Guide to the Human Genome
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Search of human proteins with 14165276

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14165276 esophageal cancer related gene 4 protein [Homo
sapiens]
         (148 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14165276 esophageal cancer related gene 4 protein [Homo sapiens]   314   2e-86
gi|4502713 CDC45-like [Homo sapiens]                                   32   0.25 
gi|21361837 chromosome 1 open reading frame 128 [Homo sapiens]         32   0.25 
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ...    31   0.43 
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ...    31   0.43 
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ...    31   0.43 
gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]                30   0.96 
gi|46488923 astrotactin isoform 1 [Homo sapiens]                       28   2.8  
gi|46488921 astrotactin isoform 2 [Homo sapiens]                       28   2.8  
gi|239754588 PREDICTED: similar to SLC29A4 protein [Homo sapiens]      28   2.8  
gi|239743194 PREDICTED: similar to SLC29A4 protein [Homo sapiens]      28   3.7  
gi|239743171 PREDICTED: hypothetical protein XP_002342767 [Homo ...    28   3.7  
gi|239508863 PREDICTED: similar to SLC29A4 protein [Homo sapiens]      28   3.7  
gi|239508835 PREDICTED: similar to SLC29A4 protein [Homo sapiens]      28   3.7  
gi|133893286 acidic chitinase isoform c [Homo sapiens]                 27   4.8  
gi|42542398 acidic chitinase isoform a [Homo sapiens]                  27   4.8  
gi|4826708 ephrin A3 [Homo sapiens]                                    27   6.2  
gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]         27   6.2  
gi|27477109 itchy homolog E3 ubiquitin protein ligase [Homo sapi...    27   6.2  
gi|71040111 fibromodulin precursor [Homo sapiens]                      27   6.2  
gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens]         27   6.2  
gi|41054804 hypothetical protein LOC84970 isoform b [Homo sapiens]     27   6.2  
gi|197927133 hypothetical protein LOC84970 isoform a [Homo sapiens]    27   6.2  
gi|19923599 calmin [Homo sapiens]                                      27   6.2  
gi|31581524 cordon-bleu homolog [Homo sapiens]                         27   8.2  

>gi|14165276 esophageal cancer related gene 4 protein [Homo sapiens]
          Length = 148

 Score =  314 bits (805), Expect = 2e-86
 Identities = 148/148 (100%), Positives = 148/148 (100%)

Query: 1   MAASPARPAVLALTGLALLLLLCWGPGGISGNKLKLMLQKREAPVPTKTKVAVDENKAKE 60
           MAASPARPAVLALTGLALLLLLCWGPGGISGNKLKLMLQKREAPVPTKTKVAVDENKAKE
Sbjct: 1   MAASPARPAVLALTGLALLLLLCWGPGGISGNKLKLMLQKREAPVPTKTKVAVDENKAKE 60

Query: 61  FLGSLKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNGHEYYGDYYQ 120
           FLGSLKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNGHEYYGDYYQ
Sbjct: 61  FLGSLKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNGHEYYGDYYQ 120

Query: 121 RHYDEDSAIGPRSPYGFRHGASVNYDDY 148
           RHYDEDSAIGPRSPYGFRHGASVNYDDY
Sbjct: 121 RHYDEDSAIGPRSPYGFRHGASVNYDDY 148


>gi|4502713 CDC45-like [Homo sapiens]
          Length = 566

 Score = 31.6 bits (70), Expect = 0.25
 Identities = 14/65 (21%), Positives = 37/65 (56%), Gaps = 3/65 (4%)

Query: 46  PTKTKVAVDENKAKEFLGSLKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWL 105
           P++ +  ++E   ++   +++R++R+ W+  R ++   Y+Q+ Y G   A    ++ + L
Sbjct: 153 PSEKRTRLEEEIVEQ---TMRRRQRREWEARRRDILFDYEQYEYHGTSSAMVMFELAWML 209

Query: 106 NRDRN 110
           ++D N
Sbjct: 210 SKDLN 214


>gi|21361837 chromosome 1 open reading frame 128 [Homo sapiens]
          Length = 211

 Score = 31.6 bits (70), Expect = 0.25
 Identities = 16/48 (33%), Positives = 22/48 (45%)

Query: 74  DRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNGHEYYGDYYQR 121
           D + P   + Y+    M FD+ + E D T+ LNRD  G   Y     R
Sbjct: 98  DDSHPSEMRLYKNIPQMSFDDTEREPDQTFSLNRDLTGELEYATKISR 145


>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
           [Homo sapiens]
          Length = 543

 Score = 30.8 bits (68), Expect = 0.43
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 52  AVDENKAKEFLGSLKRQKRQLWD--RTRPE-VQQWYQQFLYMGFDEAKFEDDITYWLNRD 108
           A ++N   +F  + +  KR+  D  +T PE VQ+ Y+ F     DE K E++     N D
Sbjct: 443 ASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEKMCNSD 502

Query: 109 RNGHEYYGDYYQRHYDEDSAIGP 131
            +      D  Q+H + ++ + P
Sbjct: 503 NSSTAMLTDCIQQHAELENGMIP 525


>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
           [Homo sapiens]
          Length = 543

 Score = 30.8 bits (68), Expect = 0.43
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 52  AVDENKAKEFLGSLKRQKRQLWD--RTRPE-VQQWYQQFLYMGFDEAKFEDDITYWLNRD 108
           A ++N   +F  + +  KR+  D  +T PE VQ+ Y+ F     DE K E++     N D
Sbjct: 443 ASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEKMCNSD 502

Query: 109 RNGHEYYGDYYQRHYDEDSAIGP 131
            +      D  Q+H + ++ + P
Sbjct: 503 NSSTAMLTDCIQQHAELENGMIP 525


>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
           [Homo sapiens]
          Length = 538

 Score = 30.8 bits (68), Expect = 0.43
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 52  AVDENKAKEFLGSLKRQKRQLWD--RTRPE-VQQWYQQFLYMGFDEAKFEDDITYWLNRD 108
           A ++N   +F  + +  KR+  D  +T PE VQ+ Y+ F     DE K E++     N D
Sbjct: 438 ASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEKMCNSD 497

Query: 109 RNGHEYYGDYYQRHYDEDSAIGP 131
            +      D  Q+H + ++ + P
Sbjct: 498 NSSTAMLTDCIQQHAELENGMIP 520


>gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]
          Length = 690

 Score = 29.6 bits (65), Expect = 0.96
 Identities = 20/84 (23%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 4   SPARPAVLALTGLALLLLLCWGPGGISGNK-LKLMLQKREAPVPTKTKVAVDENKAKEFL 62
           SP  P      G   + +L WG  G++G   L+  +Q+  +      K+   +N     L
Sbjct: 294 SPTPPQQFQPAGTDQVCVLEWGAEGVAGKSGLEKEVQRLTSRAARDYKI---QNHGHRVL 350

Query: 63  GSLKRQKRQLWDRTRPEVQQWYQQ 86
             L+++++Q  +R  P ++Q  Q+
Sbjct: 351 QRLEQRRQQASEREAPSIEQRLQE 374


>gi|46488923 astrotactin isoform 1 [Homo sapiens]
          Length = 1294

 Score = 28.1 bits (61), Expect = 2.8
 Identities = 10/19 (52%), Positives = 12/19 (63%)

Query: 11 LALTGLALLLLLCWGPGGI 29
          +AL GL  LL  CWGP  +
Sbjct: 1  MALAGLCALLACCWGPAAV 19


>gi|46488921 astrotactin isoform 2 [Homo sapiens]
          Length = 1216

 Score = 28.1 bits (61), Expect = 2.8
 Identities = 10/19 (52%), Positives = 12/19 (63%)

Query: 11 LALTGLALLLLLCWGPGGI 29
          +AL GL  LL  CWGP  +
Sbjct: 1  MALAGLCALLACCWGPAAV 19


>gi|239754588 PREDICTED: similar to SLC29A4 protein [Homo sapiens]
          Length = 193

 Score = 28.1 bits (61), Expect = 2.8
 Identities = 12/30 (40%), Positives = 19/30 (63%)

Query: 21  LLCWGPGGISGNKLKLMLQKREAPVPTKTK 50
           +L  GPG  +G+K K   Q RE P+P+ ++
Sbjct: 160 VLVGGPGKEAGDKAKEQQQSRERPIPSPSE 189


>gi|239743194 PREDICTED: similar to SLC29A4 protein [Homo sapiens]
          Length = 307

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 12/27 (44%), Positives = 17/27 (62%)

Query: 21  LLCWGPGGISGNKLKLMLQKREAPVPT 47
           +L  GPG  +G+K K   Q RE P+P+
Sbjct: 211 VLVGGPGKEAGDKAKEQQQSRERPIPS 237


>gi|239743171 PREDICTED: hypothetical protein XP_002342767 [Homo
           sapiens]
          Length = 307

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 12/27 (44%), Positives = 17/27 (62%)

Query: 21  LLCWGPGGISGNKLKLMLQKREAPVPT 47
           +L  GPG  +G+K K   Q RE P+P+
Sbjct: 211 VLVGGPGKEAGDKAKEQQQSRERPIPS 237


>gi|239508863 PREDICTED: similar to SLC29A4 protein [Homo sapiens]
          Length = 307

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 12/27 (44%), Positives = 17/27 (62%)

Query: 21  LLCWGPGGISGNKLKLMLQKREAPVPT 47
           +L  GPG  +G+K K   Q RE P+P+
Sbjct: 211 VLVGGPGKEAGDKAKEQQQSRERPIPS 237


>gi|239508835 PREDICTED: similar to SLC29A4 protein [Homo sapiens]
          Length = 307

 Score = 27.7 bits (60), Expect = 3.7
 Identities = 12/27 (44%), Positives = 17/27 (62%)

Query: 21  LLCWGPGGISGNKLKLMLQKREAPVPT 47
           +L  GPG  +G+K K   Q RE P+P+
Sbjct: 211 VLVGGPGKEAGDKAKEQQQSRERPIPS 237


>gi|133893286 acidic chitinase isoform c [Homo sapiens]
          Length = 476

 Score = 27.3 bits (59), Expect = 4.8
 Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 65  LKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNG 111
           LK    Q WD  + EV   YQ  +++G+D  K  D    WL  ++ G
Sbjct: 310 LKNGATQGWDAPQ-EVPYAYQGNVWVGYDNIKSFDIKAQWLKHNKFG 355


>gi|42542398 acidic chitinase isoform a [Homo sapiens]
          Length = 368

 Score = 27.3 bits (59), Expect = 4.8
 Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 1/47 (2%)

Query: 65  LKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNG 111
           LK    Q WD  + EV   YQ  +++G+D  K  D    WL  ++ G
Sbjct: 202 LKNGATQGWDAPQ-EVPYAYQGNVWVGYDNIKSFDIKAQWLKHNKFG 247


>gi|4826708 ephrin A3 [Homo sapiens]
          Length = 238

 Score = 26.9 bits (58), Expect = 6.2
 Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 1/33 (3%)

Query: 1  MAASPARPAVLALTGLALLLLLCWGPGGISGNK 33
          MAA+P    +L L  + LL LL  GPGG  GN+
Sbjct: 1  MAAAPLL-LLLLLVPVPLLPLLAQGPGGALGNR 32


>gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]
          Length = 728

 Score = 26.9 bits (58), Expect = 6.2
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 1/47 (2%)

Query: 34  LKLMLQKREAPVPTKTKVAVDENKAKEFLGSL-KRQKRQLWDRTRPE 79
           L++ LQ  EA         + E +A+E L  + K  + QLW R RPE
Sbjct: 670 LQVKLQHAEADREQLRADLLREREAREHLEKVVKELQEQLWPRARPE 716


>gi|27477109 itchy homolog E3 ubiquitin protein ligase [Homo
           sapiens]
          Length = 862

 Score = 26.9 bits (58), Expect = 6.2
 Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 8/80 (10%)

Query: 12  ALTGLALLLLLCWGPGGISGNKLKLMLQKREAPVPTKTKVAVDENKAKEFLGSLKRQKRQ 71
           A +GL + L +  G G    N +       +AP+P   +  VD++    ++  +  +KR 
Sbjct: 260 ATSGLIIPLTISGGSGPRPLNPVT------QAPLPPGWEQRVDQHGRVYYVDHV--EKRT 311

Query: 72  LWDRTRPEVQQWYQQFLYMG 91
            WDR  P    W ++   MG
Sbjct: 312 TWDRPEPLPPGWERRVDNMG 331


>gi|71040111 fibromodulin precursor [Homo sapiens]
          Length = 376

 Score = 26.9 bits (58), Expect = 6.2
 Identities = 19/67 (28%), Positives = 27/67 (40%), Gaps = 6/67 (8%)

Query: 82  QWYQQFLYMGF---DEAKFEDDITYWLNRDRNGHEYYGDYYQRHYDEDSAIGPRSPYGFR 138
           QW    L  G     +A++EDD  +W +  R+    Y D Y  +  E        PYG  
Sbjct: 2   QWTSLLLLAGLFSLSQAQYEDDPHWWFHYLRSQQSTYYDPYDPYPYETY---EPYPYGVD 58

Query: 139 HGASVNY 145
            G +  Y
Sbjct: 59  EGPAYTY 65


>gi|118197272 ATG2 autophagy related 2 homolog B [Homo sapiens]
          Length = 2078

 Score = 26.9 bits (58), Expect = 6.2
 Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 6/62 (9%)

Query: 28   GISGNKLKLMLQKREAPVPTKTKVAVDENKAKEFLGSLKRQKRQLWDRTRPEVQQWYQQF 87
            G+ G+ L ++       V  K      E+  KEFL ++  +   L  R  P    W++Q 
Sbjct: 1162 GVGGDSLNML------SVAVKILSDKSESNTKEFLIAVGLKGATLQHRMLPSGLSWHEQI 1215

Query: 88   LY 89
            LY
Sbjct: 1216 LY 1217


>gi|41054804 hypothetical protein LOC84970 isoform b [Homo sapiens]
          Length = 408

 Score = 26.9 bits (58), Expect = 6.2
 Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 13/78 (16%)

Query: 46  PTKTKVAVDENKAKEFLGSLKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWL 105
           P K     ++N   EFLG+ K    Q   R + EV             E KF   +T   
Sbjct: 193 PKKPTCPAEKNLLYEFLGATKNPSGQPRLRNKVEVDG----------PELKFNAPVTV-- 240

Query: 106 NRDRNGHEYYGDYYQRHY 123
             D+N  +Y G+ +  H+
Sbjct: 241 -ADKNNPKYTGNVFTPHF 257


>gi|197927133 hypothetical protein LOC84970 isoform a [Homo sapiens]
          Length = 598

 Score = 26.9 bits (58), Expect = 6.2
 Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 13/78 (16%)

Query: 46  PTKTKVAVDENKAKEFLGSLKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWL 105
           P K     ++N   EFLG+ K    Q   R + EV             E KF   +T   
Sbjct: 383 PKKPTCPAEKNLLYEFLGATKNPSGQPRLRNKVEVDG----------PELKFNAPVTV-- 430

Query: 106 NRDRNGHEYYGDYYQRHY 123
             D+N  +Y G+ +  H+
Sbjct: 431 -ADKNNPKYTGNVFTPHF 447


>gi|19923599 calmin [Homo sapiens]
          Length = 1002

 Score = 26.9 bits (58), Expect = 6.2
 Identities = 25/108 (23%), Positives = 44/108 (40%), Gaps = 8/108 (7%)

Query: 39  QKREAPVPTKTKVAVDENKAKEFLGSLKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAK-- 96
           Q +E+P        ++EN  KE + S K++KR+  D     +      F+  G  ++   
Sbjct: 837 QSQESPNLENIANPLEENVTKESISSKKKEKRKHVDHVESSL------FVAPGSVQSSDD 890

Query: 97  FEDDITYWLNRDRNGHEYYGDYYQRHYDEDSAIGPRSPYGFRHGASVN 144
            E+D + +    R  H     Y +RH    S     S    R+ A ++
Sbjct: 891 LEEDSSDYSIPSRTSHSDSSIYLRRHTHRSSESDHFSYVQLRNAADLD 938


>gi|31581524 cordon-bleu homolog [Homo sapiens]
          Length = 1261

 Score = 26.6 bits (57), Expect = 8.2
 Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 4/49 (8%)

Query: 27  GGISGNKLKLMLQKREAPVPTKTKVAV-DENKAKEFLGS---LKRQKRQ 71
           G ISG  +K  ++KR AP P  +   V D+   K  LGS   L+++KR+
Sbjct: 286 GSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRR 334


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,369,715
Number of Sequences: 37866
Number of extensions: 285367
Number of successful extensions: 813
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 800
Number of HSP's gapped (non-prelim): 25
length of query: 148
length of database: 18,247,518
effective HSP length: 93
effective length of query: 55
effective length of database: 14,725,980
effective search space: 809928900
effective search space used: 809928900
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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