Search of human proteins with 142356950

Search of human proteins with 142356950

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|142356950 potassium channel tetramerisation domain
containing 14 [Homo sapiens]
         (255 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|142356950 potassium channel tetramerisation domain containing...   522   e-148
gi|23308551 potassium channel tetramerisation domain containing ...   143   2e-34
gi|71143104 potassium channel tetramerisation domain containing ...    79   5e-15
gi|38198663 potassium channel tetramerisation domain containing ...    77   1e-14
gi|189571693 potassium channel tetramerisation domain containing...    76   2e-14
gi|189571691 potassium channel tetramerisation domain containing...    76   2e-14
gi|55926200 potassium channel tetramerisation domain containing ...    71   8e-13
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       67   2e-11
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       67   2e-11
gi|194018443 potassium channel tetramerisation domain containing...    65   4e-11
gi|194018441 potassium channel tetramerisation domain containing...    65   4e-11
gi|194018439 potassium channel tetramerisation domain containing...    65   4e-11
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  65   4e-11
gi|39753959 potassium channel tetramerisation domain containing ...    65   4e-11
gi|19923973 potassium channel tetramerisation domain containing ...    65   7e-11
gi|30578412 potassium channel tetramerisation domain containing ...    64   1e-10
gi|13994353 potassium channel tetramerisation domain containing ...    62   4e-10
gi|9506651 potassium channel tetramerisation domain containing 5...    62   5e-10
gi|53829365 potassium channel tetramerisation domain containing ...    62   5e-10
gi|218505694 potassium channel tetramerisation domain containing...    61   8e-10
gi|209969708 potassium channel tetramerisation domain containing...    61   8e-10
gi|40217617 potassium channel tetramerisation domain containing ...    61   8e-10
gi|146198864 potassium channel tetramerisation domain containing...    59   3e-09
gi|46255026 potassium channel tetramerisation domain containing ...    58   7e-09
gi|169184031 PREDICTED: similar to potassium channel tetramerisa...    57   2e-08
gi|169179790 PREDICTED: similar to potassium channel tetramerisa...    57   2e-08
gi|169180181 PREDICTED: similar to potassium channel tetramerisa...    57   2e-08
gi|169234778 potassium channel tetramerisation domain containing...    57   2e-08
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...    55   6e-08
gi|45387953 potassium channel tetramerization domain containing ...    49   4e-06

>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score =  522 bits (1344), Expect = e-148
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MWQGCAVERPVGRMTSQTPLPQSPRPRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLA 60
           MWQGCAVERPVGRMTSQTPLPQSPRPRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLA
Sbjct: 1   MWQGCAVERPVGRMTSQTPLPQSPRPRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLA 60

Query: 61  EMFSSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPTQHIPEVYREAQFYEIKPLVK 120
           EMFSSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPTQHIPEVYREAQFYEIKPLVK
Sbjct: 61  EMFSSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPTQHIPEVYREAQFYEIKPLVK 120

Query: 121 LLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDA 180
           LLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDA
Sbjct: 121 LLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDA 180

Query: 181 YYSEVLCFLQDKKMFKSVVKFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKR 240
           YYSEVLCFLQDKKMFKSVVKFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKR
Sbjct: 181 YYSEVLCFLQDKKMFKSVVKFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKR 240

Query: 241 NEFHFNIYSFTFTWW 255
           NEFHFNIYSFTFTWW
Sbjct: 241 NEFHFNIYSFTFTWW 255


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score =  143 bits (360), Expect = 2e-34
 Identities = 95/240 (39%), Positives = 137/240 (57%), Gaps = 20/240 (8%)

Query: 34  VVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYL 93
           VV LN+GG   TT L TLR +  + LA MFS      TD+EGR+FIDR  T+F  +L++L
Sbjct: 52  VVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFL 111

Query: 94  RTGQV-PTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPGYSENLELM 152
           R+G + P + +  VY+EAQ+Y I PL++ LE+M  + GE+V R+ FL  +P Y ++LE +
Sbjct: 112 RSGDLPPRERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKV-RQAFLGLMPYYKDHLERI 170

Query: 153 VRLARAEAI--TARKSSVLVCLVETEEQ-DAYYSEVLCFLQ------DKKMFKS----VV 199
           V +AR  A+   AR + + VC+ + E     Y   +L  L+      D ++F+      V
Sbjct: 171 VEIARLRAVQRKARFAKLKVCVFKEEMPITPYECPLLNSLRFERSESDGQLFEHHCEVDV 230

Query: 200 KFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKRNEFHF----NIYSFTFTWW 255
            FGPW+AV D  DL+HCL  D+ AQG  V  +  +    K    H+     IY F  TWW
Sbjct: 231 SFGPWEAVADVYDLLHCLVTDLSAQGLTVDHQ-CIGVCDKHLVNHYYCKRPIYEFKITWW 289


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score = 78.6 bits (192), Expect = 5e-15
 Identities = 41/98 (41%), Positives = 59/98 (60%), Gaps = 4/98 (4%)

Query: 31  MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPIL 90
           MS  + LNVGG+ +TT+L TL  FP S L  MFS       D++G  FIDR    FR IL
Sbjct: 1   MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYIL 60

Query: 91  DYLRTGQVPT----QHIPEVYREAQFYEIKPLVKLLED 124
           ++LRT  +      Q +  + REA FY+++PL++ L++
Sbjct: 61  NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQE 98


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 62/180 (34%), Positives = 88/180 (48%), Gaps = 27/180 (15%)

Query: 10  PVGRMTSQTPLP-----QSPRPRRPT-MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMF 63
           P+  M S +  P      +P P  P+    VVELNVGG+ + T   TL   P S LA MF
Sbjct: 15  PISEMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMF 74

Query: 64  SSLA---------KASTDAEGRFFIDRPSTYFRPILDYLRTGQVP-TQHIPE---VYREA 110
           S  +         +   D+  RFFIDR    FR +LDYLR  Q+   +H PE   + REA
Sbjct: 75  SPSSPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREA 134

Query: 111 QFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLV 170
           +++++  LVKLL   P++       KQ  L   G   +LE  V    ++A+  R ++  V
Sbjct: 135 EYFQLTDLVKLLS--PKV------TKQNSLNDEGCQSDLEDNVSQGSSDALLLRGAAAAV 186


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 58/206 (28%), Positives = 100/206 (48%), Gaps = 18/206 (8%)

Query: 31  MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPIL 90
           M+  V LNVGG  +TT+L TL ++P S L  MF      + D +G +FIDR    FR +L
Sbjct: 10  MTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVL 69

Query: 91  DYLRTGQVPT----QHIPEVYREAQFYEIKPLVKLLEDMPQIFG----EQVSRKQFLLQV 142
           ++LRT ++      +    + +EA FY+I+PL++ L D   ++     E+V       ++
Sbjct: 70  NFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKL 129

Query: 143 PGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFG 202
             YS  + +++       IT +  S+L      E    Y+++    + D +  +    FG
Sbjct: 130 SKYSNPVAVIITQL---TITTKVHSLL------EGISNYFTKWNKHMMDTRDCQVSFTFG 180

Query: 203 PWKAVLDNSDLMHCLEMDIKAQGYKV 228
           P     + S  +H +E  I  QG+ +
Sbjct: 181 PCDYHQEVSLRVHLMEY-ITKQGFTI 205


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 58/206 (28%), Positives = 100/206 (48%), Gaps = 18/206 (8%)

Query: 31  MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPIL 90
           M+  V LNVGG  +TT+L TL ++P S L  MF      + D +G +FIDR    FR +L
Sbjct: 10  MTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVL 69

Query: 91  DYLRTGQVPT----QHIPEVYREAQFYEIKPLVKLLEDMPQIFG----EQVSRKQFLLQV 142
           ++LRT ++      +    + +EA FY+I+PL++ L D   ++     E+V       ++
Sbjct: 70  NFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKL 129

Query: 143 PGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFG 202
             YS  + +++       IT +  S+L      E    Y+++    + D +  +    FG
Sbjct: 130 SKYSNPVAVIITQL---TITTKVHSLL------EGISNYFTKWNKHMMDTRDCQVSFTFG 180

Query: 203 PWKAVLDNSDLMHCLEMDIKAQGYKV 228
           P     + S  +H +E  I  QG+ +
Sbjct: 181 PCDYHQEVSLRVHLMEY-ITKQGFTI 205


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 71.2 bits (173), Expect = 8e-13
 Identities = 46/97 (47%), Positives = 58/97 (59%), Gaps = 8/97 (8%)

Query: 34  VVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTD----AEGRFFIDRPSTYFRPI 89
           VVELNVGG+ + T   TL   P S L +MFS     + D    ++GRFFIDR    FR I
Sbjct: 26  VVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYI 85

Query: 90  LDYLRTGQVP-TQHIPE---VYREAQFYEIKPLVKLL 122
           LDYLR  QV    H PE   + REA+++++  LVKLL
Sbjct: 86  LDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 39/93 (41%), Positives = 54/93 (58%), Gaps = 4/93 (4%)

Query: 34  VVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYL 93
           +V LNVGG+  TT   T+++FP S+LA M     +      G+ F+DR    F  ILD+L
Sbjct: 6   LVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFL 65

Query: 94  RTGQ--VPTQHIP--EVYREAQFYEIKPLVKLL 122
           RT Q  +PT+      + REA FYE++ LV LL
Sbjct: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLVDLL 98


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 39/93 (41%), Positives = 54/93 (58%), Gaps = 4/93 (4%)

Query: 34  VVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYL 93
           +V LNVGG+  TT   T+++FP S+LA M     +      G+ F+DR    F  ILD+L
Sbjct: 6   LVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFL 65

Query: 94  RTGQ--VPTQHIP--EVYREAQFYEIKPLVKLL 122
           RT Q  +PT+      + REA FYE++ LV LL
Sbjct: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLVDLL 98


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 39/120 (32%), Positives = 69/120 (57%), Gaps = 9/120 (7%)

Query: 24  PRPRRPTMSTV-VELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDA-EGRFFIDR 81
           P P + T S   V ++VGG  +T++L TL K+P S+++ +F+       D+ +  +FIDR
Sbjct: 46  PLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDR 105

Query: 82  PSTYFRPILDYLRTGQV----PTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQ 137
               FR +L +LRT ++      +    +Y EA++Y+++P+V+ LE   Q   EQ  R++
Sbjct: 106 DGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQ---EQEQRRR 162


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 39/120 (32%), Positives = 69/120 (57%), Gaps = 9/120 (7%)

Query: 24  PRPRRPTMSTV-VELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDA-EGRFFIDR 81
           P P + T S   V ++VGG  +T++L TL K+P S+++ +F+       D+ +  +FIDR
Sbjct: 46  PLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDR 105

Query: 82  PSTYFRPILDYLRTGQV----PTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQ 137
               FR +L +LRT ++      +    +Y EA++Y+++P+V+ LE   Q   EQ  R++
Sbjct: 106 DGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQ---EQEQRRR 162


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 39/120 (32%), Positives = 69/120 (57%), Gaps = 9/120 (7%)

Query: 24  PRPRRPTMSTV-VELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDA-EGRFFIDR 81
           P P + T S   V ++VGG  +T++L TL K+P S+++ +F+       D+ +  +FIDR
Sbjct: 46  PLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDR 105

Query: 82  PSTYFRPILDYLRTGQV----PTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQ 137
               FR +L +LRT ++      +    +Y EA++Y+++P+V+ LE   Q   EQ  R++
Sbjct: 106 DGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQ---EQEQRRR 162


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 38/100 (38%), Positives = 53/100 (53%), Gaps = 2/100 (2%)

Query: 26  PRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTY 85
           P R     V+ LNVGG+  +T+  TL   P S  + + S       D  G  FIDR  T 
Sbjct: 12  PSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTV 71

Query: 86  FRPILDYLRTGQVPTQ--HIPEVYREAQFYEIKPLVKLLE 123
           F PIL++LRT ++  +  H   +  EAQFY + PLV+ L+
Sbjct: 72  FAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQ 111


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 51/125 (40%), Positives = 62/125 (49%), Gaps = 14/125 (11%)

Query: 37  LNVGGEFHTTTLGTL-RKFPGSKLAEMFSSLAKAST--DAEGRFFIDRPSTYFRPILDYL 93
           LNVGG + TTT  TL  K P S LA MF          D  G F IDR   YF PIL+YL
Sbjct: 93  LNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPILNYL 152

Query: 94  RTGQVPTQ---HIPEVYREAQFYEIKPLVKLLE-----DMPQIFGEQVSRKQ---FLLQV 142
           R GQ+      ++  V  EA+F+ I  L++ LE       P      +SRK+   FLL  
Sbjct: 153 RHGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNSQPPEDHSPISRKEFVRFLLAT 212

Query: 143 PGYSE 147
           P  SE
Sbjct: 213 PTKSE 217


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 64.7 bits (156), Expect = 7e-11
 Identities = 41/100 (41%), Positives = 58/100 (58%), Gaps = 6/100 (6%)

Query: 29  PTMSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLA--KASTDAEGRFFIDRPSTYF 86
           P    +VELNVGG+ + T   T+   P S L  MF+     + + D++GRFF+DR    F
Sbjct: 30  PLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLF 89

Query: 87  RPILDYLRTGQ-VPTQHIPE---VYREAQFYEIKPLVKLL 122
           R ILDYLR  Q V   + PE   + REA+++E+  LV+ L
Sbjct: 90  RYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 44/119 (36%), Positives = 61/119 (51%), Gaps = 6/119 (5%)

Query: 6   AVERPVGRMTSQTPLPQSPRPRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSS 65
           ++E P        P     +P  P  S  V+LNVGG  H TTL TL     + L  MFS 
Sbjct: 15  SLEAPKPSGLEPGPAAYGLKPLTPN-SKYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSG 72

Query: 66  LAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVP----TQHIPEVYREAQFYEIKPLVK 120
             +  TDA G   IDR   +F  IL+YLR G VP    T+ + E+  EA++Y ++ L++
Sbjct: 73  RVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIE 131


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 39/93 (41%), Positives = 54/93 (58%), Gaps = 5/93 (5%)

Query: 32  STVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILD 91
           S  V+LNVGG  + TT+ TL K   + L  MFS   +  TD+EG   IDR   +F  IL+
Sbjct: 31  SKYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILN 89

Query: 92  YLRTGQVP----TQHIPEVYREAQFYEIKPLVK 120
           YLR G VP     + I E+  EA++Y ++ LV+
Sbjct: 90  YLRDGAVPLPESRREIEELLAEAKYYLVQGLVE 122


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 41/103 (39%), Positives = 59/103 (57%), Gaps = 5/103 (4%)

Query: 27  RRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAE--GRFFIDRPST 84
           R  ++S  V LNVGG +  TT  TL + P S L  +  +     +D +  G + IDR  T
Sbjct: 38  RPGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPT 97

Query: 85  YFRPILDYLRTGQ-VPTQHIPE--VYREAQFYEIKPLVKLLED 124
           YF P+L+YLR G+ V  + + E  V  EA+FY I  L+KL++D
Sbjct: 98  YFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKD 140


>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 45/125 (36%), Positives = 62/125 (49%), Gaps = 12/125 (9%)

Query: 12  GRMTSQTPLPQSPRPRRPTMS------TVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSS 65
           GR  +    P  P P  P  +        V LNVGG +  TT  TL + P S L  +   
Sbjct: 45  GRPAAAVAQPLEPGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQ 104

Query: 66  L---AKASTDAEGRFFIDRPSTYFRPILDYLRTGQ-VPTQHIPE--VYREAQFYEIKPLV 119
                 +  D  G + IDR  TYF PIL+YLR G+ + T+ + E  V  EA+FY I  LV
Sbjct: 105 EDPELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEGVLEEAEFYNIASLV 164

Query: 120 KLLED 124
           +L+++
Sbjct: 165 RLVKE 169


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 40/132 (30%), Positives = 72/132 (54%), Gaps = 14/132 (10%)

Query: 7   VERPVGRMTSQTPLPQS--PRPRRPTMSTV-VELNVGGEFHTTTLGTLRKFPGSKLAEMF 63
           + RP+   +  +PL     P P + T S   V ++VGG  +T++L TL K+P S++  +F
Sbjct: 609 MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 668

Query: 64  SSLAKASTDA-EGRFFIDRPSTYFRPILDYLRTGQVPTQHIPE-------VYREAQFYEI 115
                   D+ +  +FIDR    FR IL++LRT ++    IP+       +Y EA+++++
Sbjct: 669 DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKL---LIPDDFKDYTLLYEEAKYFQL 725

Query: 116 KPLVKLLEDMPQ 127
           +P++  +E   Q
Sbjct: 726 QPMLLEMERWKQ 737


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 40/132 (30%), Positives = 72/132 (54%), Gaps = 14/132 (10%)

Query: 7   VERPVGRMTSQTPLPQS--PRPRRPTMSTV-VELNVGGEFHTTTLGTLRKFPGSKLAEMF 63
           + RP+   +  +PL     P P + T S   V ++VGG  +T++L TL K+P S++  +F
Sbjct: 1   MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60

Query: 64  SSLAKASTDA-EGRFFIDRPSTYFRPILDYLRTGQVPTQHIPE-------VYREAQFYEI 115
                   D+ +  +FIDR    FR IL++LRT ++    IP+       +Y EA+++++
Sbjct: 61  DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKL---LIPDDFKDYTLLYEEAKYFQL 117

Query: 116 KPLVKLLEDMPQ 127
           +P++  +E   Q
Sbjct: 118 QPMLLEMERWKQ 129


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 40/132 (30%), Positives = 72/132 (54%), Gaps = 14/132 (10%)

Query: 7   VERPVGRMTSQTPLPQS--PRPRRPTMSTV-VELNVGGEFHTTTLGTLRKFPGSKLAEMF 63
           + RP+   +  +PL     P P + T S   V ++VGG  +T++L TL K+P S++  +F
Sbjct: 1   MSRPLITRSPASPLNNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPESRIGRLF 60

Query: 64  SSLAKASTDA-EGRFFIDRPSTYFRPILDYLRTGQVPTQHIPE-------VYREAQFYEI 115
                   D+ +  +FIDR    FR IL++LRT ++    IP+       +Y EA+++++
Sbjct: 61  DGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKL---LIPDDFKDYTLLYEEAKYFQL 117

Query: 116 KPLVKLLEDMPQ 127
           +P++  +E   Q
Sbjct: 118 QPMLLEMERWKQ 129


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 34/96 (35%), Positives = 55/96 (57%), Gaps = 10/96 (10%)

Query: 32  STVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILD 91
           ST++ LNVGG  + T   TL K+P + L  + +       DA+G +FIDR    FR +L+
Sbjct: 32  STLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLN 91

Query: 92  YLRTGQVPTQHIPEVYR-------EAQFYEIKPLVK 120
           +LR G++    +PE +R       EA+F+++K L +
Sbjct: 92  FLRNGEL---LLPEGFRENQLLAQEAEFFQLKGLAE 124


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 35/91 (38%), Positives = 49/91 (53%), Gaps = 2/91 (2%)

Query: 34  VVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYL 93
           +V+LNVGG   +T+  TL   P S  + + S       D  G  FIDR    F PIL++L
Sbjct: 19  IVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFL 78

Query: 94  RTGQVPTQ--HIPEVYREAQFYEIKPLVKLL 122
           RT ++  +   I  +  EA+FY I PLV+ L
Sbjct: 79  RTKELDLRGVSINVLRHEAEFYGITPLVRRL 109


>gi|169184031 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 47/125 (37%), Positives = 61/125 (48%), Gaps = 14/125 (11%)

Query: 37  LNVGGEFHTTTLGTL-RKFPGSKLAEMFSSLAKAST--DAEGRFFIDRPSTYFRPILDYL 93
           L+VGG++ TTT  TL  K P   LA MF          D  G F ID+   YF PIL+YL
Sbjct: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPILNYL 152

Query: 94  RTGQVPTQ---HIPEVYREAQFYEIKPLVKLLE-----DMPQIFGEQVSRKQF---LLQV 142
           R GQ+       +  V  EA+F+ I  L++ L+       P      +SRK+F   LL  
Sbjct: 153 RHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQPPEDHLPISRKEFVRCLLAT 212

Query: 143 PGYSE 147
           P  SE
Sbjct: 213 PTKSE 217


>gi|169179790 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 47/125 (37%), Positives = 61/125 (48%), Gaps = 14/125 (11%)

Query: 37  LNVGGEFHTTTLGTL-RKFPGSKLAEMFSSLAKAST--DAEGRFFIDRPSTYFRPILDYL 93
           L+VGG++ TTT  TL  K P   LA MF          D  G F ID+   YF PIL+YL
Sbjct: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPILNYL 152

Query: 94  RTGQVPTQ---HIPEVYREAQFYEIKPLVKLLE-----DMPQIFGEQVSRKQF---LLQV 142
           R GQ+       +  V  EA+F+ I  L++ L+       P      +SRK+F   LL  
Sbjct: 153 RHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQPPEDHLPISRKEFVRCLLAT 212

Query: 143 PGYSE 147
           P  SE
Sbjct: 213 PTKSE 217


>gi|169180181 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 47/125 (37%), Positives = 61/125 (48%), Gaps = 14/125 (11%)

Query: 37  LNVGGEFHTTTLGTL-RKFPGSKLAEMFSSLAKAST--DAEGRFFIDRPSTYFRPILDYL 93
           L+VGG++ TTT  TL  K P   LA MF          D  G F ID+   YF PIL+YL
Sbjct: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPILNYL 152

Query: 94  RTGQVPTQ---HIPEVYREAQFYEIKPLVKLLE-----DMPQIFGEQVSRKQF---LLQV 142
           R GQ+       +  V  EA+F+ I  L++ L+       P      +SRK+F   LL  
Sbjct: 153 RHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQPPEDHLPISRKEFVRCLLAT 212

Query: 143 PGYSE 147
           P  SE
Sbjct: 213 PTKSE 217


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 37/94 (39%), Positives = 54/94 (57%), Gaps = 4/94 (4%)

Query: 35  VELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLA-KASTDAEGRFFIDRPSTYFRPILDYL 93
           V LNVGG    TT  TL +   S L+ +      ++  D  G + IDR  TYF PIL++L
Sbjct: 33  VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92

Query: 94  RTGQ-VPTQHIPE--VYREAQFYEIKPLVKLLED 124
           R G+ V  + + E  V  EA+FY I PL+++++D
Sbjct: 93  RHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKD 126


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 5/97 (5%)

Query: 35  VELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYLR 94
           V+LNVGG  + TT+  L +   + L  MFS   +  TD EG   IDR   +F  IL+YLR
Sbjct: 30  VQLNVGGSLYYTTVRALTRHD-TMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88

Query: 95  TGQVP----TQHIPEVYREAQFYEIKPLVKLLEDMPQ 127
              +      Q I E+  EA++Y I+ LV + +   Q
Sbjct: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQ 125


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 32/85 (37%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 34  VVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYL 93
           V+ LNVGG  +T    +L +F  S LA MFS      TD  G   IDR    F+ +LDYL
Sbjct: 13  VLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDYL 72

Query: 94  R-TGQVPTQHIPEV--YREAQFYEI 115
               Q+PT     +    EA ++ I
Sbjct: 73  HGEVQIPTDEQTRIALQEEADYFGI 97


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,410,568
Number of Sequences: 37866
Number of extensions: 404590
Number of successful extensions: 1183
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 1076
Number of HSP's gapped (non-prelim): 75
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.