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Search of human proteins with 94721327
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|94721327 basonuclin 2 [Homo sapiens]
(1099 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94721327 basonuclin 2 [Homo sapiens] 2239 0.0
gi|157276588 basonuclin 1 [Homo sapiens] 754 0.0
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 52 3e-06
gi|24308069 zinc finger protein 521 [Homo sapiens] 50 9e-06
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 48 4e-05
gi|9945318 MAX binding protein [Homo sapiens] 46 2e-04
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 46 2e-04
gi|153792074 proline rich 12 [Homo sapiens] 45 4e-04
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi... 44 8e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 43 0.002
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 43 0.002
gi|69885084 p120E4F [Homo sapiens] 43 0.002
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom... 42 0.002
gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens] 42 0.003
gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens] 42 0.003
gi|148539870 histone deacetylase 7 isoform d [Homo sapiens] 42 0.003
gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo sap... 42 0.003
gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo sa... 42 0.003
gi|189217876 sal-like 1 isoform b [Homo sapiens] 42 0.003
gi|118442837 sal-like 1 isoform a [Homo sapiens] 42 0.003
gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens] 42 0.003
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 42 0.003
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 42 0.003
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 42 0.003
gi|46359075 zinc finger protein 423 [Homo sapiens] 42 0.004
gi|16445033 ACRC protein [Homo sapiens] 42 0.004
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 42 0.004
gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Hom... 41 0.005
gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo... 41 0.005
gi|239747212 PREDICTED: hypothetical protein XP_002346939 [Homo ... 41 0.007
>gi|94721327 basonuclin 2 [Homo sapiens]
Length = 1099
Score = 2239 bits (5803), Expect = 0.0
Identities = 1099/1099 (100%), Positives = 1099/1099 (100%)
Query: 1 MAHLGPTPPPHSLNYKSEDRLSEQDWPAYFKVPCCGVDTSQIESEEAEVDVRERETQRDR 60
MAHLGPTPPPHSLNYKSEDRLSEQDWPAYFKVPCCGVDTSQIESEEAEVDVRERETQRDR
Sbjct: 1 MAHLGPTPPPHSLNYKSEDRLSEQDWPAYFKVPCCGVDTSQIESEEAEVDVRERETQRDR 60
Query: 61 EPKRARDLTLRDSCTDNSMQFGTRTTTAEPGFMGTWQNADTNLLFRMSQQAIRCTLVNCT 120
EPKRARDLTLRDSCTDNSMQFGTRTTTAEPGFMGTWQNADTNLLFRMSQQAIRCTLVNCT
Sbjct: 61 EPKRARDLTLRDSCTDNSMQFGTRTTTAEPGFMGTWQNADTNLLFRMSQQAIRCTLVNCT 120
Query: 121 CECFQPGKINLRTCDQCKHGWVAHALDKLSTQHLYHPTQVEIVQSNVVFDISSLMLYGTQ 180
CECFQPGKINLRTCDQCKHGWVAHALDKLSTQHLYHPTQVEIVQSNVVFDISSLMLYGTQ
Sbjct: 121 CECFQPGKINLRTCDQCKHGWVAHALDKLSTQHLYHPTQVEIVQSNVVFDISSLMLYGTQ 180
Query: 181 AVPVRLKILLDRLFSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRWAIMSREE 240
AVPVRLKILLDRLFSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRWAIMSREE
Sbjct: 181 AVPVRLKILLDRLFSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRWAIMSREE 240
Query: 241 EIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTFIESNNRTRSPSLLAH 300
EIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTFIESNNRTRSPSLLAH
Sbjct: 241 EIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTFIESNNRTRSPSLLAH 300
Query: 301 LENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLGLPPNGLLLEQPGLRLREPSLSTQ 360
LENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLGLPPNGLLLEQPGLRLREPSLSTQ
Sbjct: 301 LENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLGLPPNGLLLEQPGLRLREPSLSTQ 360
Query: 361 NEYNESSESEVSPTPYKNDQTPNRNALTSITNVEPKTEPACVSPIQNSAPVSDLTKTEHP 420
NEYNESSESEVSPTPYKNDQTPNRNALTSITNVEPKTEPACVSPIQNSAPVSDLTKTEHP
Sbjct: 361 NEYNESSESEVSPTPYKNDQTPNRNALTSITNVEPKTEPACVSPIQNSAPVSDLTKTEHP 420
Query: 421 KSSFRIHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVF 480
KSSFRIHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVF
Sbjct: 421 KSSFRIHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVF 480
Query: 481 SSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLALTSPGRPPMG 540
SSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLALTSPGRPPMG
Sbjct: 481 SSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLALTSPGRPPMG 540
Query: 541 FTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGT 600
FTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGT
Sbjct: 541 FTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGT 600
Query: 601 IEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDP 660
IEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDP
Sbjct: 601 IEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDP 660
Query: 661 NDGGAVVNDMSHDNHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRRADSMTSEDQEPER 720
NDGGAVVNDMSHDNHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRRADSMTSEDQEPER
Sbjct: 661 NDGGAVVNDMSHDNHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRRADSMTSEDQEPER 720
Query: 721 DYENESESSEPKLGEESMEGDEHIHSEVSEKVLMNSERPDENHSEPSHQDVIKVKEEFTD 780
DYENESESSEPKLGEESMEGDEHIHSEVSEKVLMNSERPDENHSEPSHQDVIKVKEEFTD
Sbjct: 721 DYENESESSEPKLGEESMEGDEHIHSEVSEKVLMNSERPDENHSEPSHQDVIKVKEEFTD 780
Query: 781 PTYDMFYMSQYGLYNGGGASMAALHESFTSSLNYGSPQKFSPEGDLCSSPDPKICYVCKK 840
PTYDMFYMSQYGLYNGGGASMAALHESFTSSLNYGSPQKFSPEGDLCSSPDPKICYVCKK
Sbjct: 781 PTYDMFYMSQYGLYNGGGASMAALHESFTSSLNYGSPQKFSPEGDLCSSPDPKICYVCKK 840
Query: 841 SFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINLHRKLLTKELDDMG 900
SFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINLHRKLLTKELDDMG
Sbjct: 841 SFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINLHRKLLTKELDDMG 900
Query: 901 LDSSQPSLSKDLRDEFLVKIYGAQHPMGLDVREDASSPAGTEDSHLNGYGRGMAEDYMVL 960
LDSSQPSLSKDLRDEFLVKIYGAQHPMGLDVREDASSPAGTEDSHLNGYGRGMAEDYMVL
Sbjct: 901 LDSSQPSLSKDLRDEFLVKIYGAQHPMGLDVREDASSPAGTEDSHLNGYGRGMAEDYMVL 960
Query: 961 DLSTTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESAHKAEAPALPGSLGAEVS 1020
DLSTTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESAHKAEAPALPGSLGAEVS
Sbjct: 961 DLSTTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESAHKAEAPALPGSLGAEVS 1020
Query: 1021 GSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSR 1080
GSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSR
Sbjct: 1021 GSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSR 1080
Query: 1081 NRHSQNPNLHKNIPFTSVD 1099
NRHSQNPNLHKNIPFTSVD
Sbjct: 1081 NRHSQNPNLHKNIPFTSVD 1099
>gi|157276588 basonuclin 1 [Homo sapiens]
Length = 994
Score = 754 bits (1947), Expect = 0.0
Identities = 454/1013 (44%), Positives = 604/1013 (59%), Gaps = 80/1013 (7%)
Query: 106 RMSQQAIRCTLVNCTCECFQPGKINLRTCDQCKHGWVAHALDKLSTQHLYHPTQVEIVQS 165
R +AI CTL NC+C+ F+PGKIN R CDQCKHGWVAHAL KL +Y +QVEIVQS
Sbjct: 29 RRMAEAISCTL-NCSCQSFKPGKINHRQCDQCKHGWVAHALSKLRIPPMYPTSQVEIVQS 87
Query: 166 NVVFDISSLMLYGTQAVPVRLKILLDRLFSVLKQEEVLHILHGLGWTLRDYVRGYILQDA 225
NVVFDISSLMLYGTQA+PVRLKILLDRLFSVLKQ+EVL ILH L WTL+DY+RGY+LQDA
Sbjct: 88 NVVFDISSLMLYGTQAIPVRLKILLDRLFSVLKQDEVLQILHALDWTLQDYIRGYVLQDA 147
Query: 226 AGKVLDRWAIMSREEEIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTF 285
+GKVLD W+IM+ EEE+ TLQQFLRFGETKSIVELMAIQEKE Q++ +P S + DIR F
Sbjct: 148 SGKVLDHWSIMTSEEEVATLQQFLRFGETKSIVELMAIQEKEEQSIIIPPSTANVDIRAF 207
Query: 286 IESNNRTRSPSLLAHLENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLGLPPNGLLL 345
IES + RS SL ++ NPSSIH FEN+ +++ F+LPFQ+ NP+ L+G P +L
Sbjct: 208 IESCSH-RSSSLPTPVDKGNPSSIHPFENLISNMTFMLPFQFFNPLPPALIGSLPEQYML 266
Query: 346 EQPGLRLREPSLSTQNEYNESSESEVSPTPYKNDQTPNRNALTSITNVEPKTEPACVSPI 405
EQ + ++P + +SS S TP++ ++ N +IT E T +
Sbjct: 267 EQGHDQSQDPKQEVHGPFPDSSFLTSSSTPFQVEKDQCLNCPDAITKKEDSTH------L 320
Query: 406 QNSAPVSDLTKTEHPKSSFRIH-RMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVH 464
+S+ + +TK E + S + R ++KGRVFC AC KTFYDKGTLKIHYNAVH
Sbjct: 321 SDSSSYNIVTKFERTQLSPEAKVKPERNSLGTKKGRVFCTACEKTFYDKGTLKIHYNAVH 380
Query: 465 LKIKHRCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIAS 524
LKIKH+CTIEGCNMVFSSLRSRNRHSANPNPRLHMPM RNNRDKDL + + A++
Sbjct: 381 LKIKHKCTIEGCNMVFSSLRSRNRHSANPNPRLHMPMNRNNRDKDLRNSLNLASSENYKC 440
Query: 525 TKSNLALTSPG-RPPMGFTTPPLD----PVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTP 579
+TSP RPP + D P N + ++F LKTVQPV PFYRS TP
Sbjct: 441 --PGFTVTSPDCRPPPSYPGSGEDSKGQPAFPNIGQNGVLFPNLKTVQPVLPFYRSPATP 498
Query: 580 GEMVSPPTSLPTSPIIPTSGTIEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMP 639
E+ + P LP+ P++ +S +P +++ P D PKKK RKSSMP
Sbjct: 499 AEVANTPGILPSLPLLSSS--------------IPEQLISNEMP-FDALPKKKSRKSSMP 543
Query: 640 VKIEKEIIDTADE----FDDEDDDP-----NDGGAVVNDMSHDNHCHSQEEMSPGMSVKD 690
+KIEKE ++ A+E ++D P D + SH ++ + G K
Sbjct: 544 IKIEKEAVEIANEKRHNLSSDEDMPLQVVSEDEQEACSPQSH--RVSEEQHVQSGGLGKP 601
Query: 691 FSKHNRTRCISRTEIRRADSMTSEDQEPERDYENESESSEPKLGEESMEGDEHIHSEVSE 750
F + R C + I + +++ ++ + E E+E + P L E ++ H
Sbjct: 602 FPEGERP-CHRESVIESSGAISQTPEQATHNSERETEQT-PALIMVPREVEDGGH----- 654
Query: 751 KVLMNSERPDENHSEPSHQDVIKVKEEFTDPTYDMFYMSQYGLYNGGGASMAALHESFTS 810
E++ P + + ++ + + + + G + L +S
Sbjct: 655 ----------EHYFTPGMEPQVPF-SDYMELQQRLLAGGLFSALSNRGMAFPCLEDS--K 701
Query: 811 SLNYGSPQKFSPEGDLCSSPDPKICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNA 870
L + + + + C +CKK+FK++ SVK+H++N+H+KEMH CTV GCNA
Sbjct: 702 ELEHVGQHALARQ----IEENRFQCDICKKTFKNACSVKIHHKNMHVKEMHTCTVEGCNA 757
Query: 871 AFPSRRSRDRHSANINLHRKLLTKELDDMGLDSSQPS-LSKDLRDEFLVKIYGAQHPMGL 929
FPSRRSRDRHS+N+NLH+K L++E + D + + L KD+ E + Q
Sbjct: 758 TFPSRRSRDRHSSNLNLHQKALSQEALESSEDHFRAAYLLKDVAKEAYQDVAFTQQASQT 817
Query: 930 DVREDASSPAGT--------EDSHLNGYGRGMAEDYMVLDLSTTSSLQSSSSIHSSRESD 981
V +S G+ + L Y G + +LDLSTTSS++S SS HSS +SD
Sbjct: 818 SVIFKGTSRMGSLVYPITQVHSASLESYNSGPLSEGTILDLSTTSSMKSESSSHSSWDSD 877
Query: 982 AGSDEG-ILLDDIDGASDSGESAHKAEAPALPGSLGAEVSGSLMFSSLSGSNGGIMCNIC 1040
S+EG +L++D DG + G S E P + E + + S SG I C++C
Sbjct: 878 GVSEEGTVLMEDSDGNCE-GSSLVPGE-DEYPICVLMEKADQSLASLPSGL--PITCHLC 933
Query: 1041 HKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSRNRHSQNPNLHKNI 1093
K YSNKGT R HYKTVHLR++HKCKVPGCN MFSSVRSRNRHSQNPNLHK++
Sbjct: 934 QKTYSNKGTFRAHYKTVHLRQLHKCKVPGCNTMFSSVRSRNRHSQNPNLHKSL 986
Score = 87.4 bits (215), Expect = 7e-17
Identities = 36/69 (52%), Positives = 48/69 (69%)
Query: 1026 SSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSRNRHSQ 1085
+SL G + C C K + +KGTL++HY VHL+ HKC + GCNM+FSS+RSRNRHS
Sbjct: 348 NSLGTKKGRVFCTACEKTFYDKGTLKIHYNAVHLKIKHKCTIEGCNMVFSSLRSRNRHSA 407
Query: 1086 NPNLHKNIP 1094
NPN ++P
Sbjct: 408 NPNPRLHMP 416
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 52.0 bits (123), Expect = 3e-06
Identities = 52/217 (23%), Positives = 75/217 (34%), Gaps = 56/217 (25%)
Query: 534 PGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSP 593
P PP G T PP+ P +G T P P P E+ + P LP
Sbjct: 799 PPPPPSGATPPPIAP------------TGPPTASPPVPAKEE---PEELPAAPGPLP--- 840
Query: 594 IIPTSGTIEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMPVKIEKEIIDTADEF 653
PPPP P VP + P L P+ P P E + +
Sbjct: 841 -----------PPPPPPPPVPGPVTL---PPPQLVPEGTPGGGGPPALEEDLTVININSS 886
Query: 654 DDEDDDPNDGGAVVNDMSHDNHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRRADSMTS 713
D+E+++ + +EE +DF + E +
Sbjct: 887 DEEEEEEEE--------------EEEEEEEEEEEEEDFEE----------EEEDEEEYFE 922
Query: 714 EDQEPERDYENESESSEPKLGEESMEGDEHIHSEVSE 750
E++E E ++E E E E +L EE E DE E+ E
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEE 959
Score = 32.0 bits (71), Expect = 3.3
Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 4/68 (5%)
Query: 710 SMTSEDQEPERDYENESESSEPKLGEESMEGDEHIHSEVSEKVLMNSERPDENHSEPSHQ 769
++ S D+E E + E E E E + EE E +E E E+ E +E E +
Sbjct: 882 NINSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE----EDEEEYFEEEEEEEEEFEEEFEE 937
Query: 770 DVIKVKEE 777
+ +++EE
Sbjct: 938 EEGELEEE 945
>gi|24308069 zinc finger protein 521 [Homo sapiens]
Length = 1311
Score = 50.4 bits (119), Expect = 9e-06
Identities = 60/262 (22%), Positives = 104/262 (39%), Gaps = 21/262 (8%)
Query: 835 CYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINL------H 888
C +C++ F S S++LH H E V CN F + H + +L H
Sbjct: 724 CTLCQEVFDSKVSIQLHLAVKHSNEKKVYRCTSCNWDFRNETDLQLHVKHNHLENQGKVH 783
Query: 889 RKLLTKEL--DDMGLDSSQPSLSKDLRDEFLVKIYGAQHPMGLDVRE-DASSPAGTEDSH 945
+ + E ++ L + SK +F K + A + +RE T +
Sbjct: 784 KCIFCGESFGTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFETKTPNCG 843
Query: 946 LNGYGRGMAEDYMVLDLSTTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESA-- 1003
NG + ++ + L T+S +S +S H E D + E + DI GA+ + E+
Sbjct: 844 TNGASEQVQKEEVELQTLLTNSQESHNS-HDGSEEDVDTSEPMYGCDICGAAYTMETLLQ 902
Query: 1004 -HKAEAPAL-PGSLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLRE 1061
H+ + PG +++ G CN+C + + ++ LR H +T HL
Sbjct: 903 NHQLRDHNIRPG------ESAIVKKKAELIKGNYKCNVCSRTFFSENGLREHMQT-HLGP 955
Query: 1062 MHKCKVPGCNMMFSSVRSRNRH 1083
+ P C F S+ + H
Sbjct: 956 VKHYMCPICGERFPSLLTLTEH 977
Score = 38.1 bits (87), Expect = 0.046
Identities = 61/272 (22%), Positives = 97/272 (35%), Gaps = 53/272 (19%)
Query: 832 PKICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINLH--- 888
P C C KSF +K H ++ K CT C+ F +RSRDRH I LH
Sbjct: 117 PYPCQFCDKSFSRLSYLKHHEQSHSDKLPFKCTY--CSRLFKHKRSRDRH---IKLHTGD 171
Query: 889 RKLLTKELDDMGLDSSQPSLSKDLRDEFLVKIYGAQHPMGLDVREDASSPAGTEDSHLNG 948
+K E D + S+ + +K + + P +
Sbjct: 172 KKYHCSECD--------AAFSRSDHLKIHLKTHTSNKPYKCAICR--------------- 208
Query: 949 YGRGMAEDYMVLDLSTTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESAHKAEA 1008
RG ++SSL +H + GS G ++D D+ + + E
Sbjct: 209 --RGFL---------SSSSLHGHMQVHERNKD--GSQSGSRMEDWK-MKDTQKCSQCEEG 254
Query: 1009 PALPGSLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLRE-MHKCKV 1067
P L ++ S + + C CH+++ + +L H + VH E + C +
Sbjct: 255 FDFPEDLQKHIAECHPECSPNEDRAALQCVYCHELFVEETSLMNHMEQVHSGEKKNSCSI 314
Query: 1068 PGCNMMFSSVRSRNRH---SQNPNL--HKNIP 1094
C+ F +V H Q P H N P
Sbjct: 315 --CSESFHTVEELYSHMDSHQQPESCNHSNSP 344
Score = 32.3 bits (72), Expect = 2.5
Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 443 CNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRH 489
C C K+F LK H + K+ +CT C+ +F RSR+RH
Sbjct: 120 CQFCDKSFSRLSYLKHHEQSHSDKLPFKCTY--CSRLFKHKRSRDRH 164
Score = 31.6 bits (70), Expect = 4.3
Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 3/61 (4%)
Query: 438 KGRVFCNACGKTFYDKGTLKIHYNAVHLKIKH-RCTIEGCNMVFSSLRSRNRHSANPNPR 496
KG CN C +TF+ + L+ H +KH C I C F SL + H +
Sbjct: 927 KGNYKCNVCSRTFFSENGLREHMQTHLGPVKHYMCPI--CGERFPSLLTLTEHKVTHSKS 984
Query: 497 L 497
L
Sbjct: 985 L 985
Score = 30.4 bits (67), Expect = 9.6
Identities = 26/96 (27%), Positives = 45/96 (46%), Gaps = 16/96 (16%)
Query: 1008 APALPGSLG----AEVSGSLMFSSLSGSNGGIMCNICHK-MYSNKGTLRVHYKTVHL--- 1059
AP +P S G A+ + + S + C C+K ++S+ L++H KT+HL
Sbjct: 374 APPIPKSRGRKRAAQQTPDMTGPSSKQAKVTYSCIYCNKQLFSSLAVLQIHLKTMHLDKP 433
Query: 1060 REMHKCKVPGCNMMFSSVRSRNRH------SQNPNL 1089
+ H C+ C + S+ + N H +Q+P L
Sbjct: 434 EQAHICQY--CLEVLPSLYNLNEHLKQVHEAQDPGL 467
Score = 30.4 bits (67), Expect = 9.6
Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 12/73 (16%)
Query: 443 CNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRHSANPNPRLHMPML 502
C +C K F L+ H +H + RCT+ C VF S S H A +
Sbjct: 696 CESCDKQFTSVDDLQKHLLDMHTFVFFRCTL--CQEVFDSKVSIQLHLA----------V 743
Query: 503 RNNRDKDLIRATS 515
+++ +K + R TS
Sbjct: 744 KHSNEKKVYRCTS 756
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 48.1 bits (113), Expect = 4e-05
Identities = 41/151 (27%), Positives = 65/151 (43%), Gaps = 22/151 (14%)
Query: 628 APKKKPRKSSMPVKIEKEIIDTADEFD---DEDDDPNDGGAVVNDMSHDNHCHSQEEMSP 684
APK+KP VK + +D D+ D D D+ D G + S DN P
Sbjct: 72 APKRKP----FAVKADSSSVDECDDSDGTEDMDEKEEDEG---EEYSEDND-------EP 117
Query: 685 GMSVKDFSKHNRTRCISRTEIRRADSMTSEDQEPERDYENESESSEPKLGEESMEGDEHI 744
G ++ + +R EI D ED E D E E E E + EE E ++H
Sbjct: 118 GDEDEEDEEGDREE---EEEIEEEDEDDDEDGEDVEDEEEEEEEEEEE--EEEEENEDHQ 172
Query: 745 HSEVSEKVLMNSERPDENHSEPSHQDVIKVK 775
+ + +++ ++E+ D N+ E + D + K
Sbjct: 173 MNCHNTRIMQDTEKDDNNNDEYDNYDELVAK 203
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 45.8 bits (107), Expect = 2e-04
Identities = 58/262 (22%), Positives = 100/262 (38%), Gaps = 33/262 (12%)
Query: 534 PGRPPMGFTTPPLD----PVLQN---PLPSQLVFSGLKTVQPVPPFYRSLL-TPGEMVSP 585
P PP T PL PV+ N PLP P+ P +L+ PG +
Sbjct: 74 PAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKE 133
Query: 586 PTSLPTSPIIPTSGTI---------EQHPPPPSEPVVPAVMMATHEPSA--DLAPKKKPR 634
P LP+ P +PT + P P +P+ V+ P LAP++ P
Sbjct: 134 PAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQPPP 193
Query: 635 KSSMPVKIEKEIIDTADEFDDEDDDPNDGG----AVVNDMSHDNHCHSQE--EMSPGMSV 688
+ +K+ A+E + GG V N + + H +E E
Sbjct: 194 PTLGTLKLA-----PAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIP 248
Query: 689 KDFSKHNRTRCISRTEIRRADSMTSEDQEPERDYE---NESESSEPKLGEESMEGDEHIH 745
K + RT +R S+ +++E E + E E +++ +L E E + +
Sbjct: 249 NVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMD 308
Query: 746 SEVSEKVLMNSERPDENHSEPS 767
++VL + +P+++ + S
Sbjct: 309 VLEIDRVLRQTGQPEDDQASTS 330
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 45.8 bits (107), Expect = 2e-04
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 8/88 (9%)
Query: 532 TSPGRP-PMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSL- 589
T PG+P P G PPL PLP L + +QPVPP L P V P L
Sbjct: 719 TGPGQPAPPGQQPPPL--AQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLK 776
Query: 590 ----PTSPIIPTSGTIEQHPPPPSEPVV 613
P +P+ P + Q PP P P +
Sbjct: 777 PLQMPQAPLQPLAQVPPQMPPIPVVPPI 804
Score = 41.6 bits (96), Expect = 0.004
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 3/115 (2%)
Query: 518 ATPVIASTKSNLALTS-PGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSL 576
A P +A+ + A+ PG+P P + P P P V ++ P P
Sbjct: 890 APPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTV-QNMRATPPQPALPPQP 948
Query: 577 LTPGEMVSPPT-SLPTSPIIPTSGTIEQHPPPPSEPVVPAVMMATHEPSADLAPK 630
P + V PP +LP P++P T P P +P++P + +P+ + P+
Sbjct: 949 TLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPE 1003
Score = 31.6 bits (70), Expect = 4.3
Identities = 31/114 (27%), Positives = 41/114 (35%), Gaps = 7/114 (6%)
Query: 517 AATPVIASTKSNLALTSPGRPPMGFTTPPLDPVL--QNPLPSQLVFSGLKTVQPVPPFYR 574
AA P +A T SP P P L Q LP Q V T+ P P
Sbjct: 914 AAFPQMAPTD---VPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPP 970
Query: 575 SLLTPGEMVSPPTS-LPTSPIIPTSGTIEQHPPPPSEPVVPAVMMATHEPSADL 627
P + V PP LP P++P + P P +P +P P + +
Sbjct: 971 QPTRPPQPVLPPQPMLPPQPVLPPQPALPVR-PEPLQPHLPEQAAPAATPGSQI 1023
Score = 30.8 bits (68), Expect = 7.4
Identities = 34/134 (25%), Positives = 44/134 (32%), Gaps = 19/134 (14%)
Query: 533 SPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSP------- 585
+PG P P P LQ P + V P PP PG+ P
Sbjct: 678 APGLPVGSVPAPACPPSLQQHFPDPAM--SFAPVLP-PPSTPMPTGPGQPAPPGQQPPPL 734
Query: 586 --PTSLPT----SPIIPTSGTIEQHPP---PPSEPVVPAVMMATHEPSADLAPKKKPRKS 636
PT LP P++P PP P S+ PA + P A L P +
Sbjct: 735 AQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQ 794
Query: 637 SMPVKIEKEIIDTA 650
P+ + I A
Sbjct: 795 MPPIPVVPPITPLA 808
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 45.1 bits (105), Expect = 4e-04
Identities = 37/144 (25%), Positives = 56/144 (38%), Gaps = 10/144 (6%)
Query: 530 ALTSPGRPPM---------GFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPG 580
A PG PP+ G PPL P P + P PP +L +P
Sbjct: 1427 AAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPP 1486
Query: 581 EMVSPPTSLPTSPIIPTSGTIEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMPV 640
+V+P S P P +P PPP P A + A E A +P+ + P+
Sbjct: 1487 PLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPL 1546
Query: 641 KIEKEIIDTADEFDDEDDDPNDGG 664
+ K+ +TA + D++ + G
Sbjct: 1547 HLAKK-QETAAVCGETDEEAGESG 1569
Score = 36.6 bits (83), Expect = 0.13
Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 7/52 (13%)
Query: 563 LKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGTIEQHPPPPSEPVVP 614
LK+ + PP Y++ LTP +SPP S+P P +P G P PP+ P VP
Sbjct: 1289 LKSGKRHPPLYQAGLTPP--LSPPKSVP--PSVPARGL---QPQPPATPAVP 1333
Score = 32.0 bits (71), Expect = 3.3
Identities = 36/131 (27%), Positives = 49/131 (37%), Gaps = 15/131 (11%)
Query: 515 SGAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLV----FSGLKTVQPVP 570
S A +P +++K + L P PP P P+P QL GL+ P P
Sbjct: 807 SHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP 866
Query: 571 PFYRSLLTPGEMVSPPTSL-----PTSPIIPTSGTIEQHPPPPSEPVVPAVMMATHEPSA 625
L P E + PP ++ P+ P G PP SE PA + P
Sbjct: 867 -----RLRPEESLDPPGAMQELLGALEPLPPAPGDTGV-GPPNSEGKDPAGAYRSPSPQG 920
Query: 626 DLAPKKKPRKS 636
AP+ P S
Sbjct: 921 TKAPRFVPLTS 931
Score = 30.8 bits (68), Expect = 7.4
Identities = 40/169 (23%), Positives = 59/169 (34%), Gaps = 30/169 (17%)
Query: 516 GAATPVI---ASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSG----LKTVQP 568
G AT V+ A K A PP PP P P L+ L V P
Sbjct: 741 GLATSVVHYGAGAKELGAFLQKSPPP-----PPPTAQSTQPTPHGLLLEAGGPDLPLVLP 795
Query: 569 VPPFYRSLLTPGEMVSPPTSLPTSPIIPT--------SGTIEQHPPPPSEPVVPAVMMAT 620
PP L P + P+ P++ + G + PPPP P + +
Sbjct: 796 PPP---PQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEA 852
Query: 621 H------EPSADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDPNDG 663
H EP+A +P+ +P +S P +E++ + D G
Sbjct: 853 HLRSHGLEPAAP-SPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVG 900
>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
sapiens]
Length = 729
Score = 43.9 bits (102), Expect = 8e-04
Identities = 48/183 (26%), Positives = 71/183 (38%), Gaps = 37/183 (20%)
Query: 516 GAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRS 575
G+ +PV+ + + +SPG P P Q PL + + +V PVPP
Sbjct: 296 GSQSPVVPAGAVSTGSSSPGTP---------QPAPQLPLNA----APPSSVPPVPP---- 338
Query: 576 LLTPGEMVSPPTSLPTSP---------IIPTSGTIEQHPPPPSEPVVPAVMMATHEPSAD 626
PP + P++P + TS E PPPP EPV A AT + D
Sbjct: 339 -----SEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPP-EPVPAAEGPATVQSVED 392
Query: 627 LAPKKKPRKS----SMPVKIEKEI-IDTADEFDDEDDDPNDGGAVVNDMSHDNHCHSQEE 681
P + +S + P + EK++ A + D D + G +V D Q
Sbjct: 393 FVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPR 452
Query: 682 MSP 684
SP
Sbjct: 453 GSP 455
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 42.7 bits (99), Expect = 0.002
Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 11/128 (8%)
Query: 518 ATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLL 577
A P +A+ + + P PPM +P P Q P P L L+ +P P +L
Sbjct: 470 APPSLAAPPLQVPPSPPASPPM---SPSATPPPQAPPP--LAAPPLQLAKPPPQAPPALA 524
Query: 578 TPG--EMVSPPTSLPTSPIIPTSGTIEQHP---PPPSEPVVPAVMMATHEPSADLAPK-K 631
TP + SPP S P S ++ P PPP P V A + PS +P +
Sbjct: 525 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 584
Query: 632 KPRKSSMP 639
PR+ P
Sbjct: 585 APRRPPTP 592
Score = 30.8 bits (68), Expect = 7.4
Identities = 40/161 (24%), Positives = 58/161 (36%), Gaps = 13/161 (8%)
Query: 489 HSANPNPR----LHMPMLRNNRDKDLIRATSGAATPVIASTKSNLALTSPGRPPMGFT-- 542
H + P P+ L P + R KD A ++ +A+ + AL S P + T
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPR-KDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326
Query: 543 TPPLDPVLQNPLP----SQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTS 598
+ L L PLP S L+T+ P S T + PT T +P+
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS--LGSPTLQATHSFLPSP 384
Query: 599 GTIEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMP 639
PPP P A+ PS +P P + P
Sbjct: 385 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 425
Score = 30.8 bits (68), Expect = 7.4
Identities = 33/128 (25%), Positives = 43/128 (33%), Gaps = 23/128 (17%)
Query: 529 LALTSPGRPPMGFTTPPLDPV---------------LQNPL------PSQLVFSGLKTVQ 567
LAL PP +PPL P+ LQ P P Q FS +
Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 459
Query: 568 PVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGTIEQHPPPPSEP--VVPAVMMATHEPSA 625
P P + +PP +P SP + PPP + P P + +A P A
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519
Query: 626 DLAPKKKP 633
A P
Sbjct: 520 PPALATPP 527
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 42.7 bits (99), Expect = 0.002
Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 11/128 (8%)
Query: 518 ATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLL 577
A P +A+ + + P PPM +P P Q P P L L+ +P P +L
Sbjct: 431 APPSLAAPPLQVPPSPPASPPM---SPSATPPPQAPPP--LAAPPLQLAKPPPQAPPALA 485
Query: 578 TPG--EMVSPPTSLPTSPIIPTSGTIEQHP---PPPSEPVVPAVMMATHEPSADLAPK-K 631
TP + SPP S P S ++ P PPP P V A + PS +P +
Sbjct: 486 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 545
Query: 632 KPRKSSMP 639
PR+ P
Sbjct: 546 APRRPPTP 553
Score = 32.0 bits (71), Expect = 3.3
Identities = 39/154 (25%), Positives = 53/154 (34%), Gaps = 29/154 (18%)
Query: 489 HSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLALTSPGRPPMGFTTPPLDP 548
H + P P+ L+ R + AA + + S LA SP PP P L
Sbjct: 259 HPSQPKPK----GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314
Query: 549 VLQNPL--PSQLVFS-GLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGTIEQHP 605
+ P PSQ S G T+Q F LP+ P+ P +
Sbjct: 315 LPSPPATPPSQATTSLGSPTLQATHSF----------------LPSPPLSPLA------T 352
Query: 606 PPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMP 639
PPP P A+ PS +P P + P
Sbjct: 353 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 386
Score = 30.8 bits (68), Expect = 7.4
Identities = 33/128 (25%), Positives = 43/128 (33%), Gaps = 23/128 (17%)
Query: 529 LALTSPGRPPMGFTTPPLDPV---------------LQNPL------PSQLVFSGLKTVQ 567
LAL PP +PPL P+ LQ P P Q FS +
Sbjct: 361 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420
Query: 568 PVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGTIEQHPPPPSEP--VVPAVMMATHEPSA 625
P P + +PP +P SP + PPP + P P + +A P A
Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480
Query: 626 DLAPKKKP 633
A P
Sbjct: 481 PPALATPP 488
>gi|69885084 p120E4F [Homo sapiens]
Length = 784
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 5/84 (5%)
Query: 1006 AEAPALPGSLGAEVSGS---LMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREM 1062
AEAP P G ++G L +G +C +CHK + L+ H T R+
Sbjct: 160 AEAPGSPRQQGLGLAGEGEQAQVKLLVNKDGRYVCALCHKTFKTGSILKAHMVTHSSRKD 219
Query: 1063 HKCKVPGCNMMF--SSVRSRNRHS 1084
H+CK+ G + S +R RH+
Sbjct: 220 HECKLCGASFRTKGSLIRHHRRHT 243
Score = 31.2 bits (69), Expect = 5.6
Identities = 15/48 (31%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 834 ICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRH 881
+C +C K+FK+ +K H ++ H C + C A+F ++ S RH
Sbjct: 193 VCALCHKTFKTGSILKAHMVTHSSRKDHECKL--CGASFRTKGSLIRH 238
Score = 30.4 bits (67), Expect = 9.6
Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 8/140 (5%)
Query: 443 CNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRHSANPNPRLHMPML 502
C CG +F KG+L H+ + ++C+ C F + RH + P
Sbjct: 222 CKLCGASFRTKGSLIRHHRRHTDERPYKCS--KCGKSFRESGALTRHLKSLTPCTEKIRF 279
Query: 503 RNNRD----KDLIRATSGA-ATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQN-PLPS 556
++D K+ RA SGA A + +T S P + T V+ +
Sbjct: 280 SVSKDVVVSKEDARAGSGAGAAGLGTATSSVTGEPIETSPVIHLVTDAKGTVIHEVHVQM 339
Query: 557 QLVFSGLKTVQPVPPFYRSL 576
Q + G+K + P PP + L
Sbjct: 340 QELSLGMKALAPEPPVSQEL 359
>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
1 isoform c [Homo sapiens]
Length = 1450
Score = 42.4 bits (98), Expect = 0.002
Identities = 40/153 (26%), Positives = 61/153 (39%), Gaps = 33/153 (21%)
Query: 541 FTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGT 600
F +PP+ PLP+ GL P+PP RS L P +P T+ P P++P
Sbjct: 89 FRSPPVPATPPEPLPTTTEDEGLPAAPPIPP-RRSCLPPTCFTTPSTAAP-DPVLPPL-P 145
Query: 601 IEQH------PPPPSEPVVPAVMMA--------------------THEPSADL--APKKK 632
++H PP P P ++++ + EP + L P +
Sbjct: 146 AKRHLAELSVPPVPPRTGPPRLLVSLPTKEEESLLPSLSSPPQPQSEEPLSTLPQGPPQP 205
Query: 633 PRKSSMPVKIEKEIIDTADEFDDEDDD--PNDG 663
P P +I + + EFDD D D P +G
Sbjct: 206 PSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEEG 238
>gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens]
Length = 1660
Score = 42.0 bits (97), Expect = 0.003
Identities = 49/245 (20%), Positives = 92/245 (37%), Gaps = 19/245 (7%)
Query: 817 PQKFSPEGDLCSSPD-----PKICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAA 871
P+ F+ GD+ S D C C+ S SS S++LH + H KE +A C+
Sbjct: 996 PEDFAQPGDVYSQRDVTGTGENKCLHCEFSAHSSASLELHVKRKHTKEFEFYCMA-CDYY 1054
Query: 872 FPSRRSRDRHSANINLHRKLLTKELDDMGLDSSQPSLSKDLRDEFLVKIYGAQHPMGLDV 931
+RR RH+A H+ L+ +++ +SK+ + + +H +
Sbjct: 1055 AVTRREMTRHAAT-EKHKMKRQSYLNSANVEAGSADMSKN------IIMPEEEHQQNSEE 1107
Query: 932 REDASSPAGTEDSHLNGYGRGMAEDYMVLDLSTTSSLQSSSSIHSSRESDAGSDEGILLD 991
+ S N + + LD+S S + + ES+ D +
Sbjct: 1108 FQIISGQPSDTLKSRNAADCSILNENTNLDMSKVLCAADSVEVETEEESNFNEDHS-FCE 1166
Query: 992 DIDGASDSGESAHKAEAPALPGSLGAEVSGSLMFSSLSGSNGGIMCNIC---HKMYSNKG 1048
A + E +L ++ + F + + + + C H++ ++ G
Sbjct: 1167 TFQQAPVKDKVRKPEEMMSL--TMSSNYGSPSRFQNENSGSSALNCETAKKNHEISNDAG 1224
Query: 1049 TLRVH 1053
LRVH
Sbjct: 1225 ELRVH 1229
Score = 34.3 bits (77), Expect = 0.67
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 9/92 (9%)
Query: 1001 ESAHKAEAPALPGSLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLR 1060
+ A + + A P G SL SGS C C ++ +N+ L +H K H R
Sbjct: 497 QEAEQGQGSARPPDSGLH---SLTVKPASGSQTLCACTDCGQVATNRTDLEIHVKRCHAR 553
Query: 1061 EMHKCKVPGCNMMFSSVRSRNRHSQNPNLHKN 1092
EM K C+ FSS+ +R + +LH N
Sbjct: 554 EM-KFYCRTCD--FSSM---SRRDLDEHLHSN 579
>gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens]
Length = 1815
Score = 42.0 bits (97), Expect = 0.003
Identities = 49/245 (20%), Positives = 92/245 (37%), Gaps = 19/245 (7%)
Query: 817 PQKFSPEGDLCSSPD-----PKICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAA 871
P+ F+ GD+ S D C C+ S SS S++LH + H KE +A C+
Sbjct: 996 PEDFAQPGDVYSQRDVTGTGENKCLHCEFSAHSSASLELHVKRKHTKEFEFYCMA-CDYY 1054
Query: 872 FPSRRSRDRHSANINLHRKLLTKELDDMGLDSSQPSLSKDLRDEFLVKIYGAQHPMGLDV 931
+RR RH+A H+ L+ +++ +SK+ + + +H +
Sbjct: 1055 AVTRREMTRHAAT-EKHKMKRQSYLNSANVEAGSADMSKN------IIMPEEEHQQNSEE 1107
Query: 932 REDASSPAGTEDSHLNGYGRGMAEDYMVLDLSTTSSLQSSSSIHSSRESDAGSDEGILLD 991
+ S N + + LD+S S + + ES+ D +
Sbjct: 1108 FQIISGQPSDTLKSRNAADCSILNENTNLDMSKVLCAADSVEVETEEESNFNEDHS-FCE 1166
Query: 992 DIDGASDSGESAHKAEAPALPGSLGAEVSGSLMFSSLSGSNGGIMCNIC---HKMYSNKG 1048
A + E +L ++ + F + + + + C H++ ++ G
Sbjct: 1167 TFQQAPVKDKVRKPEEMMSL--TMSSNYGSPSRFQNENSGSSALNCETAKKNHEISNDAG 1224
Query: 1049 TLRVH 1053
LRVH
Sbjct: 1225 ELRVH 1229
Score = 34.3 bits (77), Expect = 0.67
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 9/92 (9%)
Query: 1001 ESAHKAEAPALPGSLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLR 1060
+ A + + A P G SL SGS C C ++ +N+ L +H K H R
Sbjct: 497 QEAEQGQGSARPPDSGLH---SLTVKPASGSQTLCACTDCGQVATNRTDLEIHVKRCHAR 553
Query: 1061 EMHKCKVPGCNMMFSSVRSRNRHSQNPNLHKN 1092
EM K C+ FSS+ +R + +LH N
Sbjct: 554 EM-KFYCRTCD--FSSM---SRRDLDEHLHSN 579
>gi|148539870 histone deacetylase 7 isoform d [Homo sapiens]
Length = 954
Score = 42.0 bits (97), Expect = 0.003
Identities = 57/205 (27%), Positives = 82/205 (40%), Gaps = 30/205 (14%)
Query: 491 ANPNPRLH--MPMLRNNRDKDL-IRATSGAATPVIASTKSNLALTSPGRPPMGFTTPP-L 546
++PN H P+L + D D T G P++ S + L L P G T P L
Sbjct: 249 SSPNDSEHGPNPILGSEADSDRRTHPTLGPRGPILGSPHTPLFLPHGLEPEAGGTLPSRL 308
Query: 547 DPVLQ-NPLPSQLVFSGLKTVQPVP-PFYRSLLTP----GEMVSPPTSLPTSPIIPTSGT 600
P+L +P S + + P+P F +SL+T G + P S S +P S T
Sbjct: 309 QPILLLDPSGSHAPLLTVPGLGPLPFHFAQSLMTTERLSGSGLHWPLSRTRSEPLPPSAT 368
Query: 601 IEQHPPPPSEPVVPAV-MMATHEP--SADLAPKKKPRKSSMPVKIEKEIIDTADEFDDED 657
PPP P+ P + + TH P +KPR +P +D +
Sbjct: 369 A----PPPPGPMQPRLEQLKTHVQVIKRSAKPSEKPRLRQIP------------SAEDLE 412
Query: 658 DDPNDGGAVVND-MSHDNHCHSQEE 681
D G VV+D + H H Q E
Sbjct: 413 TDGGGPGQVVDDGLEHRELGHGQPE 437
>gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo
sapiens]
Length = 1048
Score = 42.0 bits (97), Expect = 0.003
Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 26/153 (16%)
Query: 510 LIRATSGAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTV--Q 567
+I A S + P +A + T PG P+ TPP+ + P PS V L +V
Sbjct: 727 MIAAASPPSQPAVALS------TIPGAVPI---TPPITTIAAAPPPSVTVGGSLSSVLGP 777
Query: 568 PVPPF-YRSLLTPGEMVSPPTSLP---TSPIIPTSGTIEQHPPPPSEPVVPAVMMATHEP 623
PVP + + P +++ P +++P T+ + P+ + + P+ + P
Sbjct: 778 PVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGA------- 830
Query: 624 SADLAPKKKPRKSSMPVKIEKEIIDTADEFDDE 656
+P+KKPRK + E+ + + DDE
Sbjct: 831 ----SPRKKPRKQQHVISTEEGDMMETNSTDDE 859
Score = 30.4 bits (67), Expect = 9.6
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 11/87 (12%)
Query: 547 DPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGTIEQHPP 606
+PV+ P P + S V TP + +PP L +P +P S + P
Sbjct: 94 EPVVVRPYPQVQMLSTHHAVASA--------TPVAVTAPPAHL--TPAVPLSFSEGLMKP 143
Query: 607 PPSEPVVPAVMMATHEPSADLAPKKKP 633
PP +P +P+ +A PS P K P
Sbjct: 144 PP-KPTMPSRPIAPAPPSTLSLPPKVP 169
>gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo
sapiens]
Length = 1083
Score = 42.0 bits (97), Expect = 0.003
Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 26/153 (16%)
Query: 510 LIRATSGAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTV--Q 567
+I A S + P +A + T PG P+ TPP+ + P PS V L +V
Sbjct: 762 MIAAASPPSQPAVALS------TIPGAVPI---TPPITTIAAAPPPSVTVGGSLSSVLGP 812
Query: 568 PVPPF-YRSLLTPGEMVSPPTSLP---TSPIIPTSGTIEQHPPPPSEPVVPAVMMATHEP 623
PVP + + P +++ P +++P T+ + P+ + + P+ + P
Sbjct: 813 PVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGA------- 865
Query: 624 SADLAPKKKPRKSSMPVKIEKEIIDTADEFDDE 656
+P+KKPRK + E+ + + DDE
Sbjct: 866 ----SPRKKPRKQQHVISTEEGDMMETNSTDDE 894
Score = 30.4 bits (67), Expect = 9.6
Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 11/87 (12%)
Query: 547 DPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGTIEQHPP 606
+PV+ P P + S V TP + +PP L +P +P S + P
Sbjct: 94 EPVVVRPYPQVQMLSTHHAVASA--------TPVAVTAPPAHL--TPAVPLSFSEGLMKP 143
Query: 607 PPSEPVVPAVMMATHEPSADLAPKKKP 633
PP +P +P+ +A PS P K P
Sbjct: 144 PP-KPTMPSRPIAPAPPSTLSLPPKVP 169
>gi|189217876 sal-like 1 isoform b [Homo sapiens]
Length = 1227
Score = 42.0 bits (97), Expect = 0.003
Identities = 65/274 (23%), Positives = 108/274 (39%), Gaps = 32/274 (11%)
Query: 643 EKEIIDTADEFDDED-DDPNDGGAVVNDMSHDNHCHSQEEMSPGMSVKDFSK----HNRT 697
+++ D D F DE+ +D +G S D SQ+ +S + S N+
Sbjct: 717 DEKNFDDLDNFSDENMEDCPEGSIPDTPKSADA---SQDSLSSSPLPLEMSSIAALENQM 773
Query: 698 RCISR--TEIRRADSMTSEDQEPERDY-ENESESSEPKLGEESMEGDEHIHSEVSEKVLM 754
+ I+ E +A + E+ E D N+S S + +S S S + L
Sbjct: 774 KMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDMESQSAGSPAISESTSSMQALS 833
Query: 755 NSERPDENHSEPSHQDVIKVKEEFTDPTYDMFYMSQYGLYNGGGASMAALH-ESFTSSLN 813
S E H PS I+ K + P+ +S + NGG + + H E +
Sbjct: 834 PSNSTQEFHKSPS----IEEKPQRAVPSEFANGLSPTPV-NGGALDLTSSHAEKIIKEDS 888
Query: 814 YGSPQKFSPEGDLCSSPDPKICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFP 873
G F G ++ C +C K+F ++ +HYR+ + +CTV CN F
Sbjct: 889 LGILFPFRDRGKFKNTA----CDICGKTFACQSALDIHYRSHTKERPFICTV--CNRGF- 941
Query: 874 SRRSRDRHSANINLHRKLLTKELDDMGLDSSQPS 907
S NL + +LT ++ D+ +PS
Sbjct: 942 --------STKGNLKQHMLTHQMRDLPSQLFEPS 967
Score = 36.6 bits (83), Expect = 0.13
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 17/84 (20%)
Query: 421 KSSFRIHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVH-----LKIKHRCTIEG 475
+S+ ++H G K C CG+ F KG LK HY +VH L+++H C I
Sbjct: 621 QSALKMHYRTHTGERPFK----CKICGRAFTTKGNLKTHY-SVHRAMPPLRVQHSCPI-- 673
Query: 476 CNMVFSSLRSRNRHSANPNPRLHM 499
C F++ +H R+HM
Sbjct: 674 CQKKFTNAVVLQQHI-----RMHM 692
Score = 35.0 bits (79), Expect = 0.39
Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 16/116 (13%)
Query: 365 ESSESEVSPTPYKNDQTP--NRNALTSITNVEPKTEPACVSPIQNSAPVSDL-------- 414
++S + V P+P N T + N+L+++ + K++P V+ + + +
Sbjct: 298 QASANSVFPSPLPNIGTTAEDLNSLSALAQ-QRKSKPPNVTAFEAKSTSDEAFFKHKCRF 356
Query: 415 -TKTEHPKSSFRIHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKH 469
K S+ +IH G K CN CG F KG LK+H+ K H
Sbjct: 357 CAKVFGSDSALQIHLRSHTGERPFK----CNICGNRFSTKGNLKVHFQRHKEKYPH 408
Score = 34.7 bits (78), Expect = 0.51
Identities = 32/133 (24%), Positives = 49/133 (36%), Gaps = 20/133 (15%)
Query: 443 CNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRH------------- 489
C+ CGKTF + L IHY + + CT+ CN FS+ + +H
Sbjct: 906 CDICGKTFACQSALDIHYRSHTKERPFICTV--CNRGFSTKGNLKQHMLTHQMRDLPSQL 963
Query: 490 ---SANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLALTSPGRPPM--GFTTP 544
S+N P + ++ N LI+ V + + P+ T+P
Sbjct: 964 FEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDTPTSHVPSGPLSSSATSP 1023
Query: 545 PLDPVLQNPLPSQ 557
L P L P Q
Sbjct: 1024 VLLPALPRRTPKQ 1036
Score = 33.9 bits (76), Expect = 0.87
Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 12/110 (10%)
Query: 963 STTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESAHKAEAPALPGSLGAEVSGS 1022
+T L S S++ R+S + + + S S E+ K + G++ +
Sbjct: 314 TTAEDLNSLSALAQQRKSKPPN-----VTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQ 368
Query: 1023 LMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNM 1072
+ S +G CNIC +S KG L+VH+ + HK K P M
Sbjct: 369 IHLRSHTGERP-FKCNICGNRFSTKGNLKVHF------QRHKEKYPHIQM 411
Score = 33.9 bits (76), Expect = 0.87
Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
Query: 1037 CNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSRNRHSQNPNLHKNIP 1094
C ICH++ S + L++HY+T KCK+ C F++ + H ++H+ +P
Sbjct: 611 CIICHRVLSCQSALKMHYRTHTGERPFKCKI--CGRAFTTKGNLKTHY---SVHRAMP 663
Score = 31.6 bits (70), Expect = 4.3
Identities = 38/158 (24%), Positives = 55/158 (34%), Gaps = 17/158 (10%)
Query: 323 LPFQYINPVSAPLLGLPPNGLLLEQPGLRLREPSLSTQNEYNESSESEVSPTPYKNDQTP 382
LP Q P S L PN P L + N + S + TP P
Sbjct: 959 LPSQLFEPSS----NLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDTP--TSHVP 1012
Query: 383 NRNALTSITNVEPKTEPACVSPIQNSAPVSDLTKTEHPKSSFRIHRMRRMGSASRKGRVF 442
+ +S T+ P PA + KT S+ +IH G
Sbjct: 1013 SGPLSSSATS--PVLLPALPRRTPKQHYCNTCGKTFSSSSALQIHERTHTGEKP----FA 1066
Query: 443 CNACGKTFYDKGTLKIH-----YNAVHLKIKHRCTIEG 475
C CG+ F KG LK+H +N+ + R +++G
Sbjct: 1067 CTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDG 1104
Score = 31.2 bits (69), Expect = 5.6
Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 2/41 (4%)
Query: 442 FCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSS 482
+CN CGKTF L+IH + CTI C F++
Sbjct: 1038 YCNTCGKTFSSSSALQIHERTHTGEKPFACTI--CGRAFTT 1076
Score = 30.8 bits (68), Expect = 7.4
Identities = 95/502 (18%), Positives = 172/502 (34%), Gaps = 68/502 (13%)
Query: 178 GTQAVPVRLKILLDRL----FSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRW 233
GT A+ L L D FSV+ ++ L + + + A+G L
Sbjct: 71 GTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEARCGGASGGKLAVP 130
Query: 234 AIMSREEEIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTFIESNNRTR 293
A+M E+++ LQQ + I +L I++ Q + + S D +
Sbjct: 131 ALM---EQLLALQQ-------QQIHQLQLIEQIRHQILLLASQNADLPTSSSPSQGTLRT 180
Query: 294 SPS----LLAHLENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLG-----LPPNGLL 344
S + L +HL ++ +++ + A + + + P+ P +P N
Sbjct: 181 SANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNTIIPSNSG- 239
Query: 345 LEQPGLRLREPSLSTQNEYNESSESEVSPTPYKNDQTPNRNALTSITNVEPKTEPACVSP 404
P + + +++T + +S + S + + A + + P + P + P
Sbjct: 240 -SSPNMNILAAAVTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPASNP--LLP 296
Query: 405 IQNSA------PVSDLTKTEHPKSSFRIHRMRRMG---------SASRKGRVF----CNA 445
Q SA P+ ++ T +S +R + S F C
Sbjct: 297 QQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRF 356
Query: 446 CGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFS---SLRSRNRHSANPNPRLHMPML 502
C K F L+IH + + +C I C FS +L+ + P + M
Sbjct: 357 CAKVFGSDSALQIHLRSHTGERPFKCNI--CGNRFSTKGNLKVHFQRHKEKYPHIQMNPY 414
Query: 503 RNNRDKDLIRATSGAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSG 562
D I ++G + + + +P + T + L LPS + F
Sbjct: 415 PVPEHLDNIPTSTGIPYGMSIPPEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLIPF-- 472
Query: 563 LKTVQPVP-PFYRSLLTPGEMVSPPTSLPTS--------------PIIPTSGTIEQHPPP 607
+KT +P P P S +P V + P S +P SG +
Sbjct: 473 IKTEEPAPIPISHSATSPPGSVKSDSGGPESATRNLGGLPEEAEGSTLPPSGGKSEESGM 532
Query: 608 PSEPVVPAVMMATHEPSADLAP 629
+ V A P+AD P
Sbjct: 533 VTNSVPTASSSVLSSPAADCGP 554
Score = 30.8 bits (68), Expect = 7.4
Identities = 21/80 (26%), Positives = 33/80 (41%), Gaps = 16/80 (20%)
Query: 816 SPQKFSPEGDLCSS--------------PDPKICYVCKKSFKSSYSVKLHYRNVHLKEMH 861
+P P G L SS P C C K+F SS ++++H R ++
Sbjct: 1006 TPTSHVPSGPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIHERTHTGEKPF 1065
Query: 862 VCTVAGCNAAFPSRRSRDRH 881
CT+ C AF ++ + H
Sbjct: 1066 ACTI--CGRAFTTKGNLKVH 1083
>gi|118442837 sal-like 1 isoform a [Homo sapiens]
Length = 1324
Score = 42.0 bits (97), Expect = 0.003
Identities = 65/274 (23%), Positives = 108/274 (39%), Gaps = 32/274 (11%)
Query: 643 EKEIIDTADEFDDED-DDPNDGGAVVNDMSHDNHCHSQEEMSPGMSVKDFSK----HNRT 697
+++ D D F DE+ +D +G S D SQ+ +S + S N+
Sbjct: 814 DEKNFDDLDNFSDENMEDCPEGSIPDTPKSADA---SQDSLSSSPLPLEMSSIAALENQM 870
Query: 698 RCISR--TEIRRADSMTSEDQEPERDY-ENESESSEPKLGEESMEGDEHIHSEVSEKVLM 754
+ I+ E +A + E+ E D N+S S + +S S S + L
Sbjct: 871 KMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDMESQSAGSPAISESTSSMQALS 930
Query: 755 NSERPDENHSEPSHQDVIKVKEEFTDPTYDMFYMSQYGLYNGGGASMAALH-ESFTSSLN 813
S E H PS I+ K + P+ +S + NGG + + H E +
Sbjct: 931 PSNSTQEFHKSPS----IEEKPQRAVPSEFANGLSPTPV-NGGALDLTSSHAEKIIKEDS 985
Query: 814 YGSPQKFSPEGDLCSSPDPKICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFP 873
G F G ++ C +C K+F ++ +HYR+ + +CTV CN F
Sbjct: 986 LGILFPFRDRGKFKNTA----CDICGKTFACQSALDIHYRSHTKERPFICTV--CNRGF- 1038
Query: 874 SRRSRDRHSANINLHRKLLTKELDDMGLDSSQPS 907
S NL + +LT ++ D+ +PS
Sbjct: 1039 --------STKGNLKQHMLTHQMRDLPSQLFEPS 1064
Score = 36.6 bits (83), Expect = 0.13
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 17/84 (20%)
Query: 421 KSSFRIHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVH-----LKIKHRCTIEG 475
+S+ ++H G K C CG+ F KG LK HY +VH L+++H C I
Sbjct: 718 QSALKMHYRTHTGERPFK----CKICGRAFTTKGNLKTHY-SVHRAMPPLRVQHSCPI-- 770
Query: 476 CNMVFSSLRSRNRHSANPNPRLHM 499
C F++ +H R+HM
Sbjct: 771 CQKKFTNAVVLQQHI-----RMHM 789
Score = 35.0 bits (79), Expect = 0.39
Identities = 29/116 (25%), Positives = 49/116 (42%), Gaps = 16/116 (13%)
Query: 365 ESSESEVSPTPYKNDQTP--NRNALTSITNVEPKTEPACVSPIQNSAPVSDL-------- 414
++S + V P+P N T + N+L+++ + K++P V+ + + +
Sbjct: 395 QASANSVFPSPLPNIGTTAEDLNSLSALAQ-QRKSKPPNVTAFEAKSTSDEAFFKHKCRF 453
Query: 415 -TKTEHPKSSFRIHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKH 469
K S+ +IH G K CN CG F KG LK+H+ K H
Sbjct: 454 CAKVFGSDSALQIHLRSHTGERPFK----CNICGNRFSTKGNLKVHFQRHKEKYPH 505
Score = 34.7 bits (78), Expect = 0.51
Identities = 32/133 (24%), Positives = 49/133 (36%), Gaps = 20/133 (15%)
Query: 443 CNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRH------------- 489
C+ CGKTF + L IHY + + CT+ CN FS+ + +H
Sbjct: 1003 CDICGKTFACQSALDIHYRSHTKERPFICTV--CNRGFSTKGNLKQHMLTHQMRDLPSQL 1060
Query: 490 ---SANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLALTSPGRPPM--GFTTP 544
S+N P + ++ N LI+ V + + P+ T+P
Sbjct: 1061 FEPSSNLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDTPTSHVPSGPLSSSATSP 1120
Query: 545 PLDPVLQNPLPSQ 557
L P L P Q
Sbjct: 1121 VLLPALPRRTPKQ 1133
Score = 33.9 bits (76), Expect = 0.87
Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 12/110 (10%)
Query: 963 STTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESAHKAEAPALPGSLGAEVSGS 1022
+T L S S++ R+S + + + S S E+ K + G++ +
Sbjct: 411 TTAEDLNSLSALAQQRKSKPPN-----VTAFEAKSTSDEAFFKHKCRFCAKVFGSDSALQ 465
Query: 1023 LMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNM 1072
+ S +G CNIC +S KG L+VH+ + HK K P M
Sbjct: 466 IHLRSHTGERP-FKCNICGNRFSTKGNLKVHF------QRHKEKYPHIQM 508
Score = 33.9 bits (76), Expect = 0.87
Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
Query: 1037 CNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSRNRHSQNPNLHKNIP 1094
C ICH++ S + L++HY+T KCK+ C F++ + H ++H+ +P
Sbjct: 708 CIICHRVLSCQSALKMHYRTHTGERPFKCKI--CGRAFTTKGNLKTHY---SVHRAMP 760
Score = 31.6 bits (70), Expect = 4.3
Identities = 38/158 (24%), Positives = 55/158 (34%), Gaps = 17/158 (10%)
Query: 323 LPFQYINPVSAPLLGLPPNGLLLEQPGLRLREPSLSTQNEYNESSESEVSPTPYKNDQTP 382
LP Q P S L PN P L + N + S + TP P
Sbjct: 1056 LPSQLFEPSS----NLGPNQNSAVIPANSLSSLIKTEVNGFVHVSPQDSKDTP--TSHVP 1109
Query: 383 NRNALTSITNVEPKTEPACVSPIQNSAPVSDLTKTEHPKSSFRIHRMRRMGSASRKGRVF 442
+ +S T+ P PA + KT S+ +IH G
Sbjct: 1110 SGPLSSSATS--PVLLPALPRRTPKQHYCNTCGKTFSSSSALQIHERTHTGEKP----FA 1163
Query: 443 CNACGKTFYDKGTLKIH-----YNAVHLKIKHRCTIEG 475
C CG+ F KG LK+H +N+ + R +++G
Sbjct: 1164 CTICGRAFTTKGNLKVHMGTHMWNSTPARRGRRLSVDG 1201
Score = 31.2 bits (69), Expect = 5.6
Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 2/41 (4%)
Query: 442 FCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSS 482
+CN CGKTF L+IH + CTI C F++
Sbjct: 1135 YCNTCGKTFSSSSALQIHERTHTGEKPFACTI--CGRAFTT 1173
Score = 30.8 bits (68), Expect = 7.4
Identities = 95/502 (18%), Positives = 172/502 (34%), Gaps = 68/502 (13%)
Query: 178 GTQAVPVRLKILLDRL----FSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRW 233
GT A+ L L D FSV+ ++ L + + + A+G L
Sbjct: 168 GTSAITTSLPQLGDLTTLGNFSVINSNVIIENLQSTKVAVAQFSQEARCGGASGGKLAVP 227
Query: 234 AIMSREEEIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTFIESNNRTR 293
A+M E+++ LQQ + I +L I++ Q + + S D +
Sbjct: 228 ALM---EQLLALQQ-------QQIHQLQLIEQIRHQILLLASQNADLPTSSSPSQGTLRT 277
Query: 294 SPS----LLAHLENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLG-----LPPNGLL 344
S + L +HL ++ +++ + A + + + P+ P +P N
Sbjct: 278 SANPLSTLSSHLSQQLAAAAGLAQSLASQSASISGVKQLPPIQLPQSSSGNTIIPSNSG- 336
Query: 345 LEQPGLRLREPSLSTQNEYNESSESEVSPTPYKNDQTPNRNALTSITNVEPKTEPACVSP 404
P + + +++T + +S + S + + A + + P + P + P
Sbjct: 337 -SSPNMNILAAAVTTPSSEKVASSAGASHVSNPAVSSSSSPAFAISSLLSPASNP--LLP 393
Query: 405 IQNSA------PVSDLTKTEHPKSSFRIHRMRRMG---------SASRKGRVF----CNA 445
Q SA P+ ++ T +S +R + S F C
Sbjct: 394 QQASANSVFPSPLPNIGTTAEDLNSLSALAQQRKSKPPNVTAFEAKSTSDEAFFKHKCRF 453
Query: 446 CGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFS---SLRSRNRHSANPNPRLHMPML 502
C K F L+IH + + +C I C FS +L+ + P + M
Sbjct: 454 CAKVFGSDSALQIHLRSHTGERPFKCNI--CGNRFSTKGNLKVHFQRHKEKYPHIQMNPY 511
Query: 503 RNNRDKDLIRATSGAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSG 562
D I ++G + + + +P + T + L LPS + F
Sbjct: 512 PVPEHLDNIPTSTGIPYGMSIPPEKPVTSWLDTKPVLPTLTTSVGLPLPPTLPSLIPF-- 569
Query: 563 LKTVQPVP-PFYRSLLTPGEMVSPPTSLPTS--------------PIIPTSGTIEQHPPP 607
+KT +P P P S +P V + P S +P SG +
Sbjct: 570 IKTEEPAPIPISHSATSPPGSVKSDSGGPESATRNLGGLPEEAEGSTLPPSGGKSEESGM 629
Query: 608 PSEPVVPAVMMATHEPSADLAP 629
+ V A P+AD P
Sbjct: 630 VTNSVPTASSSVLSSPAADCGP 651
Score = 30.8 bits (68), Expect = 7.4
Identities = 21/80 (26%), Positives = 33/80 (41%), Gaps = 16/80 (20%)
Query: 816 SPQKFSPEGDLCSS--------------PDPKICYVCKKSFKSSYSVKLHYRNVHLKEMH 861
+P P G L SS P C C K+F SS ++++H R ++
Sbjct: 1103 TPTSHVPSGPLSSSATSPVLLPALPRRTPKQHYCNTCGKTFSSSSALQIHERTHTGEKPF 1162
Query: 862 VCTVAGCNAAFPSRRSRDRH 881
CT+ C AF ++ + H
Sbjct: 1163 ACTI--CGRAFTTKGNLKVH 1180
>gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens]
Length = 2248
Score = 42.0 bits (97), Expect = 0.003
Identities = 49/245 (20%), Positives = 92/245 (37%), Gaps = 19/245 (7%)
Query: 817 PQKFSPEGDLCSSPD-----PKICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAA 871
P+ F+ GD+ S D C C+ S SS S++LH + H KE +A C+
Sbjct: 996 PEDFAQPGDVYSQRDVTGTGENKCLHCEFSAHSSASLELHVKRKHTKEFEFYCMA-CDYY 1054
Query: 872 FPSRRSRDRHSANINLHRKLLTKELDDMGLDSSQPSLSKDLRDEFLVKIYGAQHPMGLDV 931
+RR RH+A H+ L+ +++ +SK+ + + +H +
Sbjct: 1055 AVTRREMTRHAAT-EKHKMKRQSYLNSANVEAGSADMSKN------IIMPEEEHQQNSEE 1107
Query: 932 REDASSPAGTEDSHLNGYGRGMAEDYMVLDLSTTSSLQSSSSIHSSRESDAGSDEGILLD 991
+ S N + + LD+S S + + ES+ D +
Sbjct: 1108 FQIISGQPSDTLKSRNAADCSILNENTNLDMSKVLCAADSVEVETEEESNFNEDHS-FCE 1166
Query: 992 DIDGASDSGESAHKAEAPALPGSLGAEVSGSLMFSSLSGSNGGIMCNIC---HKMYSNKG 1048
A + E +L ++ + F + + + + C H++ ++ G
Sbjct: 1167 TFQQAPVKDKVRKPEEMMSL--TMSSNYGSPSRFQNENSGSSALNCETAKKNHEISNDAG 1224
Query: 1049 TLRVH 1053
LRVH
Sbjct: 1225 ELRVH 1229
Score = 34.3 bits (77), Expect = 0.67
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 9/92 (9%)
Query: 1001 ESAHKAEAPALPGSLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLR 1060
+ A + + A P G SL SGS C C ++ +N+ L +H K H R
Sbjct: 497 QEAEQGQGSARPPDSGLH---SLTVKPASGSQTLCACTDCGQVATNRTDLEIHVKRCHAR 553
Query: 1061 EMHKCKVPGCNMMFSSVRSRNRHSQNPNLHKN 1092
EM K C+ FSS+ +R + +LH N
Sbjct: 554 EM-KFYCRTCD--FSSM---SRRDLDEHLHSN 579
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 42.0 bits (97), Expect = 0.003
Identities = 61/255 (23%), Positives = 91/255 (35%), Gaps = 37/255 (14%)
Query: 532 TSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPT 591
+SP +PP G T P P P+ +GL V P PPF + PG PP + PT
Sbjct: 445 SSPAQPP-GLTQSQNLP----PPPASHPPTGLHQVAPQPPFAQHPFVPGG--PPPITPPT 497
Query: 592 SPIIPTSGTIEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMPVKIEKEIIDTAD 651
P T P P P A + P + V+I++E +D A+
Sbjct: 498 CPSTSTP------PAGPGTSAQPPCSGAAASGGSIAGGSSCPLPT---VQIKEEALDDAE 548
Query: 652 EFDDEDDDPNDGG---AVVNDMSHD--------------NHCHSQEEMSPGMSVKDFSKH 694
E + P VV+ SH N C + ++ +K
Sbjct: 549 EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAK- 607
Query: 695 NRTRCISRTEIRRADSMTSEDQEPERDYENESESSEPKLGEESMEGDEHIHSEVSEKVLM 754
R I + + R A+ E++E E++ E E E + E E S E L
Sbjct: 608 KREEAIEKAK-REAEQKAREEREREKEKEKERERERER--EREAERAAKASSSAHEGRLS 664
Query: 755 NSERPDENHSEPSHQ 769
+ + H PS +
Sbjct: 665 DPQLSGPGHMRPSFE 679
Score = 31.6 bits (70), Expect = 4.3
Identities = 41/155 (26%), Positives = 57/155 (36%), Gaps = 35/155 (22%)
Query: 516 GAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRS 575
G P S ++ L PG PP F PP Q PL + + T +P +
Sbjct: 294 GQGPPGPHSLQAGPLLQHPG-PPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSA 352
Query: 576 LLT---PGEMVSPPTSL--------PTSPI--IPTSGTIEQHPP--------------PP 608
L + P E PP L PT+PI +P +HPP PP
Sbjct: 353 LQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA-HKHPPHLSGPSPFSMNANLPP 411
Query: 609 SEPVVPAVMMATHEPSA------DLAPKKKPRKSS 637
+ P ++TH P + L P+ +P SS
Sbjct: 412 PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSS 446
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 42.0 bits (97), Expect = 0.003
Identities = 61/255 (23%), Positives = 91/255 (35%), Gaps = 37/255 (14%)
Query: 532 TSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPT 591
+SP +PP G T P P P+ +GL V P PPF + PG PP + PT
Sbjct: 999 SSPAQPP-GLTQSQNLP----PPPASHPPTGLHQVAPQPPFAQHPFVPGG--PPPITPPT 1051
Query: 592 SPIIPTSGTIEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMPVKIEKEIIDTAD 651
P T P P P A + P + V+I++E +D A+
Sbjct: 1052 CPSTSTP------PAGPGTSAQPPCSGAAASGGSIAGGSSCPLPT---VQIKEEALDDAE 1102
Query: 652 EFDDEDDDPNDGG---AVVNDMSHD--------------NHCHSQEEMSPGMSVKDFSKH 694
E + P VV+ SH N C + ++ +K
Sbjct: 1103 EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAK- 1161
Query: 695 NRTRCISRTEIRRADSMTSEDQEPERDYENESESSEPKLGEESMEGDEHIHSEVSEKVLM 754
R I + + R A+ E++E E++ E E E + E E S E L
Sbjct: 1162 KREEAIEKAK-REAEQKAREEREREKEKEKERERERER--EREAERAAKASSSAHEGRLS 1218
Query: 755 NSERPDENHSEPSHQ 769
+ + H PS +
Sbjct: 1219 DPQLSGPGHMRPSFE 1233
Score = 31.6 bits (70), Expect = 4.3
Identities = 41/155 (26%), Positives = 57/155 (36%), Gaps = 35/155 (22%)
Query: 516 GAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRS 575
G P S ++ L PG PP F PP Q PL + + T +P +
Sbjct: 848 GQGPPGPHSLQAGPLLQHPG-PPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSA 906
Query: 576 LLT---PGEMVSPPTSL--------PTSPI--IPTSGTIEQHPP--------------PP 608
L + P E PP L PT+PI +P +HPP PP
Sbjct: 907 LQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA-HKHPPHLSGPSPFSMNANLPP 965
Query: 609 SEPVVPAVMMATHEPSA------DLAPKKKPRKSS 637
+ P ++TH P + L P+ +P SS
Sbjct: 966 PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSS 1000
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 42.0 bits (97), Expect = 0.003
Identities = 61/255 (23%), Positives = 91/255 (35%), Gaps = 37/255 (14%)
Query: 532 TSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPT 591
+SP +PP G T P P P+ +GL V P PPF + PG PP + PT
Sbjct: 999 SSPAQPP-GLTQSQNLP----PPPASHPPTGLHQVAPQPPFAQHPFVPGG--PPPITPPT 1051
Query: 592 SPIIPTSGTIEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMPVKIEKEIIDTAD 651
P T P P P A + P + V+I++E +D A+
Sbjct: 1052 CPSTSTP------PAGPGTSAQPPCSGAAASGGSIAGGSSCPLPT---VQIKEEALDDAE 1102
Query: 652 EFDDEDDDPNDGG---AVVNDMSHD--------------NHCHSQEEMSPGMSVKDFSKH 694
E + P VV+ SH N C + ++ +K
Sbjct: 1103 EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAK- 1161
Query: 695 NRTRCISRTEIRRADSMTSEDQEPERDYENESESSEPKLGEESMEGDEHIHSEVSEKVLM 754
R I + + R A+ E++E E++ E E E + E E S E L
Sbjct: 1162 KREEAIEKAK-REAEQKAREEREREKEKEKERERERER--EREAERAAKASSSAHEGRLS 1218
Query: 755 NSERPDENHSEPSHQ 769
+ + H PS +
Sbjct: 1219 DPQLSGPGHMRPSFE 1233
Score = 31.6 bits (70), Expect = 4.3
Identities = 41/155 (26%), Positives = 57/155 (36%), Gaps = 35/155 (22%)
Query: 516 GAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRS 575
G P S ++ L PG PP F PP Q PL + + T +P +
Sbjct: 848 GQGPPGPHSLQAGPLLQHPG-PPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSA 906
Query: 576 LLT---PGEMVSPPTSL--------PTSPI--IPTSGTIEQHPP--------------PP 608
L + P E PP L PT+PI +P +HPP PP
Sbjct: 907 LQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA-HKHPPHLSGPSPFSMNANLPP 965
Query: 609 SEPVVPAVMMATHEPSA------DLAPKKKPRKSS 637
+ P ++TH P + L P+ +P SS
Sbjct: 966 PPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSS 1000
>gi|46359075 zinc finger protein 423 [Homo sapiens]
Length = 1284
Score = 41.6 bits (96), Expect = 0.004
Identities = 64/252 (25%), Positives = 91/252 (36%), Gaps = 59/252 (23%)
Query: 832 PKICYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINLH--- 888
P C C KSF +K H + K CT C+ F +RSRDRH I LH
Sbjct: 137 PYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTY--CSRLFKHKRSRDRH---IKLHTGD 191
Query: 889 RKLLTKELDDMGLDSSQPSLSKDLRDEFLVKIYGAQHPMGLDVREDASSPAGTEDSHLNG 948
+K E + + S+ + +K + + P V +
Sbjct: 192 KKYHCHECE--------AAFSRSDHLKIHLKTHSSSKPFKCTVCK--------------- 228
Query: 949 YGRGMAEDYMVLDLSTTSSLQSSSSIHS-SRESDAGSDEGILLDDI--DGASDSGESAHK 1005
RG S+TSSLQS H ++E A S++ DD D D+ +
Sbjct: 229 --RGF---------SSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEE 277
Query: 1006 AEAPALPGSLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKC 1065
E L LS + C C +++ ++ TL H H + HKC
Sbjct: 278 LEKHVLT-----------RHPQLS-EKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKC 325
Query: 1066 KVPGCNMMFSSV 1077
P C FSSV
Sbjct: 326 --PMCPEQFSSV 335
Score = 40.0 bits (92), Expect = 0.012
Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 10/104 (9%)
Query: 427 HRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKHRC--------TIEG--C 476
H + R S K + C C + F D+ TL H + H KH+C ++EG C
Sbjct: 281 HVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYC 340
Query: 477 NMVFSSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATP 520
++ + HS +P+P L ++ D + +TP
Sbjct: 341 HLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTP 384
Score = 38.5 bits (88), Expect = 0.035
Identities = 56/259 (21%), Positives = 93/259 (35%), Gaps = 13/259 (5%)
Query: 835 CYVCKKSFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINL------H 888
C +C++ F S S+++H H E + CN F H + +L H
Sbjct: 722 CTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAH 781
Query: 889 RKLLTKEL--DDMGLDSSQPSLSKDLRDEFLVKIYGAQHPMGLDVRE-DASSPAGTEDSH 945
+ + E ++ L + SK +F K + A + +RE A TE+
Sbjct: 782 KCIFCGETFSTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGT 841
Query: 946 LNGYGRGMAEDYMVLDL-STTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESAH 1004
NG + DL + + H + E D + E + DI GA+ + E
Sbjct: 842 ANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLL 901
Query: 1005 KAEAPALPGSLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHK 1064
+ E GS + G CN+C + + ++ LR H +T H
Sbjct: 902 QNHRLRDHNIRPGEDDGSRKKAEF--IKGSHKCNVCSRTFFSENGLREHLQT-HRGPAKH 958
Query: 1065 CKVPGCNMMFSSVRSRNRH 1083
P C F S+ + H
Sbjct: 959 YMCPICGERFPSLLTLTEH 977
Score = 33.5 bits (75), Expect = 1.1
Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 1005 KAEAPALPGSLGAEVSGS----LMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLR 1060
K++A P S EVS L S+ S SNG CN C +SN + + H K +HL
Sbjct: 598 KSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLK-LHLE 656
Query: 1061 -EMHKCKVPGCNMMFSSVRSRNRH 1083
+ K P C F S S +H
Sbjct: 657 LLLRKQACPQCKEDFDSQESLLQH 680
Score = 32.0 bits (71), Expect = 3.3
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 443 CNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVFSSLRSRNRH 489
C C K+F LK H K+ +CT C+ +F RSR+RH
Sbjct: 140 CQFCDKSFIRLSYLKRHEQIHSDKLPFKCTY--CSRLFKHKRSRDRH 184
Score = 31.6 bits (70), Expect = 4.3
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 1037 CNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSRNRHSQ 1085
C+ C +S L++H KT + KC V C FSS S H Q
Sbjct: 196 CHECEAAFSRSDHLKIHLKTHSSSKPFKCTV--CKRGFSSTSSLQSHMQ 242
Score = 31.6 bits (70), Expect = 4.3
Identities = 33/126 (26%), Positives = 48/126 (38%), Gaps = 9/126 (7%)
Query: 377 KNDQTPNRNALTSITNVEPKTEPACVSPIQNSAPVSDLTKTEHPKSSFRIHRMRRMGSAS 436
KN + PN + S +V+ +EP I +A ++ H I GS
Sbjct: 864 KNPEAPNSHE-ASEDDVDA-SEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRK 921
Query: 437 R----KGRVFCNACGKTFYDKGTLKIHYNAVHLKIKH-RCTIEGCNMVFSSLRSRNRHSA 491
+ KG CN C +TF+ + L+ H KH C I C F SL + H
Sbjct: 922 KAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPI--CGERFPSLLTLTEHKV 979
Query: 492 NPNPRL 497
+ L
Sbjct: 980 THSKSL 985
Score = 30.8 bits (68), Expect = 7.4
Identities = 17/63 (26%), Positives = 28/63 (44%), Gaps = 6/63 (9%)
Query: 1037 CNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFS-----SVRSRNRHSQNP-NLH 1090
C +C +++ +K +++VH H E + CN F V ++ H NP H
Sbjct: 722 CTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAH 781
Query: 1091 KNI 1093
K I
Sbjct: 782 KCI 784
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 41.6 bits (96), Expect = 0.004
Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 4/117 (3%)
Query: 651 DEFDDED--DDPNDGGAVVNDMSHDNHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRRA 708
D+ DD D DD +D V +D S D+ + ++ S D S + ++ A
Sbjct: 217 DKSDDSDVPDDSSDDSDVPDDSSDDSE--APDDSSDDSEAPDDSSDDSEAPDDSSDDSEA 274
Query: 709 DSMTSEDQEPERDYENESESSEPKLGEESMEGDEHIHSEVSEKVLMNSERPDENHSE 765
+S+D E D ++SE+S+ + D+ S+V E +S+ PD+N +
Sbjct: 275 PDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDD 331
Score = 37.7 bits (86), Expect = 0.060
Identities = 31/125 (24%), Positives = 52/125 (41%), Gaps = 4/125 (3%)
Query: 648 DTADEFDDEDDDPNDGGAVVNDMSHDNHCHSQ--EEMSPGMSVKDFSKHNRTRCISRTEI 705
D +D DD DD +D + +D S DN S ++ S V D S + ++
Sbjct: 184 DDSDVPDDNSDDSSDDNS--DDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDD 241
Query: 706 RRADSMTSEDQEPERDYENESESSEPKLGEESMEGDEHIHSEVSEKVLMNSERPDENHSE 765
A +S+D E D ++SE+ + + D SE S+ +SE D++ +
Sbjct: 242 SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDD 301
Query: 766 PSHQD 770
D
Sbjct: 302 SEAPD 306
Score = 36.6 bits (83), Expect = 0.13
Identities = 29/137 (21%), Positives = 54/137 (39%), Gaps = 13/137 (9%)
Query: 648 DTADEFDDEDDDPNDGGAVVNDMSHDNHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRR 707
+ D+ D+ D P+D +D S DN S ++ S V D +++
Sbjct: 177 EAPDDNSDDSDVPDDNS---DDSSDDNSDDSSDDNSDDSDVPD----------DKSDDSD 223
Query: 708 ADSMTSEDQEPERDYENESESSEPKLGEESMEGDEHIHSEVSEKVLMNSERPDENHSEPS 767
+S+D + D ++SE+ + + D SE + +SE PD++ +
Sbjct: 224 VPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSE 283
Query: 768 HQDVIKVKEEFTDPTYD 784
D E +D + D
Sbjct: 284 ASDDSSDDSEASDDSSD 300
Score = 34.7 bits (78), Expect = 0.51
Identities = 28/122 (22%), Positives = 49/122 (40%), Gaps = 4/122 (3%)
Query: 651 DEFDDED--DDPNDGGAVVNDMSHDNHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRRA 708
D DD D DD +D V +D S D+ ++ S D S + ++ A
Sbjct: 207 DNSDDSDVPDDKSDDSDVPDDSSDDSDV--PDDSSDDSEAPDDSSDDSEAPDDSSDDSEA 264
Query: 709 DSMTSEDQEPERDYENESESSEPKLGEESMEGDEHIHSEVSEKVLMNSERPDENHSEPSH 768
+S+D E D ++SE+S+ + D SE + +S+ P++ +
Sbjct: 265 PDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDV 324
Query: 769 QD 770
D
Sbjct: 325 PD 326
Score = 33.1 bits (74), Expect = 1.5
Identities = 34/179 (18%), Positives = 65/179 (36%), Gaps = 11/179 (6%)
Query: 603 QHPPPPSEPVVPAVMMATHEPSADLAPKKKP-RKSSMPVKIEKEIIDTADEFDDEDDDPN 661
Q P + + V ++ + S ++ P R++S + ++ DT+
Sbjct: 12 QEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKR 71
Query: 662 DGGAVVN-DMSHDNHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRRADSMTSEDQ---- 716
+VV D D CH+ EE + + + C + I+ + S+D
Sbjct: 72 QASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDD 131
Query: 717 -----EPERDYENESESSEPKLGEESMEGDEHIHSEVSEKVLMNSERPDENHSEPSHQD 770
E D ++SE+ + + D SE + +SE PD+N + D
Sbjct: 132 NGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPD 190
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 41.6 bits (96), Expect = 0.004
Identities = 47/217 (21%), Positives = 88/217 (40%), Gaps = 20/217 (9%)
Query: 561 SGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSP--IIPTSGTIEQHPPPPSEPVVPAVMM 618
+G K PP + + P E V+ TS P+ IE+ E ++P
Sbjct: 1267 TGFKLNLYTPP--ETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEEN 1324
Query: 619 ATHEPSADLAPKKKPRKSS-----MPVKIEKEIIDTADEFDDEDDDPNDGGAVVNDMSHD 673
E A ++P P + P + E+E + +E ++E+ + +GG V
Sbjct: 1325 RREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE--KDP 1382
Query: 674 NHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRRADSMTSEDQEPERDYENESESSEPKL 733
+ SQE+ P +S + K + R E ED+EP + +++++ +
Sbjct: 1383 DGAKSQEKEEPEISTE---KEDSARLDDHEEEEE------EDEEPSHNEDHDADDEDDSH 1433
Query: 734 GEESMEGDEHIHSEVSEKVLMNSERPDENHSEPSHQD 770
E + E + E ++VL N E + + +P H +
Sbjct: 1434 MESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSN 1470
Score = 35.8 bits (81), Expect = 0.23
Identities = 36/189 (19%), Positives = 71/189 (37%), Gaps = 40/189 (21%)
Query: 607 PPSEPVVPAVMMATHEPSADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDPNDGGAV 666
PP P+ P + E K P P++IE+E+ +T + ++++ +
Sbjct: 1276 PPETPMEPDEQVTVEEQKETSEGKTSPS----PIRIEEEVKETGEALLPQEENRRE---- 1327
Query: 667 VNDMSHDNHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRRADSMTSEDQEPERDYENES 726
+ SPG +D + + E + E++E E + E E
Sbjct: 1328 ------ETCAPVSPNTSPGEKPEDD--------LIKPEEEEEEEEEEEEEEEEEEGEEEE 1373
Query: 727 ---------------ESSEPKLG---EESMEGDEHIHSEVSEKVLMNSERPDENHSEPSH 768
E EP++ E+S D+H E ++ ++E D + + SH
Sbjct: 1374 GGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSH 1433
Query: 769 QDVIKVKEE 777
+ +V++E
Sbjct: 1434 MESAEVEKE 1442
>gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Homo
sapiens]
Length = 728
Score = 41.2 bits (95), Expect = 0.005
Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 22/148 (14%)
Query: 511 IRATSGAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVP 570
+R T +A PV+ + S R P G P+ P++ P + V P+P
Sbjct: 521 VRTTVVSAVPVMPRPP----MASVVRLPPGSVIAPMPPIIHAPRIN---------VVPMP 567
Query: 571 PFYRSLLTPGE--MVSPPTSLPTSPIIPTSGTIEQ---HPPPPSEPVVPAVMMATHEPSA 625
P ++ P M+ P +P P+ P HPPPP E + + T +
Sbjct: 568 PSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTED--- 624
Query: 626 DLAPKKK-PRKSSMPVKIEKEIIDTADE 652
L P+++ R++ PV I+ ++ + D+
Sbjct: 625 SLMPEEEFLRRNKGPVSIKVQVPNMQDK 652
>gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo
sapiens]
Length = 793
Score = 41.2 bits (95), Expect = 0.005
Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 22/148 (14%)
Query: 511 IRATSGAATPVIASTKSNLALTSPGRPPMGFTTPPLDPVLQNPLPSQLVFSGLKTVQPVP 570
+R T +A PV+ + S R P G P+ P++ P + V P+P
Sbjct: 586 VRTTVVSAVPVMPRPP----MASVVRLPPGSVIAPMPPIIHAPRIN---------VVPMP 632
Query: 571 PFYRSLLTPGE--MVSPPTSLPTSPIIPTSGTIEQ---HPPPPSEPVVPAVMMATHEPSA 625
P ++ P M+ P +P P+ P HPPPP E + + T +
Sbjct: 633 PSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTED--- 689
Query: 626 DLAPKKK-PRKSSMPVKIEKEIIDTADE 652
L P+++ R++ PV I+ ++ + D+
Sbjct: 690 SLMPEEEFLRRNKGPVSIKVQVPNMQDK 717
>gi|239747212 PREDICTED: hypothetical protein XP_002346939 [Homo
sapiens]
Length = 1158
Score = 40.8 bits (94), Expect = 0.007
Identities = 43/187 (22%), Positives = 73/187 (39%), Gaps = 26/187 (13%)
Query: 832 PKICYVCKKSFKSSYSVKLHYRNVHLKEM-HVCTVAGCNAAFPSRRSRDRH-------SA 883
P C C +SF S +++ H RN+H KE C + CN F + + DRH +A
Sbjct: 879 PYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHL--CNRCFGQQTNLDRHLKKHEHENA 936
Query: 884 NINLHRKLLTKELDDMGLDSSQPSLSKDLRDEFLVKIYGAQHPMGLDVREDASSPAGTED 943
++ H +LT L G +S P+ D H + LD +ED+
Sbjct: 937 PVSQHPGVLTNHL---GTSASSPTSESD------------NHAL-LDEKEDSYFSEIRNF 980
Query: 944 SHLNGYGRGMAEDYMVLDLSTTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESA 1003
+ + D+ + S ++ D ++ L++ D S +G+S
Sbjct: 981 IANSEMNQASTRTEKRADMQIVDGSAQCPGLASEKQEDVEEEDDDDLEEDDEDSLAGKSQ 1040
Query: 1004 HKAEAPA 1010
+PA
Sbjct: 1041 DDTVSPA 1047
Score = 37.7 bits (86), Expect = 0.060
Identities = 56/260 (21%), Positives = 87/260 (33%), Gaps = 54/260 (20%)
Query: 443 CNACGKTFYDKGTLKIH---------------------------YNAVHLKIKHRCTIEG 475
C CGKTF LK H + +H + + +
Sbjct: 269 CPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKD 328
Query: 476 CNMVFSSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLALTSPG 535
C +FS+ S N+H + H G P + T S + +
Sbjct: 329 CGQMFSTTSSLNKHRRFCEGKNHY-------------TPGGIFAPGLPLTPSPMMDKAKP 375
Query: 536 RPPMGFTTPPLDPVL-QNPLPSQLVFSGLKTVQPV-----PPFYRSLLTPGEMVSPPTSL 589
P + + + P P L FS P P + L P + PPT L
Sbjct: 376 SPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTFPALTPGFPGIFPPSLYPRPPLLPPTPL 435
Query: 590 PTSPIIPTSGTIEQHPPP---PSEPVVPAVMMATHEPSADLAPKKK---PRKSSMPVKIE 643
SP+ T + P P P+ P+V AV ++ +A P++K + S K++
Sbjct: 436 LKSPLNHTQDA--KLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCVEKLK 493
Query: 644 KEIIDTADEFDDEDDDPNDG 663
D +D D ED + G
Sbjct: 494 TRSSDMSDGSDFEDVNTTTG 513
Score = 37.4 bits (85), Expect = 0.079
Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 3/80 (3%)
Query: 1006 AEAPALP--GSLGAEVSGSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMH 1063
A A A P G A SG + + +C +CHK Y+ L H K +H
Sbjct: 264 ARAHACPDCGKTFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFSNLCRH-KRMHADCRT 322
Query: 1064 KCKVPGCNMMFSSVRSRNRH 1083
+ K C MFS+ S N+H
Sbjct: 323 QIKCKDCGQMFSTTSSLNKH 342
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,469,853
Number of Sequences: 37866
Number of extensions: 2486296
Number of successful extensions: 21983
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 734
Number of HSP's that attempted gapping in prelim test: 15336
Number of HSP's gapped (non-prelim): 7294
length of query: 1099
length of database: 18,247,518
effective HSP length: 113
effective length of query: 986
effective length of database: 13,968,660
effective search space: 13773098760
effective search space used: 13773098760
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.