BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|109689711 gasdermin-like isoform 2 [Homo sapiens] (394 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|109689711 gasdermin-like isoform 2 [Homo sapiens] 771 0.0 gi|109689703 gasdermin-like isoform 1 [Homo sapiens] 763 0.0 gi|150456463 gasdermin 1 [Homo sapiens] 131 1e-30 gi|83320070 gasdermin D [Homo sapiens] 85 1e-16 gi|13899221 melanoma-derived leucine zipper, extra-nuclear facto... 49 8e-06 gi|4758154 deafness, autosomal dominant 5 protein isoform a [Hom... 42 7e-04 gi|188536092 deafness, autosomal dominant 5 protein isoform a [H... 42 7e-04 gi|118498362 kinectin 1 isoform b [Homo sapiens] 39 0.006 gi|111607457 deafness, autosomal recessive 59 [Homo sapiens] 38 0.014 gi|118498356 kinectin 1 isoform a [Homo sapiens] 38 0.018 gi|118498368 kinectin 1 isoform c [Homo sapiens] 38 0.018 gi|33620775 kinectin 1 isoform a [Homo sapiens] 38 0.018 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 38 0.018 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 35 0.090 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 35 0.090 gi|156071420 hypothetical protein LOC728912 [Homo sapiens] 34 0.20 gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho... 34 0.20 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 34 0.20 gi|39753961 IQ motif containing GTPase activating protein 3 [Hom... 34 0.26 gi|126362971 serine/threonine kinase 10 [Homo sapiens] 33 0.34 gi|45356151 non-SMC condensin II complex, subunit D3 [Homo sapiens] 33 0.34 gi|24308219 synaptotagmin IV [Homo sapiens] 33 0.34 gi|63054866 leucine rich repeat containing 16A [Homo sapiens] 33 0.45 gi|148746195 trichohyalin [Homo sapiens] 33 0.45 gi|224586823 coiled-coil domain containing 110 isoform b [Homo s... 33 0.58 gi|22749515 coiled-coil domain containing 110 isoform a [Homo sa... 33 0.58 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 33 0.58 gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 33 0.58 gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 33 0.58 gi|110347568 centrosomal protein 152kDa [Homo sapiens] 33 0.58 >gi|109689711 gasdermin-like isoform 2 [Homo sapiens] Length = 394 Score = 771 bits (1992), Expect = 0.0 Identities = 394/394 (100%), Positives = 394/394 (100%) Query: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD Sbjct: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60 Query: 61 ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120 ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI Sbjct: 61 ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120 Query: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS Sbjct: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180 Query: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDME 240 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDME Sbjct: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDME 240 Query: 241 SVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNA 300 SVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNA Sbjct: 241 SVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNA 300 Query: 301 AGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSP 360 AGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSP Sbjct: 301 AGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSP 360 Query: 361 PDMDYDPEARILCALYVVVSILLELAEGPTSVSS 394 PDMDYDPEARILCALYVVVSILLELAEGPTSVSS Sbjct: 361 PDMDYDPEARILCALYVVVSILLELAEGPTSVSS 394 >gi|109689703 gasdermin-like isoform 1 [Homo sapiens] Length = 403 Score = 763 bits (1969), Expect = 0.0 Identities = 393/403 (97%), Positives = 394/403 (97%), Gaps = 9/403 (2%) Query: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD Sbjct: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHYTTGLTLMD 60 Query: 61 ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120 ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI Sbjct: 61 ILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIKI 120 Query: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS Sbjct: 121 SENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWS 180 Query: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR---------KSLGSEDSRN 231 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETM+ KSLGSEDSRN Sbjct: 181 QISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMKKDGASSCLGKSLGSEDSRN 240 Query: 232 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK 291 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK Sbjct: 241 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK 300 Query: 292 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ 351 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ Sbjct: 301 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQ 360 Query: 352 NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS 394 NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS Sbjct: 361 NWDELASSPPDMDYDPEARILCALYVVVSILLELAEGPTSVSS 403 >gi|150456463 gasdermin 1 [Homo sapiens] Length = 445 Score = 131 bits (329), Expect = 1e-30 Identities = 129/462 (27%), Positives = 214/462 (46%), Gaps = 97/462 (20%) Query: 3 SVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRT---FFGCRHYTTGLTLM 59 ++FE +TR + ++++ GD+ + SL+D RF F LV KR F+G R+ T TL+ Sbjct: 2 TMFENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTLL 61 Query: 60 DILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHHQKIK 119 D+L+ G D D+G G K + +D+ E V +PK + + G+ + ++ Sbjct: 62 DVLEP-GSSPSDPTDTGNFGFK------NMLDTRVEGDVDVPKTVKVKGTAGLSQNSTLE 114 Query: 120 ISENRISQQYLATLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYK-- 177 + ++ + L T++ RKL + PF + ENLY+V E +ETV+E TL+ + + Sbjct: 115 VQTLSVAPKALETVQERKLAADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEAC 174 Query: 178 ----FWSQIS-QGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKE-------------- 218 F++ + QG +++K VTIP VL++RV+QL+ K+ Sbjct: 175 FSLPFFAPLGLQGSINHK----EAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQT 230 Query: 219 --------------TMRKSLGS--EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCL 262 +G E R +KE+++ ++ L+ + +L+SL+K L Sbjct: 231 FPPGEKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLL 290 Query: 263 GKEDIRQDLEQRVSEVLISG-ELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLE 321 GK+ QDLE + L G E+ +E K +L L + AIL F+ AL E Sbjct: 291 GKKKELQDLELALEGALDKGHEVTLEALPKDVL---------LSKEAVGAILYFVGALTE 341 Query: 322 LSEEQQ-FVAEALEKGTLPLLKDQVKSVMEQNW--------------------------- 353 LSE QQ + +++EK LP+ V+S MEQN+ Sbjct: 342 LSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTE 401 Query: 354 -------DELASSPPDMDYDPEA-RILCALYVVVSILLELAE 387 E+ S P +DP+ LCALY +S+L +L + Sbjct: 402 ALVGLSGLEVQRSGPQYMWDPDTLPRLCALYAGLSLLQQLTK 443 >gi|83320070 gasdermin D [Homo sapiens] Length = 484 Score = 84.7 bits (208), Expect = 1e-16 Identities = 120/494 (24%), Positives = 206/494 (41%), Gaps = 116/494 (23%) Query: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRT---FFGCRHYTTGLT 57 M S FE + R VV+E+D GG+ I V SL + F+ + LV K + F+ R+ L+ Sbjct: 1 MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLS 60 Query: 58 LMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDS--TGELIVRLPKEITISGSFQGFHH 115 + DIL+ D + ++ G F D +D G + + P + I+G Sbjct: 61 IKDILEPDAAE--PDVQRG-----RSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDS 113 Query: 116 QKIKISENRIS---QQYLATLENRKLKRELPFSFRSINTR-ENLYLVTETLETVKEETLK 171 ++ +S + L R L++ + + +R +N+Y+VTE L+T KE + Sbjct: 114 SSTSMNVYSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVT 173 Query: 172 SDRQYKFWSQIS-----------QGHLSYKHKGQREVTIPPNRVLSYRVKQLV------- 213 + + + S QGHLS K + VTIP L++RV QLV Sbjct: 174 RTHKREGSGRFSLPGATCLQGEGQGHLSQK----KTVTIPSGSTLAFRVAQLVIDSDLDV 229 Query: 214 --FPNKE---------------------------TMRKSLG-------------SEDSRN 231 FP+K+ +M + L +ED + Sbjct: 230 LLFPDKKQRTFQPPATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQG 289 Query: 232 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELH-MEDPD 290 ++ ++E + L+ L E + +L L L + + LE+ + + G + ++ P Sbjct: 290 LRAEVETISKELELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPA 349 Query: 291 KPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQ-QFVAEALEKGTLPLLKDQVKSVM 349 +L L ++G+LV A ++ L AL LSE Q + +AEALE TL + V S++ Sbjct: 350 GAVLECLVLSSGMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLL 409 Query: 350 EQN--WD-------------------------------ELASSPPDMDYDPEAR-ILCAL 375 EQ+ W EL P + ++P+A+ +CAL Sbjct: 410 EQSAPWQERSTMSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQAQGRMCAL 469 Query: 376 YVVVSILLELAEGP 389 Y +++L L++ P Sbjct: 470 YASLALLSGLSQEP 483 >gi|13899221 melanoma-derived leucine zipper, extra-nuclear factor [Homo sapiens] Length = 508 Score = 48.9 bits (115), Expect = 8e-06 Identities = 60/256 (23%), Positives = 110/256 (42%), Gaps = 22/256 (8%) Query: 1 MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKR----TFFGCRHYT-TG 55 M S+ E I++ +VKE+ + D+ V+ L+ A + R F ++ +K+ +F+ Y Sbjct: 1 MPSMLERISKNLVKEIGSK-DLTPVKYLLSATKLRQFVILRKKKDSRSSFWEQSDYVPVE 59 Query: 56 LTLMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDSTGELIVRLPKEITISGSFQGFHH 115 +L DIL+ L++ + G F + ++ V + E+++SG H Sbjct: 60 FSLNDILEPSSSV----LETVVTGP-FHFSDIMIQKHKADMGVNVGIEVSVSGEASVDHG 114 Query: 116 QKIKISENRISQQYLATLENRKLKRELPFSFRSINTR-ENLYLVTETLETVKEETLKSDR 174 ++ I L + RKL P + R +NLY+VTE +E + L Sbjct: 115 CSLEFQIVTIPSPNLEDFQKRKLLDPEPSFLKECRRRGDNLYVVTEAVELINNTVLYDSS 174 Query: 175 QYKFWSQISQGHLSYKHKGQRE--------VTIPPNRVLSYRVKQLVFPNKETMRKSLGS 226 +I+ K +GQ E +T+ V++Y+ KQLV K + Sbjct: 175 SVNILGKIALWITYGKGQGQGESLRVKKKALTLQKGMVMAYKRKQLVIKEKAILISD--D 232 Query: 227 EDSRNMKEKLEDMESV 242 ++ R +++ E E V Sbjct: 233 DEQRTFQDEYEISEMV 248 >gi|4758154 deafness, autosomal dominant 5 protein isoform a [Homo sapiens] Length = 496 Score = 42.4 bits (98), Expect = 7e-04 Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 5/66 (7%) Query: 4 VFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGC----RHYTTGLTLM 59 +F + TR ++E+DA GD+IAV +L D+D+ + LV +K+ F+ C ++ LTL Sbjct: 1 MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFW-CWQRPKYQFLSLTLG 59 Query: 60 DILDTD 65 D+L D Sbjct: 60 DVLIED 65 >gi|188536092 deafness, autosomal dominant 5 protein isoform a [Homo sapiens] Length = 496 Score = 42.4 bits (98), Expect = 7e-04 Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 5/66 (7%) Query: 4 VFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGC----RHYTTGLTLM 59 +F + TR ++E+DA GD+IAV +L D+D+ + LV +K+ F+ C ++ LTL Sbjct: 1 MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFW-CWQRPKYQFLSLTLG 59 Query: 60 DILDTD 65 D+L D Sbjct: 60 DVLIED 65 >gi|118498362 kinectin 1 isoform b [Homo sapiens] Length = 1306 Score = 39.3 bits (90), Expect = 0.006 Identities = 37/154 (24%), Positives = 83/154 (53%), Gaps = 17/154 (11%) Query: 216 NKE-TMRKSLGS--EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLE 272 NKE T++ S+ S ++ +N+ + E+ + +K + EEK KD+ N+ K L +D++++ E Sbjct: 826 NKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENE 882 Query: 273 QRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQ 327 + V + ++++ +S F ++++ + L L+A+L +LS + Q Sbjct: 883 SLKAHVQEVAQHNLKEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQ 938 Query: 328 FVAEALEKGTLPLLKDQVKSVMEQNWDELASSPP 361 + + ++ L K Q++ + +QN+ + +S PP Sbjct: 939 LLQDVQDEN--KLFKSQIEQLKQQNYQQASSFPP 970 Score = 28.9 bits (63), Expect = 8.4 Identities = 32/139 (23%), Positives = 62/139 (44%), Gaps = 12/139 (8%) Query: 162 LETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR 221 L VKE+ + + K Q++Q ++ K + +T +R+ + + VF NK + Sbjct: 341 LAAVKEDAAATKDRCK---QLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVS 397 Query: 222 KSLGSEDSRNMKEKLEDMESVLKDLTEEK---RKDVLNSLAKCLGKED-----IRQDLEQ 273 + ++ E ME+ + L +E R V N+ + K+ +RQD + Sbjct: 398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYAR 457 Query: 274 RVSEVL-ISGELHMEDPDK 291 V+E+ +G+L E+ K Sbjct: 458 LVNELTEKTGKLQQEEVQK 476 >gi|111607457 deafness, autosomal recessive 59 [Homo sapiens] Length = 352 Score = 38.1 bits (87), Expect = 0.014 Identities = 38/147 (25%), Positives = 64/147 (43%), Gaps = 23/147 (15%) Query: 4 VFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRTFFGCRHY---TTGLTLMD 60 +F T+ VK++ GG ++ V SL +AD+++ LV +K+ F Y +T TL D Sbjct: 1 MFAAATKSFVKQVGDGGRLVPVPSLSEADKYQPLSLVVKKKRCFLFPRYKFTSTPFTLKD 60 Query: 61 ILDTDGD-----------KWLDELDSGLQGQKAEFQILD---NVDSTGELIVR------L 100 IL D + + DE D L G++ + D NV + + V+ Sbjct: 61 ILLGDREISAGISSYQLLNYEDESDVSLYGRRGNHIVNDVGINVAGSDSIAVKASFGIVT 120 Query: 101 PKEITISGSFQGFHHQKIKISENRISQ 127 E+ +S + +KI + I Q Sbjct: 121 KHEVEVSTLLKEITTRKINFDHSLIRQ 147 >gi|118498356 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 37.7 bits (86), Expect = 0.018 Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 14/140 (10%) Query: 227 EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHM 286 ++ +N+ + E+ + +K + EEK KD+ N+ K L +D++++ E + V + ++ Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENESLKAHVQEVAQHNL 919 Query: 287 EDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQFVAEALEKGTLPLL 341 ++ +S F ++++ + L L+A+L +LS + Q + + ++ L Sbjct: 920 KEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQLLQDVQDEN--KLF 973 Query: 342 KDQVKSVMEQNWDELASSPP 361 K Q++ + +QN+ + +S PP Sbjct: 974 KSQIEQLKQQNYQQASSFPP 993 Score = 28.9 bits (63), Expect = 8.4 Identities = 32/139 (23%), Positives = 62/139 (44%), Gaps = 12/139 (8%) Query: 162 LETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR 221 L VKE+ + + K Q++Q ++ K + +T +R+ + + VF NK + Sbjct: 341 LAAVKEDAAATKDRCK---QLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVS 397 Query: 222 KSLGSEDSRNMKEKLEDMESVLKDLTEEK---RKDVLNSLAKCLGKED-----IRQDLEQ 273 + ++ E ME+ + L +E R V N+ + K+ +RQD + Sbjct: 398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYAR 457 Query: 274 RVSEVL-ISGELHMEDPDK 291 V+E+ +G+L E+ K Sbjct: 458 LVNELTEKTGKLQQEEVQK 476 >gi|118498368 kinectin 1 isoform c [Homo sapiens] Length = 1300 Score = 37.7 bits (86), Expect = 0.018 Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 14/140 (10%) Query: 227 EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHM 286 ++ +N+ + E+ + +K + EEK KD+ N+ K L +D++++ E + V + ++ Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENESLKAHVQEVAQHNL 919 Query: 287 EDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQFVAEALEKGTLPLL 341 ++ +S F ++++ + L L+A+L +LS + Q + + ++ L Sbjct: 920 KEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQLLQDVQDEN--KLF 973 Query: 342 KDQVKSVMEQNWDELASSPP 361 K Q++ + +QN+ + +S PP Sbjct: 974 KSQIEQLKQQNYQQASSFPP 993 Score = 28.9 bits (63), Expect = 8.4 Identities = 32/139 (23%), Positives = 62/139 (44%), Gaps = 12/139 (8%) Query: 162 LETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR 221 L VKE+ + + K Q++Q ++ K + +T +R+ + + VF NK + Sbjct: 341 LAAVKEDAAATKDRCK---QLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVS 397 Query: 222 KSLGSEDSRNMKEKLEDMESVLKDLTEEK---RKDVLNSLAKCLGKED-----IRQDLEQ 273 + ++ E ME+ + L +E R V N+ + K+ +RQD + Sbjct: 398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYAR 457 Query: 274 RVSEVL-ISGELHMEDPDK 291 V+E+ +G+L E+ K Sbjct: 458 LVNELTEKTGKLQQEEVQK 476 >gi|33620775 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 37.7 bits (86), Expect = 0.018 Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 14/140 (10%) Query: 227 EDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHM 286 ++ +N+ + E+ + +K + EEK KD+ N+ K L +D++++ E + V + ++ Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANT-GKWL--QDLQEENESLKAHVQEVAQHNL 919 Query: 287 EDPDKPLLSSLFNAAGVLVEARAKAILDFLDALL-----ELSEEQQFVAEALEKGTLPLL 341 ++ +S F ++++ + L L+A+L +LS + Q + + ++ L Sbjct: 920 KEASS---ASQFEELEIVLKEKENE-LKRLEAMLKERESDLSSKTQLLQDVQDEN--KLF 973 Query: 342 KDQVKSVMEQNWDELASSPP 361 K Q++ + +QN+ + +S PP Sbjct: 974 KSQIEQLKQQNYQQASSFPP 993 Score = 28.9 bits (63), Expect = 8.4 Identities = 32/139 (23%), Positives = 62/139 (44%), Gaps = 12/139 (8%) Query: 162 LETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR 221 L VKE+ + + K Q++Q ++ K + +T +R+ + + VF NK + Sbjct: 341 LAAVKEDAAATKDRCK---QLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVS 397 Query: 222 KSLGSEDSRNMKEKLEDMESVLKDLTEEK---RKDVLNSLAKCLGKED-----IRQDLEQ 273 + ++ E ME+ + L +E R V N+ + K+ +RQD + Sbjct: 398 YQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYAR 457 Query: 274 RVSEVL-ISGELHMEDPDK 291 V+E+ +G+L E+ K Sbjct: 458 LVNELTEKTGKLQQEEVQK 476 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 37.7 bits (86), Expect = 0.018 Identities = 65/285 (22%), Positives = 135/285 (47%), Gaps = 38/285 (13%) Query: 78 QGQKAEFQILDNVDSTGELIVRLPKEI-TISGSFQGFHHQKIKISENRISQQYLATLENR 136 Q +K E Q+ N++ + + K+I + G + QK ++ EN++ QQ + Sbjct: 949 QNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTEL-ENKLQQQLTQAAQEL 1007 Query: 137 KLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQRE 196 ++E I+ +N Y ++ ET K+ L+SD Y S++ K + + Sbjct: 1008 AAEKE------KISVLQNNY--EKSQETFKQ--LQSDF-YGRESELLATRQDLKSV-EEK 1055 Query: 197 VTIPPNRVLSYRVKQLVFPNK-----ETMRKSLGSEDSRNMKEKLEDMESVLKDLTEE-- 249 +++ ++S R Q+ NK +T + +L +DS +++L++ L+D+ +E Sbjct: 1056 LSLAQEDLISNR-NQIGNQNKLIQELKTAKATL-EQDSAKKEQQLQERCKALQDIQKEKS 1113 Query: 250 -KRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEAR 308 K K+++N +K E+I+ E+ ++++ + H + K +++L +A +L++ + Sbjct: 1114 LKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKE-ITNLKDAKQLLIQQK 1172 Query: 309 AKAILDFLDALLELSEEQQFVAEAL--EKGTLPLLKDQVKSVMEQ 351 LEL + + A+ EK +LKDQVK E+ Sbjct: 1173 -----------LELQGKADSLKAAVEQEKRNQQILKDQVKKEEEE 1206 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 35.4 bits (80), Expect = 0.090 Identities = 68/307 (22%), Positives = 125/307 (40%), Gaps = 41/307 (13%) Query: 70 LDELDSGLQGQKAEFQI-LDNVDSTGELIVR----LPKEITISGSFQGFHHQKIKISENR 124 L + L+ +K+EF++ LD+V S E I++ L K H K + ++ Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269 Query: 125 I----SQQYLATLENRKLKRELPFSFRSIN--TRENLYLVTETLETVK---EETLKSDRQ 175 + SQ+ EN +L R+L I+ TR L T+ LE +K EE +K+ Sbjct: 1270 VNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKL-TYTQQLEDLKRQLEEEVKAKNA 1328 Query: 176 YKFWSQISQGH---LSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR-KSLGSEDSRN 231 Q ++ L +++ + E RVLS N E + ++ D+ Sbjct: 1329 LAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA-------NSEVAQWRTKYETDAIQ 1381 Query: 232 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDK 291 E+LE+ + L +E + V AKC E + L+ + ++++ E Sbjct: 1382 RTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERS------ 1435 Query: 292 PLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKD--QVKSVM 349 NAA ++ + + L + EE Q E+ +K L + ++K+ Sbjct: 1436 -------NAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAY 1488 Query: 350 EQNWDEL 356 E++ + L Sbjct: 1489 EESLEHL 1495 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 35.4 bits (80), Expect = 0.090 Identities = 32/140 (22%), Positives = 62/140 (44%), Gaps = 14/140 (10%) Query: 153 ENLYLVTETLETVKEETLKS-DRQYKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQ 211 E ++L+T T V E L+ D + +++Q + Y+ + + + Y Q Sbjct: 433 EGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQ 492 Query: 212 LVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDL 271 + + + M K + +NMK+ + +ES ++D E + ++L RQDL Sbjct: 493 R-WKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLL------------RQDL 539 Query: 272 EQRVSEVLISGELHMEDPDK 291 +R E+ ELH ++ K Sbjct: 540 MRRQEELRRMEELHNQEMQK 559 >gi|156071420 hypothetical protein LOC728912 [Homo sapiens] Length = 790 Score = 34.3 bits (77), Expect = 0.20 Identities = 47/238 (19%), Positives = 100/238 (42%), Gaps = 29/238 (12%) Query: 132 TLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKH 191 T E K+ L S + + ++++ E +EE K + + + + + Sbjct: 426 TFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQES 485 Query: 192 --KGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNM--KEKLEDMES----VL 243 +G ++IPP R+ SY+ F + E + + + R+ + K ED E+ + Sbjct: 486 WDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLS 545 Query: 244 KDLTEEKRKDVL-NSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAG 302 ++L +EK +VL +SL +C + L + D +P S+ + Sbjct: 546 RELLDEKEPEVLQDSLDRCYSTPSV---------------YLGLTDSCQPYRSAFY---- 586 Query: 303 VLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSP 360 VL + R +D +D + + E ++ + + + LL ++ V++ + D S+P Sbjct: 587 VLEQQRIGLAVD-MDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTP 643 >gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo sapiens] Length = 790 Score = 34.3 bits (77), Expect = 0.20 Identities = 47/238 (19%), Positives = 100/238 (42%), Gaps = 29/238 (12%) Query: 132 TLENRKLKRELPFSFRSINTRENLYLVTETLETVKEETLKSDRQYKFWSQISQGHLSYKH 191 T E K+ L S + + ++++ E +EE K + + + + + Sbjct: 426 TFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQES 485 Query: 192 --KGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNM--KEKLEDMES----VL 243 +G ++IPP R+ SY+ F + E + + + R+ + K ED E+ + Sbjct: 486 WDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLS 545 Query: 244 KDLTEEKRKDVL-NSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAG 302 ++L +EK +VL +SL +C + L + D +P S+ + Sbjct: 546 RELLDEKEPEVLQDSLDRCYSTPSV---------------YLGLTDSCQPYRSAFY---- 586 Query: 303 VLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDELASSP 360 VL + R +D +D + + E ++ + + + LL ++ V++ + D S+P Sbjct: 587 VLEQQRIGLAVD-MDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTP 643 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 34.3 bits (77), Expect = 0.20 Identities = 32/131 (24%), Positives = 57/131 (43%), Gaps = 15/131 (11%) Query: 228 DSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHME 287 D+ E+LE+ + L +E + V AKC E +Q L+ V ++++ E Sbjct: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERS-- 1438 Query: 288 DPDKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKD--QV 345 NAA ++ + + L + EE Q EA +K + L + +V Sbjct: 1439 -----------NAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKV 1487 Query: 346 KSVMEQNWDEL 356 K+V E++ D+L Sbjct: 1488 KNVYEESLDQL 1498 >gi|39753961 IQ motif containing GTPase activating protein 3 [Homo sapiens] Length = 1631 Score = 33.9 bits (76), Expect = 0.26 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 1/95 (1%) Query: 262 LGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAKAILDFLDALLE 321 LG+E++ +E + VLI+ L D SSL N A L E + + DALL+ Sbjct: 432 LGQEELFVAVEMLSAVVLINRALEARDASG-FWSSLVNPATGLAEVEGENAQRYFDALLK 490 Query: 322 LSEEQQFVAEALEKGTLPLLKDQVKSVMEQNWDEL 356 L +E+ + L L QV + ++ D + Sbjct: 491 LRQERGMGEDFLSWNDLQATVSQVNAQTQEETDRV 525 >gi|126362971 serine/threonine kinase 10 [Homo sapiens] Length = 968 Score = 33.5 bits (75), Expect = 0.34 Identities = 30/118 (25%), Positives = 58/118 (49%), Gaps = 10/118 (8%) Query: 163 ETVKEETLKSDRQY-KFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMR 221 E + L+ DR Y +F Q+ K + + EV P + +KQ + + T + Sbjct: 637 EEARRIRLEQDRDYTRFQEQLKL----MKKEVKNEVEKLPRQQRKESMKQKM--EEHTQK 690 Query: 222 KSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCL-GKEDIRQDLEQRVSEV 278 K L D + ++ ED+E +K LT + R+++ + +CL K+++ +D E + E+ Sbjct: 691 KQLLDRDF--VAKQKEDLELAMKRLTTDNRREICDKERECLMKKQELLRDREAALWEM 746 >gi|45356151 non-SMC condensin II complex, subunit D3 [Homo sapiens] Length = 1498 Score = 33.5 bits (75), Expect = 0.34 Identities = 40/167 (23%), Positives = 76/167 (45%), Gaps = 27/167 (16%) Query: 214 FPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLN----SLAKCLGKEDIRQ 269 FP E ++ + N + +++ + +L+ T+E+R ++ + S+ C + Sbjct: 1075 FPQSEREKRLFSLKGKSNKERRMKIYKFLLEHFTDEQRFNITSKICLSILACFADGILPL 1134 Query: 270 DLE-----QRVSEVLISGELHM----EDPDKPLL---SSLFNAAGVLVEARAKAI----- 312 DL+ EVL S E+ + PDK LL + A V+ EA+ K I Sbjct: 1135 DLDASELLSDTFEVLSSKEIKLLAMRSKPDKDLLMEEDDMALANVVMQEAQKKLISQVQK 1194 Query: 313 LDFLDALLELSEEQQFVAEALEKGTLPLLKD---QVKSVMEQNWDEL 356 +F++ ++ + + V LEK +P L++ ++ VM+ DEL Sbjct: 1195 RNFIENIIPIIISLKTV---LEKNKIPALRELMHYLREVMQDYRDEL 1238 >gi|24308219 synaptotagmin IV [Homo sapiens] Length = 425 Score = 33.5 bits (75), Expect = 0.34 Identities = 34/155 (21%), Positives = 62/155 (40%), Gaps = 7/155 (4%) Query: 190 KHKGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEE 249 + K + PP + + ++P +K G++D +K K ++ L L E Sbjct: 39 QRKSSKSNKTPPYKFVHVLKGVDIYPENLNSKKKFGADDKNEVKNKPAVPKNSL-HLDLE 97 Query: 250 KRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARA 309 KR D+ + K K DLE ++ + GE P+ SL ++ + E + Sbjct: 98 KR-DLNGNFPKTNLKPGSPSDLENATPKLFLEGEKESVSPE-----SLKSSTSLTSEEKQ 151 Query: 310 KAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQ 344 + + +L E + FV E LP + +Q Sbjct: 152 EKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQ 186 >gi|63054866 leucine rich repeat containing 16A [Homo sapiens] Length = 1326 Score = 33.1 bits (74), Expect = 0.45 Identities = 27/122 (22%), Positives = 60/122 (49%), Gaps = 11/122 (9%) Query: 186 HLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKD 245 H H +R T+P L + + ++ +++S+ + + E+LED+++ + Sbjct: 862 HKLADHFSRRGKTLPQQESLEIELAE-----EKPVKRSIITVEELTEIERLEDLDTCMMT 916 Query: 246 LTEEKRKDVLNSLAKCLGKE-DIRQDLEQRVSEVLISGELHMEDPDKPLLSSLFNAAGVL 304 + KRK + + + + + + ++ DL++ + EV I H+EDP P L ++G + Sbjct: 917 -PKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPI----HIEDPPFPSLRQEKRSSGFI 971 Query: 305 VE 306 E Sbjct: 972 SE 973 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 33.1 bits (74), Expect = 0.45 Identities = 31/143 (21%), Positives = 61/143 (42%), Gaps = 19/143 (13%) Query: 152 RENLYLVTETLETVKEETLKSDR----------QYKFWSQISQGHLSY-------KHKGQ 194 RE Y E L+ +E+ L+ +R QY+ ++ Q + + Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045 Query: 195 REVTIPPNRVLSYRVKQLVFPNKETMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDV 254 RE L +QL+ +ET R+ R +E ++ E +L++ E++R+ Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ- 1104 Query: 255 LNSLAKCLGKEDIRQDLEQRVSE 277 +C +E+++Q+ EQ + E Sbjct: 1105 -ERERQCREEEELQQEEEQLLRE 1126 >gi|224586823 coiled-coil domain containing 110 isoform b [Homo sapiens] Length = 796 Score = 32.7 bits (73), Expect = 0.58 Identities = 68/295 (23%), Positives = 120/295 (40%), Gaps = 68/295 (23%) Query: 100 LPKEITISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSI-----NTREN 154 LP T+S F + K+S++ + + +N K +E+P + ++I ++R Sbjct: 286 LPFRETVSKFHVHFCRKCKKLSKSEMHRGK----KNEKNNKEIPITGKNITDLKFHSRVP 341 Query: 155 LYLVTETLETVKEETLKSDRQ---YKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQ 211 Y ++ L+ K E +RQ K S IS+ + K E + + L +K+ Sbjct: 342 RYTLS-FLDQTKHEMKDKERQPFLVKQGSIISENEKTSKVNSVTEQCVAKIQYLQNYLKE 400 Query: 212 LVFPNKETMRKSLGSED-------------SRNMKEKLEDMESVLKDLTEEK-------- 250 V K+ M L SE+ ++++ +K+E E LK+L EEK Sbjct: 401 SVQIQKKVME--LESENLNLKSKMKPLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSKLS 458 Query: 251 ------------------RKDVLNSLAKCLGKEDIRQDLE-QRVSEVL--ISGELHMEDP 289 + +VL K L +++I+ LE Q++ E L + + H Sbjct: 459 KTEEYSKECLKEFKKIISKYNVLQGQNKTLEEKNIQLSLEKQQMMEALDQLKSKEHKTQS 518 Query: 290 DKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQ 344 D ++++ N + +EA IL D E LEK T LLK++ Sbjct: 519 DMAIVNNENNRMSIEMEAMKTNILLIQDE-----------KEMLEKKTHQLLKEK 562 >gi|22749515 coiled-coil domain containing 110 isoform a [Homo sapiens] Length = 833 Score = 32.7 bits (73), Expect = 0.58 Identities = 68/295 (23%), Positives = 120/295 (40%), Gaps = 68/295 (23%) Query: 100 LPKEITISGSFQGFHHQKIKISENRISQQYLATLENRKLKRELPFSFRSI-----NTREN 154 LP T+S F + K+S++ + + +N K +E+P + ++I ++R Sbjct: 323 LPFRETVSKFHVHFCRKCKKLSKSEMHRGK----KNEKNNKEIPITGKNITDLKFHSRVP 378 Query: 155 LYLVTETLETVKEETLKSDRQ---YKFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQ 211 Y ++ L+ K E +RQ K S IS+ + K E + + L +K+ Sbjct: 379 RYTLS-FLDQTKHEMKDKERQPFLVKQGSIISENEKTSKVNSVTEQCVAKIQYLQNYLKE 437 Query: 212 LVFPNKETMRKSLGSED-------------SRNMKEKLEDMESVLKDLTEEK-------- 250 V K+ M L SE+ ++++ +K+E E LK+L EEK Sbjct: 438 SVQIQKKVME--LESENLNLKSKMKPLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSKLS 495 Query: 251 ------------------RKDVLNSLAKCLGKEDIRQDLE-QRVSEVL--ISGELHMEDP 289 + +VL K L +++I+ LE Q++ E L + + H Sbjct: 496 KTEEYSKECLKEFKKIISKYNVLQGQNKTLEEKNIQLSLEKQQMMEALDQLKSKEHKTQS 555 Query: 290 DKPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQQFVAEALEKGTLPLLKDQ 344 D ++++ N + +EA IL D E LEK T LLK++ Sbjct: 556 DMAIVNNENNRMSIEMEAMKTNILLIQDE-----------KEMLEKKTHQLLKEK 599 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 32.7 bits (73), Expect = 0.58 Identities = 33/124 (26%), Positives = 65/124 (52%), Gaps = 15/124 (12%) Query: 217 KETMRKSLGSEDSRNMK--EKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQR 274 K+T +SL SE S +K KLE+ SVLKD T++ ++++ + ++ + +Q+ Sbjct: 682 KQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKM------DEQKNHHQQQ 735 Query: 275 VSEVLISGELHMEDPDKPLLSSLFNAAGVLVEARAK------AILDFLDALLELSEEQQF 328 V ++ E+ ++ +K L + N +L++ R K A ++ L+A ++ SE + Sbjct: 736 VDSIIKEHEVSIQRTEKALKDQI-NQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQ 794 Query: 329 VAEA 332 A A Sbjct: 795 QASA 798 >gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sapiens] Length = 1185 Score = 32.7 bits (73), Expect = 0.58 Identities = 37/179 (20%), Positives = 75/179 (41%), Gaps = 14/179 (7%) Query: 160 ETLETVKEETLKSDRQY-KFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKE 218 E L+T +++ +KS+ K + + + +R T+ + + R V + Sbjct: 285 EDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLND 344 Query: 219 TMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEV 278 + + ++DS M + ED L++ E + + +L K ++ +L QRV+ + Sbjct: 345 KLENEIANKDS--MHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAAL 402 Query: 279 LISGELH--MEDPDKPLLSSLFNAAGVLVEARA---------KAILDFLDALLELSEEQ 326 + E H +E+ + + + L L AR K + D +D LL S E+ Sbjct: 403 SKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNER 461 >gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sapiens] Length = 1202 Score = 32.7 bits (73), Expect = 0.58 Identities = 37/179 (20%), Positives = 75/179 (41%), Gaps = 14/179 (7%) Query: 160 ETLETVKEETLKSDRQY-KFWSQISQGHLSYKHKGQREVTIPPNRVLSYRVKQLVFPNKE 218 E L+T +++ +KS+ K + + + +R T+ + + R V + Sbjct: 285 EDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLND 344 Query: 219 TMRKSLGSEDSRNMKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEV 278 + + ++DS M + ED L++ E + + +L K ++ +L QRV+ + Sbjct: 345 KLENEIANKDS--MHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAAL 402 Query: 279 LISGELH--MEDPDKPLLSSLFNAAGVLVEARA---------KAILDFLDALLELSEEQ 326 + E H +E+ + + + L L AR K + D +D LL S E+ Sbjct: 403 SKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNER 461 >gi|110347568 centrosomal protein 152kDa [Homo sapiens] Length = 1654 Score = 32.7 bits (73), Expect = 0.58 Identities = 43/203 (21%), Positives = 91/203 (44%), Gaps = 33/203 (16%) Query: 102 KEITISGSFQGFHHQKIKISENRISQQYLATLE--NRKLKRELPFSFRSINTRE-NLYLV 158 +EIT S +F+G Q + +EN + L+ N+ +R+L +N E + + Sbjct: 210 QEITGSDTFEGLQQQFLGANENSAENMQIIQLQVLNKAKERQLENLIEKLNESERQIRYL 269 Query: 159 TETLETVKEETLKSDRQYKFWSQISQGHLSYKHKGQREVTIPPN-RVLSYRVKQLVFPNK 217 L +K+E + + + +++ +RE+ + + L +++ L + Sbjct: 270 NHQLVIIKDE------KDGLTLSLRESQKLFQNGKEREIQLEAQIKALETQIQALKVNEE 323 Query: 218 ETMRKSLGSEDS-RNMKEKLEDM-------------ESVLKDLTEEKRKDVLNSLAKCLG 263 + ++KS +E + ++K++L D+ ES++ LT++ + VL SL K L Sbjct: 324 QMIKKSRTTEMALESLKQQLVDLHHSESLQRAREQHESIVMGLTKKYEEQVL-SLQKNLD 382 Query: 264 --------KEDIRQDLEQRVSEV 278 +EDI L+ V ++ Sbjct: 383 ATVTALKEQEDICSRLKDHVKQL 405 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.134 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,730,819 Number of Sequences: 37866 Number of extensions: 580136 Number of successful extensions: 2370 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 8 Number of HSP's successfully gapped in prelim test: 101 Number of HSP's that attempted gapping in prelim test: 2273 Number of HSP's gapped (non-prelim): 177 length of query: 394 length of database: 18,247,518 effective HSP length: 104 effective length of query: 290 effective length of database: 14,309,454 effective search space: 4149741660 effective search space used: 4149741660 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.