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Search of human proteins with 93352558
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|93352558 rhomboid, veinlet-like 6 isoform 2 [Homo sapiens]
(827 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|93352558 rhomboid, veinlet-like 6 isoform 2 [Homo sapiens] 1713 0.0
gi|93352556 rhomboid, veinlet-like 6 isoform 1 [Homo sapiens] 1698 0.0
gi|190341097 rhomboid family 1 [Homo sapiens] 971 0.0
gi|54144654 rhomboid protease 2 [Homo sapiens] 55 3e-07
gi|21264326 rhomboid protease 3 [Homo sapiens] 54 8e-07
gi|4506525 rhomboid protease 1 [Homo sapiens] 43 0.001
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 38 0.044
gi|169213985 PREDICTED: similar to hCG2036794 [Homo sapiens] 36 0.17
gi|239751846 PREDICTED: similar to hCG2036794 [Homo sapiens] 36 0.17
gi|239746337 PREDICTED: similar to hCG2036794 [Homo sapiens] 36 0.17
gi|239742114 PREDICTED: similar to hCG2023245 [Homo sapiens] 33 1.1
gi|239755571 PREDICTED: hypothetical protein [Homo sapiens] 33 1.4
gi|239744417 PREDICTED: similar to hCG2023245 [Homo sapiens] 33 1.4
gi|65301141 PH domain and leucine rich repeat protein phosphatas... 32 1.8
gi|7706589 GNAS complex locus NESP55 [Homo sapiens] 32 2.4
gi|121949815 placenta-specific 4 [Homo sapiens] 32 2.4
gi|4507161 SRY-box 11 [Homo sapiens] 32 3.1
gi|148833508 notch1 preproprotein [Homo sapiens] 31 4.1
gi|13899309 ribosomal protein S6 kinase-like 1 [Homo sapiens] 31 4.1
gi|150418009 transforming, acidic coiled-coil containing protein... 31 4.1
gi|45827755 transforming, acidic coiled-coil containing protein ... 31 4.1
gi|45827753 transforming, acidic coiled-coil containing protein ... 31 4.1
gi|11119414 transforming, acidic coiled-coil containing protein ... 31 4.1
gi|223671872 inhibitor of kappa light polypeptide gene enhancer ... 31 5.4
gi|223671870 inhibitor of kappa light polypeptide gene enhancer ... 31 5.4
gi|4504631 inhibitor of kappa light polypeptide gene enhancer in... 31 5.4
gi|153792133 inhibitor of kappa light polypeptide gene enhancer ... 31 5.4
gi|33286444 mastermind-like 2 [Homo sapiens] 31 5.4
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 31 5.4
gi|73747881 zinc finger, ZZ type with EF hand domain 1 [Homo sap... 31 5.4
>gi|93352558 rhomboid, veinlet-like 6 isoform 2 [Homo sapiens]
Length = 827
Score = 1713 bits (4437), Expect = 0.0
Identities = 827/827 (100%), Positives = 827/827 (100%)
Query: 1 MASADKNGGSVSSVSSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPERKNPAYLKSV 60
MASADKNGGSVSSVSSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPERKNPAYLKSV
Sbjct: 1 MASADKNGGSVSSVSSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPERKNPAYLKSV 60
Query: 61 SLQEPRSRWQESSEKRPGFRRQASLSQSIRKGAAQWFGVSGDWEGQRQQWQRRSLHHCSM 120
SLQEPRSRWQESSEKRPGFRRQASLSQSIRKGAAQWFGVSGDWEGQRQQWQRRSLHHCSM
Sbjct: 61 SLQEPRSRWQESSEKRPGFRRQASLSQSIRKGAAQWFGVSGDWEGQRQQWQRRSLHHCSM 120
Query: 121 RYGRLKASCQRDLELPSQEAPSFQGTESPKPCKMPKIVDPLARGRAFRHPEEMDRPHAPH 180
RYGRLKASCQRDLELPSQEAPSFQGTESPKPCKMPKIVDPLARGRAFRHPEEMDRPHAPH
Sbjct: 121 RYGRLKASCQRDLELPSQEAPSFQGTESPKPCKMPKIVDPLARGRAFRHPEEMDRPHAPH 180
Query: 181 PPLTPGVLSLTSFTSVRSGYSHLPRRKRMSVAHMSLQAAAALLKGRSVLDATGQRCRVVK 240
PPLTPGVLSLTSFTSVRSGYSHLPRRKRMSVAHMSLQAAAALLKGRSVLDATGQRCRVVK
Sbjct: 181 PPLTPGVLSLTSFTSVRSGYSHLPRRKRMSVAHMSLQAAAALLKGRSVLDATGQRCRVVK 240
Query: 241 RSFAFPSFLEEDVVDGADTFDSSFFSKEEMSSMPDDVFESPPLSASYFRGIPHSASPVSP 300
RSFAFPSFLEEDVVDGADTFDSSFFSKEEMSSMPDDVFESPPLSASYFRGIPHSASPVSP
Sbjct: 241 RSFAFPSFLEEDVVDGADTFDSSFFSKEEMSSMPDDVFESPPLSASYFRGIPHSASPVSP 300
Query: 301 DGVQIPLKEYGRAPVPGPRRGKRIASKVKHFAFDRKKRHYGLGVVGNWLNRSYRRSISST 360
DGVQIPLKEYGRAPVPGPRRGKRIASKVKHFAFDRKKRHYGLGVVGNWLNRSYRRSISST
Sbjct: 301 DGVQIPLKEYGRAPVPGPRRGKRIASKVKHFAFDRKKRHYGLGVVGNWLNRSYRRSISST 360
Query: 361 VQRQLESFDSHRPYFTYWLTFVHVIITLLVICTYGIAPVGFAQHVTTQLVLRNKGVYESV 420
VQRQLESFDSHRPYFTYWLTFVHVIITLLVICTYGIAPVGFAQHVTTQLVLRNKGVYESV
Sbjct: 361 VQRQLESFDSHRPYFTYWLTFVHVIITLLVICTYGIAPVGFAQHVTTQLVLRNKGVYESV 420
Query: 421 KYIQQENFWVGPSSIDLIHLGAKFSPCIRKDGQIEQLVLRERDLERDSGCCVQNDHSGCI 480
KYIQQENFWVGPSSIDLIHLGAKFSPCIRKDGQIEQLVLRERDLERDSGCCVQNDHSGCI
Sbjct: 421 KYIQQENFWVGPSSIDLIHLGAKFSPCIRKDGQIEQLVLRERDLERDSGCCVQNDHSGCI 480
Query: 481 QTQRKDCSETLATFVKWQDDTGPPMDKSDLGQKRTSGAVCHQDPRTCEEPASSGAHIWPD 540
QTQRKDCSETLATFVKWQDDTGPPMDKSDLGQKRTSGAVCHQDPRTCEEPASSGAHIWPD
Sbjct: 481 QTQRKDCSETLATFVKWQDDTGPPMDKSDLGQKRTSGAVCHQDPRTCEEPASSGAHIWPD 540
Query: 541 DITKWPICTEQARSNHTGFLHMDCEIKGRPCCIGTKGSCEITTREYCEFMHGYFHEEATL 600
DITKWPICTEQARSNHTGFLHMDCEIKGRPCCIGTKGSCEITTREYCEFMHGYFHEEATL
Sbjct: 541 DITKWPICTEQARSNHTGFLHMDCEIKGRPCCIGTKGSCEITTREYCEFMHGYFHEEATL 600
Query: 601 CSQVHCLDKVCGLLPFLNPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAG 660
CSQVHCLDKVCGLLPFLNPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAG
Sbjct: 601 CSQVHCLDKVCGLLPFLNPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAG 660
Query: 661 WHRIAIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAF 720
WHRIAIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAF
Sbjct: 661 WHRIAIIFILSGITGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAF 720
Query: 721 LNLSAIVLFLFICGLLPWIDNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSL 780
LNLSAIVLFLFICGLLPWIDNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSL
Sbjct: 721 LNLSAIVLFLFICGLLPWIDNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSL 780
Query: 781 LAFAGLFAALVLWLYIYPINWPWIEHLTCFPFTSRFCEKYELDQVLH 827
LAFAGLFAALVLWLYIYPINWPWIEHLTCFPFTSRFCEKYELDQVLH
Sbjct: 781 LAFAGLFAALVLWLYIYPINWPWIEHLTCFPFTSRFCEKYELDQVLH 827
>gi|93352556 rhomboid, veinlet-like 6 isoform 1 [Homo sapiens]
Length = 856
Score = 1698 bits (4397), Expect = 0.0
Identities = 827/856 (96%), Positives = 827/856 (96%), Gaps = 29/856 (3%)
Query: 1 MASADKNGGSVSSVSSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPE---------- 50
MASADKNGGSVSSVSSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPE
Sbjct: 1 MASADKNGGSVSSVSSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPEGFQNRRLKKS 60
Query: 51 -------------------RKNPAYLKSVSLQEPRSRWQESSEKRPGFRRQASLSQSIRK 91
RKNPAYLKSVSLQEPRSRWQESSEKRPGFRRQASLSQSIRK
Sbjct: 61 QPRTWASHTTACPPSFLPKRKNPAYLKSVSLQEPRSRWQESSEKRPGFRRQASLSQSIRK 120
Query: 92 GAAQWFGVSGDWEGQRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKP 151
GAAQWFGVSGDWEGQRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKP
Sbjct: 121 GAAQWFGVSGDWEGQRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKP 180
Query: 152 CKMPKIVDPLARGRAFRHPEEMDRPHAPHPPLTPGVLSLTSFTSVRSGYSHLPRRKRMSV 211
CKMPKIVDPLARGRAFRHPEEMDRPHAPHPPLTPGVLSLTSFTSVRSGYSHLPRRKRMSV
Sbjct: 181 CKMPKIVDPLARGRAFRHPEEMDRPHAPHPPLTPGVLSLTSFTSVRSGYSHLPRRKRMSV 240
Query: 212 AHMSLQAAAALLKGRSVLDATGQRCRVVKRSFAFPSFLEEDVVDGADTFDSSFFSKEEMS 271
AHMSLQAAAALLKGRSVLDATGQRCRVVKRSFAFPSFLEEDVVDGADTFDSSFFSKEEMS
Sbjct: 241 AHMSLQAAAALLKGRSVLDATGQRCRVVKRSFAFPSFLEEDVVDGADTFDSSFFSKEEMS 300
Query: 272 SMPDDVFESPPLSASYFRGIPHSASPVSPDGVQIPLKEYGRAPVPGPRRGKRIASKVKHF 331
SMPDDVFESPPLSASYFRGIPHSASPVSPDGVQIPLKEYGRAPVPGPRRGKRIASKVKHF
Sbjct: 301 SMPDDVFESPPLSASYFRGIPHSASPVSPDGVQIPLKEYGRAPVPGPRRGKRIASKVKHF 360
Query: 332 AFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHVIITLLVI 391
AFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHVIITLLVI
Sbjct: 361 AFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHVIITLLVI 420
Query: 392 CTYGIAPVGFAQHVTTQLVLRNKGVYESVKYIQQENFWVGPSSIDLIHLGAKFSPCIRKD 451
CTYGIAPVGFAQHVTTQLVLRNKGVYESVKYIQQENFWVGPSSIDLIHLGAKFSPCIRKD
Sbjct: 421 CTYGIAPVGFAQHVTTQLVLRNKGVYESVKYIQQENFWVGPSSIDLIHLGAKFSPCIRKD 480
Query: 452 GQIEQLVLRERDLERDSGCCVQNDHSGCIQTQRKDCSETLATFVKWQDDTGPPMDKSDLG 511
GQIEQLVLRERDLERDSGCCVQNDHSGCIQTQRKDCSETLATFVKWQDDTGPPMDKSDLG
Sbjct: 481 GQIEQLVLRERDLERDSGCCVQNDHSGCIQTQRKDCSETLATFVKWQDDTGPPMDKSDLG 540
Query: 512 QKRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQARSNHTGFLHMDCEIKGRPC 571
QKRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQARSNHTGFLHMDCEIKGRPC
Sbjct: 541 QKRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQARSNHTGFLHMDCEIKGRPC 600
Query: 572 CIGTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGLLPFLNPEVPDQFYRLWLS 631
CIGTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGLLPFLNPEVPDQFYRLWLS
Sbjct: 601 CIGTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGLLPFLNPEVPDQFYRLWLS 660
Query: 632 LFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPYRAEVGP 691
LFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPYRAEVGP
Sbjct: 661 LFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPYRAEVGP 720
Query: 692 AGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLPWIDNIAHIFGFLSG 751
AGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLPWIDNIAHIFGFLSG
Sbjct: 721 AGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLPWIDNIAHIFGFLSG 780
Query: 752 LLLAFAFLPYITFGTSDKYRKRALILVSLLAFAGLFAALVLWLYIYPINWPWIEHLTCFP 811
LLLAFAFLPYITFGTSDKYRKRALILVSLLAFAGLFAALVLWLYIYPINWPWIEHLTCFP
Sbjct: 781 LLLAFAFLPYITFGTSDKYRKRALILVSLLAFAGLFAALVLWLYIYPINWPWIEHLTCFP 840
Query: 812 FTSRFCEKYELDQVLH 827
FTSRFCEKYELDQVLH
Sbjct: 841 FTSRFCEKYELDQVLH 856
>gi|190341097 rhomboid family 1 [Homo sapiens]
Length = 855
Score = 971 bits (2511), Expect = 0.0
Identities = 496/858 (57%), Positives = 603/858 (70%), Gaps = 55/858 (6%)
Query: 15 SSSRLQSRKPPNLSITIPPPEKETQAPGEQDSMLPERKNPAYLKSVSLQEPRSRWQESSE 74
S+S LQ +KPP L + IP T E+ S L + A+L+SVS+ +
Sbjct: 8 STSSLQRKKPPWLKLDIPSAVPLT---AEEPSFLQPLRRQAFLRSVSMPAETAHISSPHH 64
Query: 75 --KRPGFRRQASLSQSIRKGAAQWFGVSGDWEGQRQQWQRRSLHHCSMRYGRLKASCQRD 132
+RP +RQ S++Q+IR+G A WFGVS D + Q+WQR+S+ HCS RYG+LK R+
Sbjct: 65 ELRRPVLQRQTSITQTIRRGTADWFGVSKDSDST-QKWQRKSIRHCSQRYGKLKPQVLRE 123
Query: 133 LELPSQEAPSFQGTESPKP-----CK--MPKIVDPLARGRAFRHPEEM-DRPHAPHPPLT 184
L+LPSQ+ S TE+P P C+ M KI+DPLARGRAFR ++ + APH P+T
Sbjct: 124 LDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLSAPHTPVT 183
Query: 185 PGVLSLTSFTSVRSGYSHLPRR-KRMSVAHMSLQAAAALLKGRSVLDATGQRCRVVKRSF 243
PG SL SF+S RSG+ LPRR KR SVA MS +AAAAL+KGRSV D T +R + +RSF
Sbjct: 184 PGAASLCSFSSSRSGFHRLPRRRKRESVAKMSFRAAAALMKGRSVRDGTFRRAQ--RRSF 241
Query: 244 AFPSFLEEDVVDGADTFDSSFFSKE-----EMSSMPDDVFESPPLSA-SYFRGIPHSA-- 295
SFLEED D D D+SFF++E E+S+ PD+VFESP +A + P A
Sbjct: 242 TPASFLEEDTTDFPDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEKAPEQADL 301
Query: 296 -------SPVSPDGVQIPL-------KEYGRAPVP------------GPRRGKRIASKVK 329
S + + +PL KE AP P GPRRG+RIA V+
Sbjct: 302 TGGALDRSELERSHLMLPLERGWRKQKEGAAAPQPKVRLRQEVVSTAGPRRGQRIAVPVR 361
Query: 330 HFAFDRKKRHYGLGVVGNWLNRSYRRSISSTVQRQLESFDSHRPYFTYWLTFVHVIITLL 389
F R+KR YGLG+VG NR+YR+ I S V+RQ+E D HRP+FTYWLTFVH ++T+L
Sbjct: 362 KL-FAREKRPYGLGMVGRLTNRTYRKRIDSFVKRQIEDMDDHRPFFTYWLTFVHSLVTIL 420
Query: 390 VICTYGIAPVGFAQHVTTQLVLRNKGVYESVKYIQQENFWVGPSSIDLIHLGAKFSPCIR 449
+C YGIAPVGF+QH T VLRN+GVYE+VKY+QQENFW+GPSS LIHLGAKFSPC+R
Sbjct: 421 AVCIYGIAPVGFSQHETVDSVLRNRGVYENVKYVQQENFWIGPSSEALIHLGAKFSPCMR 480
Query: 450 KDGQIEQLVLRERDLERDSGCCVQNDHSGCIQTQRKDCSETLATFVKWQDDTGPPMDKSD 509
+D Q+ + R+ E+ S CCV+ND SGC+QT ++CS TLA +VKW P
Sbjct: 481 QDPQVHSFIRSAREREKHSACCVRNDRSGCVQTSEEECSSTLAVWVKWPIHPSAP---EL 537
Query: 510 LGQKRTSGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQARSNHTGFLHMDCEIKGR 569
G KR G+VCHQDPR C+EP+S H WP+DITKWPICT+ + NHT HMDC I GR
Sbjct: 538 AGHKRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSAGNHTNHPHMDCVITGR 597
Query: 570 PCCIGTKGSCEITTREYCEFMHGYFHEEATLCSQVHCLDKVCGLLPFLNPEVPDQFYRLW 629
PCCIGTKG CEIT+REYC+FM GYFHEEATLCSQVHC+D VCGLLPFLNPEVPDQFYRLW
Sbjct: 598 PCCIGTKGRCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLW 657
Query: 630 LSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPYRAEV 689
LSLFLHAG++HCLVS+ FQMT+LRDLEKLAGWHRIAII++LSG+TGNLASAIFLPYRAEV
Sbjct: 658 LSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEV 717
Query: 690 GPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLPWIDNIAHIFGFL 749
GPAGSQFG+LACLFVELFQSW +L RPW+AF L A+VLFLF GLLPWIDN AHI GF+
Sbjct: 718 GPAGSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLPWIDNFAHISGFI 777
Query: 750 SGLLLAFAFLPYITFGTSDKYRKRALILVSLLAFAGLFAALVLWLYIYPINWPWIEHLTC 809
SGL L+FAFLPYI+FG D YRKR I++ + F GL A LV+ Y+YP+ W E LTC
Sbjct: 778 SGLFLSFAFLPYISFGKFDLYRKRCQIIIFQVVFLGLLAGLVVLFYVYPVRCEWCEFLTC 837
Query: 810 FPFTSRFCEKYELDQVLH 827
PFT +FCEKYELD LH
Sbjct: 838 IPFTDKFCEKYELDAQLH 855
>gi|54144654 rhomboid protease 2 [Homo sapiens]
Length = 303
Score = 55.1 bits (131), Expect = 3e-07
Identities = 42/167 (25%), Positives = 78/167 (46%), Gaps = 17/167 (10%)
Query: 615 PFL-NPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGI 673
PF+ +PE ++ +R + +HAGV H L ++ Q+ + LE + R+ ++++ I
Sbjct: 109 PFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVI 168
Query: 674 TGNLASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFIC 733
G+LAS+IF P R VG +G + L+ F+ + ++ + + F L I++ +
Sbjct: 169 AGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAFGIFRLLIIILIIVLDM 228
Query: 734 GLLPW-----------IDNIAHIFGFLSGLLLAFAFLPYITFGTSDK 769
G + + AHI G +G+ + Y F DK
Sbjct: 229 GFALYRRFFVPEDGSPVSFAAHIAGGFAGMSIG-----YTVFSCFDK 270
>gi|21264326 rhomboid protease 3 [Homo sapiens]
Length = 404
Score = 53.5 bits (127), Expect = 8e-07
Identities = 34/155 (21%), Positives = 69/155 (44%), Gaps = 13/155 (8%)
Query: 618 NPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNL 677
+P++ Q +R +F+HAG+ H ++VV Q+ + LE + G RI ++++ + G+L
Sbjct: 204 HPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSL 263
Query: 678 ASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLP 737
A ++ VG +G + L++ + +W ++ +K A++ G
Sbjct: 264 AVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAV 323
Query: 738 WI-------------DNIAHIFGFLSGLLLAFAFL 759
W+ +AH+ G G+ L L
Sbjct: 324 WLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVL 358
>gi|4506525 rhomboid protease 1 [Homo sapiens]
Length = 438
Score = 43.1 bits (100), Expect = 0.001
Identities = 37/181 (20%), Positives = 72/181 (39%), Gaps = 17/181 (9%)
Query: 626 YRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNLASAIFLPY 685
+R +F+H G+ + + Q+ I LE + G RI+++++ + G+L +I
Sbjct: 246 WRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMR 305
Query: 686 RAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLPWI------ 739
VG +G + L + + +W + P+K + A+V G W+
Sbjct: 306 APVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPL 365
Query: 740 -------DNIAHIFGFLSGLLLAFAFLPYITFGTSDKYRKRALILVSLLAFAGLFAALVL 792
+AH+ G + G+ + L ++ R + V LLA+ V
Sbjct: 366 PASGPQPSFMAHLAGAVVGVSMGLTILR----SYEERLRDQCGWWVVLLAYGTFLLFAVF 421
Query: 793 W 793
W
Sbjct: 422 W 422
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 37.7 bits (86), Expect = 0.044
Identities = 55/217 (25%), Positives = 75/217 (34%), Gaps = 33/217 (15%)
Query: 2 ASADKNGGSVSSVSS-SRLQSRKPPN-----------LSITIPPPEKE-------TQAPG 42
+SA +G S SS SS SR +KPP LS + PP + T P
Sbjct: 351 SSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK 410
Query: 43 EQDSMLPERKNPAYLKSVSLQEPRSRWQESSEKRPGFRRQASLSQSIRK----------- 91
+ S P++ N VS+ R+ + + K R S + RK
Sbjct: 411 TRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKG 470
Query: 92 ---GAAQWFGVSGDWEGQRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTES 148
AA + Q QQ S S R K S ++ E+ + S + S
Sbjct: 471 GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSAS 530
Query: 149 PKPCKMPKIVDPLARGRAFRHPEEMDRPHAPHPPLTP 185
P P K K P R R P R +P P P
Sbjct: 531 PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPP 567
>gi|169213985 PREDICTED: similar to hCG2036794 [Homo sapiens]
Length = 518
Score = 35.8 bits (81), Expect = 0.17
Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 141 PSFQGTESPKPCKMPKIVDPLARGRAFRHPEEMDRPHAPHP--PLTPGVLSLTSFTSVRS 198
P F GT P+P K+P V F P D PHP P TP SLT TS+
Sbjct: 59 PEFPGTPYPEPSKLPHTVSLETFPLDFTEPLNPDLRETPHPESPETPKADSLT--TSISE 116
Query: 199 GYSHLPRRKRMSVAH 213
+P+ +AH
Sbjct: 117 SLD-MPKTNLSKMAH 130
>gi|239751846 PREDICTED: similar to hCG2036794 [Homo sapiens]
Length = 518
Score = 35.8 bits (81), Expect = 0.17
Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 141 PSFQGTESPKPCKMPKIVDPLARGRAFRHPEEMDRPHAPHP--PLTPGVLSLTSFTSVRS 198
P F GT P+P K+P V F P D PHP P TP SLT TS+
Sbjct: 59 PEFPGTPYPEPSKLPHTVSLETFPLDFTEPLNPDLRETPHPESPETPKADSLT--TSISE 116
Query: 199 GYSHLPRRKRMSVAH 213
+P+ +AH
Sbjct: 117 SLD-MPKTNLSKMAH 130
>gi|239746337 PREDICTED: similar to hCG2036794 [Homo sapiens]
Length = 518
Score = 35.8 bits (81), Expect = 0.17
Identities = 26/75 (34%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 141 PSFQGTESPKPCKMPKIVDPLARGRAFRHPEEMDRPHAPHP--PLTPGVLSLTSFTSVRS 198
P F GT P+P K+P V F P D PHP P TP SLT TS+
Sbjct: 59 PEFPGTPYPEPSKLPHTVSLETFPLDFTEPLNPDLRETPHPESPETPKADSLT--TSISE 116
Query: 199 GYSHLPRRKRMSVAH 213
+P+ +AH
Sbjct: 117 SLD-MPKTNLSKMAH 130
>gi|239742114 PREDICTED: similar to hCG2023245 [Homo sapiens]
Length = 329
Score = 33.1 bits (74), Expect = 1.1
Identities = 20/50 (40%), Positives = 22/50 (44%), Gaps = 4/50 (8%)
Query: 137 SQEAPSFQGTESPKPCKMPKIVDPLARGRAFRHPEEMDRPHAPHPPLTPG 186
SQE P+ E P MP AFR P DRP AP P +PG
Sbjct: 106 SQERPA----EESAPALMPSSAPRGPTEPAFRRPSSADRPLAPGPSSSPG 151
>gi|239755571 PREDICTED: hypothetical protein [Homo sapiens]
Length = 261
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 6/51 (11%)
Query: 137 SQEAPSFQGTESPKPCKMPK-IVDPLARGRAFRHPEEMDRPHAPHPPLTPG 186
S E P+ + T +P P P+ +P A R P DRP AP P +PG
Sbjct: 74 SNERPAEEPTPAPMPSSAPRGPTEP-----ALRRPSSADRPLAPGPSSSPG 119
>gi|239744417 PREDICTED: similar to hCG2023245 [Homo sapiens]
Length = 364
Score = 32.7 bits (73), Expect = 1.4
Identities = 19/51 (37%), Positives = 25/51 (49%), Gaps = 6/51 (11%)
Query: 137 SQEAPSFQGTESPKPCKMPK-IVDPLARGRAFRHPEEMDRPHAPHPPLTPG 186
S E P+ + T +P P P+ +P A R P DRP AP P +PG
Sbjct: 177 SNERPAEEPTPAPMPSSAPRGPTEP-----ALRRPSSADRPLAPGPSSSPG 222
>gi|65301141 PH domain and leucine rich repeat protein
phosphatase-like [Homo sapiens]
Length = 1323
Score = 32.3 bits (72), Expect = 1.8
Identities = 20/57 (35%), Positives = 29/57 (50%)
Query: 80 RRQASLSQSIRKGAAQWFGVSGDWEGQRQQWQRRSLHHCSMRYGRLKASCQRDLELP 136
RRQ SL+ S AQ + VS + + Q+WQR++ S R + SC E+P
Sbjct: 209 RRQYSLAFSSAGAQAQTYHVSFETLAEYQRWQRQASKVVSQRISTVDLSCYSLEEVP 265
>gi|7706589 GNAS complex locus NESP55 [Homo sapiens]
Length = 245
Score = 32.0 bits (71), Expect = 2.4
Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Query: 19 LQSRKPPNLSITIPPPEKETQAPGEQDSMLPERKNPAYLKSVSLQEPRSRWQESSEKRPG 78
L+ R P PP +E Q+P E + + PE K+P + + + + K+P
Sbjct: 166 LKLRSPDASPSRAPPSTQEPQSPREGEELKPEDKDPRDPEESKEPKEEKQRRRCKPKKP- 224
Query: 79 FRRQASLSQSIRKG 92
RR AS +KG
Sbjct: 225 TRRDASPESPSKKG 238
>gi|121949815 placenta-specific 4 [Homo sapiens]
Length = 150
Score = 32.0 bits (71), Expect = 2.4
Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 167 FRHPEEMDRPHAPHPPLTPGVLSLTSFTSVRSGYSH 202
F HP+ + P PH P P +L+L + T GY H
Sbjct: 65 FTHPDTLTHPGHPHSPWIPSLLTLDTLT--HPGYPH 98
>gi|4507161 SRY-box 11 [Homo sapiens]
Length = 441
Score = 31.6 bits (70), Expect = 3.1
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 10/81 (12%)
Query: 18 RLQSRKPPNLSITIPPPEKETQAPGEQDSMLPERKNPAYLKSVSLQEPRSRWQESSEKRP 77
+LQ ++ P+ PP ++ Q PG+Q S L R N A + P S SS + P
Sbjct: 236 QLQIKQEPDEEDEEPPHQQLLQPPGQQPSQLLRRYNVA-------KVPASPTLSSSAESP 288
Query: 78 GFRRQASLSQSIRKGAAQWFG 98
ASL +R GA G
Sbjct: 289 ---EGASLYDEVRAGATSGAG 306
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 31.2 bits (69), Expect = 4.1
Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 17/87 (19%)
Query: 516 SGAVCHQDPRTCEEPASSGAHIWPDDITKWPICTEQARSNHTGFLHM----DCEIKGRPC 571
+G +CH + P + G++ + + ICT S +TG +C + PC
Sbjct: 366 TGLLCHLNDACISNPCNEGSNCDTNPVNGKAICT--CPSGYTGPACSQDVDECSLGANPC 423
Query: 572 -----CIGTKGSCEITTREYCEFMHGY 593
CI T GS E C+ + GY
Sbjct: 424 EHAGKCINTLGSFE------CQCLQGY 444
>gi|13899309 ribosomal protein S6 kinase-like 1 [Homo sapiens]
Length = 541
Score = 31.2 bits (69), Expect = 4.1
Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 6 KNGGSVSSVSSSRLQSRKPPNLSITIPPPEKETQAPGEQDSML-PERKNPAYLKSVSLQE 64
++ G S + R++++ P+L++ P APG+ L P R +P L ++ +
Sbjct: 205 RHSGLSSGSTQERMKAQLNPHLNLLTPARLPSGHAPGQDRIALEPPRTSPNLL--LAGEA 262
Query: 65 PRSRWQESSEKRPGFRRQASLSQSIRK 91
P +R Q +E P R S S + K
Sbjct: 263 PSTRPQREAEGEPTARTSTSGSSDLPK 289
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 31.2 bits (69), Expect = 4.1
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 7/59 (11%)
Query: 4 ADKNGGSVSSVSSSRLQSRKPPNLSI-------TIPPPEKETQAPGEQDSMLPERKNPA 55
A G S +S + R + +PP+L T PP KETQ +++S++P +N A
Sbjct: 2112 AYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA 2170
>gi|45827755 transforming, acidic coiled-coil containing protein 2
isoform b [Homo sapiens]
Length = 1094
Score = 31.2 bits (69), Expect = 4.1
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 7/59 (11%)
Query: 4 ADKNGGSVSSVSSSRLQSRKPPNLSI-------TIPPPEKETQAPGEQDSMLPERKNPA 55
A G S +S + R + +PP+L T PP KETQ +++S++P +N A
Sbjct: 258 AYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA 316
>gi|45827753 transforming, acidic coiled-coil containing protein 2
isoform c [Homo sapiens]
Length = 996
Score = 31.2 bits (69), Expect = 4.1
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 7/59 (11%)
Query: 4 ADKNGGSVSSVSSSRLQSRKPPNLSI-------TIPPPEKETQAPGEQDSMLPERKNPA 55
A G S +S + R + +PP+L T PP KETQ +++S++P +N A
Sbjct: 190 AYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA 248
>gi|11119414 transforming, acidic coiled-coil containing protein 2
isoform d [Homo sapiens]
Length = 1026
Score = 31.2 bits (69), Expect = 4.1
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 7/59 (11%)
Query: 4 ADKNGGSVSSVSSSRLQSRKPPNLSI-------TIPPPEKETQAPGEQDSMLPERKNPA 55
A G S +S + R + +PP+L T PP KETQ +++S++P +N A
Sbjct: 190 AYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEESLVPSGENLA 248
>gi|223671872 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform c [Homo sapiens]
Length = 320
Score = 30.8 bits (68), Expect = 5.4
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 106 QRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKPCKMPKIVDPLARGR 165
++++ + L Y +LKASCQ + + +++P P + PLA
Sbjct: 225 EKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPS 284
Query: 166 AFRHPEE 172
R P E
Sbjct: 285 QRRSPPE 291
>gi|223671870 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform b [Homo sapiens]
Length = 487
Score = 30.8 bits (68), Expect = 5.4
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 106 QRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKPCKMPKIVDPLARGR 165
++++ + L Y +LKASCQ + + +++P P + PLA
Sbjct: 392 EKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPS 451
Query: 166 AFRHPEE 172
R P E
Sbjct: 452 QRRSPPE 458
>gi|4504631 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform a [Homo sapiens]
Length = 419
Score = 30.8 bits (68), Expect = 5.4
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 106 QRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKPCKMPKIVDPLARGR 165
++++ + L Y +LKASCQ + + +++P P + PLA
Sbjct: 324 EKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPS 383
Query: 166 AFRHPEE 172
R P E
Sbjct: 384 QRRSPPE 390
>gi|153792133 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform a [Homo sapiens]
Length = 419
Score = 30.8 bits (68), Expect = 5.4
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 106 QRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKPCKMPKIVDPLARGR 165
++++ + L Y +LKASCQ + + +++P P + PLA
Sbjct: 324 EKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPS 383
Query: 166 AFRHPEE 172
R P E
Sbjct: 384 QRRSPPE 390
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 30.8 bits (68), Expect = 5.4
Identities = 38/183 (20%), Positives = 68/183 (37%), Gaps = 30/183 (16%)
Query: 6 KNGGSVSSVSSSRLQSRKPPNLS---ITIPPPEKET--------------QAPGEQDSML 48
K G S L +KP +LS I P P E QA + S+L
Sbjct: 516 KAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVL 575
Query: 49 PERKNPAYLKSVSLQEPRSRWQESSEKRPGFRRQASLSQ----------SIRKGAAQWFG 98
P + P+ L Q+ + + Q+ +++ ++Q Q S ++ Q
Sbjct: 576 PSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSS 635
Query: 99 VSGDWEGQRQQWQRRSLHHCSMRYGRLKASCQRDLELPSQEAPSFQGTESPKPCKMPKIV 158
+S Q+QQ Q++ + + + Q+ P+Q PS SP P + ++
Sbjct: 636 ISAQ---QQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLL 692
Query: 159 DPL 161
+
Sbjct: 693 QQM 695
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 30.8 bits (68), Expect = 5.4
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 24 PPNLSITIPPPEKETQAPGEQDSMLPERKNPAYLKSVSLQEPRSRWQESSEKRPGF 79
PP S PPPE +P E+ + P ++P S +L+ P S E+S P F
Sbjct: 497 PPEESPLSPPPESSPFSPLEESPLSPPEESP---PSPALETPLSPPPEASPLSPPF 549
>gi|73747881 zinc finger, ZZ type with EF hand domain 1 [Homo sapiens]
Length = 2961
Score = 30.8 bits (68), Expect = 5.4
Identities = 21/66 (31%), Positives = 28/66 (42%), Gaps = 5/66 (7%)
Query: 136 PSQEAPSFQGTESPKPCKMPKIVDPLARGRAFRHPEEMDRPHAP-----HPPLTPGVLSL 190
P++ AP G +SP PK+ A P + P +P PP T G L L
Sbjct: 1476 PTEAAPPATGDQSPGLGTQPKLPSSSGLPAADVSPATAEEPLSPSTPTRRPPFTRGRLRL 1535
Query: 191 TSFTSV 196
SF S+
Sbjct: 1536 LSFRSM 1541
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,251,785
Number of Sequences: 37866
Number of extensions: 1773345
Number of successful extensions: 5594
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 5515
Number of HSP's gapped (non-prelim): 96
length of query: 827
length of database: 18,247,518
effective HSP length: 111
effective length of query: 716
effective length of database: 14,044,392
effective search space: 10055784672
effective search space used: 10055784672
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.