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Search of human proteins with 9966859
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9966859 HRAS-like suppressor [Homo sapiens]
(168 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9966859 HRAS-like suppressor [Homo sapiens] 345 8e-96
gi|189571621 HRAS-like suppressor 3 [Homo sapiens] 148 2e-36
gi|189571618 HRAS-like suppressor 3 [Homo sapiens] 148 2e-36
gi|8923526 HRAS-like suppressor 2 [Homo sapiens] 143 8e-35
gi|149588791 retinoic acid receptor responder (tazarotene induce... 137 4e-33
gi|16905367 HRAS-like suppressor family, member 5 isoform 1 [Hom... 119 9e-28
gi|226491950 HRAS-like suppressor family, member 5 isoform 2 [Ho... 119 9e-28
gi|226528146 HRAS-like suppressor family, member 5 isoform 3 [Ho... 99 1e-21
gi|46249410 lecithin retinol acyltransferase [Homo sapiens] 67 6e-12
gi|28557798 family with sequence similarity 84, member B [Homo s... 42 3e-04
gi|21536485 HIR histone cell cycle regulation defective homolog ... 33 0.15
gi|133908623 protein kinase C, iota [Homo sapiens] 30 0.97
gi|52486327 protein kinase C, zeta isoform 1 [Homo sapiens] 30 1.3
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 29 1.7
gi|21553329 family with sequence similarity 84, member A [Homo s... 28 4.8
gi|29029559 CSE1 chromosome segregation 1-like protein [Homo sap... 27 6.3
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H... 27 6.3
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H... 27 6.3
gi|22024390 potassium voltage-gated channel, subfamily H, member... 27 8.3
gi|27886648 potassium voltage-gated channel, subfamily H, member... 27 8.3
gi|27886646 potassium voltage-gated channel, subfamily H, member... 27 8.3
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 27 8.3
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 27 8.3
>gi|9966859 HRAS-like suppressor [Homo sapiens]
Length = 168
Score = 345 bits (886), Expect = 8e-96
Identities = 168/168 (100%), Positives = 168/168 (100%)
Query: 1 MAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIPASFTSAKSVF 60
MAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIPASFTSAKSVF
Sbjct: 1 MAFNDCFSLNYPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIPASFTSAKSVF 60
Query: 61 SSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCE 120
SSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCE
Sbjct: 61 SSKALVKMQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCE 120
Query: 121 HFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLGLFPKGQRAKYY 168
HFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLGLFPKGQRAKYY
Sbjct: 121 HFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLGLFPKGQRAKYY 168
>gi|189571621 HRAS-like suppressor 3 [Homo sapiens]
Length = 162
Score = 148 bits (374), Expect = 2e-36
Identities = 72/154 (46%), Positives = 99/154 (64%), Gaps = 2/154 (1%)
Query: 15 PCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIP-ASFTSAKSVFSSKALVKMQLLKD 73
P PGDLIE+FRP Y+HWA+Y+GDGYV+++AP + A S S + KA+VK +LL D
Sbjct: 8 PKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELLYD 67
Query: 74 VVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGEGVS 133
V G+D Y++NNK+D+ Y PLP +II+R+E ++GQEV Y L NCEHFV LRYG S
Sbjct: 68 VAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNELRYGVARS 127
Query: 134 EQANRAISTVEFVTAAVGVFSFLG-LFPKGQRAK 166
+Q I + S +G +F + +R K
Sbjct: 128 DQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQK 161
>gi|189571618 HRAS-like suppressor 3 [Homo sapiens]
Length = 162
Score = 148 bits (374), Expect = 2e-36
Identities = 72/154 (46%), Positives = 99/154 (64%), Gaps = 2/154 (1%)
Query: 15 PCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIP-ASFTSAKSVFSSKALVKMQLLKD 73
P PGDLIE+FRP Y+HWA+Y+GDGYV+++AP + A S S + KA+VK +LL D
Sbjct: 8 PKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELLYD 67
Query: 74 VVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGEGVS 133
V G+D Y++NNK+D+ Y PLP +II+R+E ++GQEV Y L NCEHFV LRYG S
Sbjct: 68 VAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNELRYGVARS 127
Query: 134 EQANRAISTVEFVTAAVGVFSFLG-LFPKGQRAK 166
+Q I + S +G +F + +R K
Sbjct: 128 DQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQK 161
>gi|8923526 HRAS-like suppressor 2 [Homo sapiens]
Length = 162
Score = 143 bits (360), Expect = 8e-35
Identities = 69/145 (47%), Positives = 96/145 (66%), Gaps = 1/145 (0%)
Query: 15 PCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIP-ASFTSAKSVFSSKALVKMQLLKD 73
P GDLIE+ R GY HWA+Y+GDGYV+++AP I A S S ++KA+VK +LL
Sbjct: 8 PRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSV 67
Query: 74 VVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGEGVS 133
V G D YR+NNK+D+ Y PLP +I+KR+E ++GQE+ Y+L +NCEHFV LRYG S
Sbjct: 68 VAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRS 127
Query: 134 EQANRAISTVEFVTAAVGVFSFLGL 158
+Q A++TV + S +G+
Sbjct: 128 DQVTGAVTTVGVAAGLLAAASLVGI 152
>gi|149588791 retinoic acid receptor responder (tazarotene induced)
3 [Homo sapiens]
Length = 164
Score = 137 bits (345), Expect = 4e-33
Identities = 69/135 (51%), Positives = 91/135 (67%), Gaps = 1/135 (0%)
Query: 15 PCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIP-ASFTSAKSVFSSKALVKMQLLKD 73
P PGDLIE+FR GY+HWALY+GDGYVI++AP P A +S SV S+ A VK + L+D
Sbjct: 8 PKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEVKRERLED 67
Query: 74 VVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGEGVS 133
VVG YR+NN D Y P PVE II ++ ++GQ++ Y+++ NCEHFVT LRYG+
Sbjct: 68 VVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQLRYGKSRC 127
Query: 134 EQANRAISTVEFVTA 148
+Q +A V TA
Sbjct: 128 KQVEKAKVEVGVATA 142
>gi|16905367 HRAS-like suppressor family, member 5 isoform 1 [Homo
sapiens]
Length = 279
Score = 119 bits (299), Expect = 9e-28
Identities = 63/140 (45%), Positives = 93/140 (66%), Gaps = 3/140 (2%)
Query: 15 PCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIPASFTSAKSVFSSKALVKMQLLKDV 74
P PGDLIE+FR GY+HWA+Y+ D V+++AP S S+FS++A+VK L+DV
Sbjct: 130 PRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSE-EFEVGSITSIFSNRAVVKYSRLEDV 188
Query: 75 VGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGEGVSE 134
+ ++++NNK D TY PLPV++II+R++ ++ + V Y+L+ NCEHFV LRYG S+
Sbjct: 189 LHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVNGLRYGVPRSQ 248
Query: 135 QANRAISTVEFVTAAVGVFS 154
Q A+ +E AA V S
Sbjct: 249 QVEHAL--MEGAKAAGAVIS 266
>gi|226491950 HRAS-like suppressor family, member 5 isoform 2 [Homo
sapiens]
Length = 269
Score = 119 bits (299), Expect = 9e-28
Identities = 63/140 (45%), Positives = 93/140 (66%), Gaps = 3/140 (2%)
Query: 15 PCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIPASFTSAKSVFSSKALVKMQLLKDV 74
P PGDLIE+FR GY+HWA+Y+ D V+++AP S S+FS++A+VK L+DV
Sbjct: 120 PRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSE-EFEVGSITSIFSNRAVVKYSRLEDV 178
Query: 75 VGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGEGVSE 134
+ ++++NNK D TY PLPV++II+R++ ++ + V Y+L+ NCEHFV LRYG S+
Sbjct: 179 LHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVNGLRYGVPRSQ 238
Query: 135 QANRAISTVEFVTAAVGVFS 154
Q A+ +E AA V S
Sbjct: 239 QVEHAL--MEGAKAAGAVIS 256
>gi|226528146 HRAS-like suppressor family, member 5 isoform 3 [Homo
sapiens]
Length = 253
Score = 99.4 bits (246), Expect = 1e-21
Identities = 47/105 (44%), Positives = 74/105 (70%), Gaps = 1/105 (0%)
Query: 15 PCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIPASFTSAKSVFSSKALVKMQLLKDV 74
P PGDLIE+FR GY+HWA+Y+ D V+++AP S S+FS++A+VK L+DV
Sbjct: 130 PRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSE-EFEVGSITSIFSNRAVVKYSRLEDV 188
Query: 75 VGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNC 119
+ ++++NNK D TY PLPV++II+R++ ++ + V Y+L+ NC
Sbjct: 189 LHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNC 233
>gi|46249410 lecithin retinol acyltransferase [Homo sapiens]
Length = 230
Score = 67.4 bits (163), Expect = 6e-12
Identities = 47/142 (33%), Positives = 75/142 (52%), Gaps = 14/142 (9%)
Query: 18 GDLIEVFRPGYQHWALYLGDGYVINIAP--VDGIPASFTSAKSVFSSKALVKMQLLK--- 72
GD++EV R H+ +YLGD V ++ P + + + V S+K L+ ++K
Sbjct: 48 GDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVAS 107
Query: 73 ---DVVGNDTYRIN---NKYDETYPPLPV--EEIIKRSEFVIGQEVAYNLLVNNCEHFVT 124
D V + Y N N DE+ + EE+ +R+E ++G Y+LL NNCEHFVT
Sbjct: 108 IRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGF-TPYSLLWNNCEHFVT 166
Query: 125 LLRYGEGVSEQANRAISTVEFV 146
RYG +S Q+++ TV+ +
Sbjct: 167 YCRYGTPISPQSDKFCETVKII 188
>gi|28557798 family with sequence similarity 84, member B [Homo
sapiens]
Length = 310
Score = 41.6 bits (96), Expect = 3e-04
Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 22/119 (18%)
Query: 14 NPC-PGDLIE-VFRPGYQHWALYLGDGYVINIAPVDGIPASFTSAKSVFSSKALVKMQLL 71
N C PGDL+E V + Y HWA+Y+G+ V+++ ++ I + T A Q
Sbjct: 114 NKCKPGDLVEFVSQAQYPHWAVYVGNFQVVHLHRLEVINSFLTDAS-----------QGR 162
Query: 72 KDVVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGE 130
+ V ND YR Y PL +++ + +G + L N E F RYG+
Sbjct: 163 RGRVVNDLYR--------YKPLSSSAVVRNALAHVGAK-ERELSWRNSESFAAWCRYGK 212
>gi|21536485 HIR histone cell cycle regulation defective homolog A
[Homo sapiens]
Length = 1017
Score = 32.7 bits (73), Expect = 0.15
Identities = 16/59 (27%), Positives = 31/59 (52%)
Query: 69 QLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCEHFVTLLR 127
++ KD++G Y ++++ T L E++K VIGQ + + L C+ + +LR
Sbjct: 957 EICKDLLGPVHYSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILR 1015
>gi|133908623 protein kinase C, iota [Homo sapiens]
Length = 596
Score = 30.0 bits (66), Expect = 0.97
Identities = 12/29 (41%), Positives = 18/29 (62%), Gaps = 1/29 (3%)
Query: 12 PGNPCPGDLIEVFRPGYQHW-ALYLGDGY 39
PG PCPG+ ++R G + W LY +G+
Sbjct: 113 PGMPCPGEDKSIYRRGARRWRKLYCANGH 141
>gi|52486327 protein kinase C, zeta isoform 1 [Homo sapiens]
Length = 592
Score = 29.6 bits (65), Expect = 1.3
Identities = 12/30 (40%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 12 PGNPCPGDLIEVFRPGYQHW-ALYLGDGYV 40
PG PCPG+ ++R G + W LY +G++
Sbjct: 103 PGLPCPGEDKSIYRRGARRWRKLYRANGHL 132
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 29.3 bits (64), Expect = 1.7
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 17/92 (18%)
Query: 37 DGYVINIAPVDGIPASFTSAKSVFSSKALVKMQLLKDVVGNDTYRINNKYDETYPP--LP 94
D Y++ I DG FSSKA+V++++L D N Y +T P LP
Sbjct: 2990 DNYLLTITATDG----------TFSSKAIVEVKVL-DANDNSPVCEKTLYSDTIPEDVLP 3038
Query: 95 VEEIIKRS----EFVIGQEVAYNLLVNNCEHF 122
+ I++ S + E+ Y LL + E F
Sbjct: 3039 GKLIMQISATDADIRSNAEITYTLLGSGAEKF 3070
>gi|21553329 family with sequence similarity 84, member A [Homo
sapiens]
Length = 292
Score = 27.7 bits (60), Expect = 4.8
Identities = 13/35 (37%), Positives = 22/35 (62%), Gaps = 8/35 (22%)
Query: 17 PGDLIEVF--RPGYQ------HWALYLGDGYVINI 43
PGDL+E+ +P + HWA+Y+G G +I++
Sbjct: 122 PGDLLELLWLQPAPEPPAPAPHWAVYVGGGQIIHL 156
>gi|29029559 CSE1 chromosome segregation 1-like protein [Homo
sapiens]
Length = 971
Score = 27.3 bits (59), Expect = 6.3
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Query: 68 MQLLKDVVGNDTYRINNKYDETYPPLPVEEIIKRSEFVI--GQEVAYNLLVNNCEHFV 123
++LLK + ++ KYDE + + ++ GQEV Y+LLV+N F+
Sbjct: 264 LELLKSQICDNAALYAQKYDEEFQRYLPRFVTAIWNLLVTTGQEVKYDLLVSNAIQFL 321
>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
sapiens]
Length = 532
Score = 27.3 bits (59), Expect = 6.3
Identities = 14/41 (34%), Positives = 20/41 (48%)
Query: 80 YRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCE 120
YR+N K E Y PV+ I S +I V Y ++ N +
Sbjct: 436 YRMNQKLWEVYSGHPVQHISFSSHSLITANVPYQTVMRNAD 476
>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
sapiens]
Length = 598
Score = 27.3 bits (59), Expect = 6.3
Identities = 14/41 (34%), Positives = 20/41 (48%)
Query: 80 YRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCE 120
YR+N K E Y PV+ I S +I V Y ++ N +
Sbjct: 502 YRMNQKLWEVYSGHPVQHISFSSHSLITANVPYQTVMRNAD 542
>gi|22024390 potassium voltage-gated channel, subfamily H, member 5
isoform 1 [Homo sapiens]
Length = 988
Score = 26.9 bits (58), Expect = 8.3
Identities = 14/54 (25%), Positives = 27/54 (50%)
Query: 112 YNLLVNNCEHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLGLFPKGQRA 165
Y+ ++NN F+ L + +G+SE+ I + ++ + L + PK RA
Sbjct: 481 YHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRA 534
>gi|27886648 potassium voltage-gated channel, subfamily H, member 5
isoform 2 [Homo sapiens]
Length = 624
Score = 26.9 bits (58), Expect = 8.3
Identities = 14/54 (25%), Positives = 27/54 (50%)
Query: 112 YNLLVNNCEHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLGLFPKGQRA 165
Y+ ++NN F+ L + +G+SE+ I + ++ + L + PK RA
Sbjct: 423 YHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRA 476
>gi|27886646 potassium voltage-gated channel, subfamily H, member 5
isoform 3 [Homo sapiens]
Length = 611
Score = 26.9 bits (58), Expect = 8.3
Identities = 14/54 (25%), Positives = 27/54 (50%)
Query: 112 YNLLVNNCEHFVTLLRYGEGVSEQANRAISTVEFVTAAVGVFSFLGLFPKGQRA 165
Y+ ++NN F+ L + +G+SE+ I + ++ + L + PK RA
Sbjct: 481 YHEMLNNVRDFLKLYQVPKGLSERVMDYIVSTWSMSKGIDTEKVLSICPKDMRA 534
>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
Length = 3859
Score = 26.9 bits (58), Expect = 8.3
Identities = 14/48 (29%), Positives = 21/48 (43%)
Query: 11 YPGNPCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIPASFTSAKS 58
+P P ++ V G + GDG V+ + P D + TSA S
Sbjct: 2545 FPVTPADSSVVPVTPAGVPVVPVTPGDGPVVPVTPADSLVVPVTSADS 2592
>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo
sapiens]
Length = 795
Score = 26.9 bits (58), Expect = 8.3
Identities = 9/33 (27%), Positives = 19/33 (57%)
Query: 96 EEIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRY 128
+ + + ++GQEV Y++ +C T+L+Y
Sbjct: 203 QRVADEMDVMLGQEVGYSIRFEDCSSAKTILKY 235
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.140 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,388,477
Number of Sequences: 37866
Number of extensions: 259066
Number of successful extensions: 521
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 490
Number of HSP's gapped (non-prelim): 27
length of query: 168
length of database: 18,247,518
effective HSP length: 95
effective length of query: 73
effective length of database: 14,650,248
effective search space: 1069468104
effective search space used: 1069468104
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.