Guide to the Human Genome
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Search of human proteins with 109452597

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109452597 chromosome 10 open reading frame 46 [Homo sapiens]
         (369 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109452597 chromosome 10 open reading frame 46 [Homo sapiens]       747   0.0  
gi|4503165 cullin 3 [Homo sapiens]                                     51   1e-06
gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [...    45   1e-04
gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [...    45   1e-04
gi|238859557 regulatory factor X1 [Homo sapiens]                       42   9e-04
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  40   0.003
gi|32307177 forkhead box G1 [Homo sapiens]                             40   0.003
gi|112789555 ADAM metallopeptidase with thrombospondin type 1 mo...    40   0.003
gi|157743259 H6 family homeobox 3 [Homo sapiens]                       39   0.006
gi|40217801 hypothetical protein LOC79864 isoform 2 [Homo sapiens]     39   0.006
gi|18959210 WIRE protein [Homo sapiens]                                39   0.006
gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]     39   0.006
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    39   0.007
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    39   0.007
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    39   0.007
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    39   0.007
gi|19923350 nuclear factor of activated T-cells, cytosolic compo...    39   0.007
gi|27502393 nuclear factor of activated T-cells, cytosolic compo...    39   0.007
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    39   0.007
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]             39   0.010
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]        39   0.010
gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]        39   0.010
gi|14602439 Williams Beuren syndrome chromosome region 14 isofor...    38   0.013
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor...    38   0.013
gi|14602435 Williams Beuren syndrome chromosome region 14 isofor...    38   0.013
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor...    38   0.013
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  38   0.013
gi|226498192 atonal homolog 8 [Homo sapiens]                           38   0.017
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    38   0.017
gi|6912460 GRB2-associated binding protein 2 isoform b [Homo sap...    38   0.017

>gi|109452597 chromosome 10 open reading frame 46 [Homo sapiens]
          Length = 369

 Score =  747 bits (1928), Expect = 0.0
 Identities = 369/369 (100%), Positives = 369/369 (100%)

Query: 1   MEESMEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAV 60
           MEESMEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAV
Sbjct: 1   MEESMEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAV 60

Query: 61  PAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCDAAAAVAKAAPAPTASSTININTSTS 120
           PAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCDAAAAVAKAAPAPTASSTININTSTS
Sbjct: 61  PAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCDAAAAVAKAAPAPTASSTININTSTS 120

Query: 121 KFLMNVITIEDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMY 180
           KFLMNVITIEDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMY
Sbjct: 121 KFLMNVITIEDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMY 180

Query: 181 SDLIKKITNHLERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIETKL 240
           SDLIKKITNHLERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIETKL
Sbjct: 181 SDLIKKITNHLERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIETKL 240

Query: 241 NRDLKDDLIKLFTEHVAEKHIYSLMPLLLEAQSTPFQVTPSTMANIVKGLYTLRPEWVQM 300
           NRDLKDDLIKLFTEHVAEKHIYSLMPLLLEAQSTPFQVTPSTMANIVKGLYTLRPEWVQM
Sbjct: 241 NRDLKDDLIKLFTEHVAEKHIYSLMPLLLEAQSTPFQVTPSTMANIVKGLYTLRPEWVQM 300

Query: 301 APTLFSKFIPNILPPAVESELSEYAAQDQKFQRELIQNGFTRGDQSRKRAGDELAYNSSS 360
           APTLFSKFIPNILPPAVESELSEYAAQDQKFQRELIQNGFTRGDQSRKRAGDELAYNSSS
Sbjct: 301 APTLFSKFIPNILPPAVESELSEYAAQDQKFQRELIQNGFTRGDQSRKRAGDELAYNSSS 360

Query: 361 ACASSRGYR 369
           ACASSRGYR
Sbjct: 361 ACASSRGYR 369


>gi|4503165 cullin 3 [Homo sapiens]
          Length = 768

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 27/109 (24%), Positives = 59/109 (54%), Gaps = 4/109 (3%)

Query: 130 EDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMYSDLIKKITN 189
           E Y ++ W  L  AI ++  ++      +S+E++Y   Y  V  +H E++Y+ L + +T 
Sbjct: 27  EKYVNSIWDLLKNAIQEIQRKNNSG---LSFEELYRNAYTMVLHKHGEKLYTGLREVVTE 83

Query: 190 HL-ERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIE 237
           HL  +V +++  S  + +++  N A   +  A+  I  + +YM++ Y++
Sbjct: 84  HLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQ 132


>gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3
           [Homo sapiens]
          Length = 650

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/58 (46%), Positives = 27/58 (46%), Gaps = 18/58 (31%)

Query: 34  QPLPPPPPPSSIP-------APAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEA 84
           QP PPPPP S  P       AP R PPGG LL           P   L  GPQPPP A
Sbjct: 384 QPPPPPPPASQQPPPPPPPQAPVRLPPGGPLL-----------PSASLTRGPQPPPLA 430


>gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1
           [Homo sapiens]
          Length = 634

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/58 (46%), Positives = 27/58 (46%), Gaps = 18/58 (31%)

Query: 34  QPLPPPPPPSSIP-------APAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEA 84
           QP PPPPP S  P       AP R PPGG LL           P   L  GPQPPP A
Sbjct: 368 QPPPPPPPASQQPPPPPPPQAPVRLPPGGPLL-----------PSASLTRGPQPPPLA 414


>gi|238859557 regulatory factor X1 [Homo sapiens]
          Length = 979

 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 34/109 (31%), Positives = 46/109 (42%), Gaps = 36/109 (33%)

Query: 34  QPLPPPPPPSSIPAPAR-----------------------EPPGGQ------LLAVPAVS 64
           QP PPPPPP + P P +                       +PPGGQ      L AVPA S
Sbjct: 26  QPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQSPQPQAQPPGGQKQYVTELPAVPAPS 85

Query: 65  VDRKGPKEGLPMGPQPPPEANGVIMMLK-SCDAAAAVAKAAPAPTASST 112
                P       P P P+   V+ + + +  A+  V++A+P  TAS T
Sbjct: 86  QPTGAPT------PSPAPQQYIVVTVSEGAMRASETVSEASPGSTASQT 128


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 33/93 (35%), Positives = 38/93 (40%), Gaps = 24/93 (25%)

Query: 35   PLPPPPP------------------PSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPM 76
            P PPPPP                  PS  P+PAR+PP    LA P  +    G     P 
Sbjct: 1272 PKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAA--LAKPPGTPPSLGASPAKP- 1328

Query: 77   GPQPPPEANGVIMMLKSCDAAAAVAKAAPAPTA 109
               P P A  + +  K   AAAA A AA AP A
Sbjct: 1329 ---PSPGAPALHVPAKPPRAAAAAAAAAAAPPA 1358



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 31/81 (38%), Positives = 32/81 (39%), Gaps = 18/81 (22%)

Query: 31   GFRQPLPPPPPPSSIPAPAREPPG--GQLLAVPAVSVDRKGPKEGLPM--GPQPPPEANG 86
            G   P P P P    PA   +PPG    L A PA     K P  G P    P  PP A  
Sbjct: 1293 GSAGPSPAPSPARQPPAALAKPPGTPPSLGASPA-----KPPSPGAPALHVPAKPPRA-- 1345

Query: 87   VIMMLKSCDAAAAVAKAAPAP 107
                     AAAA A A PAP
Sbjct: 1346 -------AAAAAAAAAAPPAP 1359



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 18/48 (37%), Positives = 20/48 (41%), Gaps = 1/48 (2%)

Query: 37   PPPPPPSSIPAPAREP-PGGQLLAVPAVSVDRKGPKEGLPMGPQPPPE 83
            PP  PPS   +PA+ P PG   L VPA               P  PPE
Sbjct: 1314 PPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPE 1361



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 12/47 (25%)

Query: 36   LPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPP 82
            LPPPPPP+       EPP   L  +P +      P EG    P  PP
Sbjct: 1191 LPPPPPPA-------EPPPTDLAHLPPLP-----PPEGEARKPAKPP 1225


>gi|32307177 forkhead box G1 [Homo sapiens]
          Length = 489

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 26/55 (47%), Positives = 29/55 (52%), Gaps = 8/55 (14%)

Query: 35  PLPPPPP----PSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGL-PMGPQPPPEA 84
           P PPPPP    P   P PA +PP  Q    PA   D KGP++ L P  P PPP A
Sbjct: 63  PQPPPPPQQQQPPPPPPPAPQPP--QTRGAPAAD-DDKGPQQLLLPPPPPPPPAA 114



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 24/52 (46%), Positives = 28/52 (53%), Gaps = 8/52 (15%)

Query: 33  RQPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEA 84
           +Q  PPPPPP     PA +PP  Q    PA   D KGP++ L   P PPP A
Sbjct: 70  QQQQPPPPPP-----PAPQPP--QTRGAPAAD-DDKGPQQLLLPPPPPPPPA 113



 Score = 29.3 bits (64), Expect = 5.9
 Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

Query: 31  GFRQPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANG 86
           G +Q L PPPPP   P PA    G +   +        GP E  P+GP    +  G
Sbjct: 98  GPQQLLLPPPPP---PPPAAALDGAKADGLGGKGEPGGGPGELAPVGPDEKEKGAG 150


>gi|112789555 ADAM metallopeptidase with thrombospondin type 1
           motif, 19 preproprotein [Homo sapiens]
          Length = 1207

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 38/116 (32%), Positives = 45/116 (38%), Gaps = 29/116 (25%)

Query: 3   ESMEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQ-LLAVP 61
           ES E   G S  A +      +W+        P PP PPPS  PA   EP G + LL +P
Sbjct: 118 ESQELPRGSSGAAALSPGAPASWQP-------PPPPQPPPSPPPAQHAEPDGDEVLLRIP 170

Query: 62  AVSVD------RKG----PKEGLPMGPQPPPEANGVIMMLKSCDAAAAVAKAAPAP 107
           A S D      R G    P+  +   P P P   G           AA A   PAP
Sbjct: 171 AFSRDLYLLLRRDGRFLAPRFAVEQRPNPGPGPTG-----------AASAPQPPAP 215


>gi|157743259 H6 family homeobox 3 [Homo sapiens]
          Length = 357

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 32/84 (38%), Positives = 35/84 (41%), Gaps = 14/84 (16%)

Query: 26  EAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEAN 85
           +AA     QP PPPPPP   PAP   P   + L          G     P  PQPPP   
Sbjct: 7   DAAGTASAQPQPPPPPP---PAPKESPFSIKNLL--------NGDHHRPPPKPQPPPR-- 53

Query: 86  GVIMMLKSCDAAAAVAKAAPAPTA 109
             +    S  AAAA A AA A  A
Sbjct: 54  -TLFAPASAAAAAAAAAAAAAKGA 76


>gi|40217801 hypothetical protein LOC79864 isoform 2 [Homo sapiens]
          Length = 307

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 1/80 (1%)

Query: 5   MEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSI-PAPAREPPGGQLLAVPAV 63
           MEEE  G    M  +QNH+ W+   +  +QP+          P    +   GQLL+V A+
Sbjct: 88  MEEEASGKAAQMAREQNHHTWDQGANNRQQPIEDKYSDLRYDPNWKSKKEEGQLLSVEAL 147

Query: 64  SVDRKGPKEGLPMGPQPPPE 83
                   E LP+ P  P +
Sbjct: 148 PESTDSSLENLPLAPLYPSQ 167


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 10/75 (13%)

Query: 20  QNHNNWEAAVDGFRQPLPPPPPPSSIPA--------PAREPPGGQLLAVPAVSVDRKGPK 71
           Q HN+      G  + L PPPP S+ P+        PAR+PP       P   V R G +
Sbjct: 278 QRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGAR 337

Query: 72  EGLPMGPQPPPEANG 86
           +  P  P PP   +G
Sbjct: 338 DAPP--PPPPYRMHG 350



 Score = 33.1 bits (74), Expect = 0.41
 Identities = 20/47 (42%), Positives = 22/47 (46%), Gaps = 3/47 (6%)

Query: 35  PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPP 81
           P PPP  P   P   R  P GQ LA P     R+ P  G+P GP  P
Sbjct: 225 PAPPPVKPPPSPVNIRTGPSGQSLAPPPPPY-RQPP--GVPNGPSSP 268


>gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]
          Length = 778

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 1/80 (1%)

Query: 5   MEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSI-PAPAREPPGGQLLAVPAV 63
           MEEE  G    M  +QNH+ W+   +  +QP+          P    +   GQLL+V A+
Sbjct: 88  MEEEASGKAAQMAREQNHHTWDQGANNRQQPIEDKYSDLRYDPNWKSKKEEGQLLSVEAL 147

Query: 64  SVDRKGPKEGLPMGPQPPPE 83
                   E LP+ P  P +
Sbjct: 148 PESTDSSLENLPLAPLYPSQ 167


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 12/71 (16%)

Query: 35  PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSC 94
           P PPPPP +++ APA  PP   L   P V            + P PPP A  ++      
Sbjct: 353 PPPPPPPATALQAPAVPPPPAPLQIAPGV------------LHPAPPPIAPPLVQPSPPV 400

Query: 95  DAAAAVAKAAP 105
             AA V +  P
Sbjct: 401 ARAAPVCETVP 411



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 16/48 (33%), Positives = 18/48 (37%)

Query: 34  QPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPP 81
           Q LPPPPPP  +P P   P     +   A       P      GP  P
Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVP 468


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 12/71 (16%)

Query: 35  PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSC 94
           P PPPPP +++ APA  PP   L   P V            + P PPP A  ++      
Sbjct: 353 PPPPPPPATALQAPAVPPPPAPLQIAPGV------------LHPAPPPIAPPLVQPSPPV 400

Query: 95  DAAAAVAKAAP 105
             AA V +  P
Sbjct: 401 ARAAPVCETVP 411



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 16/48 (33%), Positives = 18/48 (37%)

Query: 34  QPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPP 81
           Q LPPPPPP  +P P   P     +   A       P      GP  P
Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVP 468


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 12/71 (16%)

Query: 35  PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSC 94
           P PPPPP +++ APA  PP   L   P V            + P PPP A  ++      
Sbjct: 353 PPPPPPPATALQAPAVPPPPAPLQIAPGV------------LHPAPPPIAPPLVQPSPPV 400

Query: 95  DAAAAVAKAAP 105
             AA V +  P
Sbjct: 401 ARAAPVCETVP 411



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 16/48 (33%), Positives = 18/48 (37%)

Query: 34  QPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPP 81
           Q LPPPPPP  +P P   P     +   A       P      GP  P
Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVP 468


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 12/71 (16%)

Query: 35  PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSC 94
           P PPPPP +++ APA  PP   L   P V            + P PPP A  ++      
Sbjct: 353 PPPPPPPATALQAPAVPPPPAPLQIAPGV------------LHPAPPPIAPPLVQPSPPV 400

Query: 95  DAAAAVAKAAP 105
             AA V +  P
Sbjct: 401 ARAAPVCETVP 411



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 16/48 (33%), Positives = 18/48 (37%)

Query: 34  QPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPP 81
           Q LPPPPPP  +P P   P     +   A       P      GP  P
Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVP 468


>gi|19923350 nuclear factor of activated T-cells, cytosolic
           component 1 isoform B [Homo sapiens]
          Length = 825

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 37/113 (32%), Positives = 51/113 (45%), Gaps = 30/113 (26%)

Query: 41  PPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCD----- 95
           P +S P P++ P G      PA +V  +G   G      P P A G    +KS +     
Sbjct: 2   PSTSFPVPSKFPLG------PAAAVFGRGETLG------PAPRAGGT---MKSAEEEHYG 46

Query: 96  -AAAAVAKAAPAPTASSTI-----NINTSTSKFLMNVITIEDYKSTYWPKLDG 142
            A++ V+ A P PTA ST+     N+ TST      +I   D+ S Y   LDG
Sbjct: 47  YASSNVSPALPLPTAHSTLPAPCHNLQTSTP----GIIPPADHPSGYGAALDG 95


>gi|27502393 nuclear factor of activated T-cells, cytosolic
           component 1 isoform A [Homo sapiens]
          Length = 716

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 37/113 (32%), Positives = 51/113 (45%), Gaps = 30/113 (26%)

Query: 41  PPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCD----- 95
           P +S P P++ P G      PA +V  +G   G      P P A G    +KS +     
Sbjct: 2   PSTSFPVPSKFPLG------PAAAVFGRGETLG------PAPRAGGT---MKSAEEEHYG 46

Query: 96  -AAAAVAKAAPAPTASSTI-----NINTSTSKFLMNVITIEDYKSTYWPKLDG 142
            A++ V+ A P PTA ST+     N+ TST      +I   D+ S Y   LDG
Sbjct: 47  YASSNVSPALPLPTAHSTLPAPCHNLQTSTP----GIIPPADHPSGYGAALDG 95


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 26/77 (33%), Positives = 29/77 (37%), Gaps = 5/77 (6%)

Query: 36  LPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMG-----PQPPPEANGVIMM 90
           LPPPPPP  +  P   PP    +  P   V    P      G     P PPP A     +
Sbjct: 554 LPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPV 613

Query: 91  LKSCDAAAAVAKAAPAP 107
             S     AVAK  P P
Sbjct: 614 PDSARPPPAVAKRPPVP 630



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 4/31 (12%)

Query: 27  AAVDGFRQPLPPPPPPSSIPAP----AREPP 53
           A + G   P PPPPPP+  PAP    AR PP
Sbjct: 591 AGIAGSELPPPPPPPPAPAPAPVPDSARPPP 621


>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
          Length = 502

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 12/53 (22%)

Query: 33  RQPLPPPPPPSSIPAPAREPPGGQLLAVPAV---SVDRKGPKEGLPMGPQPPP 82
           ++PLPPPPPPS          GG  L  P +   +  R GP   +P+G  PPP
Sbjct: 310 QEPLPPPPPPSR---------GGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPP 353



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 18/52 (34%), Positives = 22/52 (42%)

Query: 35  PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANG 86
           P  PPPP    P P   P  G+   +P       GP    P  P PPP ++G
Sbjct: 356 PRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSG 407



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 14/75 (18%)

Query: 6   EEEEGGSYEAMMDD--QNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAVPAV 63
           +E+E  ++ A++ +  Q  N  ++   G R+ LPPPP P++      E  GG    +P +
Sbjct: 130 DEDEAQAFRALVQEKIQKRNQRQS---GDRRQLPPPPTPAN-----EERRGG----LPPL 177

Query: 64  SVDRKGPKEGLPMGP 78
            +   G + G P+GP
Sbjct: 178 PLHPGGDQGGPPVGP 192



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 3/54 (5%)

Query: 35  PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVD---RKGPKEGLPMGPQPPPEAN 85
           P PPP PP+ +PA    P GG+   +  +       K P        QPPP+++
Sbjct: 410 PAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSS 463


>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
          Length = 755

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 11/79 (13%)

Query: 14  EAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQL---------LAVPAVS 64
           EA + D   +  ++A      PLPPPPPP    A + E  G +L         +A  A +
Sbjct: 46  EASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAA 105

Query: 65  VDRKGPKEGLPMGPQPPPE 83
             + GP+  LP  P  PPE
Sbjct: 106 APQGGPE--LPPSPASPPE 122


>gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]
          Length = 560

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 11/79 (13%)

Query: 14  EAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQL---------LAVPAVS 64
           EA + D   +  ++A      PLPPPPPP    A + E  G +L         +A  A +
Sbjct: 46  EASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAA 105

Query: 65  VDRKGPKEGLPMGPQPPPE 83
             + GP+  LP  P  PPE
Sbjct: 106 APQGGPE--LPPSPASPPE 122


>gi|14602439 Williams Beuren syndrome chromosome region 14 isoform
           delta [Homo sapiens]
          Length = 831

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%)

Query: 35  PLPPP----PPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMM 90
           PLP P    P P S+P+PA  P   +LL +   S    GP   +P G  P P   G    
Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPFPIELLPL-GYSEPAFGPCFSMPRGKPPAPSPRG---- 502

Query: 91  LKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQ 150
            K+     A A A+P  TA        S +  L  ++T    +    P L   +   L +
Sbjct: 503 QKASPPTLAPATASPPTTAG-------SNNPCLTQLLTAAKPEQALEPPL---VSSTLLR 552

Query: 151 SPG 153
           SPG
Sbjct: 553 SPG 555


>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
           gamma [Homo sapiens]
          Length = 850

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%)

Query: 35  PLPPP----PPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMM 90
           PLP P    P P S+P+PA  P   +LL +   S    GP   +P G  P P   G    
Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPFPIELLPL-GYSEPAFGPCFSMPRGKPPAPSPRG---- 502

Query: 91  LKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQ 150
            K+     A A A+P  TA        S +  L  ++T    +    P L   +   L +
Sbjct: 503 QKASPPTLAPATASPPTTAG-------SNNPCLTQLLTAAKPEQALEPPL---VSSTLLR 552

Query: 151 SPG 153
           SPG
Sbjct: 553 SPG 555


>gi|14602435 Williams Beuren syndrome chromosome region 14 isoform
           beta [Homo sapiens]
          Length = 833

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%)

Query: 35  PLPPP----PPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMM 90
           PLP P    P P S+P+PA  P   +LL +   S    GP   +P G  P P   G    
Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPFPIELLPL-GYSEPAFGPCFSMPRGKPPAPSPRG---- 502

Query: 91  LKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQ 150
            K+     A A A+P  TA        S +  L  ++T    +    P L   +   L +
Sbjct: 503 QKASPPTLAPATASPPTTAG-------SNNPCLTQLLTAAKPEQALEPPL---VSSTLLR 552

Query: 151 SPG 153
           SPG
Sbjct: 553 SPG 555


>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
           alpha [Homo sapiens]
          Length = 852

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%)

Query: 35  PLPPP----PPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMM 90
           PLP P    P P S+P+PA  P   +LL +   S    GP   +P G  P P   G    
Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPFPIELLPL-GYSEPAFGPCFSMPRGKPPAPSPRG---- 502

Query: 91  LKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQ 150
            K+     A A A+P  TA        S +  L  ++T    +    P L   +   L +
Sbjct: 503 QKASPPTLAPATASPPTTAG-------SNNPCLTQLLTAAKPEQALEPPL---VSSTLLR 552

Query: 151 SPG 153
           SPG
Sbjct: 553 SPG 555


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 19/48 (39%), Positives = 22/48 (45%)

Query: 35   PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPP 82
            P PPPPPP   PAP +    G +     VS   + P    P  P PPP
Sbjct: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP 2005



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 13/23 (56%), Positives = 13/23 (56%)

Query: 35   PLPPPPPPSSIPAPAREPPGGQL 57
            P PPPPPP   P P   PP  QL
Sbjct: 2002 PPPPPPPPPPPPPPPSAPPQVQL 2024



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 14/32 (43%), Positives = 15/32 (46%)

Query: 35   PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVD 66
            P PPPPPP   P P   PP         VS+D
Sbjct: 1998 PPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLD 2029



 Score = 30.0 bits (66), Expect = 3.5
 Identities = 11/19 (57%), Positives = 11/19 (57%)

Query: 35   PLPPPPPPSSIPAPAREPP 53
            P PPPPPP   P P   PP
Sbjct: 1995 PTPPPPPPPPPPPPPPPPP 2013



 Score = 29.3 bits (64), Expect = 5.9
 Identities = 11/19 (57%), Positives = 11/19 (57%)

Query: 35   PLPPPPPPSSIPAPAREPP 53
            P PPPPPP   P P   PP
Sbjct: 1997 PPPPPPPPPPPPPPPPPPP 2015


>gi|226498192 atonal homolog 8 [Homo sapiens]
          Length = 321

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 28/91 (30%), Positives = 32/91 (35%), Gaps = 22/91 (24%)

Query: 8   EEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQ----------- 56
           E GGS    + D     +     G   P PPPPPP   PAP  + PGG            
Sbjct: 95  ERGGSRAPEVSDARKRCFALGAVGPGLPTPPPPPP---PAPQSQAPGGPEAQPFREPGLR 151

Query: 57  ---LLAVPAVSVDRKGPKEGLPMGPQPPPEA 84
              LL  P        P    P  P  PPE+
Sbjct: 152 PRILLCAPPAR-----PAPSAPPAPPAPPES 177



 Score = 32.3 bits (72), Expect = 0.70
 Identities = 27/66 (40%), Positives = 28/66 (42%), Gaps = 17/66 (25%)

Query: 34  QPLPPPPPPSSIPAPAREPPGGQLLA-------VPAVSVDRK--------GPKEGLPMGP 78
           QP+P P P     APA  P GG   A        P VS  RK        GP  GLP  P
Sbjct: 68  QPVPVPVPVPVPVAPAVPPRGGTDTAGERGGSRAPEVSDARKRCFALGAVGP--GLPTPP 125

Query: 79  QPPPEA 84
            PPP A
Sbjct: 126 PPPPPA 131


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 8/53 (15%)

Query: 38  PPPPPSSIP--APAREPPGGQLLAVPAVSVDRKGP------KEGLPMGPQPPP 82
           PPPPPS  P  AP   PP    +AVP    +R  P          P GP PPP
Sbjct: 310 PPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPP 362



 Score = 32.3 bits (72), Expect = 0.70
 Identities = 21/59 (35%), Positives = 23/59 (38%), Gaps = 7/59 (11%)

Query: 26  EAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEA 84
           EA  +  R+  PPPPPPS    P   PP       P  S     P  G    P PP  A
Sbjct: 266 EAVKNELRRQAPPPPPPSRGGPPPPPPP-------PHNSGPPPPPARGRGAPPPPPSRA 317



 Score = 32.0 bits (71), Expect = 0.91
 Identities = 22/54 (40%), Positives = 25/54 (46%), Gaps = 13/54 (24%)

Query: 35  PLPP----PPPPSSIP--APAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPP 82
           P PP    PPPP ++P  AP+  PP       P  SV   GP    P  P PPP
Sbjct: 336 PPPPNRMYPPPPPALPSSAPSGPPP-------PPPSVLGVGPVAPPPPPPPPPP 382



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 11/21 (52%), Positives = 12/21 (57%)

Query: 35  PLPPPPPPSSIPAPAREPPGG 55
           P+ PPPPP   P P   PP G
Sbjct: 370 PVAPPPPPPPPPPPGPPPPPG 390


>gi|6912460 GRB2-associated binding protein 2 isoform b [Homo
           sapiens]
          Length = 638

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 37/151 (24%), Positives = 55/151 (36%), Gaps = 13/151 (8%)

Query: 19  DQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGP 78
           D+NHN    A  G     PPP PP   P+ A  P  G     P +S + +     +P   
Sbjct: 295 DKNHNAMTVATPGDSAIAPPPRPPK--PSQAETPRWGSPQQRPPISENSRSVAATIPRRN 352

Query: 79  QPPPEANGVIMMLKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKST--- 135
             P   N  +    SC+      +   +    S  +++     FL   + +    ST   
Sbjct: 353 TLPAMDNSRLHRASSCETYEYPQRGGES-AGRSAESMSDGVGSFLPGKMIVGRSDSTNSE 411

Query: 136 --YWPKLDGAIDQLLTQSPGD-----YIPIS 159
             Y P   G+   L  +  GD     YIP+S
Sbjct: 412 DNYVPMNPGSSTLLAMERAGDNSQSVYIPMS 442


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,537,988
Number of Sequences: 37866
Number of extensions: 947748
Number of successful extensions: 14491
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 213
Number of HSP's successfully gapped in prelim test: 497
Number of HSP's that attempted gapping in prelim test: 9375
Number of HSP's gapped (non-prelim): 3789
length of query: 369
length of database: 18,247,518
effective HSP length: 104
effective length of query: 265
effective length of database: 14,309,454
effective search space: 3792005310
effective search space used: 3792005310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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