Guide to the Human Genome
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Search of human proteins with 14249534

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14249534 hypothetical protein LOC84915 [Homo sapiens]
         (452 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14249534 hypothetical protein LOC84915 [Homo sapiens]              921   0.0  
gi|117306178 hypothetical protein LOC55731 [Homo sapiens]             164   2e-40
gi|117306174 hypothetical protein LOC55731 [Homo sapiens]             164   2e-40
gi|163965366 nascent polypeptide-associated complex alpha subuni...    58   2e-08
gi|160707881 formin 2 [Homo sapiens]                                   56   8e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    54   3e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    54   4e-07
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    54   4e-07
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...    54   4e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    53   5e-07
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    52   8e-07
gi|112421108 capicua homolog [Homo sapiens]                            52   8e-07
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             52   1e-06
gi|9945318 MAX binding protein [Homo sapiens]                          50   3e-06
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]                50   3e-06
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]                50   3e-06
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         50   3e-06
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    50   4e-06
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     50   5e-06
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     50   5e-06
gi|28872796 CCAAT/enhancer binding protein beta [Homo sapiens]         49   7e-06
gi|56549694 enabled homolog isoform a [Homo sapiens]                   49   1e-05
gi|39930375 enabled homolog isoform b [Homo sapiens]                   49   1e-05
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi...    49   1e-05
gi|210032580 SET domain containing 1B [Homo sapiens]                   49   1e-05
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                49   1e-05
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  48   2e-05
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         48   2e-05
gi|55750053 atrophin-1 [Homo sapiens]                                  47   4e-05
gi|55750041 atrophin-1 [Homo sapiens]                                  47   4e-05

>gi|14249534 hypothetical protein LOC84915 [Homo sapiens]
          Length = 452

 Score =  921 bits (2381), Expect = 0.0
 Identities = 452/452 (100%), Positives = 452/452 (100%)

Query: 1   MLACLQRTQNAPGQHLACPSKSLELRKCEAVASAMHSSRYPSPAELDAYAEKVANSPLSI 60
           MLACLQRTQNAPGQHLACPSKSLELRKCEAVASAMHSSRYPSPAELDAYAEKVANSPLSI
Sbjct: 1   MLACLQRTQNAPGQHLACPSKSLELRKCEAVASAMHSSRYPSPAELDAYAEKVANSPLSI 60

Query: 61  KIFPTNIRVPQHKHLSRTVNGYDTGGQRYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAG 120
           KIFPTNIRVPQHKHLSRTVNGYDTGGQRYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAG
Sbjct: 61  KIFPTNIRVPQHKHLSRTVNGYDTGGQRYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAG 120

Query: 121 PAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAAS 180
           PAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAAS
Sbjct: 121 PAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAAS 180

Query: 181 VIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFP 240
           VIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFP
Sbjct: 181 VIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFP 240

Query: 241 SMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPL 300
           SMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPL
Sbjct: 241 SMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPL 300

Query: 301 RAYSGSTVASKSPEACGGRAYERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDY 360
           RAYSGSTVASKSPEACGGRAYERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDY
Sbjct: 301 RAYSGSTVASKSPEACGGRAYERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDY 360

Query: 361 YNPAAAVVVTELGPGAARELAGPPADALSGLPSKSVCNTSVLSSSLQSLEYLINDIRPPC 420
           YNPAAAVVVTELGPGAARELAGPPADALSGLPSKSVCNTSVLSSSLQSLEYLINDIRPPC
Sbjct: 361 YNPAAAVVVTELGPGAARELAGPPADALSGLPSKSVCNTSVLSSSLQSLEYLINDIRPPC 420

Query: 421 IKEQMLGKGYETVAVPRLLDHQHAHIRLPVYR 452
           IKEQMLGKGYETVAVPRLLDHQHAHIRLPVYR
Sbjct: 421 IKEQMLGKGYETVAVPRLLDHQHAHIRLPVYR 452


>gi|117306178 hypothetical protein LOC55731 [Homo sapiens]
          Length = 562

 Score =  164 bits (415), Expect = 2e-40
 Identities = 173/580 (29%), Positives = 236/580 (40%), Gaps = 146/580 (25%)

Query: 1   MLACLQRTQNAPGQHLACPSKSLELRKCEAVASAMHSSRYPSPAELDAYAEKVANSPLSI 60
           MLACL    +   Q L+    +  L+K +     M ++ YP+PAELDAYA+KVAN+PL+I
Sbjct: 1   MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQK-MRTAHYPTPAELDAYAKKVANNPLTI 59

Query: 61  KIFPTNIRVPQHKHLSRTVNGYDTGGQRYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAG 120
           KIFP +++VPQ KH+ RTVNG DT  QRYSPYP   A   GLLAIVK             
Sbjct: 60  KIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKV------------ 107

Query: 121 PAKSVLKSAEGKRTKLSPAAV-QVGIAPYP--VPSTLG---------------------- 155
           PAKS+LK  +G R +L P A+    +APY    PSTL                       
Sbjct: 108 PAKSILKDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHA 167

Query: 156 ---PLAYPK---PPEAPAPPPGL----------PAAATAASVIPLP-------------- 185
               L +P+   PP+A + P  L          P A T   V P                
Sbjct: 168 PPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLL 227

Query: 186 --GRGLP---LPP-------------------SNLPSIHSLLYQLNQQCQ--APGAAPPA 219
             GR +P    PP                   S  P + S+++Q+NQ CQ  A  +    
Sbjct: 228 HGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSV 287

Query: 220 CQGMAIPHPSPAKHGPV--PSFPSMAYSAAAGLPDC-RKGTELGQGATQALTLAGAAK-- 274
           C+G  I +PSP     +   S     +S    +P C     E    AT AL  AG     
Sbjct: 288 CEGQ-IANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLP 346

Query: 275 ------PAGYADSGLDYLLWPQ----------KPPPPPPQP--------LRAYSGSTVAS 310
                 P GY  S L  + W Q                P P         R  +G     
Sbjct: 347 TGISRVPTGY-PSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVG 405

Query: 311 KSP----EACGGRAY------ERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDY 360
           K+P    E C  +++      E+ + SP   G+  P ++  G YF   WN++L TP SD 
Sbjct: 406 KAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDS 465

Query: 361 YNPAAAVVVTELGPGAAREL---AGPPADALSGLPSKSVCNTSVLSSSLQSLEYLINDIR 417
                  +    G      L   A P A   +G     V +    +S +Q+++YL  D +
Sbjct: 466 SGSQDLAMPFHGGQPTGAPLDCAAAPGAHYRAGTGGGPVASQ---NSLMQTVDYLSGDFQ 522

Query: 418 PPCIKEQ---MLGKGYETVA--VPRLLDHQHAHIRLPVYR 452
             C +EQ   ML K +       P   + +  HI+ P YR
Sbjct: 523 QACFREQSLAMLSKAHRAPGNRAPDPTESRSLHIQHPGYR 562


>gi|117306174 hypothetical protein LOC55731 [Homo sapiens]
          Length = 562

 Score =  164 bits (415), Expect = 2e-40
 Identities = 173/580 (29%), Positives = 236/580 (40%), Gaps = 146/580 (25%)

Query: 1   MLACLQRTQNAPGQHLACPSKSLELRKCEAVASAMHSSRYPSPAELDAYAEKVANSPLSI 60
           MLACL    +   Q L+    +  L+K +     M ++ YP+PAELDAYA+KVAN+PL+I
Sbjct: 1   MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQK-MRTAHYPTPAELDAYAKKVANNPLTI 59

Query: 61  KIFPTNIRVPQHKHLSRTVNGYDTGGQRYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAG 120
           KIFP +++VPQ KH+ RTVNG DT  QRYSPYP   A   GLLAIVK             
Sbjct: 60  KIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKV------------ 107

Query: 121 PAKSVLKSAEGKRTKLSPAAV-QVGIAPYP--VPSTLG---------------------- 155
           PAKS+LK  +G R +L P A+    +APY    PSTL                       
Sbjct: 108 PAKSILKDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHA 167

Query: 156 ---PLAYPK---PPEAPAPPPGL----------PAAATAASVIPLP-------------- 185
               L +P+   PP+A + P  L          P A T   V P                
Sbjct: 168 PPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLL 227

Query: 186 --GRGLP---LPP-------------------SNLPSIHSLLYQLNQQCQ--APGAAPPA 219
             GR +P    PP                   S  P + S+++Q+NQ CQ  A  +    
Sbjct: 228 HGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSV 287

Query: 220 CQGMAIPHPSPAKHGPV--PSFPSMAYSAAAGLPDC-RKGTELGQGATQALTLAGAAK-- 274
           C+G  I +PSP     +   S     +S    +P C     E    AT AL  AG     
Sbjct: 288 CEGQ-IANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLP 346

Query: 275 ------PAGYADSGLDYLLWPQ----------KPPPPPPQP--------LRAYSGSTVAS 310
                 P GY  S L  + W Q                P P         R  +G     
Sbjct: 347 TGISRVPTGY-PSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVG 405

Query: 311 KSP----EACGGRAY------ERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDY 360
           K+P    E C  +++      E+ + SP   G+  P ++  G YF   WN++L TP SD 
Sbjct: 406 KAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDS 465

Query: 361 YNPAAAVVVTELGPGAAREL---AGPPADALSGLPSKSVCNTSVLSSSLQSLEYLINDIR 417
                  +    G      L   A P A   +G     V +    +S +Q+++YL  D +
Sbjct: 466 SGSQDLAMPFHGGQPTGAPLDCAAAPGAHYRAGTGGGPVASQ---NSLMQTVDYLSGDFQ 522

Query: 418 PPCIKEQ---MLGKGYETVA--VPRLLDHQHAHIRLPVYR 452
             C +EQ   ML K +       P   + +  HI+ P YR
Sbjct: 523 QACFREQSLAMLSKAHRAPGNRAPDPTESRSLHIQHPGYR 562


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 90/400 (22%), Positives = 125/400 (31%), Gaps = 69/400 (17%)

Query: 19   PSKSLELRKCEAVASAMHSSRYPSPAELDAYAEKVANSPLSIKIFPTNIRVPQHKHLSRT 78
            P  SL  +  +   +  HS   PSP      +     SP  + + P     P   +L   
Sbjct: 837  PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL--- 893

Query: 79   VNGYDTGGQRYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSP 138
                        P+P+                   +T AP       + S+  K+ + +P
Sbjct: 894  ------------PFPKE----------------GPATPAPKQAPALSMTSSSPKKARATP 925

Query: 139  AAVQVGIAPYP----------VPSTLGPLAYPKPPEAPAPPPGLPAAATAASVIPLPGRG 188
            A   +  +P P           PS  G  A P P  AP PP   P +       P P +G
Sbjct: 926  APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP-KG 984

Query: 189  LPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGM----AIPHPSPAKHGPVPSFPSMAY 244
             P PP+  P                G A P+ +G     A+  PSP        FP  A 
Sbjct: 985  APTPPAATP-----------PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS 1033

Query: 245  SAAAGLPDCRKG----TELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQ-- 298
            +  A  P   KG    T L +GA         +   G A   L     P    PP P+  
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG 1093

Query: 299  ---PLRAYSGSTVASKSPEACGGRAYERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVT 355
               P    +    A+  P   GG A     G+P       P+    G     P      T
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS--PKGGLATPPPKGAPTT 1151

Query: 356  PTSDYYNPAAAVVVTELGPGAARELAGPPADALSGLPSKS 395
            P +   +P    + T    GA    A  P     GL + S
Sbjct: 1152 PAATPPSPKGG-LATPPPKGAPTTPAATPPSPKGGLATPS 1190



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 75/325 (23%), Positives = 103/325 (31%), Gaps = 48/325 (14%)

Query: 105  IVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGI---APYPVPSTLGP-LAYP 160
            I  A    S    PA P      +    +   SP AV       AP P    + P +  P
Sbjct: 1549 IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608

Query: 161  KPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSI--HSLLYQLNQQCQAPGAAPP 218
             P EAP PP   P +       P P +G P  P   PS    S     +  C+     P 
Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPAP-KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667

Query: 219  ACQGM---------------AIPHPSPAKHGPVPSFPSMAYSAAAGLPDC-----RKGTE 258
            A +G+                 P  +P    P    P    S+A   P C     + G++
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727

Query: 259  LGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGG 318
                      L    K +     G D    P+ P  PP             SK+      
Sbjct: 1728 GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPP------------ESKASTPLTA 1775

Query: 319  RAYERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDYYNPAAAVVVTE-----LG 373
             A+E+    P +  V    S  V    A   + V   P    + P++  +V E     L 
Sbjct: 1776 AAFEKVLPKPESASVSAAPSPPVSLPLAP--SPVPTLPPKQQFLPSSPGLVLESPSKPLA 1833

Query: 374  PGAARELAG--PPADALSGLPSKSV 396
            P    EL    PP     G+P +SV
Sbjct: 1834 PADEDELLPLIPPEPISGGVPFQSV 1858



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 60/234 (25%), Positives = 78/234 (33%), Gaps = 29/234 (12%)

Query: 101  GLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYP 160
            GL         ++  A P  P K  L +   K    +PAA          PS  G LA P
Sbjct: 1139 GLATPPPKGAPTTPAATPPSP-KGGLATPPPKGAPTTPAATP--------PSPKGGLATP 1189

Query: 161  KPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQ--CQAPGAAPP 218
             P  AP  P   P +       P P      P +  PS    L   + +     P A PP
Sbjct: 1190 SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249

Query: 219  ACQ-GMAIPHPSPAKHGPVPSFPSM-----------AYSAAAGLPDCRKGTELGQGATQA 266
            + + G A P P  A   P  + PS+           A + A   P   KG         A
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309

Query: 267  LTLAGAAKPAGYADSGLDYLLWPQK--PPPPPPQPLRAYSGSTVASKSPEACGG 318
             T   A  P+     G      P K  P PP   P       T+ + +P + GG
Sbjct: 1310 PTPPAATPPSPKGSPGTP----PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 50/213 (23%), Positives = 71/213 (33%), Gaps = 36/213 (16%)

Query: 140  AVQVGIAPYPVPSTLGPLAYPKPPEA--------PAPPPGLPAAATAASVIPLPGRGLPL 191
            AV    +P   P+T  P   P PP A        P  PP    A T  +V P   +G P 
Sbjct: 1290 AVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP-KGAPTPPAVTPPSPKGTPT 1348

Query: 192  PPSNLPSIH-SLLYQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPV----------PSFP 240
             P+  PS         +++   P AA P+ +G     P   K GP           P+  
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408

Query: 241  SMAYSAAAGLPDCRKG----------------TELGQGATQALTLAGAAKPAGYADSGLD 284
             ++   A   P  R+G                  L +    +    G A P+   D  L 
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP 1468

Query: 285  YLLWPQKPPPPPPQPLRAYSGSTVASKSPEACG 317
             +  P    PP P+ +   S    A  +P   G
Sbjct: 1469 AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501



 Score = 33.5 bits (75), Expect = 0.41
 Identities = 78/315 (24%), Positives = 103/315 (32%), Gaps = 68/315 (21%)

Query: 108  AAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPV----------PSTLGPL 157
            A +  S   APA P      +   K     PA   V +   P           PS+ G  
Sbjct: 1406 AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDP 1465

Query: 158  AYPK-PPEAPAPPPGLPAAATAAS------------------VIPLPGRGLPLPPSN--- 195
              P   P +P  PP     AT++S                  VIP   + +P  PS+   
Sbjct: 1466 TLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525

Query: 196  -LPSIHSLLYQLNQQCQAPGAA--PPACQGMAIPHPSPAKHGPVP-SFPSMAYSAAAGLP 251
             +    +LL +      AP  A  PPA   M +P P      P P   P+   S  A  P
Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPA---MTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582

Query: 252  DCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASK 311
                       A    T  GA  P          LL P  P    P P  A +   V   
Sbjct: 1583 P----------AVTPSTYKGAPSP--------KELLIP--PAVTSPSPKEAPTPPAVTPP 1622

Query: 312  SPEACGGRAYERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDYYNPAAAV-VVT 370
            SPE   G A     G+P +  V      T      +P +   VT       P A+  +  
Sbjct: 1623 SPEK--GPATPAPKGTPTSPPV------TPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674

Query: 371  ELGPGAARELAGPPA 385
            + GP A +E+   PA
Sbjct: 1675 KKGPTALKEVLVAPA 1689


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 54/186 (29%), Positives = 66/186 (35%), Gaps = 32/186 (17%)

Query: 146  APYPVPSTLGPLAYPKPPEAPA----PPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHS 201
            A  P P  L  +  P PP  P     PPP LP A       PLPG G+P PP  LP +  
Sbjct: 1094 AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGAGIP-PPPPLPRVGI 1151

Query: 202  LLYQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQ 261
                           PP   G  IP P P     +P  P +      G+P       +G 
Sbjct: 1152 -------------PPPPPLPGAGIPPPPPLPGAGIPPPPPL---PGVGIPPPPPLPGVGI 1195

Query: 262  GATQALTLAGAAKPAGYADSGLDYLLWPQKPPPP---PPQPLRAYSGSTVASK------- 311
                 L  AG   P      G+     P  PPP    PP PL   SG  +  +       
Sbjct: 1196 PPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLP 1255

Query: 312  SPEACG 317
            +P+ CG
Sbjct: 1256 TPQVCG 1261



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 52/165 (31%), Positives = 59/165 (35%), Gaps = 21/165 (12%)

Query: 138  PAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLP 197
            P     GI P P     G L  P  P A  PPP     A      PLPG G+PLPP  LP
Sbjct: 913  PPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPP-LP 971

Query: 198  SIHSLLYQLNQQCQAPGAA---PPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCR 254
                    +      PGA    PP   G  IP P P     +P  P +     AG+P   
Sbjct: 972  GA-----GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL---PGAGIPPPP 1023

Query: 255  KGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQP 299
                 G      L  AG   P     +G+         PPPPP P
Sbjct: 1024 PLPGAGIPPPPPLPGAGIPPPPPLPGAGI---------PPPPPLP 1059



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 53/176 (30%), Positives = 59/176 (33%), Gaps = 40/176 (22%)

Query: 131  GKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPA----PPPGLPAAATAASVIPLPG 186
            G    L P     GI P   P  L     P PP  P     PPP LP A       PLPG
Sbjct: 961  GAGIPLPPPLPGAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPG 1016

Query: 187  RGLPLPPSNLPSIHSLLYQLNQQCQAPGAA---PPACQGMAIPHPSPAKHGPVPSFPSMA 243
             G+P PP                   PGA    PP   G  IP P P     +P  P + 
Sbjct: 1017 AGIPPPP-----------------PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL- 1058

Query: 244  YSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQP 299
                AG+P        G      L  AG   P     +G+         PPPPP P
Sbjct: 1059 --PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---------PPPPPLP 1103



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 53/168 (31%), Positives = 56/168 (33%), Gaps = 40/168 (23%)

Query: 146  APYPVPSTLGPLAYPKPPEAPA----PPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHS 201
            A  P P  L     P PP  P     PPP LP A       PLPG G+P PP        
Sbjct: 1061 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGVGIPPPP-------- 1111

Query: 202  LLYQLNQQCQAPGAA---PPACQGMAIPHPSP---AKHGPVPSFPSMAYSAAAGLPDCRK 255
                       PGA    PP   G  IP P P   A   P P  P +       LP    
Sbjct: 1112 ---------PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP---- 1158

Query: 256  GTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKP----PPPPPQP 299
                G G      L GA  P      G+     P  P    PPPPP P
Sbjct: 1159 ----GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLP 1202



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 51/168 (30%), Positives = 65/168 (38%), Gaps = 23/168 (13%)

Query: 146  APYPVPSTLGPLAYPKPPEAPA----PPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHS 201
            A  P P  L  +  P PP  P     PPP LP A       PLPG G+P PP  LP +  
Sbjct: 1138 AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP-PLPGVGIP-PPPPLPGV-- 1193

Query: 202  LLYQLNQQCQAPGAA---PPACQGMAIPHPSPAKHGP-----VPSFPSMAYSAAAGLPDC 253
                +      PGA    PP   GM IP P+PA   P     +P  P +  S    LP  
Sbjct: 1194 ---GIPPPPPLPGAGIPPPPPLPGMGIP-PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQV 1249

Query: 254  RKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLR 301
               T       Q         P+G    G++     +K P  P +P++
Sbjct: 1250 GSST---LPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMK 1294



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 52/177 (29%), Positives = 61/177 (34%), Gaps = 41/177 (23%)

Query: 146  APYPVPSTLGPLAYPKPPEAPAPPPGLP--AAATAASVI------------------PLP 185
            +P P+P T    + P     P PPP LP     T  S                    PLP
Sbjct: 857  SPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP 916

Query: 186  GRGLPLPPSNLPSIHSLLYQLNQQCQAPGAA---PPACQGMAIPHPSPAKHGPVPSFPSM 242
            G G+P PP  LP    L          PGA    PP   G AIP P P     +P  P +
Sbjct: 917  GAGIP-PPPPLPGAGILPLP-----PLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPL 970

Query: 243  AYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQP 299
                 AG+P        G      L  AG   P     +G+         PPPPP P
Sbjct: 971  ---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---------PPPPPLP 1015


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 83/340 (24%), Positives = 118/340 (34%), Gaps = 58/340 (17%)

Query: 110  VSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPS--TLGPLAYPKPPEAPA 167
            VS+   A    PA  V K A      L P A     +P P P      PL  P P  +P+
Sbjct: 724  VSAPPPAQDPAPATPVAKGAG-----LGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPS 778

Query: 168  PPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAI-- 225
             P   P   +     P P R    PPS   S+     +       P  APP   G+ +  
Sbjct: 779  LPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQ 838

Query: 226  -------PHPSPAKHGPVPSFPSMAYSA---------AAGLPDCRKGTELGQGATQALTL 269
                   P  +PA   P P  P +   +         A  LP     + +   +  +  L
Sbjct: 839  NQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRL 898

Query: 270  AGAAKPAGY---------------ADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPE 314
              A  P+ +                   L  +  P  PPPPPP+  +  +    A   P+
Sbjct: 899  P-APTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPK 957

Query: 315  ACGGRAYERASGSPL-NCGVGLPTSFTVGQYFAAPWNSVLVTPTSDYYNPAAAVVVTELG 373
            A   R ++  SG  L N   G P         AAP  S  + P +   +PAA+V+V+   
Sbjct: 958  ALLERFHQVPSGIILQNKAGGAP---------AAPQTSTSLGPLT---SPAASVLVSGQA 1005

Query: 374  PG----AARELAGPPADALSGLPSKSVCNTSVLSSSLQSL 409
            P     A      P   A +GLP          +S+L +L
Sbjct: 1006 PSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTL 1045



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 63/272 (23%), Positives = 92/272 (33%), Gaps = 65/272 (23%)

Query: 99  YQGLLAIVKAAVSSSSTAAPAGPAKS--------------VLKSAEGKRTKLSPAAVQVG 144
           +Q  +++   ++ + S  APAGPA +              +L + +G     +PAA    
Sbjct: 555 FQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE 614

Query: 145 IAPY---------------PVPSTLGPLAYPKPPEAPAPPPGLPAAATAASVIPLPGRG- 188
            AP                P+P  L      +PP+AP P    P  AT     P PG   
Sbjct: 615 AAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQ--PSPGLAS 672

Query: 189 ------LPLPPSNLP-------SIHSLLYQLNQQ----CQAPGAAPPACQGMAIPHPSPA 231
                 L  PPS  P       S+   L Q   Q     + P  + PA   ++ P P+  
Sbjct: 673 SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPA-- 730

Query: 232 KHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADS---------- 281
              P P+ P    +  AGL      ++        +  A   K  G + S          
Sbjct: 731 -QDPAPATP---VAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLG 786

Query: 282 GLDYLLWPQKPPPPPPQPLRAYSGSTVASKSP 313
              +L  P    PP   P R  S S   S+ P
Sbjct: 787 DSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPP 818



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 2/79 (2%)

Query: 143 VGIAPYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAAS--VIPLPGRGLPLPPSNLPSIH 200
           + + P+  P  LG +     P     P G P  ATAA+  + P+   G P+   N P+  
Sbjct: 192 LSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQ 251

Query: 201 SLLYQLNQQCQAPGAAPPA 219
            L  Q+        AA P+
Sbjct: 252 LLAKQVPVSGYLASAAGPS 270


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 73/291 (25%), Positives = 102/291 (35%), Gaps = 33/291 (11%)

Query: 113 SSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGL 172
           S +A P   A   L +   +     PA+  +  +  P P    PLA P P + P  PP  
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQVPPSPPAS 744

Query: 173 PAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAK 232
           P  + +A+  P     L  PP  +P        ++   + P  APPA   +A P P  A 
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA---LATP-PLQAL 800

Query: 233 HGPVPSFPSMA-YSAAAGLPDCRKGT--------------ELGQGATQALTLAGAAKP-- 275
             P  SFP  A +S +A LP     T              ++      + TL    +P  
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860

Query: 276 ----AGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGG----RAYERASGS 327
                  +   L   L P  PPPP   P    SG  +A  S  A       R Y+  SG 
Sbjct: 861 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD--SGP 918

Query: 328 PLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDYYNPAAAVV-VTELGPGAA 377
                   P    +     A W+     P +    P A +      GPG+A
Sbjct: 919 EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 969



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 77/302 (25%), Positives = 107/302 (35%), Gaps = 44/302 (14%)

Query: 110  VSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPP--EAPA 167
            +S S+T  P  P    L +A   +   SP A  + ++P   P    P A   PP    P+
Sbjct: 747  MSPSATPPPRVPP---LLAAPPLQVPPSPPA-SLPMSPLAKPPPQAPPALATPPLQALPS 802

Query: 168  PPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPH 227
            PP   P  A  +    LP   L  PP   P +  L   L Q   +P A+P        P 
Sbjct: 803  PPASFPGQAPFSPSASLPMSPLATPPPQAPPV--LAAPLLQVPPSPPASPTLQAPRRPPT 860

Query: 228  PSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLL 287
            P P       S P +  + A G P            + + TL+G    AG++ S      
Sbjct: 861  PGP---DTSVSGPRLTLALAPGPPP-------PPSRSPSSTLSG-PDLAGHSSSATS--- 906

Query: 288  WPQKPPPPPPQPLRAY----SGSTVASKSPE----ACGGRAYERASGSPLNC----GVGL 335
                     P+ LR Y     G   AS  P+    AC   A+ R    PL      G  L
Sbjct: 907  --------TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL 958

Query: 336  PTSFTVGQYFAAPWNSVLVTPTSDYYNPAAAVVVTELGPGAA--RELAGPPADALSGLPS 393
            P     G   A    ++  T   +   PA   +     PG +  +  AG  A A S  P 
Sbjct: 959  PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPK 1018

Query: 394  KS 395
            ++
Sbjct: 1019 QA 1020



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 51/206 (24%), Positives = 74/206 (35%), Gaps = 41/206 (19%)

Query: 109 AVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQV--------------GIAPYPVPSTL 154
           A+SS ++ +P  P  S++      ++ L+P ++Q                +AP P+ +  
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550

Query: 155 GPLAYP--KPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQA 212
            PL  P  + P  PAP P           +  P   L  PP   PS  +         QA
Sbjct: 551 APLTTPHLETPPCPAPCP-----------LQAPPSPLTTPPPETPSSIA-----TPPPQA 594

Query: 213 PGA-APPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAG 271
           P A A P  QG+  P  SP    P  + P +A       P           A+  L+   
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP--------SPPASPPLSPLA 646

Query: 272 AAKPAGYADSGLDYLLWPQKPPPPPP 297
              P       +  L  P  PPP PP
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPP 672



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 73/287 (25%), Positives = 101/287 (35%), Gaps = 37/287 (12%)

Query: 117 APAGPAKSVLKSAEGKRTKLSPAAVQVGI--APYPVPSTLGPLAYPKPP-EAPAPPPGLP 173
           AP  P  S   S     +  +P A+ V +  AP+  P        P PP +AP  PP  P
Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP--------PSPPVQAPFSPPASP 683

Query: 174 AAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPP--ACQGMAIPHPSPA 231
             + +A+        L  PP  +P        ++     P  APP  A   + +P PSP 
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP-PSP- 741

Query: 232 KHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQ-------ALTLAGAAKPAGYADSGLD 284
                P+ P M+ SA    P  R    L     Q       +L ++  AKP   A   L 
Sbjct: 742 -----PASPPMSPSAT---PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793

Query: 285 YLLWPQKPPPPPPQPLRA-YSGSTVASKSPEACGGRAYERASGSPLNCGVGLPTSFTVGQ 343
                  P PP   P +A +S S     SP A           +PL   + +P S     
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASP 850

Query: 344 YFAAPWNSVLVTPTSDYYNPAAAVVVTELGPGAARELAGPPADALSG 390
              AP       P +    P   +    L PG     +  P+  LSG
Sbjct: 851 TLQAPRRPPTPGPDTSVSGPRLTLA---LAPGPPPPPSRSPSSTLSG 894



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 52/200 (26%), Positives = 73/200 (36%), Gaps = 23/200 (11%)

Query: 103 LAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYP-- 160
           + + + A S+       GP KSV  ++E   T+ SPAA +        PS  G L  P  
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR-------PSAGGGLQRPAS 239

Query: 161 KPPEAPAPPPGLPAAA--TAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPP 218
           +   + A P   PA +  +A      P       P  L ++        ++  AP   P 
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299

Query: 219 ACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGY 278
           +   +A P PS  K  PVP   + A    A LP           +    T    A P+  
Sbjct: 300 SSSPLATPSPSGTKARPVPPPDNAATPLPATLPP----------SPPLATPLPLAPPSPS 349

Query: 279 ADSGLDYLLWPQKPPPPPPQ 298
           A   L  L  P  P  PP Q
Sbjct: 350 APPSLQTL--PSPPATPPSQ 367



 Score = 29.6 bits (65), Expect = 5.9
 Identities = 42/163 (25%), Positives = 56/163 (34%), Gaps = 13/163 (7%)

Query: 151 PSTLGP-LAYPKPPEAPAPPPGLPAAAT----AASVI---PLPGRGLPLPPSNLPSI--- 199
           P+   P L  P+PP +P PPP +  AA     AA  +   PL  R   +  + +P     
Sbjct: 17  PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76

Query: 200 HSLLYQLNQQCQAPGAAPPAC-QGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTE 258
                      + P + PPA  +G   P       GPV S P  A       P  +KG  
Sbjct: 77  AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS-PGRASGTTRPGPLGQKGLR 135

Query: 259 LGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLR 301
           +    T A   A  A       +G         P  P P   R
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR 178



 Score = 29.6 bits (65), Expect = 5.9
 Identities = 82/318 (25%), Positives = 114/318 (35%), Gaps = 53/318 (16%)

Query: 29  EAVASAM-HSSRYPSPA-----ELDAYAEKVANSPLSIKIFPTNIRVPQHKHLSRTVNGY 82
           ++V+SA  HS+  PSPA           ++ A+  LS    P +         S   +G 
Sbjct: 207 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS---------SPARSGP 257

Query: 83  DTGGQRYSPYPQHTAGYQGLLAIVKAAVSSS-STAAPA-GP-AKSVLKSAEGKRTKLSPA 139
              G   +P        +GL A+    V+     AAPA GP + S L +     TK  P 
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV 317

Query: 140 AVQVGIAPYPVPSTLGP---------LAYPKP---------PEAPAPPPGLPAAATAASV 181
                 A  P+P+TL P         LA P P         P  PA PP     +     
Sbjct: 318 PPPDNAAT-PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376

Query: 182 IPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPS-PAKHGPVPSFP 240
           +  P     +PP  +P  HSL     Q   +P A        ++  P+  A H  +   P
Sbjct: 377 MQAPPSLQTIPPIQVP--HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434

Query: 241 SMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPP--- 297
                A+   P     T       QA     A+ P       L   L P   P   P   
Sbjct: 435 RQT-QASLTSPSRPASTPPDSPPLQAPLSLPASPP-------LQTSLSPAVSPLSSPLTI 486

Query: 298 QPLRAYSGSTVASKSPEA 315
            PL+A   S++AS SP+A
Sbjct: 487 HPLQAL--SSLASHSPQA 502


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 78/302 (25%), Positives = 109/302 (36%), Gaps = 44/302 (14%)

Query: 119 AGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLPAAATA 178
           + P K+ L S  G  TK +   V    AP PVP    P   P PP  P PPP  PA+  +
Sbjct: 193 SSPIKTPLVSPPGPLTKGNLPVV----AP-PVPCAPPP---PPPPPPPTPPPLPPASVLS 244

Query: 179 ASVI----------PLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHP 228
              +          P+P     LPP   P + +      Q  Q P A PP     A    
Sbjct: 245 DKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYA--SC 302

Query: 229 SPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLW 288
           SP    P P  P +  S+    P   K         +A      A PA  A  G    L 
Sbjct: 303 SPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKA---GAQALPAPPAPPGSQPFLQ 359

Query: 289 PQ----------KPPPPPPQPLRAYSGSTVASKSPEACGGRAYERASGSPLNCGVGLPTS 338
            +          K  PPP  P R+ + + ++SKS +A      ++  G   N  + +   
Sbjct: 360 KKRHGRPGAGGGKLNPPPAPPARSPT-TELSSKSQQATAWTPTQQPGGQLRNGSLHIIDD 418

Query: 339 FTVGQYFAAPWNSVLVTPTSDYYNPAAAVVVTEL------GPGAARELAGPPADALSGLP 392
           F     F    +SV   P  D Y P   +  +++      GP    E  G  +D + G  
Sbjct: 419 FESKFTF----HSVEDFPPPDEYKPCQKIYPSKIPRSRTPGPWLQAEAVGQSSDDIKGRN 474

Query: 393 SK 394
           S+
Sbjct: 475 SQ 476



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 46/159 (28%), Positives = 55/159 (34%), Gaps = 28/159 (17%)

Query: 160 PKPPEAPAPPPGLPAAATAASVI--PLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAP 217
           P PP  P PPP LP    ++S I  PL     PL   NLP +   +      C  P   P
Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPV-----PCAPPPPPP 228

Query: 218 PACQGMAIPHPSPAKHGPVPSFPSMAYS---AAAGLPDCRKGTELGQGATQALTLAGAAK 274
           P       P P+P    P       A     A   LP       L          A  A 
Sbjct: 229 P-------PPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPAS 281

Query: 275 PAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSP 313
           PA  A          Q+PP PPP PL  Y+  +  +  P
Sbjct: 282 PAQDA----------QEPPAPPP-PLPPYASCSPRASLP 309



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 40/152 (26%), Positives = 52/152 (34%), Gaps = 32/152 (21%)

Query: 163 PEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQG 222
           P + AP P LP    +  +IP      P  P           +L    +A GAA  A   
Sbjct: 126 PGSRAPSPRLPNKTISGPLIP------PASP-----------RLGNTSEAHGAARTAPPR 168

Query: 223 MAIPHPSPAKHGPVPS--FPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYAD 280
             +P P P    P P    P +  S+    P       L +G      L   A P   A 
Sbjct: 169 PNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKG-----NLPVVAPPVPCAP 223

Query: 281 SGLDYLLWPQKPPPPPPQPLRAYSGSTVASKS 312
                   P  PPPPPP P      S ++ K+
Sbjct: 224 --------PPPPPPPPPTPPPLPPASVLSDKA 247


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 55/167 (32%), Positives = 64/167 (38%), Gaps = 26/167 (15%)

Query: 151  PSTLGPLAYPKPPEAPAPPPGLPAAATA-ASVIPLPGRGLPLPPSNLPSIHSLLYQLN-- 207
            P  L P + P PP   A PP +   A A ASV+P P  G   PP +L     +    +  
Sbjct: 962  PPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPA-GSGAPPGSLGPSEQIGQAGSTA 1020

Query: 208  --QQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQ 265
              QQ Q  GA  P      +P P P  HGP P FP+         P    G   G G   
Sbjct: 1021 GPQQQQPAGAPQPGAVPPGVPPPGP--HGPSP-FPNQQTP-----PSMMPGAVPGSGHPG 1072

Query: 266  ALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKS 312
                      AG A  GL +      PPPPPP P     GS   S S
Sbjct: 1073 V---------AGNAPLGLPF---GMPPPPPPPAPSIIPFGSLADSIS 1107



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 41/138 (29%), Positives = 57/138 (41%), Gaps = 17/138 (12%)

Query: 208  QQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLP-DCRKGTELGQ-GATQ 265
            QQ Q P A PP  Q    P P     GP P+   +A + A+ +P     G   G  G ++
Sbjct: 957  QQQQPPPALPPGSQ----PIPPTGAAGP-PAVHGLAVAPASVVPAPAGSGAPPGSLGPSE 1011

Query: 266  ALTLAGAA------KPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGR 319
             +  AG+       +PAG    G    + P  PPP P  P    +  T  S  P A  G 
Sbjct: 1012 QIGQAGSTAGPQQQQPAGAPQPGA---VPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS 1068

Query: 320  AYERASG-SPLNCGVGLP 336
             +   +G +PL    G+P
Sbjct: 1069 GHPGVAGNAPLGLPFGMP 1086



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 55/227 (24%), Positives = 79/227 (34%), Gaps = 52/227 (22%)

Query: 104  AIVKAAVSSSSTAAPAGPAKSVLK--SAEGKRTKLSPAAVQVGIAP--YPVPSTLGPLAY 159
            ++V A   S +     GP++ + +  S  G + +    A Q G  P   P P   GP  +
Sbjct: 992  SVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPF 1051

Query: 160  PK---PPEA--------------------------PAPPPGLPAAATAASVIPLPGRGLP 190
            P    PP                            P PPP  P+     S+       LP
Sbjct: 1052 PNQQTPPSMMPGAVPGSGHPGVAGNAPLGLPFGMPPPPPPPAPSIIPFGSLADSISINLP 1111

Query: 191  LPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGL 250
             PP+     H L +       APG  PP    +++ +P    H  +P+  +M  S    L
Sbjct: 1112 APPNLHGHHHHLPF-------APGTLPPPNLPVSMANP---LHPNLPATTTMPSS----L 1157

Query: 251  PDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPP 297
            P    G  LG  A Q+  +  A +  G        L  P  P PP P
Sbjct: 1158 P---LGPGLGSAAAQSPAIVAAVQ--GNLLPSASPLPDPGTPLPPDP 1199



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 3/86 (3%)

Query: 101  GLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYP 160
            G L      VS ++   P  PA + + S+      L  AA Q       V   L P A P
Sbjct: 1128 GTLPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGSAAAQSPAIVAAVQGNLLPSASP 1187

Query: 161  KP-PEAPAPPPGLPAAATAASVIPLP 185
             P P  P PP   P A +  +V P+P
Sbjct: 1188 LPDPGTPLPPD--PTAPSPGTVTPVP 1211


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 54/186 (29%), Positives = 65/186 (34%), Gaps = 27/186 (14%)

Query: 116 AAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLPAA 175
           A PA PA  +    EG     +P      +A  P P+  GP A P  P A A   G P  
Sbjct: 117 AGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGP-AKPAGPAALAARAG-PGP 174

Query: 176 ATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMA--IPHPSPAKH 233
                  P PG G P  P    +++     LN    A  A      G A  +P P PA  
Sbjct: 175 GPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP 234

Query: 234 GPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPP 293
           G V   P    +AA   P              A +   A  PA  A +          PP
Sbjct: 235 GTVIQTPPFVGAAAPPAP-------------AAPSPPAAPAPAAPAAA----------PP 271

Query: 294 PPPPQP 299
           PPPP P
Sbjct: 272 PPPPAP 277



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 61/207 (29%), Positives = 76/207 (36%), Gaps = 32/207 (15%)

Query: 108 AAVSSSSTAAPA------GPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPK 161
           A ++S   AAPA      GPA  +          +      VG A  P P+   P A P 
Sbjct: 203 ALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPA 262

Query: 162 PPEA-PAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPAC 220
           P     APPP  PA AT A     P      PP+  P++             P AA    
Sbjct: 263 PAAPAAAPPPPPPAPATLARPPGHPAG----PPTAAPAV-----------PPPAAAQNGG 307

Query: 221 QGMAIPHPSPAKHGP--VPSFPSMAYSAAAGLPDCRKGT--ELGQGATQALTLAGAAKPA 276
              A P P+PA  GP  V   P    +AAA  P  +  +   + Q A  A     A+ PA
Sbjct: 308 SAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPA 367

Query: 277 GYADSGL------DYLLWPQKPPPPPP 297
             A S +        L  P   PPP P
Sbjct: 368 STAASMVIGPTMQGALPSPAAVPPPAP 394



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 61/199 (30%), Positives = 74/199 (37%), Gaps = 46/199 (23%)

Query: 137 SPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAP---PPGLPAA-ATAASVIPLP-----GR 187
           +PAA     AP P      P   P PP APA    PPG PA   TAA  +P P     G 
Sbjct: 251 APAAPSPPAAPAPAAPAAAP---PPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGG 307

Query: 188 GLPLPPSNLPSIHSLLYQLNQ-------QCQAPG-----------AAPPACQGMAIPHPS 229
                P+  P+         Q          APG           AAPPA Q +A   P+
Sbjct: 308 SAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPA 367

Query: 230 ---------PAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYAD 280
                    P   G +PS P+     A G P     T L +GA  A+T + +  P     
Sbjct: 368 STAASMVIGPTMQGALPS-PAAVPPPAPGTP-----TGLPKGAAGAVTQSLSRTPTA-TT 420

Query: 281 SGLDYLLWPQKPPPPPPQP 299
           SG+   L P    P  PQP
Sbjct: 421 SGIRATLTPTVLAPRLPQP 439



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 88/328 (26%), Positives = 111/328 (33%), Gaps = 59/328 (17%)

Query: 91  PYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPV 150
           P P+ +AG    +    AAV++    APAGPAK              PAA+     P P 
Sbjct: 128 PPPEGSAGSCAPVPAA-AAVAAGPEPAPAGPAKPA-----------GPAALAARAGPGP- 174

Query: 151 PSTLGPLAYPKPPEAPAPPPGLPAAAT-------------AASVIPLPGRG----LPLPP 193
               GP   P P   P  P G  AA T             AA  + L   G    LPLP 
Sbjct: 175 ----GPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK 230

Query: 194 SNLPS--IHSLLYQLNQQCQAPGA-APPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGL 250
              P   I +  +       AP A +PPA    A P  +P    P P+  +      AG 
Sbjct: 231 PAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP 290

Query: 251 PDCRKGTELGQGATQALTLAGAA---KPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGST 307
           P           A Q    AGAA    PA    +G+     P      P   ++A S   
Sbjct: 291 PTAAPAVP-PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKR 349

Query: 308 VASKSPEACGGRAYERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDYYNPAAAV 367
           V   +P A    A   ASG         P S              L +P +    P A  
Sbjct: 350 VVQAAPPAAQTLA---ASG---------PASTAASMVIGPTMQGALPSPAA--VPPPAPG 395

Query: 368 VVTELGPGAA----RELAGPPADALSGL 391
             T L  GAA    + L+  P    SG+
Sbjct: 396 TPTGLPKGAAGAVTQSLSRTPTATTSGI 423


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 58/208 (27%), Positives = 77/208 (37%), Gaps = 33/208 (15%)

Query: 140  AVQVGIAPYPVPSTLGPLAY-PKPPEAPAP----------PPGLPAAATAASVIPLPG-R 187
            A ++G  P P P      A+ P+PP+ P P           PGL    +     P PG  
Sbjct: 948  APRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVL 1007

Query: 188  GLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAA 247
            G P PP     +H+ LY        P   P      A+P PSP    P P  P +AY  A
Sbjct: 1008 GQPPPP-----LHTQLYP------GPAQDPLPAHSGALPFPSPGP--PQPPHPPLAYGPA 1054

Query: 248  AGL----PDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPP--PPPQPLR 301
                   P     T  G  +    T +    P+     G   +  P +PP   PPP   R
Sbjct: 1055 PSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPV--PPRPPAAEPPPCLRR 1112

Query: 302  AYSGSTVASKSPEACGGRAYERASGSPL 329
              + + + S SPE+  G       G PL
Sbjct: 1113 GAAAADLLSSSPESQHGGTQSPGGGQPL 1140



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 62/231 (26%), Positives = 77/231 (33%), Gaps = 51/231 (22%)

Query: 138  PAAVQVGIAPYPVPSTL----GPLAYPKPPEAPAPPP-GLPAAAT--AASVIPLPGR--- 187
            PA   V     P+PS       P   P PP  P PPP  LP   T  A +  P+P +   
Sbjct: 879  PATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHF 938

Query: 188  ------GLPLP-----PSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHP------SP 230
                  G P P     P   P  H          QA G  PP  Q + + HP      +P
Sbjct: 939  SSGIPAGFPAPRIGPQPQPHPQPH--------PSQAFGPQPPQ-QPLPLQHPHLFPPQAP 989

Query: 231  AKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQ 290
                P   +P        G P     T+L           G A+    A SG   L +P 
Sbjct: 990  GLLPPQSPYPYAPQPGVLGQPPPPLHTQL---------YPGPAQDPLPAHSGA--LPFPS 1038

Query: 291  KPPPPPPQPLRAYSGSTVASKSPEACGGRAYERASGSPLNCGVGLPTSFTV 341
              PP PP P  AY      + S    G +A       P + G   P+   V
Sbjct: 1039 PGPPQPPHPPLAYG----PAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLV 1085



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 42/165 (25%), Positives = 58/165 (35%), Gaps = 15/165 (9%)

Query: 147 PYPVPSTLGPLAYPKP---PEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLL 203
           P+ +P   GP  YP P   PE    P   P     +S  P  G G   P + LPS     
Sbjct: 810 PHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSS--PYVGVGPAPPVAGLPSAPPPQ 867

Query: 204 YQLNQQCQAPGAAPPACQGMAIPHPS--PAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQ 261
           +   +   A   A      +  P PS    +  P P+ P   +      P     T    
Sbjct: 868 FSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYT-YPA 926

Query: 262 GATQALTLA---GAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAY 303
           GA Q +       +  PAG+    +     PQ  P P P P +A+
Sbjct: 927 GAKQPIPAQHHFSSGIPAGFPAPRIG----PQPQPHPQPHPSQAF 967



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 34/144 (23%), Positives = 52/144 (36%), Gaps = 21/144 (14%)

Query: 99   YQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYP-VPSTLGPL 157
            Y+ ++  V+  +       P  P  S   S +    + S   V  G  P   + +T+  L
Sbjct: 1446 YEAVVRHVEQVLQRHGVPPPCKPLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKL 1505

Query: 158  AYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAP 217
            +   P    +P   LP  A        PG    LPP++LP          +    P ++P
Sbjct: 1506 SIRPPGGLESPVASLPGPAEP------PG----LPPASLP----------ESTPIPSSSP 1545

Query: 218  PACQGMAIPHPSPAKHGPVPSFPS 241
            P         P P +  PVP  PS
Sbjct: 1546 PPLSSPLPEAPQPKEEPPVPEAPS 1569


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 59/195 (30%), Positives = 77/195 (39%), Gaps = 37/195 (18%)

Query: 114  STAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLP 173
            ++  P+GPA      + G+   L+P   QVG++P P P          PP   A  PG P
Sbjct: 1043 TSLGPSGPAFVQPLLSAGQAPLLAPG--QVGVSPVPSPQL--------PPACAA--PGGP 1090

Query: 174  AAATAASVIPLPGRGLPL-PPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAK 232
                  S  P P    PL  PS  P   SL+Y +     A    PPA   +    P+PA 
Sbjct: 1091 VITAFYSGSPAPTSSAPLAQPSQAPP--SLVYTV-----ATSTTPPAATILPKGPPAPAT 1143

Query: 233  HGPVPSFP-------SMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDY 285
              P P+ P       SM YS  A      K       A Q +  A A+ P G  ++G   
Sbjct: 1144 ATPAPTSPFPSATAGSMTYSLVA-----PKAQRPSPKAPQKVKAAIASIPVGSFEAGAS- 1197

Query: 286  LLWPQKPPPPPPQPL 300
                 +P P P QPL
Sbjct: 1198 ----GRPGPAPRQPL 1208



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 70/273 (25%), Positives = 99/273 (36%), Gaps = 38/273 (13%)

Query: 93   PQHTAGYQGLLAIVKAAVSS-------SSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGI 145
            P  +AG   LLA  +  VS         + AAP GP  +   S     T  +P A     
Sbjct: 1055 PLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQA 1114

Query: 146  AP---YPVPSTLGPLA---YPKPPEAPA---PPPGLP-AAATAAS-----VIPLPGRGLP 190
             P   Y V ++  P A    PK P APA   P P  P  +ATA S     V P   R  P
Sbjct: 1115 PPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSP 1174

Query: 191  LPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIP---------------HPSPAKHGP 235
              P  + +  + +   + +  A G   PA +    P                P+P    P
Sbjct: 1175 KAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPP 1234

Query: 236  VP-SFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPP 294
            +P ++   A S+    P   + T      T A     ++        GL+    P  PP 
Sbjct: 1235 LPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPS 1294

Query: 295  PPPQPLRAYSGSTVASKSPEACGGRAYERASGS 327
            P P P  A  GS+ +S    A      + A+G+
Sbjct: 1295 PAPAPAVAPGGSSESSSGRAAGDTPERKEAAGT 1327



 Score = 37.4 bits (85), Expect = 0.028
 Identities = 90/348 (25%), Positives = 118/348 (33%), Gaps = 70/348 (20%)

Query: 85   GGQRYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVL--------KSAEGK---- 132
            GG     Y   T   Q  +A   A    +  AAP+GPA +           S  GK    
Sbjct: 820  GGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAA 879

Query: 133  --RTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPG---LPAAATAASV------ 181
               T   P    V  AP P   ++ P+  P P  +    PG   +P AA + SV      
Sbjct: 880  TAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAG 939

Query: 182  --IPLPGRGLPLPPSNLPSIHSLLYQLNQ-QCQAPGAAPPACQGMAIPHP-SPAKHGPVP 237
              +PL      +P  N     S + QL       P    P      +P P S  +   +P
Sbjct: 940  QPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLP 999

Query: 238  SFPSMAYSAAAG---LP------DCRKGTELGQGATQALTL-------AGAAKPAGYADS 281
            S   + Y  +AG   LP        + GT    G T ++ L       +G A       +
Sbjct: 1000 SSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSA 1059

Query: 282  GLDYLLWP-QKPPPPPPQPLRAYSGSTVASKSPEACGGRAYERASGSPLNCGVGLPTSFT 340
            G   LL P Q    P P P           + P AC       A G P      + T+F 
Sbjct: 1060 GQAPLLAPGQVGVSPVPSP-----------QLPPACA------APGGP------VITAFY 1096

Query: 341  VGQYFAAPWNSVLVTPTSDYYNPAAAVVVTELGPGAAREL-AGPPADA 387
             G    AP +S  +   S         V T   P AA  L  GPPA A
Sbjct: 1097 SGS--PAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPA 1142



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 35/119 (29%), Positives = 47/119 (39%), Gaps = 6/119 (5%)

Query: 121  PAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYP--KPPEAPAPPPGLPAAATA 178
            P+     + + +   + P+ V + +    V   +   A P  +PP A AP P  P   TA
Sbjct: 1485 PSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTA 1544

Query: 179  ASVIPLPG-RGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGM-AIPHPSPAKHGP 235
            A+  P P   G P P S  PS  S   Q       P  + P   G    P PSP   GP
Sbjct: 1545 AAPAPTPSPAGGPDPTS--PSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGP 1601



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 21/96 (21%)

Query: 211  QAPGAAPPACQGMAIPHPSPAKHG-PVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTL 269
            +AP   PP     A P P+P+  G P P+ PS     A   P      E G G       
Sbjct: 1532 EAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQP----- 1586

Query: 270  AGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSG 305
                   G+  +       PQ P PPPP P  A +G
Sbjct: 1587 -------GWEGA-------PQ-PSPPPPGPSTAATG 1607



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 37/150 (24%), Positives = 54/150 (36%), Gaps = 32/150 (21%)

Query: 30   AVASAMHSSRYPSPAELDAYAEKVANSPLSIKIFPTNIRVPQHKHLSRTVNGYDTGGQRY 89
            A A+A   +RY      D +  KV    L +KI     ++ Q    + T      G +  
Sbjct: 1487 AQATAAFQARYA-----DIFPSKVC---LQLKIREVRQKIMQ----AATPTEQPPGAEAP 1534

Query: 90   SPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYP 149
             P P  T            A + + T +PAG       S++    + +P        P P
Sbjct: 1535 LPVPPPTG----------TAAAPAPTPSPAGGPDPTSPSSDSGTAQAAP--------PLP 1576

Query: 150  VPSTLGP--LAYPKPPEAPAPPPGLPAAAT 177
             P   GP    +   P+   PPPG   AAT
Sbjct: 1577 PPPESGPGQPGWEGAPQPSPPPPGPSTAAT 1606


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 81/310 (26%), Positives = 113/310 (36%), Gaps = 50/310 (16%)

Query: 108  AAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPA 167
            AAV  S+   PA PA +V    E      SPAA        P P        P  P A  
Sbjct: 990  AAVRVSTPEEPASPAAAVPTPEE----PTSPAAA------VPTPEE------PTSPAAAV 1033

Query: 168  PPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPH 227
            PPP  P +  AA  +P P      P S   ++ +     +     P    P     A+P 
Sbjct: 1034 PPPEEPTSPAAA--VPTPEE----PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1087

Query: 228  P----SPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGL 283
            P    SPA   P P  P+   S AA +P      E    A    T    A PA    +  
Sbjct: 1088 PEEPTSPAAAVPTPEEPT---SPAAAVP---TPEEPASPAAAVPTPEEPASPAAAVPTPE 1141

Query: 284  DYLLWPQKPPPPPPQPLRAYSGSTVA-----SKSPEACGGRAYERASGSPLNCGVGLPTS 338
            +    P  P P  P P  + S +        S SP A      E AS + +   +  PTS
Sbjct: 1142 E----PAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTS 1197

Query: 339  FTVGQYFAAPWNSVLVTPTSDYYNPAAAVVVTELGPGAARELAGP-----PADALSGLPS 393
                   + P  + +V    ++ +PAA+V  +E     A  ++ P     PA A+  L  
Sbjct: 1198 PAA----SVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEE 1253

Query: 394  KSVCNTSVLS 403
             +    +VL+
Sbjct: 1254 PTSSAAAVLT 1263



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 50/192 (26%), Positives = 68/192 (35%), Gaps = 31/192 (16%)

Query: 118  PAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLPAAAT 177
            PA PA +V    E         A      P P  S    +A P P E+ +P   +P  A 
Sbjct: 1130 PASPAAAVPTPEE--------PAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAE 1181

Query: 178  AASVIPL---------PGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHP 228
            +AS   +         P   +P P + + ++       +     P +  PA    A+ +P
Sbjct: 1182 SASFAAVVATLEEPTSPAASVPTPAAMVATLEEF---TSPAASVPTSEEPASLAAAVSNP 1238

Query: 229  ----SPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLD 284
                SPA    VP+      SAAA L       EL   A    T    A PA  A S L+
Sbjct: 1239 EEPTSPA--AAVPTLEEPTSSAAAVLTP----EELSSPAASVPTPEEPASPAA-AVSNLE 1291

Query: 285  YLLWPQKPPPPP 296
                P    P P
Sbjct: 1292 EPASPAAAVPTP 1303


>gi|9945318 MAX binding protein [Homo sapiens]
          Length = 582

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 55/174 (31%), Positives = 71/174 (40%), Gaps = 27/174 (15%)

Query: 156 PLAYPKPPEAPAPPPGLPAAATAASVIPLP-----GRGLPLPPSNLPSIHSLLYQLNQQC 210
           PL+ P PP AP PP   PA  T   VIP+P      + LP PP  LP+    L    +Q 
Sbjct: 66  PLSPPAPPPAPPPPLATPAPLT---VIPIPVVTNSPQPLP-PPPPLPAAAQPLPLAPRQP 121

Query: 211 QAPGAAPPACQGMAIPHPSPAKHGP-VPSFPSMAYSAAAGLPDCRKGTELGQGATQALTL 269
              GA      G++I  P+P    P VP+   +   + A +P       L    T  LT+
Sbjct: 122 ALVGA-----PGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTI 176

Query: 270 AGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVAS----KSPEACGGR 319
           A           G+   L PQ+PPPP    L+      V S    K P   G R
Sbjct: 177 A--------PHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTR 222



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 31/122 (25%), Positives = 48/122 (39%), Gaps = 27/122 (22%)

Query: 132 KRTKLSPAAVQVGIAPYP--------VPSTLGPLAYPKPPEA---PAPPPGLPAAATAAS 180
           K T   P+     + P+P        +P    P+   +P +    PAPPP  P AA A +
Sbjct: 365 KSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPP--PPAAPAQT 422

Query: 181 VIPLP-------GRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAKH 233
           ++P P       G G  +      +  S++  +N   Q PG       G  I H +P+  
Sbjct: 423 LVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPG-------GKHIAHIAPSAP 475

Query: 234 GP 235
            P
Sbjct: 476 SP 477



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 36/137 (26%), Positives = 53/137 (38%), Gaps = 26/137 (18%)

Query: 113 SSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGL 172
           +ST+  +    ++ +  E  R  L P  +     P  + STL     P P   PAP P  
Sbjct: 327 ASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTL-----PPPSTTPAPLPPH 381

Query: 173 PAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAK 232
           P         P P   + LPP++LP     + Q   Q + P  APP       P P+   
Sbjct: 382 PH--------PHP-HSVALPPAHLP-----VQQQQPQQKTPLPAPP-------PPPAAPA 420

Query: 233 HGPVPSFPSMAYSAAAG 249
              VP+   +  +A  G
Sbjct: 421 QTLVPAPAHLVATAGGG 437


>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
          Length = 1240

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 55/221 (24%), Positives = 87/221 (39%), Gaps = 26/221 (11%)

Query: 29  EAVASAMHSSRYPSPAELDAYAEKVANSPLSIKIFPT-NIRVPQHKHLSRTVNGYDTGGQ 87
           EA+ S ++ +   +    +   E+V    LS+K  P  +  V  HK +   ++    G  
Sbjct: 313 EALESLVNRAVLLASDAQECTLEEVVERLLSVKGRPRPSPLVKAHKSVQANLDQSQRGSS 372

Query: 88  RYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAP 147
                PQ+T   +  +   + A +++        ++S+LK ++ +  +      Q    P
Sbjct: 373 -----PQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQ-----QASTPP 422

Query: 148 YPVPSTLGPLAYPKPPEAPAPPP----GLPAAATAASVIPLPGRGLPLPPSNLPSIHSLL 203
            P P  L P +  +PP  P PPP    G  A  TA    PLPG G   PP+       L 
Sbjct: 423 PPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPA-----PPLP 477

Query: 204 YQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAY 244
             L   C+     PP   G+  P P P      P  P M +
Sbjct: 478 PPLPGSCEFLPPPPPPLPGLGCPPPPP------PLLPGMGW 512



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 29/97 (29%), Positives = 34/97 (35%), Gaps = 21/97 (21%)

Query: 113 SSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPP--------- 163
           SS   P  P    L S   K    +P        P P+P  LG +A P PP         
Sbjct: 433 SSAEPPPPPPPPPLPSVGAKALPTAPP-------PPPLPG-LGAMAPPAPPLPPPLPGSC 484

Query: 164 ----EAPAPPPGLPAAATAASVIPLPGRGLPLPPSNL 196
                 P P PGL        ++P  G G P PP  L
Sbjct: 485 EFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPL 521



 Score = 29.6 bits (65), Expect = 5.9
 Identities = 32/103 (31%), Positives = 36/103 (34%), Gaps = 18/103 (17%)

Query: 206 LNQQCQAPGAAPPA--CQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGA 263
           L QQ   P   PP     G +   P P    P+PS  + A   A   P        G GA
Sbjct: 414 LEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLP-----GLGA 468

Query: 264 TQALTLAGAAKPAGYADSGLDYLLWPQKPP------PPPPQPL 300
                +A  A P      G    L P  PP      PPPP PL
Sbjct: 469 -----MAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPL 506


>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
          Length = 1249

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 55/221 (24%), Positives = 87/221 (39%), Gaps = 26/221 (11%)

Query: 29  EAVASAMHSSRYPSPAELDAYAEKVANSPLSIKIFPT-NIRVPQHKHLSRTVNGYDTGGQ 87
           EA+ S ++ +   +    +   E+V    LS+K  P  +  V  HK +   ++    G  
Sbjct: 313 EALESLVNRAVLLASDAQECTLEEVVERLLSVKGRPRPSPLVKAHKSVQANLDQSQRGSS 372

Query: 88  RYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAP 147
                PQ+T   +  +   + A +++        ++S+LK ++ +  +      Q    P
Sbjct: 373 -----PQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQ-----QASTPP 422

Query: 148 YPVPSTLGPLAYPKPPEAPAPPP----GLPAAATAASVIPLPGRGLPLPPSNLPSIHSLL 203
            P P  L P +  +PP  P PPP    G  A  TA    PLPG G   PP+       L 
Sbjct: 423 PPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPA-----PPLP 477

Query: 204 YQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAY 244
             L   C+     PP   G+  P P P      P  P M +
Sbjct: 478 PPLPGSCEFLPPPPPPLPGLGCPPPPP------PLLPGMGW 512



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 29/97 (29%), Positives = 34/97 (35%), Gaps = 21/97 (21%)

Query: 113 SSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPP--------- 163
           SS   P  P    L S   K    +P        P P+P  LG +A P PP         
Sbjct: 433 SSAEPPPPPPPPPLPSVGAKALPTAPP-------PPPLPG-LGAMAPPAPPLPPPLPGSC 484

Query: 164 ----EAPAPPPGLPAAATAASVIPLPGRGLPLPPSNL 196
                 P P PGL        ++P  G G P PP  L
Sbjct: 485 EFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPL 521



 Score = 29.6 bits (65), Expect = 5.9
 Identities = 32/103 (31%), Positives = 36/103 (34%), Gaps = 18/103 (17%)

Query: 206 LNQQCQAPGAAPPA--CQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGA 263
           L QQ   P   PP     G +   P P    P+PS  + A   A   P        G GA
Sbjct: 414 LEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLP-----GLGA 468

Query: 264 TQALTLAGAAKPAGYADSGLDYLLWPQKPP------PPPPQPL 300
                +A  A P      G    L P  PP      PPPP PL
Sbjct: 469 -----MAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPL 506


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 84/318 (26%), Positives = 114/318 (35%), Gaps = 48/318 (15%)

Query: 90   SPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPA-----AVQVG 144
            +P   H  G    +A   + V   ++A  A P  S    A  + + L+PA     A+   
Sbjct: 1528 APTSSHVPGLNSTVAPACSPVLVPASAL-ASPFPSAPNPAPAQASLLAPASSASQALATP 1586

Query: 145  IAPYPVPSTLGPLAYPKPPEAP----APPPGLPAAATAASVIPLPGRGLPLPPSNLPSIH 200
            +AP   P T      P PP AP    AP PG  A   A+S  P+P     + PS+ P   
Sbjct: 1587 LAPMAAPQTAILAPSPAPPLAPLPVLAPSPG-AAPVLASSQTPVP----VMAPSSTPGT- 1640

Query: 201  SLLYQLNQQCQAPGAAPPACQGM-----AIPHPSPAKHGPVPSFPSMAYSAAAGLP---- 251
            SL          P  AP + Q M       P PSPA    +   P++A +     P    
Sbjct: 1641 SLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTL 1700

Query: 252  DCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASK 311
                G   G   TQ L+L  A   +    +    L     PP  P Q L       +A  
Sbjct: 1701 SLGTGNPQGPFPTQTLSLTPA---SSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPA 1757

Query: 312  SPEACGGRAYERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDYYNPAAAVVVTE 371
            SP                   VG   + T+     A  ++ L+ P S      +   V  
Sbjct: 1758 SP-------------------VGPAPAHTL-TLAPASSSASLLAPASVQTLTLSPAPVPT 1797

Query: 372  LGPGAARELAGPPADALS 389
            LGP AA+ LA  PA   S
Sbjct: 1798 LGPAAAQTLALAPASTQS 1815



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 75/286 (26%), Positives = 106/286 (37%), Gaps = 47/286 (16%)

Query: 147  PYPVPSTLGPLAYPKPPEAPAPPPGLPAAAT-AASVIPL-------------PGRGLPLP 192
            P  + S   PLA P  P AP PP   P+ A+ +AS + L             PG  L L 
Sbjct: 1470 PALLTSVTPPLA-PVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLA 1528

Query: 193  P--SNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGL 250
            P  S++P ++S +        AP  +P      A+  P P+   P P+  S+   A++  
Sbjct: 1529 PTSSHVPGLNSTV--------APACSPVLVPASALASPFPSAPNPAPAQASLLAPASSA- 1579

Query: 251  PDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLL-WPQKPPPPPPQPLRAYSGSTVA 309
                      Q     L    A + A  A S    L   P   P P   P+ A S + V 
Sbjct: 1580 ---------SQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVP 1630

Query: 310  SKSPEACGGRAYERASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDYYNPAAAVVV 369
              +P +  G +   AS  P    V  P+S        AP  S L +P S      A  + 
Sbjct: 1631 VMAPSSTPGTSLASASPVPAPTPVLAPSS--TQTMLPAPVPSPLPSPASTQTLALAPALA 1688

Query: 370  TELGPGAAREL--------AGP-PADALSGLPSKSVCNTSVLSSSL 406
              LG  +  +          GP P   LS  P+ S+  T   + SL
Sbjct: 1689 PTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSL 1734



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 52/193 (26%), Positives = 74/193 (38%), Gaps = 18/193 (9%)

Query: 112  SSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAY----PKPPEAPA 167
            S  T  P GP  +   S     + +   A  + +AP P    LGP       P PP APA
Sbjct: 1701 SLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGP---PLGPTQTLSLAPAPPLAPA 1757

Query: 168  PPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPH 227
             P G PA A   ++ P       L P+++ ++             P   P A Q +A+  
Sbjct: 1758 SPVG-PAPAHTLTLAPASSSASLLAPASVQTLTL------SPAPVPTLGPAAAQTLALAP 1810

Query: 228  PSPAKHGPVPSFPSMAYSAAAGLPDCRKGT-ELGQGATQALTL-AGAAKPAGYADSGLDY 285
             S        S   ++ S AA LP        + +     LTL +G   P   A S    
Sbjct: 1811 ASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGP 1870

Query: 286  LLWPQKPPPPPPQ 298
               P++ PPPPP+
Sbjct: 1871 R--PRRQPPPPPR 1881



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 3/98 (3%)

Query: 147  PYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQL 206
            P P P++  P A P     P   P   +A    +++P+     P PPS +P   S     
Sbjct: 2443 PRPTPAS-APAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTP 2501

Query: 207  NQQCQAPGA-APPACQGMAIPHPSPAKHGPVPSFPSMA 243
               C  P A  PP  Q   +   SP   GP PS P  A
Sbjct: 2502 PPACTPPPAHTPPPAQTCLVTPSSPLLLGP-PSVPISA 2538



 Score = 36.2 bits (82), Expect = 0.063
 Identities = 28/96 (29%), Positives = 39/96 (40%), Gaps = 15/96 (15%)

Query: 90   SPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKR------------TKLS 137
            SP P  T G      +   A++ +ST +PA  A S++ SA G              +K  
Sbjct: 1791 SPAPVPTLGPAAAQTL---ALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDE 1847

Query: 138  PAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLP 173
            P  + +   P   PST      P+P   P PPP  P
Sbjct: 1848 PDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSP 1883



 Score = 35.8 bits (81), Expect = 0.082
 Identities = 99/397 (24%), Positives = 137/397 (34%), Gaps = 104/397 (26%)

Query: 103  LAIVKAAVSSSSTAAPAGPAKSV--LKSAEGKRTKLS-PAAVQV--GIAPYPVPSTLG-- 155
            L +  A V   +   P    ++V  L SA G+   +S PA V +   +AP P P+ +   
Sbjct: 1216 LTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVL 1275

Query: 156  ----------------PLA---------------------------YPKPPEAPAPPP-- 170
                            PLA                            P PP APAP P  
Sbjct: 1276 PSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPS 1335

Query: 171  -GLPAAATAASV-----IPLPGRGLPLPPSNLPSIHSLLYQL------NQQCQAPGAAP- 217
             GLPA            +P P  G    P   P++   L +L           APGAAP 
Sbjct: 1336 SGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPL 1395

Query: 218  --------------PACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGA 263
                          PA   M IP+ SP    PV S  S+  S++  LP     T L   A
Sbjct: 1396 TISSPLHVPSSLPGPASSPMPIPNSSPLA-SPVSSTVSVPLSSS--LP-ISVPTTLPAPA 1451

Query: 264  TQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYER 323
            +  LT+  +A P   + SG   LL    PP  P  P      S   S +           
Sbjct: 1452 SAPLTIPISA-PLTVSASG-PALLTSVTPPLAPVVPAAPGPPSLAPSGA----------S 1499

Query: 324  ASGSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPTSDYYNPAAAVVVTELGP--GAARELA 381
             S S L  G+    S +  Q    P + +L+ PTS +     + V     P    A  LA
Sbjct: 1500 PSASALTLGLATAPSLSSSQ---TPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALA 1556

Query: 382  GPPADALSGLPSKSVCNTSVLSSSLQSLEYLINDIRP 418
             P   A    P+ +    S+L+ +  + + L   + P
Sbjct: 1557 SPFPSA----PNPAPAQASLLAPASSASQALATPLAP 1589


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 50/175 (28%), Positives = 61/175 (34%), Gaps = 46/175 (26%)

Query: 147 PYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPP-SNLPSIHSLLYQ 205
           P P PS  GP   P PP    PPP            P  GRG P PP S  P+       
Sbjct: 278 PPPPPSRGGPPPPPPPPHNSGPPPP-----------PARGRGAPPPPPSRAPTA------ 320

Query: 206 LNQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQ 265
                 AP   PP+   +A+P P P +  P P  P++  SA +G P              
Sbjct: 321 ------APPPPPPSRPSVAVPPPPPNRMYPPPP-PALPSSAPSGPPP---------PPPS 364

Query: 266 ALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGRA 320
            L +   A P             P  PPPPP  P      S    + P   G +A
Sbjct: 365 VLGVGPVAPPP------------PPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKA 407



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 46/155 (29%), Positives = 57/155 (36%), Gaps = 46/155 (29%)

Query: 146 APYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAASVIPLPGRGL-PLPPSNLPSIHSLLY 204
           AP P P + G    P PP   + PP  PA           GRG  P PPS  P+      
Sbjct: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPAR----------GRGAPPPPPSRAPT------ 319

Query: 205 QLNQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGAT 264
                  AP   PP+   +A+P P P +  P P  P++  SA +G P             
Sbjct: 320 ------AAPPPPPPSRPSVAVPPPPPNRMYPPPP-PALPSSAPSGPP---------PPPP 363

Query: 265 QALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQP 299
             L +   A P             P  PPPPPP P
Sbjct: 364 SVLGVGPVAPP-------------PPPPPPPPPGP 385



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 42/129 (32%), Positives = 50/129 (38%), Gaps = 27/129 (20%)

Query: 149 PVPSTLGPLAYPKPPE-AP--APPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQ 205
           P P   G  A P PP  AP  APPP  P+  + A   P P R  P PP  LPS       
Sbjct: 300 PPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPS------- 352

Query: 206 LNQQCQAPGAAPPACQGMA-----IPHPSPAKHGPVP----------SFPSMAYSAAAGL 250
                  P   PP+  G+       P P P   GP P            P+ A + AA L
Sbjct: 353 --SAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALL 410

Query: 251 PDCRKGTEL 259
              R+G +L
Sbjct: 411 DQIREGAQL 419


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 51/151 (33%), Positives = 57/151 (37%), Gaps = 25/151 (16%)

Query: 112 SSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTL-GPLAYPKPP------E 164
           SS  + P G A S      G  T   P  +  G+   P PS+L G  A P PP       
Sbjct: 619 SSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG-IPSPSSLPGGTAIPPPPPLPGSAR 677

Query: 165 APAPPPGLP-AAATAASVIPLPGR-GLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPA--C 220
            P PPP LP +A       PLPG  G+P PP  LP               PG  PP    
Sbjct: 678 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG-------------GPGIPPPPPFP 724

Query: 221 QGMAIPHPSPAKHGPVPSFPSMAYSAAAGLP 251
            G  IP P P    P P        AA  LP
Sbjct: 725 GGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 755



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 47/190 (24%), Positives = 66/190 (34%), Gaps = 36/190 (18%)

Query: 111 SSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPP 170
           +++ T  P+ P+++ +  A        P     G    P P+       P PP  P PPP
Sbjct: 558 AAAITVPPSVPSRAPVPPAP-------PLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP 610

Query: 171 GLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSP 230
            LP     +S   LPG     PP  L    ++              PP  +G+ IP PS 
Sbjct: 611 PLPGGVCISSPPSLPGGTAISPPPPLSGDATI-----------PPPPPLPEGVGIPSPSS 659

Query: 231 AKHG-PVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWP 289
              G  +P  P +  SA    P        G              P    ++G+      
Sbjct: 660 LPGGTAIPPPPPLPGSARIPPPPPPLPGSAG---------IPPPPPPLPGEAGM------ 704

Query: 290 QKPPPPPPQP 299
             PPPPPP P
Sbjct: 705 --PPPPPPLP 712



 Score = 32.3 bits (72), Expect = 0.90
 Identities = 23/59 (38%), Positives = 25/59 (42%), Gaps = 13/59 (22%)

Query: 289 PQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYE---RASGS-------PLNCGVGLPT 337
           P  PPPPPP PL    G    S  P   GG A       SG        PL  GVG+P+
Sbjct: 601 PPPPPPPPPPPL---PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPS 656


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 51/151 (33%), Positives = 57/151 (37%), Gaps = 25/151 (16%)

Query: 112 SSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTL-GPLAYPKPP------E 164
           SS  + P G A S      G  T   P  +  G+   P PS+L G  A P PP       
Sbjct: 628 SSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVG-IPSPSSLPGGTAIPPPPPLPGSAR 686

Query: 165 APAPPPGLP-AAATAASVIPLPGR-GLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPA--C 220
            P PPP LP +A       PLPG  G+P PP  LP               PG  PP    
Sbjct: 687 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPG-------------GPGIPPPPPFP 733

Query: 221 QGMAIPHPSPAKHGPVPSFPSMAYSAAAGLP 251
            G  IP P P    P P        AA  LP
Sbjct: 734 GGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 764



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 47/190 (24%), Positives = 66/190 (34%), Gaps = 36/190 (18%)

Query: 111 SSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPP 170
           +++ T  P+ P+++ +  A        P     G    P P+       P PP  P PPP
Sbjct: 567 AAAITVPPSVPSRAPVPPAP-------PLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPP 619

Query: 171 GLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSP 230
            LP     +S   LPG     PP  L    ++              PP  +G+ IP PS 
Sbjct: 620 PLPGGVCISSPPSLPGGTAISPPPPLSGDATI-----------PPPPPLPEGVGIPSPSS 668

Query: 231 AKHG-PVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWP 289
              G  +P  P +  SA    P        G              P    ++G+      
Sbjct: 669 LPGGTAIPPPPPLPGSARIPPPPPPLPGSAG---------IPPPPPPLPGEAGM------ 713

Query: 290 QKPPPPPPQP 299
             PPPPPP P
Sbjct: 714 --PPPPPPLP 721



 Score = 32.3 bits (72), Expect = 0.90
 Identities = 23/59 (38%), Positives = 25/59 (42%), Gaps = 13/59 (22%)

Query: 289 PQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYE---RASGS-------PLNCGVGLPT 337
           P  PPPPPP PL    G    S  P   GG A       SG        PL  GVG+P+
Sbjct: 610 PPPPPPPPPPPL---PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPS 665


>gi|28872796 CCAAT/enhancer binding protein beta [Homo sapiens]
          Length = 345

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 55/183 (30%), Positives = 66/183 (36%), Gaps = 26/183 (14%)

Query: 215 AAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLA-GAA 273
           AAPPA      P P+PA  G    F S  +S   G  +C+K  E G  +   L  A GA 
Sbjct: 99  AAPPA------PAPAPASSGQHHDFLSDLFSDDYGGKNCKKPAEYGYVSLGRLGAAKGAL 152

Query: 274 KPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYERASGSPLNCGV 333
            P  +A       L P  PPPPPP  L+A  G       P  C  +    A G       
Sbjct: 153 HPGCFAP------LHPPPPPPPPPAELKAEPGF-----EPADCKRKEEAGAPGGGAGMAA 201

Query: 334 GLPTSFTVG-QYFAAPWNSVLVTPTSDYYNPAAAVVVTELGPGAARELAGPPADALSGLP 392
           G P +      Y A P  S     TS   +P          P  A   A P A      P
Sbjct: 202 GFPYALRAYLGYQAVPSGSSGSLSTSSSSSPPGT-------PSPADAKAPPTACYAGAAP 254

Query: 393 SKS 395
           + S
Sbjct: 255 APS 257


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 55/163 (33%), Positives = 60/163 (36%), Gaps = 31/163 (19%)

Query: 113 SSTAAPAG---PAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPP 169
           SS AAPA    P  SVL  +      L  AA Q    P      LGPLA       P PP
Sbjct: 265 SSAAAPASVETPLNSVLGDSSASEPGLQ-AASQPAETPSQQGIVLGPLA-------PPPP 316

Query: 170 PGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPS 229
           P LP     ASV   P  G P PP  LPS              P   PP       P P 
Sbjct: 317 PPLPPGPAQASVALPPPPG-PPPPPPLPSTG----------PPPPPPPPPLPNQVPPPPP 365

Query: 230 PAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGA 272
           P    P P  P+  +  A+   D R  T L      A  +AGA
Sbjct: 366 PP---PAPPLPASGFFLASMSEDNRPLTGL------AAAIAGA 399



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 27/117 (23%), Positives = 40/117 (34%), Gaps = 5/117 (4%)

Query: 86  GQRYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGI 145
           G + +  P  T   QG+  ++           P GPA++ +           P     G 
Sbjct: 290 GLQAASQPAETPSQQGI--VLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGP 347

Query: 146 APYPVPSTLG---PLAYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSI 199
            P P P  L    P   P PP  P P  G   A+ +    PL G    +  + L  +
Sbjct: 348 PPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLRKV 404


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 55/163 (33%), Positives = 60/163 (36%), Gaps = 31/163 (19%)

Query: 113 SSTAAPAG---PAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPP 169
           SS AAPA    P  SVL  +      L  AA Q    P      LGPLA       P PP
Sbjct: 265 SSAAAPASVETPLNSVLGDSSASEPGLQ-AASQPAETPSQQGIVLGPLA-------PPPP 316

Query: 170 PGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPS 229
           P LP     ASV   P  G P PP  LPS              P   PP       P P 
Sbjct: 317 PPLPPGPAQASVALPPPPG-PPPPPPLPSTG----------PPPPPPPPPLPNQVPPPPP 365

Query: 230 PAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGA 272
           P    P P  P+  +  A+   D R  T L      A  +AGA
Sbjct: 366 PP---PAPPLPASGFFLASMSEDNRPLTGL------AAAIAGA 399



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 27/117 (23%), Positives = 40/117 (34%), Gaps = 5/117 (4%)

Query: 86  GQRYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGI 145
           G + +  P  T   QG+  ++           P GPA++ +           P     G 
Sbjct: 290 GLQAASQPAETPSQQGI--VLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGP 347

Query: 146 APYPVPSTLG---PLAYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSI 199
            P P P  L    P   P PP  P P  G   A+ +    PL G    +  + L  +
Sbjct: 348 PPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLRKV 404


>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 490

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 59/240 (24%), Positives = 83/240 (34%), Gaps = 27/240 (11%)

Query: 110 VSSSSTAAPA--GPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPA 167
           VSS  +  P+      S+L       + +      V   P  VPS L  +  P P + P+
Sbjct: 135 VSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVPSP-PSDVPS 193

Query: 168 PP---PGLPAAATAASVIPLPGRGLPL------PPSNLPSIHSLLYQLNQQCQAPGAAPP 218
           PP   P  P+     S +P P   +PL      PPS++PS+ S +  L+     P   P 
Sbjct: 194 PPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPSLSGVPSPPSDVPS 253

Query: 219 ACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGY 278
              G+  P    +    VPS  S   S  + +P                 L+G   P   
Sbjct: 254 LLSGVPSPPSDISPPSDVPSLLSDVPSLPSDVPS---------------LLSGVPSPPSD 298

Query: 279 ADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYERASGSPLNCGVGLPTS 338
             S L  +  P    P PP  +   SG         +         S  PL  GV  P S
Sbjct: 299 VPSLLSDVPSPPSDVPSPPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSGVPSPLS 358



 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 46/207 (22%), Positives = 76/207 (36%), Gaps = 31/207 (14%)

Query: 104 AIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPP 163
           +++    S  S  +P     S+L       + +      V   P  VPS L  +  P P 
Sbjct: 253 SLLSGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPSP-PS 311

Query: 164 EAPAPPPGLPAAA---TAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPAC 220
           + P+PP  +P  +   +  S +P P   +P PPS++P +  +   L+      G   P  
Sbjct: 312 DVPSPPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSGVPSPLSDVPLLSGVPSPPS 371

Query: 221 Q----------------GMAIPH--PSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQG 262
                             +  PH    P+    VPS  S   S+ +G+P    G  +  G
Sbjct: 372 DVPSLLMSPHRLLMSHYSLVSPHRLDVPSLLSDVPSLLSGVPSSPSGVPSLPSGVPILSG 431

Query: 263 ATQALTLAGAAKPAGY-ADSGLDYLLW 288
                     + P+G  + SG+   LW
Sbjct: 432 V--------PSLPSGVPSPSGVPITLW 450



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 9/112 (8%)

Query: 149 PVPSTLGPLAYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQ 208
           P  S + P   P  P  P   P     +    ++     G+P PPS++PS+ S +  L  
Sbjct: 74  PHYSLVSPQYSPVSPHCPLVSPHYSLVSPHRPLVSPLLSGVPSPPSDVPSLLSGVPSLPS 133

Query: 209 QCQAPGAAPPACQG------MAIPHPS---PAKHGPVPSFPSMAYSAAAGLP 251
              +P +  P+           +P P    P+    VPS PS   S  +G+P
Sbjct: 134 DVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVP 185


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 74/250 (29%), Positives = 88/250 (35%), Gaps = 50/250 (20%)

Query: 92   YPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVP 151
            +P HT G  G LA      S S+   PA P      S       LS   V      YP P
Sbjct: 1316 HPPHTPGLCGSLA-----KSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAP 1370

Query: 152  S-TLGPLAYPKPPEAP---APPPGLPAAATAASVIPLP-GR----------------GLP 190
            S +L     P+ P       P    P+      V PLP GR                GLP
Sbjct: 1371 SPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLP 1430

Query: 191  LP-PSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPVP---SFPSMAYSA 246
            LP P  LP   +L   L  Q +AP   PP         P P K  P     S PSM  S 
Sbjct: 1431 LPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSML-SL 1489

Query: 247  AAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSG------LDYL----------LWPQ 290
               L     G  LG+   + L L G  +   +  +       LD+           L PQ
Sbjct: 1490 DGPLVRPPAGAALGR---ELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQ 1546

Query: 291  KPPPPPPQPL 300
             PPPPPP P+
Sbjct: 1547 PPPPPPPPPV 1556



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 36/113 (31%), Positives = 40/113 (35%), Gaps = 32/113 (28%)

Query: 138 PAAVQVGIAPYPVPSTLGP-LAYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNL 196
           P  V  G A    PS L P L  P PP  P  PP  P         P P  G P+PP   
Sbjct: 659 PMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPP--------PPPQPGFPMPPPLP 710

Query: 197 PSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPS-PAKHG--------PVPSFP 240
           P               P   PPA   + +P P  PA  G        P+P FP
Sbjct: 711 P--------------PPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFP 749



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 31/90 (34%), Positives = 36/90 (40%), Gaps = 18/90 (20%)

Query: 108 AAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPA 167
           AAV++ S  AP  P              L P      + P P P    P  +P PP  P 
Sbjct: 667 AAVAAPSVLAPTLP--------------LPPPPGFPPLPPPPPPPPPQP-GFPMPPPLPP 711

Query: 168 PPPGLPAAATAASVIPLPGRGLPLPPSNLP 197
           PPP  P A  A +V P P   LP PP   P
Sbjct: 712 PPPPPPPAHPAVTVPPPP---LPAPPGVPP 738



 Score = 33.9 bits (76), Expect = 0.31
 Identities = 39/143 (27%), Positives = 56/143 (39%), Gaps = 15/143 (10%)

Query: 117  APAGPAKSVLKSAEGKRTKLSPAAV---QVGIAPYP---VPSTLGP-LAYPKPPEAPAPP 169
            +P  PAK V       R  LSP       + + P P   +P  L P L  P+PP  P+PP
Sbjct: 1240 SPEPPAKEV-----EARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPP 1294

Query: 170  PGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQC--QAPGAAPPACQGMA-IP 226
            P       +   +P        PP       SL    + +     PG  PP   G + + 
Sbjct: 1295 PEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLS 1354

Query: 227  HPSPAKHGPVPSFPSMAYSAAAG 249
              SP   G   S+P+ + S ++G
Sbjct: 1355 LSSPQVPGSPFSYPAPSPSLSSG 1377



 Score = 29.6 bits (65), Expect = 5.9
 Identities = 47/195 (24%), Positives = 62/195 (31%), Gaps = 24/195 (12%)

Query: 108  AAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPA 167
            AA+       P  P   V  S    RT      +    A  P P        P PP+ P 
Sbjct: 1500 AALGRELLLLPGQPQTPVFPSTHDPRT----VTLDFRNAGIPAPPP------PLPPQPPP 1549

Query: 168  PPPGLPAAATAASVIPL----PGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPP--ACQ 221
            PPP  P   T      L    P   +P  P     +     +L  + + P   PP    +
Sbjct: 1550 PPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMEL-AKSRGPWRRPPKKRHE 1608

Query: 222  GMAIPHPSPAKHGPVPSF-PSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYAD 280
             +  P  SP    P P F P   +     L D   G   G        L    +     D
Sbjct: 1609 DLVPPAGSPELSPPQPLFRPRSEFEEMTILYDIWNG---GIDEEDIRFLCVTYERLLQQD 1665

Query: 281  SGLDYL---LWPQKP 292
            +G+D+L   LW   P
Sbjct: 1666 NGMDWLNDTLWVYHP 1680



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 63/256 (24%), Positives = 85/256 (33%), Gaps = 50/256 (19%)

Query: 80  NGYDTGGQR---YSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAE----GK 132
           N  + GG+    +SP P  + G   L          SS A P  P  S+    E     +
Sbjct: 460 NSMELGGRPTFGWSPEPCDSPGTPTL---------ESSPAGPEKPHDSLDSRIEMLLKEQ 510

Query: 133 RTKL-------SPAAVQVGIAPYPVPST----LGPLAYPKPP--EAPAPPPGLPAAATAA 179
           RTKL       S   +Q+  +P    S+    L P      P    P PP   P++    
Sbjct: 511 RTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLE 570

Query: 180 SVIPLP------------GRG-LPLPPSNLPSIHSLLYQLNQQC-QAPGAAPPACQGMAI 225
            + P P            G G  P P    P    LL Q  +      G   P  + M  
Sbjct: 571 DISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDE 630

Query: 226 PHPSPAKHGPVPS--FPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGL 283
              S  +   +     PS   ++A    DC K   +  GA  A+       P        
Sbjct: 631 GQQSSGEDMEISDDEMPSAPITSA----DCPKPMVVTPGAA-AVAAPSVLAPTLPLPPPP 685

Query: 284 DYLLWPQKPPPPPPQP 299
            +   P  PPPPPPQP
Sbjct: 686 GFPPLPPPPPPPPPQP 701


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 65/236 (27%), Positives = 93/236 (39%), Gaps = 40/236 (16%)

Query: 102 LLAIVKAAVSSSSTAAPAGPAKSV--LKSAEGKRTKLSP--AAVQVGIAPYPVPSTLGPL 157
           ++ +V+A + S+ T  P     +V  L SA   +  +S   A+ ++     P P+T    
Sbjct: 454 VVGVVEALIQSADTLFPGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAVPTPATTPA- 512

Query: 158 AYPKPPEAPAPPPGLPAAAT---AASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPG 214
             P P  APAP P L +AAT     S +P P    P    + P   + +  + ++ + P 
Sbjct: 513 --PAPAPAPAPAPALASAATKERTESEVP-PRPASPKVTRSPPETAAPVEDMARRTKRPA 569

Query: 215 AAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAK 274
            A P         P P   G   S P+      +G P          G  QAL       
Sbjct: 570 PARPTM-------PPPQVSGSRSSPPAPPLPPGSGSP----------GTPQAL------- 605

Query: 275 PAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYERASGSPLN 330
           P     S L     P   PP PPQP R  S  + AS SP + G      AS SP++
Sbjct: 606 PRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPG-----PASPSPVS 656


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 69/253 (27%), Positives = 85/253 (33%), Gaps = 56/253 (22%)

Query: 162  PPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQ 221
            PPE P PPP  PA      +  LP    PLPP               + + P A PP   
Sbjct: 1188 PPELPPPPP--PAEPPPTDLAHLP----PLPPPE------------GEARKP-AKPPVS- 1227

Query: 222  GMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADS 281
                  P P    PVP          +  P  +K    G G+ +     G   P      
Sbjct: 1228 ------PKPVLTQPVPKLQG------SPTPTSKKVPLPGPGSPEVKRAHGTPPPVS---- 1271

Query: 282  GLDYLLWPQKPPPPP--PQPLRAYSG--STVASKSPEACGGRAYERASGSPLNCGVGLPT 337
                     KPPPPP  P+P++A +G  S  A  SP     R    A   P      L  
Sbjct: 1272 --------PKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGA 1323

Query: 338  SFTVGQYFAAPWNSVLVTPTSDYYNPAAAVVVTELGPGAARELAGPPADALSGLPSKSVC 397
            S        AP   V   P       AAA       P A  E A P   A   L   S C
Sbjct: 1324 SPAKPPSPGAPALHVPAKPP----RAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSAC 1379

Query: 398  NTSVLSSSLQSLE 410
                L+++LQ++E
Sbjct: 1380 ----LAAALQAVE 1388



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 52/203 (25%), Positives = 71/203 (34%), Gaps = 17/203 (8%)

Query: 121  PAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAAS 180
            P  SV  +  G   +  PA+ Q G    P P    P A P P +    PP  P    A  
Sbjct: 1165 PPLSVYHNGTGT-VRRRPASEQAGPPELPPPP---PPAEPPPTDLAHLPPLPPPEGEARK 1220

Query: 181  VIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPG-AAPPACQGMAIPHPSPAKHGPVPSF 239
                P    P+    +P +       +++   PG  +P   +    P P   K  P P+ 
Sbjct: 1221 PAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTA 1280

Query: 240  PSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPP---- 295
            P     A AGLP    G        +    A A  P      G      P KPP P    
Sbjct: 1281 PKPV-KAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGAS----PAKPPSPGAPA 1335

Query: 296  ---PPQPLRAYSGSTVASKSPEA 315
               P +P RA + +  A+ +P A
Sbjct: 1336 LHVPAKPPRAAAAAAAAAAAPPA 1358



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 46/160 (28%), Positives = 56/160 (35%), Gaps = 34/160 (21%)

Query: 120  GPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLG-PLAYPKPPEAPAPPPGLPAAATA 178
            GP    +K A G    +SP       AP PV +  G P     P  AP+P    PAA   
Sbjct: 1254 GPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAA--- 1310

Query: 179  ASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQGMAIPHPSPAKHGPV-- 236
                      L  PP   PS+            A  A PP+         +PA H P   
Sbjct: 1311 ----------LAKPPGTPPSL-----------GASPAKPPS-------PGAPALHVPAKP 1342

Query: 237  PSFPSMAYSAAAGLPDCRKGTELGQGATQALTLAGAAKPA 276
            P   + A +AAA  P   +G   G  A Q L    A   A
Sbjct: 1343 PRAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAA 1382



 Score = 36.6 bits (83), Expect = 0.048
 Identities = 54/188 (28%), Positives = 73/188 (38%), Gaps = 40/188 (21%)

Query: 160 PKPPEAPAPPPGLPAAATAASVIP----LPGRGLPLPPSNLPSI---HSLLYQLNQQCQ- 211
           P  P+A   P G PA ATA  V P    LP    P+ P +LP         Y L Q  + 
Sbjct: 785 PGSPQALGGPHG-PAPATA-KVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEG 842

Query: 212 -----APGAAPP----ACQGMAIPHPSPAKHG----------------PVPSFPSMAYSA 246
                APG APP    A   + +P  + A+ G                  P    +   A
Sbjct: 843 EVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPA 902

Query: 247 AAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGS 306
           AAG P       +G+  +     AGA K    + S   + + P+K  PPPP P R+ S  
Sbjct: 903 AAG-PYATVQRRVGRSHSVRAP-AGADKNVNRSQS---FAVRPRKKGPPPPPPKRSSSAL 957

Query: 307 TVASKSPE 314
             A+ + E
Sbjct: 958 ASANLADE 965



 Score = 33.9 bits (76), Expect = 0.31
 Identities = 32/116 (27%), Positives = 41/116 (35%), Gaps = 11/116 (9%)

Query: 106  VKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEA 165
            VKA     S +A   PA S  +       K       +G +P   PS   P  +      
Sbjct: 1284 VKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALH-----V 1338

Query: 166  PAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPPACQ 221
            PA PP   AAA AA+  P      P PP       S   +L +      AA  A +
Sbjct: 1339 PAKPPRAAAAAAAAAAAP------PAPPEGASPGDSARQKLEETSACLAAALQAVE 1388


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 74/289 (25%), Positives = 100/289 (34%), Gaps = 57/289 (19%)

Query: 61  KIFPTNIRVPQHKHLSRTVNGYDTGGQRYSPYPQHTAGYQGLLAIVKAAVSSSSTAAPAG 120
           K+ P   +V    HL    N    G +R  P  +  A    +  +  AA+S  S      
Sbjct: 168 KVLPPLEQVWNLLHLEHKRN---YGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLS 224

Query: 121 PAKSVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAAS 180
           P     +    ++T L P    + + P P+P        P PP  P PPP LP  AT+  
Sbjct: 225 PGGKRRRGCNSEQTGLPPG---LPLPPPPLP--------PPPPPPPPPPPPLPGLATS-- 271

Query: 181 VIPLPGRGLPLPPSNL--PSIHSLLYQLNQQCQAPGAAPPACQGM--AIPHP-------- 228
                      PP  L  P + S L+      +  G+APP  Q    ++PHP        
Sbjct: 272 -----------PPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAY 320

Query: 229 --SPAKHGPVPSFPSMAYSAAAG------LPDCR-KGTELGQGATQALTLAGAAKPAGYA 279
              P  H  VP+ P        G      LP  R  G++L +   Q   +  +  PA   
Sbjct: 321 TAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATT 380

Query: 280 DSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYERASGSP 328
                    P  P  PP  P    S S   S S    G R  E   G P
Sbjct: 381 ------ACVPYAPSRPPGLPGTTTSSS---SSSSSNTGLRGVEPNPGIP 420



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 51/229 (22%), Positives = 81/229 (35%), Gaps = 43/229 (18%)

Query: 90  SPYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYP 149
           SP+P  TA      A+     ++++T            +A  +  K  P A+       P
Sbjct: 734 SPFPTDTAPTTTAPAVAVTTTTTTTTTT----------TATQEEEKKPPPAL-------P 776

Query: 150 VPSTLGPLAYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQ 209
            P  L     P  P+ P PPP                   P P S L S+ S+L      
Sbjct: 777 PPPPLAKFPPPSQPQPPPPPP-------------------PSPASLLKSLASVLEGQKYC 817

Query: 210 CQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQALTL 269
            +  GAA     G   P P+  ++ P P   + A    +  P  +   +    ++   + 
Sbjct: 818 YRGTGAAVSTRPG---PLPT-TQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFST 873

Query: 270 AGA--AKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEAC 316
           +G   A+     +  +   + P +PPPP   P  A S S V  +   AC
Sbjct: 874 SGGPWARERRAGEEPVPGPMTPTQPPPPLSLP-PARSESEVLEEISRAC 921



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 59/234 (25%), Positives = 84/234 (35%), Gaps = 50/234 (21%)

Query: 157 LAYPKPPEA-PAPPPGLPAAATAASVIP----LPGRG------LPLP------------- 192
           +++PK PE  P PPPG P +     V P    LP RG       P P             
Sbjct: 632 VSFPKTPEVGPGPPPG-PLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKI 690

Query: 193 -PSNLPSI-----HSLLYQLNQQCQAPGAA--PPACQGMA-IPHPSPAKHGPVPSFPSMA 243
            P  L +I      S+  +  QQ    G A  PP  +  A +  P P    P  + P++A
Sbjct: 691 LPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVA 750

Query: 244 YSAAAGLPDCRKGTELGQGATQALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAY 303
            +           T+      +       A P     +       PQ PPPPPP P    
Sbjct: 751 VTTTTTTTTTTTATQ------EEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSP---- 800

Query: 304 SGSTVASKSPEACGGRAYERASGSPLNCGVG-LPTSFTVGQYFAAPWNSVLVTP 356
             S + S +    G +   R +G+ ++   G LPT+    QY   P +     P
Sbjct: 801 -ASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTT----QYSPGPPSGATALP 849



 Score = 33.1 bits (74), Expect = 0.53
 Identities = 65/261 (24%), Positives = 89/261 (34%), Gaps = 43/261 (16%)

Query: 91  PYPQHTAGYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPV 150
           P P +TA   G   +V AA        P   +   L +     + L  + VQ       +
Sbjct: 316 PAPAYTAHPPGH-RLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRS----RM 370

Query: 151 PSTLGPLAYPK-PPEAPAPPPGLPAAATAASVIPLPGRGL----PLP----------PSN 195
            S++ P A     P AP+ PPGLP   T++S       GL    P P          P+ 
Sbjct: 371 DSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPAL 430

Query: 196 LPSIHSLLYQLNQQCQAPG-AAPPACQGMAIPHPSPAKHGPVPSF------PSMAYSAAA 248
             S H  L       + P   AP A   +++P P P+   P P        P  A+    
Sbjct: 431 EVSHHGRLGPSAHSSRKPFLGAPAATPHLSLP-PGPSSPPPPPCPRLLRPPPPPAWLKG- 488

Query: 249 GLPDCRKGTELGQGATQALT-LAGAAKPAGYADSGLDYLLWP-----------QKPPPPP 296
             P CR   E G+   +      G  +PA       +  L P              PP P
Sbjct: 489 --PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTP 546

Query: 297 PQPLRAYSGSTVASKSPEACG 317
           P P  + S S   S S    G
Sbjct: 547 PTPTTSSSNSNSGSHSSSPAG 567


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 70/267 (26%), Positives = 97/267 (36%), Gaps = 39/267 (14%)

Query: 62  IFPTNIRVPQHKHLSRTVNGYDTGGQRYSPYPQ-HTAGYQGLLAIV----KAAVSSSSTA 116
           + PT    P     SR    +        P+PQ +  G  G+L+      K   ++SS  
Sbjct: 189 VTPTGYHAPMEPPTSRM---FQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVG 245

Query: 117 APAGPAK--------SVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPK-PPEAPA 167
            P G  +        SV  S         P    VG     +PS   P  +P   P  P 
Sbjct: 246 GPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGN--LPSAPPPANFPHVTPNLPP 303

Query: 168 PPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPP-ACQGMAIP 226
           PP   P    +AS    PG G    P +LPS H++   +      P   P  A    ++P
Sbjct: 304 PPALRPLNNASASP---PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP 360

Query: 227 HPSPAKHGPVPSFP---SMAYSAAAGLPDCRKGTELGQ-GATQAL-----------TLAG 271
             S +   P   FP   S + SAAA        +      A+QAL           +L+ 
Sbjct: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV 420

Query: 272 AAKPAGYADSGL-DYLLWPQKPPPPPP 297
           + +P  Y    L    +W Q PPPPPP
Sbjct: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPP 447



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 52/190 (27%), Positives = 69/190 (36%), Gaps = 22/190 (11%)

Query: 151 PSTLGPLAYPKPPEAPAPP-PGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQ--LN 207
           PS   P + P+ PEA   P P +      A + P   R    PP   P  H  LY     
Sbjct: 167 PSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPG-APPPHPQLYPGGTG 225

Query: 208 QQCQAPGAAPPAC-QGMAIPHPSPAKHGPVPSFP-SMAYSAAAGLPDCRKGTELGQGATQ 265
                P   P       ++  P+  K  P P+ P S++ S A+G P  +  T    G   
Sbjct: 226 GVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGN- 284

Query: 266 ALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYERAS 325
              L  A  PA +        + P  PPPP  +PL        AS SP   G +      
Sbjct: 285 ---LPSAPPPANFPH------VTPNLPPPPALRPLNN------ASASPPGLGAQPLPGHL 329

Query: 326 GSPLNCGVGL 335
            SP   G G+
Sbjct: 330 PSPHAMGQGM 339



 Score = 36.6 bits (83), Expect = 0.048
 Identities = 61/244 (25%), Positives = 80/244 (32%), Gaps = 52/244 (21%)

Query: 147 PYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQL 206
           PY +  +LG L    P  A  PPP    + + A        G P+  S+  S        
Sbjct: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAG-----PNGPPVSSSSNSS------SS 577

Query: 207 NQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQA 266
             Q   P + P   QG   P  +P    PVP                   T     AT +
Sbjct: 578 TSQGSYPCSHPSPSQG---PQGAPYPFPPVP-------------------TVTTSSATLS 615

Query: 267 LTLAG-AAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYERAS 325
             +A  A+ PAGY  +          PP PPP   RA S     + +P            
Sbjct: 616 TVIATVASSPAGYKTA---------SPPGPPPYGKRAPSPGAYKTATPPG-------YKP 659

Query: 326 GSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPT--SDYYNPAAAVVVTELGPGAARELAGP 383
           GSP +   G P  +      A P      +PT       PA    +  L P  A   +GP
Sbjct: 660 GSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP 719

Query: 384 PADA 387
           P  A
Sbjct: 720 PLSA 723



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 48/178 (26%), Positives = 58/178 (32%), Gaps = 47/178 (26%)

Query: 42  SPAELDAYAEKVANSPLSIKIF------PTNIRVPQH-KHLSRTVNGYDTGGQRYSPYPQ 94
           S A L      VA+SP   K        P   R P    + + T  GY  G    SP   
Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG----SPPSF 665

Query: 95  HTA---GYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVP 151
            T    GY+G             T+ PAGP                P +  VG  P P  
Sbjct: 666 RTGTPPGYRG-------------TSPPAGPGT------------FKPGSPTVGPGPLPPA 700

Query: 152 STLGPLAYPKPPEAPAPPPGL--------PAAATAASVIPLPGRGLPLPPSNLPSIHS 201
              G  + P PP APA  P L        PA        P+P    P PP  +  + S
Sbjct: 701 GPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPS 758


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 70/267 (26%), Positives = 97/267 (36%), Gaps = 39/267 (14%)

Query: 62  IFPTNIRVPQHKHLSRTVNGYDTGGQRYSPYPQ-HTAGYQGLLAIV----KAAVSSSSTA 116
           + PT    P     SR    +        P+PQ +  G  G+L+      K   ++SS  
Sbjct: 189 VTPTGYHAPMEPPTSRM---FQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVG 245

Query: 117 APAGPAK--------SVLKSAEGKRTKLSPAAVQVGIAPYPVPSTLGPLAYPK-PPEAPA 167
            P G  +        SV  S         P    VG     +PS   P  +P   P  P 
Sbjct: 246 GPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGN--LPSAPPPANFPHVTPNLPP 303

Query: 168 PPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQLNQQCQAPGAAPP-ACQGMAIP 226
           PP   P    +AS    PG G    P +LPS H++   +      P   P  A    ++P
Sbjct: 304 PPALRPLNNASASP---PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP 360

Query: 227 HPSPAKHGPVPSFP---SMAYSAAAGLPDCRKGTELGQ-GATQAL-----------TLAG 271
             S +   P   FP   S + SAAA        +      A+QAL           +L+ 
Sbjct: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV 420

Query: 272 AAKPAGYADSGL-DYLLWPQKPPPPPP 297
           + +P  Y    L    +W Q PPPPPP
Sbjct: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPP 447



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 52/190 (27%), Positives = 69/190 (36%), Gaps = 22/190 (11%)

Query: 151 PSTLGPLAYPKPPEAPAPP-PGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQ--LN 207
           PS   P + P+ PEA   P P +      A + P   R    PP   P  H  LY     
Sbjct: 167 PSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPG-APPPHPQLYPGGTG 225

Query: 208 QQCQAPGAAPPAC-QGMAIPHPSPAKHGPVPSFP-SMAYSAAAGLPDCRKGTELGQGATQ 265
                P   P       ++  P+  K  P P+ P S++ S A+G P  +  T    G   
Sbjct: 226 GVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGN- 284

Query: 266 ALTLAGAAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYERAS 325
              L  A  PA +        + P  PPPP  +PL        AS SP   G +      
Sbjct: 285 ---LPSAPPPANFPH------VTPNLPPPPALRPLNN------ASASPPGLGAQPLPGHL 329

Query: 326 GSPLNCGVGL 335
            SP   G G+
Sbjct: 330 PSPHAMGQGM 339



 Score = 36.6 bits (83), Expect = 0.048
 Identities = 61/244 (25%), Positives = 80/244 (32%), Gaps = 52/244 (21%)

Query: 147 PYPVPSTLGPLAYPKPPEAPAPPPGLPAAATAASVIPLPGRGLPLPPSNLPSIHSLLYQL 206
           PY +  +LG L    P  A  PPP    + + A        G P+  S+  S        
Sbjct: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAG-----PNGPPVSSSSNSS------SS 577

Query: 207 NQQCQAPGAAPPACQGMAIPHPSPAKHGPVPSFPSMAYSAAAGLPDCRKGTELGQGATQA 266
             Q   P + P   QG   P  +P    PVP                   T     AT +
Sbjct: 578 TSQGSYPCSHPSPSQG---PQGAPYPFPPVP-------------------TVTTSSATLS 615

Query: 267 LTLAG-AAKPAGYADSGLDYLLWPQKPPPPPPQPLRAYSGSTVASKSPEACGGRAYERAS 325
             +A  A+ PAGY  +          PP PPP   RA S     + +P            
Sbjct: 616 TVIATVASSPAGYKTA---------SPPGPPPYGKRAPSPGAYKTATPPG-------YKP 659

Query: 326 GSPLNCGVGLPTSFTVGQYFAAPWNSVLVTPT--SDYYNPAAAVVVTELGPGAARELAGP 383
           GSP +   G P  +      A P      +PT       PA    +  L P  A   +GP
Sbjct: 660 GSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP 719

Query: 384 PADA 387
           P  A
Sbjct: 720 PLSA 723



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 48/178 (26%), Positives = 58/178 (32%), Gaps = 47/178 (26%)

Query: 42  SPAELDAYAEKVANSPLSIKIF------PTNIRVPQH-KHLSRTVNGYDTGGQRYSPYPQ 94
           S A L      VA+SP   K        P   R P    + + T  GY  G    SP   
Sbjct: 610 SSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG----SPPSF 665

Query: 95  HTA---GYQGLLAIVKAAVSSSSTAAPAGPAKSVLKSAEGKRTKLSPAAVQVGIAPYPVP 151
            T    GY+G             T+ PAGP                P +  VG  P P  
Sbjct: 666 RTGTPPGYRG-------------TSPPAGPGT------------FKPGSPTVGPGPLPPA 700

Query: 152 STLGPLAYPKPPEAPAPPPGL--------PAAATAASVIPLPGRGLPLPPSNLPSIHS 201
              G  + P PP APA  P L        PA        P+P    P PP  +  + S
Sbjct: 701 GPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPS 758


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,346,331
Number of Sequences: 37866
Number of extensions: 1495272
Number of successful extensions: 18458
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 252
Number of HSP's successfully gapped in prelim test: 1185
Number of HSP's that attempted gapping in prelim test: 9813
Number of HSP's gapped (non-prelim): 6145
length of query: 452
length of database: 18,247,518
effective HSP length: 106
effective length of query: 346
effective length of database: 14,233,722
effective search space: 4924867812
effective search space used: 4924867812
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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