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Search of human proteins with 93141033
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|93141033 PAX interacting protein 1 [Homo sapiens]
(1069 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|93141033 PAX interacting protein 1 [Homo sapiens] 2165 0.0
gi|221139761 zinc finger protein 853 [Homo sapiens] 124 5e-28
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 114 5e-25
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 110 9e-24
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 110 9e-24
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 109 2e-23
gi|33286444 mastermind-like 2 [Homo sapiens] 99 3e-20
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 98 4e-20
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 94 5e-19
gi|110347429 mediator complex subunit 12 [Homo sapiens] 93 1e-18
gi|226246533 TOX high mobility group box family member 3 isoform... 91 4e-18
gi|226054295 TOX high mobility group box family member 3 isoform... 91 4e-18
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 90 1e-17
gi|44890059 involucrin [Homo sapiens] 85 3e-16
gi|18644886 forkhead box P1 isoform 1 [Homo sapiens] 84 7e-16
gi|93277088 mediator of RNA polymerase II transcription, subunit... 83 1e-15
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 83 1e-15
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 83 1e-15
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho... 83 1e-15
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho... 83 1e-15
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom... 83 1e-15
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 80 8e-15
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens] 79 3e-14
gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens] 79 3e-14
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 78 5e-14
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 77 7e-14
gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 77 7e-14
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 75 3e-13
gi|148746195 trichohyalin [Homo sapiens] 75 4e-13
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 74 7e-13
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 2165 bits (5610), Expect = 0.0
Identities = 1069/1069 (100%), Positives = 1069/1069 (100%)
Query: 1 MSDQAPKVPEEMFREVKYYAVGDIDPQVIQLLKAGKAKEVSYNALASHIISEDGDNPEVG 60
MSDQAPKVPEEMFREVKYYAVGDIDPQVIQLLKAGKAKEVSYNALASHIISEDGDNPEVG
Sbjct: 1 MSDQAPKVPEEMFREVKYYAVGDIDPQVIQLLKAGKAKEVSYNALASHIISEDGDNPEVG 60
Query: 61 EAREVFDLPVVKPSWVILSVQCGTLLPVNGFSPESCQIFFGITACLSQVSSEDRSALWAL 120
EAREVFDLPVVKPSWVILSVQCGTLLPVNGFSPESCQIFFGITACLSQVSSEDRSALWAL
Sbjct: 61 EAREVFDLPVVKPSWVILSVQCGTLLPVNGFSPESCQIFFGITACLSQVSSEDRSALWAL 120
Query: 121 VTFYGGDCQLTLNKKCTHLIVPEPKGEKYECALKRASIKIVTPDWVLDCVSEKTKKDEAF 180
VTFYGGDCQLTLNKKCTHLIVPEPKGEKYECALKRASIKIVTPDWVLDCVSEKTKKDEAF
Sbjct: 121 VTFYGGDCQLTLNKKCTHLIVPEPKGEKYECALKRASIKIVTPDWVLDCVSEKTKKDEAF 180
Query: 181 YHPRLIIYEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNT 240
YHPRLIIYEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNT
Sbjct: 181 YHPRLIIYEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNT 240
Query: 241 EKSKGELMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVP 300
EKSKGELMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVP
Sbjct: 241 EKSKGELMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVP 300
Query: 301 GNILPPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHIL 360
GNILPPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHIL
Sbjct: 301 GNILPPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHIL 360
Query: 361 QTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQ 420
QTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQ
Sbjct: 361 QTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQ 420
Query: 421 PQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQ 480
PQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQ
Sbjct: 421 PQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQ 480
Query: 481 LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRM 540
LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRM
Sbjct: 481 LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRM 540
Query: 541 HQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEI 600
HQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEI
Sbjct: 541 HQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEI 600
Query: 601 PEEGFLLGCVFAIADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSA 660
PEEGFLLGCVFAIADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSA
Sbjct: 601 PEEGFLLGCVFAIADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSA 660
Query: 661 YAQAIRERKRCVTAHWLNTVLKKKKMVPPHRALHFPVAFPPGGKPCSQHIISVTGFVDSD 720
YAQAIRERKRCVTAHWLNTVLKKKKMVPPHRALHFPVAFPPGGKPCSQHIISVTGFVDSD
Sbjct: 661 YAQAIRERKRCVTAHWLNTVLKKKKMVPPHRALHFPVAFPPGGKPCSQHIISVTGFVDSD 720
Query: 721 RDDLKLMAYLAGAKYTGYLCRSNTVLICKEPTGLKYEKAKEWRIPCVNAQWLGDILLGNF 780
RDDLKLMAYLAGAKYTGYLCRSNTVLICKEPTGLKYEKAKEWRIPCVNAQWLGDILLGNF
Sbjct: 721 RDDLKLMAYLAGAKYTGYLCRSNTVLICKEPTGLKYEKAKEWRIPCVNAQWLGDILLGNF 780
Query: 781 EALRQIQYSRYTAFSLQDPFAPTQHLVLNLLDAWRVPLKVSAELLMSIRLPPKLKQNEVA 840
EALRQIQYSRYTAFSLQDPFAPTQHLVLNLLDAWRVPLKVSAELLMSIRLPPKLKQNEVA
Sbjct: 781 EALRQIQYSRYTAFSLQDPFAPTQHLVLNLLDAWRVPLKVSAELLMSIRLPPKLKQNEVA 840
Query: 841 NVQPSSKRARIEDVPPPTKKLTPELTPFVLFTGFEPVQVQQYIKKLYILGGEVAESAQKC 900
NVQPSSKRARIEDVPPPTKKLTPELTPFVLFTGFEPVQVQQYIKKLYILGGEVAESAQKC
Sbjct: 841 NVQPSSKRARIEDVPPPTKKLTPELTPFVLFTGFEPVQVQQYIKKLYILGGEVAESAQKC 900
Query: 901 THLIASKVTRTVKFLTAISVVKHIVTPEWLEECFRCQKFIDEQNYILRDAEAEVLFSFSL 960
THLIASKVTRTVKFLTAISVVKHIVTPEWLEECFRCQKFIDEQNYILRDAEAEVLFSFSL
Sbjct: 901 THLIASKVTRTVKFLTAISVVKHIVTPEWLEECFRCQKFIDEQNYILRDAEAEVLFSFSL 960
Query: 961 EESLKRAHVSPLFKAKYFYITPGICPSLSTMKAIVECAGGKVLSKQPSFRKLMEHKQNSS 1020
EESLKRAHVSPLFKAKYFYITPGICPSLSTMKAIVECAGGKVLSKQPSFRKLMEHKQNSS
Sbjct: 961 EESLKRAHVSPLFKAKYFYITPGICPSLSTMKAIVECAGGKVLSKQPSFRKLMEHKQNSS 1020
Query: 1021 LSEIILISCENDLHLCREYFARGIDVHNAEFVLTGVLTQTLDYESYKFN 1069
LSEIILISCENDLHLCREYFARGIDVHNAEFVLTGVLTQTLDYESYKFN
Sbjct: 1021 LSEIILISCENDLHLCREYFARGIDVHNAEFVLTGVLTQTLDYESYKFN 1069
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 124 bits (311), Expect = 5e-28
Identities = 93/224 (41%), Positives = 119/224 (53%), Gaps = 25/224 (11%)
Query: 360 LQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHL 419
L+ P ++ +QQ++ QQ +V ++K PE ++ QQQQ Q QQ Q
Sbjct: 116 LELQQQPQQDGQQQLSQLQQ--EKHQSVHHQELK--PELQLMHQQQQLQPQQVQEQQRLQ 171
Query: 420 QPQQIMQLQQQQQQQI-SQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPP 478
Q Q+ +Q QQ Q+QQ+ QQ QQ QQQQ+Q Q QQQ Q QQQ
Sbjct: 172 QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQ 231
Query: 479 QQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQ----QLAQLQQQHSLLQQQQQQQIQQ 534
Q+ + QQQL QQQ LQQQ Q QQ QLQQQ Q AQLQQQ L QQ+Q QQ QQ
Sbjct: 232 QEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQ 291
Query: 535 QQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQ 578
QQL QQQQ+Q+Q Q Q Q PP +P ++++
Sbjct: 292 QQLL----QQQQEQLQQQ------------QLQPPPLEPEEEEE 319
Score = 119 bits (297), Expect = 2e-26
Identities = 112/292 (38%), Positives = 136/292 (46%), Gaps = 32/292 (10%)
Query: 333 PAVRTLRNITNNADIQQMNRPS--NVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFS 390
P TL + ++ Q+ P N + +SAP E +++ +
Sbjct: 37 PGPDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEI----AEETRPGQRELQLQ 92
Query: 391 QVKVTPETHMLQQQQQAQQQQQQHPVLHLQ--PQQIMQLQQQQQQQISQQPYPQQPPHPF 448
Q++ PE QQQ Q +Q QQ P L LQ PQQ Q Q Q QQ Q Q P
Sbjct: 93 QLEQQPEP---QQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPE 149
Query: 449 SQQQQQQQQAHPHQFSQQQ-LQFPQQQLHPPQ----QLHRPQQQLQP-FQQQHALQQQFH 502
Q QQQQ P Q +QQ LQ Q+QL Q Q+ + Q+QLQ Q+Q LQQQ
Sbjct: 150 LQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQE 209
Query: 503 QLQQHQL-------QQQQL----AQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQS 551
QLQQ QL QQQQ QLQQQ LL QQQ Q+QQQ LQ+ Q QQQ ++
Sbjct: 210 QLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQ 269
Query: 552 QTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEIPEE 603
Q A Q LQ Q QQ QQQ QQ QQ QL P +E EE
Sbjct: 270 QQAQ--LQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQL--QPPPLEPEEE 317
Score = 119 bits (297), Expect = 2e-26
Identities = 99/260 (38%), Positives = 119/260 (45%), Gaps = 31/260 (11%)
Query: 345 ADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQ 404
++I + RP LQ L + +QQ H Q + L Q + + + Q Q
Sbjct: 76 SEIAEETRPGQRELQLQQLEQQPEP-QQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQ 134
Query: 405 QQAQQQ----------QQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQ 454
Q+ Q Q H LQPQQ+ + Q+ QQQQ Q Q QQ+Q
Sbjct: 135 QEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQL 194
Query: 455 QQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQL 514
QQQ Q QQQ Q+QL QQ Q QQQ LQQQ Q QQ QLQQQQ
Sbjct: 195 QQQVQEQQLLQQQ----QEQL----------QQQQLLQQQEQLQQQQFQQQQEQLQQQQQ 240
Query: 515 AQLQQQHSLLQQQ--QQQQIQ-QQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQ 571
L QQ LQQQ QQQQ Q QQQL Q Q QQQ+ Q L Q Q Q + Q
Sbjct: 241 LLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQ--QQLLQQQ 298
Query: 572 QPPQQQQQQQPPP-SPQQHQ 590
Q QQQQ QPPP P++ +
Sbjct: 299 QEQLQQQQLQPPPLEPEEEE 318
Score = 114 bits (284), Expect = 6e-25
Identities = 97/285 (34%), Positives = 134/285 (47%), Gaps = 58/285 (20%)
Query: 348 QQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQA 407
Q++ + H Q L P + EQQ QQ Q + E +LQQQ+Q
Sbjct: 144 QELKPELQLMHQQQQLQ-PQQVQEQQRLQQQQEQL--------QTQQAQEQQVLQQQEQL 194
Query: 408 QQQQQQHPVLHLQPQQIMQLQ-QQQQQQISQQPYPQQPPHPFSQQQ----QQQQQAHPHQ 462
QQQ Q+ +L Q +Q+ Q Q QQQ+Q+ QQ + QQ QQQ QQQ Q
Sbjct: 195 QQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL 254
Query: 463 FSQQQLQFPQQQLHPPQQ------LHRPQQQLQPFQQQHALQQQFHQLQQHQLQ------ 510
QQQ Q QQ L Q L + Q+QLQ QQQ LQQQ QLQQ QLQ
Sbjct: 255 LQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEP 314
Query: 511 ---------------------QQQLAQLQQQHSLLQQQQQQQIQ---QQQLQRMHQQQQQ 546
+QQ +L++Q L +QQ+Q+Q+Q Q++LQ++ QQ +Q
Sbjct: 315 EEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQ 374
Query: 547 QQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQL 591
QQ Q + Q +Q ++ P + QQQ+ Q +P Q +L
Sbjct: 375 QQQQLE--------QQEVQLELTPVELGAQQQEVQLELTPVQPEL 411
Score = 101 bits (251), Expect = 4e-21
Identities = 85/255 (33%), Positives = 121/255 (47%), Gaps = 31/255 (12%)
Query: 347 IQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQ 406
+Q+ R LQT A + + QQ QQ +L Q + + +LQQQ+Q
Sbjct: 164 VQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQ-QVQEQQLLQQQQEQLQQQQLLQQQEQ 222
Query: 407 AQQQQQQHPVLHLQPQQIM-----------QLQQQQQQQISQQPYPQQPPHPFSQ----- 450
QQQQ Q LQ QQ + QL QQQQ Q+ QQ QQ Q
Sbjct: 223 LQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQ 282
Query: 451 ----QQQQQQQAHPHQFSQQQLQFPQQQLHPP--QQLHRPQQQLQPFQQQHALQQQFHQL 504
QQQQQQQ QQQ Q QQQL PP + + +L+ +Q+ Q
Sbjct: 283 QEQLQQQQQQQL----LQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQ- 337
Query: 505 QQHQLQQQQLAQLQQQHSLLQQQQQQQIQQ--QQLQRMHQQQQQQQMQSQTAP-HLSQTS 561
Q+ +L++QQ + QQ+ LQ + Q+++QQ QQL++ QQ +QQ++Q + P L
Sbjct: 338 QRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQ 397
Query: 562 QALQHQVPPQQPPQQ 576
Q +Q ++ P QP Q
Sbjct: 398 QEVQLELTPVQPELQ 412
Score = 79.3 bits (194), Expect = 2e-14
Identities = 60/186 (32%), Positives = 93/186 (50%), Gaps = 18/186 (9%)
Query: 370 LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQ 429
L+QQ+ QQ + Q ++ + +LQQQ+Q QQQQQQ QL Q
Sbjct: 250 LQQQLLQQQQAQLQQQLLEQQQAQLQQQL-LLQQQEQLQQQQQQ------------QLLQ 296
Query: 430 QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
QQQ+Q+ QQ P P +++ + + S+Q+L+ +Q+L Q+L R Q+Q
Sbjct: 297 QQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQR- 355
Query: 490 PFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQM 549
Q Q LQ++ QL+Q QQQQ QL+QQ L+ + QQQ ++ Q ++
Sbjct: 356 --QLQLKLQEELQQLEQQLEQQQQ--QLEQQEVQLELTPVELGAQQQEVQLELTPVQPEL 411
Query: 550 QSQTAP 555
Q + P
Sbjct: 412 QLELVP 417
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 114 bits (285), Expect = 5e-25
Identities = 101/281 (35%), Positives = 118/281 (41%), Gaps = 47/281 (16%)
Query: 348 QQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQA 407
QQ + H+L ++ ++QQ TN Q + P +H QQ
Sbjct: 3736 QQQQQQQQQQHLLGQVA-----IQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQL 3790
Query: 408 QQQQQQHPVLHLQPQQIMQLQQQQ----------------------QQQISQQPYPQQPP 445
Q Q P L P Q+ LQQQ Q++QQ
Sbjct: 3791 SPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGH 3850
Query: 446 HPFSQQQQQQQQAHPHQFSQQQLQFPQQQL-----------HPPQQLHRPQQQLQPFQQQ 494
+ QQQQQQQ H Q S L QQ L P L + QQQ Q QQQ
Sbjct: 3851 RLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQ 3910
Query: 495 HALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTA 554
QQQ QLQQ Q QQQ Q QQQ LQQQQQQQ+QQQQ Q++ QQQQQQQ Q Q
Sbjct: 3911 QLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQ-QQLQQQQQQQQQQFQ-- 3967
Query: 555 PHLSQTSQALQHQVPPQQPPQQQQQQQ------PPPSPQQH 589
Q L +Q PQQQQQQQ P P QH
Sbjct: 3968 QQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQH 4008
Score = 95.9 bits (237), Expect = 2e-19
Identities = 103/296 (34%), Positives = 126/296 (42%), Gaps = 63/296 (21%)
Query: 353 PSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQ 412
P N+A L++L ++ L+++ QQ L Q + + L Q QQQQQ
Sbjct: 3701 PGNLA--LRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQ 3758
Query: 413 QHP------VLHLQPQQIMQLQQQQQ---QQISQQPYPQQP-----PHPFSQQQQQQQQA 458
Q P L +PQ +M Q QQ+S QP PQ P P + QQQ A
Sbjct: 3759 QGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP-PQGPQGMLGPAQVAVLQQQHPGA 3817
Query: 459 HPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQ---------- 508
Q +Q+ Q ++ QL + Q L + A QQQ Q QQHQ
Sbjct: 3818 LGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQ--QQQQHQQQGSMAGLSH 3875
Query: 509 LQQQ----------------QLAQLQQQHSLLQQQQQQQIQQQQL--------QRMHQQQ 544
LQQ L QLQQQ L QQQQ QQ QQQQL Q++ QQQ
Sbjct: 3876 LQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQ 3935
Query: 545 QQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPP----------SPQQHQ 590
QQQQ+Q Q L Q Q LQ Q QQ QQQQQQ SPQQ Q
Sbjct: 3936 QQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQ 3991
Score = 85.1 bits (209), Expect = 3e-16
Identities = 87/259 (33%), Positives = 105/259 (40%), Gaps = 54/259 (20%)
Query: 371 EQQVNHSQQG------HTNANAVLFS-QVKVTPETH-MLQQQQQAQQQQQQHPVLHLQPQ 422
+QQ H QQG H + + S Q K++ + LQQ QQ QQ QQQ + Q Q
Sbjct: 3859 QQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQ 3918
Query: 423 QIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLH 482
Q+ Q QQ QQQQ+ QQ QQQQQ QQ Q QQQ Q QQQ QQ
Sbjct: 3919 QLQQQQQLQQQQLQQQ-----------QQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQ 3967
Query: 483 RPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLA--------QLQQQHS--------LLQQ 526
+ QQQ QQ L Q L Q QQQQ+A LQ S LL
Sbjct: 3968 QQQQQ----QQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTG 4023
Query: 527 QQQQQI------QQQQLQRMHQ---------QQQQQQMQSQTAPHLSQTSQALQHQVPPQ 571
++Q + + + HQ + + P LS SQ L Q PQ
Sbjct: 4024 KEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQ 4083
Query: 572 QPPQQQQQQQPPPSPQQHQ 590
P Q Q P P Q Q
Sbjct: 4084 PQPSSLQLQPPLRLPGQQQ 4102
Score = 65.9 bits (159), Expect = 2e-10
Identities = 80/240 (33%), Positives = 95/240 (39%), Gaps = 53/240 (22%)
Query: 394 VTPETHMLQQQ-QQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQP------YPQQPPH 446
VT + +Q+Q Q ++QQ++H L + + Q QQQQQQQ QQ P Q P
Sbjct: 3567 VTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPR 3626
Query: 447 PFSQQQQQQQQAHPHQFSQQQ--------------LQFPQQQLHPPQQLHRPQQQLQPFQ 492
++ Q H Q Q + P Q P QQQ Q
Sbjct: 3627 LLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQ----Q 3682
Query: 493 QQH----------------------ALQQQFHQLQQHQLQ-QQQLAQLQQQHSLLQQQQQ 529
QQH +L LQ+ QLQ QQQ QL Q+ LQQQQQ
Sbjct: 3683 QQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQK---LQQQQQ 3739
Query: 530 QQIQQQQL--QRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQ 587
QQ QQQ L Q QQQQQQ QT L Q L Q QQ QPP PQ
Sbjct: 3740 QQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQ 3799
Score = 58.9 bits (141), Expect = 2e-08
Identities = 77/256 (30%), Positives = 97/256 (37%), Gaps = 55/256 (21%)
Query: 373 QVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHP-VLHLQPQQIMQLQQQQ 431
QV Q+ HTN A ++ + QQQQQ QQQQQQH VL L P Q +L +
Sbjct: 3580 QVRKQQKEHTNLMAEYRNKQQ--------QQQQQQQQQQQQHSAVLALSPSQSPRLLTKL 3631
Query: 432 QQQI----SQQP--------------------YPQQPPHPF-----SQQQQQQQQAHPHQ 462
Q+ QP P QP PF +QQQQQQ
Sbjct: 3632 PGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGS 3691
Query: 463 FSQQQLQF-----------PQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQ 511
+ F P +L +QL QQ++Q Q+ LQQQ Q QQ Q
Sbjct: 3692 LAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQK---LQQQQQQQQQQQHLL 3748
Query: 512 QQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQ 571
Q+A QQQ Q Q + + M Q + Q +P Q Q Q + P
Sbjct: 3749 GQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSP---QPPQGPQGMLGPA 3805
Query: 572 QPPQQQQQQQPPPSPQ 587
Q QQQ PQ
Sbjct: 3806 QVAVLQQQHPGALGPQ 3821
Score = 47.8 bits (112), Expect = 6e-05
Identities = 53/206 (25%), Positives = 85/206 (41%), Gaps = 27/206 (13%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPP------HPFSQQQQQQ 455
QQ Q+ P LQ Q++ QP P P + Q+Q ++
Sbjct: 3453 QQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYEE 3512
Query: 456 QQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQL------------QPFQQQHALQQQFHQ 503
H Q Q QL+ ++Q+ +HR ++ + F + A + +
Sbjct: 3513 WLFHTQQLLQMQLKVLEEQIG----VHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVT 3568
Query: 504 LQQHQLQQQ--QLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTS 561
QQ ++Q+Q Q+ + Q++H+ L + + + QQQQ Q QQQQQQQ + A SQ+
Sbjct: 3569 EQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQ---QQQQQQQHSAVLALSPSQSP 3625
Query: 562 QALQHQVPPQQPPQQQQQQQPPPSPQ 587
+ L P Q Q PP Q
Sbjct: 3626 RLLTKLPGQLLPGHGLQPPQGPPGGQ 3651
Score = 45.1 bits (105), Expect = 4e-04
Identities = 45/175 (25%), Positives = 64/175 (36%), Gaps = 8/175 (4%)
Query: 401 LQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQP---PHPFSQQQ--QQQ 455
L + ++ + Q++Q LQP Q Q QQQQQ + P P Q PH S Q
Sbjct: 3252 LLEHEKKELQKKQQLSAQLQPAQQQQ-QQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQ 3310
Query: 456 QQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLA 515
QQ +Q PQ + H QQ+L P + Q H L Q L
Sbjct: 3311 QQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAP--SMAMVSNQGHMLSGQHGGQAGLV 3368
Query: 516 QLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPP 570
Q +L Q+ + + Q QQQ+ + P A + + P
Sbjct: 3369 PQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDP 3423
Score = 41.6 bits (96), Expect = 0.004
Identities = 48/172 (27%), Positives = 65/172 (37%), Gaps = 6/172 (3%)
Query: 409 QQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPH-PFSQQQQQQQQAHPHQFSQQQ 467
Q Q Q L LQP ++L QQQQQ+S H + + PH +Q
Sbjct: 4081 QPQPQPSSLQLQPP--LRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPS 4138
Query: 468 LQFPQQQLHPPQQLHRPQQQL--QPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQ 525
+ Q Q L PQQ + +P Q Q Q + L+
Sbjct: 4139 VSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLR 4198
Query: 526 QQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQ 577
Q Q + + R QQQQQ+Q+ Q SQA++ Q PP Q P Q
Sbjct: 4199 AQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVR-QTPPYQEPGTQ 4249
Score = 38.5 bits (88), Expect = 0.034
Identities = 41/162 (25%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 502 HQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTS 561
H+ ++ Q +QQ AQLQ QQQQQQQ Q L Q ++P L+ +
Sbjct: 3255 HEKKELQKKQQLSAQLQPA----QQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQ 3310
Query: 562 QALQHQVPPQQPPQQQQQQQP--PPSPQQHQLFGHDPAVEIPEEGFLLGCVFAIADYPEQ 619
Q L + + P Q P PP+ Q A+ + L G A Q
Sbjct: 3311 QQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQ 3370
Query: 620 MSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSAY 661
S + +L+ Q GT+ P+ + L + Q+++++
Sbjct: 3371 QSSQPVLS------QKPMGTMPPSMCMKPQQLAMQQQLANSF 3406
Score = 36.6 bits (83), Expect = 0.13
Identities = 82/409 (20%), Positives = 145/409 (35%), Gaps = 16/409 (3%)
Query: 191 EEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFD 250
+++++ ++++++ ++Q Q + ++ Q QQ + ++ + L+
Sbjct: 3921 QQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQ 3980
Query: 251 DSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRG 310
+ SP++Q++ +P P P L+ V + G
Sbjct: 3981 SRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEG 4040
Query: 311 NLMAAGQNLQSSERSEMIATWSPAVR-TLRNITNNADIQQMNRPSNVAHILQTLSAPTKN 369
G L E +AT V+ +L + +Q +P + LQ
Sbjct: 4041 PSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQ 4100
Query: 370 LEQQVN--HSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQL 427
+QQV+ H+ G ++ S + + H+L Q + Q +L Q L
Sbjct: 4101 QQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPML 4160
Query: 428 QQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLH---RP 484
++ Q QP P+ P S Q P Q + Q PQ H +
Sbjct: 4161 ERPMQNNTGPQP-PKPGPVLQSGQGLPGVGIMP-TVGQLRAQLQGVLAKNPQLRHLSPQQ 4218
Query: 485 QQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQ----QQIQQQQLQRM 540
QQQLQ Q LQQ ++Q Q+ Q LL Q Q Q LQ +
Sbjct: 4219 QQQLQALLMQRQLQQS-QAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQEL 4277
Query: 541 HQQQQQQQMQSQTAPHLSQTSQALQ---HQVPPQQPPQQQQQQQPPPSP 586
+ Q AP + ++ + H PP PQ+ ++ PSP
Sbjct: 4278 GAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP 4326
Score = 32.3 bits (72), Expect = 2.5
Identities = 41/201 (20%), Positives = 80/201 (39%), Gaps = 25/201 (12%)
Query: 412 QQHPVLHLQPQQIMQLQQQQQQQISQQPY-PQQPPHPFSQQQQQQQQAHPHQFSQQQ--- 467
++ P+L L P++ + + +S +P P P P + Q PH Q +
Sbjct: 721 EESPLLPL-PEEPQLCPRSEGPHLSPRPEEPHLSPRP-EEPHLSPQAEEPHLSPQPEEPC 778
Query: 468 LQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQ 527
L ++ H Q P QP ++ H Q ++ L+ + ++ L Q
Sbjct: 779 LCAVPEEPHLSPQAEGPHLSPQP--------EELHL--SPQTEEPHLSPVPEEPCLSPQP 828
Query: 528 QQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQP-----PQQQQQQQP 582
++ + Q + + ++ S +P L + + + + PP++P P++ P
Sbjct: 829 EESHLSPQSEEPCLSPRPEE---SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP 885
Query: 583 PPSPQQHQLFGHDPAVEIPEE 603
P P L G +PA+ P E
Sbjct: 886 PGEPSLSPLLG-EPALSEPGE 905
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 110 bits (274), Expect = 9e-24
Identities = 91/226 (40%), Positives = 105/226 (46%), Gaps = 35/226 (15%)
Query: 395 TPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQ 454
TP+T + QQ QQQQQQ Q QQ LQQQQQQ QQQQ
Sbjct: 148 TPQTQLQLQQVALQQQQQQQ---QFQQQQQAALQQQQQQ-----------------QQQQ 187
Query: 455 QQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQL 514
Q QA QQ QQQ QQL + QQQ Q + H QQ Q+QQ Q Q Q++
Sbjct: 188 QFQAQQSAMQQQFQAVVQQQ----QQLQQQQQQQQHLIKLHHQNQQ--QIQQQQQQLQRI 241
Query: 515 AQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPP 574
AQLQ Q QQQQQQQ QQQ LQ QQ Q Q P SQAL Q+ Q
Sbjct: 242 AQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP-----SQALPQQL---QQM 293
Query: 575 QQQQQQQPPPSPQQHQLFGHDPAVEIPEEGFLLGCVFAIADYPEQM 620
Q QPPP PQQ + + P+ ++P + V P QM
Sbjct: 294 HHTQHHQPPPQPQQPPVAQNQPS-QLPPQSQTQPLVSQAQALPGQM 338
Score = 98.2 bits (243), Expect = 4e-20
Identities = 74/160 (46%), Positives = 81/160 (50%), Gaps = 27/160 (16%)
Query: 460 PHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQH--ALQQQFHQLQQHQLQQQQLAQL 517
PH + PQ QL Q + QQQ Q FQQQ ALQQQ Q QQ Q Q QQ A
Sbjct: 138 PHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ 197
Query: 518 QQQHSLLQQQQQQQIQQQQLQRM----HQ-----QQQQQQM-----------QSQTAPHL 557
QQ +++QQQQQ Q QQQQ Q + HQ QQQQQQ+ Q Q
Sbjct: 198 QQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQ 257
Query: 558 SQTSQALQHQVPPQQPPQQQQQQQPPPS---PQQHQLFGH 594
Q QALQ Q P QQPP QQ QPPPS PQQ Q H
Sbjct: 258 QQQQQALQAQPPIQQPP--MQQPQPPPSQALPQQLQQMHH 295
Score = 95.5 bits (236), Expect = 2e-19
Identities = 89/239 (37%), Positives = 110/239 (46%), Gaps = 23/239 (9%)
Query: 359 ILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQ--QQQHPV 416
++ T + T+ QQV QQ Q + + + QQQQQ QQQ Q Q
Sbjct: 143 VVSTATPQTQLQLQQVALQQQQQQQ-------QFQQQQQAALQQQQQQQQQQQFQAQQSA 195
Query: 417 LHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLH 476
+ Q Q ++Q QQQ QQQ QQ + + H +QQQ QQQQ + +Q QLQ QQ
Sbjct: 196 MQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQ-NQQQIQQQQQQLQRIAQLQLQQQQQ--- 251
Query: 477 PPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQ 536
QQ + QQQ Q Q Q +QQ Q Q Q QLQQ H Q Q Q QQ
Sbjct: 252 --QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHH--TQHHQPPPQPQQ 307
Query: 537 LQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQ-----QQQQQPPPSPQQHQ 590
Q Q QSQT P +SQ +QAL Q+ QPP + QQPP PQ Q
Sbjct: 308 PPVAQNQPSQLPPQSQTQPLVSQ-AQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
Score = 90.9 bits (224), Expect = 6e-18
Identities = 91/249 (36%), Positives = 110/249 (44%), Gaps = 27/249 (10%)
Query: 371 EQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPV-LHLQPQQIMQLQQ 429
+QQ QQ + + Q + + QQQ Q QQQQQQH + LH Q QQ +Q QQ
Sbjct: 179 QQQQQQQQQQFQAQQSAMQQQFQAVVQQ---QQQLQQQQQQQQHLIKLHHQNQQQIQQQQ 235
Query: 430 QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
QQ Q+I+Q Q QQQQQQ Q QQQ Q Q PP Q P QQ Q
Sbjct: 236 QQLQRIAQL-----------QLQQQQQQ----QQQQQQQQQQALQAQPPIQ-QPPMQQPQ 279
Query: 490 PFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQM 549
P Q AL QQ Q+ H Q Q QQ + Q Q Q Q Q Q + Q Q
Sbjct: 280 PPPSQ-ALPQQLQQM--HHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPG 336
Query: 550 QS-QTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEIPEEGFLLG 608
Q T P L + Q PP Q PQ QQQQ + Q Q+ P V++ E G
Sbjct: 337 QMLYTQPPLKFVRAPMVVQQPPVQ-PQVQQQQTAVQTAQAAQMVA--PGVQMITEALAQG 393
Query: 609 CVFAIADYP 617
+ A +P
Sbjct: 394 GMHIRARFP 402
Score = 72.8 bits (177), Expect = 2e-12
Identities = 84/282 (29%), Positives = 100/282 (35%), Gaps = 53/282 (18%)
Query: 361 QTLSAPTKNLEQQVNHSQQ----GHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPV 416
Q + + L+QQ Q H N + Q ++ + QQQQ QQQQQQ
Sbjct: 201 QAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ-- 258
Query: 417 LHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLH 476
Q QQ +Q Q QQ QQP P P QQ QQ HQ Q Q P Q
Sbjct: 259 ---QQQQALQAQPPIQQPPMQQPQP-PPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314
Query: 477 PPQQLHRPQQQLQPF-QQQHALQQQFHQLQ-----------------QHQLQQQQLAQLQ 518
P Q PQ Q QP Q AL Q Q Q Q+QQQQ A
Sbjct: 315 PSQL--PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQT 372
Query: 519 QQHSLLQQQQQQQIQQQQLQ-RMH---------------------QQQQQQQMQSQTAPH 556
Q + + Q I + Q MH +Q Q+ + P
Sbjct: 373 AQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPM 432
Query: 557 LSQTSQALQHQVPPQQPPQQQQQQQP-PPSPQQHQLFGHDPA 597
LS S Q Q P PP Q QP PS Q + PA
Sbjct: 433 LSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPA 474
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 110 bits (274), Expect = 9e-24
Identities = 91/226 (40%), Positives = 105/226 (46%), Gaps = 35/226 (15%)
Query: 395 TPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQ 454
TP+T + QQ QQQQQQ Q QQ LQQQQQQ QQQQ
Sbjct: 148 TPQTQLQLQQVALQQQQQQQ---QFQQQQQAALQQQQQQ-----------------QQQQ 187
Query: 455 QQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQL 514
Q QA QQ QQQ QQL + QQQ Q + H QQ Q+QQ Q Q Q++
Sbjct: 188 QFQAQQSAMQQQFQAVVQQQ----QQLQQQQQQQQHLIKLHHQNQQ--QIQQQQQQLQRI 241
Query: 515 AQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPP 574
AQLQ Q QQQQQQQ QQQ LQ QQ Q Q P SQAL Q+ Q
Sbjct: 242 AQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP-----SQALPQQL---QQM 293
Query: 575 QQQQQQQPPPSPQQHQLFGHDPAVEIPEEGFLLGCVFAIADYPEQM 620
Q QPPP PQQ + + P+ ++P + V P QM
Sbjct: 294 HHTQHHQPPPQPQQPPVAQNQPS-QLPPQSQTQPLVSQAQALPGQM 338
Score = 98.2 bits (243), Expect = 4e-20
Identities = 74/160 (46%), Positives = 81/160 (50%), Gaps = 27/160 (16%)
Query: 460 PHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQH--ALQQQFHQLQQHQLQQQQLAQL 517
PH + PQ QL Q + QQQ Q FQQQ ALQQQ Q QQ Q Q QQ A
Sbjct: 138 PHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQ 197
Query: 518 QQQHSLLQQQQQQQIQQQQLQRM----HQ-----QQQQQQM-----------QSQTAPHL 557
QQ +++QQQQQ Q QQQQ Q + HQ QQQQQQ+ Q Q
Sbjct: 198 QQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQ 257
Query: 558 SQTSQALQHQVPPQQPPQQQQQQQPPPS---PQQHQLFGH 594
Q QALQ Q P QQPP QQ QPPPS PQQ Q H
Sbjct: 258 QQQQQALQAQPPIQQPP--MQQPQPPPSQALPQQLQQMHH 295
Score = 95.5 bits (236), Expect = 2e-19
Identities = 89/239 (37%), Positives = 110/239 (46%), Gaps = 23/239 (9%)
Query: 359 ILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQ--QQQHPV 416
++ T + T+ QQV QQ Q + + + QQQQQ QQQ Q Q
Sbjct: 143 VVSTATPQTQLQLQQVALQQQQQQQ-------QFQQQQQAALQQQQQQQQQQQFQAQQSA 195
Query: 417 LHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLH 476
+ Q Q ++Q QQQ QQQ QQ + + H +QQQ QQQQ + +Q QLQ QQ
Sbjct: 196 MQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQ-NQQQIQQQQQQLQRIAQLQLQQQQQ--- 251
Query: 477 PPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQ 536
QQ + QQQ Q Q Q +QQ Q Q Q QLQQ H Q Q Q QQ
Sbjct: 252 --QQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHH--TQHHQPPPQPQQ 307
Query: 537 LQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQ-----QQQQQPPPSPQQHQ 590
Q Q QSQT P +SQ +QAL Q+ QPP + QQPP PQ Q
Sbjct: 308 PPVAQNQPSQLPPQSQTQPLVSQ-AQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365
Score = 88.6 bits (218), Expect = 3e-17
Identities = 87/234 (37%), Positives = 105/234 (44%), Gaps = 27/234 (11%)
Query: 371 EQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPV-LHLQPQQIMQLQQ 429
+QQ QQ + + Q + + QQQ Q QQQQQQH + LH Q QQ +Q QQ
Sbjct: 179 QQQQQQQQQQFQAQQSAMQQQFQAVVQQ---QQQLQQQQQQQQHLIKLHHQNQQQIQQQQ 235
Query: 430 QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
QQ Q+I+Q Q QQQQQQ Q QQQ Q Q PP Q P QQ Q
Sbjct: 236 QQLQRIAQL-----------QLQQQQQQ----QQQQQQQQQQALQAQPPIQ-QPPMQQPQ 279
Query: 490 PFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQM 549
P Q AL QQ Q+ H Q Q QQ + Q Q Q Q Q Q + Q Q
Sbjct: 280 PPPSQ-ALPQQLQQM--HHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPG 336
Query: 550 QS-QTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEIPE 602
Q T P L + Q PP Q PQ QQQQ + Q Q+ P V++ +
Sbjct: 337 QMLYTQPPLKFVRAPMVVQQPPVQ-PQVQQQQTAVQTAQAAQMVA--PGVQVSQ 387
Score = 87.8 bits (216), Expect = 5e-17
Identities = 89/260 (34%), Positives = 101/260 (38%), Gaps = 34/260 (13%)
Query: 370 LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPV-LHLQPQQIMQLQ 428
L+QQ QQ A Q Q QQQ QQQQH + LH Q QQ +Q Q
Sbjct: 177 LQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQ--QQQQHLIKLHHQNQQQIQQQ 234
Query: 429 QQQQQQISQQPYPQQPPHPFSQQQQQQQ--QAHP--HQFSQQQLQFPQQQLHPP--QQLH 482
QQQ Q+I+Q QQ QQQQQQQ QA P Q QQ Q P Q P QQ+H
Sbjct: 235 QQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMH 294
Query: 483 RPQQQLQPFQQQH--ALQQQFHQLQQHQLQQQQLAQLQ---------------------- 518
Q P Q Q Q Q QL Q ++Q Q
Sbjct: 295 HTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVV 354
Query: 519 QQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQ 578
QQ + Q QQQQ Q Q Q+ + P LS S Q Q P PP Q
Sbjct: 355 QQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQP 414
Query: 579 QQQP-PPSPQQHQLFGHDPA 597
QP PS Q + PA
Sbjct: 415 SPQPGQPSSQPNSNVSSGPA 434
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 109 bits (272), Expect = 2e-23
Identities = 76/241 (31%), Positives = 119/241 (49%), Gaps = 22/241 (9%)
Query: 835 KQNEVANVQPSS-KRARIEDVPP--PTK-----KLTPELT-PFVLFTGFEPVQVQQYIKK 885
K+ +V +P KR + E+ P P++ KL E T P VLFTG + ++ +
Sbjct: 1852 KEEDVVTPKPGKRKRDQAEEEPNRIPSRSLRRTKLNQESTAPKVLFTGVVDARGERAV-- 1909
Query: 886 LYILGGEVAESAQKCTHLIASKVTRTVKFLTAISVVKHIVTPEWLEECFRCQKFIDEQNY 945
LGG +A SA + +HL+ ++ RTVKFL A+ I++ +WL + + F+ Y
Sbjct: 1910 -LALGGSLAGSAAEASHLVTDRIRRTVKFLCALGRGIPILSLDWLHQSRKAGFFLPPDEY 1968
Query: 946 ILRDAEAEVLFSFSLEESLKRAHVSPLFKAKYFYITPGICPSLSTMKAIVECAGGKVLSK 1005
++ D E E F FSL+++L RA L + Y+TPG+ P M I+ C GG L
Sbjct: 1969 VVTDPEQEKNFGFSLQDALSRARERRLLEGYEIYVTPGVQPPPPQMGEIISCCGGTYLPS 2028
Query: 1006 QPSFRKLMEHKQNSSLSEIILISCENDLHLCREYFARGIDVHNAEFVLTGVLTQTLDYES 1065
P S + ++I+C D C G+ + + EF+LTGVL Q E+
Sbjct: 2029 MP----------RSYKPQRVVITCPQDFPHCSIPLRVGLPLLSPEFLLTGVLKQEAKPEA 2078
Query: 1066 Y 1066
+
Sbjct: 2079 F 2079
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 98.6 bits (244), Expect = 3e-20
Identities = 86/248 (34%), Positives = 106/248 (42%), Gaps = 29/248 (11%)
Query: 376 HSQQGHTNANAVLFSQVK--VTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQ 433
+S Q + +VL SQ K + T QQQQQ QQQQQQ Q QQ Q QQQQQ
Sbjct: 563 NSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQS 622
Query: 434 QISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHR--PQQQL--- 488
IS Q QQ +QQQQQQQQ Q QQQ Q QQQ P Q + P Q L
Sbjct: 623 SISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRS 682
Query: 489 -QPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQ--------------------- 526
P QQ+ LQQ +Q Q Q Q QHS++ Q
Sbjct: 683 PLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYM 742
Query: 527 QQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSP 586
QQ + QQL Q Q+Q M+ + L Q A ++ PQ + + PP
Sbjct: 743 NSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYK 802
Query: 587 QQHQLFGH 594
Q + G+
Sbjct: 803 DQRRNVGN 810
Score = 93.6 bits (231), Expect = 9e-19
Identities = 70/180 (38%), Positives = 85/180 (47%), Gaps = 16/180 (8%)
Query: 427 LQQQQQQQISQQ----PYPQQPPHPFS----------QQQQQQQQAHPHQFSQQQLQFPQ 472
L QQ+ Q +S+ P+P P + Q QQ P Q L + Q
Sbjct: 529 LMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQ 588
Query: 473 QQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQI 532
QQ QQ + QQQ Q QQQ QQQ Q QQ + QQ Q Q S QQQQQQQ
Sbjct: 589 QQQQQQQQQQQQQQQQQQQQQQQQQQQQ-QQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647
Query: 533 QQQQLQRMHQQQQQQQMQSQTAPHLSQTSQ-ALQHQVPPQQPPQQQQQQQPPPSPQQHQL 591
QQQQ Q+ QQQQQQQ Q + P S SQ L+ +P QQ QQ Q P + +Q+
Sbjct: 648 QQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQV 707
Score = 82.4 bits (202), Expect = 2e-15
Identities = 79/269 (29%), Positives = 98/269 (36%), Gaps = 52/269 (19%)
Query: 372 QQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQP--------QQ 423
Q+V+H+QQ Q+ + H QQ Q Q Q L Q+
Sbjct: 428 QEVSHAQQ---------LKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQE 478
Query: 424 IMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQ-------------------QQAHPHQFS 464
+ QQ S Q P S Q + Q P S
Sbjct: 479 KIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLS 538
Query: 465 QQQLQFPQQQLHPPQ------------QLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQ 512
+ + P + P Q Q ++ + P Q + +L Q QQ Q QQQ
Sbjct: 539 RSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQ 598
Query: 513 QLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQ 572
Q Q QQQ QQQQQQQ QQQQ Q+ QQQQ Q + Q Q Q Q QQ
Sbjct: 599 QQQQQQQQ----QQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQ 654
Query: 573 PPQQQQQQQPPPSPQQHQLFGHDPAVEIP 601
QQQQQQQ PS Q Q P + P
Sbjct: 655 QQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683
Score = 62.8 bits (151), Expect = 2e-09
Identities = 73/258 (28%), Positives = 99/258 (38%), Gaps = 33/258 (12%)
Query: 347 IQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQ 406
+ N+PS + + Q + +QQ QQ Q + + QQQQ
Sbjct: 575 LPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQS 634
Query: 407 AQQQQQQHPVLHLQPQQIMQLQQQQQQQISQ------QPYPQQP----PHPFSQQ---QQ 453
+ QQQ Q QQ Q QQQQQQQ Q Q P QP P P Q+ QQ
Sbjct: 635 SISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQ 694
Query: 454 QQQQ---AHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQ 510
Q Q +Q SQQQ Q Q Q P P + + QQ L
Sbjct: 695 MQNQPIAGMGYQVSQQQ---RQDQHSVVGQNTGPSPSPNPCSNPNT-GSGYMNSQQSLLN 750
Query: 511 QQQLAQLQQ-QHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVP 569
QQ + + Q Q +++Q+QQ +QQQ L + Q Q+ HLS+ P
Sbjct: 751 QQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINR----HLSRP--------P 798
Query: 570 PQQPPQQQQQQQPPPSPQ 587
P Q++ P+ Q
Sbjct: 799 PDYKDQRRNVGNMQPTAQ 816
Score = 35.0 bits (79), Expect = 0.38
Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 1/101 (0%)
Query: 428 QQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ 487
+QQ+ + +P P ++ Q QQ QFSQ+ + P QL P Q+ Q
Sbjct: 974 KQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVA-PPNQLTPAVQMRPMNQM 1032
Query: 488 LQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQ 528
Q Q + L+ +QL Q L L Q + L Q +
Sbjct: 1033 SQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSR 1073
Score = 33.1 bits (74), Expect = 1.4
Identities = 30/105 (28%), Positives = 40/105 (38%), Gaps = 16/105 (15%)
Query: 484 PQQQLQPFQQQHALQQQFHQLQQ--HQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMH 541
PQ Q QP Q + Q+ H Q +Q+A +QQH+ +QQ QQQ H
Sbjct: 408 PQSQAQP-QTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQ----------H 456
Query: 542 QQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSP 586
Q + S P Q ++P QQ Q P P
Sbjct: 457 QPTNWSALPSSAGPSPGPFG---QEKIPSPSFGQQTFSPQSSPMP 498
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 98.2 bits (243), Expect = 4e-20
Identities = 77/181 (42%), Positives = 88/181 (48%), Gaps = 23/181 (12%)
Query: 416 VLHLQPQQIMQLQQQQ--QQQISQQPYP-----QQPPH-PFSQQQQQQQQAHPHQFSQQQ 467
+LHLQ QQ +Q +Q QQQ S P Q+P P S Q P QQ
Sbjct: 49 LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITP----QQM 104
Query: 468 LQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQ 527
Q QQQ+ PQQL QQ Q Q Q+F++ QQ QL Q L Q QQQ QQQ
Sbjct: 105 QQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQ 164
Query: 528 QQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQ 587
QQQQ QQQQ Q+ QQQQQQQ Q Q QH + QQQQQQQ + Q
Sbjct: 165 QQQQQQQQQQQQQQQQQQQQQQQQQQ-----------QHPGKQAKEQQQQQQQQQQLAAQ 213
Query: 588 Q 588
Q
Sbjct: 214 Q 214
Score = 90.5 bits (223), Expect = 8e-18
Identities = 79/190 (41%), Positives = 91/190 (47%), Gaps = 25/190 (13%)
Query: 390 SQVKVTPETHMLQQQQQAQQQQ----QQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPP 445
S +TP+ QQ QQ QQQ QQ L LQ QQ + LQQQQ Q+ ++ Q
Sbjct: 90 SVAMMTPQVITPQQMQQILQQQVLSPQQLQAL-LQQQQAVMLQQQQLQEFYKKQQEQLHL 148
Query: 446 HPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQ 505
QQQQQQQQ QQQ Q QQQ QQ + QQQ Q QQQH +Q Q Q
Sbjct: 149 QLLQQQQQQQQQ------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQ-Q 201
Query: 506 QHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQ 565
Q Q QQQQLA QQ + QQQL +M Q QQQQ + S L Q
Sbjct: 202 QQQQQQQQLA------------AQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPG-Q 248
Query: 566 HQVPPQQPPQ 575
+P Q PQ
Sbjct: 249 AALPVQSLPQ 258
Score = 88.6 bits (218), Expect = 3e-17
Identities = 83/202 (41%), Positives = 100/202 (49%), Gaps = 28/202 (13%)
Query: 370 LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQ 429
L+QQV QQ A+L Q V MLQQQQ + ++Q LHLQ ++Q QQ
Sbjct: 108 LQQQVLSPQQ----LQALLQQQQAV-----MLQQQQLQEFYKKQQEQLHLQ---LLQQQQ 155
Query: 430 QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
QQQQQ QQ QQ QQQQQQQQ Q QQQ Q QQQ HP +Q QQQ Q
Sbjct: 156 QQQQQQQQQQQQQQ------QQQQQQQQ----QQQQQQQQQQQQQQHPGKQAKEQQQQQQ 205
Query: 490 PFQQQHALQQQFHQ--LQQHQLQQQQ-LAQLQQQHSLLQQQQQQQIQQQQLQR--MHQQQ 544
QQ A Q F Q LQ QLQQQQ L LQ+Q + Q + Q L + + +
Sbjct: 206 QQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 265
Query: 545 QQQQMQSQTAPHLSQTSQALQH 566
QQ + T H S ++H
Sbjct: 266 IQQLWKEVTGVH-SMEDNGIKH 286
Score = 71.2 bits (173), Expect = 5e-12
Identities = 79/262 (30%), Positives = 107/262 (40%), Gaps = 41/262 (15%)
Query: 348 QQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQA 407
QQ+ P + +LQ A L+QQ Q+ + L Q+ + QQQQQ
Sbjct: 110 QQVLSPQQLQALLQQQQAVM--LQQQ--QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 165
Query: 408 QQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQ-QQQQQQQAHPHQFSQQ 466
QQQQQQ Q QQQQQQQ QQ QQ HP Q ++QQQQQ Q + Q
Sbjct: 166 QQQQQQ------------QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 213
Query: 467 QLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQL-----QQHQLQQQQLAQLQQQH 521
QL F QQ L QQLQ QQQH L Q L Q L Q L Q
Sbjct: 214 QLVFQQQLLQ--------MQQLQ--QQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 263
Query: 522 SLLQQQQQQ-----QIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQ 576
+ +QQ ++ ++ ++ S T+ + S+ S + H
Sbjct: 264 AEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSV 323
Query: 577 QQQQQPPPSPQQ----HQLFGH 594
++ S ++ H L+GH
Sbjct: 324 LSARRDSSSHEETGASHTLYGH 345
Score = 61.6 bits (148), Expect = 4e-09
Identities = 51/153 (33%), Positives = 58/153 (37%), Gaps = 49/153 (32%)
Query: 487 QLQPFQQQHALQ-------------------------------------QQFHQLQQHQL 509
+L QQQ ALQ Q Q Q+
Sbjct: 48 ELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQI 107
Query: 510 QQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMH------------QQQQQQQMQSQTAPHL 557
QQQ+ QQ +LLQQQQ +QQQQLQ + QQQQQQQ Q Q
Sbjct: 108 LQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 167
Query: 558 SQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQ 590
Q Q Q Q QQ QQQQQQQ P + Q
Sbjct: 168 QQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQ 200
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 94.4 bits (233), Expect = 5e-19
Identities = 75/202 (37%), Positives = 89/202 (44%), Gaps = 40/202 (19%)
Query: 416 VLHLQPQQIMQLQQQQ--QQQIS--QQPYPQQPPHPFSQQQQQQQ---------QAHPHQ 462
+LHLQ QQ +Q +Q QQQ S + P P + + + HPH
Sbjct: 49 LLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHN 108
Query: 463 F----------------SQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQ 506
QQ Q QQQ+ PQQL QQ Q Q Q+F++ QQ
Sbjct: 109 TFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQ 168
Query: 507 HQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQH 566
QL Q L Q QQQ QQQQQQQ QQQQ Q+ QQQQQQQ Q Q QH
Sbjct: 169 EQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----------QH 217
Query: 567 QVPPQQPPQQQQQQQPPPSPQQ 588
+ QQQQQQQ + QQ
Sbjct: 218 PGKQAKEQQQQQQQQQQLAAQQ 239
Score = 94.4 bits (233), Expect = 5e-19
Identities = 85/204 (41%), Positives = 97/204 (47%), Gaps = 26/204 (12%)
Query: 377 SQQGHT-NANAVLFSQVKVTPETHMLQQQQQAQQQQ----QQHPVLHLQPQQIMQLQQQQ 431
S GH N AV S +TP+ QQ QQ QQQ QQ L LQ QQ + LQQQQ
Sbjct: 101 SGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQAL-LQQQQAVMLQQQQ 159
Query: 432 QQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPF 491
Q+ ++ Q QQQQQQQQ QQQ Q QQQ QQ + QQQ Q
Sbjct: 160 LQEFYKKQQEQLHLQLLQQQQQQQQQ------QQQQQQQQQQQQQQQQQQQQQQQQQQQQ 213
Query: 492 QQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQS 551
QQQH +Q Q QQ Q QQQQLA QQ + QQQL +M Q QQQQ + S
Sbjct: 214 QQQHPGKQAKEQ-QQQQQQQQQLA------------AQQLVFQQQLLQMQQLQQQQHLLS 260
Query: 552 QTAPHLSQTSQALQHQVPPQQPPQ 575
L Q +P Q PQ
Sbjct: 261 LQRQGLISIPPG-QAALPVQSLPQ 283
Score = 90.5 bits (223), Expect = 8e-18
Identities = 118/382 (30%), Positives = 156/382 (40%), Gaps = 82/382 (21%)
Query: 194 EEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSS 253
+E E + N + QN ST A S++G SGD +++E S EL+
Sbjct: 3 QESATETISNSSMN-QNGMSTLSSQLDAGSRDGRSSGD------TSSEVSTVELLHLQQQ 55
Query: 254 DSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVR---- 309
+ L AA++ L Q + GL + ++ P L PE +
Sbjct: 56 QA------------------LQAARQLLLQQQTSGLKSPKSSDKQRPLQELLPETKLCIC 97
Query: 310 GNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKN 369
G+ G + +A +P V T P + ILQ
Sbjct: 98 GHSSGDGHPHNTFAVPVSVAMMTPQVIT---------------PQQMQQILQ-------- 134
Query: 370 LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQ 429
QQV QQ A+L Q V MLQQQQ + ++Q LHL Q++Q QQ
Sbjct: 135 --QQVLSPQQ----LQALLQQQQAV-----MLQQQQLQEFYKKQQEQLHL---QLLQQQQ 180
Query: 430 QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
QQQQQ QQ QQQQQQQQ Q QQQ Q QQQ HP +Q QQQ Q
Sbjct: 181 QQQQQQQQQ----------QQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQ 230
Query: 490 PFQQQHALQQQFHQ--LQQHQLQQQQ-LAQLQQQHSLLQQQQQQQIQQQQLQR--MHQQQ 544
QQ A Q F Q LQ QLQQQQ L LQ+Q + Q + Q L + + +
Sbjct: 231 QQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 290
Query: 545 QQQQMQSQTAPHLSQTSQALQH 566
QQ + T H S ++H
Sbjct: 291 IQQLWKEVTGVH-SMEDNGIKH 311
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 93.2 bits (230), Expect = 1e-18
Identities = 79/229 (34%), Positives = 92/229 (40%), Gaps = 10/229 (4%)
Query: 377 SQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHP---------VLHLQPQQIMQL 427
+ QG+T + + Q P M+ +Q Q HP HLQ + +
Sbjct: 1940 TSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYV 1999
Query: 428 QQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ 487
QQ Q+ H QQ P Q + P QQ + QQQ
Sbjct: 2000 HQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQ 2059
Query: 488 LQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQ 547
Q QQQ QQQ Q Q H QQQQ L+QQ QQQQQQQ QQQQ Q+ QQQ QQ
Sbjct: 2060 QQQQQQQQQQQQQ-QQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQ 2118
Query: 548 QMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDP 596
Q Q Q AP Q Q Q Q QQQQQ Q QL P
Sbjct: 2119 QQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQP 2167
Score = 91.3 bits (225), Expect = 4e-18
Identities = 81/207 (39%), Positives = 98/207 (47%), Gaps = 32/207 (15%)
Query: 362 TLSAPTKNLEQQVN---HSQQ---GHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHP 415
TL PT++L+Q+ + H Q GH + FS + +T M+ Q Q
Sbjct: 1983 TLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSH-QTLQQTPMISTMTPMSAQGVQAG 2041
Query: 416 VLH--LQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQ 473
V + P+Q Q QQQQQQQ QQ QQQQQQQ + QQQ QQ
Sbjct: 2042 VRSTAILPEQQQQQQQQQQQQQQQQ------------QQQQQQQQQQYHIRQQQ----QQ 2085
Query: 474 QLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQ 533
Q+ QQ + QQQ Q QQQ QQQ Q QQHQ QQQQ A Q Q Q Q Q Q
Sbjct: 2086 QILRQQQQQQQQQQQQQQQQQ---QQQQQQQQQHQQQQQQQAAPPQP----QPQSQPQFQ 2138
Query: 534 QQQLQRMHQQQQQQQMQSQTAPHLSQT 560
+Q LQ+ QQQQ + Q LS T
Sbjct: 2139 RQGLQQTQQQQQTAALVRQLQQQLSNT 2165
Score = 85.5 bits (210), Expect = 2e-16
Identities = 69/144 (47%), Positives = 74/144 (51%), Gaps = 22/144 (15%)
Query: 394 VTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQ 453
+ PE QQQQQ QQQQQQ Q QQ ++QQQQQQI +Q QQQQ
Sbjct: 2047 ILPEQQQQQQQQQQQQQQQQQQQQQQQQQQY-HIRQQQQQQILRQ-----------QQQQ 2094
Query: 454 QQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQ--LQQHQLQQ 511
QQQQ Q QQQ Q QQQ H QQ QQQ P Q Q Q QF + LQQ Q QQ
Sbjct: 2095 QQQQQQQQQ-QQQQQQQQQQQQHQQQQ----QQQAAPPQPQPQSQPQFQRQGLQQTQQQQ 2149
Query: 512 QQLA---QLQQQHSLLQQQQQQQI 532
Q A QLQQQ S Q Q I
Sbjct: 2150 QTAALVRQLQQQLSNTQPQPSTNI 2173
Score = 73.9 bits (180), Expect = 7e-13
Identities = 73/233 (31%), Positives = 86/233 (36%), Gaps = 57/233 (24%)
Query: 411 QQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHP-FSQQQQQQQQAHPHQFSQQQLQ 469
+QQ P + Q Q++ Q QQ Q + Q Q P + Q Q + QQ
Sbjct: 1899 RQQQPAVP-QGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHT 1957
Query: 470 FPQQQLHPPQQLHRPQQQLQP------------FQQQ-------------HAL---QQQF 501
P + PP +P Q P QQ+ H L Q+
Sbjct: 1958 GPAGTMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFS 2017
Query: 502 HQLQQHQ-----------------------LQQQQLAQLQQQHSLLQQQQQQQIQQQQLQ 538
HQ Q L +QQ Q QQQ QQQQQQQ QQQQ
Sbjct: 2018 HQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQY 2077
Query: 539 RMHQQQQQ----QQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQ 587
+ QQQQQ QQ Q Q Q Q Q Q QQ QQQQQQ PP PQ
Sbjct: 2078 HIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQ 2130
Score = 61.2 bits (147), Expect = 5e-09
Identities = 55/163 (33%), Positives = 70/163 (42%), Gaps = 17/163 (10%)
Query: 336 RTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVT 395
+TL+ + + M+ A + T P + +QQ QQ Q +
Sbjct: 2019 QTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQ----QQQQQQ 2074
Query: 396 PETHMLQQQQQA----QQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQ 451
+ H+ QQQQQ QQQQQQ Q QQ Q QQQQQ Q QQ PP P
Sbjct: 2075 QQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQ-QQQQQQAAPPQP---- 2129
Query: 452 QQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQ 494
Q Q+ P QF +Q LQ QQQ + + QQQL Q Q
Sbjct: 2130 ---QPQSQP-QFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQ 2168
Score = 30.8 bits (68), Expect = 7.1
Identities = 32/105 (30%), Positives = 40/105 (38%), Gaps = 14/105 (13%)
Query: 348 QQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQA 407
QQ + HI Q +QQ QQ Q + + H QQQQQA
Sbjct: 2068 QQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQ---QQQQQQQQQHQQQQQQQA 2124
Query: 408 ---------QQQQQQHPVLHL-QPQQIMQLQQQQQQQISQ-QPYP 441
Q Q Q+ + Q QQ L +Q QQQ+S QP P
Sbjct: 2125 APPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQP 2169
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 91.3 bits (225), Expect = 4e-18
Identities = 107/393 (27%), Positives = 147/393 (37%), Gaps = 67/393 (17%)
Query: 208 SQNEGSTDEKSSPASSQEGSP-SGDQQFSPKSNTEKSKGELMFDDSS------DSSPEKQ 260
S NE DE + + +P SG + +PK +K E S+ D+ +
Sbjct: 210 SINEEDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIK 269
Query: 261 ERNLNWTPAEVPQLAAA-------------KRRLPQGKEPGLINLCANVPPVPGNILPPE 307
+N N T EV ++ A+ KR+ K+ L L A +
Sbjct: 270 GQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAES 329
Query: 308 VRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPT 367
+ + Q +S + + ++ + Q + P ++A T+ P
Sbjct: 330 AEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPM 389
Query: 368 KNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQL 427
+ V + +N A L S + T Q Q QQH Q +Q
Sbjct: 390 NQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQH-------QMQLQQ 442
Query: 428 QQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ 487
QQQQQQQ QQ QQQQ QQ HQ QQQ+Q QQ
Sbjct: 443 QQQQQQQQMQQ-----------MQQQQLQQHQMHQQIQQQMQ---------------QQH 476
Query: 488 LQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQ 547
Q QQH QQQ H Q Q+ QQQ LQQQ QQ++Q QQLQ H Q Q Q
Sbjct: 477 FQHHMQQHLQQQQQH--LQQQINQQQ----------LQQQLQQRLQLQQLQ--HMQHQSQ 522
Query: 548 QMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQ 580
Q +P SQ + + PQ QQ Q Q
Sbjct: 523 PSPRQHSPVASQITSPIPAIGSPQPASQQHQSQ 555
Score = 80.1 bits (196), Expect = 1e-14
Identities = 57/137 (41%), Positives = 72/137 (52%), Gaps = 18/137 (13%)
Query: 471 PQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQ 530
P Q+ P Q + Q QLQ QQQ QQQ Q+QQ QLQQ Q+ H +QQQ QQ
Sbjct: 423 PSTQVSPSVQTQQHQMQLQ--QQQQQQQQQMQQMQQQQLQQHQM------HQQIQQQMQQ 474
Query: 531 QIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQH- 589
Q Q +Q+ H QQQQQ +Q Q + Q Q LQ ++ QQ Q Q QP SP+QH
Sbjct: 475 QHFQHHMQQ-HLQQQQQHLQQQI--NQQQLQQQLQQRLQLQQLQHMQHQSQP--SPRQHS 529
Query: 590 ----QLFGHDPAVEIPE 602
Q+ PA+ P+
Sbjct: 530 PVASQITSPIPAIGSPQ 546
Score = 77.4 bits (189), Expect = 7e-14
Identities = 55/132 (41%), Positives = 63/132 (47%), Gaps = 15/132 (11%)
Query: 462 QFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQH 521
Q Q QLQ QQQ QQQ+Q QQQ Q Q HQ Q Q+QQQ QQH
Sbjct: 434 QQHQMQLQQQQQQ---------QQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQH 484
Query: 522 SLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPP---QQPPQQQQ 578
QQQQQ +QQQ Q+ QQQ QQ++Q Q H+ SQ Q P Q
Sbjct: 485 ---LQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPA 541
Query: 579 QQQPPPSPQQHQ 590
P P+ QQHQ
Sbjct: 542 IGSPQPASQQHQ 553
Score = 31.6 bits (70), Expect = 4.2
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
Query: 551 SQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEIPEE 603
S + +S + Q QHQ+ QQ QQQQQQ QQ QL H +I ++
Sbjct: 421 SAPSTQVSPSVQTQQHQMQLQQQQQQQQQQM--QQMQQQQLQQHQMHQQIQQQ 471
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 91.3 bits (225), Expect = 4e-18
Identities = 107/393 (27%), Positives = 147/393 (37%), Gaps = 67/393 (17%)
Query: 208 SQNEGSTDEKSSPASSQEGSP-SGDQQFSPKSNTEKSKGELMFDDSS------DSSPEKQ 260
S NE DE + + +P SG + +PK +K E S+ D+ +
Sbjct: 215 SINEEDADEANRAIGEKRAAPDSGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIK 274
Query: 261 ERNLNWTPAEVPQLAAA-------------KRRLPQGKEPGLINLCANVPPVPGNILPPE 307
+N N T EV ++ A+ KR+ K+ L L A +
Sbjct: 275 GQNPNATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYRASLVSKAAAES 334
Query: 308 VRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPT 367
+ + Q +S + + ++ + Q + P ++A T+ P
Sbjct: 335 AEAQTIRSVQQTLASTNLTSSLLLNTPLSQHGTVSASPQTLQQSLPRSIAPKPLTMRLPM 394
Query: 368 KNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQL 427
+ V + +N A L S + T Q Q QQH Q +Q
Sbjct: 395 NQIVTSVTIAANMPSNIGAPLISSMGTTMVGSAPSTQVSPSVQTQQH-------QMQLQQ 447
Query: 428 QQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ 487
QQQQQQQ QQ QQQQ QQ HQ QQQ+Q QQ
Sbjct: 448 QQQQQQQQMQQ-----------MQQQQLQQHQMHQQIQQQMQ---------------QQH 481
Query: 488 LQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQ 547
Q QQH QQQ H Q Q+ QQQ LQQQ QQ++Q QQLQ H Q Q Q
Sbjct: 482 FQHHMQQHLQQQQQH--LQQQINQQQ----------LQQQLQQRLQLQQLQ--HMQHQSQ 527
Query: 548 QMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQ 580
Q +P SQ + + PQ QQ Q Q
Sbjct: 528 PSPRQHSPVASQITSPIPAIGSPQPASQQHQSQ 560
Score = 80.1 bits (196), Expect = 1e-14
Identities = 57/137 (41%), Positives = 72/137 (52%), Gaps = 18/137 (13%)
Query: 471 PQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQ 530
P Q+ P Q + Q QLQ QQQ QQQ Q+QQ QLQQ Q+ H +QQQ QQ
Sbjct: 428 PSTQVSPSVQTQQHQMQLQ--QQQQQQQQQMQQMQQQQLQQHQM------HQQIQQQMQQ 479
Query: 531 QIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQH- 589
Q Q +Q+ H QQQQQ +Q Q + Q Q LQ ++ QQ Q Q QP SP+QH
Sbjct: 480 QHFQHHMQQ-HLQQQQQHLQQQI--NQQQLQQQLQQRLQLQQLQHMQHQSQP--SPRQHS 534
Query: 590 ----QLFGHDPAVEIPE 602
Q+ PA+ P+
Sbjct: 535 PVASQITSPIPAIGSPQ 551
Score = 77.4 bits (189), Expect = 7e-14
Identities = 55/132 (41%), Positives = 63/132 (47%), Gaps = 15/132 (11%)
Query: 462 QFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQH 521
Q Q QLQ QQQ QQQ+Q QQQ Q Q HQ Q Q+QQQ QQH
Sbjct: 439 QQHQMQLQQQQQQ---------QQQQMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQH 489
Query: 522 SLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPP---QQPPQQQQ 578
QQQQQ +QQQ Q+ QQQ QQ++Q Q H+ SQ Q P Q
Sbjct: 490 ---LQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPA 546
Query: 579 QQQPPPSPQQHQ 590
P P+ QQHQ
Sbjct: 547 IGSPQPASQQHQ 558
Score = 31.6 bits (70), Expect = 4.2
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
Query: 551 SQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEIPEE 603
S + +S + Q QHQ+ QQ QQQQQQ QQ QL H +I ++
Sbjct: 426 SAPSTQVSPSVQTQQHQMQLQQQQQQQQQQM--QQMQQQQLQQHQMHQQIQQQ 476
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 90.1 bits (222), Expect = 1e-17
Identities = 78/186 (41%), Positives = 90/186 (48%), Gaps = 25/186 (13%)
Query: 394 VTPETHMLQQQQQAQQQQ----QQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFS 449
+TP+ QQ QQ QQQ QQ L LQ QQ + LQQQQ Q+ ++ Q
Sbjct: 2 MTPQVITPQQMQQILQQQVLSPQQLQAL-LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQ 60
Query: 450 QQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQL 509
QQQQQQQQ QQQ Q QQQ QQ + QQQ Q QQQH +Q Q QQ Q
Sbjct: 61 QQQQQQQQ------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQ-QQQQQ 113
Query: 510 QQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVP 569
QQQQLA QQ + QQQL +M Q QQQQ + S L Q +P
Sbjct: 114 QQQQLA------------AQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPG-QAALP 160
Query: 570 PQQPPQ 575
Q PQ
Sbjct: 161 VQSLPQ 166
Score = 89.4 bits (220), Expect = 2e-17
Identities = 58/124 (46%), Positives = 65/124 (52%), Gaps = 11/124 (8%)
Query: 465 QQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLL 524
QQ Q QQQ+ PQQL QQ Q Q Q+F++ QQ QL Q L Q QQQ
Sbjct: 10 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 69
Query: 525 QQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPP 584
QQQQQQQ QQQQ Q+ QQQQQQQ Q Q QH + QQQQQQQ
Sbjct: 70 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----------QHPGKQAKEQQQQQQQQQQL 118
Query: 585 SPQQ 588
+ QQ
Sbjct: 119 AAQQ 122
Score = 88.6 bits (218), Expect = 3e-17
Identities = 83/202 (41%), Positives = 100/202 (49%), Gaps = 28/202 (13%)
Query: 370 LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQ 429
L+QQV QQ A+L Q V MLQQQQ + ++Q LHLQ ++Q QQ
Sbjct: 16 LQQQVLSPQQ----LQALLQQQQAV-----MLQQQQLQEFYKKQQEQLHLQ---LLQQQQ 63
Query: 430 QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
QQQQQ QQ QQ QQQQQQQQ Q QQQ Q QQQ HP +Q QQQ Q
Sbjct: 64 QQQQQQQQQQQQQQ------QQQQQQQQ----QQQQQQQQQQQQQQHPGKQAKEQQQQQQ 113
Query: 490 PFQQQHALQQQFHQ--LQQHQLQQQQ-LAQLQQQHSLLQQQQQQQIQQQQLQR--MHQQQ 544
QQ A Q F Q LQ QLQQQQ L LQ+Q + Q + Q L + + +
Sbjct: 114 QQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 173
Query: 545 QQQQMQSQTAPHLSQTSQALQH 566
QQ + T H S ++H
Sbjct: 174 IQQLWKEVTGVH-SMEDNGIKH 194
Score = 75.1 bits (183), Expect = 3e-13
Identities = 49/107 (45%), Positives = 57/107 (53%), Gaps = 4/107 (3%)
Query: 486 QQLQPFQQQHALQQQFHQLQQHQ--LQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQ 543
Q + P Q Q LQQQ QQ Q LQQQQ LQQQ LQ+ ++Q +Q LQ + QQ
Sbjct: 5 QVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQ--LQEFYKKQQEQLHLQLLQQQ 62
Query: 544 QQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQ 590
QQQQQ Q Q Q Q Q Q QQ QQQQQQ P ++ Q
Sbjct: 63 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQ 109
Score = 71.2 bits (173), Expect = 5e-12
Identities = 79/262 (30%), Positives = 107/262 (40%), Gaps = 41/262 (15%)
Query: 348 QQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQA 407
QQ+ P + +LQ A L+QQ Q+ + L Q+ + QQQQQ
Sbjct: 18 QQVLSPQQLQALLQQQQAVM--LQQQ--QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 73
Query: 408 QQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQ-QQQQQQQAHPHQFSQQ 466
QQQQQQ Q QQQQQQQ QQ QQ HP Q ++QQQQQ Q + Q
Sbjct: 74 QQQQQQ------------QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 121
Query: 467 QLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQL-----QQHQLQQQQLAQLQQQH 521
QL F QQ L QQLQ QQQH L Q L Q L Q L Q
Sbjct: 122 QLVFQQQLLQ--------MQQLQ--QQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSP 171
Query: 522 SLLQQQQQQ-----QIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQ 576
+ +QQ ++ ++ ++ S T+ + S+ S + H
Sbjct: 172 AEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASPPITHHSIVNGQSSV 231
Query: 577 QQQQQPPPSPQQ----HQLFGH 594
++ S ++ H L+GH
Sbjct: 232 LSARRDSSSHEETGASHTLYGH 253
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 85.1 bits (209), Expect = 3e-16
Identities = 104/428 (24%), Positives = 188/428 (43%), Gaps = 34/428 (7%)
Query: 172 EKTKKDEAFYHPRLIIYEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSG- 230
EKT++D+ EEE++ +++ + E ++D Q ++ QEG
Sbjct: 111 EKTQRDQQLNKQ----LEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHL 166
Query: 231 DQQFSPKSNTEKSKGELMFDDSSDSS---PEKQERNLNWTPAEVPQLAAAKRRLPQGKEP 287
+QQ + E+ +G+L + + PE+QE L E+P+ + LP+ +E
Sbjct: 167 EQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQL-----ELPEQQEGQLELPEQQE- 220
Query: 288 GLINLCANVPPVPGNI-LPPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNAD 346
G + L G + LP + G L + Q E SE ++ L + +
Sbjct: 221 GQLELPEQQE---GQLELPQQQEGQLELSEQQEGQLELSEQ---QEGQLKHLEHQEGQLE 274
Query: 347 I--QQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQ 404
+ +QM + L+ K+L+QQ + + + + H+ QQ+
Sbjct: 275 VPEEQMGQ----LKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQE 330
Query: 405 QQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFS 464
Q +Q ++Q L QQ QL+ + Q+ Q P+Q Q ++QQ Q +
Sbjct: 331 GQLEQLEEQEGQLKHLEQQEGQLEHLEHQE-GQLGLPEQQVLQLKQLEKQQGQPKHLEEE 389
Query: 465 QQQLQFPQQQLHPPQQLHRPQQQLQPFQQQ-HALQQQFHQLQQHQLQQQQLAQLQQQHSL 523
+ QL+ QQ + L + + QL+ ++Q L+QQ QL+ + Q+ QL L+QQ
Sbjct: 390 EGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQ 449
Query: 524 LQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQ---QPPQQQQQQ 580
L+ +QQ Q + L++ +Q + + Q HL + Q Q ++P Q QP +QQ+
Sbjct: 450 LEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEK--QEAQLELPEQQVGQPKHLEQQE 507
Query: 581 QPPPSPQQ 588
+ P+Q
Sbjct: 508 KHLEHPEQ 515
Score = 78.2 bits (191), Expect = 4e-14
Identities = 101/455 (22%), Positives = 191/455 (41%), Gaps = 42/455 (9%)
Query: 172 EKTKKDEAFYHPRLIIYEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPS-G 230
E K+DE + + E E++E + +E +E ++ + + QEG
Sbjct: 137 ELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELP 196
Query: 231 DQQFSPKSNTEKSKGELMFDDSSDSS---PEKQERNLNWTPAEVPQLAAAKRRLPQGKEP 287
+QQ E+ +G+L + + PE+QE L E+PQ + L + +E
Sbjct: 197 EQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQL-----ELPQQQEGQLELSEQQE- 250
Query: 288 GLINLCA-------NVPPVPGNI-LPPEVRGNL----MAAGQNLQSSERSEMIATWSPAV 335
G + L ++ G + +P E G L GQ ++ + +
Sbjct: 251 GQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQM 310
Query: 336 RTLRNITNN-ADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQ-GHTNANAVLFSQVK 393
L+++ + + + L+ K+LEQQ + H L Q
Sbjct: 311 GQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQV 370
Query: 394 VTPETHMLQQQQQAQQQQQQHPVLHLQPQQ-----IMQLQQQQQQQISQQPYPQQPPHPF 448
+ + QQ Q ++++ + HL Q+ ++Q + Q +QQ Q + +Q
Sbjct: 371 LQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQL 430
Query: 449 SQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ-PFQQQHALQQQFHQLQQH 507
++Q+ Q + Q QL+ P+QQ+ P+ L + ++QL+ P QQ+ ++ Q Q
Sbjct: 431 KHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQL 490
Query: 508 QLQQQQLAQ---LQQQHSLLQQQQQQQ-----IQQQQLQRMHQQQQQQQMQSQTAPHLSQ 559
+L +QQ+ Q L+QQ L+ +QQ ++QQ+ Q +QQ+ Q++
Sbjct: 491 ELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPG 550
Query: 560 TSQALQHQVPPQQ----PPQQQQQQQPPPSPQQHQ 590
Q +Q +P + P + QQQ+Q P +H+
Sbjct: 551 QVQDIQPALPTKGEVLLPVEHQQQKQEVQWPPKHK 585
Score = 72.0 bits (175), Expect = 3e-12
Identities = 58/203 (28%), Positives = 94/203 (46%), Gaps = 13/203 (6%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQ--QQQQQQI-------SQQPYPQQPPHPFSQQQ 452
QQ+ Q + QQQ L L QQ QL+ +QQ+ Q+ Q P++ +
Sbjct: 228 QQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLE 287
Query: 453 QQQQQAHPHQFSQQQLQFPQQQL----HPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQ 508
QQ+ Q ++Q + P+QQ+ H QQ +P+ Q Q L++Q QL+ +
Sbjct: 288 QQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLE 347
Query: 509 LQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQV 568
Q+ QL L+ Q L +QQ +Q +QL++ Q + + + HL Q L+H V
Sbjct: 348 QQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLV 407
Query: 569 PPQQPPQQQQQQQPPPSPQQHQL 591
+ +QQ++Q Q QL
Sbjct: 408 QQEGQLEQQERQVEHLEQQVGQL 430
Score = 70.5 bits (171), Expect = 8e-12
Identities = 102/431 (23%), Positives = 176/431 (40%), Gaps = 48/431 (11%)
Query: 190 EEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMF 249
E++++E +E+E++ + + E E QE + DQQ + + EK +
Sbjct: 76 EQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQR-DQQLNKQLEEEKK----LL 130
Query: 250 DDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVR 309
D D K++ L ++ +L P+ +E L +L G + PE +
Sbjct: 131 DQQLDQELVKRDEQLGMKKEQLLEL-------PEQQEGHLKHL----EQQEGQLKHPEQQ 179
Query: 310 GNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKN 369
GQ L+ E+ E + + Q+ P L+
Sbjct: 180 -----EGQ-LELPEQQEGQLELPEQQEGQLELPEQQE-GQLELPEQQEGQLELPEQQEGQ 232
Query: 370 LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQ 429
LE + Q+G + Q++++ QQ+ Q + + Q L + +Q+ QL+
Sbjct: 233 LE--LPQQQEGQLELSEQQEGQLELSE-----QQEGQLKHLEHQEGQLEVPEEQMGQLKY 285
Query: 430 QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
+QQ+ + QQ P +QQ Q H Q Q QQ+ +QL + QL+
Sbjct: 286 LEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQE-GQLEQLEEQEGQLK 344
Query: 490 PFQQQHA-LQQQFHQLQQHQLQQQQLAQLQQ--------QHSLLQQQQQQQIQQQ--QLQ 538
+QQ L+ HQ Q L +QQ+ QL+Q +H ++ Q + + QQ QL+
Sbjct: 345 HLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLK 404
Query: 539 RMHQQQQQQQMQSQTAPHLSQTSQALQH---QVPPQQPPQQQQQQQPPPSPQQHQ---LF 592
+ QQ+ Q + Q + HL Q L+H Q + +QQQ Q P Q Q L
Sbjct: 405 HLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLE 464
Query: 593 GHDPAVEIPEE 603
+ +E+PE+
Sbjct: 465 QEEKQLELPEQ 475
Score = 66.2 bits (160), Expect = 2e-10
Identities = 85/318 (26%), Positives = 135/318 (42%), Gaps = 52/318 (16%)
Query: 322 SERSEMIATWSPAV--RTLRNITN--NADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHS 377
S++ + T SPA+ L+ + N +QM +P+ + Q + P + + +
Sbjct: 2 SQQHTLPVTLSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKV--PVELPVEVPSKQ 59
Query: 378 QQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQ--QQQHPVLHLQ-------PQQIMQLQ 428
++ H A VK PE QQQ++ Q+Q QQQH H + QQ+ Q +
Sbjct: 60 EEKHMTA-------VKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEK 112
Query: 429 QQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFS---QQQLQFPQQQ----------- 474
Q+ QQ+++Q ++ QQ Q+ Q +Q L+ P+QQ
Sbjct: 113 TQRDQQLNKQL--EEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQE 170
Query: 475 ---LHPPQQ---LHRPQQQ----LQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLL 524
HP QQ L P+QQ P QQ+ L+ Q Q +L +QQ QL+
Sbjct: 171 GQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQE 230
Query: 525 QQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPP 584
Q + Q Q+ QL+ QQ+ Q ++ Q L L+HQ + P++Q Q
Sbjct: 231 GQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKH----LEHQEGQLEVPEEQMGQLKYL 286
Query: 585 SPQQHQLFGHDPAVEIPE 602
Q+ QL D + PE
Sbjct: 287 EQQEGQLKHLDQQEKQPE 304
>gi|18644886 forkhead box P1 isoform 1 [Homo sapiens]
Length = 677
Score = 84.0 bits (206), Expect = 7e-16
Identities = 70/192 (36%), Positives = 87/192 (45%), Gaps = 16/192 (8%)
Query: 399 HMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQ-PPHPFSQQQQQQQQ 457
H QQQQQA Q +Q + LQQQQQQQ+S P++ P Q
Sbjct: 53 HAQQQQQQALQVARQ-----------LLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAM 101
Query: 458 AHPHQFSQQQL-QFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQ 516
P + QQ+ Q QQQ+ PQQL QQ Q Q Q+F++ QQ QL QL
Sbjct: 102 MTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQL---QLQL 158
Query: 517 LQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQ 576
LQQQH+ Q ++QQQ+ QQL Q Q QQ+Q Q L + P P Q
Sbjct: 159 LQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQP 218
Query: 577 QQQQQPPPSPQQ 588
Q P QQ
Sbjct: 219 LAQGMIPTELQQ 230
Score = 68.2 bits (165), Expect = 4e-11
Identities = 60/192 (31%), Positives = 79/192 (41%), Gaps = 13/192 (6%)
Query: 450 QQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQL 509
QQQQQ Q QQQ Q L P++ + P Q Q Q+
Sbjct: 56 QQQQQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQI 115
Query: 510 QQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQ-QMQSQTAPHLSQTSQALQHQV 568
QQQ+ QQ LLQQQQ +QQQQLQ +++QQ+Q Q+Q H + + Q QV
Sbjct: 116 LQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKE-QQQV 174
Query: 569 PPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEIPEEGFLL----GCVFAIADYPEQMSDKQ 624
QQ QQQ Q QQH L + +G L + + M +
Sbjct: 175 ATQQLAFQQQLLQMQQLQQQHLL-------SLQRQGLLTIQPGQPALPLQPLAQGMIPTE 227
Query: 625 LLATWKRIIQAH 636
L WK + AH
Sbjct: 228 LQQLWKEVTSAH 239
Score = 68.2 bits (165), Expect = 4e-11
Identities = 74/205 (36%), Positives = 95/205 (46%), Gaps = 39/205 (19%)
Query: 371 EQQVNHSQQGHTN----ANAVLFSQVKVTPETHMLQQQQQAQQQQ----QQHPVLHLQPQ 422
+QQV+ + N A V S +TP+ QQ QQ QQQ QQ VL LQ Q
Sbjct: 75 QQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVL-LQQQ 133
Query: 423 QIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLH 482
Q + LQQQQ Q+ F ++QQ+ Q QLQ QQQ H +Q
Sbjct: 134 QALMLQQQQLQE-------------FYKKQQE----------QLQLQLLQQQ-HAGKQ-- 167
Query: 483 RPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQL-QRMH 541
P++Q Q QQ A QQQ LQ QLQQQ L LQ+Q L Q Q + Q L Q M
Sbjct: 168 -PKEQQQVATQQLAFQQQL--LQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMI 224
Query: 542 QQQQQQQMQSQTAPHLSQTSQALQH 566
+ QQ + T+ H ++ + H
Sbjct: 225 PTELQQLWKEVTSAHTAEETTGNNH 249
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/91 (37%), Positives = 42/91 (46%), Gaps = 6/91 (6%)
Query: 507 HQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTA---PHL---SQT 560
H QQQQ A + LLQQQQQQQ+ + + + +Q Q+ A P + Q
Sbjct: 53 HAQQQQQQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQM 112
Query: 561 SQALQHQVPPQQPPQQQQQQQPPPSPQQHQL 591
Q LQ QV Q Q QQQ QQ QL
Sbjct: 113 QQILQQQVLSPQQLQVLLQQQQALMLQQQQL 143
>gi|93277088 mediator of RNA polymerase II transcription, subunit 12
homolog (S. cerevisiae)-like [Homo sapiens]
Length = 2145
Score = 83.2 bits (204), Expect = 1e-15
Identities = 120/421 (28%), Positives = 166/421 (39%), Gaps = 69/421 (16%)
Query: 191 EEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFD 250
EEEEEE V E E+ S S +G + D++ K K+K
Sbjct: 1733 EEEEEEPTSPVSQEP----------ERKSAELSDQGKTTTDEEKKTKGRKRKTK------ 1776
Query: 251 DSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVR- 309
SS E + N+ P +++ PQ G NL P PG L +
Sbjct: 1777 -SSSRVDEYPQSNIYRVPPNYSPISSQMMHHPQSTLWGY-NLVGQ-PQQPGFFLQNQSLT 1833
Query: 310 ---GNLMAAGQNLQSSER---SEMIATWSPAVR---TLRNITNNADIQQMNRPSNVAHIL 360
L AG + ++ + S M+ S A+ +L IT+ + QM +L
Sbjct: 1834 PGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMMQPPSLHAITSQQQLIQMK-------LL 1886
Query: 361 QTLSAPTKNLEQQVNHSQQGHTNANAVLFS-QVKVTPETHMLQQQQQAQQQQQQHPVLHL 419
Q + Q QQG A LF+ Q + +P+ QQAQ Q + +
Sbjct: 1887 QQQQQQRLLRQAQTRPFQQGQPGDQAALFAAQARPSPQLPQYPGLQQAQTMPQGYTMYGT 1946
Query: 420 QPQQIMQLQQQQQQQI---------SQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQF 470
Q M LQQ QQQ + + YP +P ++ +Q Q P + QQQ
Sbjct: 1947 Q----MPLQQTSQQQAGSVVLSPSYNSRAYPAAHSNPVLMERLRQIQQQPSGYVQQQASP 2002
Query: 471 PQQQLHPPQQLHRPQQQLQPFQQQ--HALQQQFHQ------LQQHQLQQQQLAQLQQQHS 522
Q L Q+L+ Q P A+ H L Q ++ +Q Q++QQ
Sbjct: 2003 YLQPLTGSQRLNHQALQQSPLVGGGIDAVLTSAHPNLPSVPLPQDPMRPRQ-PQVRQQQR 2061
Query: 523 LLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVP--PQQPPQQQQQQ 580
LLQ QQ QQ Q QQ Q QQ Q QSQT QA+Q Q P P+Q QQ QQQ
Sbjct: 2062 LLQMQQPQQPQPQQPP---QPQQSSQSQSQTLG-----LQAMQPQQPLFPRQGLQQTQQQ 2113
Query: 581 Q 581
Q
Sbjct: 2114 Q 2114
Score = 55.8 bits (133), Expect = 2e-07
Identities = 39/96 (40%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 413 QHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQ 472
Q P+ QPQ + Q Q+ Q Q QQP PQQPP P QQ Q+ Q +Q PQ
Sbjct: 2046 QDPMRPRQPQ-VRQQQRLLQMQQPQQPQPQQPPQP-----QQSSQSQSQTLGLQAMQ-PQ 2098
Query: 473 QQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQ 508
Q L P Q L + QQQ Q LQ+Q Q Q
Sbjct: 2099 QPLFPRQGLQQTQQQQQTAALVRQLQKQLSSNQPQQ 2134
Score = 44.3 bits (103), Expect = 6e-04
Identities = 69/297 (23%), Positives = 108/297 (36%), Gaps = 27/297 (9%)
Query: 353 PSNVAHILQTLSAPTKNLEQQ-VNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQ 411
P ++ LQ L P + E++ + Q +A L Q K T + + ++ + +
Sbjct: 1718 PKPRSYYLQPLPLPPEEEEEEPTSPVSQEPERKSAELSDQGKTTTDEEKKTKGRKRKTKS 1777
Query: 412 QQHPVLHLQPQQIMQLQQQQQQQISQQP--YPQQPPHPFSQQQQQQQQAHPHQFSQQQLQ 469
+ PQ + IS Q +PQ ++ Q QQ P F Q Q
Sbjct: 1778 SSR--VDEYPQSNIYRVPPNYSPISSQMMHHPQSTLWGYNLVGQPQQ---PGFFLQNQ-- 1830
Query: 470 FPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQ 529
L P P P + AL + +Q L + Q L+Q +
Sbjct: 1831 ----SLTPGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMMQPPSLHAITSQQQLIQMKLL 1886
Query: 530 QQIQQQQLQRMHQQQ--QQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQ 587
QQ QQQ+L R Q + QQ Q Q A +Q P Q PQ QQ PQ
Sbjct: 1887 QQQQQQRLLRQAQTRPFQQGQPGDQAALFAAQAR-------PSPQLPQYPGLQQAQTMPQ 1939
Query: 588 QHQLFGHDPAVEIPEE----GFLLGCVFAIADYPEQMSDKQLLATWKRIIQAHGGTV 640
+ ++G ++ + +L + YP S+ L+ ++I Q G V
Sbjct: 1940 GYTMYGTQMPLQQTSQQQAGSVVLSPSYNSRAYPAAHSNPVLMERLRQIQQQPSGYV 1996
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 83.2 bits (204), Expect = 1e-15
Identities = 84/307 (27%), Positives = 120/307 (39%), Gaps = 36/307 (11%)
Query: 311 NLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQ-MNRPSNVAHILQTLSAPTKN 369
N +A QNL + + + +P V + + T++ +Q M + +LQ S P
Sbjct: 1000 NPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQ 1059
Query: 370 ------LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQ 423
L Q ++ Q +T A F+ +Q QQQ P+ H+Q
Sbjct: 1060 QSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPM 1119
Query: 424 IMQLQQQQQQQISQQPYP---QQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQ 480
+ Q Q Q QQ QP PP+P Q QQ H Q P Q+
Sbjct: 1120 LSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQE------ 1173
Query: 481 LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQ----------QHSLLQQQQQQ 530
QQQ Q QQQ QQQ L +Q +A +Q Q+ + Q+QQ
Sbjct: 1174 ----QQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1229
Query: 531 QI---QQQQLQRMHQQQQQQQMQSQTAPHLSQT---SQALQHQVPPQQPPQQQQQQQPPP 584
Q QQ + M+Q+QQ Q QSQ+ Q +Q+ Q P Q Q Q P
Sbjct: 1230 QSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1289
Query: 585 SPQQHQL 591
S Q+ Q+
Sbjct: 1290 SSQEQQV 1296
Score = 72.4 bits (176), Expect = 2e-12
Identities = 96/405 (23%), Positives = 156/405 (38%), Gaps = 49/405 (12%)
Query: 201 VENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQ 260
V+N Q G + + S Q G+ Q S S + + D+ + S E Q
Sbjct: 957 VQNSGTQQQGNGLFQQGNEMMSLQSGN---FLQQSSHSQAQLFHPQNPIADAQNLSQETQ 1013
Query: 261 ERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAGQ--- 317
+L +P + + Q +P + + + + + G+ +P + + + Q
Sbjct: 1014 G-SLFHSPNPIVHSQTSTTSSEQ-MQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPM 1071
Query: 318 -NLQSSERSEMIATWSP-AVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVN 375
NLQ++ ++ +P ++ L++ +N+ + + ++HI + + ++Q
Sbjct: 1072 NNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLS-----QEQAQ 1126
Query: 376 HSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQI 435
QQG L S + + Q QQ Q QH ++ +Q Q QQQQQQQ
Sbjct: 1127 PPQQGLFQPQVALGSL-----PPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQ 1181
Query: 436 SQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ---LQPFQ 492
QQ QQQQQQ +Q + + P+Q PP + P Q Q Q
Sbjct: 1182 QQQ-----------QQQQQQSILFSNQNTMATMASPKQP--PPNMIFNPNQNPMANQEQQ 1228
Query: 493 QQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQ 552
Q QQ + +Q QQ Q Q S LQ Q + Q H Q Q +Q
Sbjct: 1229 NQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGS 1288
Query: 553 TAPHLSQTS--------QALQHQVPPQQPPQQQQQQQPPPSPQQH 589
+ Q + ALQ + QQ QQ P SPQ +
Sbjct: 1289 PSSQEQQVTLFLSPASMSALQTSI-----NQQDMQQSPLYSPQNN 1328
Score = 65.1 bits (157), Expect = 3e-10
Identities = 74/258 (28%), Positives = 95/258 (36%), Gaps = 27/258 (10%)
Query: 349 QMNRPSNVAHILQTLSAPTK----NLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQ 404
Q+ P N Q LS T+ + + HSQ T++ + +LQ
Sbjct: 994 QLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGS 1053
Query: 405 QQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQ---QQQAHPH 461
Q QQ + L P +Q Q+ P P S +QQ QQQA
Sbjct: 1054 SVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPIS 1113
Query: 462 QFSQQQLQFPQQQLHPPQQ-LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQ 520
L Q+Q PPQQ L +PQ L Q Q Q Q Q Q
Sbjct: 1114 HIQTPMLS--QEQAQPPQQGLFQPQVALGSLPPNPMPQSQ----QGTMFQSQHSIVAMQS 1167
Query: 521 HSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPP-------QQP 573
+S Q+QQQQQ QQQQ QQQQQQ + + + A Q PP Q P
Sbjct: 1168 NSPSQEQQQQQQQQQQ------QQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNP 1221
Query: 574 PQQQQQQQPPPSPQQHQL 591
Q+QQ QQ +
Sbjct: 1222 MANQEQQNQSIFHQQSNM 1239
Score = 52.4 bits (124), Expect = 2e-06
Identities = 73/293 (24%), Positives = 108/293 (36%), Gaps = 24/293 (8%)
Query: 307 EVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAP 366
+++ ++ +Q S ++ + +++ ++ N+ QQ N + + +S
Sbjct: 923 QIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGN--EMMSLQ 980
Query: 367 TKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQ 426
+ N QQ +HSQ A LF + L Q+ Q +P++H Q
Sbjct: 981 SGNFLQQSSHSQ-------AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSS 1033
Query: 427 LQQQQQQQISQQPYP--QQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRP 484
Q Q SQ Q P QQ + + Q Q+ P
Sbjct: 1034 EQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISP 1093
Query: 485 QQQLQPFQQQHALQQQ--FHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQ 542
Q +QQ A QQQ +Q L Q+Q AQ QQ Q Q + M Q
Sbjct: 1094 LQSTSNSEQQAAFQQQAPISHIQTPMLSQEQ-AQPPQQGLF---QPQVALGSLPPNPMPQ 1149
Query: 543 QQQQQQMQSQTAPHLSQTSQALQHQVPPQ-QPPQQQQQQQPPPSPQQHQLFGH 594
QQ QSQ + A+Q P Q Q QQQQQQQ QQ LF +
Sbjct: 1150 SQQGTMFQSQ------HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSN 1196
Score = 44.7 bits (104), Expect = 5e-04
Identities = 116/579 (20%), Positives = 195/579 (33%), Gaps = 81/579 (13%)
Query: 202 ENEEQDS-QNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQ 260
ENE+Q Q + E + +Q+ S G S+ + L+ + + E Q
Sbjct: 582 ENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQ 641
Query: 261 ERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPP-VPGNILP-PEVRGNLMAAGQN 318
R + + V L+ Q ++ L + + NI P P L Q
Sbjct: 642 SREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQ 701
Query: 319 LQSSERSEMIATWSPA----VRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQV 374
LQ+ + A+ S V+ + + P ++ + LSA ++ QQV
Sbjct: 702 LQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSA---DIFQQV 758
Query: 375 NHSQQG-------------HTNANAVL---FSQVKVTPETHMLQQQQQAQQQQQQHPVLH 418
+ Q G HT + +L V E + QQQQ QQQQQ V+
Sbjct: 759 SQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQ---VME 815
Query: 419 LQPQQIMQLQQ---QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFS----QQQLQFP 471
+M++QQ Q QI + +P + QQ Q H S + +Q
Sbjct: 816 SSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQ 875
Query: 472 QQQLHPP-------------QQLHRP--------------QQQLQPFQQQHALQQQFHQL 504
+ P QQ+ P + Q Q Q+++ Q Q+
Sbjct: 876 CELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQM 935
Query: 505 QQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQAL 564
Q Q Q+ S++ Q QQQ + QQ + M Q+ L Q+S +
Sbjct: 936 QHSGDNQPQVNLFSSTKSMMSVQNSG--TQQQGNGLF-QQGNEMMSLQSGNFLQQSSHSQ 992
Query: 565 QHQVPPQQPPQQQQQQQP--------PPSPQQHQLFGHDPAVEIPEEGFLLGCVFAI--- 613
PQ P Q P+P H + ++ F A+
Sbjct: 993 AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQG 1052
Query: 614 ADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSAYAQAIRERKRCVT 673
+ P+ + + + TV + + Q +S Q +++
Sbjct: 1053 SSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPI 1112
Query: 674 AHWLNTVLKKKKMVPPHRALHFPV----AFPPGGKPCSQ 708
+H +L +++ PP + L P + PP P SQ
Sbjct: 1113 SHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQ 1151
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 83.2 bits (204), Expect = 1e-15
Identities = 84/307 (27%), Positives = 120/307 (39%), Gaps = 36/307 (11%)
Query: 311 NLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQ-MNRPSNVAHILQTLSAPTKN 369
N +A QNL + + + +P V + + T++ +Q M + +LQ S P
Sbjct: 1076 NPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQ 1135
Query: 370 ------LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQ 423
L Q ++ Q +T A F+ +Q QQQ P+ H+Q
Sbjct: 1136 QSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPM 1195
Query: 424 IMQLQQQQQQQISQQPYP---QQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQ 480
+ Q Q Q QQ QP PP+P Q QQ H Q P Q+
Sbjct: 1196 LSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQE------ 1249
Query: 481 LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQ----------QHSLLQQQQQQ 530
QQQ Q QQQ QQQ L +Q +A +Q Q+ + Q+QQ
Sbjct: 1250 ----QQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1305
Query: 531 QI---QQQQLQRMHQQQQQQQMQSQTAPHLSQT---SQALQHQVPPQQPPQQQQQQQPPP 584
Q QQ + M+Q+QQ Q QSQ+ Q +Q+ Q P Q Q Q P
Sbjct: 1306 QSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1365
Query: 585 SPQQHQL 591
S Q+ Q+
Sbjct: 1366 SSQEQQV 1372
Score = 72.4 bits (176), Expect = 2e-12
Identities = 96/405 (23%), Positives = 156/405 (38%), Gaps = 49/405 (12%)
Query: 201 VENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQ 260
V+N Q G + + S Q G+ Q S S + + D+ + S E Q
Sbjct: 1033 VQNSGTQQQGNGLFQQGNEMMSLQSGN---FLQQSSHSQAQLFHPQNPIADAQNLSQETQ 1089
Query: 261 ERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAGQ--- 317
+L +P + + Q +P + + + + + G+ +P + + + Q
Sbjct: 1090 G-SLFHSPNPIVHSQTSTTSSEQ-MQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPM 1147
Query: 318 -NLQSSERSEMIATWSP-AVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVN 375
NLQ++ ++ +P ++ L++ +N+ + + ++HI + + ++Q
Sbjct: 1148 NNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLS-----QEQAQ 1202
Query: 376 HSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQI 435
QQG L S + + Q QQ Q QH ++ +Q Q QQQQQQQ
Sbjct: 1203 PPQQGLFQPQVALGSL-----PPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQ 1257
Query: 436 SQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ---LQPFQ 492
QQ QQQQQQ +Q + + P+Q PP + P Q Q Q
Sbjct: 1258 QQQ-----------QQQQQQSILFSNQNTMATMASPKQP--PPNMIFNPNQNPMANQEQQ 1304
Query: 493 QQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQ 552
Q QQ + +Q QQ Q Q S LQ Q + Q H Q Q +Q
Sbjct: 1305 NQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGS 1364
Query: 553 TAPHLSQTS--------QALQHQVPPQQPPQQQQQQQPPPSPQQH 589
+ Q + ALQ + QQ QQ P SPQ +
Sbjct: 1365 PSSQEQQVTLFLSPASMSALQTSI-----NQQDMQQSPLYSPQNN 1404
Score = 65.1 bits (157), Expect = 3e-10
Identities = 74/258 (28%), Positives = 95/258 (36%), Gaps = 27/258 (10%)
Query: 349 QMNRPSNVAHILQTLSAPTK----NLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQ 404
Q+ P N Q LS T+ + + HSQ T++ + +LQ
Sbjct: 1070 QLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGS 1129
Query: 405 QQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQ---QQQAHPH 461
Q QQ + L P +Q Q+ P P S +QQ QQQA
Sbjct: 1130 SVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPIS 1189
Query: 462 QFSQQQLQFPQQQLHPPQQ-LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQ 520
L Q+Q PPQQ L +PQ L Q Q Q Q Q Q
Sbjct: 1190 HIQTPMLS--QEQAQPPQQGLFQPQVALGSLPPNPMPQSQ----QGTMFQSQHSIVAMQS 1243
Query: 521 HSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPP-------QQP 573
+S Q+QQQQQ QQQQ QQQQQQ + + + A Q PP Q P
Sbjct: 1244 NSPSQEQQQQQQQQQQ------QQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNP 1297
Query: 574 PQQQQQQQPPPSPQQHQL 591
Q+QQ QQ +
Sbjct: 1298 MANQEQQNQSIFHQQSNM 1315
Score = 52.4 bits (124), Expect = 2e-06
Identities = 73/293 (24%), Positives = 108/293 (36%), Gaps = 24/293 (8%)
Query: 307 EVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAP 366
+++ ++ +Q S ++ + +++ ++ N+ QQ N + + +S
Sbjct: 999 QIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGN--EMMSLQ 1056
Query: 367 TKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQ 426
+ N QQ +HSQ A LF + L Q+ Q +P++H Q
Sbjct: 1057 SGNFLQQSSHSQ-------AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSS 1109
Query: 427 LQQQQQQQISQQPYP--QQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRP 484
Q Q SQ Q P QQ + + Q Q+ P
Sbjct: 1110 EQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISP 1169
Query: 485 QQQLQPFQQQHALQQQ--FHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQ 542
Q +QQ A QQQ +Q L Q+Q AQ QQ Q Q + M Q
Sbjct: 1170 LQSTSNSEQQAAFQQQAPISHIQTPMLSQEQ-AQPPQQGLF---QPQVALGSLPPNPMPQ 1225
Query: 543 QQQQQQMQSQTAPHLSQTSQALQHQVPPQ-QPPQQQQQQQPPPSPQQHQLFGH 594
QQ QSQ + A+Q P Q Q QQQQQQQ QQ LF +
Sbjct: 1226 SQQGTMFQSQ------HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSN 1272
Score = 44.7 bits (104), Expect = 5e-04
Identities = 116/579 (20%), Positives = 195/579 (33%), Gaps = 81/579 (13%)
Query: 202 ENEEQDS-QNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQ 260
ENE+Q Q + E + +Q+ S G S+ + L+ + + E Q
Sbjct: 658 ENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQ 717
Query: 261 ERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPP-VPGNILP-PEVRGNLMAAGQN 318
R + + V L+ Q ++ L + + NI P P L Q
Sbjct: 718 SREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQ 777
Query: 319 LQSSERSEMIATWSPA----VRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQV 374
LQ+ + A+ S V+ + + P ++ + LSA ++ QQV
Sbjct: 778 LQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSA---DIFQQV 834
Query: 375 NHSQQG-------------HTNANAVL---FSQVKVTPETHMLQQQQQAQQQQQQHPVLH 418
+ Q G HT + +L V E + QQQQ QQQQQ V+
Sbjct: 835 SQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQ---VME 891
Query: 419 LQPQQIMQLQQ---QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFS----QQQLQFP 471
+M++QQ Q QI + +P + QQ Q H S + +Q
Sbjct: 892 SSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQ 951
Query: 472 QQQLHPP-------------QQLHRP--------------QQQLQPFQQQHALQQQFHQL 504
+ P QQ+ P + Q Q Q+++ Q Q+
Sbjct: 952 CELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQM 1011
Query: 505 QQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQAL 564
Q Q Q+ S++ Q QQQ + QQ + M Q+ L Q+S +
Sbjct: 1012 QHSGDNQPQVNLFSSTKSMMSVQNSG--TQQQGNGLF-QQGNEMMSLQSGNFLQQSSHSQ 1068
Query: 565 QHQVPPQQPPQQQQQQQP--------PPSPQQHQLFGHDPAVEIPEEGFLLGCVFAI--- 613
PQ P Q P+P H + ++ F A+
Sbjct: 1069 AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQG 1128
Query: 614 ADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSAYAQAIRERKRCVT 673
+ P+ + + + TV + + Q +S Q +++
Sbjct: 1129 SSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPI 1188
Query: 674 AHWLNTVLKKKKMVPPHRALHFPV----AFPPGGKPCSQ 708
+H +L +++ PP + L P + PP P SQ
Sbjct: 1189 SHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQ 1227
>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
sapiens]
Length = 1548
Score = 83.2 bits (204), Expect = 1e-15
Identities = 84/307 (27%), Positives = 120/307 (39%), Gaps = 36/307 (11%)
Query: 311 NLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQ-MNRPSNVAHILQTLSAPTKN 369
N +A QNL + + + +P V + + T++ +Q M + +LQ S P
Sbjct: 1093 NPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQ 1152
Query: 370 ------LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQ 423
L Q ++ Q +T A F+ +Q QQQ P+ H+Q
Sbjct: 1153 QSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPM 1212
Query: 424 IMQLQQQQQQQISQQPYP---QQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQ 480
+ Q Q Q QQ QP PP+P Q QQ H Q P Q+
Sbjct: 1213 LSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQE------ 1266
Query: 481 LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQ----------QHSLLQQQQQQ 530
QQQ Q QQQ QQQ L +Q +A +Q Q+ + Q+QQ
Sbjct: 1267 ----QQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1322
Query: 531 QI---QQQQLQRMHQQQQQQQMQSQTAPHLSQT---SQALQHQVPPQQPPQQQQQQQPPP 584
Q QQ + M+Q+QQ Q QSQ+ Q +Q+ Q P Q Q Q P
Sbjct: 1323 QSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1382
Query: 585 SPQQHQL 591
S Q+ Q+
Sbjct: 1383 SSQEQQV 1389
Score = 72.4 bits (176), Expect = 2e-12
Identities = 96/405 (23%), Positives = 156/405 (38%), Gaps = 49/405 (12%)
Query: 201 VENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQ 260
V+N Q G + + S Q G+ Q S S + + D+ + S E Q
Sbjct: 1050 VQNSGTQQQGNGLFQQGNEMMSLQSGN---FLQQSSHSQAQLFHPQNPIADAQNLSQETQ 1106
Query: 261 ERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAGQ--- 317
+L +P + + Q +P + + + + + G+ +P + + + Q
Sbjct: 1107 G-SLFHSPNPIVHSQTSTTSSEQ-MQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPM 1164
Query: 318 -NLQSSERSEMIATWSP-AVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVN 375
NLQ++ ++ +P ++ L++ +N+ + + ++HI + + ++Q
Sbjct: 1165 NNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLS-----QEQAQ 1219
Query: 376 HSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQI 435
QQG L S + + Q QQ Q QH ++ +Q Q QQQQQQQ
Sbjct: 1220 PPQQGLFQPQVALGSL-----PPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQ 1274
Query: 436 SQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ---LQPFQ 492
QQ QQQQQQ +Q + + P+Q PP + P Q Q Q
Sbjct: 1275 QQQ-----------QQQQQQSILFSNQNTMATMASPKQP--PPNMIFNPNQNPMANQEQQ 1321
Query: 493 QQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQ 552
Q QQ + +Q QQ Q Q S LQ Q + Q H Q Q +Q
Sbjct: 1322 NQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGS 1381
Query: 553 TAPHLSQTS--------QALQHQVPPQQPPQQQQQQQPPPSPQQH 589
+ Q + ALQ + QQ QQ P SPQ +
Sbjct: 1382 PSSQEQQVTLFLSPASMSALQTSI-----NQQDMQQSPLYSPQNN 1421
Score = 65.1 bits (157), Expect = 3e-10
Identities = 74/258 (28%), Positives = 95/258 (36%), Gaps = 27/258 (10%)
Query: 349 QMNRPSNVAHILQTLSAPTK----NLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQ 404
Q+ P N Q LS T+ + + HSQ T++ + +LQ
Sbjct: 1087 QLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGS 1146
Query: 405 QQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQ---QQQAHPH 461
Q QQ + L P +Q Q+ P P S +QQ QQQA
Sbjct: 1147 SVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPIS 1206
Query: 462 QFSQQQLQFPQQQLHPPQQ-LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQ 520
L Q+Q PPQQ L +PQ L Q Q Q Q Q Q
Sbjct: 1207 HIQTPMLS--QEQAQPPQQGLFQPQVALGSLPPNPMPQSQ----QGTMFQSQHSIVAMQS 1260
Query: 521 HSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPP-------QQP 573
+S Q+QQQQQ QQQQ QQQQQQ + + + A Q PP Q P
Sbjct: 1261 NSPSQEQQQQQQQQQQ------QQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNP 1314
Query: 574 PQQQQQQQPPPSPQQHQL 591
Q+QQ QQ +
Sbjct: 1315 MANQEQQNQSIFHQQSNM 1332
Score = 52.4 bits (124), Expect = 2e-06
Identities = 73/293 (24%), Positives = 108/293 (36%), Gaps = 24/293 (8%)
Query: 307 EVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAP 366
+++ ++ +Q S ++ + +++ ++ N+ QQ N + + +S
Sbjct: 1016 QIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGN--EMMSLQ 1073
Query: 367 TKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQ 426
+ N QQ +HSQ A LF + L Q+ Q +P++H Q
Sbjct: 1074 SGNFLQQSSHSQ-------AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSS 1126
Query: 427 LQQQQQQQISQQPYP--QQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRP 484
Q Q SQ Q P QQ + + Q Q+ P
Sbjct: 1127 EQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISP 1186
Query: 485 QQQLQPFQQQHALQQQ--FHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQ 542
Q +QQ A QQQ +Q L Q+Q AQ QQ Q Q + M Q
Sbjct: 1187 LQSTSNSEQQAAFQQQAPISHIQTPMLSQEQ-AQPPQQGLF---QPQVALGSLPPNPMPQ 1242
Query: 543 QQQQQQMQSQTAPHLSQTSQALQHQVPPQ-QPPQQQQQQQPPPSPQQHQLFGH 594
QQ QSQ + A+Q P Q Q QQQQQQQ QQ LF +
Sbjct: 1243 SQQGTMFQSQ------HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSN 1289
Score = 44.7 bits (104), Expect = 5e-04
Identities = 116/579 (20%), Positives = 195/579 (33%), Gaps = 81/579 (13%)
Query: 202 ENEEQDS-QNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQ 260
ENE+Q Q + E + +Q+ S G S+ + L+ + + E Q
Sbjct: 675 ENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQ 734
Query: 261 ERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPP-VPGNILP-PEVRGNLMAAGQN 318
R + + V L+ Q ++ L + + NI P P L Q
Sbjct: 735 SREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQ 794
Query: 319 LQSSERSEMIATWSPA----VRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQV 374
LQ+ + A+ S V+ + + P ++ + LSA ++ QQV
Sbjct: 795 LQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSA---DIFQQV 851
Query: 375 NHSQQG-------------HTNANAVL---FSQVKVTPETHMLQQQQQAQQQQQQHPVLH 418
+ Q G HT + +L V E + QQQQ QQQQQ V+
Sbjct: 852 SQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQ---VME 908
Query: 419 LQPQQIMQLQQ---QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFS----QQQLQFP 471
+M++QQ Q QI + +P + QQ Q H S + +Q
Sbjct: 909 SSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQ 968
Query: 472 QQQLHPP-------------QQLHRP--------------QQQLQPFQQQHALQQQFHQL 504
+ P QQ+ P + Q Q Q+++ Q Q+
Sbjct: 969 CELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQM 1028
Query: 505 QQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQAL 564
Q Q Q+ S++ Q QQQ + QQ + M Q+ L Q+S +
Sbjct: 1029 QHSGDNQPQVNLFSSTKSMMSVQNSG--TQQQGNGLF-QQGNEMMSLQSGNFLQQSSHSQ 1085
Query: 565 QHQVPPQQPPQQQQQQQP--------PPSPQQHQLFGHDPAVEIPEEGFLLGCVFAI--- 613
PQ P Q P+P H + ++ F A+
Sbjct: 1086 AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQG 1145
Query: 614 ADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSAYAQAIRERKRCVT 673
+ P+ + + + TV + + Q +S Q +++
Sbjct: 1146 SSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPI 1205
Query: 674 AHWLNTVLKKKKMVPPHRALHFPV----AFPPGGKPCSQ 708
+H +L +++ PP + L P + PP P SQ
Sbjct: 1206 SHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQ 1244
>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
sapiens]
Length = 1549
Score = 83.2 bits (204), Expect = 1e-15
Identities = 84/307 (27%), Positives = 120/307 (39%), Gaps = 36/307 (11%)
Query: 311 NLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQ-MNRPSNVAHILQTLSAPTKN 369
N +A QNL + + + +P V + + T++ +Q M + +LQ S P
Sbjct: 1094 NPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQ 1153
Query: 370 ------LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQ 423
L Q ++ Q +T A F+ +Q QQQ P+ H+Q
Sbjct: 1154 QSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPM 1213
Query: 424 IMQLQQQQQQQISQQPYP---QQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQ 480
+ Q Q Q QQ QP PP+P Q QQ H Q P Q+
Sbjct: 1214 LSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQE------ 1267
Query: 481 LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQ----------QHSLLQQQQQQ 530
QQQ Q QQQ QQQ L +Q +A +Q Q+ + Q+QQ
Sbjct: 1268 ----QQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1323
Query: 531 QI---QQQQLQRMHQQQQQQQMQSQTAPHLSQT---SQALQHQVPPQQPPQQQQQQQPPP 584
Q QQ + M+Q+QQ Q QSQ+ Q +Q+ Q P Q Q Q P
Sbjct: 1324 QSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1383
Query: 585 SPQQHQL 591
S Q+ Q+
Sbjct: 1384 SSQEQQV 1390
Score = 72.4 bits (176), Expect = 2e-12
Identities = 96/405 (23%), Positives = 156/405 (38%), Gaps = 49/405 (12%)
Query: 201 VENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQ 260
V+N Q G + + S Q G+ Q S S + + D+ + S E Q
Sbjct: 1051 VQNSGTQQQGNGLFQQGNEMMSLQSGN---FLQQSSHSQAQLFHPQNPIADAQNLSQETQ 1107
Query: 261 ERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAGQ--- 317
+L +P + + Q +P + + + + + G+ +P + + + Q
Sbjct: 1108 G-SLFHSPNPIVHSQTSTTSSEQ-MQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPM 1165
Query: 318 -NLQSSERSEMIATWSP-AVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVN 375
NLQ++ ++ +P ++ L++ +N+ + + ++HI + + ++Q
Sbjct: 1166 NNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLS-----QEQAQ 1220
Query: 376 HSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQI 435
QQG L S + + Q QQ Q QH ++ +Q Q QQQQQQQ
Sbjct: 1221 PPQQGLFQPQVALGSL-----PPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQ 1275
Query: 436 SQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ---LQPFQ 492
QQ QQQQQQ +Q + + P+Q PP + P Q Q Q
Sbjct: 1276 QQQ-----------QQQQQQSILFSNQNTMATMASPKQP--PPNMIFNPNQNPMANQEQQ 1322
Query: 493 QQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQ 552
Q QQ + +Q QQ Q Q S LQ Q + Q H Q Q +Q
Sbjct: 1323 NQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGS 1382
Query: 553 TAPHLSQTS--------QALQHQVPPQQPPQQQQQQQPPPSPQQH 589
+ Q + ALQ + QQ QQ P SPQ +
Sbjct: 1383 PSSQEQQVTLFLSPASMSALQTSI-----NQQDMQQSPLYSPQNN 1422
Score = 65.1 bits (157), Expect = 3e-10
Identities = 74/258 (28%), Positives = 95/258 (36%), Gaps = 27/258 (10%)
Query: 349 QMNRPSNVAHILQTLSAPTK----NLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQ 404
Q+ P N Q LS T+ + + HSQ T++ + +LQ
Sbjct: 1088 QLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGS 1147
Query: 405 QQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQ---QQQAHPH 461
Q QQ + L P +Q Q+ P P S +QQ QQQA
Sbjct: 1148 SVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPIS 1207
Query: 462 QFSQQQLQFPQQQLHPPQQ-LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQ 520
L Q+Q PPQQ L +PQ L Q Q Q Q Q Q
Sbjct: 1208 HIQTPMLS--QEQAQPPQQGLFQPQVALGSLPPNPMPQSQ----QGTMFQSQHSIVAMQS 1261
Query: 521 HSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPP-------QQP 573
+S Q+QQQQQ QQQQ QQQQQQ + + + A Q PP Q P
Sbjct: 1262 NSPSQEQQQQQQQQQQ------QQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNP 1315
Query: 574 PQQQQQQQPPPSPQQHQL 591
Q+QQ QQ +
Sbjct: 1316 MANQEQQNQSIFHQQSNM 1333
Score = 52.4 bits (124), Expect = 2e-06
Identities = 73/293 (24%), Positives = 108/293 (36%), Gaps = 24/293 (8%)
Query: 307 EVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAP 366
+++ ++ +Q S ++ + +++ ++ N+ QQ N + + +S
Sbjct: 1017 QIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGN--EMMSLQ 1074
Query: 367 TKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQ 426
+ N QQ +HSQ A LF + L Q+ Q +P++H Q
Sbjct: 1075 SGNFLQQSSHSQ-------AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSS 1127
Query: 427 LQQQQQQQISQQPYP--QQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRP 484
Q Q SQ Q P QQ + + Q Q+ P
Sbjct: 1128 EQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISP 1187
Query: 485 QQQLQPFQQQHALQQQ--FHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQ 542
Q +QQ A QQQ +Q L Q+Q AQ QQ Q Q + M Q
Sbjct: 1188 LQSTSNSEQQAAFQQQAPISHIQTPMLSQEQ-AQPPQQGLF---QPQVALGSLPPNPMPQ 1243
Query: 543 QQQQQQMQSQTAPHLSQTSQALQHQVPPQ-QPPQQQQQQQPPPSPQQHQLFGH 594
QQ QSQ + A+Q P Q Q QQQQQQQ QQ LF +
Sbjct: 1244 SQQGTMFQSQ------HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSN 1290
Score = 44.7 bits (104), Expect = 5e-04
Identities = 116/579 (20%), Positives = 195/579 (33%), Gaps = 81/579 (13%)
Query: 202 ENEEQDS-QNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQ 260
ENE+Q Q + E + +Q+ S G S+ + L+ + + E Q
Sbjct: 676 ENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQ 735
Query: 261 ERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPP-VPGNILP-PEVRGNLMAAGQN 318
R + + V L+ Q ++ L + + NI P P L Q
Sbjct: 736 SREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQ 795
Query: 319 LQSSERSEMIATWSPA----VRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQV 374
LQ+ + A+ S V+ + + P ++ + LSA ++ QQV
Sbjct: 796 LQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSA---DIFQQV 852
Query: 375 NHSQQG-------------HTNANAVL---FSQVKVTPETHMLQQQQQAQQQQQQHPVLH 418
+ Q G HT + +L V E + QQQQ QQQQQ V+
Sbjct: 853 SQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQ---VME 909
Query: 419 LQPQQIMQLQQ---QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFS----QQQLQFP 471
+M++QQ Q QI + +P + QQ Q H S + +Q
Sbjct: 910 SSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQ 969
Query: 472 QQQLHPP-------------QQLHRP--------------QQQLQPFQQQHALQQQFHQL 504
+ P QQ+ P + Q Q Q+++ Q Q+
Sbjct: 970 CELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQM 1029
Query: 505 QQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQAL 564
Q Q Q+ S++ Q QQQ + QQ + M Q+ L Q+S +
Sbjct: 1030 QHSGDNQPQVNLFSSTKSMMSVQNSG--TQQQGNGLF-QQGNEMMSLQSGNFLQQSSHSQ 1086
Query: 565 QHQVPPQQPPQQQQQQQP--------PPSPQQHQLFGHDPAVEIPEEGFLLGCVFAI--- 613
PQ P Q P+P H + ++ F A+
Sbjct: 1087 AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQG 1146
Query: 614 ADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSAYAQAIRERKRCVT 673
+ P+ + + + TV + + Q +S Q +++
Sbjct: 1147 SSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPI 1206
Query: 674 AHWLNTVLKKKKMVPPHRALHFPV----AFPPGGKPCSQ 708
+H +L +++ PP + L P + PP P SQ
Sbjct: 1207 SHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQ 1245
>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 83.2 bits (204), Expect = 1e-15
Identities = 84/307 (27%), Positives = 120/307 (39%), Gaps = 36/307 (11%)
Query: 311 NLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQ-MNRPSNVAHILQTLSAPTKN 369
N +A QNL + + + +P V + + T++ +Q M + +LQ S P
Sbjct: 1000 NPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGSSVPQDQ 1059
Query: 370 ------LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQ 423
L Q ++ Q +T A F+ +Q QQQ P+ H+Q
Sbjct: 1060 QSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPM 1119
Query: 424 IMQLQQQQQQQISQQPYP---QQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQ 480
+ Q Q Q QQ QP PP+P Q QQ H Q P Q+
Sbjct: 1120 LSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNSPSQE------ 1173
Query: 481 LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQ----------QHSLLQQQQQQ 530
QQQ Q QQQ QQQ L +Q +A +Q Q+ + Q+QQ
Sbjct: 1174 ----QQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1229
Query: 531 QI---QQQQLQRMHQQQQQQQMQSQTAPHLSQT---SQALQHQVPPQQPPQQQQQQQPPP 584
Q QQ + M+Q+QQ Q QSQ+ Q +Q+ Q P Q Q Q P
Sbjct: 1230 QSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1289
Query: 585 SPQQHQL 591
S Q+ Q+
Sbjct: 1290 SSQEQQV 1296
Score = 72.4 bits (176), Expect = 2e-12
Identities = 96/405 (23%), Positives = 156/405 (38%), Gaps = 49/405 (12%)
Query: 201 VENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQ 260
V+N Q G + + S Q G+ Q S S + + D+ + S E Q
Sbjct: 957 VQNSGTQQQGNGLFQQGNEMMSLQSGN---FLQQSSHSQAQLFHPQNPIADAQNLSQETQ 1013
Query: 261 ERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAGQ--- 317
+L +P + + Q +P + + + + + G+ +P + + + Q
Sbjct: 1014 G-SLFHSPNPIVHSQTSTTSSEQ-MQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPM 1071
Query: 318 -NLQSSERSEMIATWSP-AVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVN 375
NLQ++ ++ +P ++ L++ +N+ + + ++HI + + ++Q
Sbjct: 1072 NNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPISHIQTPMLS-----QEQAQ 1126
Query: 376 HSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQI 435
QQG L S + + Q QQ Q QH ++ +Q Q QQQQQQQ
Sbjct: 1127 PPQQGLFQPQVALGSL-----PPNPMPQSQQGTMFQSQHSIVAMQSNSPSQEQQQQQQQQ 1181
Query: 436 SQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQ---LQPFQ 492
QQ QQQQQQ +Q + + P+Q PP + P Q Q Q
Sbjct: 1182 QQQ-----------QQQQQQSILFSNQNTMATMASPKQP--PPNMIFNPNQNPMANQEQQ 1228
Query: 493 QQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQ 552
Q QQ + +Q QQ Q Q S LQ Q + Q H Q Q +Q
Sbjct: 1229 NQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGS 1288
Query: 553 TAPHLSQTS--------QALQHQVPPQQPPQQQQQQQPPPSPQQH 589
+ Q + ALQ + QQ QQ P SPQ +
Sbjct: 1289 PSSQEQQVTLFLSPASMSALQTSI-----NQQDMQQSPLYSPQNN 1328
Score = 65.1 bits (157), Expect = 3e-10
Identities = 74/258 (28%), Positives = 95/258 (36%), Gaps = 27/258 (10%)
Query: 349 QMNRPSNVAHILQTLSAPTK----NLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQ 404
Q+ P N Q LS T+ + + HSQ T++ + +LQ
Sbjct: 994 QLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQGS 1053
Query: 405 QQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQ---QQQAHPH 461
Q QQ + L P +Q Q+ P P S +QQ QQQA
Sbjct: 1054 SVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPIS 1113
Query: 462 QFSQQQLQFPQQQLHPPQQ-LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQ 520
L Q+Q PPQQ L +PQ L Q Q Q Q Q Q
Sbjct: 1114 HIQTPMLS--QEQAQPPQQGLFQPQVALGSLPPNPMPQSQ----QGTMFQSQHSIVAMQS 1167
Query: 521 HSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPP-------QQP 573
+S Q+QQQQQ QQQQ QQQQQQ + + + A Q PP Q P
Sbjct: 1168 NSPSQEQQQQQQQQQQ------QQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNP 1221
Query: 574 PQQQQQQQPPPSPQQHQL 591
Q+QQ QQ +
Sbjct: 1222 MANQEQQNQSIFHQQSNM 1239
Score = 52.4 bits (124), Expect = 2e-06
Identities = 73/293 (24%), Positives = 108/293 (36%), Gaps = 24/293 (8%)
Query: 307 EVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAP 366
+++ ++ +Q S ++ + +++ ++ N+ QQ N + + +S
Sbjct: 923 QIQNSVFQTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGN--EMMSLQ 980
Query: 367 TKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQ 426
+ N QQ +HSQ A LF + L Q+ Q +P++H Q
Sbjct: 981 SGNFLQQSSHSQ-------AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSS 1033
Query: 427 LQQQQQQQISQQPYP--QQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRP 484
Q Q SQ Q P QQ + + Q Q+ P
Sbjct: 1034 EQMQPPMFHSQSTIAVLQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISP 1093
Query: 485 QQQLQPFQQQHALQQQ--FHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQ 542
Q +QQ A QQQ +Q L Q+Q AQ QQ Q Q + M Q
Sbjct: 1094 LQSTSNSEQQAAFQQQAPISHIQTPMLSQEQ-AQPPQQGLF---QPQVALGSLPPNPMPQ 1149
Query: 543 QQQQQQMQSQTAPHLSQTSQALQHQVPPQ-QPPQQQQQQQPPPSPQQHQLFGH 594
QQ QSQ + A+Q P Q Q QQQQQQQ QQ LF +
Sbjct: 1150 SQQGTMFQSQ------HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSN 1196
Score = 44.7 bits (104), Expect = 5e-04
Identities = 116/579 (20%), Positives = 195/579 (33%), Gaps = 81/579 (13%)
Query: 202 ENEEQDS-QNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQ 260
ENE+Q Q + E + +Q+ S G S+ + L+ + + E Q
Sbjct: 582 ENEKQQQIQPKAYNPETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQ 641
Query: 261 ERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPP-VPGNILP-PEVRGNLMAAGQN 318
R + + V L+ Q ++ L + + NI P P L Q
Sbjct: 642 SREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNTIQQ 701
Query: 319 LQSSERSEMIATWSPA----VRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQV 374
LQ+ + A+ S V+ + + P ++ + LSA ++ QQV
Sbjct: 702 LQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSA---DIFQQV 758
Query: 375 NHSQQG-------------HTNANAVL---FSQVKVTPETHMLQQQQQAQQQQQQHPVLH 418
+ Q G HT + +L V E + QQQQ QQQQQ V+
Sbjct: 759 SQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQ---VME 815
Query: 419 LQPQQIMQLQQ---QQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFS----QQQLQFP 471
+M++QQ Q QI + +P + QQ Q H S + +Q
Sbjct: 816 SSAAMVMEMQQSICQAAAQIQSELFPSTASANGNLQQSPVYQQTSHMMSALSTNEDMQMQ 875
Query: 472 QQQLHPP-------------QQLHRP--------------QQQLQPFQQQHALQQQFHQL 504
+ P QQ+ P + Q Q Q+++ Q Q+
Sbjct: 876 CELFSSPPAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVFQTMVQM 935
Query: 505 QQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQAL 564
Q Q Q+ S++ Q QQQ + QQ + M Q+ L Q+S +
Sbjct: 936 QHSGDNQPQVNLFSSTKSMMSVQNSG--TQQQGNGLF-QQGNEMMSLQSGNFLQQSSHSQ 992
Query: 565 QHQVPPQQPPQQQQQQQP--------PPSPQQHQLFGHDPAVEIPEEGFLLGCVFAI--- 613
PQ P Q P+P H + ++ F A+
Sbjct: 993 AQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAVLQG 1052
Query: 614 ADYPEQMSDKQLLATWKRIIQAHGGTVDPTFTSRCTHLLCESQVSSAYAQAIRERKRCVT 673
+ P+ + + + TV + + Q +S Q +++
Sbjct: 1053 SSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQAPI 1112
Query: 674 AHWLNTVLKKKKMVPPHRALHFPV----AFPPGGKPCSQ 708
+H +L +++ PP + L P + PP P SQ
Sbjct: 1113 SHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQ 1151
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 80.5 bits (197), Expect = 8e-15
Identities = 97/317 (30%), Positives = 126/317 (39%), Gaps = 32/317 (10%)
Query: 298 PVPGNILPPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVA 357
P+P LP V+ + AA + + ++ I T ++ + +P+
Sbjct: 328 PIPAK-LPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAG-----QTQPNPGI 381
Query: 358 HILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVL 417
+Q P K Q G +N +L S + P+ Q Q Q +Q Q P
Sbjct: 382 LPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPT 441
Query: 418 HLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQ-------FSQQQLQF 470
PQQ Q Q +Q PQ F +QQQQQQQ P Q + QQQ Q
Sbjct: 442 ---PQQTPSTQAQGLPAQAQAT-PQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQT 497
Query: 471 PQ-QQLHPPQQLHRPQQQLQPFQQQHALQQQFHQ-LQQHQLQQQQLAQLQQQHSLLQQQ- 527
Q Q +HP Q +P P Q QQQ Q Q Q QQQQ Q QQ + L QQ
Sbjct: 498 QQFQAVHPATQ--QPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQ 555
Query: 528 ---QQQQIQQQQLQRMHQQQQQQQMQS-QTAPHLSQTSQALQHQVPPQQ--PPQQQQQQQ 581
QQ +QQ+ QQ Q Q + Q AP QA Q P Q PP Q Q+
Sbjct: 556 LMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQK 615
Query: 582 ----PPPSPQQHQLFGH 594
PPS + Q GH
Sbjct: 616 VGSLTPPSSPKTQRAGH 632
Score = 80.5 bits (197), Expect = 8e-15
Identities = 93/262 (35%), Positives = 109/262 (41%), Gaps = 41/262 (15%)
Query: 363 LSAPTKNLEQQVNHSQQ---GHTNAN-AVLFSQVKVTPETHM-LQQQQQAQQQQQQHPVL 417
L+ P E + Q+ G T N +L Q +TP +Q QA Q +L
Sbjct: 353 LTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLL 412
Query: 418 HLQPQQIMQ------LQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFP 471
PQ Q L Q Q +Q P PQQ P +Q Q QA P QQQL
Sbjct: 413 ASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQH--QQQLFLK 470
Query: 472 QQQLHPPQQLHRPQQQLQP----FQQQHALQQQFHQLQQHQLQQQQLAQ---LQQQHSLL 524
QQQ QQ P Q QP +QQQ A QQF Q QQ +AQ + Q S
Sbjct: 471 QQQ----QQQQPPPAQQQPAGTFYQQQQAQTQQF-QAVHPATQQPAIAQFPVVSQGGSQQ 525
Query: 525 QQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQ--TSQALQHQVPPQ---QPPQQQQQ 579
Q Q QQQQ Q QQQQQ Q TA H Q T QA Q P Q PQ Q
Sbjct: 526 QLMQNFYQQQQQQQ-----QQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPA 580
Query: 580 QQPPPSPQQHQLFGHDPAVEIP 601
P P+P Q +PA++ P
Sbjct: 581 AAPQPAPAQ------EPAIQAP 596
Score = 63.9 bits (154), Expect = 8e-10
Identities = 92/328 (28%), Positives = 124/328 (37%), Gaps = 46/328 (14%)
Query: 268 PAEVPQL-----AAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAGQN---- 318
PA++P+ AAAK+ P+ + L +P +I P + AGQ
Sbjct: 330 PAKLPEPVKASEAAAKKTQPKAR------LTDPIPTTETSIAPRQ----RPKAGQTQPNP 379
Query: 319 ----LQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQV 374
+Q + AT P + + + + +P A Q L Q
Sbjct: 380 GILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAP 439
Query: 375 NHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQ 434
QQ + L +Q + TP+ H Q + QQQQQQ P QP QQQ Q Q
Sbjct: 440 PTPQQTPSTQAQGLPAQAQATPQ-HQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQ 498
Query: 435 ISQQPYP--QQPP---HPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQ 489
Q +P QQP P Q QQQ + + QQQ Q QQQ QQL Q Q
Sbjct: 499 QFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQ---QQQLATALHQQQ 555
Query: 490 PFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQM 549
QQ ALQQ+ Q Q Q A Q + Q+ I Q +QQ
Sbjct: 556 LMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPA-----QEPAI---------QAPVRQQP 601
Query: 550 QSQTAPHLSQTSQALQHQVPPQQPPQQQ 577
+ QT P + Q + PP P Q+
Sbjct: 602 KVQTTPPPAVQGQKVGSLTPPSSPKTQR 629
>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
Length = 1161
Score = 78.6 bits (192), Expect = 3e-14
Identities = 55/130 (42%), Positives = 60/130 (46%), Gaps = 5/130 (3%)
Query: 421 PQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQ 480
PQQ LQQ QQ Q Q HP QQQQQQQQ Q QQQ Q QQQ H
Sbjct: 432 PQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHH 491
Query: 481 LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQ---QQHSLLQQQQQQQIQQQQL 537
H Q Q QHA QQQ Q+ Q Q + Q Q Q+ + Q QQ QQQ+
Sbjct: 492 HHHLLQDAYMQQYQHATQQQ--QMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQM 549
Query: 538 QRMHQQQQQQ 547
HQ QQQ
Sbjct: 550 LAQHQPSQQQ 559
Score = 74.7 bits (182), Expect = 4e-13
Identities = 57/150 (38%), Positives = 65/150 (43%), Gaps = 9/150 (6%)
Query: 441 PQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQ 500
PQQPP QQ QQ Q Q + P QQ QQ + QQQ Q QQQ QQ
Sbjct: 428 PQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQH 487
Query: 501 FHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQT 560
H H LQ + Q Q QQQQ +QQQ L MH Q Q SQ + Q
Sbjct: 488 HHHHHHHLLQDAYMQQYQH-----ATQQQQMLQQQFL--MHSVYQPQPSASQYPTMMPQY 540
Query: 561 SQAL--QHQVPPQQPPQQQQQQQPPPSPQQ 588
QA Q + QP QQQ + SPQ+
Sbjct: 541 QQAFFQQQMLAQHQPSQQQASPEYLTSPQE 570
Score = 73.6 bits (179), Expect = 1e-12
Identities = 48/118 (40%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
Query: 477 PPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQ 536
PPQQ + + LQ QQ QQ H +H QQQQ Q QQQ QQQQQQQ QQQQ
Sbjct: 427 PPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQ 486
Query: 537 LQRMHQQQQQQQMQSQTAPHLSQTSQALQHQ--VPPQQPPQQQQQQQPPPSPQQHQLF 592
H Q Q H +Q Q LQ Q + PQ Q P PQ Q F
Sbjct: 487 HHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAF 544
Score = 67.8 bits (164), Expect = 5e-11
Identities = 60/139 (43%), Positives = 65/139 (46%), Gaps = 23/139 (16%)
Query: 469 QFPQQQLHPPQQLHRPQQQLQP----FQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLL 524
Q P QQ PPQQ HR QQLQ QQ H + HQ QQ Q QQQQ Q QQQ
Sbjct: 425 QGPPQQ--PPQQ-HRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQ-QQQQQQQQQQ 480
Query: 525 QQQQQQQ--------IQQQQLQR-MHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQ 575
QQQQQQ +Q +Q+ H QQQQ +Q Q H Q Q P P
Sbjct: 481 QQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQY 540
Query: 576 QQ---QQQ---QPPPSPQQ 588
QQ QQQ Q PS QQ
Sbjct: 541 QQAFFQQQMLAQHQPSQQQ 559
Score = 62.8 bits (151), Expect = 2e-09
Identities = 52/129 (40%), Positives = 59/129 (45%), Gaps = 23/129 (17%)
Query: 482 HRPQQQLQPFQQQHAL---------QQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQI 532
HRP+ L+P L QQ LQQ Q +L QL QH QQQQQQ
Sbjct: 407 HRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQ 466
Query: 533 QQQQLQRMHQQQQQQQMQSQTA------PHLSQTSQALQHQVPPQQPPQQQQQ------Q 580
QQQQ Q+ QQQQQQQ Q Q HL Q + Q+Q QQ QQQ
Sbjct: 467 QQQQQQQ--QQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVY 524
Query: 581 QPPPSPQQH 589
QP PS Q+
Sbjct: 525 QPQPSASQY 533
Score = 62.8 bits (151), Expect = 2e-09
Identities = 62/172 (36%), Positives = 68/172 (39%), Gaps = 36/172 (20%)
Query: 352 RPSNVAHILQTLSAPTKNLEQQ--VNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQ 409
RP N IL P + +Q + QQG + H QQQQQ QQ
Sbjct: 414 RPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQH----RHPHQQQQQQQQQQ 469
Query: 410 QQQQHPVLHLQPQQIMQLQQQQQQQ--------ISQQPYPQQPPHPFSQQQQQQQQAHPH 461
QQQQ QQ Q QQQQQQQ + Q Y QQ H QQQ QQQ H
Sbjct: 470 QQQQ--------QQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMH 521
Query: 462 QFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQ 513
Q Q P +P PQ Q FQQQ L QHQ QQQ
Sbjct: 522 SVYQPQ---PSASQYPTMM---PQYQQAFFQQQ--------MLAQHQPSQQQ 559
Score = 32.0 bits (71), Expect = 3.2
Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 189 EEEEEEEEEEEEVENEEQDSQNEGSTDEKS---SPASSQEGSPSGDQQFSPKSNTEKSKG 245
+ EEEE+++EEV EQ N+ T+ ++ P +++ S S+ E++K
Sbjct: 752 KSSEEEEQDDEEVLQGEQGDFNDDDTEPENLGHRPLLMDSEDEEEEEKHSSDSDYEQAKA 811
Query: 246 EL-----MFDDSSDSSPEKQERNLNWTPAEV 271
+ ++ D S S P + + T A++
Sbjct: 812 KYSDMSSVYRDRSGSGPTQDLNTILLTSAQL 842
>gi|38787904 BMP-2 inducible kinase isoform b [Homo sapiens]
Length = 662
Score = 78.6 bits (192), Expect = 3e-14
Identities = 55/130 (42%), Positives = 60/130 (46%), Gaps = 5/130 (3%)
Query: 421 PQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQ 480
PQQ LQQ QQ Q Q HP QQQQQQQQ Q QQQ Q QQQ H
Sbjct: 432 PQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQHHHHH 491
Query: 481 LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQ---QQHSLLQQQQQQQIQQQQL 537
H Q Q QHA QQQ Q+ Q Q + Q Q Q+ + Q QQ QQQ+
Sbjct: 492 HHHLLQDAYMQQYQHATQQQ--QMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAFFQQQM 549
Query: 538 QRMHQQQQQQ 547
HQ QQQ
Sbjct: 550 LAQHQPSQQQ 559
Score = 73.6 bits (179), Expect = 1e-12
Identities = 48/118 (40%), Positives = 53/118 (44%), Gaps = 2/118 (1%)
Query: 477 PPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQ 536
PPQQ + + LQ QQ QQ H +H QQQQ Q QQQ QQQQQQQ QQQQ
Sbjct: 427 PPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQQQQQQQQQQQQQQQQQ 486
Query: 537 LQRMHQQQQQQQMQSQTAPHLSQTSQALQHQ--VPPQQPPQQQQQQQPPPSPQQHQLF 592
H Q Q H +Q Q LQ Q + PQ Q P PQ Q F
Sbjct: 487 HHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQYQQAF 544
Score = 67.8 bits (164), Expect = 5e-11
Identities = 60/139 (43%), Positives = 65/139 (46%), Gaps = 23/139 (16%)
Query: 469 QFPQQQLHPPQQLHRPQQQLQP----FQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLL 524
Q P QQ PPQQ HR QQLQ QQ H + HQ QQ Q QQQQ Q QQQ
Sbjct: 425 QGPPQQ--PPQQ-HRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQQQQQ-QQQQQQQQQQ 480
Query: 525 QQQQQQQ--------IQQQQLQR-MHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQ 575
QQQQQQ +Q +Q+ H QQQQ +Q Q H Q Q P P
Sbjct: 481 QQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVYQPQPSASQYPTMMPQY 540
Query: 576 QQ---QQQ---QPPPSPQQ 588
QQ QQQ Q PS QQ
Sbjct: 541 QQAFFQQQMLAQHQPSQQQ 559
Score = 62.8 bits (151), Expect = 2e-09
Identities = 52/129 (40%), Positives = 59/129 (45%), Gaps = 23/129 (17%)
Query: 482 HRPQQQLQPFQQQHAL---------QQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQI 532
HRP+ L+P L QQ LQQ Q +L QL QH QQQQQQ
Sbjct: 407 HRPKGALRPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQHRHPHQQQQQQQ 466
Query: 533 QQQQLQRMHQQQQQQQMQSQTA------PHLSQTSQALQHQVPPQQPPQQQQQ------Q 580
QQQQ Q+ QQQQQQQ Q Q HL Q + Q+Q QQ QQQ
Sbjct: 467 QQQQQQQ--QQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMHSVY 524
Query: 581 QPPPSPQQH 589
QP PS Q+
Sbjct: 525 QPQPSASQY 533
Score = 62.8 bits (151), Expect = 2e-09
Identities = 62/172 (36%), Positives = 68/172 (39%), Gaps = 36/172 (20%)
Query: 352 RPSNVAHILQTLSAPTKNLEQQ--VNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQ 409
RP N IL P + +Q + QQG + H QQQQQ QQ
Sbjct: 414 RPGNGPEILLGQGPPQQPPQQHRVLQQLQQGDWRLQQLHLQH----RHPHQQQQQQQQQQ 469
Query: 410 QQQQHPVLHLQPQQIMQLQQQQQQQ--------ISQQPYPQQPPHPFSQQQQQQQQAHPH 461
QQQQ QQ Q QQQQQQQ + Q Y QQ H QQQ QQQ H
Sbjct: 470 QQQQ--------QQQQQQQQQQQQQHHHHHHHHLLQDAYMQQYQHATQQQQMLQQQFLMH 521
Query: 462 QFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQ 513
Q Q P +P PQ Q FQQQ L QHQ QQQ
Sbjct: 522 SVYQPQ---PSASQYPTMM---PQYQQAFFQQQ--------MLAQHQPSQQQ 559
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 77.8 bits (190), Expect = 5e-14
Identities = 90/328 (27%), Positives = 129/328 (39%), Gaps = 74/328 (22%)
Query: 325 SEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHS---QQGH 381
S + +W + ++ +++ NRP + + L L P NLE Q + Q H
Sbjct: 1004 SNQLGSWPDGMLSMEQVSHGTQ----NRPL-LRNSLDDLVGPPSNLEGQSDERALLDQLH 1058
Query: 382 T---NANAVLFSQV-------KVTPETHMLQQQQQAQQQQ--------------QQHPV- 416
T N +A ++ ++ + L+ +Q A Q Q Q +P
Sbjct: 1059 TLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQ 1118
Query: 417 -------LHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQ------------QQQQQQQ 457
HLQ Q Q Q +P Q HP + + Q QQ+
Sbjct: 1119 GPPMQGGFHLQGQS-PSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQR 1177
Query: 458 AHPHQFSQQQLQFPQQQLHPPQQ----LHRPQQQLQPFQQQHALQQQF-----HQLQQHQ 508
QF Q Q + ++ P + RP Q Q QQ L Q +L H
Sbjct: 1178 LQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHH 1237
Query: 509 LQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQAL---- 564
+QQ++A + QQ QQQQQQQ QQQQ Q+ QQQQQQQ Q+ + P S ++
Sbjct: 1238 FRQQRVAMMMQQQQQQQQQQQQQ-QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLL 1296
Query: 565 ----QHQVPPQQPPQQQQQ---QQPPPS 585
Q PPQQ P Q QQP P+
Sbjct: 1297 AGPTMPQAPPQQFPYQPNYGMGQQPDPA 1324
Score = 47.4 bits (111), Expect = 7e-05
Identities = 61/221 (27%), Positives = 84/221 (38%), Gaps = 25/221 (11%)
Query: 370 LEQQVNHSQQG-HTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQ 428
+ QQ N QG H AN + TP+ +Q QQ+ Q QQ + Q +Q ++L+
Sbjct: 1142 MNQQGNFPLQGMHPRAN--IMRPRTNTPKQLRMQLQQRLQGQQFLN-----QSRQALELK 1194
Query: 429 QQQQQQISQQPY-PQQPPHPFSQQ--------QQQQQQAHPHQFSQQQLQFPQQQLHPPQ 479
+ P P SQQ Q+ ++ H F QQ++ QQ Q
Sbjct: 1195 MENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQ---QQ 1251
Query: 480 QLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLL-----QQQQQQQIQQ 534
Q + QQQ Q QQQ QQQ Q Q + LL Q QQ
Sbjct: 1252 QQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPY 1311
Query: 535 QQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQ 575
Q M QQ + + P+ +S+ Q P Q PQ
Sbjct: 1312 QPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQ 1352
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 77.4 bits (189), Expect = 7e-14
Identities = 88/324 (27%), Positives = 129/324 (39%), Gaps = 70/324 (21%)
Query: 325 SEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHS---QQGH 381
S + +W + ++ +++ NRP + + L L P NLE Q + Q H
Sbjct: 1004 SNQLGSWPDGMLSMEQVSHGTQ----NRPL-LRNSLDDLVGPPSNLEGQSDERALLDQLH 1058
Query: 382 T---NANAVLFSQV-------KVTPETHMLQQQQQAQQQQ--------------QQHPV- 416
T N +A ++ ++ + L+ +Q A Q Q Q +P
Sbjct: 1059 TLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQ 1118
Query: 417 -------LHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQ------------QQQQQQQ 457
HLQ Q Q Q +P Q HP + + Q QQ+
Sbjct: 1119 GPPMQGGFHLQGQS-PSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQR 1177
Query: 458 AHPHQFSQQQLQFPQQQLHPPQQ----LHRPQQQLQP-FQQQHALQQQFHQLQQHQLQQQ 512
QF Q Q + ++ P + RP Q Q F + Q+ +L H +QQ
Sbjct: 1178 LQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQ 1237
Query: 513 QLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQAL-------- 564
++A + QQ QQQQQQQ QQQQ Q+ QQQQQQQ Q+ + P S ++
Sbjct: 1238 RVAMMMQQQQQQQQQQQQQ-QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPT 1296
Query: 565 QHQVPPQQPPQQQQQ---QQPPPS 585
Q PPQQ P Q QQP P+
Sbjct: 1297 MPQAPPQQFPYQPNYGMGQQPDPA 1320
Score = 47.0 bits (110), Expect = 1e-04
Identities = 59/217 (27%), Positives = 83/217 (38%), Gaps = 21/217 (9%)
Query: 370 LEQQVNHSQQG-HTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQ 428
+ QQ N QG H AN + TP+ +Q QQ+ Q QQ + Q +Q ++L+
Sbjct: 1142 MNQQGNFPLQGMHPRAN--IMRPRTNTPKQLRMQLQQRLQGQQFLN-----QSRQALELK 1194
Query: 429 QQQQQQ-----ISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHR 483
+ + PQQ Q+ ++ H F QQ++ QQ QQ +
Sbjct: 1195 MENPTAGGAAVMRPMMQPQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQ---QQQQQQ 1251
Query: 484 PQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLL-----QQQQQQQIQQQQLQ 538
QQQ Q QQQ QQQ Q Q + LL Q QQ Q
Sbjct: 1252 QQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNY 1311
Query: 539 RMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQ 575
M QQ + + P+ +S+ Q P Q PQ
Sbjct: 1312 GMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQ 1348
>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
Length = 1200
Score = 77.4 bits (189), Expect = 7e-14
Identities = 99/324 (30%), Positives = 133/324 (41%), Gaps = 54/324 (16%)
Query: 300 PGNILPPEVRGNL----MAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSN 355
PGN + ++RGNL M G Q+ T+S A ++I+ S
Sbjct: 91 PGNHV--QLRGNLANSNMMWGAPAQAEPTDGYQYTYSQA----------SEIRTQKLTSG 138
Query: 356 VAHILQTLSA--PTKNLEQQVNHSQQGHTNANAV-----------LFSQVKVTPETHMLQ 402
V H L + + +NL QVN+ Q +AV L SQ + P +
Sbjct: 139 VLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIP 198
Query: 403 QQQQAQQQQQQHPV----LHLQPQQIMQ------LQQQQQQQISQQPY----PQQPPHPF 448
+ Q Q QQ HP L Q+ Q L QQ ++Q P P Q P
Sbjct: 199 SRYQ-QVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQML 257
Query: 449 SQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQ 508
SQ QQ QQ H + QQQ Q QQ++ Q++ QQ++P Q Q QQQ Q QQ Q
Sbjct: 258 SQHMQQMQQ-HQYYPPQQQQQAGQQRISM-QEIQTQPQQIRPSQPQPPPQQQ--QPQQLQ 313
Query: 509 LQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQV 568
LQQ+Q +Q Q Q +Q+QQ Q+MH Q PH QA Q+
Sbjct: 314 LQQRQ-GSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRD----PHQYTPEQAHTVQL 368
Query: 569 PPQQPPQQQQQQQPPPSPQQHQLF 592
P Q Q+ P P H L+
Sbjct: 369 IPLGSMSQYYYQE-PQQPYSHPLY 391
Score = 77.4 bits (189), Expect = 7e-14
Identities = 73/226 (32%), Positives = 90/226 (39%), Gaps = 20/226 (8%)
Query: 393 KVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQ 452
K+ T + Q Q VLH Q + +Q+ Q P +PP P +
Sbjct: 142 KLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQK-PMEPPAPAIPSR 200
Query: 453 QQQQQAHPHQFSQQQLQFPQQQL--HPPQ-----QLHRPQQQL-----QPFQQQHALQQQ 500
QQ PH L P Q+ HP Q +P Q+ QP Q L Q
Sbjct: 201 YQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQH 260
Query: 501 FHQLQQHQL---QQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHL 557
Q+QQHQ QQQQ A Q+ Q Q QQI+ Q Q QQQQ QQ+Q Q
Sbjct: 261 MQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGS 320
Query: 558 SQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEIPEE 603
Q Q Q Q Q +QQQQQ P H+ DP PE+
Sbjct: 321 MQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHR----DPHQYTPEQ 362
Score = 71.6 bits (174), Expect = 4e-12
Identities = 62/181 (34%), Positives = 76/181 (41%), Gaps = 13/181 (7%)
Query: 400 MLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQ--QQQISQQPY---PQQPPHPFSQQQQQ 454
ML Q Q QQ Q +P PQQ Q QQ+ Q+I QP P QP P QQQ Q
Sbjct: 256 MLSQHMQQMQQHQYYP-----PQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQ 310
Query: 455 QQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQL 514
Q Q Q S Q Q+ Q Q P Q + QQQ Q Q + + HQ Q QL
Sbjct: 311 QLQLQQRQGSMQIPQYYQPQ--PMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQL 368
Query: 515 AQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLS-QTSQALQHQVPPQQP 573
L Q+ QQ Q+ H Q QQ+ SQ + S + +QA+ P
Sbjct: 369 IPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGP 428
Query: 574 P 574
P
Sbjct: 429 P 429
Score = 68.9 bits (167), Expect = 2e-11
Identities = 65/191 (34%), Positives = 78/191 (40%), Gaps = 30/191 (15%)
Query: 408 QQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQ 467
QQ Q PV QP Q Q+ Q QQ+ Q Y PP QQQQQA + S Q+
Sbjct: 237 QQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQY--YPP-------QQQQQAGQQRISMQE 287
Query: 468 LQFPQQQLHPPQQLHRPQQQLQPFQ---QQHALQQQFHQLQQHQLQQQQLAQLQQQHSLL 524
+Q QQ+ P Q PQQQ QP Q QQ Q Q Q Q Q L + QQQ L
Sbjct: 288 IQTQPQQIRPSQPQPPPQQQ-QPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHL 346
Query: 525 Q------------QQQQQQIQQQQLQRMHQQQQQQQMQSQTAP-----HLSQTSQALQHQ 567
Q +Q +Q L M Q Q+ Q + P HLSQ Q Q
Sbjct: 347 QPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQ 406
Query: 568 VPPQQPPQQQQ 578
+ +Q Q
Sbjct: 407 LKTYSSDRQAQ 417
Score = 53.5 bits (127), Expect = 1e-06
Identities = 63/234 (26%), Positives = 86/234 (36%), Gaps = 22/234 (9%)
Query: 372 QQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQ 431
QQ Q+ T + SQ + P+ QQ Q Q+Q + QPQ +MQ Q+Q
Sbjct: 280 QQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQ 339
Query: 432 QQQIS--QQPYPQQPPHPFSQQQQQQQQAHP-HQFSQQQLQFPQQQLHPP--QQLHRPQQ 486
QQQ Q P + PH ++ +Q Q P SQ Q PQQ P QQ H Q
Sbjct: 340 QQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQH 399
Query: 487 QLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSL-LQQQQQQQIQQQQLQRMHQQQQ 545
Q Q++ QL+ + +Q A L L L R+
Sbjct: 400 Q----------QREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLP 449
Query: 546 QQQMQSQTAPHLSQTSQALQHQVPPQQPPQ------QQQQQQPPPSPQQHQLFG 593
+ + S + HL+ Q P PQ + Q P S Q FG
Sbjct: 450 HRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFG 503
Score = 32.3 bits (72), Expect = 2.5
Identities = 16/32 (50%), Positives = 20/32 (62%)
Query: 189 EEEEEEEEEEEEVENEEQDSQNEGSTDEKSSP 220
EEEEE EEEEEE E++ S E ++ SP
Sbjct: 956 EEEEELEEEEEEDPEEDRKSTKEEESEVPKSP 987
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 75.1 bits (183), Expect = 3e-13
Identities = 44/199 (22%), Positives = 105/199 (52%), Gaps = 4/199 (2%)
Query: 397 ETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQ 456
E M +Q++Q Q+Q++Q Q ++ + +Q++Q+ +Q Q ++Q++Q
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
Query: 457 QAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQL--QQHQLQQQQL 514
+ Q +Q+ Q +Q+ Q+ +Q+ Q +Q+ +++Q Q+ Q+ Q+++Q+
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324
Query: 515 AQLQQQHSLLQQQQQQQIQQQQLQRMHQQ--QQQQQMQSQTAPHLSQTSQALQHQVPPQQ 572
+Q+ + +Q++Q Q++Q+ + +Q +Q++QMQ Q Q Q + + ++
Sbjct: 325 QMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRK 384
Query: 573 PPQQQQQQQPPPSPQQHQL 591
+Q ++Q+ Q+ Q+
Sbjct: 385 QEEQMRKQEEQMGEQKEQM 403
Score = 75.1 bits (183), Expect = 3e-13
Identities = 41/197 (20%), Positives = 103/197 (52%), Gaps = 7/197 (3%)
Query: 397 ETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQ 456
E M +Q++Q Q+Q++Q +Q Q+ +Q++Q + ++ +Q Q++Q +Q
Sbjct: 233 EEQMGEQEEQVQKQEEQ-----VQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287
Query: 457 QAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQ 516
+ + +Q + +Q +Q+ ++Q++ ++Q Q++ Q+ Q+ +Q+
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQM 347
Query: 517 LQQQHSLLQQQQQQQIQQQQLQRMHQQ--QQQQQMQSQTAPHLSQTSQALQHQVPPQQPP 574
+Q+ + +Q++Q Q Q++Q+++ +Q +Q++QM+ Q Q Q + + +
Sbjct: 348 WKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQK 407
Query: 575 QQQQQQQPPPSPQQHQL 591
+Q ++Q+ Q+ Q+
Sbjct: 408 EQMREQEEQMGEQKEQM 424
Score = 67.4 bits (163), Expect = 7e-11
Identities = 45/204 (22%), Positives = 99/204 (48%), Gaps = 4/204 (1%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPH 461
Q ++Q Q +Q + Q +Q+ + ++Q Q+Q Q +Q Q++Q +Q
Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG--EQEEQMRKQEEQMGEQEEQV 243
Query: 462 QFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQL--QQQQLAQLQQ 519
Q ++Q+Q ++Q+ ++ R Q++ Q++ L+Q+ Q+ Q Q++Q+ + ++
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEE 303
Query: 520 QHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQ 579
Q ++Q ++Q +Q + Q +Q++QM Q Q Q + + + +Q Q+
Sbjct: 304 QMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQK 363
Query: 580 QQPPPSPQQHQLFGHDPAVEIPEE 603
Q+ Q+ Q+ + + EE
Sbjct: 364 QEEQVRKQEEQMRKQEEQMRKQEE 387
Score = 59.3 bits (142), Expect = 2e-08
Identities = 44/187 (23%), Positives = 95/187 (50%), Gaps = 13/187 (6%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQ---QQQQISQQPYPQQPPHPFSQQQQQQQQA 458
Q ++Q Q ++Q + Q Q+ + + Q Q+ Q+ +Q + ++Q+ Q +
Sbjct: 123 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 182
Query: 459 HPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQ 518
Q +Q+ Q +Q+ +Q + +Q + Q+Q +Q Q +Q + Q++Q+ + +
Sbjct: 183 QEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE--EQMGEQEEQMRKQEEQMGEQE 240
Query: 519 QQHSLLQQQQQQQIQQQQLQRMHQQ----QQQQQMQSQTAPHLSQTSQALQHQVPPQQPP 574
+Q Q+Q++Q+Q+Q+ Q Q+ +Q++QM+ Q L Q Q Q + +Q
Sbjct: 241 EQ----VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEE 296
Query: 575 QQQQQQQ 581
Q ++Q++
Sbjct: 297 QMREQEE 303
Score = 59.3 bits (142), Expect = 2e-08
Identities = 39/196 (19%), Positives = 99/196 (50%), Gaps = 9/196 (4%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQ---QQQQISQQPYPQQPPHPFSQQQQQQQQA 458
Q ++Q Q ++Q + Q Q+ + + Q Q+ Q+ +Q + ++Q+ Q
Sbjct: 137 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGE 196
Query: 459 HPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQ 518
Q +Q+ Q +Q+ +Q+ + ++Q+ ++Q Q++ Q+ Q+Q+Q+ Q+Q
Sbjct: 197 QEGQMGEQEEQMGEQE----EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE-EQVQ 251
Query: 519 -QQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQ 577
Q+ + +Q++Q + Q++Q++ +Q +Q+ Q++ + + ++ Q + ++Q
Sbjct: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ 311
Query: 578 QQQQPPPSPQQHQLFG 593
++Q +Q + G
Sbjct: 312 MREQEEQMREQEEQMG 327
Score = 56.2 bits (134), Expect = 2e-07
Identities = 40/194 (20%), Positives = 97/194 (50%), Gaps = 6/194 (3%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPH 461
Q ++Q Q ++Q + Q Q+ + + Q ++Q Q +Q Q+ Q +Q
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ--VREQEGQMGEQEGQMGEQEEQM 208
Query: 462 QFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQH 521
++Q+Q ++Q+ ++ R Q++ Q +Q+ +Q+Q Q+Q+ + Q ++ + ++
Sbjct: 209 GEQEEQMQKQEEQMGEQEEQMRKQEE-QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ 267
Query: 522 SLLQQQQQQQIQQQQLQRMHQQQ---QQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQ 578
++Q++Q+ +Q+ Q ++Q Q++QM+ Q Q Q + + ++ +Q
Sbjct: 268 EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMG 327
Query: 579 QQQPPPSPQQHQLF 592
+Q+ Q+ Q++
Sbjct: 328 KQEEQMWEQKEQMW 341
Score = 55.5 bits (132), Expect = 3e-07
Identities = 42/209 (20%), Positives = 103/209 (49%), Gaps = 7/209 (3%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQ---QQQQISQQPYPQQPPHPFSQQQQQQQQA 458
Q ++Q Q ++Q + Q Q+ + + Q Q+ Q+ +Q + ++Q+ Q +
Sbjct: 102 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 161
Query: 459 HPHQFSQQQLQFPQQQLHPPQQLHRPQQQL-QPFQQQHALQQQFHQL--QQHQLQQQQLA 515
Q +Q+ Q +Q+ +Q + ++Q Q +Q+ + +Q Q+ Q+ Q+Q+Q+
Sbjct: 162 QEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQ 221
Query: 516 QLQQQHSLLQQQQQQQIQQQQLQRMHQQ-QQQQQMQSQTAPHLSQTSQALQHQVPPQQPP 574
+Q+ + +Q++Q Q++Q+Q+ +Q Q+Q++ + + + + ++ Q
Sbjct: 222 MGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQ 281
Query: 575 QQQQQQQPPPSPQQHQLFGHDPAVEIPEE 603
++Q +Q+ Q+ Q+ + + EE
Sbjct: 282 KEQTEQEEQTGEQEEQMREQEEQMREQEE 310
Score = 51.2 bits (121), Expect = 5e-06
Identities = 45/210 (21%), Positives = 102/210 (48%), Gaps = 9/210 (4%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQ---QQQQISQQPYPQQPPHPFSQQQQQQQQA 458
Q ++Q Q ++Q + Q Q+ + + Q Q+ Q+ +Q + ++Q+ Q +
Sbjct: 74 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 133
Query: 459 HPHQFSQQQLQFPQQQLHPPQQLHRPQQQL-QPFQQQHALQQQFHQLQQHQLQ-QQQLAQ 516
Q +Q+ Q +Q+ +Q + ++Q Q +Q+ +++Q Q+++ + Q ++Q Q
Sbjct: 134 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 193
Query: 517 LQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQ 576
+ +Q + +Q++Q +Q++ Q+Q++QM Q Q Q + + Q+ +Q
Sbjct: 194 MGEQEGQMGEQEEQMGEQEE----QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQ 249
Query: 577 QQQQQPPPSPQQHQLFGHDPAVEIPEEGFL 606
Q+Q+ Q+ Q+ + + EE L
Sbjct: 250 VQKQEEQMRKQEEQMREQEEQMREQEEQML 279
Score = 30.8 bits (68), Expect = 7.1
Identities = 14/73 (19%), Positives = 34/73 (46%)
Query: 189 EEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELM 248
+EE+ E+EE+ E EEQ + + T+++ +E ++Q + + + E M
Sbjct: 260 QEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
Query: 249 FDDSSDSSPEKQE 261
+ ++++
Sbjct: 320 REQEEQMGKQEEQ 332
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 74.7 bits (182), Expect = 4e-13
Identities = 46/181 (25%), Positives = 104/181 (57%), Gaps = 2/181 (1%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPH 461
Q+Q++ Q++++Q L Q + + +++QQQQ ++ + +++QQ+++
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 462 QFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQH 521
+ +QQ + +QQL Q+ R +QQL+ Q++ +QQ + Q+ + ++QQL + QQ
Sbjct: 326 ERREQQEERREQQLRREQE-ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Query: 522 SLLQQQQQQQIQ-QQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQ 580
Q +++QQ++ +QQL+R Q +++QQ++ + Q + Q + +Q +Q++++
Sbjct: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
Query: 581 Q 581
Q
Sbjct: 445 Q 445
Score = 73.6 bits (179), Expect = 1e-12
Identities = 85/427 (19%), Positives = 179/427 (41%), Gaps = 53/427 (12%)
Query: 189 EEEEEEEEEEEEVENEEQDSQNEGS--TDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGE 246
EEE+ E EE++E + ++ SQ E +E+ QE D++F + E
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE----TDRKFREE--------E 1342
Query: 247 LMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPP 306
+ + + +QER+ + E+ ++ L + + +
Sbjct: 1343 QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQ----------------RLRRQ 1386
Query: 307 EVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRP-SNVAHILQTLSA 365
E + Q L+ ER + + R R Q+ +R ++
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLR--QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQER 1444
Query: 366 PTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIM 425
K LE++ Q+ H K E +LQ++++ Q +Q+ L+ +Q +
Sbjct: 1445 ERKFLEEEQQLRQERHR----------KFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494
Query: 426 QLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQ 485
+ Q++ ++ Q+ Q+P F +++QQ H Q ++ LQ QQ + R Q
Sbjct: 1495 RRQERDRKFREQELRSQEPERKF---LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ 1551
Query: 486 QQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQ 545
+ + F+++ L+Q+ + Q + ++ + +L++Q Q+Q+++ ++ + Q++ +Q+
Sbjct: 1552 DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE--QQLRRQEG 1609
Query: 546 QQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQ-----QHQLFGHDPAVEI 600
QQQ++ + + Q LQ + Q Q++ ++ PQ + Q HD +
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKF 1669
Query: 601 PEEGFLL 607
EE LL
Sbjct: 1670 REEEQLL 1676
Score = 67.8 bits (164), Expect = 5e-11
Identities = 52/198 (26%), Positives = 106/198 (53%), Gaps = 17/198 (8%)
Query: 397 ETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQ 456
E L++++Q ++QQQQ L+ +Q ++ +Q+++++ Q+ +Q Q+++++Q
Sbjct: 282 ERQELRRERQEEEQQQQR----LRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337
Query: 457 QAHPHQFS--QQQLQFPQQQLHPPQQLHRPQ------QQLQPFQQQHALQQQFHQLQQHQ 508
Q Q +QQL+ Q++ QQL R Q QQL+ QQ QQ + Q +
Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR 397
Query: 509 LQQ----QQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQA- 563
QQ QQL + QQ Q +++QQ++++Q + H+Q+ +Q+ + Q + +
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Query: 564 LQHQVPPQQPPQQQQQQQ 581
L+ + ++ Q++++QQ
Sbjct: 458 LKREEETERHEQERRKQQ 475
Score = 67.4 bits (163), Expect = 7e-11
Identities = 49/197 (24%), Positives = 112/197 (56%), Gaps = 10/197 (5%)
Query: 397 ETHMLQQQQQAQQQQ-QQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQ 455
ET + +++++ Q+++ Q+ L + +Q+ +L++Q+ ++ Q+ QQ QQ +++
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 456 QQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLA 515
Q+ + +QQ + +QQ QQ R +QQL+ +Q+ +QQ + Q+ + ++QQL
Sbjct: 310 QE---EERREQQEERREQQERREQQEERREQQLRR-EQEERREQQLRREQEEERREQQLR 365
Query: 516 QLQQQHSLLQQ--QQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQP 573
+ Q++ QQ ++QQ ++QQL+R Q +++QQ++ + + Q L+ + ++
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE---QQLRREQQLRREQQLRRE 422
Query: 574 PQQQQQQQPPPSPQQHQ 590
Q +++Q+ Q+H+
Sbjct: 423 QQLRREQEEERHEQKHE 439
Score = 67.4 bits (163), Expect = 7e-11
Identities = 54/218 (24%), Positives = 108/218 (49%), Gaps = 24/218 (11%)
Query: 371 EQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQ 430
EQQ+ ++ L SQ PE L+++QQ +QQ+Q L Q+ QL++Q
Sbjct: 1491 EQQLRRQERDRKFREQELRSQ---EPERKFLEEEQQLHRQQRQRKFL----QEEQQLRRQ 1543
Query: 431 QQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQP 490
++ Q +Q ++ F +++Q +Q+ Q S+Q+ ++ +Q R Q+Q +
Sbjct: 1544 ERGQQRRQDRDRK----FREEEQLRQEREEQQLSRQE---RDRKFRLEEQKVRRQEQERK 1596
Query: 491 FQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQR--------MHQ 542
F + QQ Q Q QL+Q++ + ++ LLQ++++QQ+ +Q+ R + +
Sbjct: 1597 FMEDE--QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654
Query: 543 QQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQ 580
Q+++QQ++ + Q LQ Q Q++ ++
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRK 1692
Score = 65.1 bits (157), Expect = 3e-10
Identities = 57/258 (22%), Positives = 127/258 (49%), Gaps = 29/258 (11%)
Query: 348 QQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQA 407
QQ++R LQ EQQ+ ++G + + E L+Q+++
Sbjct: 1522 QQLHRQQRQRKFLQE--------EQQLRRQERGQQRRQ----DRDRKFREEEQLRQEREE 1569
Query: 408 QQ--QQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQ 465
QQ +Q++ L+ Q++ + +Q+++ +Q +Q QQQ +Q++ + +
Sbjct: 1570 QQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE----GQQQLRQERDRKFREDE 1625
Query: 466 QQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQ 525
Q LQ ++Q QLHR ++ + +++ L++Q ++ QL+ + + +++ LLQ
Sbjct: 1626 QLLQEREEQ-----QLHRQERDRKFLEEEPQLRRQE---REQQLRHDRDRKFREEEQLLQ 1677
Query: 526 QQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPS 585
+ ++QQ+++Q+ R ++++QQ + + Q Q L+ Q ++ +++Q +Q
Sbjct: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQ---E 1734
Query: 586 PQQHQLFGHDPAVEIPEE 603
+Q QL + +I EE
Sbjct: 1735 TEQEQLRRQERYRKILEE 1752
Score = 62.8 bits (151), Expect = 2e-09
Identities = 45/223 (20%), Positives = 110/223 (49%), Gaps = 5/223 (2%)
Query: 371 EQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQ 430
+Q++ QQ Q + E ++QQ+ +++QQ + +Q ++ +Q+
Sbjct: 297 QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356
Query: 431 QQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQP 490
++++ Q Q+ Q +++QQ Q ++Q +QQL QQL R QQ +
Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR- 415
Query: 491 FQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQ---IQQQQLQRMHQQQQQQ 547
+QQ +QQ + Q+ + +Q+ Q +++ L ++Q++++ ++++ +R Q++++Q
Sbjct: 416 -EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQ 474
Query: 548 QMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQ 590
Q++ + L+ + +Q +++QQ + ++ Q
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Score = 62.4 bits (150), Expect = 2e-09
Identities = 77/441 (17%), Positives = 178/441 (40%), Gaps = 66/441 (14%)
Query: 187 IYEEEEEEE---------EEEEEVENEEQDSQNEGSTDEKS-------------SPASSQ 224
+++EEEE+E +EEE+++ EE Q E +E+ Q
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296
Query: 225 EGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQG 284
+ +QQ K E+ + + + + +++ER E + + R Q
Sbjct: 297 QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356
Query: 285 KEPGLINLCANVPPVPGNILPPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNN 344
+E L + Q ER E +R + +
Sbjct: 357 EERREQQL------------------------RREQEEERREQQLRREQQLRREQQLRRE 392
Query: 345 ADI---QQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHML 401
+ QQ+ R + Q EQQ+ Q+ + Q +
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQK--HEQERREQRLKRE 450
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPH 461
Q++++ ++++ H Q ++ QL++ Q+++ ++ + QQ++++QQ
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE 510
Query: 462 QFSQQQLQFP--------QQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQ 513
Q +++ + QQ+L QQL R Q++ +++ L+++ + + + ++Q+
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEE----RREQLLKREEEKRLEQERREQR 566
Query: 514 LAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQ---TSQALQHQVPP 570
L + Q++ +++++ +QQ+L+R +++ +Q+++ + L Q Q L+ + P
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 571 QQPPQQQQQQQPPPSPQQHQL 591
++ QQ + + +Q QL
Sbjct: 627 EERRQQLLKSEEQEERRQQQL 647
Score = 61.2 bits (147), Expect = 5e-09
Identities = 79/443 (17%), Positives = 191/443 (43%), Gaps = 34/443 (7%)
Query: 172 EKTKKDEAFYHPRLIIYEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGD 231
++ ++DE + R ++E EE EEE++++ + E +E+ E G
Sbjct: 165 DRQRRDEELWRQRQE-WQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGR 223
Query: 232 QQFSPKSNTEKSKGELMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLIN 291
++ K + + + +F + + K+E L ++ + ++R Q +E L
Sbjct: 224 EE---KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK 280
Query: 292 LCANVPPVPGNILPPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMN 351
L E+R Q Q R + + R R QQ
Sbjct: 281 LERQ-----------ELRRERQEEEQQQQRLRREQQLRRKQEEER--REQQEERREQQER 327
Query: 352 RPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQ 411
R Q L + +Q +Q L + + L+++QQ +++Q
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 412 QQHPVLHLQPQQIMQLQQQ---QQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQL 468
Q L+ +Q ++ +QQ +QQ +Q ++ Q++++ +Q H + +Q+L
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 469 QFPQQQ----LHPPQQLHRPQQQLQPFQ----QQHALQQQFHQLQQHQLQQQQLAQLQQQ 520
+ Q++ L ++ R +Q+ + Q Q+ ++++ +L++ + ++QQ + QQ
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ- 506
Query: 521 HSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQ 580
L+++Q+++ +Q+ ++ +++ QQ+++S+ L + + + Q+ ++ ++ +Q+
Sbjct: 507 ---LRREQEERREQRLKRQEEEERLQQRLRSE--QQLRREQEERREQLLKREEEKRLEQE 561
Query: 581 QPPPSPQQHQLFGHDPAVEIPEE 603
+ ++ Q D ++ EE
Sbjct: 562 RREQRLKREQEERRDQLLKREEE 584
Score = 60.8 bits (146), Expect = 6e-09
Identities = 78/457 (17%), Positives = 191/457 (41%), Gaps = 58/457 (12%)
Query: 147 EKYECALKRASIKIVTPDWVLDCVSEKTKKDEAFYHPRLIIYEEEEEEEEEE-------- 198
E+ E A +R +I W L+ ++ ++ + + PR + +E+EE+
Sbjct: 688 EEQEQARERIKSRIPKWQWQLESEAD-ARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
Query: 199 --EEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSS 256
+E E + Q E + + ++E S G Q+ S + + + + +
Sbjct: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQL------RA 800
Query: 257 PEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAG 316
E+Q+R + P E + ++R + KE L E +
Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRREREKEL--------------QFLEEEEQLQRRERA 846
Query: 317 QNLQSSE---RSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQ 373
Q LQ E + + S R + + ++ R H L A + L ++
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR----RHTLYAKPALQEQLRKE 902
Query: 374 VNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQ----------HPVLHLQPQQ 423
Q+ + + + ++++Q QQ+++Q Q ++
Sbjct: 903 QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK 962
Query: 424 IMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHR 483
+LQQ+++Q + ++P +++++Q++ ++ ++ Q +Q L ++ R
Sbjct: 963 DKKLQQKEEQLLGEEP----------EKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Query: 484 PQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQ 543
Q+ + ++++ LQQ+ QL + + ++++L + ++Q+ ++ QQ++ Q +R ++
Sbjct: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
Query: 544 QQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQ 580
+Q+ + Q + L Q + L + P ++ Q++++Q
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQ 1109
Score = 58.5 bits (140), Expect = 3e-08
Identities = 78/452 (17%), Positives = 192/452 (42%), Gaps = 41/452 (9%)
Query: 173 KTKKDEAFYHPRLIIYEEEEEEEEEEEEVENEEQDS--------------QNEGSTDEKS 218
K +++E RL + E EEE E+E+ EEQ+ Q E D +
Sbjct: 660 KREEEEERLEQRL---KREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ 716
Query: 219 SPASSQEGSPSGDQQFSPKSNTEKSK-GELMFDDSS----DSSPEKQERNLNWTPAEVPQ 273
S S+ G ++ + + + EL + + E+Q R+ W +
Sbjct: 717 SKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEK 776
Query: 274 LAAAKRRL---PQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAGQNLQSSERSEMIAT 330
++RL P +E L A PE Q + + + +
Sbjct: 777 SERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
Query: 331 WSPAVRTLR--NITNNADIQQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHT-NANAV 387
R R + D Q ++ + + LE++ ++ HT A
Sbjct: 837 EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEE--RKRRRHTLYAKPA 894
Query: 388 LFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHP 447
L Q++ E +LQ++++ Q++++ + +Q + Q ++++Q+ Q+ +Q
Sbjct: 895 LQEQLR--KEQQLLQEEEEELQREEREK----RRRQEQERQYREEEQLQQE--EEQLLRE 946
Query: 448 FSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQH 507
+++++Q++ ++ ++ Q +Q L + R Q++ + ++++ LQQ+ QL +
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Query: 508 QLQQQQLAQLQQQH---SLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQAL 564
+ ++++ + ++Q+ LQQ+++Q +++++ +R Q++++Q + + +
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Query: 565 QHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDP 596
+ + +Q ++Q +++ ++ QL +P
Sbjct: 1067 ERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Score = 56.6 bits (135), Expect = 1e-07
Identities = 77/421 (18%), Positives = 169/421 (40%), Gaps = 63/421 (14%)
Query: 189 EEEEEEEEEEEEVENEEQDSQ--------NEGSTDEKSSPASSQEGSPSGDQQFSPKSNT 240
EE+ +E EE+++ +E+D + + K Q G QQ + +
Sbjct: 1560 EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDR 1619
Query: 241 EKSKGELMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVP 300
+ + E + + + +QER+ + E PQL +R
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERDRKFLEEE-PQLRRQEREQQ------------------ 1660
Query: 301 GNILPPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHIL 360
L + Q LQ E ++ R R+ + QQ+ R L
Sbjct: 1661 ---LRHDRDRKFREEEQLLQEGEEQQLR-------RQERDRKFREEEQQLRRQERERKFL 1710
Query: 361 QT-LSAPTKNLEQQVNHSQQGHTNANAVLFSQV----KVTPETHMLQQQQQAQQQQQQHP 415
Q + LE++ +Q + K+ E + ++++ Q ++Q+
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 416 VLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQL 475
+ +Q+ Q +++QQ + Q+ F +++Q +Q+ Q QQ +
Sbjct: 1771 RKFREEEQLRQEREEQQLR------SQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE 1824
Query: 476 HPPQQLHRPQQQL-QPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQ 534
QL +Q+L Q +Q+ ++QF ++ + ++Q+L Q ++Q +Q++++++++
Sbjct: 1825 EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKR--RQERERKLRE 1882
Query: 535 QQLQRMHQQQQQQ----QMQSQTAPHLSQTSQALQHQ---VPPQQPP-----QQQQQQQP 582
+ ++R +++Q+ +++SQ + + HQ VP + P Q+Q+ Q
Sbjct: 1883 EHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQYR 1942
Query: 583 P 583
P
Sbjct: 1943 P 1943
Score = 56.2 bits (134), Expect = 2e-07
Identities = 67/405 (16%), Positives = 171/405 (42%), Gaps = 35/405 (8%)
Query: 189 EEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELM 248
+EEE E++EE E +E+ Q E E+ +E +QQ + E+ + +L
Sbjct: 310 QEEERREQQEERREQQERREQQE----ERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 249 FDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEV 308
+ + ++ R + + RR Q + + +
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR----------- 414
Query: 309 RGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTK 368
R + Q L+ + E R + + +Q R + +T +
Sbjct: 415 REQQLRREQQLRREQEEERHEQKHEQERREQRLKR----EQEERRDWLKREEETERHEQE 470
Query: 369 NLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQP-----QQ 423
+QQ+ Q+ + + + + +QQ + +Q++++ L Q QQ
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 424 IMQLQQQ---QQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQ 480
++ +QQ +Q++ +Q ++ Q++++Q+ + + QL +++ Q+
Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL-LKREEERRQQR 589
Query: 481 LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLA----QLQQQHSLLQQQQQQQIQQQQ 536
L R Q++ +Q +++ +L+Q + ++Q+L + +++ LL+ ++Q++ +QQQ
Sbjct: 590 LKREQEERL---EQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Query: 537 LQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQ 581
L+R Q++++Q+++ + + +H+ ++ +++Q+
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Score = 56.2 bits (134), Expect = 2e-07
Identities = 49/238 (20%), Positives = 114/238 (47%), Gaps = 42/238 (17%)
Query: 393 KVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQ--QQISQQPYPQQPPHPFSQ 450
K + L++Q+ QQ +Q+ + +Q++Q +++QQ +Q + + ++ P Q
Sbjct: 1596 KFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ 1655
Query: 451 QQQQQ-------------------------QQAHPHQFSQQQLQFPQQQ-----LHPPQQ 480
+++QQ +Q +F +++ Q +Q+ L QQ
Sbjct: 1656 EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQ 1715
Query: 481 LHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQR- 539
L R Q+ + F+++ L+Q+ Q Q +Q++ ++ ++ L ++++QQ+++Q+ R
Sbjct: 1716 LRR-QELERKFREEEQLRQETEQEQLR--RQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Query: 540 ------MHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQL 591
+ Q++++QQ++SQ + + + L+ + QQ QQ+ + +Q QL
Sbjct: 1773 FREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830
Score = 55.1 bits (131), Expect = 4e-07
Identities = 41/210 (19%), Positives = 109/210 (51%), Gaps = 10/210 (4%)
Query: 371 EQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQ-----QQQAQQQQQQHPVLHLQPQQIM 425
EQQ QQ ++K E LQQ QQ ++Q+++ L + ++
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
Query: 426 QLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQ 485
Q++++Q++ ++ ++ +++++QQ+ Q + + + ++++ +Q R +
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617
Query: 486 QQLQPFQ-QQHALQQQFHQLQQHQLQQQQLAQLQQQ--HSLLQQQQQQQIQQQQLQRMHQ 542
Q+L+ + ++ QQ +Q + +QQQL + QQ+ L+++++++ +Q+L+R H+
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
Query: 543 QQQQQQMQSQTAPHLSQTSQALQHQVPPQQ 572
+++++Q ++ Q + ++ ++P Q
Sbjct: 678 EERREQELAE--EEQEQARERIKSRIPKWQ 705
Score = 54.7 bits (130), Expect = 5e-07
Identities = 40/196 (20%), Positives = 110/196 (56%), Gaps = 21/196 (10%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQ--QAH 459
+++++ QQ+++Q L+ ++ + +Q+ ++Q ++ QQ +++++++ Q
Sbjct: 991 REEEELQQEEEQ----LLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 460 PHQF-SQQQLQFPQQQLHPPQQLHRPQQQLQ-PFQQQHALQQQFHQL----------QQH 507
Q+ +++LQ ++QL ++ R +Q+L+ ++++ LQQ+ QL Q+
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Query: 508 QLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQ---QQQQMQSQTAPHLSQTSQAL 564
+ Q ++ +LQQ+ L ++++++ ++Q+L+R ++++ QQ++ Q + Q L
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166
Query: 565 QHQVPPQQPPQQQQQQ 580
+ Q ++ QQ+++Q
Sbjct: 1167 ERQYREEEELQQEEEQ 1182
Score = 53.9 bits (128), Expect = 8e-07
Identities = 36/183 (19%), Positives = 103/183 (56%), Gaps = 22/183 (12%)
Query: 397 ETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQ 456
E +L ++++ +++Q+ L Q ++ +LQQ+++Q + ++P + ++Q++++
Sbjct: 1060 EEQLLGEERETRRRQE----LERQYRKEEELQQEEEQLLREEPEKR-------RRQERER 1108
Query: 457 QAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQ 516
Q + QQ+ +Q L ++ R Q+ + ++++ +QQ+ QL + + ++++ +
Sbjct: 1109 QCREEEELQQE---EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165
Query: 517 LQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQ 576
L++Q+ +++++ Q +++QL R Q++++Q+ + Q + + LQ Q Q+ +
Sbjct: 1166 LERQY---REEEELQQEEEQLLREEQEKRRQERERQ-----YREEEELQRQKRKQRYRDE 1217
Query: 577 QQQ 579
Q+
Sbjct: 1218 DQR 1220
Score = 53.9 bits (128), Expect = 8e-07
Identities = 46/219 (21%), Positives = 113/219 (51%), Gaps = 26/219 (11%)
Query: 393 KVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQ--QISQQPYPQQPPHPFSQ 450
K E +LQ+ ++ Q ++Q+ + +Q ++ Q+++++ Q QQ Q+ F +
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727
Query: 451 QQQQQQQAHPHQFSQQQLQ---FPQQQLHPP---QQLHRPQQQLQPFQQQHALQQQFHQL 504
++Q +Q+ Q +Q+ ++QL P QQL R Q++ + F+++ L+Q+
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR-QERDRKFREEEQLRQE---R 1783
Query: 505 QQHQLQQQQL-AQLQQQHSLLQQQQQQQI-----------QQQQLQRMHQQQQQQQMQSQ 552
++ QL+ Q+ + +++ L Q++++QQ+ +++QLQ ++Q+Q+ Q +
Sbjct: 1784 EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL--EEQEQRLRQER 1841
Query: 553 TAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQL 591
+ ++ A Q + ++ Q+++Q ++ +L
Sbjct: 1842 DRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880
Score = 53.5 bits (127), Expect = 1e-06
Identities = 47/240 (19%), Positives = 119/240 (49%), Gaps = 27/240 (11%)
Query: 348 QQMNRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQA 407
Q++ R + Q L + EQQ+ Q+ +L + + E +Q+ +
Sbjct: 517 QRLKRQEEEERLQQRLRS-----EQQLRREQE--ERREQLLKREEEKRLEQERREQRLKR 569
Query: 408 QQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQ 467
+Q++++ +L + ++ Q +++Q++ +Q ++ Q+++++Q+ + +++
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Query: 468 LQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQ 527
Q Q L +Q R QQQL+ QQ+ Q+ + ++ +L+Q+ L+++
Sbjct: 630 RQ---QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR-----------LKRE 675
Query: 528 QQQQIQQQQLQRMHQQQQQQQMQSQTAP---HLSQTSQALQHQV---PPQQPPQQQQQQQ 581
+++ ++Q+L Q+Q +++++S+ L + A Q +V P +Q Q+++Q+Q
Sbjct: 676 HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
Score = 52.0 bits (123), Expect = 3e-06
Identities = 64/416 (15%), Positives = 171/416 (41%), Gaps = 40/416 (9%)
Query: 188 YEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGEL 247
Y +EEE ++EEE++ EE + + E+ +E ++Q + ++ + EL
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRR---QERERQCREEEELQQEEEQLLREEREKRRRQEL 1136
Query: 248 MFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPE 307
+ +++E L E + +R+ + +E + +L E
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE---------LQQEEEQLLREE 1187
Query: 308 VRGNLMAAGQNLQSSE----------------RSEMIATWSPAVRTLRNITNNADIQQMN 351
+ + E RS++ W P N + +
Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE---NAVRDNKVYCKG 1244
Query: 352 RPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQ 411
R + L+ + +Q + H + + + H +++Q +++Q
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 412 QQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQ--QQQQAHPHQFSQQQLQ 469
++ + Q+ QL ++++++ ++ Q+ F +++Q Q+++ P + ++ +
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRR---QETDRKFREEEQLLQEREEQPLRRQERDRK 1361
Query: 470 FPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQ 529
F +++L +Q + ++ Q ++Q ++ + QQ + Q+++ Q + ++++Q
Sbjct: 1362 FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQ 1421
Query: 530 QQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQ----VPPQQPPQQQQQQQ 581
Q +Q++ ++ +++QQ + Q + L + Q Q + +Q Q++++QQ
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477
Score = 50.8 bits (120), Expect = 7e-06
Identities = 38/214 (17%), Positives = 104/214 (48%), Gaps = 28/214 (13%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQ----QQQQQ 457
++QQ+ +++Q++ L+ +++ +L+Q+++++ Q ++ P +QQ ++Q++
Sbjct: 585 RRQQRLKREQEERLEQRLKREEVERLEQEERRE---QRLKREEPEEERRQQLLKSEEQEE 641
Query: 458 AHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQ--------- 508
Q ++Q + +Q+L ++ R +Q+L+ ++ +Q+ + +Q Q
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Query: 509 ------LQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQ 562
L+ + A+ + +S ++Q+ Q+ +Q+Q ++ +++ + Q Q + H Q +
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Query: 563 ------ALQHQVPPQQPPQQQQQQQPPPSPQQHQ 590
Q Q + +Q+ PP +Q +
Sbjct: 762 EQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
Score = 50.4 bits (119), Expect = 9e-06
Identities = 36/196 (18%), Positives = 107/196 (54%), Gaps = 20/196 (10%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQ--QQQQAH 459
+++ + QQ+++Q L + ++ +LQ++++Q ++ Q+ ++++ ++Q+
Sbjct: 1021 RKKDELQQEEEQ---LLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
Query: 460 PHQFSQQQLQFPQQQL--HPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQL 517
+++LQ ++QL P++ R +++ Q +++ LQQ+ QL + + ++++ +L
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQ-CREEEELQQEEEQLLREEREKRRRQEL 1136
Query: 518 QQQHSLLQQQQQQQIQ----------QQQLQRMHQQQQQQQMQSQTAPHLSQTS--QALQ 565
++Q+ ++ QQ++ Q +Q+L+R ++++++ Q + + Q Q +
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERE 1196
Query: 566 HQVPPQQPPQQQQQQQ 581
Q ++ Q+Q+++Q
Sbjct: 1197 RQYREEEELQRQKRKQ 1212
Score = 49.7 bits (117), Expect = 1e-05
Identities = 35/188 (18%), Positives = 100/188 (53%), Gaps = 8/188 (4%)
Query: 400 MLQQQQQAQQQ-----QQQHPVLHLQPQQIMQLQQQQ-QQQISQQPYPQQPPHPFSQQQQ 453
+L+++++ +QQ Q++ L+ +++ +L+Q++ ++Q ++ P++ + +
Sbjct: 578 LLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
Query: 454 QQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQ 513
+Q++ Q ++Q + +Q+L ++ R +Q+L+ ++ +Q+ + +Q Q +++
Sbjct: 638 EQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERI 697
Query: 514 LAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQP 573
+++ + L+ + + Q + R +Q+ Q++ Q Q + S+ LQ Q +
Sbjct: 698 KSRIPKWQWQLESEADAR-QSKVYSRPRKQEGQRRRQEQEEKRRRRESE-LQWQEEERAH 755
Query: 574 PQQQQQQQ 581
QQQ+++Q
Sbjct: 756 RQQQEEEQ 763
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/200 (19%), Positives = 103/200 (51%), Gaps = 25/200 (12%)
Query: 397 ETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQ 456
E +L+++++ +++Q+ L Q ++ ++QQ+++Q + ++P +++++Q
Sbjct: 1120 EEQLLREEREKRRRQE----LERQYREEEEVQQEEEQLLREEP-----------EKRRRQ 1164
Query: 457 QAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQ 516
+ +++LQ ++QL +Q R Q++ + ++++ LQ+Q + +Q + Q +
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ--KRKQRYRDEDQRSD 1222
Query: 517 LQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQ 576
L+ Q + +++ ++ ++ ++ +Q + + Q+ Q LQH + QQ +
Sbjct: 1223 LKWQ---WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR 1279
Query: 577 QQ-----QQQPPPSPQQHQL 591
+Q QQ+ P++ QL
Sbjct: 1280 EQERRRWQQRDRHFPEEEQL 1299
Score = 47.8 bits (112), Expect = 6e-05
Identities = 38/209 (18%), Positives = 107/209 (51%), Gaps = 29/209 (13%)
Query: 402 QQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQ------QPYPQQPPHPFSQQQQQQ 455
+++Q+ Q+Q+++ Q ++ +L+Q+ +Q+ + Q + ++ ++Q Q
Sbjct: 136 RRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQS 195
Query: 456 QQAHPHQFSQQQLQFPQQQL-------HPPQQLHRPQQQLQPFQQQH---------ALQQ 499
+ H + + Q +++L +Q R ++Q + FQ++ L++
Sbjct: 196 CKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK 255
Query: 500 QFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQ 559
+ +LQ+ + Q+Q+ +LQ+ +++Q +++++Q+L+R Q+++QQQ + + L +
Sbjct: 256 EEEKLQEEEPQRQR--ELQE-----EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308
Query: 560 TSQALQHQVPPQQPPQQQQQQQPPPSPQQ 588
+ + + ++ QQ++++Q +Q
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQ 337
Score = 46.6 bits (109), Expect = 1e-04
Identities = 71/414 (17%), Positives = 163/414 (39%), Gaps = 70/414 (16%)
Query: 188 YEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGEL 247
Y EEEE ++EEE++ EE++ + ++Q+ K ++ + +L
Sbjct: 990 YREEEELQQEEEQLLREEREKRRR----------------QEWERQYRKKDELQQEEEQL 1033
Query: 248 MFDDSSD---SSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNIL 304
+ ++ E+Q R E QL +R + +E L
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE-----------------L 1076
Query: 305 PPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLS 364
+ R + LQ E + LR Q+ R LQ
Sbjct: 1077 ERQYRKE-----EELQQEEE-----------QLLREEPEKRRRQERERQCREEEELQQEE 1120
Query: 365 APTKNLEQQVNHSQQ---GHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQP 421
E++ Q+ + V + ++ E +++Q+ ++Q ++ L +
Sbjct: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
Query: 422 QQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQL 481
+Q+++ +Q++++Q ++ Y ++ +Q+++Q+ Q S + Q+ ++ + +
Sbjct: 1181 EQLLREEQEKRRQERERQYREE--EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238
Query: 482 H-----RPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQ 536
R +Q + + +Q Q QH L +QQ +Q+ QQ+ + +++Q
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ 1298
Query: 537 LQRMHQQQ-QQQQMQSQTAPHL-------SQTSQALQHQVPPQQPPQQQQQQQP 582
L+R Q++ +++ +SQ L + Q + ++ Q++++QP
Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352
Score = 46.6 bits (109), Expect = 1e-04
Identities = 31/164 (18%), Positives = 85/164 (51%), Gaps = 6/164 (3%)
Query: 426 QLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFP-QQQLHPPQQLHRP 484
Q +Q + Q+ + Q H +QQ++ ++ ++ Q+ FP ++QL +Q
Sbjct: 1249 QFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAK 1308
Query: 485 QQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQ 544
++ + +++ L++ + ++ + +Q+ + +++ LLQ++++Q +++Q+ R +++
Sbjct: 1309 RRDRKSQEEKQLLRE---EREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365
Query: 545 QQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQ 588
+ + Q Q L + Q L+ Q ++ +++QQ + QQ
Sbjct: 1366 ELRH-QEQGRKFLEE-EQRLRRQERERKFLKEEQQLRCQEREQQ 1407
Score = 43.9 bits (102), Expect = 8e-04
Identities = 27/167 (16%), Positives = 85/167 (50%), Gaps = 7/167 (4%)
Query: 422 QQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQL------ 475
+ ++Q ++Q++ Q +P +Q Q+++Q++Q + ++ + Q +Q+
Sbjct: 107 ESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDR 166
Query: 476 -HPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQ 534
++L R +Q+ Q +++ A ++Q + H+ ++ + ++ LL+ +++ + ++
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEK 226
Query: 535 QQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQ 581
QQ +R Q + Q+ + + + + ++ ++P +Q++ Q+
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Score = 38.1 bits (87), Expect = 0.045
Identities = 40/232 (17%), Positives = 100/232 (43%), Gaps = 54/232 (23%)
Query: 402 QQQQQAQQQQQQHPVL----------------HLQPQQIMQLQQQQQQQISQQPYPQQP- 444
QQQ + +QQ+++ L H + ++ +L +++Q+Q ++ + P
Sbjct: 644 QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPK 703
Query: 445 -------------------PHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQ 485
P Q+++Q+Q + + +LQ+ +++ QQ Q
Sbjct: 704 WQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763
Query: 486 QQLQPFQQQ----------------HALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQ 529
++ +Q Q +Q+ QL+ + QQ++ L ++ Q+++Q
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
Query: 530 QQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQ 581
++ ++++LQ + +++Q Q + + A L + LQ ++ +Q++ Q+
Sbjct: 824 RREREKELQFLEEEEQLQ--RRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Score = 32.7 bits (73), Expect = 1.9
Identities = 23/115 (20%), Positives = 51/115 (44%), Gaps = 10/115 (8%)
Query: 172 EKTKKDEAFYHPRLIIYEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGD 231
E+ ++ E + R I+ EE+ E EE+++ +E+D + + Q S D
Sbjct: 1738 EQLRRQERY---RKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD 1794
Query: 232 QQFSPKSNTEKSKGELMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKE 286
++F + + + E P++++ W ++ QL ++RL Q ++
Sbjct: 1795 RKFREEEQLRQEREE------QQLRPQQRDGKYRWEEEQL-QLEEQEQRLRQERD 1842
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 73.9 bits (180), Expect = 7e-13
Identities = 51/144 (35%), Positives = 83/144 (57%), Gaps = 17/144 (11%)
Query: 401 LQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHP 460
L+QQQQ QQQQQ+ P H I L Q+Q++I +Q ++ +QQ+++++
Sbjct: 369 LKQQQQLQQQQQRDPEAH-----IKHLLHQRQRRIEEQ---KEERRRVEEQQRREREQRK 420
Query: 461 HQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQ 520
Q +Q Q++L Q L R +++ Q ++Q ++Q + +Q + Q+ QLQQ+
Sbjct: 421 LQEKEQ-----QRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQR---QLQQE 472
Query: 521 HSLLQQQQQQQIQQQQLQRMHQQQ 544
H+ L+ QQQQ QQQQLQ+ QQQ
Sbjct: 473 HAYLKSLQQQQ-QQQQLQKQQQQQ 495
Score = 58.2 bits (139), Expect = 4e-08
Identities = 50/219 (22%), Positives = 111/219 (50%), Gaps = 13/219 (5%)
Query: 391 QVKVTPETHM-LQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFS 449
QV++ + H+ ++++ ++++ ++ + + ++ + I P F
Sbjct: 297 QVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFL 356
Query: 450 QQQQQQQQAHPHQFSQQQLQFPQQ---QLHPPQQLHRPQQQL--QPFQQQHALQQQFHQL 504
+ QQ+ + QQQLQ QQ + H LH+ Q+++ Q +++ +QQ +
Sbjct: 357 RLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRRER 416
Query: 505 QQHQLQQ-QQLAQLQQQHSLLQQQQQQQIQQQQ---LQRMHQQQQQQQMQSQTAPHLSQT 560
+Q +LQ+ +Q +L+ +L ++++++Q +++Q +++ +Q+Q +++Q Q +
Sbjct: 417 EQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYL 476
Query: 561 SQALQHQVPPQQPPQQQQQQQPP--PSPQQHQLFGHDPA 597
++LQ Q QQ +QQQQQ P P H G +PA
Sbjct: 477 -KSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPA 514
Score = 35.0 bits (79), Expect = 0.38
Identities = 60/313 (19%), Positives = 103/313 (32%), Gaps = 75/313 (23%)
Query: 196 EEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDS 255
+ + E+++++ E S E+ + +EG PS +S + L ++ S+S
Sbjct: 307 DRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNS 366
Query: 256 SPEKQERNLNWTPAEVPQ------LAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVR 309
KQ++ L P+ L +RR+ + KE
Sbjct: 367 EALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEE---------------------- 404
Query: 310 GNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVAHILQTLSAPTKN 369
+ Q ER + R L D+Q + R + K
Sbjct: 405 ---RRRVEEQQRREREQRKLQEKEQQRRLE------DMQALRREEERRQAEREQEYKRKQ 455
Query: 370 LEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQH-------PVLHL--- 419
LE+ Q+ L + QQQQQ Q+QQQQ P+ H
Sbjct: 456 LEE-----QRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRG 510
Query: 420 -----------QPQQIMQLQQQQQQQIS---------QQPYPQQ---PPHPFSQQQQQQQ 456
+ ++ ++ +QQ ++ + P PQ PP P SQ Q+
Sbjct: 511 MNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQR 570
Query: 457 QAHPHQFSQQQLQ 469
P + + LQ
Sbjct: 571 PVEPQEGPHKSLQ 583
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,252,208
Number of Sequences: 37866
Number of extensions: 2415601
Number of successful extensions: 73933
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 832
Number of HSP's successfully gapped in prelim test: 856
Number of HSP's that attempted gapping in prelim test: 22035
Number of HSP's gapped (non-prelim): 18743
length of query: 1069
length of database: 18,247,518
effective HSP length: 113
effective length of query: 956
effective length of database: 13,968,660
effective search space: 13354038960
effective search space used: 13354038960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.