + R    V    +
Sbjct: 285 EDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLND 344

Query: 219 TMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEV 278
            +   + ++DS  M  + ED    L++  E   + +  +L K     ++  +L QRV+ +
Sbjct: 345 KLENEIANKDS--MHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAAL 402

Query: 279 LISGELH--MEDPDKPLLSSLFNAAGVLVEARA---------KAILDFLDALLELSEEQ 326
             + E H  +E+  + + + L      L  AR          K + D +D LL  S E+
Sbjct: 403 SKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNER 461


>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
           sapiens]
          Length = 1202

 Score = 32.7 bits (73), Expect = 0.58
 Identities = 37/179 (20%), Positives = 75/179 (41%), Gaps = 14/179 (7%)

Query: 160 ETLETVKEETLKSDRQY-KFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKE 218
           E L+T +++ +KS+    K    + +     +   +R  T+    + + R    V    +
Sbjct: 285 EDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLND 344

Query: 219 TMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEV 278
            +   + ++DS  M  + ED    L++  E   + +  +L K     ++  +L QRV+ +
Sbjct: 345 KLENEIANKDS--MHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAAL 402

Query: 279 LISGELH--MEDPDKPLLSSLFNAAGVLVEARA---------KAILDFLDALLELSEEQ 326
             + E H  +E+  + + + L      L  AR          K + D +D LL  S E+
Sbjct: 403 SKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNER 461


>gi|110347568 centrosomal protein 152kDa [Homo sapiens]
          Length = 1654

 Score = 32.7 bits (73), Expect = 0.58
 Identities = 43/203 (21%), Positives = 91/203 (44%), Gaps = 33/203 (16%)

Query: 102 KEITISGSFQGFHHQKIKISENRISQQYLATLE--NRKLKRELPFSFRSINTRE-NLYLV 158
           +EIT S +F+G   Q +  +EN      +  L+  N+  +R+L      +N  E  +  +
Sbjct: 210 QEITGSDTFEGLQQQFLGANENSAENMQIIQLQVLNKAKERQLENLIEKLNESERQIRYL 269

Query: 159 TETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPN-RVLSYRVKQLVFPNK 217
              L  +K+E      +      + +    +++  +RE+ +    + L  +++ L    +
Sbjct: 270 NHQLVIIKDE------KDGLTLSLRESQKLFQNGKEREIQLEAQIKALETQIQALKVNEE 323

Query: 218 ETMRKSLGSEDS-RNMKEKLEDM-------------ESVLKDLTEEKRKDVLNSLAKCLG 263
           + ++KS  +E +  ++K++L D+             ES++  LT++  + VL SL K L 
Sbjct: 324 QMIKKSRTTEMALESLKQQLVDLHHSESLQRAREQHESIVMGLTKKYEEQVL-SLQKNLD 382

Query: 264 --------KEDIRQDLEQRVSEV 278
                   +EDI   L+  V ++
Sbjct: 383 ATVTALKEQEDICSRLKDHVKQL 405


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,730,819
Number of Sequences: 37866
Number of extensions: 580136
Number of successful extensions: 2370
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 101
Number of HSP's that attempted gapping in prelim test: 2273
Number of HSP's gapped (non-prelim): 177
length of query: 394
length of database: 18,247,518
effective HSP length: 104
effective length of query: 290
effective length of database: 14,309,454
effective search space: 4149741660
effective search space used: 4149741660
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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