BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|109452597 chromosome 10 open reading frame 46 [Homo sapiens] (369 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|109452597 chromosome 10 open reading frame 46 [Homo sapiens] 747 0.0 gi|4503165 cullin 3 [Homo sapiens] 51 1e-06 gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [... 45 1e-04 gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [... 45 1e-04 gi|238859557 regulatory factor X1 [Homo sapiens] 42 9e-04 gi|18079216 CASK interacting protein 1 [Homo sapiens] 40 0.003 gi|32307177 forkhead box G1 [Homo sapiens] 40 0.003 gi|112789555 ADAM metallopeptidase with thrombospondin type 1 mo... 40 0.003 gi|157743259 H6 family homeobox 3 [Homo sapiens] 39 0.006 gi|40217801 hypothetical protein LOC79864 isoform 2 [Homo sapiens] 39 0.006 gi|18959210 WIRE protein [Homo sapiens] 39 0.006 gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens] 39 0.006 gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 39 0.007 gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 39 0.007 gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 39 0.007 gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 39 0.007 gi|19923350 nuclear factor of activated T-cells, cytosolic compo... 39 0.007 gi|27502393 nuclear factor of activated T-cells, cytosolic compo... 39 0.007 gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 39 0.007 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 39 0.010 gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens] 39 0.010 gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens] 39 0.010 gi|14602439 Williams Beuren syndrome chromosome region 14 isofor... 38 0.013 gi|14602437 Williams Beuren syndrome chromosome region 14 isofor... 38 0.013 gi|14602435 Williams Beuren syndrome chromosome region 14 isofor... 38 0.013 gi|14602433 Williams Beuren syndrome chromosome region 14 isofor... 38 0.013 gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 38 0.013 gi|226498192 atonal homolog 8 [Homo sapiens] 38 0.017 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 38 0.017 gi|6912460 GRB2-associated binding protein 2 isoform b [Homo sap... 38 0.017 >gi|109452597 chromosome 10 open reading frame 46 [Homo sapiens] Length = 369 Score = 747 bits (1928), Expect = 0.0 Identities = 369/369 (100%), Positives = 369/369 (100%) Query: 1 MEESMEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAV 60 MEESMEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAV Sbjct: 1 MEESMEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAV 60 Query: 61 PAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCDAAAAVAKAAPAPTASSTININTSTS 120 PAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCDAAAAVAKAAPAPTASSTININTSTS Sbjct: 61 PAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCDAAAAVAKAAPAPTASSTININTSTS 120 Query: 121 KFLMNVITIEDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMY 180 KFLMNVITIEDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMY Sbjct: 121 KFLMNVITIEDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMY 180 Query: 181 SDLIKKITNHLERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIETKL 240 SDLIKKITNHLERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIETKL Sbjct: 181 SDLIKKITNHLERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIETKL 240 Query: 241 NRDLKDDLIKLFTEHVAEKHIYSLMPLLLEAQSTPFQVTPSTMANIVKGLYTLRPEWVQM 300 NRDLKDDLIKLFTEHVAEKHIYSLMPLLLEAQSTPFQVTPSTMANIVKGLYTLRPEWVQM Sbjct: 241 NRDLKDDLIKLFTEHVAEKHIYSLMPLLLEAQSTPFQVTPSTMANIVKGLYTLRPEWVQM 300 Query: 301 APTLFSKFIPNILPPAVESELSEYAAQDQKFQRELIQNGFTRGDQSRKRAGDELAYNSSS 360 APTLFSKFIPNILPPAVESELSEYAAQDQKFQRELIQNGFTRGDQSRKRAGDELAYNSSS Sbjct: 301 APTLFSKFIPNILPPAVESELSEYAAQDQKFQRELIQNGFTRGDQSRKRAGDELAYNSSS 360 Query: 361 ACASSRGYR 369 ACASSRGYR Sbjct: 361 ACASSRGYR 369 >gi|4503165 cullin 3 [Homo sapiens] Length = 768 Score = 51.2 bits (121), Expect = 1e-06 Identities = 27/109 (24%), Positives = 59/109 (54%), Gaps = 4/109 (3%) Query: 130 EDYKSTYWPKLDGAIDQLLTQSPGDYIPISYEQIYSCVYKCVCQQHSEQMYSDLIKKITN 189 E Y ++ W L AI ++ ++ +S+E++Y Y V +H E++Y+ L + +T Sbjct: 27 EKYVNSIWDLLKNAIQEIQRKNNSG---LSFEELYRNAYTMVLHKHGEKLYTGLREVVTE 83 Query: 190 HL-ERVSKELQASPPDLYIERFNIALGQYMGALQSIVPLFIYMNKFYIE 237 HL +V +++ S + +++ N A + A+ I + +YM++ Y++ Sbjct: 84 HLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQ 132 >gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [Homo sapiens] Length = 650 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/58 (46%), Positives = 27/58 (46%), Gaps = 18/58 (31%) Query: 34 QPLPPPPPPSSIP-------APAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEA 84 QP PPPPP S P AP R PPGG LL P L GPQPPP A Sbjct: 384 QPPPPPPPASQQPPPPPPPQAPVRLPPGGPLL-----------PSASLTRGPQPPPLA 430 >gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [Homo sapiens] Length = 634 Score = 45.1 bits (105), Expect = 1e-04 Identities = 27/58 (46%), Positives = 27/58 (46%), Gaps = 18/58 (31%) Query: 34 QPLPPPPPPSSIP-------APAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEA 84 QP PPPPP S P AP R PPGG LL P L GPQPPP A Sbjct: 368 QPPPPPPPASQQPPPPPPPQAPVRLPPGGPLL-----------PSASLTRGPQPPPLA 414 >gi|238859557 regulatory factor X1 [Homo sapiens] Length = 979 Score = 42.0 bits (97), Expect = 9e-04 Identities = 34/109 (31%), Positives = 46/109 (42%), Gaps = 36/109 (33%) Query: 34 QPLPPPPPPSSIPAPAR-----------------------EPPGGQ------LLAVPAVS 64 QP PPPPPP + P P + +PPGGQ L AVPA S Sbjct: 26 QPQPPPPPPPAAPQPPQPPTAAATPQPQYVTELQSPQPQAQPPGGQKQYVTELPAVPAPS 85 Query: 65 VDRKGPKEGLPMGPQPPPEANGVIMMLK-SCDAAAAVAKAAPAPTASST 112 P P P P+ V+ + + + A+ V++A+P TAS T Sbjct: 86 QPTGAPT------PSPAPQQYIVVTVSEGAMRASETVSEASPGSTASQT 128 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 40.4 bits (93), Expect = 0.003 Identities = 33/93 (35%), Positives = 38/93 (40%), Gaps = 24/93 (25%) Query: 35 PLPPPPP------------------PSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPM 76 P PPPPP PS P+PAR+PP LA P + G P Sbjct: 1272 PKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAA--LAKPPGTPPSLGASPAKP- 1328 Query: 77 GPQPPPEANGVIMMLKSCDAAAAVAKAAPAPTA 109 P P A + + K AAAA A AA AP A Sbjct: 1329 ---PSPGAPALHVPAKPPRAAAAAAAAAAAPPA 1358 Score = 33.9 bits (76), Expect = 0.24 Identities = 31/81 (38%), Positives = 32/81 (39%), Gaps = 18/81 (22%) Query: 31 GFRQPLPPPPPPSSIPAPAREPPG--GQLLAVPAVSVDRKGPKEGLPM--GPQPPPEANG 86 G P P P P PA +PPG L A PA K P G P P PP A Sbjct: 1293 GSAGPSPAPSPARQPPAALAKPPGTPPSLGASPA-----KPPSPGAPALHVPAKPPRA-- 1345 Query: 87 VIMMLKSCDAAAAVAKAAPAP 107 AAAA A A PAP Sbjct: 1346 -------AAAAAAAAAAPPAP 1359 Score = 30.4 bits (67), Expect = 2.6 Identities = 18/48 (37%), Positives = 20/48 (41%), Gaps = 1/48 (2%) Query: 37 PPPPPPSSIPAPAREP-PGGQLLAVPAVSVDRKGPKEGLPMGPQPPPE 83 PP PPS +PA+ P PG L VPA P PPE Sbjct: 1314 PPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPE 1361 Score = 29.6 bits (65), Expect = 4.5 Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 12/47 (25%) Query: 36 LPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPP 82 LPPPPPP+ EPP L +P + P EG P PP Sbjct: 1191 LPPPPPPA-------EPPPTDLAHLPPLP-----PPEGEARKPAKPP 1225 >gi|32307177 forkhead box G1 [Homo sapiens] Length = 489 Score = 40.0 bits (92), Expect = 0.003 Identities = 26/55 (47%), Positives = 29/55 (52%), Gaps = 8/55 (14%) Query: 35 PLPPPPP----PSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGL-PMGPQPPPEA 84 P PPPPP P P PA +PP Q PA D KGP++ L P P PPP A Sbjct: 63 PQPPPPPQQQQPPPPPPPAPQPP--QTRGAPAAD-DDKGPQQLLLPPPPPPPPAA 114 Score = 39.3 bits (90), Expect = 0.006 Identities = 24/52 (46%), Positives = 28/52 (53%), Gaps = 8/52 (15%) Query: 33 RQPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEA 84 +Q PPPPPP PA +PP Q PA D KGP++ L P PPP A Sbjct: 70 QQQQPPPPPP-----PAPQPP--QTRGAPAAD-DDKGPQQLLLPPPPPPPPA 113 Score = 29.3 bits (64), Expect = 5.9 Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 3/56 (5%) Query: 31 GFRQPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANG 86 G +Q L PPPPP P PA G + + GP E P+GP + G Sbjct: 98 GPQQLLLPPPPP---PPPAAALDGAKADGLGGKGEPGGGPGELAPVGPDEKEKGAG 150 >gi|112789555 ADAM metallopeptidase with thrombospondin type 1 motif, 19 preproprotein [Homo sapiens] Length = 1207 Score = 40.0 bits (92), Expect = 0.003 Identities = 38/116 (32%), Positives = 45/116 (38%), Gaps = 29/116 (25%) Query: 3 ESMEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQ-LLAVP 61 ES E G S A + +W+ P PP PPPS PA EP G + LL +P Sbjct: 118 ESQELPRGSSGAAALSPGAPASWQP-------PPPPQPPPSPPPAQHAEPDGDEVLLRIP 170 Query: 62 AVSVD------RKG----PKEGLPMGPQPPPEANGVIMMLKSCDAAAAVAKAAPAP 107 A S D R G P+ + P P P G AA A PAP Sbjct: 171 AFSRDLYLLLRRDGRFLAPRFAVEQRPNPGPGPTG-----------AASAPQPPAP 215 >gi|157743259 H6 family homeobox 3 [Homo sapiens] Length = 357 Score = 39.3 bits (90), Expect = 0.006 Identities = 32/84 (38%), Positives = 35/84 (41%), Gaps = 14/84 (16%) Query: 26 EAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEAN 85 +AA QP PPPPPP PAP P + L G P PQPPP Sbjct: 7 DAAGTASAQPQPPPPPP---PAPKESPFSIKNLL--------NGDHHRPPPKPQPPPR-- 53 Query: 86 GVIMMLKSCDAAAAVAKAAPAPTA 109 + S AAAA A AA A A Sbjct: 54 -TLFAPASAAAAAAAAAAAAAKGA 76 >gi|40217801 hypothetical protein LOC79864 isoform 2 [Homo sapiens] Length = 307 Score = 39.3 bits (90), Expect = 0.006 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 1/80 (1%) Query: 5 MEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSI-PAPAREPPGGQLLAVPAV 63 MEEE G M +QNH+ W+ + +QP+ P + GQLL+V A+ Sbjct: 88 MEEEASGKAAQMAREQNHHTWDQGANNRQQPIEDKYSDLRYDPNWKSKKEEGQLLSVEAL 147 Query: 64 SVDRKGPKEGLPMGPQPPPE 83 E LP+ P P + Sbjct: 148 PESTDSSLENLPLAPLYPSQ 167 >gi|18959210 WIRE protein [Homo sapiens] Length = 440 Score = 39.3 bits (90), Expect = 0.006 Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 10/75 (13%) Query: 20 QNHNNWEAAVDGFRQPLPPPPPPSSIPA--------PAREPPGGQLLAVPAVSVDRKGPK 71 Q HN+ G + L PPPP S+ P+ PAR+PP P V R G + Sbjct: 278 QRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGAR 337 Query: 72 EGLPMGPQPPPEANG 86 + P P PP +G Sbjct: 338 DAPP--PPPPYRMHG 350 Score = 33.1 bits (74), Expect = 0.41 Identities = 20/47 (42%), Positives = 22/47 (46%), Gaps = 3/47 (6%) Query: 35 PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPP 81 P PPP P P R P GQ LA P R+ P G+P GP P Sbjct: 225 PAPPPVKPPPSPVNIRTGPSGQSLAPPPPPY-RQPP--GVPNGPSSP 268 >gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens] Length = 778 Score = 39.3 bits (90), Expect = 0.006 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 1/80 (1%) Query: 5 MEEEEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSI-PAPAREPPGGQLLAVPAV 63 MEEE G M +QNH+ W+ + +QP+ P + GQLL+V A+ Sbjct: 88 MEEEASGKAAQMAREQNHHTWDQGANNRQQPIEDKYSDLRYDPNWKSKKEEGQLLSVEAL 147 Query: 64 SVDRKGPKEGLPMGPQPPPE 83 E LP+ P P + Sbjct: 148 PESTDSSLENLPLAPLYPSQ 167 >gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 38.9 bits (89), Expect = 0.007 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 12/71 (16%) Query: 35 PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSC 94 P PPPPP +++ APA PP L P V + P PPP A ++ Sbjct: 353 PPPPPPPATALQAPAVPPPPAPLQIAPGV------------LHPAPPPIAPPLVQPSPPV 400 Query: 95 DAAAAVAKAAP 105 AA V + P Sbjct: 401 ARAAPVCETVP 411 Score = 31.2 bits (69), Expect = 1.6 Identities = 16/48 (33%), Positives = 18/48 (37%) Query: 34 QPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPP 81 Q LPPPPPP +P P P + A P GP P Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVP 468 >gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 38.9 bits (89), Expect = 0.007 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 12/71 (16%) Query: 35 PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSC 94 P PPPPP +++ APA PP L P V + P PPP A ++ Sbjct: 353 PPPPPPPATALQAPAVPPPPAPLQIAPGV------------LHPAPPPIAPPLVQPSPPV 400 Query: 95 DAAAAVAKAAP 105 AA V + P Sbjct: 401 ARAAPVCETVP 411 Score = 31.2 bits (69), Expect = 1.6 Identities = 16/48 (33%), Positives = 18/48 (37%) Query: 34 QPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPP 81 Q LPPPPPP +P P P + A P GP P Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVP 468 >gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 38.9 bits (89), Expect = 0.007 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 12/71 (16%) Query: 35 PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSC 94 P PPPPP +++ APA PP L P V + P PPP A ++ Sbjct: 353 PPPPPPPATALQAPAVPPPPAPLQIAPGV------------LHPAPPPIAPPLVQPSPPV 400 Query: 95 DAAAAVAKAAP 105 AA V + P Sbjct: 401 ARAAPVCETVP 411 Score = 31.2 bits (69), Expect = 1.6 Identities = 16/48 (33%), Positives = 18/48 (37%) Query: 34 QPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPP 81 Q LPPPPPP +P P P + A P GP P Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVP 468 >gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo sapiens] Length = 559 Score = 38.9 bits (89), Expect = 0.007 Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 12/71 (16%) Query: 35 PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSC 94 P PPPPP +++ APA PP L P V + P PPP A ++ Sbjct: 353 PPPPPPPATALQAPAVPPPPAPLQIAPGV------------LHPAPPPIAPPLVQPSPPV 400 Query: 95 DAAAAVAKAAP 105 AA V + P Sbjct: 401 ARAAPVCETVP 411 Score = 31.2 bits (69), Expect = 1.6 Identities = 16/48 (33%), Positives = 18/48 (37%) Query: 34 QPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPP 81 Q LPPPPPP +P P P + A P GP P Sbjct: 421 QGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVP 468 >gi|19923350 nuclear factor of activated T-cells, cytosolic component 1 isoform B [Homo sapiens] Length = 825 Score = 38.9 bits (89), Expect = 0.007 Identities = 37/113 (32%), Positives = 51/113 (45%), Gaps = 30/113 (26%) Query: 41 PPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCD----- 95 P +S P P++ P G PA +V +G G P P A G +KS + Sbjct: 2 PSTSFPVPSKFPLG------PAAAVFGRGETLG------PAPRAGGT---MKSAEEEHYG 46 Query: 96 -AAAAVAKAAPAPTASSTI-----NINTSTSKFLMNVITIEDYKSTYWPKLDG 142 A++ V+ A P PTA ST+ N+ TST +I D+ S Y LDG Sbjct: 47 YASSNVSPALPLPTAHSTLPAPCHNLQTSTP----GIIPPADHPSGYGAALDG 95 >gi|27502393 nuclear factor of activated T-cells, cytosolic component 1 isoform A [Homo sapiens] Length = 716 Score = 38.9 bits (89), Expect = 0.007 Identities = 37/113 (32%), Positives = 51/113 (45%), Gaps = 30/113 (26%) Query: 41 PPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMMLKSCD----- 95 P +S P P++ P G PA +V +G G P P A G +KS + Sbjct: 2 PSTSFPVPSKFPLG------PAAAVFGRGETLG------PAPRAGGT---MKSAEEEHYG 46 Query: 96 -AAAAVAKAAPAPTASSTI-----NINTSTSKFLMNVITIEDYKSTYWPKLDG 142 A++ V+ A P PTA ST+ N+ TST +I D+ S Y LDG Sbjct: 47 YASSNVSPALPLPTAHSTLPAPCHNLQTSTP----GIIPPADHPSGYGAALDG 95 >gi|56118221 amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein [Homo sapiens] Length = 666 Score = 38.9 bits (89), Expect = 0.007 Identities = 26/77 (33%), Positives = 29/77 (37%), Gaps = 5/77 (6%) Query: 36 LPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMG-----PQPPPEANGVIMM 90 LPPPPPP + P PP + P V P G P PPP A + Sbjct: 554 LPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPV 613 Query: 91 LKSCDAAAAVAKAAPAP 107 S AVAK P P Sbjct: 614 PDSARPPPAVAKRPPVP 630 Score = 34.3 bits (77), Expect = 0.18 Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 4/31 (12%) Query: 27 AAVDGFRQPLPPPPPPSSIPAP----AREPP 53 A + G P PPPPPP+ PAP AR PP Sbjct: 591 AGIAGSELPPPPPPPPAPAPAPVPDSARPPP 621 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 38.5 bits (88), Expect = 0.010 Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 12/53 (22%) Query: 33 RQPLPPPPPPSSIPAPAREPPGGQLLAVPAV---SVDRKGPKEGLPMGPQPPP 82 ++PLPPPPPPS GG L P + + R GP +P+G PPP Sbjct: 310 QEPLPPPPPPSR---------GGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPP 353 Score = 34.3 bits (77), Expect = 0.18 Identities = 18/52 (34%), Positives = 22/52 (42%) Query: 35 PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANG 86 P PPPP P P P G+ +P GP P P PPP ++G Sbjct: 356 PRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSG 407 Score = 31.6 bits (70), Expect = 1.2 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 14/75 (18%) Query: 6 EEEEGGSYEAMMDD--QNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAVPAV 63 +E+E ++ A++ + Q N ++ G R+ LPPPP P++ E GG +P + Sbjct: 130 DEDEAQAFRALVQEKIQKRNQRQS---GDRRQLPPPPTPAN-----EERRGG----LPPL 177 Query: 64 SVDRKGPKEGLPMGP 78 + G + G P+GP Sbjct: 178 PLHPGGDQGGPPVGP 192 Score = 31.2 bits (69), Expect = 1.6 Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 3/54 (5%) Query: 35 PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVD---RKGPKEGLPMGPQPPPEAN 85 P PPP PP+ +PA P GG+ + + K P QPPP+++ Sbjct: 410 PAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSS 463 >gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens] Length = 755 Score = 38.5 bits (88), Expect = 0.010 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 11/79 (13%) Query: 14 EAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQL---------LAVPAVS 64 EA + D + ++A PLPPPPPP A + E G +L +A A + Sbjct: 46 EASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAA 105 Query: 65 VDRKGPKEGLPMGPQPPPE 83 + GP+ LP P PPE Sbjct: 106 APQGGPE--LPPSPASPPE 122 >gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens] Length = 560 Score = 38.5 bits (88), Expect = 0.010 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 11/79 (13%) Query: 14 EAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQL---------LAVPAVS 64 EA + D + ++A PLPPPPPP A + E G +L +A A + Sbjct: 46 EASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAA 105 Query: 65 VDRKGPKEGLPMGPQPPPE 83 + GP+ LP P PPE Sbjct: 106 APQGGPE--LPPSPASPPE 122 >gi|14602439 Williams Beuren syndrome chromosome region 14 isoform delta [Homo sapiens] Length = 831 Score = 38.1 bits (87), Expect = 0.013 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%) Query: 35 PLPPP----PPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMM 90 PLP P P P S+P+PA P +LL + S GP +P G P P G Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPFPIELLPL-GYSEPAFGPCFSMPRGKPPAPSPRG---- 502 Query: 91 LKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQ 150 K+ A A A+P TA S + L ++T + P L + L + Sbjct: 503 QKASPPTLAPATASPPTTAG-------SNNPCLTQLLTAAKPEQALEPPL---VSSTLLR 552 Query: 151 SPG 153 SPG Sbjct: 553 SPG 555 >gi|14602437 Williams Beuren syndrome chromosome region 14 isoform gamma [Homo sapiens] Length = 850 Score = 38.1 bits (87), Expect = 0.013 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%) Query: 35 PLPPP----PPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMM 90 PLP P P P S+P+PA P +LL + S GP +P G P P G Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPFPIELLPL-GYSEPAFGPCFSMPRGKPPAPSPRG---- 502 Query: 91 LKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQ 150 K+ A A A+P TA S + L ++T + P L + L + Sbjct: 503 QKASPPTLAPATASPPTTAG-------SNNPCLTQLLTAAKPEQALEPPL---VSSTLLR 552 Query: 151 SPG 153 SPG Sbjct: 553 SPG 555 >gi|14602435 Williams Beuren syndrome chromosome region 14 isoform beta [Homo sapiens] Length = 833 Score = 38.1 bits (87), Expect = 0.013 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%) Query: 35 PLPPP----PPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMM 90 PLP P P P S+P+PA P +LL + S GP +P G P P G Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPFPIELLPL-GYSEPAFGPCFSMPRGKPPAPSPRG---- 502 Query: 91 LKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQ 150 K+ A A A+P TA S + L ++T + P L + L + Sbjct: 503 QKASPPTLAPATASPPTTAG-------SNNPCLTQLLTAAKPEQALEPPL---VSSTLLR 552 Query: 151 SPG 153 SPG Sbjct: 553 SPG 555 >gi|14602433 Williams Beuren syndrome chromosome region 14 isoform alpha [Homo sapiens] Length = 852 Score = 38.1 bits (87), Expect = 0.013 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%) Query: 35 PLPPP----PPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEANGVIMM 90 PLP P P P S+P+PA P +LL + S GP +P G P P G Sbjct: 448 PLPAPAAFPPTPQSVPSPAPTPFPIELLPL-GYSEPAFGPCFSMPRGKPPAPSPRG---- 502 Query: 91 LKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKSTYWPKLDGAIDQLLTQ 150 K+ A A A+P TA S + L ++T + P L + L + Sbjct: 503 QKASPPTLAPATASPPTTAG-------SNNPCLTQLLTAAKPEQALEPPL---VSSTLLR 552 Query: 151 SPG 153 SPG Sbjct: 553 SPG 555 >gi|126090663 zinc finger homeodomain 4 [Homo sapiens] Length = 3571 Score = 38.1 bits (87), Expect = 0.013 Identities = 19/48 (39%), Positives = 22/48 (45%) Query: 35 PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPP 82 P PPPPPP PAP + G + VS + P P P PPP Sbjct: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP 2005 Score = 31.2 bits (69), Expect = 1.6 Identities = 13/23 (56%), Positives = 13/23 (56%) Query: 35 PLPPPPPPSSIPAPAREPPGGQL 57 P PPPPPP P P PP QL Sbjct: 2002 PPPPPPPPPPPPPPPSAPPQVQL 2024 Score = 30.4 bits (67), Expect = 2.6 Identities = 14/32 (43%), Positives = 15/32 (46%) Query: 35 PLPPPPPPSSIPAPAREPPGGQLLAVPAVSVD 66 P PPPPPP P P PP VS+D Sbjct: 1998 PPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLD 2029 Score = 30.0 bits (66), Expect = 3.5 Identities = 11/19 (57%), Positives = 11/19 (57%) Query: 35 PLPPPPPPSSIPAPAREPP 53 P PPPPPP P P PP Sbjct: 1995 PTPPPPPPPPPPPPPPPPP 2013 Score = 29.3 bits (64), Expect = 5.9 Identities = 11/19 (57%), Positives = 11/19 (57%) Query: 35 PLPPPPPPSSIPAPAREPP 53 P PPPPPP P P PP Sbjct: 1997 PPPPPPPPPPPPPPPPPPP 2015 >gi|226498192 atonal homolog 8 [Homo sapiens] Length = 321 Score = 37.7 bits (86), Expect = 0.017 Identities = 28/91 (30%), Positives = 32/91 (35%), Gaps = 22/91 (24%) Query: 8 EEGGSYEAMMDDQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQ----------- 56 E GGS + D + G P PPPPPP PAP + PGG Sbjct: 95 ERGGSRAPEVSDARKRCFALGAVGPGLPTPPPPPP---PAPQSQAPGGPEAQPFREPGLR 151 Query: 57 ---LLAVPAVSVDRKGPKEGLPMGPQPPPEA 84 LL P P P P PPE+ Sbjct: 152 PRILLCAPPAR-----PAPSAPPAPPAPPES 177 Score = 32.3 bits (72), Expect = 0.70 Identities = 27/66 (40%), Positives = 28/66 (42%), Gaps = 17/66 (25%) Query: 34 QPLPPPPPPSSIPAPAREPPGGQLLA-------VPAVSVDRK--------GPKEGLPMGP 78 QP+P P P APA P GG A P VS RK GP GLP P Sbjct: 68 QPVPVPVPVPVPVAPAVPPRGGTDTAGERGGSRAPEVSDARKRCFALGAVGP--GLPTPP 125 Query: 79 QPPPEA 84 PPP A Sbjct: 126 PPPPPA 131 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 37.7 bits (86), Expect = 0.017 Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 8/53 (15%) Query: 38 PPPPPSSIP--APAREPPGGQLLAVPAVSVDRKGP------KEGLPMGPQPPP 82 PPPPPS P AP PP +AVP +R P P GP PPP Sbjct: 310 PPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPP 362 Score = 32.3 bits (72), Expect = 0.70 Identities = 21/59 (35%), Positives = 23/59 (38%), Gaps = 7/59 (11%) Query: 26 EAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPPEA 84 EA + R+ PPPPPPS P PP P S P G P PP A Sbjct: 266 EAVKNELRRQAPPPPPPSRGGPPPPPPP-------PHNSGPPPPPARGRGAPPPPPSRA 317 Score = 32.0 bits (71), Expect = 0.91 Identities = 22/54 (40%), Positives = 25/54 (46%), Gaps = 13/54 (24%) Query: 35 PLPP----PPPPSSIP--APAREPPGGQLLAVPAVSVDRKGPKEGLPMGPQPPP 82 P PP PPPP ++P AP+ PP P SV GP P P PPP Sbjct: 336 PPPPNRMYPPPPPALPSSAPSGPPP-------PPPSVLGVGPVAPPPPPPPPPP 382 Score = 29.6 bits (65), Expect = 4.5 Identities = 11/21 (52%), Positives = 12/21 (57%) Query: 35 PLPPPPPPSSIPAPAREPPGG 55 P+ PPPPP P P PP G Sbjct: 370 PVAPPPPPPPPPPPGPPPPPG 390 >gi|6912460 GRB2-associated binding protein 2 isoform b [Homo sapiens] Length = 638 Score = 37.7 bits (86), Expect = 0.017 Identities = 37/151 (24%), Positives = 55/151 (36%), Gaps = 13/151 (8%) Query: 19 DQNHNNWEAAVDGFRQPLPPPPPPSSIPAPAREPPGGQLLAVPAVSVDRKGPKEGLPMGP 78 D+NHN A G PPP PP P+ A P G P +S + + +P Sbjct: 295 DKNHNAMTVATPGDSAIAPPPRPPK--PSQAETPRWGSPQQRPPISENSRSVAATIPRRN 352 Query: 79 QPPPEANGVIMMLKSCDAAAAVAKAAPAPTASSTININTSTSKFLMNVITIEDYKST--- 135 P N + SC+ + + S +++ FL + + ST Sbjct: 353 TLPAMDNSRLHRASSCETYEYPQRGGES-AGRSAESMSDGVGSFLPGKMIVGRSDSTNSE 411 Query: 136 --YWPKLDGAIDQLLTQSPGD-----YIPIS 159 Y P G+ L + GD YIP+S Sbjct: 412 DNYVPMNPGSSTLLAMERAGDNSQSVYIPMS 442 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,537,988 Number of Sequences: 37866 Number of extensions: 947748 Number of successful extensions: 14491 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 213 Number of HSP's successfully gapped in prelim test: 497 Number of HSP's that attempted gapping in prelim test: 9375 Number of HSP's gapped (non-prelim): 3789 length of query: 369 length of database: 18,247,518 effective HSP length: 104 effective length of query: 265 effective length of database: 14,309,454 effective search space: 3792005310 effective search space used: 3792005310 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.