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Search of human proteins with 96975038
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|96975038 coiled-coil domain containing 100 [Homo sapiens]
(986 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|96975038 coiled-coil domain containing 100 [Homo sapiens] 1942 0.0
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 82 2e-15
gi|148746195 trichohyalin [Homo sapiens] 79 2e-14
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 75 3e-13
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 75 4e-13
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 75 4e-13
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 74 9e-13
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 71 4e-12
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 71 6e-12
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 71 6e-12
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 71 6e-12
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 71 6e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 71 6e-12
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 70 7e-12
gi|34878777 ring finger protein 20 [Homo sapiens] 70 7e-12
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 70 7e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 70 1e-11
gi|55770834 centromere protein F [Homo sapiens] 70 1e-11
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 70 1e-11
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 69 2e-11
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 69 2e-11
gi|221139761 zinc finger protein 853 [Homo sapiens] 69 2e-11
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 69 2e-11
gi|71061468 centromere protein E [Homo sapiens] 69 2e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 69 3e-11
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 69 3e-11
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 67 8e-11
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 67 8e-11
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 67 1e-10
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 66 1e-10
>gi|96975038 coiled-coil domain containing 100 [Homo sapiens]
Length = 986
Score = 1942 bits (5032), Expect = 0.0
Identities = 986/986 (100%), Positives = 986/986 (100%)
Query: 1 MVSKSDQLLIVVSILEGRHFPKRPKHMLVVEAKFDGEQLATDPVDHTDQPEFATELAWEI 60
MVSKSDQLLIVVSILEGRHFPKRPKHMLVVEAKFDGEQLATDPVDHTDQPEFATELAWEI
Sbjct: 1 MVSKSDQLLIVVSILEGRHFPKRPKHMLVVEAKFDGEQLATDPVDHTDQPEFATELAWEI 60
Query: 61 DRKALHQHRLQRTPIKLQCFALDPVTSAKETIGYIVLDLRTAQETKQAPKWYQLLSNKYT 120
DRKALHQHRLQRTPIKLQCFALDPVTSAKETIGYIVLDLRTAQETKQAPKWYQLLSNKYT
Sbjct: 61 DRKALHQHRLQRTPIKLQCFALDPVTSAKETIGYIVLDLRTAQETKQAPKWYQLLSNKYT 120
Query: 121 KFKSEIQISIALETDTKPPVDSFKAKGAPPRDGKVPAILAGLDPRDIVAVLNEEGGYHQI 180
KFKSEIQISIALETDTKPPVDSFKAKGAPPRDGKVPAILAGLDPRDIVAVLNEEGGYHQI
Sbjct: 121 KFKSEIQISIALETDTKPPVDSFKAKGAPPRDGKVPAILAGLDPRDIVAVLNEEGGYHQI 180
Query: 181 GPAEYCTDSFIMSVTIAFATQLEQLIPCTMKLPERQPEFFFYYSLLGNDVTNEPFNDLIN 240
GPAEYCTDSFIMSVTIAFATQLEQLIPCTMKLPERQPEFFFYYSLLGNDVTNEPFNDLIN
Sbjct: 181 GPAEYCTDSFIMSVTIAFATQLEQLIPCTMKLPERQPEFFFYYSLLGNDVTNEPFNDLIN 240
Query: 241 PNFEPERASVRIRSSVEILRVYLALQSKLQIHLCCGDQSLGSTEIPLTGLLKKGSTEINQ 300
PNFEPERASVRIRSSVEILRVYLALQSKLQIHLCCGDQSLGSTEIPLTGLLKKGSTEINQ
Sbjct: 241 PNFEPERASVRIRSSVEILRVYLALQSKLQIHLCCGDQSLGSTEIPLTGLLKKGSTEINQ 300
Query: 301 HPVTVEGAFTLDPPNRAKQKLAPIPVELAPTVGVSVALQREGIDSQSLIELKTQNEHEPE 360
HPVTVEGAFTLDPPNRAKQKLAPIPVELAPTVGVSVALQREGIDSQSLIELKTQNEHEPE
Sbjct: 301 HPVTVEGAFTLDPPNRAKQKLAPIPVELAPTVGVSVALQREGIDSQSLIELKTQNEHEPE 360
Query: 361 HSKKKVLTPIKEKTLTGPKSPTVSPVPSHNQSPPTKDDATESEVESLQYDKDTKPNPKAS 420
HSKKKVLTPIKEKTLTGPKSPTVSPVPSHNQSPPTKDDATESEVESLQYDKDTKPNPKAS
Sbjct: 361 HSKKKVLTPIKEKTLTGPKSPTVSPVPSHNQSPPTKDDATESEVESLQYDKDTKPNPKAS 420
Query: 421 SSVPASLAQLVTTSNASEVASGQKIAVPATSHHFCFSIDLRSIHALEIGFPINCILRYSY 480
SSVPASLAQLVTTSNASEVASGQKIAVPATSHHFCFSIDLRSIHALEIGFPINCILRYSY
Sbjct: 421 SSVPASLAQLVTTSNASEVASGQKIAVPATSHHFCFSIDLRSIHALEIGFPINCILRYSY 480
Query: 481 PFFGSAAPIMTNPPVEVRKNMEVFLPQSYCAFDFATMPHQLQDTFLRIPLLVELWHKDKM 540
PFFGSAAPIMTNPPVEVRKNMEVFLPQSYCAFDFATMPHQLQDTFLRIPLLVELWHKDKM
Sbjct: 481 PFFGSAAPIMTNPPVEVRKNMEVFLPQSYCAFDFATMPHQLQDTFLRIPLLVELWHKDKM 540
Query: 541 SKDLLLGIARIQLSNILSSEKTRFLGSNGEQCWRQTYSESVPVIAAQGSNNRIADLSYTV 600
SKDLLLGIARIQLSNILSSEKTRFLGSNGEQCWRQTYSESVPVIAAQGSNNRIADLSYTV
Sbjct: 541 SKDLLLGIARIQLSNILSSEKTRFLGSNGEQCWRQTYSESVPVIAAQGSNNRIADLSYTV 600
Query: 601 TLEDYGLVKMREIFISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMW 660
TLEDYGLVKMREIFISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMW
Sbjct: 601 TLEDYGLVKMREIFISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMW 660
Query: 661 KEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLE 720
KEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLE
Sbjct: 661 KEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLE 720
Query: 721 KREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDK 780
KREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDK
Sbjct: 721 KREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDK 780
Query: 781 HRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKS 840
HRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKS
Sbjct: 781 HRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKS 840
Query: 841 KLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQEL 900
KLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQEL
Sbjct: 841 KLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQEL 900
Query: 901 LDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMRTGV 960
LDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMRTGV
Sbjct: 901 LDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMRTGV 960
Query: 961 YNHEDRIISELDRQIREILAKSNASN 986
YNHEDRIISELDRQIREILAKSNASN
Sbjct: 961 YNHEDRIISELDRQIREILAKSNASN 986
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 82.0 bits (201), Expect = 2e-15
Identities = 98/432 (22%), Positives = 191/432 (44%), Gaps = 76/432 (17%)
Query: 603 EDYGLVKMREIFISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMWKE 662
E++ + +M+++F ++Q + + S E + L + E + ++
Sbjct: 150 ENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQD 209
Query: 663 MQEDIFENQ------LKQKELAHMQALAEEWK-KRDRERESL---VKKKVAEYTILEGKL 712
++ ++ + + +KEL +Q L + +R+RE E L KK ++Y E +
Sbjct: 210 LKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATI 269
Query: 713 QKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKED----------- 761
+ +L K Q++A ELQ+ K + Q+N Q L +++ + ++D
Sbjct: 270 SQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKN-QTLTENLLKKEQDYTKLEEKHNEE 328
Query: 762 ---------CIHQVELE------------------RLKIKQLEEDKHRLQQQLNDAENKY 794
+HQ +L+ +++ + E +L+++L++ E KY
Sbjct: 329 SVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKY 388
Query: 795 KILEKEFQQFKDQQNNKPE--IRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRAL 852
+ L+ EF+Q + Q+ K + ++LQSEIN L + +E ER+L A K+Q
Sbjct: 389 QHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHG---RLKEQ----- 440
Query: 853 KELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQ 912
++L+ K ++E Q+A L+ + LE+ +EK T TE Q LD + +
Sbjct: 441 RQLSSEKLMDKEQQVADLQLKLSRLEEQ------LKEKVTNSTELQHQLD----KTKQQH 490
Query: 913 QEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELD 972
QEQ+ Q ST + VL + D + I+ + L++ N IS L+
Sbjct: 491 QEQQALQQSTTAKLREAQNDLEQVLRQIGDK--DQKIQNLEALLQKSKEN-----ISLLE 543
Query: 973 RQIREILAKSNA 984
++ ++ AK A
Sbjct: 544 KEREDLYAKIQA 555
Score = 74.3 bits (181), Expect = 5e-13
Identities = 81/336 (24%), Positives = 147/336 (43%), Gaps = 60/336 (17%)
Query: 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHM-----QALAEEWKKRDRERES 696
Q E + + L+L+ E E I + KQ+E + + L++E K + E +
Sbjct: 773 QLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNN 832
Query: 697 LVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIR 756
++ V E ++ + + + +L + +L+ V L+ K E + E Q+ + D +
Sbjct: 833 RIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEK 892
Query: 757 RAKEDCIHQVELE---------RLKIKQLEEDK----------HRLQQQLNDAENKYKIL 797
KE HQ++++ LK K LE++K + +Q+QL A+N K
Sbjct: 893 TCKE-LKHQLQVQMENTLKEQKELK-KSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQN 950
Query: 798 EKEFQQFK---------DQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQW 848
EKE QQ + +Q K LQ E+ + L+K ELE KL+ QQ
Sbjct: 951 EKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQ----------QQL 1000
Query: 849 GRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEE------------KDTVKTE 896
+A +ELA K++ Q +K QE +Q++ + E ++ +
Sbjct: 1001 TQAAQELAAEKEKISVLQ-NNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLA 1059
Query: 897 RQELLDIRNELNRLRQ--QEQKQYQDSTEIASGKKD 930
+++L+ RN++ + QE K + + E S KK+
Sbjct: 1060 QEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKE 1095
Score = 61.2 bits (147), Expect = 5e-09
Identities = 69/356 (19%), Positives = 163/356 (45%), Gaps = 35/356 (9%)
Query: 649 LEYKAALELEMWKEMQEDIFENQLKQKELAHMQALA-EEWKKRDRERESLVKKKVAEYTI 707
L+++ +++E + Q+++ ++ K+KE +H L +++ + ++ +K+ E
Sbjct: 897 LKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQ 956
Query: 708 LEGKLQKTLIDLEKREQQLASVESELQ---REKKELQSERQRNLQELQDSIRRAKEDCI- 763
L+G + + E++++Q+ +++ EL+ +K EL+++ Q+ L + + KE
Sbjct: 957 LQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISV 1016
Query: 764 --HQVELERLKIKQLEEDKH-------RLQQQLNDAENKYKILEKEFQQFKDQQNNKPEI 814
+ E + KQL+ D + +Q L E K + +++ ++Q N+
Sbjct: 1017 LQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQ--- 1073
Query: 815 RLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQ 874
N L E + LE + K Q+ +AL+++ + K +E ++ K +
Sbjct: 1074 ------NKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSL-KEKELVNEKSKL 1126
Query: 875 EELEQMRLRYLAAEEKDTVKTE---RQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDG 931
E+E+++ R +EK+ K + L+ E+ L+ +Q Q E+ GK D
Sbjct: 1127 AEIEEIKCR----QEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLEL-QGKADS 1181
Query: 932 PHGSVLEEGLDDYLTR-LIEERDTLMRTGVYNHEDRIISELDRQIREILAKSNASN 986
+V +E + + + +++ + ++ E ++ SE+ +E+ K + N
Sbjct: 1182 LKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKE--KEVGMKKHEEN 1235
Score = 59.7 bits (143), Expect = 1e-08
Identities = 73/322 (22%), Positives = 142/322 (44%), Gaps = 50/322 (15%)
Query: 676 ELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQR 735
+L + A ++ ++ + ES +K+ +Y LE K ++ ++K E V++ ++
Sbjct: 689 QLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQ 748
Query: 736 EKKELQSERQRNLQ------ELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLND 789
++LQ +RQ N EL + KE V RL +++ E ++Q+L
Sbjct: 749 ALQDLQQQRQLNTDLELRATELSKQLEMEKE----IVSSTRLDLQKKSEALESIKQKLTK 804
Query: 790 AENKYKILEKEFQQFKDQ---QNNKPEIRLQ---SEINLLTLEKVELERKLESA------ 837
E + +IL+++F+ + Q+ + R+Q +E+ + +EK L +L +
Sbjct: 805 QEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSK 864
Query: 838 -------TKSKLHYKQQWGRA--------LKELARLKQ-------REQESQMARLKKQQE 875
+KS+ + Q G+A KEL Q +EQ+ L+K++E
Sbjct: 865 VSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKE 924
Query: 876 ELEQMRLRYLAAEE-----KDTVKTERQELLDIRNELNRLRQ-QEQKQYQDSTEIASGKK 929
Q++L + +E ++T+K +E ++ +N L+Q EQK+ Q K
Sbjct: 925 ASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKI 984
Query: 930 DGPHGSVLEEGLDDYLTRLIEE 951
+ LE L LT+ +E
Sbjct: 985 AVLQKTELENKLQQQLTQAAQE 1006
Score = 56.6 bits (135), Expect = 1e-07
Identities = 63/294 (21%), Positives = 134/294 (45%), Gaps = 48/294 (16%)
Query: 647 ETLEYKAALEL----EMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKV 702
ET ++ +EL E ++++E++ E + K + H++A ++ +++ E+E +
Sbjct: 357 ETSLHRIHVELSEKGEATQKLKEELSEVETKYQ---HLKAEFKQLQQQREEKEQHGLQLQ 413
Query: 703 AEYTILEGKLQKTLIDLEK------------------REQQLASVESELQREKKELQSER 744
+E L KL +T L + +EQQ+A ++ +L R +++L+ E+
Sbjct: 414 SEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLK-EK 472
Query: 745 QRNLQELQDSIRRAKEDCIHQVELER---LKIKQLEEDKHRLQQQLNDAENKYKILEKEF 801
N ELQ + + K+ Q L++ K+++ + D ++ +Q+ D + K + LE
Sbjct: 473 VTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALL 532
Query: 802 QQFKDQQNNKPEIRLQSEINLLTLEKVELERKLES--ATKSKLHYKQQWGRALKELARLK 859
Q+ K+ I+LL E+ +L K+++ + L+ Q+ L+E
Sbjct: 533 QKSKE------------NISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQL 580
Query: 860 QREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQ 913
+ ++Q K+ QE L E+K ++ + +L + +N L Q
Sbjct: 581 TEKLKNQSESHKQAQENLHDQ-----VQEQKAHLRAAQDRVLSLETSVNELNSQ 629
Score = 47.8 bits (112), Expect = 5e-05
Identities = 58/263 (22%), Positives = 114/263 (43%), Gaps = 55/263 (20%)
Query: 658 EMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLI 717
E K +Q+ E LK+KEL + ++ E ++ +E + K E + + K +
Sbjct: 1100 ERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEIT 1159
Query: 718 DLEKREQQLASVESELQREKKELQS---ERQRNLQELQDSIRRAKEDC----------IH 764
+L+ +Q L + ELQ + L++ + +RN Q L+D +++ +E+ +H
Sbjct: 1160 NLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLH 1219
Query: 765 -QVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQ---------------- 807
+++ + + +K+ EE++ +L Q+ ++KE+Q + +
Sbjct: 1220 SEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIA 1279
Query: 808 ------QNNKPEIRL--------QSEINLLTLEKVELERKLESATKSKLHYKQQWGRALK 853
QNN+ E R + EI L + +EL+RKL++ T A++
Sbjct: 1280 VLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTT-----------AAVQ 1328
Query: 854 ELARLKQREQESQMARLKKQQEE 876
EL R Q Q L ++ E
Sbjct: 1329 ELGRENQSLQIKHTQALNRKWAE 1351
Score = 37.4 bits (85), Expect = 0.070
Identities = 51/238 (21%), Positives = 101/238 (42%), Gaps = 30/238 (12%)
Query: 715 TLIDLEKREQQLASVESELQREKKELQSERQRNLQELQ----------DSIRRAKEDCIH 764
TL+ E ++ Q + E + E+ + + E+ + LQ+ + + ++ E +
Sbjct: 86 TLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLE 145
Query: 765 QVELERLKIKQL----EEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEI 820
+ + E IKQ+ E+ +L ++ D ++KY E+ ++ +Q+ + L E
Sbjct: 146 EAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYD-EERSLREAAEQKVTRLTEELNKEA 204
Query: 821 NLLTLEKVELERK--LESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQ---- 874
++ K EL ++ +E K Q + + ++RE E KK Q
Sbjct: 205 TVIQDLKTELLQRPGIEDVAVLKKELVQV-QTLMDNMTLERERESEKLKDECKKLQSQYA 263
Query: 875 -EELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQ-------KQYQDSTEI 924
E +LR A+ V QEL +++ +N L Q+ Q K+ QD T++
Sbjct: 264 SSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKL 321
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 79.0 bits (193), Expect = 2e-14
Identities = 66/294 (22%), Positives = 144/294 (48%), Gaps = 21/294 (7%)
Query: 640 EIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRE--RESL 697
E Q + L + L E +E E E + +++ L Q +W KR+ E R
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469
Query: 698 VKKKVAEYTILEGKLQKTLIDLE---------KREQQLASVESELQREKKELQSERQRNL 748
++K E + ++ + LE +REQQL + E + ++ + Q E +R
Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529
Query: 749 QEL--QDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKD 806
Q L + +RR +E+ Q+ L+R + K+LE+++ + + E + ++L++E ++ +
Sbjct: 530 QRLRSEQQLRREQEERREQL-LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQ 588
Query: 807 QQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQ 866
+ + E RL+ + +E++E E + E K + +++ + LK + ++E +
Sbjct: 589 RLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS-----EEQEERR 643
Query: 867 MARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQD 920
+L+++Q+E + RL+ EE+ + +R+ + R + L ++EQ+Q ++
Sbjct: 644 QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ--ELAEEEQEQARE 695
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/294 (26%), Positives = 153/294 (52%), Gaps = 26/294 (8%)
Query: 638 PSEIQTEPRETLEYKAALELEMW---KEMQEDIFENQLKQKELAHMQALAEEWKKRDRER 694
P E Q RE LE + E +E Q+ +F+ + ++KE + + + +++ +E
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE-EEKEWRKRETVLRKEEEKLQEE 263
Query: 695 ESLVKKKVAEYTILEGKLQKTLIDLEKRE----QQLASVESELQREKKELQSERQRNLQE 750
E ++++ E KL++ + E++E QQ E +L+R+++E + E+Q +E
Sbjct: 264 EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE 323
Query: 751 LQDSIRRAKEDCIHQV--ELERLKIKQL--EEDKHRLQQQL---NDAENKYKILEKEFQQ 803
Q+ + +E Q+ E E + +QL E+++ R +QQL + E + + L +E QQ
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE-QQ 382
Query: 804 FKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ 863
+ +Q + E +L+ E L +++ E++L + +L +QQ R +E ++ EQ
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLR--REQQLRREQQLRREQEEERHEQKHEQ 440
Query: 864 ESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQ 917
E + RLK++QEE R +L EE +TER E + +L R +++E+++
Sbjct: 441 ERREQRLKREQEE----RRDWLKREE----ETERHEQERRKQQLKRDQEEERRE 486
Score = 75.1 bits (183), Expect = 3e-13
Identities = 64/273 (23%), Positives = 135/273 (49%), Gaps = 12/273 (4%)
Query: 656 ELEMWKEMQEDIFE-NQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQK 714
E + +E+QE+ + +L+++EL + E+ ++R R + L +K+ E + + ++
Sbjct: 264 EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE 323
Query: 715 TLIDLEKREQQLASVESELQRE---KKELQSERQRNLQELQDSIRRAKEDCIHQVELERL 771
E+REQQ E +L+RE ++E Q R++ + + +RR +E+ + +L R
Sbjct: 324 ---QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
Query: 772 KIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELE 831
+ + E+ R QQ + + + + + QQ + +Q + E +L+ E E+ +
Sbjct: 381 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 832 RKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKD 891
+ E K + ++ W LK ++ EQE + +LK+ QE E+ R R+L EE++
Sbjct: 441 ERREQRLKREQEERRDW---LKREEETERHEQERRKQQLKRDQE--EERRERWLKLEEEE 495
Query: 892 TVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
+ + + +R E R+Q K+ ++ +
Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQEEEERL 528
Score = 73.9 bits (180), Expect = 7e-13
Identities = 75/268 (27%), Positives = 140/268 (52%), Gaps = 27/268 (10%)
Query: 669 ENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLAS 728
+ +L+QKE Q L EE +KR R+ +KK E L+ + ++ L E+RE++
Sbjct: 963 DKKLQQKE---EQLLGEEPEKRRRQER---EKKYREEEELQQEEEQLL--REEREKRRRQ 1014
Query: 729 VESELQREKKELQSERQRNLQE------LQDSIRRAKEDCIHQVELERLKIKQLEEDKHR 782
R+K ELQ E ++ L+E LQ+ R+ +E+ Q E E+L L E++
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL----LGEERET 1070
Query: 783 LQQQLNDAENKYKILEKEFQQFKDQ-QNNKPEIRLQSEINLLTLEKVELERKLESATKSK 841
++Q + E +Y+ E+E QQ ++Q +PE R + E E+ EL+++ E +
Sbjct: 1071 RRRQ--ELERQYR-KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEE-----Q 1122
Query: 842 LHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELL 901
L +++ R +EL R + E+E Q + +EE E+ R + L + ++ + +++E
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Query: 902 DIRNELNRLRQQEQKQYQDSTEIASGKK 929
+R E + RQ+ ++QY++ E+ K+
Sbjct: 1183 LLREEQEKRRQERERQYREEEELQRQKR 1210
Score = 73.6 bits (179), Expect = 9e-13
Identities = 61/290 (21%), Positives = 144/290 (49%), Gaps = 25/290 (8%)
Query: 649 LEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTIL 708
LE + E ++ ED E QL+++E Q L +E ++ RE E L++++
Sbjct: 1583 LEEQKVRRQEQERKFMED--EQQLRRQE--GQQQLRQERDRKFREDEQLLQER------- 1631
Query: 709 EGKLQKTLIDLEKREQQLASVESELQREKKE--LQSERQRNLQELQDSIRRAKEDCIHQV 766
++ + ++R+++ E +L+R+++E L+ +R R +E + ++ +E + +
Sbjct: 1632 ----EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ 1687
Query: 767 ELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQ-FKDQQNNKPEIRLQSEINLLTL 825
E +R K ++ E+ R +++ + + ++ +E ++ F++++ + E +
Sbjct: 1688 ERDR-KFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY 1746
Query: 826 EKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMA-----RLKKQQEELEQM 880
K+ E +L + + +Q+ R +E +L+Q +E Q+ R +++E+L Q
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE 1806
Query: 881 RL-RYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKK 929
R + L +++D +E L + + RLRQ+ +QY+ + A+ +K
Sbjct: 1807 REEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEK 1856
Score = 71.2 bits (173), Expect = 4e-12
Identities = 81/328 (24%), Positives = 149/328 (45%), Gaps = 45/328 (13%)
Query: 669 ENQLKQKELAHMQA--LAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQL 726
E QL+ +E + L EE +K R R+ ++K ++ E +LQ+ +R QQL
Sbjct: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQR-----RERAQQL 849
Query: 727 ASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQ 786
E LQ +++ +S+ QR Q+ + + ++ H + + +QL +++ LQ++
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Query: 787 LNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQ 846
+ + + + EK +Q +++Q + E Q E LL E+ + R+ K Q
Sbjct: 910 EEELQREER--EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
Query: 847 QWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAE--------------EKDT 892
Q L K+R QE + + +++EEL+Q + L E +KD
Sbjct: 968 QKEEQLLGEEPEKRRRQERE--KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
Query: 893 VKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEER 952
++ E ++LL E RL Q+ ++QY++ E+ EE L L EER
Sbjct: 1026 LQQEEEQLLREEREKRRL-QERERQYREEEELQQE----------EEQL------LGEER 1068
Query: 953 DTLMRTGV---YNHEDRIISELDRQIRE 977
+T R + Y E+ + E ++ +RE
Sbjct: 1069 ETRRRQELERQYRKEEELQQEEEQLLRE 1096
Score = 68.2 bits (165), Expect = 4e-11
Identities = 74/318 (23%), Positives = 151/318 (47%), Gaps = 37/318 (11%)
Query: 669 ENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEK---REQQ 725
E QL+++E Q ++ ++ RE E L +++ + + + +K ++ +K +EQ+
Sbjct: 1537 EQQLRRQERG--QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 726 LASVESELQREKKE----LQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEED-- 779
+E E Q ++E L+ ER R +E + ++ +E +H+ E +R K LEE+
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR---KFLEEEPQ 1651
Query: 780 ---KHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEI------------RLQSEINLLT 824
+ R QQ +D + K++ E+ Q+ ++QQ + E R + E L
Sbjct: 1652 LRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
Query: 825 ----LEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQM 880
L + ELERK + + +Q+ L+ R ++ +E Q+ +++Q+ Q
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQE---QLRRQERYRKILEEEQLRPEREEQQLRRQE 1768
Query: 881 RLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEE- 939
R R EE+ + E Q+L ++ +++ +Q ++ ++ ++DG + E+
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL 1828
Query: 940 GLDDYLTRLIEERDTLMR 957
L++ RL +ERD R
Sbjct: 1829 QLEEQEQRLRQERDRQYR 1846
Score = 67.8 bits (164), Expect = 5e-11
Identities = 68/285 (23%), Positives = 144/285 (50%), Gaps = 17/285 (5%)
Query: 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKK- 700
+ + E + + E ++ ++ +E+ E Q +++E + EE +++ RE ++
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Query: 701 ----KVAEYTILEGKLQKTLIDLEKREQQLASVESELQRE---KKELQSERQRNLQELQD 753
+ E E +L++ + E+REQQL E +L+RE ++E Q R++ L+ Q
Sbjct: 349 QQLRREQEEERREQQLRREQEE-ERREQQLRR-EQQLRREQQLRREQQLRREQQLRREQQ 406
Query: 754 SIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPE 813
R + Q+ E+ ++ EE++H +Q ++ E + + L++E ++ +D + E
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERH---EQKHEQERREQRLKREQEERRDWLKREEE 463
Query: 814 I-RLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKK 872
R + E L++ + E + E K + +++ ++ R +Q E+ Q RLK+
Sbjct: 464 TERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ--RLKR 521
Query: 873 QQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQ 917
Q+EE E+++ R + ++ + ER+E L R E RL Q+ ++Q
Sbjct: 522 QEEE-ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565
Score = 67.0 bits (162), Expect = 8e-11
Identities = 66/296 (22%), Positives = 149/296 (50%), Gaps = 18/296 (6%)
Query: 640 EIQTEPRETLEYK--AALELEMWKEMQEDIFENQLKQKELAHMQAL----AEEWKKRD-- 691
E Q+E +E LE + + E+W++ QE E + ++ E +Q+ EE+ +
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQE-WQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
Query: 692 RERESL-VKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSE---RQRN 747
R RE L +++K E + + ++ + E+ E++ E+ L++E+++LQ E RQR
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 748 LQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQ 807
LQE ++ +R+ + + + E + +Q + +L+++ + + + +E Q+ ++Q
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
Query: 808 QNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQM 867
Q + E +L+ E +++ E++ E + +L +Q+ R ++L R +Q +E Q+
Sbjct: 331 QEERREQQLRREQEERREQQLRREQE-EERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 868 AR----LKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQ 919
R ++QQ EQ R + ++ E+Q + E + + +++++ Q
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Score = 67.0 bits (162), Expect = 8e-11
Identities = 72/269 (26%), Positives = 133/269 (49%), Gaps = 26/269 (9%)
Query: 662 EMQEDIFENQLKQKELAHMQALAEEWKKRDR-ERESLVKKKVAEYTILEGKLQKTLIDLE 720
E +E E QL+++EL ++ E K++ R ER+ V ++ E E + ++T+ L
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK---EWRKRETV--LR 254
Query: 721 KREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDK 780
K E++L E + QRE +E E Q E Q+ R +E+ Q L R + + ++++
Sbjct: 255 KEEEKLQEEEPQRQRELQE--EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Query: 781 HRLQQQ---LNDAENKYKILEKEFQQFKDQQNNKPEIRLQSE------INLLTLEKVELE 831
R +QQ E + + E+ QQ + +Q + E +L+ E L E+ E
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
Query: 832 RKLESATKSKLHYKQQWGRALKELARLKQREQESQMAR---LKKQQEELEQMRLRYLAAE 888
R+ + + +L +QQ R ++L R +Q +E Q+ R L+++Q+ + +LR E
Sbjct: 373 REQQLRREQQLRREQQLRRE-QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 889 EKDTVKTERQELLDIRNELNRLRQQEQKQ 917
E+ K E++ R E R+QE+++
Sbjct: 432 ERHEQKHEQE-----RREQRLKREQEERR 455
Score = 67.0 bits (162), Expect = 8e-11
Identities = 83/353 (23%), Positives = 162/353 (45%), Gaps = 38/353 (10%)
Query: 640 EIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVK 699
E + R+ Y E E ++++++ ++ Q++L H L E ++RDRE+E
Sbjct: 1230 EKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH---LLGEQQERDREQERRRW 1286
Query: 700 KKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAK 759
++ + E +L E+ EQ+ A +E+K+L E + + Q++ R+ +
Sbjct: 1287 QQRDRHFPEEEQL-------EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339
Query: 760 EDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSE 819
E+ E E +++ E D+ +++L E K LE+E Q+ + Q+ + ++ + +
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE-QRLRRQERERKFLKEEQQ 1398
Query: 820 INLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQ---EE 876
L E E++L K ++Q + ++ K RE+E Q+ R ++++ EE
Sbjct: 1399 -----LRCQEREQQLRQDRDRKFREEEQ--QLSRQERDRKFREEEQQVRRQERERKFLEE 1451
Query: 877 LEQMRL-RYLAAEEKDTVKTERQELLDIRNELNR--------LRQQEQKQYQDSTEIASG 927
+Q+R R+ E++ + ER+E R E +R LR+QE+ + E+ S
Sbjct: 1452 EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511
Query: 928 KKDGPHGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDR---IISELDRQIRE 977
+ P LEE + L R +R L ++R + DR+ RE
Sbjct: 1512 E---PERKFLEE--EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFRE 1559
Score = 64.3 bits (155), Expect = 5e-10
Identities = 87/362 (24%), Positives = 158/362 (43%), Gaps = 56/362 (15%)
Query: 641 IQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKK 700
++ E E LE + E + +E E+ QL + E + ++ ++ +ER K
Sbjct: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSE-EQEERRQQQLRREQQERREQRLK 660
Query: 701 KVAEYTILEGKLQKTLIDLEKREQQLASVESELQREK----------------------- 737
+ E LE +L++ + E+REQ+LA E E RE+
Sbjct: 661 REEEEERLEQRLKREHEE-ERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKV 719
Query: 738 --KELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYK 795
+ + E QR QE Q+ RR +E + E ER +Q EE++ R D +++
Sbjct: 720 YSRPRKQEGQRRRQE-QEEKRRRRESELQWQEEERAHRQQQEEEQRR------DFTWQWQ 772
Query: 796 ILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKEL 855
EK ++ + + + +P +R Q E L E+ + E++ + K ++Q KEL
Sbjct: 773 AEEKS-ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKEL 831
Query: 856 ARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQ 915
L++ EQ + R ++ QEE + ++ E+++ +++ Q R++ R + +E+
Sbjct: 832 QFLEEEEQLQRRERAQQLQEEEDGLQ------EDQERRRSQEQR----RDQKWRWQLEEE 881
Query: 916 KQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQI 975
++ + T A L+E L L EE + L R E R E +RQ
Sbjct: 882 RKRRRHTLYAK--------PALQEQLRKEQQLLQEEEEELQRE---EREKRRRQEQERQY 930
Query: 976 RE 977
RE
Sbjct: 931 RE 932
Score = 62.4 bits (150), Expect = 2e-09
Identities = 70/289 (24%), Positives = 146/289 (50%), Gaps = 33/289 (11%)
Query: 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKK 701
Q E RE L L+ E K ++++ E +LK+++ L + ++R ++R +++
Sbjct: 542 QEERREQL-----LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596
Query: 702 VAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKED 761
E + ++++ L E+REQ+L E E +R ++ L+SE Q + Q +RR +++
Sbjct: 597 RLEQRLKREEVER-LEQEERREQRLKREEPEEERRQQLLKSEEQE--ERRQQQLRREQQE 653
Query: 762 CIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEIN 821
Q RLK EE++ RL+Q+L + E+ Q+ +++ + R++S I
Sbjct: 654 RREQ----RLK---REEEEERLEQRLKREHEE----ERREQELAEEEQEQARERIKSRI- 701
Query: 822 LLTLEKVELERKLESATKSKLHY--KQQWGRALKELARLKQREQESQM-----ARLKKQQ 874
+ +LE + + A +SK++ ++Q G+ ++ K+R +ES++ R +QQ
Sbjct: 702 --PKWQWQLESEAD-ARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ 758
Query: 875 EELEQMR---LRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQD 920
+E EQ R ++ A E+ + + +R + R + E++Q ++
Sbjct: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE 807
Score = 61.6 bits (148), Expect = 3e-09
Identities = 59/263 (22%), Positives = 128/263 (48%), Gaps = 26/263 (9%)
Query: 669 ENQLKQKELAHMQALAEEWKK---RDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQ 725
+ Q +++ELA + +E+ ++ RDR+R + +L + + ++RE++
Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRR-------------DEELWRQRQEWQEREER 186
Query: 726 LASVESELQ----REKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKH 781
A E +LQ E +E E Q +EL + R+ +E+ Q + ++ Q EE+K
Sbjct: 187 RAE-EEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245
Query: 782 RLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSK 841
+++ + + K+ E+E Q+ ++ Q + ++R L + E +++ + +
Sbjct: 246 WRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305
Query: 842 LHYKQQWGRALKELARLKQREQESQM-----ARLKKQQEELEQMRLRYLAAEEKDTVKTE 896
L KQ+ R ++ R +Q+E+ Q +L+++QEE + +LR EE+ +
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 897 RQELLDIRNELNRLRQQEQKQYQ 919
R++ + R + R QQ +++ Q
Sbjct: 366 REQEEERREQQLRREQQLRREQQ 388
Score = 60.8 bits (146), Expect = 6e-09
Identities = 64/297 (21%), Positives = 134/297 (45%), Gaps = 31/297 (10%)
Query: 641 IQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKK 700
+ E R + K +L + +E + FE + +Q E EE +R R++ ++
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLE--------EEPGQRRRQKRQEQER 146
Query: 701 KVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKE 760
++AE K ++ LE+R++Q E QR++ + + ER+ ++LQ E
Sbjct: 147 ELAEGEEQSEKQER----LEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETE 202
Query: 761 DCIHQVELERLKIKQLE----EDKHRLQQQLNDA----------ENKYKILEKEFQQFKD 806
+ + +L R ++ +L E+K + +++ D + +L KE ++ ++
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Query: 807 QQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQ 866
++ + + E L LE+ EL R+ + + +QQ R ++L R ++ E+ Q
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQ-----QQQRLRREQQLRRKQEEERREQ 317
Query: 867 MARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTE 923
++QQE EQ R ++ + Q+L + E R +Q ++Q ++ E
Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374
Score = 60.5 bits (145), Expect = 8e-09
Identities = 70/304 (23%), Positives = 145/304 (47%), Gaps = 29/304 (9%)
Query: 640 EIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVK 699
E +T R+ LE + E E+ +E ++ + E K++ + EE ++ +E E L++
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE-EELQQEEEQLLR 1125
Query: 700 KKVAEYTILEGKLQ-KTLIDLEKREQQLASVESELQR---------EKKELQSERQRNLQ 749
++ + E + Q + ++++ E+QL E E +R E++ELQ E ++ L+
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 750 ELQDSIRRAKE-DCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQ 808
E Q+ R+ +E + EL+R K KQ ++R + Q +D + +++ EKE +
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQ----RYRDEDQRSDLKWQWEP-EKE----NAVR 1236
Query: 809 NNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMA 868
+NK + + LE +L + L +QQ +E R +QR++
Sbjct: 1237 DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE 1296
Query: 869 RLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGK 928
+++E+ E R + EEK ++ ER+E R RQ+ +++++ ++ +
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREEREE--------KRRRQETDRKFREEEQLLQER 1348
Query: 929 KDGP 932
++ P
Sbjct: 1349 EEQP 1352
Score = 59.7 bits (143), Expect = 1e-08
Identities = 80/345 (23%), Positives = 158/345 (45%), Gaps = 40/345 (11%)
Query: 656 ELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGK---L 712
E ++ +E Q++ K +E Q L EE +++ R +E+ K + E + E + L
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQE--EKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPL 1353
Query: 713 QKTLIDLEKREQQLASVES------------ELQREKKELQSERQRNLQELQDSIRRAKE 760
++ D + RE++L E +RE+K L+ E+Q QE + +R+ ++
Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413
Query: 761 DCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNK--PEIRLQS 818
+ E ++L ++ + +QQ+ E + K LE+E QQ + +++ K E +L
Sbjct: 1414 RKFREEE-QQLSRQERDRKFREEEQQVRRQERERKFLEEE-QQLRQERHRKFREEEQLLQ 1471
Query: 819 EINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQRE---QESQMARLKKQQE 875
E L + E +RK L +QQ R ++ + +++E QE + L+++Q+
Sbjct: 1472 EREEQQLHRQERDRKF-------LEEEQQLRRQERD-RKFREQELRSQEPERKFLEEEQQ 1523
Query: 876 ELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGS 935
Q R R EE+ + ER + R + +R ++E++ Q+ E +++
Sbjct: 1524 LHRQQRQRKFLQEEQQLRRQERGQ--QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF 1581
Query: 936 VLEE---GLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIRE 977
LEE + + +E+ L R + ++ E DR+ RE
Sbjct: 1582 RLEEQKVRRQEQERKFMEDEQQLRR---QEGQQQLRQERDRKFRE 1623
Score = 58.9 bits (141), Expect = 2e-08
Identities = 90/389 (23%), Positives = 174/389 (44%), Gaps = 50/389 (12%)
Query: 625 VQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALA 684
+QQK L E + R+ E K E E+ +E ++ + E + K++ Q
Sbjct: 966 LQQKEEQL----LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR----QEWE 1017
Query: 685 EEWKKRD---RERESLVKKKVAEYTILEGKLQ-KTLIDLEKREQQLASVESELQREKK-E 739
+++K+D +E E L++++ + + E + Q + +L++ E+QL E E +R ++ E
Sbjct: 1018 RQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
Query: 740 LQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQL----------ND 789
Q ++ LQ+ ++ + R + + + E ER + EE+ + ++QL +
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE--EEELQQEEEQLLREEREKRRRQE 1135
Query: 790 AENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQ-- 847
E +Y+ E+ Q+ + +PE R + E+ E+ EL+++ E + + ++Q
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
Query: 848 --WGRALKELARLKQREQ---ESQMARLKKQQEELEQMRLR----YLAAEE-------KD 891
R +EL R K++++ E Q + LK Q E ++ +R Y E +D
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255
Query: 892 TVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYL---TRL 948
+ +RQ D+++ L QQE+ + Q+ + P LE R
Sbjct: 1256 SQLRDRQSQQDLQHLLG--EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
Query: 949 IEERDTLMRTGVYNHEDRIISELDRQIRE 977
+E L+R E R E DR+ RE
Sbjct: 1314 SQEEKQLLRE--EREEKRRRQETDRKFRE 1340
Score = 57.0 bits (136), Expect = 9e-08
Identities = 98/420 (23%), Positives = 177/420 (42%), Gaps = 108/420 (25%)
Query: 660 WKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAE----------YTILE 709
++E ++ + + ++K L Q L +E ++ RE E L++++ + + E
Sbjct: 1432 FREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEE 1491
Query: 710 GKLQKTLIDLEKREQQLASVESEL------------QREKKELQSERQ-----RNLQELQ 752
+L++ D + REQ+L S E E QR++K LQ E+Q R Q Q
Sbjct: 1492 QQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ 1551
Query: 753 DSIRRAKEDCIHQVE----------------LERLKIKQLE------EDKHRL-----QQ 785
D R+ +E+ + E LE K+++ E ED+ +L QQ
Sbjct: 1552 DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQ 1611
Query: 786 QLND------AENKYKILEKEFQQFKDQQNNK------PEIRLQSEINLL---------- 823
QL E++ + E+E QQ Q+ ++ P++R Q L
Sbjct: 1612 QLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFRE 1671
Query: 824 -----------TLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKK 872
L + E +RK + +L +++ + L+E +L+++E E + ++
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFRE-EEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
Query: 873 QQEELEQMRL----RYLAAEEKDTVKTERQELLDIRNELNR-------LRQQEQKQYQDS 921
++E EQ +L RY E++ ++ ER+E R E +R LRQ+ ++Q S
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRS 1790
Query: 922 TEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMR-----TGVYNHEDRIISELDRQIR 976
E S +K + +E + L ++RD R + E R+ E DRQ R
Sbjct: 1791 QE--SDRKFREEEQLRQEREEQQLRP--QQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR 1846
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 75.1 bits (183), Expect = 3e-13
Identities = 58/275 (21%), Positives = 139/275 (50%), Gaps = 29/275 (10%)
Query: 655 LELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQK 714
L+ EMW++ E +L+++E + + W++ +R RE EGK+++
Sbjct: 270 LQEEMWRQ------EEELREQEKKIRKQEEKMWRQEERLREQ------------EGKMRE 311
Query: 715 TLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIK 774
+ ++E++L E EL+ ++KEL+ Q+ L+E ++ ++ +E Q E R + +
Sbjct: 312 QEEKMWRQEKRLREQEKELREQEKELR--EQKELREQEEQMQEQEEKMWEQEEKMREQEE 369
Query: 775 QLEEDKHRL---QQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELE 831
++ + RL ++Q+ + E K + E+ + ++ K E + E +EK+ E
Sbjct: 370 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE 429
Query: 832 RKLESATKSKLHYKQQWGRALKELARLKQREQE--SQMARLKKQQEELEQMRLRYLAAEE 889
+K++ K +++ ++E R+++RE++ + +++Q+E++++ EE
Sbjct: 430 KKMQEQEKKTRDQEEK----MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 485
Query: 890 KDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
K+ + E + E ++++QE+K ++ +I
Sbjct: 486 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 520
Score = 68.2 bits (165), Expect = 4e-11
Identities = 60/286 (20%), Positives = 148/286 (51%), Gaps = 23/286 (8%)
Query: 656 ELEMWKEMQEDIFENQLKQKELAHMQALAEE--WKKRDRERESLVKKKVAEYTILEGKLQ 713
E +MW++ +E ++E + + +E EE W++ +R RE ++++ E + +++
Sbjct: 368 EEKMWRQ-EERLWEQEKQMREQEQKMRDQEERMWEQDERLREK--EERMREQEKMWEQVE 424
Query: 714 KTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIR------RAKEDCIHQVE 767
K + + +EQ+ + + E + +++E ER++ ++E ++++R + +E+ + + E
Sbjct: 425 KMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 768 LERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQ---NNKPEIRLQSEINLLT 824
+ + ++L E K +L +Q E + KI E+E ++ +DQ+ + ++ Q ++
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE-EKIRDQEEMWGQEKKMWRQEKMREQE 543
Query: 825 LEKVELERKLESATKSKLHYKQQWGRALKELARL------KQREQESQMARLKKQQEELE 878
+ E E K+ + +++ + +E + K RE+E R KK +EE E
Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 603
Query: 879 QMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
MR + +E++ E++E + + E ++++QE+K ++ ++
Sbjct: 604 MMREQEEKMQEQEEKMQEQEEKMWEQEE--KMQEQEEKMWEQEEKM 647
Score = 67.4 bits (163), Expect = 6e-11
Identities = 67/298 (22%), Positives = 140/298 (46%), Gaps = 36/298 (12%)
Query: 650 EYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRER-----ESLVKKKVAE 704
E K + EMW + ++ + +++++E Q +E K RD+E+ E ++KK E
Sbjct: 517 EEKIRDQEEMWGQEKKMWRQEKMREQE---DQMWEQEEKMRDQEQKMWDQEERMEKKTQE 573
Query: 705 YTILEGKLQKTLIDLEK---REQQLASVESELQREKKELQSERQRNLQELQDSIRRAKED 761
++ + + E+ RE+++ E E+ RE++E E++ +QE ++ + +E
Sbjct: 574 QEKKTWDQEEKMREEERMREREKKMRE-EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEK 632
Query: 762 CIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEIN 821
Q E + +++ E + ++ +Q E K K+ E E Q +++ +
Sbjct: 633 MQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQE--------- 683
Query: 822 LLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMR 881
EK+ + K+E T+ + K+ W + K RE+ES R KK +EE E MR
Sbjct: 684 ----EKIWEQEKMEKKTQEQ--EKKTWDQE-------KMREEESMREREKKMREEEEMMR 730
Query: 882 LRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEE 939
+ +E++ E++E ++ + ++ +QE+K ++ +K H + E+
Sbjct: 731 EQEEKMQEQEEKMQEQEE--EMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 786
Score = 66.6 bits (161), Expect = 1e-10
Identities = 71/338 (21%), Positives = 164/338 (48%), Gaps = 23/338 (6%)
Query: 647 ETLEYKAALELEMWKEMQEDIFENQLKQK--ELAHMQALAEEWKKRDRERESLVKKKVAE 704
E + + AL LE+++ I +LK+K EL LAE K + +K+K+
Sbjct: 201 ELTKERDALSLELYRNT---ITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLER 257
Query: 705 YTILEGKLQKTLIDLE--KREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDC 762
L ++Q + E ++E++L E +++++++++ + +R L+E + +R +E
Sbjct: 258 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER-LREQEGKMREQEEKM 316
Query: 763 IHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINL 822
Q + R + K+L E + L++Q E + ++ E+E + ++ ++ ++R Q E
Sbjct: 317 WRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE----KMREQEEKMW 372
Query: 823 LTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRL 882
E++ + K + K+ + Q R ++ RL RE+E +M +K E++E+MR
Sbjct: 373 RQEERLWEQEKQMREQEQKM--RDQEERMWEQDERL--REKEERMREQEKMWEQVEKMRE 428
Query: 883 RYLAAEEKDTVKTERQELLD---IRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEE 939
E++ + + +++ + IR ++R++E+ + ++ +++ +E
Sbjct: 429 EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN----MWEQE 484
Query: 940 GLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIRE 977
+ RL E+++ L ++ I E + +IR+
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 522
Score = 63.9 bits (154), Expect = 7e-10
Identities = 75/301 (24%), Positives = 137/301 (45%), Gaps = 48/301 (15%)
Query: 656 ELEMW---KEMQEDIFENQLKQKELAHMQALAEE-----------WKKRDRERESLVKKK 701
E +MW K ++E E + ++KEL + L E+ W++ ++ RE K
Sbjct: 313 EEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMW 372
Query: 702 VAEYTILEGKLQKTLIDLEKREQQLASVE-SELQREKKELQSERQRNLQEL--------- 751
E + E + Q + + R+Q+ E E REK+E E+++ +++
Sbjct: 373 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432
Query: 752 --QDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQ----LNDAENKYKILEKEFQQFK 805
Q+ R +E+ + + E R + K++ E++ +++Q EN ++ EKE+
Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW---- 488
Query: 806 DQQNNKPEIRLQSEINLLTLEKV-ELERKLESATKSKLHYKQQWGRALKELARLKQREQE 864
QQ PE Q E L EK+ E E K+ + ++ WG+ K + K REQE
Sbjct: 489 -QQQRLPE---QKE-KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 543
Query: 865 SQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELL-----DIRNELNRLRQQEQKQYQ 919
QM +Q+E++ + EE+ KT+ QE + E R+R++E+K +
Sbjct: 544 DQM---WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 920 D 920
+
Sbjct: 601 E 601
Score = 59.7 bits (143), Expect = 1e-08
Identities = 58/282 (20%), Positives = 142/282 (50%), Gaps = 13/282 (4%)
Query: 650 EYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEE--WKKRDR--ERESLVKKKVAEY 705
E K + E +E +E ++E + K +E EE W++ ++ E++ L ++K +
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 706 TILEGKLQKTLIDLEKREQQLASVESELQ-REKKELQSERQRNLQELQDSIRRAKEDCIH 764
+ + Q+ + + E++ + +E + Q +EKK E+ R + +++ ++ +E+
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREE--- 725
Query: 765 QVELERLKIKQLEEDKHRLQQQLNDA-ENKYKILEKEFQQFKDQQNNKPEIRLQSEINLL 823
E+ R + ++++E + ++Q+Q + E + K+ E+E + ++ Q+ + + +L +
Sbjct: 726 -EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 784
Query: 824 TLEKV-ELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRL 882
EK+ E E K+ + K+ +++ R +E R ++ + Q ++ Q+E++
Sbjct: 785 EQEKIWEQEEKMRDQ-EEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE 843
Query: 883 RYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
+ EEK K + QE +R + ++R QE+K + ++
Sbjct: 844 KMWGQEEKMEEKMQGQE-EKMREQEEKMRGQEEKMREQEEKM 884
Score = 58.2 bits (139), Expect = 4e-08
Identities = 53/273 (19%), Positives = 137/273 (50%), Gaps = 21/273 (7%)
Query: 656 ELEMWKEMQEDIFENQLKQKELAHMQALAEE-WKKRD-RERESLVKKKVAEYTILEGKL- 712
E E +E +E I+E + K ++ M ++ W++ RE+E + ++ + E K+
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 561
Query: 713 -QKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERL 771
Q+ ++ + +EQ+ + + E + ++E ER++ ++E ++ +R +E Q E
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE---- 617
Query: 772 KIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELE 831
K E+++ +Q+ E + K+ E+E + ++ ++ + RL + EK+
Sbjct: 618 --KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ-----KEKLWEH 670
Query: 832 RKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKD 891
K++ K + ++ W + +++ + Q +++ + K ++EE MR R E++
Sbjct: 671 EKMQEQEKMQEQEEKIWEQ--EKMEKKTQEQEKKTWDQEKMREEE--SMREREKKMREEE 726
Query: 892 TVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
+ E++E + + E ++++QE++ ++ ++
Sbjct: 727 EMMREQEEKMQEQEE--KMQEQEEEMWEQEEKM 757
Score = 53.9 bits (128), Expect = 7e-07
Identities = 62/283 (21%), Positives = 136/283 (48%), Gaps = 45/283 (15%)
Query: 656 ELEMWKE---MQEDIFENQLK---QKELAHMQALAEEWKKRDRERESLVKKKVAEYTILE 709
E +MW + M++ E + K Q+E + E +K+ RE E +++++ E
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ-------E 609
Query: 710 GKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELE 769
K+Q+ ++++E+++ E ++Q E++ + E ++ + +E Q L
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQ--------EQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 770 RLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNK---PEIRLQSEINLLTLE 826
K K E +K + Q+++ + E KI E+E + K Q+ K + +++ E ++ E
Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEE--KIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719
Query: 827 KV---------ELERKL-ESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEE 876
K E E K+ E K + ++ W +E +Q E+ + RL +Q+E+
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWE---QEEKMWEQEEKMWEQQRLPEQKEK 776
Query: 877 L---EQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQK 916
L E+M+ + E+++ ++ + +++ R + ++R QE+K
Sbjct: 777 LWEHEKMQEQEKIWEQEEKMRDQEEKM---RGQEEKMRGQEEK 816
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 74.7 bits (182), Expect = 4e-13
Identities = 79/318 (24%), Positives = 148/318 (46%), Gaps = 52/318 (16%)
Query: 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKK---------RDR 692
Q E + LE + LE + +E +++I + ++EL + L EW++ R++
Sbjct: 406 QLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQL--EWERNRRQELLNQRNK 463
Query: 693 ERESLV----KKKVAEYTI---------LEGKLQKTLIDLEKREQQLASVE--------- 730
E+E +V KKK E+ + LEGKLQ L + Q++ S
Sbjct: 464 EQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAE 523
Query: 731 -SELQREKKELQSERQRNLQE---LQDSIRRAKEDCIHQVELERLK--IKQLEEDKHRLQ 784
+ LQ++ +E Q R + E L D +++ +++ +H+ L LK ++ E + L+
Sbjct: 524 ITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLR 583
Query: 785 QQLNDAENKYKILEKEFQQFKDQQ------NNKPEIRLQSEINLLTLEKVELERKLESAT 838
QL++ E + + +E F +Q +NK +++ Q + L++ E ERK+
Sbjct: 584 DQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELE 643
Query: 839 KSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQ 898
K K +++ K+ Q+E E Q R ++E+L+ R + ++KD + +Q
Sbjct: 644 KQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLK----REESVKKKDGEEKGKQ 699
Query: 899 ELLDIRNELNRLRQQEQK 916
E D +L RL Q Q+
Sbjct: 700 EAQD---KLGRLFHQHQE 714
Score = 69.3 bits (168), Expect = 2e-11
Identities = 93/369 (25%), Positives = 164/369 (44%), Gaps = 93/369 (25%)
Query: 638 PSEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKE-LAHMQALAEEWKKRDRERES 696
P + + RE E + LELE + ++ + E Q K++E LA ++ +E K+R+R+ +
Sbjct: 347 PVTFEDKKRENFE-RGNLELE---KRRQALLEQQRKEQERLAQLERAEQERKERERQEQE 402
Query: 697 LVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNL-------Q 749
+K+ E LE +L+K +LE++ ++ E E +RE + + ERQR L Q
Sbjct: 403 --RKRQLE---LEKQLEKQR-ELERQREEERRKEIE-RREAAKRELERQRQLEWERNRRQ 455
Query: 750 ELQDSIRRAKEDCI--------------------HQVE-----------LERLKIKQLEE 778
EL + + +ED + HQ+E +R +I+ +
Sbjct: 456 ELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNK 515
Query: 779 DKH-------RLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKV--- 828
+ LQQQL +++ L E Q DQ + L + +L+TL++
Sbjct: 516 SRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRD-SLVTLKRALEA 574
Query: 829 -ELER--------KLESATKSKLHYKQQWGRALKEL-----------------ARLKQRE 862
EL R ++E T+SKL + LKEL RLKQ+E
Sbjct: 575 KELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKE 634
Query: 863 QESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDST 922
QE ++ L+KQ+EE ++ A+E+D E + D +L ++E+ + ++S
Sbjct: 635 QERKIIELEKQKEEAQR------RAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESV 688
Query: 923 EIASGKKDG 931
+ G++ G
Sbjct: 689 KKKDGEEKG 697
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/201 (25%), Positives = 96/201 (47%), Gaps = 17/201 (8%)
Query: 728 SVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQL 787
SV+ L E+ L+ E+Q+ ++L + K + + LE LE+ + L +Q
Sbjct: 324 SVDQRLP-EEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLE------LEKRRQALLEQQ 376
Query: 788 NDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQ 847
+ + LE+ Q+ K+++ + E + Q E+ ++ ELER+ E + ++ ++
Sbjct: 377 RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERRE- 435
Query: 848 WGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNEL 907
A +EL R +Q E E + Q EQ + L A++K T++ E + L D +++L
Sbjct: 436 --AAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKK-TLEFELEALNDKKHQL 492
Query: 908 N------RLRQQEQKQYQDST 922
R R Q+Q +ST
Sbjct: 493 EGKLQDIRCRLTTQRQEIEST 513
Score = 35.4 bits (80), Expect = 0.27
Identities = 28/106 (26%), Positives = 54/106 (50%), Gaps = 12/106 (11%)
Query: 826 EKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYL 885
E+ +LE+KL + K ++ + R EL + +Q E Q +K+QE L Q+
Sbjct: 338 EQQQLEKKLPVTFEDKK--RENFERGNLELEKRRQALLEQQ----RKEQERLAQLERAEQ 391
Query: 886 AAEEKDTVKTERQELLDI------RNELNRLRQQEQKQYQDSTEIA 925
+E++ + ER+ L++ + EL R R++E+++ + E A
Sbjct: 392 ERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAA 437
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 74.7 bits (182), Expect = 4e-13
Identities = 79/318 (24%), Positives = 148/318 (46%), Gaps = 52/318 (16%)
Query: 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKK---------RDR 692
Q E + LE + LE + +E +++I + ++EL + L EW++ R++
Sbjct: 406 QLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQL--EWERNRRQELLNQRNK 463
Query: 693 ERESLV----KKKVAEYTI---------LEGKLQKTLIDLEKREQQLASVE--------- 730
E+E +V KKK E+ + LEGKLQ L + Q++ S
Sbjct: 464 EQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAE 523
Query: 731 -SELQREKKELQSERQRNLQE---LQDSIRRAKEDCIHQVELERLK--IKQLEEDKHRLQ 784
+ LQ++ +E Q R + E L D +++ +++ +H+ L LK ++ E + L+
Sbjct: 524 ITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLR 583
Query: 785 QQLNDAENKYKILEKEFQQFKDQQ------NNKPEIRLQSEINLLTLEKVELERKLESAT 838
QL++ E + + +E F +Q +NK +++ Q + L++ E ERK+
Sbjct: 584 DQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELE 643
Query: 839 KSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQ 898
K K +++ K+ Q+E E Q R ++E+L+ R + ++KD + +Q
Sbjct: 644 KQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLK----REESVKKKDGEEKGKQ 699
Query: 899 ELLDIRNELNRLRQQEQK 916
E D +L RL Q Q+
Sbjct: 700 EAQD---KLGRLFHQHQE 714
Score = 69.3 bits (168), Expect = 2e-11
Identities = 93/369 (25%), Positives = 164/369 (44%), Gaps = 93/369 (25%)
Query: 638 PSEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKE-LAHMQALAEEWKKRDRERES 696
P + + RE E + LELE + ++ + E Q K++E LA ++ +E K+R+R+ +
Sbjct: 347 PVTFEDKKRENFE-RGNLELE---KRRQALLEQQRKEQERLAQLERAEQERKERERQEQE 402
Query: 697 LVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNL-------Q 749
+K+ E LE +L+K +LE++ ++ E E +RE + + ERQR L Q
Sbjct: 403 --RKRQLE---LEKQLEKQR-ELERQREEERRKEIE-RREAAKRELERQRQLEWERNRRQ 455
Query: 750 ELQDSIRRAKEDCI--------------------HQVE-----------LERLKIKQLEE 778
EL + + +ED + HQ+E +R +I+ +
Sbjct: 456 ELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNK 515
Query: 779 DKH-------RLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKV--- 828
+ LQQQL +++ L E Q DQ + L + +L+TL++
Sbjct: 516 SRELRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRD-SLVTLKRALEA 574
Query: 829 -ELER--------KLESATKSKLHYKQQWGRALKEL-----------------ARLKQRE 862
EL R ++E T+SKL + LKEL RLKQ+E
Sbjct: 575 KELARQHLRDQLDEVEKETRSKLQEIDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKE 634
Query: 863 QESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDST 922
QE ++ L+KQ+EE ++ A+E+D E + D +L ++E+ + ++S
Sbjct: 635 QERKIIELEKQKEEAQR------RAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESV 688
Query: 923 EIASGKKDG 931
+ G++ G
Sbjct: 689 KKKDGEEKG 697
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/201 (25%), Positives = 96/201 (47%), Gaps = 17/201 (8%)
Query: 728 SVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQL 787
SV+ L E+ L+ E+Q+ ++L + K + + LE LE+ + L +Q
Sbjct: 324 SVDQRLP-EEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLE------LEKRRQALLEQQ 376
Query: 788 NDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQ 847
+ + LE+ Q+ K+++ + E + Q E+ ++ ELER+ E + ++ ++
Sbjct: 377 RKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERRE- 435
Query: 848 WGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNEL 907
A +EL R +Q E E + Q EQ + L A++K T++ E + L D +++L
Sbjct: 436 --AAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKK-TLEFELEALNDKKHQL 492
Query: 908 N------RLRQQEQKQYQDST 922
R R Q+Q +ST
Sbjct: 493 EGKLQDIRCRLTTQRQEIEST 513
Score = 35.4 bits (80), Expect = 0.27
Identities = 28/106 (26%), Positives = 54/106 (50%), Gaps = 12/106 (11%)
Query: 826 EKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYL 885
E+ +LE+KL + K ++ + R EL + +Q E Q +K+QE L Q+
Sbjct: 338 EQQQLEKKLPVTFEDKK--RENFERGNLELEKRRQALLEQQ----RKEQERLAQLERAEQ 391
Query: 886 AAEEKDTVKTERQELLDI------RNELNRLRQQEQKQYQDSTEIA 925
+E++ + ER+ L++ + EL R R++E+++ + E A
Sbjct: 392 ERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAA 437
>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
Length = 1044
Score = 73.6 bits (179), Expect = 9e-13
Identities = 98/340 (28%), Positives = 160/340 (47%), Gaps = 44/340 (12%)
Query: 669 ENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTI--LEGKLQKTLIDLEKREQQL 726
+++L+ K+L + + E K R + S KK+ E T+ LE ++QK + ++ ++L
Sbjct: 669 QHELEIKKLKELMSATE--KARREKWISEKTKKIKEVTVRGLEPEIQKLIARHKQEVRRL 726
Query: 727 ASV-ESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQ 785
S+ E+EL + + R +EL++ + R KE + Q E ER + +Q E L+Q
Sbjct: 727 KSLHEAELLQSDERASQRCLRQAEELREQLEREKE-ALGQQERERARQRQRAE-LEELRQ 784
Query: 786 QLNDAENKY-KILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHY 844
QL ++ + + L EF++ +++Q E R Q E+N L +++ELER+ A
Sbjct: 785 QLEESSSALTRALRAEFEKGREEQ----ERRHQMELNTLK-QQLELERQAWEA------- 832
Query: 845 KQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRY-----LAAEEKDTVKTERQE 899
GR KE A L REQE + K + +E+E + R LA EE + R +
Sbjct: 833 ----GRTRKEEAWLLNREQELREEIRKGRDKEIELVIHRLEADMALAKEESEKAAESRIK 888
Query: 900 LL--DIRNELNRLRQQEQKQYQDSTEI------ASGKKDGPHGSV--LEEGLDDYLT--- 946
L EL+ L Q E+K + +E+ A G+ G V E L+D
Sbjct: 889 RLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGLVRQKERALEDAQAVNE 948
Query: 947 RLIEERDTLMRTGVYNHEDRIIS--ELDRQIREILAKSNA 984
+L ER L + EDR+ + E RQ + LA A
Sbjct: 949 QLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQA 988
Score = 52.0 bits (123), Expect = 3e-06
Identities = 74/281 (26%), Positives = 128/281 (45%), Gaps = 30/281 (10%)
Query: 657 LEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYT-ILEGKLQKT 715
LE+ E+ + +L+ +E L + + R+ L ++V E L +LQ+
Sbjct: 560 LELGSEVSTSVMRLKLEVEEKKQAMLLLQRALAQQRD---LTARRVKETEKALSRQLQRQ 616
Query: 716 LIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQ 775
E Q+ + +L +KK L + + + EL+ +R E L+IK+
Sbjct: 617 REHYEATIQRHLAFIDQLIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQAQHELEIKK 676
Query: 776 LEE-----DKHRLQQQLNDAENKYKI-----LEKEFQQFKDQQNNKPEI-RLQS--EINL 822
L+E +K R ++ +++ K K LE E Q K +K E+ RL+S E L
Sbjct: 677 LKELMSATEKARREKWISEKTKKIKEVTVRGLEPEIQ--KLIARHKQEVRRLKSLHEAEL 734
Query: 823 LTLEKVELERKLESATKSKLHY---KQQWGRALKELARLKQREQESQMARLKKQQEELEQ 879
L ++ +R L A + + K+ G+ +E AR +QR +++ L++Q EE
Sbjct: 735 LQSDERASQRCLRQAEELREQLEREKEALGQQERERARQRQR---AELEELRQQLEESSS 791
Query: 880 MRLRYLAAE-EKDTVKTERQELLDIRNELNRLRQQEQKQYQ 919
R L AE EK + ER+ + ELN L+QQ + + Q
Sbjct: 792 ALTRALRAEFEKGREEQERRHQM----ELNTLKQQLELERQ 828
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 71.2 bits (173), Expect = 4e-12
Identities = 78/326 (23%), Positives = 154/326 (47%), Gaps = 51/326 (15%)
Query: 635 APCPSEIQTEPRETLEYK-AALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRE 693
AP +Q+ P E + + A+ + K ++ + L++KE H A+ K +E
Sbjct: 505 APIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKE 564
Query: 694 RESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQD 753
+ ++ ++ +E+R+++L S+ +QREK+EL+ +R+ LQ+
Sbjct: 565 HQRILARRQT---------------IEERKERLESLN--IQREKEELE-QREAELQK--- 603
Query: 754 SIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFK-----DQQ 808
+R+A+E+ + Q ER K + L+E + ++ + + + K E + FK D +
Sbjct: 604 -VRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLE 662
Query: 809 NNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQ--REQESQ 866
P+ + ++ L EK EL+ +L++ K K+ Y ++ + L+E+ +K EQ +
Sbjct: 663 ELDPDFIMAKQVEQLEKEKKELQERLKNQEK-KIDYFER-AKRLEEIPLIKSAYEEQRIK 720
Query: 867 MARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIAS 926
L +QQEE E T++ ER++ L+ +N ++R+ + ++
Sbjct: 721 DMDLWEQQEE-----------ERITTMQLEREKALEHKNRMSRMLEDR--------DLFV 761
Query: 927 GKKDGPHGSVLEEGLDDYLTRLIEER 952
+ SV EE L + RL EER
Sbjct: 762 MRLKAARQSVYEEKLKQFEERLAEER 787
Score = 65.5 bits (158), Expect = 2e-10
Identities = 82/303 (27%), Positives = 137/303 (45%), Gaps = 50/303 (16%)
Query: 641 IQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRD-RERESLVK 699
IQ E +E LE + A EL+ ++ +E+ + K++E + E+ KK+ RER +K
Sbjct: 587 IQRE-KEELEQREA-ELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIK 644
Query: 700 KKVAEYTILEGKLQKTLIDLEKREQQ-----LASVESELQREKKELQSERQRNLQELQDS 754
K T L K K ID+E E+ +A +L++EKKELQ ER +N ++ D
Sbjct: 645 K-----TELGAKAFKD-IDIEDLEELDPDFIMAKQVEQLEKEKKELQ-ERLKNQEKKIDY 697
Query: 755 IRRAKE-------------------DCIHQVELERLKIKQLE-----EDKHRLQQQLNDA 790
RAK D Q E ER+ QLE E K+R+ + L D
Sbjct: 698 FERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDR 757
Query: 791 E--------NKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEK-VELERKLESATKSK 841
+ + + E++ +QF+++ + RL+ E+ + R+ E + +
Sbjct: 758 DLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRR 817
Query: 842 LHYKQQWGRALKELARLKQREQESQ--MARLKKQQEELEQMRLRYLAAEEKDTVKTERQE 899
+ R +E A +RE+E + R+KK +E + R R L EE++ + E +
Sbjct: 818 AEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERR 877
Query: 900 LLD 902
L D
Sbjct: 878 LGD 880
Score = 39.3 bits (90), Expect = 0.018
Identities = 35/168 (20%), Positives = 84/168 (50%), Gaps = 13/168 (7%)
Query: 661 KEMQEDIFENQLKQKE--LAHMQALAEEWKKRDRERESLV---------KKKVAEYTILE 709
K ++ ++E +LKQ E LA + E +KR R+ E + +++ AE +L+
Sbjct: 765 KAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLK 824
Query: 710 GKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELE 769
+ ++ + KRE++L + +++ ++ + +RQR L+ + RR +E + L
Sbjct: 825 EREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLS 884
Query: 770 RLKIKQLEEDKHRLQQQLNDAENKYK--ILEKEFQQFKDQQNNKPEIR 815
R + + D ++ +A+++++ EKE+++ + + ++ R
Sbjct: 885 RKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRR 932
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 70.9 bits (172), Expect = 6e-12
Identities = 84/420 (20%), Positives = 185/420 (44%), Gaps = 48/420 (11%)
Query: 552 QLSNILSSEKTRFLGSNGEQCWRQTYSESVPVIAAQGSNNRIADLSYTVTLEDYGLVKMR 611
Q + +L+ ++ L S +Q + + N I ++ +V++ D G +
Sbjct: 629 QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWEL 688
Query: 612 EIFISDSS--QGVSAVQQKPSSLPPAPCPSEIQ----TEPRETLEYKAALELEMWKEMQE 665
+ S + +G S + P P ++Q + + + + E+ +E +E
Sbjct: 689 QPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEE 748
Query: 666 DIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQ 725
+ +L++++ ++ EE +KR RE E L ++K E + + Q+ + ++ E++
Sbjct: 749 RKRQEELRRQQEEILRRQQEEERKR-REEEELARRKQEE-ALRRQREQEIALRRQREEEE 806
Query: 726 LASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQ 785
E L+R ++ + E +R QE + +R+ +E+ E ++LEE++ R+++
Sbjct: 807 RQQQEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 864
Query: 786 Q---LNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKL 842
+ L E + K E E Q+ K+ + + Q E L +++ +++ + + KL
Sbjct: 865 EAARLRHEEEERKRKELEVQRQKELMRQRQQ---QQE----ALRRLQQQQQQQQLAQMKL 917
Query: 843 HYKQQWGR-------------ALKELARLK----------QREQESQMARLKKQQEELEQ 879
WG+ +L E+ +L+ QR Q+ ++ + +QQ++ +Q
Sbjct: 918 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQ 977
Query: 880 MRLRYLAAEEKDTVKTERQELLDIRNELNR---LRQQEQKQYQDSTEIASGKKDGPHGSV 936
+L K + T + LL+I+ E R +QQ+Q+Q+Q + H S+
Sbjct: 978 QKLSGWGNVSKPSGTT--KSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1035
Score = 63.2 bits (152), Expect = 1e-09
Identities = 58/277 (20%), Positives = 127/277 (45%), Gaps = 22/277 (7%)
Query: 706 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQ 765
T G + L LEK + + + E +R + E++++R+ ++ Q+ +RR +E+ + +
Sbjct: 710 TTTPGPALEQLQQLEKAK----AAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRR 765
Query: 766 VELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTL 825
+ E K ++ EE R Q++ + + +I + ++ +++Q + +R E
Sbjct: 766 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---- 821
Query: 826 EKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ---ESQMARLKKQQEELEQMRL 882
+ E RK E + + +W R +E R + + E + ARL+ ++EE ++ L
Sbjct: 822 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 881
Query: 883 RYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLD 942
+K+ ++ +Q+ + L RL+QQ+Q+Q ++ S G +
Sbjct: 882 E--VQRQKELMRQRQQQ----QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQ 935
Query: 943 DYLT-----RLIEERDTLMRTGVYNHEDRIISELDRQ 974
L+ +L EER+ +R + ++ L +Q
Sbjct: 936 ATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ 972
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 70.9 bits (172), Expect = 6e-12
Identities = 84/420 (20%), Positives = 185/420 (44%), Gaps = 48/420 (11%)
Query: 552 QLSNILSSEKTRFLGSNGEQCWRQTYSESVPVIAAQGSNNRIADLSYTVTLEDYGLVKMR 611
Q + +L+ ++ L S +Q + + N I ++ +V++ D G +
Sbjct: 656 QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWEL 715
Query: 612 EIFISDSS--QGVSAVQQKPSSLPPAPCPSEIQ----TEPRETLEYKAALELEMWKEMQE 665
+ S + +G S + P P ++Q + + + + E+ +E +E
Sbjct: 716 QPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEE 775
Query: 666 DIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQ 725
+ +L++++ ++ EE +KR RE E L ++K E + + Q+ + ++ E++
Sbjct: 776 RKRQEELRRQQEEILRRQQEEERKR-REEEELARRKQEE-ALRRQREQEIALRRQREEEE 833
Query: 726 LASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQ 785
E L+R ++ + E +R QE + +R+ +E+ E ++LEE++ R+++
Sbjct: 834 RQQQEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 891
Query: 786 Q---LNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKL 842
+ L E + K E E Q+ K+ + + Q E L +++ +++ + + KL
Sbjct: 892 EAARLRHEEEERKRKELEVQRQKELMRQRQQ---QQE----ALRRLQQQQQQQQLAQMKL 944
Query: 843 HYKQQWGR-------------ALKELARLK----------QREQESQMARLKKQQEELEQ 879
WG+ +L E+ +L+ QR Q+ ++ + +QQ++ +Q
Sbjct: 945 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQ 1004
Query: 880 MRLRYLAAEEKDTVKTERQELLDIRNELNR---LRQQEQKQYQDSTEIASGKKDGPHGSV 936
+L K + T + LL+I+ E R +QQ+Q+Q+Q + H S+
Sbjct: 1005 QKLSGWGNVSKPSGTT--KSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1062
Score = 63.2 bits (152), Expect = 1e-09
Identities = 58/277 (20%), Positives = 127/277 (45%), Gaps = 22/277 (7%)
Query: 706 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQ 765
T G + L LEK + + + E +R + E++++R+ ++ Q+ +RR +E+ + +
Sbjct: 737 TTTPGPALEQLQQLEKAK----AAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRR 792
Query: 766 VELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTL 825
+ E K ++ EE R Q++ + + +I + ++ +++Q + +R E
Sbjct: 793 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---- 848
Query: 826 EKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ---ESQMARLKKQQEELEQMRL 882
+ E RK E + + +W R +E R + + E + ARL+ ++EE ++ L
Sbjct: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 908
Query: 883 RYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLD 942
+K+ ++ +Q+ + L RL+QQ+Q+Q ++ S G +
Sbjct: 909 E--VQRQKELMRQRQQQ----QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQ 962
Query: 943 DYLT-----RLIEERDTLMRTGVYNHEDRIISELDRQ 974
L+ +L EER+ +R + ++ L +Q
Sbjct: 963 ATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ 999
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 70.9 bits (172), Expect = 6e-12
Identities = 84/420 (20%), Positives = 185/420 (44%), Gaps = 48/420 (11%)
Query: 552 QLSNILSSEKTRFLGSNGEQCWRQTYSESVPVIAAQGSNNRIADLSYTVTLEDYGLVKMR 611
Q + +L+ ++ L S +Q + + N I ++ +V++ D G +
Sbjct: 635 QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWEL 694
Query: 612 EIFISDSS--QGVSAVQQKPSSLPPAPCPSEIQ----TEPRETLEYKAALELEMWKEMQE 665
+ S + +G S + P P ++Q + + + + E+ +E +E
Sbjct: 695 QPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEE 754
Query: 666 DIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQ 725
+ +L++++ ++ EE +KR RE E L ++K E + + Q+ + ++ E++
Sbjct: 755 RKRQEELRRQQEEILRRQQEEERKR-REEEELARRKQEE-ALRRQREQEIALRRQREEEE 812
Query: 726 LASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQ 785
E L+R ++ + E +R QE + +R+ +E+ E ++LEE++ R+++
Sbjct: 813 RQQQEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 870
Query: 786 Q---LNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKL 842
+ L E + K E E Q+ K+ + + Q E L +++ +++ + + KL
Sbjct: 871 EAARLRHEEEERKRKELEVQRQKELMRQRQQ---QQE----ALRRLQQQQQQQQLAQMKL 923
Query: 843 HYKQQWGR-------------ALKELARLK----------QREQESQMARLKKQQEELEQ 879
WG+ +L E+ +L+ QR Q+ ++ + +QQ++ +Q
Sbjct: 924 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQ 983
Query: 880 MRLRYLAAEEKDTVKTERQELLDIRNELNR---LRQQEQKQYQDSTEIASGKKDGPHGSV 936
+L K + T + LL+I+ E R +QQ+Q+Q+Q + H S+
Sbjct: 984 QKLSGWGNVSKPSGTT--KSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041
Score = 63.2 bits (152), Expect = 1e-09
Identities = 58/277 (20%), Positives = 127/277 (45%), Gaps = 22/277 (7%)
Query: 706 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQ 765
T G + L LEK + + + E +R + E++++R+ ++ Q+ +RR +E+ + +
Sbjct: 716 TTTPGPALEQLQQLEKAK----AAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRR 771
Query: 766 VELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTL 825
+ E K ++ EE R Q++ + + +I + ++ +++Q + +R E
Sbjct: 772 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---- 827
Query: 826 EKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ---ESQMARLKKQQEELEQMRL 882
+ E RK E + + +W R +E R + + E + ARL+ ++EE ++ L
Sbjct: 828 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
Query: 883 RYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLD 942
+K+ ++ +Q+ + L RL+QQ+Q+Q ++ S G +
Sbjct: 888 E--VQRQKELMRQRQQQ----QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQ 941
Query: 943 DYLT-----RLIEERDTLMRTGVYNHEDRIISELDRQ 974
L+ +L EER+ +R + ++ L +Q
Sbjct: 942 ATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ 978
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 70.9 bits (172), Expect = 6e-12
Identities = 84/420 (20%), Positives = 185/420 (44%), Gaps = 48/420 (11%)
Query: 552 QLSNILSSEKTRFLGSNGEQCWRQTYSESVPVIAAQGSNNRIADLSYTVTLEDYGLVKMR 611
Q + +L+ ++ L S +Q + + N I ++ +V++ D G +
Sbjct: 635 QYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWEL 694
Query: 612 EIFISDSS--QGVSAVQQKPSSLPPAPCPSEIQ----TEPRETLEYKAALELEMWKEMQE 665
+ S + +G S + P P ++Q + + + + E+ +E +E
Sbjct: 695 QPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEE 754
Query: 666 DIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQ 725
+ +L++++ ++ EE +KR RE E L ++K E + + Q+ + ++ E++
Sbjct: 755 RKRQEELRRQQEEILRRQQEEERKR-REEEELARRKQEE-ALRRQREQEIALRRQREEEE 812
Query: 726 LASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQ 785
E L+R ++ + E +R QE + +R+ +E+ E ++LEE++ R+++
Sbjct: 813 RQQQEEALRRLEERRREEEERRKQE--ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 870
Query: 786 Q---LNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKL 842
+ L E + K E E Q+ K+ + + Q E L +++ +++ + + KL
Sbjct: 871 EAARLRHEEEERKRKELEVQRQKELMRQRQQ---QQE----ALRRLQQQQQQQQLAQMKL 923
Query: 843 HYKQQWGR-------------ALKELARLK----------QREQESQMARLKKQQEELEQ 879
WG+ +L E+ +L+ QR Q+ ++ + +QQ++ +Q
Sbjct: 924 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQ 983
Query: 880 MRLRYLAAEEKDTVKTERQELLDIRNELNR---LRQQEQKQYQDSTEIASGKKDGPHGSV 936
+L K + T + LL+I+ E R +QQ+Q+Q+Q + H S+
Sbjct: 984 QKLSGWGNVSKPSGTT--KSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSI 1041
Score = 63.2 bits (152), Expect = 1e-09
Identities = 58/277 (20%), Positives = 127/277 (45%), Gaps = 22/277 (7%)
Query: 706 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQ 765
T G + L LEK + + + E +R + E++++R+ ++ Q+ +RR +E+ + +
Sbjct: 716 TTTPGPALEQLQQLEKAK----AAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRR 771
Query: 766 VELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTL 825
+ E K ++ EE R Q++ + + +I + ++ +++Q + +R E
Sbjct: 772 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---- 827
Query: 826 EKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ---ESQMARLKKQQEELEQMRL 882
+ E RK E + + +W R +E R + + E + ARL+ ++EE ++ L
Sbjct: 828 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
Query: 883 RYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLD 942
+K+ ++ +Q+ + L RL+QQ+Q+Q ++ S G +
Sbjct: 888 E--VQRQKELMRQRQQQ----QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQ 941
Query: 943 DYLT-----RLIEERDTLMRTGVYNHEDRIISELDRQ 974
L+ +L EER+ +R + ++ L +Q
Sbjct: 942 ATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ 978
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 70.9 bits (172), Expect = 6e-12
Identities = 67/291 (23%), Positives = 139/291 (47%), Gaps = 16/291 (5%)
Query: 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEE---------WKKRD- 691
Q E + E K + E +E +E I E + K + M EE W+K +
Sbjct: 366 QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 425
Query: 692 -RERESLVKKKVAEYTILEGKL--QKTLIDLEKREQQLASVESELQREKKELQSERQRN- 747
R +E ++ +K + LE K+ Q+ + + E++ Q+ + + +R+++E + RQ
Sbjct: 426 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 485
Query: 748 LQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQ 807
++E ++ IR +E Q E + K EE+K + Q+++ E K + E+ ++Q +
Sbjct: 486 IREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI 545
Query: 808 QNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQM 867
+ +IR Q E EK+ + + + K+ +++ R +E R ++ + Q
Sbjct: 546 HEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE 605
Query: 868 ARLKKQQEELEQMRLRYLAAEEKDTVKTE--RQELLDIRNELNRLRQQEQK 916
++Q+E++ + + EEK + E R++ IR + ++R+QE+K
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEK 656
Score = 68.9 bits (167), Expect = 2e-11
Identities = 62/340 (18%), Positives = 155/340 (45%), Gaps = 53/340 (15%)
Query: 656 ELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKT 715
E E+W + NQ +++++ + +EW+++ +E+E ++++ + E K+++
Sbjct: 348 ENELWNRL------NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 401
Query: 716 LIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQ 775
+ ++E+++ E E+ EK+E ++ + E ++ IR +E Q ++ + K+
Sbjct: 402 EEMMWEKEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 460
Query: 776 LEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLE 835
EE+K R Q++ + E K E++ ++ +++ + E + E + EK+ E K +
Sbjct: 461 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQ 520
Query: 836 SAT------------------KSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEEL 877
K K+H +++ R +E ++ + Q ++++Q+E++
Sbjct: 521 EQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKV 580
Query: 878 EQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVL 937
+ + EEK IR + ++R+QE+ + ++
Sbjct: 581 WRQEEKIREQEEK------------IREQEEKIREQEEMTQEQEEKMGE----------Q 618
Query: 938 EEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIRE 977
EE + + ++ E+ + + R ++ I E +++IRE
Sbjct: 619 EEKMCEQEEKMQEQEEKMRR------QEEKIREQEKKIRE 652
Score = 67.8 bits (164), Expect = 5e-11
Identities = 63/279 (22%), Positives = 142/279 (50%), Gaps = 24/279 (8%)
Query: 656 ELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKT 715
ELE QE I E + K++E + E +KR +E+E+ + ++ + E K+++
Sbjct: 442 ELEEKMHEQEKIREQEEKRQE----EEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQ 496
Query: 716 LIDLEKREQQLASVESELQREKKELQSERQRNLQEL--QDSIRRAKEDCIHQVELERLKI 773
+ ++E+++ E + EK++ Q E R +++ Q+ I R KE Q E KI
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEE----KI 552
Query: 774 KQLEEDKHRLQQQLNDAENKYKILEKEF----QQFKDQQNN----KPEIRLQSEINLLTL 825
++ EE R +++++D E K + E++ ++ ++Q+ + +IR Q E+
Sbjct: 553 RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQE 612
Query: 826 EKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYL 885
EK+ + + + K+ +++ R +E R ++++ Q ++++Q+E +++ +
Sbjct: 613 EKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 672
Query: 886 AAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
EEK E++E + + E ++R+QE+K ++ +
Sbjct: 673 EQEEK---MCEQEEKMQEQEE--KMRRQEEKMWEQEVRL 706
Score = 63.9 bits (154), Expect = 7e-10
Identities = 64/286 (22%), Positives = 141/286 (49%), Gaps = 31/286 (10%)
Query: 668 FENQLKQKELAHMQALAEEWKKRDRERESLVKKKVA------EYTILEGKLQKTLIDLEK 721
F +L+Q + A+A + KK DR E L K++ A TI + +L++ L++
Sbjct: 234 FAGELEQA----LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE 289
Query: 722 REQQLASVESELQREKKELQSERQR-----NLQELQ----------DSIRRAKEDCIHQV 766
+ Q + S +SE+Q KEL+ + +R Q+LQ S+ + + +
Sbjct: 290 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN 349
Query: 767 ELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQ-QNNKPEIRLQSEINLLTL 825
EL +Q EE R ++++ + E K + E++ ++ +++ + + ++R Q E+
Sbjct: 350 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 409
Query: 826 EKVELERKL--ESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLR 883
EK+ + ++ E K + + W + +++ L+++ E + R +++++ E+ ++R
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKIRELEEKMHEQEKIR-EQEEKRQEEEKIR 467
Query: 884 YLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKK 929
++ K RQE IR + ++R+QE+K ++ +I +K
Sbjct: 468 EQEKRQEQEAKMWRQE-EKIREQEEKIREQEEKMWRQEEKIHEQEK 512
Score = 48.1 bits (113), Expect = 4e-05
Identities = 41/197 (20%), Positives = 99/197 (50%), Gaps = 11/197 (5%)
Query: 650 EYKAALELEMWKEMQEDIFENQLK----QKELAHMQALAEEWKKRDRERESLVKKKVAEY 705
E K + E+W++ +E I E + K ++++ + + +++ RE+E V ++ +
Sbjct: 529 EEKIREQEEIWRQ-KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI 587
Query: 706 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQ 765
E K+++ + ++E+ + + E E++E E++ +QE ++ +RR +E Q
Sbjct: 588 REQEEKIREQEEKIREQEE-MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ 646
Query: 766 ---VELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINL 822
+ + KI++ EE ++++ + E K E++ Q+ +++ + E + E+ L
Sbjct: 647 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 706
Query: 823 LTLEK--VELERKLESA 837
E+ E + LE+A
Sbjct: 707 RQQEEKMQEHQEHLEAA 723
Score = 32.7 bits (73), Expect = 1.7
Identities = 20/119 (16%), Positives = 63/119 (52%), Gaps = 1/119 (0%)
Query: 640 EIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVK 699
E+ E E + + E ++MQE + + +++++ + E +++ RE+E +++
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665
Query: 700 KKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRA 758
++ + E K+ + ++++E+++ E ++ ++ L+ + ++ +QE Q+ + A
Sbjct: 666 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK-MQEHQEHLEAA 723
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 70.5 bits (171), Expect = 7e-12
Identities = 72/307 (23%), Positives = 149/307 (48%), Gaps = 34/307 (11%)
Query: 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEE---------WKKRDR 692
Q E + E K + E +E +E I E + K + M EE W+K ++
Sbjct: 305 QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 364
Query: 693 ER--ESLVKKKVAEYTILEGKL--QKTLIDLEKREQQLASVESELQREKKELQSERQRN- 747
R E ++ +K + LE K+ Q+ + + E++ Q+ + + +R+++E + RQ
Sbjct: 365 MRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 424
Query: 748 LQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQ 807
++E ++ IR ++ Q E + K EE+K + Q+++ E K + E+ ++Q K++
Sbjct: 425 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ-KEK 483
Query: 808 QNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQ------- 860
+ + +IR Q E EK+ + + + K+ +++ R +E R ++
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
Query: 861 ---REQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQ 917
+EQE +M +++ +E E+MR + EEK + E+ IR + ++R+QE+K
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQ----EEKIREQEEK-----IREQKEKIREQEEKI 594
Query: 918 YQDSTEI 924
++ +I
Sbjct: 595 WEQEEKI 601
Score = 62.4 bits (150), Expect = 2e-09
Identities = 61/288 (21%), Positives = 140/288 (48%), Gaps = 25/288 (8%)
Query: 650 EYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILE 709
E + E E ++ +E I E + +Q++ A M W++ ++ RE ++K+ E
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKM------WRQEEKIREQ--EEKIREQEKKM 439
Query: 710 GKLQKTLIDLEK-REQQLASVESELQREKKELQSE----RQRNLQELQDSIRRAKEDCIH 764
+ ++ + + EK RE++ + E+ R++++++ + RQ+ Q+ IR+ +E
Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWR 499
Query: 765 QVEL---ERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEIN 821
Q E + KI++ EE R ++++ + E K + E++ ++ ++ + E + E
Sbjct: 500 QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 559
Query: 822 LLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMR 881
+ EK+ + + + K+ +++ R +E ++ + Q +++Q+E++ +
Sbjct: 560 MQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE 619
Query: 882 LRYLAAEEK---DTVKTERQELLDIRNELNRLRQQEQK-----QYQDS 921
+ EEK K RQE E+ RLRQQE+K ++ ++
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKMWEQEV-RLRQQEEKMQEHQEHLEA 666
Score = 61.6 bits (148), Expect = 3e-09
Identities = 79/355 (22%), Positives = 169/355 (47%), Gaps = 41/355 (11%)
Query: 647 ETLEYKAALELEMWKEMQEDIFENQLKQK--ELAHMQALAEEWKKRDRERESLVKKKVAE 704
E + + AL LE+++ I + +LK+K +L L E K + +K+K+
Sbjct: 197 ELTKERDALSLELYRNT---ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
Query: 705 YTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIH 764
+L + Q+ + + ++L SV ++LQ + +E +E L + Q+ +E+ I
Sbjct: 254 AKLLLPQ-QQLQAEADHLGKELQSVSAKLQAQVEE--NELWNRLNQQQEEKMWRQEEKIQ 310
Query: 765 QVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLT 824
+ E KI++ EE ++++ + E K + E+ + +++ + E+ + E +
Sbjct: 311 EWE---EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 367
Query: 825 LEKV---------ELERKLESATK-SKLHYKQQWGRALKELARLKQREQESQMAR----L 870
LE++ ELE K+ K + K+Q ++E + K++EQE++M R +
Sbjct: 368 LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE--QEKRQEQEAKMWRQEEKI 425
Query: 871 KKQQEELEQMRLRYLAAEEK----DTVKTE--RQELLDIRNELNRLRQQEQ--KQYQDST 922
++Q+E++ + + EEK + ++ E RQE ++ + ++R+QE+ +Q +
Sbjct: 426 REQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMH 485
Query: 923 EIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIRE 977
E +K EE + D ++ E+ + + R ++ I E + +IRE
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR------QEEKIREQEEKIRE 534
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 70.5 bits (171), Expect = 7e-12
Identities = 75/318 (23%), Positives = 158/318 (49%), Gaps = 19/318 (5%)
Query: 621 GVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHM 680
G + +Q + S+ P P+E++ + + +A K QED E + K+ E
Sbjct: 516 GSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSAS-----KASQEDANEIKSKRDEEERE 570
Query: 681 QALAEEWKKRDRERESLVKKKVAEYTILEGKLQK-TLIDLEKRE-----QQLASVESELQ 734
+ E+ ++R+RERE +++ + + E + ++ + D EK + ++ A + +L+
Sbjct: 571 RERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLK 630
Query: 735 REKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKY 794
E K+ Q E Q+ ++ L D R A ++ +V+L + K+ + + L+Q+L D E+K
Sbjct: 631 IELKKAQ-ESQKEMKLLLDMYRSAPKEQRDKVQLMAAE-KKSKAELEDLRQRLKDLEDKE 688
Query: 795 KILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKE 854
K KE ++ D+ + ++ +I L +K+ + ++ E A S++ Q ++E
Sbjct: 689 K---KENKKMADEDALRKIRAVEEQIEYLQ-KKLAMAKQEEEALLSEMDVTGQAFEDMQE 744
Query: 855 L-ARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQEL-LDIRNELNRLRQ 912
RL Q+ +E A K E ++ ++ L EEK+ + + L + +L +R+
Sbjct: 745 QNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRK 804
Query: 913 QEQKQYQDSTEIASGKKD 930
E+K++ + I +G+K+
Sbjct: 805 LEEKEHLLQSNIGTGEKE 822
Score = 39.7 bits (91), Expect = 0.014
Identities = 55/277 (19%), Positives = 115/277 (41%), Gaps = 28/277 (10%)
Query: 669 ENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLAS 728
+N + ++ + + + + R +E L+++K + KLQ + E R L S
Sbjct: 210 DNLIVEEAVQELNSFLAQENMRLQELTDLLQEKHRTMSQEFSKLQSKVETAESRVSVLES 269
Query: 729 VESELQREKKELQSERQRNLQELQDSIRRAKE---------DCIHQVELERLKIKQLEED 779
+ +LQ + +++ QR + L + + R ++ + + ++ EE
Sbjct: 270 MIDDLQWDIDKIRKREQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTI-TINARKFEEM 328
Query: 780 KHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATK 839
L++ A+N+ LEK Q F+ E+ Q+E KVEL +E K
Sbjct: 329 NAELEENKELAQNRLCELEKLRQDFE-------EVTTQNE-----KLKVELRSAVEQVVK 376
Query: 840 SKLHYK---QQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTE 896
Y+ Q+ E +LK E++ L Q ++ + +E K
Sbjct: 377 ETPEYRCMQSQFSVLYNESLQLKAHLDEAR--TLLHGTRGTHQHQVELIERDEVSLHKKL 434
Query: 897 RQELLDIRNELNRLRQQ-EQKQYQDSTEIASGKKDGP 932
R E++ + + L ++R++ E + + +A+ ++ GP
Sbjct: 435 RTEVIQLEDTLAQVRKEYEMLRIEFEQTLAANEQAGP 471
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 70.5 bits (171), Expect = 7e-12
Identities = 92/380 (24%), Positives = 170/380 (44%), Gaps = 43/380 (11%)
Query: 643 TEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKV 702
TE + L+ + E+E +E E E LK KE+ QA EE ++ E+ + K
Sbjct: 628 TEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEII-FQAHIEEMNEKTLEK---LDVKQ 683
Query: 703 AEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQS---ERQRNLQELQDSIRRAK 759
E L +L + L K E++L+ ++ + + K+EL++ E++ + Q+ DSI +
Sbjct: 684 TELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEH 743
Query: 760 EDCIHQVE------LERLKIKQLEEDKHRLQQQ--LNDAENKYKILEKEFQQ-------F 804
E I + E + +L++ E DKH + Q + + E K E E QQ F
Sbjct: 744 EVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVF 803
Query: 805 KDQQNNKPEIRLQSEINLLTLEK--VELERKLESATKSKLHYKQQWGRALKELARLKQRE 862
+ Q+ E E L L++ ++LE + TK + Q EL K +
Sbjct: 804 QSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV 863
Query: 863 QESQMARLKKQQEELEQ----MRLRYLAAEEKDTVKTE--RQELLDIRNELNRLRQQEQK 916
Q+ M +L+KQ E+EQ + Y + E + E +Q L++ N + ++R+ ++K
Sbjct: 864 QD-LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKK 922
Query: 917 QYQDSTEIASGKKDGPHGSVLEEGLD----------DYLTRLIEERDTLMRTGVYNHEDR 966
+ + T+ S K+D H +L E + + + + +E ++ + + E +
Sbjct: 923 EIEILTQKLSAKEDSIH--ILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAK 980
Query: 967 IISELDRQIREILAKSNASN 986
+ EL+ E+ K N
Sbjct: 981 LKKELENTALELSQKEKQFN 1000
Score = 63.2 bits (152), Expect = 1e-09
Identities = 76/364 (20%), Positives = 157/364 (43%), Gaps = 48/364 (13%)
Query: 649 LEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTIL 708
LE K M +++ + E + QKE + Q A E + + + + + + T++
Sbjct: 1299 LEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLM 1358
Query: 709 EGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVEL 768
+ +L++ +++ +QL + +LQ SE++ + L+ K + + QV+
Sbjct: 1359 KEELKEKKVEISSLSKQLTDLNVQLQNSIS--LSEKEAAISSLRKQYDEEKCELLDQVQD 1416
Query: 769 ERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQ-QFKDQQNNKPEIRLQSEI------- 820
K+ L ++K +Q++D NK+ +K+ Q +F QN E+++Q E+
Sbjct: 1417 LSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYE 1476
Query: 821 --NLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELE 878
+ L K EL+++ + K + + K+ + L + E +SQ AR+ + ++ +
Sbjct: 1477 KDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNL-ETELKSQTARIMELEDHIT 1535
Query: 879 QMRLRYLAAEE--------KDTVKTERQELLDIRNEL-----NRLRQQEQK-------QY 918
Q + + E KD E + L EL NR+++ E+K Y
Sbjct: 1536 QKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVY 1595
Query: 919 QDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIREI 978
E+ + KK+ H ++ + ++ L L EDR+ SE ++ E+
Sbjct: 1596 SMKAELETKKKELEHVNLSVKSKEEELKAL---------------EDRLESESAAKLAEL 1640
Query: 979 LAKS 982
K+
Sbjct: 1641 KRKA 1644
Score = 63.2 bits (152), Expect = 1e-09
Identities = 73/294 (24%), Positives = 130/294 (44%), Gaps = 50/294 (17%)
Query: 646 RETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEY 705
++T+E ++ E+ Q+DI +L QK L H Q L EE R +E E +
Sbjct: 1536 QKTIEIESLNEVLKNYNQQKDIEHKELVQK-LQHFQELGEEKDNRVKEAEEKI------- 1587
Query: 706 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQ------SERQRNLQELQDSIRRAK 759
TL E Q+ S+++EL+ +KKEL+ ++ L+ L+D R
Sbjct: 1588 --------LTL------ENQVYSMKAELETKKKELEHVNLSVKSKEEELKALED--RLES 1631
Query: 760 EDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSE 819
E EL+R +++ K +L Q+ + E +YK K + + N K + R + E
Sbjct: 1632 ESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYK---KGTESHLSELNTKLQER-ERE 1687
Query: 820 INLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQ 879
+++ LE KL+S S+ A A +Q E +SQ K +E++
Sbjct: 1688 VHI-------LEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISV 1740
Query: 880 MR---------LRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
++ L+ + E+++TV + + + L +L E KQ++D + I
Sbjct: 1741 LQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMI 1794
Score = 61.6 bits (148), Expect = 3e-09
Identities = 62/293 (21%), Positives = 148/293 (50%), Gaps = 30/293 (10%)
Query: 657 LEMWKEMQEDIFENQLKQKELA-HMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKT 715
LE+ +++ + EN+ + K+LA H++A E K ++E +V+K E L K Q+
Sbjct: 570 LELESSLEKSLQENKNQSKDLAVHLEA---EKNKHNKEITVMVEKHKTELESL--KHQQD 624
Query: 716 LIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQ 775
+ EK + ++E+++ +++ + E++ L++ ++ I +A + +++ LE+L +KQ
Sbjct: 625 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKD-KEIIFQAHIEEMNEKTLEKLDVKQ 683
Query: 776 LEED------------KHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLL 823
E + +H+L+++L+ +++ +++E + D+Q N + ++ S ++
Sbjct: 684 TELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDS---II 740
Query: 824 TLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLR 883
+V ++R E A K +++ + + + + Q E+ A +K+ + EL+Q +
Sbjct: 741 KEHEVSIQR-TEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAK 799
Query: 884 ------YLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKD 930
Y +A + T K ++L ++ +L L + + E+ + KKD
Sbjct: 800 LDVFQSYQSATHEQT-KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKD 851
Score = 58.9 bits (141), Expect = 2e-08
Identities = 69/345 (20%), Positives = 155/345 (44%), Gaps = 45/345 (13%)
Query: 664 QEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILE-----GKLQKTLID 718
+E + + ++KE + ++ ++ R + +E L+K + AE E G LQ+ L +
Sbjct: 1748 KEKLLQRVGQEKE----ETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEE 1803
Query: 719 LEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKED----------------- 761
K+ + + E + K +Q+++ NL+ + D +++ ++
Sbjct: 1804 KNKKYSLIVAQHVEKEGGKNNIQAKQ--NLENVFDDVQKTLQEKELTCQILEQKIKELDS 1861
Query: 762 -CIHQVELERLKIKQLEEDKHRLQ--QQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQS 818
+ Q E+ R+++++L +LQ QQ++ ++LE+ ++ +P++
Sbjct: 1862 CLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKL---- 1917
Query: 819 EINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELE 878
++ + + +LE KL A + K ++ R K+L R+ ++E + ++ LKK E +
Sbjct: 1918 -LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDL-RMLRKEHQQELEILKK---EYD 1972
Query: 879 QMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLE 938
Q R + E++D L + E N Q++++ + + + K +LE
Sbjct: 1973 QEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLE 2032
Query: 939 ---EGLDDYLTRLIEERDTLMRTGVYNHE--DRIISELDRQIREI 978
E + L ++ E+ D L RT E D E+ ++R++
Sbjct: 2033 SHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDL 2077
Score = 58.5 bits (140), Expect = 3e-08
Identities = 75/352 (21%), Positives = 167/352 (47%), Gaps = 41/352 (11%)
Query: 652 KAALELEMWKEMQEDIFEN-QLKQKELAHMQALAEEWKKRDRERES-LVKKKVAEYTILE 709
+A+ +L++++ Q E + +++LA +Q K D E E L+ K+VAE +E
Sbjct: 795 QASAKLDVFQSYQSATHEQTKAYEEQLAQLQQ-----KLLDLETERILLTKQVAE---VE 846
Query: 710 GKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQ----ELQDSIRRAKEDCIHQ 765
+ + +L+ + Q+ + +L+++ E++ + + Q +L+D + ++
Sbjct: 847 AQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQIL 906
Query: 766 VELERLKIKQLEEDKHRLQ---QQLNDAENKYKILEKEFQ-QFKDQQNNKPEIRLQSEIN 821
VE E + ++ E K ++ Q+L+ E+ IL +E++ +FK+Q+ +++ +++
Sbjct: 907 VEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEM 966
Query: 822 LLTLEK------VELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQE 875
TL+K +L+++LE+ ++Q+ + E+A+ ++RL+ Q+
Sbjct: 967 QETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK 1026
Query: 876 ELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQ---QEQKQYQDSTEIASGKKDGP 932
E + E D + ++L EL + + QE++Q E+A K+
Sbjct: 1027 EQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQ-----EVAELKQKIL 1081
Query: 933 HGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIREILAKSNA 984
+E ++ +T L EE GV +D ++EL Q+++ A N+
Sbjct: 1082 LFGCEKEEMNKEITWLKEE-------GV--KQDTTLNELQEQLKQKSAHVNS 1124
Score = 58.2 bits (139), Expect = 4e-08
Identities = 85/410 (20%), Positives = 172/410 (41%), Gaps = 56/410 (13%)
Query: 589 SNNRIADLSYTVTLEDYGLVKMREIF---ISDSSQGVSAVQQKPSSLPP----APCPSEI 641
S RIA+L + ++ ++E F + + Q +S +Q + S L P ++
Sbjct: 185 SLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDV 244
Query: 642 QTEPRETLEYKAAL--ELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVK 699
+P LE +A + + E + E + E+ K L +Q +R + +E+L+K
Sbjct: 245 -LKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQ-------QRVKRQENLLK 296
Query: 700 KKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAK 759
+ + TI K Q TL+ EK Q E ER + L++++D K
Sbjct: 297 R--CKETIQSHKEQCTLLTSEKEALQ-------------EQLDERLQELEKIKDLHMAEK 341
Query: 760 EDCIHQVELERLKIKQLEED--------KHRLQQQLNDAENKYKILEKEFQQFKDQQNNK 811
I Q+ + I+QLE+D K ++ + L E + L +Q Q
Sbjct: 342 TKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEEL 401
Query: 812 PEIRLQSEINLLTLEKVELERKLESATK---SKLHYKQQWGRALKELARLKQREQESQMA 868
E + +SE ELE+ L +A K ++ K + +K + + + E+ S
Sbjct: 402 REQKEKSERAAFE----ELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQ 457
Query: 869 RLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGK 928
L + ++E+ + + + K +EL EL + Q ++++Q+ ++A K
Sbjct: 458 ELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEK 517
Query: 929 KDGPHGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIREI 978
+ + +E E++++L + + I++E + ++R++
Sbjct: 518 SQSEYLKISQEK---------EQQESLALEELELQKKAILTESENKLRDL 558
Score = 57.0 bits (136), Expect = 9e-08
Identities = 87/414 (21%), Positives = 173/414 (41%), Gaps = 61/414 (14%)
Query: 515 ATMPHQLQDTFLRIPLLVELWHKDKMSKDLLLGIARIQLSNILSSEKTRFLGSNGEQCWR 574
A + +L++T L EL K+K +L +A+ + I S +R + EQ
Sbjct: 979 AKLKKELENTAL------ELSQKEKQFNAKMLEMAQANSAGI-SDAVSRLETNQKEQI-- 1029
Query: 575 QTYSESVPVIAAQGSNNRIADLSYTVTLEDYGLVKMREIFISDSSQGVSAVQQKPSSLPP 634
ES+ + + N+ I+ + + L ++ EI + + Q V+ ++QK +
Sbjct: 1030 ----ESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQK---ILL 1082
Query: 635 APCPSEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRER 694
C E + L+ + + E+QE QLKQK AH+ +LA++ K
Sbjct: 1083 FGCEKEEMNKEITWLKEEGVKQDTTLNELQE-----QLKQKS-AHVNSLAQDETK----- 1131
Query: 695 ESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDS 754
L+ L+K +DL K ++ ++ +L E K L E +R + EL
Sbjct: 1132 -------------LKAHLEKLEVDLNKSLKENTFLQEQLV-ELKMLAEEDKRKVSELTSK 1177
Query: 755 IRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEI 814
++ E+ + L+ + + L D ++K L +E D K E
Sbjct: 1178 LKTTDEE-----------FQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEA 1226
Query: 815 RLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQ 874
L+++ N E + + +A S++ + Q +KE +K A+L++
Sbjct: 1227 LLEAKTN----ELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLT 1282
Query: 875 EELEQMRLRYLAA-----EEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTE 923
EE + + + A E+++ +K+ + ++ + E L+++ Q Q ++E
Sbjct: 1283 EEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASE 1336
Score = 55.5 bits (132), Expect = 2e-07
Identities = 61/276 (22%), Positives = 119/276 (43%), Gaps = 43/276 (15%)
Query: 652 KAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRE-RESLVKKKVAEYTILEG 710
K + E ++M E + ++K++E+A +++ ++ + E RE K + A + LE
Sbjct: 362 KGMVIAETKRQMHETL---EMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEK 418
Query: 711 KLQKTLIDLEKR-------EQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCI 763
L E R ++Q+ ++E + E+ LQ E R QE+ D ++++ E+ I
Sbjct: 419 ALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQI 478
Query: 764 HQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLL 823
+L++L K+L + L ++L E ++F++Q
Sbjct: 479 --AKLQKLHEKELARKEQELTKKLQTRE----------REFQEQM--------------- 511
Query: 824 TLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLR 883
KV LE+ K +QQ AL+EL K+ +L+ Q+E E R R
Sbjct: 512 ---KVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTR 568
Query: 884 YLAAEE--KDTVKTERQELLDIRNELNRLRQQEQKQ 917
L E + +++ + + D+ L + + K+
Sbjct: 569 ILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKE 604
Score = 54.7 bits (130), Expect = 4e-07
Identities = 72/288 (25%), Positives = 137/288 (47%), Gaps = 51/288 (17%)
Query: 661 KEMQEDIFENQLK--------QKEL--AHMQALAEEWKKRDRERESLVKKKVAEYTILEG 710
KE+ I E ++K QKE+ M+ L +++K ++ + K E +LE
Sbjct: 1845 KELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTE--LLEE 1902
Query: 711 KLQ----------KTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKE 760
+ K L ++E + L + +REK++L E R LQ +R ++
Sbjct: 1903 NTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVR----LQKDLRMLRK 1958
Query: 761 DCIHQVELERLKIKQLEEDKHRLQQQLNDAENKY----KILEKEFQQFKDQQNNKPEIRL 816
+ HQ ELE LK + +E + +++Q+ D E K+ K L +EF Q+ + E+ +
Sbjct: 1959 E--HQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTI 2016
Query: 817 QSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEE 876
+ IN ++VE E LES ++++ + LK++A E++ + R K+ EE
Sbjct: 2017 KETIN--KAQEVEAE-LLES-------HQEETNQLLKKIA-----EKDDDLKRTAKRYEE 2061
Query: 877 LEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
+ R + A+ +D ++T+ +EL + + + +QE+ D+ I
Sbjct: 2062 ILDAREEEMTAKVRD-LQTQLEEL---QKKYQQKLEQEENPGNDNVTI 2105
Score = 46.2 bits (108), Expect = 2e-04
Identities = 74/363 (20%), Positives = 161/363 (44%), Gaps = 44/363 (12%)
Query: 657 LEMWKEMQEDIFENQLKQKELAHMQA--LAEEWKKRDRERESLVKKKVAEYTILEGKLQK 714
+ + E E F+NQ K+ E +A + E KK+ ++E+ +KK++ E T LE ++
Sbjct: 938 IHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKEL-ENTALELSQKE 996
Query: 715 TLID---LEKREQQLASVESELQR----EKKELQSERQRNLQELQDSI----RRAKEDCI 763
+ LE + A + + R +K++++S + + +EL D I ++ +
Sbjct: 997 KQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1056
Query: 764 HQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKD----QQNNKPEIRLQ-- 817
E+ +++++ E++ L+Q++ + + + KE K+ Q E++ Q
Sbjct: 1057 ELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLK 1116
Query: 818 ---SEINLLTLEKVELERKLE------SATKSKLHYKQQWGRALKELARLKQREQESQMA 868
+ +N L ++ +L+ LE + + + + Q+ LK LA +R+ +
Sbjct: 1117 QKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTS 1176
Query: 869 RLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQ---DSTEIA 925
+LK EE + ++ ++ EK E + L E +L ++ Q TE
Sbjct: 1177 KLKTTDEEFQSLK----SSHEKSNKSLEDKSL-----EFKKLSEELAIQLDICCKKTEAL 1227
Query: 926 SGKKDGPHGSVLEEGLDDYLTRL--IEERDTLMRTGVYNHEDRIISELDRQIREILAKSN 983
K ++ + L+R+ + R T ++ + + +SEL+ Q+R++ + N
Sbjct: 1228 LEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLI-KTCTVSELEAQLRQLTEEQN 1286
Query: 984 ASN 986
N
Sbjct: 1287 TLN 1289
Score = 43.5 bits (101), Expect = 0.001
Identities = 65/333 (19%), Positives = 139/333 (41%), Gaps = 63/333 (18%)
Query: 711 KLQKTLIDLEKREQQLASVESELQREKKELQ--------------SERQRNLQELQDSIR 756
+++++L + +L + LQREKK+LQ +E + LQ Q + +
Sbjct: 145 RMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKK 204
Query: 757 RAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKI------LEKEFQQFKDQQN- 809
+E+ +E + I L+ L+Q+L + + LE + + F ++N
Sbjct: 205 HLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENP 264
Query: 810 ---NKPEI--------------RLQSEINLLTLEKVELERKLESA---TKSKLHYKQQWG 849
+P + R++ + NLL K ++ E T K ++Q
Sbjct: 265 ESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLD 324
Query: 850 RALKELARLKQREQE------SQMARLKKQQEELEQMRLRYLAAEEK---DTVKTERQEL 900
L+EL ++K +Q+ K E+LEQ + +A ++ +T++ + +E+
Sbjct: 325 ERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEI 384
Query: 901 LDIRNELNRLRQQ-----EQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTL 955
+R+ + ++ Q EQK+ + +K EE + E+ T+
Sbjct: 385 AQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTI 444
Query: 956 MRTGVYNHEDRI-----ISELDRQIREILAKSN 983
+T + E+RI +S + +++ +++ KS+
Sbjct: 445 EKT---SEEERISLQQELSRVKQEVVDVMKKSS 474
Score = 38.9 bits (89), Expect = 0.024
Identities = 77/345 (22%), Positives = 140/345 (40%), Gaps = 54/345 (15%)
Query: 659 MWKEMQEDIFENQLK-QKELAHMQALAEE-WKKRDRERESLVKKKVAEYTILE--GKLQK 714
M+K++++ I E Q + Q+ LA QA + R R R S +++ E T G Q
Sbjct: 1 MFKKLKQKISEEQQQLQQALAPAQASSNSSTPTRMRSRTSSFTEQLDEGTPNRESGDTQS 60
Query: 715 TLIDLEKREQQLASV------ESELQREKKE--LQSERQRNLQELQDSIRRAKEDCIHQV 766
L+ R + S+ ES + KE +++ + +L L A D +
Sbjct: 61 FAQKLQLRVPSVESLFRSPIKESLFRSSSKESLVRTSSRESLNRLDLDSSTASFDPPSDM 120
Query: 767 ELER---------LKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQ 817
+ E L +QL + R+++ L+ KY L +Q + ++ I Q
Sbjct: 121 DSEAEDLVGNSDSLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQ 180
Query: 818 SEINLLTLEKVELERKLESATKSKLHYKQQWGRALKE-----------LARLKQREQESQ 866
S+ L EL +L+ ++K H ++++ +L+E ++ LKQR +
Sbjct: 181 SQDKSLR-RIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGP 239
Query: 867 M-ARLKKQQEELEQMRLRYLAAEEKD--------------TVKTERQELLDIRNELNRLR 911
M + K +LE + E + T++T +Q + N L R +
Sbjct: 240 MNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCK 299
Query: 912 QQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLM 956
+ Q + T + S K+ L+E LD+ L L + +D M
Sbjct: 300 ETIQSHKEQCTLLTSEKE------ALQEQLDERLQELEKIKDLHM 338
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 70.1 bits (170), Expect = 1e-11
Identities = 67/298 (22%), Positives = 145/298 (48%), Gaps = 21/298 (7%)
Query: 639 SEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEE--WKKRD--RER 694
+E+ + E K + E +E +E I E + K +E EE W+K + R +
Sbjct: 276 NELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 335
Query: 695 ESLVKKKVAEYTILEGKL--QKTLIDLEKREQQLASVESELQREKKELQSERQRN-LQEL 751
E ++ +K + LE K+ Q+ + + E++ Q+ + + +R+++E + RQ ++E
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 395
Query: 752 QDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEF-QQFKDQQNN 810
++ IR +E Q E K+ + EE ++++ + E K + E++ +Q K +
Sbjct: 396 EEKIREQEEMMQEQEE----KMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ 451
Query: 811 KPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARL 870
+ +IR Q E+ EK+ + ++K+ +++ R +E R ++++ Q ++
Sbjct: 452 EEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI 511
Query: 871 KKQQEELEQMRLRYLAAEEKDTVKTE---------RQELLDIRNELNRLRQQEQKQYQ 919
++Q+E +++ + EEK + E R++ +R + RLRQQE+K +
Sbjct: 512 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 66.2 bits (160), Expect = 1e-10
Identities = 67/288 (23%), Positives = 139/288 (48%), Gaps = 13/288 (4%)
Query: 639 SEIQTEPRET---LEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEE---WKKRDR 692
SEIQ +E LE L + + + D +L Q A +QA EE W + ++
Sbjct: 226 SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL-QSVSAKLQAQVEENELWNRLNQ 284
Query: 693 ERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQ 752
++E + ++ + E K+Q+ + ++E+++ E E+ EK+E ++ + E +
Sbjct: 285 QQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQE-EMMWEKEEKMRRQEEMMWEKE 343
Query: 753 DSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKP 812
+ IR +E Q ++ + K+ EE+K R Q++ + E K E++ ++ +++ +
Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403
Query: 813 EIRLQSEINLLTLEKVELERKLE-SATKSKLHYKQQWGRALKELARLKQ---REQESQMA 868
E+ + E + E+ E++ E + K+ +++ R ++ R ++ REQE M
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 463
Query: 869 RLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQK 916
+++ E E A ++ K RQE IR + ++R+QE+K
Sbjct: 464 EQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE-EKIREQEKKIREQEEK 510
Score = 66.2 bits (160), Expect = 1e-10
Identities = 55/273 (20%), Positives = 141/273 (51%), Gaps = 19/273 (6%)
Query: 656 ELEMWKEMQEDIFENQLKQKE-LAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQK 714
E E+W + + E +Q+E + + +E +++ RE+E ++++ E K+++
Sbjct: 275 ENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRR 334
Query: 715 TLIDLEKREQQLASVESEL-QREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKI 773
+ ++E+++ +E ++ ++EK Q E+++ +++++ +R +++ ++ + KI
Sbjct: 335 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA--KMWRQEEKI 392
Query: 774 KQLEEDKHRLQQQLNDAENKY-KILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELER 832
++ EE ++ + + E K + EK ++Q ++ Q + ++R Q E K+ +
Sbjct: 393 REQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEE-------KIREQE 445
Query: 833 KLESATKSKLHYKQQWGRALKELARLKQREQESQMARLK-KQQEELEQMRLRYLAAEEKD 891
K + K+ +++ + +E K EQE +M + K QE+ E+MR + E++
Sbjct: 446 KKIREQEEKIREQEEMMQEQEE----KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501
Query: 892 TVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
E++E IR + +++QE+K ++ ++
Sbjct: 502 KKIREQEE--KIREQEEMMQEQEEKMWEQEEKM 532
Score = 59.7 bits (143), Expect = 1e-08
Identities = 85/380 (22%), Positives = 163/380 (42%), Gaps = 50/380 (13%)
Query: 614 FISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLE---YKAALELEMWKEMQEDIFEN 670
F + Q +SAV + A E T+ R+ L Y+ + E KE + E
Sbjct: 161 FAGELEQALSAVATQKKK---ADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK 217
Query: 671 -QLKQKELAHMQALAEEWKKRDRERESLVKKKVA---------EYTILEGKLQKTLIDLE 720
QL + E + +Q +E K++ + L+ ++ E + KLQ + + E
Sbjct: 218 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 277
Query: 721 KREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDK 780
+ E ++ R+++++Q ER+ +QE ++ IR +E Q E+ + + EE
Sbjct: 278 LWNRLNQQQEEKMWRQEEKIQ-EREEKIQEQEEKIREQEEKMRRQEEM----MWEKEEKM 332
Query: 781 HRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKS 840
R ++ + + E K + LE++ + + +IR Q E K + E K+ K
Sbjct: 333 RRQEEMMWEKEEKIRELEEKMHE-------QEKIREQEE-------KRQEEEKIREQEKR 378
Query: 841 KLHYKQQWGRALK-ELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQE 899
+ + W + K K REQE M +++ E E+ ++ K RQE
Sbjct: 379 QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQE 438
Query: 900 LLDIRNELNRLRQQEQK--QYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMR 957
IR + ++R+QE+K + ++ + K G + E+ ++E++ MR
Sbjct: 439 -EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ------EAKMQEQEEKMR 491
Query: 958 TGVYNHEDRIISELDRQIRE 977
++ I E +++IRE
Sbjct: 492 -----RQEEKIREQEKKIRE 506
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 69.7 bits (169), Expect = 1e-11
Identities = 89/347 (25%), Positives = 157/347 (45%), Gaps = 72/347 (20%)
Query: 642 QTEPRETLEYKAALELE-MWKEMQEDIFENQLKQKELAH-MQALAEEWKKRDRERESLVK 699
Q E L + LEL + E+++ I Q K L ++ L +K + E E L K
Sbjct: 2543 QVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELE-LTK 2601
Query: 700 -------KKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQ 752
+KV + T E +LQ+ ++ + Q+ A ++ EL EK L E Q L+E++
Sbjct: 2602 MDKMSFVEKVNKMTAKETELQR---EMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIK 2658
Query: 753 DSIRRAKE------------DCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKIL--- 797
S + KE DC+H+ ++E K ++ E+ Q +L++AE K++ L
Sbjct: 2659 SSKDQLKELTLENSELKKSLDCMHKDQVE--KEGKVREEIAEYQLRLHEAEKKHQALLLD 2716
Query: 798 -----EKEFQQFKDQQNNKPEIRLQS--EINLLTLEKVELERKLESATKSKLHYKQQWGR 850
E E Q ++++ +K E EI+LL K EL L++ T+ K+
Sbjct: 2717 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMD 2776
Query: 851 ALKELARLKQREQESQ--MARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELN 908
LK + +LK+ + +Q M L K ++LE EEK+ ++ EL+
Sbjct: 2777 NLKYVNQLKKENERAQGKMKLLIKSCKQLE---------EEKEI----------LQKELS 2817
Query: 909 RLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTL 955
+L+ ++KQ G+V++ +D+ T + E ++TL
Sbjct: 2818 QLQAAQEKQKT--------------GTVMDTKVDELTTEIKELKETL 2850
Score = 63.5 bits (153), Expect = 9e-10
Identities = 72/304 (23%), Positives = 140/304 (46%), Gaps = 27/304 (8%)
Query: 638 PSEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESL 697
P E + + R ++E K LE ++ Q + + QLK+ E H L + +RE E
Sbjct: 2292 PIEEEHQLRNSIE-KLRARLEADEKKQLCVLQ-QLKESE-HHADLLKGRVENLERELEIA 2348
Query: 698 ----------VKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRN 747
+ E L+ K++ L E + ++ SE + ELQ E++R
Sbjct: 2349 RTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQER- 2407
Query: 748 LQELQDSIRRAKEDCIHQVELERLKIKQLEEDK-HRLQQQLNDAENKYKILEKEFQQFKD 806
+ EL+ I + E+ + + E E++++K+ LQ QL + + L + + K
Sbjct: 2408 ISELE-IINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKA 2466
Query: 807 QQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQR--EQE 864
++ N L S++ L LEK +L + L+ A + + + ++E+ KQ+ +++
Sbjct: 2467 KEQN-----LSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKD 2521
Query: 865 SQMARLKKQQEELEQMRLRYLAAE-EKDTVKTERQELLDIRNELN---RLRQQEQKQYQD 920
+++RLK Q ++ EQ+ + E E K + EL ++ EL ++ Q + QD
Sbjct: 2522 EEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQD 2581
Query: 921 STEI 924
+ E+
Sbjct: 2582 TLEV 2585
Score = 63.2 bits (152), Expect = 1e-09
Identities = 72/281 (25%), Positives = 116/281 (41%), Gaps = 43/281 (15%)
Query: 661 KEMQEDIFENQLKQKELAHMQA-LAEEWKKRDRERESLVKKKV------AEYTILEGKLQ 713
KEM+ + + Q Q +L + L E+ K ++ R+ LV+ +YT LE KL+
Sbjct: 306 KEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLK 365
Query: 714 KTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKI 773
K DL + Q S L+++ KE + E Q L Q S + ++CI
Sbjct: 366 KLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQM-------- 417
Query: 774 KQLEEDKHRLQQQLNDAENKYKILEKEFQQF---KDQQNNKPE------IRLQSEINLLT 824
K RL Q+L A+N + +L+ E + K Q N E R +
Sbjct: 418 ------KARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQ 471
Query: 825 LEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRY 884
+++ EL R +E K LK + K RE A LK ++ L Q +
Sbjct: 472 IKENELRRSMEEMKKE--------NNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQ--- 520
Query: 885 LAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIA 925
AEE T ++ +L R+ ++ QQE + ++A
Sbjct: 521 NFAEEMKAKNTSQETML--RDLQEKINQQENSLTLEKLKLA 559
Score = 60.5 bits (145), Expect = 8e-09
Identities = 48/212 (22%), Positives = 102/212 (48%), Gaps = 25/212 (11%)
Query: 685 EEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSER 744
EEWK E L + + + LEG+L K + ++R+ QL S+E+ LQ++K+++++E+
Sbjct: 6 EEWK------EGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEK 59
Query: 745 ---------QRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYK 795
+ L E+ +S+ + K+ H+++++ ++ E QLN + + +
Sbjct: 60 TEGTNLKRENQRLMEICESLEKTKQKISHELQVKESQVNFQE-------GQLNSGKKQIE 112
Query: 796 ILEKEFQQFKDQQNNKPEIRLQSEINL---LTLEKVELERKLESATKSKLHYKQQWGRAL 852
LE+E ++ K + + ++++L T +K+ S S Y+ +
Sbjct: 113 KLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYN 172
Query: 853 KELARLKQREQESQMARLKKQQEELEQMRLRY 884
KE+ K+ E E + + KK + L Q + +
Sbjct: 173 KEVEERKRLEAEVKALQAKKASQTLPQATMNH 204
Score = 56.2 bits (134), Expect = 1e-07
Identities = 67/310 (21%), Positives = 137/310 (44%), Gaps = 40/310 (12%)
Query: 647 ETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYT 706
+T+ K ++ ++M+E E + Q E H +AE K E + V+E
Sbjct: 1968 DTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELL 2027
Query: 707 ILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQV 766
+ LQ+ L LEK Q L+ + EL+ + +L E++ ++E + R E ++
Sbjct: 2028 KDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKL 2087
Query: 767 ELER-------------LKIKQLEEDKHRL---------------QQQLNDAENKYKILE 798
+ + L++ +E+ H+L ++QL+ AE K K E
Sbjct: 2088 NVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAE-KLKERE 2146
Query: 799 KEFQQFKDQ-QNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALK---- 853
+E KD+ +N + E+++ E L + E + K+++ ++ R+LK
Sbjct: 2147 RENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQI---EEMARSLKVFEL 2203
Query: 854 ELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQ 913
+L L+ E+E+ +++++Q +L + L L + K ++ + Q + I+ E +
Sbjct: 2204 DLVTLRS-EKENLTKQIQEKQGQLSE--LDKLLSSFKSLLEEKEQAEIQIKEESKTAVEM 2260
Query: 914 EQKQYQDSTE 923
Q Q ++ E
Sbjct: 2261 LQNQLKELNE 2270
Score = 52.0 bits (123), Expect = 3e-06
Identities = 57/239 (23%), Positives = 117/239 (48%), Gaps = 21/239 (8%)
Query: 643 TEPRETLEYKAALELEMWKEMQEDIFENQLK--QKELAHMQALAEEWKKRDRERESLVKK 700
+E +++L+ ++E +++E+I E QL+ + E H L + K+ + E ++ +K
Sbjct: 2672 SELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREK 2731
Query: 701 KVAEYTILEGKLQKTLIDLEKR-EQQLASVESELQREKKELQSERQRNLQELQDSIRRAK 759
++ L QK IDL K +++L + + +EL+ + NL+ + + +++
Sbjct: 2732 LTSKEECLSS--QKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYV-NQLKKEN 2788
Query: 760 EDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSE 819
E +++L KQLEE+K LQ++L+ + Q+ K + ++
Sbjct: 2789 ERAQGKMKLLIKSCKQLEEEKEILQKELSQLQ-------------AAQEKQKTGTVMDTK 2835
Query: 820 INLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQ--ESQMARLKKQQEE 876
++ LT E EL+ LE TK Y ++ L +L++ ++ E+Q+A L QQ +
Sbjct: 2836 VDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAHLCSQQSK 2894
Score = 51.2 bits (121), Expect = 5e-06
Identities = 58/269 (21%), Positives = 129/269 (47%), Gaps = 33/269 (12%)
Query: 711 KLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELER 770
+L+ ++LE++ Q L S + LQ + LQS + + L++ + K D + VE
Sbjct: 2557 ELRNLTVELEQKIQVLQSKNASLQDTLEVLQS----SYKNLENELELTKMDKMSFVE--- 2609
Query: 771 LKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQ------SEINLLT 824
K+ ++ + LQ+++++ K L++E K++ + ++ L+ ++ LT
Sbjct: 2610 -KVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELT 2668
Query: 825 LEKVELERKLESATKSKLHYKQQWGRALKELA----RLKQREQESQMARL---KKQQEEL 877
LE EL++ L+ K ++ ++ G+ +E+A RL + E++ Q L K+ + E+
Sbjct: 2669 LENSELKKSLDCMHKDQV---EKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEI 2725
Query: 878 EQMRLRYLAAE--------EKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASG-K 928
+ R + + E E D +K+ ++EL + ++ ++ +K D+ + + K
Sbjct: 2726 QTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLK 2785
Query: 929 KDGPHGSVLEEGLDDYLTRLIEERDTLMR 957
K+ + L +L EE++ L +
Sbjct: 2786 KENERAQGKMKLLIKSCKQLEEEKEILQK 2814
Score = 46.6 bits (109), Expect = 1e-04
Identities = 87/427 (20%), Positives = 167/427 (39%), Gaps = 112/427 (26%)
Query: 609 KMREIFISDSSQGVSAVQQKPSSLPP--APCPSEIQTEPRETLEYKAALELEMWKEMQED 666
+M + F++++SQ +S +Q+ S+ A S ++ + +E +E E E+QE
Sbjct: 872 QMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQ-AEIQEL 930
Query: 667 IFENQLKQKELAHMQALAEEWKKRDRERESLV---KKKVAEYTILEGKLQKT-------- 715
N L + L +Q L+E +E S++ K+++ E T G L++
Sbjct: 931 KKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEK 990
Query: 716 -----------------------LIDLEKREQQLASVESELQREKKELQSERQRNLQELQ 752
L D K+E+ + E E S++ + QE
Sbjct: 991 MNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKN 1050
Query: 753 DSIRRAKEDCI-----HQVELERLK------------------------IKQLEEDKHRL 783
+ +C + ELE+LK + +LE + L
Sbjct: 1051 SKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQAL 1110
Query: 784 QQQLNDAENKYKI----LEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELER------- 832
+ ++ D +N K L++E K++QN ++Q E+N L E +L +
Sbjct: 1111 RSEMTDNQNNSKSEAGGLKQEIMTLKEEQN-----KMQKEVNDLLQENEQLMKVMKTKHE 1165
Query: 833 -------------KLESATKSKLHYKQQWGRALKEL------ARLKQREQESQMARLKKQ 873
K + +++ ++K Q +KE+ A+L Q E + LK Q
Sbjct: 1166 CQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQ 1225
Query: 874 QEELEQMRLRYLAAEEKDTVK--TERQELLDIRN-ELNRLR----QQEQKQYQDSTEIAS 926
+ E E+ L++ E T++ E L D+++ E++ L+ E+K E+++
Sbjct: 1226 ESEKEKECLQH----ELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHELST 1281
Query: 927 GKKDGPH 933
+ D H
Sbjct: 1282 SQNDNAH 1288
Score = 44.3 bits (103), Expect = 6e-04
Identities = 67/302 (22%), Positives = 127/302 (42%), Gaps = 38/302 (12%)
Query: 641 IQTEPRETLEYKAALE--LEMWKEM---QEDIFE-NQLKQKELAHMQALAEEWKKRDRER 694
+Q E + K LE LE +K+ E F+ +Q+K+ EL EE KK +
Sbjct: 435 LQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSM---EEMKKENNLL 491
Query: 695 ESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDS 754
+S ++K E LE +L K +Q + E K + ++ L++LQ+
Sbjct: 492 KSHSEQKAREVCHLEAEL--------KNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEK 543
Query: 755 IRRAKEDCIHQVELERLKIKQLEEDKHR------------LQQQLNDAENKYKILEKEFQ 802
I + + + + LE+LK+ + +K R +QLND +K + K
Sbjct: 544 INQQE----NSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALL 599
Query: 803 QFKDQQNNKPEIRLQSEINLLTLEKVELERKLE--SATKSKLHYKQQWGRALKELARLKQ 860
+ + + E L+ E L + K E E+ L + K L K + ++K
Sbjct: 600 SALELKKKEYE-ELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKS 658
Query: 861 REQESQMARLKKQQEEL--EQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQY 918
E ++ L+ +E L E L + + V+T++ ++++ + Q+ QK+
Sbjct: 659 HEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEI 718
Query: 919 QD 920
++
Sbjct: 719 EN 720
Score = 37.7 bits (86), Expect = 0.054
Identities = 38/158 (24%), Positives = 77/158 (48%), Gaps = 15/158 (9%)
Query: 760 EDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSE 819
++ IH ++L ++K+ + RL + D + K + L E ++ D + + E++L ++
Sbjct: 1766 QEDIHNLQL---RVKETSNENLRLLHVIEDRDRKVESLLNEMKEL-DSKLHLQEVQLMTK 1821
Query: 820 INL-LTLEKVELERKLESATKS-KLHYKQ-QWGRALKELARLKQREQESQMARLKKQQEE 876
I + LEK+ E K E++ S KL Y L+ + + + +M K +E+
Sbjct: 1822 IEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSRED 1881
Query: 877 LEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQE 914
+ A+ D+ K + LD+ NEL+R+R ++
Sbjct: 1882 IGDN-----VAKVNDSWK---ERFLDVENELSRIRSEK 1911
Score = 35.8 bits (81), Expect = 0.20
Identities = 25/91 (27%), Positives = 45/91 (49%), Gaps = 1/91 (1%)
Query: 652 KAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGK 711
+AAL+ + K E LK +E + + E +K ++ ++ K ++ EG+
Sbjct: 45 EAALQKQKQKVENEKTEGTNLK-RENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQ 103
Query: 712 LQKTLIDLEKREQQLASVESELQREKKELQS 742
L +EK EQ+L +SEL+R ++ QS
Sbjct: 104 LNSGKKQIEKLEQELKRCKSELERSQQAAQS 134
Score = 33.9 bits (76), Expect = 0.77
Identities = 48/205 (23%), Positives = 86/205 (41%), Gaps = 26/205 (12%)
Query: 650 EYKAALELEMWKEMQEDIFENQLKQ--KELAHMQALAEEWKKRDRERESLVKKKVAEYTI 707
E+K L +++QE E QL + KE Q + + ++++ V+ + E T
Sbjct: 7 EWKEGLPTRALQKIQE--LEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTN 64
Query: 708 LEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVE 767
L+ + Q+ + E E+ + ELQ E Q N QE Q + + + + + Q E
Sbjct: 65 LKRENQRLMEICESLEKTKQKISHELQ------VKESQVNFQEGQLNSGKKQIEKLEQ-E 117
Query: 768 LERLKIKQLEEDKHRLQQ---QLNDAENKYKILE-----------KEFQQFKDQQNNKPE 813
L+R K +LE + Q LN KI +++ K++ N + E
Sbjct: 118 LKRCK-SELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVE 176
Query: 814 IRLQSEINLLTLEKVELERKLESAT 838
R + E + L+ + + L AT
Sbjct: 177 ERKRLEAEVKALQAKKASQTLPQAT 201
Score = 33.1 bits (74), Expect = 1.3
Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 846 QQWGRALKELARLKQREQESQMARLK--KQQEELEQMRLRYLAAEEKDTVKTERQELLDI 903
++W L A K +E E Q+ +LK KQQ + + L ++K V+ E+ E ++
Sbjct: 6 EEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNL 65
Query: 904 RNELNRLRQ 912
+ E RL +
Sbjct: 66 KRENQRLME 74
Score = 32.3 bits (72), Expect = 2.2
Identities = 70/325 (21%), Positives = 131/325 (40%), Gaps = 42/325 (12%)
Query: 626 QQKPSSLPPAPCPSEIQTEPRETLEYKAALELEM-WKEMQEDIFENQLKQKELAHMQALA 684
+Q P SL P E + TL K E++M + E+QE Q + K L
Sbjct: 1375 EQHPVSLAPL---DESNSYEHLTLSDK---EVQMHFAELQEKFLSLQSEHKILHDQHC-- 1426
Query: 685 EEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQ------LASVESELQREKK 738
+ + E ++ V AE +L L+ DL K Q + S+ S +
Sbjct: 1427 -QMSSKMSELQTYVDSLKAENLVLSTNLRNFQGDLVKEMQLGLEEGLVPSLSSSCVPDSS 1485
Query: 739 ELQSERQRN-----LQELQD-SIRRAKEDCI--HQVELERLKIKQLEEDKHRLQQQLNDA 790
L S + L++ D S+ E + +Q ++ + L+E+ ++ +
Sbjct: 1486 SLSSLGDSSFYRALLEQTGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAP 1545
Query: 791 ENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESAT-------KSKLH 843
+ LE + ++ Q K E +++S+ + E ELE+ L S K L
Sbjct: 1546 AKGVEELESLCEVYR-QSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLS 1604
Query: 844 YKQQWGRALKELARLKQREQESQMARLKKQQEELE------QMRLRYLAAEEKDTVKTER 897
+QW + L + E ES++A KKQ E+L +++L+ L + + +
Sbjct: 1605 ENEQWQQKLTSVTL----EMESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLLGIDT 1660
Query: 898 QELLDIRNELNRLRQQEQKQYQDST 922
++ + RNE + ++ + + T
Sbjct: 1661 EDAIQGRNESCDISKEHTSETTERT 1685
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 69.7 bits (169), Expect = 1e-11
Identities = 66/307 (21%), Positives = 143/307 (46%), Gaps = 36/307 (11%)
Query: 640 EIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVK 699
E+ R E K ALE E+ E + E Q ++ ++ +E ++ R LV+
Sbjct: 185 ELSRRSRSDAETKRALE-----ELTEKLNEAQKQEVVSDRVERRLQELEREMRTERELVE 239
Query: 700 KKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRR-- 757
++ + ++ +LQ+ L +K+E + E ++ + ++ ++E+ + QEL+ S R
Sbjct: 240 RRQDQLGLMSLQLQEAL---KKQEAKADEHEGAIKNKLRQTETEKNQLEQELELSRRLLN 296
Query: 758 ----AKEDCIHQVELERLKIKQLEEDKHRLQQQLNDA---ENKYKILEKEFQQFK----- 805
++E +HQVE R ++ + E D+ LQ Q++ ++ Y+ + E +F+
Sbjct: 297 QSEGSRETLLHQVEELRTQLTKAEGDRKGLQHQVSQISKQQSNYQDEQGEDWRFRRGVER 356
Query: 806 ---DQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQRE 862
D + ++R+Q + + E E++R +E K K H Q +EL +++
Sbjct: 357 EKQDLEKQMSDLRVQLNFSAMASELEEVKRCMERKDKEKAHLASQVENLTRELEN-GEKQ 415
Query: 863 QESQMARLKKQQEELE---------QMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQ 913
Q + RLK+ Q + +++ L +D K + L +++ + L+++
Sbjct: 416 QLQMLDRLKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAERYLSELQ-QSEALKEE 474
Query: 914 EQKQYQD 920
+K+ +D
Sbjct: 475 AEKRRED 481
Score = 63.2 bits (152), Expect = 1e-09
Identities = 58/265 (21%), Positives = 130/265 (49%), Gaps = 31/265 (11%)
Query: 676 ELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQR 735
EL +AL EE +KR + + ++ + ++ + KL++ L + +L +++ +
Sbjct: 464 ELQQSEALKEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILK 523
Query: 736 EKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYK 795
EK EL+++ LQ++ +++R+ D + + L+ EE+ H +++L D ++
Sbjct: 524 EKDELKTQLYAALQQI-ENLRKELNDVLTKRALQ-------EEELHSKEEKLRDIKSHQA 575
Query: 796 ILEKEFQQFKDQQNN-KPEIRLQSEI-NLLTLEKVELERKLESATKSKLHYKQ---QWGR 850
LE E + D + + E++ QS+I + + +EK LE ++ KS+ K +
Sbjct: 576 DLELEVKNSLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKLLEMQE 635
Query: 851 ALKELARLK-------QREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTE------- 896
++K+L+ ++ E+ ++ A LK + Q + R EE T+ T+
Sbjct: 636 SIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSR---DEETATIITQLKLERDV 692
Query: 897 -RQELLDIRNELNRLRQQEQKQYQD 920
++EL D+ + L ++ + ++ Q+
Sbjct: 693 HQRELKDLTSSLQSVKTKHEQNIQE 717
Score = 56.2 bits (134), Expect = 1e-07
Identities = 75/327 (22%), Positives = 145/327 (44%), Gaps = 62/327 (18%)
Query: 644 EPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVA 703
E +E+++ +A+ ++ ++ E E + K+ L + L + K RD E +++ +
Sbjct: 632 EMQESIKDLSAIRADLANKLAE---EERAKKAVLKDLSDLTAQAKSRDEETATIITQLKL 688
Query: 704 EYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCI 763
E + Q+ L DL L SV+++ ++ +EL ++ E ++ IR K + +
Sbjct: 689 ERDVH----QRELKDLTS---SLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTLKAESL 741
Query: 764 HQVELERLKIKQLEEDKH---RLQQQLNDAENKYKILEKEFQQFKDQQNNK--------- 811
+ + ++ QLE+ K RL ++L EN+ K L+ ++Q KDQ +
Sbjct: 742 EEKNMAKIHRGQLEKLKSQCDRLTEELTQNENENKKLKLKYQCLKDQLEEREKHISIEEE 801
Query: 812 -----PEIRLQSEINLLTLEKVE------LERKLESATKS----------------KLHY 844
E RLQ + LL LE + + +++++A K+ +HY
Sbjct: 802 HLRRMEEARLQLKDQLLCLETEQESILGVIGKEIDAACKTFSKDSVEKLKVFSSGPDIHY 861
Query: 845 -KQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDI 903
+W LA K + Q LK+++ + +R + + ++ TE +E
Sbjct: 862 DPHRW------LAESKTKLQ-WLCEELKERENREKNLRHQLMLCRQQLRNLTENKE---- 910
Query: 904 RNELNRLRQQEQKQYQDSTEIASGKKD 930
+EL L QQ ++Q Q EI K+D
Sbjct: 911 -SELQCLFQQIERQEQLLDEIHREKRD 936
Score = 43.5 bits (101), Expect = 0.001
Identities = 53/263 (20%), Positives = 112/263 (42%), Gaps = 46/263 (17%)
Query: 670 NQLKQKELAHMQALAEEWKKR---DRERESLVKKKV-----AEYTILEGKLQKTLIDLEK 721
+Q+ +++ + E+W+ R +RE++ L K+ ++ + +L++ +E+
Sbjct: 331 SQISKQQSNYQDEQGEDWRFRRGVEREKQDLEKQMSDLRVQLNFSAMASELEEVKRCMER 390
Query: 722 REQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKH 781
++++ A + S+++ +EL++ ++ LQ L +RLK Q D
Sbjct: 391 KDKEKAHLASQVENLTRELENGEKQQLQML-----------------DRLKEIQNHFDTC 433
Query: 782 RLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSK 841
+AE K+ L+ + K R SE+ K E E++ E
Sbjct: 434 -------EAERKHADLQISELTRHAEDATKQAERYLSELQQSEALKEEAEKRREDLKLKA 486
Query: 842 LHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTE----R 897
+QW K+L R +++ E+ K + L +EKD +KT+
Sbjct: 487 QESIRQWKLKHKKLERALEKQSETVDELTGKNNQIL----------KEKDELKTQLYAAL 536
Query: 898 QELLDIRNELNRLRQQEQKQYQD 920
Q++ ++R ELN + + Q ++
Sbjct: 537 QQIENLRKELNDVLTKRALQEEE 559
Score = 42.7 bits (99), Expect = 0.002
Identities = 65/319 (20%), Positives = 143/319 (44%), Gaps = 36/319 (11%)
Query: 689 KRDRERESL-VKKKVAEYTILEGKLQKTLIDLEKREQQLAS-VESELQREKKELQSERQR 746
KR R R + ++ + T L G ++L DL + +L EL R + +E +R
Sbjct: 141 KRMRSRTGVRFVQETDDMTQLHG-FHQSLRDLSSEQIRLGDDFNRELSRRSRS-DAETKR 198
Query: 747 NLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKD 806
L+EL + + A++ + +ER ++++LE + ++ + +++ ++ + Q+
Sbjct: 199 ALEELTEKLNEAQKQEVVSDRVER-RLQELEREMRTERELVERRQDQLGLMSLQLQEALK 257
Query: 807 QQNNKP---EIRLQSEINLLTLEKVELERKL----------ESATKSKLHYKQQWGRALK 853
+Q K E +++++ EK +LE++L E + ++ LH ++ L
Sbjct: 258 KQEAKADEHEGAIKNKLRQTETEKNQLEQELELSRRLLNQSEGSRETLLHQVEELRTQLT 317
Query: 854 ELARLKQREQESQMARLKKQQ-----EELEQMRLRYLAAEEKDTVKTERQEL------LD 902
+ A ++ + Q++++ KQQ E+ E R R EK ++ + +L
Sbjct: 318 K-AEGDRKGLQHQVSQISKQQSNYQDEQGEDWRFRRGVEREKQDLEKQMSDLRVQLNFSA 376
Query: 903 IRNELNRLRQQEQKQYQDSTEIASG----KKDGPHGSVLEEGLDDYLTRLIEERDTLMRT 958
+ +EL +++ +++ ++ +AS ++ +G + + D L + DT
Sbjct: 377 MASELEEVKRCMERKDKEKAHLASQVENLTRELENGEKQQLQMLDRLKEIQNHFDTC--E 434
Query: 959 GVYNHEDRIISELDRQIRE 977
H D ISEL R +
Sbjct: 435 AERKHADLQISELTRHAED 453
Score = 40.4 bits (93), Expect = 0.008
Identities = 100/507 (19%), Positives = 207/507 (40%), Gaps = 88/507 (17%)
Query: 490 MTNPPVEVRKNMEVFLPQSYCAFD-FATMPHQLQDTFLRIPLLVELWH-KDKMSKDLLLG 547
+T ++ K + Q Y A + +L D + L E H K++ +D+
Sbjct: 514 LTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEELHSKEEKLRDIKSH 573
Query: 548 IARIQLSNILSSEKTRFLGSNGEQCWRQTYSESVPVIAAQGSNNRIADLSYTVTLEDYGL 607
A ++L S + L S + +Q+ +S + IA+L + + L
Sbjct: 574 QADLELEVKNSLDTIHRLES---ELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKL 630
Query: 608 VKMREIF-------------ISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAA 654
++M+E +++ + AV + S L ++ + E T+ +
Sbjct: 631 LEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLT---AQAKSRDEETATIITQLK 687
Query: 655 LELEMWKEMQEDIFEN--QLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYT------ 706
LE ++ + +D+ + +K K ++Q L + +KK E E+ ++ AE
Sbjct: 688 LERDVHQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTLKAESLEEKNMA 747
Query: 707 -ILEGKLQKTLIDLEKREQQLASVESELQREKKELQ------SERQRNLQELQDSIRRAK 759
I G+L+K ++ ++L E+E ++ K + Q ER++++ ++ +RR +
Sbjct: 748 KIHRGQLEKLKSQCDRLTEELTQNENENKKLKLKYQCLKDQLEEREKHISIEEEHLRRME 807
Query: 760 ED---------CIHQVE----------------------LERLKI----KQLEEDKHRLQ 784
E C+ + +E+LK+ + D HR
Sbjct: 808 EARLQLKDQLLCLETEQESILGVIGKEIDAACKTFSKDSVEKLKVFSSGPDIHYDPHRWL 867
Query: 785 QQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHY 844
AE+K K L+ ++ K+++N + +R Q L L + +L R L +S+L
Sbjct: 868 -----AESKTK-LQWLCEELKERENREKNLRHQ-----LMLCRQQL-RNLTENKESELQC 915
Query: 845 KQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIR 904
Q ++L RE+ + +++ EE+ ++ R +A E V + E +
Sbjct: 916 LFQQIERQEQLLDEIHREKRDLLEETQRKDEEMGSLQDRVIALETSTQVALDHLE--SVP 973
Query: 905 NELNRLRQQEQKQYQDSTEIASGKKDG 931
+L+ L ++ K ++DS +S + DG
Sbjct: 974 EKLSLL--EDFKDFRDSCS-SSERTDG 997
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 69.3 bits (168), Expect = 2e-11
Identities = 92/403 (22%), Positives = 182/403 (45%), Gaps = 62/403 (15%)
Query: 612 EIFISDSSQGVSAVQQK-PSSLPPAPCPSEIQTEPRETLEYKAALELEMWKEMQEDIFEN 670
EI ++D+ + + +Q SL P + + E L+ + LELE+ ++I+E
Sbjct: 651 EISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQI-LELELNFHKAQEIYEK 709
Query: 671 QL--KQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLAS 728
L K KE++++ L EE+KK S +T L E+R+Q L+
Sbjct: 710 NLDEKAKEISNLNQLIEEFKKNADNNSSA-------FTALS----------EERDQLLSQ 752
Query: 729 VE-----SELQREKKELQ-----SERQRNLQ-ELQDSIRRAKEDCIHQVELERLKIKQLE 777
V+ +EL+ + K+L+ +ERQR L E Q + + IH + +E K +
Sbjct: 753 VKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEA---KSKD 809
Query: 778 EDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESA 837
LQ +L+D + ++ + + Q NK +SE+ LE E R + S
Sbjct: 810 VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNK-----ESEV----LEGAERVRHISSK 860
Query: 838 TKS---KLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAA-----EE 889
+ L K+ + +L K+R+ E+ ++++ +++ ++ EE
Sbjct: 861 VEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEE 920
Query: 890 KDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKD-----GPHGSVLEEGLD-- 942
K ++ E + L + N L+R + +++Q ++ E++SG K P G + +E L
Sbjct: 921 KFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHE 980
Query: 943 -DYLTRLIEERDTLMRTGVYNHEDRI--ISELDRQIREILAKS 982
D L + E+R ++ + N ++ + +S L+ ++ + +S
Sbjct: 981 FDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDES 1023
Score = 64.7 bits (156), Expect = 4e-10
Identities = 103/442 (23%), Positives = 203/442 (45%), Gaps = 73/442 (16%)
Query: 574 RQTYSESVPVIAAQGSNNRIA-DLSYTVTLEDYGLVKMREIF-ISDSSQGVSAVQQKPSS 631
R T SESVP +A+ +N ++ D S + +Y +++I + + G+ +QK
Sbjct: 1808 RPTCSESVP--SAKSANPAVSKDFSSHDEINNY----LQQIDQLKERIAGLEEEKQKNKE 1861
Query: 632 LPPAPCPSEIQTEPRETLEYKAALELEMWKEMQEDIFE----NQLKQKELAHMQALAEEW 687
S+ + TL + + + K +QE++ + NQ Q+EL+ + L E
Sbjct: 1862 F------SQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETA 1915
Query: 688 KKRDRERESLVKKKVAEYTILEGKLQKTLID-------LEKREQQLASVESELQREKKEL 740
++ + E + ++AE G + + D LE + L SEL+ EK++L
Sbjct: 1916 EEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQL 1975
Query: 741 QSERQRNLQELQ----DSIRRAKED---CIHQVELERL------KIKQLEEDKHRLQQQL 787
E+ + E++ + I+ A+++ H EL+ L ++KQL++D R Q+++
Sbjct: 1976 VKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKI 2035
Query: 788 NDAENKYKILE-------KEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKS 840
+ E K LE K+ + K+ E R +++ L + + + + + E+A
Sbjct: 2036 SALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAA--- 2092
Query: 841 KLHYKQQWGRALKELARLK---QREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTER 897
R L + +LK Q +ES +++K++ E+LE+ R AEEK
Sbjct: 2093 ---------RVLADNLKLKKELQSNKESVKSQMKQKDEDLER---RLEQAEEK-----HL 2135
Query: 898 QELLDIRNELNRLRQQE--QKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTL 955
+E +++ +L+ LR+++ ++ ++ KKD L+E LD +T+L T
Sbjct: 2136 KEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD-KEVQQLQENLDSTVTQL--AAFTK 2192
Query: 956 MRTGVYNHEDRIISELDRQIRE 977
+ + + DR+I E + R+
Sbjct: 2193 SMSSLQDDRDRVIDEAKKWERK 2214
Score = 57.4 bits (137), Expect = 7e-08
Identities = 66/282 (23%), Positives = 124/282 (43%), Gaps = 38/282 (13%)
Query: 671 QLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVE 730
++ Q EL +Q E R +S ++ K +E +LEG + I + E A +
Sbjct: 813 EVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESE--VLEGAERVRHISSKVEELSQALSQ 870
Query: 731 SELQREKKE-LQSERQRNLQELQDSIRRAKEDCIHQVELERL-KIKQLEEDKHRLQQQLN 788
EL+ K + L E++R+++ LQ +I K+ + ++ K+ QL E+K L ++
Sbjct: 871 KELEITKMDQLLLEKKRDVETLQQTIEE-KDQQVTEISFSMTEKMVQLNEEKFSLGVEIK 929
Query: 789 DAENKYKILEKEFQQFKDQQNNKPEI--------------------RLQSEINLLTLEKV 828
+ + +L + + K+Q E+ LQ E +LL E
Sbjct: 930 TLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENE 989
Query: 829 ELERKLESATKSKLHYKQQWGRALKELARLKQREQ------ESQMARLKKQQEELE---- 878
+ +RKL++A ++ Q+ R +ELA LK + E++ +++ +E E
Sbjct: 990 QRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEK 1049
Query: 879 --QMRLRYLAAEEKDTVKTERQELLDIRNEL-NRLRQQEQKQ 917
+ + + K T+ + EL IR +L +L +EQ Q
Sbjct: 1050 CVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQ 1091
Score = 57.0 bits (136), Expect = 9e-08
Identities = 80/373 (21%), Positives = 172/373 (46%), Gaps = 56/373 (15%)
Query: 574 RQTYSESVPVIAAQGSNNRIADLSYTVTLEDYGLVKMREIFISDSSQGVSAVQQKPSSLP 633
R+ Y E + QG+ + S+ L++ L+K ++ + + Q+K S+L
Sbjct: 1987 RKEYLEKI-----QGAQKEPGNKSHAKELQE--LLKEKQQEVKQLQKDCIRYQEKISAL- 2038
Query: 634 PAPCPSEIQTEPRETLEYKAALELEMWKEMQEDIFENQLK-QKELAHMQALAEEWKKRDR 692
E + E ++ ++ +LE+ KE E++ K Q ELA + L ++
Sbjct: 2039 ------ERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDD------ 2086
Query: 693 ERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQR---EKKELQSERQRNLQ 749
+S + +A+ L+ +LQ + E + Q+ + +L+R + +E + ++N+Q
Sbjct: 2087 -TQSEAARVLADNLKLKKELQS---NKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQ 2142
Query: 750 ELQDSIRRAK---EDCIHQVELERLK----IKQLEEDKHRLQQQL-----------NDAE 791
E D++RR K E+ I ++++ K ++QL+E+ QL +D +
Sbjct: 2143 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRD 2202
Query: 792 NKYKILEKEFQQFKDQ-QNNKPEIRLQSE---INLLTLEKVELERKLESATKSKL-HYKQ 846
+K ++F D Q+ + EIRL+ + + L ++ + + S+L H KQ
Sbjct: 2203 RVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQ 2262
Query: 847 QWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEE-----KDTVKTERQELL 901
W + +L+Q+ ++ K+ +LE+ R Y +++ + +K+ + +L
Sbjct: 2263 IWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLT 2322
Query: 902 DIRNELNRLRQQE 914
D+ N L + ++Q+
Sbjct: 2323 DLSNSLEKCKEQK 2335
Score = 53.1 bits (126), Expect = 1e-06
Identities = 90/395 (22%), Positives = 164/395 (41%), Gaps = 61/395 (15%)
Query: 602 LEDYGLVKMREI---------FISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYK 652
L+ GL +RE+ IS + VS + + S A ++IQTE E +
Sbjct: 1379 LQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAAL--TKIQTEIIEQEDLI 1436
Query: 653 AALELEMWKEMQEDIFENQLKQK--ELAHMQALAEEWKKRDRERESLVKKKVAEYTILEG 710
AL ++ EMQ + ++KQ EL M+ EE + R ++ + +K
Sbjct: 1437 KALHTQL--EMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRK---------- 1484
Query: 711 KLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELER 770
LQ LI ++ ++ S++ EL + ++ ++L +++ + ++ L R
Sbjct: 1485 -LQAALISRKEALKENKSLQEELSLARGTIE-RLTKSLADVESQVSAQNKE--KDTVLGR 1540
Query: 771 LKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVEL 830
L + Q E DK I E + ++Q + L+ + LT +K +L
Sbjct: 1541 LALLQEERDK--------------LITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKL 1586
Query: 831 ERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEK 890
+++ES SK+ +W KEL Q+E E + + E E R++++
Sbjct: 1587 VKEIESLKSSKIAESTEWQEKHKEL----QKEYEILLQSYENVSNEAE--RIQHVV---- 1636
Query: 891 DTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIE 950
+ V+ E+QEL +++ +KQ Q++ + K+ + + L E
Sbjct: 1637 EAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMR--KFAKSKQQKILELEE 1694
Query: 951 ERDTLMRTGVYNHEDRIISELDRQIREILAKSNAS 985
E D L R V+ D ++ E L SNAS
Sbjct: 1695 ENDRL-RAEVHPAGDTA-----KECMETLLSSNAS 1723
Score = 51.6 bits (122), Expect = 4e-06
Identities = 73/343 (21%), Positives = 151/343 (44%), Gaps = 36/343 (10%)
Query: 654 ALELEMWKEMQEDIFENQLKQKELAHMQALAEEW-----KKRDRERESLVKKKVAEYTIL 708
AL +M + +Q+ + L Q E++ QA+ ++ D + +LVK+ V
Sbjct: 1092 ALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPC 1151
Query: 709 EGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVEL 768
G + +LE++ L + +LQ++ +E + R+ L++ Q+ R +E+
Sbjct: 1152 TGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREE------- 1204
Query: 769 ERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKV 828
+KQ ++D +RLQ+Q ++ + + + + +Q + Q + +L S +
Sbjct: 1205 ----LKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSST 1260
Query: 829 E-LERKLESATKSKLHYKQ---------QWGRALKELARLKQREQESQM-ARLKKQQEEL 877
LE L AT+ H+ Q W ++ + L+ +Q+ A+LK+ + E
Sbjct: 1261 PGLEEPLFKATEQ--HHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEK 1318
Query: 878 EQMRLRYLAAEEKDTVKTERQELLDIRNELNR--LRQQEQKQYQDSTEI-ASGKKDGPHG 934
++ L+ + + T K+E E+ ++ ++N+ L + K E+ A +
Sbjct: 1319 VELELKVSSTTSELTKKSE--EVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLES 1376
Query: 935 SVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIRE 977
S L+ ++L L + D L + ED +S L Q+ E
Sbjct: 1377 SQLQIAGLEHLRELQPKLDELQKLISKKEED--VSYLSGQLSE 1417
Score = 51.2 bits (121), Expect = 5e-06
Identities = 73/295 (24%), Positives = 141/295 (47%), Gaps = 39/295 (13%)
Query: 642 QTEPRETLEYKAALELEMWKEM--QEDIFENQLKQKELAHMQALAEEWKKRDRERESLVK 699
Q + +E L Y L +E+ K++ Q+D+ QL+QK+ +AL EE K D + + L
Sbjct: 47 QEDVQERLAYAEQLVVEL-KDIIRQKDV---QLQQKD----EALQEERKAADNKIKKLKL 98
Query: 700 KKVAEYTILEGKLQK------TLIDLEKR-EQQLA-----SVESELQREK-KELQSERQR 746
A+ T L +++ T++ E + E+QL+ S E E++ EK K E++
Sbjct: 99 HAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEE 158
Query: 747 NLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKD 806
+ LQ + +A+ + Q E E+ ++QQL + E L+ + Q +
Sbjct: 159 LISTLQAQLTQAQAEQPAQSSTEM-------EEFVMMKQQLQEKEEFISTLQAQLSQTQA 211
Query: 807 QQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQ 866
+Q + +R + + T ++ + L+ T++ + + Q + L+ L R + +ES
Sbjct: 212 EQAAQQVVR-EKDARFETQVRLHEDELLQLVTQADVETEMQ--QKLRVLQRKLEEHEESL 268
Query: 867 MARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDS 921
+ R Q +L Q L AAE+++ + + Q+L + E N LR + + ++S
Sbjct: 269 VGRA--QVVDLLQQELT--AAEQRNQILS--QQLQQMEAEHNTLRNTVETEREES 317
Score = 50.4 bits (119), Expect = 8e-06
Identities = 60/276 (21%), Positives = 134/276 (48%), Gaps = 26/276 (9%)
Query: 658 EMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLI 717
E+ +++E Q ELA +++ + K + + + ++K + LEG +++
Sbjct: 2288 ELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2347
Query: 718 DLEKREQQLASVESELQREKKELQS--ERQRNLQELQ-DSIRRAKEDCIHQVELERLKIK 774
D++ + +E++LQ +EL S + N++E + S+ KE+ I QV + L+ +
Sbjct: 2348 DIQNSKFSYEQLETDLQ-ASRELTSRLHEEINMKEQKIISLLSGKEEAI-QVAIAELR-Q 2404
Query: 775 QLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKL 834
Q +++ L+ L+ E + +LE+E ++ D+ N +L + + E ++ + +L
Sbjct: 2405 QHDKEIKELENLLSQEEEENIVLEEENKKAVDKTN-----QLMETLKTIKKENIQQKAQL 2459
Query: 835 ESATKSKLHYKQQWGRALKELARLKQRE-----QESQM-----ARLKKQQEELEQMRLRY 884
+S KS + R + + +L++R ++ Q+ A K +EE+ +R +
Sbjct: 2460 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLR-SH 2518
Query: 885 LAAEEKDTVKTERQELLDIRNELNR---LRQQEQKQ 917
+ + K + EL+ R +LN+ ++ +QKQ
Sbjct: 2519 MDDLNSENAKLD-AELIQYREDLNQVITIKDSQQKQ 2553
Score = 49.7 bits (117), Expect = 1e-05
Identities = 59/287 (20%), Positives = 134/287 (46%), Gaps = 27/287 (9%)
Query: 670 NQLKQKELAHMQALAE--EWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLA 727
++LK+K A ++ LA+ E +RER++L+ + E + +L LEK QQL
Sbjct: 2755 DELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTE---ENSLSHLEKLNQQLL 2811
Query: 728 SVESELQREKKELQS--ERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQ 785
S + +L +L+ + ++ + S++ ++ +++E K ++ EE K R
Sbjct: 2812 SKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELE----KFRKSEEGKQRSAA 2867
Query: 786 QLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLES--ATKSKLH 843
Q + + + + L+K ++ ++ RL E+ L + +++ +++ K++L
Sbjct: 2868 QPSTSPAEVQSLKKAMSSLQNDRD-----RLLKELKNLQQQYLQINQEITELHPLKAQLQ 2922
Query: 844 YKQQWGRALKEL-ARLKQR----EQESQMARLKKQQEELEQMRLR---YLAAEEKDTVKT 895
Q +A + + L+Q + E R++K E+ + R++ +A +KD +
Sbjct: 2923 EYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLS 2982
Query: 896 ERQELL-DIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGL 941
Q L+ ++R+ ++ + + + + ++ S DG V E L
Sbjct: 2983 HLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETEL 3029
Score = 49.3 bits (116), Expect = 2e-05
Identities = 75/351 (21%), Positives = 155/351 (44%), Gaps = 41/351 (11%)
Query: 650 EYKAALELEMWKEMQEDIFENQLKQKEL----AHMQALAEEWKKRDRERESLVKKKVAEY 705
E ++ LE + +QE EN ++E+ +HM L E K D E ++ + +
Sbjct: 2485 ERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQY-REDLNQV 2543
Query: 706 TILEGKLQKTLIDLE-KREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIH 764
++ QK L++++ ++ ++L + ++L+ + KE E +L+ ++++ K+D
Sbjct: 2544 ITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKE-SEEANEDLRRSFNALQEEKQDLSK 2602
Query: 765 QVELERLKIKQLEEDKHRLQQQ--LNDAENKYKILEKEFQQFKD--QQNNKPEIRLQSEI 820
++E ++ I QL LQ++ L + K+ E+E + + K L+ E+
Sbjct: 2603 EIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEEL 2662
Query: 821 NLLTLEKVELERKLESATKSKL-HYKQQWGRALKELARLKQREQESQMARLKKQQEELEQ 879
+ E + ++E K +L H G + R + E ++A L + E+EQ
Sbjct: 2663 VCVQKEAAKKVGEIEDKLKKELKHLHHDAG-----IMRNETETAEERVAELARDLVEMEQ 2717
Query: 880 MRLRYLAAEEKDTVKTE-----RQELLDIRNELNRLRQQEQKQYQDS-TEIASGKKDGPH 933
L + T + + L + R+ N + +++Y S E+A K
Sbjct: 2718 KLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLK----- 2772
Query: 934 GSVLEEGLDDYLTRLIEERDTLMRTGVY---NHEDRIISELDRQIREILAK 981
E+GL L ERD L+ + + E+ +S L++ +++L+K
Sbjct: 2773 ----EQGL------LNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSK 2813
Score = 48.5 bits (114), Expect = 3e-05
Identities = 61/272 (22%), Positives = 115/272 (42%), Gaps = 59/272 (21%)
Query: 625 VQQKPSSLPPAPCPSEIQTEPRETLEYKAALELE----MWKEMQEDIFENQ-----LKQK 675
+++ SL Q + ++T+ + AL E + EM + ENQ +
Sbjct: 1513 IERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESL 1572
Query: 676 ELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQR 735
+LA ++ L E+ +K +E ESL K+AE T + K ++ + E Q +V +E +R
Sbjct: 1573 KLA-LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAER 1631
Query: 736 ----------EKKEL----------QSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQ 775
EK+EL + E ++ LQE + + KE + ++ KI +
Sbjct: 1632 IQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILE 1691
Query: 776 LEEDKHRLQQQLNDAEN-------------------------KYKILEKEFQQFKDQQNN 810
LEE+ RL+ +++ A + +Y+ L K+FQ ++++
Sbjct: 1692 LEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDS 1751
Query: 811 KPE----IRLQSEINLLTLEKVELERKLESAT 838
E ++ Q E N+ +E K ++ T
Sbjct: 1752 LSEEVQDLKHQIEGNVSKQANLEATEKHDNQT 1783
Score = 43.9 bits (102), Expect = 7e-04
Identities = 67/305 (21%), Positives = 133/305 (43%), Gaps = 51/305 (16%)
Query: 646 RETLEYKAALELEMWKEMQEDIFENQLK----QKELAHMQALAEEWKKRDRERESLV--- 698
R T+E + + ++M+ ++ E +L Q+E+ H+ E+ + E ES
Sbjct: 307 RNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSAL 366
Query: 699 ----KKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDS 754
K ++ E T LQKT +L+ L S+L ++K E + + +Q+L+D
Sbjct: 367 EQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQ 426
Query: 755 IRRAKEDCIHQVELERLKIKQ--------------------LEEDKHRLQQQLNDAENKY 794
+++ ++ I Q L RL ++Q EE+ LQ+++ + EN+
Sbjct: 427 LQQKSKE-ISQF-LNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEK 484
Query: 795 KIL---EKEFQQFKDQQNNKPEIRLQSEINLLTLEK--VELERK------LESATKSKLH 843
L E ++ K + +L S+I LL + E +R+ ++ A K
Sbjct: 485 GALLLSSIELEELKAENE-----KLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSS 539
Query: 844 YKQQWGRALKELARLKQREQESQMARLKKQQEELE--QMRLRYLAAEEKDTVKTERQELL 901
++ L+ K +E + +K+ QEE+ +++L+ AEE D +++E+
Sbjct: 540 AEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMK 599
Query: 902 DIRNE 906
+ E
Sbjct: 600 QMEGE 604
Score = 41.2 bits (95), Expect = 0.005
Identities = 51/260 (19%), Positives = 111/260 (42%), Gaps = 49/260 (18%)
Query: 718 DLEKREQQLASVESELQREKK-ELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQL 776
D + + A ++ EL +E E + Q ++QE + A++ + ++ R K QL
Sbjct: 19 DDDTDQNMRAPLDPELHQESDMEFNNTTQEDVQE---RLAYAEQLVVELKDIIRQKDVQL 75
Query: 777 EEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLES 836
++ LQ++ A+NK K +++L ++ L +L K E K +
Sbjct: 76 QQKDEALQEERKAADNKIK-----------------KLKLHAKAKLTSLNKYIEEMKAQG 118
Query: 837 AT--KSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELE------QMRLRYLAAE 888
T ++ ++Q + K E+E ++ ++K + +E E Q +L AE
Sbjct: 119 GTVLPTEPQSEEQLSKHDK-----SSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAE 173
Query: 889 EKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRL 948
+ TE +E + ++ +L QE++++ + + + + + ++
Sbjct: 174 QPAQSSTEMEEFVMMKQQL-----QEKEEFISTLQ----------AQLSQTQAEQAAQQV 218
Query: 949 IEERDTLMRTGVYNHEDRII 968
+ E+D T V HED ++
Sbjct: 219 VREKDARFETQVRLHEDELL 238
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 69.3 bits (168), Expect = 2e-11
Identities = 97/353 (27%), Positives = 168/353 (47%), Gaps = 55/353 (15%)
Query: 641 IQTEPRETLEYKAALELEMW----KEMQEDIFENQL-------KQKELAHMQALAEEWKK 689
++ + RE E KA E E W +E+QE ++ QL KQ+EL + EE ++
Sbjct: 386 MEQQQREA-ERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQR---EEERR 441
Query: 690 RDRERESLVKKKVAEYTILEGKL--QKTLIDLEKREQQ----LASVESELQREKKELQSE 743
+D ER K+++ LE + ++ L++ + REQ+ L S + L E + L +
Sbjct: 442 KDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGK 501
Query: 744 RQRNLQELQDSIRRAK-------EDCIHQVELERLKIKQLEEDKHRLQQQLNDAENK--Y 794
Q+ LQD +R K E Q +LE ++IKQL QQ+L + +NK Y
Sbjct: 502 HQQISGRLQD-VRLKKQTQKTELEVLDKQCDLEIMEIKQL-------QQELQEYQNKLIY 553
Query: 795 KILEKEF--QQFKDQQ-NNKPEIRLQSEINLLTLEKVELERKL-------ESATKSKLHY 844
+ EK+ ++ K+ Q +N P+ + S ++ +LEK EL ++L E T SKL
Sbjct: 554 LVPEKQLLNERIKNMQFSNTPDSGV-SLLHKKSLEKEELCQRLKEQLDALEKETASKLSE 612
Query: 845 KQQWGRALKELARLKQREQES--QMARLKKQQ-EELEQMRLRYLAAE--EKDTVKTERQE 899
+ LKEL +Q + Q+ ++K+ + +E+E+ RL + + E + + +Q
Sbjct: 613 MDSFNNQLKELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQG 672
Query: 900 LLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEER 952
++ E N +++E+KQ + E K E+ D T EE+
Sbjct: 673 KENLWKE-NLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEK 724
Score = 50.1 bits (118), Expect = 1e-05
Identities = 49/203 (24%), Positives = 92/203 (45%), Gaps = 10/203 (4%)
Query: 626 QQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMWKEMQEDIFENQLK------QKELAH 679
QQ L + Q E L+ + LE+ K++Q+++ E Q K +K+L +
Sbjct: 503 QQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLN 562
Query: 680 MQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKE 739
+ ++ SL+ KK E L +L++ L LEK S + KE
Sbjct: 563 ERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKE 622
Query: 740 LQSERQRNLQELQDSIRRAKEDCIHQVELERLKI---KQLEEDKHRLQQQLNDAENKYKI 796
L+ E Q + + + K D + ++E +RL++ K+LE++ R +Q + K +
Sbjct: 623 LR-ETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENL 681
Query: 797 LEKEFQQFKDQQNNKPEIRLQSE 819
++E ++ K Q K + ++Q E
Sbjct: 682 RKEEEEKQKRLQEEKTQEKIQEE 704
Score = 49.7 bits (117), Expect = 1e-05
Identities = 74/330 (22%), Positives = 150/330 (45%), Gaps = 51/330 (15%)
Query: 589 SNNRIADLSYTVTLEDYGLVKMREIFIS-DSSQGVSAVQQKPSSLPPAPCPSEIQTEPRE 647
S ++A + ++ G +K E ++ + A Q P +LPP P + +
Sbjct: 278 SQTQLATIWTLADVDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQI 337
Query: 648 TLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTI 707
L +++MQE+ E Q K + E+ +K + ER ++ +K
Sbjct: 338 D---SINGTLPSYQKMQEE--EPQKK------LPVTFEDKRKANYERGNMELEK------ 380
Query: 708 LEGKLQKTLIDLEKRE--QQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQ 765
++ L++ ++RE ++ + E +R+++ELQ + + EL+ + + Q
Sbjct: 381 ----RRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEK-------Q 429
Query: 766 VELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTL 825
ELER + ++ +D R + + E + ++ E+++ + Q+ + R Q EI L
Sbjct: 430 RELERQREEERRKDIERREAAKQELERQRRL---EWERIRRQELLNQKNREQEEIVRLNS 486
Query: 826 EKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYL 885
+K L +LE+ L+ K Q + RLK++ Q++++ L KQ +LE M ++ L
Sbjct: 487 KKKNLHLELEA-----LNGKHQQISGRLQDVRLKKQTQKTELEVLDKQC-DLEIMEIKQL 540
Query: 886 AAEEKDTVKTERQELLDIRNELNRLRQQEQ 915
+QEL + +N+L L ++Q
Sbjct: 541 -----------QQELQEYQNKLIYLVPEKQ 559
Score = 42.7 bits (99), Expect = 0.002
Identities = 58/226 (25%), Positives = 104/226 (46%), Gaps = 40/226 (17%)
Query: 724 QQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRL 783
+Q+ S+ L +K + E Q+ L + R+A + +ELE+ + +E
Sbjct: 335 KQIDSINGTLPSYQKMQEEEPQKKLPVTFEDKRKANYER-GNMELEKRRQALME------ 387
Query: 784 QQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLH 843
QQ +AE K + EKE + K ++ + E + Q E+ ++ ELER+ E + +
Sbjct: 388 -QQQREAERKAQ-KEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIE 445
Query: 844 YKQ------------QWGRALK-ELARLKQREQESQMARLKKQQE----ELEQMRLRYLA 886
++ +W R + EL K REQE ++ RL +++ ELE + ++
Sbjct: 446 RREAAKQELERQRRLEWERIRRQELLNQKNREQE-EIVRLNSKKKNLHLELEALNGKHQQ 504
Query: 887 AE--------EKDTVKTERQELLDIRNELNRLR----QQEQKQYQD 920
+K T KTE E+LD + +L + QQE ++YQ+
Sbjct: 505 ISGRLQDVRLKKQTQKTE-LEVLDKQCDLEIMEIKQLQQELQEYQN 549
Score = 34.7 bits (78), Expect = 0.45
Identities = 25/101 (24%), Positives = 50/101 (49%)
Query: 825 LEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRY 884
+++ E ++KL + K + G E R EQ+ + A K Q+E+ E R +
Sbjct: 350 MQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQR 409
Query: 885 LAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIA 925
E++ + E ++ L+ + EL R R++E+++ + E A
Sbjct: 410 ELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAA 450
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 68.9 bits (167), Expect = 2e-11
Identities = 84/314 (26%), Positives = 158/314 (50%), Gaps = 41/314 (13%)
Query: 627 QKPSSLPPAPCPSEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEE 686
Q+P+ P SEI E R +LE E Q+ QL+Q + H++ +
Sbjct: 65 QRPAVSAPVGA-SEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQ-PHLELQQQP 122
Query: 687 WKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQ-QLASVESELQREKKELQSERQ 745
+ ++ L ++K E K + L+ +++ Q Q + LQ+++++LQ+++
Sbjct: 123 QQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQA 182
Query: 746 RNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFK 805
+ Q LQ +E QV+ ++L L++ + +LQQQ ++L+++ +Q +
Sbjct: 183 QEQQVLQQ-----QEQLQQQVQEQQL----LQQQQEQLQQQ--------QLLQQQ-EQLQ 224
Query: 806 DQQNNKPEIRLQSEINLLTLEKV-ELERKLESATKSKLHYK--QQWGRALKELARLKQRE 862
QQ + + +LQ + LL L++ +L+++L +++L + +Q L++ L+Q+E
Sbjct: 225 QQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQE 284
Query: 863 Q--ESQMARLK-KQQEELEQMRLR--YLAAEEKDTVKTE--------RQELLDIRNELNR 909
Q + Q +L +QQE+L+Q +L+ L EE++ V+ E QEL R EL R
Sbjct: 285 QLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELER 344
Query: 910 L----RQQEQKQYQ 919
RQQEQ+Q Q
Sbjct: 345 QQELERQQEQRQLQ 358
Score = 62.0 bits (149), Expect = 3e-09
Identities = 68/315 (21%), Positives = 153/315 (48%), Gaps = 43/315 (13%)
Query: 611 REIFISDSSQGVSAVQQKPSSLPPAPCPS-EIQTEPRETLEYKAALELEMWKEMQEDIFE 669
RE+ + Q QQ P P E+Q +P++ + + + ++ +E + +
Sbjct: 87 RELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLS---QLQQEKHQSVHH 143
Query: 670 NQLKQK-ELAHMQAL-----AEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKRE 723
+LK + +L H Q +E ++ +++E L ++ E +L+ Q+ + + +E
Sbjct: 144 QELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQ---QQEQLQQQVQE 200
Query: 724 QQLASVESELQREKKELQSE---RQRNLQELQDSIRRAKEDCI--HQVELERLKIKQ--- 775
QQL + E ++++ LQ + +Q+ Q+ Q+ +++ ++ + Q +L++ ++Q
Sbjct: 201 QQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQA 260
Query: 776 ------LEEDKHRLQQQL-------NDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINL 822
LE+ + +LQQQL + + ++L+++ +Q + QQ P + + E
Sbjct: 261 QLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEE--- 317
Query: 823 LTLEKVELE-RKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMR 881
E+VELE ++ ++ +L ++Q +EL R Q+EQ +L+++ ++LEQ
Sbjct: 318 ---EEVELELMPVDLGSEQELEQQRQELERQQELER--QQEQRQLQLKLQEELQQLEQQL 372
Query: 882 LRYLAAEEKDTVKTE 896
+ E+ V+ E
Sbjct: 373 EQQQQQLEQQEVQLE 387
Score = 49.3 bits (116), Expect = 2e-05
Identities = 45/236 (19%), Positives = 112/236 (47%), Gaps = 20/236 (8%)
Query: 739 ELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILE 798
E+ E + +ELQ +++ ++ Q + + +++Q + QQ D + + L+
Sbjct: 77 EIAEETRPGQRELQ--LQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQ 134
Query: 799 KEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARL 858
+E Q Q KPE++L + L ++V+ +++L+ + + Q + L++ +L
Sbjct: 135 QEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQL 194
Query: 859 KQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQY 918
+Q+ QE Q+ L++QQE+L+Q +L ++QE L + + +QQ+++
Sbjct: 195 QQQVQEQQL--LQQQQEQLQQQQL------------LQQQEQL----QQQQFQQQQEQLQ 236
Query: 919 QDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQ 974
Q + ++ +L++ +L+E++ ++ + + + + +Q
Sbjct: 237 QQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQ 292
Score = 41.2 bits (95), Expect = 0.005
Identities = 52/249 (20%), Positives = 118/249 (47%), Gaps = 57/249 (22%)
Query: 638 PSEIQTEPR-----ETLEYKAALE---LEMWKEMQEDIFENQL---KQKELAHMQALAEE 686
P ++Q + R E L+ + A E L+ +++Q+ + E QL +Q++L Q L ++
Sbjct: 161 PQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ 220
Query: 687 WKKRDRERESLVKKKVAEYTIL----EGKLQKTLIDLEKR-------EQQLASVESEL-- 733
+ + ++ + ++ + +L +G+LQ+ L+ ++ EQQ A ++ +L
Sbjct: 221 EQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLL 280
Query: 734 QREKKELQSERQRNLQELQDSIRRAK-------------------------EDCIHQV-- 766
Q++++ Q ++Q+ LQ+ Q+ +++ + E + Q
Sbjct: 281 QQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQ 340
Query: 767 ELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLE 826
ELER + + ++++ +LQ +L + L++ QQ + QQ + +Q E+ + L
Sbjct: 341 ELERQQELERQQEQRQLQLKLQEE------LQQLEQQLEQQQQQLEQQEVQLELTPVELG 394
Query: 827 KVELERKLE 835
+ E +LE
Sbjct: 395 AQQQEVQLE 403
Score = 34.3 bits (77), Expect = 0.59
Identities = 33/113 (29%), Positives = 54/113 (47%), Gaps = 6/113 (5%)
Query: 640 EIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVK 699
++Q P E E + +ELE+ E + +++EL Q L +R +E+ L
Sbjct: 306 QLQPPPLEP-EEEEEVELELMPVDLGSEQELEQQRQELERQQEL-----ERQQEQRQLQL 359
Query: 700 KKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQ 752
K E LE +L++ LE++E QL EL +++E+Q E ELQ
Sbjct: 360 KLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQ 412
Score = 33.9 bits (76), Expect = 0.77
Identities = 32/152 (21%), Positives = 77/152 (50%), Gaps = 12/152 (7%)
Query: 650 EYKAALELEMWKEMQEDIFENQ---LKQKELAHMQALAEEWKKRDRERESLVKKKVAEYT 706
+ +A L+ ++ + QE + + Q L Q++ +Q + + E E V+ ++
Sbjct: 269 QQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVD 328
Query: 707 I-LEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQ 765
+ E +L++ +LE+++ E E Q+E+++LQ + Q LQ+L+ + + ++ Q
Sbjct: 329 LGSEQELEQQRQELERQQ------ELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQ 382
Query: 766 -VELERLKIKQLEEDKHRLQQQLNDAENKYKI 796
V+LE + +L + +Q +L + + ++
Sbjct: 383 EVQLELTPV-ELGAQQQEVQLELTPVQPELQL 413
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 68.9 bits (167), Expect = 2e-11
Identities = 71/318 (22%), Positives = 147/318 (46%), Gaps = 37/318 (11%)
Query: 640 EIQTEPRETLEYKAALELE-MWKEMQEDIFENQLKQKELAHMQALAEE--WKKRDRERES 696
E++ + +E E K E E +E +E ++E + K +E EE W++ + RE
Sbjct: 291 ELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ 350
Query: 697 LVKKKVAEYTILEG-----KLQKTLIDLEKR-EQQLASVESELQREKKELQSERQRNLQE 750
K + E + E + ++ + + EK EQ+ E E RE+++ E + ++E
Sbjct: 351 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMRE 410
Query: 751 LQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQN- 809
++ +++ +E+ Q E E + ++L E K +L +Q E + KI E+E ++ +DQ+
Sbjct: 411 QEEKMQKQEENMWEQEEKEWQQ-QRLPEQKEKLWEQEKMQEQEEKIWEQE-EKIRDQEEM 468
Query: 810 --------NKPEIRLQSEINLLTLEKV---------------ELERKLESATKSKLHYKQ 846
+ ++R Q + EK+ E + +L + K+
Sbjct: 469 WGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKK 528
Query: 847 QWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNE 906
W + K K +EQE + +++ E E+MR R E++ + E++E + + E
Sbjct: 529 MWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 588
Query: 907 LNRLRQQEQKQYQDSTEI 924
++R+QE+K ++ ++
Sbjct: 589 --KMREQEEKMWEQEEKM 604
Score = 67.8 bits (164), Expect = 5e-11
Identities = 66/279 (23%), Positives = 139/279 (49%), Gaps = 16/279 (5%)
Query: 647 ETLEYKAALELEMWKEMQEDIFENQLKQK--ELAHMQALAEEWKKRDRERESLVKKKVAE 704
E + + AL LE+++ I +LK+K EL LAE K + +K+K+
Sbjct: 163 ELTKERDALSLELYRNT---ITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLER 219
Query: 705 YTILEGKLQKTLIDLE--KREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDC 762
L ++Q + E ++E++L E +++++++++ + +R L+E + +R +E
Sbjct: 220 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER-LREQEGKMREQEEKM 278
Query: 763 IHQVELERLKIKQLEEDKHRLQQQ--LNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEI 820
Q + R + K+L E + L++Q L + E + + E++ + +++ + E + E
Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
Query: 821 NLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQM 880
L EK E++ + + + ++Q KE + REQE + +K QEE E++
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE---RMREQEKMWEQEEKMQEE-ERI 394
Query: 881 RLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQ 919
R R E++ E++E + + E + +QE+K++Q
Sbjct: 395 REREKKMREEEETMREQEEKMQKQEE--NMWEQEEKEWQ 431
Score = 65.5 bits (158), Expect = 2e-10
Identities = 78/364 (21%), Positives = 165/364 (45%), Gaps = 46/364 (12%)
Query: 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAE------EWKKRDRERE 695
+ E RE + E +MW++ +E + E + K +E E E + R++E+E
Sbjct: 240 EEELREQEKKIRKQEEKMWRQ-EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 696 SLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSI 755
+KK+ E E ++Q+ + ++E+++ E ++ R+++ L E+++ ++E + +
Sbjct: 299 LREQKKLREQ---EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW-EQEKQMREQEQKM 354
Query: 756 RRAKEDCIHQVELERLKIKQL-EEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEI 814
R +E Q E R K +++ E++K Q++ E + + EK+ ++ ++ + E
Sbjct: 355 RDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEK 414
Query: 815 RLQSEINLLTLEKVELERKLESATKSKL---------------------HYKQQWGRALK 853
+ E N+ E+ E +++ K KL ++ WG+ K
Sbjct: 415 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474
Query: 854 ELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQ 913
+ K REQE QM +Q+E++ + EE+ + ER +R + R+R+Q
Sbjct: 475 MWRQEKMREQEDQMW---EQEEKMRDQEQKMWDQEERMWEQDER-----LREKEERMREQ 526
Query: 914 EQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDR 973
+K +Q ++ KK E+ D ++ EE R E+ ++ E +
Sbjct: 527 -KKMWQQEEKMREEKKTQEQ----EKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 581
Query: 974 QIRE 977
+++E
Sbjct: 582 KMQE 585
Score = 65.1 bits (157), Expect = 3e-10
Identities = 62/278 (22%), Positives = 129/278 (46%), Gaps = 20/278 (7%)
Query: 655 LELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQK 714
L+ EMW++ E +L+++E + + W++ +R RE K + E + + +
Sbjct: 232 LQEEMWRQ------EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL 285
Query: 715 TLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIK 774
+ E REQ+ E + RE++E E++ + E ++ +R +E Q E + K
Sbjct: 286 REQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 345
Query: 775 QLEEDKHRLQQQLNDA-ENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKV---EL 830
Q+ E + +++ Q E ++ EKE + + ++ + E ++Q E + EK E
Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE 405
Query: 831 ERKLESATKSKLHYKQQWGRALKELARLKQREQESQM---ARLKKQQEELEQMRLRYLAA 887
E E K + + W + KE + + EQ+ ++ ++++Q+E++ + +
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 888 EEK--DTVKTERQELL-----DIRNELNRLRQQEQKQY 918
EE K RQE + + + ++R QEQK +
Sbjct: 466 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
Score = 62.4 bits (150), Expect = 2e-09
Identities = 60/304 (19%), Positives = 146/304 (48%), Gaps = 23/304 (7%)
Query: 640 EIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVK 699
E + + RE + E MW E E + E + + +E M E+ ++ +R RE K
Sbjct: 342 EQEKQMREQEQKMRDQEERMW-EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400
Query: 700 KKVAEYTILEG--KLQKTLIDL----EKREQQLASVESELQREKKELQSERQRNLQELQD 753
+ E T+ E K+QK ++ EK QQ E + + ++E E++ + E ++
Sbjct: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Query: 754 SIRRAKEDCIHQVELERL-KIKQLEEDKHRLQQQLNDAENKY------------KILEKE 800
IR +E + ++ R K+++ E+ ++++ D E K ++ EKE
Sbjct: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE 520
Query: 801 FQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQ 860
+ + ++ + E +++ E EK +++ + + ++ +++ R +E+ R ++
Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
Query: 861 REQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQD 920
+ + Q ++++Q+E++ + + EEK E++E + + E +++++QE+ ++
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEK---MWEQEEKMWEQEEEDKMQEQEEMMWEQ 637
Query: 921 STEI 924
++
Sbjct: 638 EEKM 641
Score = 60.8 bits (146), Expect = 6e-09
Identities = 53/279 (18%), Positives = 142/279 (50%), Gaps = 25/279 (8%)
Query: 656 ELEMWK-----EMQEDIFENQLKQKELAHMQALAEE--WKKRDRERESLVKKKVAEYTIL 708
E +MW+ E ++ ++E + K ++ EE W++ +R RE ++++ E +
Sbjct: 472 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK--EERMREQKKM 529
Query: 709 EGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVEL 768
+ +K + + +EQ+ + + E + ++E ER++ ++E ++ +R +E Q E
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 769 ERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKV 828
R + +++ E + ++Q+Q + K+ E+E + ++ ++ +K ++ Q E+ EK+
Sbjct: 590 MREQEEKMWEQEEKMQEQ------EEKMWEQEEKMWEQEEEDK--MQEQEEMMWEQEEKM 641
Query: 829 ELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAE 888
+ + + + K+ +++ R +E + ++ + Q +++ Q+E++ + + E
Sbjct: 642 QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE 701
Query: 889 EKDTVKTER----QELL----DIRNELNRLRQQEQKQYQ 919
EK + E+ +E + ++R + R+R Q++K +
Sbjct: 702 EKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQE 740
Score = 60.1 bits (144), Expect = 1e-08
Identities = 61/255 (23%), Positives = 124/255 (48%), Gaps = 21/255 (8%)
Query: 676 ELAHMQALAEEW-KKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQ 734
EL + W KK DR E L K++ A L +L + I E+ +++ A ++ +L+
Sbjct: 142 ELQRALSAVSTWHKKADRYIEELTKERDA----LSLELYRNTITNEELKKKNAELQEKLR 197
Query: 735 REKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKY 794
+ E +SE Q N++EL+ + RAK L +++ L+E+ R +++L + E K
Sbjct: 198 LAESE-KSEIQLNVKELKRKLERAK------FLLPQVQTNTLQEEMWRQEEELREQEKKI 250
Query: 795 KILEKEF----QQFKDQQNN---KPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQ 847
+ E++ ++ ++Q+ + E + E L EK E++ E + KL +++
Sbjct: 251 RKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEE 310
Query: 848 WGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLD--IRN 905
+ +E ++ + Q ++ +Q+E L + + E+K + ER D +R
Sbjct: 311 QMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLRE 370
Query: 906 ELNRLRQQEQKQYQD 920
+ R+R+QE+ Q+
Sbjct: 371 KEERMREQEKMWEQE 385
Score = 57.8 bits (138), Expect = 5e-08
Identities = 61/278 (21%), Positives = 137/278 (49%), Gaps = 11/278 (3%)
Query: 646 RETLEYKAALELEMWKEMQEDIFENQL-KQKELAHMQALAEEWKKRDRERESLVKKKVAE 704
RE E E MW++ +++ + +L +QKE Q +E +++ E+E +K+ +
Sbjct: 409 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE----EKIRD 464
Query: 705 YTILEGKLQKTLIDLEKREQQLASVESELQ-REKKELQSERQRNLQELQDSIRRAKEDCI 763
+ G+ +K + REQ+ E E + R++++ +++ + E + +R +E
Sbjct: 465 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMR 524
Query: 764 HQVELERLKIKQLEEDKHRLQQQLN-DAENKYKILEKEFQQFKDQQNNKPEIRLQSEINL 822
Q ++ + + K EE K + Q++ D E K + E+ ++ K + + +R Q E
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 584
Query: 823 LTLEKV-ELERKL-ESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQM 880
EK+ E E K+ E K + ++ W + K + ++ + + Q + +Q+E++++
Sbjct: 585 EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQ 644
Query: 881 RLRYLAAEEKDTVKTE--RQELLDIRNELNRLRQQEQK 916
+ EEK + E R++ ++ + ++R+QE+K
Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEK 682
Score = 46.6 bits (109), Expect = 1e-04
Identities = 45/247 (18%), Positives = 122/247 (49%), Gaps = 27/247 (10%)
Query: 642 QTEPRETLEYKAALELEMWKE---MQEDIFENQLKQKELAHMQALAEEWKKRDRER---- 694
Q E E + + +MW++ M+E+ + ++K + + EE + R+RE+
Sbjct: 512 QDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571
Query: 695 -ESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESEL-QREKKELQSERQRNLQELQ 752
E +++++ + E K+++ + ++E+++ E ++ ++E+K + E + +QE +
Sbjct: 572 EEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQE 631
Query: 753 DSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKP 812
+ + +E Q E + +++ E + ++++Q E K + E++ ++ +++ +
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ----EEKMQGQEEKMREQEEKMQGQE 687
Query: 813 EIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKK 872
E + E EK+ + + + K+ WG+ K + + RE+E R++
Sbjct: 688 EKMREQE------EKMRGQEEKMWGQEEKM-----WGQEEKMWGQEEMREKEE---RIRD 733
Query: 873 QQEELEQ 879
Q+E++++
Sbjct: 734 QKEKMQE 740
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 68.9 bits (167), Expect = 2e-11
Identities = 90/345 (26%), Positives = 160/345 (46%), Gaps = 47/345 (13%)
Query: 647 ETLEYKAALE--LEMWKEMQEDI--FENQLKQKELAHMQALAEEWKKRDRE---RESLVK 699
E LE K ++ +K+M+ DI +++QL+ K+ + L +E + E SL+
Sbjct: 647 ENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVD-LEKELQSAFNEITKLTSLID 705
Query: 700 KKVAEYTILEGKLQKTLIDLEKR------EQQLASVESELQREKKELQSERQRNLQELQD 753
KV + + +L+ + DL+K E + E L E K L SE +R +E+QD
Sbjct: 706 GKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQD 765
Query: 754 S------IRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKD- 806
I K+ +V + +++ L E+ + + L ++ YK ++EFQ FK
Sbjct: 766 KSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTL 825
Query: 807 ----QQNNKPEI----RLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARL 858
+Q K + R+ EI L+ E + + L A K++L YK Q L+E
Sbjct: 826 HMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSL-GALKTELSYKTQ---ELQE---- 877
Query: 859 KQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQ--K 916
K RE + ++ +++ +E+LE E + T+ TE+ L E+ L Q++ K
Sbjct: 878 KTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEK--LQQTLEEVKTLTQEKDDLK 935
Query: 917 QYQDSTEIASGK-KDGPHGSV-----LEEGLDDYLTRLIEERDTL 955
Q Q+S +I + K H +V +E L + L L + ++T+
Sbjct: 936 QLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETI 980
Score = 65.5 bits (158), Expect = 2e-10
Identities = 77/289 (26%), Positives = 130/289 (44%), Gaps = 33/289 (11%)
Query: 654 ALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQ 713
AL+ E+ + QE + + Q+ L M+ L E+ + RD +++ ++K T++ KLQ
Sbjct: 863 ALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREK----TLITEKLQ 918
Query: 714 KTLIDLEKREQQ---LASVESELQREKKELQSERQRNLQ---ELQDSIRRAKEDCI-HQV 766
+TL +++ Q+ L ++ LQ E+ +L+S+ + + Q+ +R A E HQ
Sbjct: 919 QTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQE 978
Query: 767 ELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQ-------------NNKPE 813
+ LK K EE L + N E K + +K K Q +
Sbjct: 979 TINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEI 1038
Query: 814 IRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMA---RL 870
I Q +I L EK EL++ LES + K+Q LKE + QE L
Sbjct: 1039 IEQQRKIFSLIQEKNELQQMLESV----IAEKEQLKTDLKENIEMTIENQEELRLLGDEL 1094
Query: 871 KKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQ 919
KKQQE + Q + + E + + +R L ++ +L QQ Q++ Q
Sbjct: 1095 KKQQEIVAQEKNHAIKKEGELSRTCDR--LAEVEEKLKEKSQQLQEKQQ 1141
Score = 64.7 bits (156), Expect = 4e-10
Identities = 66/293 (22%), Positives = 143/293 (48%), Gaps = 27/293 (9%)
Query: 643 TEPRETLE-YKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKK- 700
T+ R+ L+ K ALE++ +++E I E K +E Q + K++D E +V +
Sbjct: 1348 TKERDNLKTIKEALEVKH-DQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEM 1406
Query: 701 ---KVAEYTILEGKLQKTLIDLEKREQQ-------LASVESELQREKKELQSERQRNLQE 750
K + +L +++ ++ L KR Q+ +A + +LQR ++ LQSE + +
Sbjct: 1407 EQFKPKDSALL--RIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKEN 1464
Query: 751 LQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNN 810
+++ + + E ++++ +K+ EE + L+ L++ E + ++K+ + D+ N
Sbjct: 1465 IKEIVAKHLET-EEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQN 1523
Query: 811 KPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALK----ELARLKQREQESQ 866
K + + E + E++ K+ + K H K + AL+ ++ L R QESQ
Sbjct: 1524 KIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAK-DSALQSIESKMLELTNRLQESQ 1582
Query: 867 MARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQ 919
+E+ E R++ E+D +K +E+ + ++++ ++K+YQ
Sbjct: 1583 EEIQIMIKEKEEMKRVQEALQIERDQLKENTKEI------VAKMKESQEKEYQ 1629
Score = 56.2 bits (134), Expect = 1e-07
Identities = 65/299 (21%), Positives = 148/299 (49%), Gaps = 43/299 (14%)
Query: 648 TLEYKAALELEMWKE-MQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYT 706
++E +E + KE ++E I + KQ+EL + +E ++ + +V +K E +
Sbjct: 1693 SVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEIS 1752
Query: 707 ILEGKLQKTLIDLEKREQQLASVESELQ------REKKELQSERQRNLQELQDSIRRAKE 760
++ L+ + L+ ++ + ++ EL+ +E++E + + + E D + ++
Sbjct: 1753 NMQKDLEHSNDALKAQDLK---IQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQK 1809
Query: 761 DCIHQVELERLKIKQLEEDKHRL---QQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQ 817
D + + KI++L+ ++H+L ++ +N+ + K +E+ +Q KDQ
Sbjct: 1810 DLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQS--------- 1860
Query: 818 SEINLLTLEKVELE-----RKL-ESATKSKLHYKQQWG-RALKELARLKQREQESQMARL 870
LTL K+E+E +KL E+ + K K++ R ++E +L++ + + +
Sbjct: 1861 -----LTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQET 1915
Query: 871 KKQQEELEQ--MRLRYLAAEEKDTVKTERQ-------ELLDIRNELNRLRQQEQKQYQD 920
K + E++Q R L+ E K+TV R+ ++ DI+ +L++ + + QK+ Q+
Sbjct: 1916 KARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQE 1974
Score = 53.5 bits (127), Expect = 9e-07
Identities = 52/236 (22%), Positives = 114/236 (48%), Gaps = 18/236 (7%)
Query: 711 KLQKTLIDLEKREQQ----LASVESELQREKKELQSERQRNLQELQDSIRRAKEDC---- 762
++ + +++L K Q+ L ++++EL + +ELQ E+ R +QE + + + KE
Sbjct: 842 RMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQ-EKTREVQERLNEMEQLKEQLENRD 900
Query: 763 --IHQVELERL----KIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRL 816
+ VE E+ K++Q E+ L Q+ +D + + L+ E Q K ++ + +
Sbjct: 901 STLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNI 960
Query: 817 QSEINLLT-LEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQE 875
++ L LE ++ ++ + KSK+ + ++E + E + +M + K+Q
Sbjct: 961 DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQ- 1019
Query: 876 ELEQMRLRYLAAEEKDTVKTERQ-ELLDIRNELNRLRQQEQKQYQDSTEIASGKKD 930
+LE + L A+ KD E+Q ++ + E N L+Q + + ++ + K+
Sbjct: 1020 DLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKE 1075
Score = 52.4 bits (124), Expect = 2e-06
Identities = 87/393 (22%), Positives = 173/393 (44%), Gaps = 81/393 (20%)
Query: 649 LEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTIL 708
++ K LE + + + D+ +N++ +++ + +L +E + + ES++ +K T L
Sbjct: 1015 IDKKQDLEAKNTQTLTADVKDNEIIEQQ-RKIFSLIQEKNELQQMLESVIAEKEQLKTDL 1073
Query: 709 EGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVEL 768
+ ++ T+ + +++L + EL+++++ + E+ +++ + R C E+
Sbjct: 1074 KENIEMTI----ENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRT----CDRLAEV 1125
Query: 769 ERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKV 828
E K+K+ + QQQL + + + ++K+ + +N K E++ + LTLE +
Sbjct: 1126 EE-KLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEI---ENLKNELKNKE----LTLEHM 1177
Query: 829 ELERKLESATKSKLHYKQ-----QWGRALKEL-------------------ARLKQREQE 864
E ER LE A K +Y++ + + LKEL A Q ++E
Sbjct: 1178 ETER-LELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEE 1236
Query: 865 SQMA--RLKKQQEELEQMR-----------------LRYLAAEEKDTVKTERQELL---- 901
++A LK+ QE ++++R + +E+ V E QELL
Sbjct: 1237 LKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVK 1296
Query: 902 ------DIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERD-- 953
+ NEL L EQ +DST +A + + + + + + L +ERD
Sbjct: 1297 EVSETQETMNELELL--TEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNL 1354
Query: 954 -TLMRTGVYNHEDRIISELDRQIREILAKSNAS 985
T+ H+ +L IRE LAK S
Sbjct: 1355 KTIKEALEVKHD-----QLKEHIRETLAKIQES 1382
Score = 50.1 bits (118), Expect = 1e-05
Identities = 74/340 (21%), Positives = 158/340 (46%), Gaps = 43/340 (12%)
Query: 609 KMREIFISDSS---QGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEMWKEMQE 665
K++EI+ + + +S VQ+K + L + + +++E K LE+ +QE
Sbjct: 1524 KIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKM---LELTNRLQE 1580
Query: 666 DIFENQLKQKELAHMQALAEEWK-KRDRERES-------LVKKKVAEYTILE----GKLQ 713
E Q+ KE M+ + E + +RD+ +E+ + + + EY L+ + Q
Sbjct: 1581 SQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQ 1640
Query: 714 KTLIDLEKREQQLASVESELQR---EKKELQSERQRNLQELQDSIRRAKEDCIHQVELER 770
+ + ++E ++Q + + L+ E L NL+E++ S+ + ++D + VE E
Sbjct: 1641 EKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMR-SVTKERDD-LRSVE-ET 1697
Query: 771 LKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVEL 830
LK+++ ++ K L++ + K + L+ K+ Q ++R ++ T E +
Sbjct: 1698 LKVER-DQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLR--GIVSEKTNEISNM 1754
Query: 831 ERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEK 890
++ LE + ALK Q E LK+QQE ++ +LR + +E+
Sbjct: 1755 QKDLEHSND-----------ALKAQDLKIQEELRIAHMHLKEQQETID--KLRGIVSEKT 1801
Query: 891 DTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKD 930
D + ++ D+ N +L+++ Q+ + ++ + KKD
Sbjct: 1802 DKLSNMQK---DLENSNAKLQEKIQELKANEHQLITLKKD 1838
Score = 50.1 bits (118), Expect = 1e-05
Identities = 52/260 (20%), Positives = 120/260 (46%), Gaps = 29/260 (11%)
Query: 649 LEYKAALELEMWKEMQEDIFENQLK-QKELAHMQALAEEWKKRDRERESLVKKKVAEYTI 707
+E LE + KE ++ L+ Q+EL + L++E K+ + + +K + +
Sbjct: 1897 VEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISD 1956
Query: 708 LEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVE 767
++ L K+ +L+K+ Q+L E +L R K+++ ++ + E+ E Q E
Sbjct: 1957 IQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKK-INEM--------EQLKKQFE 2007
Query: 768 LERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEK 827
+ L ++ + D +L ++L+++ + +I+ KE + + R++ E
Sbjct: 2008 AQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELR---------RIK--------ES 2050
Query: 828 VELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAA 887
+++ER AT ++ + + +K RL Q+ L+++ ++++ RY +
Sbjct: 2051 LKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRY--S 2108
Query: 888 EEKDTVKTERQELLDIRNEL 907
E D + + LD+ E+
Sbjct: 2109 EMDDHYECLNRLSLDLEKEI 2128
Score = 45.4 bits (106), Expect = 3e-04
Identities = 59/266 (22%), Positives = 119/266 (44%), Gaps = 30/266 (11%)
Query: 683 LAEEW----KKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKK 738
+++EW K + E L K T L Q + + + S ++L EK
Sbjct: 2324 ISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEK- 2382
Query: 739 ELQSERQRNLQELQDSIRRAKEDCIHQVELERLKI-KQLEEDKHRLQQQLNDAENKYKIL 797
++EL++S+ AKE +H+ E + +K+ K+LE + + K L
Sbjct: 2383 ---------IRELENSLHEAKESAMHK-ESKIIKMQKELEVTNDIIAKLQAKVHESNKCL 2432
Query: 798 EKEFQQFKDQQNN--------KPEIR-LQSEINLLTLEKVELERKLE---SATKSKLHYK 845
EK + + Q+ K EI L+ ++ + LEK++ ++ E SATK+ + Y+
Sbjct: 2433 EKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQ 2492
Query: 846 QQWGRALKE-LARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDT-VKTERQELLDI 903
++ R L+E L R +Q + S ++ Q + + + ++T + E + +
Sbjct: 2493 KEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRL 2552
Query: 904 RNELNRLRQQEQKQYQDSTEIASGKK 929
E+++L+QQ ++ + E+ S +
Sbjct: 2553 EKEISKLKQQNEQLIKQKNELLSNNQ 2578
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 68.6 bits (166), Expect = 3e-11
Identities = 62/293 (21%), Positives = 145/293 (49%), Gaps = 11/293 (3%)
Query: 640 EIQTEPRETLEYKAALELEMWKEMQEDIFENQL---KQKELAHMQALAEEWKKRDRERES 696
E + + RE E E MW++ ++ + ++ K++++ + + E +++ R +E
Sbjct: 325 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE 384
Query: 697 LVKKKVAEYTILEGKL--QKTLIDLEKREQQLASVESELQREKKELQSERQRN-LQELQD 753
++ +K + LE K+ Q+ + + E++ Q+ + + +R+++E + RQ ++E ++
Sbjct: 385 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 444
Query: 754 SIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPE 813
IR ++ Q E + K EE+K + Q+++ E K E+ ++Q + + +
Sbjct: 445 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK 504
Query: 814 IRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELAR--LKQREQESQMARLK 871
IR Q E EK+ + + + K+ +++ R +E+ R K EQE K
Sbjct: 505 IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEK 564
Query: 872 KQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
+Q++E + R E+++ V + ++ IR + + ++QE+K ++ +I
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKVWRQEEK---IREQEEKRQEQEEKMWKQEEKI 614
Score = 67.0 bits (162), Expect = 8e-11
Identities = 63/284 (22%), Positives = 142/284 (50%), Gaps = 21/284 (7%)
Query: 650 EYKAALELEMWKEMQEDIFENQ--LKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTI 707
E K + EMW++ +E I E + +QKE H Q EE ++ E+ ++K+ E
Sbjct: 469 EEKRQEQEEMWRQ-EEKIHEQEEIWRQKEKMHEQ---EEKIRKQEEKVWRQEEKIREQ-- 522
Query: 708 LEGKLQKTLIDLEKREQQLASVESELQREKKELQSER---QRNLQELQDSIRRAKEDCIH 764
E K+++ + ++E+++ E + E+K + E+ + QE +D + R +E
Sbjct: 523 -EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE 581
Query: 765 QVEL---ERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPE-IRLQSEI 820
Q E + KI++ EE + ++++ E K + E++ Q+ +++ + E IR Q E+
Sbjct: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641
Query: 821 NLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQM 880
EK+ + + + K+ +++ +E R ++++ Q ++++Q+E +++
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ 701
Query: 881 RLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
+ EEK E++E + + E ++R+QE+K ++ +
Sbjct: 702 EEKMWEQEEK---MCEQEEKMQEQEE--KMRRQEEKMWEQEVRL 740
Score = 65.9 bits (159), Expect = 2e-10
Identities = 66/266 (24%), Positives = 137/266 (51%), Gaps = 20/266 (7%)
Query: 668 FENQLKQKELAHMQALAEEWKKRDRERESLVKKKVA------EYTILEGKLQKTLIDLEK 721
F +L+Q + A+A + KK DR E L K++ A TI + +L++ L++
Sbjct: 173 FAGELEQA----LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE 228
Query: 722 REQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIK---QLEE 778
+ Q + S +SE+Q KEL+ + +R L +A+ D + + EL+ + K Q+EE
Sbjct: 229 KLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK-ELQSVSAKLQAQVEE 287
Query: 779 DK--HRLQQQLNDAENKYKILEKEFQQFKDQ-QNNKPEIRLQSEINLLTLEKVELERKLE 835
++ +RL QQ E K E++ Q+++++ Q + +IR Q E EK+ + ++
Sbjct: 288 NELWNRLNQQ---QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMM 344
Query: 836 SATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKT 895
+ K+ +++ +E R ++ + ++++Q+E + + + EEK +
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 896 ERQELLDIRNELNRLRQQEQKQYQDS 921
+ +E + R E ++R+QE++Q Q++
Sbjct: 405 KIREQEEKRQEEEKIREQEKRQEQEA 430
Score = 62.0 bits (149), Expect = 3e-09
Identities = 71/330 (21%), Positives = 157/330 (47%), Gaps = 46/330 (13%)
Query: 656 ELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKT 715
ELE QE I E + K++E + E +KR +E+E+ + ++ + E K+++
Sbjct: 395 ELEEKMHEQEKIREQEEKRQE----EEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQ 449
Query: 716 LIDLEKREQQLASVESELQREKKELQSERQRNLQEL--QDSIRRAKEDCIHQVELERLKI 773
+ ++E+++ E + EK++ Q E R +++ Q+ I R KE Q E KI
Sbjct: 450 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE----KI 505
Query: 774 KQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKV-ELER 832
++ EE R ++++ + E K + E++ + +++ + E+ + E + EK+ E E+
Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE-KMHEQEKIWEEEK 564
Query: 833 KLESATK-----SKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAA 887
+ E K K+ +++ +E R ++ +++ Q ++ KQ+E++ + +
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQ 624
Query: 888 EEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTR 947
EEK IR + ++R+QE+ + ++ EE + + +
Sbjct: 625 EEK------------IREQEEKIREQEEMTQEQEEKMGE----------QEEKMCEQEEK 662
Query: 948 LIEERDTLMRTGVYNHEDRIISELDRQIRE 977
+ E+ +T+ R ++ I E +++IRE
Sbjct: 663 MQEQEETMWR------QEEKIREQEKKIRE 686
Score = 62.0 bits (149), Expect = 3e-09
Identities = 54/292 (18%), Positives = 151/292 (51%), Gaps = 23/292 (7%)
Query: 650 EYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILE 709
E + E E ++ +E I E + +Q++ A M W++ ++ RE ++K+ E
Sbjct: 402 EQEKIREQEEKRQEEEKIREQEKRQEQEAKM------WRQEEKIREQ--EEKIREQEKKM 453
Query: 710 GKLQKTLIDLEK-REQQLASVESELQREKKELQSERQ-----RNLQELQDSIRRAKEDCI 763
+ ++ + + EK RE++ + E+ R+++++ + + + E ++ IR+ +E
Sbjct: 454 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513
Query: 764 HQVEL---ERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQ---FKDQQNNKPEIRLQ 817
Q E + KI++ EE R ++++ + E ++ EK +Q +++++ + E ++
Sbjct: 514 RQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMW 573
Query: 818 SEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEEL 877
+ + ++ ++ R+ E + + ++Q + K+ +++++E++ Q K +++E
Sbjct: 574 RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE- 632
Query: 878 EQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKK 929
E++R + +E++ E++E + + E ++++QE+ ++ +I +K
Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEE--KMQEQEETMWRQEEKIREQEK 682
Score = 60.1 bits (144), Expect = 1e-08
Identities = 54/294 (18%), Positives = 133/294 (45%), Gaps = 26/294 (8%)
Query: 656 ELEMWKEMQEDIFENQLKQKE-LAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQK 714
E E+W + + E +Q+E + + +E +++ RE+E ++++ + E + +
Sbjct: 287 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE 346
Query: 715 TLIDLEKREQQLASVESELQR------EKKELQSERQRNLQELQDSIRRAKEDCIHQVEL 768
+ ++E+ + E +++R EK+E ++ + E ++ IR +E Q ++
Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 406
Query: 769 ERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKV 828
+ K+ EE+K R Q++ + E K E++ ++ +++ + + + E + EK+
Sbjct: 407 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 466
Query: 829 ELERKLESAT------------------KSKLHYKQQWGRALKELARLKQREQESQMARL 870
E K + K K+H +++ R +E ++ + Q ++
Sbjct: 467 REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI 526
Query: 871 KKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
++Q+E++ + + EE + + E I E R ++QE K ++ +I
Sbjct: 527 REQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR-QEQEDKMWRQEEKI 579
Score = 59.7 bits (143), Expect = 1e-08
Identities = 65/287 (22%), Positives = 137/287 (47%), Gaps = 16/287 (5%)
Query: 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKK 701
Q E E K + E + +E ++E + K + M EE +R E ++K
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378
Query: 702 VAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKED 761
+ + + ++ + +LE++ + + + ++ ++E + Q QE + + R +E
Sbjct: 379 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 438
Query: 762 CIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQ-NNKPEIRLQSEI 820
Q E KI++ E+ R ++++++ E KI E+E +Q +++ + +I Q EI
Sbjct: 439 IREQEE----KIREQEKKMWRQEEKIHEQE---KIREEEKRQEQEEMWRQEEKIHEQEEI 491
Query: 821 NLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQM 880
+ E E K+ + K+ +++ R +E K REQE +M R +++ E E+M
Sbjct: 492 WRQKEKMHEQEEKIRK-QEEKVWRQEEKIREQEE----KIREQEEKMWRQEEKIREQEEM 546
Query: 881 --RLRYLAAEEKDTVKTERQELLD-IRNELNRLRQQEQKQYQDSTEI 924
+ +EK + +RQE D + + ++R+QE+K ++ +I
Sbjct: 547 WREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKI 593
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/162 (21%), Positives = 83/162 (51%), Gaps = 8/162 (4%)
Query: 642 QTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKK 701
Q E R+ E K + E +E +E I E + K +E EE + E+ ++K
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 702 VAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKED 761
+ E E K+Q+ + ++E+++ E +++ ++++++ E++ +QE ++ + +E
Sbjct: 656 MCEQ---EEKMQEQEETMWRQEEKIREQEKKIREQEEKIR-EQEEMMQEQEEKMWEQEEK 711
Query: 762 CIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQ 803
Q E K+++ EE R ++++ + E + + E++ Q+
Sbjct: 712 MCEQEE----KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 68.6 bits (166), Expect = 3e-11
Identities = 69/278 (24%), Positives = 147/278 (52%), Gaps = 28/278 (10%)
Query: 661 KEMQE--DIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLID 718
+++QE DI+E +L Q + + A AEE K ++ ++ V + L+ +L + D
Sbjct: 1790 EDLQEKCDIWEKKLAQTK--RVLAAAEENSKMEQSNLEKLELNVRK---LQQELDQLNRD 1844
Query: 719 LEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEE 778
+++++ +LQ EK+E + Q L +QD + AK+D +H + + + L
Sbjct: 1845 KLSLHNDISAMQQQLQ-EKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDV----LLS 1899
Query: 779 DKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESAT 838
++ RLQ+ +++ N+++ +KE ++ K QQ LQ+EI L+ V+ E +
Sbjct: 1900 EQTRLQKDISEWANRFEDCQKE-EETKQQQLQV----LQNEIEENKLKLVQQEMMFQ--- 1951
Query: 839 KSKLHYKQQWGRALKELARLKQREQESQMAR-LKKQQEELEQMRLRYLAAEEK-DTVKTE 896
+L +++ + E +++ +EQ+ Q+ + L Q+ +L+Q+ + LAAEE+ T++ E
Sbjct: 1952 --RLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEE 2009
Query: 897 RQELLDIRNELNRLRQQ----EQKQYQDSTEIASGKKD 930
+ + L++ ++Q EQ+ + S E+ + +K+
Sbjct: 2010 ERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKE 2047
Score = 61.6 bits (148), Expect = 3e-09
Identities = 80/347 (23%), Positives = 164/347 (47%), Gaps = 57/347 (16%)
Query: 658 EMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLI 717
E +++Q+DI ++ E H+Q L +E E L++ K AE L+K
Sbjct: 1545 EELQKLQKDI--EMAERNEDHHLQVL--------KESEVLLQAKRAE-------LEKLKS 1587
Query: 718 DLEKREQQLASVESELQREKKE---LQSERQRNLQELQDSIR----RAKEDCIHQVELER 770
+ ++Q++A ++ +L +K+E LQ + +LQ+++R E C H E++
Sbjct: 1588 QVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKS 1647
Query: 771 LKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKD------QQNNKPEIRLQSEINLLT 824
L +++L K L Q+++ + + ++++E ++ ++ +Q +K + L++ +++L
Sbjct: 1648 L-LEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQ 1706
Query: 825 LEKVELE----------RKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQ 874
LE EL+ +LE + L K + L+++++ ++ E E Q L++ +
Sbjct: 1707 LENHELQGLKLQHDQRVSELEKTQVAVLEEKLEL-ENLQQISQQQKGEIEWQKQLLERDK 1765
Query: 875 EELEQM----RLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKD 930
E+E+M R E K + QE DI E+K Q +A+ +++
Sbjct: 1766 REIERMTAESRALQSCVECLSKEKEDLQEKCDI---------WEKKLAQTKRVLAAAEEN 1816
Query: 931 GPHGSVLEEGLDDYLTRLIEERDTLMRTGVYNHEDRIISELDRQIRE 977
E L+ + +L +E D L R + H D IS + +Q++E
Sbjct: 1817 SKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHND--ISAMQQQLQE 1861
Score = 53.5 bits (127), Expect = 9e-07
Identities = 75/338 (22%), Positives = 138/338 (40%), Gaps = 23/338 (6%)
Query: 612 EIFISDSSQGVSAVQQKPSSLPP-------APCPSEIQTEPRETLEYKAALELEMWKEMQ 664
E +I DS+Q V + +P P + Q E +E A L +
Sbjct: 401 ESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEI 460
Query: 665 EDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQ 724
E + L+ E A + KK + L+ K+++ L KL++ +DL E
Sbjct: 461 EKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDL---EL 517
Query: 725 QLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQ 784
Q+ + E+ ++KE+ ++LQ DS+ H + K +QL+ + Q
Sbjct: 518 QMEKQKQEIAGKQKEI-----KDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQ 572
Query: 785 QQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHY 844
Q + + + KE ++ KD + E ++ + L K +LE + +
Sbjct: 573 QLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEAL----KKDLEGVISGLQEYLGTI 628
Query: 845 KQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIR 904
K Q +A E +L+ E+E+ + RL + ++E +Q+ + + AE E + L +
Sbjct: 629 KGQATQAQNECRKLRD-EKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQ 687
Query: 905 NELNRLRQQEQ---KQYQDSTEIASGKKDGPHGSVLEE 939
+E+N QQ Q Y+ E +D + EE
Sbjct: 688 HEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEE 725
Score = 50.4 bits (119), Expect = 8e-06
Identities = 82/334 (24%), Positives = 141/334 (42%), Gaps = 46/334 (13%)
Query: 646 RETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEY 705
RE+ E K KE Q + E +L ++ Q L++ +R R +++ E
Sbjct: 1957 RESEESKLETSKVTLKEQQHQL-EKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCES 2015
Query: 706 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQ 765
LE L +T L +REQQL EL +KE S R + L++ ++ Q
Sbjct: 2016 --LEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMR-ADFSLLRNQFLTERKKAEKQ 2072
Query: 766 VE--LERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLL 823
V E LKI++ + +K+ L+Q+ EN E + Q N++ RL E+N +
Sbjct: 2073 VASLKEALKIQRSQLEKNLLEQK---QENSCIQKEMATIELVAQDNHERARRLMKELNQM 2129
Query: 824 TLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLR 883
E EL+ K++A K L+++Q E+ +R
Sbjct: 2130 QYEYTELK---------------------KQMANQKD---------LERRQMEISD-AMR 2158
Query: 884 YLAAEEKDTVKTERQELLDIRNELNR-LRQQEQKQYQDSTEIASGKKDGP---HGSVLEE 939
L +E KD ++T + L EL L ++ E+ S K++ P + EE
Sbjct: 2159 TLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEE 2218
Query: 940 GLDDYLTRLIEE--RDTLMRTGVYNHEDRIISEL 971
L+ +++E R +R + + EDR+ ++L
Sbjct: 2219 KLNFSQVHIMDEHWRGEALREKLRHREDRLKAQL 2252
Score = 50.1 bits (118), Expect = 1e-05
Identities = 59/272 (21%), Positives = 132/272 (48%), Gaps = 21/272 (7%)
Query: 665 EDIFEN-QLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKRE 723
EDI ++ + K++E M+A + +K E + + E LE ++++ ++KR+
Sbjct: 1329 EDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQ 1388
Query: 724 QQLASVESELQREKKELQSERQ-RNLQELQDSIRRAKEDCIHQVELE-RLKIKQLEEDKH 781
QQ ++ ++ EL+ E+ ++ +++ D I +CI + L+ R ++++ +
Sbjct: 1389 QQKDFIDGNVESLMTELEIEKSLKHHEDIVDEI-----ECIEKTLLKRRSELREADRLLA 1443
Query: 782 RLQQQLNDAENKYKILEKEFQQFK----DQQNNKPEIRLQSEINLLTLEKVELE-RKLES 836
+ +L+ + K K ++F K +++ E+ +++ + L K + + R L++
Sbjct: 1444 EAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQA 1503
Query: 837 ATKSKLHYKQQWGRALKELARL-KQREQESQMARLKKQQ--EELEQMRLRYLAAEEKD-- 891
K +K + LKE+ ++ ++ + Q KK++ EEL++++ AE +
Sbjct: 1504 DAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDH 1563
Query: 892 --TVKTERQELLDI-RNELNRLRQQEQKQYQD 920
V E + LL R EL +L+ Q Q Q+
Sbjct: 1564 HLQVLKESEVLLQAKRAELEKLKSQVTSQQQE 1595
Score = 44.3 bits (103), Expect = 6e-04
Identities = 63/317 (19%), Positives = 130/317 (41%), Gaps = 36/317 (11%)
Query: 639 SEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLV 698
+E++ E R+ LE A M KE+ E Q + + A +Q + + E E+ +
Sbjct: 654 TEVEQE-RDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARL 712
Query: 699 KKKVAEYTILEGKLQKTL-----------IDLEKREQQLASV--ESELQREKKELQSERQ 745
+ AE L+ +L+K +LEK Q L + +++ EK++ SE
Sbjct: 713 NLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELH 772
Query: 746 RNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFK 805
L+ LQD K+ QL++ ++ L ++ ++ + + +
Sbjct: 773 AKLKHLQDDNNLLKQ--------------QLKDFQNHLNHVVDGLVRPEEVAARVDELRR 818
Query: 806 DQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLK-QREQE 864
+ E+ + S ++L +L+++ S++ + +W R ++ K Q E
Sbjct: 819 KLKLGTGEMNIHSPSDVLGKSLADLQKQF-----SEILARSKWERDEAQVRERKLQEEMA 873
Query: 865 SQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQ--QEQKQYQDST 922
Q +L QEE Q R L A + + + NE++ L++ + ++ Q T
Sbjct: 874 LQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLT 933
Query: 923 EIASGKKDGPHGSVLEE 939
++ + D +L +
Sbjct: 934 DLQLQEADEEKERILAQ 950
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 67.0 bits (162), Expect = 8e-11
Identities = 53/278 (19%), Positives = 139/278 (50%), Gaps = 23/278 (8%)
Query: 669 ENQLKQKE--LAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQL 726
E Q++++E + + E + + RE+E V+++ + EG++ + + ++E+Q+
Sbjct: 156 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQM 215
Query: 727 ASVESEL------QREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDK 780
E ++ R+++E E++ +Q+ ++ +++ +E Q E R + +Q+ E +
Sbjct: 216 QKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQE 275
Query: 781 HRL---------QQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELE 831
++ ++Q + E + + E++ ++ ++Q + E + E + E+ E
Sbjct: 276 EQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE 335
Query: 832 RKLESATKSKLHYKQQWGRALKELARLKQREQ-ESQMARLKKQQEEL----EQMRLR-YL 885
+K + + + +KQ+ +E KQ EQ Q +++KQ+E++ EQMR +
Sbjct: 336 QKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQ 395
Query: 886 AAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTE 923
E+K+ + +++++ + ++ ++Q +KQ + E
Sbjct: 396 MGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
Score = 66.6 bits (161), Expect = 1e-10
Identities = 50/254 (19%), Positives = 131/254 (51%), Gaps = 15/254 (5%)
Query: 669 ENQLKQKE--LAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQL 726
E Q++++E + + E + + RE+E V+++ + EG++++ + ++E Q+
Sbjct: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 187
Query: 727 ASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQ 786
E ++ ++ ++ E++ + E ++ +++ +E Q E R + +Q+ E + ++Q+Q
Sbjct: 188 REQEGQMGEQEGQM-GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
Query: 787 LNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQ 846
+ + + + K+ +Q ++Q+ ++R Q E L E+ E E + + ++
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEE---QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEE 303
Query: 847 QWGRALKELARLKQ--REQESQMARLKKQQ-EELEQMRLRYLAAEEKDTVKTERQELLDI 903
Q +++ ++ REQE QM + ++Q E+ EQM E+K+ + + +++ +
Sbjct: 304 QMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM------WEQKEQMWKQEEQMGEQ 357
Query: 904 RNELNRLRQQEQKQ 917
++ + +Q +KQ
Sbjct: 358 EEQMQKQEEQVRKQ 371
Score = 65.5 bits (158), Expect = 2e-10
Identities = 48/229 (20%), Positives = 118/229 (51%), Gaps = 9/229 (3%)
Query: 658 EMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLI 717
E ++M E + Q +++++ + + +++ E+E V+K+ + E +++K
Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE 262
Query: 718 DLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLE 777
+ ++E+Q+ E ++ ++K++ + E Q QE + +R +E Q E R + +Q+
Sbjct: 263 QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQE--EQMREQEEQMREQEEQMREQEEQMR 320
Query: 778 EDKHRLQQQLNDA-ENKYKILEKEFQQFK-DQQNNKPEIRLQSEINLLTLEKVELERKLE 835
E + ++ +Q E K ++ E++ Q +K ++Q + E ++Q + + ++ ++ ++ E
Sbjct: 321 EQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEE 380
Query: 836 SATKSKLHYK---QQWGRALKELARLKQ--REQESQMARLKKQQEELEQ 879
K + + +Q G +++ K+ REQE QM K+Q + E+
Sbjct: 381 QMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Score = 65.1 bits (157), Expect = 3e-10
Identities = 49/271 (18%), Positives = 141/271 (52%), Gaps = 21/271 (7%)
Query: 669 ENQLKQKE--LAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQL 726
E Q++++E + + E + + RE+E V+++ + EG++ + + ++E+Q+
Sbjct: 149 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQM 208
Query: 727 ASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQ 786
E ++Q++++++ E++ +++ ++ + +E QV+ + ++++ EE + ++Q
Sbjct: 209 GEQEEQMQKQEEQM-GEQEEQMRKQEEQMGEQEE----QVQKQEEQVQKQEEQMRKQEEQ 263
Query: 787 LNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVEL---ERKLESATKSKLH 843
+ + E + + E+E Q K ++ + E + + + ++ ++ E ++ +
Sbjct: 264 MREQEEQMR--EQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Query: 844 YKQQWGRALKELARLKQR--EQESQMARLKKQ---QEELEQMRLRYLAAEEKDTVKTERQ 898
++Q G+ +++ K++ EQ+ QM + ++Q QEE Q + + +E+ K E Q
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQ 381
Query: 899 ELLDIRNELNRLRQQEQKQYQDSTEIASGKK 929
+R + ++R+QE++ + ++ K+
Sbjct: 382 ----MRKQEEQMRKQEEQMGEQKEQMGEQKE 408
Score = 61.6 bits (148), Expect = 3e-09
Identities = 47/260 (18%), Positives = 131/260 (50%), Gaps = 16/260 (6%)
Query: 669 ENQLKQKE--LAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDLEKREQQL 726
E Q++++E + + E + + RE+E V+++ + EG++++ + ++E Q+
Sbjct: 142 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQM 201
Query: 727 ASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEEDKHRLQQQ 786
E ++ +++++Q + ++ + E ++ +R+ +E Q E ++++ EE + ++Q
Sbjct: 202 GEQEEQMGEQEEQMQKQEEQ-MGEQEEQMRKQEEQMGEQEE----QVQKQEEQVQKQEEQ 256
Query: 787 LNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQ 846
+ E + + E++ ++ ++Q + E Q+E T E+ E R+ E + + +
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKE---QTEQEEQTGEQEEQMREQEEQMREQEEQMR 313
Query: 847 QWGRALKELARLKQREQESQMARLKKQQEELEQM--RLRYLAAEEKDTVKTERQELLDIR 904
+ ++E +++E + ++ E+ EQM + + +E+ K E Q +R
Sbjct: 314 EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQ----VR 369
Query: 905 NELNRLRQQEQKQYQDSTEI 924
+ ++R+QE++ + ++
Sbjct: 370 KQEEQMRKQEEQMRKQEEQM 389
Score = 55.1 bits (131), Expect = 3e-07
Identities = 59/314 (18%), Positives = 152/314 (48%), Gaps = 26/314 (8%)
Query: 639 SEIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKE--LAHMQALAEEWKKRDRERES 696
SEIQ +E ++ + +E Q E Q++++E + + E + + RE+E
Sbjct: 28 SEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 87
Query: 697 LVKKKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIR 756
V+++ + EG++++ + ++E Q+ E +++ ++ +++ E++ ++E + +R
Sbjct: 88 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR-EQEGQVREQEGQVR 146
Query: 757 RAKEDCIHQVELERLKIKQLEEDKHRLQQQLNDA-ENKYKILEKEFQQFK--------DQ 807
+ Q R + Q+ E + ++++Q E + ++ E+E Q + ++
Sbjct: 147 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEE 206
Query: 808 QNNKPEIRLQSEINLLTLEKVELERKLESATKSKLHYKQQWGRALKELARL-KQ------ 860
Q + E ++Q + + ++ ++ ++ E + + ++Q + K+ ++ KQ
Sbjct: 207 QMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMRE 266
Query: 861 -----REQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQ 915
REQE QM + K+Q E+ EQ + E++ E++E +R + ++R+QE+
Sbjct: 267 QEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEE--QMREQEEQMREQEE 324
Query: 916 KQYQDSTEIASGKK 929
+ + ++ K+
Sbjct: 325 QMGKQEEQMWEQKE 338
Score = 52.4 bits (124), Expect = 2e-06
Identities = 35/183 (19%), Positives = 90/183 (49%), Gaps = 9/183 (4%)
Query: 640 EIQTEPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVK 699
E Q + +E K ++ +E + E LKQKE + E +++ RE+E ++
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 700 KKVAEYTILEGKLQKTLIDLEKREQQLASVESELQREKKEL------QSERQRNLQELQD 753
++ + E ++++ + K+E+Q+ + ++ +K+++ E++ +Q+ ++
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366
Query: 754 SIRRAKEDCIHQVELERLKIKQL---EEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNN 810
+R+ +E Q E R + +Q+ EE ++Q+ + + + + E++ + K+Q
Sbjct: 367 QVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRK 426
Query: 811 KPE 813
+ E
Sbjct: 427 QEE 429
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 67.0 bits (162), Expect = 8e-11
Identities = 60/282 (21%), Positives = 140/282 (49%), Gaps = 21/282 (7%)
Query: 651 YKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEG 710
Y LE E ++ +E++ + + K+K + M+ + K + V+ + E I++
Sbjct: 592 YNPGLEFE--RQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQL 649
Query: 711 KLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELER 770
+++K L++R + + +L EK++ + ER R QE++ +R +E+ +V+ E
Sbjct: 650 QIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEEL 709
Query: 771 LKIKQLEEDK--------HRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINL 822
++K+L ++ L Q + + +Y LE E ++ ++Q+ K ++ L + +
Sbjct: 710 QRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQE--KEQVMLVAHLEE 767
Query: 823 LTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRL 882
EK E+ ++ + ++ + ++ R L+ + R +E++ A + EELE+ +L
Sbjct: 768 QLREKQEM---IQLLRRGEVQWVEEEKRDLEGIRESLLRVKEAR-AGGDEDGEELEKAQL 823
Query: 883 RYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEI 924
R+ + + VK L+++ +L + + +K+ Q+ EI
Sbjct: 824 RFFEFKRRQLVK-----LVNLEKDLVQQKDILKKEVQEEQEI 860
Score = 41.6 bits (96), Expect = 0.004
Identities = 81/372 (21%), Positives = 156/372 (41%), Gaps = 92/372 (24%)
Query: 656 ELEMWKEMQEDIFENQLK-QKELAHMQALAEEWKKRD----RERESLVKKKVAEYTILEG 710
E+E+ K+ QE+ E L+ Q+EL ++ L K +E + L K+K +Y LE
Sbjct: 689 EIELQKKRQEE--ETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLE- 745
Query: 711 KLQKTLIDLEKREQQL--ASVESELQREKKELQ----------SERQRNLQELQDSIRRA 758
L+K ++ +++EQ + A +E +L+ +++ +Q E +R+L+ +++S+ R
Sbjct: 746 -LEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRV 804
Query: 759 KEDCI----HQVELERLKIKQLEEDKHRLQQQLN---DAENKYKILEKEFQQFKD----- 806
KE ELE+ +++ E + +L + +N D + IL+KE Q+ ++
Sbjct: 805 KEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECL 864
Query: 807 QQNNKPEIRLQSEINLLTLEKVELERKLESA--TKSKLHYKQQWGRALKE-----LARLK 859
+ + E RL + + + E+ + E + +L YK++ + L + L K
Sbjct: 865 KCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEK 924
Query: 860 QR------------------------EQESQMARL------------------------- 870
QR E+E Q+A+
Sbjct: 925 QRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEE 984
Query: 871 ---KKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASG 927
KK++E LE + A E+ + ER+ R+ + +EQ+Q S S
Sbjct: 985 KVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSR 1044
Query: 928 KKDGPHGSVLEE 939
++ G S+ E
Sbjct: 1045 EQSGLQASLEAE 1056
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 66.6 bits (161), Expect = 1e-10
Identities = 76/341 (22%), Positives = 147/341 (43%), Gaps = 17/341 (4%)
Query: 600 VTLEDYGLVKMREIFISDSSQGVSAVQQKPSSLPPAPCPSEIQTEPRETLEYKAALELEM 659
+T ED ++M E S+ +S + L E + + E + E E
Sbjct: 259 ITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERER 318
Query: 660 WKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKTLIDL 719
+E +E E + +++ + E + RDR+R K++ + + +
Sbjct: 319 ERERREREREREREREREKEKERERERERDRDRDR---TKERDRDRDRERDRDRDRERSS 375
Query: 720 EKREQQLASVESELQREK-KELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIKQLEE 778
++ + + S E RE+ +E + ER+R + ++ R + + + E E+ K + EE
Sbjct: 376 DRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREE 435
Query: 779 D------KHRLQQQLNDAENKYKILEKEFQ---QFKDQQNNKPEIRLQSEINLLTLEKVE 829
D + +L+++L + E Y+ K ++ + K ++ K R + + E
Sbjct: 436 DEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495
Query: 830 LERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEE 889
L+ LE + K G AL++ R +++E E+ K+++EELE++R R LA
Sbjct: 496 LKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGH 555
Query: 890 KDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKD 930
D EL + E R RQ + KQ +S E K++
Sbjct: 556 PD----PDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQE 592
Score = 48.9 bits (115), Expect = 2e-05
Identities = 58/280 (20%), Positives = 122/280 (43%), Gaps = 18/280 (6%)
Query: 644 EPRETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVA 703
EP TL L + ++Q I E +L K A +A +EWK + + + +
Sbjct: 136 EPESTLR-----ALRLLHDLQ--IGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETV 188
Query: 704 EYTILEGKLQKTLIDLEKREQQLASVESELQRE-KKELQSERQRNLQELQDSIRRAKEDC 762
E ++T ++R+Q + L RE EL + Q + + + KED
Sbjct: 189 TNDDEEALDEET----KRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDI 244
Query: 763 IHQVELERLKIKQL--EEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEI 820
+ + L L +ED + ++ + E+K ++ +E +F+D E + + E
Sbjct: 245 FRRFPVAPLIPYPLITKEDINAIEME----EDKRDLISREISKFRDTHKKLEEEKGKKEK 300
Query: 821 NLLTLEKVELERKLESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQM 880
+EK ER+ E + + +++ +E + K+RE+E + R + + +E ++
Sbjct: 301 ERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRD 360
Query: 881 RLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQD 920
R R + ++R + E +R R++E+++ ++
Sbjct: 361 RDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERE 400
Score = 36.6 bits (83), Expect = 0.12
Identities = 31/139 (22%), Positives = 60/139 (43%), Gaps = 16/139 (11%)
Query: 640 EIQTEPRETLEYKAALELEMWKEMQEDI---------FENQLKQKELAHMQALAEEWKKR 690
E + E E + A E + KE ED + QK L + E +R
Sbjct: 476 EKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEA-DER 534
Query: 691 DRERESLVKKKVAEYTILEG------KLQKTLIDLEKREQQLASVESELQREKKELQSER 744
DR+RE +++ + + EG +LQ+ + E+R Q E E + E++E Q +
Sbjct: 535 DRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKE 594
Query: 745 QRNLQELQDSIRRAKEDCI 763
++ + +++ ++ C+
Sbjct: 595 EKREEPMEEEEEPEQKPCL 613
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 66.2 bits (160), Expect = 1e-10
Identities = 64/255 (25%), Positives = 138/255 (54%), Gaps = 19/255 (7%)
Query: 646 RETLEYKAALELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEY 705
RE E E EMW++ +E I E + K++E Q +K+ RE++ ++++ E
Sbjct: 377 REQDEKIQEQEEEMWRQ-EEKIREQEEKRQEKMWRQ------EKKMREQDEKIREQEEEM 429
Query: 706 TILEGKLQKTLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQ 765
E K+++ ++ +E++L VE ++Q E++++Q E++ +Q ++ I+ +E Q
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ-EQEEKIQRQEEKIQEQEEKTWRQ 488
Query: 766 VEL--ERLKIKQLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLL 823
+L + KI + EE R ++++ + E K + E++ Q+ ++++ + E+RL + +
Sbjct: 489 EKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR-QEEKMREQEVRLWQQEEKM 547
Query: 824 TLEKV---ELERKL-ESATKSKL---HYKQQWGRALKELARLKQREQESQMAR-LKKQQE 875
++V ELE +L + K++L ++ + L L + Q E +SQ A+ L++QQ+
Sbjct: 548 QEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQD 607
Query: 876 ELEQMRLRYLAAEEK 890
+Y+AA ++
Sbjct: 608 HYRGHLQQYVAAYQQ 622
Score = 58.2 bits (139), Expect = 4e-08
Identities = 57/313 (18%), Positives = 150/313 (47%), Gaps = 14/313 (4%)
Query: 656 ELEMWKEMQEDIFENQLKQKE-LAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQK 714
E E+W + + E +Q+E + + E + + RE+E + ++ + E K+++
Sbjct: 284 ENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIRE 343
Query: 715 TLIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIK 774
+ ++E+++ E ++ RE++E ++ ++E + I+ +E+ Q E R + +
Sbjct: 344 QEDKMWRQEEKIREQEEKI-REQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 775 QLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKL 834
+ +E R ++++ + + K + E+E + +++ E+ E L E+E K+
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR-----EVEEKM 457
Query: 835 ESATKSKLHYKQQWGRALKELARLKQREQESQMARLKKQQEELEQMRLRYLAAEEKDTVK 894
+ + +++ R +++ +Q E+ + +L KQ+E++ + + EEK
Sbjct: 458 QEEEEKMQEQEEKIQRQEEKIQ--EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK---M 512
Query: 895 TERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRLIEERDT 954
E++E + + E ++++QE+K + + ++ V + L++ L +L ++ +
Sbjct: 513 WEQEEKMQEQEE--KMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAEL 570
Query: 955 LMRTGVYNHEDRI 967
L G + R+
Sbjct: 571 LGGAGRESGSQRL 583
Score = 52.4 bits (124), Expect = 2e-06
Identities = 58/310 (18%), Positives = 147/310 (47%), Gaps = 26/310 (8%)
Query: 656 ELEMWKEMQEDIFENQLKQKELAHMQALAEEWKKRDRERESLVKKKVAEYTILEGKLQKT 715
E+ K + + E L M E+ K +R+ SL ++ TI + +L++
Sbjct: 164 EVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTK-ERDAPSL---ELYRNTITDEELKEK 219
Query: 716 LIDLEKREQQLASVESELQREKKELQSERQRNLQELQDSIRRAKEDCIHQVELERLKIK- 774
+L+++ + + S +SE+Q K+L+ + +R L + + D + + EL+ + K
Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGK-ELQSVSAKL 278
Query: 775 QLEEDKHRLQQQLNDAENKYKILEKEFQQFKDQQNNKPEIRLQSEINLLTLEKVELERKL 834
Q + +++ L LN + + ++E Q ++++ + E++++ + + ++ ++ +
Sbjct: 279 QAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQE 338
Query: 835 ESATKSKLHYKQQWGRALKELARLKQREQE---------SQMARLKKQQEELEQMRLRYL 885
E + + +Q + ++ +++++E++ Q ++++Q+EE+ + +
Sbjct: 339 EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR 398
Query: 886 AAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYL 945
EEK K RQE +R + ++R+QE++ ++ +I LEE + D
Sbjct: 399 EQEEKRQEKMWRQE-KKMREQDEKIREQEEEMWRQEEKIRE----------LEEMMQDQE 447
Query: 946 TRLIEERDTL 955
+L E + +
Sbjct: 448 EKLREVEEKM 457
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,607,983
Number of Sequences: 37866
Number of extensions: 1771759
Number of successful extensions: 19702
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 312
Number of HSP's successfully gapped in prelim test: 1306
Number of HSP's that attempted gapping in prelim test: 8603
Number of HSP's gapped (non-prelim): 5963
length of query: 986
length of database: 18,247,518
effective HSP length: 112
effective length of query: 874
effective length of database: 14,006,526
effective search space: 12241703724
effective search space used: 12241703724
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.