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Search of human proteins with 93102361
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|93102361 palladin [Homo sapiens]
(1106 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|93102361 palladin [Homo sapiens] 2233 0.0
gi|153792294 myopalladin [Homo sapiens] 578 e-164
gi|110349721 titin isoform novex-3 [Homo sapiens] 270 4e-72
gi|110349719 titin isoform N2-A [Homo sapiens] 270 4e-72
gi|110349717 titin isoform novex-2 [Homo sapiens] 270 4e-72
gi|110349713 titin isoform novex-1 [Homo sapiens] 270 4e-72
gi|110349715 titin isoform N2-B [Homo sapiens] 270 4e-72
gi|209693444 myotilin isoform b [Homo sapiens] 243 7e-64
gi|5803106 myotilin isoform a [Homo sapiens] 243 7e-64
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 193 7e-49
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 193 7e-49
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 192 1e-48
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 192 1e-48
gi|118572606 hemicentin 1 [Homo sapiens] 136 1e-31
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 125 3e-28
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 125 3e-28
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 125 3e-28
gi|157785645 SPEG complex locus [Homo sapiens] 123 1e-27
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 122 1e-27
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 122 1e-27
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 102 2e-21
gi|224994173 roundabout 1 isoform d [Homo sapiens] 99 2e-20
gi|224994171 roundabout 1 isoform c [Homo sapiens] 99 2e-20
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 99 2e-20
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 99 2e-20
gi|19743806 roundabout 1 isoform b [Homo sapiens] 99 3e-20
gi|4506569 roundabout 1 isoform a [Homo sapiens] 99 3e-20
gi|109150416 peroxidasin [Homo sapiens] 98 5e-20
gi|7657359 contactin 5 isoform long [Homo sapiens] 98 5e-20
gi|28373129 contactin 5 isoform short [Homo sapiens] 98 5e-20
>gi|93102361 palladin [Homo sapiens]
Length = 1106
Score = 2233 bits (5786), Expect = 0.0
Identities = 1106/1106 (100%), Positives = 1106/1106 (100%)
Query: 1 MSGTSSHESFYDSLSDMQEESKNTDFFPGLSAFLSQEEINKSLDLARRAIADSETEDFDS 60
MSGTSSHESFYDSLSDMQEESKNTDFFPGLSAFLSQEEINKSLDLARRAIADSETEDFDS
Sbjct: 1 MSGTSSHESFYDSLSDMQEESKNTDFFPGLSAFLSQEEINKSLDLARRAIADSETEDFDS 60
Query: 61 EKEISQIFSTSPASLCEHPSHKETKLGEHASRRPQDNRSTPVQPLAEKQTKSISSPVSKR 120
EKEISQIFSTSPASLCEHPSHKETKLGEHASRRPQDNRSTPVQPLAEKQTKSISSPVSKR
Sbjct: 61 EKEISQIFSTSPASLCEHPSHKETKLGEHASRRPQDNRSTPVQPLAEKQTKSISSPVSKR 120
Query: 121 KPAMSPLLTRPSYIRSLRKAEKRGAKTPSTNVKPKTPHQRKGGPQSQLCDKAANLIEELT 180
KPAMSPLLTRPSYIRSLRKAEKRGAKTPSTNVKPKTPHQRKGGPQSQLCDKAANLIEELT
Sbjct: 121 KPAMSPLLTRPSYIRSLRKAEKRGAKTPSTNVKPKTPHQRKGGPQSQLCDKAANLIEELT 180
Query: 181 SIFKAAKPRNRSPNGESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGAR 240
SIFKAAKPRNRSPNGESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGAR
Sbjct: 181 SIFKAAKPRNRSPNGESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGAR 240
Query: 241 HCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTP 300
HCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTP
Sbjct: 241 HCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTP 300
Query: 301 RVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVF 360
RVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVF
Sbjct: 301 RVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVF 360
Query: 361 IEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQ 420
IEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQ
Sbjct: 361 IEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQ 420
Query: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE
Sbjct: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
Query: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS
Sbjct: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
Query: 541 ANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQ 600
ANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQ
Sbjct: 541 ANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQ 600
Query: 601 MQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKK 660
MQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKK
Sbjct: 601 MQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKK 660
Query: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATV 720
ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATV
Sbjct: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATV 720
Query: 721 FNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFE 780
FNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFE
Sbjct: 721 FNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFE 780
Query: 781 MKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA 840
MKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA
Sbjct: 781 MKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA 840
Query: 841 STLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDE 900
STLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDE
Sbjct: 841 STLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDE 900
Query: 901 NEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKML 960
NEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKML
Sbjct: 901 NEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKML 960
Query: 961 VRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG 1020
VRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG
Sbjct: 961 VRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG 1020
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAG
Sbjct: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
Query: 1081 WYTVSAKNEAGIVSCTARLDVYISRH 1106
WYTVSAKNEAGIVSCTARLDVYISRH
Sbjct: 1081 WYTVSAKNEAGIVSCTARLDVYISRH 1106
>gi|153792294 myopalladin [Homo sapiens]
Length = 1320
Score = 578 bits (1489), Expect = e-164
Identities = 349/901 (38%), Positives = 492/901 (54%), Gaps = 128/901 (14%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI-------HC 321
AAP F + L++ +EG V ECRV G P+P+V W+ EG + ++PD +I
Sbjct: 433 AAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMA 492
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG---ASSTDSDSESLAFKS 378
E ++ TL+IAE F +D+G +TC A+N G+ ++ A++ + G S+ S + + +
Sbjct: 493 EPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 552
Query: 379 RAGAMPQAQ---------------------------KKTTSVSLTIGSSSPKTGVTTAVI 411
A PQ + ++ + L + + P+ +
Sbjct: 553 LAAIEPQPSPPHSEPPSVEQPPKPKLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKGSEAS 612
Query: 412 QPLSVPVQQVHSPTSYLCRPDGTTTAYF---------PPVFTK-ELQNTAVAE--GQVVV 459
V + P S+ R +G T PPV K +L +T + + QV++
Sbjct: 613 SEAGVVTTRQTRPDSFQERFNGQATKTPEPSSPVKEPPPVLAKPKLDSTQLQQLHNQVLL 672
Query: 460 LECRVRGAPPLQVQWFRQGSEIQDS---PDFRILQKKPR-------STAEPEEI---CTL 506
+ +++ PP + F + +S P K+ + S A P+
Sbjct: 673 EQHQLQNPPPSSPKEFPFSMTVLNSNAPPAVTTSSKQVKAPSSQTFSLARPKYFFPSTNT 732
Query: 507 VIAETFPEDAGIFTCSARNDYGSAT-STAQLVVTSANTENCSYESMGESNNDHFQHFPPP 565
A P + +FT S+ T S L+V+ + + S + N P P
Sbjct: 733 TAATVAPSSSPVFTLSSTPQTIQRTVSKESLLVSHPSVQTKSPGGLSIQNE------PLP 786
Query: 566 PPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLING 625
P E + PS Q R + + R N V ++
Sbjct: 787 PGPTEPTPPPFTFSIPSGNQFQ-------PRCVSPIPVSPTSRIQNPV-------AFLSS 832
Query: 626 KANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLE 685
S ++P + P P + P G KK +++ + +D+ I+ TK+AVI+DL
Sbjct: 833 VLPSLPAIPPTNAMGLPRSAP----SMPSQGLAKKNTKSPQPVNDDNIRETKNAVIRDLG 888
Query: 686 RKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLI 745
+K+ F + N QEYK+SS EQRL+
Sbjct: 889 KKITFSDVRPNQ-----------------------------------QEYKISSFEQRLM 913
Query: 746 SEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPK 805
+EIE+RLER+PVDES DE+Q+ ++P +AP F+ +LKH+++ EG PVTFTC++ G P
Sbjct: 914 NEIEFRLERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPV 973
Query: 806 PKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGR 865
PK+YWFKDGKQIS +++H ++R+ DGTCSLH ++T DDDGNYTIMAANPQGRISC+G
Sbjct: 974 PKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGH 1033
Query: 866 LMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEG 925
LMVQ++ R R + H R RSR + EP+QERFFRPHFLQAPGD+ EG
Sbjct: 1034 LMVQSLPIRSRLTSAGQSH------RGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEG 1087
Query: 926 KLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCI 985
+LCR+DCKVSGLP P+L+W L+G+PV PD++HKMLVRE GVHSL+I+P+T RDAG Y CI
Sbjct: 1088 RLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCI 1147
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKK 1045
ATN+ GQNSFSLEL V AKE K PV +EKLQN GV +G+PVRLECRV+G+PPP +WKK
Sbjct: 1148 ATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKK 1207
Query: 1046 ENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISR 1105
+NE++ + +R+SMHQD GY CLLIQ A K DAGWYT+SAKNEAGIVSCTARLD+Y
Sbjct: 1208 DNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQW 1267
Query: 1106 H 1106
H
Sbjct: 1268 H 1268
Score = 341 bits (874), Expect = 3e-93
Identities = 256/688 (37%), Positives = 337/688 (48%), Gaps = 104/688 (15%)
Query: 5 SSHESFYDSLSDMQEESKNTDFFPGLSAFLSQEEINKSLDLARRAIADSETEDFDSEKEI 64
SS+ + S S E D P LSAFLSQEE+++S++LAR AI E D +
Sbjct: 38 SSNPCHFGSPSGAAEGGGGQDDLPDLSAFLSQEELDESVNLARLAINYDPLEKADETQAR 97
Query: 65 SQIFSTSPASLCEHPSHKETKLGEHASRRPQDNRSTPVQPLAEKQTKSISSPVSKRKPAM 124
++ S + K + S P + P P + K+ SP +
Sbjct: 98 KRL------------SPDQMKHSPNLSFEPNFCQDNPRSPTSSKE-----SPQEAK---- 136
Query: 125 SPLLTRPSYIRSLRKAEKRGAKTPSTNVKPKTPHQRKGGPQSQLCDKAANLIEELTSIFK 184
RP Y ++T S V +KAA+ IEEL+S+FK
Sbjct: 137 -----RPQYC----------SETQSKKV---------------FLNKAADFIEELSSLFK 166
Query: 185 AAKPRNRSPNG----------------ESSSPDSGYLSPKNQPSALLSASAS------QS 222
+ + P E+SS S + + S + A
Sbjct: 167 SHSSKRIRPRACKNHKSKLESQNKVMQENSSSFSDLSERRERSSVPIPIPADTRDNEVNH 226
Query: 223 PMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEV 282
+E Q RE + + D P + S L P PRF QKLRS+EV
Sbjct: 227 ALEQQEAKRREAEQAASEAAGGDT----TPGSSPSSLYYEEPLGQP--PRFTQKLRSREV 280
Query: 283 AEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRY 342
EG+RV L+C V G P P+VRW+CEGKEL N+PDI I + G+LH+L IAEAFE+DTGRY
Sbjct: 281 PEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI-VQAGNLHSLTIAEAFEEDTGRY 339
Query: 343 TCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSP 402
+C A+N G+D+TSAE++IEG SS+DS+ + + P + S I + P
Sbjct: 340 SCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVP 399
Query: 403 KTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLEC 462
+ V QP +QQ SPT+YL DG PVFTK LQN + +EGQ+VV EC
Sbjct: 400 QA--QHLVAQPRVATIQQCQSPTNYLQGLDGKPIIA-APVFTKMLQNLSASEGQLVVFEC 456
Query: 463 RVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCS 522
RV+GAP +V+W+R+G+ I+DSPDFRILQKKPRS AEPEEICTLVIAE F ED+G FTC+
Sbjct: 457 RVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCT 516
Query: 523 ARNDYGSATSTAQLVVTSAN--TENCSYESMGESNNDHFQHFPPPPPILETSSLELASKK 580
A N YG+ +S AQL V + N S S + N P PP E S+E K
Sbjct: 517 ASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTNLAAIEPQPSPPHSEPPSVEQPPKP 576
Query: 581 PSEIQQVN-NPELGLSRAALQMQFNAAERETN-------GVHPSR-----GVNGLINGKA 627
E VN N SR L++ FN E + GV +R NG+A
Sbjct: 577 KLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKGSEASSEAGVVTTRQTRPDSFQERFNGQA 636
Query: 628 NSNKSLPTPAVLLSPTKEPPPLLAKPKL 655
P P+ SP KEPPP+LAKPKL
Sbjct: 637 TKT---PEPS---SPVKEPPPVLAKPKL 658
Score = 81.3 bits (199), Expect = 5e-15
Identities = 65/277 (23%), Positives = 112/277 (40%), Gaps = 51/277 (18%)
Query: 774 GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
G P F KL+ ++ EG V C V G P P++ W+ +GK++ D + +Q G
Sbjct: 266 GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQA---GN 322
Query: 834 CSLHTTASTLDDD-GNYTIMAANPQGRISCTGRLMVQAVNQRGRS--------------- 877
T A ++D G Y+ A+N G S + + ++ V+
Sbjct: 323 LHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPN 382
Query: 878 -------------PRSPSGHPHVRRPRSRSRD---------SGDENEPIQERFFRPHFLQ 915
P P V +PR + G + +PI P F +
Sbjct: 383 EVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPI---IAAPVFTK 439
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE-------NGVHS 968
+L+ EG+L +C+V G P+P + W +G + ++L ++ + +
Sbjct: 440 MLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICT 499
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
L+I V + D+G +TC A+N+ G S +L V E
Sbjct: 500 LVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNE 536
Score = 71.6 bits (174), Expect = 4e-12
Identities = 59/223 (26%), Positives = 94/223 (42%), Gaps = 38/223 (17%)
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
EG C+V+G P P++ W +G+ + P + H + R+ G SL T D G Y
Sbjct: 1086 EGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRET-GVHSLLIDPLTQRDAGTY 1144
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 909
+A N G+ S + L V A +E
Sbjct: 1145 KCIATNKTGQNSFSLELSVVA----------------------------------KEVKK 1170
Query: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN--GVH 967
P L+ + V EG R++C+V G+P P W+ D + + P + ++ + ++ G
Sbjct: 1171 APVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETI-PCTRERISMHQDTTGYA 1229
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP 1010
L+I+P DAG YT A N AG S + L + A+ H+ P
Sbjct: 1230 CLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIP 1272
Score = 58.5 bits (140), Expect = 3e-08
Identities = 37/97 (38%), Positives = 56/97 (57%), Gaps = 6/97 (6%)
Query: 1008 KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 1067
+PP F +KL++ V +G V+L+C V+G+PPPQ+ W E + L +S D +H G +
Sbjct: 267 QPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPD---IHIVQAGNL 323
Query: 1068 -CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
L I A +ED G Y+ A N G S +A ++YI
Sbjct: 324 HSLTIAEAFEEDTGRYSCFASNIYGTDSTSA--EIYI 358
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 270 bits (691), Expect = 4e-72
Identities = 197/724 (27%), Positives = 328/724 (45%), Gaps = 76/724 (10%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP L+N V EG+ V LEC + G P V W+R+ +I+ S DF+I +
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG----- 996
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHF 559
I L+I E F ED+G FTCSA N+ G+ +++ L V + ++ E
Sbjct: 997 ---IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEE 1053
Query: 560 QHFPPPPPILETSSL----ELASKKPSEIQQVNNP------ELGLSRAALQMQFNAAER- 608
+ F ++ T + + +P+ + P E G Q+ N
Sbjct: 1054 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1113
Query: 609 --ETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTAR 666
+ +GV + G ++ + + ++ + ++ + K G ++
Sbjct: 1114 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLE 1173
Query: 667 IASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTY---------EERMARRLLGADS 717
A E + ++ ++ + +E + P Y E+ + R+ + D+
Sbjct: 1174 EADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1233
Query: 718 ATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDE----SGDEVQYGDVPVEN 773
V E +QE+ +SS E+RLI EIEYR+ ++ ++E G+E D+
Sbjct: 1234 VVVRTYVE------DQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESE 1287
Query: 774 GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
+ F+ ++K+Y+I EGM VTF C+++G P PKI W+KDGK+I + Y + DG
Sbjct: 1288 AVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGR 1346
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR----------------S 877
SL +D+G YT A+N +G C+G+L V+ G S
Sbjct: 1347 ASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLS 1406
Query: 878 PRSPSGHPHVRRPRSRS-----------------RDSGDENEPIQERFFRPHFLQAPGDL 920
PRS S P P S R + +E ER ++P F+ P
Sbjct: 1407 PRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSF 1466
Query: 921 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 980
EG+ R D KV G P P+ W DG+ + D HK++++E+G SLII P T D+G
Sbjct: 1467 KCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSG 1526
Query: 981 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ 1040
+T +A NRAG++S S+ L V A E P+F+EKL+N + +G + ++ R G P P
Sbjct: 1527 EWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPD 1586
Query: 1041 IFWKKENESLT-HSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
I W K ++ + H ++ + + G L I +D+ WYT +A N+AG + ++
Sbjct: 1587 IVWLKNSDIIVPHKYPKIRI-EGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKV 1645
Query: 1100 DVYI 1103
+V +
Sbjct: 1646 NVEV 1649
Score = 103 bits (258), Expect = 7e-22
Identities = 101/414 (24%), Positives = 174/414 (42%), Gaps = 61/414 (14%)
Query: 154 PKTPHQRKGGPQSQLCDKAANLIEELTSIFKAAKPRNRSPNGESSSPDSGYLSPKNQPSA 213
PKT H G ++ + A +++ S +A+ +S + P + + +P+
Sbjct: 824 PKTEH----GYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRV--RAEPTP 877
Query: 214 LLSASASQSPMEDQGEMEREVKSP---GARHCYQDNQDLAVPHNRKSHPQPHSALHFPAA 270
L + +P + E EVK + V H R++ + + P
Sbjct: 878 LPQFPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVE 937
Query: 271 -----PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGD 325
P + L++ V EG V LEC ++G P+P V W+ E ++ ++ D QI + G
Sbjct: 938 IPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG- 996
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ 385
+ L+I EAF +D+GR+TC A N +G+ +TS + ++ +
Sbjct: 997 IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ-------------------VSEE 1037
Query: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF--PPVF 443
+K+TT+V+ + + + V+ + S T P YF PV
Sbjct: 1038 FEKETTAVTEKFTTEEKRFVESRDVVMTDT-------SLTEEQAGPGEPAAPYFITKPVV 1090
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
K + EG VV C+V G P V W + G + +++ K T E
Sbjct: 1091 QK------LVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNK--QTGE---- 1138
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNND 557
C LVI+ TF +DAG +T RN +G +++A L+ E YE + +S +
Sbjct: 1139 CKLVISMTFADDAGEYTIVVRNKHGETSASASLL------EEADYELLMKSQQE 1186
Score = 101 bits (252), Expect = 3e-21
Identities = 65/191 (34%), Positives = 102/191 (53%), Gaps = 7/191 (3%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR-ENGVHSL 969
P F Q + V EG + +SG P P++SW DG+ + + + + +G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
I VT ++G Y+ ATN +GQ + + EL+V A+ A PP F+++LQ+ V G VRL
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA--PPNFVQRLQSMTVRQGSQVRL 123
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTD-RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
+ RV G+P P + + ++ + S D ++S D + LLI A ED+G Y+V+A N
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS---LLIAEAYPEDSGTYSVNATN 180
Query: 1089 EAGIVSCTARL 1099
G + TA L
Sbjct: 181 SVGRATSTAEL 191
Score = 95.9 bits (237), Expect = 2e-19
Identities = 95/393 (24%), Positives = 151/393 (38%), Gaps = 92/393 (23%)
Query: 759 ESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQIS 818
E DE Q +E P F +K +K EG F +V G P P+ +WF DG+QI
Sbjct: 1444 EETDESQ-----LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV 1498
Query: 819 PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
H + ++ DGT SL +T D G +T++A N GR S + L V+AV
Sbjct: 1499 NDYTHKVVIKE-DGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV------- 1550
Query: 879 RSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP 938
E +P F++ ++ ++EG M + +G P
Sbjct: 1551 ---------------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1583
Query: 939 TPDLSWQLDGKPVRPDSAHKMLVR-ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSL 997
PD+ W + + P K+ + G +L I+ S+D+ YT A N+AG+++
Sbjct: 1584 NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1643
Query: 998 ELVVAA-----------------------------------------------KEAHKPP 1010
++ V KE + P
Sbjct: 1644 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1703
Query: 1011 VFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
F +KL + + P ECR+ +G P + W + + L + +R+ M + GY
Sbjct: 1704 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPL-EAANRLRMINE-FGYCS 1761
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
L A D+G T A N+ G +A L V
Sbjct: 1762 LDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1794
Score = 93.2 bits (230), Expect = 1e-18
Identities = 68/261 (26%), Positives = 116/261 (44%), Gaps = 43/261 (16%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F L+ + EG TF ++G P P++ WF+DG+ IS + DG
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
L A T + G Y++ A N G+ + T L+V+A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------------------------- 99
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
E P P+F+Q +TV++G R+ +V+G+PTP + + DG ++ S
Sbjct: 100 ----ETAP-------PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQ-SS 147
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---AHKPPVF 1012
+ +E ++SL+I D+G Y+ ATN G+ + + EL+V +E A K
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 1013 IEKLQNTGVADGYPVRLECRV 1033
+ Q +++ R+E ++
Sbjct: 208 VSTAQ---ISESRQTRIEKKI 225
Score = 89.0 bits (219), Expect = 2e-17
Identities = 44/95 (46%), Positives = 69/95 (72%), Gaps = 1/95 (1%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A P F+Q+L+S V +GS+V L+ RVTG PTP V+++ +G E+ ++ D QI E GDL++
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQE-GDLYS 160
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
L+IAEA+ +D+G Y+ ATN G T++AE+ ++G
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195
Score = 87.8 bits (216), Expect = 5e-17
Identities = 91/327 (27%), Positives = 140/327 (42%), Gaps = 58/327 (17%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
F +K K+ E F C V+ P + W KD +++ +D IQ++ L
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQI-TDRIKIQKE-KYVHRLLI 3116
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
++ + D G YT++A G +S T +L V+ + R RS +
Sbjct: 3117 PSTRMSDAGKYTVVAG---GNVS-TAKLFVEGRDVRIRSIKK------------------ 3154
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV--RPDSA 956
E + I+++ +A + V E + D W DG + +
Sbjct: 3155 -EVQVIEKQ-------RAVVEFEVNEDDV-------------DAHWYKDGIEINFQVQER 3193
Query: 957 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
HK +V E +H + I DAG YT +A G+N S+ L V A E PP +++L
Sbjct: 3194 HKYVV-ERRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYVNAPE---PPQVLQEL 3245
Query: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 1076
Q V G P R + G P P+I W KE + L+ +H D Y LLI+ A
Sbjct: 3246 QPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLH-DGQEYTLLLIE-AFP 3303
Query: 1077 EDAGWYTVSAKNEAGIVSCTARLDVYI 1103
EDA YT AKN+ G+ + +A L V +
Sbjct: 3304 EDAAVYTCEAKNDYGVATTSASLSVEV 3330
Score = 83.6 bits (205), Expect = 1e-15
Identities = 62/199 (31%), Positives = 88/199 (44%), Gaps = 12/199 (6%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P LQ +TVQ GK R +SG P P +SW + + + K L + ++L+
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL-HDGQEYTLL 3297
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP--------PVFIEKLQNTGVA 1022
+ DA +YTC A N G + S L V E P P I LQ+T +
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3357
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
+G P R +CRV G ++ K+ + R++ +D + L I A ED G Y
Sbjct: 3358 EGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQ---LEIAEAYPEDEGTY 3414
Query: 1083 TVSAKNEAGIVSCTARLDV 1101
T A N G VS TA L +
Sbjct: 3415 TFVASNAVGQVSSTANLSL 3433
Score = 82.8 bits (203), Expect = 2e-15
Identities = 74/269 (27%), Positives = 106/269 (39%), Gaps = 73/269 (27%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P P+ +Q+L+ V G ++G P P++ W+ E ++L +T G +
Sbjct: 3236 PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEY 3294
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387
TL++ EAF +D YTC A N G
Sbjct: 3295 TLLLIEAFPEDAAVYTCEAKNDYGV----------------------------------- 3319
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKEL 447
TTS SL SV V +V SP + +PP L
Sbjct: 3320 -ATTSASL-------------------SVEVPEVVSPDQEM--------PVYPPAIITPL 3351
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
Q+T +EGQ +CRV G L+V W+ + +I+ S FR+ Q E+ L
Sbjct: 3352 QDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQF--------EDTYQLE 3402
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQL 536
IAE +PED G +T A N G +STA L
Sbjct: 3403 IAEAYPEDEGTYTFVASNAVGQVSSTANL 3431
Score = 82.4 bits (202), Expect = 2e-15
Identities = 187/867 (21%), Positives = 319/867 (36%), Gaps = 161/867 (18%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
P F +KL S + + ECR+T G+PT V W +GK L +++ E G +
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC-S 1761
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQK 388
L A+ D+G TC ATN G+D TSA + ++ D +SL +S+ +P+ +K
Sbjct: 1762 LDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK-------DEKSLVEESQ---LPEGRK 1811
Query: 389 KTTSVS--LTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKE 446
+ + TGVTT + +PD Y PV
Sbjct: 1812 GLQRIEELERMAHEGALTGVTTDQKEKQ---------------KPD--IVLYPEPV---- 1850
Query: 447 LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTL 506
V EG+ CRV G P +V W+ G I+ S FR+ + I L
Sbjct: 1851 ----RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV---------RYDGIHYL 1897
Query: 507 VIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPP 566
I + D G +A N G +L + E + P P
Sbjct: 1898 DIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI-----------QQREDFRSVLRRAPEPR 1946
Query: 567 PILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHP--SRGVNGLIN 624
P K E+Q+V+ P + + ++ AER T+ P S +
Sbjct: 1947 PEFHVHE---PGKLQFEVQKVDRP-VDTTETKEVVKLKRAERITHEKVPEESEELRSKFK 2002
Query: 625 GKANSNKSLPTPAVLLSPTKEP---PPLLAKPK---LGFPKKASRTARIASDEEIQGTKD 678
+ AV L K+ LL K K L + K+ + + A EE + T
Sbjct: 2003 RRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIP 2062
Query: 679 AVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQ-----EPEEETANQ 733
D K+ + P++ ER+ + +G S F ++ +PE E
Sbjct: 2063 TFKPD---KIELSPSM---EAPKIF--ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKN 2114
Query: 734 EYKVSSCE-------QRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHY 786
K+ + + + E+ R + + D + V+ ++ E F ++ K
Sbjct: 2115 GVKIERSDRIYWYWPEDNVCELVIR-DVTAEDSASIMVKAINIAGETSSHAFLLVQAKQL 2173
Query: 787 KIF-----------EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
F + TF C + P K+ W+KDG ++ + D Y + D
Sbjct: 2174 ITFTQELQDVVAKEKDTMATFECETS-EPFVKVKWYKDGMEVH-EGDKYRMHSDRKVHFL 2231
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
T T D + ++ + + T +L+V+
Sbjct: 2232 SILTIDTSDAEDYSCVLVEDE--NVKTTAKLIVEGA------------------------ 2265
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
F++ D+ V E ++C VS + W + ++ +
Sbjct: 2266 --------------VVEFVKELQDIEVPESYSGELECIVSP-ENIEGKWYHNDVELKSNG 2310
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK 1015
+ + R G +L ++ VT D G Y+ + + + K +P ++
Sbjct: 2311 KYTITSR-RGRQNLTVKDVTKEDQGEYSFVIDGK--------KTTCKLKMKPRPIAILQG 2361
Query: 1016 LQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGAT 1075
L + V +G V+LE +V + + W K+ + + S DRV + D ++ LLI+ T
Sbjct: 2362 LSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPS-DRVHIVIDKQSHM-LLIEDMT 2418
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDVY 1102
KEDAG Y+ + A +S + R+ VY
Sbjct: 2419 KEDAGNYSFTI--PALGLSTSGRVSVY 2443
Score = 82.0 bits (201), Expect = 3e-15
Identities = 68/266 (25%), Positives = 111/266 (41%), Gaps = 43/266 (16%)
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
EG P F CRV+G K+ W+ K+I P + + T L + +D+G Y
Sbjct: 3358 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPS--RFFRMTQFEDTYQLEIAEAYPEDEGTY 3414
Query: 850 TIMAANPQGRISCTGRLMVQAVNQ-------------------RGRSPRSPSG------- 883
T +A+N G++S T L ++A G S S
Sbjct: 3415 TFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGESEHSERDTRDAFSD 3474
Query: 884 -----HPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP 938
H + R SR S + P +F+P F Q V EG+ C++ P
Sbjct: 3475 SEDIDHKSMAAKRYASRISSTSSWP---EYFKPSFTQKLTFKYVLEGEPVVFTCRLIACP 3531
Query: 939 TPDLSWQLDGKPVRPDSAHKMLVRENGVH----SLIIEPVTSRDAGIYTCIATNRAGQNS 994
TP+++W + +P+ P +++ E+ +H SL I+ V RD+G Y +A N G
Sbjct: 3532 TPEMTWFHNNRPI-PTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAE 3590
Query: 995 FSLELVVAAK-EAHKPPVFIEKLQNT 1019
+ L+V K + K F+++ + T
Sbjct: 3591 STASLLVIQKGQDEKYLEFLKRAERT 3616
Score = 81.6 bits (200), Expect = 4e-15
Identities = 71/279 (25%), Positives = 119/279 (42%), Gaps = 37/279 (13%)
Query: 264 ALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL--HNTPDIQIHC 321
A+ P F++KL++ + EGSR+ ++ R TGNP P + W + H P I+I
Sbjct: 1549 AVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1608
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
G+ L I D+ YT A N +G DTT +V +E + F
Sbjct: 1609 TKGEA-ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-----------VEF----- 1651
Query: 382 AMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP 441
A P+ ++K + + G+ K + ++PL + Q L + P
Sbjct: 1652 AEPEPERK---LIIPRGTYRAKE-IAAPELEPLHLRYGQEQWEEGDLYDKEKQQ----KP 1703
Query: 442 VFTKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
F K+L + + ECR+ G P + V+W G ++ + R++ +
Sbjct: 1704 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINE------- 1756
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
C+L + D+GI TC A N YG+ ++A L+V
Sbjct: 1757 -FGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1794
Score = 81.6 bits (200), Expect = 4e-15
Identities = 66/224 (29%), Positives = 95/224 (42%), Gaps = 15/224 (6%)
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
M P F M + +KI E F C V G P P++ W+K+ I P + Y I + G+
Sbjct: 5378 MPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEE-KGSH 5436
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLM-----VQAVNQRGRSPRSPSGHPHVRR 889
+L L D Y A N G C G L + AV + +S + S
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAK-KSKVTLSSLMEELV 5495
Query: 890 PRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGK 949
+S DS E + ++ P F++ D G C V G P P + W DGK
Sbjct: 5496 LKSNYTDSFFEFQVVEG---PPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGK 5552
Query: 950 PVRPDSAHKMLVRENGV--HSLIIEPVTSRDAGIYTCIATNRAG 991
V+ + V E+G H+L I + D G Y C+ATN++G
Sbjct: 5553 LVQ---GRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSG 5593
Score = 79.0 bits (193), Expect = 2e-14
Identities = 63/240 (26%), Positives = 100/240 (41%), Gaps = 10/240 (4%)
Query: 772 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRD 829
E PFF+ KL ++ P F CR+ G+P + W DGK + + I
Sbjct: 1698 EKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEF 1757
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889
G CSL + D G T A N G + L+V+ + P G ++R
Sbjct: 1758 --GYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQR 1815
Query: 890 PRSRSRDSGDEN----EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQ 945
R + + Q+ +P + P + V EG+ R C+V+G P P ++W
Sbjct: 1816 IEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWY 1875
Query: 946 LDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
L+G+ +R + + VR +G+H L I S D G A N G ++L + +E
Sbjct: 1876 LNGQLIR--KSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1933
Score = 77.8 bits (190), Expect = 5e-14
Identities = 42/99 (42%), Positives = 63/99 (63%), Gaps = 8/99 (8%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP F + LQ+ V +G V L+ RV G P V+++R G+EIQ S DF+I Q+
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQE------- 155
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ +L+IAE +PED+G ++ +A N G ATSTA+L+V
Sbjct: 156 -GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 77.0 bits (188), Expect = 9e-14
Identities = 60/247 (24%), Positives = 94/247 (38%), Gaps = 39/247 (15%)
Query: 890 PRSRSRDSGDENEPIQERFFR--PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLD 947
P SR+ D+ I F P F+ D + E C V G+PTP++ W +
Sbjct: 5357 PNMDSREGEDKELKIDLEVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKE 5416
Query: 948 GKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQ--------------- 992
+ PD+ ++ E G H+L I V D+ Y C A N G+
Sbjct: 5417 YMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIF 5476
Query: 993 -----------NSFSLELVVAAKEAHK---------PPVFIEKLQNTGVADGYPVRLECR 1032
+S ELV+ + PP FI+ + + G +C
Sbjct: 5477 AVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCL 5536
Query: 1033 VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGI 1092
V G P P ++W K+ + + R ++ + G+ L I K D G Y A N++G+
Sbjct: 5537 VRGSPRPTVYWYKDGKLV--QGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGM 5594
Query: 1093 VSCTARL 1099
A L
Sbjct: 5595 AESFAAL 5601
Score = 75.1 bits (183), Expect = 3e-13
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 42/238 (17%)
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
P++ P + ++TV EG+ ++C +SG P+P ++W + + S +
Sbjct: 935 PVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIE-SSIDFQITF 993
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-------------- 1008
++G+ L+I + D+G +TC A N AG S S L V E +
Sbjct: 994 QSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEE 1053
Query: 1009 ---------------------------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQI 1041
P FI K + +G V C+V G P P +
Sbjct: 1054 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1113
Query: 1042 FWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
+WKK LT + G L+I +DAG YT+ +N+ G S +A L
Sbjct: 1114 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 75.1 bits (183), Expect = 3e-13
Identities = 72/292 (24%), Positives = 121/292 (41%), Gaps = 49/292 (16%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F + ++ +V E R EC V+ P V+W + +EL T I+I E +H L+I
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKY-VHRLLIP 3117
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTS 392
D G+YT +A G + ++A++F+EG + +S + +K+
Sbjct: 3118 STRMSDAGKYTVVA----GGNVSTAKLFVEG--------RDVRIRSIKKEVQVIEKQRAV 3165
Query: 393 VSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSP----------------------TSYLCR 430
V + I+ ++ VQ+ H T R
Sbjct: 3166 VEFEVNEDDVDAHWYKDGIE-INFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR 3224
Query: 431 PDGTTTAYF----PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
+ T Y PP +ELQ V G+ + G P ++ W+++ +
Sbjct: 3225 NRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFK 3284
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ L + +E TL++ E FPEDA ++TC A+NDYG AT++A L V
Sbjct: 3285 CKFLH-------DGQEY-TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3328
Score = 75.1 bits (183), Expect = 3e-13
Identities = 75/335 (22%), Positives = 130/335 (38%), Gaps = 66/335 (19%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F+Q++ SQEV EG C G P P V W+ + + IH + L
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIH-SLENYSILT 4002
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD---------------SDSESLA 375
++ + G TC+ N G+ T++ + ++ D + +L
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKVPVFHDYLDEEEELALV 4062
Query: 376 FKSRAGAMPQAQKK-----------------------TTSVSLTIGSSSP--------KT 404
F GA P ++ + V + + +++P K
Sbjct: 4063 FDQAKGAHPSMSQEGQTNLHLLKTNPPVPPSGDTELLSFPVEIQVTAATPIPEQDKESKE 4122
Query: 405 GVTTAVIQPLSVPVQQV-HSPTSYLCRPDGTTTAYFPPVFTKEL-QNTAVAEGQVVVLEC 462
T ++P ++P QV SP T PP +E+ ++ EG ++LEC
Sbjct: 4123 VFQTEELEPKAMPQDQVTQSPKHRFVFLSDITNE--PPKMLQEMPKHARCREGDSIILEC 4180
Query: 463 RVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI-CT--LVIAETFPEDAGIF 519
+ G P V WF+ G ++ + F+ EE+ C+ L I + +D+G +
Sbjct: 4181 LISGEPQPVVTWFQNGVLLKQNQKFQF-----------EEVNCSHQLYIKDVNSQDSGKY 4229
Query: 520 TCSARNDYGSATSTAQLVVTSAN-TENCSYESMGE 553
C A N+ G+ S + L V EN +E++GE
Sbjct: 4230 KCVAENNSGAVESVSDLTVEPVTYRENSQFENIGE 4264
Score = 74.3 bits (181), Expect = 6e-13
Identities = 78/323 (24%), Positives = 123/323 (38%), Gaps = 66/323 (20%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHN--TPDIQIHCEGGD 325
PAAP FI K Q++ EG V C+V GNP P V W G L + + + G+
Sbjct: 1079 PAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGE 1138
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ 385
L+I+ F DD G YT + N G + SA + E +D E L KS+ + Q
Sbjct: 1139 C-KLVISMTFADDAGEYTIVVRNKHGETSASASLLEE------ADYE-LLMKSQQEMLYQ 1190
Query: 386 AQKKTTSVSLTIGSSSP--------------------KTGVTTAVIQPL----------- 414
Q +G ++P K T V++
Sbjct: 1191 TQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSF 1250
Query: 415 ------SVPVQQVHSPTSYLCRPDG--------TTTAYFPPVFTKELQNTAVAEGQVVVL 460
+ + + + L DG + + F ++N + EG V
Sbjct: 1251 EERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTF 1310
Query: 461 ECRVRGAPPLQVQWFRQGSEIQDSPDFRI--LQKKPRSTAEPEEICTLVIAETFPEDAGI 518
C++ G P ++ W++ G I+ +++ LQ + +L I PED GI
Sbjct: 1311 HCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQ---------DGRASLRIPVVLPEDEGI 1361
Query: 519 FTCSARNDYGSATSTAQLVVTSA 541
+T A N G+A + +L V A
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPA 1384
Score = 73.9 bits (180), Expect = 8e-13
Identities = 60/269 (22%), Positives = 118/269 (43%), Gaps = 17/269 (6%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F ++++ + EG V C+++G P P++ W+ +GK + + Q+ +L I
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1352
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDS--ESLAFKSRAGAMPQAQKKT 390
+D G YT A+N G+ S ++++E A+ + + +L SR ++
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1412
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPD-GTTTAYFPPVFTKELQN 449
+ + ++ SP ++ A + P + SP L D + PVF + +
Sbjct: 1413 SPIRMSPARMSP-ARMSPARMSPARM------SPGRRLEETDESQLERLYKPVFVLKPVS 1465
Query: 450 TAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIA 509
EGQ + +V G P + WF G +I + +++ K+ + +L+I
Sbjct: 1466 FKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-------SLIIV 1518
Query: 510 ETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P D+G +T A+N G ++ + L V
Sbjct: 1519 PATPSDSGEWTVVAQNRAGRSSISVILTV 1547
Score = 73.6 bits (179), Expect = 1e-12
Identities = 71/291 (24%), Positives = 121/291 (41%), Gaps = 21/291 (7%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P I L+ +EG +CRV+G +V W+ + K++ + ++ + D + L
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRM-TQFEDTYQLE 3402
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
IAEA+ +D G YT +A+N G +++A + +E ES+ + + K+
Sbjct: 3403 IAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA-------PESILHERIEQEIEMEMKEL 3455
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTT--AYFPPVFTKELQ 448
S G S T + + Y R T++ YF P FT++L
Sbjct: 3456 FSE----GESEHSERDTRDAFSDSEDIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLT 3511
Query: 449 NTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE-PEEICTLV 507
V EG+ VV CR+ P ++ WF I L++ ++ ++ +L
Sbjct: 3512 FKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTG-----LRRIIKAESDLHHHSSSLE 3566
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDH 558
I D+G + A N GSA STA L+V + E + + H
Sbjct: 3567 IKRVQDRDSGSYRLLAINSEGSAESTASLLVIQKGQDEKYLEFLKRAERTH 3617
Score = 69.3 bits (168), Expect = 2e-11
Identities = 130/617 (21%), Positives = 224/617 (36%), Gaps = 117/617 (18%)
Query: 444 TKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
TK ++N V E + EC V P + W + G EI+ S F+I+ +
Sbjct: 2885 TKTMKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQG-------- 2933
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLV--------VTSANTENCSYESMGE 553
++ L+I T ED+ +T ND SAT T + + + + ++E
Sbjct: 2934 KLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVN 2993
Query: 554 SNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGV 613
++ I T ++ +KK + + N G +AA+
Sbjct: 2994 YEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFG----------DAADYT---- 3039
Query: 614 HPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPL--LAKPKLGFPKKASR----TARI 667
+ GKA S +L A + K + L K + F + S +
Sbjct: 3040 --------FVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWM 3091
Query: 668 ASDEEIQGTKDAVIQD---LERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVF--- 721
D+E+Q T IQ + R L + + G+ + ++ L + V
Sbjct: 3092 KDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRS 3151
Query: 722 ---NIQEPEEETANQEYKVSS-----------------CEQRLISEIEYRLERSPVDES- 760
+Q E++ A E++V+ ++R +E R+ R + E+
Sbjct: 3152 IKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETR 3211
Query: 761 -GDEVQYGDVPVENGMA----------PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIY 809
D +Y V N + P +L+ + G P F ++G P+PKI
Sbjct: 3212 QSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKIS 3271
Query: 810 WFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ 869
W+K+ + +S + + T L + +D YT A N G + + L V+
Sbjct: 3272 WYKEEQLLSTGFKCKFLHDGQEYTLLL--IEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3329
Query: 870 AVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCR 929
P V P D+ P+ + P + D EG+ R
Sbjct: 3330 V--------------PEVVSP--------DQEMPV----YPPAIITPLQDTVTSEGQPAR 3363
Query: 930 MDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR 989
C+VSG +SW K ++P +M E+ + L I D G YT +A+N
Sbjct: 3364 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGTYTFVASNA 3421
Query: 990 AGQNSFSLELVVAAKEA 1006
GQ S + L + A E+
Sbjct: 3422 VGQVSSTANLSLEAPES 3438
Score = 64.7 bits (156), Expect = 5e-10
Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Query: 1009 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
PP + L+N V +G V LEC + G P P + W +E+ + S D Q G
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQS--GIAR 999
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 1104
L+I+ A ED+G +T SA NEAG VS + L V +S
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 1035
Score = 63.5 bits (153), Expect = 1e-09
Identities = 71/275 (25%), Positives = 96/275 (34%), Gaps = 48/275 (17%)
Query: 267 FPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDL 326
F PRFI + ++ E S +C V G PTP V+W+ E + + E
Sbjct: 5376 FEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGS 5435
Query: 327 HTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQA 386
HTL I D+ Y C A N G E G T DSE A A
Sbjct: 5436 HTLKIRNVCLSDSATYRCRAVNCVG------EAICRG-FLTMGDSEIFAV--------IA 5480
Query: 387 QKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKE 446
+K ++S + K+ T + + Q V PP F K
Sbjct: 5481 KKSKVTLSSLMEELVLKSNYTDSFFE-----FQVVEG----------------PPRFIKG 5519
Query: 447 LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE--EIC 504
+ + G +C VRG+P V W++ G +Q R T E
Sbjct: 5520 ISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGR----------RFTVEESGTGFH 5569
Query: 505 TLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT 539
L I D G + C A N G A S A L +T
Sbjct: 5570 NLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/127 (31%), Positives = 66/127 (51%), Gaps = 4/127 (3%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT--PDIQIHCEGGDLH 327
AP F Q L+S V EGS E ++G P P V WF +G+ + + P +QI G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA- 63
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL-AFKSRAGAMPQA 386
L I + ++GRY+ ATN SG T++AE+ ++ ++ + + L + R G+ +
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 387 QKKTTSV 393
Q + T +
Sbjct: 124 QVRVTGI 130
Score = 61.2 bits (147), Expect = 5e-09
Identities = 67/328 (20%), Positives = 113/328 (34%), Gaps = 41/328 (12%)
Query: 770 PVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD 829
P +N M P F L K++E + F V G P P + W+++ + P D
Sbjct: 5176 PKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEP--DERIKMER 5233
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889
+ CSL + + G Y A N G + + +R + P H HV
Sbjct: 5234 VGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVM- 5292
Query: 890 PRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP--TPDLSWQLD 947
D R P + +L+ ++ K K+ +P TPD
Sbjct: 5293 -------EFDLEHTTSSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPEFTPD------ 5339
Query: 948 GKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAH 1007
HK + + S D + + N + EL + +
Sbjct: 5340 ---------HKSM-------------IVSLDVLPFNFVDPNMDSREGEDKELKIDLEVFE 5377
Query: 1008 KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 1067
PP FI + + + + +C V+G+P P++ W KE + + + ++ G
Sbjct: 5378 MPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEK-GSH 5436
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAGIVSC 1095
L I+ D+ Y A N G C
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEAIC 5464
Score = 60.5 bits (145), Expect = 9e-09
Identities = 93/478 (19%), Positives = 183/478 (38%), Gaps = 82/478 (17%)
Query: 672 EIQGTKDAVIQD-LERKLRFKEDLLN-NGQPRLTYEERMARRLLGADSATVFNIQEPEE- 728
EI+ +++A++++ L + + E L+N N Q R EE MA +G S + N+ E EE
Sbjct: 3805 EIRMSQEALVKESLPKDHLYGEILVNENTQARGQLEEIMANTTIGESSTYITNVCEKEEV 3864
Query: 729 -----------------------------ETANQEYKVSSCEQRLISEIEYRLERSPVDE 759
E A++ K + +S R++ ++
Sbjct: 3865 YETPENVSQAITPHASESFGTLVNVEESEEIASERIKKDDLRELQLSA-STRIDEFKTEQ 3923
Query: 760 SGDEVQYGDVPVENG---MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 816
+ +++ + P F +++ +++EG F C G P+P + W+ +
Sbjct: 3924 KEENMRFFENSFRKRPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMP 3983
Query: 817 ISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRG- 875
I P++ ++ I L+ L ++ ++G+ T + N G + T L V+A +
Sbjct: 3984 I-PRNQNFII-HSLENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDV 4041
Query: 876 RSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPG--DLTVQEGKLCRMDCK 933
++ + P H ++ DE E + F QA G QEG+
Sbjct: 4042 KAHKVPVFHDYL-----------DEEEELALVFD-----QAKGAHPSMSQEGQ------- 4078
Query: 934 VSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN 993
+L PV P ++L + P+ +D T
Sbjct: 4079 ------TNLHLLKTNPPVPPSGDTELLSFPVEIQVTAATPIPEQDKESKEVFQTEELEPK 4132
Query: 994 SFSLELVVAAKE---------AHKPPVFIEKL-QNTGVADGYPVRLECRVLGVPPPQIFW 1043
+ + V + + ++PP ++++ ++ +G + LEC + G P P + W
Sbjct: 4133 AMPQDQVTQSPKHRFVFLSDITNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTW 4192
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
+N L + + N + L I+ +D+G Y A+N +G V + L V
Sbjct: 4193 -FQNGVLLKQNQKFQFEEVNCSH-QLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTV 4248
Score = 54.3 bits (129), Expect = 6e-07
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 12/99 (12%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P F KL + EG PV FTCR+ P P++ WF + + I ++R + L
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPT-----GLRRIIKAESDL 3558
Query: 837 HTTASTLD-------DDGNYTIMAANPQGRISCTGRLMV 868
H +S+L+ D G+Y ++A N +G T L+V
Sbjct: 3559 HHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597
Score = 52.4 bits (124), Expect = 2e-06
Identities = 34/100 (34%), Positives = 46/100 (46%), Gaps = 10/100 (10%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDS--PDFRILQKKPRSTA 498
P FT+ LQ+ V EG E + G P +V WFR G I S P +I R+
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA-- 63
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L I ++G ++ A N G ATSTA+L+V
Sbjct: 64 ------KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 51.6 bits (122), Expect = 4e-06
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 25/271 (9%)
Query: 277 LRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE 336
+++ EV E EC V+ P + W G E+ + +I +G LH LII
Sbjct: 2888 MKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG-KLHQLIIMNTST 2945
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE---SLAFK---SRAGAMPQAQKKT 390
+D+ YT + N S T + + + D ++E ++ F+ + G + K
Sbjct: 2946 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 3005
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP---VFTKEL 447
+ T +T T + +V T + T T Y F K +
Sbjct: 3006 VEIKST-DKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHI 3064
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
++ V E + + EC V P + VQW + E+Q + +I ++K + L+
Sbjct: 3065 KDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEK--------YVHRLL 3115
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
I T DAG +T A G STA+L V
Sbjct: 3116 IPSTRMSDAGKYTVVA----GGNVSTAKLFV 3142
Score = 50.8 bits (120), Expect = 7e-06
Identities = 51/270 (18%), Positives = 102/270 (37%), Gaps = 28/270 (10%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP+ ++++SQ V +GS + RV G P P W+ G ++ + I + ++ L
Sbjct: 2077 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCEL 2136
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG----------ASSTDSDSESLAFKSR 379
+I + +D+ A N +G ++ A + ++ + +++A
Sbjct: 2137 VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFEC 2196
Query: 380 AGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC----RPDGTT 435
+ P + K + + + + LS+ Y C + T
Sbjct: 2197 ETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKT 2256
Query: 436 TAYF-----PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
TA F KELQ+ V E LEC V ++ +W+ E++ + + I
Sbjct: 2257 TAKLIVEGAVVEFVKELQDIEVPESYSGELECIV-SPENIEGKWYHNDVELKSNGKYTIT 2315
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFT 520
++ R L + + ED G ++
Sbjct: 2316 SRRGRQ--------NLTVKDVTKEDQGEYS 2337
Score = 50.4 bits (119), Expect = 9e-06
Identities = 45/162 (27%), Positives = 67/162 (41%), Gaps = 16/162 (9%)
Query: 229 EMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAA------PRFIQKLRSQEV 282
E E E R + D++D + H + + S + ++ P F QKL + V
Sbjct: 3458 EGESEHSERDTRDAFSDSED--IDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYV 3515
Query: 283 AEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH----TLIIAEAFEDD 338
EG V CR+ PTP + WF + + I E DLH +L I + D
Sbjct: 3516 LEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAE-SDLHHHSSSLEIKRVQDRD 3574
Query: 339 TGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRA 380
+G Y LA N GS ++A + + D + L F RA
Sbjct: 3575 SGSYRLLAINSEGSAESTASLLV---IQKGQDEKYLEFLKRA 3613
Score = 50.1 bits (118), Expect = 1e-05
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHS-TDRVSMHQDNHGYIC 1068
PVF+ K + +G R + +V+G P P+ FW + + + + T +V + +D G
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED--GTQS 1514
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISRH 1106
L+I AT D+G +TV A+N AG S + L V H
Sbjct: 1515 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH 1552
Score = 49.7 bits (117), Expect = 2e-05
Identities = 41/158 (25%), Positives = 67/158 (42%), Gaps = 5/158 (3%)
Query: 205 LSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSA 264
L P ++ +L S S+SP+ M SP AR + R+ S
Sbjct: 1396 LEPVSRIRSLSPRSVSRSPIR----MSPARMSP-ARMSPARMSPARMSPGRRLEETDESQ 1450
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
L P F+ K S + EG + +V G P P WF +G+++ N ++ +
Sbjct: 1451 LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED 1510
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+LII A D+G +T +A N +G + S + +E
Sbjct: 1511 GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1548
Score = 49.3 bits (116), Expect = 2e-05
Identities = 41/167 (24%), Positives = 69/167 (41%), Gaps = 22/167 (13%)
Query: 195 GESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDL----- 249
G + S DSG ++ + +++ ++D+ + E + P R Q ++L
Sbjct: 1765 GVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH 1824
Query: 250 -----AVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRW 304
V ++K +P L +P R V EG CRVTG P P+V W
Sbjct: 1825 EGALTGVTTDQKEKQKPDIVL-YPEPVR---------VLEGETARFRCRVTGYPQPKVNW 1874
Query: 305 FCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSG 351
+ G+ + + ++ +G +H L I + DTG A NP G
Sbjct: 1875 YLNGQLIRKSKRFRVRYDG--IHYLDIVDCKSYDTGEVKVTAENPEG 1919
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 4/126 (3%)
Query: 784 KHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTL 843
KH + EG + C ++G P+P + WF++G + K + +++ + L+
Sbjct: 4166 KHARCREGDSIILECLISGEPQPVVTWFQNG--VLLKQNQKFQFEEVNCSHQLYIKDVNS 4223
Query: 844 DDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEP 903
D G Y +A N G + L V+ V R S G + SR + D+ E
Sbjct: 4224 QDSGKYKCVAENNSGAVESVSDLTVEPVTYRENSQFENIG--EIYGKYSRDQQLQDQGES 4281
Query: 904 IQERFF 909
++ F+
Sbjct: 4282 VRAHFY 4287
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 12/138 (8%)
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRP-DSAHKMLVRENGVHSLIIE 972
LQ D V EG + +++ KVS L + + W DG+ V+P D H ++ +++ H L+IE
Sbjct: 2359 LQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQS--HMLLIE 2415
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
+T DAG Y+ +L L + + + I L++ V +G LEC+
Sbjct: 2416 DMTKEDAGNYSFTIP--------ALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECK 2467
Query: 1033 VLGVPPPQIFWKKENESL 1050
V + W +E +
Sbjct: 2468 VSVPDVTSVKWYLNDEQI 2485
Score = 45.8 bits (107), Expect = 2e-04
Identities = 63/291 (21%), Positives = 111/291 (38%), Gaps = 42/291 (14%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEG-GDLHTL 329
P FI+ L ++V E + + V G P P V+W+ L PD +I E G++ +L
Sbjct: 5183 PSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLE--PDERIKMERVGNVCSL 5240
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI--------------------------EG 363
I+ + + G Y C A N G + A V I
Sbjct: 5241 EISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHTT 5300
Query: 364 ASSTDSDSE-SLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSV--PVQQ 420
+S T S E L + + + +K+ V++ + K+ + + + P + P
Sbjct: 5301 SSRTPSPQEIVLEVELSEKDVKEFEKQVKIVTVPEFTPDHKSMIVSLDVLPFNFVDPNMD 5360
Query: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
+ D PP F + + + E V +C V G P +V+W+++
Sbjct: 5361 SREGEDKELKID-LEVFEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMC 5419
Query: 481 IQ-DSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSA 530
I+ D+ + I ++K T + +C D+ + C A N G A
Sbjct: 5420 IEPDNIKYVISEEKGSHTLKIRNVCL--------SDSATYRCRAVNCVGEA 5462
Score = 45.4 bits (106), Expect = 3e-04
Identities = 84/380 (22%), Positives = 138/380 (36%), Gaps = 77/380 (20%)
Query: 760 SGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISP 819
+G+ + G + V G L + E F C VA NP K W +DGK +
Sbjct: 2606 AGENMTSGKLTVAGGA---ISKPLTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPL 2661
Query: 820 KSDHYTIQRDLDG-TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
++ I+ + DG L A+ LDD G YT A + + +L V+AV +
Sbjct: 2662 TNN---IRSESDGHKRRLIIAATKLDDIGEYTYKVATSK----TSAKLKVEAVKIKKTLK 2714
Query: 879 R------------SPSGHPHVRRPR------------------------SRSRDSGDENE 902
HP+V+ + R ++ +E
Sbjct: 2715 NLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDE 2774
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL----DGKPV------- 951
+ FR L A L V+ K+ + V+ L +++++ D PV
Sbjct: 2775 SVYG--FRLGRLGASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSV 2832
Query: 952 --RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP 1009
+P H+ LV E VH L+++ ++ DAG YT + GQ +L V K
Sbjct: 2833 EIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVETLHITK- 2886
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
++N V + EC V P ++ K E ++ + H L
Sbjct: 2887 -----TMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQ---L 2938
Query: 1070 LIQGATKEDAGWYTVSAKNE 1089
+I + ED+ YT N+
Sbjct: 2939 IIMNTSTEDSAEYTFVCGND 2958
Score = 45.1 bits (105), Expect = 4e-04
Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 911 PHFLQA-PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
P LQ P +EG ++C +SG P P ++W +G ++ + + N H L
Sbjct: 4158 PKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQF-EEVNCSHQL 4216
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGY 1025
I+ V S+D+G Y C+A N +G +L V +P + E Q + + Y
Sbjct: 4217 YIKDVNSQDSGKYKCVAENNSGAVESVSDLTV------EPVTYRENSQFENIGEIY 4266
Score = 42.7 bits (99), Expect = 0.002
Identities = 59/256 (23%), Positives = 100/256 (39%), Gaps = 28/256 (10%)
Query: 277 LRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE 336
L Q VAE EC V NP + W +GK L T +I+ + G LIIA
Sbjct: 2626 LTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPLTNNIRSESD-GHKRRLIIAATKL 2683
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGA-------SSTDSDSESLAFKSRAGAMPQAQKK 389
DD G YT + TSA++ +E + T ++++ F P +
Sbjct: 2684 DDIGEYTYKV----ATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL-THPNVKGV 2738
Query: 390 TTSVSLTIGSSSPKTGVTT-AVIQPLSVPVQQVHSPTSY---LCRPDGTTTAYFPPV-FT 444
+ + S+ K ++ I L + + + Y L R + + V
Sbjct: 2739 QWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKII 2798
Query: 445 KELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
K+ ++ E V E V + V+WF + EI+ S R++ ++ ++
Sbjct: 2799 KKPKDVTALENATVAFEVSV-SHDTVPVKWFHKSVEIKPSDKHRLVSER--------KVH 2849
Query: 505 TLVIAETFPEDAGIFT 520
L++ P DAG +T
Sbjct: 2850 KLMLQNISPSDAGEYT 2865
Score = 42.7 bits (99), Expect = 0.002
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD--NHGYI 1067
P F +KL V +G PV CR++ P P++ W N + R+ + +H
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
L I+ D+G Y + A N G TA L
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASL 3595
Score = 42.0 bits (97), Expect = 0.003
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 7/125 (5%)
Query: 893 RSRDSGDENEPIQ--ERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
RS G NE I+ + P F++ V E +V GLP P + W +
Sbjct: 5163 RSDSFGTPNEAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSL 5222
Query: 951 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQ-NSFSLELVVAAKE---A 1006
+ PD KM R V SL I + + G Y C A N G+ SF+ ++ +E A
Sbjct: 5223 LEPDERIKM-ERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVA 5281
Query: 1007 HKPPV 1011
PPV
Sbjct: 5282 LPPPV 5286
Score = 41.2 bits (95), Expect = 0.005
Identities = 26/99 (26%), Positives = 41/99 (41%), Gaps = 8/99 (8%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP F +E+++ V EG C +G P V W+ I + +F I
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFII--------HS 3994
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
E L ++ ++ G TC N YG+ +T+ L V
Sbjct: 3995 LENYSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKV 4033
Score = 41.2 bits (95), Expect = 0.005
Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 4/102 (3%)
Query: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
+ K+ PP FIE L V + + V G+P P + W + N+SL +R+ M
Sbjct: 5174 IEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYR-NKSLLEPDERIKM- 5231
Query: 1061 QDNHGYICLL-IQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
+ G +C L I K + G Y A N G A +D+
Sbjct: 5232 -ERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 5272
Score = 40.0 bits (92), Expect = 0.012
Identities = 37/153 (24%), Positives = 63/153 (41%), Gaps = 14/153 (9%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP F + L V E + V G P V+W+R S ++ PD RI ++ +
Sbjct: 5182 PPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLE--PDERIKMERVGN--- 5236
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV------TSANTENCSYESMGE 553
+C+L I+ + G + C A N G A S A + + A +++ + E
Sbjct: 5237 ---VCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALPPPVTHQHVME 5293
Query: 554 SNNDHFQHFPPPPPILETSSLELASKKPSEIQQ 586
+ +H P P +EL+ K E ++
Sbjct: 5294 FDLEHTTSSRTPSPQEIVLEVELSEKDVKEFEK 5326
Score = 38.9 bits (89), Expect = 0.027
Identities = 63/282 (22%), Positives = 102/282 (36%), Gaps = 24/282 (8%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
I L+ V EG++ LEC+V+ V+W+ +++ +Q + G L+I
Sbjct: 2448 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK-GTKQRLVINR 2506
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASS-TDSDSESLAFK---SRAGAMPQAQ 387
D G Y + + S E I G T ++++++ F+ S +G
Sbjct: 2507 THASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWN 2566
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPV----F 443
K + SS I L+V Y T+ V
Sbjct: 2567 FKDKEIK----PSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAI 2622
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
+K L + VAE Q V EC V P + +W R G + L RS ++ +
Sbjct: 2623 SKPLTDQTVAESQEAVFECEVAN-PDSKGEWLRDGKHLP-------LTNNIRSESDGHK- 2673
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTEN 545
L+IA T +D G +T SA + V +N
Sbjct: 2674 RRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKN 2715
Score = 37.7 bits (86), Expect = 0.061
Identities = 50/218 (22%), Positives = 81/218 (37%), Gaps = 46/218 (21%)
Query: 783 LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 842
L K+ EG V +V+ + W KDG+++ P SD I D L T
Sbjct: 2362 LSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQP-SDRVHIVIDKQSHMLL-IEDMT 2418
Query: 843 LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENE 902
+D GNY+ P +S +GR+ V +V D
Sbjct: 2419 KEDAGNYSFTI--PALGLSTSGRVSVYSV---------------------------DVIT 2449
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
P++ D+ V EG ++CKVS + W L+ + ++PD + +V+
Sbjct: 2450 PLK-------------DVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK 2496
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 1000
L+I + D G Y I + S+E +
Sbjct: 2497 -GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKI 2533
Score = 32.0 bits (71), Expect = 3.3
Identities = 49/236 (20%), Positives = 90/236 (38%), Gaps = 26/236 (11%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+ I+ LR E V E ++ + V W + KE+ + +I G ++ L +
Sbjct: 2534 KIIRGLRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHG-KIYKLTV 2591
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGAS-------STDSDSESLAFKSRAGAMP 384
+DD G+YT A G + TS ++ + G + T ++S+ F+ A P
Sbjct: 2592 LNMMKDDEGKYTFYA----GENMTSGKLTVAGGAISKPLTDQTVAESQEAVFECEV-ANP 2646
Query: 385 QAQ----KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFP 440
++ + + LT S G +I + ++ Y + + T+
Sbjct: 2647 DSKGEWLRDGKHLPLTNNIRSESDGHKRRLI----IAATKLDDIGEYTYKVATSKTSAKL 2702
Query: 441 PV----FTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
V K L+N V E Q V + VQW + G ++ + + I K
Sbjct: 2703 KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVK 2758
Score = 30.8 bits (68), Expect = 7.4
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Query: 433 GTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
G + Y V T L++ V EG VLEC+V V+W+ +I+ PD R+ Q
Sbjct: 2438 GRVSVYSVDVITP-LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIK--PDDRV-QA 2493
Query: 493 KPRSTAEPEEICTLVIAETFPEDAG 517
+ T + LVI T D G
Sbjct: 2494 IVKGTKQ-----RLVINRTHASDEG 2513
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 270 bits (691), Expect = 4e-72
Identities = 197/724 (27%), Positives = 328/724 (45%), Gaps = 76/724 (10%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP L+N V EG+ V LEC + G P V W+R+ +I+ S DF+I +
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG----- 996
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHF 559
I L+I E F ED+G FTCSA N+ G+ +++ L V + ++ E
Sbjct: 997 ---IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEE 1053
Query: 560 QHFPPPPPILETSSL----ELASKKPSEIQQVNNP------ELGLSRAALQMQFNAAER- 608
+ F ++ T + + +P+ + P E G Q+ N
Sbjct: 1054 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1113
Query: 609 --ETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTAR 666
+ +GV + G ++ + + ++ + ++ + K G ++
Sbjct: 1114 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLE 1173
Query: 667 IASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTY---------EERMARRLLGADS 717
A E + ++ ++ + +E + P Y E+ + R+ + D+
Sbjct: 1174 EADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1233
Query: 718 ATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDE----SGDEVQYGDVPVEN 773
V E +QE+ +SS E+RLI EIEYR+ ++ ++E G+E D+
Sbjct: 1234 VVVRTYVE------DQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESE 1287
Query: 774 GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
+ F+ ++K+Y+I EGM VTF C+++G P PKI W+KDGK+I + Y + DG
Sbjct: 1288 AVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGR 1346
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR----------------S 877
SL +D+G YT A+N +G C+G+L V+ G S
Sbjct: 1347 ASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLS 1406
Query: 878 PRSPSGHPHVRRPRSRS-----------------RDSGDENEPIQERFFRPHFLQAPGDL 920
PRS S P P S R + +E ER ++P F+ P
Sbjct: 1407 PRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSF 1466
Query: 921 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 980
EG+ R D KV G P P+ W DG+ + D HK++++E+G SLII P T D+G
Sbjct: 1467 KCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSG 1526
Query: 981 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ 1040
+T +A NRAG++S S+ L V A E P+F+EKL+N + +G + ++ R G P P
Sbjct: 1527 EWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPD 1586
Query: 1041 IFWKKENESLT-HSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
I W K ++ + H ++ + + G L I +D+ WYT +A N+AG + ++
Sbjct: 1587 IVWLKNSDIIVPHKYPKIRI-EGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKV 1645
Query: 1100 DVYI 1103
+V +
Sbjct: 1646 NVEV 1649
Score = 162 bits (411), Expect = 1e-39
Identities = 217/872 (24%), Positives = 334/872 (38%), Gaps = 169/872 (19%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P FI+KL+ G+ V LECRV+G+ V WF +G E+ + P Q ++ TL
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQ-SSFSENVCTLN 6799
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE--------SLAFKSRAGA 382
++ DTG YTC+A N +GSD SA + ++ S + + SL F S
Sbjct: 6800 LSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRG 6859
Query: 383 MPQAQKKTTSVSL-TIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC------RPDGTT 435
P + K S + S + V + VQ + S Y C T
Sbjct: 6860 TPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLES-GDYSCLVTNDAGSASCT 6918
Query: 436 TAYF---PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
T F P F K L + +V G +VLE G PP+ V W + ++ I Q
Sbjct: 6919 THLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKD--------EYLISQS 6970
Query: 493 KPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMG 552
+ S E+ L I E+ ED ++C N+ G A + V
Sbjct: 6971 ERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSV-------------- 7016
Query: 553 ESNNDHFQHFPPPPPILETSSLELASKKPSEIQ--QVNNPELGL----------SRAALQ 600
PP I +E +P+ +Q PE+ + S A +
Sbjct: 7017 ---------LEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYK 7067
Query: 601 MQF--NAAERETNGVHPSRGVNGLINGKA-NSNKSLPTPAVLLSPTKEPPPLLAK----- 652
MQF N A N V S G + KA NS ++ + AVL+ ++ PP A+
Sbjct: 7068 MQFKNNVASLVINKVDHSD--VGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDV 7125
Query: 653 -PKLGFPKKASRTARIASDEEIQGT--KDAVIQDLERKLRFKEDLLNNGQPRLTYEERMA 709
LGFP + RI E +Q + KD V+ L ++ + ++ +A
Sbjct: 7126 HETLGFP--VAFECRINGSEPLQVSWYKDGVL------------LKDDANLQTSFVHNVA 7171
Query: 710 R-RLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGD 768
++L D + +I + +N SS + ++SE E
Sbjct: 7172 TLQILQTDQS---HIGQYNCSASNPLGTASSSAKLILSEHE------------------- 7209
Query: 769 VPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQR 828
+ PFF++K + G TF C V G KI W KD ++I P ++
Sbjct: 7210 ------VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTL- 7262
Query: 829 DLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVR 888
++ T +L D G YT A+N G+ SC+ +L VQ
Sbjct: 7263 -VENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ------------------- 7302
Query: 889 RPRSRSRDSGDENEPIQERFFRPHFL-QAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLD 947
EP P F+ + V++ + R +CK+ G P + W D
Sbjct: 7303 -------------EP-------PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKD 7342
Query: 948 GKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAH 1007
++ S +M ++ V L + ++ D+G YTC A N AG S S L V
Sbjct: 7343 ETEIQESSKFRMSFVDS-VAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV-----K 7396
Query: 1008 KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 1067
+PP+F +K G V LEC + G PP + W K+ L S + + +N
Sbjct: 7397 EPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKREL-RSGKKYKIMSENF-LT 7454
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
+ I D G Y A N+ G +C +
Sbjct: 7455 SIHILNVDAADIGEYQCKATNDVGSDTCVGSI 7486
Score = 159 bits (401), Expect = 2e-38
Identities = 192/858 (22%), Positives = 316/858 (36%), Gaps = 133/858 (15%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P FI+ L E G L+C+V G P R+ W+ E +L + P ++ + ++ +L+
Sbjct: 7020 PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKN-NVASLV 7078
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
I + D G Y+C A N G+ +SA + I+ + L P A +
Sbjct: 7079 INKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFECR 7138
Query: 391 TSVSLTIGSSSPKTGV--------------TTAVIQPLSVPVQQVHSPTSYLCRPDGTTT 436
+ S + S K GV A +Q L + P GT +
Sbjct: 7139 INGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTAS 7198
Query: 437 AY---------FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
+ PP F + + +A G+ +C V G P+++ W + EI+ ++
Sbjct: 7199 SSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNY 7258
Query: 488 RILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCS 547
++ E TL + + DAG +TC A N G + +AQL V
Sbjct: 7259 KMTLV--------ENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKK 7310
Query: 548 YESMGESNNDHFQHFPPP---PPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFN 604
E D F + P ++ L K +EIQ+ + + + ++ +
Sbjct: 7311 LEPSRIVKQDEFTRYECKIGGSPEIKV----LWYKDETEIQESSKFRMSFVDSVAVLEMH 7366
Query: 605 AAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRT 664
E +G + N G A+S+ SL KEPP KP P + +
Sbjct: 7367 NLSVEDSGDYTCEAHNAA--GSASSSTSLKV--------KEPPIFRKKPH---PIETLKG 7413
Query: 665 ARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMAR-RLLGADSATVFNI 723
A + + E+QGT + + K +L + + ++ E + +L D+A +
Sbjct: 7414 ADVHLECELQGTPPFHVS----WYKDKRELRSGKKYKIMSENFLTSIHILNVDAADI--- 7466
Query: 724 QEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKL 783
EY+ + ++ G + G + ++ P F KL
Sbjct: 7467 ---------GEYQCKA-----------------TNDVGSDTCVGSIALK--APPRFVKKL 7498
Query: 784 KHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTL 843
G V + G + WFKD +I +SD+ I + +L +
Sbjct: 7499 SDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYS-ENIATLQFSRVEP 7557
Query: 844 DDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEP 903
+ G YT N G C L V EP
Sbjct: 7558 ANAGKYTCQIKNDAGMQECFATLSVL--------------------------------EP 7585
Query: 904 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 963
++ P + V G C ++C V+G P W DGK + D+ +K+
Sbjct: 7586 AT-------IVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFF- 7637
Query: 964 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVAD 1023
N V L I V D+G+Y+ N G++S + L V+ + PP F KL+ T
Sbjct: 7638 NKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTV--PPSFTRKLKETNGLS 7695
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G V +EC+V G PP + W E ++ + DN L + + D+G YT
Sbjct: 7696 GSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDN--TCALTVNMLEESDSGDYT 7753
Query: 1084 VSAKNEAGIVSCTARLDV 1101
A N AG C+A L V
Sbjct: 7754 CIATNMAGSDECSAPLTV 7771
Score = 152 bits (385), Expect = 1e-36
Identities = 186/857 (21%), Positives = 330/857 (38%), Gaps = 137/857 (15%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F +KL + GS +++EC+V+G+ +WF +GKE+ + ++ C + +L
Sbjct: 5237 PSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSV-SLE 5295
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE---------GASSTDSDSESLAFKSRAG 381
+ +DT YTC +N +G D S + ++ G DS ++ FK+
Sbjct: 5296 VNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDS-TVEFKAILK 5354
Query: 382 AMPQAQKKTTSVSLTIGSSSPKTGV----TTAVIQPLSVPVQQVHSPTSYLCRP---DGT 434
P + K + + S PK + +T+ + SV + T ++ D
Sbjct: 5355 GTPPFKIKWFKDDVEL-VSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSC 5413
Query: 435 TTAYF---PPVFTKELQNTAVAE-GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
TT PP F K+L+ + + + G LEC++ G+P ++V WFR E+ S +R+
Sbjct: 5414 TTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRM- 5472
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYES 550
+ + + + ED+G F C A+N GS + + +++V
Sbjct: 5473 -------TFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPV------- 5518
Query: 551 MGESNNDHFQHFPPPPPILETSSL----ELASKKPSEIQQVNNPELGLSRAALQMQFNAA 606
F FPP L+ + + EL+ P E+ + S ++
Sbjct: 5519 --------FSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNF 5570
Query: 607 ERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTAR 666
+ ++ G + KA + T V KEPP ++K S T
Sbjct: 5571 HTSIHILNVDTSDIGEYHCKAQNEVGSDT-CVCTVKLKEPPRFVSKLN-------SLTVV 5622
Query: 667 IASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQP-RLTYEERMARRLLGADSATVFNIQE 725
E+Q + + + L+ KE+++ + R+T+ E +A +Q
Sbjct: 5623 AGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVA------------TLQF 5670
Query: 726 PEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKH 785
+ E AN + C+ + + + V E V+ K
Sbjct: 5671 AKAEPANAGKYI--CQIKNDGGMRENMATLMVLEPAVIVE----------------KAGP 5712
Query: 786 YKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDH-YTIQRDLDGTCSLHTTASTLD 844
+ G T C+VAG P+ + W+KDGK ++ H ++ + SL +
Sbjct: 5713 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKIS---SLRILSVERQ 5769
Query: 845 DDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPI 904
D G YT N G+ SCT + +
Sbjct: 5770 DAGTYTFQVQNNVGKSSCTAVV------------------------------------DV 5793
Query: 905 QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 964
+R P F + + G C ++CKV+G ++W + + + ++ +N
Sbjct: 5794 SDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDN 5853
Query: 965 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADG 1024
V +L + + S D G YTC+A N AG + L V +PP F+++ + V G
Sbjct: 5854 -VCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTV-----QEPPSFVKEPEPLEVLPG 5907
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
V + G PP ++ W + L DR +++ ++ L + +G YT
Sbjct: 5908 KNVTFTSVIRGTPPFKVNWFRGARELVKG-DRCNIYFED-TVAELELFNIDISQSGEYTC 5965
Query: 1085 SAKNEAGIVSCTARLDV 1101
N AG SCT RL V
Sbjct: 5966 VVSNNAGQASCTTRLFV 5982
Score = 150 bits (380), Expect = 5e-36
Identities = 194/845 (22%), Positives = 312/845 (36%), Gaps = 179/845 (21%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P P+ +Q+L+ V G ++G P P++ W+ E ++L +T G +
Sbjct: 3236 PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEY 3294
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387
TL++ EAF +D YTC A N G
Sbjct: 3295 TLLLIEAFPEDAAVYTCEAKNDYGV----------------------------------- 3319
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKEL 447
TTS SL SV V +V SP + +PP L
Sbjct: 3320 -ATTSASL-------------------SVEVPEVVSPDQEM--------PVYPPAIITPL 3351
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
Q+T +EGQ +CRV G L+V W+ + +I+ S FR+ Q E+ L
Sbjct: 3352 QDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQF--------EDTYQLE 3402
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPP 567
IAE +PED G +T A N G +STA L + + E+ +E + + + P
Sbjct: 3403 IAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP--ESILHERIEQEIEMEMKAAPVIKR 3460
Query: 568 ILETSSLELA--SKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGL--- 622
+E + L +K EIQ N +A ++ E + + S+ ++ L
Sbjct: 3461 KIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIY----ESDKCSIRSSKYISSLEIL 3516
Query: 623 ----------INGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEE 672
+N S+ A L PP L++PK + A+
Sbjct: 3517 RTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPK-SLTTFVGKAAKFICT-- 3573
Query: 673 IQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETAN 732
+ GT VI+ + +K + + P + + +L + T+
Sbjct: 3574 VTGTP--VIETIWQK----DGAALSPSPNWRISDAENKHILELSNLTI------------ 3615
Query: 733 QEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGM 792
Q+ V SC+ ++ G ++ ++ + + P F +L+ +
Sbjct: 3616 QDRGVYSCKAS--------------NKFGADICQAELIIID--KPHFIKELEPVQSAINK 3659
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
V C+V + K + W KDG+++ P D+ D T L + L D G Y
Sbjct: 3660 KVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIAT--LEIPLAKLKDSGTYVCT 3717
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A+N G SC+ + V R P P + P
Sbjct: 3718 ASNEAGSSSCSATVTV-------------------REP------------PSFVKKVDPS 3746
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
+L PG+ R+ CK+ G P ++W + K + + +M N L I
Sbjct: 3747 YLMLPGESA-------RLHCKLKGSPVIQVTWFKNNKELSESNTVRMYF-VNSEAILDIT 3798
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
V D+G Y+C A N G +S S E+V+ +PP FI+ L+ + G L+C
Sbjct: 3799 DVKVEDSGSYSCEAVNDVGSDSCSTEIVIK-----EPPSFIKTLEPADIVRGTNALLQCE 3853
Query: 1033 VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGI 1092
V G P +I W K+ + + S Q + +CL I D G Y NE G
Sbjct: 3854 VSGTGPFEISWFKDKKQIRSSKKYRLFSQKS--LVCLEIFSFNSADVGEYECVVANEVGK 3911
Query: 1093 VSCTA 1097
C A
Sbjct: 3912 CGCMA 3916
Score = 150 bits (378), Expect = 8e-36
Identities = 200/879 (22%), Positives = 336/879 (38%), Gaps = 165/879 (18%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F + ++ +V E R EC V+ P V+W + +EL T I+I E +H L+I
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKY-VHRLLIP 3117
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTS 392
D G+YT +A G + ++A++F+EG + +S + +K+
Sbjct: 3118 STRMSDAGKYTVVA----GGNVSTAKLFVEG--------RDVRIRSIKKEVQVIEKQRAV 3165
Query: 393 VSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSP----------------------TSYLCR 430
V + I+ ++ VQ+ H T R
Sbjct: 3166 VEFEVNEDDVDAHWYKDGIE-INFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR 3224
Query: 431 PDGTTTAYF----PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
+ T Y PP +ELQ V G+ + G P ++ W+++ +
Sbjct: 3225 NRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFK 3284
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENC 546
+ L + +E TL++ E FPEDA ++TC A+NDYG AT++A L V +
Sbjct: 3285 CKFLH-------DGQEY-TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSP 3336
Query: 547 SYESMGESNNDHFQHFPPPPPILETSSLELASKK--PSEIQ-QVNNPELGLS-------- 595
Q P PP + T + + + P+ Q +V+ +L +S
Sbjct: 3337 D------------QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKI 3384
Query: 596 -----------RAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTK 644
Q++ A E G + N + + +N SL P +L
Sbjct: 3385 KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHE-- 3442
Query: 645 EPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTY 704
RI + E++ VI+ RK+ E L + + T
Sbjct: 3443 ---------------------RIEQEIEMEMKAAPVIK---RKIEPLEVALGH-LAKFTC 3477
Query: 705 EERMARRLLGADSATVFNIQEPEEETANQEYKVSSCE---QRLISEIEYRLERSPVDESG 761
E + A + I E ++ + +SS E +++ EY + S +E G
Sbjct: 3478 EIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS--NEYG 3535
Query: 762 DEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKS 821
+ V P F + K F G F C V G P + W KDG +SP S
Sbjct: 3536 SVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSP-S 3594
Query: 822 DHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSP 881
++ I D + L + T+ D G Y+ A+N G C L++
Sbjct: 3595 PNWRIS-DAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII------------- 3640
Query: 882 SGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPD 941
+PHF++ + K ++C+V
Sbjct: 3641 --------------------------IDKPHFIKELEPVQSAINKKVHLECQVDEDRKVT 3674
Query: 942 LSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
++W DG+ + P +K+ E+ + +L I +D+G Y C A+N AG +S S + V
Sbjct: 3675 VTWSKDGQKLPPGKDYKICF-EDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 3733
Query: 1002 AAKEAHKPPVFIEKLQNTGVA-DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
+PP F++K+ + + G RL C++ G P Q+ W K N+ L+ S + V M+
Sbjct: 3734 -----REPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSES-NTVRMY 3787
Query: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
N I L I ED+G Y+ A N+ G SC+ +
Sbjct: 3788 FVNSEAI-LDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 3825
Score = 146 bits (369), Expect = 9e-35
Identities = 193/879 (21%), Positives = 327/879 (37%), Gaps = 147/879 (16%)
Query: 253 HNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELH 312
HN ++L P F +K E +G+ V+LEC + G P V W+ + +EL
Sbjct: 7381 HNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELR 7440
Query: 313 NTPDIQIHCEG--GDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEV-------FIEG 363
+ +I E +H L + A D G Y C ATN GSDT + F++
Sbjct: 7441 SGKKYKIMSENFLTSIHILNVDAA---DIGEYQCKATNDVGSDTCVGSIALKAPPRFVKK 7497
Query: 364 AS--STDSDSESLAFKSRAGAMP--------QAQKKTTSVSLTIGSSSPKTGVTTAVIQP 413
S ST E + GA P + + S ++ I S + + ++P
Sbjct: 7498 LSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEP 7557
Query: 414 LSVPVQQVHSPTSYLCRPD---------GTTTAYFPPVFTKELQNTAVAEGQVVVLECRV 464
+ Y C+ T + P ++ ++ V G LEC V
Sbjct: 7558 ANA--------GKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTV 7609
Query: 465 RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSAR 524
G P L +WF+ G E+ ++I + ++ L I P D+G+++ +
Sbjct: 7610 AGTPELSTKWFKDGKELTSDNKYKI--------SFFNKVSGLKIINVAPSDSGVYSFEVQ 7661
Query: 525 NDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELA-SKKPSE 583
N G + TA L V+ + E+N + + + ++ + +E
Sbjct: 7662 NPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNE 7721
Query: 584 IQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPT 643
I + L+ + N E +G + N A S++ V
Sbjct: 7722 ISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATN-----MAGSDECSAPLTV----- 7771
Query: 644 KEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLT 703
+EPP + KP P + ++GT + + +L+ + ++
Sbjct: 7772 REPPSFVQKPD---PMDVLTGTNVTFTSIVKGTPPFSVS----WFKGSSELVPGDRCNVS 7824
Query: 704 YEERMAR-RLLGADSATVFNIQEPEEET--ANQEYKVSSCEQRLISEIEYRLERSPVDES 760
E+ +A L D++ + E T + E +SC L + + +
Sbjct: 7825 LEDSVAELELFDVDTS------QSGEYTCIVSNEAGKASCTTHLYIKAPAKFVK------ 7872
Query: 761 GDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPK 820
+ D +E G I EG TFT G P + W K+G ++P
Sbjct: 7873 ----RLNDYSIEKGKP----------LILEG---TFT----GTPPISVTWKKNGINVTP- 7910
Query: 821 SDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRS 880
S I + + L +ST++D G Y N G+ SC+ ++++
Sbjct: 7911 SQRCNI-TTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILIL----------- 7958
Query: 881 PSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTP 940
EP P+F++ + V G + C+++G P
Sbjct: 7959 ---------------------EP-------PYFVKQLEPVKVSVGDSASLQCQLAGTPEI 7990
Query: 941 DLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 1000
+SW +RP + +KM R N V +L+ V D+G Y C A N G+ S S L
Sbjct: 7991 GVSWYKGDTKLRPTTTYKMHFR-NNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLT 8049
Query: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
V +E PP F +L++ G PV +C + G P + W K+ + L S + +
Sbjct: 8050 V--QEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSF 8107
Query: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
DN L I + AG Y+ +A N G S +ARL
Sbjct: 8108 LDNTA--TLNIFKTDRSLAGQYSCTATNPIGSASSSARL 8144
Score = 142 bits (358), Expect = 2e-33
Identities = 194/870 (22%), Positives = 314/870 (36%), Gaps = 167/870 (19%)
Query: 271 PRFIQKLR-SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
P F++K+ S + G L C++ G+P +V WF KEL + ++++ + L
Sbjct: 3737 PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEA-IL 3795
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ-- 387
I + +D+G Y+C A N GSD+ S E+ I+ S E A+ Q +
Sbjct: 3796 DITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVS 3855
Query: 388 ------------KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTT 435
KK S S K+ V + S V + + G
Sbjct: 3856 GTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCM 3915
Query: 436 TAYF---PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
+ PP F K++ + GQ V L+ VRG+ P+ V W + I++ ++
Sbjct: 3916 ATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKM--- 3972
Query: 493 KPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLV--------------- 537
+ + L+I + G +TC A N+ GS TS +L+
Sbjct: 3973 -----SFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQ 4027
Query: 538 VTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRA 597
VT+ + Y G P P L + K I NN
Sbjct: 4028 VTAGDPATLEYTVAGT---------PELKPKWYKDGRPLVASKKYRISFKNN-------- 4070
Query: 598 ALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGF 657
Q++F +AE +G + I+ + S+ T VL ++ P KP
Sbjct: 4071 VAQLKFYSAELHDSGQYTFE-----ISNEVGSSSCETTFTVL---DRDIAPFFTKPLRNV 4122
Query: 658 PKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADS 717
D+V+ NG RL ++ G+
Sbjct: 4123 --------------------DSVV---------------NGTCRLDC------KIAGSLP 4141
Query: 718 ATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPV--------DESGDEVQYGDV 769
V ++ +E A+ Y+++ E EI R++ + + G + G +
Sbjct: 4142 MRVSWFKDGKEIAASDRYRIAFVEGTASLEI-IRVDMNDAGNFTCRATNSVGSKDSSGAL 4200
Query: 770 PVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD 829
V+ P F K + G V G+ I WFK K++ Y +
Sbjct: 4201 IVQE--PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEA 4258
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889
L+ + L+ ++ D G YT +N G + C+ L V+
Sbjct: 4259 LESSLELYLVKTS--DSGTYTCKVSNVAGGVECSANLFVK-------------------- 4296
Query: 890 PRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGK 949
E E+ P L GD T ++ CKV+G P ++W + +
Sbjct: 4297 ----------EPATFVEKL-EPSQLLKKGDAT-------QLACKVTGTPPIKITWFANDR 4338
Query: 950 PVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP 1009
++ S H+M E+ L + V D+G Y C A N AG + S +V KE+
Sbjct: 4339 EIKESSKHRMSFVES-TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCS--SIVIVKES--- 4392
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
P F ++ + V Y V L V G PP +I W K+N L + QD+ + L
Sbjct: 4393 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDH--LVSL 4450
Query: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
I DAG Y NE G C+AR+
Sbjct: 4451 QILKFVAADAGEYQCRVTNEVGSSICSARV 4480
Score = 130 bits (326), Expect = 9e-30
Identities = 197/863 (22%), Positives = 315/863 (36%), Gaps = 143/863 (16%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F+ +L E A G V L+C+V G P V W+ +L TP+ + + ++ TL+
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTN-NVATLV 6137
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
+ +D+G YTC A N G+ ++ I+ S + L + +P
Sbjct: 6138 FNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCR 6197
Query: 391 TSVSLTIGSSSPKTGV---------TTAVIQPLSVPVQQVHSPTS--YLC---RPDGTT- 435
+ S I + GV T+ V ++ + Q S Y C P GT
Sbjct: 6198 LNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTAS 6257
Query: 436 -----TAYFP---PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
TA P P F + + V G+ EC V GA P+++ W + EI+ ++
Sbjct: 6258 SSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNY 6317
Query: 488 RI--LQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA---- 541
I + P L I + D+G +TC A ND G +AQL V
Sbjct: 6318 TITCVGNTPH----------LRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFV 6367
Query: 542 -NTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQ 600
E GES + P ++ S + SE+ + + +
Sbjct: 6368 KKLEASKVAKQGESIQLECKISGSPE--IKVSWF----RNDSELHESWKYNMSFINSVAL 6421
Query: 601 MQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKK 660
+ N A E +G + NG+ G A+ + +L K PP KP P
Sbjct: 6422 LTINEASAEDSGDYICEAHNGV--GDASCSTALTV--------KAPPVFTQKPS---PVG 6468
Query: 661 ASRTARIASDEEIQGTKD-AVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSAT 719
A + + + EI GT V+ +RK + R +++
Sbjct: 6469 ALKGSDVILQCEISGTPPFEVVWVKDRK-----------------QVRNSKK-------- 6503
Query: 720 VFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFF 779
F I +T+ + + + EY + + +E G + V + P F
Sbjct: 6504 -FKITSKHFDTSLHILNLEASDVG-----EYHCKAT--NEVGSDTCSCSVKFKE--PPRF 6553
Query: 780 EMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTT 839
KL G V V G + W KD ++ +S++ I +D +L
Sbjct: 6554 VKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISF-IDNIATLQLG 6612
Query: 840 ASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGD 899
+ + G Y N G C+ L V
Sbjct: 6613 SPEASNSGKYICQIKNDAGMRECSAVLTVL------------------------------ 6642
Query: 900 ENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKM 959
EP + ++ P +TV G ++C V+G P W DG+ + DS H +
Sbjct: 6643 --EPAR-------IIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHI 6693
Query: 960 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT 1019
N V SL I D G+Y+ N G+++ ++ + V+ + PP FI KL++
Sbjct: 6694 TFI-NKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIV--PPSFIRKLKDV 6750
Query: 1020 GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL-IQGATKED 1078
G V LECRV G P + W ++ + S +N +C L + D
Sbjct: 6751 NAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN---VCTLNLSLLEPSD 6807
Query: 1079 AGWYTVSAKNEAGIVSCTARLDV 1101
G YT A N AG C+A L V
Sbjct: 6808 TGIYTCVAANVAGSDECSAVLTV 6830
Score = 128 bits (321), Expect = 3e-29
Identities = 207/930 (22%), Positives = 343/930 (36%), Gaps = 188/930 (20%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P FI+K+ S G + + G+ V W + E+ +I++ E ++ +L
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFEN-NVASLY 4544
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASS----------TDSDSESLAFKSRA 380
++ G+Y C A N +G SA + ++ ++ T D +L K
Sbjct: 4545 LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSG 4604
Query: 381 GAMPQAQKKTTSVSLTIGSSSPKTGVT--TAVIQPLSVPVQQVHSPTSYLCRPDGTTTA- 437
A+ LT+GS K VT ++++ +S + T + G ++
Sbjct: 4605 TKEITAKWFKDGQELTLGSKY-KISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCK 4663
Query: 438 --------YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRI 489
PP FTK+L+ +G + LEC V G+ P+ +QWF+ EI S ++
Sbjct: 4664 ARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKF 4723
Query: 490 LQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYE 549
+ + L I++ D+G +TCSA N G + L V
Sbjct: 4724 --------SFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTV----------- 4764
Query: 550 SMGESNNDHFQHFPPPPPILETSSLEL----ASKKPSEIQQV-NNPEL--GLSRA----- 597
+F P + + ++L P I+ +N EL G +R+
Sbjct: 4765 ----KEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDD 4820
Query: 598 -ALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLG 656
+ ++ AA+ +G + + N + G A S +L KEPP + KP
Sbjct: 4821 TSTSLELFAAKATDSGTYICQLSNDV--GTATSKATL--------FVKEPPQFIKKPS-- 4868
Query: 657 FPKKASRTARIASDE-EIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGA 715
P R + + E +I GT K+R L N +T ++ +
Sbjct: 4869 -PVLVLRNGQSTTFECQITGTP---------KIRVSWYLDGN---EITAIQKHGISFI-- 4913
Query: 716 DSATVFNIQEPEEET-------ANQEYKVSSC--EQRLISEIEYRLERSPVDESGDEVQY 766
D F I E A + +SC E ++ + E PV + V+Y
Sbjct: 4914 DGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPV----EVVKY 4969
Query: 767 GDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTI 826
DV +E C V G P ++ W K+ ++I S YT+
Sbjct: 4970 SDVELE-------------------------CEVTGTPPFEVTWLKNNREIR-SSKKYTL 5003
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ--------------AVN 872
D +LH T D G Y + +N G SC+ R+ ++ +
Sbjct: 5004 -TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLK 5062
Query: 873 QRGRSPRSPSGHP-------------------------HVRRPRSRSRDSGD-------- 899
+ +G P V + RS D+G
Sbjct: 5063 SSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQA 5122
Query: 900 ENEPIQERFFRPHFLQAPGDLT-------VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
+NE ER + +Q P + V E ++C V+G P + W DGK +
Sbjct: 5123 KNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIV 5182
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF 1012
P S + + EN V S I+ V +D+G YT N G +S L V + + PP F
Sbjct: 5183 P-SRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVL--DQNIPPSF 5239
Query: 1013 IEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTD-RVSMHQDNHGYICLLI 1071
+KL G + +EC+V G P W K+ + ++ S R+ H+ + + L +
Sbjct: 5240 TKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERS---VSLEV 5296
Query: 1072 QGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
ED YT N AG +C+ L V
Sbjct: 5297 NNLELEDTANYTCKVSNVAGDDACSGILTV 5326
Score = 125 bits (313), Expect = 3e-28
Identities = 199/861 (23%), Positives = 310/861 (36%), Gaps = 145/861 (16%)
Query: 267 FPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDL 326
F + P ++ L++ EV+ LEC ++G P V W+ + ++L ++ +I + +
Sbjct: 5519 FSSFPPIVETLKNAEVS------LECELSGTPPFEVVWYKDKRQLRSSKKYKIASK--NF 5570
Query: 327 HTLI-IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAF--------- 376
HT I I D G Y C A N GSDT V ++ S SL
Sbjct: 5571 HTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQ 5630
Query: 377 KSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC--RPDG- 433
S GA P + I S + L + + Y+C + DG
Sbjct: 5631 ASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGG 5690
Query: 434 ------TTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
T P V ++ V G+ LEC+V G P L V+W++ G + S
Sbjct: 5691 MRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKH 5750
Query: 488 RILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCS 547
+ + +I +L I +DAG +T +N+ G ++ TA + V+
Sbjct: 5751 KF--------SFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSF 5802
Query: 548 YESMGESNNDHFQHFPPPPPILETSSL---ELASKKPSEIQQVNNPELGLSRAALQMQF- 603
+ + +L S + ++A P + + +S A Q F
Sbjct: 5803 TRRLKNTGG-----------VLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFS 5851
Query: 604 -NAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKAS 662
N + N + S + AN S AVL +EPP + +P+ P +
Sbjct: 5852 DNVCTLQLNSL-DSSDMGNYTCVAANVAGSDECRAVL--TVQEPPSFVKEPE---PLEVL 5905
Query: 663 RTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMAR-RLLGADSATVF 721
+ I+GT + R +L+ + + +E+ +A L D +
Sbjct: 5906 PGKNVTFTSVIRGTPPFKV----NWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSG 5961
Query: 722 NIQEPEEETANQEYKVSSCEQRL-ISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFE 780
A Q +SC RL + E L+R D VE G + E
Sbjct: 5962 EYTCVVSNNAGQ----ASCTTRLFVKEPAAFLKR-----------LSDHSVEPGKSIILE 6006
Query: 781 MKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQI--SPKSDHYTIQRDLDGTCSLHT 838
T+T G + W KDG I S K + T ++ TC L
Sbjct: 6007 S-------------TYT----GTLPISVTWKKDGFNITTSEKCNIVTTEK----TCILEI 6045
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
ST D G Y+ N GR C G L+ S P
Sbjct: 6046 LNSTKRDAGQYSCEIENEAGRDVC-GALV---------STLEP----------------- 6078
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHK 958
P+F+ L G + C+V+G P +SW +RP ++
Sbjct: 6079 ------------PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYR 6126
Query: 959 MLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQN 1018
N V +L+ V D+G YTC A N G + S + V +E PP F +L++
Sbjct: 6127 TYF-TNNVATLVFNKVNINDSGEYTCKAENSIG--TASSKTVFRIQERQLPPSFARQLKD 6183
Query: 1019 TGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKED 1078
G PV L CR+ G P Q+ W ++ L + + DN L I
Sbjct: 6184 IEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDN--VATLKILQTDLSH 6241
Query: 1079 AGWYTVSAKNEAGIVSCTARL 1099
+G Y+ SA N G S +ARL
Sbjct: 6242 SGQYSCSASNPLGTASSSARL 6262
Score = 121 bits (303), Expect = 4e-27
Identities = 176/854 (20%), Positives = 312/854 (36%), Gaps = 134/854 (15%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
+P F ++ + EV + V L V G P + WF + L + + + L +L
Sbjct: 4392 SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQD-HLVSL 4450
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL-AFKSRAGAMPQAQK 388
I + D G Y C TN GS SA V + S ES + + A K
Sbjct: 4451 QILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLK 4510
Query: 389 KTTSVSLTIGSSSPKTGVTTAV-------IQPLSVPVQQVHSPTSYLC---------RPD 432
+ +++T S + + + L + +V Y+C R
Sbjct: 4511 GSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCS 4570
Query: 433 GTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
+ P T+E + V +G L+ + G + +WF+ G E+ ++I
Sbjct: 4571 ALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKI--- 4627
Query: 493 KPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMG 552
+ + + L I T +D+G +T +ND G ++ A++ V + +
Sbjct: 4628 -----SVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLK 4682
Query: 553 ESNNDHFQHFPPPPPILETSSLELA-SKKPSEIQQVNNPELGLSRAALQMQFNAAERETN 611
+ ++ + + + + K EI + ++ + E +
Sbjct: 4683 KMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDS 4742
Query: 612 GVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDE 671
G + N KA N+ V KEPP + KP+ + + R+
Sbjct: 4743 GTYTCSATN-----KAGHNQCSGHLTV-----KEPPYFVEKPQ---SQDVNPNTRVQLKA 4789
Query: 672 EIQGTKDAVIQDLERKLRFKEDL-LNNGQPRLTYEERMARRL-----LGADSATVFNIQE 725
+ GT I+ FK++ L++G R +++ + L DS T
Sbjct: 4790 LVGGTAPMTIK------WFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLS 4843
Query: 726 PEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKH 785
+ TA + + E ++ + SPV + + NG + FE ++
Sbjct: 4844 NDVGTATSKATLFVKEPP-----QFIKKPSPV-----------LVLRNGQSTTFECQI-- 4885
Query: 786 YKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 845
G PK ++ W+ DG +I+ H +DG + + + +++
Sbjct: 4886 ---------------TGTPKIRVSWYLDGNEITAIQKHGI--SFIDGLATFQISGARVEN 4928
Query: 846 DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 905
G Y A N G SC+ L V+ EP
Sbjct: 4929 SGTYVCEARNDAGTASCSIELKVK--------------------------------EP-- 4954
Query: 906 ERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENG 965
P F++ + V + ++C+V+G P +++W + + +R + + R +
Sbjct: 4955 -----PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVS- 5008
Query: 966 VHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGY 1025
V +L I D G Y CI +N G S S VA KE PP FI+K++NT
Sbjct: 5009 VFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTR--VALKE---PPSFIKKIENTTTVLKS 5063
Query: 1026 PVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVS 1085
+ V G PP I W K+++ L + D+ L I+ +G YT
Sbjct: 5064 SATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDS--VATLQIRSVDNGHSGRYTCQ 5121
Query: 1086 AKNEAGIVSCTARL 1099
AKNE+G+ C A L
Sbjct: 5122 AKNESGVERCYAFL 5135
Score = 120 bits (302), Expect = 5e-27
Identities = 94/334 (28%), Positives = 142/334 (42%), Gaps = 47/334 (14%)
Query: 768 DVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ 827
++ +E AP + K++ ++ G FTC + P + WFK G++I +SD +I
Sbjct: 3447 EIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSI- 3504
Query: 828 RDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHV 887
R SL + + D G YT A+N G +SCT L V
Sbjct: 3505 RSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEA---------------- 3548
Query: 888 RRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLD 947
+ P FL P LT GK + C V+G P + WQ D
Sbjct: 3549 ---------------------YPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKD 3587
Query: 948 GKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAH 1007
G + P ++ EN H L + +T +D G+Y+C A+N+ G + EL++ K
Sbjct: 3588 GAALSPSPNWRISDAEN-KHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK--- 3643
Query: 1008 KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 1067
P FI++L+ A V LEC+V + W K+ + L D +D
Sbjct: 3644 --PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDK--IA 3699
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
L I A +D+G Y +A NEAG SC+A + V
Sbjct: 3700 TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 3733
Score = 119 bits (299), Expect = 1e-26
Identities = 196/916 (21%), Positives = 336/916 (36%), Gaps = 181/916 (19%)
Query: 213 ALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFP--AA 270
A+ S +SP E + + VKSP + + AV H P A
Sbjct: 32659 AVTSPPRVKSP-EPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAP 32717
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P+ Q L+++ E +++ + V W+ +GK+L Q H + L
Sbjct: 32718 PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 32777
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
I E D G Y C + G+ T+ + + S S+ ++ +KT
Sbjct: 32778 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKV------SKISETKKSDQKT 32831
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT 450
T ++T + PK +P+S PV LQ+T
Sbjct: 32832 TESTVT-RKTEPKAP------EPISSK-----------------------PVIVTGLQDT 32861
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
V+ V + G P W + G I +++ + K E I +
Sbjct: 32862 TVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE--------IHK 32913
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPPILE 570
T D+G++TC+ +N GS +S+ +L + + I +
Sbjct: 32914 TDTSDSGLYTCTVKNSAGSVSSSCKLTIKA---------------------------IKD 32946
Query: 571 TSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSN 630
T + +++++K SEI P+ +A +Q + S
Sbjct: 32947 TEAQKVSTQKTSEI----TPQ---KKAVVQEEI-------------------------SQ 32974
Query: 631 KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGT------KDAVIQDL 684
K+L + + +S K ++ KL ++AS ++ EE++ + K V +++
Sbjct: 32975 KALRSEEIKMSEAK------SQEKLALKEEAS---KVLISEEVKKSAATSLEKSIVHEEI 33025
Query: 685 ERKLRFKEDLLNNG-------QPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYK- 736
+ + E++ + Q + +R+ + A + V + E T ++EY+
Sbjct: 33026 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRY 33085
Query: 737 -VSSCEQRL-ISEIEYRLER-----SPVDESGDEVQYG-DVPVENGMAPFFEMKLKHYKI 788
VS +Q L I + +R E S E + QY + E AP F + + I
Sbjct: 33086 GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNI 33145
Query: 789 FEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGN 848
EG V FTC ++G P P+I WFK+ IS S + +I R + SL +++ D G
Sbjct: 33146 NEGQNVLFTCEISGEPSPEIEWFKNNLPIS-ISSNVSISRSRN-VYSLEIRNASVSDSGK 33203
Query: 849 YTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR--SRDSGDENEPIQE 906
YTI A N +G+ S T LMV P V P R SGD +
Sbjct: 33204 YTIKAKNFRGQCSATASLMVL---------------PLVEEPSREVVLRTSGDTS----- 33243
Query: 907 RFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGV 966
LQ + + + S + S + K SA M + +
Sbjct: 33244 -------LQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMK-FASMSAQSM----SSM 33291
Query: 967 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYP 1026
+E +S GI + Q S ++ A PP + + +G
Sbjct: 33292 QESFVEMSSSSFMGI------SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKV 33345
Query: 1027 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDN-HGYICLLIQGATKEDAGWYTVS 1085
+ + C G P P++ W + HS ++ H +N L+I K+D G YT+S
Sbjct: 33346 LTVACAFTGEPTPEVTWSCGGRKI-HSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLS 33404
Query: 1086 AKNEAGIVSCTARLDV 1101
NE G S T + +
Sbjct: 33405 LGNEFGSDSATVNIHI 33420
Score = 119 bits (298), Expect = 2e-26
Identities = 175/862 (20%), Positives = 307/862 (35%), Gaps = 148/862 (17%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P FI+ L ++ G+ L+C V+G + WF + K++ ++ ++ + +L+
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQ----KSLV 3886
Query: 331 IAEAFE---DDTGRYTCLATNPSGS-DTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQA 386
E F D G Y C+ N G + + E + + +A + + A
Sbjct: 3887 CLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAA 3946
Query: 387 QKKTTSVSLT-------IGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPD------- 432
+ + +S+T I + + L +P Q+ Y C +
Sbjct: 3947 VRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQT 4006
Query: 433 --GTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
G P + + V G LE V G P L+ +W++ G + S +RI
Sbjct: 4007 SVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRIS 4066
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYES 550
K + L D+G +T N+ GS S+ + T + + + +
Sbjct: 4067 FKN--------NVAQLKFYSAELHDSGQYTFEISNEVGS--SSCETTFTVLDRDIAPFFT 4116
Query: 551 MGESNNDHFQHFPPPPPILETSSLELAS---KKPSEIQQVNNPELGLSRAALQMQFNAAE 607
N D + SL + K EI + + ++ +
Sbjct: 4117 KPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVD 4176
Query: 608 RETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARI 667
G R N + G +S+ +L +EPP + KP K + +
Sbjct: 4177 MNDAGNFTCRATNSV--GSKDSSGALIV--------QEPPSFVTKPG---SKDVLPGSAV 4223
Query: 668 ASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLL--------GADSAT 719
QG+ I R + ++L++ G +T E + L G +
Sbjct: 4224 CLKSTFQGSTPLTI----RWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCK 4279
Query: 720 VFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFF 779
V N+ E +AN K E E +LE S + + GD Q
Sbjct: 4280 VSNVAGGVECSANLFVK----EPATFVE---KLEPSQLLKKGDATQ-------------- 4318
Query: 780 EMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTT 839
C+V G P KI WF + ++I S H ++ T L T
Sbjct: 4319 ----------------LACKVTGTPPIKITWFANDREIKESSKHR--MSFVESTAVLRLT 4360
Query: 840 ASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGD 899
++D G Y A N G C+ ++V+
Sbjct: 4361 DVGIEDSGEYMCEAQNEAGSDHCSSIVIVK------------------------------ 4390
Query: 900 ENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKM 959
P + F+P + D+ + +V+G P +++W D +R +K
Sbjct: 4391 -ESPYFTKEFKPIEVLKEYDVMLL--------AEVAGTPPFEITWFKDNTILRSGRKYKT 4441
Query: 960 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT 1019
++++ V SL I + DAG Y C TN G + S + + +PP FI+K+++T
Sbjct: 4442 FIQDHLV-SLQILKFVAADAGEYQCRVTNEVGSSICSARVTL-----REPPSFIKKIEST 4495
Query: 1020 GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 1079
G + + G P + W K+++ +T D + M +N+ L + G +
Sbjct: 4496 SSLRGGTAAFQATLKGSLPITVTWLKDSDEITED-DNIRMTFENN-VASLYLSGIEVKHD 4553
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G Y AKN+AGI C+A L V
Sbjct: 4554 GKYVCQAKNDAGIQRCSALLSV 4575
Score = 118 bits (295), Expect = 4e-26
Identities = 195/931 (20%), Positives = 327/931 (35%), Gaps = 162/931 (17%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
QP + H APR ++RS V G V PT V+W+ G EL + I
Sbjct: 32366 QPFTLDH---APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHY 32422
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSR 379
G L TL I + DD+G Y + TN G + A + + G T S+ +
Sbjct: 32423 TNTSGVL-TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVP 32481
Query: 380 AGAMPQAQ----------KKTTSVSLTIGSSSPKTGVT-----------TAVIQPLSVPV 418
P+ KKT+ + + K+ +T +A + S +
Sbjct: 32482 RSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 32541
Query: 419 QQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQG 478
++ R TT A + TK T V EG+ C G P V W R+G
Sbjct: 32542 EEKSLEEKSTTRKIKTTLA--ARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKG 32598
Query: 479 SEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ S ++ K +ST E I+ D G ++ N G + L +
Sbjct: 32599 QVLSTSARHQVTTTKYKSTFE--------ISSVQASDEGNYSVVVENSEGKQEAEFTLTI 32650
Query: 539 TSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQ---QVNNPELGLS 595
A + S PP + S E K P ++ +V +PE
Sbjct: 32651 QKARVTEKAVTS--------------PPRV---KSPEPRVKSPEAVKSPKRVKSPEPSHP 32693
Query: 596 RAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKL 655
+A V P+ K PT V P PP + K
Sbjct: 32694 KA---------------VSPTE------------TKPTPTEKVQHLPVSAPPKITQFLKA 32726
Query: 656 GFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMAR----- 710
K+ ++ + ++ + +D +KL+ + TYE ++
Sbjct: 32727 EASKEIAKLTCVVESSVLRAKEVTWYKD-GKKLKENGHFQFHYSADGTYELKINNLTESD 32785
Query: 711 ------RLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEV 764
+ G + N+Q + + KVS ISE + + ++ + +
Sbjct: 32786 QGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSK-----ISETK-KSDQKTTESTVTRK 32839
Query: 765 QYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHY 824
P P L+ + F + G P+P W KDGK I+ + Y
Sbjct: 32840 TEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT-QGGKY 32898
Query: 825 TIQRDLDG----------------TCSLHTTASTLDDDGNYTIMAAN------------- 855
+ D G TC++ +A ++ TI A
Sbjct: 32899 KLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTS 32958
Query: 856 ---PQGRISCTGRL-----------MVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDEN 901
PQ + + M +A +Q + + + + +S + E
Sbjct: 32959 EITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEK 33018
Query: 902 EPIQERF---------FRPH--FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
+ E R H +++ EG+ + ++G D+ W L+G
Sbjct: 33019 SIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVE 33076
Query: 951 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP 1010
+ ++ V + +L I+ + RD GI TCI+ + G +L ++ KE P
Sbjct: 33077 LTNSEEYRYGVSGSD-QTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS-KELSDAP 33134
Query: 1011 VFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
FI + ++ + +G V C + G P P+I W K N ++ S++ VS+ + + Y L
Sbjct: 33135 AFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN-VSISRSRNVY-SLE 33192
Query: 1071 IQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
I+ A+ D+G YT+ AKN G S TA L V
Sbjct: 33193 IRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223
Score = 117 bits (293), Expect = 6e-26
Identities = 187/875 (21%), Positives = 303/875 (34%), Gaps = 166/875 (18%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
PAA F+++L V G + LE TG V W +G + + I
Sbjct: 5985 PAA--FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTC- 6041
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVF----------IEGASSTDSDSESLAFK 377
L I + + D G+Y+C N +G D A V +E + DS SL +
Sbjct: 6042 ILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSL--Q 6099
Query: 378 SRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPD---GT 434
+ P+ + + T + L ++ Y C+ + GT
Sbjct: 6100 CQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGT 6159
Query: 435 TTA---------YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSP 485
++ PP F ++L++ G V L CR+ G+ P+QV W+R G ++D
Sbjct: 6160 ASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDE 6219
Query: 486 DFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA---- 541
+ + T+ + + TL I +T +G ++CSA N G+A+S+A+L
Sbjct: 6220 NLQ--------TSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSP 6271
Query: 542 --NTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQV----NNPELGLS 595
+ + S + + + D H P+ T S + +P + N P L +
Sbjct: 6272 FFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRIL 6331
Query: 596 RAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKL 655
+ +G +G +A ++ + LS KEPP + K
Sbjct: 6332 KV------------------GKGDSGQYTCQATNDVGKDMCSAQLS-VKEPPKFVKK--- 6369
Query: 656 GFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGA 715
+AS+ A+ E IQ LE K+ +G P +
Sbjct: 6370 ---LEASKVAK--QGESIQ---------LECKI--------SGSPEI------------- 6394
Query: 716 DSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEV-----QYGDVP 770
V + E + +Y +S + I + ++SGD + GD
Sbjct: 6395 ---KVSWFRNDSELHESWKYNMSFINSVALLTI----NEASAEDSGDYICEAHNGVGDAS 6447
Query: 771 VENGMA----PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTI 826
+ P F K +G V C ++G P ++ W KD KQ+
Sbjct: 6448 CSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKIT 6507
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH 886
+ D SLH D G Y A N G +C+ + +
Sbjct: 6508 SKHFD--TSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFK----------------- 6548
Query: 887 VRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL 946
EP P F++ D + G + V G + W
Sbjct: 6549 ---------------EP-------PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLK 6586
Query: 947 DGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 1006
D V +S + + + + +L + + ++G Y C N AG S L V
Sbjct: 6587 DRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVL---- 6642
Query: 1007 HKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGY 1066
+P IEK + V G P LEC V G P W K+ L S D +
Sbjct: 6643 -EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGREL--SADSKHHITFINKV 6699
Query: 1067 ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
L I A D G Y+ KN G +CT + V
Sbjct: 6700 ASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHV 6734
Score = 115 bits (289), Expect = 2e-25
Identities = 91/330 (27%), Positives = 146/330 (44%), Gaps = 46/330 (13%)
Query: 772 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD-L 830
E + P F +L+ + G+PV F C ++G+ + W+KDGK P D +Q L
Sbjct: 8052 EQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGK---PLKDSPNVQTSFL 8108
Query: 831 DGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRP 890
D T +L+ + G Y+ A NP G S + RL++ G++P
Sbjct: 8109 DNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILT----EGKNPP----------- 8153
Query: 891 RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
FF AP D V G+ +C V+G +SW D +
Sbjct: 8154 -----------------FFDIRL--APVDAVV--GESADFECHVTGTQPIKVSWAKDSRE 8192
Query: 951 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP 1010
+R +++ EN H +++ V D+G YTC A N G++S + +L + KE PP
Sbjct: 8193 IRSGGKYQISYLENSAHLTVLK-VDKGDSGQYTCYAVNEVGKDSCTAQLNI--KERLIPP 8249
Query: 1011 VFIEKLQNT-GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
F ++L T +G +LE RV G P + W K N + +++ ++N + L
Sbjct: 8250 SFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNT--LVL 8307
Query: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
++ A DAG YT N+AG CT+ +
Sbjct: 8308 QVRKAGMNDAGLYTCKVSNDAGSALCTSSI 8337
Score = 109 bits (273), Expect = 1e-23
Identities = 88/322 (27%), Positives = 139/322 (43%), Gaps = 27/322 (8%)
Query: 790 EGMPVTFTCRVAG-NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGN 848
EG V + C++ + ++ W+ +Q+ S+ Y I + DG L+ T DDG
Sbjct: 31581 EGGHVKYVCKIENYDQSTQVTWYFGVRQLE-NSEKYEITYE-DGVAILYVKDITKLDDGT 31638
Query: 849 YTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERF 908
Y N G S L V+ V + + RR + + D ++
Sbjct: 31639 YRCKVVNDYGEDSSYAELFVKGVRE--------VYDYYCRRTMKKIKRRTDTMRLLERP- 31689
Query: 909 FRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN--GV 966
P F + T G+ R ++ P P ++W G+ ++P K E+ G+
Sbjct: 31690 --PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGL 31747
Query: 967 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP-------VFIEKLQNT 1019
+ L I VT+ D YT +A N+ G++S +L V H PP +F L N
Sbjct: 31748 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTL---HPPPTDSTLRPMFKRLLANA 31804
Query: 1020 GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 1079
+G V E RV G+PPP + W+K+ + L+ + +H + Y L I+ ED
Sbjct: 31805 ECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH-EGLDYYALHIRDTLPEDT 31863
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G+Y V+A N AG SC A L V
Sbjct: 31864 GYYRVTATNTAGSTSCQAHLQV 31885
Score = 103 bits (258), Expect = 7e-22
Identities = 101/414 (24%), Positives = 174/414 (42%), Gaps = 61/414 (14%)
Query: 154 PKTPHQRKGGPQSQLCDKAANLIEELTSIFKAAKPRNRSPNGESSSPDSGYLSPKNQPSA 213
PKT H G ++ + A +++ S +A+ +S + P + + +P+
Sbjct: 824 PKTEH----GYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRV--RAEPTP 877
Query: 214 LLSASASQSPMEDQGEMEREVKSP---GARHCYQDNQDLAVPHNRKSHPQPHSALHFPAA 270
L + +P + E EVK + V H R++ + + P
Sbjct: 878 LPQFPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVE 937
Query: 271 -----PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGD 325
P + L++ V EG V LEC ++G P+P V W+ E ++ ++ D QI + G
Sbjct: 938 IPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG- 996
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ 385
+ L+I EAF +D+GR+TC A N +G+ +TS + ++ +
Sbjct: 997 IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ-------------------VSEE 1037
Query: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF--PPVF 443
+K+TT+V+ + + + V+ + S T P YF PV
Sbjct: 1038 FEKETTAVTEKFTTEEKRFVESRDVVMTDT-------SLTEEQAGPGEPAAPYFITKPVV 1090
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
K + EG VV C+V G P V W + G + +++ K T E
Sbjct: 1091 QK------LVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNK--QTGE---- 1138
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNND 557
C LVI+ TF +DAG +T RN +G +++A L+ E YE + +S +
Sbjct: 1139 CKLVISMTFADDAGEYTIVVRNKHGETSASASLL------EEADYELLMKSQQE 1186
Score = 103 bits (258), Expect = 7e-22
Identities = 97/385 (25%), Positives = 153/385 (39%), Gaps = 64/385 (16%)
Query: 730 TANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMA------------- 776
T +Q +++ E+ I EI S V+++G Y +EN
Sbjct: 7909 TPSQRCNITTTEKSAILEIP----SSTVEDAGQYNCY----IENASGKDSCSAQILILEP 7960
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P+F +L+ K+ G + C++AG P+ + W+K ++ P + + R+ +L
Sbjct: 7961 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRN--NVATL 8018
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
++D G Y A N G +S + L VQ + P S SR
Sbjct: 8019 VFNQVDINDSGEYICKAENSVGEVSASTFLTVQ----------------EQKLPPSFSRQ 8062
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956
D E + G DC +SG +SW DGKP++ DS
Sbjct: 8063 LRDVQETV--------------------GLPVVFDCAISGSEPISVSWYKDGKPLK-DSP 8101
Query: 957 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
+ + +L I AG Y+C ATN G S S L++ E PP F +L
Sbjct: 8102 NVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILT--EGKNPPFFDIRL 8159
Query: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 1076
G EC V G P ++ W K++ + + +N ++ +L K
Sbjct: 8160 APVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVL--KVDK 8217
Query: 1077 EDAGWYTVSAKNEAGIVSCTARLDV 1101
D+G YT A NE G SCTA+L++
Sbjct: 8218 GDSGQYTCYAVNEVGKDSCTAQLNI 8242
Score = 103 bits (256), Expect = 1e-21
Identities = 179/858 (20%), Positives = 304/858 (35%), Gaps = 146/858 (17%)
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
+ AAP +K+ EVA G C + P R +WF G+E++ + I
Sbjct: 3450 MEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR-SSK 3508
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMP 384
+ +L I D G YTC A+N GS + +A + T +++ F SR ++
Sbjct: 3509 YISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL-------TVTEAYPPTFLSRPKSLT 3561
Query: 385 QAQKKTTSVSLTIG----------------SSSPKTGVTTAVIQP-LSVPVQQVHSPTSY 427
K T+ S SP ++ A + L + + Y
Sbjct: 3562 TFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVY 3621
Query: 428 LCRPDGTTTAYF---------PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQG 478
C+ A P F KEL+ A + V LEC+V + V W + G
Sbjct: 3622 SCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDG 3681
Query: 479 SEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ D++I + ++I TL I +D+G + C+A N+ GS++ +A + V
Sbjct: 3682 QKLPPGKDYKICFE--------DKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 3733
Query: 539 ----TSANTENCSYESM-GESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELG 593
+ + SY + GES H + P+++ + K E+ + N +
Sbjct: 3734 REPPSFVKKVDPSYLMLPGESARLHCK--LKGSPVIQVTWF----KNNKELSESNTVRMY 3787
Query: 594 LSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKP 653
+ + + E +G + VN + + S T V+ KEPP +
Sbjct: 3788 FVNSEAILDITDVKVEDSGSYSCEAVNDV------GSDSCSTEIVI----KEPPSFI--- 3834
Query: 654 KLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLL 713
K P R E+ GT I + K+ + ++ + RL ++ + L
Sbjct: 3835 KTLEPADIVRGTNALLQCEVSGTGPFEIS----WFKDKKQIRSSKKYRLFSQKSLV--CL 3888
Query: 714 GADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVEN 773
S ++ E E AN+ K L+ E
Sbjct: 3889 EIFSFNSADVGEYECVVANEVGKCGCMATHLLKE-------------------------- 3922
Query: 774 GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
P F K+ G VT V G+ + W K + I + D +G
Sbjct: 3923 --PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVI--REDGKIKMSFSNGV 3978
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR 893
L + G YT +A N G + G L+V+
Sbjct: 3979 AVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVK------------------------ 4014
Query: 894 SRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRP 953
EP + ++ + V G ++ V+G P W DG+P+
Sbjct: 4015 --------EPAK-------IIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVA 4059
Query: 954 DSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI 1013
+++ + N V L D+G YT +N G +S V ++ P F
Sbjct: 4060 SKKYRISFK-NNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDI--APFFT 4116
Query: 1014 EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQG 1073
+ L+N RL+C++ G P ++ W K+ + + ++DR + G L I
Sbjct: 4117 KPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIA-ASDRYRI-AFVEGTASLEIIR 4174
Query: 1074 ATKEDAGWYTVSAKNEAG 1091
DAG +T A N G
Sbjct: 4175 VDMNDAGNFTCRATNSVG 4192
Score = 101 bits (252), Expect = 3e-21
Identities = 65/191 (34%), Positives = 102/191 (53%), Gaps = 7/191 (3%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR-ENGVHSL 969
P F Q + V EG + +SG P P++SW DG+ + + + + +G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
I VT ++G Y+ ATN +GQ + + EL+V A+ A PP F+++LQ+ V G VRL
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA--PPNFVQRLQSMTVRQGSQVRL 123
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTD-RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
+ RV G+P P + + ++ + S D ++S D + LLI A ED+G Y+V+A N
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS---LLIAEAYPEDSGTYSVNATN 180
Query: 1089 EAGIVSCTARL 1099
G + TA L
Sbjct: 181 SVGRATSTAEL 191
Score = 99.4 bits (246), Expect = 2e-20
Identities = 85/319 (26%), Positives = 136/319 (42%), Gaps = 33/319 (10%)
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
EG P F CRV+G K+ W+ K+I P + + T L + +D+G Y
Sbjct: 3358 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPS--RFFRMTQFEDTYQLEIAEAYPEDEGTY 3414
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 909
T +A+N G++S T L ++A P H R + + + P+ +R
Sbjct: 3415 TFVASNAVGQVSSTANLSLEA----------PESILHERIEQEIEMEM--KAAPVIKRKI 3462
Query: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENG-VHS 968
P L V G L + C++ P W G+ + + K +R + + S
Sbjct: 3463 EP--------LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIY--ESDKCSIRSSKYISS 3512
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
L I D G YTC A+N G S + L V EA+ PP F+ + ++ G +
Sbjct: 3513 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT--EAY-PPTFLSRPKSLTTFVGKAAK 3569
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTD-RVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 1087
C V G P + W+K+ +L+ S + R+S ++ H L + T +D G Y+ A
Sbjct: 3570 FICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKH---ILELSNLTIQDRGVYSCKAS 3626
Query: 1088 NEAGIVSCTARLDVYISRH 1106
N+ G C A L + H
Sbjct: 3627 NKFGADICQAELIIIDKPH 3645
Score = 97.4 bits (241), Expect = 6e-20
Identities = 159/726 (21%), Positives = 265/726 (36%), Gaps = 133/726 (18%)
Query: 444 TKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
TK ++N V E + EC V P + W + G EI+ S F+I+ +
Sbjct: 2885 TKTMKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQG-------- 2933
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLV--------VTSANTENCSYESMGE 553
++ L+I T ED+ +T ND SAT T + + + + ++E
Sbjct: 2934 KLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVN 2993
Query: 554 SNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGV 613
++ I T ++ +KK + + N G +AA+
Sbjct: 2994 YEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFG----------DAADYT---- 3039
Query: 614 HPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPL--LAKPKLGFPKKASR----TARI 667
+ GKA S +L A + K + L K + F + S +
Sbjct: 3040 --------FVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWM 3091
Query: 668 ASDEEIQGTKDAVIQD---LERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVF--- 721
D+E+Q T IQ + R L + + G+ + ++ L + V
Sbjct: 3092 KDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRS 3151
Query: 722 ---NIQEPEEETANQEYKVSS-----------------CEQRLISEIEYRLERSPVDES- 760
+Q E++ A E++V+ ++R +E R+ R + E+
Sbjct: 3152 IKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETR 3211
Query: 761 -GDEVQYGDVPVENGMA----------PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIY 809
D +Y V N + P +L+ + G P F ++G P+PKI
Sbjct: 3212 QSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKIS 3271
Query: 810 WFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ 869
W+K+ + +S + + T L + +D YT A N G + + L V+
Sbjct: 3272 WYKEEQLLSTGFKCKFLHDGQEYTLLL--IEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3329
Query: 870 AVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCR 929
P V P D+ P+ + P + D EG+ R
Sbjct: 3330 V--------------PEVVSP--------DQEMPV----YPPAIITPLQDTVTSEGQPAR 3363
Query: 930 MDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR 989
C+VSG +SW K ++P +M E+ + L I D G YT +A+N
Sbjct: 3364 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGTYTFVASNA 3421
Query: 990 AGQNSFSLELVVAAKEA--------------HKPPVFIEKLQNTGVADGYPVRLECRVLG 1035
GQ S + L + A E+ PV K++ VA G+ + C +
Sbjct: 3422 VGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQS 3481
Query: 1036 VPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSC 1095
P + W K + + +D+ S+ + L I D G YT A NE G VSC
Sbjct: 3482 APNVRFQWFKAGREI-YESDKCSIRSSKY-ISSLEILRTQVVDCGEYTCKASNEYGSVSC 3539
Query: 1096 TARLDV 1101
TA L V
Sbjct: 3540 TATLTV 3545
Score = 96.7 bits (239), Expect = 1e-19
Identities = 87/327 (26%), Positives = 131/327 (40%), Gaps = 53/327 (16%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQI--SPKSDHYTIQRDLDGTC 834
P F KLK G V CRV+G+ + WF+DG +I PK + C
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQ----SSFSENVC 6796
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 894
+L+ + D G YT +AAN G C+ L VQ
Sbjct: 6797 TLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ------------------------- 6831
Query: 895 RDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
EP P F Q P + V G + G P + W + + P
Sbjct: 6832 -------EP-------PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPG 6877
Query: 955 SAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIE 1014
+ + + E+ V L + V ++G Y+C+ TN AG S + L V +P F++
Sbjct: 6878 ESCNISL-EDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVK-----EPATFVK 6931
Query: 1015 KLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGA 1074
+L + V G P+ LE G PP + W K+ E L ++R S+ I +++ +
Sbjct: 6932 RLADFSVETGSPIVLEATYTGTPPISVSWIKD-EYLISQSERCSITMTEKSTILEILE-S 6989
Query: 1075 TKEDAGWYTVSAKNEAGIVSCTARLDV 1101
T ED Y+ +NEAG C A + V
Sbjct: 6990 TIEDYAQYSCLIENEAGQDICEALVSV 7016
Score = 95.9 bits (237), Expect = 2e-19
Identities = 95/393 (24%), Positives = 151/393 (38%), Gaps = 92/393 (23%)
Query: 759 ESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQIS 818
E DE Q +E P F +K +K EG F +V G P P+ +WF DG+QI
Sbjct: 1444 EETDESQ-----LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV 1498
Query: 819 PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
H + ++ DGT SL +T D G +T++A N GR S + L V+AV
Sbjct: 1499 NDYTHKVVIKE-DGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV------- 1550
Query: 879 RSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP 938
E +P F++ ++ ++EG M + +G P
Sbjct: 1551 ---------------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1583
Query: 939 TPDLSWQLDGKPVRPDSAHKMLVR-ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSL 997
PD+ W + + P K+ + G +L I+ S+D+ YT A N+AG+++
Sbjct: 1584 NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1643
Query: 998 ELVVAA-----------------------------------------------KEAHKPP 1010
++ V KE + P
Sbjct: 1644 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1703
Query: 1011 VFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
F +KL + + P ECR+ +G P + W + + L + +R+ M + GY
Sbjct: 1704 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPL-EAANRLRMINE-FGYCS 1761
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
L A D+G T A N+ G +A L V
Sbjct: 1762 LDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1794
Score = 95.1 bits (235), Expect = 3e-19
Identities = 79/325 (24%), Positives = 128/325 (39%), Gaps = 49/325 (15%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P F K + G VTFT V G P + WFK ++ P D + + D L
Sbjct: 7775 PSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVP-GDRCNVSLE-DSVAEL 7832
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
G YT + +N G+ SCT L ++A +
Sbjct: 7833 ELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAK----------------------- 7869
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956
F++ D ++++GK ++ +G P ++W+ +G V P
Sbjct: 7870 ----------------FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQR 7913
Query: 957 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
+ E L I T DAG Y C N +G++S S ++++ +PP F+++L
Sbjct: 7914 CNITTTEKSA-ILEIPSSTVEDAGQYNCYIENASGKDSCSAQILIL-----EPPYFVKQL 7967
Query: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 1076
+ V+ G L+C++ G P + W K + L T MH N+ L+
Sbjct: 7968 EPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKL-RPTTTYKMHFRNN-VATLVFNQVDI 8025
Query: 1077 EDAGWYTVSAKNEAGIVSCTARLDV 1101
D+G Y A+N G VS + L V
Sbjct: 8026 NDSGEYICKAENSVGEVSASTFLTV 8050
Score = 93.6 bits (231), Expect = 9e-19
Identities = 71/296 (23%), Positives = 129/296 (43%), Gaps = 31/296 (10%)
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
L+ A +F+++L + +G + LE TG P V W G ++ TP + +
Sbjct: 7862 LYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNG--INVTPSQRCNITTT 7919
Query: 325 DLHTLI-IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAM 383
+ ++ I + +D G+Y C N SG D+ SA++ I E + A
Sbjct: 7920 EKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSAS 7979
Query: 384 PQAQ-KKTTSVSLTIGSSSPKTGVTTAV-------IQPLSVPVQQVHSPTSYLCRPDGTT 435
Q Q T + ++ K TT + L ++ Y+C+ + +
Sbjct: 7980 LQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSV 8039
Query: 436 ------------TAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQD 483
PP F+++L++ G VV +C + G+ P+ V W++ G ++D
Sbjct: 8040 GEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKD 8099
Query: 484 SPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT 539
SP+ + T+ + TL I +T AG ++C+A N GSA+S+A+L++T
Sbjct: 8100 SPNVQ--------TSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILT 8147
Score = 93.2 bits (230), Expect = 1e-18
Identities = 68/261 (26%), Positives = 116/261 (44%), Gaps = 43/261 (16%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F L+ + EG TF ++G P P++ WF+DG+ IS + DG
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
L A T + G Y++ A N G+ + T L+V+A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------------------------- 99
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
E P P+F+Q +TV++G R+ +V+G+PTP + + DG ++ S
Sbjct: 100 ----ETAP-------PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQ-SS 147
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---AHKPPVF 1012
+ +E ++SL+I D+G Y+ ATN G+ + + EL+V +E A K
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 1013 IEKLQNTGVADGYPVRLECRV 1033
+ Q +++ R+E ++
Sbjct: 208 VSTAQ---ISESRQTRIEKKI 225
Score = 89.4 bits (220), Expect = 2e-17
Identities = 131/629 (20%), Positives = 238/629 (37%), Gaps = 76/629 (12%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F+++L +V+ G L+C++ G P V W+ +L T ++H ++ TL+
Sbjct: 7961 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRN-NVATLV 8019
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
+ +D+G Y C A N G + S + ++ S S L +P
Sbjct: 8020 FNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCA 8079
Query: 391 TSVSLTIGSSSPKTG--------VTTAVIQ---PLSVPVQQVHSPTSYLC---RPDGT-- 434
S S I S K G V T+ + L++ Y C P G+
Sbjct: 8080 ISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSAS 8139
Query: 435 -------TTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
T PP F L G+ EC V G P++V W + EI+ +
Sbjct: 8140 SSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKY 8199
Query: 488 RILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL-----VVTSAN 542
+I + E L + + D+G +TC A N+ G + TAQL ++ +
Sbjct: 8200 QI--------SYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSF 8251
Query: 543 TENCSYESMGESNNDHFQHFPPPPPILETSSLELA-SKKPSEIQQVNNPELGLSRAALQM 601
T+ S E++ E+ + F+ + + + +A K EIQ +N E+ L +
Sbjct: 8252 TKRLS-ETVEETEGNSFK---LEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVL 8307
Query: 602 QFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKA 661
Q A G++ + N ++ +L T ++++ K+PP + P
Sbjct: 8308 QVRKAGMNDAGLYTCKVSN-------DAGSALCTSSIVIKEPKKPPVF---DQHLTPVTV 8357
Query: 662 SRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVF 721
S + +QG++ IQ L+ K R ++ A V
Sbjct: 8358 SEGEYVQLSCHVQGSEPIRIQWLKAGREIKP------SDRCSFS--------FASGTAVL 8403
Query: 722 NIQE-PEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFE 780
+++ + ++ + K S+ ++ + ++ P + D + FF
Sbjct: 8404 ELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRL------FFV 8457
Query: 781 MKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFK-DGKQISPKSDHYTIQRDLDGTCSLHTT 839
+ + ++ E TF +V G+P P + W K +Q++ + Q+ + + T
Sbjct: 8458 SEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDT 8517
Query: 840 ASTLDDDGNYTIMAANPQGRISCTGRLMV 868
T D G Y +A N G I L V
Sbjct: 8518 TKT--DSGLYRCVAFNEHGEIESNVNLQV 8544
Score = 89.0 bits (219), Expect = 2e-17
Identities = 44/95 (46%), Positives = 69/95 (72%), Gaps = 1/95 (1%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A P F+Q+L+S V +GS+V L+ RVTG PTP V+++ +G E+ ++ D QI E GDL++
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQE-GDLYS 160
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
L+IAEA+ +D+G Y+ ATN G T++AE+ ++G
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195
Score = 89.0 bits (219), Expect = 2e-17
Identities = 83/333 (24%), Positives = 130/333 (39%), Gaps = 52/333 (15%)
Query: 771 VENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDL 830
++ + P F KL G + C+V+G+ WFKDGK+IS + + +
Sbjct: 5231 LDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCH-- 5288
Query: 831 DGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRP 890
+ + SL L+D NYT +N G +C+G L V+
Sbjct: 5289 ERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK--------------------- 5327
Query: 891 RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
EP P FL PG + G P + W D
Sbjct: 5328 -----------EP-------PSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKD--D 5367
Query: 951 VRPDSAHKMLVRENGVHSLI-IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP 1009
V S K + G S + + V + G YTC TN G +S + L+V +P
Sbjct: 5368 VELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVT-----EP 5422
Query: 1010 PVFIEKLQNTGVAD-GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
P F++KL+ + + G RLEC++ G P ++ W + L S D+ I
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVI- 5481
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
+ + ED+G + A+N AG SC+ ++ V
Sbjct: 5482 -QMNNLSTEDSGDFICEAQNPAGSTSCSTKVIV 5513
Score = 88.6 bits (218), Expect = 3e-17
Identities = 63/227 (27%), Positives = 93/227 (40%), Gaps = 33/227 (14%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISP--KSDHYTIQRDLDGTC 834
P F + L + + G V F + +P+P + W+K G++I P YT + D G
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESD-KGLY 31748
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 894
L + T DDD YT++A N G SC +L V HP
Sbjct: 31749 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTL-------------HP--------- 31786
Query: 895 RDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
P + RP F + + QEG+ + +VSG+P P L W+ DG+P+
Sbjct: 31787 --------PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLG 31838
Query: 955 SAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+++ ++L I D G Y ATN AG S L V
Sbjct: 31839 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 31885
Score = 88.2 bits (217), Expect = 4e-17
Identities = 75/312 (24%), Positives = 129/312 (41%), Gaps = 45/312 (14%)
Query: 254 NRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHN 313
N+ H Q L P F++K +SQ+V +RV L+ V G ++WF + KELH+
Sbjct: 4751 NKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHS 4810
Query: 314 TPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSES 373
+ + +L + A D+G Y C +N G+ T+ A +F++ +
Sbjct: 4811 GAARSVWKDDTST-SLELFAAKATDSGTYICQLSNDVGTATSKATLFVK------EPPQF 4863
Query: 374 LAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVT--------TAV----------IQPLS 415
+ S + Q T +T +PK V+ TA+ +
Sbjct: 4864 IKKPSPVLVLRNGQSTTFECQIT---GTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQ 4920
Query: 416 VPVQQVHSPTSYLC--RPDGTTTAYF-------PPVFTKELQNTAVAEGQVVVLECRVRG 466
+ +V + +Y+C R D T + PP F +EL+ V + V LEC V G
Sbjct: 4921 ISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTG 4980
Query: 467 APPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARND 526
PP +V W + EI+ S + + + + L I + P D G + C N+
Sbjct: 4981 TPPFEVTWLKNNREIRSSKKYTLTDR--------VSVFNLHITKCDPSDTGEYQCIVSNE 5032
Query: 527 YGSATSTAQLVV 538
GS + + ++ +
Sbjct: 5033 GGSCSCSTRVAL 5044
Score = 87.8 bits (216), Expect = 5e-17
Identities = 91/327 (27%), Positives = 140/327 (42%), Gaps = 58/327 (17%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
F +K K+ E F C V+ P + W KD +++ +D IQ++ L
Sbjct: 3060 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQI-TDRIKIQKE-KYVHRLLI 3116
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
++ + D G YT++A G +S T +L V+ + R RS +
Sbjct: 3117 PSTRMSDAGKYTVVAG---GNVS-TAKLFVEGRDVRIRSIKK------------------ 3154
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV--RPDSA 956
E + I+++ +A + V E + D W DG + +
Sbjct: 3155 -EVQVIEKQ-------RAVVEFEVNEDDV-------------DAHWYKDGIEINFQVQER 3193
Query: 957 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
HK +V E +H + I DAG YT +A G+N S+ L V A E PP +++L
Sbjct: 3194 HKYVV-ERRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYVNAPE---PPQVLQEL 3245
Query: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 1076
Q V G P R + G P P+I W KE + L+ +H D Y LLI+ A
Sbjct: 3246 QPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLH-DGQEYTLLLIE-AFP 3303
Query: 1077 EDAGWYTVSAKNEAGIVSCTARLDVYI 1103
EDA YT AKN+ G+ + +A L V +
Sbjct: 3304 EDAAVYTCEAKNDYGVATTSASLSVEV 3330
Score = 87.4 bits (215), Expect = 7e-17
Identities = 70/300 (23%), Positives = 129/300 (43%), Gaps = 39/300 (13%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP FI + RSQ + EG V C ++G P+P + WF + + ++ I ++++L
Sbjct: 33133 APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSI-SRSRNVYSL 33191
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI---------EGASSTDSD-SESLAFKSR 379
I A D+G+YT A N G + +A + + E T D S +F S+
Sbjct: 33192 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQ 33251
Query: 380 AGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVP-------------------VQQ 420
+ M ++++ + S + S+S T + A + S+ + Q
Sbjct: 33252 SVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQ 33311
Query: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
+ S TS + + PP + ++ EG+V+ + C G P +V W G +
Sbjct: 33312 LESSTSKMLK---AGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRK 33368
Query: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
I R +++ TL+I + +D G++T S N++GS ++T + + S
Sbjct: 33369 IHSQEQGRF------HIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 33422
Score = 87.0 bits (214), Expect = 9e-17
Identities = 76/312 (24%), Positives = 120/312 (38%), Gaps = 48/312 (15%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P C V G P+ WFKDG+++S S H+ ++ SL + + D G Y+
Sbjct: 6659 GNPFALECVVTGTPELSAKWFKDGRELSADSKHHITF--INKVASLKIPCAEMSDKGLYS 6716
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
N G+ +CT + V +R
Sbjct: 6717 FEVKNSVGKSNCTVSVHVS------------------------------------DRIVP 6740
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F++ D+ G ++C+VSG + W DG + + EN V +L
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN-VCTLN 6799
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 1030
+ + D GIYTC+A N AG + S L V +PP F + + V G +
Sbjct: 6800 LSLLEPSDTGIYTCVAANVAGSDECSAVLTV-----QEPPSFEQTPDSVEVLPGMSLTFT 6854
Query: 1031 CRVLGVPPPQIFW-KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
+ G PP ++ W K E + + +S+ +Q ++G Y+ N+
Sbjct: 6855 SVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPL---ESGDYSCLVTND 6911
Query: 1090 AGIVSCTARLDV 1101
AG SCT L V
Sbjct: 6912 AGSASCTTHLFV 6923
Score = 83.6 bits (205), Expect = 1e-15
Identities = 65/204 (31%), Positives = 94/204 (46%), Gaps = 26/204 (12%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA-HKMLVRENGVHSL 969
PHF + +L V+ + CKV+G P P + W GK + D +++ + G H L
Sbjct: 30928 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 30987
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNS--FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
II VT DA +Y ATN+ G S SLE+ V AK H P +E + G V
Sbjct: 30988 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK-IHLPKT-LEGMGAVHALRGEVV 31045
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLI----------QGATKE 1077
++ G P P I W+K + + DN+G+ +++ G ++
Sbjct: 31046 SIKIPFSGKPDPVITWQKGQDLI-----------DNNGHYQVIVTRSFTSLVFPNGVERK 31094
Query: 1078 DAGWYTVSAKNEAGIVSCTARLDV 1101
DAG+Y V AKN GI T LDV
Sbjct: 31095 DAGFYVVCAKNRFGIDQKTVELDV 31118
Score = 82.4 bits (202), Expect = 2e-15
Identities = 187/867 (21%), Positives = 319/867 (36%), Gaps = 161/867 (18%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
P F +KL S + + ECR+T G+PT V W +GK L +++ E G +
Sbjct: 1703 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC-S 1761
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQK 388
L A+ D+G TC ATN G+D TSA + ++ D +SL +S+ +P+ +K
Sbjct: 1762 LDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK-------DEKSLVEESQ---LPEGRK 1811
Query: 389 KTTSVS--LTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKE 446
+ + TGVTT + +PD Y PV
Sbjct: 1812 GLQRIEELERMAHEGALTGVTTDQKEKQ---------------KPD--IVLYPEPV---- 1850
Query: 447 LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTL 506
V EG+ CRV G P +V W+ G I+ S FR+ + I L
Sbjct: 1851 ----RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV---------RYDGIHYL 1897
Query: 507 VIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPP 566
I + D G +A N G +L + E + P P
Sbjct: 1898 DIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI-----------QQREDFRSVLRRAPEPR 1946
Query: 567 PILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHP--SRGVNGLIN 624
P K E+Q+V+ P + + ++ AER T+ P S +
Sbjct: 1947 PEFHVHE---PGKLQFEVQKVDRP-VDTTETKEVVKLKRAERITHEKVPEESEELRSKFK 2002
Query: 625 GKANSNKSLPTPAVLLSPTKEP---PPLLAKPK---LGFPKKASRTARIASDEEIQGTKD 678
+ AV L K+ LL K K L + K+ + + A EE + T
Sbjct: 2003 RRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIP 2062
Query: 679 AVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQ-----EPEEETANQ 733
D K+ + P++ ER+ + +G S F ++ +PE E
Sbjct: 2063 TFKPD---KIELSPSM---EAPKIF--ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKN 2114
Query: 734 EYKVSSCE-------QRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHY 786
K+ + + + E+ R + + D + V+ ++ E F ++ K
Sbjct: 2115 GVKIERSDRIYWYWPEDNVCELVIR-DVTAEDSASIMVKAINIAGETSSHAFLLVQAKQL 2173
Query: 787 KIF-----------EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
F + TF C + P K+ W+KDG ++ + D Y + D
Sbjct: 2174 ITFTQELQDVVAKEKDTMATFECETS-EPFVKVKWYKDGMEVH-EGDKYRMHSDRKVHFL 2231
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
T T D + ++ + + T +L+V+
Sbjct: 2232 SILTIDTSDAEDYSCVLVEDE--NVKTTAKLIVEGA------------------------ 2265
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
F++ D+ V E ++C VS + W + ++ +
Sbjct: 2266 --------------VVEFVKELQDIEVPESYSGELECIVSP-ENIEGKWYHNDVELKSNG 2310
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK 1015
+ + R G +L ++ VT D G Y+ + + + K +P ++
Sbjct: 2311 KYTITSR-RGRQNLTVKDVTKEDQGEYSFVIDGK--------KTTCKLKMKPRPIAILQG 2361
Query: 1016 LQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGAT 1075
L + V +G V+LE +V + + W K+ + + S DRV + D ++ LLI+ T
Sbjct: 2362 LSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPS-DRVHIVIDKQSHM-LLIEDMT 2418
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDVY 1102
KEDAG Y+ + A +S + R+ VY
Sbjct: 2419 KEDAGNYSFTI--PALGLSTSGRVSVY 2443
Score = 81.6 bits (200), Expect = 4e-15
Identities = 71/279 (25%), Positives = 119/279 (42%), Gaps = 37/279 (13%)
Query: 264 ALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL--HNTPDIQIHC 321
A+ P F++KL++ + EGSR+ ++ R TGNP P + W + H P I+I
Sbjct: 1549 AVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1608
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
G+ L I D+ YT A N +G DTT +V +E + F
Sbjct: 1609 TKGEA-ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-----------VEF----- 1651
Query: 382 AMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP 441
A P+ ++K + + G+ K + ++PL + Q L + P
Sbjct: 1652 AEPEPERK---LIIPRGTYRAKE-IAAPELEPLHLRYGQEQWEEGDLYDKEKQQ----KP 1703
Query: 442 VFTKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
F K+L + + ECR+ G P + V+W G ++ + R++ +
Sbjct: 1704 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINE------- 1756
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
C+L + D+GI TC A N YG+ ++A L+V
Sbjct: 1757 -FGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1794
Score = 81.3 bits (199), Expect = 5e-15
Identities = 75/322 (23%), Positives = 123/322 (38%), Gaps = 50/322 (15%)
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
EG RVAG+ + W+K+ +I P S+ ++ T L + ++D G Y
Sbjct: 8263 EGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKN--NTLVLQVRKAGMNDAGLY 8320
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 909
T +N G CT +++ + P+ P P+ ++
Sbjct: 8321 TCKVSNDAGSALCTSSIVI-------KEPKKP---------------------PVFDQHL 8352
Query: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
P +TV EG+ ++ C V G + W G+ ++P +G L
Sbjct: 8353 TP--------VTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFA-SGTAVL 8403
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV----------FIEKLQNT 1019
+ V D+G Y C A+N AG ++ ++ + K A P F+ + Q+
Sbjct: 8404 ELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSI 8463
Query: 1020 GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 1079
V + +V G P P + W K + RV +HQ L I+ TK D+
Sbjct: 8464 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKG-DEAKLEIRDTTKTDS 8522
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G Y A NE G + L V
Sbjct: 8523 GLYRCVAFNEHGEIESNVNLQV 8544
Score = 79.0 bits (193), Expect = 2e-14
Identities = 63/240 (26%), Positives = 100/240 (41%), Gaps = 10/240 (4%)
Query: 772 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRD 829
E PFF+ KL ++ P F CR+ G+P + W DGK + + I
Sbjct: 1698 EKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEF 1757
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889
G CSL + D G T A N G + L+V+ + P G ++R
Sbjct: 1758 --GYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQR 1815
Query: 890 PRSRSRDSGDEN----EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQ 945
R + + Q+ +P + P + V EG+ R C+V+G P P ++W
Sbjct: 1816 IEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWY 1875
Query: 946 LDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
L+G+ +R + + VR +G+H L I S D G A N G ++L + +E
Sbjct: 1876 LNGQLIR--KSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1933
Score = 79.0 bits (193), Expect = 2e-14
Identities = 68/272 (25%), Positives = 110/272 (40%), Gaps = 50/272 (18%)
Query: 742 QRLISEIEYRLERSPVDESGDEVQYG----------DVPVENGMAPFFEMKLKHYKIFEG 791
+ LI +EY R + G E ++ DVP++ AP F+ +L++ +
Sbjct: 30887 KNLIEGLEYEF-RVKCENLGGESEWSEISEPITPKSDVPIQ---APHFKEELRNLNVRYQ 30942
Query: 792 MPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTI 851
T C+V G+PKP + W++ GK+I Y IQ G L + T DD Y +
Sbjct: 30943 SNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQV 31002
Query: 852 MAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRP 911
A N G +S T L V+ + + P
Sbjct: 31003 RATNQGGSVSGTASLEVE----------------------------------VPAKIHLP 31028
Query: 912 HFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLII 971
L+ G + G++ + SG P P ++WQ G+ + ++ H ++ SL+
Sbjct: 31029 KTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ-KGQDLIDNNGHYQVIVTRSFTSLVF 31087
Query: 972 -EPVTSRDAGIYTCIATNRAGQNSFSLELVVA 1002
V +DAG Y A NR G + ++EL VA
Sbjct: 31088 PNGVERKDAGFYVVCAKNRFGIDQKTVELDVA 31119
Score = 78.6 bits (192), Expect = 3e-14
Identities = 67/296 (22%), Positives = 121/296 (40%), Gaps = 45/296 (15%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP F + LR+ + L+C++ G+ RV WF +GKE+ + +I G +L
Sbjct: 4112 APFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTA-SL 4170
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKK 389
I +D G +TC ATN GS +S + ++ E +F ++ G+
Sbjct: 4171 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ---------EPPSFVTKPGSKDVLPGS 4221
Query: 390 TTSVSLTIGSSSPKT-----------------GVTTAVIQPLSVPVQQVHSPTSYLCRPD 432
+ T S+P T A+ L + + + +Y C+
Sbjct: 4222 AVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVS 4281
Query: 433 GTTTAY---------FPPVFTKELQ-NTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQ 482
P F ++L+ + + +G L C+V G PP+++ WF EI+
Sbjct: 4282 NVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIK 4341
Query: 483 DSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+S R+ + E L + + ED+G + C A+N+ GS ++ ++V
Sbjct: 4342 ESSKHRM--------SFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIV 4389
Score = 77.8 bits (190), Expect = 5e-14
Identities = 42/99 (42%), Positives = 63/99 (63%), Gaps = 8/99 (8%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP F + LQ+ V +G V L+ RV G P V+++R G+EIQ S DF+I Q+
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQE------- 155
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ +L+IAE +PED+G ++ +A N G ATSTA+L+V
Sbjct: 156 -GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 76.6 bits (187), Expect = 1e-13
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 12/195 (6%)
Query: 915 QAPG------DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS 968
+APG D+T + G+ ++ C++ G P PD+ W GK + +KM + H+
Sbjct: 30531 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS-SDGRTHT 30589
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
L + D G+YTCIATN G+ S +L++ A P +++ V G +R
Sbjct: 30590 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAV--GSTLR 30647
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L +G P P + W + L +++ +++ H ++ K AG Y V N
Sbjct: 30648 LHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSN 30706
Query: 1089 EAGIVSCTARLDVYI 1103
G V A LDV I
Sbjct: 30707 VFGTVD--AILDVEI 30719
Score = 75.1 bits (183), Expect = 3e-13
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 42/238 (17%)
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
P++ P + ++TV EG+ ++C +SG P+P ++W + + S +
Sbjct: 935 PVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIE-SSIDFQITF 993
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-------------- 1008
++G+ L+I + D+G +TC A N AG S S L V E +
Sbjct: 994 QSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEE 1053
Query: 1009 ---------------------------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQI 1041
P FI K + +G V C+V G P P +
Sbjct: 1054 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1113
Query: 1042 FWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
+WKK LT + G L+I +DAG YT+ +N+ G S +A L
Sbjct: 1114 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 74.3 bits (181), Expect = 6e-13
Identities = 78/323 (24%), Positives = 123/323 (38%), Gaps = 66/323 (20%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHN--TPDIQIHCEGGD 325
PAAP FI K Q++ EG V C+V GNP P V W G L + + + G+
Sbjct: 1079 PAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGE 1138
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ 385
L+I+ F DD G YT + N G + SA + E +D E L KS+ + Q
Sbjct: 1139 C-KLVISMTFADDAGEYTIVVRNKHGETSASASLLEE------ADYE-LLMKSQQEMLYQ 1190
Query: 386 AQKKTTSVSLTIGSSSP--------------------KTGVTTAVIQPL----------- 414
Q +G ++P K T V++
Sbjct: 1191 TQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSF 1250
Query: 415 ------SVPVQQVHSPTSYLCRPDG--------TTTAYFPPVFTKELQNTAVAEGQVVVL 460
+ + + + L DG + + F ++N + EG V
Sbjct: 1251 EERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTF 1310
Query: 461 ECRVRGAPPLQVQWFRQGSEIQDSPDFRI--LQKKPRSTAEPEEICTLVIAETFPEDAGI 518
C++ G P ++ W++ G I+ +++ LQ + +L I PED GI
Sbjct: 1311 HCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQ---------DGRASLRIPVVLPEDEGI 1361
Query: 519 FTCSARNDYGSATSTAQLVVTSA 541
+T A N G+A + +L V A
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPA 1384
Score = 74.3 bits (181), Expect = 6e-13
Identities = 74/308 (24%), Positives = 117/308 (37%), Gaps = 33/308 (10%)
Query: 253 HNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELH 312
HN +AL A P F QK +GS V L+C ++G P V W + K++
Sbjct: 6440 HNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVR 6499
Query: 313 NTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEV-------FIEGAS 365
N+ +I + D +L I D G Y C ATN GSDT S V F++ S
Sbjct: 6500 NSKKFKITSKHFDT-SLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLS 6558
Query: 366 STDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT 425
T S + A+ + + + V L + T + ++ Q+ SP
Sbjct: 6559 DT---STLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPE 6615
Query: 426 S-----YLCR---------PDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQ 471
+ Y+C+ T P ++ + V G LEC V G P L
Sbjct: 6616 ASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELS 6675
Query: 472 VQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSAT 531
+WF+ G E+ I ++ +L I D G+++ +N G +
Sbjct: 6676 AKWFKDGRELSADSKHHI--------TFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSN 6727
Query: 532 STAQLVVT 539
T + V+
Sbjct: 6728 CTVSVHVS 6735
Score = 73.9 bits (180), Expect = 8e-13
Identities = 60/269 (22%), Positives = 118/269 (43%), Gaps = 17/269 (6%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F ++++ + EG V C+++G P P++ W+ +GK + + Q+ +L I
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1352
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDS--ESLAFKSRAGAMPQAQKKT 390
+D G YT A+N G+ S ++++E A+ + + +L SR ++
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1412
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPD-GTTTAYFPPVFTKELQN 449
+ + ++ SP ++ A + P + SP L D + PVF + +
Sbjct: 1413 SPIRMSPARMSP-ARMSPARMSPARM------SPGRRLEETDESQLERLYKPVFVLKPVS 1465
Query: 450 TAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIA 509
EGQ + +V G P + WF G +I + +++ K+ + +L+I
Sbjct: 1466 FKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-------SLIIV 1518
Query: 510 ETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P D+G +T A+N G ++ + L V
Sbjct: 1519 PATPSDSGEWTVVAQNRAGRSSISVILTV 1547
Score = 72.4 bits (176), Expect = 2e-12
Identities = 70/296 (23%), Positives = 121/296 (40%), Gaps = 33/296 (11%)
Query: 264 ALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEG 323
AL P F+ K S++V GS V L+ G+ +RWF KEL + I E
Sbjct: 4199 ALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEA 4258
Query: 324 GDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAM 383
+ +L + D+G YTC +N +G SA +F++ ++ E + A
Sbjct: 4259 LE-SSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDAT 4317
Query: 384 PQAQKKTTSVSLTIG----------SSSPKTGV--TTAVIQPLSVPVQQVHSPTSYLCRP 431
A K T + + I SS + +TAV++ V ++ Y+C
Sbjct: 4318 QLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIED---SGEYMCEA 4374
Query: 432 DGTTTAYF---------PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQ 482
+ P FTKE + V + V+L V G PP ++ WF+ + ++
Sbjct: 4375 QNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILR 4434
Query: 483 DSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ T + + +L I + DAG + C N+ GS+ +A++ +
Sbjct: 4435 SGRKYK--------TFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTL 4482
Score = 69.7 bits (169), Expect = 1e-11
Identities = 78/297 (26%), Positives = 119/297 (40%), Gaps = 60/297 (20%)
Query: 804 PKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCT 863
P+ K+ W+K +++ P SD + I D D +L L D GNY ++
Sbjct: 8684 PEIKLSWYKGTEKLEP-SDKFEISIDGDRH-TLRVKNCQLKDQGNYRLVCG--------- 8732
Query: 864 GRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQ 923
PH+ + EP ER + D+T++
Sbjct: 8733 ---------------------PHIASAKLTVI------EPAWERHLQ--------DVTLK 8757
Query: 924 EGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYT 983
EG+ C M C+ S +P W +G+ ++P HK V E+ VH L I V + D G YT
Sbjct: 8758 EGQTCTMTCQFS-VPNVKSEWFRNGRILKPQGRHKTEV-EHKVHKLTIADVRAEDQGQYT 8815
Query: 984 CIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFW 1043
C + S EL + A +P F +++QN V++ EC V + W
Sbjct: 8816 C----KYEDLETSAELRIEA----EPIQFTKRIQNIVVSEHQSATFECEV-SFDDAIVTW 8866
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE-AGIVSCTARL 1099
K LT S + + D + + I T +D G Y+V A+ E G TA L
Sbjct: 8867 YKGPTELTES-QKYNFRNDGRCHY-MTIHNVTPDDEGVYSVIARLEPRGEARSTAEL 8921
Score = 69.7 bits (169), Expect = 1e-11
Identities = 147/793 (18%), Positives = 273/793 (34%), Gaps = 80/793 (10%)
Query: 215 LSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFI 274
+ AS+S ++ Q RE S + + A+ + A R +
Sbjct: 32505 MEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARIL 32564
Query: 275 QKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEA 334
K RS V EG C G P P V W +G+ L + Q+ T I+
Sbjct: 32565 TKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYK-STFEISSV 32623
Query: 335 FEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVS 394
D G Y+ + N G + I+ A T+ S P+ + V
Sbjct: 32624 QASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTS---------PPRVKSPEPRVK 32674
Query: 395 LTIGSSSPKTGVTTAVIQPLSV-PVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVA 453
SPK + P +V P + +PT + PP T+ L+ A A
Sbjct: 32675 SPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH----LPVSAPPKITQFLK--AEA 32728
Query: 454 EGQVVVLECRVRGA--PPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
++ L C V + +V W++ G +++++ F+ T E L I
Sbjct: 32729 SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQ-FHYSADGTYE------LKINNL 32781
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGES-NNDHFQHFPPPPPILE 570
D G + C + G++ + Q + + + + + E+ +D E
Sbjct: 32782 TESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTE 32841
Query: 571 TSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSN 630
+ E S KP + + + + A E + G GK +
Sbjct: 32842 PKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS 32901
Query: 631 KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRF 690
+ + + T L + K ++ + + I+ KD Q K+
Sbjct: 32902 EDKGGFFLEIHKTDTSDSGLYTCTV---KNSAGSVSSSCKLTIKAIKDTEAQ----KVST 32954
Query: 691 KEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEY 750
++ Q + +E ++++ L ++ + + E+ +E + +
Sbjct: 32955 QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAAT 33014
Query: 751 RLERSPVDESGDEVQYGDVPVENGMAPFFEMKL--KHYKIFEGMPVTFTCRVAGNPKPKI 808
LE+S V E + V E+K I EG + +AG K
Sbjct: 33015 SLEKSIVHEEITKTSQASEEVRT----HAEIKAFSTQMSINEGQRLVLKANIAGATDVK- 33069
Query: 809 YWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
W +G +++ ++ D T ++ + D+G T ++ +G + C L +
Sbjct: 33070 -WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHR--DEGILTCISKTKEGIVKCQYDLTL 33126
Query: 869 QAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLC 928
S + +PRS++ + EG+
Sbjct: 33127 --------SKELSDAPAFISQPRSQN---------------------------INEGQNV 33151
Query: 929 RMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATN 988
C++SG P+P++ W + P+ S++ + R V+SL I + D+G YT A N
Sbjct: 33152 LFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKN 33210
Query: 989 RAGQNSFSLELVV 1001
GQ S + L+V
Sbjct: 33211 FRGQCSATASLMV 33223
Score = 69.3 bits (168), Expect = 2e-11
Identities = 120/637 (18%), Positives = 230/637 (36%), Gaps = 71/637 (11%)
Query: 255 RKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT 314
RK+ P+ + + P + L+ V+ S + TG P P W +GK +
Sbjct: 32838 RKTEPKAPEPIS--SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG 32895
Query: 315 PDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL 374
++ + G L I + D+G YTC N +GS ++S ++ I+ T++ S
Sbjct: 32896 GKYKLSEDKGGFF-LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVST 32954
Query: 375 AFKSRAGAMPQA-------QK--KTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT 425
S +A QK ++ + ++ S K + + L + + T
Sbjct: 32955 QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAAT 33014
Query: 426 SY---LCRPDGTTTAYFPPVFTKELQNTA------VAEGQVVVLECRVRGAPPLQVQWFR 476
S + + T T+ + A + EGQ +VL+ + GA V+W
Sbjct: 33015 SLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT--DVKWVL 33072
Query: 477 QGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL 536
G E+ +S ++R + ++ TL I + D GI TC ++ G L
Sbjct: 33073 NGVELTNSEEYRY------GVSGSDQ--TLTIKQASHRDEGILTCISKTKEGIVKCQYDL 33124
Query: 537 VVTSANTENCSYESMGESNN-DHFQHFPPPPPILETSSLELA-SKKPSEIQQVNNPELGL 594
++ ++ ++ S S N + Q+ I S E+ K I +N +
Sbjct: 33125 TLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR 33184
Query: 595 SRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPK 654
SR ++ A +G + + N G+ ++ SL ++ P++E
Sbjct: 33185 SRNVYSLEIRNASVSDSGKYTIKAKN--FRGQCSATASLMVLPLVEEPSREV-------- 33234
Query: 655 LGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLG 714
R + D +QG+ + + K++ + + +
Sbjct: 33235 ---------VLRTSGDTSLQGSFSSQSVQMSAS---KQEASFSSFSSSSASSMTEMKFAS 33282
Query: 715 ADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENG 774
+ ++ ++QE E ++ + S +L S L+ G
Sbjct: 33283 MSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGI----------------RG 33326
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
+ P E I EG +T C G P P++ W G++I + + D
Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 33386
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAV 871
+L D G YT+ N G S T + ++++
Sbjct: 33387 TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 33423
Score = 65.5 bits (158), Expect = 3e-10
Identities = 38/105 (36%), Positives = 55/105 (52%), Gaps = 3/105 (2%)
Query: 258 HPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDI 317
HP P + P F + L + E EG V E RV+G P P ++W +G+ L P+I
Sbjct: 31785 HPPPTDST---LRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNI 31841
Query: 318 QIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+I EG D + L I + +DTG Y ATN +GS + A + +E
Sbjct: 31842 EIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 31886
Score = 64.7 bits (156), Expect = 5e-10
Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Query: 1009 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
PP + L+N V +G V LEC + G P P + W +E+ + S D Q G
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQS--GIAR 999
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 1104
L+I+ A ED+G +T SA NEAG VS + L V +S
Sbjct: 1000 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 1035
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/127 (31%), Positives = 66/127 (51%), Gaps = 4/127 (3%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT--PDIQIHCEGGDLH 327
AP F Q L+S V EGS E ++G P P V WF +G+ + + P +QI G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA- 63
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL-AFKSRAGAMPQA 386
L I + ++GRY+ ATN SG T++AE+ ++ ++ + + L + R G+ +
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 387 QKKTTSV 393
Q + T +
Sbjct: 124 QVRVTGI 130
Score = 62.4 bits (150), Expect = 2e-09
Identities = 55/226 (24%), Positives = 91/226 (40%), Gaps = 28/226 (12%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P F+ L + EG V +C V G+ +I W K G++I P SD + GT L
Sbjct: 8346 PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKP-SDRCSFSF-ASGTAVL 8403
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
D G+Y A+N G + ++ ++ P+ P ++
Sbjct: 8404 ELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKD---------KPAVAPATKKAA----- 8449
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956
+ R F F+ P + V E KV G P P++ W GK + +
Sbjct: 8450 -------VDGRLF---FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW-TKGKWRQLNQG 8498
Query: 957 HKMLVRENGVHS-LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
++ + + G + L I T D+G+Y C+A N G+ ++ L V
Sbjct: 8499 GRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQV 8544
Score = 62.4 bits (150), Expect = 2e-09
Identities = 198/944 (20%), Positives = 315/944 (33%), Gaps = 199/944 (21%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F L+ V E + EC +T V W +G ++ + D G H L+I
Sbjct: 11488 FAVPLKDVTVPERRQARFECVLTREAN--VIW-SKGPDIIKSSDKFDIIADGKKHILVIN 11544
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGA---------SSTDSDSESLAF------- 376
++ DD G YT TSA +F+ G T + E+ F
Sbjct: 11545 DSQFDDEGVYTAEVEGKK----TSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHE 11600
Query: 377 KSRAGAMPQAQKKTTSVSLTIGSSSP--KTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT 434
K K TS ++ I S K + + +S Q+ + L
Sbjct: 11601 KMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDIS----QIKAQVKELSSTAQL 11656
Query: 435 TTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKP 494
P FT +L + E + L+C V P V+WF+ G EI SP + I
Sbjct: 11657 KVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSPKYSIKADGL 11714
Query: 495 RSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT----------E 544
R L I + +D G + C D A T + + E
Sbjct: 11715 RR--------ILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGE 11766
Query: 545 NCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFN 604
+E + H Q P+ + E+ I ++N +LG++ ++ F
Sbjct: 11767 TAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTG---EVSFQ 11823
Query: 605 AAERETNGVHPSRGVNGLINGKANSN-KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASR 663
AA N K+ +N K P + ++P + + K + F + SR
Sbjct: 11824 AA-----------------NAKSAANLKVKELPLIFITPLSD-VKVFEKDEAKFECEVSR 11865
Query: 664 ----------TARIASDEEIQGTKD----------AVIQDLERKLRFKEDLLNNGQ---- 699
T I D+ + KD A +D + + ED +G+
Sbjct: 11866 EPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIE 11925
Query: 700 -PRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVD 758
RL + + + VF ++ + N K +QRL + ++
Sbjct: 11926 GIRLKFLTPLKDVTAKEKESAVFTVELSHD---NIRVKWFKNDQRLHTTRSVSMQDEGKT 11982
Query: 759 ESGDEVQYGDVPVEN---------GMA-----------PFFEMKLKHYKIFEGMPVTFTC 798
S + + D+ +++ GM+ P+F KL+ Y E V C
Sbjct: 11983 HS---ITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQC 12039
Query: 799 RVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDD-GNYTIMAANPQ 857
++ P + WFKDGK+I P + DG + L D G YT
Sbjct: 12040 EISKADAP-VKWFKDGKEIKPSKNAVI---KADGKKRMLILKKALKSDIGQYTCDC---- 12091
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP 917
G +G+L ++ + P R + S D+ + LQ P
Sbjct: 12092 GTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIH-ANWKLKGEALLQTP 12150
Query: 918 GDLTVQEGKL-------CRMD---------------------CKVSGLPTP--------- 940
+EGK+ CR+D +V GL P
Sbjct: 12151 DCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAG 12210
Query: 941 --------------DLSWQLDGKPVRPDSAHKMLVRENG-VHSLIIEPVTSRDAGIYTCI 985
+ W L GK + P + K++ R G VH+L + V DAG
Sbjct: 12211 ETATFDCELSYEDIPVEWYLKGKKLEP--SDKVVPRSEGKVHTLTLRDVKLEDAGEVQLT 12268
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPV-FIEKLQNTGVADGYPVRLECRVLGVPPPQIFWK 1044
A F + KE PPV F + L++ V +G LEC V ++ W
Sbjct: 12269 A------KDFKTHANLFVKE---PPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWF 12318
Query: 1045 KENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
K + S + + D L+I T ED YT AK+
Sbjct: 12319 KNGTEILKS-KKYEIVADGR-VRKLVIHDCTPEDIKTYTCDAKD 12360
Score = 61.6 bits (148), Expect = 4e-09
Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 7/143 (4%)
Query: 770 PVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD 829
P ++ + P F+ L + + EG V F RV+G P P + W KDG+ +S + I
Sbjct: 31788 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEG 31847
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHP-HVR 888
LD +LH + +D G Y + A N G SC L V+ + + + +S H HV+
Sbjct: 31848 LD-YYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQ 31906
Query: 889 RP-----RSRSRDSGDENEPIQE 906
+ R SG E+ P+ +
Sbjct: 31907 KQIDKTLRMAEILSGTESVPLTQ 31929
Score = 61.2 bits (147), Expect = 5e-09
Identities = 66/266 (24%), Positives = 105/266 (39%), Gaps = 25/266 (9%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+ ++ L S EV E E ++ + W +G+ L TPD +I E G +H+L++
Sbjct: 12108 KLVRPLHSVEVMETETARFETEISEDDI-HANWKLKGEALLQTPDCEIK-EEGKIHSLVL 12165
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG-----------ASSTDSDSESLAFKSRA 380
D TG A N S + + G A T + L+++
Sbjct: 12166 HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP 12225
Query: 381 GAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFP 440
KK + S K V T ++ + + T+ + P
Sbjct: 12226 VEWYLKGKKLEPSDKVVPRSEGK--VHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEP 12283
Query: 441 PV-FTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PV FTK L++ V EG VLEC V +V+WF+ G+EI S + I+
Sbjct: 12284 PVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIV--------A 12334
Query: 500 PEEICTLVIAETFPEDAGIFTCSARN 525
+ LVI + PED +TC A++
Sbjct: 12335 DGRVRKLVIHDCTPEDIKTYTCDAKD 12360
Score = 60.8 bits (146), Expect = 7e-09
Identities = 36/94 (38%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKE-LHNTPDIQIHCEGGDLHT 328
AP F ++LR+ V S L C+VTG+P P V+W+ +GKE + + +I G H
Sbjct: 30927 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 30986
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
LIIA +DD Y ATN GS + +A + +E
Sbjct: 30987 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 31020
Score = 58.9 bits (141), Expect = 3e-08
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP ++++ G L C++ G P P ++W+ GKEL + ++ + G HTL
Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSD-GRTHTL 30590
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+ ++D G YTC+ATN G TS+++ ++
Sbjct: 30591 TVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 30623
Score = 58.2 bits (139), Expect = 4e-08
Identities = 68/279 (24%), Positives = 108/279 (38%), Gaps = 25/279 (8%)
Query: 262 HSALHFPAAP-RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIH 320
H+ L P F + L Q V EG+ LEC V+ +V+WF G E+ + +I
Sbjct: 12275 HANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIV 12333
Query: 321 CEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSA----EVFIEGASSTDSDSESLAF 376
+ G + L+I + +D YTC A + S + F+ + + +A
Sbjct: 12334 AD-GRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMAR 12392
Query: 377 KSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC-----RP 431
+ A+ K I ++ ++ L + + Y C R
Sbjct: 12393 FECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTART 12452
Query: 432 DGTTTAY-FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
G T VFTK L N V+E + L C V P +V W++ EI ++ + IL
Sbjct: 12453 SGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEIL 12511
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTC---SARND 526
+ + LVI EDAG + C S+R D
Sbjct: 12512 TEGRKR--------ILVIQNAHLEDAGNYNCRLPSSRTD 12542
Score = 58.2 bits (139), Expect = 4e-08
Identities = 68/290 (23%), Positives = 101/290 (34%), Gaps = 73/290 (25%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F L ++ G V +T +P P V W+ G+++ + + +
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKY---------- 31739
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
FE D G Y L N + +TD D+E T
Sbjct: 31740 ---TFESDKGLYQ-LTIN---------------SVTTDDDAEY----------------T 31764
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT 450
G S K +T + P PT RP +F + L N
Sbjct: 31765 VVARNKYGEDSCKAKLTVTLHPP----------PTDSTLRP----------MFKRLLANA 31804
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
EGQ V E RV G PP ++W + G + P+ I+ E + L I +
Sbjct: 31805 ECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH-------EGLDYYALHIRD 31857
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQ 560
T PED G + +A N GS + A L V + ++S E + H Q
Sbjct: 31858 TLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSK-EEHERHVQ 31906
Score = 57.4 bits (137), Expect = 7e-08
Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 8/143 (5%)
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG----VAD 1023
S ++E + + A N G++ SL L V ++ PP +L G V
Sbjct: 15353 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKA 15412
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD----NHGYICLLIQGATKEDA 1079
G PV + V G+P P+I W K + TD + + ++ + L I A +ED
Sbjct: 15413 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 15472
Query: 1080 GWYTVSAKNEAGIVSCTARLDVY 1102
G YTV+A N G V ++VY
Sbjct: 15473 GTYTVTASNRLGSVFRNVHVEVY 15495
Score = 55.1 bits (131), Expect = 4e-07
Identities = 60/277 (21%), Positives = 110/277 (39%), Gaps = 45/277 (16%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F KL+ E V L+C ++ P V+WF +GKE+ + + I +G LI
Sbjct: 12018 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKK-RMLI 12075
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
+ +A + D G+YTC G+D TS ++ D + + ++ + +T
Sbjct: 12076 LKKALKSDIGQYTC----DCGTDKTSGKL--------DIEDREIKLVRPLHSVEVMETET 12123
Query: 391 TSVSLTIGSSSPKTG---VTTAVIQPLSVPVQQ---VHSPTSYLCRPDGTTTAYFPPVFT 444
I A++Q +++ +HS + CR D T F
Sbjct: 12124 ARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANV 12183
Query: 445 KE----------------LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
K L++ V G+ +C + + V+W+ +G +++ S
Sbjct: 12184 KSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPSD--- 12239
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARN 525
+ PRS ++ TL + + EDAG +A++
Sbjct: 12240 --KVVPRSEG---KVHTLTLRDVKLEDAGEVQLTAKD 12271
Score = 54.3 bits (129), Expect = 6e-07
Identities = 59/258 (22%), Positives = 105/258 (40%), Gaps = 44/258 (17%)
Query: 773 NGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG 832
+G AP ++K G +C++ G P P I W++ GK++ +S Y + D
Sbjct: 30529 SGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSD-GR 30586
Query: 833 TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 892
T +L +D+G YT +A N G + + +L++QA +P HP
Sbjct: 30587 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA---------TPQFHP------- 30630
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
P++E+++ G R+ G P P ++W G+ +
Sbjct: 30631 --------GYPLKEKYYG------------AVGSTLRLHVMYIGRPVPAMTW-FHGQKLL 30669
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSR-DAGIYTCIATNRAGQNSFSLELVVAAKEAHKP-- 1009
+S + + L+++ V + AG Y +N G L++ + K KP
Sbjct: 30670 QNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDK-PDKPTG 30728
Query: 1010 PVFIEK-LQNTGVADGYP 1026
P+ IE L+N+ V P
Sbjct: 30729 PIVIEALLKNSAVISWKP 30746
Score = 53.5 bits (127), Expect = 1e-06
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 1/97 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
LTV+ G +D V G P P +SW+ DG ++P KM ++ N + +L + V +D+
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 19363
Query: 980 GIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
G YT A N +G S +++L V K V I K+
Sbjct: 19364 GDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKM 19400
Score = 52.8 bits (125), Expect = 2e-06
Identities = 77/305 (25%), Positives = 118/305 (38%), Gaps = 60/305 (19%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
F L+ + EG C V+ K+ WFK+G +I KS Y I D L
Sbjct: 12287 FTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEIL-KSKKYEIVAD-GRVRKLVI 12343
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
T +D YT A + + SC ++ PHV
Sbjct: 12344 HDCTPEDIKTYTCDAKD--FKTSCNLNVVP----------------PHVE---------- 12375
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHK 958
FL+ DL V+E ++ R +C++S + W DG ++ +
Sbjct: 12376 --------------FLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAEIKKGKKYD 12420
Query: 959 MLVRENGVHSLIIEPVTSRDAGIYTC-IATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQ 1017
++ + V L+I D Y+C + T R S L V +EA VF + L
Sbjct: 12421 -IISKGAVRILVINKCLLDDEAEYSCEVRTART-----SGMLTVLEEEA----VFTKNLA 12470
Query: 1018 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKE 1077
N V++ ++L C V P ++ W K +E + T R + + I L+IQ A E
Sbjct: 12471 NIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEII-ETGRYEILTEGRKRI-LVIQNAHLE 12527
Query: 1078 DAGWY 1082
DAG Y
Sbjct: 12528 DAGNY 12532
Score = 52.8 bits (125), Expect = 2e-06
Identities = 31/94 (32%), Positives = 47/94 (50%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
P F E+L+N V L C+V G P P + W ++ + + + + + GY L
Sbjct: 30928 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 30987
Query: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
+I T +DA Y V A N+ G VS TA L+V +
Sbjct: 30988 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEV 31021
Score = 52.4 bits (124), Expect = 2e-06
Identities = 34/100 (34%), Positives = 46/100 (46%), Gaps = 10/100 (10%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDS--PDFRILQKKPRSTA 498
P FT+ LQ+ V EG E + G P +V WFR G I S P +I R+
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA-- 63
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L I ++G ++ A N G ATSTA+L+V
Sbjct: 64 ------KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 51.6 bits (122), Expect = 4e-06
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 25/271 (9%)
Query: 277 LRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE 336
+++ EV E EC V+ P + W G E+ + +I +G LH LII
Sbjct: 2888 MKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG-KLHQLIIMNTST 2945
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE---SLAFK---SRAGAMPQAQKKT 390
+D+ YT + N S T + + + D ++E ++ F+ + G + K
Sbjct: 2946 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 3005
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP---VFTKEL 447
+ T +T T + +V T + T T Y F K +
Sbjct: 3006 VEIKST-DKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHI 3064
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
++ V E + + EC V P + VQW + E+Q + +I ++K + L+
Sbjct: 3065 KDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEK--------YVHRLL 3115
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
I T DAG +T A G STA+L V
Sbjct: 3116 IPSTRMSDAGKYTVVA----GGNVSTAKLFV 3142
Score = 50.8 bits (120), Expect = 7e-06
Identities = 51/270 (18%), Positives = 102/270 (37%), Gaps = 28/270 (10%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP+ ++++SQ V +GS + RV G P P W+ G ++ + I + ++ L
Sbjct: 2077 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCEL 2136
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG----------ASSTDSDSESLAFKSR 379
+I + +D+ A N +G ++ A + ++ + +++A
Sbjct: 2137 VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFEC 2196
Query: 380 AGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC----RPDGTT 435
+ P + K + + + + LS+ Y C + T
Sbjct: 2197 ETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKT 2256
Query: 436 TAYF-----PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
TA F KELQ+ V E LEC V ++ +W+ E++ + + I
Sbjct: 2257 TAKLIVEGAVVEFVKELQDIEVPESYSGELECIV-SPENIEGKWYHNDVELKSNGKYTIT 2315
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFT 520
++ R L + + ED G ++
Sbjct: 2316 SRRGRQ--------NLTVKDVTKEDQGEYS 2337
Score = 50.8 bits (120), Expect = 7e-06
Identities = 35/127 (27%), Positives = 63/127 (49%), Gaps = 3/127 (2%)
Query: 905 QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 964
+E+ P L P +T++ GK R++ V G P P W+ G+ S+H + + +
Sbjct: 18894 KEQLLPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWK-KGEDEVVTSSHLAVHKAD 18951
Query: 965 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA-AKEAHKPPVFIEKLQNTGVAD 1023
LII+ VT +D+G Y+ A N +G ++ +++VV A +PP I + +
Sbjct: 18952 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL 19011
Query: 1024 GYPVRLE 1030
+ + LE
Sbjct: 19012 SWHIPLE 19018
Score = 50.8 bits (120), Expect = 7e-06
Identities = 57/257 (22%), Positives = 97/257 (37%), Gaps = 55/257 (21%)
Query: 284 EGSRVYLECRVTG-NPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRY 342
EG V C++ + + +V W+ ++L N+ +I E G + L + + + D G Y
Sbjct: 31581 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDG-VAILYVKDITKLDDGTY 31639
Query: 343 TCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSP 402
C N G D++ AE+F++G E + R M + +++T ++ L
Sbjct: 31640 RCKVVNDYGEDSSYAELFVKGV------REVYDYYCRR-TMKKIKRRTDTMRL------- 31685
Query: 403 KTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLEC 462
L RP P FT L N G+ V
Sbjct: 31686 -------------------------LERP---------PEFTLPLYNKTAYVGENVRFGV 31711
Query: 463 RVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCS 522
+ P V W++ G +I+ + K + + + L I +D +T
Sbjct: 31712 TITVHPEPHVTWYKSGQKIKPGDN-----DKKYTFESDKGLYQLTINSVTTDDDAEYTVV 31766
Query: 523 ARNDYGSATSTAQLVVT 539
ARN YG + A+L VT
Sbjct: 31767 ARNKYGEDSCKAKLTVT 31783
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/95 (35%), Positives = 56/95 (58%), Gaps = 5/95 (5%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKK-ENESLTHSTDR 1056
E V AKE PP + Q T + G +R+E V G P P WKK E+E +T S
Sbjct: 18888 EGVYEAKEQLLPPKILMPEQIT-IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSS--H 18944
Query: 1057 VSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
+++H+ + I L+I+ T++D+G+Y+++A+N +G
Sbjct: 18945 LAVHKADSSSI-LIIKDVTRKDSGYYSLTAENSSG 18978
Score = 50.1 bits (118), Expect = 1e-05
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHS-TDRVSMHQDNHGYIC 1068
PVF+ K + +G R + +V+G P P+ FW + + + + T +V + +D G
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED--GTQS 1514
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISRH 1106
L+I AT D+G +TV A+N AG S + L V H
Sbjct: 1515 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH 1552
Score = 49.7 bits (117), Expect = 2e-05
Identities = 41/158 (25%), Positives = 67/158 (42%), Gaps = 5/158 (3%)
Query: 205 LSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSA 264
L P ++ +L S S+SP+ M SP AR + R+ S
Sbjct: 1396 LEPVSRIRSLSPRSVSRSPIR----MSPARMSP-ARMSPARMSPARMSPGRRLEETDESQ 1450
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
L P F+ K S + EG + +V G P P WF +G+++ N ++ +
Sbjct: 1451 LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED 1510
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+LII A D+G +T +A N +G + S + +E
Sbjct: 1511 GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1548
Score = 49.7 bits (117), Expect = 2e-05
Identities = 73/280 (26%), Positives = 110/280 (39%), Gaps = 29/280 (10%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F + L + EV+E + L C V+ P V W+ +E+ T +I EG L+I
Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRK-RILVIQ 12522
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFI-EGASSTDSDSESLAFKS--RAGAMPQAQKK 389
A +D G Y C S T +V + E A+ S ++L +A + K+
Sbjct: 12523 NAHLEDAGNYNCRLP----SSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKE 12578
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT-----SYLCRPDGTTTAYFPPVFT 444
+ V + ++G VI V V T +Y+ A V
Sbjct: 12579 SFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIE 12638
Query: 445 K-----ELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
K L++T V E Q VV C V + +WFR I DS + ILQK
Sbjct: 12639 KLRIVVPLKDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQK------- 12690
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYG-SATSTAQLVV 538
+ + TL I + +D + S N G + S A L+V
Sbjct: 12691 -DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 12729
Score = 49.3 bits (116), Expect = 2e-05
Identities = 41/167 (24%), Positives = 69/167 (41%), Gaps = 22/167 (13%)
Query: 195 GESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDL----- 249
G + S DSG ++ + +++ ++D+ + E + P R Q ++L
Sbjct: 1765 GVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH 1824
Query: 250 -----AVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRW 304
V ++K +P L +P R V EG CRVTG P P+V W
Sbjct: 1825 EGALTGVTTDQKEKQKPDIVL-YPEPVR---------VLEGETARFRCRVTGYPQPKVNW 1874
Query: 305 FCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSG 351
+ G+ + + ++ +G +H L I + DTG A NP G
Sbjct: 1875 YLNGQLIRKSKRFRVRYDG--IHYLDIVDCKSYDTGEVKVTAENPEG 1919
Score = 49.3 bits (116), Expect = 2e-05
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 8/98 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P KE+++ G+ L C++ G P ++W+R G E ++Q + +
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKE--------LIQSRKYKMSSD 30584
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
TL + ED G++TC A N+ G ++++L++
Sbjct: 30585 GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLL 30622
Score = 49.3 bits (116), Expect = 2e-05
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 8/99 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE-IQDSPDFRILQKKPRSTAE 499
P F +EL+N V L C+V G P V+W+RQG E I D +RI + K
Sbjct: 30928 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFK------ 30981
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L+IA +DA ++ A N GS + TA L V
Sbjct: 30982 -GGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 31019
Score = 48.1 bits (113), Expect = 4e-05
Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 5/145 (3%)
Query: 960 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFS-LELVVAAKEAHKPPVFIEKLQN 1018
+V E+ V + ++ ++S + A N G++ L + V AK+ P
Sbjct: 24261 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 24320
Query: 1019 TGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKED 1078
+ G +++E V+G P P I W K+ E L +T RV++ + + L I+ K+D
Sbjct: 24321 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT-RVNVEETATSTV-LHIKEGNKDD 24378
Query: 1079 AGWYTVSAKNEAGIVSCTARLDVYI 1103
G YTV+A N AG + T L V +
Sbjct: 24379 FGKYTVTATNSAG--TATENLSVIV 24401
Score = 47.8 bits (112), Expect = 6e-05
Identities = 64/261 (24%), Positives = 98/261 (37%), Gaps = 49/261 (18%)
Query: 619 VNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKD 678
+ GL+ G+ + + P E P+LA LG P R + TK
Sbjct: 15256 ITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYT------ERTKS 15309
Query: 679 AVIQDLERKLRFKEDLLNNGQPRLTYE-----------ERMARRLLGADSATVFNIQEPE 727
+ D +KE N G P Y ER+ +RL S V N+ E +
Sbjct: 15310 TITLD------WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQ 15363
Query: 728 EETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLK--- 784
E++V + + I E E L + V +Q +VP P +++L
Sbjct: 15364 M----YEFRVKAVNE--IGESEPSLPLNVV------IQDDEVP------PTIKLRLSVRG 15405
Query: 785 -HYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD----LDGTCSLHTT 839
K+ G PV V G P PKI W K+ I +D I ++ + L
Sbjct: 15406 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 15465
Query: 840 ASTLDDDGNYTIMAANPQGRI 860
+ +D G YT+ A+N G +
Sbjct: 15466 KAVREDKGTYTVTASNRLGSV 15486
Score = 47.8 bits (112), Expect = 6e-05
Identities = 40/145 (27%), Positives = 70/145 (48%), Gaps = 21/145 (14%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V+A N++G+S G P + + + +P + F + +QA DL
Sbjct: 24285 VKAYNEKGKSDPRVLGVPVIAKDLTI--------QPSLKLPFNTYSIQAGEDL------- 24329
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI-IEPVTSRDAGIYTCIA 986
+++ V G P P++SW DG+P++ + ++ V E +++ I+ D G YT A
Sbjct: 24330 -KIEIPVIGRPRPNISWVKDGEPLKQTT--RVNVEETATSTVLHIKEGNKDDFGKYTVTA 24386
Query: 987 TNRAGQNSFSLELVVAAKEAHKPPV 1011
TN AG + +L ++V K PPV
Sbjct: 24387 TNSAGTATENLSVIVLEKPG--PPV 24409
Score = 47.4 bits (111), Expect = 8e-05
Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 5/110 (4%)
Query: 256 KSHPQ----PHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL 311
KS P+ P A P + + G + +E V G P P + W +G+ L
Sbjct: 24293 KSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL 24352
Query: 312 HNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
T + + E L I E +DD G+YT ATN +G+ T + V +
Sbjct: 24353 KQTTRVNVE-ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401
Score = 46.6 bits (109), Expect = 1e-04
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDD 338
S V G + +E ++G P P + W +G L T I + + DL TL I E +DD
Sbjct: 23238 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV-TDSLDLTTLSIKETHKDD 23296
Query: 339 TGRYTCLATNPSGSDTTSAEV 359
G+Y N G T S E+
Sbjct: 23297 GGQYGITVANVVGQKTASIEI 23317
Score = 46.2 bits (108), Expect = 2e-04
Identities = 48/182 (26%), Positives = 77/182 (42%), Gaps = 19/182 (10%)
Query: 925 GKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTC 984
G +C VS T +W DG +R H+ + + L I V DAG YTC
Sbjct: 11133 GSSAIFECLVSP-STAITTWMKDGSNIRESPKHRFIA-DGKDRKLHIIDVQLSDAGEYTC 11190
Query: 985 IATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQN-TGVADGYPVRLECRVLGVPPPQIFW 1043
+ + + + +LVV P F++ L+ V G P+ L C + + W
Sbjct: 11191 VLRLGNKEKTSTAKLVVE----ELPVRFVKTLEEEVTVVKGQPLYLSCELN--KERDVVW 11244
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLL----IQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
+K+ + + R+ G I L+ I A DAG YTV+ +N A + C++ +
Sbjct: 11245 RKDGKIVVEKPGRIVP-----GVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSSCV 11298
Query: 1100 DV 1101
V
Sbjct: 11299 KV 11300
Score = 46.2 bits (108), Expect = 2e-04
Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query: 997 LELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDR 1056
L + V AK+ PP F V G ++++ +G P P + W K+N L +T R
Sbjct: 22135 LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTT-R 22193
Query: 1057 VSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
V+ + + L I+ A +ED G Y V N AG
Sbjct: 22194 VNAESTENNSL-LTIKDACREDVGHYVVKLTNSAG 22227
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 12/138 (8%)
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRP-DSAHKMLVRENGVHSLIIE 972
LQ D V EG + +++ KVS L + + W DG+ V+P D H ++ +++ H L+IE
Sbjct: 2359 LQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQS--HMLLIE 2415
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
+T DAG Y+ +L L + + + I L++ V +G LEC+
Sbjct: 2416 DMTKEDAGNYSFTIP--------ALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECK 2467
Query: 1033 VLGVPPPQIFWKKENESL 1050
V + W +E +
Sbjct: 2468 VSVPDVTSVKWYLNDEQI 2485
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTGRYT 343
G LE V+G P P + W +GKEL T ++I D T L+ ++ D+G YT
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI--ADFSTNLVNKDSTRRDSGAYT 21533
Query: 344 CLATNPSG 351
ATNP G
Sbjct: 21534 LTATNPGG 21541
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G +RL V G PPP I W K+ L ++ Y L++ + DAG YT
Sbjct: 29461 GASLRLMVSVSGRPPPVITWSKQGIDLASR----AIIDTTESYSLLIVDKVNRYDAGKYT 29516
Query: 1084 VSAKNEAGIVSCTARLDVY 1102
+ A+N++G S T + VY
Sbjct: 29517 IEAENQSGKKSATVLVKVY 29535
Score = 45.4 bits (106), Expect = 3e-04
Identities = 84/380 (22%), Positives = 138/380 (36%), Gaps = 77/380 (20%)
Query: 760 SGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISP 819
+G+ + G + V G L + E F C VA NP K W +DGK +
Sbjct: 2606 AGENMTSGKLTVAGGA---ISKPLTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPL 2661
Query: 820 KSDHYTIQRDLDG-TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
++ I+ + DG L A+ LDD G YT A + + +L V+AV +
Sbjct: 2662 TNN---IRSESDGHKRRLIIAATKLDDIGEYTYKVATSK----TSAKLKVEAVKIKKTLK 2714
Query: 879 R------------SPSGHPHVRRPR------------------------SRSRDSGDENE 902
HP+V+ + R ++ +E
Sbjct: 2715 NLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDE 2774
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL----DGKPV------- 951
+ FR L A L V+ K+ + V+ L +++++ D PV
Sbjct: 2775 SVYG--FRLGRLGASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSV 2832
Query: 952 --RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP 1009
+P H+ LV E VH L+++ ++ DAG YT + GQ +L V K
Sbjct: 2833 EIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVETLHITK- 2886
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
++N V + EC V P ++ K E ++ + H L
Sbjct: 2887 -----TMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQ---L 2938
Query: 1070 LIQGATKEDAGWYTVSAKNE 1089
+I + ED+ YT N+
Sbjct: 2939 IIMNTSTEDSAEYTFVCGND 2958
Score = 44.7 bits (104), Expect = 5e-04
Identities = 80/363 (22%), Positives = 132/363 (36%), Gaps = 54/363 (14%)
Query: 263 SALHFPAAPRFIQKLRSQE---VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
S+ H PR I LR + V G +C ++ P V W+ +GK+L + +
Sbjct: 12185 SSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVP 12243
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI-EGASSTDSDSESLAFKS 378
EG +HTL + + +D G A + T A +F+ E E +
Sbjct: 12244 RSEG-KVHTLTLRDVKLEDAGEVQLTAKDFK----THANLFVKEPPVEFTKPLEDQTVEE 12298
Query: 379 RAGAMPQAQKKTTSVSLT-------IGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRP 431
A A+ + + + + I S V ++ L + +Y C
Sbjct: 12299 GATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 12358
Query: 432 DGTTTA----YFPP--VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSP 485
T+ PP F + L + V E ++ EC + +V+WF+ G+EI+
Sbjct: 12359 KDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGK 12417
Query: 486 DFRILQK---------KPRSTAEPEEICTLVIAE-----TFPEDAGIFTCSARNDYGSAT 531
+ I+ K K E E C + A T E+ +FT + N S T
Sbjct: 12418 KYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANIEVSET 12477
Query: 532 STAQLV--VTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNN 589
T +LV V+ E Y+ E I+ET E+ ++ I + N
Sbjct: 12478 DTIKLVCEVSKPGAEVIWYKGDEE--------------IIETGRYEILTEGRKRILVIQN 12523
Query: 590 PEL 592
L
Sbjct: 12524 AHL 12526
Score = 44.7 bits (104), Expect = 5e-04
Identities = 53/200 (26%), Positives = 88/200 (44%), Gaps = 32/200 (16%)
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH 886
++D D +HT A+ + + +T+ P ++ V AVN +G S S
Sbjct: 29382 EKDTDQWYRVHTNATIRNTE--FTV----PDLKMGQKYSFRVAAVNVKGMSEYS------ 29429
Query: 887 VRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL----TVQEGKLCRMDCKVSGLPTPDL 942
+S E EP+ ER P L+ DL T++ G R+ VSG P P +
Sbjct: 29430 ---------ESIAEIEPV-ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVI 29478
Query: 943 SWQLDGKPVRPDSAHKMLVRENGVHSL-IIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+W G D A + ++ +SL I++ V DAG YT A N++G+ S ++ + V
Sbjct: 29479 TWSKQGI----DLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 29534
Query: 1002 AAKEAHKPPVFIEKLQNTGV 1021
P V ++++ V
Sbjct: 29535 YDTPGPCPSVKVKEVSRDSV 29554
Score = 44.3 bits (103), Expect = 6e-04
Identities = 36/106 (33%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNT--GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTD 1055
E V+A H P V ++ V G +R+ RV G P P I W KE + L
Sbjct: 17895 ESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE-K 17953
Query: 1056 RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
RV + QD + L I+ A + D G Y +SAKN +G +A ++V
Sbjct: 17954 RVDLIQD-LPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNV 17998
Score = 44.3 bits (103), Expect = 6e-04
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G + ++ V G P PRV WF +G E+ +++I G +L + +A D G
Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST-SLFVRDATRDHRGV 28028
Query: 342 YTCLATNPSGSDTTSAEVFIE 362
YT A N SGS +V ++
Sbjct: 28029 YTVEAKNASGSAKAEIKVKVQ 28049
Score = 43.9 bits (102), Expect = 8e-04
Identities = 62/296 (20%), Positives = 111/296 (37%), Gaps = 58/296 (19%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGN-PTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
I+ + +Q V + + E + N P ++ W+ ++L + +I +G D HTL +
Sbjct: 8659 IKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDG-DRHTLRVK 8717
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFI---------------EGASSTDSDSESLA-- 375
D G Y + G SA++ + EG + T + S+
Sbjct: 8718 NCQLKDQGNYRLVC----GPHIASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNV 8773
Query: 376 ----FKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRP 431
F++ PQ + KT + L++ + Y C+
Sbjct: 8774 KSEWFRNGRILKPQGRHKTE---------------VEHKVHKLTIADVRAEDQGQYTCKY 8818
Query: 432 DGTTTAYF------PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSP 485
+ T+ P FTK +QN V+E Q EC V + V W++ +E+ +S
Sbjct: 8819 EDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAI-VTWYKGPTELTESQ 8877
Query: 486 DFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSAR-NDYGSATSTAQLVVTS 540
+ + I P+D G+++ AR G A STA+L +T+
Sbjct: 8878 KYNF--------RNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTT 8925
Score = 43.9 bits (102), Expect = 8e-04
Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG--VADGYPVRLECRVLGVPPPQIFW 1043
A N G+ + S VVA + P + ++ L + + RL+ + G P P + W
Sbjct: 19957 AENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 20016
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
KK + L T RVS+ + + L++ K DAG YT++ KN AG T + V
Sbjct: 20017 KKGEDPLATDT-RVSV-ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 20072
Score = 43.9 bits (102), Expect = 8e-04
Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 8/136 (5%)
Query: 744 LISEIEYRLERSPVDESG-DEVQYGDVPV---ENGMAPFFEMKLKHYKIFEGMPVTFTCR 799
L S EY+ +E G + + VPV + + P ++ Y I G +
Sbjct: 24275 LSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIP 24334
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGR 859
V G P+P I W KDG+ + ++ ++ T LH DD G YT+ A N G
Sbjct: 24335 VIGRPRPNISWVKDGEPLK-QTTRVNVEETATSTV-LHIKEGNKDDFGKYTVTATNSAG- 24391
Query: 860 ISCTGRLMVQAVNQRG 875
+ T L V + + G
Sbjct: 24392 -TATENLSVIVLEKPG 24406
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
L V+ G R + G+P P W DG ++ D H + +N L I+ RD
Sbjct: 17520 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDT 17578
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y +N AG + ++ L V
Sbjct: 17579 GEYQITVSNAAGSKTVAVHLTV 17600
Score = 43.5 bits (101), Expect = 0.001
Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSD-HYTIQRDLDGTCSLHTTASTLDDDGNY 849
G V V G P P + W KDG + P +QR+L C+L + D G+Y
Sbjct: 19310 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL---CTLELFSVNRKDSGDY 19366
Query: 850 TIMAANPQGRISCTGRLMV 868
TI A N G S T +L V
Sbjct: 19367 TITAENSSGSKSATIKLKV 19385
Score = 43.5 bits (101), Expect = 0.001
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
++ G+ R++ VSG P P + W DGK + + ++ + + +L+ + T RD+G
Sbjct: 21473 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 21531
Query: 982 YTCIATNRAG 991
YT ATN G
Sbjct: 21532 YTLTATNPGG 21541
Score = 43.1 bits (100), Expect = 0.001
Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 18/145 (12%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V AVN++GRS P V + + P A +VQ G+
Sbjct: 23203 VVAVNEKGRSDPRSLAVPIVAK----------------DLVIEPDVKPAFSSYSVQVGQD 23246
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIAT 987
+++ +SG P P ++W DG P++ + + + +L I+ D G Y
Sbjct: 23247 LKIEVPISGRPKPTITWTKDGLPLK-QTTRINVTDSLDLTTLSIKETHKDDGGQYGITVA 23305
Query: 988 NRAGQNSFSLELVVAAK-EAHKPPV 1011
N GQ + S+E+V K + K PV
Sbjct: 23306 NVVGQKTASIEIVTLDKPDPPKGPV 23330
Score = 42.7 bits (99), Expect = 0.002
Identities = 59/256 (23%), Positives = 100/256 (39%), Gaps = 28/256 (10%)
Query: 277 LRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE 336
L Q VAE EC V NP + W +GK L T +I+ + G LIIA
Sbjct: 2626 LTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPLTNNIRSESD-GHKRRLIIAATKL 2683
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGA-------SSTDSDSESLAFKSRAGAMPQAQKK 389
DD G YT + TSA++ +E + T ++++ F P +
Sbjct: 2684 DDIGEYTYKV----ATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL-THPNVKGV 2738
Query: 390 TTSVSLTIGSSSPKTGVTT-AVIQPLSVPVQQVHSPTSY---LCRPDGTTTAYFPPV-FT 444
+ + S+ K ++ I L + + + Y L R + + V
Sbjct: 2739 QWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKII 2798
Query: 445 KELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
K+ ++ E V E V + V+WF + EI+ S R++ ++ ++
Sbjct: 2799 KKPKDVTALENATVAFEVSV-SHDTVPVKWFHKSVEIKPSDKHRLVSER--------KVH 2849
Query: 505 TLVIAETFPEDAGIFT 520
L++ P DAG +T
Sbjct: 2850 KLMLQNISPSDAGEYT 2865
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG---VADGYPVRLECRVLGVPPPQIF 1042
A N AG+ V E +PP + G + G +R+ V G P P
Sbjct: 15078 AVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 15137
Query: 1043 WKKENESLTHSTDRVSMHQDNHGYIC-LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
W KE L DRV + DN G L+I+ A ++D G Y ++A N G AR++V
Sbjct: 15138 WTKEEGEL--DKDRVVI--DNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 15193
Query: 1102 Y 1102
+
Sbjct: 15194 F 15194
Score = 42.7 bits (99), Expect = 0.002
Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELV--VAAKEAHKPPVFIEKLQNTGVAD---G 1024
II +T + A N G S E+V + +++ PV L+ T V G
Sbjct: 26828 IISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAG 26887
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
V+L + G P P I W K+++ L T+ + ++ +LI+ A + ++G Y +
Sbjct: 26888 TSVKLRAGISGKPAPTIEWYKDDKEL--QTNALVCVENTTDLASILIKDADRLNSGCYEL 26945
Query: 1085 SAKNEAGIVSCTARLDV 1101
+N G S T R+ +
Sbjct: 26946 KLRNAMGSASATIRVQI 26962
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
I G + V G P P++ WFKDG +I + + D+ G+ SL +T D G
Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI--TDVLGSTSLFVRDATRDHRG 28027
Query: 848 NYTIMAANPQGRISCTGRLMVQ 869
YT+ A N G ++ VQ
Sbjct: 28028 VYTVEAKNASGSAKAEIKVKVQ 28049
Score = 42.4 bits (98), Expect = 0.002
Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 11/105 (10%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G ++ +E V G P P +W E+ + + +H + LII + D+G
Sbjct: 18910 IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVH-KADSSSILIIKDVTRKDSGY 18968
Query: 342 YTCLATNPSGSDTTSAEVFIEGA----------SSTDSDSESLAF 376
Y+ A N SG+DT +V + A S D+D+ SL++
Sbjct: 18969 YSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSW 19013
Score = 42.0 bits (97), Expect = 0.003
Identities = 41/146 (28%), Positives = 60/146 (41%), Gaps = 19/146 (13%)
Query: 402 PKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAY----FPPVFTKELQNTAVAEGQV 457
P GV P+ +++ + PD Y P F KE+++ + E +
Sbjct: 11072 PIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEF 11131
Query: 458 V----VLECRVRGAPPLQVQWFRQGSEIQDSPDFR-ILQKKPRSTAEPEEICTLVIAETF 512
V + EC V + + W + GS I++SP R I K R L I +
Sbjct: 11132 VGSSAIFECLVSPSTAITT-WMKDGSNIRESPKHRFIADGKDRK---------LHIIDVQ 11181
Query: 513 PEDAGIFTCSARNDYGSATSTAQLVV 538
DAG +TC R TSTA+LVV
Sbjct: 11182 LSDAGEYTCVLRLGNKEKTSTAKLVV 11207
Score = 42.0 bits (97), Expect = 0.003
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A P F KL + E + L+C V+ + V+WF +G+E+ +P I + G
Sbjct: 11661 ADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSPKYSIKAD-GLRRI 11717
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
L I +A D G Y C G+D T A V +E
Sbjct: 11718 LKIKKADLKDKGEYVC----DCGTDKTKANVTVE 11747
Score = 42.0 bits (97), Expect = 0.003
Identities = 61/251 (24%), Positives = 94/251 (37%), Gaps = 50/251 (19%)
Query: 783 LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 842
LK ++ E V F C V K WF++ + I S + +Q+DL +L +
Sbjct: 12646 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDL--VYTLRIRDAH 12702
Query: 843 LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENE 902
LDD NY V N RG + +S + N
Sbjct: 12703 LDDQANYN-----------------VSLTNHRGENVKSAA------------------NL 12727
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
++E R ++ D+ E K CKV+ L L W +G+ V D+ V
Sbjct: 12728 IVEEEDLR--IVEPLKDIETMEKKSVTFWCKVNRL-NVTLKWTKNGEEVPFDNRVSYRV- 12783
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVA 1022
+ H L I+ D G Y I T AGQ+ EL++ P F+E L++ V
Sbjct: 12784 DKYKHMLTIKDCGFPDEGEY--IVT--AGQDKSVAELLI----IEAPTEFVEHLEDQTVT 12835
Query: 1023 DGYPVRLECRV 1033
+ C++
Sbjct: 12836 EFDDAVFSCQL 12846
Score = 42.0 bits (97), Expect = 0.003
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFED 337
R Q + G + L + G P P+V W E ++ I + G L I A +
Sbjct: 17226 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLE---IRNAAHE 17282
Query: 338 DTGRYTCLATNPSGSDTTSAEVFI 361
D G Y+ NP+GS T S +V +
Sbjct: 17283 DGGIYSLTVENPAGSKTVSVKVLV 17306
Score = 42.0 bits (97), Expect = 0.003
Identities = 42/170 (24%), Positives = 73/170 (42%), Gaps = 13/170 (7%)
Query: 939 TPDLSWQLDGKPVRPDS---AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSF 995
+P+LS+ ++ + D HK ++E +++ + N G++ +
Sbjct: 18130 SPNLSYHVERRLKGSDDWERVHKGSIKET---HYMVDRCVENQIYEFRVQTKNEGGESDW 18186
Query: 996 SLELVVAAKEAHKPPVFIEKLQNT-GVADGYPVRLECRVLGVPPPQIFWKKENES--LTH 1052
V KE + PV KL V G +RLE V G P P++ W K+ ++ LT
Sbjct: 18187 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 18246
Query: 1053 STD-RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
S ++ D+ + + A + D G Y V+A N AG A ++V
Sbjct: 18247 SPRVKIDTRADSSKF---SLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNS-FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
+I +T + ++ +A N G++ SL + + AK+ P + V G ++
Sbjct: 23189 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 23248
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
+E + G P P I W K+ L +T R+++ D+ L I+ K+D G Y ++ N
Sbjct: 23249 IEVPISGRPKPTITWTKDGLPLKQTT-RINV-TDSLDLTTLSIKETHKDDGGQYGITVAN 23306
Query: 1089 EAG 1091
G
Sbjct: 23307 VVG 23309
Score = 41.6 bits (96), Expect = 0.004
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSR- 977
D+ V EG+ + +P P +SW DGK V+ ++ ++ ++ + + + + P + R
Sbjct: 14395 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK--ASDRLTMKNDHISAHLEVPKSVRA 14452
Query: 978 DAGIYTCIATNRAGQNSFSLELVV 1001
DAGIYT N+ G + S+ + V
Sbjct: 14453 DAGIYTITLENKLGSATASINVKV 14476
Score = 41.6 bits (96), Expect = 0.004
Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
P + KE V EG V + +++G P + WF+ + D+ + +L +
Sbjct: 16118 PSIDLKEFME--VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLV 16174
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ CTLVI ++ D G++T +A N+ G+A+ +L V
Sbjct: 16175 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 16213
Score = 41.6 bits (96), Expect = 0.004
Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 12/100 (12%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE------- 972
+ V+EG + K+ G+P P L+W P +PD+ +L + V+ L+++
Sbjct: 16126 MEVEEGTNVNIVAKIKGVPFPTLTW-FKAPPKKPDNKEPVLY-DTHVNKLVVDDTCTLVI 16183
Query: 973 PVTSR-DAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV 1011
P + R D G+YT A N G S + L V + PPV
Sbjct: 16184 PQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPG--PPV 16221
Score = 41.6 bits (96), Expect = 0.004
Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 4/82 (4%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL-IQGATKEDA 1079
V G V L+ V G P P + WKK+ +L + + M + +C L + ++D+
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRN--LCTLELFSVNRKDS 19363
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G YT++A+N +G S T +L V
Sbjct: 19364 GDYTITAENSSGSKSATIKLKV 19385
Score = 41.2 bits (95), Expect = 0.005
Identities = 35/149 (23%), Positives = 64/149 (42%), Gaps = 17/149 (11%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V AVN++GRS G P + R E +P E F ++A L
Sbjct: 25368 VAAVNEKGRSDPRQLGVPVIAR--------DIEIKPSVELPFHTFNVKAREQL------- 25412
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIAT 987
++D G P ++W+ DG+ ++ ++ + V SL I+ + D G Y +
Sbjct: 25413 -KIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 25470
Query: 988 NRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
N AG + + ++V + P+ I+++
Sbjct: 25471 NSAGSITVPITIIVLDRPGPPGPIRIDEV 25499
Score = 41.2 bits (95), Expect = 0.005
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
Query: 1000 VVAAKEAHKPPVFI---EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDR 1056
++ ++ + PP+ E + G +R++ V G P P++ W K+ + R
Sbjct: 27946 IIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEK---R 28002
Query: 1057 VSMH-QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
++M D G L ++ AT++ G YTV AKN +G ++ V
Sbjct: 28003 MNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 28048
Score = 41.2 bits (95), Expect = 0.005
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
GS ++ ++G P P+V W E L T + I D TL + ++ D+GRY
Sbjct: 28662 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYFL 28720
Query: 345 LATNPSGSDTTSAEVFIEG 363
N +G T S V + G
Sbjct: 28721 TLENTAGVKTFSVTVVVIG 28739
Score = 40.8 bits (94), Expect = 0.007
Identities = 56/240 (23%), Positives = 91/240 (37%), Gaps = 55/240 (22%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P +E L+ + EG T TC+ + P K WF++G+ + P+ H T +++
Sbjct: 8745 PAWERHLQDVTLKEGQTCTMTCQFSV-PNVKSEWFRNGRILKPQGRHKT---EVEHKVHK 8800
Query: 837 HTTAST-LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
T A +D G YT + + + L ++A
Sbjct: 8801 LTIADVRAEDQGQYTCKYED----LETSAELRIEA------------------------- 8831
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
EPIQ F + ++ V E + +C+VS ++W P
Sbjct: 8832 ------EPIQ-------FTKRIQNIVVSEHQSATFECEVS-FDDAIVTWYKG--PTELTE 8875
Query: 956 AHKMLVRENG-VHSLIIEPVTSRDAGIYTCIA-TNRAGQNSFSLELVVAAKEAH---KPP 1010
+ K R +G H + I VT D G+Y+ IA G+ + EL + KE KPP
Sbjct: 8876 SQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKPP 8935
Score = 40.8 bits (94), Expect = 0.007
Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 20/205 (9%)
Query: 678 DAVIQDLERK---LRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQE 734
D + D RK + +K N G P + Y M +G + N + ++ +
Sbjct: 14290 DLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP--VGTEKWMRVNSRPIKD----LK 14343
Query: 735 YKVSSCEQRLISEIEYRLERSPVDESG----DEVQYGDVPVENGMAPFFEMKLKHYKIFE 790
+KV E+ ++ + EY L V+ G E+ V + P +++ + E
Sbjct: 14344 FKV---EEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIE 14400
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G ++ P P + W KDGK++ SD T++ D + L S D G YT
Sbjct: 14401 GEKLSIPVPFRAVPVPTVSWHKDGKEVK-ASDRLTMKND-HISAHLEVPKSVRADAGIYT 14458
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
I N G S T + V+ + G
Sbjct: 14459 ITLENKLG--SATASINVKVIGLPG 14481
Score = 40.8 bits (94), Expect = 0.007
Identities = 32/106 (30%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRV 1057
E VVA KP + +E + V +G + + VP P + W K+ + + S DR+
Sbjct: 14376 ENVVAKDPDCKPTIDLET-HDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKAS-DRL 14433
Query: 1058 SMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
+M D H L + + + DAG YT++ +N+ G S TA ++V +
Sbjct: 14434 TMKND-HISAHLEVPKSVRADAGIYTITLENKLG--SATASINVKV 14476
Score = 40.8 bits (94), Expect = 0.007
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P E + V EG+ + + R P V W + G E++ S R+ K +A
Sbjct: 14387 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD--RLTMKNDHISAH- 14443
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L + ++ DAGI+T + N GSAT++ + V
Sbjct: 14444 -----LEVPKSVRADAGIYTITLENKLGSATASINVKV 14476
Score = 40.8 bits (94), Expect = 0.007
Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 8/100 (8%)
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFK------DGKQISPKSDHYTIQR 828
M P ++K + ++ EG V ++ G P P + WFK D K+ H +
Sbjct: 16116 MPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KL 16173
Query: 829 DLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
+D TC+L S D G YTI A N G S RL V
Sbjct: 16174 VVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 16213
Score = 40.4 bits (93), Expect = 0.009
Identities = 52/218 (23%), Positives = 83/218 (38%), Gaps = 51/218 (23%)
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
+GG T + EA + T R+ + T +E ++ ++ E F+ RA
Sbjct: 29661 DGGSRLTGYVLEACKAGTERWMKVVT--------LKPTVLEHTVTSLNEGEQYLFRIRA- 29711
Query: 382 AMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP 441
Q +K G S P+ VT +Q L V PT L
Sbjct: 29712 ---QNEK---------GVSEPRETVTAVTVQDLRV------LPTIDLS------------ 29741
Query: 442 VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
T + V G+ V L + G PP WF GS++++S R T E
Sbjct: 29742 --TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRES---------ERVTVETH 29790
Query: 502 -EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ L I ET D G +T +N G+ + T ++++
Sbjct: 29791 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVII 29828
Score = 40.0 bits (92), Expect = 0.012
Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G T R +G PKPK+ WFKD + D T + T +L + D G Y
Sbjct: 16833 GEAFALTGRYSGKPKPKVSWFKDEADV--LEDDRTHIKTTPATLALEKIKAKRSDSGKYC 16890
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
++ N G S G V V++ G
Sbjct: 16891 VVVENSTG--SRKGFCQVNVVDRPG 16913
Score = 39.7 bits (91), Expect = 0.016
Identities = 74/339 (21%), Positives = 122/339 (35%), Gaps = 77/339 (22%)
Query: 758 DESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQI 817
D+S E+ + P E F L+ + E F+C+++ K + W+++G++I
Sbjct: 12810 DKSVAELLIIEAPTE------FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNGREI 12862
Query: 818 SPKSDHYTIQRDLDGTCSLHTTA---STLDDDGNYTIMAANPQGRISCTGRLMVQAVNQR 874
+ Y ++D S+H LDD+ Y + + R RL V+ +
Sbjct: 12863 K-EGKKYKFEKD----GSIHRLIIKDCRLDDECEYACGVEDRKSR----ARLFVEEI--- 12910
Query: 875 GRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRP--HFLQAPGDLTVQEGKLCRMDC 932
P++ RP L+APG V +L +
Sbjct: 12911 ----------------------------PVE--IIRPPQDILEAPGADVVFLAELNKDKV 12940
Query: 933 KVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQ 992
+V W + V H+M+ E +H L I + RD G Y IA ++ +
Sbjct: 12941 EVQ--------WLRNNMVVVQGDKHQMM-SEGKIHRLQICDIKPRDQGEYRFIAKDKEAR 12991
Query: 993 NSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTH 1052
L K A Q+ V G P+ + P + W KENE L+
Sbjct: 12992 AKLELAAAPKIKTAD---------QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLST 13042
Query: 1053 STDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
T + Q + I A K D G Y + +N+ G
Sbjct: 13043 KTIDTTAEQTS-----FRILEAKKGDKGRYKIVLQNKHG 13076
Score = 39.7 bits (91), Expect = 0.016
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
++ G + + VTG P P W E EL D + G LII +A D G
Sbjct: 15115 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDK--DRVVIDNVGTKSELIIKDALRKDHG 15172
Query: 341 RYTCLATNPSGSDTTSAEV 359
RY ATN GS +A V
Sbjct: 15173 RYVITATNSCGSKFAAARV 15191
Score = 39.7 bits (91), Expect = 0.016
Identities = 41/146 (28%), Positives = 60/146 (41%), Gaps = 24/146 (16%)
Query: 865 RLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQE 924
R V+AVN+ G S P + D +E E + + A L +
Sbjct: 15778 RFRVKAVNEAGES------EPSDTTGEIPATDIQEEPEVFID-------IGAQDCLVCKA 15824
Query: 925 GKLCRMDCKVSGLPTPDLSWQLDGKPVR--PDSAH------KMLVRENGVHSLIIEPVTS 976
G R+ + G PTP SW+ DGK + D H ++ EN S+II P
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENS--SVIIIPECK 15882
Query: 977 RD-AGIYTCIATNRAGQNSFSLELVV 1001
R G Y+ A N+AGQ + + + V
Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKV 15908
Score = 39.7 bits (91), Expect = 0.016
Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 9/138 (6%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF-----IEKLQNTGVADG 1024
++ +T + + +A N AG+++ V KE P +KL D
Sbjct: 21023 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDN 21082
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
+++E VLG P P + WKK + + T RV+ I L I + D+G Y +
Sbjct: 21083 --IKVEIPVLGRPKPTVTWKK-GDQILKQTQRVNFETTATSTI-LNINECVRSDSGPYPL 21138
Query: 1085 SAKNEAGIVSCTARLDVY 1102
+A+N G V + V+
Sbjct: 21139 TARNIVGEVGDVITIQVH 21156
Score = 39.7 bits (91), Expect = 0.016
Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 7/125 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P + ++ K ++T V G +++ + G
Sbjct: 22511 FRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGK 22570
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
P P I W K ++ L++ T R+ + + L ++ A + D+G Y + AKN AG S T
Sbjct: 22571 PIPTIQWIKGDQELSN-TARLEIKSTDFA-TSLSVKDAVRVDSGNYILKAKNVAGERSVT 22628
Query: 1097 ARLDV 1101
+ V
Sbjct: 22629 VNVKV 22633
Score = 39.3 bits (90), Expect = 0.021
Identities = 42/174 (24%), Positives = 69/174 (39%), Gaps = 12/174 (6%)
Query: 688 LRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISE 747
L+++ + G P L+Y + RRL G+D + +E Y V C + I
Sbjct: 18119 LKWRRPDYDGGSPNLSYH--VERRLKGSDDWERVHKGSIKET----HYMVDRCVENQI-- 18170
Query: 748 IEYRLERSPVDESGDEVQYGDVPVENGMA-PFFEMKLKHY-KIFEGMPVTFTCRVAGNPK 805
E+R++ D V+ +V V+ + P ++KL + G + V G P
Sbjct: 18171 YEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPF 18230
Query: 806 PKIYWFKDGKQIS-PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQG 858
P++ W KD +S I D + T + D G Y + A N G
Sbjct: 18231 PEVAWTKDKDATDLTRSPRVKIDTRADSS-KFSLTKAKRSDGGKYVVTATNTAG 18283
Score = 39.3 bits (90), Expect = 0.021
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI-IEPVTSRD 978
+ V+ G++ +++ ++G P P +SW DG + + +++ +N H+L+ ++ RD
Sbjct: 25799 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN--HTLLTVKDCIRRD 25856
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAK 1004
G Y N AG S ++ V K
Sbjct: 25857 TGQYVLTLKNVAGTRSVAVNCKVLDK 25882
Score = 38.9 bits (89), Expect = 0.027
Identities = 63/282 (22%), Positives = 102/282 (36%), Gaps = 24/282 (8%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
I L+ V EG++ LEC+V+ V+W+ +++ +Q + G L+I
Sbjct: 2448 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK-GTKQRLVINR 2506
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASS-TDSDSESLAFK---SRAGAMPQAQ 387
D G Y + + S E I G T ++++++ F+ S +G
Sbjct: 2507 THASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWN 2566
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPV----F 443
K + SS I L+V Y T+ V
Sbjct: 2567 FKDKEIK----PSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAI 2622
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
+K L + VAE Q V EC V P + +W R G + L RS ++ +
Sbjct: 2623 SKPLTDQTVAESQEAVFECEVAN-PDSKGEWLRDGKHLP-------LTNNIRSESDGHK- 2673
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTEN 545
L+IA T +D G +T SA + V +N
Sbjct: 2674 RRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKN 2715
Score = 38.9 bits (89), Expect = 0.027
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGK--ELHNTPDIQIHCEGGDLHTLI 330
F+ + +S V E + +V G+P P V+W +GK +L+ + IH + GD L
Sbjct: 8456 FVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW-TKGKWRQLNQGGRVFIH-QKGDEAKLE 8513
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
I + + D+G Y C+A N G ++ + ++
Sbjct: 8514 IRDTTKTDSGLYRCVAFNEHGEIESNVNLQVD 8545
Score = 38.9 bits (89), Expect = 0.027
Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 10/104 (9%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWF------CEGKE--LHNTPDIQI 319
P P I EV EG+ V + ++ G P P + WF + KE L++T ++
Sbjct: 16114 PDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKL 16173
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
+ D TL+I ++ DTG YT A N G+ + + + G
Sbjct: 16174 VVD--DTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 16215
Score = 38.9 bits (89), Expect = 0.027
Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 22/125 (17%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V GQ + + RV+G P + W ++G + ++Q PR L I E
Sbjct: 17920 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPR--------VELQIKEA 17971
Query: 512 FPEDAGIFTCSARNDYGSATSTA------------QLVVTSANTENC--SYESMGESNND 557
D G + SA+N G A +A L VT+ ENC S+E+ ++
Sbjct: 17972 VRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGS 18031
Query: 558 HFQHF 562
+F
Sbjct: 18032 EITNF 18036
Score = 38.9 bits (89), Expect = 0.027
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F TV G+ ++D G PTP ++W D P++ + EN L
Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN-SLLT 22206
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
I+ D G Y TN AG+ +L ++V K
Sbjct: 22207 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 22240
Score = 38.9 bits (89), Expect = 0.027
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 768 DVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ 827
D+ +E + P F Y + G + ++G PKP I W KDG + ++ +
Sbjct: 23225 DLVIEPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINVT 23279
Query: 828 RDLDGTCSLHTTASTLDDDGNYTIMAANPQGR 859
LD T +L + DD G Y I AN G+
Sbjct: 23280 DSLDLT-TLSIKETHKDDGGQYGITVANVVGQ 23310
Score = 38.9 bits (89), Expect = 0.027
Identities = 35/139 (25%), Positives = 50/139 (35%), Gaps = 24/139 (17%)
Query: 227 QGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGS 286
+ + E+ V P QDL V P +H PA G
Sbjct: 29710 RAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPA---------------GR 29754
Query: 287 RVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT----LIIAEAFEDDTGRY 342
V L + G P P WF G +L + + + + HT L I E DTG Y
Sbjct: 29755 PVELVIPIAGRPPPAASWFFAGSKLRESERVTV-----ETHTKVAKLTIRETTIRDTGEY 29809
Query: 343 TCLATNPSGSDTTSAEVFI 361
T N +G+ + + +V I
Sbjct: 29810 TLELKNVTGTTSETIKVII 29828
Score = 38.5 bits (88), Expect = 0.036
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKE-------LHNTPDIQIHCEGGDLHTLIIAEAFED 337
GS++ + + G PTP+ W +GK +H+ P+ + +II E
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 15884
Query: 338 DTGRYTCLATNPSGSDTTSAEV 359
TG+Y+ A N +G T + V
Sbjct: 15885 HTGKYSITAKNKAGQKTANCRV 15906
Score = 38.5 bits (88), Expect = 0.036
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 13/129 (10%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLE---LVVAAKEAHKPPVFIE-KLQNTGVAD-GY 1025
+ +T A + IA N AG S E + + P + ++ K ++T + G
Sbjct: 21418 VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGE 21477
Query: 1026 PVRLECRVLGVPPPQIFWKKENESLTHSTD---RVSMHQDNHGYICLLIQGATKEDAGWY 1082
RLE V G PPP + W K+ + L + +++ N L+ + +T+ D+G Y
Sbjct: 21478 AFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN-----LVNKDSTRRDSGAY 21532
Query: 1083 TVSAKNEAG 1091
T++A N G
Sbjct: 21533 TLTATNPGG 21541
Score = 38.5 bits (88), Expect = 0.036
Identities = 37/159 (23%), Positives = 65/159 (40%), Gaps = 18/159 (11%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V G+ + ++G P P SW G +R +S + V L I T RD G
Sbjct: 29750 VPAGRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTVETHTKVAKLTIRETTIRDTGE 29808
Query: 982 YTCIATNRAGQNSFSLELVVAAKEAHKP-PVFIEKLQNTGVADGY-PVRLECRVLGVPPP 1039
YT N G S ++++++ K P+ I+++ T + + P L+ G P
Sbjct: 29809 YTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPL 29864
Query: 1040 QIF-----------WKKENESLTHSTDRVSMHQDNHGYI 1067
+ W +ES+T ST + + + + Y+
Sbjct: 29865 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYV 29903
Score = 38.1 bits (87), Expect = 0.046
Identities = 59/300 (19%), Positives = 106/300 (35%), Gaps = 48/300 (16%)
Query: 79 PSHKETKLGEHASRRPQDNRSTPVQPLAEKQTKSISSPVSKRKPAMSPL--LTRPSYIRS 136
P KE + + R+ + V+P K+ + + P P P+ + P+ +
Sbjct: 10941 PEPKEEVVLKSVLRKRPEEEEPKVEP---KKLEKVKKPAVPEPPPPKPVEEVEVPTVTKR 10997
Query: 137 LRKAE--------KRGAKTPSTNVKPKTPHQRKGGPQSQLCDKAANLIEELTSIFKAAKP 188
RK K P+ KPK + K + + + +T K
Sbjct: 10998 ERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKA 11057
Query: 189 RNRSPNGESSSPDSGYLS-PKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQ 247
++P E++ P PK PS + E ER PG+
Sbjct: 11058 EAKAPKEEAAKPKGPIKGVPKKTPSPI--------------EAERRKLRPGSG------- 11096
Query: 248 DLAVPHNRKSHPQPHSALHFPAAP-RFIQKLRSQEVAE----GSRVYLECRVTGNPTPRV 302
K + A P +F+++++ + E GS EC V+ + T
Sbjct: 11097 ------GEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPS-TAIT 11149
Query: 303 RWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
W +G + +P + +G D L I + D G YTC+ + T++A++ +E
Sbjct: 11150 TWMKDGSNIRESPKHRFIADGKD-RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 11208
Score = 38.1 bits (87), Expect = 0.046
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 8/114 (7%)
Query: 982 YTCIATNRAGQNSFS-LELVVAAKEAHKPPVFI---EKLQNTGVADGYPVRLECRVLGVP 1037
+ +A N AG++ + + V K+ +PP I + + G +RL + GVP
Sbjct: 17187 FRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVP 17246
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
P++ WKKE+ + R+ + L I+ A ED G Y+++ +N AG
Sbjct: 17247 FPKVTWKKEDRD-APTKARIDVTPVGSK---LEIRNAAHEDGGIYSLTVENPAG 17296
Score = 38.1 bits (87), Expect = 0.046
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G+ V L+ V G P P V W +G L I++ + +L TL + D+G
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQ-RNLCTLELFSVNRKDSGD 19365
Query: 342 YTCLATNPSGSDTTSAEV 359
YT A N SGS + + ++
Sbjct: 19366 YTITAENSSGSKSATIKL 19383
Score = 38.1 bits (87), Expect = 0.046
Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Query: 920 LTVQEGKLCRMDC-KVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
LT++ G ++ + G P P SW GK +RP ++ L I+ T +D
Sbjct: 20388 LTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKD 20446
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
AG YT ATN G +++ V PV I +
Sbjct: 20447 AGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNV 20484
Score = 38.1 bits (87), Expect = 0.046
Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ GS + L+ V G P P++ W KEL + + G T +I D+G+
Sbjct: 29059 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYT-GKRATAVIKFCDRSDSGK 29117
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SG+ S V
Sbjct: 29118 YTLTVKNASGTKAVSVMV 29135
Score = 37.7 bits (86), Expect = 0.061
Identities = 50/218 (22%), Positives = 81/218 (37%), Gaps = 46/218 (21%)
Query: 783 LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 842
L K+ EG V +V+ + W KDG+++ P SD I D L T
Sbjct: 2362 LSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQP-SDRVHIVIDKQSHMLL-IEDMT 2418
Query: 843 LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENE 902
+D GNY+ P +S +GR+ V +V D
Sbjct: 2419 KEDAGNYSFTI--PALGLSTSGRVSVYSV---------------------------DVIT 2449
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
P++ D+ V EG ++CKVS + W L+ + ++PD + +V+
Sbjct: 2450 PLK-------------DVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK 2496
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 1000
L+I + D G Y I + S+E +
Sbjct: 2497 -GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKI 2533
Score = 37.7 bits (86), Expect = 0.061
Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 8/87 (9%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G V L+ V G P V W + G+ ++ + ++ ++ +CTL +
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR--------NLCTLELFSV 19358
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVV 538
+D+G +T +A N GS ++T +L V
Sbjct: 19359 NRKDSGDYTITAENSSGSKSATIKLKV 19385
Score = 37.4 bits (85), Expect = 0.079
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWF--CEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDT 339
V G + LE V G P P V W + +L +P ++I D + +A D
Sbjct: 18213 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTR-ADSSKFSLTKAKRSDG 18271
Query: 340 GRYTCLATNPSGSDTTSAEV 359
G+Y ATN +GS A V
Sbjct: 18272 GKYVVTATNTAGSFVAYATV 18291
Score = 37.0 bits (84), Expect = 0.10
Identities = 47/218 (21%), Positives = 90/218 (41%), Gaps = 34/218 (15%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G+ V + V G P +++W + + I+ D + K+ S +E + L I +
Sbjct: 15410 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAK--TELSIPKA 15467
Query: 512 FPEDAGIFTCSARNDYGSA------------TSTAQLVVTSANTENC--SYESMGESNND 557
ED G +T +A N GS + L VT E+C ++++ ++
Sbjct: 15468 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGS 15527
Query: 558 HFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSR 617
H+ +++ AS+K +E ++V N A++ ++ + NG + R
Sbjct: 15528 EITHY-----VIDKRD---ASRKKAEWEEVTN-------TAVEKRYGIWKLIPNGQYEFR 15572
Query: 618 GVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKL 655
+N S++ V+ P + P P KPK+
Sbjct: 15573 --VRAVNKYGISDECKSDKVVIQDPYRLPGP-PGKPKV 15607
Score = 37.0 bits (84), Expect = 0.10
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL-IQGATKEDAGWY 1082
G +RL V G PPP+I W K N +L DR+ + + + L + K DAG Y
Sbjct: 19708 GVTMRLYVPVKGRPPPKITWSKPNVNL---RDRIGLDIKSTDFDTFLRCENVNKYDAGKY 19764
Query: 1083 TVSAKNEAG 1091
++ +N G
Sbjct: 19765 ILTLENSCG 19773
Score = 37.0 bits (84), Expect = 0.10
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 923 QEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH-SLIIEPVTSRDAGI 981
+E R+ + G P P +SW+ P+ D+ ++ V + V+ +LI+ DAG
Sbjct: 19995 KENSNFRLKIPIKGKPAPSVSWKKGEDPLATDT--RVSVESSAVNTTLIVYDCQKSDAGK 20052
Query: 982 YTCIATNRAGQNSFSLELVVAAK 1004
YT N AG ++ + V K
Sbjct: 20053 YTITLKNVAGTKEGTISIKVVGK 20075
Score = 37.0 bits (84), Expect = 0.10
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQG 858
V+G P P + W KDGK++ + + D + +L ST D G YT+ A NP G
Sbjct: 21485 VSGRPPPTMEWSKDGKELEGTAKLEI--KIADFSTNLVNKDSTRRDSGAYTLTATNPGG 21541
Score = 37.0 bits (84), Expect = 0.10
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 10/121 (8%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ R++ V G P P + W K + +SA + + LI++ D
Sbjct: 23635 IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIE-ESARCEIKNTDFKALLIVKDAIRIDG 23693
Query: 980 GIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPP 1039
G Y A+N AG SF + + V + PP +Q TGV +C + PP
Sbjct: 23694 GQYILRASNVAGSKSFPVNVKVLDRPG--PPE--GPVQVTGVTSE-----KCSLTWSPPL 23744
Query: 1040 Q 1040
Q
Sbjct: 23745 Q 23745
Score = 37.0 bits (84), Expect = 0.10
Identities = 29/125 (23%), Positives = 57/125 (45%), Gaps = 3/125 (2%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNS-FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
I +T+ + ++ A N G++ L + V A++ P V +++
Sbjct: 25355 ISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKI 25414
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
+ G P + W+K+ ++L +T RV++ + L I+ A+KED G Y + N
Sbjct: 25415 DVPFKGRPQATVNWRKDGQTLKETT-RVNV-SSSKTVTSLSIKEASKEDVGTYELCVSNS 25472
Query: 1090 AGIVS 1094
AG ++
Sbjct: 25473 AGSIT 25477
Score = 37.0 bits (84), Expect = 0.10
Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 14/86 (16%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLT-----HSTDRVSMHQDNHGYICLLIQGAT 1075
V G +RL G P P W K + +L+ H+TD S L ++
Sbjct: 28369 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST---------LTVENCN 28419
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDV 1101
+ DAG YT++ +N +G S T + V
Sbjct: 28420 RNDAGKYTLTVENNSGSKSITFTVKV 28445
Score = 37.0 bits (84), Expect = 0.10
Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Query: 781 MKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA 840
M K + G PV +AG P P WF G ++ +S+ T++ L
Sbjct: 29743 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTVETHTK-VAKLTIRE 29800
Query: 841 STLDDDGNYTIMAANPQGRISCTGRLMV 868
+T+ D G YT+ N G S T ++++
Sbjct: 29801 TTIRDTGEYTLELKNVTGTTSETIKVII 29828
Score = 36.6 bits (83), Expect = 0.14
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 10/178 (5%)
Query: 193 PNGESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVP 252
P +SPD G+ N + L+ + + +++ E E V C Q+ + P
Sbjct: 18537 PKIADASPDEGW-KRCNAAAQLVRKEFTVTSLDENQEYEFRV-------CAQNQVGIGRP 18588
Query: 253 HNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELH 312
K +P L P + V G + L V G P P+V W G + +
Sbjct: 18589 AELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-N 18647
Query: 313 NTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSD 370
Q+ + L+I + DD+G+Y+ NP+G V + SD
Sbjct: 18648 VVRKGQVDLVD-TMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 18704
Score = 36.6 bits (83), Expect = 0.14
Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P + ++ K ++T V + G RLE V G
Sbjct: 23593 FRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGK 23652
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
P P I W + ++ + S + D L+++ A + D G Y + A N AG S
Sbjct: 23653 PLPTIEWLRGDKEIEESARCEIKNTDFKA--LLIVKDAIRIDGGQYILRASNVAGSKSFP 23710
Query: 1097 ARLDV 1101
+ V
Sbjct: 23711 VNVKV 23715
Score = 36.6 bits (83), Expect = 0.14
Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
G+ V L ++G P P + W+ + KEL + + DL +++I +A ++G Y
Sbjct: 26887 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRLNSGCYEL 26945
Query: 345 LATNPSGSDTTSAEVFI 361
N GS + + V I
Sbjct: 26946 KLRNAMGSASATIRVQI 26962
Score = 36.6 bits (83), Expect = 0.14
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 5/103 (4%)
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHK 958
DEN P F +F L ++ G+ R+ V G P P ++W DG + +
Sbjct: 27951 DENVPPIVEFGPEYF----DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMNM 28005
Query: 959 MLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+ G SL + T G+YT A N +G +++ V
Sbjct: 28006 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 28048
Score = 36.6 bits (83), Expect = 0.14
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC-LLIQGATKEDA 1079
V G PV L + G PPP W L S +RV++ + H + L I+ T D
Sbjct: 29750 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRES-ERVTV--ETHTKVAKLTIRETTIRDT 29806
Query: 1080 GWYTVSAKNEAGIVSCTARL 1099
G YT+ KN G S T ++
Sbjct: 29807 GEYTLELKNVTGTTSETIKV 29826
Score = 36.6 bits (83), Expect = 0.14
Identities = 20/97 (20%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V++G + R+ + G P P W +G+ + S M+ L+I+ D+G
Sbjct: 30148 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI---SKRAMIATSETHTELVIKEADRGDSGT 30204
Query: 982 YTCIATNRAGQNSFSLEL-VVAAKEAHKPPVFIEKLQ 1017
Y + N+ G+ + +++ V+ + + + P+ + +Q
Sbjct: 30205 YDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQ 30241
Score = 36.2 bits (82), Expect = 0.18
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 1/86 (1%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
++ L V G+++ L VTG P P++ W L I I T+ I +
Sbjct: 13694 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVD 13752
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAEV 359
+ DTG Y A N G T EV
Sbjct: 13753 SKRSDTGTYIIEAVNVCGRATAVVEV 13778
Score = 36.2 bits (82), Expect = 0.18
Identities = 39/169 (23%), Positives = 59/169 (34%), Gaps = 22/169 (13%)
Query: 824 YTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG 883
Y + + L GT + YT+ R +L V AVN G P +
Sbjct: 15036 YFVDKQLVGTNEWSRCTEKMIKVRQYTVKEI----REGADYKLRVSAVNAAGEGPPGETQ 15091
Query: 884 HPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLS 943
V P+ D + G + + GK R+ V+G P P
Sbjct: 15092 PVTVAEPQEPPAVELD--------------VSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 15137
Query: 944 WQLDGKPVRPDSAHKMLVRENGVHS-LIIEPVTSRDAGIYTCIATNRAG 991
W + + D ++++ G S LII+ +D G Y ATN G
Sbjct: 15138 WTKEEGELDKD---RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCG 15183
Score = 36.2 bits (82), Expect = 0.18
Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 9/123 (7%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKK 1045
A N AG + S + + P I+ + V +G V + ++ GVP P + W K
Sbjct: 16093 AVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 16152
Query: 1046 -------ENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTAR 1098
E + + T + D+ L+I + + D G YT++A N G S R
Sbjct: 16153 APPKKPDNKEPVLYDTHVNKLVVDDT--CTLVIPQSRRSDTGLYTITAVNNLGTASKEMR 16210
Query: 1099 LDV 1101
L+V
Sbjct: 16211 LNV 16213
Score = 36.2 bits (82), Expect = 0.18
Identities = 20/94 (21%), Positives = 36/94 (38%), Gaps = 1/94 (1%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P+ ++ + V G+ V + G P P +W +G E+ + +
Sbjct: 17508 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS-S 17566
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
L I DTG Y +N +GS T + + +
Sbjct: 17567 VLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 36.2 bits (82), Expect = 0.18
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G P ++ + G P P++ WK E E TDRVS+ L ++ + + D+G Y
Sbjct: 28662 GSPFTIDVPISGRPAPKVTWKLE-EMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYF 28719
Query: 1084 VSAKNEAGI 1092
++ +N AG+
Sbjct: 28720 LTLENTAGV 28728
Score = 35.8 bits (81), Expect = 0.23
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A F++ L Q V E C+++ V+W+ G+E+ + + G +H
Sbjct: 12821 APTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKKYKFE-KDGSIHR 12878
Query: 329 LIIAEAFEDDTGRYTC 344
LII + DD Y C
Sbjct: 12879 LIIKDCRLDDECEYAC 12894
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 11/127 (8%)
Query: 732 NQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEG 791
NQEY+ C Q + I E + + ++ ++ ++ M ++ G
Sbjct: 18570 NQEYEFRVCAQNQVG-IGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRA-------G 18621
Query: 792 MPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTI 851
P+ V G P PK+ W K G + + +D L ST DD G Y++
Sbjct: 18622 CPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL---VDTMAFLVIPNSTRDDSGKYSL 18678
Query: 852 MAANPQG 858
NP G
Sbjct: 18679 TLVNPAG 18685
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 12/109 (11%)
Query: 992 QNSFSLELVVAAKEAHKPPVFIEKLQN---------TGVADGYPVRLECRVLGVPPPQIF 1042
QN + KEA KP +E + V G P+RL V G P P++
Sbjct: 18580 QNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVT 18639
Query: 1043 WKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
W+K +V + D + L+I +T++D+G Y+++ N AG
Sbjct: 18640 WRKVGIDNVVRKGQVDL-VDTMAF--LVIPNSTRDDSGKYSLTLVNPAG 18685
Score = 35.8 bits (81), Expect = 0.23
Identities = 19/82 (23%), Positives = 35/82 (42%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ ++ + G P PD+ W DGK + +A + +L+++ D
Sbjct: 24717 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 24776
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y +N G S + + V
Sbjct: 24777 GQYILKLSNVGGTKSIPITVKV 24798
Score = 35.8 bits (81), Expect = 0.23
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V+ G ++D +SG P P ++ DG P++ + + + E VT+ DAG
Sbjct: 26488 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTA-DAGR 26546
Query: 982 YTCIATNRAGQNSFSLELVV 1001
Y A N +G + +VV
Sbjct: 26547 YEITAANSSGTTKAFINIVV 26566
Score = 35.4 bits (80), Expect = 0.30
Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 986 ATNRAGQNSF---SLELVVAAKEAHKPPVFIEKLQNTGV---ADGYPVRLECRVLGVPPP 1039
A N AG S S E ++ E P + ++ G+ A V +LG P P
Sbjct: 20350 AKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLP 20409
Query: 1040 QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
+ W K + + S ++ L I+ AT++DAG YT++A N G
Sbjct: 20410 KSSWSKAGKDIRPSD--ITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 20459
Score = 35.4 bits (80), Expect = 0.30
Identities = 24/60 (40%), Positives = 27/60 (45%), Gaps = 4/60 (6%)
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA-STLDDDGNYTIMAANPQG 858
+ G P PK W K GK I P Q T S+ T +T D G YTI A NP G
Sbjct: 20403 ILGKPLPKSSWSKAGKDIRPSD---ITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 20459
Score = 35.4 bits (80), Expect = 0.30
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V G ++ + G P P ++W +EL NT ++I + D T L + +A D+G
Sbjct: 22555 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEI--KSTDFATSLSVKDAVRVDSG 22612
Query: 341 RYTCLATNPSGSDTTSAEV 359
Y A N +G + + V
Sbjct: 22613 NYILKAKNVAGERSVTVNV 22631
Score = 35.4 bits (80), Expect = 0.30
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V G LE V G P P + W KE+ + +I + D LI+ +A D G
Sbjct: 23637 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI--KNTDFKALLIVKDAIRIDGG 23694
Query: 341 RYTCLATNPSGSDTTSAEV 359
+Y A+N +GS + V
Sbjct: 23695 QYILRASNVAGSKSFPVNV 23713
Score = 35.4 bits (80), Expect = 0.30
Identities = 20/85 (23%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+T + G +D +SG P P ++W+L+ ++ + ++ +L ++ D+
Sbjct: 28657 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRT-TLTVKDSMRGDS 28715
Query: 980 GIYTCIATNRAGQNSFSLELVVAAK 1004
G Y N AG +FS+ +VV +
Sbjct: 28716 GRYFLTLENTAGVKTFSVTVVVIGR 28740
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V EG ++ + P P V W +GKE+ + + + + H L + ++ D G
Sbjct: 14398 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGI 14456
Query: 342 YTCLATNPSGSDTTSAEVFIEG 363
YT N GS T S V + G
Sbjct: 14457 YTITLENKLGSATASINVKVIG 14478
Score = 35.0 bits (79), Expect = 0.39
Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS-LIIEPVTSRDAG 980
++ G R+ + G+P P ++W+ + + D+ K + V S L I D G
Sbjct: 17230 IKVGDTLRLSAIIKGVPFPKVTWKKEDR----DAPTKARIDVTPVGSKLEIRNAAHEDGG 17285
Query: 981 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIE 1014
IY+ N AG + S++++V K PP +E
Sbjct: 17286 IYSLTVENPAGSKTVSVKVLVLDKPG--PPRDLE 17317
Score = 35.0 bits (79), Expect = 0.39
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 17/80 (21%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH--------SLII 971
+TV+ G+ R+ +V G P PD++W +G K+LVRE V L I
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEG---------KVLVREKRVDLIQDLPRVELQI 17968
Query: 972 EPVTSRDAGIYTCIATNRAG 991
+ D G Y A N +G
Sbjct: 17969 KEAVRADHGKYIISAKNSSG 17988
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F + V G + ++ G PTP V W + L T +++ E + ++L+
Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQT--TRVNAESTENNSLL 22205
Query: 331 -IAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
I +A +D G Y TN +G + V +
Sbjct: 22206 TIKDACREDVGHYVVKLTNSAGEAIETLNVIV 22237
Score = 35.0 bits (79), Expect = 0.39
Identities = 21/71 (29%), Positives = 29/71 (40%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G LE + G P P V W +GKEL T TL++ + D G+
Sbjct: 24719 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778
Query: 342 YTCLATNPSGS 352
Y +N G+
Sbjct: 24779 YILKLSNVGGT 24789
Score = 35.0 bits (79), Expect = 0.39
Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 4/118 (3%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGVPPPQIFW 1043
A + + S S ++ + P V ++ K ++ V G +++ + G P P I W
Sbjct: 25764 AADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISW 25823
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
K+ + + DNH L ++ + D G Y ++ KN AG S V
Sbjct: 25824 AKDGIEIEERARTEIISTDNH--TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 25879
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V +G + L + G P P +W EG+++ I + HT L+I EA D+G
Sbjct: 30148 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIAT----SETHTELVIKEADRGDSG 30203
Query: 341 RYTCLATNPSGSDTTSAEVFIEGASST 367
Y + N G +V + G+ ++
Sbjct: 30204 TYDLVLENKCGKKAVYIKVRVIGSPNS 30230
Score = 34.7 bits (78), Expect = 0.51
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 10/94 (10%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTL-DDDGNY 849
G V F + G P P W DG +I +HYT+ + D S+ T + L D G Y
Sbjct: 17525 GTTVRFPAIIRGVPVPTAKWTTDGSEIK-TDEHYTV--ETDNFSSVLTIKNCLRRDTGEY 17581
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG 883
I +N G + L V V P P+G
Sbjct: 17582 QITVSNAAGSKTVAVHLTVLDV------PGPPTG 17609
Score = 34.7 bits (78), Expect = 0.51
Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G + + RV G P P + W EGK L + + + L I EA D G+
Sbjct: 17920 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL-IQDLPRVELQIKEAVRADHGK 17978
Query: 342 YTCLATNPSGSDTTSAEV 359
Y A N SG SA V
Sbjct: 17979 YIISAKNSSGHAQGSAIV 17996
Score = 34.7 bits (78), Expect = 0.51
Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G + RV G P+P I W K+GK + + + +DL L + D G Y
Sbjct: 17923 GQTIRILARVKGRPEPDITWTKEGK-VLVREKRVDLIQDLP-RVELQIKEAVRADHGKYI 17980
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
I A N G G +V +++ G
Sbjct: 17981 ISAKNSSGH--AQGSAIVNVLDRPG 18003
Score = 34.7 bits (78), Expect = 0.51
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Query: 294 VTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSD 353
+ G P P+ W GK++ + QI L I A D G YT ATNP G+
Sbjct: 20403 ILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKDAGEYTITATNPFGTK 20461
Query: 354 TTSAEVFI 361
+V +
Sbjct: 20462 VEHVKVTV 20469
Score = 34.7 bits (78), Expect = 0.51
Identities = 27/101 (26%), Positives = 52/101 (51%), Gaps = 7/101 (6%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSW-QLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
+ ++ G R+ + G PTP++ W ++DG+ +R D+A ++ + SL+++ V D
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGE-IR-DAA--IIDVTSSFTSLVLDNVNRYD 23007
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT 1019
+G YT N +G S + V + PPV ++ + T
Sbjct: 23008 SGKYTLTLENSSGTK--SAFVTVRVLDTPSPPVNLKVTEIT 23046
Score = 34.7 bits (78), Expect = 0.51
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 917 PG-DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
PG +TV+ G ++ G P P +SW DG P++ + EN + +L I+
Sbjct: 27569 PGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAK 27627
Query: 976 SRDAGIYTCIATN 988
G YT I N
Sbjct: 27628 KEHGGKYTVILDN 27640
Score = 34.3 bits (77), Expect = 0.67
Identities = 26/129 (20%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Query: 966 VHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF---IEKLQNTGVA 1022
+ ++ + +++ + A N AG ++ V E P F E + V
Sbjct: 20730 ITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVR 20789
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
G +R+ + G P P++ W K+N +L + + ++ + L+I + D G +
Sbjct: 20790 AGLSIRIFVPIKGRPAPEVTWTKDNINLKNRAN----IENTESFTLLIIPECNRYDTGKF 20845
Query: 1083 TVSAKNEAG 1091
++ +N AG
Sbjct: 20846 VMTIENPAG 20854
Score = 33.9 bits (76), Expect = 0.88
Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 3/92 (3%)
Query: 272 RFIQKLRSQ-EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
RF++ L + V +G +YL C + N V W +GK + P + G + L
Sbjct: 11213 RFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALT 11270
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
I +A + D G YT N + + +S +E
Sbjct: 11271 INDADDTDAGTYTVTVENANNLECSSCVKVVE 11302
Score = 33.9 bits (76), Expect = 0.88
Identities = 28/165 (16%), Positives = 63/165 (38%), Gaps = 15/165 (9%)
Query: 942 LSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN--SFSLEL 999
+++ L+ + + + HK+ ++ + D Y A N GQ SF +
Sbjct: 16749 INYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP 16808
Query: 1000 VVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESL--------- 1050
+ E P + ++ + G L R G P P++ W K+ +
Sbjct: 16809 ITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK 16868
Query: 1051 ----THSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
T + +++ + + G C++++ +T G+ V+ + G
Sbjct: 16869 TTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG 16913
Score = 33.9 bits (76), Expect = 0.88
Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS-LIIE 972
L+ G LTV+ G R++ V G P P+++W D + ++ + S +
Sbjct: 18205 LKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT 18264
Query: 973 PVTSRDAGIYTCIATNRAG 991
D G Y ATN AG
Sbjct: 18265 KAKRSDGGKYVVTATNTAG 18283
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 3/74 (4%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFED 337
R+ V G + + + G P P V W + L N +I+ + E L LII E
Sbjct: 20784 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE-NTESFTL--LIIPECNRY 20840
Query: 338 DTGRYTCLATNPSG 351
DTG++ NP+G
Sbjct: 20841 DTGKFVMTIENPAG 20854
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 1027 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 1086
+RL + G P P++ W+K L TDR + + + L+I T+ D+G Y ++
Sbjct: 25125 LRLFVTIKGRPEPEVKWEKAEGIL---TDRAQI-EVTSSFTMLVIDNVTRFDSGRYNLTL 25180
Query: 1087 KNEAGIVSCTARLDVYI 1103
+N +G S TA ++V +
Sbjct: 25181 ENNSG--SKTAFVNVRV 25195
Score = 33.9 bits (76), Expect = 0.88
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V GS + ++ ++G P P+V +G L T +L T+ + E+ D GR
Sbjct: 26488 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL-TINLKESVTADAGR 26546
Query: 342 YTCLATNPSGSDTTSAEVFI 361
Y A N SG TT A + I
Sbjct: 26547 YEITAANSSG--TTKAFINI 26564
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 777 PFFEMKLKHYKIFE---GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
P ++ L++ ++ + G V ++G P P I W+KD K++ + ++ D
Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA-LVCVENTTDLA 26928
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
L A L + G Y + N G S T R+ +
Sbjct: 26929 SILIKDADRL-NSGCYELKLRNAMGSASATIRVQI 26962
Score = 33.9 bits (76), Expect = 0.88
Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 6/110 (5%)
Query: 986 ATNRAGQNS-FSLELVVAAKEA-HKPPVFIEKLQNTGVAD--GYPVRLECRVLGVPPPQI 1041
A N AGQ + V AK+ P + ++ T V G V++ G PPP +
Sbjct: 27244 AVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTV 27303
Query: 1042 FWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
W+K+ ++L S R S+ + + L I T+ D G Y ++ +N G
Sbjct: 27304 TWRKDEKNL-GSDARYSIENTDSSSL-LTIPQVTRNDTGKYILTIENGVG 27351
Score = 33.9 bits (76), Expect = 0.88
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
+ G+ + ++ V+G P +V WF+ G EI+ + I + +L + +
Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST--------SLFVRDA 28021
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVV 538
+ G++T A+N GSA + ++ V
Sbjct: 28022 TRDHRGVYTVEAKNASGSAKAEIKVKV 28048
Score = 33.5 bits (75), Expect = 1.1
Identities = 42/157 (26%), Positives = 63/157 (40%), Gaps = 11/157 (7%)
Query: 209 NQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQ-DNQDLAVPHNRKSHPQPH--SAL 265
N P LS +E + E + G RH + N L N + PH SA
Sbjct: 8682 NYPEIKLSWYKGTEKLEPSDKFE--ISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAK 8739
Query: 266 HFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGD 325
P + + L+ + EG + C+ + P + WF G+ L + E
Sbjct: 8740 LTVIEPAWERHLQDVTLKEGQTCTMTCQFSV-PNVKSEWFRNGRILKPQGRHKTEVEH-K 8797
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+H L IA+ +D G+YTC + TSAE+ IE
Sbjct: 8798 VHKLTIADVRAEDQGQYTCKYEDLE----TSAELRIE 8830
Score = 33.5 bits (75), Expect = 1.1
Identities = 31/124 (25%), Positives = 49/124 (39%), Gaps = 6/124 (4%)
Query: 982 YTCIATNRAGQNSFS--LELVVAAKEAHKPPVFIEK--LQNTGVADGYPVRLECRVLGVP 1037
Y A NR G + S E + A P +F++ L V G + L V G P
Sbjct: 13659 YRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 13718
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 1097
P+I W K + L D+ ++ + I + + D G Y + A N G +
Sbjct: 13719 EPKITWTKADMIL--KQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVV 13776
Query: 1098 RLDV 1101
++V
Sbjct: 13777 EVNV 13780
Score = 33.5 bits (75), Expect = 1.1
Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 6/84 (7%)
Query: 914 LQAPGD-LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS---- 968
L GD + V+ G+ + V+GLP P + W + + + + +E S
Sbjct: 15401 LSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKT 15460
Query: 969 -LIIEPVTSRDAGIYTCIATNRAG 991
L I D G YT A+NR G
Sbjct: 15461 ELSIPKAVREDKGTYTVTASNRLG 15484
Score = 33.5 bits (75), Expect = 1.1
Identities = 17/73 (23%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G + R+ VSG P P ++W ++ + + ++ + + S++I+
Sbjct: 16534 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS---SMVIKNCQRSHQ 16590
Query: 980 GIYTCIATNRAGQ 992
G+Y+ +A N AG+
Sbjct: 16591 GVYSLLAKNEAGE 16603
Score = 33.5 bits (75), Expect = 1.1
Identities = 49/202 (24%), Positives = 82/202 (40%), Gaps = 21/202 (10%)
Query: 901 NEPIQERFFRPHFLQAPG-DLTV--------QEGKLCRMDCKVSGLPTPDLSWQLDGKPV 951
NEP+Q + L+AP DL V + G+ ++ G P P ++W+ D K +
Sbjct: 27257 NEPVQAK----DILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNL 27312
Query: 952 RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV 1011
D+ + + + L I VT D G Y N G+ S + + P
Sbjct: 27313 GSDARYS-IENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSS----TVSVKVLDTPA 27367
Query: 1012 FIEKLQNTGVADGYPVRL-ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
+KLQ V+ G L + ++ P I + E T T V H+ + L+
Sbjct: 27368 ACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI 27427
Query: 1071 IQGATKEDAGWYTVSAKNEAGI 1092
+++ ++ V A+NE GI
Sbjct: 27428 --DLSEKTPFFFRVLAENEIGI 27447
Score = 33.5 bits (75), Expect = 1.1
Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 8/137 (5%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELV--VAAKEAHKPPVFIEKLQNTG----VADG 1024
+ ++ D + +A N AG S E V ++ + PP + G + G
Sbjct: 29003 VTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAG 29062
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
+ L+ V G P P+I W K ++ L ++VS+ Q +I+ + D+G YT+
Sbjct: 29063 SDLVLDAAVGGKPEPKIIWTKGDKEL-DLCEKVSL-QYTGKRATAVIKFCDRSDSGKYTL 29120
Query: 1085 SAKNEAGIVSCTARLDV 1101
+ KN +G + + + V
Sbjct: 29121 TVKNASGTKAVSVMVKV 29137
Score = 33.1 bits (74), Expect = 1.5
Identities = 31/130 (23%), Positives = 53/130 (40%), Gaps = 18/130 (13%)
Query: 986 ATNRAGQN--SFSLELVVAAKEAHKPPVFIEKLQNTGVAD------GYPVRLECRVLGVP 1037
A N AG++ S + + A +P VFI+ G D G +R+ + G P
Sbjct: 15783 AVNEAGESEPSDTTGEIPATDIQEEPEVFID----IGAQDCLVCKAGSQIRIPAVIKGRP 15838
Query: 1038 PPQIFW------KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
P+ W KK + H + + ++I + G Y+++AKN+AG
Sbjct: 15839 TPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAG 15898
Query: 1092 IVSCTARLDV 1101
+ R+ V
Sbjct: 15899 QKTANCRVKV 15908
Score = 33.1 bits (74), Expect = 1.5
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 12/82 (14%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESL----THSTDRVSMHQDNHGYICLLIQGATKEDA 1079
G +R+ V G PPP + W +L T T +S ++I+ +
Sbjct: 16539 GGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSS--------MVIKNCQRSHQ 16590
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G Y++ AKNEAG T +DV
Sbjct: 16591 GVYSLLAKNEAGERKKTIIVDV 16612
Score = 33.1 bits (74), Expect = 1.5
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 284 EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTGRY 342
E S L+ + G P P V W +G++ T D ++ E ++T LI+ + + D G+Y
Sbjct: 19996 ENSNFRLKIPIKGKPAPSVSWK-KGEDPLAT-DTRVSVESSAVNTTLIVYDCQKSDAGKY 20053
Query: 343 TCLATNPSGSDTTSAEVFIEG 363
T N +G+ + + + G
Sbjct: 20054 TITLKNVAGTKEGTISIKVVG 20074
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
+V GQ + +E + G P + W + G ++ + + + ++ TL I E
Sbjct: 23240 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV--------TDSLDLTTLSIKE 23291
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLV 537
T +D G + + N G T++ ++V
Sbjct: 23292 THKDDGGQYGITVANVVGQKTASIEIV 23318
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
V G R+ G P P+I W +E TD+V + + Y L I + DAG
Sbjct: 24036 VRAGGSARIHIPFKGRPTPEITWSREEGEF---TDKVQI-EKGVNYTQLSIDNCDRNDAG 24091
Query: 1081 WYTVSAKNEAGIVSCTARLDV 1101
Y + +N +G S + V
Sbjct: 24092 KYILKLENSSGSKSAFVTVKV 24112
Score = 33.1 bits (74), Expect = 1.5
Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 296 GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTT 355
G P V W +G+ L T + + + +L I EA ++D G Y +N +GS T
Sbjct: 25420 GRPQATVNWRKDGQTLKETTRVNVS-SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 25478
Query: 356 SAEVFI 361
+ +
Sbjct: 25479 PITIIV 25484
Score = 32.7 bits (73), Expect = 2.0
Identities = 66/322 (20%), Positives = 121/322 (37%), Gaps = 62/322 (19%)
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
+A F K ++ +I EG F C ++ P + W +D K + D Y + D
Sbjct: 12550 LAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLE-SGDKYDVIADGKKRV 12607
Query: 835 SLHTTASTLDDDGNYTIM--AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 892
L +TL D G Y +M AA ++ +L +
Sbjct: 12608 -LVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVV---------------------- 12644
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
P++ D V+E + +C+V+ W + + +
Sbjct: 12645 ----------PLK-------------DTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIF 12680
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF 1012
DS+ ++++++ V++L I D Y TN G+N S ++ +E +
Sbjct: 12681 -DSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLR---I 12736
Query: 1013 IEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
+E L++ + V C+V L V + W K E + +RVS D + ++ L
Sbjct: 12737 VEPLKDIETMEKKSVTFWCKVNRLNV---TLKWTKNGEEVPFD-NRVSYRVDKYKHM-LT 12791
Query: 1071 IQGATKEDAGWYTVSAKNEAGI 1092
I+ D G Y V+A + +
Sbjct: 12792 IKDCGFPDEGEYIVTAGQDKSV 12813
Score = 32.7 bits (73), Expect = 2.0
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD-IQIHCE---GGDLHT-LIIAEAF 335
+V G V++ VTG P P++ W + D +QI E + T L I +A
Sbjct: 15409 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 15468
Query: 336 EDDTGRYTCLATNPSGS 352
+D G YT A+N GS
Sbjct: 15469 REDKGTYTVTASNRLGS 15485
Score = 32.7 bits (73), Expect = 2.0
Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ ++D + G P P + W + G ++A + + SL ++ D+
Sbjct: 22553 IVVHAGESFKVDADIYGKPIPTIQW-IKGDQELSNTARLEIKSTDFATSLSVKDAVRVDS 22611
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y A N AG+ S ++ + V
Sbjct: 22612 GNYILKAKNVAGERSVTVNVKV 22633
Score = 32.7 bits (73), Expect = 2.0
Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G+ V LE G P P I W K+ L S I L I+ A KE G YT
Sbjct: 27578 GHNVHLELPYKGKPKPSISWLKDGLPLKES--EFVRFSKTENKITLSIKNAKKEHGGKYT 27635
Query: 1084 VSAKN 1088
V N
Sbjct: 27636 VILDN 27640
Score = 32.3 bits (72), Expect = 2.5
Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 271 PRFIQKLRSQEVA---EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
PR + ++ ++V G + + + G P P + W +G E+ +I D H
Sbjct: 25787 PRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI--ISTDNH 25844
Query: 328 TLI-IAEAFEDDTGRYTCLATNPSGS 352
TL+ + + DTG+Y N +G+
Sbjct: 25845 TLLTVKDCIRRDTGQYVLTLKNVAGT 25870
Score = 32.3 bits (72), Expect = 2.5
Identities = 22/105 (20%), Positives = 47/105 (44%), Gaps = 11/105 (10%)
Query: 437 AYFPPVFTKELQNTAVAE---GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKK 493
+Y PV L+ T V + G V L + G P ++W++ E+Q + +
Sbjct: 26866 SYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCV---- 26921
Query: 494 PRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ +++I + ++G + RN GSA++T ++ +
Sbjct: 26922 ----ENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 26962
Score = 32.3 bits (72), Expect = 2.5
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 918 GDL-TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTS 976
GDL T++ G +D V G P P + W K + D K+ ++ G + +
Sbjct: 29054 GDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCD 29111
Query: 977 R-DAGIYTCIATNRAGQNSFSLELVV 1001
R D+G YT N +G + S+ + V
Sbjct: 29112 RSDSGKYTLTVKNASGTKAVSVMVKV 29137
Score = 32.0 bits (71), Expect = 3.3
Identities = 49/236 (20%), Positives = 90/236 (38%), Gaps = 26/236 (11%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+ I+ LR E V E ++ + V W + KE+ + +I G ++ L +
Sbjct: 2534 KIIRGLRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHG-KIYKLTV 2591
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGAS-------STDSDSESLAFKSRAGAMP 384
+DD G+YT A G + TS ++ + G + T ++S+ F+ A P
Sbjct: 2592 LNMMKDDEGKYTFYA----GENMTSGKLTVAGGAISKPLTDQTVAESQEAVFECEV-ANP 2646
Query: 385 QAQ----KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFP 440
++ + + LT S G +I + ++ Y + + T+
Sbjct: 2647 DSKGEWLRDGKHLPLTNNIRSESDGHKRRLI----IAATKLDDIGEYTYKVATSKTSAKL 2702
Query: 441 PV----FTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
V K L+N V E Q V + VQW + G ++ + + I K
Sbjct: 2703 KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVK 2758
Score = 32.0 bits (71), Expect = 3.3
Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G + L + G PTP V+W GK D I +L++ D+G+
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKW---GKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGK 23010
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SG+ + V
Sbjct: 23011 YTLTLENSSGTKSAFVTV 23028
Score = 32.0 bits (71), Expect = 3.3
Identities = 30/118 (25%), Positives = 44/118 (37%), Gaps = 6/118 (5%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
+P L P + + V G + G PTP + W E E T +QI
Sbjct: 24014 KPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQI 24071
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFK 377
+G + L I +D G+Y N SGS + V + T ++LA K
Sbjct: 24072 E-KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV---LDTPGPPQNLAVK 24125
Score = 32.0 bits (71), Expect = 3.3
Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P ++ K ++ V G LE + G
Sbjct: 24675 FRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGK 24734
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 1094
P P + W K+ + L + R+ + + L+++ + D G Y + N G S
Sbjct: 24735 PIPDVVWSKDGKELEETAARMEI-KSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 24791
Score = 31.6 bits (70), Expect = 4.3
Identities = 20/88 (22%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
++ G+ + +E V G P + W + G ++ + + E L I E
Sbjct: 24322 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV--------EETATSTVLHIKE 24373
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVV 538
+D G +T +A N G+AT ++V
Sbjct: 24374 GNKDDFGKYTVTATNSAGTATENLSVIV 24401
Score = 31.6 bits (70), Expect = 4.3
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
G V+LE G P P + W +G L + ++ + TL I A ++ G+YT
Sbjct: 27578 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAKKEHGGKYTV 27636
Query: 345 LATN 348
+ N
Sbjct: 27637 ILDN 27640
Score = 31.6 bits (70), Expect = 4.3
Identities = 22/80 (27%), Positives = 31/80 (38%), Gaps = 3/80 (3%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V+ G R+ G PTP W KP S + + +L +E DAG
Sbjct: 28369 VRAGASIRLFIAYQGRPTPTAVWS---KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGK 28425
Query: 982 YTCIATNRAGQNSFSLELVV 1001
YT N +G S + + V
Sbjct: 28426 YTLTVENNSGSKSITFTVKV 28445
Score = 31.6 bits (70), Expect = 4.3
Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G+ + L G PTP W L DI TL + +D G+
Sbjct: 28369 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT---DSFSTLTVENCNRNDAGK 28425
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SGS + + V
Sbjct: 28426 YTLTVENNSGSKSITFTV 28443
Score = 31.6 bits (70), Expect = 4.3
Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 9/112 (8%)
Query: 770 PVENGMAPFFEMK---LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTI 826
PVE P E+ K I G + V+G P P I W K G ++ ++ I
Sbjct: 29437 PVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA----I 29492
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
+ L D G YTI A N G+ S T ++V+ + G P
Sbjct: 29493 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSAT--VLVKVYDTPGPCP 29542
Score = 31.6 bits (70), Expect = 4.3
Identities = 21/94 (22%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 446 ELQNTAVAEGQVVVLECRVRGAPP-LQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
++ + EG V C++ QV W+ ++++S + I + + +
Sbjct: 31573 QIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE--------DGVA 31624
Query: 505 TLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L + + D G + C NDYG +S A+L V
Sbjct: 31625 ILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 31658
Score = 31.2 bits (69), Expect = 5.7
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
A FI K ++ E+ EG + C ++ P V+W + K L + + + G L
Sbjct: 12551 AAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIAD-GKKRVL 12608
Query: 330 IIAEAFEDDTGRYTCL 345
++ +A D G Y +
Sbjct: 12609 VVKDATLQDMGTYVVM 12624
Score = 31.2 bits (69), Expect = 5.7
Identities = 18/69 (26%), Positives = 29/69 (42%), Gaps = 5/69 (7%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P+T PK + WFK+ + +S K+ T ++ S + D G Y
Sbjct: 13014 GKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQ-----TSFRILEAKKGDKGRYK 13068
Query: 851 IMAANPQGR 859
I+ N G+
Sbjct: 13069 IVLQNKHGK 13077
Score = 31.2 bits (69), Expect = 5.7
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G+ VLE +RG P V W + G E++++ + + +ST + TLV+ +
Sbjct: 24719 VHAGETFVLEADIRGKPIPDVVWSKDGKELEET----AARMEIKSTIQK---TTLVVKDC 24771
Query: 512 FPEDAGIFTCSARNDYGS 529
D G + N G+
Sbjct: 24772 IRTDGGQYILKLSNVGGT 24789
Score = 31.2 bits (69), Expect = 5.7
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G+ + L V+G P P + W +G +L + I E L LI+ + D G+
Sbjct: 29458 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDT-TESYSL--LIVDKVNRYDAGK 29514
Query: 342 YTCLATNPSGSDTTSAEV 359
YT A N SG + + V
Sbjct: 29515 YTIEAENQSGKKSATVLV 29532
Score = 31.2 bits (69), Expect = 5.7
Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 7/114 (6%)
Query: 254 NRKSHPQPHSALHFPAAPRFIQKLRSQEV---AEGSRVYLECRVTGNPTPRVRWFCEGKE 310
N + S L A P+F +E A GS + L G P P + WF K
Sbjct: 30609 NEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKL 30668
Query: 311 LHNTPDIQIHCEGGDLHTLIIAEAFEDDT--GRYTCLATNPSGSDTTSAEVFIE 362
L N+ +I I E + +T ++ + + T G+Y +N G+ +V I+
Sbjct: 30669 LQNSENITI--ENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 30720
Score = 30.8 bits (68), Expect = 7.4
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Query: 433 GTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
G + Y V T L++ V EG VLEC+V V+W+ +I+ PD R+ Q
Sbjct: 2438 GRVSVYSVDVITP-LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIK--PDDRV-QA 2493
Query: 493 KPRSTAEPEEICTLVIAETFPEDAG 517
+ T + LVI T D G
Sbjct: 2494 IVKGTKQ-----RLVINRTHASDEG 2513
Score = 30.8 bits (68), Expect = 7.4
Identities = 24/95 (25%), Positives = 34/95 (35%), Gaps = 10/95 (10%)
Query: 445 KELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
K ++ V G V +RG P +W GSEI+ + T E +
Sbjct: 17515 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHY---------TVETDNFS 17565
Query: 505 T-LVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ L I D G + + N GS T L V
Sbjct: 17566 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 30.8 bits (68), Expect = 7.4
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 8/76 (10%)
Query: 455 GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPE 514
G+ LE V G PP ++W + G E++ + I + LV ++
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEI--------KIADFSTNLVNKDSTRR 21527
Query: 515 DAGIFTCSARNDYGSA 530
D+G +T +A N G A
Sbjct: 21528 DSGAYTLTATNPGGFA 21543
Score = 30.8 bits (68), Expect = 7.4
Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 9/98 (9%)
Query: 1003 AKEAHKPPVF---IEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSM 1059
AKE + P+F E + V G + G P P + W K + L R
Sbjct: 26177 AKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-----RTRA 26231
Query: 1060 HQDN-HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
+ D L I+ A + D+G YT++ +N S T
Sbjct: 26232 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT 26269
Score = 30.4 bits (67), Expect = 9.7
Identities = 20/94 (21%), Positives = 40/94 (42%), Gaps = 8/94 (8%)
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
+ + G+ + +E V G P +W + E+ S + + S L+
Sbjct: 18906 EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI--------LI 18957
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA 541
I + +D+G ++ +A N G+ T ++VV A
Sbjct: 18958 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 18991
Score = 30.4 bits (67), Expect = 9.7
Identities = 26/119 (21%), Positives = 50/119 (42%), Gaps = 10/119 (8%)
Query: 749 EYRLERSPVDESG--DEVQYGDVP-VENGMAPFFEMKLKHYK---IFEGMPVTFTCRVAG 802
+Y S ++++G + DV VE MAP FE+ + + + G+ + + G
Sbjct: 20743 KYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKG 20802
Query: 803 NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 861
P P++ W KD + +++ + + L D G + + NP G+ S
Sbjct: 20803 RPAPEVTWTKDNINLKNRAN----IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKS 20857
Score = 30.4 bits (67), Expect = 9.7
Identities = 17/60 (28%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 802 GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 861
G PKP I W KDG + K + + +L + + G YT++ N RI+
Sbjct: 27589 GKPKPSISWLKDGLPL--KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIA 27646
Score = 30.4 bits (67), Expect = 9.7
Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P T ++G P PK+ W + ++ ++D +I D T +L S D G Y
Sbjct: 28662 GSPFTIDVPISGRPAPKVTWKLEEMRLK-ETDRVSITTTKDRT-TLTVKDSMRGDSGRYF 28719
Query: 851 IMAANPQG 858
+ N G
Sbjct: 28720 LTLENTAG 28727
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 270 bits (691), Expect = 4e-72
Identities = 197/724 (27%), Positives = 328/724 (45%), Gaps = 76/724 (10%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP L+N V EG+ V LEC + G P V W+R+ +I+ S DF+I +
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG----- 950
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHF 559
I L+I E F ED+G FTCSA N+ G+ +++ L V + ++ E
Sbjct: 951 ---IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEE 1007
Query: 560 QHFPPPPPILETSSL----ELASKKPSEIQQVNNP------ELGLSRAALQMQFNAAER- 608
+ F ++ T + + +P+ + P E G Q+ N
Sbjct: 1008 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1067
Query: 609 --ETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTAR 666
+ +GV + G ++ + + ++ + ++ + K G ++
Sbjct: 1068 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLE 1127
Query: 667 IASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTY---------EERMARRLLGADS 717
A E + ++ ++ + +E + P Y E+ + R+ + D+
Sbjct: 1128 EADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187
Query: 718 ATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDE----SGDEVQYGDVPVEN 773
V E +QE+ +SS E+RLI EIEYR+ ++ ++E G+E D+
Sbjct: 1188 VVVRTYVE------DQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESE 1241
Query: 774 GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
+ F+ ++K+Y+I EGM VTF C+++G P PKI W+KDGK+I + Y + DG
Sbjct: 1242 AVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGR 1300
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR----------------S 877
SL +D+G YT A+N +G C+G+L V+ G S
Sbjct: 1301 ASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLS 1360
Query: 878 PRSPSGHPHVRRPRSRS-----------------RDSGDENEPIQERFFRPHFLQAPGDL 920
PRS S P P S R + +E ER ++P F+ P
Sbjct: 1361 PRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSF 1420
Query: 921 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 980
EG+ R D KV G P P+ W DG+ + D HK++++E+G SLII P T D+G
Sbjct: 1421 KCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSG 1480
Query: 981 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ 1040
+T +A NRAG++S S+ L V A E P+F+EKL+N + +G + ++ R G P P
Sbjct: 1481 EWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPD 1540
Query: 1041 IFWKKENESLT-HSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
I W K ++ + H ++ + + G L I +D+ WYT +A N+AG + ++
Sbjct: 1541 IVWLKNSDIIVPHKYPKIRI-EGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKV 1599
Query: 1100 DVYI 1103
+V +
Sbjct: 1600 NVEV 1603
Score = 136 bits (342), Expect = 1e-31
Identities = 200/928 (21%), Positives = 336/928 (36%), Gaps = 179/928 (19%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F + ++ +V E R EC V+ P V+W + +EL T I+I E +H L+I
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKY-VHRLLIP 3071
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTS 392
D G+YT +A G + ++A++F+EG + +S + +K+
Sbjct: 3072 STRMSDAGKYTVVA----GGNVSTAKLFVEG--------RDVRIRSIKKEVQVIEKQRAV 3119
Query: 393 VSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSP----------------------TSYLCR 430
V + I+ ++ VQ+ H T R
Sbjct: 3120 VEFEVNEDDVDAHWYKDGIE-INFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR 3178
Query: 431 PDGTTTAYF----PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
+ T Y PP +ELQ V G+ + G P ++ W+++ +
Sbjct: 3179 NRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFK 3238
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENC 546
+ L + +E TL++ E FPEDA ++TC A+NDYG AT++A L V +
Sbjct: 3239 CKFLH-------DGQEY-TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSP 3290
Query: 547 SYESMGESNNDHFQHFPPPPPILETSSLELASKK--PSEIQ-QVNNPELGLS-------- 595
Q P PP + T + + + P+ Q +V+ +L +S
Sbjct: 3291 D------------QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKI 3338
Query: 596 -----------RAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTK 644
Q++ A E G + N + + +N SL A+
Sbjct: 3339 KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQAL------ 3392
Query: 645 EPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTY 704
+ S + + Q D+ E K+ KE G Y
Sbjct: 3393 --------------DRQSSGKDVRESAKSQAVADSSFTKEESKISQKEIKSFQGSS-YEY 3437
Query: 705 EERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEV 764
E ++ + + T ++Q+ + C +S+I E S E E
Sbjct: 3438 EVQVFESVSQSSIHTAASVQDTQ-----------LCHTASLSQIAESTELSK--ECAKE- 3483
Query: 765 QYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHY 824
G AP + L+ + G F C + + + W +G +I
Sbjct: 3484 -------STGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESE--- 3533
Query: 825 TIQRDLDGTCSLHTTAST-LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG 883
+++ +G T + L D G Y+ + N G + + L V+ + R
Sbjct: 3534 RLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQE 3593
Query: 884 HPHVRRPRSRSRDSGDEN---------------------EPIQERFFR-------PHFLQ 915
+ S S S +E P+ F P F++
Sbjct: 3594 IEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIK 3653
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
+ + G + + V G+P P + W +G + P + +K V + HSLII
Sbjct: 3654 EVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKF-VFDGDDHSLIILFTK 3712
Query: 976 SRDAGIYTCIATNRAGQNSFSLELVVAAK-EAHK-------------------PPVFIEK 1015
D G YTC+A+N G+ S L + +K E HK PP F+++
Sbjct: 3713 LEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKE 3772
Query: 1016 LQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGAT 1075
L+ A G P E V+G P P + W KEN+ L S +H N G ++
Sbjct: 3773 LKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN-GSGTFIVNDPQ 3831
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
+ED+G Y A+N G +C A L V +
Sbjct: 3832 REDSGLYICKAENMLGESTCAAELLVLL 3859
Score = 119 bits (299), Expect = 1e-26
Identities = 196/916 (21%), Positives = 336/916 (36%), Gaps = 181/916 (19%)
Query: 213 ALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFP--AA 270
A+ S +SP E + + VKSP + + AV H P A
Sbjct: 26354 AVTSPPRVKSP-EPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAP 26412
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P+ Q L+++ E +++ + V W+ +GK+L Q H + L
Sbjct: 26413 PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 26472
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
I E D G Y C + G+ T+ + + S S+ ++ +KT
Sbjct: 26473 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKV------SKISETKKSDQKT 26526
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT 450
T ++T + PK +P+S PV LQ+T
Sbjct: 26527 TESTVT-RKTEPKAP------EPISSK-----------------------PVIVTGLQDT 26556
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
V+ V + G P W + G I +++ + K E I +
Sbjct: 26557 TVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE--------IHK 26608
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPPILE 570
T D+G++TC+ +N GS +S+ +L + + I +
Sbjct: 26609 TDTSDSGLYTCTVKNSAGSVSSSCKLTIKA---------------------------IKD 26641
Query: 571 TSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSN 630
T + +++++K SEI P+ +A +Q + S
Sbjct: 26642 TEAQKVSTQKTSEI----TPQ---KKAVVQEEI-------------------------SQ 26669
Query: 631 KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGT------KDAVIQDL 684
K+L + + +S K ++ KL ++AS ++ EE++ + K V +++
Sbjct: 26670 KALRSEEIKMSEAK------SQEKLALKEEAS---KVLISEEVKKSAATSLEKSIVHEEI 26720
Query: 685 ERKLRFKEDLLNNG-------QPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYK- 736
+ + E++ + Q + +R+ + A + V + E T ++EY+
Sbjct: 26721 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRY 26780
Query: 737 -VSSCEQRL-ISEIEYRLER-----SPVDESGDEVQYG-DVPVENGMAPFFEMKLKHYKI 788
VS +Q L I + +R E S E + QY + E AP F + + I
Sbjct: 26781 GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNI 26840
Query: 789 FEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGN 848
EG V FTC ++G P P+I WFK+ IS S + +I R + SL +++ D G
Sbjct: 26841 NEGQNVLFTCEISGEPSPEIEWFKNNLPIS-ISSNVSISRSRN-VYSLEIRNASVSDSGK 26898
Query: 849 YTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR--SRDSGDENEPIQE 906
YTI A N +G+ S T LMV P V P R SGD +
Sbjct: 26899 YTIKAKNFRGQCSATASLMVL---------------PLVEEPSREVVLRTSGDTS----- 26938
Query: 907 RFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGV 966
LQ + + + S + S + K SA M + +
Sbjct: 26939 -------LQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMK-FASMSAQSM----SSM 26986
Query: 967 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYP 1026
+E +S GI + Q S ++ A PP + + +G
Sbjct: 26987 QESFVEMSSSSFMGI------SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKV 27040
Query: 1027 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDN-HGYICLLIQGATKEDAGWYTVS 1085
+ + C G P P++ W + HS ++ H +N L+I K+D G YT+S
Sbjct: 27041 LTVACAFTGEPTPEVTWSCGGRKI-HSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLS 27099
Query: 1086 AKNEAGIVSCTARLDV 1101
NE G S T + +
Sbjct: 27100 LGNEFGSDSATVNIHI 27115
Score = 118 bits (295), Expect = 4e-26
Identities = 195/931 (20%), Positives = 327/931 (35%), Gaps = 162/931 (17%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
QP + H APR ++RS V G V PT V+W+ G EL + I
Sbjct: 26061 QPFTLDH---APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHY 26117
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSR 379
G L TL I + DD+G Y + TN G + A + + G T S+ +
Sbjct: 26118 TNTSGVL-TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVP 26176
Query: 380 AGAMPQAQ----------KKTTSVSLTIGSSSPKTGVT-----------TAVIQPLSVPV 418
P+ KKT+ + + K+ +T +A + S +
Sbjct: 26177 RSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 26236
Query: 419 QQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQG 478
++ R TT A + TK T V EG+ C G P V W R+G
Sbjct: 26237 EEKSLEEKSTTRKIKTTLA--ARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKG 26293
Query: 479 SEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ S ++ K +ST E I+ D G ++ N G + L +
Sbjct: 26294 QVLSTSARHQVTTTKYKSTFE--------ISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26345
Query: 539 TSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQ---QVNNPELGLS 595
A + S PP + S E K P ++ +V +PE
Sbjct: 26346 QKARVTEKAVTS--------------PPRV---KSPEPRVKSPEAVKSPKRVKSPEPSHP 26388
Query: 596 RAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKL 655
+A V P+ K PT V P PP + K
Sbjct: 26389 KA---------------VSPTE------------TKPTPTEKVQHLPVSAPPKITQFLKA 26421
Query: 656 GFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMAR----- 710
K+ ++ + ++ + +D +KL+ + TYE ++
Sbjct: 26422 EASKEIAKLTCVVESSVLRAKEVTWYKD-GKKLKENGHFQFHYSADGTYELKINNLTESD 26480
Query: 711 ------RLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEV 764
+ G + N+Q + + KVS ISE + + ++ + +
Sbjct: 26481 QGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSK-----ISETK-KSDQKTTESTVTRK 26534
Query: 765 QYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHY 824
P P L+ + F + G P+P W KDGK I+ + Y
Sbjct: 26535 TEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT-QGGKY 26593
Query: 825 TIQRDLDG----------------TCSLHTTASTLDDDGNYTIMAAN------------- 855
+ D G TC++ +A ++ TI A
Sbjct: 26594 KLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTS 26653
Query: 856 ---PQGRISCTGRL-----------MVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDEN 901
PQ + + M +A +Q + + + + +S + E
Sbjct: 26654 EITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEK 26713
Query: 902 EPIQERF---------FRPH--FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
+ E R H +++ EG+ + ++G D+ W L+G
Sbjct: 26714 SIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVE 26771
Query: 951 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP 1010
+ ++ V + +L I+ + RD GI TCI+ + G +L ++ KE P
Sbjct: 26772 LTNSEEYRYGVSGSD-QTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS-KELSDAP 26829
Query: 1011 VFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
FI + ++ + +G V C + G P P+I W K N ++ S++ VS+ + + Y L
Sbjct: 26830 AFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN-VSISRSRNVY-SLE 26887
Query: 1071 IQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
I+ A+ D+G YT+ AKN G S TA L V
Sbjct: 26888 IRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918
Score = 109 bits (273), Expect = 1e-23
Identities = 88/322 (27%), Positives = 139/322 (43%), Gaps = 27/322 (8%)
Query: 790 EGMPVTFTCRVAG-NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGN 848
EG V + C++ + ++ W+ +Q+ S+ Y I + DG L+ T DDG
Sbjct: 25276 EGGHVKYVCKIENYDQSTQVTWYFGVRQLE-NSEKYEITYE-DGVAILYVKDITKLDDGT 25333
Query: 849 YTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERF 908
Y N G S L V+ V + + RR + + D ++
Sbjct: 25334 YRCKVVNDYGEDSSYAELFVKGVRE--------VYDYYCRRTMKKIKRRTDTMRLLERP- 25384
Query: 909 FRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN--GV 966
P F + T G+ R ++ P P ++W G+ ++P K E+ G+
Sbjct: 25385 --PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGL 25442
Query: 967 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP-------VFIEKLQNT 1019
+ L I VT+ D YT +A N+ G++S +L V H PP +F L N
Sbjct: 25443 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTL---HPPPTDSTLRPMFKRLLANA 25499
Query: 1020 GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 1079
+G V E RV G+PPP + W+K+ + L+ + +H + Y L I+ ED
Sbjct: 25500 ECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH-EGLDYYALHIRDTLPEDT 25558
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G+Y V+A N AG SC A L V
Sbjct: 25559 GYYRVTATNTAGSTSCQAHLQV 25580
Score = 103 bits (258), Expect = 7e-22
Identities = 101/414 (24%), Positives = 174/414 (42%), Gaps = 61/414 (14%)
Query: 154 PKTPHQRKGGPQSQLCDKAANLIEELTSIFKAAKPRNRSPNGESSSPDSGYLSPKNQPSA 213
PKT H G ++ + A +++ S +A+ +S + P + + +P+
Sbjct: 778 PKTEH----GYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRV--RAEPTP 831
Query: 214 LLSASASQSPMEDQGEMEREVKSP---GARHCYQDNQDLAVPHNRKSHPQPHSALHFPAA 270
L + +P + E EVK + V H R++ + + P
Sbjct: 832 LPQFPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVE 891
Query: 271 -----PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGD 325
P + L++ V EG V LEC ++G P+P V W+ E ++ ++ D QI + G
Sbjct: 892 IPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG- 950
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ 385
+ L+I EAF +D+GR+TC A N +G+ +TS + ++ +
Sbjct: 951 IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ-------------------VSEE 991
Query: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF--PPVF 443
+K+TT+V+ + + + V+ + S T P YF PV
Sbjct: 992 FEKETTAVTEKFTTEEKRFVESRDVVMTDT-------SLTEEQAGPGEPAAPYFITKPVV 1044
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
K + EG VV C+V G P V W + G + +++ K T E
Sbjct: 1045 QK------LVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNK--QTGE---- 1092
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNND 557
C LVI+ TF +DAG +T RN +G +++A L+ E YE + +S +
Sbjct: 1093 CKLVISMTFADDAGEYTIVVRNKHGETSASASLL------EEADYELLMKSQQE 1140
Score = 101 bits (252), Expect = 3e-21
Identities = 65/191 (34%), Positives = 102/191 (53%), Gaps = 7/191 (3%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR-ENGVHSL 969
P F Q + V EG + +SG P P++SW DG+ + + + + +G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
I VT ++G Y+ ATN +GQ + + EL+V A+ A PP F+++LQ+ V G VRL
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA--PPNFVQRLQSMTVRQGSQVRL 123
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTD-RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
+ RV G+P P + + ++ + S D ++S D + LLI A ED+G Y+V+A N
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS---LLIAEAYPEDSGTYSVNATN 180
Query: 1089 EAGIVSCTARL 1099
G + TA L
Sbjct: 181 SVGRATSTAEL 191
Score = 95.9 bits (237), Expect = 2e-19
Identities = 95/393 (24%), Positives = 151/393 (38%), Gaps = 92/393 (23%)
Query: 759 ESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQIS 818
E DE Q +E P F +K +K EG F +V G P P+ +WF DG+QI
Sbjct: 1398 EETDESQ-----LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV 1452
Query: 819 PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
H + ++ DGT SL +T D G +T++A N GR S + L V+AV
Sbjct: 1453 NDYTHKVVIKE-DGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV------- 1504
Query: 879 RSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP 938
E +P F++ ++ ++EG M + +G P
Sbjct: 1505 ---------------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1537
Query: 939 TPDLSWQLDGKPVRPDSAHKMLVR-ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSL 997
PD+ W + + P K+ + G +L I+ S+D+ YT A N+AG+++
Sbjct: 1538 NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597
Query: 998 ELVVAA-----------------------------------------------KEAHKPP 1010
++ V KE + P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657
Query: 1011 VFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
F +KL + + P ECR+ +G P + W + + L + +R+ M + GY
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPL-EAANRLRMINE-FGYCS 1715
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
L A D+G T A N+ G +A L V
Sbjct: 1716 LDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1748
Score = 94.4 bits (233), Expect = 5e-19
Identities = 137/627 (21%), Positives = 240/627 (38%), Gaps = 97/627 (15%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P I L+ +EG +CRV+G +V W+ + K++ + ++ + D + L
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRM-TQFEDTYQLE 3356
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE----GASSTDSDSESLAFKSRAGAMPQA 386
IAEA+ +D G YT +A+N G +++A + +E S+ D A KS+A A
Sbjct: 3357 IAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRESA-KSQAVADSSF 3415
Query: 387 QKKTTSVS----------------LTIGSSSPKTGVTTAVIQPL----SVPVQQVHSPTS 426
K+ + +S S S + T A +Q + + Q+ T
Sbjct: 3416 TKEESKISQKEIKSFQGSSYEYEVQVFESVSQSSIHTAASVQDTQLCHTASLSQIAESTE 3475
Query: 427 YLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
+T P +F LQ+ V G C ++ + V W +G++I++S
Sbjct: 3476 LSKECAKESTGEAPKIFL-HLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEES-- 3532
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENC 546
L++ + IC + + D G+++C ND G T++A L V A E+
Sbjct: 3533 -ERLKQSQNGNIQFLTICNVQLV-----DQGLYSCIVHNDCGERTTSAVLSVEGA-PESI 3585
Query: 547 SYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAA 606
+E + + + F E L A + S+I + EL +F++
Sbjct: 3586 LHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINE--TLELLSESPVYPTKFDSE 3643
Query: 607 ERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTAR 666
+ T + I +N++ S+ A L+ +G PK
Sbjct: 3644 KEGTGPI--------FIKEVSNADISMGDVAT-----------LSVTVIGIPK------- 3677
Query: 667 IASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEP 726
+IQ + V+ +F D G D + + +
Sbjct: 3678 ----PKIQWFFNGVLLTPSADYKFVFD--------------------GDDHSLIILFTKL 3713
Query: 727 EEE-----TANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEM 781
E+E A+ +Y + C L +I + E E+ V + P F
Sbjct: 3714 EDEGEYTCMASNDYGKTICSAYL--KINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLK 3771
Query: 782 KLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAS 841
+LK + +G+P F V G P P + WFK+ KQ+ S +YTI + +G+ +
Sbjct: 3772 ELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLC-TSVYYTIIHNPNGSGTFIVNDP 3830
Query: 842 TLDDDGNYTIMAANPQGRISCTGRLMV 868
+D G Y A N G +C L+V
Sbjct: 3831 QREDSGLYICKAENMLGESTCAAELLV 3857
Score = 93.2 bits (230), Expect = 1e-18
Identities = 68/261 (26%), Positives = 116/261 (44%), Gaps = 43/261 (16%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F L+ + EG TF ++G P P++ WF+DG+ IS + DG
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
L A T + G Y++ A N G+ + T L+V+A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------------------------- 99
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
E P P+F+Q +TV++G R+ +V+G+PTP + + DG ++ S
Sbjct: 100 ----ETAP-------PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQ-SS 147
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---AHKPPVF 1012
+ +E ++SL+I D+G Y+ ATN G+ + + EL+V +E A K
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 1013 IEKLQNTGVADGYPVRLECRV 1033
+ Q +++ R+E ++
Sbjct: 208 VSTAQ---ISESRQTRIEKKI 225
Score = 89.0 bits (219), Expect = 2e-17
Identities = 44/95 (46%), Positives = 69/95 (72%), Gaps = 1/95 (1%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A P F+Q+L+S V +GS+V L+ RVTG PTP V+++ +G E+ ++ D QI E GDL++
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQE-GDLYS 160
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
L+IAEA+ +D+G Y+ ATN G T++AE+ ++G
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195
Score = 88.6 bits (218), Expect = 3e-17
Identities = 76/301 (25%), Positives = 132/301 (43%), Gaps = 28/301 (9%)
Query: 714 GADSATVFNIQEPEEETANQEYKVS--SCEQRLISEIEYRLERSPVDESGDEVQYGDV-- 769
GA + + E E E +E+ S S E+ + E +L S ++E+ + + V
Sbjct: 3580 GAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQL--SKINETLELLSESPVYP 3637
Query: 770 ----PVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYT 825
+ G P F ++ + I G T + V G PKPKI WF +G ++P +D+
Sbjct: 3638 TKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKF 3697
Query: 826 IQRDLDGTC-SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGH 884
+ DG SL + L+D+G YT MA+N G+ C+ L + N +G GH
Sbjct: 3698 V---FDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI---NSKGE------GH 3745
Query: 885 PHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSW 944
+ ++ P PHFL+ + +G + V G P P ++W
Sbjct: 3746 KDTETESAVAKSLEKLGGPCP-----PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTW 3800
Query: 945 QLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
+ K + + ++ NG + I+ D+G+Y C A N G+++ + EL+V +
Sbjct: 3801 FKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLE 3860
Query: 1005 E 1005
+
Sbjct: 3861 D 3861
Score = 88.6 bits (218), Expect = 3e-17
Identities = 77/323 (23%), Positives = 128/323 (39%), Gaps = 63/323 (19%)
Query: 246 NQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWF 305
N+ L + +P + P FI+++ + +++ G L V G P P+++WF
Sbjct: 3624 NETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWF 3683
Query: 306 CEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI--EG 363
G L + D + +G D H+LII +D G YTC+A+N G SA + I +G
Sbjct: 3684 FNGVLLTPSADYKFVFDGDD-HSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG 3742
Query: 364 ASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHS 423
D+++ES KS ++ L P
Sbjct: 3743 EGHKDTETESAVAKS--------------------------------LEKLGGP------ 3764
Query: 424 PTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQD 483
C P F KEL+ A+G + E V G P V WF++ ++
Sbjct: 3765 -----CPPH----------FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCT 3809
Query: 484 SPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT 543
S + I+ P T ++ + ED+G++ C A N G +T A+L+V +T
Sbjct: 3810 SVYYTIIH-------NPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDT 3862
Query: 544 ENCSYESMGESNNDHFQHFPPPP 566
+ +S + + FP P
Sbjct: 3863 DMTDTPCKAKSTPEAPEDFPQTP 3885
Score = 88.6 bits (218), Expect = 3e-17
Identities = 63/227 (27%), Positives = 93/227 (40%), Gaps = 33/227 (14%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISP--KSDHYTIQRDLDGTC 834
P F + L + + G V F + +P+P + W+K G++I P YT + D G
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESD-KGLY 25443
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 894
L + T DDD YT++A N G SC +L V HP
Sbjct: 25444 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTL-------------HP--------- 25481
Query: 895 RDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
P + RP F + + QEG+ + +VSG+P P L W+ DG+P+
Sbjct: 25482 --------PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLG 25533
Query: 955 SAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+++ ++L I D G Y ATN AG S L V
Sbjct: 25534 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25580
Score = 87.4 bits (215), Expect = 7e-17
Identities = 70/300 (23%), Positives = 129/300 (43%), Gaps = 39/300 (13%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP FI + RSQ + EG V C ++G P+P + WF + + ++ I ++++L
Sbjct: 26828 APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSI-SRSRNVYSL 26886
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI---------EGASSTDSD-SESLAFKSR 379
I A D+G+YT A N G + +A + + E T D S +F S+
Sbjct: 26887 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQ 26946
Query: 380 AGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVP-------------------VQQ 420
+ M ++++ + S + S+S T + A + S+ + Q
Sbjct: 26947 SVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQ 27006
Query: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
+ S TS + + PP + ++ EG+V+ + C G P +V W G +
Sbjct: 27007 LESSTSKMLK---AGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRK 27063
Query: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
I R +++ TL+I + +D G++T S N++GS ++T + + S
Sbjct: 27064 IHSQEQGRF------HIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27117
Score = 85.1 bits (209), Expect = 3e-16
Identities = 73/277 (26%), Positives = 119/277 (42%), Gaps = 30/277 (10%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP+ L+ V G C + + V W EG ++ + ++ + G++ L
Sbjct: 3488 APKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLK-QSQNGNIQFL 3546
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKK 389
I D G Y+C+ N G TTSA + +EGA ES+ + + K+
Sbjct: 3547 TICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAP------ESILHERIEQEIEMEMKE 3600
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQ------PLSVPVQQVHSPTSYLCRPDGTTTAYFPPVF 443
+S L S+ + G+ +A +Q L + + PT + +GT P+F
Sbjct: 3601 FSSSFL----SAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTG-----PIF 3651
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
KE+ N ++ G V L V G P ++QWF G + S D++ + +
Sbjct: 3652 IKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFV--------FDGDD 3703
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
+L+I T ED G +TC A NDYG +A L + S
Sbjct: 3704 HSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3740
Score = 83.6 bits (205), Expect = 1e-15
Identities = 65/204 (31%), Positives = 94/204 (46%), Gaps = 26/204 (12%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA-HKMLVRENGVHSL 969
PHF + +L V+ + CKV+G P P + W GK + D +++ + G H L
Sbjct: 24623 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24682
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNS--FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
II VT DA +Y ATN+ G S SLE+ V AK H P +E + G V
Sbjct: 24683 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK-IHLPKT-LEGMGAVHALRGEVV 24740
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLI----------QGATKE 1077
++ G P P I W+K + + DN+G+ +++ G ++
Sbjct: 24741 SIKIPFSGKPDPVITWQKGQDLI-----------DNNGHYQVIVTRSFTSLVFPNGVERK 24789
Query: 1078 DAGWYTVSAKNEAGIVSCTARLDV 1101
DAG+Y V AKN GI T LDV
Sbjct: 24790 DAGFYVVCAKNRFGIDQKTVELDV 24813
Score = 82.4 bits (202), Expect = 2e-15
Identities = 187/867 (21%), Positives = 319/867 (36%), Gaps = 161/867 (18%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
P F +KL S + + ECR+T G+PT V W +GK L +++ E G +
Sbjct: 1657 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC-S 1715
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQK 388
L A+ D+G TC ATN G+D TSA + ++ D +SL +S+ +P+ +K
Sbjct: 1716 LDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK-------DEKSLVEESQ---LPEGRK 1765
Query: 389 KTTSVS--LTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKE 446
+ + TGVTT + +PD Y PV
Sbjct: 1766 GLQRIEELERMAHEGALTGVTTDQKEKQ---------------KPD--IVLYPEPV---- 1804
Query: 447 LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTL 506
V EG+ CRV G P +V W+ G I+ S FR+ + I L
Sbjct: 1805 ----RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV---------RYDGIHYL 1851
Query: 507 VIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPP 566
I + D G +A N G +L + E + P P
Sbjct: 1852 DIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI-----------QQREDFRSVLRRAPEPR 1900
Query: 567 PILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHP--SRGVNGLIN 624
P K E+Q+V+ P + + ++ AER T+ P S +
Sbjct: 1901 PEFHVHE---PGKLQFEVQKVDRP-VDTTETKEVVKLKRAERITHEKVPEESEELRSKFK 1956
Query: 625 GKANSNKSLPTPAVLLSPTKEP---PPLLAKPK---LGFPKKASRTARIASDEEIQGTKD 678
+ AV L K+ LL K K L + K+ + + A EE + T
Sbjct: 1957 RRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIP 2016
Query: 679 AVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQ-----EPEEETANQ 733
D K+ + P++ ER+ + +G S F ++ +PE E
Sbjct: 2017 TFKPD---KIELSPSM---EAPKIF--ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKN 2068
Query: 734 EYKVSSCE-------QRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHY 786
K+ + + + E+ R + + D + V+ ++ E F ++ K
Sbjct: 2069 GVKIERSDRIYWYWPEDNVCELVIR-DVTAEDSASIMVKAINIAGETSSHAFLLVQAKQL 2127
Query: 787 KIF-----------EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
F + TF C + P K+ W+KDG ++ + D Y + D
Sbjct: 2128 ITFTQELQDVVAKEKDTMATFECETS-EPFVKVKWYKDGMEVH-EGDKYRMHSDRKVHFL 2185
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
T T D + ++ + + T +L+V+
Sbjct: 2186 SILTIDTSDAEDYSCVLVEDE--NVKTTAKLIVEGA------------------------ 2219
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
F++ D+ V E ++C VS + W + ++ +
Sbjct: 2220 --------------VVEFVKELQDIEVPESYSGELECIVSP-ENIEGKWYHNDVELKSNG 2264
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK 1015
+ + R G +L ++ VT D G Y+ + + + K +P ++
Sbjct: 2265 KYTITSR-RGRQNLTVKDVTKEDQGEYSFVIDGK--------KTTCKLKMKPRPIAILQG 2315
Query: 1016 LQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGAT 1075
L + V +G V+LE +V + + W K+ + + S DRV + D ++ LLI+ T
Sbjct: 2316 LSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPS-DRVHIVIDKQSHM-LLIEDMT 2372
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDVY 1102
KEDAG Y+ + A +S + R+ VY
Sbjct: 2373 KEDAGNYSFTI--PALGLSTSGRVSVY 2397
Score = 81.6 bits (200), Expect = 4e-15
Identities = 71/279 (25%), Positives = 119/279 (42%), Gaps = 37/279 (13%)
Query: 264 ALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL--HNTPDIQIHC 321
A+ P F++KL++ + EGSR+ ++ R TGNP P + W + H P I+I
Sbjct: 1503 AVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1562
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
G+ L I D+ YT A N +G DTT +V +E + F
Sbjct: 1563 TKGEA-ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-----------VEF----- 1605
Query: 382 AMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP 441
A P+ ++K + + G+ K + ++PL + Q L + P
Sbjct: 1606 AEPEPERK---LIIPRGTYRAKE-IAAPELEPLHLRYGQEQWEEGDLYDKEKQQ----KP 1657
Query: 442 VFTKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
F K+L + + ECR+ G P + V+W G ++ + R++ +
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINE------- 1710
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
C+L + D+GI TC A N YG+ ++A L+V
Sbjct: 1711 -FGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1748
Score = 79.0 bits (193), Expect = 2e-14
Identities = 63/240 (26%), Positives = 100/240 (41%), Gaps = 10/240 (4%)
Query: 772 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRD 829
E PFF+ KL ++ P F CR+ G+P + W DGK + + I
Sbjct: 1652 EKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEF 1711
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889
G CSL + D G T A N G + L+V+ + P G ++R
Sbjct: 1712 --GYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQR 1769
Query: 890 PRSRSRDSGDEN----EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQ 945
R + + Q+ +P + P + V EG+ R C+V+G P P ++W
Sbjct: 1770 IEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWY 1829
Query: 946 LDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
L+G+ +R + + VR +G+H L I S D G A N G ++L + +E
Sbjct: 1830 LNGQLIR--KSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1887
Score = 79.0 bits (193), Expect = 2e-14
Identities = 68/272 (25%), Positives = 110/272 (40%), Gaps = 50/272 (18%)
Query: 742 QRLISEIEYRLERSPVDESGDEVQYG----------DVPVENGMAPFFEMKLKHYKIFEG 791
+ LI +EY R + G E ++ DVP++ AP F+ +L++ +
Sbjct: 24582 KNLIEGLEYEF-RVKCENLGGESEWSEISEPITPKSDVPIQ---APHFKEELRNLNVRYQ 24637
Query: 792 MPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTI 851
T C+V G+PKP + W++ GK+I Y IQ G L + T DD Y +
Sbjct: 24638 SNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQV 24697
Query: 852 MAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRP 911
A N G +S T L V+ + + P
Sbjct: 24698 RATNQGGSVSGTASLEVE----------------------------------VPAKIHLP 24723
Query: 912 HFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLII 971
L+ G + G++ + SG P P ++WQ G+ + ++ H ++ SL+
Sbjct: 24724 KTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ-KGQDLIDNNGHYQVIVTRSFTSLVF 24782
Query: 972 -EPVTSRDAGIYTCIATNRAGQNSFSLELVVA 1002
V +DAG Y A NR G + ++EL VA
Sbjct: 24783 PNGVERKDAGFYVVCAKNRFGIDQKTVELDVA 24814
Score = 77.8 bits (190), Expect = 5e-14
Identities = 42/99 (42%), Positives = 63/99 (63%), Gaps = 8/99 (8%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP F + LQ+ V +G V L+ RV G P V+++R G+EIQ S DF+I Q+
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQE------- 155
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ +L+IAE +PED+G ++ +A N G ATSTA+L+V
Sbjct: 156 -GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 77.4 bits (189), Expect = 7e-14
Identities = 145/666 (21%), Positives = 234/666 (35%), Gaps = 132/666 (19%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
PV ++++ VA G + C ++ AP ++ QWF+ G EI +S I K
Sbjct: 4529 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSK------- 4581
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQ 560
I +L I T D G +TC A N+YGS + TA L VT E + + E
Sbjct: 4582 -YISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERK----- 4635
Query: 561 HFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVN 620
P P E + K+P E E V P +
Sbjct: 4636 ----PEPKEEVVLKSVLRKRP-------------------------EEEEPKVEPKK--- 4663
Query: 621 GLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAV 680
+ + PAV EPPP ++ P R +I ++ K A+
Sbjct: 4664 ---------LEKVKKPAV-----PEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAI 4709
Query: 681 -IQDLERKLRFKEDLLNNGQPRLTYEER-MARRLLGADSATVFNIQEPEEETANQEYKVS 738
+ E K + + ++ P + E +A + + P+EE A + +
Sbjct: 4710 PLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIK 4769
Query: 739 SCEQRLISEIEYRLER--------SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKI-- 788
++ S IE + P DE+ Q VP++ F ++K +
Sbjct: 4770 GVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLK------FVKEIKDIILTE 4823
Query: 789 --FEGMPVTFTCRVAGNPKPKI-YWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 845
F G F C V +P I W KDG I H I D LH L D
Sbjct: 4824 SEFVGSSAIFECLV--SPSTAITTWMKDGSNIRESPKHRFIADGKDR--KLHIIDVQLSD 4879
Query: 846 DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 905
G YT + + T +L+V E +
Sbjct: 4880 AGEYTCVLRLGNKEKTSTAKLVV---------------------------------EELP 4906
Query: 906 ERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENG 965
RF + ++TV +G+ + C+++ D+ W+ DGK V +
Sbjct: 4907 VRFVK----TLEEEVTVVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGL 4960
Query: 966 VHSLIIEPVTSRDAGIYTCIATNRAG-QNSFSLELVVAAKEAHKPPVFIEKLQNTGVADG 1024
+ +L I DAG YT N + S +++V ++ P+ + ++ G A
Sbjct: 4961 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTA-- 5018
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD-NHGYICLLIQGATKEDAGWYT 1083
C + P ++K +E D+ + +D NH Y L I+ A ED Y
Sbjct: 5019 ---IFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLY--LKIKNAMPEDIAEYA 5073
Query: 1084 VSAKNE 1089
V + +
Sbjct: 5074 VEIEGK 5079
Score = 76.6 bits (187), Expect = 1e-13
Identities = 68/269 (25%), Positives = 99/269 (36%), Gaps = 73/269 (27%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P P+ +Q+L+ V G ++G P P++ W+ E ++L +T G +
Sbjct: 3190 PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEY 3248
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387
TL++ EAF +D YTC A N G TTSA + +E D E +
Sbjct: 3249 TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVY----------- 3297
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKEL 447
A+I PL V P + CR GT
Sbjct: 3298 -------------------PPAIITPLQDTVTSEGQPARFQCRVSGT------------- 3325
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
L+V W+ + +I+ S FR+ Q E+ L
Sbjct: 3326 ---------------------DLKVSWYSKDKKIKPSRFFRMTQF--------EDTYQLE 3356
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQL 536
IAE +PED G +T A N G +STA L
Sbjct: 3357 IAEAYPEDEGTYTFVASNAVGQVSSTANL 3385
Score = 76.6 bits (187), Expect = 1e-13
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 12/195 (6%)
Query: 915 QAPG------DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS 968
+APG D+T + G+ ++ C++ G P PD+ W GK + +KM + H+
Sbjct: 24226 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS-SDGRTHT 24284
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
L + D G+YTCIATN G+ S +L++ A P +++ V G +R
Sbjct: 24285 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAV--GSTLR 24342
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L +G P P + W + L +++ +++ H ++ K AG Y V N
Sbjct: 24343 LHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSN 24401
Query: 1089 EAGIVSCTARLDVYI 1103
G V A LDV I
Sbjct: 24402 VFGTVD--AILDVEI 24414
Score = 75.1 bits (183), Expect = 3e-13
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 42/238 (17%)
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
P++ P + ++TV EG+ ++C +SG P+P ++W + + S +
Sbjct: 889 PVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIE-SSIDFQITF 947
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-------------- 1008
++G+ L+I + D+G +TC A N AG S S L V E +
Sbjct: 948 QSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEE 1007
Query: 1009 ---------------------------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQI 1041
P FI K + +G V C+V G P P +
Sbjct: 1008 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1067
Query: 1042 FWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
+WKK LT + G L+I +DAG YT+ +N+ G S +A L
Sbjct: 1068 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 74.3 bits (181), Expect = 6e-13
Identities = 78/323 (24%), Positives = 123/323 (38%), Gaps = 66/323 (20%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHN--TPDIQIHCEGGD 325
PAAP FI K Q++ EG V C+V GNP P V W G L + + + G+
Sbjct: 1033 PAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGE 1092
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ 385
L+I+ F DD G YT + N G + SA + E +D E L KS+ + Q
Sbjct: 1093 C-KLVISMTFADDAGEYTIVVRNKHGETSASASLLEE------ADYE-LLMKSQQEMLYQ 1144
Query: 386 AQKKTTSVSLTIGSSSP--------------------KTGVTTAVIQPL----------- 414
Q +G ++P K T V++
Sbjct: 1145 TQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSF 1204
Query: 415 ------SVPVQQVHSPTSYLCRPDG--------TTTAYFPPVFTKELQNTAVAEGQVVVL 460
+ + + + L DG + + F ++N + EG V
Sbjct: 1205 EERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTF 1264
Query: 461 ECRVRGAPPLQVQWFRQGSEIQDSPDFRI--LQKKPRSTAEPEEICTLVIAETFPEDAGI 518
C++ G P ++ W++ G I+ +++ LQ + +L I PED GI
Sbjct: 1265 HCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQ---------DGRASLRIPVVLPEDEGI 1315
Query: 519 FTCSARNDYGSATSTAQLVVTSA 541
+T A N G+A + +L V A
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPA 1338
Score = 73.9 bits (180), Expect = 8e-13
Identities = 60/269 (22%), Positives = 118/269 (43%), Gaps = 17/269 (6%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F ++++ + EG V C+++G P P++ W+ +GK + + Q+ +L I
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDS--ESLAFKSRAGAMPQAQKKT 390
+D G YT A+N G+ S ++++E A+ + + +L SR ++
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPD-GTTTAYFPPVFTKELQN 449
+ + ++ SP ++ A + P + SP L D + PVF + +
Sbjct: 1367 SPIRMSPARMSP-ARMSPARMSPARM------SPGRRLEETDESQLERLYKPVFVLKPVS 1419
Query: 450 TAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIA 509
EGQ + +V G P + WF G +I + +++ K+ + +L+I
Sbjct: 1420 FKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-------SLIIV 1472
Query: 510 ETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P D+G +T A+N G ++ + L V
Sbjct: 1473 PATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 72.4 bits (176), Expect = 2e-12
Identities = 53/186 (28%), Positives = 86/186 (46%), Gaps = 9/186 (4%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
D +EG + + ++ +++W + K V D K L +N ++L+I+ V + D
Sbjct: 4443 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTED 4499
Query: 979 -AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVP 1037
G Y C A N +G+ + S +L V + A PV K++ VA G+ + C + P
Sbjct: 4500 HQGEYVCEALNDSGKTATSAKLTVVKRAA---PVIKRKIEPLEVALGHLAKFTCEIQSAP 4556
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 1097
+ W K + + +D+ S+ + L I D G YT A NE G VSCTA
Sbjct: 4557 NVRFQWFKAGREI-YESDKCSIRSSKY-ISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 4614
Query: 1098 RLDVYI 1103
L V +
Sbjct: 4615 TLTVTV 4620
Score = 69.7 bits (169), Expect = 1e-11
Identities = 147/793 (18%), Positives = 273/793 (34%), Gaps = 80/793 (10%)
Query: 215 LSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFI 274
+ AS+S ++ Q RE S + + A+ + A R +
Sbjct: 26200 MEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARIL 26259
Query: 275 QKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEA 334
K RS V EG C G P P V W +G+ L + Q+ T I+
Sbjct: 26260 TKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYK-STFEISSV 26318
Query: 335 FEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVS 394
D G Y+ + N G + I+ A T+ S P+ + V
Sbjct: 26319 QASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTS---------PPRVKSPEPRVK 26369
Query: 395 LTIGSSSPKTGVTTAVIQPLSV-PVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVA 453
SPK + P +V P + +PT + PP T+ L+ A A
Sbjct: 26370 SPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH----LPVSAPPKITQFLK--AEA 26423
Query: 454 EGQVVVLECRVRGA--PPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
++ L C V + +V W++ G +++++ F+ T E L I
Sbjct: 26424 SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQ-FHYSADGTYE------LKINNL 26476
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGES-NNDHFQHFPPPPPILE 570
D G + C + G++ + Q + + + + + E+ +D E
Sbjct: 26477 TESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTE 26536
Query: 571 TSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSN 630
+ E S KP + + + + A E + G GK +
Sbjct: 26537 PKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS 26596
Query: 631 KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRF 690
+ + + T L + K ++ + + I+ KD Q K+
Sbjct: 26597 EDKGGFFLEIHKTDTSDSGLYTCTV---KNSAGSVSSSCKLTIKAIKDTEAQ----KVST 26649
Query: 691 KEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEY 750
++ Q + +E ++++ L ++ + + E+ +E + +
Sbjct: 26650 QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAAT 26709
Query: 751 RLERSPVDESGDEVQYGDVPVENGMAPFFEMKL--KHYKIFEGMPVTFTCRVAGNPKPKI 808
LE+S V E + V E+K I EG + +AG K
Sbjct: 26710 SLEKSIVHEEITKTSQASEEVRT----HAEIKAFSTQMSINEGQRLVLKANIAGATDVK- 26764
Query: 809 YWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
W +G +++ ++ D T ++ + D+G T ++ +G + C L +
Sbjct: 26765 -WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHR--DEGILTCISKTKEGIVKCQYDLTL 26821
Query: 869 QAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLC 928
S + +PRS++ + EG+
Sbjct: 26822 --------SKELSDAPAFISQPRSQN---------------------------INEGQNV 26846
Query: 929 RMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATN 988
C++SG P+P++ W + P+ S++ + R V+SL I + D+G YT A N
Sbjct: 26847 LFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKN 26905
Query: 989 RAGQNSFSLELVV 1001
GQ S + L+V
Sbjct: 26906 FRGQCSATASLMV 26918
Score = 69.3 bits (168), Expect = 2e-11
Identities = 120/637 (18%), Positives = 230/637 (36%), Gaps = 71/637 (11%)
Query: 255 RKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT 314
RK+ P+ + + P + L+ V+ S + TG P P W +GK +
Sbjct: 26533 RKTEPKAPEPIS--SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG 26590
Query: 315 PDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL 374
++ + G L I + D+G YTC N +GS ++S ++ I+ T++ S
Sbjct: 26591 GKYKLSEDKGGFF-LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVST 26649
Query: 375 AFKSRAGAMPQA-------QK--KTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT 425
S +A QK ++ + ++ S K + + L + + T
Sbjct: 26650 QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAAT 26709
Query: 426 SY---LCRPDGTTTAYFPPVFTKELQNTA------VAEGQVVVLECRVRGAPPLQVQWFR 476
S + + T T+ + A + EGQ +VL+ + GA V+W
Sbjct: 26710 SLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT--DVKWVL 26767
Query: 477 QGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL 536
G E+ +S ++R + ++ TL I + D GI TC ++ G L
Sbjct: 26768 NGVELTNSEEYRY------GVSGSDQ--TLTIKQASHRDEGILTCISKTKEGIVKCQYDL 26819
Query: 537 VVTSANTENCSYESMGESNN-DHFQHFPPPPPILETSSLELA-SKKPSEIQQVNNPELGL 594
++ ++ ++ S S N + Q+ I S E+ K I +N +
Sbjct: 26820 TLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR 26879
Query: 595 SRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPK 654
SR ++ A +G + + N G+ ++ SL ++ P++E
Sbjct: 26880 SRNVYSLEIRNASVSDSGKYTIKAKN--FRGQCSATASLMVLPLVEEPSREV-------- 26929
Query: 655 LGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLG 714
R + D +QG+ + + K++ + + +
Sbjct: 26930 ---------VLRTSGDTSLQGSFSSQSVQMSAS---KQEASFSSFSSSSASSMTEMKFAS 26977
Query: 715 ADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENG 774
+ ++ ++QE E ++ + S +L S L+ G
Sbjct: 26978 MSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGI----------------RG 27021
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
+ P E I EG +T C G P P++ W G++I + + D
Sbjct: 27022 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 27081
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAV 871
+L D G YT+ N G S T + ++++
Sbjct: 27082 TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27118
Score = 67.4 bits (163), Expect = 7e-11
Identities = 136/648 (20%), Positives = 237/648 (36%), Gaps = 122/648 (18%)
Query: 444 TKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
TK ++N V E + EC V P + W + G EI+ S F+I+ +
Sbjct: 2839 TKTMKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQG-------- 2887
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLV--------VTSANTENCSYESMGE 553
++ L+I T ED+ +T ND SAT T + + + + ++E
Sbjct: 2888 KLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVN 2947
Query: 554 SNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGV 613
++ I T ++ +KK + + N G +AA+
Sbjct: 2948 YEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFG----------DAADYT---- 2993
Query: 614 HPSRGVNGLINGKANSNKSLPTPAVLLSPTK--EPPPLLAKPKLGFPKKASR----TARI 667
+ GKA S +L A + K + +L K + F + S +
Sbjct: 2994 --------FVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWM 3045
Query: 668 ASDEEIQGTKDAVIQD---LERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATV---- 720
D+E+Q T IQ + R L + + G+ + ++ L + V
Sbjct: 3046 KDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRS 3105
Query: 721 --FNIQEPEEETANQEYKVS-----------------SCEQRLISEIEYRLERSPVDES- 760
+Q E++ A E++V+ ++R +E R+ R + E+
Sbjct: 3106 IKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETR 3165
Query: 761 -GDEVQYGDVPVENGMA----------PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIY 809
D +Y V N + P +L+ + G P F ++G P+PKI
Sbjct: 3166 QSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKIS 3225
Query: 810 WFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ 869
W+K+ + +S + + T L + +D YT A N G + + L V+
Sbjct: 3226 WYKEEQLLSTGFKCKFLHDGQEYTLLL--IEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283
Query: 870 AVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCR 929
P V P D+ P+ + P + D EG+ R
Sbjct: 3284 V--------------PEVVSP--------DQEMPV----YPPAIITPLQDTVTSEGQPAR 3317
Query: 930 MDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR 989
C+VSG +SW K ++P +M E+ + L I D G YT +A+N
Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGTYTFVASNA 3375
Query: 990 AGQNS----FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRV 1033
GQ S SLE+ +++ V E ++ VAD + E ++
Sbjct: 3376 VGQVSSTANLSLEVQALDRQSSGKDV-RESAKSQAVADSSFTKEESKI 3422
Score = 65.5 bits (158), Expect = 3e-10
Identities = 38/105 (36%), Positives = 55/105 (52%), Gaps = 3/105 (2%)
Query: 258 HPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDI 317
HP P + P F + L + E EG V E RV+G P P ++W +G+ L P+I
Sbjct: 25480 HPPPTDST---LRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNI 25536
Query: 318 QIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+I EG D + L I + +DTG Y ATN +GS + A + +E
Sbjct: 25537 EIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25581
Score = 64.7 bits (156), Expect = 5e-10
Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Query: 1009 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
PP + L+N V +G V LEC + G P P + W +E+ + S D Q G
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQS--GIAR 953
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 1104
L+I+ A ED+G +T SA NEAG VS + L V +S
Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 989
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/127 (31%), Positives = 66/127 (51%), Gaps = 4/127 (3%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT--PDIQIHCEGGDLH 327
AP F Q L+S V EGS E ++G P P V WF +G+ + + P +QI G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA- 63
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL-AFKSRAGAMPQA 386
L I + ++GRY+ ATN SG T++AE+ ++ ++ + + L + R G+ +
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 387 QKKTTSV 393
Q + T +
Sbjct: 124 QVRVTGI 130
Score = 62.4 bits (150), Expect = 2e-09
Identities = 198/944 (20%), Positives = 315/944 (33%), Gaps = 199/944 (21%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F L+ V E + EC +T V W +G ++ + D G H L+I
Sbjct: 5183 FAVPLKDVTVPERRQARFECVLTREAN--VIW-SKGPDIIKSSDKFDIIADGKKHILVIN 5239
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGA---------SSTDSDSESLAF------- 376
++ DD G YT TSA +F+ G T + E+ F
Sbjct: 5240 DSQFDDEGVYTAEVEGKK----TSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHE 5295
Query: 377 KSRAGAMPQAQKKTTSVSLTIGSSSP--KTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT 434
K K TS ++ I S K + + +S Q+ + L
Sbjct: 5296 KMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDIS----QIKAQVKELSSTAQL 5351
Query: 435 TTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKP 494
P FT +L + E + L+C V P V+WF+ G EI SP + I
Sbjct: 5352 KVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSPKYSIKADGL 5409
Query: 495 RSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT----------E 544
R L I + +D G + C D A T + + E
Sbjct: 5410 RR--------ILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGE 5461
Query: 545 NCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFN 604
+E + H Q P+ + E+ I ++N +LG++ ++ F
Sbjct: 5462 TAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTG---EVSFQ 5518
Query: 605 AAERETNGVHPSRGVNGLINGKANSN-KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASR 663
AA N K+ +N K P + ++P + + K + F + SR
Sbjct: 5519 AA-----------------NAKSAANLKVKELPLIFITPLSD-VKVFEKDEAKFECEVSR 5560
Query: 664 ----------TARIASDEEIQGTKD----------AVIQDLERKLRFKEDLLNNGQ---- 699
T I D+ + KD A +D + + ED +G+
Sbjct: 5561 EPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIE 5620
Query: 700 -PRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVD 758
RL + + + VF ++ + N K +QRL + ++
Sbjct: 5621 GIRLKFLTPLKDVTAKEKESAVFTVELSHD---NIRVKWFKNDQRLHTTRSVSMQDEGKT 5677
Query: 759 ESGDEVQYGDVPVEN---------GMA-----------PFFEMKLKHYKIFEGMPVTFTC 798
S + + D+ +++ GM+ P+F KL+ Y E V C
Sbjct: 5678 HS---ITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQC 5734
Query: 799 RVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDD-GNYTIMAANPQ 857
++ P + WFKDGK+I P + DG + L D G YT
Sbjct: 5735 EISKADAP-VKWFKDGKEIKPSKNAVI---KADGKKRMLILKKALKSDIGQYTCDC---- 5786
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP 917
G +G+L ++ + P R + S D+ + LQ P
Sbjct: 5787 GTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIH-ANWKLKGEALLQTP 5845
Query: 918 GDLTVQEGKL-------CRMD---------------------CKVSGLPTP--------- 940
+EGK+ CR+D +V GL P
Sbjct: 5846 DCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAG 5905
Query: 941 --------------DLSWQLDGKPVRPDSAHKMLVRENG-VHSLIIEPVTSRDAGIYTCI 985
+ W L GK + P + K++ R G VH+L + V DAG
Sbjct: 5906 ETATFDCELSYEDIPVEWYLKGKKLEP--SDKVVPRSEGKVHTLTLRDVKLEDAGEVQLT 5963
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPV-FIEKLQNTGVADGYPVRLECRVLGVPPPQIFWK 1044
A F + KE PPV F + L++ V +G LEC V ++ W
Sbjct: 5964 A------KDFKTHANLFVKE---PPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWF 6013
Query: 1045 KENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
K + S + + D L+I T ED YT AK+
Sbjct: 6014 KNGTEILKS-KKYEIVADGR-VRKLVIHDCTPEDIKTYTCDAKD 6055
Score = 61.6 bits (148), Expect = 4e-09
Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 7/143 (4%)
Query: 770 PVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD 829
P ++ + P F+ L + + EG V F RV+G P P + W KDG+ +S + I
Sbjct: 25483 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEG 25542
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHP-HVR 888
LD +LH + +D G Y + A N G SC L V+ + + + +S H HV+
Sbjct: 25543 LD-YYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQ 25601
Query: 889 RP-----RSRSRDSGDENEPIQE 906
+ R SG E+ P+ +
Sbjct: 25602 KQIDKTLRMAEILSGTESVPLTQ 25624
Score = 61.2 bits (147), Expect = 5e-09
Identities = 44/184 (23%), Positives = 76/184 (41%), Gaps = 4/184 (2%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P P F+++L+ A+G E V G P P V WF E K+L + I
Sbjct: 3764 PCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 3823
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASSTDSDSESLAFKSRAGAMPQ 385
T I+ + +D+G Y C A N G T +AE V +E TD+ ++ + PQ
Sbjct: 3824 TFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQ 3883
Query: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTK 445
K +V T V +++ + + ++ + + ++ P+ +
Sbjct: 3884 TPLKGPAVEALDSEQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQL--PLGAQ 3941
Query: 446 ELQN 449
ELQ+
Sbjct: 3942 ELQS 3945
Score = 61.2 bits (147), Expect = 5e-09
Identities = 66/266 (24%), Positives = 105/266 (39%), Gaps = 25/266 (9%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+ ++ L S EV E E ++ + W +G+ L TPD +I E G +H+L++
Sbjct: 5803 KLVRPLHSVEVMETETARFETEISEDDI-HANWKLKGEALLQTPDCEIK-EEGKIHSLVL 5860
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG-----------ASSTDSDSESLAFKSRA 380
D TG A N S + + G A T + L+++
Sbjct: 5861 HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP 5920
Query: 381 GAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFP 440
KK + S K V T ++ + + T+ + P
Sbjct: 5921 VEWYLKGKKLEPSDKVVPRSEGK--VHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEP 5978
Query: 441 PV-FTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PV FTK L++ V EG VLEC V +V+WF+ G+EI S + I+
Sbjct: 5979 PVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIV--------A 6029
Query: 500 PEEICTLVIAETFPEDAGIFTCSARN 525
+ LVI + PED +TC A++
Sbjct: 6030 DGRVRKLVIHDCTPEDIKTYTCDAKD 6055
Score = 60.8 bits (146), Expect = 7e-09
Identities = 36/94 (38%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKE-LHNTPDIQIHCEGGDLHT 328
AP F ++LR+ V S L C+VTG+P P V+W+ +GKE + + +I G H
Sbjct: 24622 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24681
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
LIIA +DD Y ATN GS + +A + +E
Sbjct: 24682 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24715
Score = 58.9 bits (141), Expect = 3e-08
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP ++++ G L C++ G P P ++W+ GKEL + ++ + G HTL
Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSD-GRTHTL 24285
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+ ++D G YTC+ATN G TS+++ ++
Sbjct: 24286 TVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24318
Score = 58.2 bits (139), Expect = 4e-08
Identities = 68/279 (24%), Positives = 108/279 (38%), Gaps = 25/279 (8%)
Query: 262 HSALHFPAAP-RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIH 320
H+ L P F + L Q V EG+ LEC V+ +V+WF G E+ + +I
Sbjct: 5970 HANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIV 6028
Query: 321 CEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSA----EVFIEGASSTDSDSESLAF 376
+ G + L+I + +D YTC A + S + F+ + + +A
Sbjct: 6029 AD-GRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMAR 6087
Query: 377 KSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC-----RP 431
+ A+ K I ++ ++ L + + Y C R
Sbjct: 6088 FECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTART 6147
Query: 432 DGTTTAY-FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
G T VFTK L N V+E + L C V P +V W++ EI ++ + IL
Sbjct: 6148 SGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEIL 6206
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTC---SARND 526
+ + LVI EDAG + C S+R D
Sbjct: 6207 TEGRKR--------ILVIQNAHLEDAGNYNCRLPSSRTD 6237
Score = 58.2 bits (139), Expect = 4e-08
Identities = 68/290 (23%), Positives = 101/290 (34%), Gaps = 73/290 (25%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F L ++ G V +T +P P V W+ G+++ + + +
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKY---------- 25434
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
FE D G Y L N + +TD D+E T
Sbjct: 25435 ---TFESDKGLYQ-LTIN---------------SVTTDDDAEY----------------T 25459
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT 450
G S K +T + P PT RP +F + L N
Sbjct: 25460 VVARNKYGEDSCKAKLTVTLHPP----------PTDSTLRP----------MFKRLLANA 25499
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
EGQ V E RV G PP ++W + G + P+ I+ E + L I +
Sbjct: 25500 ECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH-------EGLDYYALHIRD 25552
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQ 560
T PED G + +A N GS + A L V + ++S E + H Q
Sbjct: 25553 TLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSK-EEHERHVQ 25601
Score = 57.4 bits (137), Expect = 7e-08
Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 8/143 (5%)
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG----VAD 1023
S ++E + + A N G++ SL L V ++ PP +L G V
Sbjct: 9048 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKA 9107
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD----NHGYICLLIQGATKEDA 1079
G PV + V G+P P+I W K + TD + + ++ + L I A +ED
Sbjct: 9108 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 9167
Query: 1080 GWYTVSAKNEAGIVSCTARLDVY 1102
G YTV+A N G V ++VY
Sbjct: 9168 GTYTVTASNRLGSVFRNVHVEVY 9190
Score = 55.1 bits (131), Expect = 4e-07
Identities = 60/277 (21%), Positives = 110/277 (39%), Gaps = 45/277 (16%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F KL+ E V L+C ++ P V+WF +GKE+ + + I +G LI
Sbjct: 5713 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKK-RMLI 5770
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
+ +A + D G+YTC G+D TS ++ D + + ++ + +T
Sbjct: 5771 LKKALKSDIGQYTC----DCGTDKTSGKL--------DIEDREIKLVRPLHSVEVMETET 5818
Query: 391 TSVSLTIGSSSPKTG---VTTAVIQPLSVPVQQ---VHSPTSYLCRPDGTTTAYFPPVFT 444
I A++Q +++ +HS + CR D T F
Sbjct: 5819 ARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANV 5878
Query: 445 KE----------------LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
K L++ V G+ +C + + V+W+ +G +++ S
Sbjct: 5879 KSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPSD--- 5934
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARN 525
+ PRS ++ TL + + EDAG +A++
Sbjct: 5935 --KVVPRSEG---KVHTLTLRDVKLEDAGEVQLTAKD 5966
Score = 54.3 bits (129), Expect = 6e-07
Identities = 47/194 (24%), Positives = 82/194 (42%), Gaps = 13/194 (6%)
Query: 757 VDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 816
+++SG + V AP + K++ ++ G FTC + P + WFK G++
Sbjct: 4509 LNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE 4568
Query: 817 ISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV-------- 868
I +SD +I R SL + + D G YT A+N G +SCT L V
Sbjct: 4569 IY-ESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKK 4626
Query: 869 --QAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGK 926
+ + +R P+ V R R + E + + E+ +P + P V+E +
Sbjct: 4627 VRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKL-EKVKKPAVPEPPPPKPVEEVE 4685
Query: 927 LCRMDCKVSGLPTP 940
+ + + +P P
Sbjct: 4686 VPTVTKRERKIPEP 4699
Score = 54.3 bits (129), Expect = 6e-07
Identities = 59/258 (22%), Positives = 105/258 (40%), Gaps = 44/258 (17%)
Query: 773 NGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG 832
+G AP ++K G +C++ G P P I W++ GK++ +S Y + D
Sbjct: 24224 SGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSD-GR 24281
Query: 833 TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 892
T +L +D+G YT +A N G + + +L++QA +P HP
Sbjct: 24282 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA---------TPQFHP------- 24325
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
P++E+++ G R+ G P P ++W G+ +
Sbjct: 24326 --------GYPLKEKYYG------------AVGSTLRLHVMYIGRPVPAMTW-FHGQKLL 24364
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSR-DAGIYTCIATNRAGQNSFSLELVVAAKEAHKP-- 1009
+S + + L+++ V + AG Y +N G L++ + K KP
Sbjct: 24365 QNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDK-PDKPTG 24423
Query: 1010 PVFIEK-LQNTGVADGYP 1026
P+ IE L+N+ V P
Sbjct: 24424 PIVIEALLKNSAVISWKP 24441
Score = 53.5 bits (127), Expect = 1e-06
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 1/97 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
LTV+ G +D V G P P +SW+ DG ++P KM ++ N + +L + V +D+
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 13058
Query: 980 GIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
G YT A N +G S +++L V K V I K+
Sbjct: 13059 GDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKM 13095
Score = 52.8 bits (125), Expect = 2e-06
Identities = 77/305 (25%), Positives = 118/305 (38%), Gaps = 60/305 (19%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
F L+ + EG C V+ K+ WFK+G +I KS Y I D L
Sbjct: 5982 FTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEIL-KSKKYEIVAD-GRVRKLVI 6038
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
T +D YT A + + SC ++ PHV
Sbjct: 6039 HDCTPEDIKTYTCDAKD--FKTSCNLNVVP----------------PHVE---------- 6070
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHK 958
FL+ DL V+E ++ R +C++S + W DG ++ +
Sbjct: 6071 --------------FLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAEIKKGKKYD 6115
Query: 959 MLVRENGVHSLIIEPVTSRDAGIYTC-IATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQ 1017
++ + V L+I D Y+C + T R S L V +EA VF + L
Sbjct: 6116 -IISKGAVRILVINKCLLDDEAEYSCEVRTART-----SGMLTVLEEEA----VFTKNLA 6165
Query: 1018 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKE 1077
N V++ ++L C V P ++ W K +E + T R + + I L+IQ A E
Sbjct: 6166 NIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEII-ETGRYEILTEGRKRI-LVIQNAHLE 6222
Query: 1078 DAGWY 1082
DAG Y
Sbjct: 6223 DAGNY 6227
Score = 52.8 bits (125), Expect = 2e-06
Identities = 31/94 (32%), Positives = 47/94 (50%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
P F E+L+N V L C+V G P P + W ++ + + + + + GY L
Sbjct: 24623 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24682
Query: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
+I T +DA Y V A N+ G VS TA L+V +
Sbjct: 24683 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEV 24716
Score = 52.4 bits (124), Expect = 2e-06
Identities = 34/100 (34%), Positives = 46/100 (46%), Gaps = 10/100 (10%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDS--PDFRILQKKPRSTA 498
P FT+ LQ+ V EG E + G P +V WFR G I S P +I R+
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA-- 63
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L I ++G ++ A N G ATSTA+L+V
Sbjct: 64 ------KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 51.6 bits (122), Expect = 4e-06
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 25/271 (9%)
Query: 277 LRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE 336
+++ EV E EC V+ P + W G E+ + +I +G LH LII
Sbjct: 2842 MKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG-KLHQLIIMNTST 2899
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE---SLAFK---SRAGAMPQAQKKT 390
+D+ YT + N S T + + + D ++E ++ F+ + G + K
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP---VFTKEL 447
+ T +T T + +V T + T T Y F K +
Sbjct: 2960 VEIKST-DKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHI 3018
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
++ V E + + EC V P + VQW + E+Q + +I ++K + L+
Sbjct: 3019 KDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEK--------YVHRLL 3069
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
I T DAG +T A G STA+L V
Sbjct: 3070 IPSTRMSDAGKYTVVA----GGNVSTAKLFV 3096
Score = 50.8 bits (120), Expect = 7e-06
Identities = 51/270 (18%), Positives = 102/270 (37%), Gaps = 28/270 (10%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP+ ++++SQ V +GS + RV G P P W+ G ++ + I + ++ L
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCEL 2090
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG----------ASSTDSDSESLAFKSR 379
+I + +D+ A N +G ++ A + ++ + +++A
Sbjct: 2091 VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFEC 2150
Query: 380 AGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC----RPDGTT 435
+ P + K + + + + LS+ Y C + T
Sbjct: 2151 ETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKT 2210
Query: 436 TAYF-----PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
TA F KELQ+ V E LEC V ++ +W+ E++ + + I
Sbjct: 2211 TAKLIVEGAVVEFVKELQDIEVPESYSGELECIV-SPENIEGKWYHNDVELKSNGKYTIT 2269
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFT 520
++ R L + + ED G ++
Sbjct: 2270 SRRGRQ--------NLTVKDVTKEDQGEYS 2291
Score = 50.8 bits (120), Expect = 7e-06
Identities = 35/127 (27%), Positives = 63/127 (49%), Gaps = 3/127 (2%)
Query: 905 QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 964
+E+ P L P +T++ GK R++ V G P P W+ G+ S+H + + +
Sbjct: 12589 KEQLLPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWK-KGEDEVVTSSHLAVHKAD 12646
Query: 965 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA-AKEAHKPPVFIEKLQNTGVAD 1023
LII+ VT +D+G Y+ A N +G ++ +++VV A +PP I + +
Sbjct: 12647 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL 12706
Query: 1024 GYPVRLE 1030
+ + LE
Sbjct: 12707 SWHIPLE 12713
Score = 50.8 bits (120), Expect = 7e-06
Identities = 57/257 (22%), Positives = 97/257 (37%), Gaps = 55/257 (21%)
Query: 284 EGSRVYLECRVTG-NPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRY 342
EG V C++ + + +V W+ ++L N+ +I E G + L + + + D G Y
Sbjct: 25276 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDG-VAILYVKDITKLDDGTY 25334
Query: 343 TCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSP 402
C N G D++ AE+F++G E + R M + +++T ++ L
Sbjct: 25335 RCKVVNDYGEDSSYAELFVKGV------REVYDYYCRR-TMKKIKRRTDTMRL------- 25380
Query: 403 KTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLEC 462
L RP P FT L N G+ V
Sbjct: 25381 -------------------------LERP---------PEFTLPLYNKTAYVGENVRFGV 25406
Query: 463 RVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCS 522
+ P V W++ G +I+ + K + + + L I +D +T
Sbjct: 25407 TITVHPEPHVTWYKSGQKIKPGDN-----DKKYTFESDKGLYQLTINSVTTDDDAEYTVV 25461
Query: 523 ARNDYGSATSTAQLVVT 539
ARN YG + A+L VT
Sbjct: 25462 ARNKYGEDSCKAKLTVT 25478
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/95 (35%), Positives = 56/95 (58%), Gaps = 5/95 (5%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKK-ENESLTHSTDR 1056
E V AKE PP + Q T + G +R+E V G P P WKK E+E +T S
Sbjct: 12583 EGVYEAKEQLLPPKILMPEQIT-IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSS--H 12639
Query: 1057 VSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
+++H+ + I L+I+ T++D+G+Y+++A+N +G
Sbjct: 12640 LAVHKADSSSI-LIIKDVTRKDSGYYSLTAENSSG 12673
Score = 50.1 bits (118), Expect = 1e-05
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHS-TDRVSMHQDNHGYIC 1068
PVF+ K + +G R + +V+G P P+ FW + + + + T +V + +D G
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED--GTQS 1468
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISRH 1106
L+I AT D+G +TV A+N AG S + L V H
Sbjct: 1469 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH 1506
Score = 49.7 bits (117), Expect = 2e-05
Identities = 41/158 (25%), Positives = 67/158 (42%), Gaps = 5/158 (3%)
Query: 205 LSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSA 264
L P ++ +L S S+SP+ M SP AR + R+ S
Sbjct: 1350 LEPVSRIRSLSPRSVSRSPIR----MSPARMSP-ARMSPARMSPARMSPGRRLEETDESQ 1404
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
L P F+ K S + EG + +V G P P WF +G+++ N ++ +
Sbjct: 1405 LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED 1464
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+LII A D+G +T +A N +G + S + +E
Sbjct: 1465 GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1502
Score = 49.7 bits (117), Expect = 2e-05
Identities = 73/280 (26%), Positives = 110/280 (39%), Gaps = 29/280 (10%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F + L + EV+E + L C V+ P V W+ +E+ T +I EG L+I
Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRK-RILVIQ 6217
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFI-EGASSTDSDSESLAFKS--RAGAMPQAQKK 389
A +D G Y C S T +V + E A+ S ++L +A + K+
Sbjct: 6218 NAHLEDAGNYNCRLP----SSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKE 6273
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT-----SYLCRPDGTTTAYFPPVFT 444
+ V + ++G VI V V T +Y+ A V
Sbjct: 6274 SFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIE 6333
Query: 445 K-----ELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
K L++T V E Q VV C V + +WFR I DS + ILQK
Sbjct: 6334 KLRIVVPLKDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQK------- 6385
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYG-SATSTAQLVV 538
+ + TL I + +D + S N G + S A L+V
Sbjct: 6386 -DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 6424
Score = 49.3 bits (116), Expect = 2e-05
Identities = 41/167 (24%), Positives = 69/167 (41%), Gaps = 22/167 (13%)
Query: 195 GESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDL----- 249
G + S DSG ++ + +++ ++D+ + E + P R Q ++L
Sbjct: 1719 GVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH 1778
Query: 250 -----AVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRW 304
V ++K +P L +P R V EG CRVTG P P+V W
Sbjct: 1779 EGALTGVTTDQKEKQKPDIVL-YPEPVR---------VLEGETARFRCRVTGYPQPKVNW 1828
Query: 305 FCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSG 351
+ G+ + + ++ +G +H L I + DTG A NP G
Sbjct: 1829 YLNGQLIRKSKRFRVRYDG--IHYLDIVDCKSYDTGEVKVTAENPEG 1873
Score = 49.3 bits (116), Expect = 2e-05
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 8/98 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P KE+++ G+ L C++ G P ++W+R G E ++Q + +
Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKE--------LIQSRKYKMSSD 24279
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
TL + ED G++TC A N+ G ++++L++
Sbjct: 24280 GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLL 24317
Score = 49.3 bits (116), Expect = 2e-05
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 8/99 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE-IQDSPDFRILQKKPRSTAE 499
P F +EL+N V L C+V G P V+W+RQG E I D +RI + K
Sbjct: 24623 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFK------ 24676
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L+IA +DA ++ A N GS + TA L V
Sbjct: 24677 -GGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24714
Score = 48.1 bits (113), Expect = 4e-05
Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 5/145 (3%)
Query: 960 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFS-LELVVAAKEAHKPPVFIEKLQN 1018
+V E+ V + ++ ++S + A N G++ L + V AK+ P
Sbjct: 17956 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 18015
Query: 1019 TGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKED 1078
+ G +++E V+G P P I W K+ E L +T RV++ + + L I+ K+D
Sbjct: 18016 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT-RVNVEETATSTV-LHIKEGNKDD 18073
Query: 1079 AGWYTVSAKNEAGIVSCTARLDVYI 1103
G YTV+A N AG + T L V +
Sbjct: 18074 FGKYTVTATNSAG--TATENLSVIV 18096
Score = 47.8 bits (112), Expect = 6e-05
Identities = 64/261 (24%), Positives = 98/261 (37%), Gaps = 49/261 (18%)
Query: 619 VNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKD 678
+ GL+ G+ + + P E P+LA LG P R + TK
Sbjct: 8951 ITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYT------ERTKS 9004
Query: 679 AVIQDLERKLRFKEDLLNNGQPRLTYE-----------ERMARRLLGADSATVFNIQEPE 727
+ D +KE N G P Y ER+ +RL S V N+ E +
Sbjct: 9005 TITLD------WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQ 9058
Query: 728 EETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLK--- 784
E++V + + I E E L + V +Q +VP P +++L
Sbjct: 9059 M----YEFRVKAVNE--IGESEPSLPLNVV------IQDDEVP------PTIKLRLSVRG 9100
Query: 785 -HYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD----LDGTCSLHTT 839
K+ G PV V G P PKI W K+ I +D I ++ + L
Sbjct: 9101 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 9160
Query: 840 ASTLDDDGNYTIMAANPQGRI 860
+ +D G YT+ A+N G +
Sbjct: 9161 KAVREDKGTYTVTASNRLGSV 9181
Score = 47.8 bits (112), Expect = 6e-05
Identities = 40/145 (27%), Positives = 70/145 (48%), Gaps = 21/145 (14%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V+A N++G+S G P + + + +P + F + +QA DL
Sbjct: 17980 VKAYNEKGKSDPRVLGVPVIAKDLTI--------QPSLKLPFNTYSIQAGEDL------- 18024
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI-IEPVTSRDAGIYTCIA 986
+++ V G P P++SW DG+P++ + ++ V E +++ I+ D G YT A
Sbjct: 18025 -KIEIPVIGRPRPNISWVKDGEPLKQTT--RVNVEETATSTVLHIKEGNKDDFGKYTVTA 18081
Query: 987 TNRAGQNSFSLELVVAAKEAHKPPV 1011
TN AG + +L ++V K PPV
Sbjct: 18082 TNSAGTATENLSVIVLEKPG--PPV 18104
Score = 47.4 bits (111), Expect = 8e-05
Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 5/110 (4%)
Query: 256 KSHPQ----PHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL 311
KS P+ P A P + + G + +E V G P P + W +G+ L
Sbjct: 17988 KSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL 18047
Query: 312 HNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
T + + E L I E +DD G+YT ATN +G+ T + V +
Sbjct: 18048 KQTTRVNVE-ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096
Score = 46.6 bits (109), Expect = 1e-04
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDD 338
S V G + +E ++G P P + W +G L T I + + DL TL I E +DD
Sbjct: 16933 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV-TDSLDLTTLSIKETHKDD 16991
Query: 339 TGRYTCLATNPSGSDTTSAEV 359
G+Y N G T S E+
Sbjct: 16992 GGQYGITVANVVGQKTASIEI 17012
Score = 46.2 bits (108), Expect = 2e-04
Identities = 48/182 (26%), Positives = 77/182 (42%), Gaps = 19/182 (10%)
Query: 925 GKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTC 984
G +C VS T +W DG +R H+ + + L I V DAG YTC
Sbjct: 4828 GSSAIFECLVSP-STAITTWMKDGSNIRESPKHRFIA-DGKDRKLHIIDVQLSDAGEYTC 4885
Query: 985 IATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQN-TGVADGYPVRLECRVLGVPPPQIFW 1043
+ + + + +LVV P F++ L+ V G P+ L C + + W
Sbjct: 4886 VLRLGNKEKTSTAKLVVE----ELPVRFVKTLEEEVTVVKGQPLYLSCELN--KERDVVW 4939
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLL----IQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
+K+ + + R+ G I L+ I A DAG YTV+ +N A + C++ +
Sbjct: 4940 RKDGKIVVEKPGRIVP-----GVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSSCV 4993
Query: 1100 DV 1101
V
Sbjct: 4994 KV 4995
Score = 46.2 bits (108), Expect = 2e-04
Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query: 997 LELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDR 1056
L + V AK+ PP F V G ++++ +G P P + W K+N L +T R
Sbjct: 15830 LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTT-R 15888
Query: 1057 VSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
V+ + + L I+ A +ED G Y V N AG
Sbjct: 15889 VNAESTENNSL-LTIKDACREDVGHYVVKLTNSAG 15922
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 12/138 (8%)
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRP-DSAHKMLVRENGVHSLIIE 972
LQ D V EG + +++ KVS L + + W DG+ V+P D H ++ +++ H L+IE
Sbjct: 2313 LQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQS--HMLLIE 2369
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
+T DAG Y+ +L L + + + I L++ V +G LEC+
Sbjct: 2370 DMTKEDAGNYSFTIP--------ALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECK 2421
Query: 1033 VLGVPPPQIFWKKENESL 1050
V + W +E +
Sbjct: 2422 VSVPDVTSVKWYLNDEQI 2439
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
AAP +K+ EVA G C + P R +WF G+E++ + I + +
Sbjct: 4527 AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR-SSKYISS 4585
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
L I D G YTC A+N GS + +A + +
Sbjct: 4586 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTGRYT 343
G LE V+G P P + W +GKEL T ++I D T L+ ++ D+G YT
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI--ADFSTNLVNKDSTRRDSGAYT 15228
Query: 344 CLATNPSG 351
ATNP G
Sbjct: 15229 LTATNPGG 15236
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G +RL V G PPP I W K+ L ++ Y L++ + DAG YT
Sbjct: 23156 GASLRLMVSVSGRPPPVITWSKQGIDLASR----AIIDTTESYSLLIVDKVNRYDAGKYT 23211
Query: 1084 VSAKNEAGIVSCTARLDVY 1102
+ A+N++G S T + VY
Sbjct: 23212 IEAENQSGKKSATVLVKVY 23230
Score = 45.4 bits (106), Expect = 3e-04
Identities = 84/380 (22%), Positives = 138/380 (36%), Gaps = 77/380 (20%)
Query: 760 SGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISP 819
+G+ + G + V G L + E F C VA NP K W +DGK +
Sbjct: 2560 AGENMTSGKLTVAGGA---ISKPLTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPL 2615
Query: 820 KSDHYTIQRDLDG-TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
++ I+ + DG L A+ LDD G YT A + + +L V+AV +
Sbjct: 2616 TNN---IRSESDGHKRRLIIAATKLDDIGEYTYKVATSK----TSAKLKVEAVKIKKTLK 2668
Query: 879 R------------SPSGHPHVRRPR------------------------SRSRDSGDENE 902
HP+V+ + R ++ +E
Sbjct: 2669 NLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDE 2728
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL----DGKPV------- 951
+ FR L A L V+ K+ + V+ L +++++ D PV
Sbjct: 2729 SVYG--FRLGRLGASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSV 2786
Query: 952 --RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP 1009
+P H+ LV E VH L+++ ++ DAG YT + GQ +L V K
Sbjct: 2787 EIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVETLHITK- 2840
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
++N V + EC V P ++ K E ++ + H L
Sbjct: 2841 -----TMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQ---L 2892
Query: 1070 LIQGATKEDAGWYTVSAKNE 1089
+I + ED+ YT N+
Sbjct: 2893 IIMNTSTEDSAEYTFVCGND 2912
Score = 44.7 bits (104), Expect = 5e-04
Identities = 80/363 (22%), Positives = 132/363 (36%), Gaps = 54/363 (14%)
Query: 263 SALHFPAAPRFIQKLRSQE---VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
S+ H PR I LR + V G +C ++ P V W+ +GK+L + +
Sbjct: 5880 SSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVP 5938
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI-EGASSTDSDSESLAFKS 378
EG +HTL + + +D G A + T A +F+ E E +
Sbjct: 5939 RSEG-KVHTLTLRDVKLEDAGEVQLTAKDFK----THANLFVKEPPVEFTKPLEDQTVEE 5993
Query: 379 RAGAMPQAQKKTTSVSLT-------IGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRP 431
A A+ + + + + I S V ++ L + +Y C
Sbjct: 5994 GATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 6053
Query: 432 DGTTTA----YFPP--VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSP 485
T+ PP F + L + V E ++ EC + +V+WF+ G+EI+
Sbjct: 6054 KDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGK 6112
Query: 486 DFRILQK---------KPRSTAEPEEICTLVIAE-----TFPEDAGIFTCSARNDYGSAT 531
+ I+ K K E E C + A T E+ +FT + N S T
Sbjct: 6113 KYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANIEVSET 6172
Query: 532 STAQLV--VTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNN 589
T +LV V+ E Y+ E I+ET E+ ++ I + N
Sbjct: 6173 DTIKLVCEVSKPGAEVIWYKGDEE--------------IIETGRYEILTEGRKRILVIQN 6218
Query: 590 PEL 592
L
Sbjct: 6219 AHL 6221
Score = 44.7 bits (104), Expect = 5e-04
Identities = 53/200 (26%), Positives = 88/200 (44%), Gaps = 32/200 (16%)
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH 886
++D D +HT A+ + + +T+ P ++ V AVN +G S S
Sbjct: 23077 EKDTDQWYRVHTNATIRNTE--FTV----PDLKMGQKYSFRVAAVNVKGMSEYS------ 23124
Query: 887 VRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL----TVQEGKLCRMDCKVSGLPTPDL 942
+S E EP+ ER P L+ DL T++ G R+ VSG P P +
Sbjct: 23125 ---------ESIAEIEPV-ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVI 23173
Query: 943 SWQLDGKPVRPDSAHKMLVRENGVHSL-IIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+W G D A + ++ +SL I++ V DAG YT A N++G+ S ++ + V
Sbjct: 23174 TWSKQGI----DLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23229
Query: 1002 AAKEAHKPPVFIEKLQNTGV 1021
P V ++++ V
Sbjct: 23230 YDTPGPCPSVKVKEVSRDSV 23249
Score = 44.3 bits (103), Expect = 6e-04
Identities = 36/106 (33%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNT--GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTD 1055
E V+A H P V ++ V G +R+ RV G P P I W KE + L
Sbjct: 11590 ESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE-K 11648
Query: 1056 RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
RV + QD + L I+ A + D G Y +SAKN +G +A ++V
Sbjct: 11649 RVDLIQD-LPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNV 11693
Score = 44.3 bits (103), Expect = 6e-04
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G + ++ V G P PRV WF +G E+ +++I G +L + +A D G
Sbjct: 21665 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST-SLFVRDATRDHRGV 21723
Query: 342 YTCLATNPSGSDTTSAEVFIE 362
YT A N SGS +V ++
Sbjct: 21724 YTVEAKNASGSAKAEIKVKVQ 21744
Score = 43.9 bits (102), Expect = 8e-04
Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG--VADGYPVRLECRVLGVPPPQIFW 1043
A N G+ + S VVA + P + ++ L + + RL+ + G P P + W
Sbjct: 13652 AENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13711
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
KK + L T RVS+ + + L++ K DAG YT++ KN AG T + V
Sbjct: 13712 KKGEDPLATDT-RVSV-ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13767
Score = 43.9 bits (102), Expect = 8e-04
Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 8/136 (5%)
Query: 744 LISEIEYRLERSPVDESG-DEVQYGDVPV---ENGMAPFFEMKLKHYKIFEGMPVTFTCR 799
L S EY+ +E G + + VPV + + P ++ Y I G +
Sbjct: 17970 LSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIP 18029
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGR 859
V G P+P I W KDG+ + ++ ++ T LH DD G YT+ A N G
Sbjct: 18030 VIGRPRPNISWVKDGEPLK-QTTRVNVEETATSTV-LHIKEGNKDDFGKYTVTATNSAG- 18086
Query: 860 ISCTGRLMVQAVNQRG 875
+ T L V + + G
Sbjct: 18087 -TATENLSVIVLEKPG 18101
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
L V+ G R + G+P P W DG ++ D H + +N L I+ RD
Sbjct: 11215 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDT 11273
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y +N AG + ++ L V
Sbjct: 11274 GEYQITVSNAAGSKTVAVHLTV 11295
Score = 43.5 bits (101), Expect = 0.001
Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSD-HYTIQRDLDGTCSLHTTASTLDDDGNY 849
G V V G P P + W KDG + P +QR+L C+L + D G+Y
Sbjct: 13005 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL---CTLELFSVNRKDSGDY 13061
Query: 850 TIMAANPQGRISCTGRLMV 868
TI A N G S T +L V
Sbjct: 13062 TITAENSSGSKSATIKLKV 13080
Score = 43.5 bits (101), Expect = 0.001
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
++ G+ R++ VSG P P + W DGK + + ++ + + +L+ + T RD+G
Sbjct: 15168 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15226
Query: 982 YTCIATNRAG 991
YT ATN G
Sbjct: 15227 YTLTATNPGG 15236
Score = 43.1 bits (100), Expect = 0.001
Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 18/145 (12%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V AVN++GRS P V + + P A +VQ G+
Sbjct: 16898 VVAVNEKGRSDPRSLAVPIVAK----------------DLVIEPDVKPAFSSYSVQVGQD 16941
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIAT 987
+++ +SG P P ++W DG P++ + + + +L I+ D G Y
Sbjct: 16942 LKIEVPISGRPKPTITWTKDGLPLK-QTTRINVTDSLDLTTLSIKETHKDDGGQYGITVA 17000
Query: 988 NRAGQNSFSLELVVAAK-EAHKPPV 1011
N GQ + S+E+V K + K PV
Sbjct: 17001 NVVGQKTASIEIVTLDKPDPPKGPV 17025
Score = 42.7 bits (99), Expect = 0.002
Identities = 59/256 (23%), Positives = 100/256 (39%), Gaps = 28/256 (10%)
Query: 277 LRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE 336
L Q VAE EC V NP + W +GK L T +I+ + G LIIA
Sbjct: 2580 LTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPLTNNIRSESD-GHKRRLIIAATKL 2637
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGA-------SSTDSDSESLAFKSRAGAMPQAQKK 389
DD G YT + TSA++ +E + T ++++ F P +
Sbjct: 2638 DDIGEYTYKV----ATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL-THPNVKGV 2692
Query: 390 TTSVSLTIGSSSPKTGVTT-AVIQPLSVPVQQVHSPTSY---LCRPDGTTTAYFPPV-FT 444
+ + S+ K ++ I L + + + Y L R + + V
Sbjct: 2693 QWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKII 2752
Query: 445 KELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
K+ ++ E V E V + V+WF + EI+ S R++ ++ ++
Sbjct: 2753 KKPKDVTALENATVAFEVSV-SHDTVPVKWFHKSVEIKPSDKHRLVSER--------KVH 2803
Query: 505 TLVIAETFPEDAGIFT 520
L++ P DAG +T
Sbjct: 2804 KLMLQNISPSDAGEYT 2819
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG---VADGYPVRLECRVLGVPPPQIF 1042
A N AG+ V E +PP + G + G +R+ V G P P
Sbjct: 8773 AVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8832
Query: 1043 WKKENESLTHSTDRVSMHQDNHGYIC-LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
W KE L DRV + DN G L+I+ A ++D G Y ++A N G AR++V
Sbjct: 8833 WTKEEGEL--DKDRVVI--DNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8888
Query: 1102 Y 1102
+
Sbjct: 8889 F 8889
Score = 42.7 bits (99), Expect = 0.002
Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELV--VAAKEAHKPPVFIEKLQNTGVAD---G 1024
II +T + A N G S E+V + +++ PV L+ T V G
Sbjct: 20523 IISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAG 20582
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
V+L + G P P I W K+++ L T+ + ++ +LI+ A + ++G Y +
Sbjct: 20583 TSVKLRAGISGKPAPTIEWYKDDKEL--QTNALVCVENTTDLASILIKDADRLNSGCYEL 20640
Query: 1085 SAKNEAGIVSCTARLDV 1101
+N G S T R+ +
Sbjct: 20641 KLRNAMGSASATIRVQI 20657
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
I G + V G P P++ WFKDG +I + + D+ G+ SL +T D G
Sbjct: 21665 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI--TDVLGSTSLFVRDATRDHRG 21722
Query: 848 NYTIMAANPQGRISCTGRLMVQ 869
YT+ A N G ++ VQ
Sbjct: 21723 VYTVEAKNASGSAKAEIKVKVQ 21744
Score = 42.4 bits (98), Expect = 0.002
Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 11/105 (10%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G ++ +E V G P P +W E+ + + +H + LII + D+G
Sbjct: 12605 IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVH-KADSSSILIIKDVTRKDSGY 12663
Query: 342 YTCLATNPSGSDTTSAEVFIEGA----------SSTDSDSESLAF 376
Y+ A N SG+DT +V + A S D+D+ SL++
Sbjct: 12664 YSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSW 12708
Score = 42.0 bits (97), Expect = 0.003
Identities = 41/146 (28%), Positives = 60/146 (41%), Gaps = 19/146 (13%)
Query: 402 PKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAY----FPPVFTKELQNTAVAEGQV 457
P GV P+ +++ + PD Y P F KE+++ + E +
Sbjct: 4767 PIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEF 4826
Query: 458 V----VLECRVRGAPPLQVQWFRQGSEIQDSPDFR-ILQKKPRSTAEPEEICTLVIAETF 512
V + EC V + + W + GS I++SP R I K R L I +
Sbjct: 4827 VGSSAIFECLVSPSTAITT-WMKDGSNIRESPKHRFIADGKDRK---------LHIIDVQ 4876
Query: 513 PEDAGIFTCSARNDYGSATSTAQLVV 538
DAG +TC R TSTA+LVV
Sbjct: 4877 LSDAGEYTCVLRLGNKEKTSTAKLVV 4902
Score = 42.0 bits (97), Expect = 0.003
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A P F KL + E + L+C V+ + V+WF +G+E+ +P I + G
Sbjct: 5356 ADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSPKYSIKAD-GLRRI 5412
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
L I +A D G Y C G+D T A V +E
Sbjct: 5413 LKIKKADLKDKGEYVC----DCGTDKTKANVTVE 5442
Score = 42.0 bits (97), Expect = 0.003
Identities = 61/251 (24%), Positives = 94/251 (37%), Gaps = 50/251 (19%)
Query: 783 LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 842
LK ++ E V F C V K WF++ + I S + +Q+DL +L +
Sbjct: 6341 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDL--VYTLRIRDAH 6397
Query: 843 LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENE 902
LDD NY V N RG + +S + N
Sbjct: 6398 LDDQANYN-----------------VSLTNHRGENVKSAA------------------NL 6422
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
++E R ++ D+ E K CKV+ L L W +G+ V D+ V
Sbjct: 6423 IVEEEDLR--IVEPLKDIETMEKKSVTFWCKVNRL-NVTLKWTKNGEEVPFDNRVSYRV- 6478
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVA 1022
+ H L I+ D G Y I T AGQ+ EL++ P F+E L++ V
Sbjct: 6479 DKYKHMLTIKDCGFPDEGEY--IVT--AGQDKSVAELLI----IEAPTEFVEHLEDQTVT 6530
Query: 1023 DGYPVRLECRV 1033
+ C++
Sbjct: 6531 EFDDAVFSCQL 6541
Score = 42.0 bits (97), Expect = 0.003
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFED 337
R Q + G + L + G P P+V W E ++ I + G L I A +
Sbjct: 10921 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLE---IRNAAHE 10977
Query: 338 DTGRYTCLATNPSGSDTTSAEVFI 361
D G Y+ NP+GS T S +V +
Sbjct: 10978 DGGIYSLTVENPAGSKTVSVKVLV 11001
Score = 42.0 bits (97), Expect = 0.003
Identities = 42/170 (24%), Positives = 73/170 (42%), Gaps = 13/170 (7%)
Query: 939 TPDLSWQLDGKPVRPDS---AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSF 995
+P+LS+ ++ + D HK ++E +++ + N G++ +
Sbjct: 11825 SPNLSYHVERRLKGSDDWERVHKGSIKET---HYMVDRCVENQIYEFRVQTKNEGGESDW 11881
Query: 996 SLELVVAAKEAHKPPVFIEKLQNT-GVADGYPVRLECRVLGVPPPQIFWKKENES--LTH 1052
V KE + PV KL V G +RLE V G P P++ W K+ ++ LT
Sbjct: 11882 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11941
Query: 1053 STD-RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
S ++ D+ + + A + D G Y V+A N AG A ++V
Sbjct: 11942 SPRVKIDTRADSSKF---SLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNS-FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
+I +T + ++ +A N G++ SL + + AK+ P + V G ++
Sbjct: 16884 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 16943
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
+E + G P P I W K+ L +T R+++ D+ L I+ K+D G Y ++ N
Sbjct: 16944 IEVPISGRPKPTITWTKDGLPLKQTT-RINV-TDSLDLTTLSIKETHKDDGGQYGITVAN 17001
Query: 1089 EAG 1091
G
Sbjct: 17002 VVG 17004
Score = 41.6 bits (96), Expect = 0.004
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSR- 977
D+ V EG+ + +P P +SW DGK V+ ++ ++ ++ + + + + P + R
Sbjct: 8090 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK--ASDRLTMKNDHISAHLEVPKSVRA 8147
Query: 978 DAGIYTCIATNRAGQNSFSLELVV 1001
DAGIYT N+ G + S+ + V
Sbjct: 8148 DAGIYTITLENKLGSATASINVKV 8171
Score = 41.6 bits (96), Expect = 0.004
Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
P + KE V EG V + +++G P + WF+ + D+ + +L +
Sbjct: 9813 PSIDLKEFME--VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLV 9869
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ CTLVI ++ D G++T +A N+ G+A+ +L V
Sbjct: 9870 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9908
Score = 41.6 bits (96), Expect = 0.004
Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 12/100 (12%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE------- 972
+ V+EG + K+ G+P P L+W P +PD+ +L + V+ L+++
Sbjct: 9821 MEVEEGTNVNIVAKIKGVPFPTLTW-FKAPPKKPDNKEPVLY-DTHVNKLVVDDTCTLVI 9878
Query: 973 PVTSR-DAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV 1011
P + R D G+YT A N G S + L V + PPV
Sbjct: 9879 PQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPG--PPV 9916
Score = 41.6 bits (96), Expect = 0.004
Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 4/82 (4%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL-IQGATKEDA 1079
V G V L+ V G P P + WKK+ +L + + M + +C L + ++D+
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRN--LCTLELFSVNRKDS 13058
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G YT++A+N +G S T +L V
Sbjct: 13059 GDYTITAENSSGSKSATIKLKV 13080
Score = 41.2 bits (95), Expect = 0.005
Identities = 35/149 (23%), Positives = 64/149 (42%), Gaps = 17/149 (11%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V AVN++GRS G P + R E +P E F ++A L
Sbjct: 19063 VAAVNEKGRSDPRQLGVPVIAR--------DIEIKPSVELPFHTFNVKAREQL------- 19107
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIAT 987
++D G P ++W+ DG+ ++ ++ + V SL I+ + D G Y +
Sbjct: 19108 -KIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 19165
Query: 988 NRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
N AG + + ++V + P+ I+++
Sbjct: 19166 NSAGSITVPITIIVLDRPGPPGPIRIDEV 19194
Score = 41.2 bits (95), Expect = 0.005
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
Query: 1000 VVAAKEAHKPPVFI---EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDR 1056
++ ++ + PP+ E + G +R++ V G P P++ W K+ + R
Sbjct: 21641 IIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEK---R 21697
Query: 1057 VSMH-QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
++M D G L ++ AT++ G YTV AKN +G ++ V
Sbjct: 21698 MNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21743
Score = 41.2 bits (95), Expect = 0.005
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
GS ++ ++G P P+V W E L T + I D TL + ++ D+GRY
Sbjct: 22357 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYFL 22415
Query: 345 LATNPSGSDTTSAEVFIEG 363
N +G T S V + G
Sbjct: 22416 TLENTAGVKTFSVTVVVIG 22434
Score = 40.8 bits (94), Expect = 0.007
Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 20/205 (9%)
Query: 678 DAVIQDLERK---LRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQE 734
D + D RK + +K N G P + Y M +G + N + ++ +
Sbjct: 7985 DLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP--VGTEKWMRVNSRPIKD----LK 8038
Query: 735 YKVSSCEQRLISEIEYRLERSPVDESG----DEVQYGDVPVENGMAPFFEMKLKHYKIFE 790
+KV E+ ++ + EY L V+ G E+ V + P +++ + E
Sbjct: 8039 FKV---EEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIE 8095
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G ++ P P + W KDGK++ SD T++ D + L S D G YT
Sbjct: 8096 GEKLSIPVPFRAVPVPTVSWHKDGKEVK-ASDRLTMKND-HISAHLEVPKSVRADAGIYT 8153
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
I N G S T + V+ + G
Sbjct: 8154 ITLENKLG--SATASINVKVIGLPG 8176
Score = 40.8 bits (94), Expect = 0.007
Identities = 32/106 (30%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRV 1057
E VVA KP + +E + V +G + + VP P + W K+ + + S DR+
Sbjct: 8071 ENVVAKDPDCKPTIDLET-HDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKAS-DRL 8128
Query: 1058 SMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
+M D H L + + + DAG YT++ +N+ G S TA ++V +
Sbjct: 8129 TMKND-HISAHLEVPKSVRADAGIYTITLENKLG--SATASINVKV 8171
Score = 40.8 bits (94), Expect = 0.007
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P E + V EG+ + + R P V W + G E++ S R+ K +A
Sbjct: 8082 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD--RLTMKNDHISAH- 8138
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L + ++ DAGI+T + N GSAT++ + V
Sbjct: 8139 -----LEVPKSVRADAGIYTITLENKLGSATASINVKV 8171
Score = 40.8 bits (94), Expect = 0.007
Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 8/100 (8%)
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFK------DGKQISPKSDHYTIQR 828
M P ++K + ++ EG V ++ G P P + WFK D K+ H +
Sbjct: 9811 MPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KL 9868
Query: 829 DLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
+D TC+L S D G YTI A N G S RL V
Sbjct: 9869 VVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9908
Score = 40.4 bits (93), Expect = 0.009
Identities = 52/218 (23%), Positives = 83/218 (38%), Gaps = 51/218 (23%)
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
+GG T + EA + T R+ + T +E ++ ++ E F+ RA
Sbjct: 23356 DGGSRLTGYVLEACKAGTERWMKVVT--------LKPTVLEHTVTSLNEGEQYLFRIRA- 23406
Query: 382 AMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP 441
Q +K G S P+ VT +Q L V PT L
Sbjct: 23407 ---QNEK---------GVSEPRETVTAVTVQDLRV------LPTIDLS------------ 23436
Query: 442 VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
T + V G+ V L + G PP WF GS++++S R T E
Sbjct: 23437 --TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRES---------ERVTVETH 23485
Query: 502 -EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ L I ET D G +T +N G+ + T ++++
Sbjct: 23486 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVII 23523
Score = 40.0 bits (92), Expect = 0.012
Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G T R +G PKPK+ WFKD + D T + T +L + D G Y
Sbjct: 10528 GEAFALTGRYSGKPKPKVSWFKDEADV--LEDDRTHIKTTPATLALEKIKAKRSDSGKYC 10585
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
++ N G S G V V++ G
Sbjct: 10586 VVVENSTG--SRKGFCQVNVVDRPG 10608
Score = 39.7 bits (91), Expect = 0.016
Identities = 74/339 (21%), Positives = 122/339 (35%), Gaps = 77/339 (22%)
Query: 758 DESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQI 817
D+S E+ + P E F L+ + E F+C+++ K + W+++G++I
Sbjct: 6505 DKSVAELLIIEAPTE------FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNGREI 6557
Query: 818 SPKSDHYTIQRDLDGTCSLHTTA---STLDDDGNYTIMAANPQGRISCTGRLMVQAVNQR 874
+ Y ++D S+H LDD+ Y + + R RL V+ +
Sbjct: 6558 K-EGKKYKFEKD----GSIHRLIIKDCRLDDECEYACGVEDRKSR----ARLFVEEI--- 6605
Query: 875 GRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRP--HFLQAPGDLTVQEGKLCRMDC 932
P++ RP L+APG V +L +
Sbjct: 6606 ----------------------------PVE--IIRPPQDILEAPGADVVFLAELNKDKV 6635
Query: 933 KVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQ 992
+V W + V H+M+ E +H L I + RD G Y IA ++ +
Sbjct: 6636 EVQ--------WLRNNMVVVQGDKHQMM-SEGKIHRLQICDIKPRDQGEYRFIAKDKEAR 6686
Query: 993 NSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTH 1052
L K A Q+ V G P+ + P + W KENE L+
Sbjct: 6687 AKLELAAAPKIKTAD---------QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLST 6737
Query: 1053 STDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
T + Q + I A K D G Y + +N+ G
Sbjct: 6738 KTIDTTAEQTS-----FRILEAKKGDKGRYKIVLQNKHG 6771
Score = 39.7 bits (91), Expect = 0.016
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
++ G + + VTG P P W E EL D + G LII +A D G
Sbjct: 8810 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDK--DRVVIDNVGTKSELIIKDALRKDHG 8867
Query: 341 RYTCLATNPSGSDTTSAEV 359
RY ATN GS +A V
Sbjct: 8868 RYVITATNSCGSKFAAARV 8886
Score = 39.7 bits (91), Expect = 0.016
Identities = 41/146 (28%), Positives = 60/146 (41%), Gaps = 24/146 (16%)
Query: 865 RLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQE 924
R V+AVN+ G S P + D +E E + + A L +
Sbjct: 9473 RFRVKAVNEAGES------EPSDTTGEIPATDIQEEPEVFID-------IGAQDCLVCKA 9519
Query: 925 GKLCRMDCKVSGLPTPDLSWQLDGKPVR--PDSAH------KMLVRENGVHSLIIEPVTS 976
G R+ + G PTP SW+ DGK + D H ++ EN S+II P
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENS--SVIIIPECK 9577
Query: 977 RD-AGIYTCIATNRAGQNSFSLELVV 1001
R G Y+ A N+AGQ + + + V
Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKV 9603
Score = 39.7 bits (91), Expect = 0.016
Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 9/138 (6%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF-----IEKLQNTGVADG 1024
++ +T + + +A N AG+++ V KE P +KL D
Sbjct: 14718 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDN 14777
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
+++E VLG P P + WKK + + T RV+ I L I + D+G Y +
Sbjct: 14778 --IKVEIPVLGRPKPTVTWKK-GDQILKQTQRVNFETTATSTI-LNINECVRSDSGPYPL 14833
Query: 1085 SAKNEAGIVSCTARLDVY 1102
+A+N G V + V+
Sbjct: 14834 TARNIVGEVGDVITIQVH 14851
Score = 39.7 bits (91), Expect = 0.016
Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 7/125 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P + ++ K ++T V G +++ + G
Sbjct: 16206 FRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGK 16265
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
P P I W K ++ L++ T R+ + + L ++ A + D+G Y + AKN AG S T
Sbjct: 16266 PIPTIQWIKGDQELSN-TARLEIKSTDFA-TSLSVKDAVRVDSGNYILKAKNVAGERSVT 16323
Query: 1097 ARLDV 1101
+ V
Sbjct: 16324 VNVKV 16328
Score = 39.3 bits (90), Expect = 0.021
Identities = 42/174 (24%), Positives = 69/174 (39%), Gaps = 12/174 (6%)
Query: 688 LRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISE 747
L+++ + G P L+Y + RRL G+D + +E Y V C + I
Sbjct: 11814 LKWRRPDYDGGSPNLSYH--VERRLKGSDDWERVHKGSIKET----HYMVDRCVENQI-- 11865
Query: 748 IEYRLERSPVDESGDEVQYGDVPVENGMA-PFFEMKLKHY-KIFEGMPVTFTCRVAGNPK 805
E+R++ D V+ +V V+ + P ++KL + G + V G P
Sbjct: 11866 YEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPF 11925
Query: 806 PKIYWFKDGKQIS-PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQG 858
P++ W KD +S I D + T + D G Y + A N G
Sbjct: 11926 PEVAWTKDKDATDLTRSPRVKIDTRADSS-KFSLTKAKRSDGGKYVVTATNTAG 11978
Score = 39.3 bits (90), Expect = 0.021
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI-IEPVTSRD 978
+ V+ G++ +++ ++G P P +SW DG + + +++ +N H+L+ ++ RD
Sbjct: 19494 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN--HTLLTVKDCIRRD 19551
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAK 1004
G Y N AG S ++ V K
Sbjct: 19552 TGQYVLTLKNVAGTRSVAVNCKVLDK 19577
Score = 38.9 bits (89), Expect = 0.027
Identities = 63/282 (22%), Positives = 102/282 (36%), Gaps = 24/282 (8%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
I L+ V EG++ LEC+V+ V+W+ +++ +Q + G L+I
Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK-GTKQRLVINR 2460
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASS-TDSDSESLAFK---SRAGAMPQAQ 387
D G Y + + S E I G T ++++++ F+ S +G
Sbjct: 2461 THASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWN 2520
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPV----F 443
K + SS I L+V Y T+ V
Sbjct: 2521 FKDKEIK----PSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAI 2576
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
+K L + VAE Q V EC V P + +W R G + L RS ++ +
Sbjct: 2577 SKPLTDQTVAESQEAVFECEVAN-PDSKGEWLRDGKHLP-------LTNNIRSESDGHK- 2627
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTEN 545
L+IA T +D G +T SA + V +N
Sbjct: 2628 RRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKN 2669
Score = 38.9 bits (89), Expect = 0.027
Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 10/104 (9%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWF------CEGKE--LHNTPDIQI 319
P P I EV EG+ V + ++ G P P + WF + KE L++T ++
Sbjct: 9809 PDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKL 9868
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
+ D TL+I ++ DTG YT A N G+ + + + G
Sbjct: 9869 VVD--DTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9910
Score = 38.9 bits (89), Expect = 0.027
Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 22/125 (17%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V GQ + + RV+G P + W ++G + ++Q PR L I E
Sbjct: 11615 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPR--------VELQIKEA 11666
Query: 512 FPEDAGIFTCSARNDYGSATSTA------------QLVVTSANTENC--SYESMGESNND 557
D G + SA+N G A +A L VT+ ENC S+E+ ++
Sbjct: 11667 VRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGS 11726
Query: 558 HFQHF 562
+F
Sbjct: 11727 EITNF 11731
Score = 38.9 bits (89), Expect = 0.027
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F TV G+ ++D G PTP ++W D P++ + EN L
Sbjct: 15843 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN-SLLT 15901
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
I+ D G Y TN AG+ +L ++V K
Sbjct: 15902 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15935
Score = 38.9 bits (89), Expect = 0.027
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 768 DVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ 827
D+ +E + P F Y + G + ++G PKP I W KDG + ++ +
Sbjct: 16920 DLVIEPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINVT 16974
Query: 828 RDLDGTCSLHTTASTLDDDGNYTIMAANPQGR 859
LD T +L + DD G Y I AN G+
Sbjct: 16975 DSLDLT-TLSIKETHKDDGGQYGITVANVVGQ 17005
Score = 38.9 bits (89), Expect = 0.027
Identities = 35/139 (25%), Positives = 50/139 (35%), Gaps = 24/139 (17%)
Query: 227 QGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGS 286
+ + E+ V P QDL V P +H PA G
Sbjct: 23405 RAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPA---------------GR 23449
Query: 287 RVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT----LIIAEAFEDDTGRY 342
V L + G P P WF G +L + + + + HT L I E DTG Y
Sbjct: 23450 PVELVIPIAGRPPPAASWFFAGSKLRESERVTV-----ETHTKVAKLTIRETTIRDTGEY 23504
Query: 343 TCLATNPSGSDTTSAEVFI 361
T N +G+ + + +V I
Sbjct: 23505 TLELKNVTGTTSETIKVII 23523
Score = 38.5 bits (88), Expect = 0.036
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKE-------LHNTPDIQIHCEGGDLHTLIIAEAFED 337
GS++ + + G PTP+ W +GK +H+ P+ + +II E
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9579
Query: 338 DTGRYTCLATNPSGSDTTSAEV 359
TG+Y+ A N +G T + V
Sbjct: 9580 HTGKYSITAKNKAGQKTANCRV 9601
Score = 38.5 bits (88), Expect = 0.036
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 13/129 (10%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLE---LVVAAKEAHKPPVFIE-KLQNTGVAD-GY 1025
+ +T A + IA N AG S E + + P + ++ K ++T + G
Sbjct: 15113 VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGE 15172
Query: 1026 PVRLECRVLGVPPPQIFWKKENESLTHSTD---RVSMHQDNHGYICLLIQGATKEDAGWY 1082
RLE V G PPP + W K+ + L + +++ N L+ + +T+ D+G Y
Sbjct: 15173 AFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN-----LVNKDSTRRDSGAY 15227
Query: 1083 TVSAKNEAG 1091
T++A N G
Sbjct: 15228 TLTATNPGG 15236
Score = 38.5 bits (88), Expect = 0.036
Identities = 37/159 (23%), Positives = 65/159 (40%), Gaps = 18/159 (11%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V G+ + ++G P P SW G +R +S + V L I T RD G
Sbjct: 23445 VPAGRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTVETHTKVAKLTIRETTIRDTGE 23503
Query: 982 YTCIATNRAGQNSFSLELVVAAKEAHKP-PVFIEKLQNTGVADGY-PVRLECRVLGVPPP 1039
YT N G S ++++++ K P+ I+++ T + + P L+ G P
Sbjct: 23504 YTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPL 23559
Query: 1040 QIF-----------WKKENESLTHSTDRVSMHQDNHGYI 1067
+ W +ES+T ST + + + + Y+
Sbjct: 23560 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYV 23598
Score = 38.1 bits (87), Expect = 0.046
Identities = 59/300 (19%), Positives = 106/300 (35%), Gaps = 48/300 (16%)
Query: 79 PSHKETKLGEHASRRPQDNRSTPVQPLAEKQTKSISSPVSKRKPAMSPL--LTRPSYIRS 136
P KE + + R+ + V+P K+ + + P P P+ + P+ +
Sbjct: 4636 PEPKEEVVLKSVLRKRPEEEEPKVEP---KKLEKVKKPAVPEPPPPKPVEEVEVPTVTKR 4692
Query: 137 LRKAE--------KRGAKTPSTNVKPKTPHQRKGGPQSQLCDKAANLIEELTSIFKAAKP 188
RK K P+ KPK + K + + + +T K
Sbjct: 4693 ERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKA 4752
Query: 189 RNRSPNGESSSPDSGYLS-PKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQ 247
++P E++ P PK PS + E ER PG+
Sbjct: 4753 EAKAPKEEAAKPKGPIKGVPKKTPSPI--------------EAERRKLRPGSG------- 4791
Query: 248 DLAVPHNRKSHPQPHSALHFPAAP-RFIQKLRSQEVAE----GSRVYLECRVTGNPTPRV 302
K + A P +F+++++ + E GS EC V+ + T
Sbjct: 4792 ------GEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPS-TAIT 4844
Query: 303 RWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
W +G + +P + +G D L I + D G YTC+ + T++A++ +E
Sbjct: 4845 TWMKDGSNIRESPKHRFIADGKD-RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 4903
Score = 38.1 bits (87), Expect = 0.046
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 8/114 (7%)
Query: 982 YTCIATNRAGQNSFS-LELVVAAKEAHKPPVFI---EKLQNTGVADGYPVRLECRVLGVP 1037
+ +A N AG++ + + V K+ +PP I + + G +RL + GVP
Sbjct: 10882 FRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVP 10941
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
P++ WKKE+ + R+ + L I+ A ED G Y+++ +N AG
Sbjct: 10942 FPKVTWKKEDRD-APTKARIDVTPVGSK---LEIRNAAHEDGGIYSLTVENPAG 10991
Score = 38.1 bits (87), Expect = 0.046
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G+ V L+ V G P P V W +G L I++ + +L TL + D+G
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQ-RNLCTLELFSVNRKDSGD 13060
Query: 342 YTCLATNPSGSDTTSAEV 359
YT A N SGS + + ++
Sbjct: 13061 YTITAENSSGSKSATIKL 13078
Score = 38.1 bits (87), Expect = 0.046
Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Query: 920 LTVQEGKLCRMDC-KVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
LT++ G ++ + G P P SW GK +RP ++ L I+ T +D
Sbjct: 14083 LTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKD 14141
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
AG YT ATN G +++ V PV I +
Sbjct: 14142 AGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNV 14179
Score = 38.1 bits (87), Expect = 0.046
Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ GS + L+ V G P P++ W KEL + + G T +I D+G+
Sbjct: 22754 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYT-GKRATAVIKFCDRSDSGK 22812
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SG+ S V
Sbjct: 22813 YTLTVKNASGTKAVSVMV 22830
Score = 37.7 bits (86), Expect = 0.061
Identities = 50/218 (22%), Positives = 81/218 (37%), Gaps = 46/218 (21%)
Query: 783 LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 842
L K+ EG V +V+ + W KDG+++ P SD I D L T
Sbjct: 2316 LSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQP-SDRVHIVIDKQSHMLL-IEDMT 2372
Query: 843 LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENE 902
+D GNY+ P +S +GR+ V +V D
Sbjct: 2373 KEDAGNYSFTI--PALGLSTSGRVSVYSV---------------------------DVIT 2403
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
P++ D+ V EG ++CKVS + W L+ + ++PD + +V+
Sbjct: 2404 PLK-------------DVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK 2450
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 1000
L+I + D G Y I + S+E +
Sbjct: 2451 -GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKI 2487
Score = 37.7 bits (86), Expect = 0.061
Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 8/87 (9%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G V L+ V G P V W + G+ ++ + ++ ++ +CTL +
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR--------NLCTLELFSV 13053
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVV 538
+D+G +T +A N GS ++T +L V
Sbjct: 13054 NRKDSGDYTITAENSSGSKSATIKLKV 13080
Score = 37.4 bits (85), Expect = 0.079
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWF--CEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDT 339
V G + LE V G P P V W + +L +P ++I D + +A D
Sbjct: 11908 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTR-ADSSKFSLTKAKRSDG 11966
Query: 340 GRYTCLATNPSGSDTTSAEV 359
G+Y ATN +GS A V
Sbjct: 11967 GKYVVTATNTAGSFVAYATV 11986
Score = 37.0 bits (84), Expect = 0.10
Identities = 47/218 (21%), Positives = 90/218 (41%), Gaps = 34/218 (15%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G+ V + V G P +++W + + I+ D + K+ S +E + L I +
Sbjct: 9105 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAK--TELSIPKA 9162
Query: 512 FPEDAGIFTCSARNDYGSA------------TSTAQLVVTSANTENC--SYESMGESNND 557
ED G +T +A N GS + L VT E+C ++++ ++
Sbjct: 9163 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGS 9222
Query: 558 HFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSR 617
H+ +++ AS+K +E ++V N A++ ++ + NG + R
Sbjct: 9223 EITHY-----VIDKRD---ASRKKAEWEEVTN-------TAVEKRYGIWKLIPNGQYEFR 9267
Query: 618 GVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKL 655
+N S++ V+ P + P P KPK+
Sbjct: 9268 --VRAVNKYGISDECKSDKVVIQDPYRLPGP-PGKPKV 9302
Score = 37.0 bits (84), Expect = 0.10
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL-IQGATKEDAGWY 1082
G +RL V G PPP+I W K N +L DR+ + + + L + K DAG Y
Sbjct: 13403 GVTMRLYVPVKGRPPPKITWSKPNVNL---RDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13459
Query: 1083 TVSAKNEAG 1091
++ +N G
Sbjct: 13460 ILTLENSCG 13468
Score = 37.0 bits (84), Expect = 0.10
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 923 QEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH-SLIIEPVTSRDAGI 981
+E R+ + G P P +SW+ P+ D+ ++ V + V+ +LI+ DAG
Sbjct: 13690 KENSNFRLKIPIKGKPAPSVSWKKGEDPLATDT--RVSVESSAVNTTLIVYDCQKSDAGK 13747
Query: 982 YTCIATNRAGQNSFSLELVVAAK 1004
YT N AG ++ + V K
Sbjct: 13748 YTITLKNVAGTKEGTISIKVVGK 13770
Score = 37.0 bits (84), Expect = 0.10
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQG 858
V+G P P + W KDGK++ + + D + +L ST D G YT+ A NP G
Sbjct: 15180 VSGRPPPTMEWSKDGKELEGTAKLEI--KIADFSTNLVNKDSTRRDSGAYTLTATNPGG 15236
Score = 37.0 bits (84), Expect = 0.10
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 10/121 (8%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ R++ V G P P + W K + +SA + + LI++ D
Sbjct: 17330 IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIE-ESARCEIKNTDFKALLIVKDAIRIDG 17388
Query: 980 GIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPP 1039
G Y A+N AG SF + + V + PP +Q TGV +C + PP
Sbjct: 17389 GQYILRASNVAGSKSFPVNVKVLDRPG--PPE--GPVQVTGVTSE-----KCSLTWSPPL 17439
Query: 1040 Q 1040
Q
Sbjct: 17440 Q 17440
Score = 37.0 bits (84), Expect = 0.10
Identities = 29/125 (23%), Positives = 57/125 (45%), Gaps = 3/125 (2%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNS-FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
I +T+ + ++ A N G++ L + V A++ P V +++
Sbjct: 19050 ISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKI 19109
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
+ G P + W+K+ ++L +T RV++ + L I+ A+KED G Y + N
Sbjct: 19110 DVPFKGRPQATVNWRKDGQTLKETT-RVNV-SSSKTVTSLSIKEASKEDVGTYELCVSNS 19167
Query: 1090 AGIVS 1094
AG ++
Sbjct: 19168 AGSIT 19172
Score = 37.0 bits (84), Expect = 0.10
Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 14/86 (16%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLT-----HSTDRVSMHQDNHGYICLLIQGAT 1075
V G +RL G P P W K + +L+ H+TD S L ++
Sbjct: 22064 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST---------LTVENCN 22114
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDV 1101
+ DAG YT++ +N +G S T + V
Sbjct: 22115 RNDAGKYTLTVENNSGSKSITFTVKV 22140
Score = 37.0 bits (84), Expect = 0.10
Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Query: 781 MKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA 840
M K + G PV +AG P P WF G ++ +S+ T++ L
Sbjct: 23438 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTVETHTK-VAKLTIRE 23495
Query: 841 STLDDDGNYTIMAANPQGRISCTGRLMV 868
+T+ D G YT+ N G S T ++++
Sbjct: 23496 TTIRDTGEYTLELKNVTGTTSETIKVII 23523
Score = 36.6 bits (83), Expect = 0.14
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 10/178 (5%)
Query: 193 PNGESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVP 252
P +SPD G+ N + L+ + + +++ E E V C Q+ + P
Sbjct: 12232 PKIADASPDEGW-KRCNAAAQLVRKEFTVTSLDENQEYEFRV-------CAQNQVGIGRP 12283
Query: 253 HNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELH 312
K +P L P + V G + L V G P P+V W G + +
Sbjct: 12284 AELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-N 12342
Query: 313 NTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSD 370
Q+ + L+I + DD+G+Y+ NP+G V + SD
Sbjct: 12343 VVRKGQVDLVD-TMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12399
Score = 36.6 bits (83), Expect = 0.14
Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P + ++ K ++T V + G RLE V G
Sbjct: 17288 FRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGK 17347
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
P P I W + ++ + S + D L+++ A + D G Y + A N AG S
Sbjct: 17348 PLPTIEWLRGDKEIEESARCEIKNTDFKA--LLIVKDAIRIDGGQYILRASNVAGSKSFP 17405
Query: 1097 ARLDV 1101
+ V
Sbjct: 17406 VNVKV 17410
Score = 36.6 bits (83), Expect = 0.14
Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
G+ V L ++G P P + W+ + KEL + + DL +++I +A ++G Y
Sbjct: 20582 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRLNSGCYEL 20640
Query: 345 LATNPSGSDTTSAEVFI 361
N GS + + V I
Sbjct: 20641 KLRNAMGSASATIRVQI 20657
Score = 36.6 bits (83), Expect = 0.14
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 5/103 (4%)
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHK 958
DEN P F +F L ++ G+ R+ V G P P ++W DG + +
Sbjct: 21646 DENVPPIVEFGPEYF----DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMNM 21700
Query: 959 MLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+ G SL + T G+YT A N +G +++ V
Sbjct: 21701 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21743
Score = 36.6 bits (83), Expect = 0.14
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC-LLIQGATKEDA 1079
V G PV L + G PPP W L S +RV++ + H + L I+ T D
Sbjct: 23445 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRES-ERVTV--ETHTKVAKLTIRETTIRDT 23501
Query: 1080 GWYTVSAKNEAGIVSCTARL 1099
G YT+ KN G S T ++
Sbjct: 23502 GEYTLELKNVTGTTSETIKV 23521
Score = 36.6 bits (83), Expect = 0.14
Identities = 20/97 (20%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V++G + R+ + G P P W +G+ + S M+ L+I+ D+G
Sbjct: 23843 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI---SKRAMIATSETHTELVIKEADRGDSGT 23899
Query: 982 YTCIATNRAGQNSFSLEL-VVAAKEAHKPPVFIEKLQ 1017
Y + N+ G+ + +++ V+ + + + P+ + +Q
Sbjct: 23900 YDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQ 23936
Score = 36.2 bits (82), Expect = 0.18
Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 6/80 (7%)
Query: 284 EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC-EGGDLHTLIIAEA-FEDDTGR 341
EG V+L +T V W+ E K + + D + C + + +TL+I + ED G
Sbjct: 4448 EGDIVHLTTSITN--AKEVNWYFENKLVPS--DEKFKCLQDQNTYTLVIDKVNTEDHQGE 4503
Query: 342 YTCLATNPSGSDTTSAEVFI 361
Y C A N SG TSA++ +
Sbjct: 4504 YVCEALNDSGKTATSAKLTV 4523
Score = 36.2 bits (82), Expect = 0.18
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 1/86 (1%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
++ L V G+++ L VTG P P++ W L I I T+ I +
Sbjct: 7389 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVD 7447
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAEV 359
+ DTG Y A N G T EV
Sbjct: 7448 SKRSDTGTYIIEAVNVCGRATAVVEV 7473
Score = 36.2 bits (82), Expect = 0.18
Identities = 39/169 (23%), Positives = 59/169 (34%), Gaps = 22/169 (13%)
Query: 824 YTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG 883
Y + + L GT + YT+ R +L V AVN G P +
Sbjct: 8731 YFVDKQLVGTNEWSRCTEKMIKVRQYTVKEI----REGADYKLRVSAVNAAGEGPPGETQ 8786
Query: 884 HPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLS 943
V P+ D + G + + GK R+ V+G P P
Sbjct: 8787 PVTVAEPQEPPAVELD--------------VSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8832
Query: 944 WQLDGKPVRPDSAHKMLVRENGVHS-LIIEPVTSRDAGIYTCIATNRAG 991
W + + D ++++ G S LII+ +D G Y ATN G
Sbjct: 8833 WTKEEGELDKD---RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8878
Score = 36.2 bits (82), Expect = 0.18
Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 9/123 (7%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKK 1045
A N AG + S + + P I+ + V +G V + ++ GVP P + W K
Sbjct: 9788 AVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 9847
Query: 1046 -------ENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTAR 1098
E + + T + D+ L+I + + D G YT++A N G S R
Sbjct: 9848 APPKKPDNKEPVLYDTHVNKLVVDDT--CTLVIPQSRRSDTGLYTITAVNNLGTASKEMR 9905
Query: 1099 LDV 1101
L+V
Sbjct: 9906 LNV 9908
Score = 36.2 bits (82), Expect = 0.18
Identities = 20/94 (21%), Positives = 36/94 (38%), Gaps = 1/94 (1%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P+ ++ + V G+ V + G P P +W +G E+ + +
Sbjct: 11203 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS-S 11261
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
L I DTG Y +N +GS T + + +
Sbjct: 11262 VLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 36.2 bits (82), Expect = 0.18
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G P ++ + G P P++ WK E E TDRVS+ L ++ + + D+G Y
Sbjct: 22357 GSPFTIDVPISGRPAPKVTWKLE-EMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYF 22414
Query: 1084 VSAKNEAGI 1092
++ +N AG+
Sbjct: 22415 LTLENTAGV 22423
Score = 35.8 bits (81), Expect = 0.23
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A F++ L Q V E C+++ V+W+ G+E+ + + G +H
Sbjct: 6516 APTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKKYKFE-KDGSIHR 6573
Query: 329 LIIAEAFEDDTGRYTC 344
LII + DD Y C
Sbjct: 6574 LIIKDCRLDDECEYAC 6589
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 11/127 (8%)
Query: 732 NQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEG 791
NQEY+ C Q + I E + + ++ ++ ++ M ++ G
Sbjct: 12265 NQEYEFRVCAQNQVG-IGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRA-------G 12316
Query: 792 MPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTI 851
P+ V G P PK+ W K G + + +D L ST DD G Y++
Sbjct: 12317 CPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL---VDTMAFLVIPNSTRDDSGKYSL 12373
Query: 852 MAANPQG 858
NP G
Sbjct: 12374 TLVNPAG 12380
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 12/109 (11%)
Query: 992 QNSFSLELVVAAKEAHKPPVFIEKLQN---------TGVADGYPVRLECRVLGVPPPQIF 1042
QN + KEA KP +E + V G P+RL V G P P++
Sbjct: 12275 QNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVT 12334
Query: 1043 WKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
W+K +V + D + L+I +T++D+G Y+++ N AG
Sbjct: 12335 WRKVGIDNVVRKGQVDL-VDTMAF--LVIPNSTRDDSGKYSLTLVNPAG 12380
Score = 35.8 bits (81), Expect = 0.23
Identities = 19/82 (23%), Positives = 35/82 (42%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ ++ + G P PD+ W DGK + +A + +L+++ D
Sbjct: 18412 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18471
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y +N G S + + V
Sbjct: 18472 GQYILKLSNVGGTKSIPITVKV 18493
Score = 35.8 bits (81), Expect = 0.23
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V+ G ++D +SG P P ++ DG P++ + + + E VT+ DAG
Sbjct: 20183 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTA-DAGR 20241
Query: 982 YTCIATNRAGQNSFSLELVV 1001
Y A N +G + +VV
Sbjct: 20242 YEITAANSSGTTKAFINIVV 20261
Score = 35.4 bits (80), Expect = 0.30
Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 986 ATNRAGQNSF---SLELVVAAKEAHKPPVFIEKLQNTGV---ADGYPVRLECRVLGVPPP 1039
A N AG S S E ++ E P + ++ G+ A V +LG P P
Sbjct: 14045 AKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLP 14104
Query: 1040 QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
+ W K + + S ++ L I+ AT++DAG YT++A N G
Sbjct: 14105 KSSWSKAGKDIRPSD--ITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14154
Score = 35.4 bits (80), Expect = 0.30
Identities = 24/60 (40%), Positives = 27/60 (45%), Gaps = 4/60 (6%)
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA-STLDDDGNYTIMAANPQG 858
+ G P PK W K GK I P Q T S+ T +T D G YTI A NP G
Sbjct: 14098 ILGKPLPKSSWSKAGKDIRPSD---ITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14154
Score = 35.4 bits (80), Expect = 0.30
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V G ++ + G P P ++W +EL NT ++I + D T L + +A D+G
Sbjct: 16250 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEI--KSTDFATSLSVKDAVRVDSG 16307
Query: 341 RYTCLATNPSGSDTTSAEV 359
Y A N +G + + V
Sbjct: 16308 NYILKAKNVAGERSVTVNV 16326
Score = 35.4 bits (80), Expect = 0.30
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V G LE V G P P + W KE+ + +I + D LI+ +A D G
Sbjct: 17332 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI--KNTDFKALLIVKDAIRIDGG 17389
Query: 341 RYTCLATNPSGSDTTSAEV 359
+Y A+N +GS + V
Sbjct: 17390 QYILRASNVAGSKSFPVNV 17408
Score = 35.4 bits (80), Expect = 0.30
Identities = 20/85 (23%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+T + G +D +SG P P ++W+L+ ++ + ++ +L ++ D+
Sbjct: 22352 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRT-TLTVKDSMRGDS 22410
Query: 980 GIYTCIATNRAGQNSFSLELVVAAK 1004
G Y N AG +FS+ +VV +
Sbjct: 22411 GRYFLTLENTAGVKTFSVTVVVIGR 22435
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V EG ++ + P P V W +GKE+ + + + + H L + ++ D G
Sbjct: 8093 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGI 8151
Query: 342 YTCLATNPSGSDTTSAEVFIEG 363
YT N GS T S V + G
Sbjct: 8152 YTITLENKLGSATASINVKVIG 8173
Score = 35.0 bits (79), Expect = 0.39
Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS-LIIEPVTSRDAG 980
++ G R+ + G+P P ++W+ + + D+ K + V S L I D G
Sbjct: 10925 IKVGDTLRLSAIIKGVPFPKVTWKKEDR----DAPTKARIDVTPVGSKLEIRNAAHEDGG 10980
Query: 981 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIE 1014
IY+ N AG + S++++V K PP +E
Sbjct: 10981 IYSLTVENPAGSKTVSVKVLVLDKPG--PPRDLE 11012
Score = 35.0 bits (79), Expect = 0.39
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 17/80 (21%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH--------SLII 971
+TV+ G+ R+ +V G P PD++W +G K+LVRE V L I
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEG---------KVLVREKRVDLIQDLPRVELQI 11663
Query: 972 EPVTSRDAGIYTCIATNRAG 991
+ D G Y A N +G
Sbjct: 11664 KEAVRADHGKYIISAKNSSG 11683
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F + V G + ++ G PTP V W + L T +++ E + ++L+
Sbjct: 15843 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQT--TRVNAESTENNSLL 15900
Query: 331 -IAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
I +A +D G Y TN +G + V +
Sbjct: 15901 TIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15932
Score = 35.0 bits (79), Expect = 0.39
Identities = 21/71 (29%), Positives = 29/71 (40%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G LE + G P P V W +GKEL T TL++ + D G+
Sbjct: 18414 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473
Query: 342 YTCLATNPSGS 352
Y +N G+
Sbjct: 18474 YILKLSNVGGT 18484
Score = 35.0 bits (79), Expect = 0.39
Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 4/118 (3%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGVPPPQIFW 1043
A + + S S ++ + P V ++ K ++ V G +++ + G P P I W
Sbjct: 19459 AADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISW 19518
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
K+ + + DNH L ++ + D G Y ++ KN AG S V
Sbjct: 19519 AKDGIEIEERARTEIISTDNH--TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19574
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V +G + L + G P P +W EG+++ I + HT L+I EA D+G
Sbjct: 23843 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIAT----SETHTELVIKEADRGDSG 23898
Query: 341 RYTCLATNPSGSDTTSAEVFIEGASST 367
Y + N G +V + G+ ++
Sbjct: 23899 TYDLVLENKCGKKAVYIKVRVIGSPNS 23925
Score = 34.7 bits (78), Expect = 0.51
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 10/94 (10%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTL-DDDGNY 849
G V F + G P P W DG +I +HYT+ + D S+ T + L D G Y
Sbjct: 11220 GTTVRFPAIIRGVPVPTAKWTTDGSEIK-TDEHYTV--ETDNFSSVLTIKNCLRRDTGEY 11276
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG 883
I +N G + L V V P P+G
Sbjct: 11277 QITVSNAAGSKTVAVHLTVLDV------PGPPTG 11304
Score = 34.7 bits (78), Expect = 0.51
Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G + + RV G P P + W EGK L + + + L I EA D G+
Sbjct: 11615 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL-IQDLPRVELQIKEAVRADHGK 11673
Query: 342 YTCLATNPSGSDTTSAEV 359
Y A N SG SA V
Sbjct: 11674 YIISAKNSSGHAQGSAIV 11691
Score = 34.7 bits (78), Expect = 0.51
Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G + RV G P+P I W K+GK + + + +DL L + D G Y
Sbjct: 11618 GQTIRILARVKGRPEPDITWTKEGK-VLVREKRVDLIQDLP-RVELQIKEAVRADHGKYI 11675
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
I A N G G +V +++ G
Sbjct: 11676 ISAKNSSGH--AQGSAIVNVLDRPG 11698
Score = 34.7 bits (78), Expect = 0.51
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Query: 294 VTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSD 353
+ G P P+ W GK++ + QI L I A D G YT ATNP G+
Sbjct: 14098 ILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKDAGEYTITATNPFGTK 14156
Query: 354 TTSAEVFI 361
+V +
Sbjct: 14157 VEHVKVTV 14164
Score = 34.7 bits (78), Expect = 0.51
Identities = 27/101 (26%), Positives = 52/101 (51%), Gaps = 7/101 (6%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSW-QLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
+ ++ G R+ + G PTP++ W ++DG+ +R D+A ++ + SL+++ V D
Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGE-IR-DAA--IIDVTSSFTSLVLDNVNRYD 16702
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT 1019
+G YT N +G S + V + PPV ++ + T
Sbjct: 16703 SGKYTLTLENSSGTK--SAFVTVRVLDTPSPPVNLKVTEIT 16741
Score = 34.7 bits (78), Expect = 0.51
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 917 PG-DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
PG +TV+ G ++ G P P +SW DG P++ + EN + +L I+
Sbjct: 21264 PGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAK 21322
Query: 976 SRDAGIYTCIATN 988
G YT I N
Sbjct: 21323 KEHGGKYTVILDN 21335
Score = 34.3 bits (77), Expect = 0.67
Identities = 26/129 (20%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Query: 966 VHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF---IEKLQNTGVA 1022
+ ++ + +++ + A N AG ++ V E P F E + V
Sbjct: 14425 ITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVR 14484
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
G +R+ + G P P++ W K+N +L + + ++ + L+I + D G +
Sbjct: 14485 AGLSIRIFVPIKGRPAPEVTWTKDNINLKNRAN----IENTESFTLLIIPECNRYDTGKF 14540
Query: 1083 TVSAKNEAG 1091
++ +N AG
Sbjct: 14541 VMTIENPAG 14549
Score = 33.9 bits (76), Expect = 0.88
Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 3/92 (3%)
Query: 272 RFIQKLRSQ-EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
RF++ L + V +G +YL C + N V W +GK + P + G + L
Sbjct: 4908 RFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALT 4965
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
I +A + D G YT N + + +S +E
Sbjct: 4966 INDADDTDAGTYTVTVENANNLECSSCVKVVE 4997
Score = 33.9 bits (76), Expect = 0.88
Identities = 28/165 (16%), Positives = 63/165 (38%), Gaps = 15/165 (9%)
Query: 942 LSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN--SFSLEL 999
+++ L+ + + + HK+ ++ + D Y A N GQ SF +
Sbjct: 10444 INYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP 10503
Query: 1000 VVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESL--------- 1050
+ E P + ++ + G L R G P P++ W K+ +
Sbjct: 10504 ITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK 10563
Query: 1051 ----THSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
T + +++ + + G C++++ +T G+ V+ + G
Sbjct: 10564 TTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG 10608
Score = 33.9 bits (76), Expect = 0.88
Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS-LIIE 972
L+ G LTV+ G R++ V G P P+++W D + ++ + S +
Sbjct: 11900 LKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT 11959
Query: 973 PVTSRDAGIYTCIATNRAG 991
D G Y ATN AG
Sbjct: 11960 KAKRSDGGKYVVTATNTAG 11978
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 3/74 (4%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFED 337
R+ V G + + + G P P V W + L N +I+ + E L LII E
Sbjct: 14479 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE-NTESFTL--LIIPECNRY 14535
Query: 338 DTGRYTCLATNPSG 351
DTG++ NP+G
Sbjct: 14536 DTGKFVMTIENPAG 14549
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 1027 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 1086
+RL + G P P++ W+K L TDR + + + L+I T+ D+G Y ++
Sbjct: 18820 LRLFVTIKGRPEPEVKWEKAEGIL---TDRAQI-EVTSSFTMLVIDNVTRFDSGRYNLTL 18875
Query: 1087 KNEAGIVSCTARLDVYI 1103
+N +G S TA ++V +
Sbjct: 18876 ENNSG--SKTAFVNVRV 18890
Score = 33.9 bits (76), Expect = 0.88
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V GS + ++ ++G P P+V +G L T +L T+ + E+ D GR
Sbjct: 20183 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL-TINLKESVTADAGR 20241
Query: 342 YTCLATNPSGSDTTSAEVFI 361
Y A N SG TT A + I
Sbjct: 20242 YEITAANSSG--TTKAFINI 20259
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 777 PFFEMKLKHYKIFE---GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
P ++ L++ ++ + G V ++G P P I W+KD K++ + ++ D
Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA-LVCVENTTDLA 20623
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
L A L + G Y + N G S T R+ +
Sbjct: 20624 SILIKDADRL-NSGCYELKLRNAMGSASATIRVQI 20657
Score = 33.9 bits (76), Expect = 0.88
Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 6/110 (5%)
Query: 986 ATNRAGQNS-FSLELVVAAKEA-HKPPVFIEKLQNTGVAD--GYPVRLECRVLGVPPPQI 1041
A N AGQ + V AK+ P + ++ T V G V++ G PPP +
Sbjct: 20939 AVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTV 20998
Query: 1042 FWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
W+K+ ++L S R S+ + + L I T+ D G Y ++ +N G
Sbjct: 20999 TWRKDEKNL-GSDARYSIENTDSSSL-LTIPQVTRNDTGKYILTIENGVG 21046
Score = 33.9 bits (76), Expect = 0.88
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
+ G+ + ++ V+G P +V WF+ G EI+ + I + +L + +
Sbjct: 21665 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST--------SLFVRDA 21716
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVV 538
+ G++T A+N GSA + ++ V
Sbjct: 21717 TRDHRGVYTVEAKNASGSAKAEIKVKV 21743
Score = 33.5 bits (75), Expect = 1.1
Identities = 31/124 (25%), Positives = 49/124 (39%), Gaps = 6/124 (4%)
Query: 982 YTCIATNRAGQNSFS--LELVVAAKEAHKPPVFIEK--LQNTGVADGYPVRLECRVLGVP 1037
Y A NR G + S E + A P +F++ L V G + L V G P
Sbjct: 7354 YRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 7413
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 1097
P+I W K + L D+ ++ + I + + D G Y + A N G +
Sbjct: 7414 EPKITWTKADMIL--KQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVV 7471
Query: 1098 RLDV 1101
++V
Sbjct: 7472 EVNV 7475
Score = 33.5 bits (75), Expect = 1.1
Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 6/84 (7%)
Query: 914 LQAPGD-LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS---- 968
L GD + V+ G+ + V+GLP P + W + + + + +E S
Sbjct: 9096 LSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKT 9155
Query: 969 -LIIEPVTSRDAGIYTCIATNRAG 991
L I D G YT A+NR G
Sbjct: 9156 ELSIPKAVREDKGTYTVTASNRLG 9179
Score = 33.5 bits (75), Expect = 1.1
Identities = 17/73 (23%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G + R+ VSG P P ++W ++ + + ++ + + S++I+
Sbjct: 10229 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS---SMVIKNCQRSHQ 10285
Query: 980 GIYTCIATNRAGQ 992
G+Y+ +A N AG+
Sbjct: 10286 GVYSLLAKNEAGE 10298
Score = 33.5 bits (75), Expect = 1.1
Identities = 49/202 (24%), Positives = 82/202 (40%), Gaps = 21/202 (10%)
Query: 901 NEPIQERFFRPHFLQAPG-DLTV--------QEGKLCRMDCKVSGLPTPDLSWQLDGKPV 951
NEP+Q + L+AP DL V + G+ ++ G P P ++W+ D K +
Sbjct: 20952 NEPVQAK----DILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNL 21007
Query: 952 RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV 1011
D+ + + + L I VT D G Y N G+ S + + P
Sbjct: 21008 GSDARYS-IENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSS----TVSVKVLDTPA 21062
Query: 1012 FIEKLQNTGVADGYPVRL-ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
+KLQ V+ G L + ++ P I + E T T V H+ + L+
Sbjct: 21063 ACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI 21122
Query: 1071 IQGATKEDAGWYTVSAKNEAGI 1092
+++ ++ V A+NE GI
Sbjct: 21123 --DLSEKTPFFFRVLAENEIGI 21142
Score = 33.5 bits (75), Expect = 1.1
Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 8/137 (5%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELV--VAAKEAHKPPVFIEKLQNTG----VADG 1024
+ ++ D + +A N AG S E V ++ + PP + G + G
Sbjct: 22698 VTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAG 22757
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
+ L+ V G P P+I W K ++ L ++VS+ Q +I+ + D+G YT+
Sbjct: 22758 SDLVLDAAVGGKPEPKIIWTKGDKEL-DLCEKVSL-QYTGKRATAVIKFCDRSDSGKYTL 22815
Query: 1085 SAKNEAGIVSCTARLDV 1101
+ KN +G + + + V
Sbjct: 22816 TVKNASGTKAVSVMVKV 22832
Score = 33.1 bits (74), Expect = 1.5
Identities = 31/130 (23%), Positives = 53/130 (40%), Gaps = 18/130 (13%)
Query: 986 ATNRAGQN--SFSLELVVAAKEAHKPPVFIEKLQNTGVAD------GYPVRLECRVLGVP 1037
A N AG++ S + + A +P VFI+ G D G +R+ + G P
Sbjct: 9478 AVNEAGESEPSDTTGEIPATDIQEEPEVFID----IGAQDCLVCKAGSQIRIPAVIKGRP 9533
Query: 1038 PPQIFW------KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
P+ W KK + H + + ++I + G Y+++AKN+AG
Sbjct: 9534 TPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAG 9593
Query: 1092 IVSCTARLDV 1101
+ R+ V
Sbjct: 9594 QKTANCRVKV 9603
Score = 33.1 bits (74), Expect = 1.5
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 12/82 (14%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESL----THSTDRVSMHQDNHGYICLLIQGATKEDA 1079
G +R+ V G PPP + W +L T T +S ++I+ +
Sbjct: 10234 GGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSS--------MVIKNCQRSHQ 10285
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G Y++ AKNEAG T +DV
Sbjct: 10286 GVYSLLAKNEAGERKKTIIVDV 10307
Score = 33.1 bits (74), Expect = 1.5
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 284 EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTGRY 342
E S L+ + G P P V W +G++ T D ++ E ++T LI+ + + D G+Y
Sbjct: 13691 ENSNFRLKIPIKGKPAPSVSWK-KGEDPLAT-DTRVSVESSAVNTTLIVYDCQKSDAGKY 13748
Query: 343 TCLATNPSGSDTTSAEVFIEG 363
T N +G+ + + + G
Sbjct: 13749 TITLKNVAGTKEGTISIKVVG 13769
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
+V GQ + +E + G P + W + G ++ + + + ++ TL I E
Sbjct: 16935 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV--------TDSLDLTTLSIKE 16986
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLV 537
T +D G + + N G T++ ++V
Sbjct: 16987 THKDDGGQYGITVANVVGQKTASIEIV 17013
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
V G R+ G P P+I W +E TD+V + + Y L I + DAG
Sbjct: 17731 VRAGGSARIHIPFKGRPTPEITWSREEGEF---TDKVQI-EKGVNYTQLSIDNCDRNDAG 17786
Query: 1081 WYTVSAKNEAGIVSCTARLDV 1101
Y + +N +G S + V
Sbjct: 17787 KYILKLENSSGSKSAFVTVKV 17807
Score = 33.1 bits (74), Expect = 1.5
Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 296 GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTT 355
G P V W +G+ L T + + + +L I EA ++D G Y +N +GS T
Sbjct: 19115 GRPQATVNWRKDGQTLKETTRVNVS-SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 19173
Query: 356 SAEVFI 361
+ +
Sbjct: 19174 PITIIV 19179
Score = 32.7 bits (73), Expect = 2.0
Identities = 66/322 (20%), Positives = 121/322 (37%), Gaps = 62/322 (19%)
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
+A F K ++ +I EG F C ++ P + W +D K + D Y + D
Sbjct: 6245 LAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLE-SGDKYDVIADGKKRV 6302
Query: 835 SLHTTASTLDDDGNYTIM--AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 892
L +TL D G Y +M AA ++ +L +
Sbjct: 6303 -LVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVV---------------------- 6339
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
P++ D V+E + +C+V+ W + + +
Sbjct: 6340 ----------PLK-------------DTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIF 6375
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF 1012
DS+ ++++++ V++L I D Y TN G+N S ++ +E +
Sbjct: 6376 -DSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLR---I 6431
Query: 1013 IEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
+E L++ + V C+V L V + W K E + +RVS D + ++ L
Sbjct: 6432 VEPLKDIETMEKKSVTFWCKVNRLNV---TLKWTKNGEEVPFD-NRVSYRVDKYKHM-LT 6486
Query: 1071 IQGATKEDAGWYTVSAKNEAGI 1092
I+ D G Y V+A + +
Sbjct: 6487 IKDCGFPDEGEYIVTAGQDKSV 6508
Score = 32.7 bits (73), Expect = 2.0
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD-IQIHCE---GGDLHT-LIIAEAF 335
+V G V++ VTG P P++ W + D +QI E + T L I +A
Sbjct: 9104 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9163
Query: 336 EDDTGRYTCLATNPSGS 352
+D G YT A+N GS
Sbjct: 9164 REDKGTYTVTASNRLGS 9180
Score = 32.7 bits (73), Expect = 2.0
Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ ++D + G P P + W + G ++A + + SL ++ D+
Sbjct: 16248 IVVHAGESFKVDADIYGKPIPTIQW-IKGDQELSNTARLEIKSTDFATSLSVKDAVRVDS 16306
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y A N AG+ S ++ + V
Sbjct: 16307 GNYILKAKNVAGERSVTVNVKV 16328
Score = 32.7 bits (73), Expect = 2.0
Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G+ V LE G P P I W K+ L S I L I+ A KE G YT
Sbjct: 21273 GHNVHLELPYKGKPKPSISWLKDGLPLKES--EFVRFSKTENKITLSIKNAKKEHGGKYT 21330
Query: 1084 VSAKN 1088
V N
Sbjct: 21331 VILDN 21335
Score = 32.3 bits (72), Expect = 2.5
Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 271 PRFIQKLRSQEVA---EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
PR + ++ ++V G + + + G P P + W +G E+ +I D H
Sbjct: 19482 PRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI--ISTDNH 19539
Query: 328 TLI-IAEAFEDDTGRYTCLATNPSGS 352
TL+ + + DTG+Y N +G+
Sbjct: 19540 TLLTVKDCIRRDTGQYVLTLKNVAGT 19565
Score = 32.3 bits (72), Expect = 2.5
Identities = 22/105 (20%), Positives = 47/105 (44%), Gaps = 11/105 (10%)
Query: 437 AYFPPVFTKELQNTAVAE---GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKK 493
+Y PV L+ T V + G V L + G P ++W++ E+Q + +
Sbjct: 20561 SYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCV---- 20616
Query: 494 PRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ +++I + ++G + RN GSA++T ++ +
Sbjct: 20617 ----ENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 20657
Score = 32.3 bits (72), Expect = 2.5
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 918 GDL-TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTS 976
GDL T++ G +D V G P P + W K + D K+ ++ G + +
Sbjct: 22749 GDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCD 22806
Query: 977 R-DAGIYTCIATNRAGQNSFSLELVV 1001
R D+G YT N +G + S+ + V
Sbjct: 22807 RSDSGKYTLTVKNASGTKAVSVMVKV 22832
Score = 32.0 bits (71), Expect = 3.3
Identities = 49/236 (20%), Positives = 90/236 (38%), Gaps = 26/236 (11%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+ I+ LR E V E ++ + V W + KE+ + +I G ++ L +
Sbjct: 2488 KIIRGLRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHG-KIYKLTV 2545
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGAS-------STDSDSESLAFKSRAGAMP 384
+DD G+YT A G + TS ++ + G + T ++S+ F+ A P
Sbjct: 2546 LNMMKDDEGKYTFYA----GENMTSGKLTVAGGAISKPLTDQTVAESQEAVFECEV-ANP 2600
Query: 385 QAQ----KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFP 440
++ + + LT S G +I + ++ Y + + T+
Sbjct: 2601 DSKGEWLRDGKHLPLTNNIRSESDGHKRRLI----IAATKLDDIGEYTYKVATSKTSAKL 2656
Query: 441 PV----FTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
V K L+N V E Q V + VQW + G ++ + + I K
Sbjct: 2657 KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVK 2712
Score = 32.0 bits (71), Expect = 3.3
Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G + L + G PTP V+W GK D I +L++ D+G+
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKW---GKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGK 16705
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SG+ + V
Sbjct: 16706 YTLTLENSSGTKSAFVTV 16723
Score = 32.0 bits (71), Expect = 3.3
Identities = 30/118 (25%), Positives = 44/118 (37%), Gaps = 6/118 (5%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
+P L P + + V G + G PTP + W E E T +QI
Sbjct: 17709 KPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQI 17766
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFK 377
+G + L I +D G+Y N SGS + V + T ++LA K
Sbjct: 17767 E-KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV---LDTPGPPQNLAVK 17820
Score = 32.0 bits (71), Expect = 3.3
Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P ++ K ++ V G LE + G
Sbjct: 18370 FRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGK 18429
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 1094
P P + W K+ + L + R+ + + L+++ + D G Y + N G S
Sbjct: 18430 PIPDVVWSKDGKELEETAARMEI-KSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18486
Score = 31.6 bits (70), Expect = 4.3
Identities = 20/88 (22%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
++ G+ + +E V G P + W + G ++ + + E L I E
Sbjct: 18017 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV--------EETATSTVLHIKE 18068
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVV 538
+D G +T +A N G+AT ++V
Sbjct: 18069 GNKDDFGKYTVTATNSAGTATENLSVIV 18096
Score = 31.6 bits (70), Expect = 4.3
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
G V+LE G P P + W +G L + ++ + TL I A ++ G+YT
Sbjct: 21273 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAKKEHGGKYTV 21331
Query: 345 LATN 348
+ N
Sbjct: 21332 ILDN 21335
Score = 31.6 bits (70), Expect = 4.3
Identities = 22/80 (27%), Positives = 31/80 (38%), Gaps = 3/80 (3%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V+ G R+ G PTP W KP S + + +L +E DAG
Sbjct: 22064 VRAGASIRLFIAYQGRPTPTAVWS---KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGK 22120
Query: 982 YTCIATNRAGQNSFSLELVV 1001
YT N +G S + + V
Sbjct: 22121 YTLTVENNSGSKSITFTVKV 22140
Score = 31.6 bits (70), Expect = 4.3
Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G+ + L G PTP W L DI TL + +D G+
Sbjct: 22064 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT---DSFSTLTVENCNRNDAGK 22120
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SGS + + V
Sbjct: 22121 YTLTVENNSGSKSITFTV 22138
Score = 31.6 bits (70), Expect = 4.3
Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 9/112 (8%)
Query: 770 PVENGMAPFFEMK---LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTI 826
PVE P E+ K I G + V+G P P I W K G ++ ++ I
Sbjct: 23132 PVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA----I 23187
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
+ L D G YTI A N G+ S T ++V+ + G P
Sbjct: 23188 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSAT--VLVKVYDTPGPCP 23237
Score = 31.6 bits (70), Expect = 4.3
Identities = 21/94 (22%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 446 ELQNTAVAEGQVVVLECRVRGAPP-LQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
++ + EG V C++ QV W+ ++++S + I + + +
Sbjct: 25268 QIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE--------DGVA 25319
Query: 505 TLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L + + D G + C NDYG +S A+L V
Sbjct: 25320 ILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25353
Score = 31.2 bits (69), Expect = 5.7
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
A FI K ++ E+ EG + C ++ P V+W + K L + + + G L
Sbjct: 6246 AAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIAD-GKKRVL 6303
Query: 330 IIAEAFEDDTGRYTCL 345
++ +A D G Y +
Sbjct: 6304 VVKDATLQDMGTYVVM 6319
Score = 31.2 bits (69), Expect = 5.7
Identities = 18/69 (26%), Positives = 29/69 (42%), Gaps = 5/69 (7%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P+T PK + WFK+ + +S K+ T ++ S + D G Y
Sbjct: 6709 GKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQ-----TSFRILEAKKGDKGRYK 6763
Query: 851 IMAANPQGR 859
I+ N G+
Sbjct: 6764 IVLQNKHGK 6772
Score = 31.2 bits (69), Expect = 5.7
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G+ VLE +RG P V W + G E++++ + + +ST + TLV+ +
Sbjct: 18414 VHAGETFVLEADIRGKPIPDVVWSKDGKELEET----AARMEIKSTIQK---TTLVVKDC 18466
Query: 512 FPEDAGIFTCSARNDYGS 529
D G + N G+
Sbjct: 18467 IRTDGGQYILKLSNVGGT 18484
Score = 31.2 bits (69), Expect = 5.7
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G+ + L V+G P P + W +G +L + I E L LI+ + D G+
Sbjct: 23153 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDT-TESYSL--LIVDKVNRYDAGK 23209
Query: 342 YTCLATNPSGSDTTSAEV 359
YT A N SG + + V
Sbjct: 23210 YTIEAENQSGKKSATVLV 23227
Score = 31.2 bits (69), Expect = 5.7
Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 7/114 (6%)
Query: 254 NRKSHPQPHSALHFPAAPRFIQKLRSQEV---AEGSRVYLECRVTGNPTPRVRWFCEGKE 310
N + S L A P+F +E A GS + L G P P + WF K
Sbjct: 24304 NEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKL 24363
Query: 311 LHNTPDIQIHCEGGDLHTLIIAEAFEDDT--GRYTCLATNPSGSDTTSAEVFIE 362
L N+ +I I E + +T ++ + + T G+Y +N G+ +V I+
Sbjct: 24364 LQNSENITI--ENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24415
Score = 30.8 bits (68), Expect = 7.4
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Query: 433 GTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
G + Y V T L++ V EG VLEC+V V+W+ +I+ PD R+ Q
Sbjct: 2392 GRVSVYSVDVITP-LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIK--PDDRV-QA 2447
Query: 493 KPRSTAEPEEICTLVIAETFPEDAG 517
+ T + LVI T D G
Sbjct: 2448 IVKGTKQ-----RLVINRTHASDEG 2467
Score = 30.8 bits (68), Expect = 7.4
Identities = 24/95 (25%), Positives = 34/95 (35%), Gaps = 10/95 (10%)
Query: 445 KELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
K ++ V G V +RG P +W GSEI+ + T E +
Sbjct: 11210 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHY---------TVETDNFS 11260
Query: 505 T-LVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ L I D G + + N GS T L V
Sbjct: 11261 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 30.8 bits (68), Expect = 7.4
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 8/76 (10%)
Query: 455 GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPE 514
G+ LE V G PP ++W + G E++ + I + LV ++
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEI--------KIADFSTNLVNKDSTRR 15222
Query: 515 DAGIFTCSARNDYGSA 530
D+G +T +A N G A
Sbjct: 15223 DSGAYTLTATNPGGFA 15238
Score = 30.8 bits (68), Expect = 7.4
Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 9/98 (9%)
Query: 1003 AKEAHKPPVF---IEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSM 1059
AKE + P+F E + V G + G P P + W K + L R
Sbjct: 19872 AKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-----RTRA 19926
Query: 1060 HQDN-HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
+ D L I+ A + D+G YT++ +N S T
Sbjct: 19927 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT 19964
Score = 30.4 bits (67), Expect = 9.7
Identities = 20/94 (21%), Positives = 40/94 (42%), Gaps = 8/94 (8%)
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
+ + G+ + +E V G P +W + E+ S + + S L+
Sbjct: 12601 EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI--------LI 12652
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA 541
I + +D+G ++ +A N G+ T ++VV A
Sbjct: 12653 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 12686
Score = 30.4 bits (67), Expect = 9.7
Identities = 26/119 (21%), Positives = 50/119 (42%), Gaps = 10/119 (8%)
Query: 749 EYRLERSPVDESG--DEVQYGDVP-VENGMAPFFEMKLKHYK---IFEGMPVTFTCRVAG 802
+Y S ++++G + DV VE MAP FE+ + + + G+ + + G
Sbjct: 14438 KYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKG 14497
Query: 803 NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 861
P P++ W KD + +++ + + L D G + + NP G+ S
Sbjct: 14498 RPAPEVTWTKDNINLKNRAN----IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKS 14552
Score = 30.4 bits (67), Expect = 9.7
Identities = 17/60 (28%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 802 GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 861
G PKP I W KDG + K + + +L + + G YT++ N RI+
Sbjct: 21284 GKPKPSISWLKDGLPL--KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIA 21341
Score = 30.4 bits (67), Expect = 9.7
Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P T ++G P PK+ W + ++ ++D +I D T +L S D G Y
Sbjct: 22357 GSPFTIDVPISGRPAPKVTWKLEEMRLK-ETDRVSITTTKDRT-TLTVKDSMRGDSGRYF 22414
Query: 851 IMAANPQG 858
+ N G
Sbjct: 22415 LTLENTAG 22422
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 270 bits (691), Expect = 4e-72
Identities = 197/724 (27%), Positives = 328/724 (45%), Gaps = 76/724 (10%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP L+N V EG+ V LEC + G P V W+R+ +I+ S DF+I +
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG----- 950
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHF 559
I L+I E F ED+G FTCSA N+ G+ +++ L V + ++ E
Sbjct: 951 ---IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEE 1007
Query: 560 QHFPPPPPILETSSL----ELASKKPSEIQQVNNP------ELGLSRAALQMQFNAAER- 608
+ F ++ T + + +P+ + P E G Q+ N
Sbjct: 1008 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1067
Query: 609 --ETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTAR 666
+ +GV + G ++ + + ++ + ++ + K G ++
Sbjct: 1068 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLE 1127
Query: 667 IASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTY---------EERMARRLLGADS 717
A E + ++ ++ + +E + P Y E+ + R+ + D+
Sbjct: 1128 EADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187
Query: 718 ATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDE----SGDEVQYGDVPVEN 773
V E +QE+ +SS E+RLI EIEYR+ ++ ++E G+E D+
Sbjct: 1188 VVVRTYVE------DQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESE 1241
Query: 774 GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
+ F+ ++K+Y+I EGM VTF C+++G P PKI W+KDGK+I + Y + DG
Sbjct: 1242 AVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGR 1300
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR----------------S 877
SL +D+G YT A+N +G C+G+L V+ G S
Sbjct: 1301 ASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLS 1360
Query: 878 PRSPSGHPHVRRPRSRS-----------------RDSGDENEPIQERFFRPHFLQAPGDL 920
PRS S P P S R + +E ER ++P F+ P
Sbjct: 1361 PRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSF 1420
Query: 921 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 980
EG+ R D KV G P P+ W DG+ + D HK++++E+G SLII P T D+G
Sbjct: 1421 KCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSG 1480
Query: 981 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ 1040
+T +A NRAG++S S+ L V A E P+F+EKL+N + +G + ++ R G P P
Sbjct: 1481 EWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPD 1540
Query: 1041 IFWKKENESLT-HSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
I W K ++ + H ++ + + G L I +D+ WYT +A N+AG + ++
Sbjct: 1541 IVWLKNSDIIVPHKYPKIRI-EGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKV 1599
Query: 1100 DVYI 1103
+V +
Sbjct: 1600 NVEV 1603
Score = 143 bits (361), Expect = 8e-34
Identities = 177/741 (23%), Positives = 290/741 (39%), Gaps = 139/741 (18%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P P+ +Q+L+ V G ++G P P++ W+ E ++L +T G +
Sbjct: 3190 PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEY 3248
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387
TL++ EAF +D YTC A N G
Sbjct: 3249 TLLLIEAFPEDAAVYTCEAKNDYGV----------------------------------- 3273
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKEL 447
TTS SL SV V +V SP + +PP L
Sbjct: 3274 -ATTSASL-------------------SVEVPEVVSPDQEM--------PVYPPAIITPL 3305
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
Q+T +EGQ +CRV G L+V W+ + +I+ S FR+ Q E+ L
Sbjct: 3306 QDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQF--------EDTYQLE 3356
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVVT--SANTENCSYESMGESNNDHFQHFPPP 565
IAE +PED G +T A N G +STA L + S EN S S + F+ P
Sbjct: 3357 IAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEP-- 3414
Query: 566 PPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLING 625
+KPS IQ +++ + ++F+A +G+ I
Sbjct: 3415 -----------LGQKPSFIQPLSSLRVHNGET---VRFHA---RVSGIPKPE-----IQW 3452
Query: 626 KANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLE 685
N LPT V+ + L + + A + + A++ + T A +
Sbjct: 3453 FHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTP 3512
Query: 686 RKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLI 745
+ E +L+ R+ E M + + + EE + E ++S I
Sbjct: 3513 KA---PESILHE---RIEQEIEMEMKEFSSSF-----LSAEEEGLHSAELQLSK-----I 3556
Query: 746 SEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPK 805
+E L SPV + + + + G P F ++ + I G T + V G PK
Sbjct: 3557 NETLELLSESPVYPTKFDSE------KEGTGPIFIKEVSNADISMGDVATLSVTVIGIPK 3610
Query: 806 PKIYWFKDGKQISPKSDHYTIQRDLDGTC-SLHTTASTLDDDGNYTIMAANPQGRISCTG 864
PKI WF +G ++P +D+ + DG SL + L+D+G YT MA+N G+ C+
Sbjct: 3611 PKIQWFFNGVLLTPSADYKFV---FDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSA 3667
Query: 865 RLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQE 924
L + N +G GH + ++ P PHFL+ + +
Sbjct: 3668 YLKI---NSKGE------GHKDTETESAVAKSLEKLGGPCP-----PHFLKELKPIRCAQ 3713
Query: 925 GKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTC 984
G + V G P P ++W + K + + ++ NG + I+ D+G+Y C
Sbjct: 3714 GLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYIC 3773
Query: 985 IATNRAGQNSFSLELVVAAKE 1005
A N G+++ + EL+V ++
Sbjct: 3774 KAENMLGESTCAAELLVLLED 3794
Score = 119 bits (299), Expect = 1e-26
Identities = 196/916 (21%), Positives = 336/916 (36%), Gaps = 181/916 (19%)
Query: 213 ALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFP--AA 270
A+ S +SP E + + VKSP + + AV H P A
Sbjct: 26287 AVTSPPRVKSP-EPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAP 26345
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P+ Q L+++ E +++ + V W+ +GK+L Q H + L
Sbjct: 26346 PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 26405
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
I E D G Y C + G+ T+ + + S S+ ++ +KT
Sbjct: 26406 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKV------SKISETKKSDQKT 26459
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT 450
T ++T + PK +P+S PV LQ+T
Sbjct: 26460 TESTVT-RKTEPKAP------EPISSK-----------------------PVIVTGLQDT 26489
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
V+ V + G P W + G I +++ + K E I +
Sbjct: 26490 TVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE--------IHK 26541
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPPILE 570
T D+G++TC+ +N GS +S+ +L + + I +
Sbjct: 26542 TDTSDSGLYTCTVKNSAGSVSSSCKLTIKA---------------------------IKD 26574
Query: 571 TSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSN 630
T + +++++K SEI P+ +A +Q + S
Sbjct: 26575 TEAQKVSTQKTSEI----TPQ---KKAVVQEEI-------------------------SQ 26602
Query: 631 KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGT------KDAVIQDL 684
K+L + + +S K ++ KL ++AS ++ EE++ + K V +++
Sbjct: 26603 KALRSEEIKMSEAK------SQEKLALKEEAS---KVLISEEVKKSAATSLEKSIVHEEI 26653
Query: 685 ERKLRFKEDLLNNG-------QPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYK- 736
+ + E++ + Q + +R+ + A + V + E T ++EY+
Sbjct: 26654 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRY 26713
Query: 737 -VSSCEQRL-ISEIEYRLER-----SPVDESGDEVQYG-DVPVENGMAPFFEMKLKHYKI 788
VS +Q L I + +R E S E + QY + E AP F + + I
Sbjct: 26714 GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNI 26773
Query: 789 FEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGN 848
EG V FTC ++G P P+I WFK+ IS S + +I R + SL +++ D G
Sbjct: 26774 NEGQNVLFTCEISGEPSPEIEWFKNNLPIS-ISSNVSISRSRN-VYSLEIRNASVSDSGK 26831
Query: 849 YTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR--SRDSGDENEPIQE 906
YTI A N +G+ S T LMV P V P R SGD +
Sbjct: 26832 YTIKAKNFRGQCSATASLMVL---------------PLVEEPSREVVLRTSGDTS----- 26871
Query: 907 RFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGV 966
LQ + + + S + S + K SA M + +
Sbjct: 26872 -------LQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMK-FASMSAQSM----SSM 26919
Query: 967 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYP 1026
+E +S GI + Q S ++ A PP + + +G
Sbjct: 26920 QESFVEMSSSSFMGI------SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKV 26973
Query: 1027 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDN-HGYICLLIQGATKEDAGWYTVS 1085
+ + C G P P++ W + HS ++ H +N L+I K+D G YT+S
Sbjct: 26974 LTVACAFTGEPTPEVTWSCGGRKI-HSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLS 27032
Query: 1086 AKNEAGIVSCTARLDV 1101
NE G S T + +
Sbjct: 27033 LGNEFGSDSATVNIHI 27048
Score = 118 bits (295), Expect = 4e-26
Identities = 195/931 (20%), Positives = 327/931 (35%), Gaps = 162/931 (17%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
QP + H APR ++RS V G V PT V+W+ G EL + I
Sbjct: 25994 QPFTLDH---APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHY 26050
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSR 379
G L TL I + DD+G Y + TN G + A + + G T S+ +
Sbjct: 26051 TNTSGVL-TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVP 26109
Query: 380 AGAMPQAQ----------KKTTSVSLTIGSSSPKTGVT-----------TAVIQPLSVPV 418
P+ KKT+ + + K+ +T +A + S +
Sbjct: 26110 RSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 26169
Query: 419 QQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQG 478
++ R TT A + TK T V EG+ C G P V W R+G
Sbjct: 26170 EEKSLEEKSTTRKIKTTLA--ARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKG 26226
Query: 479 SEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ S ++ K +ST E I+ D G ++ N G + L +
Sbjct: 26227 QVLSTSARHQVTTTKYKSTFE--------ISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26278
Query: 539 TSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQ---QVNNPELGLS 595
A + S PP + S E K P ++ +V +PE
Sbjct: 26279 QKARVTEKAVTS--------------PPRV---KSPEPRVKSPEAVKSPKRVKSPEPSHP 26321
Query: 596 RAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKL 655
+A V P+ K PT V P PP + K
Sbjct: 26322 KA---------------VSPTE------------TKPTPTEKVQHLPVSAPPKITQFLKA 26354
Query: 656 GFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMAR----- 710
K+ ++ + ++ + +D +KL+ + TYE ++
Sbjct: 26355 EASKEIAKLTCVVESSVLRAKEVTWYKD-GKKLKENGHFQFHYSADGTYELKINNLTESD 26413
Query: 711 ------RLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEV 764
+ G + N+Q + + KVS ISE + + ++ + +
Sbjct: 26414 QGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSK-----ISETK-KSDQKTTESTVTRK 26467
Query: 765 QYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHY 824
P P L+ + F + G P+P W KDGK I+ + Y
Sbjct: 26468 TEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT-QGGKY 26526
Query: 825 TIQRDLDG----------------TCSLHTTASTLDDDGNYTIMAAN------------- 855
+ D G TC++ +A ++ TI A
Sbjct: 26527 KLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTS 26586
Query: 856 ---PQGRISCTGRL-----------MVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDEN 901
PQ + + M +A +Q + + + + +S + E
Sbjct: 26587 EITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEK 26646
Query: 902 EPIQERF---------FRPH--FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
+ E R H +++ EG+ + ++G D+ W L+G
Sbjct: 26647 SIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVE 26704
Query: 951 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP 1010
+ ++ V + +L I+ + RD GI TCI+ + G +L ++ KE P
Sbjct: 26705 LTNSEEYRYGVSGSD-QTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS-KELSDAP 26762
Query: 1011 VFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
FI + ++ + +G V C + G P P+I W K N ++ S++ VS+ + + Y L
Sbjct: 26763 AFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN-VSISRSRNVY-SLE 26820
Query: 1071 IQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
I+ A+ D+G YT+ AKN G S TA L V
Sbjct: 26821 IRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851
Score = 117 bits (293), Expect = 6e-26
Identities = 102/387 (26%), Positives = 153/387 (39%), Gaps = 67/387 (17%)
Query: 774 GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
G P F L ++ G V F RV+G PKP+I WF + + I P D + G
Sbjct: 3416 GQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGM 3475
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVR----- 888
+ + + G Y+ AAN G +C L V +P++P H R
Sbjct: 3476 ALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTV--------TPKAPESILHERIEQEI 3527
Query: 889 ----RPRSRSRDSGDEN---------------------EPIQERFFR-------PHFLQA 916
+ S S S +E P+ F P F++
Sbjct: 3528 EMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKE 3587
Query: 917 PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTS 976
+ + G + + V G+P P + W +G + P + +K V + HSLII
Sbjct: 3588 VSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKF-VFDGDDHSLIILFTKL 3646
Query: 977 RDAGIYTCIATNRAGQNSFSLELVVAAK-EAHK-------------------PPVFIEKL 1016
D G YTC+A+N G+ S L + +K E HK PP F+++L
Sbjct: 3647 EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKEL 3706
Query: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 1076
+ A G P E V+G P P + W KEN+ L S +H N G ++ +
Sbjct: 3707 KPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN-GSGTFIVNDPQR 3765
Query: 1077 EDAGWYTVSAKNEAGIVSCTARLDVYI 1103
ED+G Y A+N G +C A L V +
Sbjct: 3766 EDSGLYICKAENMLGESTCAAELLVLL 3792
Score = 109 bits (273), Expect = 1e-23
Identities = 88/322 (27%), Positives = 139/322 (43%), Gaps = 27/322 (8%)
Query: 790 EGMPVTFTCRVAG-NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGN 848
EG V + C++ + ++ W+ +Q+ S+ Y I + DG L+ T DDG
Sbjct: 25209 EGGHVKYVCKIENYDQSTQVTWYFGVRQLE-NSEKYEITYE-DGVAILYVKDITKLDDGT 25266
Query: 849 YTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERF 908
Y N G S L V+ V + + RR + + D ++
Sbjct: 25267 YRCKVVNDYGEDSSYAELFVKGVRE--------VYDYYCRRTMKKIKRRTDTMRLLERP- 25317
Query: 909 FRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN--GV 966
P F + T G+ R ++ P P ++W G+ ++P K E+ G+
Sbjct: 25318 --PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGL 25375
Query: 967 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP-------VFIEKLQNT 1019
+ L I VT+ D YT +A N+ G++S +L V H PP +F L N
Sbjct: 25376 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTL---HPPPTDSTLRPMFKRLLANA 25432
Query: 1020 GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 1079
+G V E RV G+PPP + W+K+ + L+ + +H + Y L I+ ED
Sbjct: 25433 ECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH-EGLDYYALHIRDTLPEDT 25491
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G+Y V+A N AG SC A L V
Sbjct: 25492 GYYRVTATNTAGSTSCQAHLQV 25513
Score = 107 bits (268), Expect = 5e-23
Identities = 162/735 (22%), Positives = 270/735 (36%), Gaps = 140/735 (19%)
Query: 444 TKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
TK ++N V E + EC V P + W + G EI+ S F+I+ +
Sbjct: 2839 TKTMKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQG-------- 2887
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLV--------VTSANTENCSYESMGE 553
++ L+I T ED+ +T ND SAT T + + + + ++E
Sbjct: 2888 KLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVN 2947
Query: 554 SNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGV 613
++ I T ++ +KK + + N G +AA+
Sbjct: 2948 YEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFG----------DAADYT---- 2993
Query: 614 HPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPL--LAKPKLGFPKKASR----TARI 667
+ GKA S +L A + K + L K + F + S +
Sbjct: 2994 --------FVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWM 3045
Query: 668 ASDEEIQGTKDAVIQD---LERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVF--- 721
D+E+Q T IQ + R L + + G+ + ++ L + V
Sbjct: 3046 KDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRS 3105
Query: 722 ---NIQEPEEETANQEYKVSS-----------------CEQRLISEIEYRLERSPVDES- 760
+Q E++ A E++V+ ++R +E R+ R + E+
Sbjct: 3106 IKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETR 3165
Query: 761 -GDEVQYGDVPVENGMA----------PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIY 809
D +Y V N + P +L+ + G P F ++G P+PKI
Sbjct: 3166 QSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKIS 3225
Query: 810 WFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ 869
W+K+ + +S + + T L + +D YT A N G + + L V+
Sbjct: 3226 WYKEEQLLSTGFKCKFLHDGQEYTLLL--IEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283
Query: 870 AVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCR 929
P V P D+ P+ + P + D EG+ R
Sbjct: 3284 V--------------PEVVSP--------DQEMPV----YPPAIITPLQDTVTSEGQPAR 3317
Query: 930 MDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR 989
C+VSG +SW K ++P +M E+ + L I D G YT +A+N
Sbjct: 3318 FQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGTYTFVASNA 3375
Query: 990 AGQNS-----------------------FSLELVVAAKEAHKPPVFIEKLQNTGVADGYP 1026
GQ S SL + + + P FI+ L + V +G
Sbjct: 3376 VGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGET 3435
Query: 1027 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 1086
VR RV G+P P+I W + + + D V +++ G +LI A E AG Y+ A
Sbjct: 3436 VRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKA 3495
Query: 1087 KNEAGIVSCTARLDV 1101
N AG +C A L V
Sbjct: 3496 ANSAGEATCAATLTV 3510
Score = 103 bits (258), Expect = 7e-22
Identities = 101/414 (24%), Positives = 174/414 (42%), Gaps = 61/414 (14%)
Query: 154 PKTPHQRKGGPQSQLCDKAANLIEELTSIFKAAKPRNRSPNGESSSPDSGYLSPKNQPSA 213
PKT H G ++ + A +++ S +A+ +S + P + + +P+
Sbjct: 778 PKTEH----GYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRV--RAEPTP 831
Query: 214 LLSASASQSPMEDQGEMEREVKSP---GARHCYQDNQDLAVPHNRKSHPQPHSALHFPAA 270
L + +P + E EVK + V H R++ + + P
Sbjct: 832 LPQFPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVE 891
Query: 271 -----PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGD 325
P + L++ V EG V LEC ++G P+P V W+ E ++ ++ D QI + G
Sbjct: 892 IPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG- 950
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ 385
+ L+I EAF +D+GR+TC A N +G+ +TS + ++ +
Sbjct: 951 IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ-------------------VSEE 991
Query: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF--PPVF 443
+K+TT+V+ + + + V+ + S T P YF PV
Sbjct: 992 FEKETTAVTEKFTTEEKRFVESRDVVMTDT-------SLTEEQAGPGEPAAPYFITKPVV 1044
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
K + EG VV C+V G P V W + G + +++ K T E
Sbjct: 1045 QK------LVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNK--QTGE---- 1092
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNND 557
C LVI+ TF +DAG +T RN +G +++A L+ E YE + +S +
Sbjct: 1093 CKLVISMTFADDAGEYTIVVRNKHGETSASASLL------EEADYELLMKSQQE 1140
Score = 101 bits (252), Expect = 3e-21
Identities = 65/191 (34%), Positives = 102/191 (53%), Gaps = 7/191 (3%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR-ENGVHSL 969
P F Q + V EG + +SG P P++SW DG+ + + + + +G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
I VT ++G Y+ ATN +GQ + + EL+V A+ A PP F+++LQ+ V G VRL
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA--PPNFVQRLQSMTVRQGSQVRL 123
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTD-RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
+ RV G+P P + + ++ + S D ++S D + LLI A ED+G Y+V+A N
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS---LLIAEAYPEDSGTYSVNATN 180
Query: 1089 EAGIVSCTARL 1099
G + TA L
Sbjct: 181 SVGRATSTAEL 191
Score = 95.9 bits (237), Expect = 2e-19
Identities = 95/393 (24%), Positives = 151/393 (38%), Gaps = 92/393 (23%)
Query: 759 ESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQIS 818
E DE Q +E P F +K +K EG F +V G P P+ +WF DG+QI
Sbjct: 1398 EETDESQ-----LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV 1452
Query: 819 PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
H + ++ DGT SL +T D G +T++A N GR S + L V+AV
Sbjct: 1453 NDYTHKVVIKE-DGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV------- 1504
Query: 879 RSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP 938
E +P F++ ++ ++EG M + +G P
Sbjct: 1505 ---------------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1537
Query: 939 TPDLSWQLDGKPVRPDSAHKMLVR-ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSL 997
PD+ W + + P K+ + G +L I+ S+D+ YT A N+AG+++
Sbjct: 1538 NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597
Query: 998 ELVVAA-----------------------------------------------KEAHKPP 1010
++ V KE + P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657
Query: 1011 VFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
F +KL + + P ECR+ +G P + W + + L + +R+ M + GY
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPL-EAANRLRMINE-FGYCS 1715
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
L A D+G T A N+ G +A L V
Sbjct: 1716 LDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1748
Score = 93.2 bits (230), Expect = 1e-18
Identities = 68/261 (26%), Positives = 116/261 (44%), Gaps = 43/261 (16%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F L+ + EG TF ++G P P++ WF+DG+ IS + DG
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
L A T + G Y++ A N G+ + T L+V+A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------------------------- 99
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
E P P+F+Q +TV++G R+ +V+G+PTP + + DG ++ S
Sbjct: 100 ----ETAP-------PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQ-SS 147
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---AHKPPVF 1012
+ +E ++SL+I D+G Y+ ATN G+ + + EL+V +E A K
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 1013 IEKLQNTGVADGYPVRLECRV 1033
+ Q +++ R+E ++
Sbjct: 208 VSTAQ---ISESRQTRIEKKI 225
Score = 89.0 bits (219), Expect = 2e-17
Identities = 44/95 (46%), Positives = 69/95 (72%), Gaps = 1/95 (1%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A P F+Q+L+S V +GS+V L+ RVTG PTP V+++ +G E+ ++ D QI E GDL++
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQE-GDLYS 160
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
L+IAEA+ +D+G Y+ ATN G T++AE+ ++G
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195
Score = 88.6 bits (218), Expect = 3e-17
Identities = 77/323 (23%), Positives = 128/323 (39%), Gaps = 63/323 (19%)
Query: 246 NQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWF 305
N+ L + +P + P FI+++ + +++ G L V G P P+++WF
Sbjct: 3557 NETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWF 3616
Query: 306 CEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI--EG 363
G L + D + +G D H+LII +D G YTC+A+N G SA + I +G
Sbjct: 3617 FNGVLLTPSADYKFVFDGDD-HSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG 3675
Query: 364 ASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHS 423
D+++ES KS ++ L P
Sbjct: 3676 EGHKDTETESAVAKS--------------------------------LEKLGGP------ 3697
Query: 424 PTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQD 483
C P F KEL+ A+G + E V G P V WF++ ++
Sbjct: 3698 -----CPPH----------FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCT 3742
Query: 484 SPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT 543
S + I+ P T ++ + ED+G++ C A N G +T A+L+V +T
Sbjct: 3743 SVYYTIIH-------NPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDT 3795
Query: 544 ENCSYESMGESNNDHFQHFPPPP 566
+ +S + + FP P
Sbjct: 3796 DMTDTPCKAKSTPEAPEDFPQTP 3818
Score = 88.6 bits (218), Expect = 3e-17
Identities = 63/227 (27%), Positives = 93/227 (40%), Gaps = 33/227 (14%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISP--KSDHYTIQRDLDGTC 834
P F + L + + G V F + +P+P + W+K G++I P YT + D G
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESD-KGLY 25376
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 894
L + T DDD YT++A N G SC +L V HP
Sbjct: 25377 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTL-------------HP--------- 25414
Query: 895 RDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
P + RP F + + QEG+ + +VSG+P P L W+ DG+P+
Sbjct: 25415 --------PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLG 25466
Query: 955 SAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+++ ++L I D G Y ATN AG S L V
Sbjct: 25467 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25513
Score = 87.8 bits (216), Expect = 5e-17
Identities = 91/327 (27%), Positives = 140/327 (42%), Gaps = 58/327 (17%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
F +K K+ E F C V+ P + W KD +++ +D IQ++ L
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQI-TDRIKIQKE-KYVHRLLI 3070
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
++ + D G YT++A G +S T +L V+ + R RS +
Sbjct: 3071 PSTRMSDAGKYTVVAG---GNVS-TAKLFVEGRDVRIRSIKK------------------ 3108
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV--RPDSA 956
E + I+++ +A + V E + D W DG + +
Sbjct: 3109 -EVQVIEKQ-------RAVVEFEVNEDDV-------------DAHWYKDGIEINFQVQER 3147
Query: 957 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
HK +V E +H + I DAG YT +A G+N S+ L V A E PP +++L
Sbjct: 3148 HKYVV-ERRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYVNAPE---PPQVLQEL 3199
Query: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 1076
Q V G P R + G P P+I W KE + L+ +H D Y LLI+ A
Sbjct: 3200 QPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLH-DGQEYTLLLIE-AFP 3257
Query: 1077 EDAGWYTVSAKNEAGIVSCTARLDVYI 1103
EDA YT AKN+ G+ + +A L V +
Sbjct: 3258 EDAAVYTCEAKNDYGVATTSASLSVEV 3284
Score = 87.4 bits (215), Expect = 7e-17
Identities = 70/300 (23%), Positives = 129/300 (43%), Gaps = 39/300 (13%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP FI + RSQ + EG V C ++G P+P + WF + + ++ I ++++L
Sbjct: 26761 APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSI-SRSRNVYSL 26819
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI---------EGASSTDSD-SESLAFKSR 379
I A D+G+YT A N G + +A + + E T D S +F S+
Sbjct: 26820 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQ 26879
Query: 380 AGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVP-------------------VQQ 420
+ M ++++ + S + S+S T + A + S+ + Q
Sbjct: 26880 SVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQ 26939
Query: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
+ S TS + + PP + ++ EG+V+ + C G P +V W G +
Sbjct: 26940 LESSTSKMLK---AGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRK 26996
Query: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
I R +++ TL+I + +D G++T S N++GS ++T + + S
Sbjct: 26997 IHSQEQGRF------HIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27050
Score = 83.6 bits (205), Expect = 1e-15
Identities = 65/204 (31%), Positives = 94/204 (46%), Gaps = 26/204 (12%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA-HKMLVRENGVHSL 969
PHF + +L V+ + CKV+G P P + W GK + D +++ + G H L
Sbjct: 24556 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24615
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNS--FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
II VT DA +Y ATN+ G S SLE+ V AK H P +E + G V
Sbjct: 24616 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK-IHLPKT-LEGMGAVHALRGEVV 24673
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLI----------QGATKE 1077
++ G P P I W+K + + DN+G+ +++ G ++
Sbjct: 24674 SIKIPFSGKPDPVITWQKGQDLI-----------DNNGHYQVIVTRSFTSLVFPNGVERK 24722
Query: 1078 DAGWYTVSAKNEAGIVSCTARLDV 1101
DAG+Y V AKN GI T LDV
Sbjct: 24723 DAGFYVVCAKNRFGIDQKTVELDV 24746
Score = 82.4 bits (202), Expect = 2e-15
Identities = 187/867 (21%), Positives = 319/867 (36%), Gaps = 161/867 (18%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
P F +KL S + + ECR+T G+PT V W +GK L +++ E G +
Sbjct: 1657 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC-S 1715
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQK 388
L A+ D+G TC ATN G+D TSA + ++ D +SL +S+ +P+ +K
Sbjct: 1716 LDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK-------DEKSLVEESQ---LPEGRK 1765
Query: 389 KTTSVS--LTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKE 446
+ + TGVTT + +PD Y PV
Sbjct: 1766 GLQRIEELERMAHEGALTGVTTDQKEKQ---------------KPD--IVLYPEPV---- 1804
Query: 447 LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTL 506
V EG+ CRV G P +V W+ G I+ S FR+ + I L
Sbjct: 1805 ----RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV---------RYDGIHYL 1851
Query: 507 VIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPP 566
I + D G +A N G +L + E + P P
Sbjct: 1852 DIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI-----------QQREDFRSVLRRAPEPR 1900
Query: 567 PILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHP--SRGVNGLIN 624
P K E+Q+V+ P + + ++ AER T+ P S +
Sbjct: 1901 PEFHVHE---PGKLQFEVQKVDRP-VDTTETKEVVKLKRAERITHEKVPEESEELRSKFK 1956
Query: 625 GKANSNKSLPTPAVLLSPTKEP---PPLLAKPK---LGFPKKASRTARIASDEEIQGTKD 678
+ AV L K+ LL K K L + K+ + + A EE + T
Sbjct: 1957 RRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIP 2016
Query: 679 AVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQ-----EPEEETANQ 733
D K+ + P++ ER+ + +G S F ++ +PE E
Sbjct: 2017 TFKPD---KIELSPSM---EAPKIF--ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKN 2068
Query: 734 EYKVSSCE-------QRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHY 786
K+ + + + E+ R + + D + V+ ++ E F ++ K
Sbjct: 2069 GVKIERSDRIYWYWPEDNVCELVIR-DVTAEDSASIMVKAINIAGETSSHAFLLVQAKQL 2127
Query: 787 KIF-----------EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
F + TF C + P K+ W+KDG ++ + D Y + D
Sbjct: 2128 ITFTQELQDVVAKEKDTMATFECETS-EPFVKVKWYKDGMEVH-EGDKYRMHSDRKVHFL 2185
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
T T D + ++ + + T +L+V+
Sbjct: 2186 SILTIDTSDAEDYSCVLVEDE--NVKTTAKLIVEGA------------------------ 2219
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
F++ D+ V E ++C VS + W + ++ +
Sbjct: 2220 --------------VVEFVKELQDIEVPESYSGELECIVSP-ENIEGKWYHNDVELKSNG 2264
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK 1015
+ + R G +L ++ VT D G Y+ + + + K +P ++
Sbjct: 2265 KYTITSR-RGRQNLTVKDVTKEDQGEYSFVIDGK--------KTTCKLKMKPRPIAILQG 2315
Query: 1016 LQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGAT 1075
L + V +G V+LE +V + + W K+ + + S DRV + D ++ LLI+ T
Sbjct: 2316 LSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPS-DRVHIVIDKQSHM-LLIEDMT 2372
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDVY 1102
KEDAG Y+ + A +S + R+ VY
Sbjct: 2373 KEDAGNYSFTI--PALGLSTSGRVSVY 2397
Score = 81.6 bits (200), Expect = 4e-15
Identities = 71/279 (25%), Positives = 119/279 (42%), Gaps = 37/279 (13%)
Query: 264 ALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL--HNTPDIQIHC 321
A+ P F++KL++ + EGSR+ ++ R TGNP P + W + H P I+I
Sbjct: 1503 AVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1562
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
G+ L I D+ YT A N +G DTT +V +E + F
Sbjct: 1563 TKGEA-ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-----------VEF----- 1605
Query: 382 AMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP 441
A P+ ++K + + G+ K + ++PL + Q L + P
Sbjct: 1606 AEPEPERK---LIIPRGTYRAKE-IAAPELEPLHLRYGQEQWEEGDLYDKEKQQ----KP 1657
Query: 442 VFTKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
F K+L + + ECR+ G P + V+W G ++ + R++ +
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINE------- 1710
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
C+L + D+GI TC A N YG+ ++A L+V
Sbjct: 1711 -FGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1748
Score = 79.0 bits (193), Expect = 2e-14
Identities = 63/240 (26%), Positives = 100/240 (41%), Gaps = 10/240 (4%)
Query: 772 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRD 829
E PFF+ KL ++ P F CR+ G+P + W DGK + + I
Sbjct: 1652 EKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEF 1711
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889
G CSL + D G T A N G + L+V+ + P G ++R
Sbjct: 1712 --GYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQR 1769
Query: 890 PRSRSRDSGDEN----EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQ 945
R + + Q+ +P + P + V EG+ R C+V+G P P ++W
Sbjct: 1770 IEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWY 1829
Query: 946 LDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
L+G+ +R + + VR +G+H L I S D G A N G ++L + +E
Sbjct: 1830 LNGQLIR--KSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1887
Score = 79.0 bits (193), Expect = 2e-14
Identities = 68/272 (25%), Positives = 110/272 (40%), Gaps = 50/272 (18%)
Query: 742 QRLISEIEYRLERSPVDESGDEVQYG----------DVPVENGMAPFFEMKLKHYKIFEG 791
+ LI +EY R + G E ++ DVP++ AP F+ +L++ +
Sbjct: 24515 KNLIEGLEYEF-RVKCENLGGESEWSEISEPITPKSDVPIQ---APHFKEELRNLNVRYQ 24570
Query: 792 MPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTI 851
T C+V G+PKP + W++ GK+I Y IQ G L + T DD Y +
Sbjct: 24571 SNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQV 24630
Query: 852 MAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRP 911
A N G +S T L V+ + + P
Sbjct: 24631 RATNQGGSVSGTASLEVE----------------------------------VPAKIHLP 24656
Query: 912 HFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLII 971
L+ G + G++ + SG P P ++WQ G+ + ++ H ++ SL+
Sbjct: 24657 KTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ-KGQDLIDNNGHYQVIVTRSFTSLVF 24715
Query: 972 -EPVTSRDAGIYTCIATNRAGQNSFSLELVVA 1002
V +DAG Y A NR G + ++EL VA
Sbjct: 24716 PNGVERKDAGFYVVCAKNRFGIDQKTVELDVA 24747
Score = 77.8 bits (190), Expect = 5e-14
Identities = 42/99 (42%), Positives = 63/99 (63%), Gaps = 8/99 (8%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP F + LQ+ V +G V L+ RV G P V+++R G+EIQ S DF+I Q+
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQE------- 155
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ +L+IAE +PED+G ++ +A N G ATSTA+L+V
Sbjct: 156 -GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 77.4 bits (189), Expect = 7e-14
Identities = 145/666 (21%), Positives = 234/666 (35%), Gaps = 132/666 (19%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
PV ++++ VA G + C ++ AP ++ QWF+ G EI +S I K
Sbjct: 4462 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSK------- 4514
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQ 560
I +L I T D G +TC A N+YGS + TA L VT E + + E
Sbjct: 4515 -YISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERK----- 4568
Query: 561 HFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVN 620
P P E + K+P E E V P +
Sbjct: 4569 ----PEPKEEVVLKSVLRKRP-------------------------EEEEPKVEPKK--- 4596
Query: 621 GLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAV 680
+ + PAV EPPP ++ P R +I ++ K A+
Sbjct: 4597 ---------LEKVKKPAV-----PEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAI 4642
Query: 681 -IQDLERKLRFKEDLLNNGQPRLTYEER-MARRLLGADSATVFNIQEPEEETANQEYKVS 738
+ E K + + ++ P + E +A + + P+EE A + +
Sbjct: 4643 PLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIK 4702
Query: 739 SCEQRLISEIEYRLER--------SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKI-- 788
++ S IE + P DE+ Q VP++ F ++K +
Sbjct: 4703 GVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLK------FVKEIKDIILTE 4756
Query: 789 --FEGMPVTFTCRVAGNPKPKI-YWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 845
F G F C V +P I W KDG I H I D LH L D
Sbjct: 4757 SEFVGSSAIFECLV--SPSTAITTWMKDGSNIRESPKHRFIADGKDR--KLHIIDVQLSD 4812
Query: 846 DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 905
G YT + + T +L+V E +
Sbjct: 4813 AGEYTCVLRLGNKEKTSTAKLVV---------------------------------EELP 4839
Query: 906 ERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENG 965
RF + ++TV +G+ + C+++ D+ W+ DGK V +
Sbjct: 4840 VRFVK----TLEEEVTVVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGL 4893
Query: 966 VHSLIIEPVTSRDAGIYTCIATNRAG-QNSFSLELVVAAKEAHKPPVFIEKLQNTGVADG 1024
+ +L I DAG YT N + S +++V ++ P+ + ++ G A
Sbjct: 4894 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTA-- 4951
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD-NHGYICLLIQGATKEDAGWYT 1083
C + P ++K +E D+ + +D NH Y L I+ A ED Y
Sbjct: 4952 ---IFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLY--LKIKNAMPEDIAEYA 5006
Query: 1084 VSAKNE 1089
V + +
Sbjct: 5007 VEIEGK 5012
Score = 76.6 bits (187), Expect = 1e-13
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 12/195 (6%)
Query: 915 QAPG------DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS 968
+APG D+T + G+ ++ C++ G P PD+ W GK + +KM + H+
Sbjct: 24159 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS-SDGRTHT 24217
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
L + D G+YTCIATN G+ S +L++ A P +++ V G +R
Sbjct: 24218 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAV--GSTLR 24275
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L +G P P + W + L +++ +++ H ++ K AG Y V N
Sbjct: 24276 LHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSN 24334
Query: 1089 EAGIVSCTARLDVYI 1103
G V A LDV I
Sbjct: 24335 VFGTVD--AILDVEI 24347
Score = 75.1 bits (183), Expect = 3e-13
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 42/238 (17%)
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
P++ P + ++TV EG+ ++C +SG P+P ++W + + S +
Sbjct: 889 PVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIE-SSIDFQITF 947
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-------------- 1008
++G+ L+I + D+G +TC A N AG S S L V E +
Sbjct: 948 QSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEE 1007
Query: 1009 ---------------------------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQI 1041
P FI K + +G V C+V G P P +
Sbjct: 1008 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1067
Query: 1042 FWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
+WKK LT + G L+I +DAG YT+ +N+ G S +A L
Sbjct: 1068 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 75.1 bits (183), Expect = 3e-13
Identities = 72/292 (24%), Positives = 121/292 (41%), Gaps = 49/292 (16%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F + ++ +V E R EC V+ P V+W + +EL T I+I E +H L+I
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKY-VHRLLIP 3071
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTS 392
D G+YT +A G + ++A++F+EG + +S + +K+
Sbjct: 3072 STRMSDAGKYTVVA----GGNVSTAKLFVEG--------RDVRIRSIKKEVQVIEKQRAV 3119
Query: 393 VSLTIGSSSPKTGVTTAVIQPLSVPVQQVH----------------------SPTSYLCR 430
V + I+ ++ VQ+ H T R
Sbjct: 3120 VEFEVNEDDVDAHWYKDGIE-INFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR 3178
Query: 431 PDGTTTAYF----PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
+ T Y PP +ELQ V G+ + G P ++ W+++ +
Sbjct: 3179 NRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFK 3238
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ L + +E TL++ E FPEDA ++TC A+NDYG AT++A L V
Sbjct: 3239 CKFLH-------DGQEY-TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 74.3 bits (181), Expect = 6e-13
Identities = 78/323 (24%), Positives = 123/323 (38%), Gaps = 66/323 (20%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHN--TPDIQIHCEGGD 325
PAAP FI K Q++ EG V C+V GNP P V W G L + + + G+
Sbjct: 1033 PAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGE 1092
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ 385
L+I+ F DD G YT + N G + SA + E +D E L KS+ + Q
Sbjct: 1093 C-KLVISMTFADDAGEYTIVVRNKHGETSASASLLEE------ADYE-LLMKSQQEMLYQ 1144
Query: 386 AQKKTTSVSLTIGSSSP--------------------KTGVTTAVIQPL----------- 414
Q +G ++P K T V++
Sbjct: 1145 TQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSF 1204
Query: 415 ------SVPVQQVHSPTSYLCRPDG--------TTTAYFPPVFTKELQNTAVAEGQVVVL 460
+ + + + L DG + + F ++N + EG V
Sbjct: 1205 EERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTF 1264
Query: 461 ECRVRGAPPLQVQWFRQGSEIQDSPDFRI--LQKKPRSTAEPEEICTLVIAETFPEDAGI 518
C++ G P ++ W++ G I+ +++ LQ + +L I PED GI
Sbjct: 1265 HCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQ---------DGRASLRIPVVLPEDEGI 1315
Query: 519 FTCSARNDYGSATSTAQLVVTSA 541
+T A N G+A + +L V A
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPA 1338
Score = 73.9 bits (180), Expect = 8e-13
Identities = 60/269 (22%), Positives = 118/269 (43%), Gaps = 17/269 (6%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F ++++ + EG V C+++G P P++ W+ +GK + + Q+ +L I
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDS--ESLAFKSRAGAMPQAQKKT 390
+D G YT A+N G+ S ++++E A+ + + +L SR ++
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPD-GTTTAYFPPVFTKELQN 449
+ + ++ SP ++ A + P + SP L D + PVF + +
Sbjct: 1367 SPIRMSPARMSP-ARMSPARMSPARM------SPGRRLEETDESQLERLYKPVFVLKPVS 1419
Query: 450 TAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIA 509
EGQ + +V G P + WF G +I + +++ K+ + +L+I
Sbjct: 1420 FKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-------SLIIV 1472
Query: 510 ETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P D+G +T A+N G ++ + L V
Sbjct: 1473 PATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 72.4 bits (176), Expect = 2e-12
Identities = 53/186 (28%), Positives = 86/186 (46%), Gaps = 9/186 (4%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
D +EG + + ++ +++W + K V D K L +N ++L+I+ V + D
Sbjct: 4376 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTED 4432
Query: 979 -AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVP 1037
G Y C A N +G+ + S +L V + A PV K++ VA G+ + C + P
Sbjct: 4433 HQGEYVCEALNDSGKTATSAKLTVVKRAA---PVIKRKIEPLEVALGHLAKFTCEIQSAP 4489
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 1097
+ W K + + +D+ S+ + L I D G YT A NE G VSCTA
Sbjct: 4490 NVRFQWFKAGREI-YESDKCSIRSSKY-ISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 4547
Query: 1098 RLDVYI 1103
L V +
Sbjct: 4548 TLTVTV 4553
Score = 69.7 bits (169), Expect = 1e-11
Identities = 147/793 (18%), Positives = 273/793 (34%), Gaps = 80/793 (10%)
Query: 215 LSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFI 274
+ AS+S ++ Q RE S + + A+ + A R +
Sbjct: 26133 MEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARIL 26192
Query: 275 QKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEA 334
K RS V EG C G P P V W +G+ L + Q+ T I+
Sbjct: 26193 TKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYK-STFEISSV 26251
Query: 335 FEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVS 394
D G Y+ + N G + I+ A T+ S P+ + V
Sbjct: 26252 QASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTS---------PPRVKSPEPRVK 26302
Query: 395 LTIGSSSPKTGVTTAVIQPLSV-PVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVA 453
SPK + P +V P + +PT + PP T+ L+ A A
Sbjct: 26303 SPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH----LPVSAPPKITQFLK--AEA 26356
Query: 454 EGQVVVLECRVRGA--PPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
++ L C V + +V W++ G +++++ F+ T E L I
Sbjct: 26357 SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQ-FHYSADGTYE------LKINNL 26409
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGES-NNDHFQHFPPPPPILE 570
D G + C + G++ + Q + + + + + E+ +D E
Sbjct: 26410 TESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTE 26469
Query: 571 TSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSN 630
+ E S KP + + + + A E + G GK +
Sbjct: 26470 PKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS 26529
Query: 631 KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRF 690
+ + + T L + K ++ + + I+ KD Q K+
Sbjct: 26530 EDKGGFFLEIHKTDTSDSGLYTCTV---KNSAGSVSSSCKLTIKAIKDTEAQ----KVST 26582
Query: 691 KEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEY 750
++ Q + +E ++++ L ++ + + E+ +E + +
Sbjct: 26583 QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAAT 26642
Query: 751 RLERSPVDESGDEVQYGDVPVENGMAPFFEMKL--KHYKIFEGMPVTFTCRVAGNPKPKI 808
LE+S V E + V E+K I EG + +AG K
Sbjct: 26643 SLEKSIVHEEITKTSQASEEVRT----HAEIKAFSTQMSINEGQRLVLKANIAGATDVK- 26697
Query: 809 YWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
W +G +++ ++ D T ++ + D+G T ++ +G + C L +
Sbjct: 26698 -WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHR--DEGILTCISKTKEGIVKCQYDLTL 26754
Query: 869 QAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLC 928
S + +PRS++ + EG+
Sbjct: 26755 --------SKELSDAPAFISQPRSQN---------------------------INEGQNV 26779
Query: 929 RMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATN 988
C++SG P+P++ W + P+ S++ + R V+SL I + D+G YT A N
Sbjct: 26780 LFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKN 26838
Query: 989 RAGQNSFSLELVV 1001
GQ S + L+V
Sbjct: 26839 FRGQCSATASLMV 26851
Score = 69.3 bits (168), Expect = 2e-11
Identities = 120/637 (18%), Positives = 230/637 (36%), Gaps = 71/637 (11%)
Query: 255 RKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT 314
RK+ P+ + + P + L+ V+ S + TG P P W +GK +
Sbjct: 26466 RKTEPKAPEPIS--SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG 26523
Query: 315 PDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL 374
++ + G L I + D+G YTC N +GS ++S ++ I+ T++ S
Sbjct: 26524 GKYKLSEDKGGFF-LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVST 26582
Query: 375 AFKSRAGAMPQA-------QK--KTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT 425
S +A QK ++ + ++ S K + + L + + T
Sbjct: 26583 QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAAT 26642
Query: 426 SY---LCRPDGTTTAYFPPVFTKELQNTA------VAEGQVVVLECRVRGAPPLQVQWFR 476
S + + T T+ + A + EGQ +VL+ + GA V+W
Sbjct: 26643 SLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT--DVKWVL 26700
Query: 477 QGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL 536
G E+ +S ++R + ++ TL I + D GI TC ++ G L
Sbjct: 26701 NGVELTNSEEYRY------GVSGSDQ--TLTIKQASHRDEGILTCISKTKEGIVKCQYDL 26752
Query: 537 VVTSANTENCSYESMGESNN-DHFQHFPPPPPILETSSLELA-SKKPSEIQQVNNPELGL 594
++ ++ ++ S S N + Q+ I S E+ K I +N +
Sbjct: 26753 TLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR 26812
Query: 595 SRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPK 654
SR ++ A +G + + N G+ ++ SL ++ P++E
Sbjct: 26813 SRNVYSLEIRNASVSDSGKYTIKAKN--FRGQCSATASLMVLPLVEEPSREV-------- 26862
Query: 655 LGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLG 714
R + D +QG+ + + K++ + + +
Sbjct: 26863 ---------VLRTSGDTSLQGSFSSQSVQMSAS---KQEASFSSFSSSSASSMTEMKFAS 26910
Query: 715 ADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENG 774
+ ++ ++QE E ++ + S +L S L+ G
Sbjct: 26911 MSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGI----------------RG 26954
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
+ P E I EG +T C G P P++ W G++I + + D
Sbjct: 26955 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 27014
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAV 871
+L D G YT+ N G S T + ++++
Sbjct: 27015 TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27051
Score = 65.5 bits (158), Expect = 3e-10
Identities = 38/105 (36%), Positives = 55/105 (52%), Gaps = 3/105 (2%)
Query: 258 HPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDI 317
HP P + P F + L + E EG V E RV+G P P ++W +G+ L P+I
Sbjct: 25413 HPPPTDST---LRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNI 25469
Query: 318 QIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+I EG D + L I + +DTG Y ATN +GS + A + +E
Sbjct: 25470 EIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25514
Score = 64.7 bits (156), Expect = 5e-10
Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Query: 1009 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
PP + L+N V +G V LEC + G P P + W +E+ + S D Q G
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQS--GIAR 953
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 1104
L+I+ A ED+G +T SA NEAG VS + L V +S
Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 989
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/127 (31%), Positives = 66/127 (51%), Gaps = 4/127 (3%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT--PDIQIHCEGGDLH 327
AP F Q L+S V EGS E ++G P P V WF +G+ + + P +QI G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA- 63
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL-AFKSRAGAMPQA 386
L I + ++GRY+ ATN SG T++AE+ ++ ++ + + L + R G+ +
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 387 QKKTTSV 393
Q + T +
Sbjct: 124 QVRVTGI 130
Score = 62.4 bits (150), Expect = 2e-09
Identities = 198/944 (20%), Positives = 315/944 (33%), Gaps = 199/944 (21%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F L+ V E + EC +T V W +G ++ + D G H L+I
Sbjct: 5116 FAVPLKDVTVPERRQARFECVLTREAN--VIW-SKGPDIIKSSDKFDIIADGKKHILVIN 5172
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGA---------SSTDSDSESLAF------- 376
++ DD G YT TSA +F+ G T + E+ F
Sbjct: 5173 DSQFDDEGVYTAEVEGKK----TSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHE 5228
Query: 377 KSRAGAMPQAQKKTTSVSLTIGSSSP--KTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT 434
K K TS ++ I S K + + +S Q+ + L
Sbjct: 5229 KMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDIS----QIKAQVKELSSTAQL 5284
Query: 435 TTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKP 494
P FT +L + E + L+C V P V+WF+ G EI SP + I
Sbjct: 5285 KVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSPKYSIKADGL 5342
Query: 495 RSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT----------E 544
R L I + +D G + C D A T + + E
Sbjct: 5343 RR--------ILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGE 5394
Query: 545 NCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFN 604
+E + H Q P+ + E+ I ++N +LG++ ++ F
Sbjct: 5395 TAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTG---EVSFQ 5451
Query: 605 AAERETNGVHPSRGVNGLINGKANSN-KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASR 663
AA N K+ +N K P + ++P + + K + F + SR
Sbjct: 5452 AA-----------------NAKSAANLKVKELPLIFITPLSD-VKVFEKDEAKFECEVSR 5493
Query: 664 ----------TARIASDEEIQGTKD----------AVIQDLERKLRFKEDLLNNGQ---- 699
T I D+ + KD A +D + + ED +G+
Sbjct: 5494 EPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIE 5553
Query: 700 -PRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVD 758
RL + + + VF ++ + N K +QRL + ++
Sbjct: 5554 GIRLKFLTPLKDVTAKEKESAVFTVELSHD---NIRVKWFKNDQRLHTTRSVSMQDEGKT 5610
Query: 759 ESGDEVQYGDVPVEN---------GMA-----------PFFEMKLKHYKIFEGMPVTFTC 798
S + + D+ +++ GM+ P+F KL+ Y E V C
Sbjct: 5611 HS---ITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQC 5667
Query: 799 RVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDD-GNYTIMAANPQ 857
++ P + WFKDGK+I P + DG + L D G YT
Sbjct: 5668 EISKADAP-VKWFKDGKEIKPSKNAVI---KADGKKRMLILKKALKSDIGQYTCDC---- 5719
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP 917
G +G+L ++ + P R + S D+ + LQ P
Sbjct: 5720 GTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIH-ANWKLKGEALLQTP 5778
Query: 918 GDLTVQEGKL-------CRMD---------------------CKVSGLPTP--------- 940
+EGK+ CR+D +V GL P
Sbjct: 5779 DCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAG 5838
Query: 941 --------------DLSWQLDGKPVRPDSAHKMLVRENG-VHSLIIEPVTSRDAGIYTCI 985
+ W L GK + P + K++ R G VH+L + V DAG
Sbjct: 5839 ETATFDCELSYEDIPVEWYLKGKKLEP--SDKVVPRSEGKVHTLTLRDVKLEDAGEVQLT 5896
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPV-FIEKLQNTGVADGYPVRLECRVLGVPPPQIFWK 1044
A F + KE PPV F + L++ V +G LEC V ++ W
Sbjct: 5897 A------KDFKTHANLFVKE---PPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWF 5946
Query: 1045 KENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
K + S + + D L+I T ED YT AK+
Sbjct: 5947 KNGTEILKS-KKYEIVADGR-VRKLVIHDCTPEDIKTYTCDAKD 5988
Score = 61.6 bits (148), Expect = 4e-09
Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 7/143 (4%)
Query: 770 PVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD 829
P ++ + P F+ L + + EG V F RV+G P P + W KDG+ +S + I
Sbjct: 25416 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEG 25475
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHP-HVR 888
LD +LH + +D G Y + A N G SC L V+ + + + +S H HV+
Sbjct: 25476 LD-YYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQ 25534
Query: 889 RP-----RSRSRDSGDENEPIQE 906
+ R SG E+ P+ +
Sbjct: 25535 KQIDKTLRMAEILSGTESVPLTQ 25557
Score = 61.2 bits (147), Expect = 5e-09
Identities = 44/184 (23%), Positives = 76/184 (41%), Gaps = 4/184 (2%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P P F+++L+ A+G E V G P P V WF E K+L + I
Sbjct: 3697 PCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 3756
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASSTDSDSESLAFKSRAGAMPQ 385
T I+ + +D+G Y C A N G T +AE V +E TD+ ++ + PQ
Sbjct: 3757 TFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQ 3816
Query: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTK 445
K +V T V +++ + + ++ + + ++ P+ +
Sbjct: 3817 TPLKGPAVEALDSEQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQL--PLGAQ 3874
Query: 446 ELQN 449
ELQ+
Sbjct: 3875 ELQS 3878
Score = 61.2 bits (147), Expect = 5e-09
Identities = 66/266 (24%), Positives = 105/266 (39%), Gaps = 25/266 (9%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+ ++ L S EV E E ++ + W +G+ L TPD +I E G +H+L++
Sbjct: 5736 KLVRPLHSVEVMETETARFETEISEDDI-HANWKLKGEALLQTPDCEIK-EEGKIHSLVL 5793
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG-----------ASSTDSDSESLAFKSRA 380
D TG A N S + + G A T + L+++
Sbjct: 5794 HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP 5853
Query: 381 GAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFP 440
KK + S K V T ++ + + T+ + P
Sbjct: 5854 VEWYLKGKKLEPSDKVVPRSEGK--VHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEP 5911
Query: 441 PV-FTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PV FTK L++ V EG VLEC V +V+WF+ G+EI S + I+
Sbjct: 5912 PVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIV--------A 5962
Query: 500 PEEICTLVIAETFPEDAGIFTCSARN 525
+ LVI + PED +TC A++
Sbjct: 5963 DGRVRKLVIHDCTPEDIKTYTCDAKD 5988
Score = 60.8 bits (146), Expect = 7e-09
Identities = 36/94 (38%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKE-LHNTPDIQIHCEGGDLHT 328
AP F ++LR+ V S L C+VTG+P P V+W+ +GKE + + +I G H
Sbjct: 24555 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24614
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
LIIA +DD Y ATN GS + +A + +E
Sbjct: 24615 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24648
Score = 58.9 bits (141), Expect = 3e-08
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP ++++ G L C++ G P P ++W+ GKEL + ++ + G HTL
Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSD-GRTHTL 24218
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+ ++D G YTC+ATN G TS+++ ++
Sbjct: 24219 TVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24251
Score = 58.2 bits (139), Expect = 4e-08
Identities = 68/279 (24%), Positives = 108/279 (38%), Gaps = 25/279 (8%)
Query: 262 HSALHFPAAP-RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIH 320
H+ L P F + L Q V EG+ LEC V+ +V+WF G E+ + +I
Sbjct: 5903 HANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIV 5961
Query: 321 CEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSA----EVFIEGASSTDSDSESLAF 376
+ G + L+I + +D YTC A + S + F+ + + +A
Sbjct: 5962 AD-GRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMAR 6020
Query: 377 KSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC-----RP 431
+ A+ K I ++ ++ L + + Y C R
Sbjct: 6021 FECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTART 6080
Query: 432 DGTTTAY-FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
G T VFTK L N V+E + L C V P +V W++ EI ++ + IL
Sbjct: 6081 SGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEIL 6139
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTC---SARND 526
+ + LVI EDAG + C S+R D
Sbjct: 6140 TEGRKR--------ILVIQNAHLEDAGNYNCRLPSSRTD 6170
Score = 58.2 bits (139), Expect = 4e-08
Identities = 68/290 (23%), Positives = 101/290 (34%), Gaps = 73/290 (25%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F L ++ G V +T +P P V W+ G+++ + + +
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKY---------- 25367
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
FE D G Y L N + +TD D+E T
Sbjct: 25368 ---TFESDKGLYQ-LTIN---------------SVTTDDDAEY----------------T 25392
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT 450
G S K +T + P PT RP +F + L N
Sbjct: 25393 VVARNKYGEDSCKAKLTVTLHPP----------PTDSTLRP----------MFKRLLANA 25432
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
EGQ V E RV G PP ++W + G + P+ I+ E + L I +
Sbjct: 25433 ECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH-------EGLDYYALHIRD 25485
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQ 560
T PED G + +A N GS + A L V + ++S E + H Q
Sbjct: 25486 TLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSK-EEHERHVQ 25534
Score = 57.4 bits (137), Expect = 7e-08
Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 8/143 (5%)
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG----VAD 1023
S ++E + + A N G++ SL L V ++ PP +L G V
Sbjct: 8981 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKA 9040
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD----NHGYICLLIQGATKEDA 1079
G PV + V G+P P+I W K + TD + + ++ + L I A +ED
Sbjct: 9041 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 9100
Query: 1080 GWYTVSAKNEAGIVSCTARLDVY 1102
G YTV+A N G V ++VY
Sbjct: 9101 GTYTVTASNRLGSVFRNVHVEVY 9123
Score = 55.1 bits (131), Expect = 4e-07
Identities = 60/277 (21%), Positives = 110/277 (39%), Gaps = 45/277 (16%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F KL+ E V L+C ++ P V+WF +GKE+ + + I +G LI
Sbjct: 5646 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKK-RMLI 5703
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
+ +A + D G+YTC G+D TS ++ D + + ++ + +T
Sbjct: 5704 LKKALKSDIGQYTC----DCGTDKTSGKL--------DIEDREIKLVRPLHSVEVMETET 5751
Query: 391 TSVSLTIGSSSPKTG---VTTAVIQPLSVPVQQ---VHSPTSYLCRPDGTTTAYFPPVFT 444
I A++Q +++ +HS + CR D T F
Sbjct: 5752 ARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANV 5811
Query: 445 KE----------------LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
K L++ V G+ +C + + V+W+ +G +++ S
Sbjct: 5812 KSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPSD--- 5867
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARN 525
+ PRS ++ TL + + EDAG +A++
Sbjct: 5868 --KVVPRSEG---KVHTLTLRDVKLEDAGEVQLTAKD 5899
Score = 54.3 bits (129), Expect = 6e-07
Identities = 47/194 (24%), Positives = 82/194 (42%), Gaps = 13/194 (6%)
Query: 757 VDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 816
+++SG + V AP + K++ ++ G FTC + P + WFK G++
Sbjct: 4442 LNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE 4501
Query: 817 ISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV-------- 868
I +SD +I R SL + + D G YT A+N G +SCT L V
Sbjct: 4502 IY-ESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKK 4559
Query: 869 --QAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGK 926
+ + +R P+ V R R + E + + E+ +P + P V+E +
Sbjct: 4560 VRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKL-EKVKKPAVPEPPPPKPVEEVE 4618
Query: 927 LCRMDCKVSGLPTP 940
+ + + +P P
Sbjct: 4619 VPTVTKRERKIPEP 4632
Score = 54.3 bits (129), Expect = 6e-07
Identities = 59/258 (22%), Positives = 105/258 (40%), Gaps = 44/258 (17%)
Query: 773 NGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG 832
+G AP ++K G +C++ G P P I W++ GK++ +S Y + D
Sbjct: 24157 SGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSD-GR 24214
Query: 833 TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 892
T +L +D+G YT +A N G + + +L++QA +P HP
Sbjct: 24215 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA---------TPQFHP------- 24258
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
P++E+++ G R+ G P P ++W G+ +
Sbjct: 24259 --------GYPLKEKYYG------------AVGSTLRLHVMYIGRPVPAMTW-FHGQKLL 24297
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSR-DAGIYTCIATNRAGQNSFSLELVVAAKEAHKP-- 1009
+S + + L+++ V + AG Y +N G L++ + K KP
Sbjct: 24298 QNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDK-PDKPTG 24356
Query: 1010 PVFIEK-LQNTGVADGYP 1026
P+ IE L+N+ V P
Sbjct: 24357 PIVIEALLKNSAVISWKP 24374
Score = 53.5 bits (127), Expect = 1e-06
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 1/97 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
LTV+ G +D V G P P +SW+ DG ++P KM ++ N + +L + V +D+
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12991
Query: 980 GIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
G YT A N +G S +++L V K V I K+
Sbjct: 12992 GDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKM 13028
Score = 52.8 bits (125), Expect = 2e-06
Identities = 77/305 (25%), Positives = 118/305 (38%), Gaps = 60/305 (19%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
F L+ + EG C V+ K+ WFK+G +I KS Y I D L
Sbjct: 5915 FTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEIL-KSKKYEIVAD-GRVRKLVI 5971
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
T +D YT A + + SC ++ PHV
Sbjct: 5972 HDCTPEDIKTYTCDAKD--FKTSCNLNVVP----------------PHVE---------- 6003
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHK 958
FL+ DL V+E ++ R +C++S + W DG ++ +
Sbjct: 6004 --------------FLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAEIKKGKKYD 6048
Query: 959 MLVRENGVHSLIIEPVTSRDAGIYTC-IATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQ 1017
++ + V L+I D Y+C + T R S L V +EA VF + L
Sbjct: 6049 -IISKGAVRILVINKCLLDDEAEYSCEVRTART-----SGMLTVLEEEA----VFTKNLA 6098
Query: 1018 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKE 1077
N V++ ++L C V P ++ W K +E + T R + + I L+IQ A E
Sbjct: 6099 NIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEII-ETGRYEILTEGRKRI-LVIQNAHLE 6155
Query: 1078 DAGWY 1082
DAG Y
Sbjct: 6156 DAGNY 6160
Score = 52.8 bits (125), Expect = 2e-06
Identities = 31/94 (32%), Positives = 47/94 (50%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
P F E+L+N V L C+V G P P + W ++ + + + + + GY L
Sbjct: 24556 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24615
Query: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
+I T +DA Y V A N+ G VS TA L+V +
Sbjct: 24616 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEV 24649
Score = 52.4 bits (124), Expect = 2e-06
Identities = 34/100 (34%), Positives = 46/100 (46%), Gaps = 10/100 (10%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDS--PDFRILQKKPRSTA 498
P FT+ LQ+ V EG E + G P +V WFR G I S P +I R+
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA-- 63
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L I ++G ++ A N G ATSTA+L+V
Sbjct: 64 ------KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 51.6 bits (122), Expect = 4e-06
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 25/271 (9%)
Query: 277 LRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE 336
+++ EV E EC V+ P + W G E+ + +I +G LH LII
Sbjct: 2842 MKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG-KLHQLIIMNTST 2899
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE---SLAFK---SRAGAMPQAQKKT 390
+D+ YT + N S T + + + D ++E ++ F+ + G + K
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP---VFTKEL 447
+ T +T T + +V T + T T Y F K +
Sbjct: 2960 VEIKST-DKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHI 3018
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
++ V E + + EC V P + VQW + E+Q + +I ++K + L+
Sbjct: 3019 KDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEK--------YVHRLL 3069
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
I T DAG +T A G STA+L V
Sbjct: 3070 IPSTRMSDAGKYTVVA----GGNVSTAKLFV 3096
Score = 50.8 bits (120), Expect = 7e-06
Identities = 51/270 (18%), Positives = 102/270 (37%), Gaps = 28/270 (10%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP+ ++++SQ V +GS + RV G P P W+ G ++ + I + ++ L
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCEL 2090
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG----------ASSTDSDSESLAFKSR 379
+I + +D+ A N +G ++ A + ++ + +++A
Sbjct: 2091 VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFEC 2150
Query: 380 AGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC----RPDGTT 435
+ P + K + + + + LS+ Y C + T
Sbjct: 2151 ETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKT 2210
Query: 436 TAYF-----PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
TA F KELQ+ V E LEC V ++ +W+ E++ + + I
Sbjct: 2211 TAKLIVEGAVVEFVKELQDIEVPESYSGELECIV-SPENIEGKWYHNDVELKSNGKYTIT 2269
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFT 520
++ R L + + ED G ++
Sbjct: 2270 SRRGRQ--------NLTVKDVTKEDQGEYS 2291
Score = 50.8 bits (120), Expect = 7e-06
Identities = 35/127 (27%), Positives = 63/127 (49%), Gaps = 3/127 (2%)
Query: 905 QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 964
+E+ P L P +T++ GK R++ V G P P W+ G+ S+H + + +
Sbjct: 12522 KEQLLPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWK-KGEDEVVTSSHLAVHKAD 12579
Query: 965 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA-AKEAHKPPVFIEKLQNTGVAD 1023
LII+ VT +D+G Y+ A N +G ++ +++VV A +PP I + +
Sbjct: 12580 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL 12639
Query: 1024 GYPVRLE 1030
+ + LE
Sbjct: 12640 SWHIPLE 12646
Score = 50.8 bits (120), Expect = 7e-06
Identities = 57/257 (22%), Positives = 97/257 (37%), Gaps = 55/257 (21%)
Query: 284 EGSRVYLECRVTG-NPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRY 342
EG V C++ + + +V W+ ++L N+ +I E G + L + + + D G Y
Sbjct: 25209 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDG-VAILYVKDITKLDDGTY 25267
Query: 343 TCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSP 402
C N G D++ AE+F++G E + R M + +++T ++ L
Sbjct: 25268 RCKVVNDYGEDSSYAELFVKGV------REVYDYYCRR-TMKKIKRRTDTMRL------- 25313
Query: 403 KTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLEC 462
L RP P FT L N G+ V
Sbjct: 25314 -------------------------LERP---------PEFTLPLYNKTAYVGENVRFGV 25339
Query: 463 RVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCS 522
+ P V W++ G +I+ + K + + + L I +D +T
Sbjct: 25340 TITVHPEPHVTWYKSGQKIKPGDN-----DKKYTFESDKGLYQLTINSVTTDDDAEYTVV 25394
Query: 523 ARNDYGSATSTAQLVVT 539
ARN YG + A+L VT
Sbjct: 25395 ARNKYGEDSCKAKLTVT 25411
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/95 (35%), Positives = 56/95 (58%), Gaps = 5/95 (5%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKK-ENESLTHSTDR 1056
E V AKE PP + Q T + G +R+E V G P P WKK E+E +T S
Sbjct: 12516 EGVYEAKEQLLPPKILMPEQIT-IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSS--H 12572
Query: 1057 VSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
+++H+ + I L+I+ T++D+G+Y+++A+N +G
Sbjct: 12573 LAVHKADSSSI-LIIKDVTRKDSGYYSLTAENSSG 12606
Score = 50.1 bits (118), Expect = 1e-05
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHS-TDRVSMHQDNHGYIC 1068
PVF+ K + +G R + +V+G P P+ FW + + + + T +V + +D G
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED--GTQS 1468
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISRH 1106
L+I AT D+G +TV A+N AG S + L V H
Sbjct: 1469 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH 1506
Score = 49.7 bits (117), Expect = 2e-05
Identities = 41/158 (25%), Positives = 67/158 (42%), Gaps = 5/158 (3%)
Query: 205 LSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSA 264
L P ++ +L S S+SP+ M SP AR + R+ S
Sbjct: 1350 LEPVSRIRSLSPRSVSRSPIR----MSPARMSP-ARMSPARMSPARMSPGRRLEETDESQ 1404
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
L P F+ K S + EG + +V G P P WF +G+++ N ++ +
Sbjct: 1405 LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED 1464
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+LII A D+G +T +A N +G + S + +E
Sbjct: 1465 GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1502
Score = 49.7 bits (117), Expect = 2e-05
Identities = 73/280 (26%), Positives = 110/280 (39%), Gaps = 29/280 (10%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F + L + EV+E + L C V+ P V W+ +E+ T +I EG L+I
Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRK-RILVIQ 6150
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFI-EGASSTDSDSESLAFKS--RAGAMPQAQKK 389
A +D G Y C S T +V + E A+ S ++L +A + K+
Sbjct: 6151 NAHLEDAGNYNCRLP----SSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKE 6206
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT-----SYLCRPDGTTTAYFPPVFT 444
+ V + ++G VI V V T +Y+ A V
Sbjct: 6207 SFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIE 6266
Query: 445 K-----ELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
K L++T V E Q VV C V + +WFR I DS + ILQK
Sbjct: 6267 KLRIVVPLKDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQK------- 6318
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYG-SATSTAQLVV 538
+ + TL I + +D + S N G + S A L+V
Sbjct: 6319 -DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 6357
Score = 49.3 bits (116), Expect = 2e-05
Identities = 41/167 (24%), Positives = 69/167 (41%), Gaps = 22/167 (13%)
Query: 195 GESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDL----- 249
G + S DSG ++ + +++ ++D+ + E + P R Q ++L
Sbjct: 1719 GVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH 1778
Query: 250 -----AVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRW 304
V ++K +P L +P R V EG CRVTG P P+V W
Sbjct: 1779 EGALTGVTTDQKEKQKPDIVL-YPEPVR---------VLEGETARFRCRVTGYPQPKVNW 1828
Query: 305 FCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSG 351
+ G+ + + ++ +G +H L I + DTG A NP G
Sbjct: 1829 YLNGQLIRKSKRFRVRYDG--IHYLDIVDCKSYDTGEVKVTAENPEG 1873
Score = 49.3 bits (116), Expect = 2e-05
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 8/98 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P KE+++ G+ L C++ G P ++W+R G E ++Q + +
Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKE--------LIQSRKYKMSSD 24212
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
TL + ED G++TC A N+ G ++++L++
Sbjct: 24213 GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLL 24250
Score = 49.3 bits (116), Expect = 2e-05
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 8/99 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE-IQDSPDFRILQKKPRSTAE 499
P F +EL+N V L C+V G P V+W+RQG E I D +RI + K
Sbjct: 24556 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFK------ 24609
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L+IA +DA ++ A N GS + TA L V
Sbjct: 24610 -GGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24647
Score = 48.1 bits (113), Expect = 4e-05
Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 5/145 (3%)
Query: 960 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFS-LELVVAAKEAHKPPVFIEKLQN 1018
+V E+ V + ++ ++S + A N G++ L + V AK+ P
Sbjct: 17889 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 17948
Query: 1019 TGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKED 1078
+ G +++E V+G P P I W K+ E L +T RV++ + + L I+ K+D
Sbjct: 17949 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT-RVNVEETATSTV-LHIKEGNKDD 18006
Query: 1079 AGWYTVSAKNEAGIVSCTARLDVYI 1103
G YTV+A N AG + T L V +
Sbjct: 18007 FGKYTVTATNSAG--TATENLSVIV 18029
Score = 47.8 bits (112), Expect = 6e-05
Identities = 64/261 (24%), Positives = 98/261 (37%), Gaps = 49/261 (18%)
Query: 619 VNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKD 678
+ GL+ G+ + + P E P+LA LG P R + TK
Sbjct: 8884 ITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYT------ERTKS 8937
Query: 679 AVIQDLERKLRFKEDLLNNGQPRLTYE-----------ERMARRLLGADSATVFNIQEPE 727
+ D +KE N G P Y ER+ +RL S V N+ E +
Sbjct: 8938 TITLD------WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQ 8991
Query: 728 EETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLK--- 784
E++V + + I E E L + V +Q +VP P +++L
Sbjct: 8992 M----YEFRVKAVNE--IGESEPSLPLNVV------IQDDEVP------PTIKLRLSVRG 9033
Query: 785 -HYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD----LDGTCSLHTT 839
K+ G PV V G P PKI W K+ I +D I ++ + L
Sbjct: 9034 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 9093
Query: 840 ASTLDDDGNYTIMAANPQGRI 860
+ +D G YT+ A+N G +
Sbjct: 9094 KAVREDKGTYTVTASNRLGSV 9114
Score = 47.8 bits (112), Expect = 6e-05
Identities = 40/145 (27%), Positives = 70/145 (48%), Gaps = 21/145 (14%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V+A N++G+S G P + + + +P + F + +QA DL
Sbjct: 17913 VKAYNEKGKSDPRVLGVPVIAKDLTI--------QPSLKLPFNTYSIQAGEDL------- 17957
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI-IEPVTSRDAGIYTCIA 986
+++ V G P P++SW DG+P++ + ++ V E +++ I+ D G YT A
Sbjct: 17958 -KIEIPVIGRPRPNISWVKDGEPLKQTT--RVNVEETATSTVLHIKEGNKDDFGKYTVTA 18014
Query: 987 TNRAGQNSFSLELVVAAKEAHKPPV 1011
TN AG + +L ++V K PPV
Sbjct: 18015 TNSAGTATENLSVIVLEKPG--PPV 18037
Score = 47.4 bits (111), Expect = 8e-05
Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 5/110 (4%)
Query: 256 KSHPQ----PHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL 311
KS P+ P A P + + G + +E V G P P + W +G+ L
Sbjct: 17921 KSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL 17980
Query: 312 HNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
T + + E L I E +DD G+YT ATN +G+ T + V +
Sbjct: 17981 KQTTRVNVE-ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029
Score = 46.6 bits (109), Expect = 1e-04
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDD 338
S V G + +E ++G P P + W +G L T I + + DL TL I E +DD
Sbjct: 16866 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV-TDSLDLTTLSIKETHKDD 16924
Query: 339 TGRYTCLATNPSGSDTTSAEV 359
G+Y N G T S E+
Sbjct: 16925 GGQYGITVANVVGQKTASIEI 16945
Score = 46.2 bits (108), Expect = 2e-04
Identities = 48/182 (26%), Positives = 77/182 (42%), Gaps = 19/182 (10%)
Query: 925 GKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTC 984
G +C VS T +W DG +R H+ + + L I V DAG YTC
Sbjct: 4761 GSSAIFECLVSP-STAITTWMKDGSNIRESPKHRFIA-DGKDRKLHIIDVQLSDAGEYTC 4818
Query: 985 IATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQN-TGVADGYPVRLECRVLGVPPPQIFW 1043
+ + + + +LVV P F++ L+ V G P+ L C + + W
Sbjct: 4819 VLRLGNKEKTSTAKLVVE----ELPVRFVKTLEEEVTVVKGQPLYLSCELN--KERDVVW 4872
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLL----IQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
+K+ + + R+ G I L+ I A DAG YTV+ +N A + C++ +
Sbjct: 4873 RKDGKIVVEKPGRIVP-----GVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSSCV 4926
Query: 1100 DV 1101
V
Sbjct: 4927 KV 4928
Score = 46.2 bits (108), Expect = 2e-04
Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query: 997 LELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDR 1056
L + V AK+ PP F V G ++++ +G P P + W K+N L +T R
Sbjct: 15763 LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTT-R 15821
Query: 1057 VSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
V+ + + L I+ A +ED G Y V N AG
Sbjct: 15822 VNAESTENNSL-LTIKDACREDVGHYVVKLTNSAG 15855
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 12/138 (8%)
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRP-DSAHKMLVRENGVHSLIIE 972
LQ D V EG + +++ KVS L + + W DG+ V+P D H ++ +++ H L+IE
Sbjct: 2313 LQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQS--HMLLIE 2369
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
+T DAG Y+ +L L + + + I L++ V +G LEC+
Sbjct: 2370 DMTKEDAGNYSFTIP--------ALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECK 2421
Query: 1033 VLGVPPPQIFWKKENESL 1050
V + W +E +
Sbjct: 2422 VSVPDVTSVKWYLNDEQI 2439
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
AAP +K+ EVA G C + P R +WF G+E++ + I + +
Sbjct: 4460 AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR-SSKYISS 4518
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
L I D G YTC A+N GS + +A + +
Sbjct: 4519 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4551
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTGRYT 343
G LE V+G P P + W +GKEL T ++I D T L+ ++ D+G YT
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI--ADFSTNLVNKDSTRRDSGAYT 15161
Query: 344 CLATNPSG 351
ATNP G
Sbjct: 15162 LTATNPGG 15169
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G +RL V G PPP I W K+ L ++ Y L++ + DAG YT
Sbjct: 23089 GASLRLMVSVSGRPPPVITWSKQGIDLASR----AIIDTTESYSLLIVDKVNRYDAGKYT 23144
Query: 1084 VSAKNEAGIVSCTARLDVY 1102
+ A+N++G S T + VY
Sbjct: 23145 IEAENQSGKKSATVLVKVY 23163
Score = 45.4 bits (106), Expect = 3e-04
Identities = 84/380 (22%), Positives = 138/380 (36%), Gaps = 77/380 (20%)
Query: 760 SGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISP 819
+G+ + G + V G L + E F C VA NP K W +DGK +
Sbjct: 2560 AGENMTSGKLTVAGGA---ISKPLTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPL 2615
Query: 820 KSDHYTIQRDLDG-TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
++ I+ + DG L A+ LDD G YT A + + +L V+AV +
Sbjct: 2616 TNN---IRSESDGHKRRLIIAATKLDDIGEYTYKVATSK----TSAKLKVEAVKIKKTLK 2668
Query: 879 R------------SPSGHPHVRRPR------------------------SRSRDSGDENE 902
HP+V+ + R ++ +E
Sbjct: 2669 NLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDE 2728
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL----DGKPV------- 951
+ FR L A L V+ K+ + V+ L +++++ D PV
Sbjct: 2729 SVYG--FRLGRLGASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSV 2786
Query: 952 --RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP 1009
+P H+ LV E VH L+++ ++ DAG YT + GQ +L V K
Sbjct: 2787 EIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVETLHITK- 2840
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
++N V + EC V P ++ K E ++ + H L
Sbjct: 2841 -----TMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQ---L 2892
Query: 1070 LIQGATKEDAGWYTVSAKNE 1089
+I + ED+ YT N+
Sbjct: 2893 IIMNTSTEDSAEYTFVCGND 2912
Score = 44.7 bits (104), Expect = 5e-04
Identities = 80/363 (22%), Positives = 132/363 (36%), Gaps = 54/363 (14%)
Query: 263 SALHFPAAPRFIQKLRSQE---VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
S+ H PR I LR + V G +C ++ P V W+ +GK+L + +
Sbjct: 5813 SSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVP 5871
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI-EGASSTDSDSESLAFKS 378
EG +HTL + + +D G A + T A +F+ E E +
Sbjct: 5872 RSEG-KVHTLTLRDVKLEDAGEVQLTAKDFK----THANLFVKEPPVEFTKPLEDQTVEE 5926
Query: 379 RAGAMPQAQKKTTSVSLT-------IGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRP 431
A A+ + + + + I S V ++ L + +Y C
Sbjct: 5927 GATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5986
Query: 432 DGTTTA----YFPP--VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSP 485
T+ PP F + L + V E ++ EC + +V+WF+ G+EI+
Sbjct: 5987 KDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGK 6045
Query: 486 DFRILQK---------KPRSTAEPEEICTLVIAE-----TFPEDAGIFTCSARNDYGSAT 531
+ I+ K K E E C + A T E+ +FT + N S T
Sbjct: 6046 KYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANIEVSET 6105
Query: 532 STAQLV--VTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNN 589
T +LV V+ E Y+ E I+ET E+ ++ I + N
Sbjct: 6106 DTIKLVCEVSKPGAEVIWYKGDEE--------------IIETGRYEILTEGRKRILVIQN 6151
Query: 590 PEL 592
L
Sbjct: 6152 AHL 6154
Score = 44.7 bits (104), Expect = 5e-04
Identities = 53/200 (26%), Positives = 88/200 (44%), Gaps = 32/200 (16%)
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH 886
++D D +HT A+ + + +T+ P ++ V AVN +G S S
Sbjct: 23010 EKDTDQWYRVHTNATIRNTE--FTV----PDLKMGQKYSFRVAAVNVKGMSEYS------ 23057
Query: 887 VRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL----TVQEGKLCRMDCKVSGLPTPDL 942
+S E EP+ ER P L+ DL T++ G R+ VSG P P +
Sbjct: 23058 ---------ESIAEIEPV-ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVI 23106
Query: 943 SWQLDGKPVRPDSAHKMLVRENGVHSL-IIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+W G D A + ++ +SL I++ V DAG YT A N++G+ S ++ + V
Sbjct: 23107 TWSKQGI----DLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23162
Query: 1002 AAKEAHKPPVFIEKLQNTGV 1021
P V ++++ V
Sbjct: 23163 YDTPGPCPSVKVKEVSRDSV 23182
Score = 44.3 bits (103), Expect = 6e-04
Identities = 36/106 (33%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNT--GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTD 1055
E V+A H P V ++ V G +R+ RV G P P I W KE + L
Sbjct: 11523 ESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE-K 11581
Query: 1056 RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
RV + QD + L I+ A + D G Y +SAKN +G +A ++V
Sbjct: 11582 RVDLIQD-LPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNV 11626
Score = 44.3 bits (103), Expect = 6e-04
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G + ++ V G P PRV WF +G E+ +++I G +L + +A D G
Sbjct: 21598 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST-SLFVRDATRDHRGV 21656
Query: 342 YTCLATNPSGSDTTSAEVFIE 362
YT A N SGS +V ++
Sbjct: 21657 YTVEAKNASGSAKAEIKVKVQ 21677
Score = 43.9 bits (102), Expect = 8e-04
Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG--VADGYPVRLECRVLGVPPPQIFW 1043
A N G+ + S VVA + P + ++ L + + RL+ + G P P + W
Sbjct: 13585 AENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13644
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
KK + L T RVS+ + + L++ K DAG YT++ KN AG T + V
Sbjct: 13645 KKGEDPLATDT-RVSV-ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13700
Score = 43.9 bits (102), Expect = 8e-04
Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 8/136 (5%)
Query: 744 LISEIEYRLERSPVDESG-DEVQYGDVPV---ENGMAPFFEMKLKHYKIFEGMPVTFTCR 799
L S EY+ +E G + + VPV + + P ++ Y I G +
Sbjct: 17903 LSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIP 17962
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGR 859
V G P+P I W KDG+ + ++ ++ T LH DD G YT+ A N G
Sbjct: 17963 VIGRPRPNISWVKDGEPLK-QTTRVNVEETATSTV-LHIKEGNKDDFGKYTVTATNSAG- 18019
Query: 860 ISCTGRLMVQAVNQRG 875
+ T L V + + G
Sbjct: 18020 -TATENLSVIVLEKPG 18034
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
L V+ G R + G+P P W DG ++ D H + +N L I+ RD
Sbjct: 11148 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDT 11206
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y +N AG + ++ L V
Sbjct: 11207 GEYQITVSNAAGSKTVAVHLTV 11228
Score = 43.5 bits (101), Expect = 0.001
Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSD-HYTIQRDLDGTCSLHTTASTLDDDGNY 849
G V V G P P + W KDG + P +QR+L C+L + D G+Y
Sbjct: 12938 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL---CTLELFSVNRKDSGDY 12994
Query: 850 TIMAANPQGRISCTGRLMV 868
TI A N G S T +L V
Sbjct: 12995 TITAENSSGSKSATIKLKV 13013
Score = 43.5 bits (101), Expect = 0.001
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
++ G+ R++ VSG P P + W DGK + + ++ + + +L+ + T RD+G
Sbjct: 15101 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15159
Query: 982 YTCIATNRAG 991
YT ATN G
Sbjct: 15160 YTLTATNPGG 15169
Score = 43.1 bits (100), Expect = 0.001
Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 18/145 (12%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V AVN++GRS P V + + P A +VQ G+
Sbjct: 16831 VVAVNEKGRSDPRSLAVPIVAK----------------DLVIEPDVKPAFSSYSVQVGQD 16874
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIAT 987
+++ +SG P P ++W DG P++ + + + +L I+ D G Y
Sbjct: 16875 LKIEVPISGRPKPTITWTKDGLPLK-QTTRINVTDSLDLTTLSIKETHKDDGGQYGITVA 16933
Query: 988 NRAGQNSFSLELVVAAK-EAHKPPV 1011
N GQ + S+E+V K + K PV
Sbjct: 16934 NVVGQKTASIEIVTLDKPDPPKGPV 16958
Score = 42.7 bits (99), Expect = 0.002
Identities = 59/256 (23%), Positives = 100/256 (39%), Gaps = 28/256 (10%)
Query: 277 LRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE 336
L Q VAE EC V NP + W +GK L T +I+ + G LIIA
Sbjct: 2580 LTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPLTNNIRSESD-GHKRRLIIAATKL 2637
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGA-------SSTDSDSESLAFKSRAGAMPQAQKK 389
DD G YT + TSA++ +E + T ++++ F P +
Sbjct: 2638 DDIGEYTYKV----ATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL-THPNVKGV 2692
Query: 390 TTSVSLTIGSSSPKTGVTT-AVIQPLSVPVQQVHSPTSY---LCRPDGTTTAYFPPV-FT 444
+ + S+ K ++ I L + + + Y L R + + V
Sbjct: 2693 QWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKII 2752
Query: 445 KELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
K+ ++ E V E V + V+WF + EI+ S R++ ++ ++
Sbjct: 2753 KKPKDVTALENATVAFEVSV-SHDTVPVKWFHKSVEIKPSDKHRLVSER--------KVH 2803
Query: 505 TLVIAETFPEDAGIFT 520
L++ P DAG +T
Sbjct: 2804 KLMLQNISPSDAGEYT 2819
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG---VADGYPVRLECRVLGVPPPQIF 1042
A N AG+ V E +PP + G + G +R+ V G P P
Sbjct: 8706 AVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8765
Query: 1043 WKKENESLTHSTDRVSMHQDNHGYIC-LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
W KE L DRV + DN G L+I+ A ++D G Y ++A N G AR++V
Sbjct: 8766 WTKEEGEL--DKDRVVI--DNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8821
Query: 1102 Y 1102
+
Sbjct: 8822 F 8822
Score = 42.7 bits (99), Expect = 0.002
Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELV--VAAKEAHKPPVFIEKLQNTGVAD---G 1024
II +T + A N G S E+V + +++ PV L+ T V G
Sbjct: 20456 IISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAG 20515
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
V+L + G P P I W K+++ L T+ + ++ +LI+ A + ++G Y +
Sbjct: 20516 TSVKLRAGISGKPAPTIEWYKDDKEL--QTNALVCVENTTDLASILIKDADRLNSGCYEL 20573
Query: 1085 SAKNEAGIVSCTARLDV 1101
+N G S T R+ +
Sbjct: 20574 KLRNAMGSASATIRVQI 20590
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
I G + V G P P++ WFKDG +I + + D+ G+ SL +T D G
Sbjct: 21598 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI--TDVLGSTSLFVRDATRDHRG 21655
Query: 848 NYTIMAANPQGRISCTGRLMVQ 869
YT+ A N G ++ VQ
Sbjct: 21656 VYTVEAKNASGSAKAEIKVKVQ 21677
Score = 42.4 bits (98), Expect = 0.002
Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 11/105 (10%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G ++ +E V G P P +W E+ + + +H + LII + D+G
Sbjct: 12538 IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVH-KADSSSILIIKDVTRKDSGY 12596
Query: 342 YTCLATNPSGSDTTSAEVFIEGA----------SSTDSDSESLAF 376
Y+ A N SG+DT +V + A S D+D+ SL++
Sbjct: 12597 YSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSW 12641
Score = 42.0 bits (97), Expect = 0.003
Identities = 41/146 (28%), Positives = 60/146 (41%), Gaps = 19/146 (13%)
Query: 402 PKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAY----FPPVFTKELQNTAVAEGQV 457
P GV P+ +++ + PD Y P F KE+++ + E +
Sbjct: 4700 PIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEF 4759
Query: 458 V----VLECRVRGAPPLQVQWFRQGSEIQDSPDFR-ILQKKPRSTAEPEEICTLVIAETF 512
V + EC V + + W + GS I++SP R I K R L I +
Sbjct: 4760 VGSSAIFECLVSPSTAITT-WMKDGSNIRESPKHRFIADGKDRK---------LHIIDVQ 4809
Query: 513 PEDAGIFTCSARNDYGSATSTAQLVV 538
DAG +TC R TSTA+LVV
Sbjct: 4810 LSDAGEYTCVLRLGNKEKTSTAKLVV 4835
Score = 42.0 bits (97), Expect = 0.003
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A P F KL + E + L+C V+ + V+WF +G+E+ +P I + G
Sbjct: 5289 ADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSPKYSIKAD-GLRRI 5345
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
L I +A D G Y C G+D T A V +E
Sbjct: 5346 LKIKKADLKDKGEYVC----DCGTDKTKANVTVE 5375
Score = 42.0 bits (97), Expect = 0.003
Identities = 61/251 (24%), Positives = 94/251 (37%), Gaps = 50/251 (19%)
Query: 783 LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 842
LK ++ E V F C V K WF++ + I S + +Q+DL +L +
Sbjct: 6274 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDL--VYTLRIRDAH 6330
Query: 843 LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENE 902
LDD NY V N RG + +S + N
Sbjct: 6331 LDDQANYN-----------------VSLTNHRGENVKSAA------------------NL 6355
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
++E R ++ D+ E K CKV+ L L W +G+ V D+ V
Sbjct: 6356 IVEEEDLR--IVEPLKDIETMEKKSVTFWCKVNRL-NVTLKWTKNGEEVPFDNRVSYRV- 6411
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVA 1022
+ H L I+ D G Y I T AGQ+ EL++ P F+E L++ V
Sbjct: 6412 DKYKHMLTIKDCGFPDEGEY--IVT--AGQDKSVAELLI----IEAPTEFVEHLEDQTVT 6463
Query: 1023 DGYPVRLECRV 1033
+ C++
Sbjct: 6464 EFDDAVFSCQL 6474
Score = 42.0 bits (97), Expect = 0.003
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFED 337
R Q + G + L + G P P+V W E ++ I + G L I A +
Sbjct: 10854 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLE---IRNAAHE 10910
Query: 338 DTGRYTCLATNPSGSDTTSAEVFI 361
D G Y+ NP+GS T S +V +
Sbjct: 10911 DGGIYSLTVENPAGSKTVSVKVLV 10934
Score = 42.0 bits (97), Expect = 0.003
Identities = 42/170 (24%), Positives = 73/170 (42%), Gaps = 13/170 (7%)
Query: 939 TPDLSWQLDGKPVRPDS---AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSF 995
+P+LS+ ++ + D HK ++E +++ + N G++ +
Sbjct: 11758 SPNLSYHVERRLKGSDDWERVHKGSIKET---HYMVDRCVENQIYEFRVQTKNEGGESDW 11814
Query: 996 SLELVVAAKEAHKPPVFIEKLQNT-GVADGYPVRLECRVLGVPPPQIFWKKENES--LTH 1052
V KE + PV KL V G +RLE V G P P++ W K+ ++ LT
Sbjct: 11815 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11874
Query: 1053 STD-RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
S ++ D+ + + A + D G Y V+A N AG A ++V
Sbjct: 11875 SPRVKIDTRADSSKF---SLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNS-FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
+I +T + ++ +A N G++ SL + + AK+ P + V G ++
Sbjct: 16817 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 16876
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
+E + G P P I W K+ L +T R+++ D+ L I+ K+D G Y ++ N
Sbjct: 16877 IEVPISGRPKPTITWTKDGLPLKQTT-RINV-TDSLDLTTLSIKETHKDDGGQYGITVAN 16934
Query: 1089 EAG 1091
G
Sbjct: 16935 VVG 16937
Score = 41.6 bits (96), Expect = 0.004
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSR- 977
D+ V EG+ + +P P +SW DGK V+ ++ ++ ++ + + + + P + R
Sbjct: 8023 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK--ASDRLTMKNDHISAHLEVPKSVRA 8080
Query: 978 DAGIYTCIATNRAGQNSFSLELVV 1001
DAGIYT N+ G + S+ + V
Sbjct: 8081 DAGIYTITLENKLGSATASINVKV 8104
Score = 41.6 bits (96), Expect = 0.004
Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
P + KE V EG V + +++G P + WF+ + D+ + +L +
Sbjct: 9746 PSIDLKEFME--VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLV 9802
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ CTLVI ++ D G++T +A N+ G+A+ +L V
Sbjct: 9803 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9841
Score = 41.6 bits (96), Expect = 0.004
Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 12/100 (12%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE------- 972
+ V+EG + K+ G+P P L+W P +PD+ +L + V+ L+++
Sbjct: 9754 MEVEEGTNVNIVAKIKGVPFPTLTW-FKAPPKKPDNKEPVLY-DTHVNKLVVDDTCTLVI 9811
Query: 973 PVTSR-DAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV 1011
P + R D G+YT A N G S + L V + PPV
Sbjct: 9812 PQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPG--PPV 9849
Score = 41.6 bits (96), Expect = 0.004
Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 4/82 (4%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL-IQGATKEDA 1079
V G V L+ V G P P + WKK+ +L + + M + +C L + ++D+
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRN--LCTLELFSVNRKDS 12991
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G YT++A+N +G S T +L V
Sbjct: 12992 GDYTITAENSSGSKSATIKLKV 13013
Score = 41.2 bits (95), Expect = 0.005
Identities = 35/149 (23%), Positives = 64/149 (42%), Gaps = 17/149 (11%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V AVN++GRS G P + R E +P E F ++A L
Sbjct: 18996 VAAVNEKGRSDPRQLGVPVIAR--------DIEIKPSVELPFHTFNVKAREQL------- 19040
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIAT 987
++D G P ++W+ DG+ ++ ++ + V SL I+ + D G Y +
Sbjct: 19041 -KIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 19098
Query: 988 NRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
N AG + + ++V + P+ I+++
Sbjct: 19099 NSAGSITVPITIIVLDRPGPPGPIRIDEV 19127
Score = 41.2 bits (95), Expect = 0.005
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
Query: 1000 VVAAKEAHKPPVFI---EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDR 1056
++ ++ + PP+ E + G +R++ V G P P++ W K+ + R
Sbjct: 21574 IIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEK---R 21630
Query: 1057 VSMH-QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
++M D G L ++ AT++ G YTV AKN +G ++ V
Sbjct: 21631 MNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21676
Score = 41.2 bits (95), Expect = 0.005
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
GS ++ ++G P P+V W E L T + I D TL + ++ D+GRY
Sbjct: 22290 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYFL 22348
Query: 345 LATNPSGSDTTSAEVFIEG 363
N +G T S V + G
Sbjct: 22349 TLENTAGVKTFSVTVVVIG 22367
Score = 40.8 bits (94), Expect = 0.007
Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 20/205 (9%)
Query: 678 DAVIQDLERK---LRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQE 734
D + D RK + +K N G P + Y M +G + N + ++ +
Sbjct: 7918 DLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP--VGTEKWMRVNSRPIKD----LK 7971
Query: 735 YKVSSCEQRLISEIEYRLERSPVDESG----DEVQYGDVPVENGMAPFFEMKLKHYKIFE 790
+KV E+ ++ + EY L V+ G E+ V + P +++ + E
Sbjct: 7972 FKV---EEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIE 8028
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G ++ P P + W KDGK++ SD T++ D + L S D G YT
Sbjct: 8029 GEKLSIPVPFRAVPVPTVSWHKDGKEVK-ASDRLTMKND-HISAHLEVPKSVRADAGIYT 8086
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
I N G S T + V+ + G
Sbjct: 8087 ITLENKLG--SATASINVKVIGLPG 8109
Score = 40.8 bits (94), Expect = 0.007
Identities = 32/106 (30%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRV 1057
E VVA KP + +E + V +G + + VP P + W K+ + + S DR+
Sbjct: 8004 ENVVAKDPDCKPTIDLET-HDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKAS-DRL 8061
Query: 1058 SMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
+M D H L + + + DAG YT++ +N+ G S TA ++V +
Sbjct: 8062 TMKND-HISAHLEVPKSVRADAGIYTITLENKLG--SATASINVKV 8104
Score = 40.8 bits (94), Expect = 0.007
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P E + V EG+ + + R P V W + G E++ S R+ K +A
Sbjct: 8015 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD--RLTMKNDHISAH- 8071
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L + ++ DAGI+T + N GSAT++ + V
Sbjct: 8072 -----LEVPKSVRADAGIYTITLENKLGSATASINVKV 8104
Score = 40.8 bits (94), Expect = 0.007
Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 8/100 (8%)
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFK------DGKQISPKSDHYTIQR 828
M P ++K + ++ EG V ++ G P P + WFK D K+ H +
Sbjct: 9744 MPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KL 9801
Query: 829 DLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
+D TC+L S D G YTI A N G S RL V
Sbjct: 9802 VVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9841
Score = 40.4 bits (93), Expect = 0.009
Identities = 52/218 (23%), Positives = 83/218 (38%), Gaps = 51/218 (23%)
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
+GG T + EA + T R+ + T +E ++ ++ E F+ RA
Sbjct: 23289 DGGSRLTGYVLEACKAGTERWMKVVT--------LKPTVLEHTVTSLNEGEQYLFRIRA- 23339
Query: 382 AMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP 441
Q +K G S P+ VT +Q L V PT L
Sbjct: 23340 ---QNEK---------GVSEPRETVTAVTVQDLRV------LPTIDLS------------ 23369
Query: 442 VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
T + V G+ V L + G PP WF GS++++S R T E
Sbjct: 23370 --TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRES---------ERVTVETH 23418
Query: 502 -EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ L I ET D G +T +N G+ + T ++++
Sbjct: 23419 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVII 23456
Score = 40.0 bits (92), Expect = 0.012
Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G T R +G PKPK+ WFKD + D T + T +L + D G Y
Sbjct: 10461 GEAFALTGRYSGKPKPKVSWFKDEADV--LEDDRTHIKTTPATLALEKIKAKRSDSGKYC 10518
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
++ N G S G V V++ G
Sbjct: 10519 VVVENSTG--SRKGFCQVNVVDRPG 10541
Score = 39.7 bits (91), Expect = 0.016
Identities = 74/339 (21%), Positives = 122/339 (35%), Gaps = 77/339 (22%)
Query: 758 DESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQI 817
D+S E+ + P E F L+ + E F+C+++ K + W+++G++I
Sbjct: 6438 DKSVAELLIIEAPTE------FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNGREI 6490
Query: 818 SPKSDHYTIQRDLDGTCSLHTTA---STLDDDGNYTIMAANPQGRISCTGRLMVQAVNQR 874
+ Y ++D S+H LDD+ Y + + R RL V+ +
Sbjct: 6491 K-EGKKYKFEKD----GSIHRLIIKDCRLDDECEYACGVEDRKSR----ARLFVEEI--- 6538
Query: 875 GRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRP--HFLQAPGDLTVQEGKLCRMDC 932
P++ RP L+APG V +L +
Sbjct: 6539 ----------------------------PVE--IIRPPQDILEAPGADVVFLAELNKDKV 6568
Query: 933 KVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQ 992
+V W + V H+M+ E +H L I + RD G Y IA ++ +
Sbjct: 6569 EVQ--------WLRNNMVVVQGDKHQMM-SEGKIHRLQICDIKPRDQGEYRFIAKDKEAR 6619
Query: 993 NSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTH 1052
L K A Q+ V G P+ + P + W KENE L+
Sbjct: 6620 AKLELAAAPKIKTAD---------QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLST 6670
Query: 1053 STDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
T + Q + I A K D G Y + +N+ G
Sbjct: 6671 KTIDTTAEQTS-----FRILEAKKGDKGRYKIVLQNKHG 6704
Score = 39.7 bits (91), Expect = 0.016
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
++ G + + VTG P P W E EL D + G LII +A D G
Sbjct: 8743 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDK--DRVVIDNVGTKSELIIKDALRKDHG 8800
Query: 341 RYTCLATNPSGSDTTSAEV 359
RY ATN GS +A V
Sbjct: 8801 RYVITATNSCGSKFAAARV 8819
Score = 39.7 bits (91), Expect = 0.016
Identities = 41/146 (28%), Positives = 60/146 (41%), Gaps = 24/146 (16%)
Query: 865 RLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQE 924
R V+AVN+ G S P + D +E E + + A L +
Sbjct: 9406 RFRVKAVNEAGES------EPSDTTGEIPATDIQEEPEVFID-------IGAQDCLVCKA 9452
Query: 925 GKLCRMDCKVSGLPTPDLSWQLDGKPVR--PDSAH------KMLVRENGVHSLIIEPVTS 976
G R+ + G PTP SW+ DGK + D H ++ EN S+II P
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENS--SVIIIPECK 9510
Query: 977 RD-AGIYTCIATNRAGQNSFSLELVV 1001
R G Y+ A N+AGQ + + + V
Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKV 9536
Score = 39.7 bits (91), Expect = 0.016
Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 9/138 (6%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF-----IEKLQNTGVADG 1024
++ +T + + +A N AG+++ V KE P +KL D
Sbjct: 14651 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDN 14710
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
+++E VLG P P + WKK + + T RV+ I L I + D+G Y +
Sbjct: 14711 --IKVEIPVLGRPKPTVTWKK-GDQILKQTQRVNFETTATSTI-LNINECVRSDSGPYPL 14766
Query: 1085 SAKNEAGIVSCTARLDVY 1102
+A+N G V + V+
Sbjct: 14767 TARNIVGEVGDVITIQVH 14784
Score = 39.7 bits (91), Expect = 0.016
Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 7/125 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P + ++ K ++T V G +++ + G
Sbjct: 16139 FRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGK 16198
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
P P I W K ++ L++ T R+ + + L ++ A + D+G Y + AKN AG S T
Sbjct: 16199 PIPTIQWIKGDQELSN-TARLEIKSTDFA-TSLSVKDAVRVDSGNYILKAKNVAGERSVT 16256
Query: 1097 ARLDV 1101
+ V
Sbjct: 16257 VNVKV 16261
Score = 39.3 bits (90), Expect = 0.021
Identities = 42/174 (24%), Positives = 69/174 (39%), Gaps = 12/174 (6%)
Query: 688 LRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISE 747
L+++ + G P L+Y + RRL G+D + +E Y V C + I
Sbjct: 11747 LKWRRPDYDGGSPNLSYH--VERRLKGSDDWERVHKGSIKET----HYMVDRCVENQI-- 11798
Query: 748 IEYRLERSPVDESGDEVQYGDVPVENGMA-PFFEMKLKHY-KIFEGMPVTFTCRVAGNPK 805
E+R++ D V+ +V V+ + P ++KL + G + V G P
Sbjct: 11799 YEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPF 11858
Query: 806 PKIYWFKDGKQIS-PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQG 858
P++ W KD +S I D + T + D G Y + A N G
Sbjct: 11859 PEVAWTKDKDATDLTRSPRVKIDTRADSS-KFSLTKAKRSDGGKYVVTATNTAG 11911
Score = 39.3 bits (90), Expect = 0.021
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI-IEPVTSRD 978
+ V+ G++ +++ ++G P P +SW DG + + +++ +N H+L+ ++ RD
Sbjct: 19427 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN--HTLLTVKDCIRRD 19484
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAK 1004
G Y N AG S ++ V K
Sbjct: 19485 TGQYVLTLKNVAGTRSVAVNCKVLDK 19510
Score = 38.9 bits (89), Expect = 0.027
Identities = 63/282 (22%), Positives = 102/282 (36%), Gaps = 24/282 (8%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
I L+ V EG++ LEC+V+ V+W+ +++ +Q + G L+I
Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK-GTKQRLVINR 2460
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASS-TDSDSESLAFK---SRAGAMPQAQ 387
D G Y + + S E I G T ++++++ F+ S +G
Sbjct: 2461 THASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWN 2520
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPV----F 443
K + SS I L+V Y T+ V
Sbjct: 2521 FKDKEIK----PSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAI 2576
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
+K L + VAE Q V EC V P + +W R G + L RS ++ +
Sbjct: 2577 SKPLTDQTVAESQEAVFECEVAN-PDSKGEWLRDGKHLP-------LTNNIRSESDGHK- 2627
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTEN 545
L+IA T +D G +T SA + V +N
Sbjct: 2628 RRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKN 2669
Score = 38.9 bits (89), Expect = 0.027
Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 10/104 (9%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWF------CEGKE--LHNTPDIQI 319
P P I EV EG+ V + ++ G P P + WF + KE L++T ++
Sbjct: 9742 PDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKL 9801
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
+ D TL+I ++ DTG YT A N G+ + + + G
Sbjct: 9802 VVD--DTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9843
Score = 38.9 bits (89), Expect = 0.027
Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 22/125 (17%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V GQ + + RV+G P + W ++G + ++Q PR L I E
Sbjct: 11548 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPR--------VELQIKEA 11599
Query: 512 FPEDAGIFTCSARNDYGSATSTA------------QLVVTSANTENC--SYESMGESNND 557
D G + SA+N G A +A L VT+ ENC S+E+ ++
Sbjct: 11600 VRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGS 11659
Query: 558 HFQHF 562
+F
Sbjct: 11660 EITNF 11664
Score = 38.9 bits (89), Expect = 0.027
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F TV G+ ++D G PTP ++W D P++ + EN L
Sbjct: 15776 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN-SLLT 15834
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
I+ D G Y TN AG+ +L ++V K
Sbjct: 15835 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15868
Score = 38.9 bits (89), Expect = 0.027
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 768 DVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ 827
D+ +E + P F Y + G + ++G PKP I W KDG + ++ +
Sbjct: 16853 DLVIEPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINVT 16907
Query: 828 RDLDGTCSLHTTASTLDDDGNYTIMAANPQGR 859
LD T +L + DD G Y I AN G+
Sbjct: 16908 DSLDLT-TLSIKETHKDDGGQYGITVANVVGQ 16938
Score = 38.9 bits (89), Expect = 0.027
Identities = 35/139 (25%), Positives = 50/139 (35%), Gaps = 24/139 (17%)
Query: 227 QGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGS 286
+ + E+ V P QDL V P +H PA G
Sbjct: 23338 RAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPA---------------GR 23382
Query: 287 RVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT----LIIAEAFEDDTGRY 342
V L + G P P WF G +L + + + + HT L I E DTG Y
Sbjct: 23383 PVELVIPIAGRPPPAASWFFAGSKLRESERVTV-----ETHTKVAKLTIRETTIRDTGEY 23437
Query: 343 TCLATNPSGSDTTSAEVFI 361
T N +G+ + + +V I
Sbjct: 23438 TLELKNVTGTTSETIKVII 23456
Score = 38.5 bits (88), Expect = 0.036
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKE-------LHNTPDIQIHCEGGDLHTLIIAEAFED 337
GS++ + + G PTP+ W +GK +H+ P+ + +II E
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9512
Query: 338 DTGRYTCLATNPSGSDTTSAEV 359
TG+Y+ A N +G T + V
Sbjct: 9513 HTGKYSITAKNKAGQKTANCRV 9534
Score = 38.5 bits (88), Expect = 0.036
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 13/129 (10%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLE---LVVAAKEAHKPPVFIE-KLQNTGVAD-GY 1025
+ +T A + IA N AG S E + + P + ++ K ++T + G
Sbjct: 15046 VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGE 15105
Query: 1026 PVRLECRVLGVPPPQIFWKKENESLTHSTD---RVSMHQDNHGYICLLIQGATKEDAGWY 1082
RLE V G PPP + W K+ + L + +++ N L+ + +T+ D+G Y
Sbjct: 15106 AFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN-----LVNKDSTRRDSGAY 15160
Query: 1083 TVSAKNEAG 1091
T++A N G
Sbjct: 15161 TLTATNPGG 15169
Score = 38.5 bits (88), Expect = 0.036
Identities = 37/159 (23%), Positives = 65/159 (40%), Gaps = 18/159 (11%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V G+ + ++G P P SW G +R +S + V L I T RD G
Sbjct: 23378 VPAGRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTVETHTKVAKLTIRETTIRDTGE 23436
Query: 982 YTCIATNRAGQNSFSLELVVAAKEAHKP-PVFIEKLQNTGVADGY-PVRLECRVLGVPPP 1039
YT N G S ++++++ K P+ I+++ T + + P L+ G P
Sbjct: 23437 YTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPL 23492
Query: 1040 QIF-----------WKKENESLTHSTDRVSMHQDNHGYI 1067
+ W +ES+T ST + + + + Y+
Sbjct: 23493 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYV 23531
Score = 38.1 bits (87), Expect = 0.046
Identities = 59/300 (19%), Positives = 106/300 (35%), Gaps = 48/300 (16%)
Query: 79 PSHKETKLGEHASRRPQDNRSTPVQPLAEKQTKSISSPVSKRKPAMSPL--LTRPSYIRS 136
P KE + + R+ + V+P K+ + + P P P+ + P+ +
Sbjct: 4569 PEPKEEVVLKSVLRKRPEEEEPKVEP---KKLEKVKKPAVPEPPPPKPVEEVEVPTVTKR 4625
Query: 137 LRKAE--------KRGAKTPSTNVKPKTPHQRKGGPQSQLCDKAANLIEELTSIFKAAKP 188
RK K P+ KPK + K + + + +T K
Sbjct: 4626 ERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKA 4685
Query: 189 RNRSPNGESSSPDSGYLS-PKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQ 247
++P E++ P PK PS + E ER PG+
Sbjct: 4686 EAKAPKEEAAKPKGPIKGVPKKTPSPI--------------EAERRKLRPGSG------- 4724
Query: 248 DLAVPHNRKSHPQPHSALHFPAAP-RFIQKLRSQEVAE----GSRVYLECRVTGNPTPRV 302
K + A P +F+++++ + E GS EC V+ + T
Sbjct: 4725 ------GEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPS-TAIT 4777
Query: 303 RWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
W +G + +P + +G D L I + D G YTC+ + T++A++ +E
Sbjct: 4778 TWMKDGSNIRESPKHRFIADGKD-RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 4836
Score = 38.1 bits (87), Expect = 0.046
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 8/114 (7%)
Query: 982 YTCIATNRAGQNSFS-LELVVAAKEAHKPPVFI---EKLQNTGVADGYPVRLECRVLGVP 1037
+ +A N AG++ + + V K+ +PP I + + G +RL + GVP
Sbjct: 10815 FRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVP 10874
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
P++ WKKE+ + R+ + L I+ A ED G Y+++ +N AG
Sbjct: 10875 FPKVTWKKEDRD-APTKARIDVTPVGSK---LEIRNAAHEDGGIYSLTVENPAG 10924
Score = 38.1 bits (87), Expect = 0.046
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G+ V L+ V G P P V W +G L I++ + +L TL + D+G
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQ-RNLCTLELFSVNRKDSGD 12993
Query: 342 YTCLATNPSGSDTTSAEV 359
YT A N SGS + + ++
Sbjct: 12994 YTITAENSSGSKSATIKL 13011
Score = 38.1 bits (87), Expect = 0.046
Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Query: 920 LTVQEGKLCRMDC-KVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
LT++ G ++ + G P P SW GK +RP ++ L I+ T +D
Sbjct: 14016 LTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKD 14074
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
AG YT ATN G +++ V PV I +
Sbjct: 14075 AGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNV 14112
Score = 38.1 bits (87), Expect = 0.046
Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ GS + L+ V G P P++ W KEL + + G T +I D+G+
Sbjct: 22687 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYT-GKRATAVIKFCDRSDSGK 22745
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SG+ S V
Sbjct: 22746 YTLTVKNASGTKAVSVMV 22763
Score = 37.7 bits (86), Expect = 0.061
Identities = 50/218 (22%), Positives = 81/218 (37%), Gaps = 46/218 (21%)
Query: 783 LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 842
L K+ EG V +V+ + W KDG+++ P SD I D L T
Sbjct: 2316 LSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQP-SDRVHIVIDKQSHMLL-IEDMT 2372
Query: 843 LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENE 902
+D GNY+ P +S +GR+ V +V D
Sbjct: 2373 KEDAGNYSFTI--PALGLSTSGRVSVYSV---------------------------DVIT 2403
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
P++ D+ V EG ++CKVS + W L+ + ++PD + +V+
Sbjct: 2404 PLK-------------DVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK 2450
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 1000
L+I + D G Y I + S+E +
Sbjct: 2451 -GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKI 2487
Score = 37.7 bits (86), Expect = 0.061
Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 8/87 (9%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G V L+ V G P V W + G+ ++ + ++ ++ +CTL +
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR--------NLCTLELFSV 12986
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVV 538
+D+G +T +A N GS ++T +L V
Sbjct: 12987 NRKDSGDYTITAENSSGSKSATIKLKV 13013
Score = 37.4 bits (85), Expect = 0.079
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWF--CEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDT 339
V G + LE V G P P V W + +L +P ++I D + +A D
Sbjct: 11841 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTR-ADSSKFSLTKAKRSDG 11899
Query: 340 GRYTCLATNPSGSDTTSAEV 359
G+Y ATN +GS A V
Sbjct: 11900 GKYVVTATNTAGSFVAYATV 11919
Score = 37.0 bits (84), Expect = 0.10
Identities = 47/218 (21%), Positives = 90/218 (41%), Gaps = 34/218 (15%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G+ V + V G P +++W + + I+ D + K+ S +E + L I +
Sbjct: 9038 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAK--TELSIPKA 9095
Query: 512 FPEDAGIFTCSARNDYGSA------------TSTAQLVVTSANTENC--SYESMGESNND 557
ED G +T +A N GS + L VT E+C ++++ ++
Sbjct: 9096 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGS 9155
Query: 558 HFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSR 617
H+ +++ AS+K +E ++V N A++ ++ + NG + R
Sbjct: 9156 EITHY-----VIDKRD---ASRKKAEWEEVTN-------TAVEKRYGIWKLIPNGQYEFR 9200
Query: 618 GVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKL 655
+N S++ V+ P + P P KPK+
Sbjct: 9201 --VRAVNKYGISDECKSDKVVIQDPYRLPGP-PGKPKV 9235
Score = 37.0 bits (84), Expect = 0.10
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL-IQGATKEDAGWY 1082
G +RL V G PPP+I W K N +L DR+ + + + L + K DAG Y
Sbjct: 13336 GVTMRLYVPVKGRPPPKITWSKPNVNL---RDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13392
Query: 1083 TVSAKNEAG 1091
++ +N G
Sbjct: 13393 ILTLENSCG 13401
Score = 37.0 bits (84), Expect = 0.10
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 923 QEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH-SLIIEPVTSRDAGI 981
+E R+ + G P P +SW+ P+ D+ ++ V + V+ +LI+ DAG
Sbjct: 13623 KENSNFRLKIPIKGKPAPSVSWKKGEDPLATDT--RVSVESSAVNTTLIVYDCQKSDAGK 13680
Query: 982 YTCIATNRAGQNSFSLELVVAAK 1004
YT N AG ++ + V K
Sbjct: 13681 YTITLKNVAGTKEGTISIKVVGK 13703
Score = 37.0 bits (84), Expect = 0.10
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQG 858
V+G P P + W KDGK++ + + D + +L ST D G YT+ A NP G
Sbjct: 15113 VSGRPPPTMEWSKDGKELEGTAKLEI--KIADFSTNLVNKDSTRRDSGAYTLTATNPGG 15169
Score = 37.0 bits (84), Expect = 0.10
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 10/121 (8%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ R++ V G P P + W K + +SA + + LI++ D
Sbjct: 17263 IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIE-ESARCEIKNTDFKALLIVKDAIRIDG 17321
Query: 980 GIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPP 1039
G Y A+N AG SF + + V + PP +Q TGV +C + PP
Sbjct: 17322 GQYILRASNVAGSKSFPVNVKVLDRPG--PPE--GPVQVTGVTSE-----KCSLTWSPPL 17372
Query: 1040 Q 1040
Q
Sbjct: 17373 Q 17373
Score = 37.0 bits (84), Expect = 0.10
Identities = 29/125 (23%), Positives = 57/125 (45%), Gaps = 3/125 (2%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNS-FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
I +T+ + ++ A N G++ L + V A++ P V +++
Sbjct: 18983 ISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKI 19042
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
+ G P + W+K+ ++L +T RV++ + L I+ A+KED G Y + N
Sbjct: 19043 DVPFKGRPQATVNWRKDGQTLKETT-RVNV-SSSKTVTSLSIKEASKEDVGTYELCVSNS 19100
Query: 1090 AGIVS 1094
AG ++
Sbjct: 19101 AGSIT 19105
Score = 37.0 bits (84), Expect = 0.10
Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 14/86 (16%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLT-----HSTDRVSMHQDNHGYICLLIQGAT 1075
V G +RL G P P W K + +L+ H+TD S L ++
Sbjct: 21997 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST---------LTVENCN 22047
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDV 1101
+ DAG YT++ +N +G S T + V
Sbjct: 22048 RNDAGKYTLTVENNSGSKSITFTVKV 22073
Score = 37.0 bits (84), Expect = 0.10
Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Query: 781 MKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA 840
M K + G PV +AG P P WF G ++ +S+ T++ L
Sbjct: 23371 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTVETHTK-VAKLTIRE 23428
Query: 841 STLDDDGNYTIMAANPQGRISCTGRLMV 868
+T+ D G YT+ N G S T ++++
Sbjct: 23429 TTIRDTGEYTLELKNVTGTTSETIKVII 23456
Score = 36.6 bits (83), Expect = 0.14
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 10/178 (5%)
Query: 193 PNGESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVP 252
P +SPD G+ N + L+ + + +++ E E V C Q+ + P
Sbjct: 12165 PKIADASPDEGW-KRCNAAAQLVRKEFTVTSLDENQEYEFRV-------CAQNQVGIGRP 12216
Query: 253 HNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELH 312
K +P L P + V G + L V G P P+V W G + +
Sbjct: 12217 AELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-N 12275
Query: 313 NTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSD 370
Q+ + L+I + DD+G+Y+ NP+G V + SD
Sbjct: 12276 VVRKGQVDLVD-TMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12332
Score = 36.6 bits (83), Expect = 0.14
Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P + ++ K ++T V + G RLE V G
Sbjct: 17221 FRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGK 17280
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
P P I W + ++ + S + D L+++ A + D G Y + A N AG S
Sbjct: 17281 PLPTIEWLRGDKEIEESARCEIKNTDFKA--LLIVKDAIRIDGGQYILRASNVAGSKSFP 17338
Query: 1097 ARLDV 1101
+ V
Sbjct: 17339 VNVKV 17343
Score = 36.6 bits (83), Expect = 0.14
Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
G+ V L ++G P P + W+ + KEL + + DL +++I +A ++G Y
Sbjct: 20515 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRLNSGCYEL 20573
Query: 345 LATNPSGSDTTSAEVFI 361
N GS + + V I
Sbjct: 20574 KLRNAMGSASATIRVQI 20590
Score = 36.6 bits (83), Expect = 0.14
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 5/103 (4%)
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHK 958
DEN P F +F L ++ G+ R+ V G P P ++W DG + +
Sbjct: 21579 DENVPPIVEFGPEYF----DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMNM 21633
Query: 959 MLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+ G SL + T G+YT A N +G +++ V
Sbjct: 21634 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21676
Score = 36.6 bits (83), Expect = 0.14
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC-LLIQGATKEDA 1079
V G PV L + G PPP W L S +RV++ + H + L I+ T D
Sbjct: 23378 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRES-ERVTV--ETHTKVAKLTIRETTIRDT 23434
Query: 1080 GWYTVSAKNEAGIVSCTARL 1099
G YT+ KN G S T ++
Sbjct: 23435 GEYTLELKNVTGTTSETIKV 23454
Score = 36.6 bits (83), Expect = 0.14
Identities = 20/97 (20%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V++G + R+ + G P P W +G+ + S M+ L+I+ D+G
Sbjct: 23776 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI---SKRAMIATSETHTELVIKEADRGDSGT 23832
Query: 982 YTCIATNRAGQNSFSLEL-VVAAKEAHKPPVFIEKLQ 1017
Y + N+ G+ + +++ V+ + + + P+ + +Q
Sbjct: 23833 YDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQ 23869
Score = 36.2 bits (82), Expect = 0.18
Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 6/80 (7%)
Query: 284 EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC-EGGDLHTLIIAEA-FEDDTGR 341
EG V+L +T V W+ E K + + D + C + + +TL+I + ED G
Sbjct: 4381 EGDIVHLTTSITN--AKEVNWYFENKLVPS--DEKFKCLQDQNTYTLVIDKVNTEDHQGE 4436
Query: 342 YTCLATNPSGSDTTSAEVFI 361
Y C A N SG TSA++ +
Sbjct: 4437 YVCEALNDSGKTATSAKLTV 4456
Score = 36.2 bits (82), Expect = 0.18
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 1/86 (1%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
++ L V G+++ L VTG P P++ W L I I T+ I +
Sbjct: 7322 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVD 7380
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAEV 359
+ DTG Y A N G T EV
Sbjct: 7381 SKRSDTGTYIIEAVNVCGRATAVVEV 7406
Score = 36.2 bits (82), Expect = 0.18
Identities = 39/169 (23%), Positives = 59/169 (34%), Gaps = 22/169 (13%)
Query: 824 YTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG 883
Y + + L GT + YT+ R +L V AVN G P +
Sbjct: 8664 YFVDKQLVGTNEWSRCTEKMIKVRQYTVKEI----REGADYKLRVSAVNAAGEGPPGETQ 8719
Query: 884 HPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLS 943
V P+ D + G + + GK R+ V+G P P
Sbjct: 8720 PVTVAEPQEPPAVELD--------------VSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8765
Query: 944 WQLDGKPVRPDSAHKMLVRENGVHS-LIIEPVTSRDAGIYTCIATNRAG 991
W + + D ++++ G S LII+ +D G Y ATN G
Sbjct: 8766 WTKEEGELDKD---RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8811
Score = 36.2 bits (82), Expect = 0.18
Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 9/123 (7%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKK 1045
A N AG + S + + P I+ + V +G V + ++ GVP P + W K
Sbjct: 9721 AVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 9780
Query: 1046 -------ENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTAR 1098
E + + T + D+ L+I + + D G YT++A N G S R
Sbjct: 9781 APPKKPDNKEPVLYDTHVNKLVVDDT--CTLVIPQSRRSDTGLYTITAVNNLGTASKEMR 9838
Query: 1099 LDV 1101
L+V
Sbjct: 9839 LNV 9841
Score = 36.2 bits (82), Expect = 0.18
Identities = 20/94 (21%), Positives = 36/94 (38%), Gaps = 1/94 (1%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P+ ++ + V G+ V + G P P +W +G E+ + +
Sbjct: 11136 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS-S 11194
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
L I DTG Y +N +GS T + + +
Sbjct: 11195 VLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 36.2 bits (82), Expect = 0.18
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G P ++ + G P P++ WK E E TDRVS+ L ++ + + D+G Y
Sbjct: 22290 GSPFTIDVPISGRPAPKVTWKLE-EMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYF 22347
Query: 1084 VSAKNEAGI 1092
++ +N AG+
Sbjct: 22348 LTLENTAGV 22356
Score = 35.8 bits (81), Expect = 0.23
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A F++ L Q V E C+++ V+W+ G+E+ + + G +H
Sbjct: 6449 APTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKKYKFE-KDGSIHR 6506
Query: 329 LIIAEAFEDDTGRYTC 344
LII + DD Y C
Sbjct: 6507 LIIKDCRLDDECEYAC 6522
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 11/127 (8%)
Query: 732 NQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEG 791
NQEY+ C Q + I E + + ++ ++ ++ M ++ G
Sbjct: 12198 NQEYEFRVCAQNQVG-IGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRA-------G 12249
Query: 792 MPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTI 851
P+ V G P PK+ W K G + + +D L ST DD G Y++
Sbjct: 12250 CPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL---VDTMAFLVIPNSTRDDSGKYSL 12306
Query: 852 MAANPQG 858
NP G
Sbjct: 12307 TLVNPAG 12313
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 12/109 (11%)
Query: 992 QNSFSLELVVAAKEAHKPPVFIEKLQN---------TGVADGYPVRLECRVLGVPPPQIF 1042
QN + KEA KP +E + V G P+RL V G P P++
Sbjct: 12208 QNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVT 12267
Query: 1043 WKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
W+K +V + D + L+I +T++D+G Y+++ N AG
Sbjct: 12268 WRKVGIDNVVRKGQVDL-VDTMAF--LVIPNSTRDDSGKYSLTLVNPAG 12313
Score = 35.8 bits (81), Expect = 0.23
Identities = 19/82 (23%), Positives = 35/82 (42%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ ++ + G P PD+ W DGK + +A + +L+++ D
Sbjct: 18345 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18404
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y +N G S + + V
Sbjct: 18405 GQYILKLSNVGGTKSIPITVKV 18426
Score = 35.8 bits (81), Expect = 0.23
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V+ G ++D +SG P P ++ DG P++ + + + E VT+ DAG
Sbjct: 20116 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTA-DAGR 20174
Query: 982 YTCIATNRAGQNSFSLELVV 1001
Y A N +G + +VV
Sbjct: 20175 YEITAANSSGTTKAFINIVV 20194
Score = 35.4 bits (80), Expect = 0.30
Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 986 ATNRAGQNSF---SLELVVAAKEAHKPPVFIEKLQNTGV---ADGYPVRLECRVLGVPPP 1039
A N AG S S E ++ E P + ++ G+ A V +LG P P
Sbjct: 13978 AKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLP 14037
Query: 1040 QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
+ W K + + S ++ L I+ AT++DAG YT++A N G
Sbjct: 14038 KSSWSKAGKDIRPSD--ITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14087
Score = 35.4 bits (80), Expect = 0.30
Identities = 24/60 (40%), Positives = 27/60 (45%), Gaps = 4/60 (6%)
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA-STLDDDGNYTIMAANPQG 858
+ G P PK W K GK I P Q T S+ T +T D G YTI A NP G
Sbjct: 14031 ILGKPLPKSSWSKAGKDIRPSD---ITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14087
Score = 35.4 bits (80), Expect = 0.30
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V G ++ + G P P ++W +EL NT ++I + D T L + +A D+G
Sbjct: 16183 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEI--KSTDFATSLSVKDAVRVDSG 16240
Query: 341 RYTCLATNPSGSDTTSAEV 359
Y A N +G + + V
Sbjct: 16241 NYILKAKNVAGERSVTVNV 16259
Score = 35.4 bits (80), Expect = 0.30
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V G LE V G P P + W KE+ + +I + D LI+ +A D G
Sbjct: 17265 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI--KNTDFKALLIVKDAIRIDGG 17322
Query: 341 RYTCLATNPSGSDTTSAEV 359
+Y A+N +GS + V
Sbjct: 17323 QYILRASNVAGSKSFPVNV 17341
Score = 35.4 bits (80), Expect = 0.30
Identities = 20/85 (23%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+T + G +D +SG P P ++W+L+ ++ + ++ +L ++ D+
Sbjct: 22285 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRT-TLTVKDSMRGDS 22343
Query: 980 GIYTCIATNRAGQNSFSLELVVAAK 1004
G Y N AG +FS+ +VV +
Sbjct: 22344 GRYFLTLENTAGVKTFSVTVVVIGR 22368
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V EG ++ + P P V W +GKE+ + + + + H L + ++ D G
Sbjct: 8026 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGI 8084
Query: 342 YTCLATNPSGSDTTSAEVFIEG 363
YT N GS T S V + G
Sbjct: 8085 YTITLENKLGSATASINVKVIG 8106
Score = 35.0 bits (79), Expect = 0.39
Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS-LIIEPVTSRDAG 980
++ G R+ + G+P P ++W+ + + D+ K + V S L I D G
Sbjct: 10858 IKVGDTLRLSAIIKGVPFPKVTWKKEDR----DAPTKARIDVTPVGSKLEIRNAAHEDGG 10913
Query: 981 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIE 1014
IY+ N AG + S++++V K PP +E
Sbjct: 10914 IYSLTVENPAGSKTVSVKVLVLDKPG--PPRDLE 10945
Score = 35.0 bits (79), Expect = 0.39
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 17/80 (21%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH--------SLII 971
+TV+ G+ R+ +V G P PD++W +G K+LVRE V L I
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEG---------KVLVREKRVDLIQDLPRVELQI 11596
Query: 972 EPVTSRDAGIYTCIATNRAG 991
+ D G Y A N +G
Sbjct: 11597 KEAVRADHGKYIISAKNSSG 11616
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F + V G + ++ G PTP V W + L T +++ E + ++L+
Sbjct: 15776 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQT--TRVNAESTENNSLL 15833
Query: 331 -IAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
I +A +D G Y TN +G + V +
Sbjct: 15834 TIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15865
Score = 35.0 bits (79), Expect = 0.39
Identities = 21/71 (29%), Positives = 29/71 (40%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G LE + G P P V W +GKEL T TL++ + D G+
Sbjct: 18347 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406
Query: 342 YTCLATNPSGS 352
Y +N G+
Sbjct: 18407 YILKLSNVGGT 18417
Score = 35.0 bits (79), Expect = 0.39
Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 4/118 (3%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGVPPPQIFW 1043
A + + S S ++ + P V ++ K ++ V G +++ + G P P I W
Sbjct: 19392 AADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISW 19451
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
K+ + + DNH L ++ + D G Y ++ KN AG S V
Sbjct: 19452 AKDGIEIEERARTEIISTDNH--TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19507
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V +G + L + G P P +W EG+++ I + HT L+I EA D+G
Sbjct: 23776 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIAT----SETHTELVIKEADRGDSG 23831
Query: 341 RYTCLATNPSGSDTTSAEVFIEGASST 367
Y + N G +V + G+ ++
Sbjct: 23832 TYDLVLENKCGKKAVYIKVRVIGSPNS 23858
Score = 34.7 bits (78), Expect = 0.51
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 10/94 (10%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTL-DDDGNY 849
G V F + G P P W DG +I +HYT+ + D S+ T + L D G Y
Sbjct: 11153 GTTVRFPAIIRGVPVPTAKWTTDGSEIK-TDEHYTV--ETDNFSSVLTIKNCLRRDTGEY 11209
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG 883
I +N G + L V V P P+G
Sbjct: 11210 QITVSNAAGSKTVAVHLTVLDV------PGPPTG 11237
Score = 34.7 bits (78), Expect = 0.51
Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G + + RV G P P + W EGK L + + + L I EA D G+
Sbjct: 11548 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL-IQDLPRVELQIKEAVRADHGK 11606
Query: 342 YTCLATNPSGSDTTSAEV 359
Y A N SG SA V
Sbjct: 11607 YIISAKNSSGHAQGSAIV 11624
Score = 34.7 bits (78), Expect = 0.51
Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G + RV G P+P I W K+GK + + + +DL L + D G Y
Sbjct: 11551 GQTIRILARVKGRPEPDITWTKEGK-VLVREKRVDLIQDLP-RVELQIKEAVRADHGKYI 11608
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
I A N G G +V +++ G
Sbjct: 11609 ISAKNSSGH--AQGSAIVNVLDRPG 11631
Score = 34.7 bits (78), Expect = 0.51
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Query: 294 VTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSD 353
+ G P P+ W GK++ + QI L I A D G YT ATNP G+
Sbjct: 14031 ILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKDAGEYTITATNPFGTK 14089
Query: 354 TTSAEVFI 361
+V +
Sbjct: 14090 VEHVKVTV 14097
Score = 34.7 bits (78), Expect = 0.51
Identities = 27/101 (26%), Positives = 52/101 (51%), Gaps = 7/101 (6%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSW-QLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
+ ++ G R+ + G PTP++ W ++DG+ +R D+A ++ + SL+++ V D
Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGE-IR-DAA--IIDVTSSFTSLVLDNVNRYD 16635
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT 1019
+G YT N +G S + V + PPV ++ + T
Sbjct: 16636 SGKYTLTLENSSGTK--SAFVTVRVLDTPSPPVNLKVTEIT 16674
Score = 34.7 bits (78), Expect = 0.51
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 917 PG-DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
PG +TV+ G ++ G P P +SW DG P++ + EN + +L I+
Sbjct: 21197 PGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAK 21255
Query: 976 SRDAGIYTCIATN 988
G YT I N
Sbjct: 21256 KEHGGKYTVILDN 21268
Score = 34.3 bits (77), Expect = 0.67
Identities = 26/129 (20%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Query: 966 VHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF---IEKLQNTGVA 1022
+ ++ + +++ + A N AG ++ V E P F E + V
Sbjct: 14358 ITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVR 14417
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
G +R+ + G P P++ W K+N +L + + ++ + L+I + D G +
Sbjct: 14418 AGLSIRIFVPIKGRPAPEVTWTKDNINLKNRAN----IENTESFTLLIIPECNRYDTGKF 14473
Query: 1083 TVSAKNEAG 1091
++ +N AG
Sbjct: 14474 VMTIENPAG 14482
Score = 33.9 bits (76), Expect = 0.88
Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 3/92 (3%)
Query: 272 RFIQKLRSQ-EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
RF++ L + V +G +YL C + N V W +GK + P + G + L
Sbjct: 4841 RFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALT 4898
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
I +A + D G YT N + + +S +E
Sbjct: 4899 INDADDTDAGTYTVTVENANNLECSSCVKVVE 4930
Score = 33.9 bits (76), Expect = 0.88
Identities = 28/165 (16%), Positives = 63/165 (38%), Gaps = 15/165 (9%)
Query: 942 LSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN--SFSLEL 999
+++ L+ + + + HK+ ++ + D Y A N GQ SF +
Sbjct: 10377 INYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP 10436
Query: 1000 VVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESL--------- 1050
+ E P + ++ + G L R G P P++ W K+ +
Sbjct: 10437 ITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK 10496
Query: 1051 ----THSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
T + +++ + + G C++++ +T G+ V+ + G
Sbjct: 10497 TTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG 10541
Score = 33.9 bits (76), Expect = 0.88
Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS-LIIE 972
L+ G LTV+ G R++ V G P P+++W D + ++ + S +
Sbjct: 11833 LKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT 11892
Query: 973 PVTSRDAGIYTCIATNRAG 991
D G Y ATN AG
Sbjct: 11893 KAKRSDGGKYVVTATNTAG 11911
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 3/74 (4%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFED 337
R+ V G + + + G P P V W + L N +I+ + E L LII E
Sbjct: 14412 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE-NTESFTL--LIIPECNRY 14468
Query: 338 DTGRYTCLATNPSG 351
DTG++ NP+G
Sbjct: 14469 DTGKFVMTIENPAG 14482
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 1027 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 1086
+RL + G P P++ W+K L TDR + + + L+I T+ D+G Y ++
Sbjct: 18753 LRLFVTIKGRPEPEVKWEKAEGIL---TDRAQI-EVTSSFTMLVIDNVTRFDSGRYNLTL 18808
Query: 1087 KNEAGIVSCTARLDVYI 1103
+N +G S TA ++V +
Sbjct: 18809 ENNSG--SKTAFVNVRV 18823
Score = 33.9 bits (76), Expect = 0.88
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V GS + ++ ++G P P+V +G L T +L T+ + E+ D GR
Sbjct: 20116 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL-TINLKESVTADAGR 20174
Query: 342 YTCLATNPSGSDTTSAEVFI 361
Y A N SG TT A + I
Sbjct: 20175 YEITAANSSG--TTKAFINI 20192
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 777 PFFEMKLKHYKIFE---GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
P ++ L++ ++ + G V ++G P P I W+KD K++ + ++ D
Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA-LVCVENTTDLA 20556
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
L A L + G Y + N G S T R+ +
Sbjct: 20557 SILIKDADRL-NSGCYELKLRNAMGSASATIRVQI 20590
Score = 33.9 bits (76), Expect = 0.88
Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 6/110 (5%)
Query: 986 ATNRAGQNS-FSLELVVAAKEA-HKPPVFIEKLQNTGVAD--GYPVRLECRVLGVPPPQI 1041
A N AGQ + V AK+ P + ++ T V G V++ G PPP +
Sbjct: 20872 AVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTV 20931
Query: 1042 FWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
W+K+ ++L S R S+ + + L I T+ D G Y ++ +N G
Sbjct: 20932 TWRKDEKNL-GSDARYSIENTDSSSL-LTIPQVTRNDTGKYILTIENGVG 20979
Score = 33.9 bits (76), Expect = 0.88
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
+ G+ + ++ V+G P +V WF+ G EI+ + I + +L + +
Sbjct: 21598 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST--------SLFVRDA 21649
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVV 538
+ G++T A+N GSA + ++ V
Sbjct: 21650 TRDHRGVYTVEAKNASGSAKAEIKVKV 21676
Score = 33.5 bits (75), Expect = 1.1
Identities = 31/124 (25%), Positives = 49/124 (39%), Gaps = 6/124 (4%)
Query: 982 YTCIATNRAGQNSFS--LELVVAAKEAHKPPVFIEK--LQNTGVADGYPVRLECRVLGVP 1037
Y A NR G + S E + A P +F++ L V G + L V G P
Sbjct: 7287 YRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 7346
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 1097
P+I W K + L D+ ++ + I + + D G Y + A N G +
Sbjct: 7347 EPKITWTKADMIL--KQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVV 7404
Query: 1098 RLDV 1101
++V
Sbjct: 7405 EVNV 7408
Score = 33.5 bits (75), Expect = 1.1
Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 6/84 (7%)
Query: 914 LQAPGD-LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS---- 968
L GD + V+ G+ + V+GLP P + W + + + + +E S
Sbjct: 9029 LSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKT 9088
Query: 969 -LIIEPVTSRDAGIYTCIATNRAG 991
L I D G YT A+NR G
Sbjct: 9089 ELSIPKAVREDKGTYTVTASNRLG 9112
Score = 33.5 bits (75), Expect = 1.1
Identities = 17/73 (23%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G + R+ VSG P P ++W ++ + + ++ + + S++I+
Sbjct: 10162 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS---SMVIKNCQRSHQ 10218
Query: 980 GIYTCIATNRAGQ 992
G+Y+ +A N AG+
Sbjct: 10219 GVYSLLAKNEAGE 10231
Score = 33.5 bits (75), Expect = 1.1
Identities = 49/202 (24%), Positives = 82/202 (40%), Gaps = 21/202 (10%)
Query: 901 NEPIQERFFRPHFLQAPG-DLTV--------QEGKLCRMDCKVSGLPTPDLSWQLDGKPV 951
NEP+Q + L+AP DL V + G+ ++ G P P ++W+ D K +
Sbjct: 20885 NEPVQAK----DILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNL 20940
Query: 952 RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV 1011
D+ + + + L I VT D G Y N G+ S + + P
Sbjct: 20941 GSDARYS-IENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSS----TVSVKVLDTPA 20995
Query: 1012 FIEKLQNTGVADGYPVRL-ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
+KLQ V+ G L + ++ P I + E T T V H+ + L+
Sbjct: 20996 ACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI 21055
Query: 1071 IQGATKEDAGWYTVSAKNEAGI 1092
+++ ++ V A+NE GI
Sbjct: 21056 --DLSEKTPFFFRVLAENEIGI 21075
Score = 33.5 bits (75), Expect = 1.1
Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 8/137 (5%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELV--VAAKEAHKPPVFIEKLQNTG----VADG 1024
+ ++ D + +A N AG S E V ++ + PP + G + G
Sbjct: 22631 VTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAG 22690
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
+ L+ V G P P+I W K ++ L ++VS+ Q +I+ + D+G YT+
Sbjct: 22691 SDLVLDAAVGGKPEPKIIWTKGDKEL-DLCEKVSL-QYTGKRATAVIKFCDRSDSGKYTL 22748
Query: 1085 SAKNEAGIVSCTARLDV 1101
+ KN +G + + + V
Sbjct: 22749 TVKNASGTKAVSVMVKV 22765
Score = 33.1 bits (74), Expect = 1.5
Identities = 31/130 (23%), Positives = 53/130 (40%), Gaps = 18/130 (13%)
Query: 986 ATNRAGQN--SFSLELVVAAKEAHKPPVFIEKLQNTGVAD------GYPVRLECRVLGVP 1037
A N AG++ S + + A +P VFI+ G D G +R+ + G P
Sbjct: 9411 AVNEAGESEPSDTTGEIPATDIQEEPEVFID----IGAQDCLVCKAGSQIRIPAVIKGRP 9466
Query: 1038 PPQIFW------KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
P+ W KK + H + + ++I + G Y+++AKN+AG
Sbjct: 9467 TPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAG 9526
Query: 1092 IVSCTARLDV 1101
+ R+ V
Sbjct: 9527 QKTANCRVKV 9536
Score = 33.1 bits (74), Expect = 1.5
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 12/82 (14%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESL----THSTDRVSMHQDNHGYICLLIQGATKEDA 1079
G +R+ V G PPP + W +L T T +S ++I+ +
Sbjct: 10167 GGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSS--------MVIKNCQRSHQ 10218
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G Y++ AKNEAG T +DV
Sbjct: 10219 GVYSLLAKNEAGERKKTIIVDV 10240
Score = 33.1 bits (74), Expect = 1.5
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 284 EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTGRY 342
E S L+ + G P P V W +G++ T D ++ E ++T LI+ + + D G+Y
Sbjct: 13624 ENSNFRLKIPIKGKPAPSVSWK-KGEDPLAT-DTRVSVESSAVNTTLIVYDCQKSDAGKY 13681
Query: 343 TCLATNPSGSDTTSAEVFIEG 363
T N +G+ + + + G
Sbjct: 13682 TITLKNVAGTKEGTISIKVVG 13702
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
+V GQ + +E + G P + W + G ++ + + + ++ TL I E
Sbjct: 16868 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV--------TDSLDLTTLSIKE 16919
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLV 537
T +D G + + N G T++ ++V
Sbjct: 16920 THKDDGGQYGITVANVVGQKTASIEIV 16946
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
V G R+ G P P+I W +E TD+V + + Y L I + DAG
Sbjct: 17664 VRAGGSARIHIPFKGRPTPEITWSREEGEF---TDKVQI-EKGVNYTQLSIDNCDRNDAG 17719
Query: 1081 WYTVSAKNEAGIVSCTARLDV 1101
Y + +N +G S + V
Sbjct: 17720 KYILKLENSSGSKSAFVTVKV 17740
Score = 33.1 bits (74), Expect = 1.5
Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 296 GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTT 355
G P V W +G+ L T + + + +L I EA ++D G Y +N +GS T
Sbjct: 19048 GRPQATVNWRKDGQTLKETTRVNVS-SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 19106
Query: 356 SAEVFI 361
+ +
Sbjct: 19107 PITIIV 19112
Score = 32.7 bits (73), Expect = 2.0
Identities = 66/322 (20%), Positives = 121/322 (37%), Gaps = 62/322 (19%)
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
+A F K ++ +I EG F C ++ P + W +D K + D Y + D
Sbjct: 6178 LAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLE-SGDKYDVIADGKKRV 6235
Query: 835 SLHTTASTLDDDGNYTIM--AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 892
L +TL D G Y +M AA ++ +L +
Sbjct: 6236 -LVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVV---------------------- 6272
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
P++ D V+E + +C+V+ W + + +
Sbjct: 6273 ----------PLK-------------DTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIF 6308
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF 1012
DS+ ++++++ V++L I D Y TN G+N S ++ +E +
Sbjct: 6309 -DSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLR---I 6364
Query: 1013 IEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
+E L++ + V C+V L V + W K E + +RVS D + ++ L
Sbjct: 6365 VEPLKDIETMEKKSVTFWCKVNRLNV---TLKWTKNGEEVPFD-NRVSYRVDKYKHM-LT 6419
Query: 1071 IQGATKEDAGWYTVSAKNEAGI 1092
I+ D G Y V+A + +
Sbjct: 6420 IKDCGFPDEGEYIVTAGQDKSV 6441
Score = 32.7 bits (73), Expect = 2.0
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD-IQIHCE---GGDLHT-LIIAEAF 335
+V G V++ VTG P P++ W + D +QI E + T L I +A
Sbjct: 9037 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9096
Query: 336 EDDTGRYTCLATNPSGS 352
+D G YT A+N GS
Sbjct: 9097 REDKGTYTVTASNRLGS 9113
Score = 32.7 bits (73), Expect = 2.0
Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ ++D + G P P + W + G ++A + + SL ++ D+
Sbjct: 16181 IVVHAGESFKVDADIYGKPIPTIQW-IKGDQELSNTARLEIKSTDFATSLSVKDAVRVDS 16239
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y A N AG+ S ++ + V
Sbjct: 16240 GNYILKAKNVAGERSVTVNVKV 16261
Score = 32.7 bits (73), Expect = 2.0
Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G+ V LE G P P I W K+ L S I L I+ A KE G YT
Sbjct: 21206 GHNVHLELPYKGKPKPSISWLKDGLPLKES--EFVRFSKTENKITLSIKNAKKEHGGKYT 21263
Query: 1084 VSAKN 1088
V N
Sbjct: 21264 VILDN 21268
Score = 32.3 bits (72), Expect = 2.5
Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 271 PRFIQKLRSQEVA---EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
PR + ++ ++V G + + + G P P + W +G E+ +I D H
Sbjct: 19415 PRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI--ISTDNH 19472
Query: 328 TLI-IAEAFEDDTGRYTCLATNPSGS 352
TL+ + + DTG+Y N +G+
Sbjct: 19473 TLLTVKDCIRRDTGQYVLTLKNVAGT 19498
Score = 32.3 bits (72), Expect = 2.5
Identities = 22/105 (20%), Positives = 47/105 (44%), Gaps = 11/105 (10%)
Query: 437 AYFPPVFTKELQNTAVAE---GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKK 493
+Y PV L+ T V + G V L + G P ++W++ E+Q + +
Sbjct: 20494 SYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCV---- 20549
Query: 494 PRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ +++I + ++G + RN GSA++T ++ +
Sbjct: 20550 ----ENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 20590
Score = 32.3 bits (72), Expect = 2.5
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 918 GDL-TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTS 976
GDL T++ G +D V G P P + W K + D K+ ++ G + +
Sbjct: 22682 GDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCD 22739
Query: 977 R-DAGIYTCIATNRAGQNSFSLELVV 1001
R D+G YT N +G + S+ + V
Sbjct: 22740 RSDSGKYTLTVKNASGTKAVSVMVKV 22765
Score = 32.0 bits (71), Expect = 3.3
Identities = 49/236 (20%), Positives = 90/236 (38%), Gaps = 26/236 (11%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+ I+ LR E V E ++ + V W + KE+ + +I G ++ L +
Sbjct: 2488 KIIRGLRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHG-KIYKLTV 2545
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGAS-------STDSDSESLAFKSRAGAMP 384
+DD G+YT A G + TS ++ + G + T ++S+ F+ A P
Sbjct: 2546 LNMMKDDEGKYTFYA----GENMTSGKLTVAGGAISKPLTDQTVAESQEAVFECEV-ANP 2600
Query: 385 QAQ----KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFP 440
++ + + LT S G +I + ++ Y + + T+
Sbjct: 2601 DSKGEWLRDGKHLPLTNNIRSESDGHKRRLI----IAATKLDDIGEYTYKVATSKTSAKL 2656
Query: 441 PV----FTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
V K L+N V E Q V + VQW + G ++ + + I K
Sbjct: 2657 KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVK 2712
Score = 32.0 bits (71), Expect = 3.3
Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G + L + G PTP V+W GK D I +L++ D+G+
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKW---GKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGK 16638
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SG+ + V
Sbjct: 16639 YTLTLENSSGTKSAFVTV 16656
Score = 32.0 bits (71), Expect = 3.3
Identities = 30/118 (25%), Positives = 44/118 (37%), Gaps = 6/118 (5%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
+P L P + + V G + G PTP + W E E T +QI
Sbjct: 17642 KPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQI 17699
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFK 377
+G + L I +D G+Y N SGS + V + T ++LA K
Sbjct: 17700 E-KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV---LDTPGPPQNLAVK 17753
Score = 32.0 bits (71), Expect = 3.3
Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P ++ K ++ V G LE + G
Sbjct: 18303 FRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGK 18362
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 1094
P P + W K+ + L + R+ + + L+++ + D G Y + N G S
Sbjct: 18363 PIPDVVWSKDGKELEETAARMEI-KSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18419
Score = 31.6 bits (70), Expect = 4.3
Identities = 20/88 (22%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
++ G+ + +E V G P + W + G ++ + + E L I E
Sbjct: 17950 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV--------EETATSTVLHIKE 18001
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVV 538
+D G +T +A N G+AT ++V
Sbjct: 18002 GNKDDFGKYTVTATNSAGTATENLSVIV 18029
Score = 31.6 bits (70), Expect = 4.3
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
G V+LE G P P + W +G L + ++ + TL I A ++ G+YT
Sbjct: 21206 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAKKEHGGKYTV 21264
Query: 345 LATN 348
+ N
Sbjct: 21265 ILDN 21268
Score = 31.6 bits (70), Expect = 4.3
Identities = 22/80 (27%), Positives = 31/80 (38%), Gaps = 3/80 (3%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V+ G R+ G PTP W KP S + + +L +E DAG
Sbjct: 21997 VRAGASIRLFIAYQGRPTPTAVWS---KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGK 22053
Query: 982 YTCIATNRAGQNSFSLELVV 1001
YT N +G S + + V
Sbjct: 22054 YTLTVENNSGSKSITFTVKV 22073
Score = 31.6 bits (70), Expect = 4.3
Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G+ + L G PTP W L DI TL + +D G+
Sbjct: 21997 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT---DSFSTLTVENCNRNDAGK 22053
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SGS + + V
Sbjct: 22054 YTLTVENNSGSKSITFTV 22071
Score = 31.6 bits (70), Expect = 4.3
Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 9/112 (8%)
Query: 770 PVENGMAPFFEMK---LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTI 826
PVE P E+ K I G + V+G P P I W K G ++ ++ I
Sbjct: 23065 PVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA----I 23120
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
+ L D G YTI A N G+ S T ++V+ + G P
Sbjct: 23121 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSAT--VLVKVYDTPGPCP 23170
Score = 31.6 bits (70), Expect = 4.3
Identities = 21/94 (22%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 446 ELQNTAVAEGQVVVLECRVRGAPP-LQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
++ + EG V C++ QV W+ ++++S + I + + +
Sbjct: 25201 QIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE--------DGVA 25252
Query: 505 TLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L + + D G + C NDYG +S A+L V
Sbjct: 25253 ILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25286
Score = 31.2 bits (69), Expect = 5.7
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
A FI K ++ E+ EG + C ++ P V+W + K L + + + G L
Sbjct: 6179 AAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIAD-GKKRVL 6236
Query: 330 IIAEAFEDDTGRYTCL 345
++ +A D G Y +
Sbjct: 6237 VVKDATLQDMGTYVVM 6252
Score = 31.2 bits (69), Expect = 5.7
Identities = 18/69 (26%), Positives = 29/69 (42%), Gaps = 5/69 (7%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P+T PK + WFK+ + +S K+ T ++ S + D G Y
Sbjct: 6642 GKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQ-----TSFRILEAKKGDKGRYK 6696
Query: 851 IMAANPQGR 859
I+ N G+
Sbjct: 6697 IVLQNKHGK 6705
Score = 31.2 bits (69), Expect = 5.7
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G+ VLE +RG P V W + G E++++ + + +ST + TLV+ +
Sbjct: 18347 VHAGETFVLEADIRGKPIPDVVWSKDGKELEET----AARMEIKSTIQK---TTLVVKDC 18399
Query: 512 FPEDAGIFTCSARNDYGS 529
D G + N G+
Sbjct: 18400 IRTDGGQYILKLSNVGGT 18417
Score = 31.2 bits (69), Expect = 5.7
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G+ + L V+G P P + W +G +L + I E L LI+ + D G+
Sbjct: 23086 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDT-TESYSL--LIVDKVNRYDAGK 23142
Query: 342 YTCLATNPSGSDTTSAEV 359
YT A N SG + + V
Sbjct: 23143 YTIEAENQSGKKSATVLV 23160
Score = 31.2 bits (69), Expect = 5.7
Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 7/114 (6%)
Query: 254 NRKSHPQPHSALHFPAAPRFIQKLRSQEV---AEGSRVYLECRVTGNPTPRVRWFCEGKE 310
N + S L A P+F +E A GS + L G P P + WF K
Sbjct: 24237 NEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKL 24296
Query: 311 LHNTPDIQIHCEGGDLHTLIIAEAFEDDT--GRYTCLATNPSGSDTTSAEVFIE 362
L N+ +I I E + +T ++ + + T G+Y +N G+ +V I+
Sbjct: 24297 LQNSENITI--ENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24348
Score = 30.8 bits (68), Expect = 7.4
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Query: 433 GTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
G + Y V T L++ V EG VLEC+V V+W+ +I+ PD R+ Q
Sbjct: 2392 GRVSVYSVDVITP-LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIK--PDDRV-QA 2447
Query: 493 KPRSTAEPEEICTLVIAETFPEDAG 517
+ T + LVI T D G
Sbjct: 2448 IVKGTKQ-----RLVINRTHASDEG 2467
Score = 30.8 bits (68), Expect = 7.4
Identities = 24/95 (25%), Positives = 34/95 (35%), Gaps = 10/95 (10%)
Query: 445 KELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
K ++ V G V +RG P +W GSEI+ + T E +
Sbjct: 11143 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHY---------TVETDNFS 11193
Query: 505 T-LVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ L I D G + + N GS T L V
Sbjct: 11194 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 30.8 bits (68), Expect = 7.4
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 8/76 (10%)
Query: 455 GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPE 514
G+ LE V G PP ++W + G E++ + I + LV ++
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEI--------KIADFSTNLVNKDSTRR 15155
Query: 515 DAGIFTCSARNDYGSA 530
D+G +T +A N G A
Sbjct: 15156 DSGAYTLTATNPGGFA 15171
Score = 30.8 bits (68), Expect = 7.4
Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 9/98 (9%)
Query: 1003 AKEAHKPPVF---IEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSM 1059
AKE + P+F E + V G + G P P + W K + L R
Sbjct: 19805 AKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-----RTRA 19859
Query: 1060 HQDN-HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
+ D L I+ A + D+G YT++ +N S T
Sbjct: 19860 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT 19897
Score = 30.4 bits (67), Expect = 9.7
Identities = 20/94 (21%), Positives = 40/94 (42%), Gaps = 8/94 (8%)
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
+ + G+ + +E V G P +W + E+ S + + S L+
Sbjct: 12534 EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI--------LI 12585
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA 541
I + +D+G ++ +A N G+ T ++VV A
Sbjct: 12586 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 12619
Score = 30.4 bits (67), Expect = 9.7
Identities = 26/119 (21%), Positives = 50/119 (42%), Gaps = 10/119 (8%)
Query: 749 EYRLERSPVDESG--DEVQYGDVP-VENGMAPFFEMKLKHYK---IFEGMPVTFTCRVAG 802
+Y S ++++G + DV VE MAP FE+ + + + G+ + + G
Sbjct: 14371 KYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKG 14430
Query: 803 NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 861
P P++ W KD + +++ + + L D G + + NP G+ S
Sbjct: 14431 RPAPEVTWTKDNINLKNRAN----IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKS 14485
Score = 30.4 bits (67), Expect = 9.7
Identities = 17/60 (28%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 802 GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 861
G PKP I W KDG + K + + +L + + G YT++ N RI+
Sbjct: 21217 GKPKPSISWLKDGLPL--KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIA 21274
Score = 30.4 bits (67), Expect = 9.7
Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P T ++G P PK+ W + ++ ++D +I D T +L S D G Y
Sbjct: 22290 GSPFTIDVPISGRPAPKVTWKLEEMRLK-ETDRVSITTTKDRT-TLTVKDSMRGDSGRYF 22347
Query: 851 IMAANPQG 858
+ N G
Sbjct: 22348 LTLENTAG 22355
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 270 bits (691), Expect = 4e-72
Identities = 197/724 (27%), Positives = 328/724 (45%), Gaps = 76/724 (10%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP L+N V EG+ V LEC + G P V W+R+ +I+ S DF+I +
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG----- 950
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHF 559
I L+I E F ED+G FTCSA N+ G+ +++ L V + ++ E
Sbjct: 951 ---IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEE 1007
Query: 560 QHFPPPPPILETSSL----ELASKKPSEIQQVNNP------ELGLSRAALQMQFNAAER- 608
+ F ++ T + + +P+ + P E G Q+ N
Sbjct: 1008 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1067
Query: 609 --ETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTAR 666
+ +GV + G ++ + + ++ + ++ + K G ++
Sbjct: 1068 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLE 1127
Query: 667 IASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTY---------EERMARRLLGADS 717
A E + ++ ++ + +E + P Y E+ + R+ + D+
Sbjct: 1128 EADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187
Query: 718 ATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDE----SGDEVQYGDVPVEN 773
V E +QE+ +SS E+RLI EIEYR+ ++ ++E G+E D+
Sbjct: 1188 VVVRTYVE------DQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESE 1241
Query: 774 GMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
+ F+ ++K+Y+I EGM VTF C+++G P PKI W+KDGK+I + Y + DG
Sbjct: 1242 AVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGR 1300
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR----------------S 877
SL +D+G YT A+N +G C+G+L V+ G S
Sbjct: 1301 ASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLS 1360
Query: 878 PRSPSGHPHVRRPRSRS-----------------RDSGDENEPIQERFFRPHFLQAPGDL 920
PRS S P P S R + +E ER ++P F+ P
Sbjct: 1361 PRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSF 1420
Query: 921 TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAG 980
EG+ R D KV G P P+ W DG+ + D HK++++E+G SLII P T D+G
Sbjct: 1421 KCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSG 1480
Query: 981 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQ 1040
+T +A NRAG++S S+ L V A E P+F+EKL+N + +G + ++ R G P P
Sbjct: 1481 EWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPD 1540
Query: 1041 IFWKKENESLT-HSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
I W K ++ + H ++ + + G L I +D+ WYT +A N+AG + ++
Sbjct: 1541 IVWLKNSDIIVPHKYPKIRI-EGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKV 1599
Query: 1100 DVYI 1103
+V +
Sbjct: 1600 NVEV 1603
Score = 119 bits (299), Expect = 1e-26
Identities = 196/916 (21%), Positives = 336/916 (36%), Gaps = 181/916 (19%)
Query: 213 ALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFP--AA 270
A+ S +SP E + + VKSP + + AV H P A
Sbjct: 26162 AVTSPPRVKSP-EPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAP 26220
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P+ Q L+++ E +++ + V W+ +GK+L Q H + L
Sbjct: 26221 PKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELK 26280
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
I E D G Y C + G+ T+ + + S S+ ++ +KT
Sbjct: 26281 INNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKV------SKISETKKSDQKT 26334
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT 450
T ++T + PK +P+S PV LQ+T
Sbjct: 26335 TESTVT-RKTEPKAP------EPISSK-----------------------PVIVTGLQDT 26364
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
V+ V + G P W + G I +++ + K E I +
Sbjct: 26365 TVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLE--------IHK 26416
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPPILE 570
T D+G++TC+ +N GS +S+ +L + + I +
Sbjct: 26417 TDTSDSGLYTCTVKNSAGSVSSSCKLTIKA---------------------------IKD 26449
Query: 571 TSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSN 630
T + +++++K SEI P+ +A +Q + S
Sbjct: 26450 TEAQKVSTQKTSEI----TPQ---KKAVVQEEI-------------------------SQ 26477
Query: 631 KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGT------KDAVIQDL 684
K+L + + +S K ++ KL ++AS ++ EE++ + K V +++
Sbjct: 26478 KALRSEEIKMSEAK------SQEKLALKEEAS---KVLISEEVKKSAATSLEKSIVHEEI 26528
Query: 685 ERKLRFKEDLLNNG-------QPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYK- 736
+ + E++ + Q + +R+ + A + V + E T ++EY+
Sbjct: 26529 TKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRY 26588
Query: 737 -VSSCEQRL-ISEIEYRLER-----SPVDESGDEVQYG-DVPVENGMAPFFEMKLKHYKI 788
VS +Q L I + +R E S E + QY + E AP F + + I
Sbjct: 26589 GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNI 26648
Query: 789 FEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGN 848
EG V FTC ++G P P+I WFK+ IS S + +I R + SL +++ D G
Sbjct: 26649 NEGQNVLFTCEISGEPSPEIEWFKNNLPIS-ISSNVSISRSRN-VYSLEIRNASVSDSGK 26706
Query: 849 YTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR--SRDSGDENEPIQE 906
YTI A N +G+ S T LMV P V P R SGD +
Sbjct: 26707 YTIKAKNFRGQCSATASLMVL---------------PLVEEPSREVVLRTSGDTS----- 26746
Query: 907 RFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGV 966
LQ + + + S + S + K SA M + +
Sbjct: 26747 -------LQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMK-FASMSAQSM----SSM 26794
Query: 967 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYP 1026
+E +S GI + Q S ++ A PP + + +G
Sbjct: 26795 QESFVEMSSSSFMGI------SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKV 26848
Query: 1027 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDN-HGYICLLIQGATKEDAGWYTVS 1085
+ + C G P P++ W + HS ++ H +N L+I K+D G YT+S
Sbjct: 26849 LTVACAFTGEPTPEVTWSCGGRKI-HSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLS 26907
Query: 1086 AKNEAGIVSCTARLDV 1101
NE G S T + +
Sbjct: 26908 LGNEFGSDSATVNIHI 26923
Score = 118 bits (295), Expect = 4e-26
Identities = 195/931 (20%), Positives = 327/931 (35%), Gaps = 162/931 (17%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
QP + H APR ++RS V G V PT V+W+ G EL + I
Sbjct: 25869 QPFTLDH---APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHY 25925
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSR 379
G L TL I + DD+G Y + TN G + A + + G T S+ +
Sbjct: 25926 TNTSGVL-TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVP 25984
Query: 380 AGAMPQAQ----------KKTTSVSLTIGSSSPKTGVT-----------TAVIQPLSVPV 418
P+ KKT+ + + K+ +T +A + S +
Sbjct: 25985 RSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAAL 26044
Query: 419 QQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQG 478
++ R TT A + TK T V EG+ C G P V W R+G
Sbjct: 26045 EEKSLEEKSTTRKIKTTLA--ARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKG 26101
Query: 479 SEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ S ++ K +ST E I+ D G ++ N G + L +
Sbjct: 26102 QVLSTSARHQVTTTKYKSTFE--------ISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26153
Query: 539 TSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQ---QVNNPELGLS 595
A + S PP + S E K P ++ +V +PE
Sbjct: 26154 QKARVTEKAVTS--------------PPRV---KSPEPRVKSPEAVKSPKRVKSPEPSHP 26196
Query: 596 RAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKL 655
+A V P+ K PT V P PP + K
Sbjct: 26197 KA---------------VSPTE------------TKPTPTEKVQHLPVSAPPKITQFLKA 26229
Query: 656 GFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMAR----- 710
K+ ++ + ++ + +D +KL+ + TYE ++
Sbjct: 26230 EASKEIAKLTCVVESSVLRAKEVTWYKD-GKKLKENGHFQFHYSADGTYELKINNLTESD 26288
Query: 711 ------RLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEV 764
+ G + N+Q + + KVS ISE + + ++ + +
Sbjct: 26289 QGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSK-----ISETK-KSDQKTTESTVTRK 26342
Query: 765 QYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHY 824
P P L+ + F + G P+P W KDGK I+ + Y
Sbjct: 26343 TEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT-QGGKY 26401
Query: 825 TIQRDLDG----------------TCSLHTTASTLDDDGNYTIMAAN------------- 855
+ D G TC++ +A ++ TI A
Sbjct: 26402 KLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTS 26461
Query: 856 ---PQGRISCTGRL-----------MVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDEN 901
PQ + + M +A +Q + + + + +S + E
Sbjct: 26462 EITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEK 26521
Query: 902 EPIQERF---------FRPH--FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
+ E R H +++ EG+ + ++G D+ W L+G
Sbjct: 26522 SIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--ATDVKWVLNGVE 26579
Query: 951 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP 1010
+ ++ V + +L I+ + RD GI TCI+ + G +L ++ KE P
Sbjct: 26580 LTNSEEYRYGVSGSD-QTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLS-KELSDAP 26637
Query: 1011 VFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
FI + ++ + +G V C + G P P+I W K N ++ S++ VS+ + + Y L
Sbjct: 26638 AFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN-VSISRSRNVY-SLE 26695
Query: 1071 IQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
I+ A+ D+G YT+ AKN G S TA L V
Sbjct: 26696 IRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726
Score = 113 bits (282), Expect = 1e-24
Identities = 93/361 (25%), Positives = 146/361 (40%), Gaps = 52/361 (14%)
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
EG P F CRV+G K+ W+ K+I P + + T L + +D+G Y
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPS--RFFRMTQFEDTYQLEIAEAYPEDEGTY 3368
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDEN-------- 901
T +A+N G++S T L ++A ++ S + +E
Sbjct: 3369 TFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQL 3428
Query: 902 ------------EPIQERFFR-------PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL 942
P+ F P F++ + + G + + V G+P P +
Sbjct: 3429 SKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKI 3488
Query: 943 SWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA 1002
W +G + P + +K V + HSLII D G YTC+A+N G+ S L +
Sbjct: 3489 QWFFNGVLLTPSADYKF-VFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKIN 3547
Query: 1003 AK-EAHK-------------------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIF 1042
+K E HK PP F+++L+ A G P E V+G P P +
Sbjct: 3548 SKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3607
Query: 1043 WKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVY 1102
W KEN+ L S +H N G ++ +ED+G Y A+N G +C A L V
Sbjct: 3608 WFKENKQLCTSVYYTIIHNPN-GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVL 3666
Query: 1103 I 1103
+
Sbjct: 3667 L 3667
Score = 109 bits (273), Expect = 1e-23
Identities = 141/606 (23%), Positives = 224/606 (36%), Gaps = 135/606 (22%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P P+ +Q+L+ V G ++G P P++ W+ E ++L +T G +
Sbjct: 3190 PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEY 3248
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387
TL++ EAF +D YTC A N G
Sbjct: 3249 TLLLIEAFPEDAAVYTCEAKNDYGV----------------------------------- 3273
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKEL 447
TTS SL SV V +V SP + +PP L
Sbjct: 3274 -ATTSASL-------------------SVEVPEVVSPDQEM--------PVYPPAIITPL 3305
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
Q+T +EGQ +CRV G L+V W+ + +I+ S FR+ Q E+ L
Sbjct: 3306 QDTVTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQF--------EDTYQLE 3356
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPP 567
IAE +PED G +T A N G +STA L + + E+ +E + + + F
Sbjct: 3357 IAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA--PESILHERIEQEIEMEMKEFSSSFL 3414
Query: 568 ILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKA 627
E L A + S+I + EL +F++ + T + I +
Sbjct: 3415 SAEEEGLHSAELQLSKINE--TLELLSESPVYPTKFDSEKEGTGPI--------FIKEVS 3464
Query: 628 NSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERK 687
N++ S+ A L+ +G PK +IQ + V+
Sbjct: 3465 NADISMGDVAT-----------LSVTVIGIPK-----------PKIQWFFNGVLLTPSAD 3502
Query: 688 LRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEE-----TANQEYKVSSCEQ 742
+F D G D + + + E+E A+ +Y + C
Sbjct: 3503 YKFVFD--------------------GDDHSLIILFTKLEDEGEYTCMASNDYGKTICSA 3542
Query: 743 RLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAG 802
L +I + E E+ V + P F +LK + +G+P F V G
Sbjct: 3543 YL--KINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVG 3600
Query: 803 NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISC 862
P P + WFK+ KQ+ S +YTI + +G+ + +D G Y A N G +C
Sbjct: 3601 EPAPTVTWFKENKQLC-TSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTC 3659
Query: 863 TGRLMV 868
L+V
Sbjct: 3660 AAELLV 3665
Score = 109 bits (273), Expect = 1e-23
Identities = 88/322 (27%), Positives = 139/322 (43%), Gaps = 27/322 (8%)
Query: 790 EGMPVTFTCRVAG-NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGN 848
EG V + C++ + ++ W+ +Q+ S+ Y I + DG L+ T DDG
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLE-NSEKYEITYE-DGVAILYVKDITKLDDGT 25141
Query: 849 YTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERF 908
Y N G S L V+ V + + RR + + D ++
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVRE--------VYDYYCRRTMKKIKRRTDTMRLLERP- 25192
Query: 909 FRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN--GV 966
P F + T G+ R ++ P P ++W G+ ++P K E+ G+
Sbjct: 25193 --PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGL 25250
Query: 967 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP-------VFIEKLQNT 1019
+ L I VT+ D YT +A N+ G++S +L V H PP +F L N
Sbjct: 25251 YQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTL---HPPPTDSTLRPMFKRLLANA 25307
Query: 1020 GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 1079
+G V E RV G+PPP + W+K+ + L+ + +H + Y L I+ ED
Sbjct: 25308 ECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH-EGLDYYALHIRDTLPEDT 25366
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G+Y V+A N AG SC A L V
Sbjct: 25367 GYYRVTATNTAGSTSCQAHLQV 25388
Score = 103 bits (258), Expect = 7e-22
Identities = 101/414 (24%), Positives = 174/414 (42%), Gaps = 61/414 (14%)
Query: 154 PKTPHQRKGGPQSQLCDKAANLIEELTSIFKAAKPRNRSPNGESSSPDSGYLSPKNQPSA 213
PKT H G ++ + A +++ S +A+ +S + P + + +P+
Sbjct: 778 PKTEH----GYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRV--RAEPTP 831
Query: 214 LLSASASQSPMEDQGEMEREVKSP---GARHCYQDNQDLAVPHNRKSHPQPHSALHFPAA 270
L + +P + E EVK + V H R++ + + P
Sbjct: 832 LPQFPFADTPDTYKSEAGVEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVE 891
Query: 271 -----PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGD 325
P + L++ V EG V LEC ++G P+P V W+ E ++ ++ D QI + G
Sbjct: 892 IPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG- 950
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ 385
+ L+I EAF +D+GR+TC A N +G+ +TS + ++ +
Sbjct: 951 IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ-------------------VSEE 991
Query: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF--PPVF 443
+K+TT+V+ + + + V+ + S T P YF PV
Sbjct: 992 FEKETTAVTEKFTTEEKRFVESRDVVMTDT-------SLTEEQAGPGEPAAPYFITKPVV 1044
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
K + EG VV C+V G P V W + G + +++ K T E
Sbjct: 1045 QK------LVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNK--QTGE---- 1092
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNND 557
C LVI+ TF +DAG +T RN +G +++A L+ E YE + +S +
Sbjct: 1093 CKLVISMTFADDAGEYTIVVRNKHGETSASASLL------EEADYELLMKSQQE 1140
Score = 101 bits (252), Expect = 3e-21
Identities = 65/191 (34%), Positives = 102/191 (53%), Gaps = 7/191 (3%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR-ENGVHSL 969
P F Q + V EG + +SG P P++SW DG+ + + + + +G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
I VT ++G Y+ ATN +GQ + + EL+V A+ A PP F+++LQ+ V G VRL
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA--PPNFVQRLQSMTVRQGSQVRL 123
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTD-RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
+ RV G+P P + + ++ + S D ++S D + LLI A ED+G Y+V+A N
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYS---LLIAEAYPEDSGTYSVNATN 180
Query: 1089 EAGIVSCTARL 1099
G + TA L
Sbjct: 181 SVGRATSTAEL 191
Score = 95.9 bits (237), Expect = 2e-19
Identities = 95/393 (24%), Positives = 151/393 (38%), Gaps = 92/393 (23%)
Query: 759 ESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQIS 818
E DE Q +E P F +K +K EG F +V G P P+ +WF DG+QI
Sbjct: 1398 EETDESQ-----LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV 1452
Query: 819 PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
H + ++ DGT SL +T D G +T++A N GR S + L V+AV
Sbjct: 1453 NDYTHKVVIKE-DGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV------- 1504
Query: 879 RSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP 938
E +P F++ ++ ++EG M + +G P
Sbjct: 1505 ---------------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1537
Query: 939 TPDLSWQLDGKPVRPDSAHKMLVR-ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSL 997
PD+ W + + P K+ + G +L I+ S+D+ YT A N+AG+++
Sbjct: 1538 NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597
Query: 998 ELVVAA-----------------------------------------------KEAHKPP 1010
++ V KE + P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657
Query: 1011 VFIEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
F +KL + + P ECR+ +G P + W + + L + +R+ M + GY
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPL-EAANRLRMINE-FGYCS 1715
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
L A D+G T A N+ G +A L V
Sbjct: 1716 LDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1748
Score = 93.2 bits (230), Expect = 1e-18
Identities = 68/261 (26%), Positives = 116/261 (44%), Gaps = 43/261 (16%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F L+ + EG TF ++G P P++ WF+DG+ IS + DG
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
L A T + G Y++ A N G+ + T L+V+A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA------------------------- 99
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
E P P+F+Q +TV++G R+ +V+G+PTP + + DG ++ S
Sbjct: 100 ----ETAP-------PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQ-SS 147
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---AHKPPVF 1012
+ +E ++SL+I D+G Y+ ATN G+ + + EL+V +E A K
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 1013 IEKLQNTGVADGYPVRLECRV 1033
+ Q +++ R+E ++
Sbjct: 208 VSTAQ---ISESRQTRIEKKI 225
Score = 89.0 bits (219), Expect = 2e-17
Identities = 44/95 (46%), Positives = 69/95 (72%), Gaps = 1/95 (1%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A P F+Q+L+S V +GS+V L+ RVTG PTP V+++ +G E+ ++ D QI E GDL++
Sbjct: 102 APPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQE-GDLYS 160
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
L+IAEA+ +D+G Y+ ATN G T++AE+ ++G
Sbjct: 161 LLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQG 195
Score = 88.6 bits (218), Expect = 3e-17
Identities = 77/323 (23%), Positives = 128/323 (39%), Gaps = 63/323 (19%)
Query: 246 NQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWF 305
N+ L + +P + P FI+++ + +++ G L V G P P+++WF
Sbjct: 3432 NETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWF 3491
Query: 306 CEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI--EG 363
G L + D + +G D H+LII +D G YTC+A+N G SA + I +G
Sbjct: 3492 FNGVLLTPSADYKFVFDGDD-HSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG 3550
Query: 364 ASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHS 423
D+++ES KS ++ L P
Sbjct: 3551 EGHKDTETESAVAKS--------------------------------LEKLGGP------ 3572
Query: 424 PTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQD 483
C P F KEL+ A+G + E V G P V WF++ ++
Sbjct: 3573 -----CPPH----------FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCT 3617
Query: 484 SPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT 543
S + I+ P T ++ + ED+G++ C A N G +T A+L+V +T
Sbjct: 3618 SVYYTIIH-------NPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDT 3670
Query: 544 ENCSYESMGESNNDHFQHFPPPP 566
+ +S + + FP P
Sbjct: 3671 DMTDTPCKAKSTPEAPEDFPQTP 3693
Score = 88.6 bits (218), Expect = 3e-17
Identities = 63/227 (27%), Positives = 93/227 (40%), Gaps = 33/227 (14%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISP--KSDHYTIQRDLDGTC 834
P F + L + + G V F + +P+P + W+K G++I P YT + D G
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESD-KGLY 25251
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 894
L + T DDD YT++A N G SC +L V HP
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTL-------------HP--------- 25289
Query: 895 RDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
P + RP F + + QEG+ + +VSG+P P L W+ DG+P+
Sbjct: 25290 --------PPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLG 25341
Query: 955 SAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+++ ++L I D G Y ATN AG S L V
Sbjct: 25342 PNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 88.2 bits (217), Expect = 4e-17
Identities = 62/235 (26%), Positives = 106/235 (45%), Gaps = 18/235 (7%)
Query: 772 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLD 831
+ G P F ++ + I G T + V G PKPKI WF +G ++P +D+ + D
Sbjct: 3452 KEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFV---FD 3508
Query: 832 GTC-SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRP 890
G SL + L+D+G YT MA+N G+ C+ L + N +G GH
Sbjct: 3509 GDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI---NSKGE------GHKDTETE 3559
Query: 891 RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
+ ++ P PHFL+ + +G + V G P P ++W + K
Sbjct: 3560 SAVAKSLEKLGGPCP-----PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQ 3614
Query: 951 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
+ + ++ NG + I+ D+G+Y C A N G+++ + EL+V ++
Sbjct: 3615 LCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLED 3669
Score = 87.8 bits (216), Expect = 5e-17
Identities = 91/327 (27%), Positives = 140/327 (42%), Gaps = 58/327 (17%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
F +K K+ E F C V+ P + W KD +++ +D IQ++ L
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQI-TDRIKIQKE-KYVHRLLI 3070
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
++ + D G YT++A G +S T +L V+ + R RS +
Sbjct: 3071 PSTRMSDAGKYTVVAG---GNVS-TAKLFVEGRDVRIRSIKK------------------ 3108
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV--RPDSA 956
E + I+++ +A + V E + D W DG + +
Sbjct: 3109 -EVQVIEKQ-------RAVVEFEVNEDDV-------------DAHWYKDGIEINFQVQER 3147
Query: 957 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
HK +V E +H + I DAG YT +A G+N S+ L V A E PP +++L
Sbjct: 3148 HKYVV-ERRIHRMFISETRQSDAGEYTFVA----GRNRSSVTLYVNAPE---PPQVLQEL 3199
Query: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 1076
Q V G P R + G P P+I W KE + L+ +H D Y LLI+ A
Sbjct: 3200 QPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLH-DGQEYTLLLIE-AFP 3257
Query: 1077 EDAGWYTVSAKNEAGIVSCTARLDVYI 1103
EDA YT AKN+ G+ + +A L V +
Sbjct: 3258 EDAAVYTCEAKNDYGVATTSASLSVEV 3284
Score = 87.4 bits (215), Expect = 7e-17
Identities = 70/300 (23%), Positives = 129/300 (43%), Gaps = 39/300 (13%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP FI + RSQ + EG V C ++G P+P + WF + + ++ I ++++L
Sbjct: 26636 APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSI-SRSRNVYSL 26694
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI---------EGASSTDSD-SESLAFKSR 379
I A D+G+YT A N G + +A + + E T D S +F S+
Sbjct: 26695 EIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQ 26754
Query: 380 AGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVP-------------------VQQ 420
+ M ++++ + S + S+S T + A + S+ + Q
Sbjct: 26755 SVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQ 26814
Query: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
+ S TS + + PP + ++ EG+V+ + C G P +V W G +
Sbjct: 26815 LESSTSKMLK---AGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRK 26871
Query: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
I R +++ TL+I + +D G++T S N++GS ++T + + S
Sbjct: 26872 IHSQEQGRF------HIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 26925
Score = 83.6 bits (205), Expect = 1e-15
Identities = 62/199 (31%), Positives = 88/199 (44%), Gaps = 12/199 (6%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P LQ +TVQ GK R +SG P P +SW + + + K L + ++L+
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFL-HDGQEYTLL 3251
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP--------PVFIEKLQNTGVA 1022
+ DA +YTC A N G + S L V E P P I LQ+T +
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
+G P R +CRV G ++ K+ + R++ +D + L I A ED G Y
Sbjct: 3312 EGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQ---LEIAEAYPEDEGTY 3368
Query: 1083 TVSAKNEAGIVSCTARLDV 1101
T A N G VS TA L +
Sbjct: 3369 TFVASNAVGQVSSTANLSL 3387
Score = 83.6 bits (205), Expect = 1e-15
Identities = 65/204 (31%), Positives = 94/204 (46%), Gaps = 26/204 (12%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA-HKMLVRENGVHSL 969
PHF + +L V+ + CKV+G P P + W GK + D +++ + G H L
Sbjct: 24431 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24490
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNS--FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
II VT DA +Y ATN+ G S SLE+ V AK H P +E + G V
Sbjct: 24491 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK-IHLPKT-LEGMGAVHALRGEVV 24548
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLI----------QGATKE 1077
++ G P P I W+K + + DN+G+ +++ G ++
Sbjct: 24549 SIKIPFSGKPDPVITWQKGQDLI-----------DNNGHYQVIVTRSFTSLVFPNGVERK 24597
Query: 1078 DAGWYTVSAKNEAGIVSCTARLDV 1101
DAG+Y V AKN GI T LDV
Sbjct: 24598 DAGFYVVCAKNRFGIDQKTVELDV 24621
Score = 82.4 bits (202), Expect = 2e-15
Identities = 187/867 (21%), Positives = 319/867 (36%), Gaps = 161/867 (18%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVT--GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
P F +KL S + + ECR+T G+PT V W +GK L +++ E G +
Sbjct: 1657 PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC-S 1715
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQK 388
L A+ D+G TC ATN G+D TSA + ++ D +SL +S+ +P+ +K
Sbjct: 1716 LDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK-------DEKSLVEESQ---LPEGRK 1765
Query: 389 KTTSVS--LTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKE 446
+ + TGVTT + +PD Y PV
Sbjct: 1766 GLQRIEELERMAHEGALTGVTTDQKEKQ---------------KPD--IVLYPEPV---- 1804
Query: 447 LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTL 506
V EG+ CRV G P +V W+ G I+ S FR+ + I L
Sbjct: 1805 ----RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV---------RYDGIHYL 1851
Query: 507 VIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPP 566
I + D G +A N G +L + E + P P
Sbjct: 1852 DIVDCKSYDTGEVKVTAENPEGVIEHKVKLEI-----------QQREDFRSVLRRAPEPR 1900
Query: 567 PILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHP--SRGVNGLIN 624
P K E+Q+V+ P + + ++ AER T+ P S +
Sbjct: 1901 PEFHVHE---PGKLQFEVQKVDRP-VDTTETKEVVKLKRAERITHEKVPEESEELRSKFK 1956
Query: 625 GKANSNKSLPTPAVLLSPTKEP---PPLLAKPK---LGFPKKASRTARIASDEEIQGTKD 678
+ AV L K+ LL K K L + K+ + + A EE + T
Sbjct: 1957 RRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIP 2016
Query: 679 AVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQ-----EPEEETANQ 733
D K+ + P++ ER+ + +G S F ++ +PE E
Sbjct: 2017 TFKPD---KIELSPSM---EAPKIF--ERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKN 2068
Query: 734 EYKVSSCE-------QRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHY 786
K+ + + + E+ R + + D + V+ ++ E F ++ K
Sbjct: 2069 GVKIERSDRIYWYWPEDNVCELVIR-DVTAEDSASIMVKAINIAGETSSHAFLLVQAKQL 2127
Query: 787 KIF-----------EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
F + TF C + P K+ W+KDG ++ + D Y + D
Sbjct: 2128 ITFTQELQDVVAKEKDTMATFECETS-EPFVKVKWYKDGMEVH-EGDKYRMHSDRKVHFL 2185
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
T T D + ++ + + T +L+V+
Sbjct: 2186 SILTIDTSDAEDYSCVLVEDE--NVKTTAKLIVEGA------------------------ 2219
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
F++ D+ V E ++C VS + W + ++ +
Sbjct: 2220 --------------VVEFVKELQDIEVPESYSGELECIVSP-ENIEGKWYHNDVELKSNG 2264
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK 1015
+ + R G +L ++ VT D G Y+ + + + K +P ++
Sbjct: 2265 KYTITSR-RGRQNLTVKDVTKEDQGEYSFVIDGK--------KTTCKLKMKPRPIAILQG 2315
Query: 1016 LQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGAT 1075
L + V +G V+LE +V + + W K+ + + S DRV + D ++ LLI+ T
Sbjct: 2316 LSDQKVCEGDIVQLEVKV-SLESVEGVWMKDGQEVQPS-DRVHIVIDKQSHM-LLIEDMT 2372
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDVY 1102
KEDAG Y+ + A +S + R+ VY
Sbjct: 2373 KEDAGNYSFTI--PALGLSTSGRVSVY 2397
Score = 81.6 bits (200), Expect = 4e-15
Identities = 71/279 (25%), Positives = 119/279 (42%), Gaps = 37/279 (13%)
Query: 264 ALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL--HNTPDIQIHC 321
A+ P F++KL++ + EGSR+ ++ R TGNP P + W + H P I+I
Sbjct: 1503 AVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1562
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
G+ L I D+ YT A N +G DTT +V +E + F
Sbjct: 1563 TKGEA-ALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-----------VEF----- 1605
Query: 382 AMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP 441
A P+ ++K + + G+ K + ++PL + Q L + P
Sbjct: 1606 AEPEPERK---LIIPRGTYRAKE-IAAPELEPLHLRYGQEQWEEGDLYDKEKQQ----KP 1657
Query: 442 VFTKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
F K+L + + ECR+ G P + V+W G ++ + R++ +
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINE------- 1710
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
C+L + D+GI TC A N YG+ ++A L+V
Sbjct: 1711 -FGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1748
Score = 79.0 bits (193), Expect = 2e-14
Identities = 63/240 (26%), Positives = 100/240 (41%), Gaps = 10/240 (4%)
Query: 772 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVA--GNPKPKIYWFKDGKQISPKSDHYTIQRD 829
E PFF+ KL ++ P F CR+ G+P + W DGK + + I
Sbjct: 1652 EKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEF 1711
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889
G CSL + D G T A N G + L+V+ + P G ++R
Sbjct: 1712 --GYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQR 1769
Query: 890 PRSRSRDSGDEN----EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQ 945
R + + Q+ +P + P + V EG+ R C+V+G P P ++W
Sbjct: 1770 IEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWY 1829
Query: 946 LDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
L+G+ +R + + VR +G+H L I S D G A N G ++L + +E
Sbjct: 1830 LNGQLIR--KSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRE 1887
Score = 79.0 bits (193), Expect = 2e-14
Identities = 160/774 (20%), Positives = 269/774 (34%), Gaps = 182/774 (23%)
Query: 444 TKELQNTAVAEGQVVVLECRVR--GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
TK ++N V E + EC V P + W + G EI+ S F+I+ +
Sbjct: 2839 TKTMKNIEVPETKTASFECEVSHFNVPSM---WLKNGVEIEMSEKFKIVVQG-------- 2887
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLV--------VTSANTENCSYESMGE 553
++ L+I T ED+ +T ND SAT T + + + + ++E
Sbjct: 2888 KLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVN 2947
Query: 554 SNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGV 613
++ I T ++ +KK + + N G +AA+
Sbjct: 2948 YEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFG----------DAADYT---- 2993
Query: 614 HPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPL--LAKPKLGFPKKASR----TARI 667
+ GKA S +L A + K + L K + F + S +
Sbjct: 2994 --------FVAGKATSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWM 3045
Query: 668 ASDEEIQGTKDAVIQD---LERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVF--- 721
D+E+Q T IQ + R L + + G+ + ++ L + V
Sbjct: 3046 KDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRS 3105
Query: 722 ---NIQEPEEETANQEYKVSS-----------------CEQRLISEIEYRLERSPVDES- 760
+Q E++ A E++V+ ++R +E R+ R + E+
Sbjct: 3106 IKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETR 3165
Query: 761 -GDEVQYGDVPVENGMA----------PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIY 809
D +Y V N + P +L+ + G P F ++G P+PKI
Sbjct: 3166 QSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKIS 3225
Query: 810 WFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ 869
W+K+ + +S + + T L + +D YT A N G + + L V+
Sbjct: 3226 WYKEEQLLSTGFKCKFLHDGQEYTLLL--IEAFPEDAAVYTCEAKNDYGVATTSASLSVE 3283
Query: 870 AVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCR 929
P V P D+ P+ + P + D EG+ R
Sbjct: 3284 V--------------PEVVSP--------DQEMPV----YPPAIITPLQDTVTSEGQPAR 3317
Query: 930 MDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR 989
C+VSG +SW K ++P +M E+ + L I D G YT +A+N
Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED-TYQLEIAEAYPEDEGTYTFVASNA 3375
Query: 990 AGQNSFSLELVVAAKEA-----------------------------HKPPVFIEKLQNT- 1019
GQ S + L + A E+ H + + K+ T
Sbjct: 3376 VGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETL 3435
Query: 1020 ---GVADGYPVRLECR----------------------------VLGVPPPQIFWKKENE 1048
+ YP + + V+G+P P+I W
Sbjct: 3436 ELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGV 3495
Query: 1049 SLTHSTD-RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
LT S D + D+H I L + ED G YT A N+ G C+A L +
Sbjct: 3496 LLTPSADYKFVFDGDDHSLIILFTK---LEDEGEYTCMASNDYGKTICSAYLKI 3546
Score = 79.0 bits (193), Expect = 2e-14
Identities = 68/272 (25%), Positives = 110/272 (40%), Gaps = 50/272 (18%)
Query: 742 QRLISEIEYRLERSPVDESGDEVQYG----------DVPVENGMAPFFEMKLKHYKIFEG 791
+ LI +EY R + G E ++ DVP++ AP F+ +L++ +
Sbjct: 24390 KNLIEGLEYEF-RVKCENLGGESEWSEISEPITPKSDVPIQ---APHFKEELRNLNVRYQ 24445
Query: 792 MPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTI 851
T C+V G+PKP + W++ GK+I Y IQ G L + T DD Y +
Sbjct: 24446 SNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQV 24505
Query: 852 MAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRP 911
A N G +S T L V+ + + P
Sbjct: 24506 RATNQGGSVSGTASLEVE----------------------------------VPAKIHLP 24531
Query: 912 HFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLII 971
L+ G + G++ + SG P P ++WQ G+ + ++ H ++ SL+
Sbjct: 24532 KTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ-KGQDLIDNNGHYQVIVTRSFTSLVF 24590
Query: 972 -EPVTSRDAGIYTCIATNRAGQNSFSLELVVA 1002
V +DAG Y A NR G + ++EL VA
Sbjct: 24591 PNGVERKDAGFYVVCAKNRFGIDQKTVELDVA 24622
Score = 77.8 bits (190), Expect = 5e-14
Identities = 42/99 (42%), Positives = 63/99 (63%), Gaps = 8/99 (8%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP F + LQ+ V +G V L+ RV G P V+++R G+EIQ S DF+I Q+
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQE------- 155
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ +L+IAE +PED+G ++ +A N G ATSTA+L+V
Sbjct: 156 -GDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 77.4 bits (189), Expect = 7e-14
Identities = 145/666 (21%), Positives = 234/666 (35%), Gaps = 132/666 (19%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
PV ++++ VA G + C ++ AP ++ QWF+ G EI +S I K
Sbjct: 4337 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSK------- 4389
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQ 560
I +L I T D G +TC A N+YGS + TA L VT E + + E
Sbjct: 4390 -YISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERK----- 4443
Query: 561 HFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVN 620
P P E + K+P E E V P +
Sbjct: 4444 ----PEPKEEVVLKSVLRKRP-------------------------EEEEPKVEPKK--- 4471
Query: 621 GLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAV 680
+ + PAV EPPP ++ P R +I ++ K A+
Sbjct: 4472 ---------LEKVKKPAV-----PEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAI 4517
Query: 681 -IQDLERKLRFKEDLLNNGQPRLTYEER-MARRLLGADSATVFNIQEPEEETANQEYKVS 738
+ E K + + ++ P + E +A + + P+EE A + +
Sbjct: 4518 PLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIK 4577
Query: 739 SCEQRLISEIEYRLER--------SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKI-- 788
++ S IE + P DE+ Q VP++ F ++K +
Sbjct: 4578 GVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLK------FVKEIKDIILTE 4631
Query: 789 --FEGMPVTFTCRVAGNPKPKI-YWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 845
F G F C V +P I W KDG I H I D LH L D
Sbjct: 4632 SEFVGSSAIFECLV--SPSTAITTWMKDGSNIRESPKHRFIADGKDR--KLHIIDVQLSD 4687
Query: 846 DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQ 905
G YT + + T +L+V E +
Sbjct: 4688 AGEYTCVLRLGNKEKTSTAKLVV---------------------------------EELP 4714
Query: 906 ERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENG 965
RF + ++TV +G+ + C+++ D+ W+ DGK V +
Sbjct: 4715 VRFVK----TLEEEVTVVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGL 4768
Query: 966 VHSLIIEPVTSRDAGIYTCIATNRAG-QNSFSLELVVAAKEAHKPPVFIEKLQNTGVADG 1024
+ +L I DAG YT N + S +++V ++ P+ + ++ G A
Sbjct: 4769 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTA-- 4826
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD-NHGYICLLIQGATKEDAGWYT 1083
C + P ++K +E D+ + +D NH Y L I+ A ED Y
Sbjct: 4827 ---IFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLY--LKIKNAMPEDIAEYA 4881
Query: 1084 VSAKNE 1089
V + +
Sbjct: 4882 VEIEGK 4887
Score = 76.6 bits (187), Expect = 1e-13
Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 12/195 (6%)
Query: 915 QAPG------DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS 968
+APG D+T + G+ ++ C++ G P PD+ W GK + +KM + H+
Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMS-SDGRTHT 24092
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
L + D G+YTCIATN G+ S +L++ A P +++ V G +R
Sbjct: 24093 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAV--GSTLR 24150
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L +G P P + W + L +++ +++ H ++ K AG Y V N
Sbjct: 24151 LHVMYIGRPVPAMTW-FHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSN 24209
Query: 1089 EAGIVSCTARLDVYI 1103
G V A LDV I
Sbjct: 24210 VFGTVD--AILDVEI 24222
Score = 75.1 bits (183), Expect = 3e-13
Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 42/238 (17%)
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
P++ P + ++TV EG+ ++C +SG P+P ++W + + S +
Sbjct: 889 PVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIE-SSIDFQITF 947
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-------------- 1008
++G+ L+I + D+G +TC A N AG S S L V E +
Sbjct: 948 QSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEE 1007
Query: 1009 ---------------------------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQI 1041
P FI K + +G V C+V G P P +
Sbjct: 1008 KRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHV 1067
Query: 1042 FWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
+WKK LT + G L+I +DAG YT+ +N+ G S +A L
Sbjct: 1068 YWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 75.1 bits (183), Expect = 3e-13
Identities = 72/292 (24%), Positives = 121/292 (41%), Gaps = 49/292 (16%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F + ++ +V E R EC V+ P V+W + +EL T I+I E +H L+I
Sbjct: 3014 FRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKY-VHRLLIP 3071
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTS 392
D G+YT +A G + ++A++F+EG + +S + +K+
Sbjct: 3072 STRMSDAGKYTVVA----GGNVSTAKLFVEG--------RDVRIRSIKKEVQVIEKQRAV 3119
Query: 393 VSLTIGSSSPKTGVTTAVIQPLSVPVQQVH----------------------SPTSYLCR 430
V + I+ ++ VQ+ H T R
Sbjct: 3120 VEFEVNEDDVDAHWYKDGIE-INFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR 3178
Query: 431 PDGTTTAYF----PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
+ T Y PP +ELQ V G+ + G P ++ W+++ +
Sbjct: 3179 NRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFK 3238
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ L + +E TL++ E FPEDA ++TC A+NDYG AT++A L V
Sbjct: 3239 CKFLH-------DGQEY-TLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV 3282
Score = 74.3 bits (181), Expect = 6e-13
Identities = 78/323 (24%), Positives = 123/323 (38%), Gaps = 66/323 (20%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHN--TPDIQIHCEGGD 325
PAAP FI K Q++ EG V C+V GNP P V W G L + + + G+
Sbjct: 1033 PAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGE 1092
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ 385
L+I+ F DD G YT + N G + SA + E +D E L KS+ + Q
Sbjct: 1093 C-KLVISMTFADDAGEYTIVVRNKHGETSASASLLEE------ADYE-LLMKSQQEMLYQ 1144
Query: 386 AQKKTTSVSLTIGSSSP--------------------KTGVTTAVIQPL----------- 414
Q +G ++P K T V++
Sbjct: 1145 TQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSF 1204
Query: 415 ------SVPVQQVHSPTSYLCRPDG--------TTTAYFPPVFTKELQNTAVAEGQVVVL 460
+ + + + L DG + + F ++N + EG V
Sbjct: 1205 EERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTF 1264
Query: 461 ECRVRGAPPLQVQWFRQGSEIQDSPDFRI--LQKKPRSTAEPEEICTLVIAETFPEDAGI 518
C++ G P ++ W++ G I+ +++ LQ + +L I PED GI
Sbjct: 1265 HCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQ---------DGRASLRIPVVLPEDEGI 1315
Query: 519 FTCSARNDYGSATSTAQLVVTSA 541
+T A N G+A + +L V A
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPA 1338
Score = 73.9 bits (180), Expect = 8e-13
Identities = 60/269 (22%), Positives = 118/269 (43%), Gaps = 17/269 (6%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F ++++ + EG V C+++G P P++ W+ +GK + + Q+ +L I
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDS--ESLAFKSRAGAMPQAQKKT 390
+D G YT A+N G+ S ++++E A+ + + +L SR ++
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPD-GTTTAYFPPVFTKELQN 449
+ + ++ SP ++ A + P + SP L D + PVF + +
Sbjct: 1367 SPIRMSPARMSP-ARMSPARMSPARM------SPGRRLEETDESQLERLYKPVFVLKPVS 1419
Query: 450 TAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIA 509
EGQ + +V G P + WF G +I + +++ K+ + +L+I
Sbjct: 1420 FKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-------SLIIV 1472
Query: 510 ETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P D+G +T A+N G ++ + L V
Sbjct: 1473 PATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 72.4 bits (176), Expect = 2e-12
Identities = 53/186 (28%), Positives = 86/186 (46%), Gaps = 9/186 (4%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
D +EG + + ++ +++W + K V D K L +N ++L+I+ V + D
Sbjct: 4251 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTED 4307
Query: 979 -AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVP 1037
G Y C A N +G+ + S +L V + A PV K++ VA G+ + C + P
Sbjct: 4308 HQGEYVCEALNDSGKTATSAKLTVVKRAA---PVIKRKIEPLEVALGHLAKFTCEIQSAP 4364
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 1097
+ W K + + +D+ S+ + L I D G YT A NE G VSCTA
Sbjct: 4365 NVRFQWFKAGREI-YESDKCSIRSSKY-ISSLEILRTQVVDCGEYTCKASNEYGSVSCTA 4422
Query: 1098 RLDVYI 1103
L V +
Sbjct: 4423 TLTVTV 4428
Score = 69.7 bits (169), Expect = 1e-11
Identities = 147/793 (18%), Positives = 273/793 (34%), Gaps = 80/793 (10%)
Query: 215 LSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFI 274
+ AS+S ++ Q RE S + + A+ + A R +
Sbjct: 26008 MEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARIL 26067
Query: 275 QKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEA 334
K RS V EG C G P P V W +G+ L + Q+ T I+
Sbjct: 26068 TKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYK-STFEISSV 26126
Query: 335 FEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVS 394
D G Y+ + N G + I+ A T+ S P+ + V
Sbjct: 26127 QASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTS---------PPRVKSPEPRVK 26177
Query: 395 LTIGSSSPKTGVTTAVIQPLSV-PVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVA 453
SPK + P +V P + +PT + PP T+ L+ A A
Sbjct: 26178 SPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH----LPVSAPPKITQFLK--AEA 26231
Query: 454 EGQVVVLECRVRGA--PPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
++ L C V + +V W++ G +++++ F+ T E L I
Sbjct: 26232 SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQ-FHYSADGTYE------LKINNL 26284
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGES-NNDHFQHFPPPPPILE 570
D G + C + G++ + Q + + + + + E+ +D E
Sbjct: 26285 TESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTE 26344
Query: 571 TSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSN 630
+ E S KP + + + + A E + G GK +
Sbjct: 26345 PKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS 26404
Query: 631 KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRF 690
+ + + T L + K ++ + + I+ KD Q K+
Sbjct: 26405 EDKGGFFLEIHKTDTSDSGLYTCTV---KNSAGSVSSSCKLTIKAIKDTEAQ----KVST 26457
Query: 691 KEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEY 750
++ Q + +E ++++ L ++ + + E+ +E + +
Sbjct: 26458 QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAAT 26517
Query: 751 RLERSPVDESGDEVQYGDVPVENGMAPFFEMKL--KHYKIFEGMPVTFTCRVAGNPKPKI 808
LE+S V E + V E+K I EG + +AG K
Sbjct: 26518 SLEKSIVHEEITKTSQASEEVRT----HAEIKAFSTQMSINEGQRLVLKANIAGATDVK- 26572
Query: 809 YWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
W +G +++ ++ D T ++ + D+G T ++ +G + C L +
Sbjct: 26573 -WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHR--DEGILTCISKTKEGIVKCQYDLTL 26629
Query: 869 QAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLC 928
S + +PRS++ + EG+
Sbjct: 26630 --------SKELSDAPAFISQPRSQN---------------------------INEGQNV 26654
Query: 929 RMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATN 988
C++SG P+P++ W + P+ S++ + R V+SL I + D+G YT A N
Sbjct: 26655 LFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKN 26713
Query: 989 RAGQNSFSLELVV 1001
GQ S + L+V
Sbjct: 26714 FRGQCSATASLMV 26726
Score = 69.3 bits (168), Expect = 2e-11
Identities = 120/637 (18%), Positives = 230/637 (36%), Gaps = 71/637 (11%)
Query: 255 RKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT 314
RK+ P+ + + P + L+ V+ S + TG P P W +GK +
Sbjct: 26341 RKTEPKAPEPIS--SKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQG 26398
Query: 315 PDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL 374
++ + G L I + D+G YTC N +GS ++S ++ I+ T++ S
Sbjct: 26399 GKYKLSEDKGGFF-LEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQKVST 26457
Query: 375 AFKSRAGAMPQA-------QK--KTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT 425
S +A QK ++ + ++ S K + + L + + T
Sbjct: 26458 QKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAAT 26517
Query: 426 SY---LCRPDGTTTAYFPPVFTKELQNTA------VAEGQVVVLECRVRGAPPLQVQWFR 476
S + + T T+ + A + EGQ +VL+ + GA V+W
Sbjct: 26518 SLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT--DVKWVL 26575
Query: 477 QGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL 536
G E+ +S ++R + ++ TL I + D GI TC ++ G L
Sbjct: 26576 NGVELTNSEEYRY------GVSGSDQ--TLTIKQASHRDEGILTCISKTKEGIVKCQYDL 26627
Query: 537 VVTSANTENCSYESMGESNN-DHFQHFPPPPPILETSSLELA-SKKPSEIQQVNNPELGL 594
++ ++ ++ S S N + Q+ I S E+ K I +N +
Sbjct: 26628 TLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISR 26687
Query: 595 SRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPK 654
SR ++ A +G + + N G+ ++ SL ++ P++E
Sbjct: 26688 SRNVYSLEIRNASVSDSGKYTIKAKN--FRGQCSATASLMVLPLVEEPSREV-------- 26737
Query: 655 LGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLG 714
R + D +QG+ + + K++ + + +
Sbjct: 26738 ---------VLRTSGDTSLQGSFSSQSVQMSAS---KQEASFSSFSSSSASSMTEMKFAS 26785
Query: 715 ADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENG 774
+ ++ ++QE E ++ + S +L S L+ G
Sbjct: 26786 MSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGI----------------RG 26829
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
+ P E I EG +T C G P P++ W G++I + + D
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLT 26889
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAV 871
+L D G YT+ N G S T + ++++
Sbjct: 26890 TLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 26926
Score = 65.5 bits (158), Expect = 3e-10
Identities = 38/105 (36%), Positives = 55/105 (52%), Gaps = 3/105 (2%)
Query: 258 HPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDI 317
HP P + P F + L + E EG V E RV+G P P ++W +G+ L P+I
Sbjct: 25288 HPPPTDST---LRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNI 25344
Query: 318 QIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+I EG D + L I + +DTG Y ATN +GS + A + +E
Sbjct: 25345 EIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389
Score = 64.7 bits (156), Expect = 5e-10
Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Query: 1009 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
PP + L+N V +G V LEC + G P P + W +E+ + S D Q G
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQS--GIAR 953
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 1104
L+I+ A ED+G +T SA NEAG VS + L V +S
Sbjct: 954 LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 989
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/127 (31%), Positives = 66/127 (51%), Gaps = 4/127 (3%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT--PDIQIHCEGGDLH 327
AP F Q L+S V EGS E ++G P P V WF +G+ + + P +QI G
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA- 63
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL-AFKSRAGAMPQA 386
L I + ++GRY+ ATN SG T++AE+ ++ ++ + + L + R G+ +
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 387 QKKTTSV 393
Q + T +
Sbjct: 124 QVRVTGI 130
Score = 62.4 bits (150), Expect = 2e-09
Identities = 198/944 (20%), Positives = 315/944 (33%), Gaps = 199/944 (21%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F L+ V E + EC +T V W +G ++ + D G H L+I
Sbjct: 4991 FAVPLKDVTVPERRQARFECVLTREAN--VIW-SKGPDIIKSSDKFDIIADGKKHILVIN 5047
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGA---------SSTDSDSESLAF------- 376
++ DD G YT TSA +F+ G T + E+ F
Sbjct: 5048 DSQFDDEGVYTAEVEGKK----TSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHE 5103
Query: 377 KSRAGAMPQAQKKTTSVSLTIGSSSP--KTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT 434
K K TS ++ I S K + + +S Q+ + L
Sbjct: 5104 KMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDIS----QIKAQVKELSSTAQL 5159
Query: 435 TTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKP 494
P FT +L + E + L+C V P V+WF+ G EI SP + I
Sbjct: 5160 KVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSPKYSIKADGL 5217
Query: 495 RSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT----------E 544
R L I + +D G + C D A T + + E
Sbjct: 5218 RR--------ILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGE 5269
Query: 545 NCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFN 604
+E + H Q P+ + E+ I ++N +LG++ ++ F
Sbjct: 5270 TAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTG---EVSFQ 5326
Query: 605 AAERETNGVHPSRGVNGLINGKANSN-KSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASR 663
AA N K+ +N K P + ++P + + K + F + SR
Sbjct: 5327 AA-----------------NAKSAANLKVKELPLIFITPLSD-VKVFEKDEAKFECEVSR 5368
Query: 664 ----------TARIASDEEIQGTKD----------AVIQDLERKLRFKEDLLNNGQ---- 699
T I D+ + KD A +D + + ED +G+
Sbjct: 5369 EPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIE 5428
Query: 700 -PRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVD 758
RL + + + VF ++ + N K +QRL + ++
Sbjct: 5429 GIRLKFLTPLKDVTAKEKESAVFTVELSHD---NIRVKWFKNDQRLHTTRSVSMQDEGKT 5485
Query: 759 ESGDEVQYGDVPVEN---------GMA-----------PFFEMKLKHYKIFEGMPVTFTC 798
S + + D+ +++ GM+ P+F KL+ Y E V C
Sbjct: 5486 HS---ITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQC 5542
Query: 799 RVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDD-GNYTIMAANPQ 857
++ P + WFKDGK+I P + DG + L D G YT
Sbjct: 5543 EISKADAP-VKWFKDGKEIKPSKNAVI---KADGKKRMLILKKALKSDIGQYTCDC---- 5594
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP 917
G +G+L ++ + P R + S D+ + LQ P
Sbjct: 5595 GTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIH-ANWKLKGEALLQTP 5653
Query: 918 GDLTVQEGKL-------CRMD---------------------CKVSGLPTP--------- 940
+EGK+ CR+D +V GL P
Sbjct: 5654 DCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAG 5713
Query: 941 --------------DLSWQLDGKPVRPDSAHKMLVRENG-VHSLIIEPVTSRDAGIYTCI 985
+ W L GK + P + K++ R G VH+L + V DAG
Sbjct: 5714 ETATFDCELSYEDIPVEWYLKGKKLEP--SDKVVPRSEGKVHTLTLRDVKLEDAGEVQLT 5771
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPV-FIEKLQNTGVADGYPVRLECRVLGVPPPQIFWK 1044
A F + KE PPV F + L++ V +G LEC V ++ W
Sbjct: 5772 A------KDFKTHANLFVKE---PPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWF 5821
Query: 1045 KENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
K + S + + D L+I T ED YT AK+
Sbjct: 5822 KNGTEILKS-KKYEIVADGR-VRKLVIHDCTPEDIKTYTCDAKD 5863
Score = 61.6 bits (148), Expect = 4e-09
Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 7/143 (4%)
Query: 770 PVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD 829
P ++ + P F+ L + + EG V F RV+G P P + W KDG+ +S + I
Sbjct: 25291 PTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEG 25350
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHP-HVR 888
LD +LH + +D G Y + A N G SC L V+ + + + +S H HV+
Sbjct: 25351 LD-YYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQ 25409
Query: 889 RP-----RSRSRDSGDENEPIQE 906
+ R SG E+ P+ +
Sbjct: 25410 KQIDKTLRMAEILSGTESVPLTQ 25432
Score = 61.2 bits (147), Expect = 5e-09
Identities = 44/184 (23%), Positives = 76/184 (41%), Gaps = 4/184 (2%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P P F+++L+ A+G E V G P P V WF E K+L + I
Sbjct: 3572 PCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSG 3631
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASSTDSDSESLAFKSRAGAMPQ 385
T I+ + +D+G Y C A N G T +AE V +E TD+ ++ + PQ
Sbjct: 3632 TFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQ 3691
Query: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTK 445
K +V T V +++ + + ++ + + ++ P+ +
Sbjct: 3692 TPLKGPAVEALDSEQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQL--PLGAQ 3749
Query: 446 ELQN 449
ELQ+
Sbjct: 3750 ELQS 3753
Score = 61.2 bits (147), Expect = 5e-09
Identities = 66/266 (24%), Positives = 105/266 (39%), Gaps = 25/266 (9%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+ ++ L S EV E E ++ + W +G+ L TPD +I E G +H+L++
Sbjct: 5611 KLVRPLHSVEVMETETARFETEISEDDI-HANWKLKGEALLQTPDCEIK-EEGKIHSLVL 5668
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG-----------ASSTDSDSESLAFKSRA 380
D TG A N S + + G A T + L+++
Sbjct: 5669 HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP 5728
Query: 381 GAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFP 440
KK + S K V T ++ + + T+ + P
Sbjct: 5729 VEWYLKGKKLEPSDKVVPRSEGK--VHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEP 5786
Query: 441 PV-FTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PV FTK L++ V EG VLEC V +V+WF+ G+EI S + I+
Sbjct: 5787 PVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIV--------A 5837
Query: 500 PEEICTLVIAETFPEDAGIFTCSARN 525
+ LVI + PED +TC A++
Sbjct: 5838 DGRVRKLVIHDCTPEDIKTYTCDAKD 5863
Score = 60.8 bits (146), Expect = 7e-09
Identities = 36/94 (38%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKE-LHNTPDIQIHCEGGDLHT 328
AP F ++LR+ V S L C+VTG+P P V+W+ +GKE + + +I G H
Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
LIIA +DD Y ATN GS + +A + +E
Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523
Score = 58.9 bits (141), Expect = 3e-08
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP ++++ G L C++ G P P ++W+ GKEL + ++ + G HTL
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSD-GRTHTL 24093
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+ ++D G YTC+ATN G TS+++ ++
Sbjct: 24094 TVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24126
Score = 58.2 bits (139), Expect = 4e-08
Identities = 68/279 (24%), Positives = 108/279 (38%), Gaps = 25/279 (8%)
Query: 262 HSALHFPAAP-RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIH 320
H+ L P F + L Q V EG+ LEC V+ +V+WF G E+ + +I
Sbjct: 5778 HANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIV 5836
Query: 321 CEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSA----EVFIEGASSTDSDSESLAF 376
+ G + L+I + +D YTC A + S + F+ + + +A
Sbjct: 5837 AD-GRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMAR 5895
Query: 377 KSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC-----RP 431
+ A+ K I ++ ++ L + + Y C R
Sbjct: 5896 FECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTART 5955
Query: 432 DGTTTAY-FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
G T VFTK L N V+E + L C V P +V W++ EI ++ + IL
Sbjct: 5956 SGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEIL 6014
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTC---SARND 526
+ + LVI EDAG + C S+R D
Sbjct: 6015 TEGRKR--------ILVIQNAHLEDAGNYNCRLPSSRTD 6045
Score = 58.2 bits (139), Expect = 4e-08
Identities = 68/290 (23%), Positives = 101/290 (34%), Gaps = 73/290 (25%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F L ++ G V +T +P P V W+ G+++ + + +
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKY---------- 25242
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
FE D G Y L N + +TD D+E T
Sbjct: 25243 ---TFESDKGLYQ-LTIN---------------SVTTDDDAEY----------------T 25267
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT 450
G S K +T + P PT RP +F + L N
Sbjct: 25268 VVARNKYGEDSCKAKLTVTLHPP----------PTDSTLRP----------MFKRLLANA 25307
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
EGQ V E RV G PP ++W + G + P+ I+ E + L I +
Sbjct: 25308 ECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH-------EGLDYYALHIRD 25360
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQ 560
T PED G + +A N GS + A L V + ++S E + H Q
Sbjct: 25361 TLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSK-EEHERHVQ 25409
Score = 57.4 bits (137), Expect = 7e-08
Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 8/143 (5%)
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG----VAD 1023
S ++E + + A N G++ SL L V ++ PP +L G V
Sbjct: 8856 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKA 8915
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD----NHGYICLLIQGATKEDA 1079
G PV + V G+P P+I W K + TD + + ++ + L I A +ED
Sbjct: 8916 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 8975
Query: 1080 GWYTVSAKNEAGIVSCTARLDVY 1102
G YTV+A N G V ++VY
Sbjct: 8976 GTYTVTASNRLGSVFRNVHVEVY 8998
Score = 55.1 bits (131), Expect = 4e-07
Identities = 60/277 (21%), Positives = 110/277 (39%), Gaps = 45/277 (16%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F KL+ E V L+C ++ P V+WF +GKE+ + + I +G LI
Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKK-RMLI 5578
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
+ +A + D G+YTC G+D TS ++ D + + ++ + +T
Sbjct: 5579 LKKALKSDIGQYTC----DCGTDKTSGKL--------DIEDREIKLVRPLHSVEVMETET 5626
Query: 391 TSVSLTIGSSSPKTG---VTTAVIQPLSVPVQQ---VHSPTSYLCRPDGTTTAYFPPVFT 444
I A++Q +++ +HS + CR D T F
Sbjct: 5627 ARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANV 5686
Query: 445 KE----------------LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
K L++ V G+ +C + + V+W+ +G +++ S
Sbjct: 5687 KSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCEL-SYEDIPVEWYLKGKKLEPSD--- 5742
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARN 525
+ PRS ++ TL + + EDAG +A++
Sbjct: 5743 --KVVPRSEG---KVHTLTLRDVKLEDAGEVQLTAKD 5774
Score = 54.3 bits (129), Expect = 6e-07
Identities = 47/194 (24%), Positives = 82/194 (42%), Gaps = 13/194 (6%)
Query: 757 VDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 816
+++SG + V AP + K++ ++ G FTC + P + WFK G++
Sbjct: 4317 LNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE 4376
Query: 817 ISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV-------- 868
I +SD +I R SL + + D G YT A+N G +SCT L V
Sbjct: 4377 IY-ESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKK 4434
Query: 869 --QAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGK 926
+ + +R P+ V R R + E + + E+ +P + P V+E +
Sbjct: 4435 VRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKL-EKVKKPAVPEPPPPKPVEEVE 4493
Query: 927 LCRMDCKVSGLPTP 940
+ + + +P P
Sbjct: 4494 VPTVTKRERKIPEP 4507
Score = 54.3 bits (129), Expect = 6e-07
Identities = 59/258 (22%), Positives = 105/258 (40%), Gaps = 44/258 (17%)
Query: 773 NGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG 832
+G AP ++K G +C++ G P P I W++ GK++ +S Y + D
Sbjct: 24032 SGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSD-GR 24089
Query: 833 TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 892
T +L +D+G YT +A N G + + +L++QA +P HP
Sbjct: 24090 THTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQA---------TPQFHP------- 24133
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
P++E+++ G R+ G P P ++W G+ +
Sbjct: 24134 --------GYPLKEKYYG------------AVGSTLRLHVMYIGRPVPAMTW-FHGQKLL 24172
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSR-DAGIYTCIATNRAGQNSFSLELVVAAKEAHKP-- 1009
+S + + L+++ V + AG Y +N G L++ + K KP
Sbjct: 24173 QNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDK-PDKPTG 24231
Query: 1010 PVFIEK-LQNTGVADGYP 1026
P+ IE L+N+ V P
Sbjct: 24232 PIVIEALLKNSAVISWKP 24249
Score = 53.5 bits (127), Expect = 1e-06
Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 1/97 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
LTV+ G +D V G P P +SW+ DG ++P KM ++ N + +L + V +D+
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12866
Query: 980 GIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
G YT A N +G S +++L V K V I K+
Sbjct: 12867 GDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKM 12903
Score = 52.8 bits (125), Expect = 2e-06
Identities = 77/305 (25%), Positives = 118/305 (38%), Gaps = 60/305 (19%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
F L+ + EG C V+ K+ WFK+G +I KS Y I D L
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEVS-RENAKVKWFKNGTEIL-KSKKYEIVAD-GRVRKLVI 5846
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
T +D YT A + + SC ++ PHV
Sbjct: 5847 HDCTPEDIKTYTCDAKD--FKTSCNLNVVP----------------PHVE---------- 5878
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHK 958
FL+ DL V+E ++ R +C++S + W DG ++ +
Sbjct: 5879 --------------FLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAEIKKGKKYD 5923
Query: 959 MLVRENGVHSLIIEPVTSRDAGIYTC-IATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQ 1017
++ + V L+I D Y+C + T R S L V +EA VF + L
Sbjct: 5924 -IISKGAVRILVINKCLLDDEAEYSCEVRTART-----SGMLTVLEEEA----VFTKNLA 5973
Query: 1018 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKE 1077
N V++ ++L C V P ++ W K +E + T R + + I L+IQ A E
Sbjct: 5974 NIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEII-ETGRYEILTEGRKRI-LVIQNAHLE 6030
Query: 1078 DAGWY 1082
DAG Y
Sbjct: 6031 DAGNY 6035
Score = 52.8 bits (125), Expect = 2e-06
Identities = 31/94 (32%), Positives = 47/94 (50%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
P F E+L+N V L C+V G P P + W ++ + + + + + GY L
Sbjct: 24431 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24490
Query: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
+I T +DA Y V A N+ G VS TA L+V +
Sbjct: 24491 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEV 24524
Score = 52.4 bits (124), Expect = 2e-06
Identities = 34/100 (34%), Positives = 46/100 (46%), Gaps = 10/100 (10%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDS--PDFRILQKKPRSTA 498
P FT+ LQ+ V EG E + G P +V WFR G I S P +I R+
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA-- 63
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L I ++G ++ A N G ATSTA+L+V
Sbjct: 64 ------KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 51.6 bits (122), Expect = 4e-06
Identities = 65/271 (23%), Positives = 108/271 (39%), Gaps = 25/271 (9%)
Query: 277 LRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE 336
+++ EV E EC V+ P + W G E+ + +I +G LH LII
Sbjct: 2842 MKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQG-KLHQLIIMNTST 2899
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE---SLAFK---SRAGAMPQAQKKT 390
+D+ YT + N S T + + + D ++E ++ F+ + G + K
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP---VFTKEL 447
+ T +T T + +V T + T T Y F K +
Sbjct: 2960 VEIKST-DKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHI 3018
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
++ V E + + EC V P + VQW + E+Q + +I ++K + L+
Sbjct: 3019 KDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEK--------YVHRLL 3069
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
I T DAG +T A G STA+L V
Sbjct: 3070 IPSTRMSDAGKYTVVA----GGNVSTAKLFV 3096
Score = 50.8 bits (120), Expect = 7e-06
Identities = 51/270 (18%), Positives = 102/270 (37%), Gaps = 28/270 (10%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP+ ++++SQ V +GS + RV G P P W+ G ++ + I + ++ L
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCEL 2090
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG----------ASSTDSDSESLAFKSR 379
+I + +D+ A N +G ++ A + ++ + +++A
Sbjct: 2091 VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFEC 2150
Query: 380 AGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC----RPDGTT 435
+ P + K + + + + LS+ Y C + T
Sbjct: 2151 ETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKT 2210
Query: 436 TAYF-----PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
TA F KELQ+ V E LEC V ++ +W+ E++ + + I
Sbjct: 2211 TAKLIVEGAVVEFVKELQDIEVPESYSGELECIV-SPENIEGKWYHNDVELKSNGKYTIT 2269
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFT 520
++ R L + + ED G ++
Sbjct: 2270 SRRGRQ--------NLTVKDVTKEDQGEYS 2291
Score = 50.8 bits (120), Expect = 7e-06
Identities = 35/127 (27%), Positives = 63/127 (49%), Gaps = 3/127 (2%)
Query: 905 QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 964
+E+ P L P +T++ GK R++ V G P P W+ G+ S+H + + +
Sbjct: 12397 KEQLLPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWK-KGEDEVVTSSHLAVHKAD 12454
Query: 965 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA-AKEAHKPPVFIEKLQNTGVAD 1023
LII+ VT +D+G Y+ A N +G ++ +++VV A +PP I + +
Sbjct: 12455 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL 12514
Query: 1024 GYPVRLE 1030
+ + LE
Sbjct: 12515 SWHIPLE 12521
Score = 50.8 bits (120), Expect = 7e-06
Identities = 57/257 (22%), Positives = 97/257 (37%), Gaps = 55/257 (21%)
Query: 284 EGSRVYLECRVTG-NPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRY 342
EG V C++ + + +V W+ ++L N+ +I E G + L + + + D G Y
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDG-VAILYVKDITKLDDGTY 25142
Query: 343 TCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSP 402
C N G D++ AE+F++G E + R M + +++T ++ L
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGV------REVYDYYCRR-TMKKIKRRTDTMRL------- 25188
Query: 403 KTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLEC 462
L RP P FT L N G+ V
Sbjct: 25189 -------------------------LERP---------PEFTLPLYNKTAYVGENVRFGV 25214
Query: 463 RVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCS 522
+ P V W++ G +I+ + K + + + L I +D +T
Sbjct: 25215 TITVHPEPHVTWYKSGQKIKPGDN-----DKKYTFESDKGLYQLTINSVTTDDDAEYTVV 25269
Query: 523 ARNDYGSATSTAQLVVT 539
ARN YG + A+L VT
Sbjct: 25270 ARNKYGEDSCKAKLTVT 25286
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/95 (35%), Positives = 56/95 (58%), Gaps = 5/95 (5%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKK-ENESLTHSTDR 1056
E V AKE PP + Q T + G +R+E V G P P WKK E+E +T S
Sbjct: 12391 EGVYEAKEQLLPPKILMPEQIT-IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSS--H 12447
Query: 1057 VSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
+++H+ + I L+I+ T++D+G+Y+++A+N +G
Sbjct: 12448 LAVHKADSSSI-LIIKDVTRKDSGYYSLTAENSSG 12481
Score = 50.1 bits (118), Expect = 1e-05
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHS-TDRVSMHQDNHGYIC 1068
PVF+ K + +G R + +V+G P P+ FW + + + + T +V + +D G
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED--GTQS 1468
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISRH 1106
L+I AT D+G +TV A+N AG S + L V H
Sbjct: 1469 LIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEH 1506
Score = 49.7 bits (117), Expect = 2e-05
Identities = 41/158 (25%), Positives = 67/158 (42%), Gaps = 5/158 (3%)
Query: 205 LSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSA 264
L P ++ +L S S+SP+ M SP AR + R+ S
Sbjct: 1350 LEPVSRIRSLSPRSVSRSPIR----MSPARMSP-ARMSPARMSPARMSPGRRLEETDESQ 1404
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
L P F+ K S + EG + +V G P P WF +G+++ N ++ +
Sbjct: 1405 LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED 1464
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+LII A D+G +T +A N +G + S + +E
Sbjct: 1465 GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVE 1502
Score = 49.7 bits (117), Expect = 2e-05
Identities = 73/280 (26%), Positives = 110/280 (39%), Gaps = 29/280 (10%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F + L + EV+E + L C V+ P V W+ +E+ T +I EG L+I
Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRK-RILVIQ 6025
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFI-EGASSTDSDSESLAFKS--RAGAMPQAQKK 389
A +D G Y C S T +V + E A+ S ++L +A + K+
Sbjct: 6026 NAHLEDAGNYNCRLP----SSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKE 6081
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT-----SYLCRPDGTTTAYFPPVFT 444
+ V + ++G VI V V T +Y+ A V
Sbjct: 6082 SFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAHLTVIE 6141
Query: 445 K-----ELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
K L++T V E Q VV C V + +WFR I DS + ILQK
Sbjct: 6142 KLRIVVPLKDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQK------- 6193
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYG-SATSTAQLVV 538
+ + TL I + +D + S N G + S A L+V
Sbjct: 6194 -DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 6232
Score = 49.3 bits (116), Expect = 2e-05
Identities = 41/167 (24%), Positives = 69/167 (41%), Gaps = 22/167 (13%)
Query: 195 GESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDL----- 249
G + S DSG ++ + +++ ++D+ + E + P R Q ++L
Sbjct: 1719 GVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAH 1778
Query: 250 -----AVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRW 304
V ++K +P L +P R V EG CRVTG P P+V W
Sbjct: 1779 EGALTGVTTDQKEKQKPDIVL-YPEPVR---------VLEGETARFRCRVTGYPQPKVNW 1828
Query: 305 FCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSG 351
+ G+ + + ++ +G +H L I + DTG A NP G
Sbjct: 1829 YLNGQLIRKSKRFRVRYDG--IHYLDIVDCKSYDTGEVKVTAENPEG 1873
Score = 49.3 bits (116), Expect = 2e-05
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 8/98 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P KE+++ G+ L C++ G P ++W+R G E ++Q + +
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKE--------LIQSRKYKMSSD 24087
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
TL + ED G++TC A N+ G ++++L++
Sbjct: 24088 GRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLL 24125
Score = 49.3 bits (116), Expect = 2e-05
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 8/99 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE-IQDSPDFRILQKKPRSTAE 499
P F +EL+N V L C+V G P V+W+RQG E I D +RI + K
Sbjct: 24431 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFK------ 24484
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L+IA +DA ++ A N GS + TA L V
Sbjct: 24485 -GGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24522
Score = 48.1 bits (113), Expect = 4e-05
Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 5/145 (3%)
Query: 960 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFS-LELVVAAKEAHKPPVFIEKLQN 1018
+V E+ V + ++ ++S + A N G++ L + V AK+ P
Sbjct: 17764 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 17823
Query: 1019 TGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKED 1078
+ G +++E V+G P P I W K+ E L +T RV++ + + L I+ K+D
Sbjct: 17824 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT-RVNVEETATSTV-LHIKEGNKDD 17881
Query: 1079 AGWYTVSAKNEAGIVSCTARLDVYI 1103
G YTV+A N AG + T L V +
Sbjct: 17882 FGKYTVTATNSAG--TATENLSVIV 17904
Score = 47.8 bits (112), Expect = 6e-05
Identities = 64/261 (24%), Positives = 98/261 (37%), Gaps = 49/261 (18%)
Query: 619 VNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKD 678
+ GL+ G+ + + P E P+LA LG P R + TK
Sbjct: 8759 ITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYT------ERTKS 8812
Query: 679 AVIQDLERKLRFKEDLLNNGQPRLTYE-----------ERMARRLLGADSATVFNIQEPE 727
+ D +KE N G P Y ER+ +RL S V N+ E +
Sbjct: 8813 TITLD------WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQ 8866
Query: 728 EETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLK--- 784
E++V + + I E E L + V +Q +VP P +++L
Sbjct: 8867 M----YEFRVKAVNE--IGESEPSLPLNVV------IQDDEVP------PTIKLRLSVRG 8908
Query: 785 -HYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD----LDGTCSLHTT 839
K+ G PV V G P PKI W K+ I +D I ++ + L
Sbjct: 8909 DTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIP 8968
Query: 840 ASTLDDDGNYTIMAANPQGRI 860
+ +D G YT+ A+N G +
Sbjct: 8969 KAVREDKGTYTVTASNRLGSV 8989
Score = 47.8 bits (112), Expect = 6e-05
Identities = 40/145 (27%), Positives = 70/145 (48%), Gaps = 21/145 (14%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V+A N++G+S G P + + + +P + F + +QA DL
Sbjct: 17788 VKAYNEKGKSDPRVLGVPVIAKDLTI--------QPSLKLPFNTYSIQAGEDL------- 17832
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI-IEPVTSRDAGIYTCIA 986
+++ V G P P++SW DG+P++ + ++ V E +++ I+ D G YT A
Sbjct: 17833 -KIEIPVIGRPRPNISWVKDGEPLKQTT--RVNVEETATSTVLHIKEGNKDDFGKYTVTA 17889
Query: 987 TNRAGQNSFSLELVVAAKEAHKPPV 1011
TN AG + +L ++V K PPV
Sbjct: 17890 TNSAGTATENLSVIVLEKPG--PPV 17912
Score = 47.4 bits (111), Expect = 8e-05
Identities = 31/110 (28%), Positives = 47/110 (42%), Gaps = 5/110 (4%)
Query: 256 KSHPQ----PHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL 311
KS P+ P A P + + G + +E V G P P + W +G+ L
Sbjct: 17796 KSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL 17855
Query: 312 HNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
T + + E L I E +DD G+YT ATN +G+ T + V +
Sbjct: 17856 KQTTRVNVE-ETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 46.6 bits (109), Expect = 1e-04
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDD 338
S V G + +E ++G P P + W +G L T I + + DL TL I E +DD
Sbjct: 16741 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV-TDSLDLTTLSIKETHKDD 16799
Query: 339 TGRYTCLATNPSGSDTTSAEV 359
G+Y N G T S E+
Sbjct: 16800 GGQYGITVANVVGQKTASIEI 16820
Score = 46.2 bits (108), Expect = 2e-04
Identities = 48/182 (26%), Positives = 77/182 (42%), Gaps = 19/182 (10%)
Query: 925 GKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTC 984
G +C VS T +W DG +R H+ + + L I V DAG YTC
Sbjct: 4636 GSSAIFECLVSP-STAITTWMKDGSNIRESPKHRFIA-DGKDRKLHIIDVQLSDAGEYTC 4693
Query: 985 IATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQN-TGVADGYPVRLECRVLGVPPPQIFW 1043
+ + + + +LVV P F++ L+ V G P+ L C + + W
Sbjct: 4694 VLRLGNKEKTSTAKLVVE----ELPVRFVKTLEEEVTVVKGQPLYLSCELN--KERDVVW 4747
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLL----IQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
+K+ + + R+ G I L+ I A DAG YTV+ +N A + C++ +
Sbjct: 4748 RKDGKIVVEKPGRIVP-----GVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSSCV 4801
Query: 1100 DV 1101
V
Sbjct: 4802 KV 4803
Score = 46.2 bits (108), Expect = 2e-04
Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query: 997 LELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDR 1056
L + V AK+ PP F V G ++++ +G P P + W K+N L +T R
Sbjct: 15638 LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTT-R 15696
Query: 1057 VSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
V+ + + L I+ A +ED G Y V N AG
Sbjct: 15697 VNAESTENNSL-LTIKDACREDVGHYVVKLTNSAG 15730
Score = 45.8 bits (107), Expect = 2e-04
Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 12/138 (8%)
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRP-DSAHKMLVRENGVHSLIIE 972
LQ D V EG + +++ KVS L + + W DG+ V+P D H ++ +++ H L+IE
Sbjct: 2313 LQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQS--HMLLIE 2369
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
+T DAG Y+ +L L + + + I L++ V +G LEC+
Sbjct: 2370 DMTKEDAGNYSFTIP--------ALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECK 2421
Query: 1033 VLGVPPPQIFWKKENESL 1050
V + W +E +
Sbjct: 2422 VSVPDVTSVKWYLNDEQI 2439
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
AAP +K+ EVA G C + P R +WF G+E++ + I + +
Sbjct: 4335 AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR-SSKYISS 4393
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
L I D G YTC A+N GS + +A + +
Sbjct: 4394 LEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTGRYT 343
G LE V+G P P + W +GKEL T ++I D T L+ ++ D+G YT
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI--ADFSTNLVNKDSTRRDSGAYT 15036
Query: 344 CLATNPSG 351
ATNP G
Sbjct: 15037 LTATNPGG 15044
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G +RL V G PPP I W K+ L ++ Y L++ + DAG YT
Sbjct: 22964 GASLRLMVSVSGRPPPVITWSKQGIDLASR----AIIDTTESYSLLIVDKVNRYDAGKYT 23019
Query: 1084 VSAKNEAGIVSCTARLDVY 1102
+ A+N++G S T + VY
Sbjct: 23020 IEAENQSGKKSATVLVKVY 23038
Score = 45.4 bits (106), Expect = 3e-04
Identities = 84/380 (22%), Positives = 138/380 (36%), Gaps = 77/380 (20%)
Query: 760 SGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISP 819
+G+ + G + V G L + E F C VA NP K W +DGK +
Sbjct: 2560 AGENMTSGKLTVAGGA---ISKPLTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPL 2615
Query: 820 KSDHYTIQRDLDG-TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
++ I+ + DG L A+ LDD G YT A + + +L V+AV +
Sbjct: 2616 TNN---IRSESDGHKRRLIIAATKLDDIGEYTYKVATSK----TSAKLKVEAVKIKKTLK 2668
Query: 879 R------------SPSGHPHVRRPR------------------------SRSRDSGDENE 902
HP+V+ + R ++ +E
Sbjct: 2669 NLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDE 2728
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL----DGKPV------- 951
+ FR L A L V+ K+ + V+ L +++++ D PV
Sbjct: 2729 SVYG--FRLGRLGASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSV 2786
Query: 952 --RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP 1009
+P H+ LV E VH L+++ ++ DAG YT + GQ +L V K
Sbjct: 2787 EIKPSDKHR-LVSERKVHKLMLQNISPSDAGEYTAV----VGQLECKAKLFVETLHITK- 2840
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
++N V + EC V P ++ K E ++ + H L
Sbjct: 2841 -----TMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQ---L 2892
Query: 1070 LIQGATKEDAGWYTVSAKNE 1089
+I + ED+ YT N+
Sbjct: 2893 IIMNTSTEDSAEYTFVCGND 2912
Score = 44.7 bits (104), Expect = 5e-04
Identities = 80/363 (22%), Positives = 132/363 (36%), Gaps = 54/363 (14%)
Query: 263 SALHFPAAPRFIQKLRSQE---VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
S+ H PR I LR + V G +C ++ P V W+ +GK+L + +
Sbjct: 5688 SSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVP 5746
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI-EGASSTDSDSESLAFKS 378
EG +HTL + + +D G A + T A +F+ E E +
Sbjct: 5747 RSEG-KVHTLTLRDVKLEDAGEVQLTAKDFK----THANLFVKEPPVEFTKPLEDQTVEE 5801
Query: 379 RAGAMPQAQKKTTSVSLT-------IGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRP 431
A A+ + + + + I S V ++ L + +Y C
Sbjct: 5802 GATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861
Query: 432 DGTTTA----YFPP--VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSP 485
T+ PP F + L + V E ++ EC + +V+WF+ G+EI+
Sbjct: 5862 KDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGK 5920
Query: 486 DFRILQK---------KPRSTAEPEEICTLVIAE-----TFPEDAGIFTCSARNDYGSAT 531
+ I+ K K E E C + A T E+ +FT + N S T
Sbjct: 5921 KYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTSGMLTVLEEEAVFTKNLANIEVSET 5980
Query: 532 STAQLV--VTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNN 589
T +LV V+ E Y+ E I+ET E+ ++ I + N
Sbjct: 5981 DTIKLVCEVSKPGAEVIWYKGDEE--------------IIETGRYEILTEGRKRILVIQN 6026
Query: 590 PEL 592
L
Sbjct: 6027 AHL 6029
Score = 44.7 bits (104), Expect = 5e-04
Identities = 53/200 (26%), Positives = 88/200 (44%), Gaps = 32/200 (16%)
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH 886
++D D +HT A+ + + +T+ P ++ V AVN +G S S
Sbjct: 22885 EKDTDQWYRVHTNATIRNTE--FTV----PDLKMGQKYSFRVAAVNVKGMSEYS------ 22932
Query: 887 VRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDL----TVQEGKLCRMDCKVSGLPTPDL 942
+S E EP+ ER P L+ DL T++ G R+ VSG P P +
Sbjct: 22933 ---------ESIAEIEPV-ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVI 22981
Query: 943 SWQLDGKPVRPDSAHKMLVRENGVHSL-IIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+W G D A + ++ +SL I++ V DAG YT A N++G+ S ++ + V
Sbjct: 22982 TWSKQGI----DLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23037
Query: 1002 AAKEAHKPPVFIEKLQNTGV 1021
P V ++++ V
Sbjct: 23038 YDTPGPCPSVKVKEVSRDSV 23057
Score = 44.3 bits (103), Expect = 6e-04
Identities = 36/106 (33%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNT--GVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTD 1055
E V+A H P V ++ V G +R+ RV G P P I W KE + L
Sbjct: 11398 ESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE-K 11456
Query: 1056 RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
RV + QD + L I+ A + D G Y +SAKN +G +A ++V
Sbjct: 11457 RVDLIQD-LPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNV 11501
Score = 44.3 bits (103), Expect = 6e-04
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G + ++ V G P PRV WF +G E+ +++I G +L + +A D G
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST-SLFVRDATRDHRGV 21531
Query: 342 YTCLATNPSGSDTTSAEVFIE 362
YT A N SGS +V ++
Sbjct: 21532 YTVEAKNASGSAKAEIKVKVQ 21552
Score = 43.9 bits (102), Expect = 8e-04
Identities = 35/118 (29%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG--VADGYPVRLECRVLGVPPPQIFW 1043
A N G+ + S VVA + P + ++ L + + RL+ + G P P + W
Sbjct: 13460 AENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13519
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
KK + L T RVS+ + + L++ K DAG YT++ KN AG T + V
Sbjct: 13520 KKGEDPLATDT-RVSV-ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13575
Score = 43.9 bits (102), Expect = 8e-04
Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 8/136 (5%)
Query: 744 LISEIEYRLERSPVDESG-DEVQYGDVPV---ENGMAPFFEMKLKHYKIFEGMPVTFTCR 799
L S EY+ +E G + + VPV + + P ++ Y I G +
Sbjct: 17778 LSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIP 17837
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGR 859
V G P+P I W KDG+ + ++ ++ T LH DD G YT+ A N G
Sbjct: 17838 VIGRPRPNISWVKDGEPLK-QTTRVNVEETATSTV-LHIKEGNKDDFGKYTVTATNSAG- 17894
Query: 860 ISCTGRLMVQAVNQRG 875
+ T L V + + G
Sbjct: 17895 -TATENLSVIVLEKPG 17909
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
L V+ G R + G+P P W DG ++ D H + +N L I+ RD
Sbjct: 11023 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDT 11081
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y +N AG + ++ L V
Sbjct: 11082 GEYQITVSNAAGSKTVAVHLTV 11103
Score = 43.5 bits (101), Expect = 0.001
Identities = 28/79 (35%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSD-HYTIQRDLDGTCSLHTTASTLDDDGNY 849
G V V G P P + W KDG + P +QR+L C+L + D G+Y
Sbjct: 12813 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL---CTLELFSVNRKDSGDY 12869
Query: 850 TIMAANPQGRISCTGRLMV 868
TI A N G S T +L V
Sbjct: 12870 TITAENSSGSKSATIKLKV 12888
Score = 43.5 bits (101), Expect = 0.001
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
++ G+ R++ VSG P P + W DGK + + ++ + + +L+ + T RD+G
Sbjct: 14976 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15034
Query: 982 YTCIATNRAG 991
YT ATN G
Sbjct: 15035 YTLTATNPGG 15044
Score = 43.1 bits (100), Expect = 0.001
Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 18/145 (12%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V AVN++GRS P V + + P A +VQ G+
Sbjct: 16706 VVAVNEKGRSDPRSLAVPIVAK----------------DLVIEPDVKPAFSSYSVQVGQD 16749
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIAT 987
+++ +SG P P ++W DG P++ + + + +L I+ D G Y
Sbjct: 16750 LKIEVPISGRPKPTITWTKDGLPLK-QTTRINVTDSLDLTTLSIKETHKDDGGQYGITVA 16808
Query: 988 NRAGQNSFSLELVVAAK-EAHKPPV 1011
N GQ + S+E+V K + K PV
Sbjct: 16809 NVVGQKTASIEIVTLDKPDPPKGPV 16833
Score = 42.7 bits (99), Expect = 0.002
Identities = 59/256 (23%), Positives = 100/256 (39%), Gaps = 28/256 (10%)
Query: 277 LRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE 336
L Q VAE EC V NP + W +GK L T +I+ + G LIIA
Sbjct: 2580 LTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHLPLTNNIRSESD-GHKRRLIIAATKL 2637
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGA-------SSTDSDSESLAFKSRAGAMPQAQKK 389
DD G YT + TSA++ +E + T ++++ F P +
Sbjct: 2638 DDIGEYTYKV----ATSKTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVEL-THPNVKGV 2692
Query: 390 TTSVSLTIGSSSPKTGVTT-AVIQPLSVPVQQVHSPTSY---LCRPDGTTTAYFPPV-FT 444
+ + S+ K ++ I L + + + Y L R + + V
Sbjct: 2693 QWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKII 2752
Query: 445 KELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
K+ ++ E V E V + V+WF + EI+ S R++ ++ ++
Sbjct: 2753 KKPKDVTALENATVAFEVSV-SHDTVPVKWFHKSVEIKPSDKHRLVSER--------KVH 2803
Query: 505 TLVIAETFPEDAGIFT 520
L++ P DAG +T
Sbjct: 2804 KLMLQNISPSDAGEYT 2819
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/121 (30%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG---VADGYPVRLECRVLGVPPPQIF 1042
A N AG+ V E +PP + G + G +R+ V G P P
Sbjct: 8581 AVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8640
Query: 1043 WKKENESLTHSTDRVSMHQDNHGYIC-LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
W KE L DRV + DN G L+I+ A ++D G Y ++A N G AR++V
Sbjct: 8641 WTKEEGEL--DKDRVVI--DNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8696
Query: 1102 Y 1102
+
Sbjct: 8697 F 8697
Score = 42.7 bits (99), Expect = 0.002
Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELV--VAAKEAHKPPVFIEKLQNTGVAD---G 1024
II +T + A N G S E+V + +++ PV L+ T V G
Sbjct: 20331 IISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAG 20390
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
V+L + G P P I W K+++ L T+ + ++ +LI+ A + ++G Y +
Sbjct: 20391 TSVKLRAGISGKPAPTIEWYKDDKEL--QTNALVCVENTTDLASILIKDADRLNSGCYEL 20448
Query: 1085 SAKNEAGIVSCTARLDV 1101
+N G S T R+ +
Sbjct: 20449 KLRNAMGSASATIRVQI 20465
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
I G + V G P P++ WFKDG +I + + D+ G+ SL +T D G
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI--TDVLGSTSLFVRDATRDHRG 21530
Query: 848 NYTIMAANPQGRISCTGRLMVQ 869
YT+ A N G ++ VQ
Sbjct: 21531 VYTVEAKNASGSAKAEIKVKVQ 21552
Score = 42.4 bits (98), Expect = 0.002
Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 11/105 (10%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G ++ +E V G P P +W E+ + + +H + LII + D+G
Sbjct: 12413 IKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVH-KADSSSILIIKDVTRKDSGY 12471
Query: 342 YTCLATNPSGSDTTSAEVFIEGA----------SSTDSDSESLAF 376
Y+ A N SG+DT +V + A S D+D+ SL++
Sbjct: 12472 YSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSW 12516
Score = 42.0 bits (97), Expect = 0.003
Identities = 41/146 (28%), Positives = 60/146 (41%), Gaps = 19/146 (13%)
Query: 402 PKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAY----FPPVFTKELQNTAVAEGQV 457
P GV P+ +++ + PD Y P F KE+++ + E +
Sbjct: 4575 PIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEF 4634
Query: 458 V----VLECRVRGAPPLQVQWFRQGSEIQDSPDFR-ILQKKPRSTAEPEEICTLVIAETF 512
V + EC V + + W + GS I++SP R I K R L I +
Sbjct: 4635 VGSSAIFECLVSPSTAITT-WMKDGSNIRESPKHRFIADGKDRK---------LHIIDVQ 4684
Query: 513 PEDAGIFTCSARNDYGSATSTAQLVV 538
DAG +TC R TSTA+LVV
Sbjct: 4685 LSDAGEYTCVLRLGNKEKTSTAKLVV 4710
Score = 42.0 bits (97), Expect = 0.003
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A P F KL + E + L+C V+ + V+WF +G+E+ +P I + G
Sbjct: 5164 ADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSPKYSIKAD-GLRRI 5220
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
L I +A D G Y C G+D T A V +E
Sbjct: 5221 LKIKKADLKDKGEYVC----DCGTDKTKANVTVE 5250
Score = 42.0 bits (97), Expect = 0.003
Identities = 61/251 (24%), Positives = 94/251 (37%), Gaps = 50/251 (19%)
Query: 783 LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 842
LK ++ E V F C V K WF++ + I S + +Q+DL +L +
Sbjct: 6149 LKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDL--VYTLRIRDAH 6205
Query: 843 LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENE 902
LDD NY V N RG + +S + N
Sbjct: 6206 LDDQANYN-----------------VSLTNHRGENVKSAA------------------NL 6230
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
++E R ++ D+ E K CKV+ L L W +G+ V D+ V
Sbjct: 6231 IVEEEDLR--IVEPLKDIETMEKKSVTFWCKVNRL-NVTLKWTKNGEEVPFDNRVSYRV- 6286
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVA 1022
+ H L I+ D G Y I T AGQ+ EL++ P F+E L++ V
Sbjct: 6287 DKYKHMLTIKDCGFPDEGEY--IVT--AGQDKSVAELLI----IEAPTEFVEHLEDQTVT 6338
Query: 1023 DGYPVRLECRV 1033
+ C++
Sbjct: 6339 EFDDAVFSCQL 6349
Score = 42.0 bits (97), Expect = 0.003
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFED 337
R Q + G + L + G P P+V W E ++ I + G L I A +
Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLE---IRNAAHE 10785
Query: 338 DTGRYTCLATNPSGSDTTSAEVFI 361
D G Y+ NP+GS T S +V +
Sbjct: 10786 DGGIYSLTVENPAGSKTVSVKVLV 10809
Score = 42.0 bits (97), Expect = 0.003
Identities = 42/170 (24%), Positives = 73/170 (42%), Gaps = 13/170 (7%)
Query: 939 TPDLSWQLDGKPVRPDS---AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSF 995
+P+LS+ ++ + D HK ++E +++ + N G++ +
Sbjct: 11633 SPNLSYHVERRLKGSDDWERVHKGSIKET---HYMVDRCVENQIYEFRVQTKNEGGESDW 11689
Query: 996 SLELVVAAKEAHKPPVFIEKLQNT-GVADGYPVRLECRVLGVPPPQIFWKKENES--LTH 1052
V KE + PV KL V G +RLE V G P P++ W K+ ++ LT
Sbjct: 11690 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11749
Query: 1053 STD-RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
S ++ D+ + + A + D G Y V+A N AG A ++V
Sbjct: 11750 SPRVKIDTRADSSKF---SLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 3/123 (2%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNS-FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
+I +T + ++ +A N G++ SL + + AK+ P + V G ++
Sbjct: 16692 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 16751
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
+E + G P P I W K+ L +T R+++ D+ L I+ K+D G Y ++ N
Sbjct: 16752 IEVPISGRPKPTITWTKDGLPLKQTT-RINV-TDSLDLTTLSIKETHKDDGGQYGITVAN 16809
Query: 1089 EAG 1091
G
Sbjct: 16810 VVG 16812
Score = 41.6 bits (96), Expect = 0.004
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSR- 977
D+ V EG+ + +P P +SW DGK V+ ++ ++ ++ + + + + P + R
Sbjct: 7898 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK--ASDRLTMKNDHISAHLEVPKSVRA 7955
Query: 978 DAGIYTCIATNRAGQNSFSLELVV 1001
DAGIYT N+ G + S+ + V
Sbjct: 7956 DAGIYTITLENKLGSATASINVKV 7979
Score = 41.6 bits (96), Expect = 0.004
Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
P + KE V EG V + +++G P + WF+ + D+ + +L +
Sbjct: 9621 PSIDLKEFME--VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLV 9677
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ CTLVI ++ D G++T +A N+ G+A+ +L V
Sbjct: 9678 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9716
Score = 41.6 bits (96), Expect = 0.004
Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 12/100 (12%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE------- 972
+ V+EG + K+ G+P P L+W P +PD+ +L + V+ L+++
Sbjct: 9629 MEVEEGTNVNIVAKIKGVPFPTLTW-FKAPPKKPDNKEPVLY-DTHVNKLVVDDTCTLVI 9686
Query: 973 PVTSR-DAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV 1011
P + R D G+YT A N G S + L V + PPV
Sbjct: 9687 PQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPG--PPV 9724
Score = 41.6 bits (96), Expect = 0.004
Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 4/82 (4%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL-IQGATKEDA 1079
V G V L+ V G P P + WKK+ +L + + M + +C L + ++D+
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRN--LCTLELFSVNRKDS 12866
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G YT++A+N +G S T +L V
Sbjct: 12867 GDYTITAENSSGSKSATIKLKV 12888
Score = 41.2 bits (95), Expect = 0.005
Identities = 35/149 (23%), Positives = 64/149 (42%), Gaps = 17/149 (11%)
Query: 868 VQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL 927
V AVN++GRS G P + R E +P E F ++A L
Sbjct: 18871 VAAVNEKGRSDPRQLGVPVIAR--------DIEIKPSVELPFHTFNVKAREQL------- 18915
Query: 928 CRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIAT 987
++D G P ++W+ DG+ ++ ++ + V SL I+ + D G Y +
Sbjct: 18916 -KIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 18973
Query: 988 NRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
N AG + + ++V + P+ I+++
Sbjct: 18974 NSAGSITVPITIIVLDRPGPPGPIRIDEV 19002
Score = 41.2 bits (95), Expect = 0.005
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 7/106 (6%)
Query: 1000 VVAAKEAHKPPVFI---EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDR 1056
++ ++ + PP+ E + G +R++ V G P P++ W K+ + R
Sbjct: 21449 IIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEK---R 21505
Query: 1057 VSMH-QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
++M D G L ++ AT++ G YTV AKN +G ++ V
Sbjct: 21506 MNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21551
Score = 41.2 bits (95), Expect = 0.005
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 1/79 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
GS ++ ++G P P+V W E L T + I D TL + ++ D+GRY
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYFL 22223
Query: 345 LATNPSGSDTTSAEVFIEG 363
N +G T S V + G
Sbjct: 22224 TLENTAGVKTFSVTVVVIG 22242
Score = 40.8 bits (94), Expect = 0.007
Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 20/205 (9%)
Query: 678 DAVIQDLERK---LRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQE 734
D + D RK + +K N G P + Y M +G + N + ++ +
Sbjct: 7793 DLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP--VGTEKWMRVNSRPIKD----LK 7846
Query: 735 YKVSSCEQRLISEIEYRLERSPVDESG----DEVQYGDVPVENGMAPFFEMKLKHYKIFE 790
+KV E+ ++ + EY L V+ G E+ V + P +++ + E
Sbjct: 7847 FKV---EEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIE 7903
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G ++ P P + W KDGK++ SD T++ D + L S D G YT
Sbjct: 7904 GEKLSIPVPFRAVPVPTVSWHKDGKEVK-ASDRLTMKND-HISAHLEVPKSVRADAGIYT 7961
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
I N G S T + V+ + G
Sbjct: 7962 ITLENKLG--SATASINVKVIGLPG 7984
Score = 40.8 bits (94), Expect = 0.007
Identities = 32/106 (30%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Query: 998 ELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRV 1057
E VVA KP + +E + V +G + + VP P + W K+ + + S DR+
Sbjct: 7879 ENVVAKDPDCKPTIDLET-HDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKAS-DRL 7936
Query: 1058 SMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
+M D H L + + + DAG YT++ +N+ G S TA ++V +
Sbjct: 7937 TMKND-HISAHLEVPKSVRADAGIYTITLENKLG--SATASINVKV 7979
Score = 40.8 bits (94), Expect = 0.007
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P E + V EG+ + + R P V W + G E++ S R+ K +A
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD--RLTMKNDHISAH- 7946
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L + ++ DAGI+T + N GSAT++ + V
Sbjct: 7947 -----LEVPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 40.8 bits (94), Expect = 0.007
Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 8/100 (8%)
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFK------DGKQISPKSDHYTIQR 828
M P ++K + ++ EG V ++ G P P + WFK D K+ H +
Sbjct: 9619 MPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN-KL 9676
Query: 829 DLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
+D TC+L S D G YTI A N G S RL V
Sbjct: 9677 VVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9716
Score = 40.4 bits (93), Expect = 0.009
Identities = 52/218 (23%), Positives = 83/218 (38%), Gaps = 51/218 (23%)
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
+GG T + EA + T R+ + T +E ++ ++ E F+ RA
Sbjct: 23164 DGGSRLTGYVLEACKAGTERWMKVVT--------LKPTVLEHTVTSLNEGEQYLFRIRA- 23214
Query: 382 AMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPP 441
Q +K G S P+ VT +Q L V PT L
Sbjct: 23215 ---QNEK---------GVSEPRETVTAVTVQDLRV------LPTIDLS------------ 23244
Query: 442 VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
T + V G+ V L + G PP WF GS++++S R T E
Sbjct: 23245 --TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRES---------ERVTVETH 23293
Query: 502 -EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ L I ET D G +T +N G+ + T ++++
Sbjct: 23294 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVII 23331
Score = 40.0 bits (92), Expect = 0.012
Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G T R +G PKPK+ WFKD + D T + T +L + D G Y
Sbjct: 10336 GEAFALTGRYSGKPKPKVSWFKDEADV--LEDDRTHIKTTPATLALEKIKAKRSDSGKYC 10393
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
++ N G S G V V++ G
Sbjct: 10394 VVVENSTG--SRKGFCQVNVVDRPG 10416
Score = 39.7 bits (91), Expect = 0.016
Identities = 74/339 (21%), Positives = 122/339 (35%), Gaps = 77/339 (22%)
Query: 758 DESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQI 817
D+S E+ + P E F L+ + E F+C+++ K + W+++G++I
Sbjct: 6313 DKSVAELLIIEAPTE------FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNGREI 6365
Query: 818 SPKSDHYTIQRDLDGTCSLHTTA---STLDDDGNYTIMAANPQGRISCTGRLMVQAVNQR 874
+ Y ++D S+H LDD+ Y + + R RL V+ +
Sbjct: 6366 K-EGKKYKFEKD----GSIHRLIIKDCRLDDECEYACGVEDRKSR----ARLFVEEI--- 6413
Query: 875 GRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRP--HFLQAPGDLTVQEGKLCRMDC 932
P++ RP L+APG V +L +
Sbjct: 6414 ----------------------------PVE--IIRPPQDILEAPGADVVFLAELNKDKV 6443
Query: 933 KVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQ 992
+V W + V H+M+ E +H L I + RD G Y IA ++ +
Sbjct: 6444 EVQ--------WLRNNMVVVQGDKHQMM-SEGKIHRLQICDIKPRDQGEYRFIAKDKEAR 6494
Query: 993 NSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTH 1052
L K A Q+ V G P+ + P + W KENE L+
Sbjct: 6495 AKLELAAAPKIKTAD---------QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLST 6545
Query: 1053 STDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
T + Q + I A K D G Y + +N+ G
Sbjct: 6546 KTIDTTAEQTS-----FRILEAKKGDKGRYKIVLQNKHG 6579
Score = 39.7 bits (91), Expect = 0.016
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
++ G + + VTG P P W E EL D + G LII +A D G
Sbjct: 8618 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDK--DRVVIDNVGTKSELIIKDALRKDHG 8675
Query: 341 RYTCLATNPSGSDTTSAEV 359
RY ATN GS +A V
Sbjct: 8676 RYVITATNSCGSKFAAARV 8694
Score = 39.7 bits (91), Expect = 0.016
Identities = 41/146 (28%), Positives = 60/146 (41%), Gaps = 24/146 (16%)
Query: 865 RLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQE 924
R V+AVN+ G S P + D +E E + + A L +
Sbjct: 9281 RFRVKAVNEAGES------EPSDTTGEIPATDIQEEPEVFID-------IGAQDCLVCKA 9327
Query: 925 GKLCRMDCKVSGLPTPDLSWQLDGKPVR--PDSAH------KMLVRENGVHSLIIEPVTS 976
G R+ + G PTP SW+ DGK + D H ++ EN S+II P
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENS--SVIIIPECK 9385
Query: 977 RD-AGIYTCIATNRAGQNSFSLELVV 1001
R G Y+ A N+AGQ + + + V
Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKV 9411
Score = 39.7 bits (91), Expect = 0.016
Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 9/138 (6%)
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF-----IEKLQNTGVADG 1024
++ +T + + +A N AG+++ V KE P +KL D
Sbjct: 14526 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDN 14585
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
+++E VLG P P + WKK + + T RV+ I L I + D+G Y +
Sbjct: 14586 --IKVEIPVLGRPKPTVTWKK-GDQILKQTQRVNFETTATSTI-LNINECVRSDSGPYPL 14641
Query: 1085 SAKNEAGIVSCTARLDVY 1102
+A+N G V + V+
Sbjct: 14642 TARNIVGEVGDVITIQVH 14659
Score = 39.7 bits (91), Expect = 0.016
Identities = 36/125 (28%), Positives = 61/125 (48%), Gaps = 7/125 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P + ++ K ++T V G +++ + G
Sbjct: 16014 FRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGK 16073
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
P P I W K ++ L++ T R+ + + L ++ A + D+G Y + AKN AG S T
Sbjct: 16074 PIPTIQWIKGDQELSN-TARLEIKSTDFA-TSLSVKDAVRVDSGNYILKAKNVAGERSVT 16131
Query: 1097 ARLDV 1101
+ V
Sbjct: 16132 VNVKV 16136
Score = 39.3 bits (90), Expect = 0.021
Identities = 42/174 (24%), Positives = 69/174 (39%), Gaps = 12/174 (6%)
Query: 688 LRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISE 747
L+++ + G P L+Y + RRL G+D + +E Y V C + I
Sbjct: 11622 LKWRRPDYDGGSPNLSYH--VERRLKGSDDWERVHKGSIKET----HYMVDRCVENQI-- 11673
Query: 748 IEYRLERSPVDESGDEVQYGDVPVENGMA-PFFEMKLKHY-KIFEGMPVTFTCRVAGNPK 805
E+R++ D V+ +V V+ + P ++KL + G + V G P
Sbjct: 11674 YEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPF 11733
Query: 806 PKIYWFKDGKQIS-PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQG 858
P++ W KD +S I D + T + D G Y + A N G
Sbjct: 11734 PEVAWTKDKDATDLTRSPRVKIDTRADSS-KFSLTKAKRSDGGKYVVTATNTAG 11786
Score = 39.3 bits (90), Expect = 0.021
Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI-IEPVTSRD 978
+ V+ G++ +++ ++G P P +SW DG + + +++ +N H+L+ ++ RD
Sbjct: 19302 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN--HTLLTVKDCIRRD 19359
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAK 1004
G Y N AG S ++ V K
Sbjct: 19360 TGQYVLTLKNVAGTRSVAVNCKVLDK 19385
Score = 38.9 bits (89), Expect = 0.027
Identities = 63/282 (22%), Positives = 102/282 (36%), Gaps = 24/282 (8%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
I L+ V EG++ LEC+V+ V+W+ +++ +Q + G L+I
Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK-GTKQRLVINR 2460
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASS-TDSDSESLAFK---SRAGAMPQAQ 387
D G Y + + S E I G T ++++++ F+ S +G
Sbjct: 2461 THASDEGPYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWN 2520
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPV----F 443
K + SS I L+V Y T+ V
Sbjct: 2521 FKDKEIK----PSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAI 2576
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
+K L + VAE Q V EC V P + +W R G + L RS ++ +
Sbjct: 2577 SKPLTDQTVAESQEAVFECEVAN-PDSKGEWLRDGKHLP-------LTNNIRSESDGHK- 2627
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTEN 545
L+IA T +D G +T SA + V +N
Sbjct: 2628 RRLIIAATKLDDIGEYTYKVATSKTSAKLKVEAVKIKKTLKN 2669
Score = 38.9 bits (89), Expect = 0.027
Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 10/104 (9%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWF------CEGKE--LHNTPDIQI 319
P P I EV EG+ V + ++ G P P + WF + KE L++T ++
Sbjct: 9617 PDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKL 9676
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
+ D TL+I ++ DTG YT A N G+ + + + G
Sbjct: 9677 VVD--DTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9718
Score = 38.9 bits (89), Expect = 0.027
Identities = 32/125 (25%), Positives = 50/125 (40%), Gaps = 22/125 (17%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V GQ + + RV+G P + W ++G + ++Q PR L I E
Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPR--------VELQIKEA 11474
Query: 512 FPEDAGIFTCSARNDYGSATSTA------------QLVVTSANTENC--SYESMGESNND 557
D G + SA+N G A +A L VT+ ENC S+E+ ++
Sbjct: 11475 VRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGS 11534
Query: 558 HFQHF 562
+F
Sbjct: 11535 EITNF 11539
Score = 38.9 bits (89), Expect = 0.027
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F TV G+ ++D G PTP ++W D P++ + EN L
Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENN-SLLT 15709
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
I+ D G Y TN AG+ +L ++V K
Sbjct: 15710 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15743
Score = 38.9 bits (89), Expect = 0.027
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 768 DVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ 827
D+ +E + P F Y + G + ++G PKP I W KDG + ++ +
Sbjct: 16728 DLVIEPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINVT 16782
Query: 828 RDLDGTCSLHTTASTLDDDGNYTIMAANPQGR 859
LD T +L + DD G Y I AN G+
Sbjct: 16783 DSLDLT-TLSIKETHKDDGGQYGITVANVVGQ 16813
Score = 38.9 bits (89), Expect = 0.027
Identities = 35/139 (25%), Positives = 50/139 (35%), Gaps = 24/139 (17%)
Query: 227 QGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGS 286
+ + E+ V P QDL V P +H PA G
Sbjct: 23213 RAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPA---------------GR 23257
Query: 287 RVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT----LIIAEAFEDDTGRY 342
V L + G P P WF G +L + + + + HT L I E DTG Y
Sbjct: 23258 PVELVIPIAGRPPPAASWFFAGSKLRESERVTV-----ETHTKVAKLTIRETTIRDTGEY 23312
Query: 343 TCLATNPSGSDTTSAEVFI 361
T N +G+ + + +V I
Sbjct: 23313 TLELKNVTGTTSETIKVII 23331
Score = 38.5 bits (88), Expect = 0.036
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 7/82 (8%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKE-------LHNTPDIQIHCEGGDLHTLIIAEAFED 337
GS++ + + G PTP+ W +GK +H+ P+ + +II E
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9387
Query: 338 DTGRYTCLATNPSGSDTTSAEV 359
TG+Y+ A N +G T + V
Sbjct: 9388 HTGKYSITAKNKAGQKTANCRV 9409
Score = 38.5 bits (88), Expect = 0.036
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 13/129 (10%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLE---LVVAAKEAHKPPVFIE-KLQNTGVAD-GY 1025
+ +T A + IA N AG S E + + P + ++ K ++T + G
Sbjct: 14921 VSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGE 14980
Query: 1026 PVRLECRVLGVPPPQIFWKKENESLTHSTD---RVSMHQDNHGYICLLIQGATKEDAGWY 1082
RLE V G PPP + W K+ + L + +++ N L+ + +T+ D+G Y
Sbjct: 14981 AFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTN-----LVNKDSTRRDSGAY 15035
Query: 1083 TVSAKNEAG 1091
T++A N G
Sbjct: 15036 TLTATNPGG 15044
Score = 38.5 bits (88), Expect = 0.036
Identities = 37/159 (23%), Positives = 65/159 (40%), Gaps = 18/159 (11%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V G+ + ++G P P SW G +R +S + V L I T RD G
Sbjct: 23253 VPAGRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTVETHTKVAKLTIRETTIRDTGE 23311
Query: 982 YTCIATNRAGQNSFSLELVVAAKEAHKP-PVFIEKLQNTGVADGY-PVRLECRVLGVPPP 1039
YT N G S ++++++ K P+ I+++ T + + P L+ G P
Sbjct: 23312 YTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPL 23367
Query: 1040 QIF-----------WKKENESLTHSTDRVSMHQDNHGYI 1067
+ W +ES+T ST + + + + Y+
Sbjct: 23368 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYV 23406
Score = 38.1 bits (87), Expect = 0.046
Identities = 59/300 (19%), Positives = 106/300 (35%), Gaps = 48/300 (16%)
Query: 79 PSHKETKLGEHASRRPQDNRSTPVQPLAEKQTKSISSPVSKRKPAMSPL--LTRPSYIRS 136
P KE + + R+ + V+P K+ + + P P P+ + P+ +
Sbjct: 4444 PEPKEEVVLKSVLRKRPEEEEPKVEP---KKLEKVKKPAVPEPPPPKPVEEVEVPTVTKR 4500
Query: 137 LRKAE--------KRGAKTPSTNVKPKTPHQRKGGPQSQLCDKAANLIEELTSIFKAAKP 188
RK K P+ KPK + K + + + +T K
Sbjct: 4501 ERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKA 4560
Query: 189 RNRSPNGESSSPDSGYLS-PKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQ 247
++P E++ P PK PS + E ER PG+
Sbjct: 4561 EAKAPKEEAAKPKGPIKGVPKKTPSPI--------------EAERRKLRPGSG------- 4599
Query: 248 DLAVPHNRKSHPQPHSALHFPAAP-RFIQKLRSQEVAE----GSRVYLECRVTGNPTPRV 302
K + A P +F+++++ + E GS EC V+ + T
Sbjct: 4600 ------GEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPS-TAIT 4652
Query: 303 RWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
W +G + +P + +G D L I + D G YTC+ + T++A++ +E
Sbjct: 4653 TWMKDGSNIRESPKHRFIADGKD-RKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 4711
Score = 38.1 bits (87), Expect = 0.046
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 8/114 (7%)
Query: 982 YTCIATNRAGQNSFS-LELVVAAKEAHKPPVFI---EKLQNTGVADGYPVRLECRVLGVP 1037
+ +A N AG++ + + V K+ +PP I + + G +RL + GVP
Sbjct: 10690 FRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVP 10749
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
P++ WKKE+ + R+ + L I+ A ED G Y+++ +N AG
Sbjct: 10750 FPKVTWKKEDRD-APTKARIDVTPVGSK---LEIRNAAHEDGGIYSLTVENPAG 10799
Score = 38.1 bits (87), Expect = 0.046
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G+ V L+ V G P P V W +G L I++ + +L TL + D+G
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQ-RNLCTLELFSVNRKDSGD 12868
Query: 342 YTCLATNPSGSDTTSAEV 359
YT A N SGS + + ++
Sbjct: 12869 YTITAENSSGSKSATIKL 12886
Score = 38.1 bits (87), Expect = 0.046
Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Query: 920 LTVQEGKLCRMDC-KVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
LT++ G ++ + G P P SW GK +RP ++ L I+ T +D
Sbjct: 13891 LTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKD 13949
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
AG YT ATN G +++ V PV I +
Sbjct: 13950 AGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNV 13987
Score = 38.1 bits (87), Expect = 0.046
Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ GS + L+ V G P P++ W KEL + + G T +I D+G+
Sbjct: 22562 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYT-GKRATAVIKFCDRSDSGK 22620
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SG+ S V
Sbjct: 22621 YTLTVKNASGTKAVSVMV 22638
Score = 37.7 bits (86), Expect = 0.061
Identities = 50/218 (22%), Positives = 81/218 (37%), Gaps = 46/218 (21%)
Query: 783 LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAST 842
L K+ EG V +V+ + W KDG+++ P SD I D L T
Sbjct: 2316 LSDQKVCEGDIVQLEVKVSLESVEGV-WMKDGQEVQP-SDRVHIVIDKQSHMLL-IEDMT 2372
Query: 843 LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENE 902
+D GNY+ P +S +GR+ V +V D
Sbjct: 2373 KEDAGNYSFTI--PALGLSTSGRVSVYSV---------------------------DVIT 2403
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
P++ D+ V EG ++CKVS + W L+ + ++PD + +V+
Sbjct: 2404 PLK-------------DVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVK 2450
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 1000
L+I + D G Y I + S+E +
Sbjct: 2451 -GTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVEKI 2487
Score = 37.7 bits (86), Expect = 0.061
Identities = 23/87 (26%), Positives = 42/87 (48%), Gaps = 8/87 (9%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G V L+ V G P V W + G+ ++ + ++ ++ +CTL +
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR--------NLCTLELFSV 12861
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVV 538
+D+G +T +A N GS ++T +L V
Sbjct: 12862 NRKDSGDYTITAENSSGSKSATIKLKV 12888
Score = 37.4 bits (85), Expect = 0.079
Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWF--CEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDT 339
V G + LE V G P P V W + +L +P ++I D + +A D
Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTR-ADSSKFSLTKAKRSDG 11774
Query: 340 GRYTCLATNPSGSDTTSAEV 359
G+Y ATN +GS A V
Sbjct: 11775 GKYVVTATNTAGSFVAYATV 11794
Score = 37.0 bits (84), Expect = 0.10
Identities = 47/218 (21%), Positives = 90/218 (41%), Gaps = 34/218 (15%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G+ V + V G P +++W + + I+ D + K+ S +E + L I +
Sbjct: 8913 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAK--TELSIPKA 8970
Query: 512 FPEDAGIFTCSARNDYGSA------------TSTAQLVVTSANTENC--SYESMGESNND 557
ED G +T +A N GS + L VT E+C ++++ ++
Sbjct: 8971 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGS 9030
Query: 558 HFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSR 617
H+ +++ AS+K +E ++V N A++ ++ + NG + R
Sbjct: 9031 EITHY-----VIDKRD---ASRKKAEWEEVTN-------TAVEKRYGIWKLIPNGQYEFR 9075
Query: 618 GVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKL 655
+N S++ V+ P + P P KPK+
Sbjct: 9076 --VRAVNKYGISDECKSDKVVIQDPYRLPGP-PGKPKV 9110
Score = 37.0 bits (84), Expect = 0.10
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL-IQGATKEDAGWY 1082
G +RL V G PPP+I W K N +L DR+ + + + L + K DAG Y
Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPNVNL---RDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13267
Query: 1083 TVSAKNEAG 1091
++ +N G
Sbjct: 13268 ILTLENSCG 13276
Score = 37.0 bits (84), Expect = 0.10
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 923 QEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH-SLIIEPVTSRDAGI 981
+E R+ + G P P +SW+ P+ D+ ++ V + V+ +LI+ DAG
Sbjct: 13498 KENSNFRLKIPIKGKPAPSVSWKKGEDPLATDT--RVSVESSAVNTTLIVYDCQKSDAGK 13555
Query: 982 YTCIATNRAGQNSFSLELVVAAK 1004
YT N AG ++ + V K
Sbjct: 13556 YTITLKNVAGTKEGTISIKVVGK 13578
Score = 37.0 bits (84), Expect = 0.10
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQG 858
V+G P P + W KDGK++ + + D + +L ST D G YT+ A NP G
Sbjct: 14988 VSGRPPPTMEWSKDGKELEGTAKLEI--KIADFSTNLVNKDSTRRDSGAYTLTATNPGG 15044
Score = 37.0 bits (84), Expect = 0.10
Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 10/121 (8%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ R++ V G P P + W K + +SA + + LI++ D
Sbjct: 17138 IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIE-ESARCEIKNTDFKALLIVKDAIRIDG 17196
Query: 980 GIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPP 1039
G Y A+N AG SF + + V + PP +Q TGV +C + PP
Sbjct: 17197 GQYILRASNVAGSKSFPVNVKVLDRPG--PPE--GPVQVTGVTSE-----KCSLTWSPPL 17247
Query: 1040 Q 1040
Q
Sbjct: 17248 Q 17248
Score = 37.0 bits (84), Expect = 0.10
Identities = 29/125 (23%), Positives = 57/125 (45%), Gaps = 3/125 (2%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNS-FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
I +T+ + ++ A N G++ L + V A++ P V +++
Sbjct: 18858 ISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKI 18917
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
+ G P + W+K+ ++L +T RV++ + L I+ A+KED G Y + N
Sbjct: 18918 DVPFKGRPQATVNWRKDGQTLKETT-RVNV-SSSKTVTSLSIKEASKEDVGTYELCVSNS 18975
Query: 1090 AGIVS 1094
AG ++
Sbjct: 18976 AGSIT 18980
Score = 37.0 bits (84), Expect = 0.10
Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 14/86 (16%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLT-----HSTDRVSMHQDNHGYICLLIQGAT 1075
V G +RL G P P W K + +L+ H+TD S L ++
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFST---------LTVENCN 21922
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDV 1101
+ DAG YT++ +N +G S T + V
Sbjct: 21923 RNDAGKYTLTVENNSGSKSITFTVKV 21948
Score = 37.0 bits (84), Expect = 0.10
Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 2/88 (2%)
Query: 781 MKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA 840
M K + G PV +AG P P WF G ++ +S+ T++ L
Sbjct: 23246 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTVETHTK-VAKLTIRE 23303
Query: 841 STLDDDGNYTIMAANPQGRISCTGRLMV 868
+T+ D G YT+ N G S T ++++
Sbjct: 23304 TTIRDTGEYTLELKNVTGTTSETIKVII 23331
Score = 36.6 bits (83), Expect = 0.14
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 10/178 (5%)
Query: 193 PNGESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVP 252
P +SPD G+ N + L+ + + +++ E E V C Q+ + P
Sbjct: 12040 PKIADASPDEGW-KRCNAAAQLVRKEFTVTSLDENQEYEFRV-------CAQNQVGIGRP 12091
Query: 253 HNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELH 312
K +P L P + V G + L V G P P+V W G + +
Sbjct: 12092 AELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-N 12150
Query: 313 NTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSD 370
Q+ + L+I + DD+G+Y+ NP+G V + SD
Sbjct: 12151 VVRKGQVDLVD-TMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12207
Score = 36.6 bits (83), Expect = 0.14
Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P + ++ K ++T V + G RLE V G
Sbjct: 17096 FRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGK 17155
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
P P I W + ++ + S + D L+++ A + D G Y + A N AG S
Sbjct: 17156 PLPTIEWLRGDKEIEESARCEIKNTDFKA--LLIVKDAIRIDGGQYILRASNVAGSKSFP 17213
Query: 1097 ARLDV 1101
+ V
Sbjct: 17214 VNVKV 17218
Score = 36.6 bits (83), Expect = 0.14
Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
G+ V L ++G P P + W+ + KEL + + DL +++I +A ++G Y
Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVE-NTTDLASILIKDADRLNSGCYEL 20448
Query: 345 LATNPSGSDTTSAEVFI 361
N GS + + V I
Sbjct: 20449 KLRNAMGSASATIRVQI 20465
Score = 36.6 bits (83), Expect = 0.14
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 5/103 (4%)
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHK 958
DEN P F +F L ++ G+ R+ V G P P ++W DG + +
Sbjct: 21454 DENVPPIVEFGPEYF----DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIE-KRMNM 21508
Query: 959 MLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+ G SL + T G+YT A N +G +++ V
Sbjct: 21509 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKV 21551
Score = 36.6 bits (83), Expect = 0.14
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC-LLIQGATKEDA 1079
V G PV L + G PPP W L S +RV++ + H + L I+ T D
Sbjct: 23253 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRES-ERVTV--ETHTKVAKLTIRETTIRDT 23309
Query: 1080 GWYTVSAKNEAGIVSCTARL 1099
G YT+ KN G S T ++
Sbjct: 23310 GEYTLELKNVTGTTSETIKV 23329
Score = 36.6 bits (83), Expect = 0.14
Identities = 20/97 (20%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V++G + R+ + G P P W +G+ + S M+ L+I+ D+G
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDI---SKRAMIATSETHTELVIKEADRGDSGT 23707
Query: 982 YTCIATNRAGQNSFSLEL-VVAAKEAHKPPVFIEKLQ 1017
Y + N+ G+ + +++ V+ + + + P+ + +Q
Sbjct: 23708 YDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQ 23744
Score = 36.2 bits (82), Expect = 0.18
Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 6/80 (7%)
Query: 284 EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC-EGGDLHTLIIAEA-FEDDTGR 341
EG V+L +T V W+ E K + + D + C + + +TL+I + ED G
Sbjct: 4256 EGDIVHLTTSITN--AKEVNWYFENKLVPS--DEKFKCLQDQNTYTLVIDKVNTEDHQGE 4311
Query: 342 YTCLATNPSGSDTTSAEVFI 361
Y C A N SG TSA++ +
Sbjct: 4312 YVCEALNDSGKTATSAKLTV 4331
Score = 36.2 bits (82), Expect = 0.18
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 1/86 (1%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
++ L V G+++ L VTG P P++ W L I I T+ I +
Sbjct: 7197 VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVD 7255
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAEV 359
+ DTG Y A N G T EV
Sbjct: 7256 SKRSDTGTYIIEAVNVCGRATAVVEV 7281
Score = 36.2 bits (82), Expect = 0.18
Identities = 39/169 (23%), Positives = 59/169 (34%), Gaps = 22/169 (13%)
Query: 824 YTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG 883
Y + + L GT + YT+ R +L V AVN G P +
Sbjct: 8539 YFVDKQLVGTNEWSRCTEKMIKVRQYTVKEI----REGADYKLRVSAVNAAGEGPPGETQ 8594
Query: 884 HPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLS 943
V P+ D + G + + GK R+ V+G P P
Sbjct: 8595 PVTVAEPQEPPAVELD--------------VSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8640
Query: 944 WQLDGKPVRPDSAHKMLVRENGVHS-LIIEPVTSRDAGIYTCIATNRAG 991
W + + D ++++ G S LII+ +D G Y ATN G
Sbjct: 8641 WTKEEGELDKD---RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8686
Score = 36.2 bits (82), Expect = 0.18
Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 9/123 (7%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKK 1045
A N AG + S + + P I+ + V +G V + ++ GVP P + W K
Sbjct: 9596 AVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFK 9655
Query: 1046 -------ENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTAR 1098
E + + T + D+ L+I + + D G YT++A N G S R
Sbjct: 9656 APPKKPDNKEPVLYDTHVNKLVVDDT--CTLVIPQSRRSDTGLYTITAVNNLGTASKEMR 9713
Query: 1099 LDV 1101
L+V
Sbjct: 9714 LNV 9716
Score = 36.2 bits (82), Expect = 0.18
Identities = 20/94 (21%), Positives = 36/94 (38%), Gaps = 1/94 (1%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P+ ++ + V G+ V + G P P +W +G E+ + +
Sbjct: 11011 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS-S 11069
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
L I DTG Y +N +GS T + + +
Sbjct: 11070 VLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 36.2 bits (82), Expect = 0.18
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G P ++ + G P P++ WK E E TDRVS+ L ++ + + D+G Y
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLE-EMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYF 22222
Query: 1084 VSAKNEAGI 1092
++ +N AG+
Sbjct: 22223 LTLENTAGV 22231
Score = 35.8 bits (81), Expect = 0.23
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
A F++ L Q V E C+++ V+W+ G+E+ + + G +H
Sbjct: 6324 APTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKKYKFE-KDGSIHR 6381
Query: 329 LIIAEAFEDDTGRYTC 344
LII + DD Y C
Sbjct: 6382 LIIKDCRLDDECEYAC 6397
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 11/127 (8%)
Query: 732 NQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEG 791
NQEY+ C Q + I E + + ++ ++ ++ M ++ G
Sbjct: 12073 NQEYEFRVCAQNQVG-IGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRA-------G 12124
Query: 792 MPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTI 851
P+ V G P PK+ W K G + + +D L ST DD G Y++
Sbjct: 12125 CPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL---VDTMAFLVIPNSTRDDSGKYSL 12181
Query: 852 MAANPQG 858
NP G
Sbjct: 12182 TLVNPAG 12188
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 12/109 (11%)
Query: 992 QNSFSLELVVAAKEAHKPPVFIEKLQN---------TGVADGYPVRLECRVLGVPPPQIF 1042
QN + KEA KP +E + V G P+RL V G P P++
Sbjct: 12083 QNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVT 12142
Query: 1043 WKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
W+K +V + D + L+I +T++D+G Y+++ N AG
Sbjct: 12143 WRKVGIDNVVRKGQVDL-VDTMAF--LVIPNSTRDDSGKYSLTLVNPAG 12188
Score = 35.8 bits (81), Expect = 0.23
Identities = 19/82 (23%), Positives = 35/82 (42%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ ++ + G P PD+ W DGK + +A + +L+++ D
Sbjct: 18220 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18279
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y +N G S + + V
Sbjct: 18280 GQYILKLSNVGGTKSIPITVKV 18301
Score = 35.8 bits (81), Expect = 0.23
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V+ G ++D +SG P P ++ DG P++ + + + E VT+ DAG
Sbjct: 19991 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTA-DAGR 20049
Query: 982 YTCIATNRAGQNSFSLELVV 1001
Y A N +G + +VV
Sbjct: 20050 YEITAANSSGTTKAFINIVV 20069
Score = 35.4 bits (80), Expect = 0.30
Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 986 ATNRAGQNSF---SLELVVAAKEAHKPPVFIEKLQNTGV---ADGYPVRLECRVLGVPPP 1039
A N AG S S E ++ E P + ++ G+ A V +LG P P
Sbjct: 13853 AKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLP 13912
Query: 1040 QIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
+ W K + + S ++ L I+ AT++DAG YT++A N G
Sbjct: 13913 KSSWSKAGKDIRPSD--ITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962
Score = 35.4 bits (80), Expect = 0.30
Identities = 24/60 (40%), Positives = 27/60 (45%), Gaps = 4/60 (6%)
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA-STLDDDGNYTIMAANPQG 858
+ G P PK W K GK I P Q T S+ T +T D G YTI A NP G
Sbjct: 13906 ILGKPLPKSSWSKAGKDIRPSD---ITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962
Score = 35.4 bits (80), Expect = 0.30
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V G ++ + G P P ++W +EL NT ++I + D T L + +A D+G
Sbjct: 16058 VHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEI--KSTDFATSLSVKDAVRVDSG 16115
Query: 341 RYTCLATNPSGSDTTSAEV 359
Y A N +G + + V
Sbjct: 16116 NYILKAKNVAGERSVTVNV 16134
Score = 35.4 bits (80), Expect = 0.30
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V G LE V G P P + W KE+ + +I + D LI+ +A D G
Sbjct: 17140 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI--KNTDFKALLIVKDAIRIDGG 17197
Query: 341 RYTCLATNPSGSDTTSAEV 359
+Y A+N +GS + V
Sbjct: 17198 QYILRASNVAGSKSFPVNV 17216
Score = 35.4 bits (80), Expect = 0.30
Identities = 20/85 (23%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+T + G +D +SG P P ++W+L+ ++ + ++ +L ++ D+
Sbjct: 22160 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRT-TLTVKDSMRGDS 22218
Query: 980 GIYTCIATNRAGQNSFSLELVVAAK 1004
G Y N AG +FS+ +VV +
Sbjct: 22219 GRYFLTLENTAGVKTFSVTVVVIGR 22243
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V EG ++ + P P V W +GKE+ + + + + H L + ++ D G
Sbjct: 7901 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH-LEVPKSVRADAGI 7959
Query: 342 YTCLATNPSGSDTTSAEVFIEG 363
YT N GS T S V + G
Sbjct: 7960 YTITLENKLGSATASINVKVIG 7981
Score = 35.0 bits (79), Expect = 0.39
Identities = 25/94 (26%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS-LIIEPVTSRDAG 980
++ G R+ + G+P P ++W+ + + D+ K + V S L I D G
Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDR----DAPTKARIDVTPVGSKLEIRNAAHEDGG 10788
Query: 981 IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIE 1014
IY+ N AG + S++++V K PP +E
Sbjct: 10789 IYSLTVENPAGSKTVSVKVLVLDKPG--PPRDLE 10820
Score = 35.0 bits (79), Expect = 0.39
Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 17/80 (21%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH--------SLII 971
+TV+ G+ R+ +V G P PD++W +G K+LVRE V L I
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEG---------KVLVREKRVDLIQDLPRVELQI 11471
Query: 972 EPVTSRDAGIYTCIATNRAG 991
+ D G Y A N +G
Sbjct: 11472 KEAVRADHGKYIISAKNSSG 11491
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F + V G + ++ G PTP V W + L T +++ E + ++L+
Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQT--TRVNAESTENNSLL 15708
Query: 331 -IAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
I +A +D G Y TN +G + V +
Sbjct: 15709 TIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15740
Score = 35.0 bits (79), Expect = 0.39
Identities = 21/71 (29%), Positives = 29/71 (40%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G LE + G P P V W +GKEL T TL++ + D G+
Sbjct: 18222 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281
Query: 342 YTCLATNPSGS 352
Y +N G+
Sbjct: 18282 YILKLSNVGGT 18292
Score = 35.0 bits (79), Expect = 0.39
Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 4/118 (3%)
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGVPPPQIFW 1043
A + + S S ++ + P V ++ K ++ V G +++ + G P P I W
Sbjct: 19267 AADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISW 19326
Query: 1044 KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
K+ + + DNH L ++ + D G Y ++ KN AG S V
Sbjct: 19327 AKDGIEIEERARTEIISTDNH--TLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19382
Score = 35.0 bits (79), Expect = 0.39
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTG 340
V +G + L + G P P +W EG+++ I + HT L+I EA D+G
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIAT----SETHTELVIKEADRGDSG 23706
Query: 341 RYTCLATNPSGSDTTSAEVFIEGASST 367
Y + N G +V + G+ ++
Sbjct: 23707 TYDLVLENKCGKKAVYIKVRVIGSPNS 23733
Score = 34.7 bits (78), Expect = 0.51
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 10/94 (10%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTL-DDDGNY 849
G V F + G P P W DG +I +HYT+ + D S+ T + L D G Y
Sbjct: 11028 GTTVRFPAIIRGVPVPTAKWTTDGSEIK-TDEHYTV--ETDNFSSVLTIKNCLRRDTGEY 11084
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSG 883
I +N G + L V V P P+G
Sbjct: 11085 QITVSNAAGSKTVAVHLTVLDV------PGPPTG 11112
Score = 34.7 bits (78), Expect = 0.51
Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 1/78 (1%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G + + RV G P P + W EGK L + + + L I EA D G+
Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL-IQDLPRVELQIKEAVRADHGK 11481
Query: 342 YTCLATNPSGSDTTSAEV 359
Y A N SG SA V
Sbjct: 11482 YIISAKNSSGHAQGSAIV 11499
Score = 34.7 bits (78), Expect = 0.51
Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G + RV G P+P I W K+GK + + + +DL L + D G Y
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKEGK-VLVREKRVDLIQDLP-RVELQIKEAVRADHGKYI 11483
Query: 851 IMAANPQGRISCTGRLMVQAVNQRG 875
I A N G G +V +++ G
Sbjct: 11484 ISAKNSSGH--AQGSAIVNVLDRPG 11506
Score = 34.7 bits (78), Expect = 0.51
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Query: 294 VTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSD 353
+ G P P+ W GK++ + QI L I A D G YT ATNP G+
Sbjct: 13906 ILGKPLPKSSWSKAGKDIRPSDITQITSTPTS-SMLTIKYATRKDAGEYTITATNPFGTK 13964
Query: 354 TTSAEVFI 361
+V +
Sbjct: 13965 VEHVKVTV 13972
Score = 34.7 bits (78), Expect = 0.51
Identities = 27/101 (26%), Positives = 52/101 (51%), Gaps = 7/101 (6%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSW-QLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
+ ++ G R+ + G PTP++ W ++DG+ +R D+A ++ + SL+++ V D
Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGE-IR-DAA--IIDVTSSFTSLVLDNVNRYD 16510
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT 1019
+G YT N +G S + V + PPV ++ + T
Sbjct: 16511 SGKYTLTLENSSGTK--SAFVTVRVLDTPSPPVNLKVTEIT 16549
Score = 34.7 bits (78), Expect = 0.51
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 917 PG-DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
PG +TV+ G ++ G P P +SW DG P++ + EN + +L I+
Sbjct: 21072 PGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAK 21130
Query: 976 SRDAGIYTCIATN 988
G YT I N
Sbjct: 21131 KEHGGKYTVILDN 21143
Score = 34.3 bits (77), Expect = 0.67
Identities = 26/129 (20%), Positives = 55/129 (42%), Gaps = 7/129 (5%)
Query: 966 VHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF---IEKLQNTGVA 1022
+ ++ + +++ + A N AG ++ V E P F E + V
Sbjct: 14233 ITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVR 14292
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
G +R+ + G P P++ W K+N +L + + ++ + L+I + D G +
Sbjct: 14293 AGLSIRIFVPIKGRPAPEVTWTKDNINLKNRAN----IENTESFTLLIIPECNRYDTGKF 14348
Query: 1083 TVSAKNEAG 1091
++ +N AG
Sbjct: 14349 VMTIENPAG 14357
Score = 33.9 bits (76), Expect = 0.88
Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 3/92 (3%)
Query: 272 RFIQKLRSQ-EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
RF++ L + V +G +YL C + N V W +GK + P + G + L
Sbjct: 4716 RFVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALT 4773
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
I +A + D G YT N + + +S +E
Sbjct: 4774 INDADDTDAGTYTVTVENANNLECSSCVKVVE 4805
Score = 33.9 bits (76), Expect = 0.88
Identities = 28/165 (16%), Positives = 63/165 (38%), Gaps = 15/165 (9%)
Query: 942 LSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN--SFSLEL 999
+++ L+ + + + HK+ ++ + D Y A N GQ SF +
Sbjct: 10252 INYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP 10311
Query: 1000 VVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESL--------- 1050
+ E P + ++ + G L R G P P++ W K+ +
Sbjct: 10312 ITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIK 10371
Query: 1051 ----THSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
T + +++ + + G C++++ +T G+ V+ + G
Sbjct: 10372 TTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG 10416
Score = 33.9 bits (76), Expect = 0.88
Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS-LIIE 972
L+ G LTV+ G R++ V G P P+++W D + ++ + S +
Sbjct: 11708 LKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT 11767
Query: 973 PVTSRDAGIYTCIATNRAG 991
D G Y ATN AG
Sbjct: 11768 KAKRSDGGKYVVTATNTAG 11786
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 3/74 (4%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFED 337
R+ V G + + + G P P V W + L N +I+ + E L LII E
Sbjct: 14287 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE-NTESFTL--LIIPECNRY 14343
Query: 338 DTGRYTCLATNPSG 351
DTG++ NP+G
Sbjct: 14344 DTGKFVMTIENPAG 14357
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 1027 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 1086
+RL + G P P++ W+K L TDR + + + L+I T+ D+G Y ++
Sbjct: 18628 LRLFVTIKGRPEPEVKWEKAEGIL---TDRAQI-EVTSSFTMLVIDNVTRFDSGRYNLTL 18683
Query: 1087 KNEAGIVSCTARLDVYI 1103
+N +G S TA ++V +
Sbjct: 18684 ENNSG--SKTAFVNVRV 18698
Score = 33.9 bits (76), Expect = 0.88
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V GS + ++ ++G P P+V +G L T +L T+ + E+ D GR
Sbjct: 19991 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL-TINLKESVTADAGR 20049
Query: 342 YTCLATNPSGSDTTSAEVFI 361
Y A N SG TT A + I
Sbjct: 20050 YEITAANSSG--TTKAFINI 20067
Score = 33.9 bits (76), Expect = 0.88
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 777 PFFEMKLKHYKIFE---GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT 833
P ++ L++ ++ + G V ++G P P I W+KD K++ + ++ D
Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA-LVCVENTTDLA 20431
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
L A L + G Y + N G S T R+ +
Sbjct: 20432 SILIKDADRL-NSGCYELKLRNAMGSASATIRVQI 20465
Score = 33.9 bits (76), Expect = 0.88
Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 6/110 (5%)
Query: 986 ATNRAGQNS-FSLELVVAAKEA-HKPPVFIEKLQNTGVAD--GYPVRLECRVLGVPPPQI 1041
A N AGQ + V AK+ P + ++ T V G V++ G PPP +
Sbjct: 20747 AVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTV 20806
Query: 1042 FWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
W+K+ ++L S R S+ + + L I T+ D G Y ++ +N G
Sbjct: 20807 TWRKDEKNL-GSDARYSIENTDSSSL-LTIPQVTRNDTGKYILTIENGVG 20854
Score = 33.9 bits (76), Expect = 0.88
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 8/87 (9%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
+ G+ + ++ V+G P +V WF+ G EI+ + I + +L + +
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST--------SLFVRDA 21524
Query: 512 FPEDAGIFTCSARNDYGSATSTAQLVV 538
+ G++T A+N GSA + ++ V
Sbjct: 21525 TRDHRGVYTVEAKNASGSAKAEIKVKV 21551
Score = 33.5 bits (75), Expect = 1.1
Identities = 31/124 (25%), Positives = 49/124 (39%), Gaps = 6/124 (4%)
Query: 982 YTCIATNRAGQNSFS--LELVVAAKEAHKPPVFIEK--LQNTGVADGYPVRLECRVLGVP 1037
Y A NR G + S E + A P +F++ L V G + L V G P
Sbjct: 7162 YRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 7221
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 1097
P+I W K + L D+ ++ + I + + D G Y + A N G +
Sbjct: 7222 EPKITWTKADMIL--KQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVV 7279
Query: 1098 RLDV 1101
++V
Sbjct: 7280 EVNV 7283
Score = 33.5 bits (75), Expect = 1.1
Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 6/84 (7%)
Query: 914 LQAPGD-LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS---- 968
L GD + V+ G+ + V+GLP P + W + + + + +E S
Sbjct: 8904 LSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKT 8963
Query: 969 -LIIEPVTSRDAGIYTCIATNRAG 991
L I D G YT A+NR G
Sbjct: 8964 ELSIPKAVREDKGTYTVTASNRLG 8987
Score = 33.5 bits (75), Expect = 1.1
Identities = 17/73 (23%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G + R+ VSG P P ++W ++ + + ++ + + S++I+
Sbjct: 10037 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS---SMVIKNCQRSHQ 10093
Query: 980 GIYTCIATNRAGQ 992
G+Y+ +A N AG+
Sbjct: 10094 GVYSLLAKNEAGE 10106
Score = 33.5 bits (75), Expect = 1.1
Identities = 49/202 (24%), Positives = 82/202 (40%), Gaps = 21/202 (10%)
Query: 901 NEPIQERFFRPHFLQAPG-DLTV--------QEGKLCRMDCKVSGLPTPDLSWQLDGKPV 951
NEP+Q + L+AP DL V + G+ ++ G P P ++W+ D K +
Sbjct: 20760 NEPVQAK----DILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNL 20815
Query: 952 RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPV 1011
D+ + + + L I VT D G Y N G+ S + + P
Sbjct: 20816 GSDARYS-IENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSS----TVSVKVLDTPA 20870
Query: 1012 FIEKLQNTGVADGYPVRL-ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
+KLQ V+ G L + ++ P I + E T T V H+ + L+
Sbjct: 20871 ACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLI 20930
Query: 1071 IQGATKEDAGWYTVSAKNEAGI 1092
+++ ++ V A+NE GI
Sbjct: 20931 --DLSEKTPFFFRVLAENEIGI 20950
Score = 33.5 bits (75), Expect = 1.1
Identities = 33/137 (24%), Positives = 61/137 (44%), Gaps = 8/137 (5%)
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELV--VAAKEAHKPPVFIEKLQNTG----VADG 1024
+ ++ D + +A N AG S E V ++ + PP + G + G
Sbjct: 22506 VTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAG 22565
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
+ L+ V G P P+I W K ++ L ++VS+ Q +I+ + D+G YT+
Sbjct: 22566 SDLVLDAAVGGKPEPKIIWTKGDKEL-DLCEKVSL-QYTGKRATAVIKFCDRSDSGKYTL 22623
Query: 1085 SAKNEAGIVSCTARLDV 1101
+ KN +G + + + V
Sbjct: 22624 TVKNASGTKAVSVMVKV 22640
Score = 33.1 bits (74), Expect = 1.5
Identities = 31/130 (23%), Positives = 53/130 (40%), Gaps = 18/130 (13%)
Query: 986 ATNRAGQN--SFSLELVVAAKEAHKPPVFIEKLQNTGVAD------GYPVRLECRVLGVP 1037
A N AG++ S + + A +P VFI+ G D G +R+ + G P
Sbjct: 9286 AVNEAGESEPSDTTGEIPATDIQEEPEVFID----IGAQDCLVCKAGSQIRIPAVIKGRP 9341
Query: 1038 PPQIFW------KKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
P+ W KK + H + + ++I + G Y+++AKN+AG
Sbjct: 9342 TPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAG 9401
Query: 1092 IVSCTARLDV 1101
+ R+ V
Sbjct: 9402 QKTANCRVKV 9411
Score = 33.1 bits (74), Expect = 1.5
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 12/82 (14%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESL----THSTDRVSMHQDNHGYICLLIQGATKEDA 1079
G +R+ V G PPP + W +L T T +S ++I+ +
Sbjct: 10042 GGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSS--------MVIKNCQRSHQ 10093
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G Y++ AKNEAG T +DV
Sbjct: 10094 GVYSLLAKNEAGERKKTIIVDV 10115
Score = 33.1 bits (74), Expect = 1.5
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 284 EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-LIIAEAFEDDTGRY 342
E S L+ + G P P V W +G++ T D ++ E ++T LI+ + + D G+Y
Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWK-KGEDPLAT-DTRVSVESSAVNTTLIVYDCQKSDAGKY 13556
Query: 343 TCLATNPSGSDTTSAEVFIEG 363
T N +G+ + + + G
Sbjct: 13557 TITLKNVAGTKEGTISIKVVG 13577
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
+V GQ + +E + G P + W + G ++ + + + ++ TL I E
Sbjct: 16743 SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINV--------TDSLDLTTLSIKE 16794
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLV 537
T +D G + + N G T++ ++V
Sbjct: 16795 THKDDGGQYGITVANVVGQKTASIEIV 16821
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
V G R+ G P P+I W +E TD+V + + Y L I + DAG
Sbjct: 17539 VRAGGSARIHIPFKGRPTPEITWSREEGEF---TDKVQI-EKGVNYTQLSIDNCDRNDAG 17594
Query: 1081 WYTVSAKNEAGIVSCTARLDV 1101
Y + +N +G S + V
Sbjct: 17595 KYILKLENSSGSKSAFVTVKV 17615
Score = 33.1 bits (74), Expect = 1.5
Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 296 GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTT 355
G P V W +G+ L T + + + +L I EA ++D G Y +N +GS T
Sbjct: 18923 GRPQATVNWRKDGQTLKETTRVNVS-SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 18981
Query: 356 SAEVFI 361
+ +
Sbjct: 18982 PITIIV 18987
Score = 32.7 bits (73), Expect = 2.0
Identities = 66/322 (20%), Positives = 121/322 (37%), Gaps = 62/322 (19%)
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
+A F K ++ +I EG F C ++ P + W +D K + D Y + D
Sbjct: 6053 LAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLE-SGDKYDVIADGKKRV 6110
Query: 835 SLHTTASTLDDDGNYTIM--AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRS 892
L +TL D G Y +M AA ++ +L +
Sbjct: 6111 -LVVKDATLQDMGTYVVMVGAARAAAHLTVIEKLRIVV---------------------- 6147
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
P++ D V+E + +C+V+ W + + +
Sbjct: 6148 ----------PLK-------------DTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIF 6183
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF 1012
DS+ ++++++ V++L I D Y TN G+N S ++ +E +
Sbjct: 6184 -DSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLR---I 6239
Query: 1013 IEKLQNTGVADGYPVRLECRV--LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLL 1070
+E L++ + V C+V L V + W K E + +RVS D + ++ L
Sbjct: 6240 VEPLKDIETMEKKSVTFWCKVNRLNV---TLKWTKNGEEVPFD-NRVSYRVDKYKHM-LT 6294
Query: 1071 IQGATKEDAGWYTVSAKNEAGI 1092
I+ D G Y V+A + +
Sbjct: 6295 IKDCGFPDEGEYIVTAGQDKSV 6316
Score = 32.7 bits (73), Expect = 2.0
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD-IQIHCE---GGDLHT-LIIAEAF 335
+V G V++ VTG P P++ W + D +QI E + T L I +A
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971
Query: 336 EDDTGRYTCLATNPSGS 352
+D G YT A+N GS
Sbjct: 8972 REDKGTYTVTASNRLGS 8988
Score = 32.7 bits (73), Expect = 2.0
Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 920 LTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDA 979
+ V G+ ++D + G P P + W + G ++A + + SL ++ D+
Sbjct: 16056 IVVHAGESFKVDADIYGKPIPTIQW-IKGDQELSNTARLEIKSTDFATSLSVKDAVRVDS 16114
Query: 980 GIYTCIATNRAGQNSFSLELVV 1001
G Y A N AG+ S ++ + V
Sbjct: 16115 GNYILKAKNVAGERSVTVNVKV 16136
Score = 32.7 bits (73), Expect = 2.0
Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G+ V LE G P P I W K+ L S I L I+ A KE G YT
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKES--EFVRFSKTENKITLSIKNAKKEHGGKYT 21138
Query: 1084 VSAKN 1088
V N
Sbjct: 21139 VILDN 21143
Score = 32.3 bits (72), Expect = 2.5
Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 271 PRFIQKLRSQEVA---EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
PR + ++ ++V G + + + G P P + W +G E+ +I D H
Sbjct: 19290 PRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI--ISTDNH 19347
Query: 328 TLI-IAEAFEDDTGRYTCLATNPSGS 352
TL+ + + DTG+Y N +G+
Sbjct: 19348 TLLTVKDCIRRDTGQYVLTLKNVAGT 19373
Score = 32.3 bits (72), Expect = 2.5
Identities = 22/105 (20%), Positives = 47/105 (44%), Gaps = 11/105 (10%)
Query: 437 AYFPPVFTKELQNTAVAE---GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKK 493
+Y PV L+ T V + G V L + G P ++W++ E+Q + +
Sbjct: 20369 SYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCV---- 20424
Query: 494 PRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ +++I + ++G + RN GSA++T ++ +
Sbjct: 20425 ----ENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 20465
Score = 32.3 bits (72), Expect = 2.5
Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 918 GDL-TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTS 976
GDL T++ G +D V G P P + W K + D K+ ++ G + +
Sbjct: 22557 GDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCD 22614
Query: 977 R-DAGIYTCIATNRAGQNSFSLELVV 1001
R D+G YT N +G + S+ + V
Sbjct: 22615 RSDSGKYTLTVKNASGTKAVSVMVKV 22640
Score = 32.0 bits (71), Expect = 3.3
Identities = 49/236 (20%), Positives = 90/236 (38%), Gaps = 26/236 (11%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+ I+ LR E V E ++ + V W + KE+ + +I G ++ L +
Sbjct: 2488 KIIRGLRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHG-KIYKLTV 2545
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGAS-------STDSDSESLAFKSRAGAMP 384
+DD G+YT A G + TS ++ + G + T ++S+ F+ A P
Sbjct: 2546 LNMMKDDEGKYTFYA----GENMTSGKLTVAGGAISKPLTDQTVAESQEAVFECEV-ANP 2600
Query: 385 QAQ----KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFP 440
++ + + LT S G +I + ++ Y + + T+
Sbjct: 2601 DSKGEWLRDGKHLPLTNNIRSESDGHKRRLI----IAATKLDDIGEYTYKVATSKTSAKL 2656
Query: 441 PV----FTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
V K L+N V E Q V + VQW + G ++ + + I K
Sbjct: 2657 KVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVK 2712
Score = 32.0 bits (71), Expect = 3.3
Identities = 21/78 (26%), Positives = 32/78 (41%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G + L + G PTP V+W GK D I +L++ D+G+
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKW---GKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGK 16513
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SG+ + V
Sbjct: 16514 YTLTLENSSGTKSAFVTV 16531
Score = 32.0 bits (71), Expect = 3.3
Identities = 30/118 (25%), Positives = 44/118 (37%), Gaps = 6/118 (5%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
+P L P + + V G + G PTP + W E E T +QI
Sbjct: 17517 KPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQI 17574
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFK 377
+G + L I +D G+Y N SGS + V + T ++LA K
Sbjct: 17575 E-KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV---LDTPGPPQNLAVK 17628
Score = 32.0 bits (71), Expect = 3.3
Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 982 YTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIE-KLQNTGVAD-GYPVRLECRVLGV 1036
+ IA N AG + S S + A E P ++ K ++ V G LE + G
Sbjct: 18178 FRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGK 18237
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 1094
P P + W K+ + L + R+ + + L+++ + D G Y + N G S
Sbjct: 18238 PIPDVVWSKDGKELEETAARMEI-KSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18294
Score = 31.6 bits (70), Expect = 4.3
Identities = 20/88 (22%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
++ G+ + +E V G P + W + G ++ + + E L I E
Sbjct: 17825 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV--------EETATSTVLHIKE 17876
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVV 538
+D G +T +A N G+AT ++V
Sbjct: 17877 GNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 31.6 bits (70), Expect = 4.3
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
G V+LE G P P + W +G L + ++ + TL I A ++ G+YT
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAKKEHGGKYTV 21139
Query: 345 LATN 348
+ N
Sbjct: 21140 ILDN 21143
Score = 31.6 bits (70), Expect = 4.3
Identities = 22/80 (27%), Positives = 31/80 (38%), Gaps = 3/80 (3%)
Query: 922 VQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGI 981
V+ G R+ G PTP W KP S + + +L +E DAG
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWS---KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGK 21928
Query: 982 YTCIATNRAGQNSFSLELVV 1001
YT N +G S + + V
Sbjct: 21929 YTLTVENNSGSKSITFTVKV 21948
Score = 31.6 bits (70), Expect = 4.3
Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G+ + L G PTP W L DI TL + +D G+
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTT---DSFSTLTVENCNRNDAGK 21928
Query: 342 YTCLATNPSGSDTTSAEV 359
YT N SGS + + V
Sbjct: 21929 YTLTVENNSGSKSITFTV 21946
Score = 31.6 bits (70), Expect = 4.3
Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 9/112 (8%)
Query: 770 PVENGMAPFFEMK---LKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTI 826
PVE P E+ K I G + V+G P P I W K G ++ ++ I
Sbjct: 22940 PVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRA----I 22995
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
+ L D G YTI A N G+ S T ++V+ + G P
Sbjct: 22996 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSAT--VLVKVYDTPGPCP 23045
Score = 31.6 bits (70), Expect = 4.3
Identities = 21/94 (22%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 446 ELQNTAVAEGQVVVLECRVRGAPP-LQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
++ + EG V C++ QV W+ ++++S + I + + +
Sbjct: 25076 QIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE--------DGVA 25127
Query: 505 TLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
L + + D G + C NDYG +S A+L V
Sbjct: 25128 ILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25161
Score = 31.2 bits (69), Expect = 5.7
Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
A FI K ++ E+ EG + C ++ P V+W + K L + + + G L
Sbjct: 6054 AAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIAD-GKKRVL 6111
Query: 330 IIAEAFEDDTGRYTCL 345
++ +A D G Y +
Sbjct: 6112 VVKDATLQDMGTYVVM 6127
Score = 31.2 bits (69), Expect = 5.7
Identities = 18/69 (26%), Positives = 29/69 (42%), Gaps = 5/69 (7%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P+T PK + WFK+ + +S K+ T ++ S + D G Y
Sbjct: 6517 GKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQ-----TSFRILEAKKGDKGRYK 6571
Query: 851 IMAANPQGR 859
I+ N G+
Sbjct: 6572 IVLQNKHGK 6580
Score = 31.2 bits (69), Expect = 5.7
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 7/78 (8%)
Query: 452 VAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAET 511
V G+ VLE +RG P V W + G E++++ + + +ST + TLV+ +
Sbjct: 18222 VHAGETFVLEADIRGKPIPDVVWSKDGKELEET----AARMEIKSTIQK---TTLVVKDC 18274
Query: 512 FPEDAGIFTCSARNDYGS 529
D G + N G+
Sbjct: 18275 IRTDGGQYILKLSNVGGT 18292
Score = 31.2 bits (69), Expect = 5.7
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
+ G+ + L V+G P P + W +G +L + I E L LI+ + D G+
Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDT-TESYSL--LIVDKVNRYDAGK 23017
Query: 342 YTCLATNPSGSDTTSAEV 359
YT A N SG + + V
Sbjct: 23018 YTIEAENQSGKKSATVLV 23035
Score = 31.2 bits (69), Expect = 5.7
Identities = 30/114 (26%), Positives = 48/114 (42%), Gaps = 7/114 (6%)
Query: 254 NRKSHPQPHSALHFPAAPRFIQKLRSQEV---AEGSRVYLECRVTGNPTPRVRWFCEGKE 310
N + S L A P+F +E A GS + L G P P + WF K
Sbjct: 24112 NEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKL 24171
Query: 311 LHNTPDIQIHCEGGDLHTLIIAEAFEDDT--GRYTCLATNPSGSDTTSAEVFIE 362
L N+ +I I E + +T ++ + + T G+Y +N G+ +V I+
Sbjct: 24172 LQNSENITI--ENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24223
Score = 30.8 bits (68), Expect = 7.4
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 9/85 (10%)
Query: 433 GTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
G + Y V T L++ V EG VLEC+V V+W+ +I+ PD R+ Q
Sbjct: 2392 GRVSVYSVDVITP-LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIK--PDDRV-QA 2447
Query: 493 KPRSTAEPEEICTLVIAETFPEDAG 517
+ T + LVI T D G
Sbjct: 2448 IVKGTKQ-----RLVINRTHASDEG 2467
Score = 30.8 bits (68), Expect = 7.4
Identities = 24/95 (25%), Positives = 34/95 (35%), Gaps = 10/95 (10%)
Query: 445 KELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
K ++ V G V +RG P +W GSEI+ + T E +
Sbjct: 11018 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHY---------TVETDNFS 11068
Query: 505 T-LVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ L I D G + + N GS T L V
Sbjct: 11069 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 30.8 bits (68), Expect = 7.4
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 8/76 (10%)
Query: 455 GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPE 514
G+ LE V G PP ++W + G E++ + I + LV ++
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEI--------KIADFSTNLVNKDSTRR 15030
Query: 515 DAGIFTCSARNDYGSA 530
D+G +T +A N G A
Sbjct: 15031 DSGAYTLTATNPGGFA 15046
Score = 30.8 bits (68), Expect = 7.4
Identities = 26/98 (26%), Positives = 39/98 (39%), Gaps = 9/98 (9%)
Query: 1003 AKEAHKPPVF---IEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSM 1059
AKE + P+F E + V G + G P P + W K + L R
Sbjct: 19680 AKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-----RTRA 19734
Query: 1060 HQDN-HGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
+ D L I+ A + D+G YT++ +N S T
Sbjct: 19735 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT 19772
Score = 30.4 bits (67), Expect = 9.7
Identities = 20/94 (21%), Positives = 40/94 (42%), Gaps = 8/94 (8%)
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
+ + G+ + +E V G P +W + E+ S + + S L+
Sbjct: 12409 EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI--------LI 12460
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA 541
I + +D+G ++ +A N G+ T ++VV A
Sbjct: 12461 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 12494
Score = 30.4 bits (67), Expect = 9.7
Identities = 26/119 (21%), Positives = 50/119 (42%), Gaps = 10/119 (8%)
Query: 749 EYRLERSPVDESG--DEVQYGDVP-VENGMAPFFEMKLKHYK---IFEGMPVTFTCRVAG 802
+Y S ++++G + DV VE MAP FE+ + + + G+ + + G
Sbjct: 14246 KYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKG 14305
Query: 803 NPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 861
P P++ W KD + +++ + + L D G + + NP G+ S
Sbjct: 14306 RPAPEVTWTKDNINLKNRAN----IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKS 14360
Score = 30.4 bits (67), Expect = 9.7
Identities = 17/60 (28%), Positives = 26/60 (43%), Gaps = 2/60 (3%)
Query: 802 GNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRIS 861
G PKP I W KDG + K + + +L + + G YT++ N RI+
Sbjct: 21092 GKPKPSISWLKDGLPL--KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIA 21149
Score = 30.4 bits (67), Expect = 9.7
Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P T ++G P PK+ W + ++ ++D +I D T +L S D G Y
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLK-ETDRVSITTTKDRT-TLTVKDSMRGDSGRYF 22222
Query: 851 IMAANPQG 858
+ N G
Sbjct: 22223 LTLENTAG 22230
>gi|209693444 myotilin isoform b [Homo sapiens]
Length = 314
Score = 243 bits (620), Expect = 7e-64
Identities = 110/213 (51%), Positives = 155/213 (72%)
Query: 889 RPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDG 948
R RS SR ++ + IQE+F+ P F+Q P ++++ EG+ CRMD KVSGLP PD+SW L+G
Sbjct: 44 RSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 103
Query: 949 KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK 1008
+ V+ D HKM+V E G+HSLI E V + DAG Y C+A NRAG+ +F+++L V AKE +
Sbjct: 104 RTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR 163
Query: 1009 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
P+FI K Q+ V +G V+LEC++ +PPP++FWK+ NE + +TDR+S++QDN G +
Sbjct: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
LLI+ K+DAGWYTVSA NEAG+ +C RLDV
Sbjct: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
Score = 78.6 bits (192), Expect = 3e-14
Identities = 80/299 (26%), Positives = 125/299 (41%), Gaps = 42/299 (14%)
Query: 708 MARRLLGA-DSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQY 766
MARRLLG ++A VF Q+ +Q++ +S RL ++ RS GD V
Sbjct: 1 MARRLLGPQNAAAVFQAQDDSGAQDSQQH--NSEHARL--QVPTSQVRSRSTSRGD-VND 55
Query: 767 GDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTI 826
D E P F ++ I EG +V+G P P + W+ +G+ + H I
Sbjct: 56 QDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 115
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH 886
+ G SL D G Y +A N G + T +L V A
Sbjct: 116 VSE-KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA---------------- 158
Query: 887 VRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL 946
+E P F+ P V EG +++C++S +P P L W+
Sbjct: 159 ------------------KEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKR 200
Query: 947 DGKPVRPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
+ + V+ ++ L ++N G +L+I+ V +DAG YT A N AG + + L V A+
Sbjct: 201 NNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
Score = 60.8 bits (146), Expect = 7e-09
Identities = 62/270 (22%), Positives = 105/270 (38%), Gaps = 77/270 (28%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
PRFIQ + + EG ++ +V+G P P V W+ G+ + + DLH +I
Sbjct: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTV----------QSDDLHKMI 115
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
++E G ++ + E ++D+ + + K+RAG + T
Sbjct: 116 VSEK-----GLHSLI---------------FEVVRASDAGAYACVAKNRAG------EAT 149
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT 450
+V L + + K P+F + Q+
Sbjct: 150 FTVQLDVLAKEHKRA-----------------------------------PMFIYKPQSK 174
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
V EG V LEC++ PP ++ W R +Q + D L + TL+I +
Sbjct: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV------TLLIKD 228
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
+DAG +T SA N+ G T +L VT+
Sbjct: 229 VNKKDAGWYTVSAVNEAGVTTCNTRLDVTA 258
Score = 57.0 bits (136), Expect = 1e-07
Identities = 47/194 (24%), Positives = 81/194 (41%), Gaps = 24/194 (12%)
Query: 414 LSVPVQQVHSPTSY---LCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPL 470
L VP QV S ++ + D ++PP F + +N ++ EG+ ++ +V G P
Sbjct: 36 LQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAP 95
Query: 471 QVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSA 530
V W+ G +Q +++ + + +L+ DAG + C A+N G A
Sbjct: 96 DVSWYLNGRTVQSDDLHKMI-------VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEA 148
Query: 531 TSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNP 590
T T QL V + + F + P +LE S++L +I + P
Sbjct: 149 TFTVQLDVLAKEHKRAPM----------FIYKPQSKKVLEGDSVKL----ECQISAIPPP 194
Query: 591 ELGLSRAALQMQFN 604
+L R +QFN
Sbjct: 195 KLFWKRNNEMVQFN 208
Score = 55.5 bits (132), Expect = 3e-07
Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 1/105 (0%)
Query: 1002 AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQ 1061
A +E PP FI+ +N + +G R++ +V G+P P + W ++ S D M
Sbjct: 58 AIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTV-QSDDLHKMIV 116
Query: 1062 DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISRH 1106
G L+ + DAG Y AKN AG + T +LDV H
Sbjct: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEH 161
Score = 53.1 bits (126), Expect = 1e-06
Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELH-NTPDIQIHCEGGDLHT 328
AP FI K +S++V EG V LEC+++ P P++ W + + NT I ++ + T
Sbjct: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEV 359
L+I + + D G YT A N +G T + +
Sbjct: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
>gi|5803106 myotilin isoform a [Homo sapiens]
Length = 498
Score = 243 bits (620), Expect = 7e-64
Identities = 110/213 (51%), Positives = 155/213 (72%)
Query: 889 RPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDG 948
R RS SR ++ + IQE+F+ P F+Q P ++++ EG+ CRMD KVSGLP PD+SW L+G
Sbjct: 228 RSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 287
Query: 949 KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK 1008
+ V+ D HKM+V E G+HSLI E V + DAG Y C+A NRAG+ +F+++L V AKE +
Sbjct: 288 RTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR 347
Query: 1009 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
P+FI K Q+ V +G V+LEC++ +PPP++FWK+ NE + +TDR+S++QDN G +
Sbjct: 348 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 407
Query: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
LLI+ K+DAGWYTVSA NEAG+ +C RLDV
Sbjct: 408 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 440
Score = 132 bits (332), Expect = 2e-30
Identities = 136/474 (28%), Positives = 203/474 (42%), Gaps = 64/474 (13%)
Query: 553 ESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVN---------NPELGLSRAALQMQF 603
+S N PP P ETSS +K+ S I Q + L F
Sbjct: 12 QSQNPCGSRLQPPGP--ETSSFSSQTKQSSIIIQPRQCTEQRFSASSTLSSHITMSSSAF 69
Query: 604 NAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLL----AKPKLGFP- 658
A+ ++ G +P + V N S S P+ + + P + + G P
Sbjct: 70 PASPQQHAGSNPGQRVTTTYNQSPASFLSSILPSQPDYNSSKIPSAMDSNYQQSSAGQPI 129
Query: 659 -KKASRTARI-----ASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRL 712
K S+TA D EIQG+K+A+IQDLERKL+ K+ LL+NG RLTYEE+MARRL
Sbjct: 130 NAKPSQTANAKPIPRTPDHEIQGSKEALIQDLERKLKCKDTLLHNGNQRLTYEEKMARRL 189
Query: 713 LG-ADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPV 771
LG ++A VF Q+ +Q++ +S RL ++ RS GD V D
Sbjct: 190 LGPQNAAAVFQAQDDSGAQDSQQH--NSEHARL--QVPTSQVRSRSTSRGD-VNDQDAIQ 244
Query: 772 ENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLD 831
E P F ++ I EG +V+G P P + W+ +G+ + H I +
Sbjct: 245 EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE-K 303
Query: 832 GTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPR 891
G SL D G Y +A N G + T +L V A
Sbjct: 304 GLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA--------------------- 342
Query: 892 SRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV 951
+E P F+ P V EG +++C++S +P P L W+ + + V
Sbjct: 343 -------------KEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMV 389
Query: 952 RPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
+ ++ L ++N G +L+I+ V +DAG YT A N AG + + L V A+
Sbjct: 390 QFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 443
Score = 61.2 bits (147), Expect = 5e-09
Identities = 103/517 (19%), Positives = 178/517 (34%), Gaps = 131/517 (25%)
Query: 54 ETEDFDSEKEISQIFSTSPASLCEHPSHKETKLGEHASRRPQDNRSTPVQPLAEKQTKSI 113
ET F S+ + S I P E + L H + ++P Q + +
Sbjct: 27 ETSSFSSQTKQSSII-IQPRQCTEQRFSASSTLSSHITMSSSAFPASPQQHAGSNPGQRV 85
Query: 114 SSPVSKRKPAM--SPLLTRPSYIRSLRKAEKRGAKTPSTNVKPKTPHQRKGGPQSQLCDK 171
++ ++ + S L ++P Y +K PS + G P + +
Sbjct: 86 TTTYNQSPASFLSSILPSQPDY---------NSSKIPSA-MDSNYQQSSAGQPINAKPSQ 135
Query: 172 AANLIEELTSIFKAAKPRNRSPNGESSSPDSGYLSPKNQP----SALLSASASQSPMEDQ 227
AN AKP R+P+ E + + LL + E++
Sbjct: 136 TAN-----------AKPIPRTPDHEIQGSKEALIQDLERKLKCKDTLLHNGNQRLTYEEK 184
Query: 228 GEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAA----------------- 270
M R + P QD + + + H H+ L P +
Sbjct: 185 --MARRLLGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDA 242
Query: 271 -------PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEG 323
PRFIQ + + EG ++ +V+G P P V W+ G+ + +
Sbjct: 243 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTV----------QS 292
Query: 324 GDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAM 383
DLH +I++E G ++ + E ++D+ + + K+RAG
Sbjct: 293 DDLHKMIVSEK-----GLHSLI---------------FEVVRASDAGAYACVAKNRAG-- 330
Query: 384 PQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVF 443
+ T +V L + + K P+F
Sbjct: 331 ----EATFTVQLDVLAKEHKRA-----------------------------------PMF 351
Query: 444 TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEI 503
+ Q+ V EG V LEC++ PP ++ W R +Q + D L +
Sbjct: 352 IYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV----- 406
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
TL+I + +DAG +T SA N+ G T +L VT+
Sbjct: 407 -TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTA 442
Score = 57.0 bits (136), Expect = 1e-07
Identities = 47/194 (24%), Positives = 81/194 (41%), Gaps = 24/194 (12%)
Query: 414 LSVPVQQVHSPTSY---LCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPL 470
L VP QV S ++ + D ++PP F + +N ++ EG+ ++ +V G P
Sbjct: 220 LQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAP 279
Query: 471 QVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSA 530
V W+ G +Q +++ + + +L+ DAG + C A+N G A
Sbjct: 280 DVSWYLNGRTVQSDDLHKMI-------VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEA 332
Query: 531 TSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNP 590
T T QL V + + F + P +LE S++L +I + P
Sbjct: 333 TFTVQLDVLAKEHKRAPM----------FIYKPQSKKVLEGDSVKL----ECQISAIPPP 378
Query: 591 ELGLSRAALQMQFN 604
+L R +QFN
Sbjct: 379 KLFWKRNNEMVQFN 392
Score = 55.5 bits (132), Expect = 3e-07
Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 1/105 (0%)
Query: 1002 AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQ 1061
A +E PP FI+ +N + +G R++ +V G+P P + W ++ S D M
Sbjct: 242 AIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTV-QSDDLHKMIV 300
Query: 1062 DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISRH 1106
G L+ + DAG Y AKN AG + T +LDV H
Sbjct: 301 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEH 345
>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
Length = 1794
Score = 193 bits (491), Expect = 7e-49
Identities = 213/855 (24%), Positives = 320/855 (37%), Gaps = 149/855 (17%)
Query: 259 PQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQ 318
P ++ AP FI R+ + EG+ E RV G P P+V W G+ + +
Sbjct: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
Query: 319 IHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKS 378
+ C +L+I E+D G+YTC ATN SG+ + E+ +EG+ F
Sbjct: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS-----------FAK 129
Query: 379 RAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAY 438
+ G VS T+G V T RP +
Sbjct: 130 QLGQ--------PVVSKTLGDRFSAPAVET---------------------RP--SIWGE 158
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
PP F +L V EGQ+ C++ G P QV W + +Q P R+ S +
Sbjct: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ--PSARV------SVS 210
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDH 558
E + L I +D G++TC N G A+ +A+L + ++ N S+
Sbjct: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF---------- 260
Query: 559 FQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRG 618
+ ET + +K E+ V + E L AA + N P RG
Sbjct: 261 ---------VRETKATNSDVRK--EVTNVISKESKLD------SLEAAAKSKNCSSPQRG 303
Query: 619 VNGLINGKANSNKSLPTPAVLLSPTKEP-----PPLLAKPKLGFPKKASRTARIASDEEI 673
G ANS P + L S P P+L K +A AR+ +
Sbjct: 304 --GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA---ARVQPEPRA 358
Query: 674 QGTKDAVIQDLERKLRF--KEDLLNNGQPRLTYEE---RMARRLLGADSATVFNIQEPEE 728
G ERK + QP L ++ + A R + + + E
Sbjct: 359 PGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFES 418
Query: 729 ETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKI 788
+ +QE K + +++R E V E +AP F LK +
Sbjct: 419 KPQSQEVKENQT-------VKFRCEGLAVME---------------VAPSFSSVLKDCAV 456
Query: 789 FEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGN 848
EG C V G P P+I W +G+ I Y G LH + +D G
Sbjct: 457 IEGQDFVLQCSVRGTPVPRITWLLNGQPIQ-----YARSTCEAGVAELHIQDALPEDHGT 511
Query: 849 YTIMAANPQGRISCTGRLMVQAVNQRGRS----PRSPSGHPHVRRPRSRSRDSGDENEPI 904
YT +A N G++SC+ + V +S P +PS +P +
Sbjct: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS------KPTA------------ 553
Query: 905 QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 964
P FLQ DL V +G M +VSG P P++ W +G ++ +S +
Sbjct: 554 ------PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRG 606
Query: 965 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADG 1024
HSL I+ V D G YTC A N AG+ L V P FI K ++ + G
Sbjct: 607 TQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLG 666
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
V + C + G P P + W ++ ++L T + Q N L+++ AG Y +
Sbjct: 667 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-NEDVFTLVLKKVQPWHAGQYEI 725
Query: 1085 SAKNEAGIVSCTARL 1099
KN G SC L
Sbjct: 726 LLKNRVGECSCQVSL 740
Score = 118 bits (295), Expect = 4e-26
Identities = 179/778 (23%), Positives = 282/778 (36%), Gaps = 108/778 (13%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P AP F+Q L +V +GS+V + +V+GNP P V W G E+ + D + G H
Sbjct: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQH 609
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387
+L I E F +DTG YTC A N +G T A + ++ + G P
Sbjct: 610 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ--------------EPHDGTQPWFI 655
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT-TTAYFPPVFTKE 446
K SV+ ++G S + + I P LC+ G VFT
Sbjct: 656 SKPRSVTASLGQSV----LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
Query: 447 LQNTAVAE-GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICT 505
L+ GQ +L G QV Q S + P + R A E++C
Sbjct: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP-------RGREPASCEDLC- 763
Query: 506 LVIAETFPEDAGIFTCSARND-YGSATSTAQLVVTSANTENCSYESMGES---------- 554
G+ +D YGS A + E GE
Sbjct: 764 ---------GGGVGADGGGSDRYGSLRPG-----WPARGQGWLEEEDGEDVRGVLKRRVE 809
Query: 555 NNDHFQHFPPPPPILETSSLELASKKPS-------EIQQVNNPELGLSRAALQMQFN--A 605
H + + + +L KK S +++++ ++ RA LQ Q
Sbjct: 810 TRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDF-RANLQRQVKPKT 868
Query: 606 AERETNGVHPSRGVN-GLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPK----LGFPKK 660
E VH + V+ + K ++K TP P K PPP A P LG KK
Sbjct: 869 VSEEERKVHSPQQVDFRSVLAKKGTSK---TPV----PEKVPPPKPATPDFRSVLGGKKK 921
Query: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQP----RLTYEERMARRLLGAD 716
+S E L K L+N QP + + A L
Sbjct: 922 LPAENGSSSAET-----------LNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMG 970
Query: 717 SATVFNIQEPEEETANQEYKVSSCEQRLISEI--EYRLERSPVDESGDEVQYGDVPVENG 774
+A +P E S+ ++ L ++ + +R + +E + G
Sbjct: 971 NAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKR----SESQG 1026
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
AP F+ KL+ + EG + C+V+ +P I W +GK + K+ + I C
Sbjct: 1027 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLC 1084
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ--AVNQRGRSPRSPSGHPHVRRP-- 890
S+ + +D G Y +A N G+ C+ ++ V ++ ++P S P P
Sbjct: 1085 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1144
Query: 891 RSRSRDSGDENEPI----QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL 946
D+ + +P + P +Q P D V+ G+ + KV+G +W
Sbjct: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
Query: 947 DGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
K ++ K+ ENG L I G YT + N+ G + L V K
Sbjct: 1205 FRKQIQESEHMKVENSENG-SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
Score = 104 bits (260), Expect = 4e-22
Identities = 120/462 (25%), Positives = 178/462 (38%), Gaps = 111/462 (24%)
Query: 108 KQTKSISSPVSKRKPAMSPLLTRPSYIRSLRKAEK--------RGAKTP-STNVKPKTPH 158
++TK+ +S V K ++ ++++ S + SL A K RG P + N +P+ P
Sbjct: 262 RETKATNSDVRKE---VTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
Query: 159 QRK---------GGPQSQLCDKAANLIEELTSIFKAAKPRNR-----SPNGESS---SPD 201
+ K PQ+ + K ++ I L + +PR SP+GE +P
Sbjct: 319 ESKLESCKDSPRTAPQTPVLQKTSSSIT-LQAARVQPEPRAPGLGVLSPSGEERKRPAPP 377
Query: 202 SGYLSPKNQPS-----ALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRK 256
P QP + A+ + PME Q R+ P Q + V N+
Sbjct: 378 RPATFPTRQPGLGSQDVVSKAANRRIPMEGQ----RDSAFPKFESKPQSQE---VKENQT 430
Query: 257 SHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD 316
+ AP F L+ V EG L+C V G P PR+ W G+ +
Sbjct: 431 VKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-- 488
Query: 317 IQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAF 376
+ CE G + L I +A +D G YTCLA N G + SA V + S+ SE L
Sbjct: 489 -RSTCEAG-VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS-RKSEYL-- 543
Query: 377 KSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTT 436
+P A K T+
Sbjct: 544 ------LPVAPSKPTA-------------------------------------------- 553
Query: 437 AYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRS 496
P+F + L + V +G V + +V G PP +V W G+EIQ+S DF Q+ +
Sbjct: 554 ----PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
Query: 497 TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+L I E FPED G +TC A N G + A L V
Sbjct: 610 --------SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
Score = 99.0 bits (245), Expect = 2e-20
Identities = 66/220 (30%), Positives = 95/220 (43%), Gaps = 31/220 (14%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F+ P +L ++EG + + +V G P P ++W +G+P+ + G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK---------------------- 1008
I V D G YTC ATN +G ++EL V A +
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
Query: 1009 -------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQ 1061
PP F KL V +G R C++ G P PQ+ W K N L S RVS+ +
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA-RVSVSE 211
Query: 1062 DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
N G L I G ++D G YT N +G S +A L +
Sbjct: 212 KN-GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 93.6 bits (231), Expect = 9e-19
Identities = 66/206 (32%), Positives = 91/206 (44%), Gaps = 22/206 (10%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F D V EG+ + C V G P P ++W L+G+P++ + E GV L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCEAGVAELH 500
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP--------------PVFIEKL 1016
I+ D G YTC+A N GQ S S + V K++ + P+F++ L
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
Query: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHG-YICLLIQGAT 1075
+ V DG V + +V G PPP++ W + S D H + G L IQ
Sbjct: 561 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED---FHFEQRGTQHSLCIQEVF 617
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDV 1101
ED G YT A N AG V A L V
Sbjct: 618 PEDTGTYTCEAWNSAGEVRTQAVLTV 643
Score = 85.5 bits (210), Expect = 3e-16
Identities = 100/418 (23%), Positives = 177/418 (42%), Gaps = 67/418 (16%)
Query: 140 AEKRGAKTPSTNV----KPKTPHQRK--GGPQSQLCDKAANLIEELTS-IFKAAKP-RNR 191
A+K +KTP KP TP R GG + + ++ E L + +++KP N
Sbjct: 889 AKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNA 948
Query: 192 SPNGE----SSSPDSGYLSPKN--QPSALLSASASQSPMED-----QGEMEREVKSPGAR 240
P+G ++ + L P +P+ L + P E+ + E++++VK+
Sbjct: 949 QPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDV-- 1006
Query: 241 HCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTP 300
+C + + + ++S Q AP F QKL+ VAEG ++ L+C+V+ +P
Sbjct: 1007 NCKRGHAG-TTDNEKRSESQG-------TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1058
Query: 301 RVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVF 360
+ W GK L T I I + G L ++ I +A +D G Y C+A N +G S +V
Sbjct: 1059 TIIWTLNGKTLKTTKFI-ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVT 1117
Query: 361 IEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQ 420
++ A +++ ++++ KSR + +S+ +G+ S T V++
Sbjct: 1118 VDDAPASE-NTKAPEMKSR--------RPKSSLPPVLGTESDAT-------------VKK 1155
Query: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
+P + A PP + ++ V G+ V L +V G P+ W + +
Sbjct: 1156 KPAPKT-------PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
Query: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
IQ+S ++ E L I E G +T N GS + L V
Sbjct: 1209 IQESEHMKV--------ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
Score = 77.0 bits (188), Expect = 9e-14
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P+F ++ ++ EG F C++ G P P++ WFKD + I +S H+ I D DG CSL
Sbjct: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHFQIDYDEDGNCSL 1747
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQ 873
+ DDD YT A N G +CT L+V+ + +
Sbjct: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
Score = 70.1 bits (170), Expect = 1e-11
Identities = 47/150 (31%), Positives = 70/150 (46%), Gaps = 4/150 (2%)
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER--FFRPHFLQ 915
GR+S M+ ++ R S SP+ + + S S E + E +P+F +
Sbjct: 1636 GRLSSMA--MISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1693
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
DL V EG R DCK+ G P P++ W D + +R ++ E+G SLII V
Sbjct: 1694 TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1753
Query: 976 SRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
D YTC A N G+ + + EL+V E
Sbjct: 1754 GDDDAKYTCKAVNSLGEATCTAELIVETME 1783
Score = 67.8 bits (164), Expect = 5e-11
Identities = 33/102 (32%), Positives = 52/102 (50%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F + +R EV EGS +C++ G P P V WF + + + + QI + +LI
Sbjct: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372
I++ DD +YTC A N G T +AE+ +E + + E
Sbjct: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1790
Score = 63.9 bits (154), Expect = 8e-10
Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 7/98 (7%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P F+K +++ V EG +C++ G P +V WF+ I++S F+I +
Sbjct: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-------DYDE 1741
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ C+L+I++ +D +TC A N G AT TA+L+V
Sbjct: 1742 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
Score = 63.5 bits (153), Expect = 1e-09
Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 45/233 (19%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F Q D+ V EGK + C+VS P + W L+GK ++ + +L +E + S+
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGSLCSVS 1087
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVV----------------------------- 1001
IE D G+Y C+A N AGQ S ++ V
Sbjct: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
Query: 1002 -------------AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENE 1048
+A PP I+ ++ V G V L +V G P W K +
Sbjct: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
Query: 1049 SLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
+ S + +N + +L A +E G YT+ +N+ G L V
Sbjct: 1208 QIQESEHMKVENSENGSKLTIL--AARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
Score = 60.8 bits (146), Expect = 7e-09
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
VA ++ H P F + +++ V +G R +C++ G P P++ W K+++S+ S +
Sbjct: 1680 VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR-HFQID 1738
Query: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
D G L+I +D YT A N G +CTA L V
Sbjct: 1739 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 5/93 (5%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
P F L++ V +G L+C V G P P+I W + + ++ G L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA-----GVAEL 499
Query: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDVY 1102
IQ A ED G YT A+N G VSC+A + V+
Sbjct: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
Score = 47.8 bits (112), Expect = 6e-05
Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Query: 266 HFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL-HNTPDIQIHCEGG 324
H P FI K RS + G V + C + G+P P V W +GK L +T ++ +
Sbjct: 647 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV-LQNE 705
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASS 366
D+ TL++ + G+Y L N G + + ++ +S+
Sbjct: 706 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 193 bits (491), Expect = 7e-49
Identities = 213/855 (24%), Positives = 320/855 (37%), Gaps = 149/855 (17%)
Query: 259 PQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQ 318
P ++ AP FI R+ + EG+ E RV G P P+V W G+ + +
Sbjct: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
Query: 319 IHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKS 378
+ C +L+I E+D G+YTC ATN SG+ + E+ +EG+ F
Sbjct: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS-----------FAK 129
Query: 379 RAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAY 438
+ G VS T+G V T RP +
Sbjct: 130 QLGQ--------PVVSKTLGDRFSAPAVET---------------------RP--SIWGE 158
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
PP F +L V EGQ+ C++ G P QV W + +Q P R+ S +
Sbjct: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ--PSARV------SVS 210
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDH 558
E + L I +D G++TC N G A+ +A+L + ++ N S+
Sbjct: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF---------- 260
Query: 559 FQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRG 618
+ ET + +K E+ V + E L AA + N P RG
Sbjct: 261 ---------VRETKATNSDVRK--EVTNVISKESKLD------SLEAAAKSKNCSSPQRG 303
Query: 619 VNGLINGKANSNKSLPTPAVLLSPTKEP-----PPLLAKPKLGFPKKASRTARIASDEEI 673
G ANS P + L S P P+L K +A AR+ +
Sbjct: 304 --GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA---ARVQPEPRA 358
Query: 674 QGTKDAVIQDLERKLRF--KEDLLNNGQPRLTYEE---RMARRLLGADSATVFNIQEPEE 728
G ERK + QP L ++ + A R + + + E
Sbjct: 359 PGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFES 418
Query: 729 ETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKI 788
+ +QE K + +++R E V E +AP F LK +
Sbjct: 419 KPQSQEVKENQT-------VKFRCEGLAVME---------------VAPSFSSVLKDCAV 456
Query: 789 FEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGN 848
EG C V G P P+I W +G+ I Y G LH + +D G
Sbjct: 457 IEGQDFVLQCSVRGTPVPRITWLLNGQPIQ-----YARSTCEAGVAELHIQDALPEDHGT 511
Query: 849 YTIMAANPQGRISCTGRLMVQAVNQRGRS----PRSPSGHPHVRRPRSRSRDSGDENEPI 904
YT +A N G++SC+ + V +S P +PS +P +
Sbjct: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS------KPTA------------ 553
Query: 905 QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 964
P FLQ DL V +G M +VSG P P++ W +G ++ +S +
Sbjct: 554 ------PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRG 606
Query: 965 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADG 1024
HSL I+ V D G YTC A N AG+ L V P FI K ++ + G
Sbjct: 607 TQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLG 666
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
V + C + G P P + W ++ ++L T + Q N L+++ AG Y +
Sbjct: 667 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-NEDVFTLVLKKVQPWHAGQYEI 725
Query: 1085 SAKNEAGIVSCTARL 1099
KN G SC L
Sbjct: 726 LLKNRVGECSCQVSL 740
Score = 118 bits (295), Expect = 4e-26
Identities = 179/778 (23%), Positives = 282/778 (36%), Gaps = 108/778 (13%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P AP F+Q L +V +GS+V + +V+GNP P V W G E+ + D + G H
Sbjct: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQH 609
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387
+L I E F +DTG YTC A N +G T A + ++ + G P
Sbjct: 610 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ--------------EPHDGTQPWFI 655
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT-TTAYFPPVFTKE 446
K SV+ ++G S + + I P LC+ G VFT
Sbjct: 656 SKPRSVTASLGQSV----LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
Query: 447 LQNTAVAE-GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICT 505
L+ GQ +L G QV Q S + P + R A E++C
Sbjct: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP-------RGREPASCEDLC- 763
Query: 506 LVIAETFPEDAGIFTCSARND-YGSATSTAQLVVTSANTENCSYESMGES---------- 554
G+ +D YGS A + E GE
Sbjct: 764 ---------GGGVGADGGGSDRYGSLRPG-----WPARGQGWLEEEDGEDVRGVLKRRVE 809
Query: 555 NNDHFQHFPPPPPILETSSLELASKKPS-------EIQQVNNPELGLSRAALQMQFN--A 605
H + + + +L KK S +++++ ++ RA LQ Q
Sbjct: 810 TRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDF-RANLQRQVKPKT 868
Query: 606 AERETNGVHPSRGVN-GLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPK----LGFPKK 660
E VH + V+ + K ++K TP P K PPP A P LG KK
Sbjct: 869 VSEEERKVHSPQQVDFRSVLAKKGTSK---TPV----PEKVPPPKPATPDFRSVLGGKKK 921
Query: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQP----RLTYEERMARRLLGAD 716
+S E L K L+N QP + + A L
Sbjct: 922 LPAENGSSSAET-----------LNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMG 970
Query: 717 SATVFNIQEPEEETANQEYKVSSCEQRLISEI--EYRLERSPVDESGDEVQYGDVPVENG 774
+A +P E S+ ++ L ++ + +R + +E + G
Sbjct: 971 NAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKR----SESQG 1026
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
AP F+ KL+ + EG + C+V+ +P I W +GK + K+ + I C
Sbjct: 1027 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLC 1084
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ--AVNQRGRSPRSPSGHPHVRRP-- 890
S+ + +D G Y +A N G+ C+ ++ V ++ ++P S P P
Sbjct: 1085 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1144
Query: 891 RSRSRDSGDENEPI----QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL 946
D+ + +P + P +Q P D V+ G+ + KV+G +W
Sbjct: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
Query: 947 DGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
K ++ K+ ENG L I G YT + N+ G + L V K
Sbjct: 1205 FRKQIQESEHMKVENSENG-SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
Score = 104 bits (260), Expect = 4e-22
Identities = 120/462 (25%), Positives = 178/462 (38%), Gaps = 111/462 (24%)
Query: 108 KQTKSISSPVSKRKPAMSPLLTRPSYIRSLRKAEK--------RGAKTP-STNVKPKTPH 158
++TK+ +S V K ++ ++++ S + SL A K RG P + N +P+ P
Sbjct: 262 RETKATNSDVRKE---VTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
Query: 159 QRK---------GGPQSQLCDKAANLIEELTSIFKAAKPRNR-----SPNGESS---SPD 201
+ K PQ+ + K ++ I L + +PR SP+GE +P
Sbjct: 319 ESKLESCKDSPRTAPQTPVLQKTSSSIT-LQAARVQPEPRAPGLGVLSPSGEERKRPAPP 377
Query: 202 SGYLSPKNQPS-----ALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRK 256
P QP + A+ + PME Q R+ P Q + V N+
Sbjct: 378 RPATFPTRQPGLGSQDVVSKAANRRIPMEGQ----RDSAFPKFESKPQSQE---VKENQT 430
Query: 257 SHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD 316
+ AP F L+ V EG L+C V G P PR+ W G+ +
Sbjct: 431 VKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-- 488
Query: 317 IQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAF 376
+ CE G + L I +A +D G YTCLA N G + SA V + S+ SE L
Sbjct: 489 -RSTCEAG-VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS-RKSEYL-- 543
Query: 377 KSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTT 436
+P A K T+
Sbjct: 544 ------LPVAPSKPTA-------------------------------------------- 553
Query: 437 AYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRS 496
P+F + L + V +G V + +V G PP +V W G+EIQ+S DF Q+ +
Sbjct: 554 ----PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
Query: 497 TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+L I E FPED G +TC A N G + A L V
Sbjct: 610 --------SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
Score = 99.0 bits (245), Expect = 2e-20
Identities = 66/220 (30%), Positives = 95/220 (43%), Gaps = 31/220 (14%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F+ P +L ++EG + + +V G P P ++W +G+P+ + G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK---------------------- 1008
I V D G YTC ATN +G ++EL V A +
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
Query: 1009 -------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQ 1061
PP F KL V +G R C++ G P PQ+ W K N L S RVS+ +
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA-RVSVSE 211
Query: 1062 DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
N G L I G ++D G YT N +G S +A L +
Sbjct: 212 KN-GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 93.6 bits (231), Expect = 9e-19
Identities = 66/206 (32%), Positives = 91/206 (44%), Gaps = 22/206 (10%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F D V EG+ + C V G P P ++W L+G+P++ + E GV L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCEAGVAELH 500
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP--------------PVFIEKL 1016
I+ D G YTC+A N GQ S S + V K++ + P+F++ L
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
Query: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHG-YICLLIQGAT 1075
+ V DG V + +V G PPP++ W + S D H + G L IQ
Sbjct: 561 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED---FHFEQRGTQHSLCIQEVF 617
Query: 1076 KEDAGWYTVSAKNEAGIVSCTARLDV 1101
ED G YT A N AG V A L V
Sbjct: 618 PEDTGTYTCEAWNSAGEVRTQAVLTV 643
Score = 85.5 bits (210), Expect = 3e-16
Identities = 100/418 (23%), Positives = 177/418 (42%), Gaps = 67/418 (16%)
Query: 140 AEKRGAKTPSTNV----KPKTPHQRK--GGPQSQLCDKAANLIEELTS-IFKAAKP-RNR 191
A+K +KTP KP TP R GG + + ++ E L + +++KP N
Sbjct: 889 AKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNA 948
Query: 192 SPNGE----SSSPDSGYLSPKN--QPSALLSASASQSPMED-----QGEMEREVKSPGAR 240
P+G ++ + L P +P+ L + P E+ + E++++VK+
Sbjct: 949 QPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDV-- 1006
Query: 241 HCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTP 300
+C + + + ++S Q AP F QKL+ VAEG ++ L+C+V+ +P
Sbjct: 1007 NCKRGHAG-TTDNEKRSESQG-------TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1058
Query: 301 RVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVF 360
+ W GK L T I I + G L ++ I +A +D G Y C+A N +G S +V
Sbjct: 1059 TIIWTLNGKTLKTTKFI-ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVT 1117
Query: 361 IEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQ 420
++ A +++ ++++ KSR + +S+ +G+ S T V++
Sbjct: 1118 VDDAPASE-NTKAPEMKSR--------RPKSSLPPVLGTESDAT-------------VKK 1155
Query: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
+P + A PP + ++ V G+ V L +V G P+ W + +
Sbjct: 1156 KPAPKT-------PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
Query: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
IQ+S ++ E L I E G +T N GS + L V
Sbjct: 1209 IQESEHMKV--------ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
Score = 77.0 bits (188), Expect = 9e-14
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P+F ++ ++ EG F C++ G P P++ WFKD + I +S H+ I D DG CSL
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHFQIDYDEDGNCSL 1798
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQ 873
+ DDD YT A N G +CT L+V+ + +
Sbjct: 1799 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1835
Score = 70.1 bits (170), Expect = 1e-11
Identities = 47/150 (31%), Positives = 70/150 (46%), Gaps = 4/150 (2%)
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER--FFRPHFLQ 915
GR+S M+ ++ R S SP+ + + S S E + E +P+F +
Sbjct: 1687 GRLSSMA--MISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1744
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
DL V EG R DCK+ G P P++ W D + +R ++ E+G SLII V
Sbjct: 1745 TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1804
Query: 976 SRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
D YTC A N G+ + + EL+V E
Sbjct: 1805 GDDDAKYTCKAVNSLGEATCTAELIVETME 1834
Score = 67.8 bits (164), Expect = 5e-11
Identities = 33/102 (32%), Positives = 52/102 (50%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F + +R EV EGS +C++ G P P V WF + + + + QI + +LI
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372
I++ DD +YTC A N G T +AE+ +E + + E
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1841
Score = 63.9 bits (154), Expect = 8e-10
Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 7/98 (7%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P F+K +++ V EG +C++ G P +V WF+ I++S F+I +
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-------DYDE 1792
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ C+L+I++ +D +TC A N G AT TA+L+V
Sbjct: 1793 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830
Score = 63.5 bits (153), Expect = 1e-09
Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 45/233 (19%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F Q D+ V EGK + C+VS P + W L+GK ++ + +L +E + S+
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGSLCSVS 1087
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVV----------------------------- 1001
IE D G+Y C+A N AGQ S ++ V
Sbjct: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
Query: 1002 -------------AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENE 1048
+A PP I+ ++ V G V L +V G P W K +
Sbjct: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
Query: 1049 SLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
+ S + +N + +L A +E G YT+ +N+ G L V
Sbjct: 1208 QIQESEHMKVENSENGSKLTIL--AARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
Score = 60.8 bits (146), Expect = 7e-09
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
VA ++ H P F + +++ V +G R +C++ G P P++ W K+++S+ S +
Sbjct: 1731 VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR-HFQID 1789
Query: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
D G L+I +D YT A N G +CTA L V
Sbjct: 1790 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 5/93 (5%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
P F L++ V +G L+C V G P P+I W + + ++ G L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA-----GVAEL 499
Query: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDVY 1102
IQ A ED G YT A+N G VSC+A + V+
Sbjct: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
Score = 47.8 bits (112), Expect = 6e-05
Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Query: 266 HFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL-HNTPDIQIHCEGG 324
H P FI K RS + G V + C + G+P P V W +GK L +T ++ +
Sbjct: 647 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV-LQNE 705
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASS 366
D+ TL++ + G+Y L N G + + ++ +S+
Sbjct: 706 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 192 bits (489), Expect = 1e-48
Identities = 218/904 (24%), Positives = 333/904 (36%), Gaps = 178/904 (19%)
Query: 259 PQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQ 318
P ++ AP FI R+ + EG+ E RV G P P+V W G+ + +
Sbjct: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
Query: 319 IHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKS 378
+ C +L+I E+D G+YTC ATN SG+ + E+ +EG+ F
Sbjct: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS-----------FAK 129
Query: 379 RAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAY 438
+ G VS T+G V T RP +
Sbjct: 130 QLGQ--------PVVSKTLGDRFSAPAVET---------------------RP--SIWGE 158
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
PP F +L V EGQ+ C++ G P QV W + +Q P R+ S +
Sbjct: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ--PSARV------SVS 210
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV-------------------- 538
E + L I +D G++TC N G A+ +A+L +
Sbjct: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSD 270
Query: 539 -------------------TSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASK 579
+A ++NCS G S P PP S LE
Sbjct: 271 VRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPP---RESKLESCKD 327
Query: 580 KPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVL 639
P Q P L + +++ +Q + E P GV +G+ + P PA
Sbjct: 328 SPRTAPQT--PVLQKTSSSITLQAARVQPEPRA--PGLGVLSP-SGEERKRPAPPRPATF 382
Query: 640 LSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERK-----------L 688
PT++P LG S+ A E G +D+ E K +
Sbjct: 383 --PTRQPG-------LGSQDVVSKAANRRIPME--GQRDSAFPKFESKPQSQEVKENQTV 431
Query: 689 RFKEDLLNNGQPRLTY--EERMARRLLG-------ADSATVFNIQEPEEETANQEYKVSS 739
+F+ ++ +P + + E RR G A S + ++ ++ S+
Sbjct: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
Query: 740 CEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCR 799
+ +L ++ER V E +AP F LK + EG C
Sbjct: 492 AQGQLSCSWTLQVERLAVME---------------VAPSFSSVLKDCAVIEGQDFVLQCS 536
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGR 859
V G P P+I W +G+ I Y G LH + +D G YT +A N G+
Sbjct: 537 VRGTPVPRITWLLNGQPIQ-----YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
Query: 860 ISCTGRLMVQAVNQRGRS----PRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQ 915
+SC+ + V +S P +PS +P + P FLQ
Sbjct: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPS------KPTA------------------PIFLQ 627
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
DL V +G M +VSG P P++ W +G ++ +S + HSL I+ V
Sbjct: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLCIQEVF 686
Query: 976 SRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLG 1035
D G YTC A N AG+ L V P FI K ++ + G V + C + G
Sbjct: 687 PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAG 746
Query: 1036 VPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSC 1095
P P + W ++ ++L T + Q N L+++ AG Y + KN G SC
Sbjct: 747 DPFPTVHWLRDGKALCKDTGHFEVLQ-NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSC 805
Query: 1096 TARL 1099
L
Sbjct: 806 QVSL 809
Score = 127 bits (320), Expect = 4e-29
Identities = 97/340 (28%), Positives = 142/340 (41%), Gaps = 56/340 (16%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P FE K + ++ E V F C V+G PKP++ WF +G + + + D G+ L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA-GSHYL 472
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
+ D G Y+ A+N QG++SC+ L V+ +
Sbjct: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL------------------------- 507
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956
+ E P F D V EG+ + C V G P P ++W L+G+P++
Sbjct: 508 ------AVME--VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---- 555
Query: 957 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP------- 1009
+ E GV L I+ D G YTC+A N GQ S S + V K++ +
Sbjct: 556 YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
Query: 1010 -------PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD 1062
P+F++ L + V DG V + +V G PPP++ W + S D H +
Sbjct: 616 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED---FHFE 672
Query: 1063 NHG-YICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
G L IQ ED G YT A N AG V A L V
Sbjct: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
Score = 118 bits (295), Expect = 4e-26
Identities = 179/778 (23%), Positives = 282/778 (36%), Gaps = 108/778 (13%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P AP F+Q L +V +GS+V + +V+GNP P V W G E+ + D + G H
Sbjct: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQH 678
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387
+L I E F +DTG YTC A N +G T A + ++ + G P
Sbjct: 679 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ--------------EPHDGTQPWFI 724
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT-TTAYFPPVFTKE 446
K SV+ ++G S + + I P LC+ G VFT
Sbjct: 725 SKPRSVTASLGQSV----LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
Query: 447 LQNTAVAE-GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICT 505
L+ GQ +L G QV Q S + P + R A E++C
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP-------RGREPASCEDLC- 832
Query: 506 LVIAETFPEDAGIFTCSARND-YGSATSTAQLVVTSANTENCSYESMGES---------- 554
G+ +D YGS A + E GE
Sbjct: 833 ---------GGGVGADGGGSDRYGSLRPG-----WPARGQGWLEEEDGEDVRGVLKRRVE 878
Query: 555 NNDHFQHFPPPPPILETSSLELASKKPS-------EIQQVNNPELGLSRAALQMQFN--A 605
H + + + +L KK S +++++ ++ RA LQ Q
Sbjct: 879 TRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDF-RANLQRQVKPKT 937
Query: 606 AERETNGVHPSRGVN-GLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPK----LGFPKK 660
E VH + V+ + K ++K TP P K PPP A P LG KK
Sbjct: 938 VSEEERKVHSPQQVDFRSVLAKKGTSK---TPV----PEKVPPPKPATPDFRSVLGGKKK 990
Query: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQP----RLTYEERMARRLLGAD 716
+S E L K L+N QP + + A L
Sbjct: 991 LPAENGSSSAET-----------LNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMG 1039
Query: 717 SATVFNIQEPEEETANQEYKVSSCEQRLISEI--EYRLERSPVDESGDEVQYGDVPVENG 774
+A +P E S+ ++ L ++ + +R + +E + G
Sbjct: 1040 NAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKR----SESQG 1095
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
AP F+ KL+ + EG + C+V+ +P I W +GK + K+ + I C
Sbjct: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLC 1153
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ--AVNQRGRSPRSPSGHPHVRRP-- 890
S+ + +D G Y +A N G+ C+ ++ V ++ ++P S P P
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
Query: 891 RSRSRDSGDENEPI----QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL 946
D+ + +P + P +Q P D V+ G+ + KV+G +W
Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
Query: 947 DGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
K ++ K+ ENG L I G YT + N+ G + L V K
Sbjct: 1274 FRKQIQESEHMKVENSENG-SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
Score = 105 bits (263), Expect = 2e-22
Identities = 80/262 (30%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 850 TIMAAN--PQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD----SGDENEP 903
T+ AA P+ R G L ++ +P P+ P R+P S+D + + P
Sbjct: 346 TLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFP-TRQPGLGSQDVVSKAANRRIP 404
Query: 904 I--QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLV 961
+ Q P F P V+E + + C+VSG+P P+++W L+G PVR +
Sbjct: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
Query: 962 RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-PPVFIEKLQNTG 1020
+ G H L + +RD+G Y+C A+N GQ S S L V + P F L++
Sbjct: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
V +G L+C V G P P+I W + + ++ G L IQ A ED G
Sbjct: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA-----GVAELHIQDALPEDHG 579
Query: 1081 WYTVSAKNEAGIVSCTARLDVY 1102
YT A+N G VSC+A + V+
Sbjct: 580 TYTCLAENALGQVSCSAWVTVH 601
Score = 103 bits (257), Expect = 9e-22
Identities = 122/494 (24%), Positives = 196/494 (39%), Gaps = 106/494 (21%)
Query: 108 KQTKSISSPVSKRKPAMSPLLTRPSYIRSLRKAEK--------RGAKTP-STNVKPKTPH 158
++TK+ +S V K ++ ++++ S + SL A K RG P + N +P+ P
Sbjct: 262 RETKATNSDVRKE---VTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
Query: 159 QRK---------GGPQSQLCDKAANLIEELTSIFKAAKPRNRSPNGESSSPDSGYLSPKN 209
+ K PQ+ + K ++ I +AA+ + E +P G LSP
Sbjct: 319 ESKLESCKDSPRTAPQTPVLQKTSSSIT-----LQAARVQP-----EPRAPGLGVLSPSG 368
Query: 210 QPSALLSASASQS-PMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFP 268
+ + + P G ++V S A N+ + + R S
Sbjct: 369 EERKRPAPPRPATFPTRQPGLGSQDVVSKAA------NRRIPMEGQRDS----------- 411
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTP-DIQIHCEGGDLH 327
A P+F K +SQEV E V C V+G P P V WF EG + I+++ + G H
Sbjct: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS-H 470
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD-SDSESLAFKS-------- 378
L + +A D+G Y+C A+N G + S + +E + + + S S K
Sbjct: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQD 530
Query: 379 -------RAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQP------------------ 413
R +P+ + S+ + GV IQ
Sbjct: 531 FVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG 590
Query: 414 -------LSVPVQQVHSPTSYL--CRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRV 464
++V ++ + YL P T P+F + L + V +G V + +V
Sbjct: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA----PIFLQGLSDLKVMDGSQVTMTVQV 646
Query: 465 RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSAR 524
G PP +V W G+EIQ+S DF Q+ + +L I E FPED G +TC A
Sbjct: 647 SGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH--------SLCIQEVFPEDTGTYTCEAW 698
Query: 525 NDYGSATSTAQLVV 538
N G + A L V
Sbjct: 699 NSAGEVRTQAVLTV 712
Score = 99.0 bits (245), Expect = 2e-20
Identities = 66/220 (30%), Positives = 95/220 (43%), Gaps = 31/220 (14%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F+ P +L ++EG + + +V G P P ++W +G+P+ + G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK---------------------- 1008
I V D G YTC ATN +G ++EL V A +
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
Query: 1009 -------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQ 1061
PP F KL V +G R C++ G P PQ+ W K N L S RVS+ +
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA-RVSVSE 211
Query: 1062 DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
N G L I G ++D G YT N +G S +A L +
Sbjct: 212 KN-GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 89.7 bits (221), Expect = 1e-17
Identities = 68/255 (26%), Positives = 104/255 (40%), Gaps = 42/255 (16%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F L K+ +G VT T +V+GNP P++ W +G +I D + QR +
Sbjct: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
+ +D G YT A N G + L VQ PH
Sbjct: 682 IQEVFP--EDTGTYTCEAWNSAGEVRTQAVLTVQ--------------EPH--------- 716
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
G + P F+ P +T G+ + C ++G P P + W DGK + D+
Sbjct: 717 -DGTQ----------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAH-----KPP 1010
H +++ V +L+++ V AG Y + NR G+ S + L++ A + P
Sbjct: 766 GHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREP 825
Query: 1011 VFIEKLQNTGV-ADG 1024
E L GV ADG
Sbjct: 826 ASCEDLCGGGVGADG 840
Score = 85.5 bits (210), Expect = 3e-16
Identities = 100/418 (23%), Positives = 177/418 (42%), Gaps = 67/418 (16%)
Query: 140 AEKRGAKTPSTNV----KPKTPHQRK--GGPQSQLCDKAANLIEELTS-IFKAAKP-RNR 191
A+K +KTP KP TP R GG + + ++ E L + +++KP N
Sbjct: 958 AKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNA 1017
Query: 192 SPNGE----SSSPDSGYLSPKN--QPSALLSASASQSPMED-----QGEMEREVKSPGAR 240
P+G ++ + L P +P+ L + P E+ + E++++VK+
Sbjct: 1018 QPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDV-- 1075
Query: 241 HCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTP 300
+C + + + ++S Q AP F QKL+ VAEG ++ L+C+V+ +P
Sbjct: 1076 NCKRGHAG-TTDNEKRSESQG-------TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
Query: 301 RVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVF 360
+ W GK L T I I + G L ++ I +A +D G Y C+A N +G S +V
Sbjct: 1128 TIIWTLNGKTLKTTKFI-ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVT 1186
Query: 361 IEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQ 420
++ A +++ ++++ KSR + +S+ +G+ S T V++
Sbjct: 1187 VDDAPASE-NTKAPEMKSR--------RPKSSLPPVLGTESDAT-------------VKK 1224
Query: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
+P + A PP + ++ V G+ V L +V G P+ W + +
Sbjct: 1225 KPAPKT-------PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
Query: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
IQ+S ++ E L I E G +T N GS + L V
Sbjct: 1278 IQESEHMKV--------ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
Score = 77.0 bits (188), Expect = 9e-14
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P+F ++ ++ EG F C++ G P P++ WFKD + I +S H+ I D DG CSL
Sbjct: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHFQIDYDEDGNCSL 1816
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQ 873
+ DDD YT A N G +CT L+V+ + +
Sbjct: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
Score = 70.1 bits (170), Expect = 1e-11
Identities = 47/150 (31%), Positives = 70/150 (46%), Gaps = 4/150 (2%)
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER--FFRPHFLQ 915
GR+S M+ ++ R S SP+ + + S S E + E +P+F +
Sbjct: 1705 GRLSSMA--MISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1762
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
DL V EG R DCK+ G P P++ W D + +R ++ E+G SLII V
Sbjct: 1763 TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
Query: 976 SRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
D YTC A N G+ + + EL+V E
Sbjct: 1823 GDDDAKYTCKAVNSLGEATCTAELIVETME 1852
Score = 67.8 bits (164), Expect = 5e-11
Identities = 33/102 (32%), Positives = 52/102 (50%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F + +R EV EGS +C++ G P P V WF + + + + QI + +LI
Sbjct: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372
I++ DD +YTC A N G T +AE+ +E + + E
Sbjct: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1859
Score = 63.9 bits (154), Expect = 8e-10
Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 7/98 (7%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P F+K +++ V EG +C++ G P +V WF+ I++S F+I +
Sbjct: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-------DYDE 1810
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ C+L+I++ +D +TC A N G AT TA+L+V
Sbjct: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
Score = 63.5 bits (153), Expect = 1e-09
Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 45/233 (19%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F Q D+ V EGK + C+VS P + W L+GK ++ + +L +E + S+
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGSLCSVS 1156
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVV----------------------------- 1001
IE D G+Y C+A N AGQ S ++ V
Sbjct: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
Query: 1002 -------------AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENE 1048
+A PP I+ ++ V G V L +V G P W K +
Sbjct: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
Query: 1049 SLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
+ S + +N + +L A +E G YT+ +N+ G L V
Sbjct: 1277 QIQESEHMKVENSENGSKLTIL--AARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
Score = 60.8 bits (146), Expect = 7e-09
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
VA ++ H P F + +++ V +G R +C++ G P P++ W K+++S+ S +
Sbjct: 1749 VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR-HFQID 1807
Query: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
D G L+I +D YT A N G +CTA L V
Sbjct: 1808 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
Score = 47.8 bits (112), Expect = 6e-05
Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Query: 266 HFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL-HNTPDIQIHCEGG 324
H P FI K RS + G V + C + G+P P V W +GK L +T ++ +
Sbjct: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV-LQNE 774
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASS 366
D+ TL++ + G+Y L N G + + ++ +S+
Sbjct: 775 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 192 bits (489), Expect = 1e-48
Identities = 218/904 (24%), Positives = 333/904 (36%), Gaps = 178/904 (19%)
Query: 259 PQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQ 318
P ++ AP FI R+ + EG+ E RV G P P+V W G+ + +
Sbjct: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
Query: 319 IHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKS 378
+ C +L+I E+D G+YTC ATN SG+ + E+ +EG+ F
Sbjct: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS-----------FAK 129
Query: 379 RAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAY 438
+ G VS T+G V T RP +
Sbjct: 130 QLGQ--------PVVSKTLGDRFSAPAVET---------------------RP--SIWGE 158
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
PP F +L V EGQ+ C++ G P QV W + +Q P R+ S +
Sbjct: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ--PSARV------SVS 210
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV-------------------- 538
E + L I +D G++TC N G A+ +A+L +
Sbjct: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSD 270
Query: 539 -------------------TSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASK 579
+A ++NCS G S P PP S LE
Sbjct: 271 VRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPP---RESKLESCKD 327
Query: 580 KPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVL 639
P Q P L + +++ +Q + E P GV +G+ + P PA
Sbjct: 328 SPRTAPQT--PVLQKTSSSITLQAARVQPEPRA--PGLGVLSP-SGEERKRPAPPRPATF 382
Query: 640 LSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERK-----------L 688
PT++P LG S+ A E G +D+ E K +
Sbjct: 383 --PTRQPG-------LGSQDVVSKAANRRIPME--GQRDSAFPKFESKPQSQEVKENQTV 431
Query: 689 RFKEDLLNNGQPRLTY--EERMARRLLG-------ADSATVFNIQEPEEETANQEYKVSS 739
+F+ ++ +P + + E RR G A S + ++ ++ S+
Sbjct: 432 KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
Query: 740 CEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCR 799
+ +L ++ER V E +AP F LK + EG C
Sbjct: 492 AQGQLSCSWTLQVERLAVME---------------VAPSFSSVLKDCAVIEGQDFVLQCS 536
Query: 800 VAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGR 859
V G P P+I W +G+ I Y G LH + +D G YT +A N G+
Sbjct: 537 VRGTPVPRITWLLNGQPIQ-----YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
Query: 860 ISCTGRLMVQAVNQRGRS----PRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQ 915
+SC+ + V +S P +PS +P + P FLQ
Sbjct: 592 VSCSAWVTVHEKKSSRKSEYLLPVAPS------KPTA------------------PIFLQ 627
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
DL V +G M +VSG P P++ W +G ++ +S + HSL I+ V
Sbjct: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLCIQEVF 686
Query: 976 SRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLG 1035
D G YTC A N AG+ L V P FI K ++ + G V + C + G
Sbjct: 687 PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAG 746
Query: 1036 VPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSC 1095
P P + W ++ ++L T + Q N L+++ AG Y + KN G SC
Sbjct: 747 DPFPTVHWLRDGKALCKDTGHFEVLQ-NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSC 805
Query: 1096 TARL 1099
L
Sbjct: 806 QVSL 809
Score = 127 bits (320), Expect = 4e-29
Identities = 97/340 (28%), Positives = 142/340 (41%), Gaps = 56/340 (16%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P FE K + ++ E V F C V+G PKP++ WF +G + + + D G+ L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA-GSHYL 472
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
+ D G Y+ A+N QG++SC+ L V+ +
Sbjct: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL------------------------- 507
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956
+ E P F D V EG+ + C V G P P ++W L+G+P++
Sbjct: 508 ------AVME--VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---- 555
Query: 957 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP------- 1009
+ E GV L I+ D G YTC+A N GQ S S + V K++ +
Sbjct: 556 YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
Query: 1010 -------PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQD 1062
P+F++ L + V DG V + +V G PPP++ W + S D H +
Sbjct: 616 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED---FHFE 672
Query: 1063 NHG-YICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
G L IQ ED G YT A N AG V A L V
Sbjct: 673 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
Score = 118 bits (295), Expect = 4e-26
Identities = 179/778 (23%), Positives = 282/778 (36%), Gaps = 108/778 (13%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P AP F+Q L +V +GS+V + +V+GNP P V W G E+ + D + G H
Sbjct: 620 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQH 678
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387
+L I E F +DTG YTC A N +G T A + ++ + G P
Sbjct: 679 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ--------------EPHDGTQPWFI 724
Query: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT-TTAYFPPVFTKE 446
K SV+ ++G S + + I P LC+ G VFT
Sbjct: 725 SKPRSVTASLGQSV----LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
Query: 447 LQNTAVAE-GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICT 505
L+ GQ +L G QV Q S + P + R A E++C
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP-------RGREPASCEDLC- 832
Query: 506 LVIAETFPEDAGIFTCSARND-YGSATSTAQLVVTSANTENCSYESMGES---------- 554
G+ +D YGS A + E GE
Sbjct: 833 ---------GGGVGADGGGSDRYGSLRPG-----WPARGQGWLEEEDGEDVRGVLKRRVE 878
Query: 555 NNDHFQHFPPPPPILETSSLELASKKPS-------EIQQVNNPELGLSRAALQMQFN--A 605
H + + + +L KK S +++++ ++ RA LQ Q
Sbjct: 879 TRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDF-RANLQRQVKPKT 937
Query: 606 AERETNGVHPSRGVN-GLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPK----LGFPKK 660
E VH + V+ + K ++K TP P K PPP A P LG KK
Sbjct: 938 VSEEERKVHSPQQVDFRSVLAKKGTSK---TPV----PEKVPPPKPATPDFRSVLGGKKK 990
Query: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQP----RLTYEERMARRLLGAD 716
+S E L K L+N QP + + A L
Sbjct: 991 LPAENGSSSAET-----------LNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMG 1039
Query: 717 SATVFNIQEPEEETANQEYKVSSCEQRLISEI--EYRLERSPVDESGDEVQYGDVPVENG 774
+A +P E S+ ++ L ++ + +R + +E + G
Sbjct: 1040 NAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKR----SESQG 1095
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
AP F+ KL+ + EG + C+V+ +P I W +GK + K+ + I C
Sbjct: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLC 1153
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ--AVNQRGRSPRSPSGHPHVRRP-- 890
S+ + +D G Y +A N G+ C+ ++ V ++ ++P S P P
Sbjct: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
Query: 891 RSRSRDSGDENEPI----QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL 946
D+ + +P + P +Q P D V+ G+ + KV+G +W
Sbjct: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
Query: 947 DGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
K ++ K+ ENG L I G YT + N+ G + L V K
Sbjct: 1274 FRKQIQESEHMKVENSENG-SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
Score = 105 bits (263), Expect = 2e-22
Identities = 80/262 (30%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 850 TIMAAN--PQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD----SGDENEP 903
T+ AA P+ R G L ++ +P P+ P R+P S+D + + P
Sbjct: 346 TLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFP-TRQPGLGSQDVVSKAANRRIP 404
Query: 904 I--QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLV 961
+ Q P F P V+E + + C+VSG+P P+++W L+G PVR +
Sbjct: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
Query: 962 RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK-PPVFIEKLQNTG 1020
+ G H L + +RD+G Y+C A+N GQ S S L V + P F L++
Sbjct: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
V +G L+C V G P P+I W + + ++ G L IQ A ED G
Sbjct: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA-----GVAELHIQDALPEDHG 579
Query: 1081 WYTVSAKNEAGIVSCTARLDVY 1102
YT A+N G VSC+A + V+
Sbjct: 580 TYTCLAENALGQVSCSAWVTVH 601
Score = 103 bits (257), Expect = 9e-22
Identities = 122/494 (24%), Positives = 196/494 (39%), Gaps = 106/494 (21%)
Query: 108 KQTKSISSPVSKRKPAMSPLLTRPSYIRSLRKAEK--------RGAKTP-STNVKPKTPH 158
++TK+ +S V K ++ ++++ S + SL A K RG P + N +P+ P
Sbjct: 262 RETKATNSDVRKE---VTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
Query: 159 QRK---------GGPQSQLCDKAANLIEELTSIFKAAKPRNRSPNGESSSPDSGYLSPKN 209
+ K PQ+ + K ++ I +AA+ + E +P G LSP
Sbjct: 319 ESKLESCKDSPRTAPQTPVLQKTSSSIT-----LQAARVQP-----EPRAPGLGVLSPSG 368
Query: 210 QPSALLSASASQS-PMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFP 268
+ + + P G ++V S A N+ + + R S
Sbjct: 369 EERKRPAPPRPATFPTRQPGLGSQDVVSKAA------NRRIPMEGQRDS----------- 411
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTP-DIQIHCEGGDLH 327
A P+F K +SQEV E V C V+G P P V WF EG + I+++ + G H
Sbjct: 412 AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS-H 470
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD-SDSESLAFKS-------- 378
L + +A D+G Y+C A+N G + S + +E + + + S S K
Sbjct: 471 YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQD 530
Query: 379 -------RAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQP------------------ 413
R +P+ + S+ + GV IQ
Sbjct: 531 FVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG 590
Query: 414 -------LSVPVQQVHSPTSYL--CRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRV 464
++V ++ + YL P T P+F + L + V +G V + +V
Sbjct: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA----PIFLQGLSDLKVMDGSQVTMTVQV 646
Query: 465 RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSAR 524
G PP +V W G+EIQ+S DF Q+ + +L I E FPED G +TC A
Sbjct: 647 SGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH--------SLCIQEVFPEDTGTYTCEAW 698
Query: 525 NDYGSATSTAQLVV 538
N G + A L V
Sbjct: 699 NSAGEVRTQAVLTV 712
Score = 99.0 bits (245), Expect = 2e-20
Identities = 66/220 (30%), Positives = 95/220 (43%), Gaps = 31/220 (14%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F+ P +L ++EG + + +V G P P ++W +G+P+ + G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK---------------------- 1008
I V D G YTC ATN +G ++EL V A +
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
Query: 1009 -------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQ 1061
PP F KL V +G R C++ G P PQ+ W K N L S RVS+ +
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA-RVSVSE 211
Query: 1062 DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
N G L I G ++D G YT N +G S +A L +
Sbjct: 212 KN-GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 89.7 bits (221), Expect = 1e-17
Identities = 68/255 (26%), Positives = 104/255 (40%), Gaps = 42/255 (16%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F L K+ +G VT T +V+GNP P++ W +G +I D + QR +
Sbjct: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSR 895
+ +D G YT A N G + L VQ PH
Sbjct: 682 IQEVFP--EDTGTYTCEAWNSAGEVRTQAVLTVQ--------------EPH--------- 716
Query: 896 DSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS 955
G + P F+ P +T G+ + C ++G P P + W DGK + D+
Sbjct: 717 -DGTQ----------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
Query: 956 AHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAH-----KPP 1010
H +++ V +L+++ V AG Y + NR G+ S + L++ A + P
Sbjct: 766 GHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREP 825
Query: 1011 VFIEKLQNTGV-ADG 1024
E L GV ADG
Sbjct: 826 ASCEDLCGGGVGADG 840
Score = 85.5 bits (210), Expect = 3e-16
Identities = 100/418 (23%), Positives = 177/418 (42%), Gaps = 67/418 (16%)
Query: 140 AEKRGAKTPSTNV----KPKTPHQRK--GGPQSQLCDKAANLIEELTS-IFKAAKP-RNR 191
A+K +KTP KP TP R GG + + ++ E L + +++KP N
Sbjct: 958 AKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNA 1017
Query: 192 SPNGE----SSSPDSGYLSPKN--QPSALLSASASQSPMED-----QGEMEREVKSPGAR 240
P+G ++ + L P +P+ L + P E+ + E++++VK+
Sbjct: 1018 QPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDV-- 1075
Query: 241 HCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTP 300
+C + + + ++S Q AP F QKL+ VAEG ++ L+C+V+ +P
Sbjct: 1076 NCKRGHAG-TTDNEKRSESQG-------TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
Query: 301 RVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVF 360
+ W GK L T I I + G L ++ I +A +D G Y C+A N +G S +V
Sbjct: 1128 TIIWTLNGKTLKTTKFI-ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVT 1186
Query: 361 IEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQ 420
++ A +++ ++++ KSR + +S+ +G+ S T V++
Sbjct: 1187 VDDAPASE-NTKAPEMKSR--------RPKSSLPPVLGTESDAT-------------VKK 1224
Query: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
+P + A PP + ++ V G+ V L +V G P+ W + +
Sbjct: 1225 KPAPKT-------PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
Query: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
IQ+S ++ E L I E G +T N GS + L V
Sbjct: 1278 IQESEHMKV--------ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
Score = 77.0 bits (188), Expect = 9e-14
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P+F ++ ++ EG F C++ G P P++ WFKD + I +S H+ I D DG CSL
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHFQIDYDEDGNCSL 1867
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQ 873
+ DDD YT A N G +CT L+V+ + +
Sbjct: 1868 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1904
Score = 70.1 bits (170), Expect = 1e-11
Identities = 47/150 (31%), Positives = 70/150 (46%), Gaps = 4/150 (2%)
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER--FFRPHFLQ 915
GR+S M+ ++ R S SP+ + + S S E + E +P+F +
Sbjct: 1756 GRLSSMA--MISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1813
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
DL V EG R DCK+ G P P++ W D + +R ++ E+G SLII V
Sbjct: 1814 TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1873
Query: 976 SRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
D YTC A N G+ + + EL+V E
Sbjct: 1874 GDDDAKYTCKAVNSLGEATCTAELIVETME 1903
Score = 67.8 bits (164), Expect = 5e-11
Identities = 33/102 (32%), Positives = 52/102 (50%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F + +R EV EGS +C++ G P P V WF + + + + QI + +LI
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372
I++ DD +YTC A N G T +AE+ +E + + E
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1910
Score = 63.9 bits (154), Expect = 8e-10
Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 7/98 (7%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P F+K +++ V EG +C++ G P +V WF+ I++S F+I +
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-------DYDE 1861
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ C+L+I++ +D +TC A N G AT TA+L+V
Sbjct: 1862 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 63.5 bits (153), Expect = 1e-09
Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 45/233 (19%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F Q D+ V EGK + C+VS P + W L+GK ++ + +L +E + S+
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGSLCSVS 1156
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVV----------------------------- 1001
IE D G+Y C+A N AGQ S ++ V
Sbjct: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
Query: 1002 -------------AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENE 1048
+A PP I+ ++ V G V L +V G P W K +
Sbjct: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
Query: 1049 SLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
+ S + +N + +L A +E G YT+ +N+ G L V
Sbjct: 1277 QIQESEHMKVENSENGSKLTIL--AARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
Score = 60.8 bits (146), Expect = 7e-09
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
VA ++ H P F + +++ V +G R +C++ G P P++ W K+++S+ S +
Sbjct: 1800 VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR-HFQID 1858
Query: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
D G L+I +D YT A N G +CTA L V
Sbjct: 1859 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 47.8 bits (112), Expect = 6e-05
Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Query: 266 HFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL-HNTPDIQIHCEGG 324
H P FI K RS + G V + C + G+P P V W +GK L +T ++ +
Sbjct: 716 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV-LQNE 774
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASS 366
D+ TL++ + G+Y L N G + + ++ +S+
Sbjct: 775 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 136 bits (343), Expect = 1e-31
Identities = 189/888 (21%), Positives = 314/888 (35%), Gaps = 156/888 (17%)
Query: 251 VPHNRKSHPQPHSALHFPAAPRFIQ--KLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEG 308
V N Q H LH P K+ ++ V + V LEC+ GNP P + W+ +
Sbjct: 1899 VATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDN 1958
Query: 309 KELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD 368
+ L + + G + I A D G Y C+A N +G+ + + A S
Sbjct: 1959 RLLSGSTSMTFLNRG---QIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSIS 2015
Query: 369 SDSESLAFKSRAGAMPQAQKK-TTSVSLT-IGSSSPKTGVTTAVI-----QPLSVPVQQV 421
+ +A + + + + SLT + SP + + + + L++ Q+
Sbjct: 2016 GSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQI 2075
Query: 422 HSPTSYLC---------RPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQV 472
Y C + D Y PP E QN +V Q V L C+ PP +
Sbjct: 2076 SDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTL 2135
Query: 473 QWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARN------- 525
W + G + P I + + L I + +D G +TC A N
Sbjct: 2136 TWLKDGHPLLKKPGLSISENRS----------VLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 526 ----------DYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLE 575
+ G + QL V N + ES G PPP I +
Sbjct: 2186 NYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSG---------IPPPNLIWK----- 2231
Query: 576 LASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPT 635
KK S + + + + Q+Q + AE+ ++ N K N +
Sbjct: 2232 ---KKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYI 2288
Query: 636 PAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLL 695
+ + P ++ +R I+ + E+QG + +
Sbjct: 2289 RPTITNSGSHPTEIIV----------TRGKSISLECEVQGIPPPTVT-----------WM 2327
Query: 696 NNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERS 755
+G P + A+ + D + ++ + Y + +++ +Y L
Sbjct: 2328 KDGHPLIK-----AKGVEILDEGHILQLKNIHVSDTGR-YVCVAVNVAGMTDKKYDLS-- 2379
Query: 756 PVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGK 815
V + N +P ++ + E V+ TC +G P P I WFKDG
Sbjct: 2380 --------VHAPPSIIGNHRSP------ENISVVEKNSVSLTCEASGIPLPSITWFKDGW 2425
Query: 816 QISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRG 875
+S + R L G L +T++D G YT + N G +R
Sbjct: 2426 PVSLSNS----VRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE-------------ERK 2468
Query: 876 RSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVS 935
S PH+ + D+ V+E + + C+V+
Sbjct: 2469 IFGLSVLVPPHIVGENTLE------------------------DVKVKEKQSVTLTCEVT 2504
Query: 936 GLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSF 995
G P P+++W DG+P++ D AH ++ +G L I V G YTC+A++ AG S
Sbjct: 2505 GNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHKSR 2561
Query: 996 SLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTD 1055
S L V ++ V P L C PP I W K+ L + +
Sbjct: 2562 SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621
Query: 1056 RVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
+ G L I A +++AG Y+ A NEAG + + VYI
Sbjct: 2622 IRIL----PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYI 2665
Score = 128 bits (321), Expect = 3e-29
Identities = 190/887 (21%), Positives = 315/887 (35%), Gaps = 150/887 (16%)
Query: 288 VYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLAT 347
+ +ECR TG P P++ W G L + I++ G + I A D YTC+A+
Sbjct: 3360 INIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG---QVIRIVRAQVSDVAVYTCVAS 3416
Query: 348 NPSGSDTTSAEVFIEGASSTDSD---SESLAFKSRAGAMPQAQKKTTSVSLT-------I 397
N +G D + + + D+ E K + +M T + S+ +
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPL 3476
Query: 398 GSSSPKTGVTTA-VIQPLSVPVQQVHSPTSYLCRPDGTTTAYF------PPVF--TKELQ 448
G + T T V+Q L + T G + +F PP ++E +
Sbjct: 3477 GLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHE 3536
Query: 449 NTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVI 508
+V + L C G P ++ W + G + + + L E I T +
Sbjct: 3537 EISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL-----GGGEVLRISTAQV 3591
Query: 509 AETFPEDAGIFTCSARNDYGS---------------ATSTAQLVVTSANTENCSYESMGE 553
ED G +TC A + G A + +T + E +
Sbjct: 3592 -----EDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSD 3646
Query: 554 SNNDHFQHFPPPPPILETSSLELASKKP-------SEIQQVNNPELGLSRAALQMQFNAA 606
+ PPP I + E P Q+NN +LG + + N A
Sbjct: 3647 A--------VPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIA 3698
Query: 607 ERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKE--PPPLLAKPKLGFPKKASRT 664
+ T + V I G S L + +L E P P + K G +
Sbjct: 3699 GKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHA 3758
Query: 665 ARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLL-GADSATVF-- 721
+ + A + D R L + + R+ + + + G + TV
Sbjct: 3759 RYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVN 3818
Query: 722 ----------NIQEPE------------EETANQEYKVSSCEQRLIS---EIEYRLERSP 756
I +P ++ N +SS +IS + E +
Sbjct: 3819 VQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3878
Query: 757 VDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 816
+ +GD+ + D+ V+ + P + + + + P TC +G P P I+W K+G +
Sbjct: 3879 TNGAGDDKRTVDLTVQ--VPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIR 3936
Query: 817 ISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR 876
+ P+ D Y I + ++ A+ L+ G YT +A N G
Sbjct: 3937 LLPRGDGYRIL----SSGAIEILATQLNHAGRYTCVARNAAG------------------ 3974
Query: 877 SPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSG 936
S H HV +EP P P +L V + C+ +G
Sbjct: 3975 -----SAHRHVTL---------HVHEP-------PVIQPQPSELHVILNNPILLPCEATG 4013
Query: 937 LPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFS 996
P+P ++WQ +G V + ++ G+ I DAG Y C+A N AG
Sbjct: 4014 TPSPFITWQKEGINVNTSGRNHAVLPSGGLQ---ISRAVREDAGTYMCVAQNPAGTALGK 4070
Query: 997 LELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDR 1056
++L V PPV L+ +A P+ L C G+PPP I W K+ ++ S +
Sbjct: 4071 IKLNVQV-----PPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125
Query: 1057 VSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
+ + L I DAG YT A N AG S + +L V++
Sbjct: 4126 RVLSSGS-----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHV 4167
Score = 122 bits (307), Expect = 1e-27
Identities = 94/327 (28%), Positives = 140/327 (42%), Gaps = 58/327 (17%)
Query: 767 GDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTI 826
G + + + P LK Y I P+T +C G P P I W KDG+ I +I
Sbjct: 4069 GKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVE-----SI 4123
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH 886
++ + + SL D G+YT MAAN G S + +L V H
Sbjct: 4124 RQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV-----------------H 4166
Query: 887 VRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL 946
V PR RS + G TV E + C G+PTP ++W+
Sbjct: 4167 VP-PRIRSTE---------------------GHYTVNENSQAILPCVADGIPTPAINWKK 4204
Query: 947 DGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 1006
D + + K G LI+E V D+G YTC+A N AG+++ ++ L V
Sbjct: 4205 DNV-LLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV----- 4256
Query: 1007 HKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGY 1066
H P F E + + G +RL C+ G+P P++ W N + D V+ H +
Sbjct: 4257 HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSE---- 4312
Query: 1067 ICLLIQGATKEDAGWYTVSAKNEAGIV 1093
L+I+ +KED+G Y +A+N G V
Sbjct: 4313 --LVIERVSKEDSGTYVCTAENSVGFV 4337
Score = 122 bits (306), Expect = 2e-27
Identities = 195/886 (22%), Positives = 311/886 (35%), Gaps = 140/886 (15%)
Query: 290 LECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNP 349
L+C VTG+P P + W +G+ + +I G L+IA+A +TG Y C+A N
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNG---RKLVIAQAQVSNTGLYRCMAANT 1810
Query: 350 SGSDTTSAEVFIEGASSTDSD--SESLAFKSRAGAMPQAQKKTTSVSLT---------IG 398
+G EV + + S SE + K + A+ + S+T
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTA 1870
Query: 399 SSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF------PPVFTK--ELQNT 450
+ K + V+Q ++ T G T + PP ++ N
Sbjct: 1871 QGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNE 1930
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
V V LEC+ G P + W++ + S L + E +I
Sbjct: 1931 TVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQI------- 1983
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQ-----HFPPP 565
DAGI+ C A N G+ L V A + + S + N+ + P
Sbjct: 1984 ---SDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPA 2040
Query: 566 PPILETSSLELASKKPSEIQQVNNPE-LGLSRAALQ-------MQFNAAERETNGVHPSR 617
P + S + +Q ++ L L+ A + + NAA + +
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Query: 618 GVNGLINGKANSNKSLPTPAVLLSPTKE--PPPLLAKPKLGFPKKASRTARIASDEEIQG 675
V I G+ + L + AV L + PPP L K G P I+ + +
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLK 2160
Query: 676 TKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPE-------- 727
+DA +QD R ++ + + + G+D T + E
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCES 2220
Query: 728 ----------EETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAP 777
++ + S R++S R + + E D Y V
Sbjct: 2221 SGIPPPNLIWKKKGSPVLTDSMGRVRILSG--GRQLQISIAEKSDAALYSCVASNVAGTA 2278
Query: 778 FFEMKLKHYK---------------IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSD 822
E L+ Y + G ++ C V G P P + W KDG + K+
Sbjct: 2279 KKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLI-KAK 2337
Query: 823 HYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPS 882
I LD L + D G Y +A N G L V A P S
Sbjct: 2338 GVEI---LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA-------PPSII 2387
Query: 883 GHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDL 942
G+ ++P +++V E + C+ SG+P P +
Sbjct: 2388 GNH-----------------------------RSPENISVVEKNSVSLTCEASGIPLPSI 2418
Query: 943 SWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNS--FSLELV 1000
+W DG PV ++ ++L +G L + T DAG YTC+ N AG+ F L ++
Sbjct: 2419 TWFKDGWPVSLSNSVRIL---SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVL 2475
Query: 1001 VAAKEAHKPPVFI--EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVS 1058
V PP + L++ V + V L C V G P P+I W K+ + L
Sbjct: 2476 V-------PPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQED----E 2524
Query: 1059 MHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYIS 1104
H G L I G YT A + AG S + L+V++S
Sbjct: 2525 AHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVS 2570
Score = 122 bits (306), Expect = 2e-27
Identities = 194/912 (21%), Positives = 335/912 (36%), Gaps = 145/912 (15%)
Query: 264 ALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEG 323
+L AP V + V LEC G P P + W +G + + + G
Sbjct: 2005 SLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSG 2064
Query: 324 GDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASSTDSDSESLAFKSRAG 381
G + L A+ DTGRYTC+A N +G + V++ + + S+
Sbjct: 2065 GRILALTSAQI--SDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVE 2122
Query: 382 AMPQAQKKTTSVSLTIGSSSP---KTGVTTAVIQP-LSVPVQQVHSPTSYLCRPDGTT-- 435
+ Q+ + P K G++ + + L + QV Y C
Sbjct: 2123 LLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Query: 436 -------TAYFPPVF--TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
+ PP + EL V EG ++ L C G PP + W ++GS +
Sbjct: 2183 TEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSM 2242
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT------- 539
R+ R + ++ + IAE DA +++C A N G+A L V
Sbjct: 2243 GRV-----RILSGGRQL-QISIAEK--SDAALYSCVASNVAGTAKKEYNLQVYIRPTITN 2294
Query: 540 --SANTENCSYESMGESNNDHFQHFPPPP--------PILETSSLELASKKPSEIQQVNN 589
S TE S Q PPP P+++ +E+ + I Q+ N
Sbjct: 2295 SGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDE--GHILQLKN 2352
Query: 590 PELGLSRAALQMQFNAA----ERETNGVHPSRGVNGLINGKANSNKSLP---TPAVLLSP 642
+ + + + N A ++ VH + G N ++ N S+ + ++
Sbjct: 2353 IHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIG--NHRSPENISVVEKNSVSLTCEA 2410
Query: 643 TKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRL 702
+ P P + K G+P S + RI S + ++D + + +
Sbjct: 2411 SGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIF 2470
Query: 703 TYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDES-- 760
+ ++G ++ ++E + T E + + EI + + P+ E
Sbjct: 2471 GLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNP-----VPEITWHKDGQPLQEDEA 2525
Query: 761 ------GDEVQYGDVPVENG-------------MAPFFEMKL---------------KHY 786
G +Q +V V + + F + + +
Sbjct: 2526 HHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDV 2585
Query: 787 KIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDD 846
+ P + C P I WFKDG +P + I R L G +L + D+
Sbjct: 2586 TVILNSPTSLVCEAYSYPPATITWFKDG---TPLESNRNI-RILPGGRTLQILNAQEDNA 2641
Query: 847 GNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQE 906
G Y+ +A N G M++ + P P + + GD
Sbjct: 2642 GRYSCVATNEAGE-------MIKHYEVKVYIP------PIINK--------GD------- 2673
Query: 907 RFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGV 966
+ P +P ++ ++ ++C+ +P+ LSW DG+P++ D + + NG
Sbjct: 2674 -LWGPGL--SPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDD--HVNIAANG- 2727
Query: 967 HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTG------ 1020
H+L I+ D G YTC+A+N AG++ ++ + + + I + +TG
Sbjct: 2728 HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAK 2787
Query: 1021 -VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 1079
V P+ L C PPP + W K+ LT S+D+V + G L I A EDA
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLTWYKDGHPLT-SSDKVLILP---GGRVLQIPRAKVEDA 2843
Query: 1080 GWYTVSAKNEAG 1091
G YT A NEAG
Sbjct: 2844 GRYTCVAVNEAG 2855
Score = 109 bits (272), Expect = 2e-23
Identities = 93/318 (29%), Positives = 131/318 (41%), Gaps = 62/318 (19%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
PVT TC G P P I W K+ K+I SD + R L G L S D GNYT +
Sbjct: 3168 PVTLTCDATGIPPPTIAWLKNHKRIE-NSDSLEV-RILSGGSKLQIARSQHSDSGNYTCI 3225
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A+N +G+ L +Q P S +G
Sbjct: 3226 ASNMEGKAQKYYFLSIQV-------PPSVAG----------------------------- 3249
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
+ P D++V G+ + C +G+PTP + W DGKP+ ++ V NG I
Sbjct: 3250 -AEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 3308
Query: 973 PVTSRDAGIYTCIATNRAGQNS--FSLELVVA------AKEAHKPPVFIEKLQNTGVADG 1024
+TS D G YTC+ATN AG+ F+L + V EA K ++
Sbjct: 3309 ALTS-DTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT--------- 3358
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
+ +ECR G PPPQI W K L S+ + G + +++ A D YT
Sbjct: 3359 -SINIECRATGTPPPQINWLKNGLPLPLSS---HIRLLAAGQVIRIVR-AQVSDVAVYTC 3413
Query: 1085 SAKNEAGIVSCTARLDVY 1102
A N AG+ + L V+
Sbjct: 3414 VASNRAGVDNKHYNLQVF 3431
Score = 103 bits (257), Expect = 9e-22
Identities = 101/364 (27%), Positives = 147/364 (40%), Gaps = 80/364 (21%)
Query: 747 EIEYRLER--SPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNP 804
EI+Y ++ P E GDE Y V V N + C V G+P
Sbjct: 1722 EIKYEVDVLVPPAIEGGDETSYFIVMVNNLLE-------------------LDCHVTGSP 1762
Query: 805 KPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTG 864
P I W KDG+ I + + L+G L + + + G Y MAAN
Sbjct: 1763 PPTIMWLKDGQLIDERDGFKIL---LNGR-KLVIAQAQVSNTGLYRCMAANT-------- 1810
Query: 865 RLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPG--DLTV 922
+GD + + P +++ G + V
Sbjct: 1811 --------------------------------AGDHKKEFEVTVHVPPTIKSSGLSERVV 1838
Query: 923 QEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIY 982
+ K + C +G+P P ++W D +PV ++A L ++ L I DAG Y
Sbjct: 1839 VKYKPVALQCIANGIPNPSITWLKDDQPV--NTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 983 TCIATNRAGQNSFSLELVVAAKEAHKPPVFIE--KLQNTGVADGYPVRLECRVLGVPPPQ 1040
TC+ATN AG+ ++L V H+PP + K+ N V PV+LEC+ G P P
Sbjct: 1897 TCVATNAAGETQQHIQLHV-----HEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPV 1951
Query: 1041 IFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLD 1100
I W K+N L+ ST SM N G I + I+ A DAG Y A N AG L
Sbjct: 1952 ITWYKDNRLLSGST---SMTFLNRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQ 2007
Query: 1101 VYIS 1104
V+++
Sbjct: 2008 VHVA 2011
Score = 103 bits (256), Expect = 1e-21
Identities = 83/302 (27%), Positives = 126/302 (41%), Gaps = 47/302 (15%)
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
EG+PVT C+ +GNPKP + W K G+ IS S ++ D SL+ + ++ G Y
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGAD----GSLYVVSPGGEESGEY 1049
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 909
A N G +L V R R GD+ Q++
Sbjct: 1050 VCTATNTAGYAKRKVQLTVYV----------------------RPRVFGDQRGLSQDK-- 1085
Query: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
P +++V G+ + C+V LP P ++W + + + P S + S+
Sbjct: 1086 -------PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SM 1135
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
I + D+G+Y C+ATN AG + +++L V H PP ++ V G V +
Sbjct: 1136 KITETRTSDSGMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRVDI 1190
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
C G P P I W K ++ + + D L I AT DAG YT A N
Sbjct: 1191 PCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNI 1246
Query: 1090 AG 1091
AG
Sbjct: 1247 AG 1248
Score = 99.8 bits (247), Expect = 1e-20
Identities = 78/311 (25%), Positives = 126/311 (40%), Gaps = 56/311 (18%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
P+ C G P P I W K+G ++ ++ + + L + + +D G Y +
Sbjct: 4004 PILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLP----SGGLQISRAVREDAGTYMCV 4059
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A NP G +L VQ P PH++
Sbjct: 4060 AQNPAGTALGKIKLNVQV---------PPVISPHLK------------------------ 4086
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
+ + K + C+ GLP PD++W DG+ + +S + ++ + ++
Sbjct: 4087 ------EYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-VESIRQRVLSSGSLQIAFVQ 4139
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
P DAG YTC+A N AG +S S +L V H PP + V + L C
Sbjct: 4140 P---GDAGHYTCMAANVAGSSSTSTKLTV-----HVPPRIRSTEGHYTVNENSQAILPCV 4191
Query: 1033 VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGI 1092
G+P P I WKK+N L + + + Y L+++ ED+G+YT A N AG
Sbjct: 4192 ADGIPTPAINWKKDNVLLANLLGKYTAEP----YGELILENVVLEDSGFYTCVANNAAGE 4247
Query: 1093 VSCTARLDVYI 1103
+ T L V++
Sbjct: 4248 DTHTVSLTVHV 4258
Score = 97.1 bits (240), Expect = 8e-20
Identities = 91/322 (28%), Positives = 122/322 (37%), Gaps = 51/322 (15%)
Query: 784 KHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTL 843
KH K+ G V C G P P I W K G + +H+ + DGT S+ +T
Sbjct: 1178 KHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV--SNPDGTLSIDQ--ATP 1233
Query: 844 DDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEP 903
D G YT +A N G L HV+ P + N
Sbjct: 1234 SDAGIYTCVATNIAGTDETEITL-------------------HVQEPPTVEDLEPPYNTT 1274
Query: 904 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 963
QER C G P P + W +G+ + ++ +
Sbjct: 1275 FQERVANQRI---------------EFPCPAKGTPKPTIKWLHNGRELTGREPGISILED 1319
Query: 964 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQ--NTGV 1021
+ L+I VT D G Y C+A N AG L V H PPV +K Q N V
Sbjct: 1320 GTL--LVIASVTPYDNGEYICVAVNEAGTTERKYNLKV-----HVPPVIKDKEQVTNVSV 1372
Query: 1022 ADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGW 1081
L C V G P P I W K+N +T S+ ++ N+G I L + AT EDAG
Sbjct: 1373 LLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESS---TIQTVNNGKILKLFR-ATPEDAGR 1428
Query: 1082 YTVSAKNEAGIVSCTARLDVYI 1103
Y+ A N AG +DV +
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVLV 1450
Score = 95.9 bits (237), Expect = 2e-19
Identities = 88/322 (27%), Positives = 120/322 (37%), Gaps = 61/322 (18%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
+ G VT C V P P I W K+ + ISP S +T + S+ T + D G
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLP----SGSMKITETRTSDSG 1146
Query: 848 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 907
Y +A N G ++ QAV P
Sbjct: 1147 MYLCVATNIAGNVT-------QAVKLNVHVP----------------------------- 1170
Query: 908 FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
P + P L VQ G+ + C G P P ++W G + D H + N
Sbjct: 1171 ---PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV---SNPDG 1224
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV---AAKEAHKPP---VFIEKLQNTGV 1021
+L I+ T DAGIYTC+ATN AG + + L V E +PP F E++ N
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN--- 1281
Query: 1022 ADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGW 1081
+ C G P P I W LT +S+ +D L+I T D G
Sbjct: 1282 ---QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDG---TLLVIASVTPYDNGE 1335
Query: 1082 YTVSAKNEAGIVSCTARLDVYI 1103
Y A NEAG L V++
Sbjct: 1336 YICVAVNEAGTTERKYNLKVHV 1357
Score = 94.7 bits (234), Expect = 4e-19
Identities = 90/314 (28%), Positives = 122/314 (38%), Gaps = 56/314 (17%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
P++ C P P + W+KDG ++ SD I L G L + ++D G YT +
Sbjct: 2794 PISLYCETNAAPPPTLTWYKDGHPLT-SSDKVLI---LPGGRVLQIPRAKVEDAGRYTCV 2849
Query: 853 AANPQGRISCTG--RLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
A N G S R++V + + S
Sbjct: 2850 AVNEAGEDSLQYDVRVLVPPIIKGANS--------------------------------- 2876
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P ++TV K ++C SG P P SWQ DG+P+ D HK L NG L
Sbjct: 2877 ----DLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFL--SNG-RILQ 2929
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI-EKLQNTGVADGYPVRL 1029
I D G Y C+A N AG L V H PP I K +N V + L
Sbjct: 2930 ILNTQITDIGRYVCVAENTAGSAKKYFNLNV-----HVPPSVIGPKSENLTVVVNNFISL 2984
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
C V G PPP + W K + + +T+ + + G L I A D G YT A N+
Sbjct: 2985 TCEVSGFPPPDLSWLKNEQPIKLNTNTLIV----PGGRTLQIIRAKVSDGGEYTCIAINQ 3040
Query: 1090 AGIVSCTARLDVYI 1103
AG L VY+
Sbjct: 3041 AGESKKKFSLTVYV 3054
Score = 93.2 bits (230), Expect = 1e-18
Identities = 182/845 (21%), Positives = 291/845 (34%), Gaps = 158/845 (18%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V G V L C V P P + W E + + G + I E D+G
Sbjct: 1091 VLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMK---ITETRTSDSGM 1147
Query: 342 YTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSS 401
Y C+ATN +G+ T + ++ + + L + + T + + S
Sbjct: 1148 YLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKG 1207
Query: 402 PKTGVTTA---VIQP---LSVPVQQVHSPTSYLC---------RPDGTTTAYFPPVFTKE 446
T + V P LS+ Y C + T PP ++
Sbjct: 1208 GSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT-VED 1266
Query: 447 LQ---NTAVAE---GQVVVLECRVRGAPPLQVQWFRQGSEIQD-SPDFRILQKKPRSTAE 499
L+ NT E Q + C +G P ++W G E+ P IL
Sbjct: 1267 LEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISIL--------- 1317
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV----TSANTENCSYES--MGE 553
E+ LVIA P D G + C A N+ G+ L V + E + S + +
Sbjct: 1318 -EDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQ 1376
Query: 554 SNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGV 613
N + P PI+ + + S IQ VNN ++ ++ A E G
Sbjct: 1377 LTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKI--------LKLFRATPEDAGR 1428
Query: 614 HPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTAR--IASDE 671
+ + +N + N + P ++ FP + S +A +
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVLVPPTIIG-------------TNFPNEVSVVLNRDVALEC 1475
Query: 672 EIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEP-EEET 730
+++GT I +G+P + + LL D V +++ +
Sbjct: 1476 QVKGTPFPDIH-----------WFKDGKPLFLGDPNV--ELL--DRGQVLHLKNARRNDK 1520
Query: 731 ANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFE 790
+ VS+ + +I+ + P ++ G+V + + +KL+
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPP------SIKGGNVTTDISVLINSLIKLE------ 1568
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
C G P P I W+KDG+ I S I D LH + + D YT
Sbjct: 1569 -------CETRGLPMPAITWYKDGQPIMSSSQALYI----DKGQYLHIPRAQVSDSATYT 1617
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
AN G S H V P G+ P+ ++
Sbjct: 1618 CHVANVAG-------------------TAEKSFHVDVYVP---PMIEGNLATPLNKQVVI 1655
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
H L ++CK +G P+P L+W DG PV+ A+ + E G L
Sbjct: 1656 AHSL--------------TLECKAAGNPSPILTWLKDGVPVK---ANDNIRIEAGGKKLE 1698
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVV----AAKEAHKPPVFIEKLQNTGVADGYP 1026
I D G Y C+AT+ AG+ E+ V A + + FI + N
Sbjct: 1699 IMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNL------- 1751
Query: 1027 VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 1086
+ L+C V G PPP I W K+ + L D + + L+I A + G Y A
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQ-LIDERDGFKILLNGRK---LVIAQAQVSNTGLYRCMA 1807
Query: 1087 KNEAG 1091
N AG
Sbjct: 1808 ANTAG 1812
Score = 91.7 bits (226), Expect = 4e-18
Identities = 89/306 (29%), Positives = 120/306 (39%), Gaps = 50/306 (16%)
Query: 798 CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 857
C +G+P P+ W KDG+ + + DH+ L L + + D G Y +A N
Sbjct: 2894 CLSSGSPAPRNSWQKDGQPLL-EDDHHKF---LSNGRILQILNTQITDIGRYVCVAENTA 2949
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP 917
G L V P V P+S +
Sbjct: 2950 GSAKKYFNLNVHVP-------------PSVIGPKSEN----------------------- 2973
Query: 918 GDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSR 977
LTV + C+VSG P PDLSW + +P++ ++ L+ G II S
Sbjct: 2974 --LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNT--NTLIVPGGRTLQIIRAKVS- 3028
Query: 978 DAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVP 1037
D G YTCIA N+AG++ L V + K E L V +G V LEC VP
Sbjct: 3029 DGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDS-ESLSVVNVREGTSVSLECESNAVP 3087
Query: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 1097
PP I W K +T ST V + D L I+ A D G Y A N AG
Sbjct: 3088 PPVITWYKNGRMITEST-HVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNF 3143
Query: 1098 RLDVYI 1103
L+VY+
Sbjct: 3144 HLNVYV 3149
Score = 91.3 bits (225), Expect = 5e-18
Identities = 86/330 (26%), Positives = 127/330 (38%), Gaps = 57/330 (17%)
Query: 782 KLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTAS 841
+L + EG ++ C +G P P + W K G + +D R L G L + +
Sbjct: 2202 ELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVL--TDSMGRVRILSGGRQLQISIA 2259
Query: 842 TLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDEN 901
D Y+ +A+N G L V R +SG
Sbjct: 2260 EKSDAALYSCVASNVAGTAKKEYNLQVYI--------------------RPTITNSGSH- 2298
Query: 902 EPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLV 961
P ++ V GK ++C+V G+P P ++W DG P+ A + +
Sbjct: 2299 ---------------PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPL--IKAKGVEI 2341
Query: 962 RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI---EKLQN 1018
+ G H L ++ + D G Y C+A N AG +L V H PP I +N
Sbjct: 2342 LDEG-HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV-----HAPPSIIGNHRSPEN 2395
Query: 1019 TGVADGYPVRLECRVLGVPPPQIFWKKEN--ESLTHSTDRVSMHQDNHGYICLLIQGATK 1076
V + V L C G+P P I W K+ SL++S +S G L + T
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS------GGRMLRLMQTTM 2449
Query: 1077 EDAGWYTVSAKNEAGIVSCTARLDVYISRH 1106
EDAG YT +N AG L V + H
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVLVPPH 2479
Score = 87.8 bits (216), Expect = 5e-17
Identities = 80/317 (25%), Positives = 132/317 (41%), Gaps = 60/317 (18%)
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
+G + +C+ G P PK+ W + I D ++G L + +D G Y
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD------SVNGHSELVIERVSKEDSGTY 4326
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 909
A N G V+A+ G +V+ P P+ + +
Sbjct: 4327 VCTAENSVG--------FVKAI-----------GFVYVKEP------------PVFKGDY 4355
Query: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
++++ G + ++C+V G PTP + W G + + +H+ +R+ G SL
Sbjct: 4356 PSNWIEPLGGNAI-------LNCEVKGDPTPTIQWNRKGVDI--EISHR--IRQLGNGSL 4404
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
I + DAG YTC+ATN AG S+ L + PP+ + T + G + L
Sbjct: 4405 AIYGTVNEDAGDYTCVATNEAGVVERSMSLTL-----QSPPIITLEPVETVINAGGKIIL 4459
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
C+ G P P I W ++ S++ DRV++ +N YI A KED + A+N
Sbjct: 4460 NCQATGEPQPTITWSRQGHSISWD-DRVNVLSNNSLYIA----DAQKEDTSEFECVARNL 4514
Query: 1090 AGIVSCTARLDVYISRH 1106
G S R+ V + H
Sbjct: 4515 MG--SVLVRVPVIVQVH 4529
Score = 82.8 bits (203), Expect = 2e-15
Identities = 85/318 (26%), Positives = 122/318 (38%), Gaps = 54/318 (16%)
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
EG V+ C P P I W+K+G+ I+ +S H I D LH + + D G Y
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMIT-ESTHVEILADGQ---MLHIKKAEVSDTGQY 3128
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 909
A N GR + H +V P S G E E I E
Sbjct: 3129 VCRAINVAGR-------------------DDKNFHLNVYVPPSIE---GPEREVIVETIS 3166
Query: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
P + C +G+P P ++W + K + + ++ + G L
Sbjct: 3167 NP----------------VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGG-SKL 3209
Query: 970 IIEPVTSRDAGIYTCIATNRAG--QNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
I D+G YTCIA+N G Q + L + V A E + V G V
Sbjct: 3210 QIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGA-----EIPSDVSVLLGENV 3264
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHS-TDRVSMHQDNHGYICLLIQGATKEDAGWYTVSA 1086
L C G+P P I W K+ + + T+R+ + + L I GA D G YT A
Sbjct: 3265 ELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS---TLNIYGALTSDTGKYTCVA 3321
Query: 1087 KNEAGIVSCTARLDVYIS 1104
N AG L+VY++
Sbjct: 3322 TNPAGEEDRIFNLNVYVT 3339
Score = 82.4 bits (202), Expect = 2e-15
Identities = 85/339 (25%), Positives = 129/339 (38%), Gaps = 53/339 (15%)
Query: 767 GDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFK-DGKQISPKSDHYT 825
G + ++ G P F + + G VT C V G P+P I W + D I + +
Sbjct: 783 GKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVS 842
Query: 826 IQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHP 885
L T +L D G Y A N G+I + V +
Sbjct: 843 SISQLR-TGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGL-------------- 887
Query: 886 HVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKV-SGLPTPDLSW 944
P +P V EG+ + C + +G P P+ W
Sbjct: 888 -----------------------VAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW 924
Query: 945 QLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
+ + + + VR +G SL IE V +D G YTC+A+N AG N+ + +VV
Sbjct: 925 IKNSAMLLQNPY--ITVRSDG--SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV--- 977
Query: 1005 EAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNH 1064
H P Q +G PV L C+ G P P + W K+ E ++ S+ + S D
Sbjct: 978 --HVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS 1035
Query: 1065 GYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
Y+ E++G Y +A N AG +L VY+
Sbjct: 1036 LYVV----SPGGEESGEYVCTATNTAGYAKRKVQLTVYV 1070
Score = 82.0 bits (201), Expect = 3e-15
Identities = 83/322 (25%), Positives = 124/322 (38%), Gaps = 60/322 (18%)
Query: 784 KHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTL 843
K+ G V+ C G PKPKI W + I + + DGT + A
Sbjct: 619 KNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGS---HRYRMTSDGTLFIKNAAPK- 674
Query: 844 DDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEP 903
D G Y +A+N G + + S ++ P+ S
Sbjct: 675 -DAGIYGCLASNSAG------------------TDKQNSTLRYIEAPKLMVVQS------ 709
Query: 904 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 963
L A GD+TV M+CK SG+P P + W +RP + L+ +
Sbjct: 710 --------ELLVALGDITV-------MECKTSGIPPPQVKWFKGDLELRPST---FLIID 751
Query: 964 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVAD 1023
+ L I+ DAG YTC+A N AG+ + + L V + PPVFI++ + +
Sbjct: 752 PLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS-----PPVFIQEPADVSMEI 806
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENE----SLTHSTDRVSMHQDNHGYICLLIQGATKEDA 1079
G V L C V G P P I W++ + S S +S + L I D
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG----ALFILNLWASDK 862
Query: 1080 GWYTVSAKNEAGIVSCTARLDV 1101
G Y A+N+ G + + V
Sbjct: 863 GTYICEAENQFGKIQSETTVTV 884
Score = 79.7 bits (195), Expect = 1e-14
Identities = 73/309 (23%), Positives = 125/309 (40%), Gaps = 56/309 (18%)
Query: 798 CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 857
C V G P P I W+KD Q++ S T T+++ + A P+
Sbjct: 1382 CEVEGTPSPIIMWYKDNVQVTESS-----------------TIQTVNNGKILKLFRATPE 1424
Query: 858 --GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQ 915
GR SC +A+N G S + + + + +F
Sbjct: 1425 DAGRYSC------KAINIAGTSQKY-----------------FNIDVLVPPTIIGTNF-- 1459
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV-RPDSAHKMLVRENGVHSLIIEPV 974
P +++V + ++C+V G P PD+ W DGKP+ D ++L R +H ++
Sbjct: 1460 -PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLH---LKNA 1515
Query: 975 TSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVL 1034
D G Y C +N AG+ + ++L + + K + V ++LEC
Sbjct: 1516 RRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG---NVTTDISVLINSLIKLECETR 1572
Query: 1035 GVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 1094
G+P P I W K+ + + S+ + + + + L I A D+ YT N AG
Sbjct: 1573 GLPMPAITWYKDGQPIMSSSQALYIDKGQY----LHIPRAQVSDSATYTCHVANVAGTAE 1628
Query: 1095 CTARLDVYI 1103
+ +DVY+
Sbjct: 1629 KSFHVDVYV 1637
Score = 77.8 bits (190), Expect = 5e-14
Identities = 73/301 (24%), Positives = 126/301 (41%), Gaps = 54/301 (17%)
Query: 794 VTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMA 853
++ TC V+G P P + W K+ + I ++ + G +L + + D G YT +A
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP----GGRTLQIIRAKVSDGGEYTCIA 3037
Query: 854 ANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHF 913
+NQ G S + S +V P + DS
Sbjct: 3038 -----------------INQAGESKKKFSLTVYVP-PSIKDHDS---------------- 3063
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEP 973
++ + V+EG ++C+ + +P P ++W +G+ + + ++L +H I+
Sbjct: 3064 -ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLH---IKK 3119
Query: 974 VTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP---VFIEKLQNTGVADGYPVRLE 1030
D G Y C A N AG++ + L V + + P V +E + N PV L
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISN-------PVTLT 3172
Query: 1031 CRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1090
C G+PPP I W K ++ + +S D + + + G L I + D+G YT A N
Sbjct: 3173 CDATGIPPPTIAWLKNHKRIENS-DSLEVRILSGG-SKLQIARSQHSDSGNYTCIASNME 3230
Query: 1091 G 1091
G
Sbjct: 3231 G 3231
Score = 77.4 bits (189), Expect = 7e-14
Identities = 79/315 (25%), Positives = 124/315 (39%), Gaps = 59/315 (18%)
Query: 794 VTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMA 853
V C+V G P P I+WFKDGK + + + LD LH + +D G Y
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPLFLGDPNVEL---LDRGQVLHLKNARRNDKGRYQCTV 1527
Query: 854 ANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHF 913
+N G+ + +L + P S G
Sbjct: 1528 SNAAGKQAKDIKLTIYI-------PPSIKGG----------------------------- 1551
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEP 973
D++V L +++C+ GLP P ++W DG+P+ S+ + L + G + L I
Sbjct: 1552 -NVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIM--SSSQALYIDKGQY-LHIPR 1607
Query: 974 VTSRDAGIYTCIATNRAG--QNSFSLELVVAAKEAHKPPVFIEKLQ---NTGVADGYPVR 1028
D+ YTC N AG + SF +++ V PP+ L N V + +
Sbjct: 1608 AQVSDSATYTCHVANVAGTAEKSFHVDVYV-------PPMIEGNLATPLNKQVVIAHSLT 1660
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
LEC+ G P P + W K+ + + D + + G L I A + D G Y A +
Sbjct: 1661 LECKAAGNPSPILTWLKDGVPV-KANDNIRIEA---GGKKLEIMSAQEIDRGQYICVATS 1716
Query: 1089 EAGIVSCTARLDVYI 1103
AG +DV +
Sbjct: 1717 VAGEKEIKYEVDVLV 1731
Score = 75.9 bits (185), Expect = 2e-13
Identities = 75/292 (25%), Positives = 116/292 (39%), Gaps = 41/292 (14%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P+ ++Q GS V + C TG P P++ W + + ++ +G TL
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG----TLF 667
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEV-FIEGASSTDSDSESLA-------FKSRAGA 382
I A D G Y CLA+N +G+D ++ + +IE SE L + +
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSG 727
Query: 383 MPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPL----SVPVQQVHSPTSYLC-------RP 431
+P Q K L + S T +I PL + Q Y C R
Sbjct: 728 IPPPQVKWFKGDLELRPS------TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRA 781
Query: 432 DGTTTAYF--PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRI 489
G T PPVF +E + ++ G V L C V+G P ++W R + + P F
Sbjct: 782 TGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRR----LDNMPIF-- 835
Query: 490 LQKKPRSTAEPEEICT--LVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT 539
+P S + ++ T L I + D G + C A N +G S + VT
Sbjct: 836 --SRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVT 885
Score = 69.3 bits (168), Expect = 2e-11
Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 12/181 (6%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P +Q P ++TV G+ + C + +L+WQ + + VR A +R SL
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR--LAEPARIRTLANLSLE 577
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 1030
++ V DAG Y C+ ++ G ++ S+ L V +PP +N G V +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----QEPPKVTVMPKNQSFTGGSEVSIM 632
Query: 1031 CRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1090
C G P P+I W N+ + R M D L I+ A +DAG Y A N A
Sbjct: 633 CSATGYPKPKIAW-TVNDMFIVGSHRYRMTSDG----TLFIKNAAPKDAGIYGCLASNSA 687
Query: 1091 G 1091
G
Sbjct: 688 G 688
Score = 67.8 bits (164), Expect = 5e-11
Identities = 68/278 (24%), Positives = 109/278 (39%), Gaps = 41/278 (14%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE----- 336
V + + + C +G P P + W G L GD + ++ + A E
Sbjct: 3908 VTKHAPAVITCTASGVPFPSIHWTKNGIRL---------LPRGDGYRILSSGAIEILATQ 3958
Query: 337 -DDTGRYTCLATNPSGSDTTSAEVFI-EGASSTDSDSESLAFKSRAGAMPQAQKKTTSVS 394
+ GRYTC+A N +GS + + E SE + +P T S
Sbjct: 3959 LNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPF 4018
Query: 395 LTI---GSSSPKTGVTTAVIQPLSVPVQQV--HSPTSYLC---RPDGTT------TAYFP 440
+T G + +G AV+ + + + +Y+C P GT P
Sbjct: 4019 ITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVP 4078
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
PV + L+ +A + + L C G PP + W + G I +S R+L
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG------- 4131
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+L IA P DAG +TC A N GS++++ +L V
Sbjct: 4132 ----SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 67.4 bits (163), Expect = 7e-11
Identities = 67/269 (24%), Positives = 104/269 (38%), Gaps = 35/269 (13%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHN--TPDIQIHCEGGDLHTLIIAEAFEDDTGRY 342
G V L C G PTP ++W +GK + + T I++ G TL I A DTG+Y
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS---TLNIYGALTSDTGKY 3317
Query: 343 TCLATNPSGSDTT--SAEVFIEGASSTDSD---------SESLAFKSRAGAMPQAQKKTT 391
TC+ATNP+G + + V++ + D S+ + RA P Q
Sbjct: 3318 TCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWL 3377
Query: 392 SVSLTIG-SSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF------PPVFT 444
L + SS + VI+ + V V T G ++ PP
Sbjct: 3378 KNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMD 3437
Query: 445 KEL--QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEE 502
+ + V +G + C G P + W R G + + +
Sbjct: 3438 NSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV--------STHGM 3489
Query: 503 ICTLVIAETFPEDAGIFTCSARNDYGSAT 531
+ L+ AET ED+G +TC A N+ G +
Sbjct: 3490 VLQLLKAET--EDSGKYTCIASNEAGEVS 3516
Score = 67.0 bits (162), Expect = 9e-11
Identities = 62/194 (31%), Positives = 91/194 (46%), Gaps = 19/194 (9%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P P + + G + C +G P P ++W ++ + +H+ + +G +L
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIV--GSHRYRMTSDG--TLF 667
Query: 971 IEPVTSRDAGIYTCIATNRAG---QNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
I+ +DAGIY C+A+N AG QNS +L + EA K V +L VA G
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNS-TLRYI----EAPKLMVVQSELL---VALGDIT 719
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 1087
+EC+ G+PPPQ+ W K + L ST + + L IQ DAG YT A
Sbjct: 720 VMECKTSGIPPPQVKWFKGDLELRPSTFLII----DPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 1088 NEAGIVSCTARLDV 1101
NEAG + LDV
Sbjct: 776 NEAGRATGKITLDV 789
Score = 67.0 bits (162), Expect = 9e-11
Identities = 71/297 (23%), Positives = 114/297 (38%), Gaps = 34/297 (11%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDD 338
+++V + LEC+ GNP+P + W +G + +I+I G L I A E D
Sbjct: 1650 NKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLE---IMSAQEID 1706
Query: 339 TGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ------AQKKTTS 392
G+Y C+AT+ +G EV + + + E+ F + + T
Sbjct: 1707 RGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSPPPTI 1766
Query: 393 VSLTIGSSSPKTGVTTAVI--QPLSVPVQQVHSPTSYLCRPDGT---------TTAYFPP 441
+ L G + ++ + L + QV + Y C T T + PP
Sbjct: 1767 MWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Query: 442 -VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
+ + L V + + V L+C G P + W + + + +Q R
Sbjct: 1827 TIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR----- 1881
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNND 557
L IA+T EDAG +TC A N G QL V E S E G+ N+
Sbjct: 1882 ----VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV----HEPPSLEDAGKMLNE 1930
Score = 67.0 bits (162), Expect = 9e-11
Identities = 73/288 (25%), Positives = 114/288 (39%), Gaps = 42/288 (14%)
Query: 276 KLRSQE----VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
++RS E V E S+ L C G PTP + W + L N G+L I+
Sbjct: 4170 RIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGEL---IL 4226
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD--------SDSESLAFKSRAGAM 383
+D+G YTC+A N +G DT + + + + + E L +A +
Sbjct: 4227 ENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGI 4286
Query: 384 PQAQKKTTSVSLTIGSSSPKT-GVTTAVIQPLSVPVQQVHSPTSYLCRPD---------G 433
P + T + I + G + VI+ +S +Y+C + G
Sbjct: 4287 PLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSK-----EDSGTYVCTAENSVGFVKAIG 4341
Query: 434 TTTAYFPPVFTKELQNTAVAE-GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQK 492
PPVF + + + G +L C V+G P +QW R+G +I+ S R L
Sbjct: 4342 FVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGN 4401
Query: 493 KPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
+L I T EDAG +TC A N+ G + L + S
Sbjct: 4402 G-----------SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Score = 65.9 bits (159), Expect = 2e-10
Identities = 64/284 (22%), Positives = 103/284 (36%), Gaps = 33/284 (11%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT-L 329
P F + + +G ++ L C+ TG P P++ W N I H + + H+ L
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW------TFNNNIIPAHFDSVNGHSEL 4313
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSES-----------LAFKS 378
+I ++D+G Y C A N G V+++ D S L +
Sbjct: 4314 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEV 4373
Query: 379 RAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPL----SVPVQQVHSPTSYLCRPDGT 434
+ P Q V + I + G + I + V + + + +
Sbjct: 4374 KGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMS 4433
Query: 435 TTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKP 494
T PP+ T E T + G ++L C+ G P + W RQG I +L
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNN- 4492
Query: 495 RSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+L IA+ ED F C ARN GS ++V
Sbjct: 4493 ----------SLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 65.5 bits (158), Expect = 3e-10
Identities = 67/294 (22%), Positives = 114/294 (38%), Gaps = 48/294 (16%)
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
+H P P+ + + +V G RV + C G P P + W G + D + H
Sbjct: 1167 VHVP--PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTM--LVDGEHHVSNP 1222
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDS-------------DS 371
D TL I +A D G YTC+ATN +G+D T + ++ + + +
Sbjct: 1223 D-GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 372 ESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGV----TTAVIQPLSVPVQQVHSPTSY 427
+ + F A P+ K + P + T VI ++ + Y
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVT-----PYDNGEY 1336
Query: 428 LC---RPDGTT------TAYFPPVF--TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFR 476
+C GTT + PPV +++ N +V Q+ L C V G P + W++
Sbjct: 1337 ICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYK 1396
Query: 477 QGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSA 530
++ +S + + L + PEDAG ++C A N G++
Sbjct: 1397 DNVQVTESSTIQTVNNGK----------ILKLFRATPEDAGRYSCKAINIAGTS 1440
Score = 65.1 bits (157), Expect = 4e-10
Identities = 79/313 (25%), Positives = 114/313 (36%), Gaps = 42/313 (13%)
Query: 251 VPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVA--EGSRVYLECRVTGNPTPRVRWFCEG 308
V NR H L A P + ++E+ +GS + C G P P + W +G
Sbjct: 3414 VASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDG 3473
Query: 309 KELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDT------TSAEVFIE 362
+ L + + G L L +A +D+G+YTC+A+N +G + I
Sbjct: 3474 QPLGLDAHLTVSTHGMVLQLL---KAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHIN 3530
Query: 363 GASSTDSDS----ESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTG--VTTAVIQPLSV 416
G+ + S L A +P A K T + G P+T T + L +
Sbjct: 3531 GSEEHEEISVIVNNPLELTCIASGIP-APKMTW---MKDGRPLPQTDQVQTLGGGEVLRI 3586
Query: 417 PVQQVHSPTSYLC---RPDG------TTTAYFPP--VFTKELQNTAVAEGQVVVLECRVR 465
QV Y C P G + PP T E ++ V + V LEC+
Sbjct: 3587 STAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSD 3646
Query: 466 GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARN 525
PP + W R G +Q +P RIL L I D +TC A N
Sbjct: 3647 AVPPPVITWLRNGERLQATPRVRILSGGR----------YLQINNADLGDTANYTCVASN 3696
Query: 526 DYGSATSTAQLVV 538
G T L V
Sbjct: 3697 IAGKTTREFILTV 3709
Score = 63.5 bits (153), Expect = 1e-09
Identities = 74/281 (26%), Positives = 110/281 (39%), Gaps = 38/281 (13%)
Query: 282 VAEGSRVYLECRV-TGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
V EG ++ L C + GNP P RW L P I + +G +L I D G
Sbjct: 901 VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG----SLHIERVQLQDGG 956
Query: 341 RYTCLATNPSGSD--TTSAEVFI--------EGASSTDSDSESLAFKSRAGAMPQA--QK 388
YTC+A+N +G++ TTS V + + S+ + +L K+ P K
Sbjct: 957 EYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSK 1016
Query: 389 KTTSVSLTIGSSSPKTGVTTAVIQP----LSVPVQQVHSPTSYLCRPDGTTTAYFPPVFT 444
K +S + S + V+ P V + Y R T P VF
Sbjct: 1017 KGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFG 1076
Query: 445 KEL-------QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
+ +V G+ V L C V+ PP + W ++ I SP PR T
Sbjct: 1077 DQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLI--SP------FSPRHT 1128
Query: 498 AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P ++ I ET D+G++ C A N G+ T +L V
Sbjct: 1129 FLPSG--SMKITETRTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 63.5 bits (153), Expect = 1e-09
Identities = 66/275 (24%), Positives = 103/275 (37%), Gaps = 33/275 (12%)
Query: 275 QKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEA 334
+ L V EG+ V LEC P P + W+ G+ + + ++I +G LH I +A
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLH---IKKA 3120
Query: 335 FEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVS 394
DTG+Y C A N +G D + + + S + + ++ + + T
Sbjct: 3121 EVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPP 3180
Query: 395 LTIG----------SSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---RPDGTTTAYF-- 439
TI S S + + + + L + Q +Y C +G Y+
Sbjct: 3181 PTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQKYYFL 3239
Query: 440 -----PPVFTKEL-QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKK 493
P V E+ + +V G+ V L C G P +QW + G I RI
Sbjct: 3240 SIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSA 3299
Query: 494 PRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYG 528
S TL I D G +TC A N G
Sbjct: 3300 NGS--------TLNIYGALTSDTGKYTCVATNPAG 3326
Score = 63.2 bits (152), Expect = 1e-09
Identities = 88/422 (20%), Positives = 151/422 (35%), Gaps = 72/422 (17%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDD 338
+++V + + L C P P + W+ +G L ++ + I GG L I A +D
Sbjct: 2786 AKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLI-LPGG--RVLQIPRAKVED 2842
Query: 339 TGRYTCLATNPSGSDTTSAEV------FIEGASSTDSDSESLAFKSRAGAMPQAQKKTTS 392
GRYTC+A N +G D+ +V I+GA+S + ++ K
Sbjct: 2843 AGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVL----------VNKSALI 2892
Query: 393 VSLTIGSSSPKTG-----------------VTTAVIQPLSVPVQQVHSPTSYLCRPDGTT 435
L+ GS +P+ ++Q L+ + + G+
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSA 2952
Query: 436 TAYF-------PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
YF P V + +N V + L C V G PP + W + I+ + +
Sbjct: 2953 KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTL 3012
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV------TSAN 542
I+ TL I D G +TC A N G + L V +
Sbjct: 3013 IVPGGR----------TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHD 3062
Query: 543 TENCSYESMGESNNDHFQ---HFPPPPPI-------LETSSLELASKKPSEIQQVNNPEL 592
+E+ S ++ E + + + PPP I + T S + ++ + E+
Sbjct: 3063 SESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEV 3122
Query: 593 GLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANS--NKSLPTPAVL-LSPTKEPPPL 649
+ + N A R+ H + V I G +++ P L T PPP
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPT 3182
Query: 650 LA 651
+A
Sbjct: 3183 IA 3184
Score = 60.8 bits (146), Expect = 7e-09
Identities = 73/294 (24%), Positives = 113/294 (38%), Gaps = 58/294 (19%)
Query: 284 EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYT 343
EG V L C+ +GNP P V W +G EL +T + G D +++ E+ +G Y
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSA-GADGSLYVVSPGGEE-SGEYV 1050
Query: 344 CLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGS---- 399
C ATN +G ++ + D L+ Q K +S+ G
Sbjct: 1051 CTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS-----------QDKPVEISVLAGEEVTL 1099
Query: 400 -----SSPKTGVT----TAVIQPLS----------VPVQQVHSPTS--YLCRPD---GTT 435
S P +T T +I P S + + + + S YLC G
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 436 T------AYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRI 489
T + PP + ++ V GQ V + C +G P + W + GS + + +
Sbjct: 1160 TQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHV 1219
Query: 490 LQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT 543
+ P+ TL I + P DAGI+TC A N G+ + L V T
Sbjct: 1220 --------SNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT 1263
Score = 60.5 bits (145), Expect = 9e-09
Identities = 81/314 (25%), Positives = 115/314 (36%), Gaps = 54/314 (17%)
Query: 249 LAVPHNRKSHPQPHSALHFPAAPRFI-QKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCE 307
+ V N + + L+ P I K + V + + L C V+G P P + W
Sbjct: 2942 VCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKN 3001
Query: 308 GKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTT--SAEVFIEGAS 365
+ + + I GG TL I A D G YTC+A N +G S V++ S
Sbjct: 3002 EQPIKLNTNTLI-VPGG--RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP-PS 3057
Query: 366 STDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTT----------------- 408
D DSESL+ + ++ TSVSL S++ V T
Sbjct: 3058 IKDHDSESLSVVN--------VREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL 3109
Query: 409 AVIQPLSVPVQQVHSPTSYLCRPDGTT---------TAYFPPVFTKELQNTAVAE-GQVV 458
A Q L + +V Y+CR Y PP + V V
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 459 VLECRVRGAPPLQVQWFRQGSEIQ--DSPDFRILQKKPRSTAEPEEICTLVIAETFPEDA 516
L C G PP + W + I+ DS + RIL + L IA + D+
Sbjct: 3170 TLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSK----------LQIARSQHSDS 3219
Query: 517 GIFTCSARNDYGSA 530
G +TC A N G A
Sbjct: 3220 GNYTCIASNMEGKA 3233
Score = 59.3 bits (142), Expect = 2e-08
Identities = 63/302 (20%), Positives = 103/302 (34%), Gaps = 27/302 (8%)
Query: 251 VPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKE 310
V N H LH P + V + + L C TG P+P + W EG
Sbjct: 3968 VARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGIN 4027
Query: 311 LHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD-- 368
++ + G L I+ A +D G Y C+A NP+G+ ++ ++
Sbjct: 4028 VNTSGRNHAVLPSGGLQ---ISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPH 4084
Query: 369 ------SDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVH 422
+ + + A +P I S + +++ +Q V
Sbjct: 4085 LKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAG 4144
Query: 423 SPTSYLCRPDGTT------TAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFR 476
T G++ T + PP + V E +L C G P + W +
Sbjct: 4145 HYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKK 4204
Query: 477 QGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL 536
+ + + TAEP L++ ED+G +TC A N G T T L
Sbjct: 4205 D--------NVLLANLLGKYTAEP--YGELILENVVLEDSGFYTCVANNAAGEDTHTVSL 4254
Query: 537 VV 538
V
Sbjct: 4255 TV 4256
Score = 57.8 bits (138), Expect = 6e-08
Identities = 67/294 (22%), Positives = 101/294 (34%), Gaps = 54/294 (18%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
PR I LR+++V LEC+ P P + W G+ L TP ++I G L
Sbjct: 3628 PRDITVLRNRQVT------LECKSDAVPPPVITWLRNGERLQATPRVRILSGG---RYLQ 3678
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
I A DT YTC+A+N +G T + + + +SL K T
Sbjct: 3679 INNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVI--------LLNKST 3730
Query: 391 TSVSLTIGSSSP-----KTGVTTA-------VIQPLSVPVQQVHSPTS--YLCRPDGTT- 435
+ G +P K G A +++ + +Q H + YLC
Sbjct: 3731 VLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAG 3790
Query: 436 --------TAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEI---QDS 484
+ PP N V L C G P + W + G + Q+
Sbjct: 3791 TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQ 3850
Query: 485 PDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+R+L +LVI +D + C+ N G T L V
Sbjct: 3851 NSYRLLSSG-----------SLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV 3893
Score = 57.4 bits (137), Expect = 7e-08
Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 55/284 (19%)
Query: 286 SRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCL 345
S + LEC G P P + W+ +G+ + ++ +G LH I A D+ YTC
Sbjct: 1563 SLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLH---IPRAQVSDSATYTCH 1619
Query: 346 ATNPSGSDTTSAEV------FIEGASSTDSDSE-----SLAFKSRAGAMPQ--------- 385
N +G+ S V IEG +T + + SL + +A P
Sbjct: 1620 VANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDG 1679
Query: 386 -AQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPV-------QQVHSPTSYLCRP---DGT 434
K ++ + G + + + + V +++ L P G
Sbjct: 1680 VPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGD 1739
Query: 435 TTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKP 494
T+YF V ++ L+C V G+PP + W + G I + F+IL
Sbjct: 1740 ETSYF-----------IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGR 1788
Query: 495 RSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ LVIA+ + G++ C A N G ++ V
Sbjct: 1789 K----------LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV 1822
Score = 56.2 bits (134), Expect = 2e-07
Identities = 68/307 (22%), Positives = 119/307 (38%), Gaps = 36/307 (11%)
Query: 254 NRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHN 313
N + +S L + AP+ + VA G +EC+ +G P P+V+WF EL
Sbjct: 685 NSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRP 744
Query: 314 TPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGS-------DTTSAEVFIEGASS 366
+ + I L L I E + D G YTC+A N +G D S VFI+ +
Sbjct: 745 STFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPAD 801
Query: 367 TDSD-SESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT 425
+ ++ P+ K + S P + + + ++ ++ + + +
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 426 --SYLCRPDG-----------TTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPL-Q 471
+Y+C + T T P+ V EGQ + L C + P+ +
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPE 921
Query: 472 VQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSAT 531
+W + + + +P + RS +L I +D G +TC A N G+
Sbjct: 922 RRWIKNSAMLLQNPYITV-----RSDG------SLHIERVQLQDGGEYTCVASNVAGTNN 970
Query: 532 STAQLVV 538
T +VV
Sbjct: 971 KTTSVVV 977
Score = 55.5 bits (132), Expect = 3e-07
Identities = 68/294 (23%), Positives = 108/294 (36%), Gaps = 46/294 (15%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P IQ + V G R L C + + W +++ +I +L
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN--LSLE 577
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE----------GASSTDSDSESLAFKSRA 380
+ +D G Y C+ ++ GS S + ++ S T S+ +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATG 637
Query: 381 GAMPQAQ--------------KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTS 426
P+ + T+ +L I +++PK + S + +S
Sbjct: 638 YPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLR 697
Query: 427 YLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
Y+ P V EL VA G + V+EC+ G PP QV+WF+ E++ S
Sbjct: 698 YIEAPKLM-------VVQSEL---LVALGDITVMECKTSGIPPPQVKWFKGDLELRPS-T 746
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
F I+ + L I ET DAG +TC A N+ G AT L V S
Sbjct: 747 FLIIDPL---------LGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGS 791
Score = 55.1 bits (131), Expect = 4e-07
Identities = 61/273 (22%), Positives = 100/273 (36%), Gaps = 36/273 (13%)
Query: 277 LRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTP-DIQIHCEGGDLHTLIIAEAF 335
L + V + V L+C G P P + W + + ++ +++I G L IA+
Sbjct: 1833 LSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSG---RVLQIAKTL 1889
Query: 336 EDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSD----------SESLAFKSRAGAMPQ 385
+D GRYTC+ATN +G ++ + S + S + + +A P
Sbjct: 1890 LEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPV 1949
Query: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---RPDGTTTAYF--- 439
+ + S+ T + Q + + Q+ Y C G T ++
Sbjct: 1950 PVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGATELFYSLQ 2007
Query: 440 ---PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQD-SPDFRILQKKPR 495
P + AV V LEC RG P + W + GS + S ++L
Sbjct: 2008 VHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVL----- 2062
Query: 496 STAEPEEICTLVIAETFPEDAGIFTCSARNDYG 528
I L A+ D G +TC A N G
Sbjct: 2063 ---SGGRILALTSAQI--SDTGRYTCVAVNAAG 2090
Score = 53.5 bits (127), Expect = 1e-06
Identities = 72/328 (21%), Positives = 108/328 (32%), Gaps = 52/328 (15%)
Query: 244 QDNQDL------AVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGN 297
Q+ QDL V N L + P FIQ+ + GS V L C V G
Sbjct: 760 QETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGY 819
Query: 298 PTPRVRWFCEGKELHNTPDIQIHCEGGDLH-----TLIIAEAFEDDTGRYTCLATNPSGS 352
P P ++W + L N P + L I + D G Y C A N G
Sbjct: 820 PEPTIKW----RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGK 875
Query: 353 DTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTG------- 405
+ V + G + + + + Q+ T +L G+ P+
Sbjct: 876 IQSETTVTVTGLV-----APLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAM 930
Query: 406 ------VTTAVIQPLSVPVQQVHSPTSYLC---------RPDGTTTAYFPPVFTKELQNT 450
+T L + Q+ Y C + + P Q
Sbjct: 931 LLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQIL 990
Query: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
+ EG V L C+ G P V W ++G I S K + A+ +L +
Sbjct: 991 STIEGIPVTLPCKASGNPKPSVIWSKKGELISTS------SAKFSAGADG----SLYVVS 1040
Query: 511 TFPEDAGIFTCSARNDYGSATSTAQLVV 538
E++G + C+A N G A QL V
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 43.9 bits (102), Expect = 8e-04
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTC 344
G ++ L C+ TG P P + W +G + + + ++L IA+A ++DT + C
Sbjct: 4454 GGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN----NSLYIADAQKEDTSEFEC 4509
Query: 345 LATNPSGSDTTSAEVFIE 362
+A N GS V ++
Sbjct: 4510 VARNLMGSVLVRVPVIVQ 4527
Score = 39.3 bits (90), Expect = 0.021
Identities = 40/173 (23%), Positives = 67/173 (38%), Gaps = 12/173 (6%)
Query: 929 RMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATN 988
++ C V L LS+ +G + D ++E+ +L I VT D G Y CIA +
Sbjct: 448 QIPCSVDSLLPFTLSFVRNGVTLGVDQ----YLKESASVNLDIAKVTLSDEGFYECIAVS 503
Query: 989 RAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENE 1048
AG V+ +PP I+ N V G L C ++ + W++ +
Sbjct: 504 SAGTGRAQTFFDVS-----EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDR 558
Query: 1049 SLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
+ + N + L ++ DAG Y +E G + + L V
Sbjct: 559 DVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV 608
Score = 30.4 bits (67), Expect = 9.7
Identities = 25/104 (24%), Positives = 39/104 (37%), Gaps = 19/104 (18%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP + N V G+ VL C + A + W R +++ AE
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR--------------LAE 564
Query: 500 PEEICTLV-----IAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P I TL + DAG + C ++ GS+ ++ L V
Sbjct: 565 PARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV 608
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 125 bits (313), Expect = 3e-28
Identities = 196/871 (22%), Positives = 315/871 (36%), Gaps = 175/871 (20%)
Query: 286 SRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCL 345
S + LEC P P +RW+ +G+ + + +Q+ EG L I D+GRY C+
Sbjct: 1464 STLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEG---RLLQIQPTQVSDSGRYLCV 1520
Query: 346 ATNPSGSDTTSAEVFIE--------GASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTI 397
ATN +G D V I+ G S + S ++R G + + +
Sbjct: 1521 ATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 1580
Query: 398 GSSSP---------------KTGVTTAVIQP---LSVPVQQVHSPTSYLCRPDGTT---- 435
++ G +V+Q L +P+ + + Y C+
Sbjct: 1581 CDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDW 1640
Query: 436 -----TAYFPPVF---TKEL-QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
PPV T+EL + V V L+C G P + W + G SP
Sbjct: 1641 LHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPR 1700
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL-VVTSANTEN 545
++L+ + ++ T +A DA + C A N GSA L V
Sbjct: 1701 LQVLED-----GQVLQVSTAEVA-----DAASYMCVAENQAGSAEKLFTLRVQVPPRIAG 1750
Query: 546 CSYESMGESNNDHFQ-----HFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQ 600
E + N H P P E+ K S+ + E+ L
Sbjct: 1751 LDLEQVTAILNSSVSLPCDVHAHPNP--------EVTWYKDSQALSLGE-EVFLLPGTHT 1801
Query: 601 MQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKK 660
+Q A +G++ +N A ++ L +VL+ P P
Sbjct: 1802 LQLGRARLSDSGMYTCEALNA-----AGRDQKLVQLSVLVPPAFRQAP------------ 1844
Query: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATV 720
+G +DAV+ + K + +P +T+ + +L + +
Sbjct: 1845 -------------RGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL 1891
Query: 721 FNIQEPEEETANQEYK-VSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFF 779
Q E + A K + SC+ +S + +G+ V+ + V+ + P F
Sbjct: 1892 RGGQRLEIQEAQVSDKGLYSCK---VSNV-----------AGEAVRTFTLTVQ--VPPTF 1935
Query: 780 EM-KLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
E K + G P+ TC V+G P P + W KD + + H + R G L
Sbjct: 1936 ENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRG--GRLQLSR 1993
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
G YT +A N Q + V AV + PR RS
Sbjct: 1994 LQPA--QAGTYTCVAENTQAEAR---KDFVVAV---------------LVAPRIRSSGVA 2033
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD-SAH 957
E+ V EG+ R+DC+ G P PD++W DG P+ D H
Sbjct: 2034 REHH-------------------VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPH 2074
Query: 958 KMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNS--FSLELVVAAKEAHKPPVFIEK 1015
+ G SL+++ + + DAG YTC+A N AG+++ ++ ++V PP +
Sbjct: 2075 LRFYLDGG--SLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLV-------PPTIKQG 2125
Query: 1016 LQNTGVADGYP---VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQ 1072
+G P V + C V G PP + W K+ L S R +H H L I
Sbjct: 2126 ADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLS-QRTLLHGSGH---TLRIS 2181
Query: 1073 GATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
DAG +T A + AG+ L V +
Sbjct: 2182 KVQLADAGIFTCVAASPAGVADRNFTLQVQV 2212
Score = 117 bits (294), Expect = 5e-26
Identities = 199/909 (21%), Positives = 325/909 (35%), Gaps = 161/909 (17%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V E V L C G PTP + WF +G L + + ++ GG L + A D G
Sbjct: 323 VMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKV-VYTRGG--RQLQLGRAQSSDAGV 379
Query: 342 YTCLATNPSGS--DTTSAEVF----IEGASSTDSDSESLA-----FKSRAGAMPQAQKKT 390
YTC A+N G+ T +V+ IEGA +++A + A P
Sbjct: 380 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSW 439
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---RPDGTTTAYF------PP 441
L + S+ T + L P + S Y C P G + PP
Sbjct: 440 HHEGLPVAESNESRLETDGSVLRLESPGEA--SSGLYSCVASSPAGEAVLQYSVEVQVPP 497
Query: 442 --VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
+ + L GQ + L C+ G+P +QW + G ++ ++ +
Sbjct: 498 QLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT----- 552
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESN--ND 557
TL I + +G+F C A N+ G+A + ++ V +G+ + +
Sbjct: 553 -----TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXE 607
Query: 558 HFQHFP--------------PPPPILE-----------TSSLELASKKPS--EIQQVNNP 590
H FP P PP++E + + +A P +I++V+
Sbjct: 608 HHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLR 667
Query: 591 ELGLSRAALQMQFNAAERET--NGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPP 648
+ G+ A ++RE + P G +N N S+ + + PPP
Sbjct: 668 DEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLA---SGVPPP 724
Query: 649 LLAKPKLGFPKKA------SRTARIASDEEIQ----GTKDAVIQDLERKLRFKEDLLNNG 698
++ K P + S R+ E+ Q G+ V ++ + L N
Sbjct: 725 DVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNV 784
Query: 699 QPRLTYEE------------RMARRLLGADSATVFNIQE--PEEETANQEYKVSSCEQRL 744
PR+T R+ GA S T+ +++ P +V R+
Sbjct: 785 PPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFP-GGRV 843
Query: 745 ISEIEYRLERS------PVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTC 798
++ R S V G++ Q DV ++ M P + + + V C
Sbjct: 844 LTLASARASDSGRYSCVAVSAVGEDRQ--DVVLQVHMPPSILGEELNVSVVANESVALEC 901
Query: 799 RVAGNPKPKIYWFKDGKQISPKSD-HYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 857
+ P P + W+KDG+ + P+ H + + L L + + D G+YT A N
Sbjct: 902 QSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-----LQVDRADVWDAGHYTCEALNQA 956
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP 917
GR L V +P P H
Sbjct: 957 GRSEKHYNLNVWV------APVFPLRESHT------------------------------ 980
Query: 918 GDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSR 977
LTV+EG + C+ G+P P +SW+ DG+P+ + A V G L +
Sbjct: 981 --LTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVG-RLLYLGQAQLA 1037
Query: 978 DAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI---EKLQNTGVADGYPVRLECRVL 1034
G YTC +N G +S L+L E H PP E V LEC
Sbjct: 1038 QEGTYTCECSNVVGNSSQDLQL-----EVHVPPQIAGPREPPTQVSVVQDGVATLECNAT 1092
Query: 1035 GVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 1094
G PPP + W+++ + + + + N G L ++ A G Y+ A+N AG
Sbjct: 1093 GKPPPTVTWERDGQPV---GAELGLQLQNQGQ-SLHVERAQAAHTGRYSCVAENLAGRAE 1148
Query: 1095 CTARLDVYI 1103
L V +
Sbjct: 1149 RKFELSVLV 1157
Score = 111 bits (277), Expect = 4e-24
Identities = 191/924 (20%), Positives = 318/924 (34%), Gaps = 195/924 (21%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
+V +G +L C VTG+P P++ WF +G+ L I +G L L +A G
Sbjct: 1265 KVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVL---QANLSSAG 1321
Query: 341 RYTCLATNPSGSDTTS-------AEVFIEGASSTDSDS-------------ESLAFKS-- 378
Y+C+A N G T A + GA + + E+LAF S
Sbjct: 1322 HYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPN 1381
Query: 379 ----RAGAMPQAQKK------TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYL 428
+ GA +A + T + + T V L V+ H L
Sbjct: 1382 ITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYH--VEVL 1439
Query: 429 CRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
P + V KE++ + LEC PP ++W++ G + S +
Sbjct: 1440 IPPSISKDDPLGEVGVKEVKTKV---NSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQ 1496
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT--------- 539
+L + +P ++ D+G + C A N G +++
Sbjct: 1497 VLGEGRLLQIQPTQV----------SDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVG 1546
Query: 540 --SANTENCSYESMGESNNDHFQHFPPPPP---ILETSSL---ELASKKPSEIQQVNNPE 591
SA E S E ++ P +T+++ +L + + + E
Sbjct: 1547 DFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGD-E 1605
Query: 592 LGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKE------ 645
+ + + +Q E G + + N + + + TP V+L T+E
Sbjct: 1606 VSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVT 1665
Query: 646 ----------------PPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLR 689
P P ++ + G P S ++ D ++ A + D +
Sbjct: 1666 VNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMC 1725
Query: 690 FKEDLLNNGQPRLTYEERMARRLLGADSATVFNI--------------QEPEEETANQEY 735
E+ + + T ++ R+ G D V I PE
Sbjct: 1726 VAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ 1785
Query: 736 KVSSCEQRLISEIEYRLE--RSPVDESG------------DE--VQYGD-VPVENGMAPF 778
+S E+ + + L+ R+ + +SG D+ VQ VP AP
Sbjct: 1786 ALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPR 1845
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD--LDGTCSL 836
++ G +C P+P + W+KDG+ + QR L G L
Sbjct: 1846 GPQDAVLVRV--GDKAVLSCETDALPEPTVTWYKDGQPL------VLAQRTQALRGGQRL 1897
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
+ + D G Y+ +N G T L VQ
Sbjct: 1898 EIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQV-------------------------- 1931
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQE--GKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
P + P TV + G + C VSG+P P ++W D PV
Sbjct: 1932 --------------PPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESS 1977
Query: 955 SAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIE 1014
+ H ++ R + ++P AG YTC+A N Q + VVA A
Sbjct: 1978 AVHGVVSRGGRLQLSRLQPA---QAGTYTCVAENT--QAEARKDFVVAVLVA-------P 2025
Query: 1015 KLQNTGVA------DGYPVRLECRVLGVPPPQIFWKKENESLTHST-DRVSMHQDNHGYI 1067
+++++GVA +G VRL+C G PPP + W K+ L + + D
Sbjct: 2026 RIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGS-- 2083
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAG 1091
L+++G DAG YT A N AG
Sbjct: 2084 -LVLKGLRASDAGAYTCVAHNPAG 2106
Score = 98.6 bits (244), Expect = 3e-20
Identities = 86/324 (26%), Positives = 133/324 (41%), Gaps = 60/324 (18%)
Query: 775 MAPFFEMKLKH-YKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKS---DHYTIQRDL 830
+AP F ++ H + EG P + +C G P PKI W KDG+ + + H + L
Sbjct: 969 VAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL 1028
Query: 831 DGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRP 890
L+ + L +G YT +N G S +L V P + P
Sbjct: 1029 -----LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVP-------------PQIAGP 1070
Query: 891 RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
R + P ++V + + ++C +G P P ++W+ DG+P
Sbjct: 1071 R-----------------------EPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQP 1107
Query: 951 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP 1010
V A L +N SL +E + G Y+C+A N AG+ EL V PP
Sbjct: 1108 V---GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLV-----PP 1159
Query: 1011 VFI---EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 1067
I + L N A P+ L C +G+PPP I W + E ++ D + G
Sbjct: 1160 ELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLL----AGGW 1215
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAG 1091
L + ++D+G Y+ A NEAG
Sbjct: 1216 MLKMTQTQEQDSGLYSCLASNEAG 1239
Score = 95.5 bits (236), Expect = 2e-19
Identities = 85/299 (28%), Positives = 121/299 (40%), Gaps = 48/299 (16%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
P+T C G P P I WF+ + +SP D Y L G L T + D G Y+ +
Sbjct: 1178 PLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYL----LAGGWMLKMTQTQEQDSGLYSCL 1233
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A+N + G + R+ S V P S ENE ++E
Sbjct: 1234 ASN-----------------EAGEARRNFS--VEVLVPPSI------ENEDLEEV----- 1263
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
+ V +G+ + C V+G P P L+W DG+P+ AH + +GV +++
Sbjct: 1264 -------IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHH--ISPDGVLLQVLQ 1314
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
S AG Y+CIA N G+ + +L V + V P+ L C
Sbjct: 1315 ANLS-SAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICE 1373
Query: 1033 VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
L P P I W K+ S + + + HG L I A KEDAG YT NE G
Sbjct: 1374 ALAFPSPNITWMKDGAPFEASRN-IQLLPGTHG---LQILNAQKEDAGQYTCVVTNELG 1428
Score = 92.4 bits (228), Expect = 2e-18
Identities = 97/380 (25%), Positives = 147/380 (38%), Gaps = 90/380 (23%)
Query: 784 KHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTL 843
+ + + EG V C G P P + W KDG + + ++ LDG SL
Sbjct: 2034 REHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPH-LRFYLDGG-SLVLKGLRA 2091
Query: 844 DDDGNYTIMAANPQGR-------------------------ISCTGRLMVQAVNQRGRSP 878
D G YT +A NP G +S G L+ RG P
Sbjct: 2092 SDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPP 2151
Query: 879 -------------------RSPSGHPHVRRPRSRSRDSG-------------DENEPIQE 906
SGH +R + + D+G D N +Q
Sbjct: 2152 IHVSWLKDGLPLPLSQRTLLHGSGHT-LRISKVQLADAGIFTCVAASPAGVADRNFTLQV 2210
Query: 907 RFFRPHFLQA---PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 963
+ P L+ D+ V G L + C+ G+P P +SW DG+P+ S E
Sbjct: 2211 QV--PPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL------E 2262
Query: 964 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT--GV 1021
G SL +E V + D+G Y+C+A + AG+ +L V +PP + Q T +
Sbjct: 2263 QG-PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVM-----EPPHIEDSGQPTELSL 2316
Query: 1022 ADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGW 1081
G P+ L C G P P I W K+ ++LT + ++ L ++ DAG
Sbjct: 2317 TPGAPMELLCDAQGTPQPNITWHKDGQALTR------LENNSRATRVLRVR-----DAGL 2365
Query: 1082 YTVSAKNEAGIVSCTARLDV 1101
YT A++ AG + + R+ V
Sbjct: 2366 YTCLAESPAGAIEKSFRVRV 2385
Score = 92.0 bits (227), Expect = 3e-18
Identities = 189/879 (21%), Positives = 307/879 (34%), Gaps = 141/879 (16%)
Query: 254 NRKSHPQPHSALHFPAAPRF-IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELH 312
N+ + H L+ AP F +++ + V EG L C G P P++ W +G+ L
Sbjct: 954 NQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLP 1013
Query: 313 NTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGAS------- 365
H L + +A G YTC +N G+ + ++ +
Sbjct: 1014 GEGAGLQHVSAVG-RLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 1072
Query: 366 -----STDSDSESLAFKSRAGAMPQA---QKKTTSVSLTIGSSSPKTGVTTAVIQPLSVP 417
S D + + G P ++ V +G G Q L V
Sbjct: 1073 PPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG------QSLHVE 1126
Query: 418 VQQVHSPTSYLCRPDGTT---------TAYFPPVFTKELQ---NTAVAEGQVVVLECRVR 465
Q Y C + + PP +L N A + L C
Sbjct: 1127 RAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAM 1186
Query: 466 GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARN 525
G PP ++WFR + D +L L + +T +D+G+++C A N
Sbjct: 1187 GIPPPAIRWFRGEEPVSPGEDTYLLAGG----------WMLKMTQTQEQDSGLYSCLASN 1236
Query: 526 DYGSATSTAQL-VVTSANTENCSYESMGESNNDHFQHF-------PPPPPILETSSLELA 577
+ G A + V+ + EN E + + + H P P LA
Sbjct: 1237 EAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLA 1296
Query: 578 SKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPA 637
I +P+ G+ LQ ++A G + N + G+ + L +
Sbjct: 1297 RGDAHHI----SPD-GVLLQVLQANLSSA-----GHYSCIAANAV--GEKTKHFQL---S 1341
Query: 638 VLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN 697
VLL+PT LG A ++DEE+ T + I + L F +
Sbjct: 1342 VLLAPT----------ILG-------GAEDSADEEVTVTVNNPISLICEALAFPSPNITW 1384
Query: 698 GQPRLTYE-ERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSP 756
+ +E R + L G + N Q +E+ V++ + + P
Sbjct: 1385 MKDGAPFEASRNIQLLPGTHGLQILNAQ--KEDAGQYTCVVTNELGEAVKNYHVEVLIPP 1442
Query: 757 VDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 816
D + G+V V K K +T C P P I W+KDG+
Sbjct: 1443 SISKDDPL--GEVGV------------KEVKTKVNSTLTLECESWAVPPPTIRWYKDGQP 1488
Query: 817 ISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR 876
++P S +Q +G L + + D G Y +A N G +++Q V +
Sbjct: 1489 VTPSS---RLQVLGEGRL-LQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ-VPPMFQ 1543
Query: 877 SPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSG 936
S + +R E I E P +L C +
Sbjct: 1544 KVGDFSAAFEILSREEEARGGVTEYREIVEN--NPAYLY----------------CDTNA 1585
Query: 937 LPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFS 996
+P PDL+W + +P+ +L G L I V + +AG Y+C A+N G++
Sbjct: 1586 IPPPDLTWYREDQPLSAGDEVSVL---QGGRVLQIPLVRAENAGRYSCKASNEVGEDWLH 1642
Query: 997 LELVVAAKEAHKPPVFI----EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTH 1052
EL+V PPV + E ++ V V L+C LG P P I W + +
Sbjct: 1643 YELLVLT-----PPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSP 1697
Query: 1053 STDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
S R+ + +D L + A DA Y A+N+AG
Sbjct: 1698 S-PRLQVLEDGQ---VLQVSTAEVADAASYMCVAENQAG 1732
Score = 91.7 bits (226), Expect = 4e-18
Identities = 85/317 (26%), Positives = 123/317 (38%), Gaps = 52/317 (16%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
+ E VT C +G P P + WFK G Q P S + +DG L + L D G
Sbjct: 706 VLENASVTLECLASGVPPPDVSWFK-GHQ--PVSSWMGVTVSVDGRV-LRIEQAQLSDAG 761
Query: 848 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 907
+Y +A+N G L V P + P S
Sbjct: 762 SYRCVASNVAGSTELRYGLRVNVP-------------PRITLPPS--------------- 793
Query: 908 FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
PG + V R+ C +G P+P L W DG PV P + V G
Sbjct: 794 --------LPGPVLVNTP--VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGG-R 842
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
L + + D+G Y+C+A + G++ + L V H PP + + N V V
Sbjct: 843 VLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV-----HMPPSILGEELNVSVVANESV 897
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 1087
LEC+ +PPP + W K+ L R +H + L + A DAG YT A
Sbjct: 898 ALECQSHAMPPPVLSWWKDGRPL---EPRPGVHLSADKAL-LQVDRADVWDAGHYTCEAL 953
Query: 1088 NEAGIVSCTARLDVYIS 1104
N+AG L+V+++
Sbjct: 954 NQAGRSEKHYNLNVWVA 970
Score = 89.4 bits (220), Expect = 2e-17
Identities = 79/303 (26%), Positives = 118/303 (38%), Gaps = 64/303 (21%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P+ C G P+P I W KDG+ ++ ++ S T + D G YT
Sbjct: 2319 GAPMELLCDAQGTPQPNITWHKDGQALTRLENN-----------SRATRVLRVRDAGLYT 2367
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
+A +P G I + R+ VQA P++ PR
Sbjct: 2368 CLAESPAGAIEKSFRVRVQA-------------PPNIVGPRG------------------ 2396
Query: 911 PHFL--QAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS 968
P F+ APG L ++C V P P ++W DG ++ D AH
Sbjct: 2397 PRFVVGLAPGQLV--------LECSVEAEPAPKITWHRDGIVLQED-AHTQFPERG--RF 2445
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
L ++ +++ D+G Y+C A N AG S + + E H P V+
Sbjct: 2446 LQLQALSTADSGDYSCTARNAAGSTSVAFRV-----EIHTVPTIRSGPPAVNVSVNQTAL 2500
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L C+ GVP P + W+K+ L + R + + L IQ +DAG Y A N
Sbjct: 2501 LPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG----SLRIQPVLAQDAGHYLCLASN 2556
Query: 1089 EAG 1091
AG
Sbjct: 2557 SAG 2559
Score = 89.0 bits (219), Expect = 2e-17
Identities = 93/321 (28%), Positives = 118/321 (36%), Gaps = 38/321 (11%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLD-GTCSLHTTASTLDDDGNY 849
G +T C G P P+I W KD + + DL G H L D+G
Sbjct: 111 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHR----LLDEGQS 166
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 909
GR GR G + P +G E P F
Sbjct: 167 LHFPRIQPGR--------------SGRRGAQAGGSAQTKAPWXAGL-AGFEQFPTPHAFS 211
Query: 910 RPHFLQAPGDLTVQE-----GKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 964
P G QE G + C SG+PTP + W D +PV P H + V+E+
Sbjct: 212 PPAPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPH-LQVQED 270
Query: 965 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF--IEKLQNTGVA 1022
G L I D G Y C+A + AGQ + +L V H PP + V
Sbjct: 271 G-QVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRV-----HAPPTIWGSNETGEVAVM 324
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
+ + V+L C GVP P I W K+ L ST V G L + A DAG Y
Sbjct: 325 EDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVY----TRGGRQLQLGRAQSSDAGVY 380
Query: 1083 TVSAKNEAGIVSCTARLDVYI 1103
T A N G RLDVY+
Sbjct: 381 TCKASNAVGAAEKATRLDVYV 401
Score = 89.0 bits (219), Expect = 2e-17
Identities = 86/323 (26%), Positives = 123/323 (38%), Gaps = 71/323 (21%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ-------RD 829
P E L EG C+ G+P+P I W KDG+ +S +TIQ ++
Sbjct: 2847 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 2906
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889
L+G D G YT A N GR L + +
Sbjct: 2907 LEG-----------QDAGTYTCTAENAVGRARRRVHLTILVL------------------ 2937
Query: 890 PRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGK 949
P F PGD +++ G + C G PTP + W ++ +
Sbjct: 2938 ---------------------PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDR 2976
Query: 950 PVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP 1009
PV + + ++G +L V+ D+G Y C A NR G+ V KEA P
Sbjct: 2977 PVT-----EGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEA--P 3027
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
+ E G ++L+C V G P P I W K+ L S R HQ +G L
Sbjct: 3028 VLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLR---HQLQNG--SL 3082
Query: 1070 LIQGATKEDAGWYTVSAKNEAGI 1092
I ++DAG Y A+NE G+
Sbjct: 3083 TIHRTERDDAGRYQCLAENEMGV 3105
Score = 82.8 bits (203), Expect = 2e-15
Identities = 77/299 (25%), Positives = 113/299 (37%), Gaps = 56/299 (18%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
PV TC G P P + W K G Q+ + Y + + +L + G YT
Sbjct: 2682 PVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP----SGALEIGQALPIHAGRYTCS 2737
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A N G L VQA SP P P
Sbjct: 2738 ARNSAGVAHKHVFLTVQA---------SPVVKP------------------------LPS 2764
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
++A + V + C+ SG+P P ++WQ +G V + ++L L I
Sbjct: 2765 VVRAVAEEEVL------LPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ----LRIA 2814
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
+ DAG Y CIA N AG LVV PPV L + +G L C+
Sbjct: 2815 HASPEDAGNYLCIAKNSAGSAMGKTRLVVQV-----PPVIENGLPDLSTTEGSHAFLPCK 2869
Query: 1033 VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
G P P I W K+ + ++ + + ++ LL++ +DAG YT +A+N G
Sbjct: 2870 ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE----LLVKNLEGQDAGTYTCTAENAVG 2924
Score = 82.4 bits (202), Expect = 2e-15
Identities = 72/298 (24%), Positives = 113/298 (37%), Gaps = 58/298 (19%)
Query: 794 VTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMA 853
V C +G P+P I W K+G ++ + L ++ +D GNY +A
Sbjct: 2774 VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGG-----QLRIAHASPEDAGNYLCIA 2828
Query: 854 ANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHF 913
N G RL+VQ P +G P
Sbjct: 2829 KNSAGSAMGKTRLVVQV------PPVIENGLP---------------------------- 2854
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEP 973
DL+ EG + CK G P P+++W DG+PV + K ++ +G L+++
Sbjct: 2855 -----DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV-SGAEGKFTIQPSG--ELLVKN 2906
Query: 974 VTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRV 1033
+ +DAG YTC A N G+ + L + PVF + + G + L C
Sbjct: 2907 LEGQDAGTYTCTAENAVGRARRRVHLTILVL-----PVFTTLPGDRSLRLGDRLWLRCAA 2961
Query: 1034 LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
G P P+I W + +T + G L ++ED+G Y A+N G
Sbjct: 2962 RGSPTPRIGWTVNDRPVTEGV------SEQDGGSTLQRAAVSREDSGTYVCWAENRVG 3013
Score = 77.8 bits (190), Expect = 5e-14
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 78/323 (24%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
+ G V C G P P + W KDG+ + + + L+ SL A D G
Sbjct: 2227 VVRGSLVELPCEARGVPLPLVSWMKDGEPL--------LSQSLEQGPSLQLEAVGAGDSG 2278
Query: 848 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 907
Y+ +A + G +L V PH+ DSG
Sbjct: 2279 TYSCVAVSEAGEARRHFQLTVME-------------PPHI-------EDSGQ-------- 2310
Query: 908 FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
P +L++ G + C G P P+++W DG+ + EN +
Sbjct: 2311 ---------PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQ--------ALTRLEN--N 2351
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---AHKPPVFIEKLQNTGVADG 1024
S + RDAG+YTC+A + AG S + V A + P F+ G+A G
Sbjct: 2352 SRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFV-----VGLAPG 2406
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI-----CLLIQGATKEDA 1079
V LEC V P P+I W + D + + +D H L +Q + D+
Sbjct: 2407 QLV-LECSVEAEPAPKITWHR---------DGIVLQEDAHTQFPERGRFLQLQALSTADS 2456
Query: 1080 GWYTVSAKNEAGIVSCTARLDVY 1102
G Y+ +A+N AG S R++++
Sbjct: 2457 GDYSCTARNAAGSTSVAFRVEIH 2479
Score = 71.6 bits (174), Expect = 4e-12
Identities = 80/321 (24%), Positives = 120/321 (37%), Gaps = 58/321 (18%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
+ E V C G P P I WFKDG + P S R G L + D G
Sbjct: 323 VMEDHLVQLLCEARGVPTPNITWFKDGALL-PTSTKVVYTR---GGRQLQLGRAQSSDAG 378
Query: 848 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 907
YT A+N G RL V P + G
Sbjct: 379 VYTCKASNAVGAAEKATRLDVYV-------------------PPTIEGAGG--------- 410
Query: 908 FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
RP+ ++A G+ ++C G P+P LSW +G PV + ++ E
Sbjct: 411 --RPYVVKAVA------GRPVALECVARGHPSPTLSWHHEGLPVAESNESRL---ETDGS 459
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI--EKLQNTGVADGY 1025
L +E +G+Y+C+A++ AG+ ++ + E PP + E L G
Sbjct: 460 VLRLESPGEASSGLYSCVASSPAGE-----AVLQYSVEVQVPPQLLVAEGLGQVTTIVGQ 514
Query: 1026 PVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVS 1085
P+ L C+ G P P I W + + + + + G L I + +G +
Sbjct: 515 PLELPCQASGSPVPTIQWLQNGRP---AEELAGVQVASQG-TTLHIDHVELDHSGLFACQ 570
Query: 1086 AKNEAGIVSCTARLDVYISRH 1106
A NEAG TA +V +S H
Sbjct: 571 ATNEAG----TAGAEVEVSVH 587
Score = 70.1 bits (170), Expect = 1e-11
Identities = 56/211 (26%), Positives = 87/211 (41%), Gaps = 48/211 (22%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G + C V G+P P I+W KDG + + +Q +G+ ++H T DD G Y
Sbjct: 3042 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ---NGSLTIHRTER--DDAGRYQ 3096
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
+A N G L++Q+
Sbjct: 3097 CLAENEMGVAKKVVILVLQSA--------------------------------------- 3117
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F P D+TV+ G + C+ +G PTP + W G+P+R ++ ++ +G SL
Sbjct: 3118 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLR--ASRRLRTLPDG--SLW 3173
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+E V + DAG Y C+A N G + LVV
Sbjct: 3174 LENVETGDAGTYDCVAHNLLGSATARAFLVV 3204
Score = 68.9 bits (167), Expect = 2e-11
Identities = 73/300 (24%), Positives = 114/300 (38%), Gaps = 63/300 (21%)
Query: 798 CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 857
C+ G P P + W KD + P+S + I + SL D G+Y +A+N
Sbjct: 2503 CQADGVPAPLVSWRKDRVPLDPRSPRFEILPE----GSLRIQPVLAQDAGHYLCLASNSA 2558
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP 917
G +++GR R V P P +P
Sbjct: 2559 GS------------DRQGRDLR-------VLEP--------------------PAIAPSP 2579
Query: 918 GDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR---PDSAHKMLVRENGVHSLIIEPV 974
+LT+ + C+ SG P P + W DG+ + A+++L ++L++
Sbjct: 2580 SNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPS----NALLLTAP 2635
Query: 975 TSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVL 1034
+D+ + C+ +N G+ ++ V H PP + + V PV L C
Sbjct: 2636 GPQDSAQFECVVSNEVGEAHRLYQVTV-----HVPPTIADDQTDFTVTMMAPVVLTCHST 2690
Query: 1035 GVPPPQIFWKKENESL--THSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGI 1092
G+P P + W K L S RVS L I A AG YT SA+N AG+
Sbjct: 2691 GIPAPTVSWSKAGAQLGARGSGYRVSPSG------ALEIGQALPIHAGRYTCSARNSAGV 2744
Score = 68.6 bits (166), Expect = 3e-11
Identities = 77/290 (26%), Positives = 109/290 (37%), Gaps = 53/290 (18%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT--PDIQIHCEGGDLHTLIIAEAF 335
R V EG V L+C G P P V W +G L P ++ + +GG +L++
Sbjct: 2034 REHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG---SLVLKGLR 2090
Query: 336 EDDTGRYTCLATNPSGSDTT--SAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSV 393
D G YTC+A NP+G D + V + +D S SR G + T V
Sbjct: 2091 ASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADG-SGTLVSRPGEL------VTMV 2143
Query: 394 SLTIGS-----SSPKTGVTTAVIQ---------PLSVPVQQVHSPTSYLC---RPDGTTT 436
GS S K G+ + Q L + Q+ + C P G
Sbjct: 2144 CPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD 2203
Query: 437 AYF------PPVFTK-ELQN-TAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
F PPV E QN V G +V L C RG P V W + G
Sbjct: 2204 RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDG---------- 2253
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+P + E+ +L + D+G ++C A ++ G A QL V
Sbjct: 2254 ----EPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTV 2299
Score = 65.1 bits (157), Expect = 4e-10
Identities = 85/313 (27%), Positives = 117/313 (37%), Gaps = 58/313 (18%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
P C +G+PKP + W+KDG+++ + L A L +
Sbjct: 2589 PALLPCEASGSPKPLVVWWKDGQKLDFR---------------LQQGAYRLLPSNALLLT 2633
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A PQ + + N+ G + R HV P + + D D
Sbjct: 2634 APGPQD----SAQFECVVSNEVGEAHRLYQVTVHV--PPTIADDQTDFTVT--------- 2678
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
+ AP LT C +G+P P +SW G + A R + +L I
Sbjct: 2679 -MMAPVVLT----------CHSTGIPAPTVSWSKAGAQL---GARGSGYRVSPSGALEIG 2724
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
AG YTC A N AG + L V A KP + + VA+ V L C
Sbjct: 2725 QALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVR----AVAEE-EVLLPCE 2779
Query: 1033 VLGVPPPQIFWKKE--NESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1090
G+P P I W+KE N + ST + Q L I A+ EDAG Y AKN A
Sbjct: 2780 ASGIPRPTITWQKEGLNVATGVSTQVLPGGQ-------LRIAHASPEDAGNYLCIAKNSA 2832
Query: 1091 GIVSCTARLDVYI 1103
G RL V +
Sbjct: 2833 GSAMGKTRLVVQV 2845
Score = 64.3 bits (155), Expect = 6e-10
Identities = 73/324 (22%), Positives = 120/324 (37%), Gaps = 40/324 (12%)
Query: 234 VKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECR 293
V+ G C ++ A+ + + Q + P PRF+ L A G V LEC
Sbjct: 2360 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGL-----APGQLV-LECS 2413
Query: 294 VTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSD 353
V P P++ W +G L Q G L ++ A D+G Y+C A N +GS
Sbjct: 2414 VEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTA---DSGDYSCTARNAAGST 2470
Query: 354 TTSAEVFIEGASSTDSD--------SESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTG 405
+ + V I + S +++ +A +P + + SP+
Sbjct: 2471 SVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPR-- 2528
Query: 406 VTTAVIQPLSVPVQQVHSPTS--YLC---------RPDGTTTAYFPPVFTKELQNTAVAE 454
++ S+ +Q V + + YLC R PP N +
Sbjct: 2529 --FEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA 2586
Query: 455 GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPE 514
+L C G+P V W++ G ++ DFR+ Q R L++ P+
Sbjct: 2587 HTPALLPCEASGSPKPLVVWWKDGQKL----DFRLQQGAYRLLPSN----ALLLTAPGPQ 2638
Query: 515 DAGIFTCSARNDYGSATSTAQLVV 538
D+ F C N+ G A Q+ V
Sbjct: 2639 DSAQFECVVSNEVGEAHRLYQVTV 2662
Score = 63.5 bits (153), Expect = 1e-09
Identities = 65/270 (24%), Positives = 96/270 (35%), Gaps = 37/270 (13%)
Query: 288 VYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLAT 347
V L C TG P P V W G +L G L I +A GRYTC A
Sbjct: 2683 VVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALE---IGQALPIHAGRYTCSAR 2739
Query: 348 NPSGSD------TTSAEVFIEGASSTDSD--SESLAFKSRAGAMPQAQKKTTSVSLTIGS 399
N +G T A ++ S E + A +P+ L +
Sbjct: 2740 NSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVA- 2798
Query: 400 SSPKTGVTTAVIQ--PLSVPVQQVHSPTSYLCRPDGTT---------TAYFPPVFTKELQ 448
TGV+T V+ L + +YLC + PPV L
Sbjct: 2799 ----TGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLP 2854
Query: 449 NTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVI 508
+ + EG L C+ RG+P + W + G + + + + T +P L++
Sbjct: 2855 DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGA--------EGKFTIQPSG--ELLV 2904
Query: 509 AETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+DAG +TC+A N G A L +
Sbjct: 2905 KNLEGQDAGTYTCTAENAVGRARRRVHLTI 2934
Score = 63.2 bits (152), Expect = 1e-09
Identities = 59/198 (29%), Positives = 82/198 (41%), Gaps = 17/198 (8%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P+ P + V E ++C SG+P PD+SW +PV S + V +G L
Sbjct: 695 PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMGVTVSVDG-RVLR 751
Query: 971 IEPVTSRDAGIYTCIATNRAGQNS--FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
IE DAG Y C+A+N AG + L + V + P + L NT PVR
Sbjct: 752 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNT------PVR 805
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L C G P P + W K+ + S Q G L + A D+G Y+ A +
Sbjct: 806 LTCNATGAPSPTLMWLKDGNPV--SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 863
Query: 1089 EAGIVSCTARLDVYISRH 1106
G R DV + H
Sbjct: 864 AVG----EDRQDVVLQVH 877
Score = 60.1 bits (144), Expect = 1e-08
Identities = 62/290 (21%), Positives = 103/290 (35%), Gaps = 55/290 (18%)
Query: 280 QEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDT 339
+E+ E + YL C P P + W+ E + L ++ + +GG + + + A ++
Sbjct: 1569 REIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSV-LQGGRVLQIPLVRA--ENA 1625
Query: 340 GRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGS 399
GRY+C A+N G D E+ + D+E L ++ T + S T+
Sbjct: 1626 GRYSCKASNEVGEDWLHYELLVLTPPVILGDTEEL-----------VEEVTVNASSTVSL 1674
Query: 400 SSPKTGVTTAVI---------------------QPLSVPVQQVHSPTSYLCRPD---GTT 435
P G I Q L V +V SY+C + G+
Sbjct: 1675 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 1734
Query: 436 TAYF-------PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
F P + +L+ V L C V P +V W++ + +
Sbjct: 1735 EKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVF 1794
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+L TL + D+G++TC A N G QL V
Sbjct: 1795 LLPGTH----------TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSV 1834
Score = 60.1 bits (144), Expect = 1e-08
Identities = 112/468 (23%), Positives = 167/468 (35%), Gaps = 75/468 (16%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
VAE V L C +G P P + W EG + Q+ GG L IA A +D G
Sbjct: 2769 VAE-EEVLLPCEASGIPRPTITWQKEGLNVATGVSTQV-LPGGQLR---IAHASPEDAGN 2823
Query: 342 YTCLATNPSGSDTTSAEVFIE----------GASSTDSDSESLAFKSRAGAMPQA--QKK 389
Y C+A N +GS + ++ S+T+ L K+R P K
Sbjct: 2824 YLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKD 2883
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQP---LSVPVQQVHSPTSYLCRPDGTT---------TA 437
VS G + IQP L V + +Y C + T
Sbjct: 2884 GQPVSGAEGKFT---------IQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 2934
Query: 438 YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
PVFT + ++ G + L C RG+P ++ W + D P
Sbjct: 2935 LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGW-----TVNDRP-------VTEGV 2982
Query: 498 AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA---NTENCSY--ESMG 552
+E + TL A ED+G + C A N G + + + V A E SY E +G
Sbjct: 2983 SEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVG 3042
Query: 553 ES-NNDHFQHFPPPPPI--------LETSSLELASKKPS-EIQQVNNPELGLSRAALQMQ 602
S D P P I L S L + S I + + G + + +
Sbjct: 3043 GSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENE 3102
Query: 603 FNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKAS 662
A++ V S V + + + +S A+ T EP P + + G P +AS
Sbjct: 3103 MGVAKKVVILVLQSAPV-FQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRAS 3161
Query: 663 RTARIASDEEI---------QGTKDAVIQDLERKLRFKEDLLNNGQPR 701
R R D + GT D V +L + L+ G+P+
Sbjct: 3162 RRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3209
Score = 58.9 bits (141), Expect = 3e-08
Identities = 57/268 (21%), Positives = 99/268 (36%), Gaps = 31/268 (11%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDD 338
++ V E + V LEC +G P P V WF + + + + + +G L I +A D
Sbjct: 703 NKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG---RVLRIEQAQLSD 759
Query: 339 TGRYTCLATNPSGSDTTSAEVFIE---GASSTDSDSESLAFKSRAGAMPQAQKKTTSVSL 395
G Y C+A+N +GS + + + S + + A + +
Sbjct: 760 AGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLM 819
Query: 396 TIGSSSPKTGVTTAVIQ------PLSVPVQQVHSPTSYLC---------RPDGTTTAYFP 440
+ +P + T +Q L++ + Y C R D + P
Sbjct: 820 WLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMP 879
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P E N +V + V LEC+ PP + W++ G ++ P + K +
Sbjct: 880 PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDR 939
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYG 528
++ DAG +TC A N G
Sbjct: 940 ADVW----------DAGHYTCEALNQAG 957
Score = 57.8 bits (138), Expect = 6e-08
Identities = 67/296 (22%), Positives = 114/296 (38%), Gaps = 39/296 (13%)
Query: 259 PQPHSALHFPAAPRFIQKLRSQEVA--EGSRVYLECRVTGNPTPRVRWFCEGKE-LHNTP 315
P PH A PA P + +QEV G+ V L+C +G PTP+V W + + L P
Sbjct: 205 PTPH-AFSPPAPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGP 263
Query: 316 DIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASS---TDSDSE 372
+Q+ +G L I + D GRY C+A +P+G ++ + + ++ E
Sbjct: 264 HLQVQEDG---QVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGE 320
Query: 373 SLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVI-----QPLSVPVQQVHSPTSY 427
+ + + + ++T +T V+ + L + Q Y
Sbjct: 321 VAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVY 380
Query: 428 LCRPDGTTTA---------YFPPVFT----KELQNTAVAEGQVVVLECRVRGAPPLQVQW 474
C+ A Y PP + AVA G+ V LEC RG P + W
Sbjct: 381 TCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVA-GRPVALECVARGHPSPTLSW 439
Query: 475 FRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSA 530
+G + +S + R+ + L + +G+++C A + G A
Sbjct: 440 HHEGLPVAESNESRL----------ETDGSVLRLESPGEASSGLYSCVASSPAGEA 485
Score = 57.4 bits (137), Expect = 7e-08
Identities = 69/304 (22%), Positives = 107/304 (35%), Gaps = 36/304 (11%)
Query: 249 LAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAE--GSRVYLECRVTGNPTPRVRWFC 306
+ V N+ + L PR I L ++V S V L C V +P P V W+
Sbjct: 1724 MCVAENQAGSAEKLFTLRVQVPPR-IAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYK 1782
Query: 307 EGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI----- 361
+ + L ++ + HTL + A D+G YTC A N +G D ++ +
Sbjct: 1783 DSQALSLGEEVFLL---PGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPA 1839
Query: 362 ---EGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVI--QPLSV 416
D+ + K+ A + T G T A+ Q L +
Sbjct: 1840 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEI 1899
Query: 417 PVQQVHSPTSYLCRPDG---------TTTAYFPPVF-TKELQNTAVAEGQVVVLECRVRG 466
QV Y C+ T T PP F + + + G +VL C V G
Sbjct: 1900 QEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSG 1959
Query: 467 APPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARND 526
P V W + ++ S ++ + R L ++ P AG +TC A N
Sbjct: 1960 VPAPTVTWLKDRMPVESSAVHGVVSRGGR----------LQLSRLQPAQAGTYTCVAENT 2009
Query: 527 YGSA 530
A
Sbjct: 2010 QAEA 2013
Score = 57.0 bits (136), Expect = 1e-07
Identities = 72/310 (23%), Positives = 110/310 (35%), Gaps = 34/310 (10%)
Query: 249 LAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEG 308
L + N + L P L EGS +L C+ G+P P + W +G
Sbjct: 2825 LCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDG 2884
Query: 309 KELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASS 366
+ + G+ L++ D G YTC A N G + + +
Sbjct: 2885 QPVSGAEGKFTIQPSGE---LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFT 2941
Query: 367 TDSDSESLAFKSRAGAMPQAQ-KKTTSVSLTIGSSSPKTGVTT----AVIQPLSVPVQQV 421
T SL R A+ T + T+ GV+ + +Q +V +
Sbjct: 2942 TLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSRE-- 2999
Query: 422 HSPTSYLCRPDGTT--TAYFPPVFTKE---LQNTAVA-----EGQVVVLECRVRGAPPLQ 471
+Y+C + T V KE LQ A + G + L+C VRG P
Sbjct: 3000 -DSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPD 3058
Query: 472 VQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSAT 531
+ W + G ++ S LQ +L I T +DAG + C A N+ G A
Sbjct: 3059 IHWIKDGLPLRGSHLRHQLQNG-----------SLTIHRTERDDAGRYQCLAENEMGVAK 3107
Query: 532 STAQLVVTSA 541
LV+ SA
Sbjct: 3108 KVVILVLQSA 3117
Score = 53.9 bits (128), Expect = 8e-07
Identities = 68/293 (23%), Positives = 104/293 (35%), Gaps = 62/293 (21%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELH-NTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
V+ L C+ G P P V W + L +P +I EG +L I D G
Sbjct: 2493 VSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG----SLRIQPVLAQDAG 2548
Query: 341 RYTCLATNPSGSDTTSAEVFI-------------------------EGASSTD------S 369
Y CLA+N +GSD ++ + E + S
Sbjct: 2549 HYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWK 2608
Query: 370 DSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC 429
D + L F+ + GA + S +L + + P+ + +S V + H
Sbjct: 2609 DGQKLDFRLQQGAY----RLLPSNALLLTAPGPQDSAQFECV--VSNEVGEAHRLYQ--- 2659
Query: 430 RPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEI-QDSPDFR 488
T + PP + + V VVL C G P V W + G+++ +R
Sbjct: 2660 -----VTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYR 2714
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA 541
+ P E I + P AG +TCSARN G A L V ++
Sbjct: 2715 V---SPSGALE--------IGQALPIHAGRYTCSARNSAGVAHKHVFLTVQAS 2756
Score = 52.8 bits (125), Expect = 2e-06
Identities = 39/118 (33%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Query: 932 CKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAG 991
C G P P ++W+ + V E G SL + V+ D+G Y C ATN G
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEG--SLFLASVSPADSGDYECQATNEVG 81
Query: 992 QNSFSLELVVAAKEAHKPPVFIE---KLQNTGVADGYPVRLECRVLGVPPPQIFWKKE 1046
S +LVV + PP E K +G+A G + LEC G P P+I W K+
Sbjct: 82 STSRRAKLVV-----YVPPSIREDGRKANVSGMA-GQSLTLECDANGFPVPEIVWLKD 133
Score = 48.9 bits (115), Expect = 3e-05
Identities = 63/282 (22%), Positives = 99/282 (35%), Gaps = 45/282 (15%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGK-----ELHNTPDIQIHCEGGDLHTLIIAEAFE 336
V GS V L C G P P V W +G+ L P +Q+ G
Sbjct: 2227 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAG----------- 2275
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQA---QKKTTSV 393
D+G Y+C+A + +G ++ + + + GA + + T
Sbjct: 2276 -DSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQP 2334
Query: 394 SLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---RPDGTTTAYF------PPVFT 444
++T +T + V +V Y C P G F PP
Sbjct: 2335 NITWHKDGQ--ALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIV 2392
Query: 445 KELQNTAV---AEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
V A GQ+V LEC V P ++ W R G +Q+ T PE
Sbjct: 2393 GPRGPRFVVGLAPGQLV-LECSVEAEPAPKITWHRDGIVLQEDAH----------TQFPE 2441
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT 543
L + D+G ++C+ARN GS + ++ + + T
Sbjct: 2442 RGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPT 2483
Score = 48.5 bits (114), Expect = 3e-05
Identities = 70/301 (23%), Positives = 106/301 (35%), Gaps = 48/301 (15%)
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
+H P P + + + V V LEC+ P P + W+ +G+ L P + +
Sbjct: 876 VHMP--PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHL---SA 930
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGS-------DTTSAEVFIEGASST----DSDSES 373
D L + A D G YTC A N +G + A VF S T + S
Sbjct: 931 DKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTS 990
Query: 374 LAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGV----TTAVIQPLSVPVQQVHSPTSYLC 429
L+ + R P+ + G P G +AV + L + Q+ +Y C
Sbjct: 991 LSCECRGVPFPKISWRKD------GQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTC 1044
Query: 430 R---------PDGTTTAYFPPVFTKELQ---NTAVAEGQVVVLECRVRGAPPLQVQWFRQ 477
D + PP + +V + V LEC G PP V W R
Sbjct: 1045 ECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERD 1104
Query: 478 GSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLV 537
G + + LQ + +S L + G ++C A N G A +L
Sbjct: 1105 GQPVGAELGLQ-LQNQGQS---------LHVERAQAAHTGRYSCVAENLAGRAERKFELS 1154
Query: 538 V 538
V
Sbjct: 1155 V 1155
Score = 48.5 bits (114), Expect = 3e-05
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
+AP F + + V G V L C+ TG PTP + W G+ L + ++ +G +
Sbjct: 3116 SAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG----S 3171
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
L + D G Y C+A N GS T A + + G
Sbjct: 3172 LWLENVETGDAGTYDCVAHNLLGSATARAFLVVRG 3206
Score = 46.6 bits (109), Expect = 1e-04
Identities = 41/140 (29%), Positives = 58/140 (41%), Gaps = 13/140 (9%)
Query: 254 NRKSHPQPHSALHFPAAPRFIQKLRSQEVAE-GSRVYLECRVTGNPTPRVRWFCEGKELH 312
NR Q S +H AP + S V G + L+C V G+P P + W +G L
Sbjct: 3010 NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR 3069
Query: 313 NTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSD-------TTSAEVF-IEGA 364
+ ++ + G +L I DD GRY CLA N G SA VF +E
Sbjct: 3070 GS-HLRHQLQNG---SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQ 3125
Query: 365 SSTDSDSESLAFKSRAGAMP 384
T + +A + +A P
Sbjct: 3126 DMTVRSGDDVALRCQATGEP 3145
Score = 42.7 bits (99), Expect = 0.002
Identities = 33/118 (27%), Positives = 47/118 (39%), Gaps = 13/118 (11%)
Query: 423 SPTSYLCRPDGTTTAYFPPVF--TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
SP R D + PP + E AV E +V L C RG P + WF+ G+
Sbjct: 293 SPAGQQAR-DFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGAL 351
Query: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ S + + R L + DAG++TC A N G+A +L V
Sbjct: 352 LPTSTKV-VYTRGGRQ---------LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDV 399
Score = 40.8 bits (94), Expect = 0.007
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 6/92 (6%)
Query: 292 CRVTGNPTPRVRWFC--EGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNP 349
C G P P+V W + LH P + + EG +L +A D+G Y C ATN
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEG----SLFLASVSPADSGDYECQATNE 79
Query: 350 SGSDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
GS + A++ + S D AG
Sbjct: 80 VGSTSRRAKLVVYVPPSIREDGRKANVSGMAG 111
Score = 36.6 bits (83), Expect = 0.14
Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 5/74 (6%)
Query: 1031 CRVLGVPPPQIFWKKENESLT-HSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
C G P PQ+ W+K S H V++ ++ L + + D+G Y A NE
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGS----LFLASVSPADSGDYECQATNE 79
Query: 1090 AGIVSCTARLDVYI 1103
G S A+L VY+
Sbjct: 80 VGSTSRRAKLVVYV 93
Score = 36.6 bits (83), Expect = 0.14
Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 13/79 (16%)
Query: 462 CRVRGAPPLQVQWFRQGSE--IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIF 519
C G P QV W + S + P +L++ +L +A P D+G +
Sbjct: 24 CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEG-----------SLFLASVSPADSGDY 72
Query: 520 TCSARNDYGSATSTAQLVV 538
C A N+ GS + A+LVV
Sbjct: 73 ECQATNEVGSTSRRAKLVV 91
Score = 35.4 bits (80), Expect = 0.30
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 5/98 (5%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F+++ + + G V C+ G P P I W + G+ + T+ DG+
Sbjct: 3117 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP---DGSLW 3173
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQ 873
L + D G Y +A N G + L+V+ Q
Sbjct: 3174 LENVET--GDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3209
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 125 bits (313), Expect = 3e-28
Identities = 196/871 (22%), Positives = 315/871 (36%), Gaps = 175/871 (20%)
Query: 286 SRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCL 345
S + LEC P P +RW+ +G+ + + +Q+ EG L I D+GRY C+
Sbjct: 2655 STLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEG---RLLQIQPTQVSDSGRYLCV 2711
Query: 346 ATNPSGSDTTSAEVFIE--------GASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTI 397
ATN +G D V I+ G S + S ++R G + + +
Sbjct: 2712 ATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 2771
Query: 398 GSSSP---------------KTGVTTAVIQP---LSVPVQQVHSPTSYLCRPDGTT---- 435
++ G +V+Q L +P+ + + Y C+
Sbjct: 2772 CDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDW 2831
Query: 436 -----TAYFPPVF---TKEL-QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
PPV T+EL + V V L+C G P + W + G SP
Sbjct: 2832 LHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPR 2891
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL-VVTSANTEN 545
++L+ + ++ T +A DA + C A N GSA L V
Sbjct: 2892 LQVLED-----GQVLQVSTAEVA-----DAASYMCVAENQAGSAEKLFTLRVQVPPRIAG 2941
Query: 546 CSYESMGESNNDHFQ-----HFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQ 600
E + N H P P E+ K S+ + E+ L
Sbjct: 2942 LDLEQVTAILNSSVSLPCDVHAHPNP--------EVTWYKDSQALSLGE-EVFLLPGTHT 2992
Query: 601 MQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKK 660
+Q A +G++ +N A ++ L +VL+ P P
Sbjct: 2993 LQLGRARLSDSGMYTCEALNA-----AGRDQKLVQLSVLVPPAFRQAP------------ 3035
Query: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATV 720
+G +DAV+ + K + +P +T+ + +L + +
Sbjct: 3036 -------------RGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL 3082
Query: 721 FNIQEPEEETANQEYK-VSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFF 779
Q E + A K + SC+ +S + +G+ V+ + V+ + P F
Sbjct: 3083 RGGQRLEIQEAQVSDKGLYSCK---VSNV-----------AGEAVRTFTLTVQ--VPPTF 3126
Query: 780 EM-KLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
E K + G P+ TC V+G P P + W KD + + H + R G L
Sbjct: 3127 ENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRG--GRLQLSR 3184
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
G YT +A N Q + V AV + PR RS
Sbjct: 3185 LQPA--QAGTYTCVAENTQAEAR---KDFVVAV---------------LVAPRIRSSGVA 3224
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD-SAH 957
E+ V EG+ R+DC+ G P PD++W DG P+ D H
Sbjct: 3225 REHH-------------------VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPH 3265
Query: 958 KMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNS--FSLELVVAAKEAHKPPVFIEK 1015
+ G SL+++ + + DAG YTC+A N AG+++ ++ ++V PP +
Sbjct: 3266 LRFYLDGG--SLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLV-------PPTIKQG 3316
Query: 1016 LQNTGVADGYP---VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQ 1072
+G P V + C V G PP + W K+ L S R +H H L I
Sbjct: 3317 ADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLS-QRTLLHGSGH---TLRIS 3372
Query: 1073 GATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
DAG +T A + AG+ L V +
Sbjct: 3373 KVQLADAGIFTCVAASPAGVADRNFTLQVQV 3403
Score = 115 bits (289), Expect = 2e-25
Identities = 198/909 (21%), Positives = 324/909 (35%), Gaps = 161/909 (17%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V E V L C G PTP + WF +G L + + ++ GG L + A D G
Sbjct: 1514 VMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKV-VYTRGG--RQLQLGRAQSSDAGV 1570
Query: 342 YTCLATNPSGS--DTTSAEVF----IEGASSTDSDSESLA-----FKSRAGAMPQAQKKT 390
YTC A+N G+ T +V+ IEGA +++A + A P
Sbjct: 1571 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSW 1630
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---RPDGTTTAYF------PP 441
L + S+ T + L P + S Y C P G + PP
Sbjct: 1631 HHEGLPVAESNESRLETDGSVLRLESPGEA--SSGLYSCVASSPAGEAVLQYSVEVQVPP 1688
Query: 442 --VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
+ + L GQ + L C+ G+P +QW + G ++ ++ +
Sbjct: 1689 QLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT----- 1743
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESN--ND 557
TL I + +G+F C A N+ G+A + ++ V +G+ + +
Sbjct: 1744 -----TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXE 1798
Query: 558 HFQHFP--------------PPPPILE-----------TSSLELASKKPS--EIQQVNNP 590
H FP P PP++E + + +A P +I++V+
Sbjct: 1799 HHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLR 1858
Query: 591 ELGLSRAALQMQFNAAERET--NGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPP 648
+ G+ A ++RE + P G +N N S+ + + PPP
Sbjct: 1859 DEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLA---SGVPPP 1915
Query: 649 LLAKPKLGFPKKA------SRTARIASDEEIQ----GTKDAVIQDLERKLRFKEDLLNNG 698
++ K P + S R+ E+ Q G+ V ++ + L N
Sbjct: 1916 DVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNV 1975
Query: 699 QPRLTYEE------------RMARRLLGADSATVFNIQE--PEEETANQEYKVSSCEQRL 744
PR+T R+ GA S T+ +++ P +V R+
Sbjct: 1976 PPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFP-GGRV 2034
Query: 745 ISEIEYRLERS------PVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTC 798
++ R S V G++ Q DV ++ M P + + + V C
Sbjct: 2035 LTLASARASDSGRYSCVAVSAVGEDRQ--DVVLQVHMPPSILGEELNVSVVANESVALEC 2092
Query: 799 RVAGNPKPKIYWFKDGKQISPKSD-HYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 857
+ P P + W+KDG+ + P+ H + + L L + + D G+YT A N
Sbjct: 2093 QSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-----LQVDRADVWDAGHYTCEALNQA 2147
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP 917
G L V +P P H
Sbjct: 2148 GHSEKHYNLNVWV------APVFPLRESHT------------------------------ 2171
Query: 918 GDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSR 977
LTV+EG + C+ G+P P +SW+ DG+P+ + A V G L +
Sbjct: 2172 --LTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVG-RLLYLGQAQLA 2228
Query: 978 DAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI---EKLQNTGVADGYPVRLECRVL 1034
G YTC +N G +S L+L E H PP E V LEC
Sbjct: 2229 QEGTYTCECSNVVGNSSQDLQL-----EVHVPPQIAGPREPPTQVSVVQDGVATLECNAT 2283
Query: 1035 GVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 1094
G PPP + W+++ + + + + N G L ++ A G Y+ A+N AG
Sbjct: 2284 GKPPPTVTWERDGQPV---GAELGLQLQNQGQ-SLHVERAQAAHTGRYSCVAENLAGRAE 2339
Query: 1095 CTARLDVYI 1103
L V +
Sbjct: 2340 RKFELSVLV 2348
Score = 111 bits (277), Expect = 4e-24
Identities = 191/924 (20%), Positives = 318/924 (34%), Gaps = 195/924 (21%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
+V +G +L C VTG+P P++ WF +G+ L I +G L L +A G
Sbjct: 2456 KVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVL---QANLSSAG 2512
Query: 341 RYTCLATNPSGSDTTS-------AEVFIEGASSTDSDS-------------ESLAFKS-- 378
Y+C+A N G T A + GA + + E+LAF S
Sbjct: 2513 HYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPN 2572
Query: 379 ----RAGAMPQAQKK------TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYL 428
+ GA +A + T + + T V L V+ H L
Sbjct: 2573 ITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYH--VEVL 2630
Query: 429 CRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
P + V KE++ + LEC PP ++W++ G + S +
Sbjct: 2631 IPPSISKDDPLGEVGVKEVKTKV---NSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQ 2687
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT--------- 539
+L + +P ++ D+G + C A N G +++
Sbjct: 2688 VLGEGRLLQIQPTQV----------SDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVG 2737
Query: 540 --SANTENCSYESMGESNNDHFQHFPPPPP---ILETSSL---ELASKKPSEIQQVNNPE 591
SA E S E ++ P +T+++ +L + + + E
Sbjct: 2738 DFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGD-E 2796
Query: 592 LGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKE------ 645
+ + + +Q E G + + N + + + TP V+L T+E
Sbjct: 2797 VSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVT 2856
Query: 646 ----------------PPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLR 689
P P ++ + G P S ++ D ++ A + D +
Sbjct: 2857 VNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMC 2916
Query: 690 FKEDLLNNGQPRLTYEERMARRLLGADSATVFNI--------------QEPEEETANQEY 735
E+ + + T ++ R+ G D V I PE
Sbjct: 2917 VAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ 2976
Query: 736 KVSSCEQRLISEIEYRLE--RSPVDESG------------DE--VQYGD-VPVENGMAPF 778
+S E+ + + L+ R+ + +SG D+ VQ VP AP
Sbjct: 2977 ALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPR 3036
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD--LDGTCSL 836
++ G +C P+P + W+KDG+ + QR L G L
Sbjct: 3037 GPQDAVLVRV--GDKAVLSCETDALPEPTVTWYKDGQPL------VLAQRTQALRGGQRL 3088
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
+ + D G Y+ +N G T L VQ
Sbjct: 3089 EIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQV-------------------------- 3122
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQE--GKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
P + P TV + G + C VSG+P P ++W D PV
Sbjct: 3123 --------------PPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESS 3168
Query: 955 SAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIE 1014
+ H ++ R + ++P AG YTC+A N Q + VVA A
Sbjct: 3169 AVHGVVSRGGRLQLSRLQPA---QAGTYTCVAENT--QAEARKDFVVAVLVA-------P 3216
Query: 1015 KLQNTGVA------DGYPVRLECRVLGVPPPQIFWKKENESLTHST-DRVSMHQDNHGYI 1067
+++++GVA +G VRL+C G PPP + W K+ L + + D
Sbjct: 3217 RIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGS-- 3274
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAG 1091
L+++G DAG YT A N AG
Sbjct: 3275 -LVLKGLRASDAGAYTCVAHNPAG 3297
Score = 98.6 bits (244), Expect = 3e-20
Identities = 86/324 (26%), Positives = 133/324 (41%), Gaps = 60/324 (18%)
Query: 775 MAPFFEMKLKH-YKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKS---DHYTIQRDL 830
+AP F ++ H + EG P + +C G P PKI W KDG+ + + H + L
Sbjct: 2160 VAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL 2219
Query: 831 DGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRP 890
L+ + L +G YT +N G S +L V P + P
Sbjct: 2220 -----LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVP-------------PQIAGP 2261
Query: 891 RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
R + P ++V + + ++C +G P P ++W+ DG+P
Sbjct: 2262 R-----------------------EPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQP 2298
Query: 951 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP 1010
V A L +N SL +E + G Y+C+A N AG+ EL V PP
Sbjct: 2299 V---GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLV-----PP 2350
Query: 1011 VFI---EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 1067
I + L N A P+ L C +G+PPP I W + E ++ D + G
Sbjct: 2351 ELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLL----AGGW 2406
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAG 1091
L + ++D+G Y+ A NEAG
Sbjct: 2407 MLKMTQTQEQDSGLYSCLASNEAG 2430
Score = 96.7 bits (239), Expect = 1e-19
Identities = 98/372 (26%), Positives = 137/372 (36%), Gaps = 81/372 (21%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G C +G P P++ W++ G ++ + + + L A+ D G YT
Sbjct: 712 GEEAVLVCEASGVPPPRVIWYRGGLEM-------ILAPEGSSSGKLRIPAAQERDAGTYT 764
Query: 851 IMAANPQGRISCT----------------------GRLMVQAVNQRGRSP-----RSPSG 883
A N G S GR + A GR P R G
Sbjct: 765 CRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDG 824
Query: 884 HP------HVRRPRSRSRDSG---------DENEP------------------IQERFFR 910
P R RSR DSG ++ P I
Sbjct: 825 QPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAP 884
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKV-SGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
P + + V EG+ + C V +G P P+ W DG+P+ P S H +R +G SL
Sbjct: 885 PQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHS--IRADG--SL 940
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
++ AG Y+C+ATN AG +ELVV PP + +G P L
Sbjct: 941 HLDRALQEHAGRYSCVATNTAGSQHRDVELVVQV-----PPRIHPTATHHITNEGVPASL 995
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
C GVP P I W KE +LT ++ ++ LLI + +DAG Y +A N
Sbjct: 996 PCVASGVPAPTITWTKETNALTSRGPHYNVSKEG----TLLIAQPSAQDAGAYVCTATNT 1051
Query: 1090 AGIVSCTARLDV 1101
G S RL V
Sbjct: 1052 VGFSSQEMRLSV 1063
Score = 95.5 bits (236), Expect = 2e-19
Identities = 85/299 (28%), Positives = 121/299 (40%), Gaps = 48/299 (16%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
P+T C G P P I WF+ + +SP D Y L G L T + D G Y+ +
Sbjct: 2369 PLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYL----LAGGWMLKMTQTQEQDSGLYSCL 2424
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A+N + G + R+ S V P S ENE ++E
Sbjct: 2425 ASN-----------------EAGEARRNFS--VEVLVPPSI------ENEDLEEV----- 2454
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
+ V +G+ + C V+G P P L+W DG+P+ AH + +GV +++
Sbjct: 2455 -------IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHH--ISPDGVLLQVLQ 2505
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
S AG Y+CIA N G+ + +L V + V P+ L C
Sbjct: 2506 ANLS-SAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICE 2564
Query: 1033 VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
L P P I W K+ S + + + HG L I A KEDAG YT NE G
Sbjct: 2565 ALAFPSPNITWMKDGAPFEASRN-IQLLPGTHG---LQILNAQKEDAGQYTCVVTNELG 2619
Score = 95.1 bits (235), Expect = 3e-19
Identities = 190/879 (21%), Positives = 308/879 (35%), Gaps = 141/879 (16%)
Query: 254 NRKSHPQPHSALHFPAAPRF-IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELH 312
N+ H + H L+ AP F +++ + V EG L C G P P++ W +G+ L
Sbjct: 2145 NQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLP 2204
Query: 313 NTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE---------- 362
H L + +A G YTC +N G+ + ++ +
Sbjct: 2205 GEGAGLQHVSAVG-RLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 2263
Query: 363 --GASSTDSDSESLAFKSRAGAMPQA---QKKTTSVSLTIGSSSPKTGVTTAVIQPLSVP 417
S D + + G P ++ V +G G Q L V
Sbjct: 2264 PPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG------QSLHVE 2317
Query: 418 VQQVHSPTSYLCRPDGTT---------TAYFPPVFTKELQ---NTAVAEGQVVVLECRVR 465
Q Y C + + PP +L N A + L C
Sbjct: 2318 RAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAM 2377
Query: 466 GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARN 525
G PP ++WFR + D +L L + +T +D+G+++C A N
Sbjct: 2378 GIPPPAIRWFRGEEPVSPGEDTYLLAGG----------WMLKMTQTQEQDSGLYSCLASN 2427
Query: 526 DYGSATSTAQL-VVTSANTENCSYESMGESNNDHFQHF-------PPPPPILETSSLELA 577
+ G A + V+ + EN E + + + H P P LA
Sbjct: 2428 EAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLA 2487
Query: 578 SKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPA 637
I +P+ G+ LQ ++A G + N + G+ + L +
Sbjct: 2488 RGDAHHI----SPD-GVLLQVLQANLSSA-----GHYSCIAANAV--GEKTKHFQL---S 2532
Query: 638 VLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNN 697
VLL+PT LG A ++DEE+ T + I + L F +
Sbjct: 2533 VLLAPT----------ILG-------GAEDSADEEVTVTVNNPISLICEALAFPSPNITW 2575
Query: 698 GQPRLTYE-ERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSP 756
+ +E R + L G + N Q +E+ V++ + + P
Sbjct: 2576 MKDGAPFEASRNIQLLPGTHGLQILNAQ--KEDAGQYTCVVTNELGEAVKNYHVEVLIPP 2633
Query: 757 VDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ 816
D + G+V V K K +T C P P I W+KDG+
Sbjct: 2634 SISKDDPL--GEVGV------------KEVKTKVNSTLTLECESWAVPPPTIRWYKDGQP 2679
Query: 817 ISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGR 876
++P S +Q +G L + + D G Y +A N G +++Q V +
Sbjct: 2680 VTPSS---RLQVLGEGRL-LQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ-VPPMFQ 2734
Query: 877 SPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSG 936
S + +R E I E P +L C +
Sbjct: 2735 KVGDFSAAFEILSREEEARGGVTEYREIVEN--NPAYLY----------------CDTNA 2776
Query: 937 LPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFS 996
+P PDL+W + +P+ +L G L I V + +AG Y+C A+N G++
Sbjct: 2777 IPPPDLTWYREDQPLSAGDEVSVL---QGGRVLQIPLVRAENAGRYSCKASNEVGEDWLH 2833
Query: 997 LELVVAAKEAHKPPVFI----EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTH 1052
EL+V PPV + E ++ V V L+C LG P P I W + +
Sbjct: 2834 YELLVLT-----PPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSP 2888
Query: 1053 STDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
S R+ + +D L + A DA Y A+N+AG
Sbjct: 2889 S-PRLQVLEDGQ---VLQVSTAEVADAASYMCVAENQAG 2923
Score = 92.4 bits (228), Expect = 2e-18
Identities = 97/380 (25%), Positives = 147/380 (38%), Gaps = 90/380 (23%)
Query: 784 KHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTL 843
+ + + EG V C G P P + W KDG + + ++ LDG SL
Sbjct: 3225 REHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPH-LRFYLDGG-SLVLKGLRA 3282
Query: 844 DDDGNYTIMAANPQGR-------------------------ISCTGRLMVQAVNQRGRSP 878
D G YT +A NP G +S G L+ RG P
Sbjct: 3283 SDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPP 3342
Query: 879 -------------------RSPSGHPHVRRPRSRSRDSG-------------DENEPIQE 906
SGH +R + + D+G D N +Q
Sbjct: 3343 IHVSWLKDGLPLPLSQRTLLHGSGHT-LRISKVQLADAGIFTCVAASPAGVADRNFTLQV 3401
Query: 907 RFFRPHFLQA---PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 963
+ P L+ D+ V G L + C+ G+P P +SW DG+P+ S E
Sbjct: 3402 QV--PPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL------E 3453
Query: 964 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT--GV 1021
G SL +E V + D+G Y+C+A + AG+ +L V +PP + Q T +
Sbjct: 3454 QG-PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVM-----EPPHIEDSGQPTELSL 3507
Query: 1022 ADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGW 1081
G P+ L C G P P I W K+ ++LT + ++ L ++ DAG
Sbjct: 3508 TPGAPMELLCDAQGTPQPNITWHKDGQALTR------LENNSRATRVLRVR-----DAGL 3556
Query: 1082 YTVSAKNEAGIVSCTARLDV 1101
YT A++ AG + + R+ V
Sbjct: 3557 YTCLAESPAGAIEKSFRVRV 3576
Score = 91.7 bits (226), Expect = 4e-18
Identities = 96/362 (26%), Positives = 148/362 (40%), Gaps = 51/362 (14%)
Query: 765 QYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHY 824
Q+ DV + + P H+ EG+P + C +G P P I W K+ ++ + HY
Sbjct: 964 QHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHY 1023
Query: 825 TIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRS---- 880
+ ++ GT L + D G Y A N G S RL +VN+ S
Sbjct: 1024 NVSKE--GT--LLIAQPSAQDAGAYVCTATNTVGFSSQEMRL---SVNRLALSKYVWEEY 1076
Query: 881 ---PSGHPHVRRPRSRSRDSGD----ENEPIQERFFR--------PHFLQAPGDLTVQEG 925
PSG +R + + DSG + P R P P L V G
Sbjct: 1077 GLLPSGS--LRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVG 1134
Query: 926 KLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCI 985
+ ++C G P P LSW DG ++ + VH + + DAG Y C
Sbjct: 1135 EALDLNCVAEGNPEPQLSWSKDGVVLQGRGP------QGSVH---FAAIRTSDAGRYRCE 1185
Query: 986 ATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVAD---GYPVRLECRVLGVPPPQIF 1042
A+N AG +++ +EL V +PP + + +G+ + G L C G P PQ+
Sbjct: 1186 ASNSAGVDAWEVELRVL-----EPPHWGAD-ETSGLLERVAGENASLPCPARGTPKPQVT 1239
Query: 1043 WKK-ENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
W+K + H V++ ++ L + + D+G Y A NE G S A+L V
Sbjct: 1240 WRKGPSSEPLHGQPGVAVLEEG----SLFLASVSPADSGDYECQATNEVGSTSRRAKLVV 1295
Query: 1102 YI 1103
Y+
Sbjct: 1296 YV 1297
Score = 91.7 bits (226), Expect = 4e-18
Identities = 85/317 (26%), Positives = 123/317 (38%), Gaps = 52/317 (16%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
+ E VT C +G P P + WFK G Q P S + +DG L + L D G
Sbjct: 1897 VLENASVTLECLASGVPPPDVSWFK-GHQ--PVSSWMGVTVSVDGRV-LRIEQAQLSDAG 1952
Query: 848 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 907
+Y +A+N G L V P + P S
Sbjct: 1953 SYRCVASNVAGSTELRYGLRVNVP-------------PRITLPPS--------------- 1984
Query: 908 FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
PG + V R+ C +G P+P L W DG PV P + V G
Sbjct: 1985 --------LPGPVLVNTP--VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGG-R 2033
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
L + + D+G Y+C+A + G++ + L V H PP + + N V V
Sbjct: 2034 VLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV-----HMPPSILGEELNVSVVANESV 2088
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 1087
LEC+ +PPP + W K+ L R +H + L + A DAG YT A
Sbjct: 2089 ALECQSHAMPPPVLSWWKDGRPL---EPRPGVHLSADKAL-LQVDRADVWDAGHYTCEAL 2144
Query: 1088 NEAGIVSCTARLDVYIS 1104
N+AG L+V+++
Sbjct: 2145 NQAGHSEKHYNLNVWVA 2161
Score = 90.1 bits (222), Expect = 1e-17
Identities = 94/369 (25%), Positives = 140/369 (37%), Gaps = 66/369 (17%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP + +G+ V +C +G P P I W ++ + + S I D GT
Sbjct: 607 APQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDS---RIHVDAQGTLI 663
Query: 836 LHTTASTLDDDGNYTIMAANPQGR--------------ISCTGRLMVQAVNQRGRSPRSP 881
+ A +D GNY+ A N G +S +++ AV +
Sbjct: 664 IQGVAP--EDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEA 721
Query: 882 SGHP-----------------------HVRRPRSRSRDSG-----------DENEPIQER 907
SG P +R P ++ RD+G D + IQ
Sbjct: 722 SGVPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLA 781
Query: 908 F-FRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL-DGKP--VRPDSAHKMLVRE 963
P + P D+TV+ G+ + C+ +G P P ++W+ DG+P +R + R+
Sbjct: 782 VGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQ 841
Query: 964 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVAD 1023
L E V D Y C A N G+ L+V H PP V +
Sbjct: 842 PDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVT---GHAPPQIASSAPTVRVLE 898
Query: 1024 GYPVRLECRVL-GVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
G PV L C VL G P P+ W K+ L + R S+ D L + A +E AG Y
Sbjct: 899 GQPVSLPCIVLAGRPLPERHWLKDGRPLPPGS-RHSIRADG----SLHLDRALQEHAGRY 953
Query: 1083 TVSAKNEAG 1091
+ A N AG
Sbjct: 954 SCVATNTAG 962
Score = 89.4 bits (220), Expect = 2e-17
Identities = 79/303 (26%), Positives = 118/303 (38%), Gaps = 64/303 (21%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P+ C G P+P I W KDG+ ++ ++ S T + D G YT
Sbjct: 3510 GAPMELLCDAQGTPQPNITWHKDGQALTRLENN-----------SRATRVLRVRDAGLYT 3558
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
+A +P G I + R+ VQA P++ PR
Sbjct: 3559 CLAESPAGAIEKSFRVRVQA-------------PPNIVGPRG------------------ 3587
Query: 911 PHFL--QAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS 968
P F+ APG L ++C V P P ++W DG ++ D AH
Sbjct: 3588 PRFVVGLAPGQLV--------LECSVEAEPAPKITWHRDGIVLQED-AHTQFPERG--RF 3636
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
L ++ +++ D+G Y+C A N AG S + + E H P V+
Sbjct: 3637 LQLQALSTADSGDYSCTARNAAGSTSVAFRV-----EIHTVPTIRSGPPAVNVSVNQTAL 3691
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L C+ GVP P + W+K+ L + R + + L IQ +DAG Y A N
Sbjct: 3692 LPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG----SLRIQPVLAQDAGHYLCLASN 3747
Query: 1089 EAG 1091
AG
Sbjct: 3748 SAG 3750
Score = 89.0 bits (219), Expect = 2e-17
Identities = 86/323 (26%), Positives = 123/323 (38%), Gaps = 71/323 (21%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ-------RD 829
P E L EG C+ G+P+P I W KDG+ +S +TIQ ++
Sbjct: 4038 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 4097
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889
L+G D G YT A N GR L + +
Sbjct: 4098 LEG-----------QDAGTYTCTAENAVGRARRRVHLTILVL------------------ 4128
Query: 890 PRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGK 949
P F PGD +++ G + C G PTP + W ++ +
Sbjct: 4129 ---------------------PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDR 4167
Query: 950 PVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP 1009
PV + + ++G +L V+ D+G Y C A NR G+ V KEA P
Sbjct: 4168 PVT-----EGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEA--P 4218
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
+ E G ++L+C V G P P I W K+ L S R HQ +G L
Sbjct: 4219 VLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLR---HQLQNG--SL 4273
Query: 1070 LIQGATKEDAGWYTVSAKNEAGI 1092
I ++DAG Y A+NE G+
Sbjct: 4274 TIHRTERDDAGRYQCLAENEMGV 4296
Score = 85.9 bits (211), Expect = 2e-16
Identities = 93/326 (28%), Positives = 121/326 (37%), Gaps = 61/326 (18%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDL-----------DGTCSLHTT 839
G +T C G P P+I W KD + + DL D SLH
Sbjct: 1315 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 1374
Query: 840 ASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGD 899
D G Y+ A N G L+V +P S G +G
Sbjct: 1375 RIQEGDSGLYSCRAENQAGTAQRDFHLLVL-------TPPSVLG-------------AGA 1414
Query: 900 ENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKM 959
E + A D+ +Q C SG+PTP + W D +PV P H +
Sbjct: 1415 AQEVLG---------LAGADVELQ--------CWTSGVPTPQVEWTKDRQPVLPGGPH-L 1456
Query: 960 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF--IEKLQ 1017
V+E+G L I D G Y C+A + AGQ + +L V H PP +
Sbjct: 1457 QVQEDG-QVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRV-----HAPPTIWGSNETG 1510
Query: 1018 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKE 1077
V + + V+L C GVP P I W K+ L ST V G L + A
Sbjct: 1511 EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVY----TRGGRQLQLGRAQSS 1566
Query: 1078 DAGWYTVSAKNEAGIVSCTARLDVYI 1103
DAG YT A N G RLDVY+
Sbjct: 1567 DAGVYTCKASNAVGAAEKATRLDVYV 1592
Score = 84.0 bits (206), Expect = 7e-16
Identities = 75/290 (25%), Positives = 115/290 (39%), Gaps = 36/290 (12%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP+ SQ ++G V + C +G PTP + W E + L I + +G TL
Sbjct: 607 APQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQG----TL 662
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKK 389
II +D G Y+C ATN G+D + ++ TD S S A + ++
Sbjct: 663 IIQGVAPEDAGNYSCQATNEVGTDQETVTLYY-----TDPPSVSAV---NAVVLVAVGEE 714
Query: 390 TTSVSLTIGSSSPKT----GVTTAVIQP-------LSVPVQQVHSPTSYLCRPD---GTT 435
V G P+ G ++ P L +P Q +Y CR G
Sbjct: 715 AVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDA 774
Query: 436 TAYF------PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRI 489
+A P T+ ++ V G+ +L CR G PP V W R + R+
Sbjct: 775 SAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQ---PLGLRL 831
Query: 490 LQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT 539
+ + +P+ L PED + C ARN +G + A+L+VT
Sbjct: 832 GAGRGSRSRQPDS-GVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVT 880
Score = 84.0 bits (206), Expect = 7e-16
Identities = 80/309 (25%), Positives = 126/309 (40%), Gaps = 65/309 (21%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G V C +G P P++ W KD + + P H +Q D L T S + D+G Y
Sbjct: 1423 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQ---VLRITGSHVGDEGRYQ 1479
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
+A +P G+ + +L V A P + G NE
Sbjct: 1480 CVAFSPAGQQARDFQLRVHA-------PPTIWG----------------SNET------- 1509
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
G++ V E L ++ C+ G+PTP+++W DG + P S + R G L
Sbjct: 1510 -------GEVAVMEDHLVQLLCEARGVPTPNITWFKDG-ALLPTSTKVVYTR--GGRQLQ 1559
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI-EKLQNTG-------VA 1022
+ S DAG+YTC A+N G AA++A + V++ ++ G
Sbjct: 1560 LGRAQSSDAGVYTCKASNAVG----------AAEKATRLDVYVPPTIEGAGGRPYVVKAV 1609
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
G PV LEC G P P + W E + S + + G + L ++ + +G Y
Sbjct: 1610 AGRPVALECVARGHPSPTLSWHHEGLPVAESNE---SRLETDGSV-LRLESPGEASSGLY 1665
Query: 1083 TVSAKNEAG 1091
+ A + AG
Sbjct: 1666 SCVASSPAG 1674
Score = 82.8 bits (203), Expect = 2e-15
Identities = 77/299 (25%), Positives = 113/299 (37%), Gaps = 56/299 (18%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
PV TC G P P + W K G Q+ + Y + + +L + G YT
Sbjct: 3873 PVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP----SGALEIGQALPIHAGRYTCS 3928
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A N G L VQA SP P P
Sbjct: 3929 ARNSAGVAHKHVFLTVQA---------SPVVKP------------------------LPS 3955
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
++A + V + C+ SG+P P ++WQ +G V + ++L L I
Sbjct: 3956 VVRAVAEEEVL------LPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ----LRIA 4005
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
+ DAG Y CIA N AG LVV PPV L + +G L C+
Sbjct: 4006 HASPEDAGNYLCIAKNSAGSAMGKTRLVVQV-----PPVIENGLPDLSTTEGSHAFLPCK 4060
Query: 1033 VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
G P P I W K+ + ++ + + ++ LL++ +DAG YT +A+N G
Sbjct: 4061 ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE----LLVKNLEGQDAGTYTCTAENAVG 4115
Score = 82.4 bits (202), Expect = 2e-15
Identities = 72/298 (24%), Positives = 113/298 (37%), Gaps = 58/298 (19%)
Query: 794 VTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMA 853
V C +G P+P I W K+G ++ + L ++ +D GNY +A
Sbjct: 3965 VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGG-----QLRIAHASPEDAGNYLCIA 4019
Query: 854 ANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHF 913
N G RL+VQ P +G P
Sbjct: 4020 KNSAGSAMGKTRLVVQV------PPVIENGLP---------------------------- 4045
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEP 973
DL+ EG + CK G P P+++W DG+PV + K ++ +G L+++
Sbjct: 4046 -----DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV-SGAEGKFTIQPSG--ELLVKN 4097
Query: 974 VTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRV 1033
+ +DAG YTC A N G+ + L + PVF + + G + L C
Sbjct: 4098 LEGQDAGTYTCTAENAVGRARRRVHLTILVL-----PVFTTLPGDRSLRLGDRLWLRCAA 4152
Query: 1034 LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
G P P+I W + +T + G L ++ED+G Y A+N G
Sbjct: 4153 RGSPTPRIGWTVNDRPVTEGV------SEQDGGSTLQRAAVSREDSGTYVCWAENRVG 4204
Score = 80.1 bits (196), Expect = 1e-14
Identities = 78/311 (25%), Positives = 114/311 (36%), Gaps = 59/311 (18%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G +CRV G + W +D + + + DL SL + D G Y
Sbjct: 531 GETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADL----SLEISGIIPTDGGRYQ 586
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
+A+N G + L+V+ Q S
Sbjct: 587 CVASNANGVTRASVWLLVREAPQVSIHTSSQ----------------------------- 617
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
HF Q G ++ C SG PTP +SW + + ++ DS + + +LI
Sbjct: 618 -HFSQ---------GVEVKVSCSASGYPTPHISWSRESQALQEDSR----IHVDAQGTLI 663
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 1030
I+ V DAG Y+C ATN G + ++ L PP VA G L
Sbjct: 664 IQGVAPEDAGNYSCQATNEVGTDQETVTLYYT-----DPPSVSAVNAVVLVAVGEEAVLV 718
Query: 1031 CRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1090
C GVPPP++ W + + + + S + L I A + DAG YT A NE
Sbjct: 719 CEASGVPPPRVIWYRGGLEMILAPEGSSSGK-------LRIPAAQERDAGTYTCRAVNEL 771
Query: 1091 GIVSCTARLDV 1101
G S +L V
Sbjct: 772 GDASAEIQLAV 782
Score = 77.8 bits (190), Expect = 5e-14
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 78/323 (24%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
+ G V C G P P + W KDG+ + + + L+ SL A D G
Sbjct: 3418 VVRGSLVELPCEARGVPLPLVSWMKDGEPL--------LSQSLEQGPSLQLEAVGAGDSG 3469
Query: 848 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 907
Y+ +A + G +L V PH+ DSG
Sbjct: 3470 TYSCVAVSEAGEARRHFQLTVME-------------PPHI-------EDSGQ-------- 3501
Query: 908 FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
P +L++ G + C G P P+++W DG+ + EN +
Sbjct: 3502 ---------PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQ--------ALTRLEN--N 3542
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---AHKPPVFIEKLQNTGVADG 1024
S + RDAG+YTC+A + AG S + V A + P F+ G+A G
Sbjct: 3543 SRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFV-----VGLAPG 3597
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI-----CLLIQGATKEDA 1079
V LEC V P P+I W + D + + +D H L +Q + D+
Sbjct: 3598 QLV-LECSVEAEPAPKITWHR---------DGIVLQEDAHTQFPERGRFLQLQALSTADS 3647
Query: 1080 GWYTVSAKNEAGIVSCTARLDVY 1102
G Y+ +A+N AG S R++++
Sbjct: 3648 GDYSCTARNAAGSTSVAFRVEIH 3670
Score = 75.5 bits (184), Expect = 3e-13
Identities = 60/181 (33%), Positives = 89/181 (49%), Gaps = 14/181 (7%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P + AP ++TV G+ + C+V G +L+W D + V P S + V + SL
Sbjct: 518 PQLVPAP-NVTVSPGETAVLSCRVLGEAPYNLTWVRDWR-VLPASTGR--VAQLADLSLE 573
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 1030
I + D G Y C+A+N G S+ L+V +EA P V I + + G V++
Sbjct: 574 ISGIIPTDGGRYQCVASNANGVTRASVWLLV--REA--PQVSIH-TSSQHFSQGVEVKVS 628
Query: 1031 CRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1090
C G P P I W +E+++L + +H D G L+IQG EDAG Y+ A NE
Sbjct: 629 CSASGYPTPHISWSRESQALQEDS---RIHVDAQG--TLIIQGVAPEDAGNYSCQATNEV 683
Query: 1091 G 1091
G
Sbjct: 684 G 684
Score = 74.3 bits (181), Expect = 6e-13
Identities = 86/370 (23%), Positives = 127/370 (34%), Gaps = 108/370 (29%)
Query: 787 KIFEGMPVTFTCRV-AGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDD 845
++ EG PV+ C V AG P P+ +W KDG+ + P S H +I+ D SLH + +
Sbjct: 895 RVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRH-SIRAD----GSLHLDRALQEH 949
Query: 846 DGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPR-SPSGHPHVRRPRSRSRDSGDENEPI 904
G Y+ +A N G L+VQ PR P+ H+
Sbjct: 950 AGRYSCVATNTAGSQHRDVELVVQV------PPRIHPTATHHI----------------- 986
Query: 905 QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 964
EG + C SG+P P ++W + + H + +E
Sbjct: 987 -----------------TNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEG 1029
Query: 965 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV----------------------- 1001
+L+I +++DAG Y C ATN G +S + L V
Sbjct: 1030 ---TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRL 1086
Query: 1002 ------------------AAKEAHK-------PPVFIEKLQNTGVADGYPVRLECRVLGV 1036
A +H+ PP + V G + L C G
Sbjct: 1087 AQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGN 1146
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
P PQ+ W K+ L + S+H DAG Y A N AG+ +
Sbjct: 1147 PEPQLSWSKDGVVLQGRGPQGSVH----------FAAIRTSDAGRYRCEASNSAGVDAWE 1196
Query: 1097 ARLDVYISRH 1106
L V H
Sbjct: 1197 VELRVLEPPH 1206
Score = 71.6 bits (174), Expect = 4e-12
Identities = 80/321 (24%), Positives = 118/321 (36%), Gaps = 58/321 (18%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
+ E V C G P P I WFKDG + P S R G L + D G
Sbjct: 1514 VMEDHLVQLLCEARGVPTPNITWFKDGALL-PTSTKVVYTR---GGRQLQLGRAQSSDAG 1569
Query: 848 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 907
YT A+N G RL V P + G
Sbjct: 1570 VYTCKASNAVGAAEKATRLDVYV-------------------PPTIEGAGG--------- 1601
Query: 908 FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
RP+ ++A G+ ++C G P+P LSW +G PV + ++ E
Sbjct: 1602 --RPYVVKAVA------GRPVALECVARGHPSPTLSWHHEGLPVAESNESRL---ETDGS 1650
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI--EKLQNTGVADGY 1025
L +E +G+Y+C+A++ AG+ + E PP + E L G
Sbjct: 1651 VLRLESPGEASSGLYSCVASSPAGEAVLQYSV-----EVQVPPQLLVAEGLGQVTTIVGQ 1705
Query: 1026 PVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVS 1085
P+ L C+ G P P I W + + + + + G L I + +G +
Sbjct: 1706 PLELPCQASGSPVPTIQWLQNGRP---AEELAGVQVASQG-TTLHIDHVELDHSGLFACQ 1761
Query: 1086 AKNEAGIVSCTARLDVYISRH 1106
A NEAG TA +V +S H
Sbjct: 1762 ATNEAG----TAGAEVEVSVH 1778
Score = 70.1 bits (170), Expect = 1e-11
Identities = 56/211 (26%), Positives = 87/211 (41%), Gaps = 48/211 (22%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G + C V G+P P I+W KDG + + +Q +G+ ++H T DD G Y
Sbjct: 4233 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ---NGSLTIHRTER--DDAGRYQ 4287
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
+A N G L++Q+
Sbjct: 4288 CLAENEMGVAKKVVILVLQSA--------------------------------------- 4308
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F P D+TV+ G + C+ +G PTP + W G+P+R ++ ++ +G SL
Sbjct: 4309 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLR--ASRRLRTLPDG--SLW 4364
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+E V + DAG Y C+A N G + LVV
Sbjct: 4365 LENVETGDAGTYDCVAHNLLGSATARAFLVV 4395
Score = 68.9 bits (167), Expect = 2e-11
Identities = 73/300 (24%), Positives = 114/300 (38%), Gaps = 63/300 (21%)
Query: 798 CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 857
C+ G P P + W KD + P+S + I + SL D G+Y +A+N
Sbjct: 3694 CQADGVPAPLVSWRKDRVPLDPRSPRFEILPE----GSLRIQPVLAQDAGHYLCLASNSA 3749
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP 917
G +++GR R V P P +P
Sbjct: 3750 GS------------DRQGRDLR-------VLEP--------------------PAIAPSP 3770
Query: 918 GDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR---PDSAHKMLVRENGVHSLIIEPV 974
+LT+ + C+ SG P P + W DG+ + A+++L ++L++
Sbjct: 3771 SNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPS----NALLLTAP 3826
Query: 975 TSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVL 1034
+D+ + C+ +N G+ ++ V H PP + + V PV L C
Sbjct: 3827 GPQDSAQFECVVSNEVGEAHRLYQVTV-----HVPPTIADDQTDFTVTMMAPVVLTCHST 3881
Query: 1035 GVPPPQIFWKKENESL--THSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGI 1092
G+P P + W K L S RVS L I A AG YT SA+N AG+
Sbjct: 3882 GIPAPTVSWSKAGAQLGARGSGYRVSPSG------ALEIGQALPIHAGRYTCSARNSAGV 3935
Score = 68.6 bits (166), Expect = 3e-11
Identities = 77/290 (26%), Positives = 109/290 (37%), Gaps = 53/290 (18%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT--PDIQIHCEGGDLHTLIIAEAF 335
R V EG V L+C G P P V W +G L P ++ + +GG +L++
Sbjct: 3225 REHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG---SLVLKGLR 3281
Query: 336 EDDTGRYTCLATNPSGSDTT--SAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSV 393
D G YTC+A NP+G D + V + +D S SR G + T V
Sbjct: 3282 ASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADG-SGTLVSRPGEL------VTMV 3334
Query: 394 SLTIGS-----SSPKTGVTTAVIQ---------PLSVPVQQVHSPTSYLC---RPDGTTT 436
GS S K G+ + Q L + Q+ + C P G
Sbjct: 3335 CPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD 3394
Query: 437 AYF------PPVFTK-ELQN-TAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
F PPV E QN V G +V L C RG P V W + G
Sbjct: 3395 RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDG---------- 3444
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+P + E+ +L + D+G ++C A ++ G A QL V
Sbjct: 3445 ----EPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTV 3490
Score = 65.1 bits (157), Expect = 4e-10
Identities = 85/313 (27%), Positives = 117/313 (37%), Gaps = 58/313 (18%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
P C +G+PKP + W+KDG+++ + L A L +
Sbjct: 3780 PALLPCEASGSPKPLVVWWKDGQKLDFR---------------LQQGAYRLLPSNALLLT 3824
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A PQ + + N+ G + R HV P + + D D
Sbjct: 3825 APGPQD----SAQFECVVSNEVGEAHRLYQVTVHV--PPTIADDQTDFTVT--------- 3869
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
+ AP LT C +G+P P +SW G + A R + +L I
Sbjct: 3870 -MMAPVVLT----------CHSTGIPAPTVSWSKAGAQL---GARGSGYRVSPSGALEIG 3915
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
AG YTC A N AG + L V A KP + + VA+ V L C
Sbjct: 3916 QALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVR----AVAEE-EVLLPCE 3970
Query: 1033 VLGVPPPQIFWKKE--NESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1090
G+P P I W+KE N + ST + Q L I A+ EDAG Y AKN A
Sbjct: 3971 ASGIPRPTITWQKEGLNVATGVSTQVLPGGQ-------LRIAHASPEDAGNYLCIAKNSA 4023
Query: 1091 GIVSCTARLDVYI 1103
G RL V +
Sbjct: 4024 GSAMGKTRLVVQV 4036
Score = 64.3 bits (155), Expect = 6e-10
Identities = 73/324 (22%), Positives = 120/324 (37%), Gaps = 40/324 (12%)
Query: 234 VKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECR 293
V+ G C ++ A+ + + Q + P PRF+ L A G V LEC
Sbjct: 3551 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGL-----APGQLV-LECS 3604
Query: 294 VTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSD 353
V P P++ W +G L Q G L ++ A D+G Y+C A N +GS
Sbjct: 3605 VEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTA---DSGDYSCTARNAAGST 3661
Query: 354 TTSAEVFIEGASSTDSD--------SESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTG 405
+ + V I + S +++ +A +P + + SP+
Sbjct: 3662 SVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPR-- 3719
Query: 406 VTTAVIQPLSVPVQQVHSPTS--YLC---------RPDGTTTAYFPPVFTKELQNTAVAE 454
++ S+ +Q V + + YLC R PP N +
Sbjct: 3720 --FEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA 3777
Query: 455 GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPE 514
+L C G+P V W++ G ++ DFR+ Q R L++ P+
Sbjct: 3778 HTPALLPCEASGSPKPLVVWWKDGQKL----DFRLQQGAYRLLPSN----ALLLTAPGPQ 3829
Query: 515 DAGIFTCSARNDYGSATSTAQLVV 538
D+ F C N+ G A Q+ V
Sbjct: 3830 DSAQFECVVSNEVGEAHRLYQVTV 3853
Score = 63.5 bits (153), Expect = 1e-09
Identities = 65/270 (24%), Positives = 96/270 (35%), Gaps = 37/270 (13%)
Query: 288 VYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLAT 347
V L C TG P P V W G +L G L I +A GRYTC A
Sbjct: 3874 VVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALE---IGQALPIHAGRYTCSAR 3930
Query: 348 NPSGSD------TTSAEVFIEGASSTDSD--SESLAFKSRAGAMPQAQKKTTSVSLTIGS 399
N +G T A ++ S E + A +P+ L +
Sbjct: 3931 NSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVA- 3989
Query: 400 SSPKTGVTTAVIQ--PLSVPVQQVHSPTSYLCRPDGTT---------TAYFPPVFTKELQ 448
TGV+T V+ L + +YLC + PPV L
Sbjct: 3990 ----TGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLP 4045
Query: 449 NTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVI 508
+ + EG L C+ RG+P + W + G + + + + T +P L++
Sbjct: 4046 DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGA--------EGKFTIQPSG--ELLV 4095
Query: 509 AETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+DAG +TC+A N G A L +
Sbjct: 4096 KNLEGQDAGTYTCTAENAVGRARRRVHLTI 4125
Score = 63.2 bits (152), Expect = 1e-09
Identities = 73/274 (26%), Positives = 109/274 (39%), Gaps = 30/274 (10%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V+ G L CRV G + W + + L + DL +L I+ D GR
Sbjct: 528 VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQL--ADL-SLEISGIIPTDGGR 584
Query: 342 YTCLATNPSGSDTTSAEVFIEGA------SSTDSDSESLAFKSRAGAM----PQAQKKTT 391
Y C+A+N +G S + + A +S+ S+ + K A P
Sbjct: 585 YQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRE 644
Query: 392 SVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHS--PTSYLCRPDGTTTAYF--PPVFTKEL 447
S +L S T +IQ ++ +S T+ + T T Y+ PP +
Sbjct: 645 SQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVN 704
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
VA G+ VL C G PP +V W+R G E+ IL + S+ + L
Sbjct: 705 AVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEM-------ILAPEGSSSGK------LR 751
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA 541
I DAG +TC A N+ G A++ QL V A
Sbjct: 752 IPAAQERDAGTYTCRAVNELGDASAEIQLAVGHA 785
Score = 63.2 bits (152), Expect = 1e-09
Identities = 59/198 (29%), Positives = 82/198 (41%), Gaps = 17/198 (8%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P+ P + V E ++C SG+P PD+SW +PV S + V +G L
Sbjct: 1886 PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMGVTVSVDG-RVLR 1942
Query: 971 IEPVTSRDAGIYTCIATNRAGQNS--FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
IE DAG Y C+A+N AG + L + V + P + L NT PVR
Sbjct: 1943 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNT------PVR 1996
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L C G P P + W K+ + S Q G L + A D+G Y+ A +
Sbjct: 1997 LTCNATGAPSPTLMWLKDGNPV--SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 2054
Query: 1089 EAGIVSCTARLDVYISRH 1106
G R DV + H
Sbjct: 2055 AVG----EDRQDVVLQVH 2068
Score = 60.1 bits (144), Expect = 1e-08
Identities = 62/290 (21%), Positives = 103/290 (35%), Gaps = 55/290 (18%)
Query: 280 QEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDT 339
+E+ E + YL C P P + W+ E + L ++ + +GG + + + A ++
Sbjct: 2760 REIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSV-LQGGRVLQIPLVRA--ENA 2816
Query: 340 GRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGS 399
GRY+C A+N G D E+ + D+E L ++ T + S T+
Sbjct: 2817 GRYSCKASNEVGEDWLHYELLVLTPPVILGDTEEL-----------VEEVTVNASSTVSL 2865
Query: 400 SSPKTGVTTAVI---------------------QPLSVPVQQVHSPTSYLCRPD---GTT 435
P G I Q L V +V SY+C + G+
Sbjct: 2866 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 2925
Query: 436 TAYF-------PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
F P + +L+ V L C V P +V W++ + +
Sbjct: 2926 EKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVF 2985
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+L TL + D+G++TC A N G QL V
Sbjct: 2986 LLPGTH----------TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSV 3025
Score = 60.1 bits (144), Expect = 1e-08
Identities = 112/468 (23%), Positives = 167/468 (35%), Gaps = 75/468 (16%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
VAE V L C +G P P + W EG + Q+ GG L IA A +D G
Sbjct: 3960 VAE-EEVLLPCEASGIPRPTITWQKEGLNVATGVSTQV-LPGGQLR---IAHASPEDAGN 4014
Query: 342 YTCLATNPSGSDTTSAEVFIE----------GASSTDSDSESLAFKSRAGAMPQA--QKK 389
Y C+A N +GS + ++ S+T+ L K+R P K
Sbjct: 4015 YLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKD 4074
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQP---LSVPVQQVHSPTSYLCRPDGTT---------TA 437
VS G + IQP L V + +Y C + T
Sbjct: 4075 GQPVSGAEGKFT---------IQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 4125
Query: 438 YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
PVFT + ++ G + L C RG+P ++ W + D P
Sbjct: 4126 LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGW-----TVNDRP-------VTEGV 4173
Query: 498 AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA---NTENCSY--ESMG 552
+E + TL A ED+G + C A N G + + + V A E SY E +G
Sbjct: 4174 SEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVG 4233
Query: 553 ES-NNDHFQHFPPPPPI--------LETSSLELASKKPS-EIQQVNNPELGLSRAALQMQ 602
S D P P I L S L + S I + + G + + +
Sbjct: 4234 GSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENE 4293
Query: 603 FNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKAS 662
A++ V S V + + + +S A+ T EP P + + G P +AS
Sbjct: 4294 MGVAKKVVILVLQSAPV-FQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRAS 4352
Query: 663 RTARIASDEEI---------QGTKDAVIQDLERKLRFKEDLLNNGQPR 701
R R D + GT D V +L + L+ G+P+
Sbjct: 4353 RRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 4400
Score = 58.9 bits (141), Expect = 3e-08
Identities = 57/268 (21%), Positives = 99/268 (36%), Gaps = 31/268 (11%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDD 338
++ V E + V LEC +G P P V WF + + + + + +G L I +A D
Sbjct: 1894 NKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG---RVLRIEQAQLSD 1950
Query: 339 TGRYTCLATNPSGSDTTSAEVFIE---GASSTDSDSESLAFKSRAGAMPQAQKKTTSVSL 395
G Y C+A+N +GS + + + S + + A + +
Sbjct: 1951 AGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLM 2010
Query: 396 TIGSSSPKTGVTTAVIQ------PLSVPVQQVHSPTSYLC---------RPDGTTTAYFP 440
+ +P + T +Q L++ + Y C R D + P
Sbjct: 2011 WLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMP 2070
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P E N +V + V LEC+ PP + W++ G ++ P + K +
Sbjct: 2071 PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDR 2130
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYG 528
++ DAG +TC A N G
Sbjct: 2131 ADVW----------DAGHYTCEALNQAG 2148
Score = 58.5 bits (140), Expect = 3e-08
Identities = 71/284 (25%), Positives = 94/284 (33%), Gaps = 47/284 (16%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
VA G L C +G P PRV W+ G E+ P EG L I A E D G
Sbjct: 709 VAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAP------EGSSSGKLRIPAAQERDAGT 762
Query: 342 YTCLATNPSGSDTTSAEVFIEGASS--------TDSDSESLAFKSRAGAMP-------QA 386
YTC A N G + ++ + A T S RA P +
Sbjct: 763 YTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRG 822
Query: 387 QKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT-----------T 435
+ + L G S + V+ SV + Y+C
Sbjct: 823 DGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPED---QAPYVCEARNVFGKVQAEARLIV 879
Query: 436 TAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPL-QVQWFRQGSEIQDSPDFRILQKKP 494
T + PP V EGQ V L C V PL + W + G + P
Sbjct: 880 TGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPL-----------PP 928
Query: 495 RSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
S +L + E AG ++C A N GS +LVV
Sbjct: 929 GSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVV 972
Score = 57.4 bits (137), Expect = 7e-08
Identities = 69/304 (22%), Positives = 107/304 (35%), Gaps = 36/304 (11%)
Query: 249 LAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAE--GSRVYLECRVTGNPTPRVRWFC 306
+ V N+ + L PR I L ++V S V L C V +P P V W+
Sbjct: 2915 MCVAENQAGSAEKLFTLRVQVPPR-IAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYK 2973
Query: 307 EGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI----- 361
+ + L ++ + HTL + A D+G YTC A N +G D ++ +
Sbjct: 2974 DSQALSLGEEVFLL---PGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPA 3030
Query: 362 ---EGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVI--QPLSV 416
D+ + K+ A + T G T A+ Q L +
Sbjct: 3031 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEI 3090
Query: 417 PVQQVHSPTSYLCRPDG---------TTTAYFPPVF-TKELQNTAVAEGQVVVLECRVRG 466
QV Y C+ T T PP F + + + G +VL C V G
Sbjct: 3091 QEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSG 3150
Query: 467 APPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARND 526
P V W + ++ S ++ + R L ++ P AG +TC A N
Sbjct: 3151 VPAPTVTWLKDRMPVESSAVHGVVSRGGR----------LQLSRLQPAQAGTYTCVAENT 3200
Query: 527 YGSA 530
A
Sbjct: 3201 QAEA 3204
Score = 57.0 bits (136), Expect = 1e-07
Identities = 72/310 (23%), Positives = 110/310 (35%), Gaps = 34/310 (10%)
Query: 249 LAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEG 308
L + N + L P L EGS +L C+ G+P P + W +G
Sbjct: 4016 LCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDG 4075
Query: 309 KELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASS 366
+ + G+ L++ D G YTC A N G + + +
Sbjct: 4076 QPVSGAEGKFTIQPSGE---LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFT 4132
Query: 367 TDSDSESLAFKSRAGAMPQAQ-KKTTSVSLTIGSSSPKTGVTT----AVIQPLSVPVQQV 421
T SL R A+ T + T+ GV+ + +Q +V +
Sbjct: 4133 TLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSRE-- 4190
Query: 422 HSPTSYLCRPDGTT--TAYFPPVFTKE---LQNTAVA-----EGQVVVLECRVRGAPPLQ 471
+Y+C + T V KE LQ A + G + L+C VRG P
Sbjct: 4191 -DSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPD 4249
Query: 472 VQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSAT 531
+ W + G ++ S LQ +L I T +DAG + C A N+ G A
Sbjct: 4250 IHWIKDGLPLRGSHLRHQLQNG-----------SLTIHRTERDDAGRYQCLAENEMGVAK 4298
Query: 532 STAQLVVTSA 541
LV+ SA
Sbjct: 4299 KVVILVLQSA 4308
Score = 56.2 bits (134), Expect = 2e-07
Identities = 42/138 (30%), Positives = 58/138 (42%), Gaps = 9/138 (6%)
Query: 962 RENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGV 1021
+E+G S I + + G Y C A +RAG ++VV PP + N V
Sbjct: 474 QESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVT-----DPPPQLVPAPNVTV 528
Query: 1022 ADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGW 1081
+ G L CRVLG P + W ++ L ST RV+ D + L I G D G
Sbjct: 529 SPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLAD----LSLEISGIIPTDGGR 584
Query: 1082 YTVSAKNEAGIVSCTARL 1099
Y A N G+ + L
Sbjct: 585 YQCVASNANGVTRASVWL 602
Score = 53.9 bits (128), Expect = 8e-07
Identities = 68/293 (23%), Positives = 104/293 (35%), Gaps = 62/293 (21%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELH-NTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
V+ L C+ G P P V W + L +P +I EG +L I D G
Sbjct: 3684 VSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG----SLRIQPVLAQDAG 3739
Query: 341 RYTCLATNPSGSDTTSAEVFI-------------------------EGASSTD------S 369
Y CLA+N +GSD ++ + E + S
Sbjct: 3740 HYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWK 3799
Query: 370 DSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC 429
D + L F+ + GA + S +L + + P+ + +S V + H
Sbjct: 3800 DGQKLDFRLQQGAY----RLLPSNALLLTAPGPQDSAQFECV--VSNEVGEAHRLYQ--- 3850
Query: 430 RPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEI-QDSPDFR 488
T + PP + + V VVL C G P V W + G+++ +R
Sbjct: 3851 -----VTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYR 3905
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA 541
+ P E I + P AG +TCSARN G A L V ++
Sbjct: 3906 V---SPSGALE--------IGQALPIHAGRYTCSARNSAGVAHKHVFLTVQAS 3947
Score = 51.6 bits (122), Expect = 4e-06
Identities = 70/288 (24%), Positives = 113/288 (39%), Gaps = 38/288 (13%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT-PDIQIHCEGGDLHTLIIAEAFE 336
R +V G + L C GNP P++ W +G L P +H A
Sbjct: 1127 RVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVH----------FAAIRT 1176
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFI-----EGASSTDSDSESLAFKSRAGAMPQAQKKTT 391
D GRY C A+N +G D E+ + GA T E +A ++ + P
Sbjct: 1177 SDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKP 1236
Query: 392 SVSLTIG-SSSPKTGVT-TAVIQPLSVPVQQVHSPTS--YLCRPD---GTTT------AY 438
V+ G SS P G AV++ S+ + V S Y C+ G+T+ Y
Sbjct: 1237 QVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVY 1296
Query: 439 FPPVFTKE--LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSP------DFRIL 490
PP ++ N + GQ + LEC G P ++ W + +++ P + +
Sbjct: 1297 VPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKD-AQLVGVPLGWAGYGWDLG 1355
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ +E +L D+G+++C A N G+A L+V
Sbjct: 1356 WGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLV 1403
Score = 51.2 bits (121), Expect = 5e-06
Identities = 70/291 (24%), Positives = 101/291 (34%), Gaps = 52/291 (17%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTP--------DI--------QIHCEGGDLHT 328
G + LEC G P P + W + +L P D+ ++ EG LH
Sbjct: 1315 GQSLTLECDANGFPVPEIVWLKDA-QLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHF 1373
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGA------ 382
I E D+G Y+C A N +G+ + + S + AGA
Sbjct: 1374 PRIQEG---DSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQC 1430
Query: 383 ----MPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---RPDGTT 435
+P Q + T + P V Q L + V Y C P G
Sbjct: 1431 WTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDG-QVLRITGSHVGDEGRYQCVAFSPAGQQ 1489
Query: 436 TAYF------PPVF--TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
F PP + E AV E +V L C RG P + WF+ G+ + S
Sbjct: 1490 ARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKV 1549
Query: 488 RILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ + R L + DAG++TC A N G+A +L V
Sbjct: 1550 -VYTRGGRQ---------LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDV 1590
Score = 48.9 bits (115), Expect = 3e-05
Identities = 63/282 (22%), Positives = 99/282 (35%), Gaps = 45/282 (15%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGK-----ELHNTPDIQIHCEGGDLHTLIIAEAFE 336
V GS V L C G P P V W +G+ L P +Q+ G
Sbjct: 3418 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAG----------- 3466
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQA---QKKTTSV 393
D+G Y+C+A + +G ++ + + + GA + + T
Sbjct: 3467 -DSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQP 3525
Query: 394 SLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---RPDGTTTAYF------PPVFT 444
++T +T + V +V Y C P G F PP
Sbjct: 3526 NITWHKDGQ--ALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIV 3583
Query: 445 KELQNTAV---AEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
V A GQ+V LEC V P ++ W R G +Q+ T PE
Sbjct: 3584 GPRGPRFVVGLAPGQLV-LECSVEAEPAPKITWHRDGIVLQEDAH----------TQFPE 3632
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT 543
L + D+G ++C+ARN GS + ++ + + T
Sbjct: 3633 RGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPT 3674
Score = 48.5 bits (114), Expect = 3e-05
Identities = 70/301 (23%), Positives = 106/301 (35%), Gaps = 48/301 (15%)
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
+H P P + + + V V LEC+ P P + W+ +G+ L P + +
Sbjct: 2067 VHMP--PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHL---SA 2121
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGS-------DTTSAEVFIEGASST----DSDSES 373
D L + A D G YTC A N +G + A VF S T + S
Sbjct: 2122 DKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTS 2181
Query: 374 LAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGV----TTAVIQPLSVPVQQVHSPTSYLC 429
L+ + R P+ + G P G +AV + L + Q+ +Y C
Sbjct: 2182 LSCECRGVPFPKISWRKD------GQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTC 2235
Query: 430 R---------PDGTTTAYFPPVFTKELQ---NTAVAEGQVVVLECRVRGAPPLQVQWFRQ 477
D + PP + +V + V LEC G PP V W R
Sbjct: 2236 ECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERD 2295
Query: 478 GSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLV 537
G + + LQ + +S L + G ++C A N G A +L
Sbjct: 2296 GQPVGAELGLQ-LQNQGQS---------LHVERAQAAHTGRYSCVAENLAGRAERKFELS 2345
Query: 538 V 538
V
Sbjct: 2346 V 2346
Score = 48.5 bits (114), Expect = 3e-05
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
+AP F + + V G V L C+ TG PTP + W G+ L + ++ +G +
Sbjct: 4307 SAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG----S 4362
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
L + D G Y C+A N GS T A + + G
Sbjct: 4363 LWLENVETGDAGTYDCVAHNLLGSATARAFLVVRG 4397
Score = 48.1 bits (113), Expect = 4e-05
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 5/95 (5%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRV-TGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
A P+ + V EG V L C V G P P W +G+ L I +G
Sbjct: 883 APPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADG---- 938
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+L + A ++ GRY+C+ATN +GS E+ ++
Sbjct: 939 SLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQ 973
Score = 46.6 bits (109), Expect = 1e-04
Identities = 66/308 (21%), Positives = 103/308 (33%), Gaps = 60/308 (19%)
Query: 237 PGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAA--------------PRFIQKLRSQEV 282
PG+RH + + L + + H +S + A PR
Sbjct: 928 PGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHIT 987
Query: 283 AEGSRVYLECRVTGNPTPRVRWFCEGKELHNT-PDIQIHCEGGDLHTLIIAEAFEDDTGR 341
EG L C +G P P + W E L + P + EG TL+IA+ D G
Sbjct: 988 NEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEG----TLLIAQPSAQDAGA 1043
Query: 342 YTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT-TSVSLTIGSS 400
Y C ATN G + + + + + E +G++ AQ + S +S
Sbjct: 1044 YVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLP-SGSLRLAQVQVGDSGHYECTAS 1102
Query: 401 SPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVL 460
+P + + + VP Q P + V G+ + L
Sbjct: 1103 NPAGSASHRYVLGVQVPPQVQPGP-----------------------RVLKVLVGEALDL 1139
Query: 461 ECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFT 520
C G P Q+ W + G +Q + P+ + I T DAG +
Sbjct: 1140 NCVAEGNPEPQLSWSKDGVVLQG--------RGPQGSVHFAAIRT--------SDAGRYR 1183
Query: 521 CSARNDYG 528
C A N G
Sbjct: 1184 CEASNSAG 1191
Score = 46.6 bits (109), Expect = 1e-04
Identities = 41/140 (29%), Positives = 58/140 (41%), Gaps = 13/140 (9%)
Query: 254 NRKSHPQPHSALHFPAAPRFIQKLRSQEVAE-GSRVYLECRVTGNPTPRVRWFCEGKELH 312
NR Q S +H AP + S V G + L+C V G+P P + W +G L
Sbjct: 4201 NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR 4260
Query: 313 NTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSD-------TTSAEVF-IEGA 364
+ ++ + G +L I DD GRY CLA N G SA VF +E
Sbjct: 4261 GS-HLRHQLQNG---SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQ 4316
Query: 365 SSTDSDSESLAFKSRAGAMP 384
T + +A + +A P
Sbjct: 4317 DMTVRSGDDVALRCQATGEP 4336
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 14/104 (13%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP N V+ G+ VL CRV G P + W R D+R+L P ST
Sbjct: 516 PPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVR---------DWRVL---PASTGR 563
Query: 500 PEEIC--TLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA 541
++ +L I+ P D G + C A N G ++ L+V A
Sbjct: 564 VAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREA 607
Score = 42.0 bits (97), Expect = 0.003
Identities = 62/308 (20%), Positives = 101/308 (32%), Gaps = 40/308 (12%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFC-EGKELHNTPDIQIHCEGG---- 324
AP+ + R V G L CR TG P P V W +G+ L +++ G
Sbjct: 785 APQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL----GLRLGAGRGSRSR 840
Query: 325 --DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGA 382
D L +D Y C A N G A + + G + S + + G
Sbjct: 841 QPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQ 900
Query: 383 -------------MPQAQKKTTSVSLTIGSSSPKTGVTTA----VIQPLSVPVQQVHSPT 425
+P+ L GS + +Q + V + T
Sbjct: 901 PVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNT 960
Query: 426 SYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQD-S 484
+ D PP + EG L C G P + W ++ + +
Sbjct: 961 AGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRG 1020
Query: 485 PDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTE 544
P + + ++ TL+IA+ +DAG + C+A N G ++ +L V
Sbjct: 1021 PHYNVSKEG-----------TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALS 1069
Query: 545 NCSYESMG 552
+E G
Sbjct: 1070 KYVWEEYG 1077
Score = 35.4 bits (80), Expect = 0.30
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 5/98 (5%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F+++ + + G V C+ G P P I W + G+ + T+ DG+
Sbjct: 4308 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP---DGSLW 4364
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQ 873
L + D G Y +A N G + L+V+ Q
Sbjct: 4365 LENVET--GDAGTYDCVAHNLLGSATARAFLVVRGEPQ 4400
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 125 bits (313), Expect = 3e-28
Identities = 196/871 (22%), Positives = 315/871 (36%), Gaps = 175/871 (20%)
Query: 286 SRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCL 345
S + LEC P P +RW+ +G+ + + +Q+ EG L I D+GRY C+
Sbjct: 1373 STLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEG---RLLQIQPTQVSDSGRYLCV 1429
Query: 346 ATNPSGSDTTSAEVFIE--------GASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTI 397
ATN +G D V I+ G S + S ++R G + + +
Sbjct: 1430 ATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLY 1489
Query: 398 GSSSP---------------KTGVTTAVIQP---LSVPVQQVHSPTSYLCRPDGTT---- 435
++ G +V+Q L +P+ + + Y C+
Sbjct: 1490 CDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDW 1549
Query: 436 -----TAYFPPVF---TKEL-QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
PPV T+EL + V V L+C G P + W + G SP
Sbjct: 1550 LHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPR 1609
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL-VVTSANTEN 545
++L+ + ++ T +A DA + C A N GSA L V
Sbjct: 1610 LQVLED-----GQVLQVSTAEVA-----DAASYMCVAENQAGSAEKLFTLRVQVPPRIAG 1659
Query: 546 CSYESMGESNNDHFQ-----HFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQ 600
E + N H P P E+ K S+ + E+ L
Sbjct: 1660 LDLEQVTAILNSSVSLPCDVHAHPNP--------EVTWYKDSQALSLGE-EVFLLPGTHT 1710
Query: 601 MQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKK 660
+Q A +G++ +N A ++ L +VL+ P P
Sbjct: 1711 LQLGRARLSDSGMYTCEALNA-----AGRDQKLVQLSVLVPPAFRQAP------------ 1753
Query: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATV 720
+G +DAV+ + K + +P +T+ + +L + +
Sbjct: 1754 -------------RGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL 1800
Query: 721 FNIQEPEEETANQEYK-VSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFF 779
Q E + A K + SC+ +S + +G+ V+ + V+ + P F
Sbjct: 1801 RGGQRLEIQEAQVSDKGLYSCK---VSNV-----------AGEAVRTFTLTVQ--VPPTF 1844
Query: 780 EM-KLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
E K + G P+ TC V+G P P + W KD + + H + R G L
Sbjct: 1845 ENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRG--GRLQLSR 1902
Query: 839 TASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSG 898
G YT +A N Q + V AV + PR RS
Sbjct: 1903 LQPA--QAGTYTCVAENTQAEAR---KDFVVAV---------------LVAPRIRSSGVA 1942
Query: 899 DENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD-SAH 957
E+ V EG+ R+DC+ G P PD++W DG P+ D H
Sbjct: 1943 REHH-------------------VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPH 1983
Query: 958 KMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNS--FSLELVVAAKEAHKPPVFIEK 1015
+ G SL+++ + + DAG YTC+A N AG+++ ++ ++V PP +
Sbjct: 1984 LRFYLDGG--SLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLV-------PPTIKQG 2034
Query: 1016 LQNTGVADGYP---VRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQ 1072
+G P V + C V G PP + W K+ L S R +H H L I
Sbjct: 2035 ADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLS-QRTLLHGSGH---TLRIS 2090
Query: 1073 GATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
DAG +T A + AG+ L V +
Sbjct: 2091 KVQLADAGIFTCVAASPAGVADRNFTLQVQV 2121
Score = 118 bits (295), Expect = 4e-26
Identities = 199/909 (21%), Positives = 325/909 (35%), Gaps = 161/909 (17%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V E V L C G PTP + WF +G L + + ++ GG L + A D G
Sbjct: 232 VMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKV-VYTRGG--RQLQLGRAQSSDAGV 288
Query: 342 YTCLATNPSGS--DTTSAEVF----IEGASSTDSDSESLA-----FKSRAGAMPQAQKKT 390
YTC A+N G+ T +V+ IEGA +++A + A P
Sbjct: 289 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSW 348
Query: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---RPDGTTTAYF------PP 441
L + S+ T + L P + S Y C P G + PP
Sbjct: 349 HHEGLPVAESNESRLETDGSVLRLESPGEA--SSGLYSCVASSPAGEAVLQYSVEVQVPP 406
Query: 442 --VFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
+ + L GQ + L C+ G+P +QW + G ++ ++ +
Sbjct: 407 QLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT----- 461
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESN--ND 557
TL I + +G+F C A N+ G+A + ++ V +G+ + +
Sbjct: 462 -----TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXE 516
Query: 558 HFQHFP--------------PPPPILE-----------TSSLELASKKPS--EIQQVNNP 590
H FP P PP++E + + +A P +I++V+
Sbjct: 517 HHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLR 576
Query: 591 ELGLSRAALQMQFNAAERET--NGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPP 648
+ G+ A ++RE + P G +N N S+ + + PPP
Sbjct: 577 DEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLA---SGVPPP 633
Query: 649 LLAKPKLGFPKKA------SRTARIASDEEIQ----GTKDAVIQDLERKLRFKEDLLNNG 698
++ K P + S R+ E+ Q G+ V ++ + L N
Sbjct: 634 DVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNV 693
Query: 699 QPRLTYEE------------RMARRLLGADSATVFNIQE--PEEETANQEYKVSSCEQRL 744
PR+T R+ GA S T+ +++ P +V R+
Sbjct: 694 PPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFP-GGRV 752
Query: 745 ISEIEYRLERS------PVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTC 798
++ R S V G++ Q DV ++ M P + + + V C
Sbjct: 753 LTLASARASDSGRYSCVAVSAVGEDRQ--DVVLQVHMPPSILGEELNVSVVANESVALEC 810
Query: 799 RVAGNPKPKIYWFKDGKQISPKSD-HYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 857
+ P P + W+KDG+ + P+ H + + L L + + D G+YT A N
Sbjct: 811 QSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL-----LQVDRADVWDAGHYTCEALNQA 865
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP 917
G L V +P P H
Sbjct: 866 GHSEKHYNLNVWV------APVFPLRESHT------------------------------ 889
Query: 918 GDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSR 977
LTV+EG R+ C+ G+P P +SW+ DG+P+ + A V G L +
Sbjct: 890 --LTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVG-RLLYLGQAQLA 946
Query: 978 DAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI---EKLQNTGVADGYPVRLECRVL 1034
G YTC +N G +S L+L E H PP E V LEC
Sbjct: 947 QEGTYTCECSNVVGNSSQDLQL-----EVHVPPQIAGPREPPTQVSVVQDGVATLECNAT 1001
Query: 1035 GVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVS 1094
G PPP + W+++ + + + + N G L ++ A G Y+ A+N AG
Sbjct: 1002 GKPPPTVTWERDGQPV---GAELGLQLQNQGQ-SLHVERAQAAHTGRYSCVAENLAGRAE 1057
Query: 1095 CTARLDVYI 1103
L V +
Sbjct: 1058 RKFELSVLV 1066
Score = 111 bits (278), Expect = 3e-24
Identities = 191/924 (20%), Positives = 318/924 (34%), Gaps = 195/924 (21%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
+V +G +L C VTG+P P++ WF +G+ L I +G L L +A G
Sbjct: 1174 KVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVL---QANLSSAG 1230
Query: 341 RYTCLATNPSGSDTTS-------AEVFIEGASSTDSDS-------------ESLAFKS-- 378
Y+C+A N G T A + GA + + E+LAF S
Sbjct: 1231 HYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPN 1290
Query: 379 ----RAGAMPQAQKK------TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYL 428
+ GA +A + T + + T V L V+ H L
Sbjct: 1291 ITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYH--VEVL 1348
Query: 429 CRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
P + V KE++ + LEC PP ++W++ G + S +
Sbjct: 1349 IPPSISKDDPLAEVGVKEVKTKV---NSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQ 1405
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT--------- 539
+L + +P ++ D+G + C A N G +++
Sbjct: 1406 VLGEGRLLQIQPTQV----------SDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVG 1455
Query: 540 --SANTENCSYESMGESNNDHFQHFPPPPP---ILETSSL---ELASKKPSEIQQVNNPE 591
SA E S E ++ P +T+++ +L + + + E
Sbjct: 1456 DFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGD-E 1514
Query: 592 LGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKE------ 645
+ + + +Q E G + + N + + + TP V+L T+E
Sbjct: 1515 VSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVT 1574
Query: 646 ----------------PPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLR 689
P P ++ + G P S ++ D ++ A + D +
Sbjct: 1575 VNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMC 1634
Query: 690 FKEDLLNNGQPRLTYEERMARRLLGADSATVFNI--------------QEPEEETANQEY 735
E+ + + T ++ R+ G D V I PE
Sbjct: 1635 VAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQ 1694
Query: 736 KVSSCEQRLISEIEYRLE--RSPVDESG------------DE--VQYGD-VPVENGMAPF 778
+S E+ + + L+ R+ + +SG D+ VQ VP AP
Sbjct: 1695 ALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPR 1754
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRD--LDGTCSL 836
++ G +C P+P + W+KDG+ + QR L G L
Sbjct: 1755 GPQDAVLVRV--GDKAVLSCETDALPEPTVTWYKDGQPL------VLAQRTQALRGGQRL 1806
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
+ + D G Y+ +N G T L VQ
Sbjct: 1807 EIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQV-------------------------- 1840
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQE--GKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
P + P TV + G + C VSG+P P ++W D PV
Sbjct: 1841 --------------PPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESS 1886
Query: 955 SAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIE 1014
+ H ++ R + ++P AG YTC+A N Q + VVA A
Sbjct: 1887 AVHGVVSRGGRLQLSRLQPA---QAGTYTCVAENT--QAEARKDFVVAVLVA-------P 1934
Query: 1015 KLQNTGVA------DGYPVRLECRVLGVPPPQIFWKKENESLTHST-DRVSMHQDNHGYI 1067
+++++GVA +G VRL+C G PPP + W K+ L + + D
Sbjct: 1935 RIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGS-- 1992
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAG 1091
L+++G DAG YT A N AG
Sbjct: 1993 -LVLKGLRASDAGAYTCVAHNPAG 2015
Score = 97.8 bits (242), Expect = 5e-20
Identities = 86/324 (26%), Positives = 132/324 (40%), Gaps = 60/324 (18%)
Query: 775 MAPFFEMKLKH-YKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKS---DHYTIQRDL 830
+AP F ++ H + EG P +C G P PKI W KDG+ + + H + L
Sbjct: 878 VAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL 937
Query: 831 DGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRP 890
L+ + L +G YT +N G S +L V P + P
Sbjct: 938 -----LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVP-------------PQIAGP 979
Query: 891 RSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
R + P ++V + + ++C +G P P ++W+ DG+P
Sbjct: 980 R-----------------------EPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQP 1016
Query: 951 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP 1010
V A L +N SL +E + G Y+C+A N AG+ EL V PP
Sbjct: 1017 V---GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLV-----PP 1068
Query: 1011 VFI---EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 1067
I + L N A P+ L C +G+PPP I W + E ++ D + G
Sbjct: 1069 ELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLL----AGGW 1124
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAG 1091
L + ++D+G Y+ A NEAG
Sbjct: 1125 MLKMTQTQEQDSGLYSCLASNEAG 1148
Score = 95.5 bits (236), Expect = 2e-19
Identities = 85/299 (28%), Positives = 121/299 (40%), Gaps = 48/299 (16%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
P+T C G P P I WF+ + +SP D Y L G L T + D G Y+ +
Sbjct: 1087 PLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYL----LAGGWMLKMTQTQEQDSGLYSCL 1142
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A+N + G + R+ S V P S ENE ++E
Sbjct: 1143 ASN-----------------EAGEARRNFS--VEVLVPPSI------ENEDLEEV----- 1172
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
+ V +G+ + C V+G P P L+W DG+P+ AH + +GV +++
Sbjct: 1173 -------IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHH--ISPDGVLLQVLQ 1223
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
S AG Y+CIA N G+ + +L V + V P+ L C
Sbjct: 1224 ANLS-SAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICE 1282
Query: 1033 VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
L P P I W K+ S + + + HG L I A KEDAG YT NE G
Sbjct: 1283 ALAFPSPNITWMKDGAPFEASRN-IQLLPGTHG---LQILNAQKEDAGQYTCVVTNELG 1337
Score = 92.4 bits (228), Expect = 2e-18
Identities = 97/380 (25%), Positives = 147/380 (38%), Gaps = 90/380 (23%)
Query: 784 KHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTL 843
+ + + EG V C G P P + W KDG + + ++ LDG SL
Sbjct: 1943 REHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPH-LRFYLDGG-SLVLKGLRA 2000
Query: 844 DDDGNYTIMAANPQGR-------------------------ISCTGRLMVQAVNQRGRSP 878
D G YT +A NP G +S G L+ RG P
Sbjct: 2001 SDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPP 2060
Query: 879 -------------------RSPSGHPHVRRPRSRSRDSG-------------DENEPIQE 906
SGH +R + + D+G D N +Q
Sbjct: 2061 IHVSWLKDGLPLPLSQRTLLHGSGHT-LRISKVQLADAGIFTCVAASPAGVADRNFTLQV 2119
Query: 907 RFFRPHFLQA---PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 963
+ P L+ D+ V G L + C+ G+P P +SW DG+P+ S E
Sbjct: 2120 QV--PPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL------E 2171
Query: 964 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT--GV 1021
G SL +E V + D+G Y+C+A + AG+ +L V +PP + Q T +
Sbjct: 2172 QG-PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVM-----EPPHIEDSGQPTELSL 2225
Query: 1022 ADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGW 1081
G P+ L C G P P I W K+ ++LT + ++ L ++ DAG
Sbjct: 2226 TPGAPMELLCDAQGTPQPNITWHKDGQALTR------LENNSRATRVLRVR-----DAGL 2274
Query: 1082 YTVSAKNEAGIVSCTARLDV 1101
YT A++ AG + + R+ V
Sbjct: 2275 YTCLAESPAGAIEKSFRVRV 2294
Score = 89.4 bits (220), Expect = 2e-17
Identities = 79/303 (26%), Positives = 118/303 (38%), Gaps = 64/303 (21%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G P+ C G P+P I W KDG+ ++ ++ S T + D G YT
Sbjct: 2228 GAPMELLCDAQGTPQPNITWHKDGQALTRLENN-----------SRATRVLRVRDAGLYT 2276
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
+A +P G I + R+ VQA P++ PR
Sbjct: 2277 CLAESPAGAIEKSFRVRVQA-------------PPNIVGPRG------------------ 2305
Query: 911 PHFL--QAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS 968
P F+ APG L ++C V P P ++W DG ++ D AH
Sbjct: 2306 PRFVVGLAPGQLV--------LECSVEAEPAPKITWHRDGIVLQED-AHTQFPERG--RF 2354
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
L ++ +++ D+G Y+C A N AG S + + E H P V+
Sbjct: 2355 LQLQALSTADSGDYSCTARNAAGSTSVAFRV-----EIHTVPTIRSGPPAVNVSVNQTAL 2409
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L C+ GVP P + W+K+ L + R + + L IQ +DAG Y A N
Sbjct: 2410 LPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG----SLRIQPVLAQDAGHYLCLASN 2465
Query: 1089 EAG 1091
AG
Sbjct: 2466 SAG 2468
Score = 89.4 bits (220), Expect = 2e-17
Identities = 86/323 (26%), Positives = 124/323 (38%), Gaps = 71/323 (21%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ-------RD 829
P E L EG C+ G+P+P I W KDG+ +S +TIQ ++
Sbjct: 2756 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 2815
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889
L+G D G YT A N GR L + +
Sbjct: 2816 LEG-----------QDAGTYTCTAENAVGRARRRVHLTILVL------------------ 2846
Query: 890 PRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGK 949
P F PGD +++ G + C G PTP + W ++ +
Sbjct: 2847 ---------------------PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDR 2885
Query: 950 PVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP 1009
PV + + ++G +L V+ D+G Y C A NR G+ V KEA P
Sbjct: 2886 PVT-----EGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRT--QAVSFVHVKEA--P 2936
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
+ E G ++L+C V G P P I W K+ L S R HQ +G L
Sbjct: 2937 VLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLR---HQLQNG--SL 2991
Query: 1070 LIQGATKEDAGWYTVSAKNEAGI 1092
I+ ++DAG Y A+NE G+
Sbjct: 2992 TIRRTERDDAGRYQCLAENEMGV 3014
Score = 85.9 bits (211), Expect = 2e-16
Identities = 93/326 (28%), Positives = 121/326 (37%), Gaps = 61/326 (18%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDL-----------DGTCSLHTT 839
G +T C G P P+I W KD + + DL D SLH
Sbjct: 33 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 92
Query: 840 ASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGD 899
D G Y+ A N G L+V +P S G +G
Sbjct: 93 RIQEGDSGLYSCRAENQAGTAQRDFHLLVL-------TPPSVLG-------------AGA 132
Query: 900 ENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKM 959
E + A D+ +Q C SG+PTP + W D +PV P H +
Sbjct: 133 AQEVLG---------LAGADVELQ--------CWTSGVPTPQVEWTKDRQPVLPGGPH-L 174
Query: 960 LVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVF--IEKLQ 1017
V+E+G L I D G Y C+A + AGQ + +L V H PP +
Sbjct: 175 QVQEDG-QVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRV-----HAPPTIWGSNETG 228
Query: 1018 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKE 1077
V + + V+L C GVP P I W K+ L ST V G L + A
Sbjct: 229 EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVY----TRGGRQLQLGRAQSS 284
Query: 1078 DAGWYTVSAKNEAGIVSCTARLDVYI 1103
DAG YT A N G RLDVY+
Sbjct: 285 DAGVYTCKASNAVGAAEKATRLDVYV 310
Score = 84.0 bits (206), Expect = 7e-16
Identities = 80/309 (25%), Positives = 126/309 (40%), Gaps = 65/309 (21%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G V C +G P P++ W KD + + P H +Q D L T S + D+G Y
Sbjct: 141 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQ---VLRITGSHVGDEGRYQ 197
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
+A +P G+ + +L V A P + G NE
Sbjct: 198 CVAFSPAGQQARDFQLRVHA-------PPTIWG----------------SNET------- 227
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
G++ V E L ++ C+ G+PTP+++W DG + P S + R G L
Sbjct: 228 -------GEVAVMEDHLVQLLCEARGVPTPNITWFKDG-ALLPTSTKVVYTR--GGRQLQ 277
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI-EKLQNTG-------VA 1022
+ S DAG+YTC A+N G AA++A + V++ ++ G
Sbjct: 278 LGRAQSSDAGVYTCKASNAVG----------AAEKATRLDVYVPPTIEGAGGRPYVVKAV 327
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
G PV LEC G P P + W E + S + + G + L ++ + +G Y
Sbjct: 328 AGRPVALECVARGHPSPTLSWHHEGLPVAESNE---SRLETDGSV-LRLESPGEASSGLY 383
Query: 1083 TVSAKNEAG 1091
+ A + AG
Sbjct: 384 SCVASSPAG 392
Score = 82.8 bits (203), Expect = 2e-15
Identities = 77/299 (25%), Positives = 113/299 (37%), Gaps = 56/299 (18%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
PV TC G P P + W K G Q+ + Y + + +L + G YT
Sbjct: 2591 PVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSP----SGALEIGQALPIHAGRYTCS 2646
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A N G L VQA SP P P
Sbjct: 2647 ARNSAGVAHKHVFLTVQA---------SPVVKP------------------------LPS 2673
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
++A + V + C+ SG+P P ++WQ +G V + ++L L I
Sbjct: 2674 VVRAVAEEEVL------LPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQ----LRIA 2723
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
+ DAG Y CIA N AG LVV PPV L + +G L C+
Sbjct: 2724 HASPEDAGNYLCIAKNSAGSAMGKTRLVVQV-----PPVIENGLPDLSTTEGSHAFLPCK 2778
Query: 1033 VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
G P P I W K+ + ++ + + ++ LL++ +DAG YT +A+N G
Sbjct: 2779 ARGSPEPNITWDKDGQPVSGAEGKFTIQPSGE----LLVKNLEGQDAGTYTCTAENAVG 2833
Score = 82.4 bits (202), Expect = 2e-15
Identities = 72/298 (24%), Positives = 113/298 (37%), Gaps = 58/298 (19%)
Query: 794 VTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMA 853
V C +G P+P I W K+G ++ + L ++ +D GNY +A
Sbjct: 2683 VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGG-----QLRIAHASPEDAGNYLCIA 2737
Query: 854 ANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHF 913
N G RL+VQ P +G P
Sbjct: 2738 KNSAGSAMGKTRLVVQV------PPVIENGLP---------------------------- 2763
Query: 914 LQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEP 973
DL+ EG + CK G P P+++W DG+PV + K ++ +G L+++
Sbjct: 2764 -----DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV-SGAEGKFTIQPSG--ELLVKN 2815
Query: 974 VTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRV 1033
+ +DAG YTC A N G+ + L + PVF + + G + L C
Sbjct: 2816 LEGQDAGTYTCTAENAVGRARRRVHLTILVL-----PVFTTLPGDRSLRLGDRLWLRCAA 2870
Query: 1034 LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
G P P+I W + +T + G L ++ED+G Y A+N G
Sbjct: 2871 RGSPTPRIGWTVNDRPVTEGV------SEQDGGSTLQRAAVSREDSGTYVCWAENRVG 2922
Score = 77.8 bits (190), Expect = 5e-14
Identities = 80/323 (24%), Positives = 125/323 (38%), Gaps = 78/323 (24%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
+ G V C G P P + W KDG+ + + + L+ SL A D G
Sbjct: 2136 VVRGSLVELPCEARGVPLPLVSWMKDGEPL--------LSQSLEQGPSLQLEAVGAGDSG 2187
Query: 848 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 907
Y+ +A + G +L V PH+ DSG
Sbjct: 2188 TYSCVAVSEAGEARRHFQLTVME-------------PPHI-------EDSGQ-------- 2219
Query: 908 FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
P +L++ G + C G P P+++W DG+ + EN +
Sbjct: 2220 ---------PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQ--------ALTRLEN--N 2260
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE---AHKPPVFIEKLQNTGVADG 1024
S + RDAG+YTC+A + AG S + V A + P F+ G+A G
Sbjct: 2261 SRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFV-----VGLAPG 2315
Query: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI-----CLLIQGATKEDA 1079
V LEC V P P+I W + D + + +D H L +Q + D+
Sbjct: 2316 QLV-LECSVEAEPAPKITWHR---------DGIVLQEDAHTQFPERGRFLQLQALSTADS 2365
Query: 1080 GWYTVSAKNEAGIVSCTARLDVY 1102
G Y+ +A+N AG S R++++
Sbjct: 2366 GDYSCTARNAAGSTSVAFRVEIH 2388
Score = 71.6 bits (174), Expect = 4e-12
Identities = 80/321 (24%), Positives = 118/321 (36%), Gaps = 58/321 (18%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
+ E V C G P P I WFKDG + P S R G L + D G
Sbjct: 232 VMEDHLVQLLCEARGVPTPNITWFKDGALL-PTSTKVVYTR---GGRQLQLGRAQSSDAG 287
Query: 848 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 907
YT A+N G RL V P + G
Sbjct: 288 VYTCKASNAVGAAEKATRLDVYV-------------------PPTIEGAGG--------- 319
Query: 908 FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
RP+ ++A G+ ++C G P+P LSW +G PV + ++ E
Sbjct: 320 --RPYVVKAVA------GRPVALECVARGHPSPTLSWHHEGLPVAESNESRL---ETDGS 368
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI--EKLQNTGVADGY 1025
L +E +G+Y+C+A++ AG+ + E PP + E L G
Sbjct: 369 VLRLESPGEASSGLYSCVASSPAGEAVLQYSV-----EVQVPPQLLVAEGLGQVTTIVGQ 423
Query: 1026 PVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVS 1085
P+ L C+ G P P I W + + + + + G L I + +G +
Sbjct: 424 PLELPCQASGSPVPTIQWLQNGRP---AEELAGVQVASQG-TTLHIDHVELDHSGLFACQ 479
Query: 1086 AKNEAGIVSCTARLDVYISRH 1106
A NEAG TA +V +S H
Sbjct: 480 ATNEAG----TAGAEVEVSVH 496
Score = 68.9 bits (167), Expect = 2e-11
Identities = 73/300 (24%), Positives = 114/300 (38%), Gaps = 63/300 (21%)
Query: 798 CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQ 857
C+ G P P + W KD + P+S + I + SL D G+Y +A+N
Sbjct: 2412 CQADGVPAPLVSWRKDRVPLDPRSPRFEILPE----GSLRIQPVLAQDAGHYLCLASNSA 2467
Query: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP 917
G +++GR R V P P +P
Sbjct: 2468 GS------------DRQGRDLR-------VLEP--------------------PAIAPSP 2488
Query: 918 GDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR---PDSAHKMLVRENGVHSLIIEPV 974
+LT+ + C+ SG P P + W DG+ + A+++L ++L++
Sbjct: 2489 SNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPS----NALLLTAP 2544
Query: 975 TSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVL 1034
+D+ + C+ +N G+ ++ V H PP + + V PV L C
Sbjct: 2545 GPQDSAQFECVVSNEVGEAHRLYQVTV-----HVPPTIADDQTDFTVTMMAPVVLTCHST 2599
Query: 1035 GVPPPQIFWKKENESL--THSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGI 1092
G+P P + W K L S RVS L I A AG YT SA+N AG+
Sbjct: 2600 GIPAPTVSWSKAGAQLGARGSGYRVSPSG------ALEIGQALPIHAGRYTCSARNSAGV 2653
Score = 68.6 bits (166), Expect = 3e-11
Identities = 77/290 (26%), Positives = 109/290 (37%), Gaps = 53/290 (18%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT--PDIQIHCEGGDLHTLIIAEAF 335
R V EG V L+C G P P V W +G L P ++ + +GG +L++
Sbjct: 1943 REHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG---SLVLKGLR 1999
Query: 336 EDDTGRYTCLATNPSGSDTT--SAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSV 393
D G YTC+A NP+G D + V + +D S SR G + T V
Sbjct: 2000 ASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADG-SGTLVSRPGEL------VTMV 2052
Query: 394 SLTIGS-----SSPKTGVTTAVIQ---------PLSVPVQQVHSPTSYLC---RPDGTTT 436
GS S K G+ + Q L + Q+ + C P G
Sbjct: 2053 CPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD 2112
Query: 437 AYF------PPVFTK-ELQN-TAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
F PPV E QN V G +V L C RG P V W + G
Sbjct: 2113 RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDG---------- 2162
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+P + E+ +L + D+G ++C A ++ G A QL V
Sbjct: 2163 ----EPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTV 2208
Score = 67.0 bits (162), Expect = 9e-11
Identities = 55/211 (26%), Positives = 86/211 (40%), Gaps = 48/211 (22%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G + C V G+P P I+W KDG + + +Q +G+ ++ T DD G Y
Sbjct: 2951 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQ---NGSLTIRRTER--DDAGRYQ 3005
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
+A N G L++Q+
Sbjct: 3006 CLAENEMGVAKKVVILVLQSA--------------------------------------- 3026
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F P D+TV+ G + C+ +G PTP + W G+P+R ++ ++ +G SL
Sbjct: 3027 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLR--ASRRLRTLPDG--SLW 3082
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+E V + DAG Y C+A N G + LVV
Sbjct: 3083 LENVETGDAGTYDCVAHNLLGSATARAFLVV 3113
Score = 65.1 bits (157), Expect = 4e-10
Identities = 85/313 (27%), Positives = 117/313 (37%), Gaps = 58/313 (18%)
Query: 793 PVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
P C +G+PKP + W+KDG+++ + L A L +
Sbjct: 2498 PALLPCEASGSPKPLVVWWKDGQKLDFR---------------LQQGAYRLLPSNALLLT 2542
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A PQ + + N+ G + R HV P + + D D
Sbjct: 2543 APGPQD----SAQFECVVSNEVGEAHRLYQVTVHV--PPTIADDQTDFTVT--------- 2587
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
+ AP LT C +G+P P +SW G + A R + +L I
Sbjct: 2588 -MMAPVVLT----------CHSTGIPAPTVSWSKAGAQL---GARGSGYRVSPSGALEIG 2633
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR 1032
AG YTC A N AG + L V A KP + + VA+ V L C
Sbjct: 2634 QALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVR----AVAEE-EVLLPCE 2688
Query: 1033 VLGVPPPQIFWKKE--NESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1090
G+P P I W+KE N + ST + Q L I A+ EDAG Y AKN A
Sbjct: 2689 ASGIPRPTITWQKEGLNVATGVSTQVLPGGQ-------LRIAHASPEDAGNYLCIAKNSA 2741
Query: 1091 GIVSCTARLDVYI 1103
G RL V +
Sbjct: 2742 GSAMGKTRLVVQV 2754
Score = 64.3 bits (155), Expect = 6e-10
Identities = 73/324 (22%), Positives = 120/324 (37%), Gaps = 40/324 (12%)
Query: 234 VKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECR 293
V+ G C ++ A+ + + Q + P PRF+ L A G V LEC
Sbjct: 2269 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGL-----APGQLV-LECS 2322
Query: 294 VTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSD 353
V P P++ W +G L Q G L ++ A D+G Y+C A N +GS
Sbjct: 2323 VEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTA---DSGDYSCTARNAAGST 2379
Query: 354 TTSAEVFIEGASSTDSD--------SESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTG 405
+ + V I + S +++ +A +P + + SP+
Sbjct: 2380 SVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPR-- 2437
Query: 406 VTTAVIQPLSVPVQQVHSPTS--YLC---------RPDGTTTAYFPPVFTKELQNTAVAE 454
++ S+ +Q V + + YLC R PP N +
Sbjct: 2438 --FEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA 2495
Query: 455 GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPE 514
+L C G+P V W++ G ++ DFR+ Q R L++ P+
Sbjct: 2496 HTPALLPCEASGSPKPLVVWWKDGQKL----DFRLQQGAYRLLPSN----ALLLTAPGPQ 2547
Query: 515 DAGIFTCSARNDYGSATSTAQLVV 538
D+ F C N+ G A Q+ V
Sbjct: 2548 DSAQFECVVSNEVGEAHRLYQVTV 2571
Score = 63.5 bits (153), Expect = 1e-09
Identities = 65/270 (24%), Positives = 96/270 (35%), Gaps = 37/270 (13%)
Query: 288 VYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLAT 347
V L C TG P P V W G +L G L I +A GRYTC A
Sbjct: 2592 VVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALE---IGQALPIHAGRYTCSAR 2648
Query: 348 NPSGSD------TTSAEVFIEGASSTDSD--SESLAFKSRAGAMPQAQKKTTSVSLTIGS 399
N +G T A ++ S E + A +P+ L +
Sbjct: 2649 NSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVA- 2707
Query: 400 SSPKTGVTTAVIQ--PLSVPVQQVHSPTSYLCRPDGTT---------TAYFPPVFTKELQ 448
TGV+T V+ L + +YLC + PPV L
Sbjct: 2708 ----TGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLP 2763
Query: 449 NTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVI 508
+ + EG L C+ RG+P + W + G + + + + T +P L++
Sbjct: 2764 DLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGA--------EGKFTIQPSG--ELLV 2813
Query: 509 AETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+DAG +TC+A N G A L +
Sbjct: 2814 KNLEGQDAGTYTCTAENAVGRARRRVHLTI 2843
Score = 63.2 bits (152), Expect = 1e-09
Identities = 59/198 (29%), Positives = 82/198 (41%), Gaps = 17/198 (8%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P+ P + V E ++C SG+P PD+SW +PV S + V +G L
Sbjct: 604 PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMGVTVSVDG-RVLR 660
Query: 971 IEPVTSRDAGIYTCIATNRAGQNS--FSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
IE DAG Y C+A+N AG + L + V + P + L NT PVR
Sbjct: 661 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNT------PVR 714
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L C G P P + W K+ + S Q G L + A D+G Y+ A +
Sbjct: 715 LTCNATGAPSPTLMWLKDGNPV--SPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 772
Query: 1089 EAGIVSCTARLDVYISRH 1106
G R DV + H
Sbjct: 773 AVG----EDRQDVVLQVH 786
Score = 60.5 bits (145), Expect = 9e-09
Identities = 112/468 (23%), Positives = 168/468 (35%), Gaps = 75/468 (16%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
VAE V L C +G P P + W EG + Q+ GG L IA A +D G
Sbjct: 2678 VAE-EEVLLPCEASGIPRPTITWQKEGLNVATGVSTQV-LPGGQLR---IAHASPEDAGN 2732
Query: 342 YTCLATNPSGSDTTSAEVFIE----------GASSTDSDSESLAFKSRAGAMPQA--QKK 389
Y C+A N +GS + ++ S+T+ L K+R P K
Sbjct: 2733 YLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKD 2792
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQP---LSVPVQQVHSPTSYLCRPDGTT---------TA 437
VS G + IQP L V + +Y C + T
Sbjct: 2793 GQPVSGAEGKFT---------IQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 2843
Query: 438 YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
PVFT + ++ G + L C RG+P ++ W + D P
Sbjct: 2844 LVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGW-----TVNDRP-------VTEGV 2891
Query: 498 AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA---NTENCSY--ESMG 552
+E + TL A ED+G + C A N G + + + V A E SY E +G
Sbjct: 2892 SEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVG 2951
Query: 553 ES-NNDHFQHFPPPPPI--------LETSSLELASKKPS-EIQQVNNPELGLSRAALQMQ 602
S D P P I L S L + S I++ + G + + +
Sbjct: 2952 GSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAENE 3011
Query: 603 FNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKAS 662
A++ V S V + + + +S A+ T EP P + + G P +AS
Sbjct: 3012 MGVAKKVVILVLQSAPV-FQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRAS 3070
Query: 663 RTARIASDEEI---------QGTKDAVIQDLERKLRFKEDLLNNGQPR 701
R R D + GT D V +L + L+ G+P+
Sbjct: 3071 RRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3118
Score = 60.1 bits (144), Expect = 1e-08
Identities = 62/290 (21%), Positives = 103/290 (35%), Gaps = 55/290 (18%)
Query: 280 QEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDT 339
+E+ E + YL C P P + W+ E + L ++ + +GG + + + A ++
Sbjct: 1478 REIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSV-LQGGRVLQIPLVRA--ENA 1534
Query: 340 GRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGS 399
GRY+C A+N G D E+ + D+E L ++ T + S T+
Sbjct: 1535 GRYSCKASNEVGEDWLHYELLVLTPPVILGDTEEL-----------VEEVTVNASSTVSL 1583
Query: 400 SSPKTGVTTAVI---------------------QPLSVPVQQVHSPTSYLCRPD---GTT 435
P G I Q L V +V SY+C + G+
Sbjct: 1584 QCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 1643
Query: 436 TAYF-------PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
F P + +L+ V L C V P +V W++ + +
Sbjct: 1644 EKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVF 1703
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+L TL + D+G++TC A N G QL V
Sbjct: 1704 LLPGTH----------TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSV 1743
Score = 58.9 bits (141), Expect = 3e-08
Identities = 57/268 (21%), Positives = 99/268 (36%), Gaps = 31/268 (11%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDD 338
++ V E + V LEC +G P P V WF + + + + + +G L I +A D
Sbjct: 612 NKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG---RVLRIEQAQLSD 668
Query: 339 TGRYTCLATNPSGSDTTSAEVFIE---GASSTDSDSESLAFKSRAGAMPQAQKKTTSVSL 395
G Y C+A+N +GS + + + S + + A + +
Sbjct: 669 AGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLM 728
Query: 396 TIGSSSPKTGVTTAVIQ------PLSVPVQQVHSPTSYLC---------RPDGTTTAYFP 440
+ +P + T +Q L++ + Y C R D + P
Sbjct: 729 WLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMP 788
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P E N +V + V LEC+ PP + W++ G ++ P + K +
Sbjct: 789 PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDR 848
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYG 528
++ DAG +TC A N G
Sbjct: 849 ADVW----------DAGHYTCEALNQAG 866
Score = 57.4 bits (137), Expect = 7e-08
Identities = 69/304 (22%), Positives = 107/304 (35%), Gaps = 36/304 (11%)
Query: 249 LAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAE--GSRVYLECRVTGNPTPRVRWFC 306
+ V N+ + L PR I L ++V S V L C V +P P V W+
Sbjct: 1633 MCVAENQAGSAEKLFTLRVQVPPR-IAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYK 1691
Query: 307 EGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI----- 361
+ + L ++ + HTL + A D+G YTC A N +G D ++ +
Sbjct: 1692 DSQALSLGEEVFLL---PGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPA 1748
Query: 362 ---EGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVI--QPLSV 416
D+ + K+ A + T G T A+ Q L +
Sbjct: 1749 FRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEI 1808
Query: 417 PVQQVHSPTSYLCRPDG---------TTTAYFPPVF-TKELQNTAVAEGQVVVLECRVRG 466
QV Y C+ T T PP F + + + G +VL C V G
Sbjct: 1809 QEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSG 1868
Query: 467 APPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARND 526
P V W + ++ S ++ + R L ++ P AG +TC A N
Sbjct: 1869 VPAPTVTWLKDRMPVESSAVHGVVSRGGR----------LQLSRLQPAQAGTYTCVAENT 1918
Query: 527 YGSA 530
A
Sbjct: 1919 QAEA 1922
Score = 57.4 bits (137), Expect = 7e-08
Identities = 72/310 (23%), Positives = 110/310 (35%), Gaps = 34/310 (10%)
Query: 249 LAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEG 308
L + N + L P L EGS +L C+ G+P P + W +G
Sbjct: 2734 LCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDG 2793
Query: 309 KELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAE--VFIEGASS 366
+ + G+ L++ D G YTC A N G + + +
Sbjct: 2794 QPVSGAEGKFTIQPSGE---LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFT 2850
Query: 367 TDSDSESLAFKSRAGAMPQAQ-KKTTSVSLTIGSSSPKTGVTT----AVIQPLSVPVQQV 421
T SL R A+ T + T+ GV+ + +Q +V +
Sbjct: 2851 TLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSRE-- 2908
Query: 422 HSPTSYLCRPDGTT--TAYFPPVFTKE---LQNTAVA-----EGQVVVLECRVRGAPPLQ 471
+Y+C + T V KE LQ A + G + L+C VRG P
Sbjct: 2909 -DSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPD 2967
Query: 472 VQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSAT 531
+ W + G ++ S LQ +L I T +DAG + C A N+ G A
Sbjct: 2968 IHWIKDGLPLRGSHLRHQLQNG-----------SLTIRRTERDDAGRYQCLAENEMGVAK 3016
Query: 532 STAQLVVTSA 541
LV+ SA
Sbjct: 3017 KVVILVLQSA 3026
Score = 53.9 bits (128), Expect = 8e-07
Identities = 68/293 (23%), Positives = 104/293 (35%), Gaps = 62/293 (21%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELH-NTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
V+ L C+ G P P V W + L +P +I EG +L I D G
Sbjct: 2402 VSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG----SLRIQPVLAQDAG 2457
Query: 341 RYTCLATNPSGSDTTSAEVFI-------------------------EGASSTD------S 369
Y CLA+N +GSD ++ + E + S
Sbjct: 2458 HYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWK 2517
Query: 370 DSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC 429
D + L F+ + GA + S +L + + P+ + +S V + H
Sbjct: 2518 DGQKLDFRLQQGAY----RLLPSNALLLTAPGPQDSAQFECV--VSNEVGEAHRLYQ--- 2568
Query: 430 RPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEI-QDSPDFR 488
T + PP + + V VVL C G P V W + G+++ +R
Sbjct: 2569 -----VTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYR 2623
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA 541
+ P E I + P AG +TCSARN G A L V ++
Sbjct: 2624 V---SPSGALE--------IGQALPIHAGRYTCSARNSAGVAHKHVFLTVQAS 2665
Score = 51.2 bits (121), Expect = 5e-06
Identities = 70/291 (24%), Positives = 101/291 (34%), Gaps = 52/291 (17%)
Query: 285 GSRVYLECRVTGNPTPRVRWFCEGKELHNTP--------DI--------QIHCEGGDLHT 328
G + LEC G P P + W + +L P D+ ++ EG LH
Sbjct: 33 GQSLTLECDANGFPVPEIVWL-KDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHF 91
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGA------ 382
I E D+G Y+C A N +G+ + + S + AGA
Sbjct: 92 PRIQEG---DSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQC 148
Query: 383 ----MPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---RPDGTT 435
+P Q + T + P V Q L + V Y C P G
Sbjct: 149 WTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDG-QVLRITGSHVGDEGRYQCVAFSPAGQQ 207
Query: 436 TAYF------PPVF--TKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
F PP + E AV E +V L C RG P + WF+ G+ + S
Sbjct: 208 ARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKV 267
Query: 488 RILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+ + R L + DAG++TC A N G+A +L V
Sbjct: 268 -VYTRGGRQ---------LQLGRAQSSDAGVYTCKASNAVGAAEKATRLDV 308
Score = 50.8 bits (120), Expect = 7e-06
Identities = 64/305 (20%), Positives = 104/305 (34%), Gaps = 45/305 (14%)
Query: 254 NRKSHPQPHSALHFPAAPRF-IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELH 312
N+ H + H L+ AP F +++ + V EG L C G P P++ W +G+ L
Sbjct: 863 NQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLP 922
Query: 313 NTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE---------- 362
H L + +A G YTC +N G+ + ++ +
Sbjct: 923 GEGAGLQHVSAVG-RLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 981
Query: 363 --GASSTDSDSESLAFKSRAGAMPQA---QKKTTSVSLTIGSSSPKTGVTTAVIQPLSVP 417
S D + + G P ++ V +G G Q L V
Sbjct: 982 PPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG------QSLHVE 1035
Query: 418 VQQVHSPTSYLCRPDGTT---------TAYFPPVFTKELQ---NTAVAEGQVVVLECRVR 465
Q Y C + + PP +L N A + L C
Sbjct: 1036 RAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAM 1095
Query: 466 GAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARN 525
G PP ++WFR + D +L L + +T +D+G+++C A N
Sbjct: 1096 GIPPPAIRWFRGEEPVSPGEDTYLLAGG----------WMLKMTQTQEQDSGLYSCLASN 1145
Query: 526 DYGSA 530
+ G A
Sbjct: 1146 EAGEA 1150
Score = 48.9 bits (115), Expect = 3e-05
Identities = 63/282 (22%), Positives = 99/282 (35%), Gaps = 45/282 (15%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGK-----ELHNTPDIQIHCEGGDLHTLIIAEAFE 336
V GS V L C G P P V W +G+ L P +Q+ G
Sbjct: 2136 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPSLQLEAVGAG----------- 2184
Query: 337 DDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQA---QKKTTSV 393
D+G Y+C+A + +G ++ + + + GA + + T
Sbjct: 2185 -DSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQP 2243
Query: 394 SLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---RPDGTTTAYF------PPVFT 444
++T +T + V +V Y C P G F PP
Sbjct: 2244 NITWHKDGQ--ALTRLENNSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIV 2301
Query: 445 KELQNTAV---AEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
V A GQ+V LEC V P ++ W R G +Q+ T PE
Sbjct: 2302 GPRGPRFVVGLAPGQLV-LECSVEAEPAPKITWHRDGIVLQEDAH----------TQFPE 2350
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT 543
L + D+G ++C+ARN GS + ++ + + T
Sbjct: 2351 RGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPT 2392
Score = 48.5 bits (114), Expect = 3e-05
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHT 328
+AP F + + V G V L C+ TG PTP + W G+ L + ++ +G +
Sbjct: 3025 SAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG----S 3080
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
L + D G Y C+A N GS T A + + G
Sbjct: 3081 LWLENVETGDAGTYDCVAHNLLGSATARAFLVVRG 3115
Score = 47.0 bits (110), Expect = 1e-04
Identities = 41/140 (29%), Positives = 58/140 (41%), Gaps = 13/140 (9%)
Query: 254 NRKSHPQPHSALHFPAAPRFIQKLRSQEVAE-GSRVYLECRVTGNPTPRVRWFCEGKELH 312
NR Q S +H AP + S V G + L+C V G+P P + W +G L
Sbjct: 2919 NRVGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLR 2978
Query: 313 NTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSD-------TTSAEVF-IEGA 364
+ ++ + G +L I DD GRY CLA N G SA VF +E
Sbjct: 2979 GS-HLRHQLQNG---SLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVEPQ 3034
Query: 365 SSTDSDSESLAFKSRAGAMP 384
T + +A + +A P
Sbjct: 3035 DMTVRSGDDVALRCQATGEP 3054
Score = 46.6 bits (109), Expect = 1e-04
Identities = 69/301 (22%), Positives = 105/301 (34%), Gaps = 48/301 (15%)
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
+H P P + + + V V LEC+ P P + W+ +G+ L P + +
Sbjct: 785 VHMP--PSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHL---SA 839
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGS-------DTTSAEVFIEGASST----DSDSES 373
D L + A D G YTC A N +G + A VF S T +
Sbjct: 840 DKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTR 899
Query: 374 LAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGV----TTAVIQPLSVPVQQVHSPTSYLC 429
L+ + R P+ + G P G +AV + L + Q+ +Y C
Sbjct: 900 LSCECRGVPFPKISWRKD------GQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTC 953
Query: 430 R---------PDGTTTAYFPPVFTKELQ---NTAVAEGQVVVLECRVRGAPPLQVQWFRQ 477
D + PP + +V + V LEC G PP V W R
Sbjct: 954 ECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERD 1013
Query: 478 GSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLV 537
G + + LQ + +S L + G ++C A N G A +L
Sbjct: 1014 GQPVGAELGLQ-LQNQGQS---------LHVERAQAAHTGRYSCVAENLAGRAERKFELS 1063
Query: 538 V 538
V
Sbjct: 1064 V 1064
Score = 35.4 bits (80), Expect = 0.30
Identities = 25/98 (25%), Positives = 41/98 (41%), Gaps = 5/98 (5%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F+++ + + G V C+ G P P I W + G+ + T+ DG+
Sbjct: 3026 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP---DGSLW 3082
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQ 873
L + D G Y +A N G + L+V+ Q
Sbjct: 3083 LENVET--GDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3118
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 123 bits (308), Expect = 1e-27
Identities = 255/1115 (22%), Positives = 396/1115 (35%), Gaps = 168/1115 (15%)
Query: 60 SEKEISQIFSTSPASLCEHPSHK------ETKLGEHASRRPQDNRSTPVQPLAEKQTKSI 113
S E ++F ASL E + E + + R + + E ++
Sbjct: 462 SVAERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATL 521
Query: 114 SSPVSKRKPAMSPLLTRPSYIRSLRKAEKRGAKTPSTNV------KPKTPHQRKG----- 162
S R+P PL +RPS ++ R A+ PS + +P P R
Sbjct: 522 QRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDEPGRPRSRGPAGRTE 581
Query: 163 ---GPQSQLCDK------AANLIEELTSIFK--AAKP---RNRSPNGESSSPDS------ 202
GPQ ++ + + I+E S AA P R ++P G P +
Sbjct: 582 PGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEARTKAPPGRKREPPAQAVRFL 641
Query: 203 --------GYLSP----KNQPSALLSASASQSPMEDQ--GEMEREVKSPGARHCYQDNQD 248
G P KN+ + P ED G +R GAR + +
Sbjct: 642 PWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWDRR----GARSQGKGRRA 697
Query: 249 LAV-PHNRKSHPQPHSALHFPA-APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFC 306
P S SA P AP F L++ VA G+ V L+C +T NP P+V W
Sbjct: 698 RPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHK 757
Query: 307 EGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASS 366
+G L + + + E G+ HTL++ EA D G Y ATN G T +A + + S
Sbjct: 758 DGSALRSEGRLLLRAE-GERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGS 816
Query: 367 TDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTS 426
T S + + P+ P+ G T P P+
Sbjct: 817 TSPFSSPITSDEEYLSPPE--------------EFPEPGETW--------PRTPTMKPSP 854
Query: 427 YLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
R T + PP F L + +V EGQ V++ RV+G P V W R ++ PD
Sbjct: 855 SQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVR--PD 912
Query: 487 FRILQKKPRSTAEPE-EICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTEN 545
R R E E +C L I DAG +TC A N+YG+ A+L V A+ E+
Sbjct: 913 QR------RFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV-RAHPES 965
Query: 546 CSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAAL---QMQ 602
S + + E + E P++++ L + AL +M
Sbjct: 966 RSLAVLAPLQD-------VDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMH 1018
Query: 603 FNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKAS 662
F+ + + +G+ K ++ K T + L+ PL +
Sbjct: 1019 FDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEG 1078
Query: 663 RTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFN 722
R AR D +I GT V+ + G P E R+ G S + +
Sbjct: 1079 RAARF--DCKISGTPPPVV-----------TWTHFGCPMEESENLRLRQDGGLHSLHIAH 1125
Query: 723 IQEPEE----ETANQEYKVSSCEQRLISE--------IEYRLERSPVDESGDEVQYGDVP 770
+ +E +A + + C +L E +LE+ P +E + G+
Sbjct: 1126 VGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMP--SIPEEPEQGE-- 1181
Query: 771 VENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ-RD 829
+E P F L+ ++ C+V G P P I WF +G +I D Q RD
Sbjct: 1182 LERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRD 1241
Query: 830 LDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRR 889
+ L A G Y + AN G+ +C L V V P P G P V
Sbjct: 1242 VH---RLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDV-----VPGPPDGAPQVVA 1293
Query: 890 PRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKL--CRMDCKVSGLPTPDLSWQLD 947
R + P L TVQ L + V+GL P W
Sbjct: 1294 VTGRMVTLTWNPPRSLDMAIDPDSL----TYTVQHQVLGSDQWTALVTGLREP--GWAAT 1347
Query: 948 GKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAH 1007
G +R H V V S +++ S ++L+
Sbjct: 1348 G--LRKGVQHIFRVLSTTVKS------------------SSKPSPPSEPVQLLEHGPTLE 1387
Query: 1008 KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRV-SMHQDNHGY 1066
+ P ++K V +G P + V Q+ W+ +L + V + Q +
Sbjct: 1388 EAPAMLDKPDIVYVVEGQPASVTVTFNHV-EAQVVWRSCRGALLEARAGVYELSQPDDDQ 1446
Query: 1067 ICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
CL I ++ D G T +A+N G +C+ L++
Sbjct: 1447 YCLRICRVSRRDMGALTCTARNRHGTQTCSVTLEL 1481
Score = 115 bits (288), Expect = 2e-25
Identities = 144/604 (23%), Positives = 230/604 (38%), Gaps = 93/604 (15%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP F + L EV EG +C+++G P P V W G + + ++++ +GG LH+L
Sbjct: 1063 APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGG-LHSL 1121
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKK 389
IA +D G Y A N G SA++++E + S S K MP
Sbjct: 1122 HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEK-----MP----- 1171
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQN 449
S+P + L PD F + LQ+
Sbjct: 1172 -------------------------SIPEEPEQGELERLSIPD----------FLRPLQD 1196
Query: 450 TAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIA 509
V + +LEC+V G P + WF G IQ S D R+ Q + ++ LV
Sbjct: 1197 LEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYR--------DVHRLVFP 1248
Query: 510 ETFPEDAGIFTCSARNDYGSATSTAQLVVTSA--NTENCSYESMGESNNDHFQHFPPPPP 567
P+ AG++ N G A A L VT + + + + + + PP
Sbjct: 1249 AVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPP-- 1306
Query: 568 ILETSSLELASKKPSEIQQVNNPELGLSR-AALQMQFNAAERETNGVHPSRGVNGLINGK 626
SL++A S V + LG + AL G+ +GV +
Sbjct: 1307 ----RSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPGWAATGLR--KGVQHIFRVL 1360
Query: 627 ANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTKDAVIQDLER 686
+ + KS P SP EP LL P A + K ++ +E
Sbjct: 1361 STTVKSSSKP----SPPSEPVQLLEHG----PTLEEAPAML--------DKPDIVYVVEG 1404
Query: 687 KLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLIS 746
+ N+ + ++ + R R L A V+ + +P+++ +Y + C R+
Sbjct: 1405 QPASVTVTFNHVEAQVVW--RSCRGALLEARAGVYELSQPDDD----QYCLRIC--RVSR 1456
Query: 747 EIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKP 806
L + + G Q V +E AP FE ++ ++ G F V G P P
Sbjct: 1457 RDMGALTCTARNRHG--TQTCSVTLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLP 1514
Query: 807 KIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRL 866
I W+KD + + +S H + + + CSL ++ D G YT A N G +SC L
Sbjct: 1515 DIMWYKD-EVLLTESSHVSFVYE-ENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAEL 1572
Query: 867 MVQA 870
V +
Sbjct: 1573 AVHS 1576
Score = 112 bits (280), Expect = 2e-24
Identities = 185/782 (23%), Positives = 288/782 (36%), Gaps = 123/782 (15%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEG--GDL 326
A P F L Q V EG V + RV G P P V W + + PD + E G L
Sbjct: 867 APPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVR--PDQRRFAEEAEGGL 924
Query: 327 HTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQ- 385
L I A D G YTC A N G+ A + + +S SLA + +
Sbjct: 925 CRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRA----HPESRSLAVLAPLQDVDVG 980
Query: 386 AQKKTTSVSLTIGSSSPKTG--VTTAVIQPLSVPVQQ-------------VHSPTS--YL 428
A + L G + + ++QP + + VH S Y
Sbjct: 981 AGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYT 1040
Query: 429 CRPDG-----------TTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQ 477
C+ T P+FT+ L++ V EG+ +C++ G PP V W
Sbjct: 1041 CKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHF 1100
Query: 478 GSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLV 537
G +++S + R+ Q + +L IA ED G++ SA N +G A +AQL
Sbjct: 1101 GCPMEESENLRLRQDGG--------LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLY 1152
Query: 538 VTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRA 597
V T + G S+ + P P E LE S P ++ + + E+GL++
Sbjct: 1153 VEEPRTA-----ASGPSSK--LEKMPSIPEEPEQGELERLSI-PDFLRPLQDLEVGLAKE 1204
Query: 598 A-LQMQFNAAERET-NGVHPSRGVNGLINGKANSNKS---LPTPAVLLSPTKEPPPLLAK 652
A L+ Q T + H + + + + L PAV ++A
Sbjct: 1205 AMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIAN 1264
Query: 653 PKLGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPR----------L 702
KLG KA+ A + + + G D Q + R L PR L
Sbjct: 1265 -KLG---KAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVT--LTWNPPRSLDMAIDPDSL 1318
Query: 703 TYEERMARRLLGAD--SATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDES 760
TY + ++LG+D +A V ++EP V + L + ++ + SP E
Sbjct: 1319 TYT--VQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEP 1376
Query: 761 GDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFK-DGKQISP 819
+++G E AP K + EG P + T + + ++ W G +
Sbjct: 1377 VQLLEHGPTLEE---APAMLDKPDIVYVVEGQPASVTVTF-NHVEAQVVWRSCRGALLEA 1432
Query: 820 KSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPR 879
++ Y + + D L + D G T A N G +C+ L +
Sbjct: 1433 RAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-------- 1484
Query: 880 SPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPT 939
P F D+ V G+ R V G P
Sbjct: 1485 -------------------------------PRFESIMEDVEVGAGETARFAVVVEGKPL 1513
Query: 940 PDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL 999
PD+ W D + + +S+H V E SL++ ++D G+YTC A N AG+ S EL
Sbjct: 1514 PDIMWYKD-EVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAEL 1572
Query: 1000 VV 1001
V
Sbjct: 1573 AV 1574
Score = 68.6 bits (166), Expect = 3e-11
Identities = 46/129 (35%), Positives = 66/129 (51%), Gaps = 7/129 (5%)
Query: 974 VTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRV 1033
V+ RD G TC A NR G + S+ L +A + P F +++ V G R V
Sbjct: 1454 VSRRDMGALTCTARNRHGTQTCSVTLELA-----EAPRFESIMEDVEVGAGETARFAVVV 1508
Query: 1034 LGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIV 1093
G P P I W K+ LT S+ ++++N + +L GA +D G YT +A+N AG V
Sbjct: 1509 EGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGA--QDGGVYTCTAQNLAGEV 1566
Query: 1094 SCTARLDVY 1102
SC A L V+
Sbjct: 1567 SCKAELAVH 1575
Score = 54.7 bits (130), Expect = 5e-07
Identities = 80/343 (23%), Positives = 127/343 (37%), Gaps = 37/343 (10%)
Query: 43 LDLARRAIADSETED---FDSEKEISQIFSTSPASLCEHPSHKETKLGEHASRRPQDNRS 99
L L R ++ S +E+ F +E I+ SPA + E SR QD R+
Sbjct: 2345 LSLGLRLLSRSRSEERGPFRGAEEEDGIYRPSPAG-----TPLELVRRPERSRSVQDLRA 2399
Query: 100 TPVQPLAEKQTKSIS-----SPVSKRKPAMSPL-----------LTRPSYIRSLRKAEKR 143
L + + S+S +P ++R PA R S + ++R+
Sbjct: 2400 VGEPGLVRRLSLSLSQRLRRTPPAQRHPAWEARGGDGESSEGGSSARGSPVLAMRRRLSF 2459
Query: 144 GAKTPSTNVKPKTPHQRKGGPQSQ---LCDKAANLIEELTSIFKAAKPRNR-SPNGESSS 199
+ S+ ++ + GG + L + E S+ + P N+ + +++
Sbjct: 2460 TLERLSSRLQRSGSSEDSGGASGRSTPLFGRLRRATSEGESLRRLGLPHNQLAAQAGATT 2519
Query: 200 PDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHP 259
P + L S + S S +P E + + P A H
Sbjct: 2520 PSAESLG-----SEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLSASVQEELGHQ 2574
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
S FP P F KL+ Q + EG L C P P + W + K L + P + I
Sbjct: 2575 YVRSESDFP--PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVII 2632
Query: 320 -HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFI 361
C+ G L I A + G Y C ATN GS T+S V +
Sbjct: 2633 VSCKDGR-QLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
Score = 52.4 bits (124), Expect = 2e-06
Identities = 32/92 (34%), Positives = 43/92 (46%), Gaps = 9/92 (9%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
PVF+ L+N V G VRL V G P P + W ++ + L S CL
Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPS---------CL 93
Query: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
++ +DAG Y+ A+NE G SC A L V
Sbjct: 94 WLRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125
Score = 50.8 bits (120), Expect = 7e-06
Identities = 33/113 (29%), Positives = 49/113 (43%), Gaps = 15/113 (13%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
PVF + L+N AV G V L V G P ++WFR G Q P EP
Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDG------------QLLPAPAPEP 90
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGE 553
L + +DAG+++C A+N+ G A+ A L V + + + +
Sbjct: 91 S---CLWLRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAEDDISD 140
Score = 50.1 bits (118), Expect = 1e-05
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P F +++ V G+ V G P + W++ + +S + +
Sbjct: 1485 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYE-------- 1536
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDH 558
E C+LV+ T +D G++TC+A+N G + A+L V SA T E +GE + DH
Sbjct: 1537 ENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTA-MEVEGVGE-DEDH 1592
Score = 48.1 bits (113), Expect = 4e-05
Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 767 GDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTI 826
G PV AP F LK+ + G V V+G P+P + WF+DG+ + +
Sbjct: 33 GGAPVAVAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAP---- 88
Query: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAV 871
+ +C L D G Y+ MA N +GR SC L V V
Sbjct: 89 ----EPSC-LWLRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEV 128
Score = 47.8 bits (112), Expect = 6e-05
Identities = 45/175 (25%), Positives = 69/175 (39%), Gaps = 27/175 (15%)
Query: 378 SRAGAM-PQAQKKTTSVSLTIGSSSP---KTGVTTAVIQP----------LSVPVQQVHS 423
++AGA P A+ + S T GSS+P ++ + +P LS VQ+
Sbjct: 2513 AQAGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLSASVQEELG 2572
Query: 424 PTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQD 483
D FPPVF +L++ + EG+ L C P + W + ++
Sbjct: 2573 HQYVRSESD------FPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRS 2626
Query: 484 SPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P I+ K L I AG++ CSA N GS TS+ + V
Sbjct: 2627 EPSVIIVSCKDGRQ-------LLSIPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
Score = 47.8 bits (112), Expect = 6e-05
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Query: 906 ERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENG 965
E F P F D + EG+ + C + P P +SW D K +R + + ++ ++G
Sbjct: 2579 ESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDG 2638
Query: 966 VHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAH-KPPVFIEKLQNTGV 1021
L I R AG+Y C ATN G + S + VA PP + Q+T +
Sbjct: 2639 RQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVPQTYQDTAL 2695
Score = 46.2 bits (108), Expect = 2e-04
Identities = 35/106 (33%), Positives = 48/106 (45%), Gaps = 10/106 (9%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP F++ L++ V GS V L V+G P P +RWF +G +L P + C L
Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDG-QLLPAPAPEPSC-------L 93
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSA--EVFIEGASSTDSDSES 373
+ D G Y+C+A N G + A V G S T D S
Sbjct: 94 WLRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAEDDIS 139
Score = 45.1 bits (105), Expect = 4e-04
Identities = 34/94 (36%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Query: 1005 EAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNH 1064
E+ PPVF KL++ + +G L C P P I W K+ +SL S V +
Sbjct: 2579 ESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSL-RSEPSVIIVSCKD 2637
Query: 1065 GYICLLIQGATKEDAGWYTVSAKNEAGIV--SCT 1096
G L I A K AG Y SA N G + SCT
Sbjct: 2638 GRQLLSIPRAGKRHAGLYECSATNVLGSITSSCT 2671
Score = 43.9 bits (102), Expect = 8e-04
Identities = 27/102 (26%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 265 LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGG 324
L APRF + EV G V G P P + W+ + L + + E
Sbjct: 1479 LELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEEN 1538
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASS 366
+ +L++ D G YTC A N +G + AE+ + A +
Sbjct: 1539 EC-SLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQT 1579
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/120 (28%), Positives = 47/120 (39%), Gaps = 1/120 (0%)
Query: 762 DEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKS 821
+E+ + V E+ P F +KLK + EG T C A P P I W KD K + +
Sbjct: 2569 EELGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEP 2628
Query: 822 DHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSP 881
I DG L + G Y A N G I+ + + V V + P P
Sbjct: 2629 S-VIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVP 2687
Score = 40.0 bits (92), Expect = 0.012
Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGK--PVRPDSAHKMLVRENGVHS 968
P FL+ + V G R+ VSG P P L W DG+ P + +R G
Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSCLWLRRCG--- 99
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
++DAG+Y+C+A N G+ S L V
Sbjct: 100 -------AQDAGVYSCMAQNERGRASCEAVLTV 125
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 122 bits (307), Expect = 1e-27
Identities = 101/350 (28%), Positives = 146/350 (41%), Gaps = 32/350 (9%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F +L++ ++ +G PV+F C V G P P + WFKDGK + + DHY I D G
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLE-EDDHYMINEDQQGGHQ 5183
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVN---QRGRSPRSPSGHPHVRRPRS 892
L TA D G Y +A N G S L V + S + + S
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEG-KLCRMDCKVSGLPTPDLSWQLDGKPV 951
G E+ + + P ++ DL V G +L + KV G P P L W DG+P+
Sbjct: 5244 SREQEGTESTTDEGQL--PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPL 5301
Query: 952 RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV---------A 1002
SAH + + +H+L I VT D+G Y +N G S L+V
Sbjct: 5302 TA-SAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKP 5360
Query: 1003 AKEAHK---PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSM 1059
A + H+ PP +E+ V G + +V G P P + W +E + +
Sbjct: 5361 ASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA----ERGVLWI 5416
Query: 1060 HQDNHGYI--------CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
D GY L++ ++ G YT A N AG C+A L V
Sbjct: 5417 GPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466
Score = 108 bits (269), Expect = 4e-23
Identities = 59/191 (30%), Positives = 97/191 (50%), Gaps = 5/191 (2%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F + D T + G+ ++ C+V+G P P +SW DGK V+ D H ++ +G +LI
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 1030
++ +T D+G Y C A + AG S +++V PP F+ K++ + +G +
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV-----PPRFVNKVRASPFVEGEDAQFT 6128
Query: 1031 CRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1090
C + G P PQI W K+ LT ++ + G + L+I+ A+KED G Y N
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188
Query: 1091 GIVSCTARLDV 1101
G +A L +
Sbjct: 6189 GSARASAELRI 6199
Score = 105 bits (262), Expect = 2e-22
Identities = 82/280 (29%), Positives = 124/280 (44%), Gaps = 21/280 (7%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F ++ ++ EG TF CRV G+P+P + W KDG+++ +L +
Sbjct: 109 APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMV--QAVNQRGRSPRSPSG-HPHVRRPRS 892
L A+ D G Y + A NP G S L+V A + R S + H++R R
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRRE 228
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
R G P TV EGK R+ C V+G P P+ W+ DG+ V
Sbjct: 229 AMRAEGAPASPPS---------TGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVT 279
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSR--DAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP 1010
H +V E+ + +++ + + D G+YTC A+N GQ S+ +VV +E P
Sbjct: 280 EGRRH--VVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVV--REPAVP- 334
Query: 1011 VFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESL 1050
F ++LQ+ V + C V P + W KE L
Sbjct: 335 -FKKRLQDLEVREKESATFLCEV-PQPSTEAAWFKEETRL 372
Score = 98.6 bits (244), Expect = 3e-20
Identities = 95/353 (26%), Positives = 134/353 (37%), Gaps = 65/353 (18%)
Query: 768 DVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ 827
D P +G AP F + K + + G T +C++ GNP P++ W KD + ++ + + +
Sbjct: 2 DQPQFSG-APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGA-RFRLA 59
Query: 828 RDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHV 887
+D D L L D G Y A N G L V A
Sbjct: 60 QDGD-LYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQA--------- 109
Query: 888 RRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLD 947
PHFL P + V+EG C+V G P P +SW D
Sbjct: 110 -----------------------PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKD 146
Query: 948 GKPVRPDSAHKMLVRENGVHSLI-IEPVTSRDAGIYTCIATNRAGQNSFSLELVV---AA 1003
G+ + ++ V E G S + I RD G Y A N G S + LVV AA
Sbjct: 147 GRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAA 206
Query: 1004 KEAHKP----PVFIEKLQ----------------NTG-----VADGYPVRLECRVLGVPP 1038
A +P + LQ +TG V +G RL C V G P
Sbjct: 207 DTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPK 266
Query: 1039 PQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
P+ WKK+ + +T V +++D L I + D G YT +A N G
Sbjct: 267 PETVWKKDGQLVTEGRRHV-VYEDAQENFVLKILFCKQSDRGLYTCTASNLVG 318
Score = 98.6 bits (244), Expect = 3e-20
Identities = 83/287 (28%), Positives = 126/287 (43%), Gaps = 56/287 (19%)
Query: 259 PQP-HSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDI 317
P+P S L AAP F+ +L++QEV +G V +C VTG P P VRWF +GK L
Sbjct: 5113 PEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHY 5172
Query: 318 QIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSD-----SE 372
I+ + H LII D G Y CLA N G +T AE+ ++ +STD D +E
Sbjct: 5173 MINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-LTSTDYDTAADATE 5231
Query: 373 SLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPD 432
S ++ S G + +++ T +
Sbjct: 5232 SSSYFSAQGYLSSREQEGT----------------------------------------E 5251
Query: 433 GTTTAYFPPVFTKELQNTAVAEG-QVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQ 491
TT P +EL++ VA G ++ + +V+G P ++ WF+ G + S R+
Sbjct: 5252 STTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTD 5311
Query: 492 KKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
KK + TL I ED+G + N G+A S+A+L+V
Sbjct: 5312 KK--------ILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350
Score = 86.3 bits (212), Expect = 1e-16
Identities = 59/193 (30%), Positives = 86/193 (44%), Gaps = 3/193 (1%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P FL P V GK + C++ G PTP +SW+ D +PV A L ++ ++ L
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAA-GARFRLAQDGDLYRLT 68
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE--AHKPPVFIEKLQNTGVADGYPVR 1028
I + D+G Y C A N G+ ++ L V A+ A + P F+ + + V +G
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEAT 128
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
CRV G P P + W K+ L ++ L I+ A D G Y V A+N
Sbjct: 129 FRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAEN 188
Query: 1089 EAGIVSCTARLDV 1101
G S A L V
Sbjct: 189 PLGAASAAAALVV 201
Score = 86.3 bits (212), Expect = 1e-16
Identities = 62/224 (27%), Positives = 86/224 (38%), Gaps = 41/224 (18%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P FE +L G V CRV G PKP I W+KDGK + H I+ D DG+C+L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIE-DPDGSCAL 6072
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
+ T D G Y AA+ G S G+++VQ
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV-------------------------- 6106
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956
P F+ EG+ + C + G P P + W DG + +
Sbjct: 6107 -------------PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNK 6153
Query: 957 HKMLVR-ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL 999
+ L +G+ L+I + D G+Y C NR G S EL
Sbjct: 6154 FQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAEL 6197
Score = 76.6 bits (187), Expect = 1e-13
Identities = 80/329 (24%), Positives = 123/329 (37%), Gaps = 42/329 (12%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G + C VA + W KDG +++ H+ Q DGTCSL T D G YT
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG-DGTCSLLITGLDRADAGCYT 4970
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
+N G+++ + ++V S RR R R FR
Sbjct: 4971 CQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARR-----------LHRLFR 5019
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL- 969
++P +++ +E L + P WQ + H + +R +
Sbjct: 5020 ---TKSPAEVSDEELFLSADEGPAE--PEEPADWQ-----TYREDEHFICIRFEALTEAR 5069
Query: 970 -IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP----------------PVF 1012
+ A + + Q +E+ + +KE P PVF
Sbjct: 5070 QAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCI-SKETPAPVVPPEPLPSLLTSDAAPVF 5128
Query: 1013 IEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQ 1072
+ +LQN V DGYPV +C V G P P + W K+ + L D +++D G L+I
Sbjct: 5129 LTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGK-LLEEDDHYMINEDQQGGHQLIIT 5187
Query: 1073 GATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
D G Y A+N G+ S A L V
Sbjct: 5188 AVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 76.6 bits (187), Expect = 1e-13
Identities = 60/249 (24%), Positives = 100/249 (40%), Gaps = 30/249 (12%)
Query: 760 SGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVT-FTCRVAGNPKPKIYWFKDGKQIS 818
S E + + + G P +L+ ++ G + F +V G P P++YWFKDG+ ++
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLT 5302
Query: 819 PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
+ + + T L + T +D G Y +N G + RL+V+ ++ P
Sbjct: 5303 ASAHIRMTDKKILHT--LEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKP 5360
Query: 879 RSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP 938
S + E+ P L+ V++G KV G P
Sbjct: 5361 ASD----------------------VHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRP 5398
Query: 939 TPDLSWQLDGKP-----VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN 993
P + W + + PD+ + HSL++ V + G YTCIA+N AGQ
Sbjct: 5399 VPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQA 5458
Query: 994 SFSLELVVA 1002
S L V+
Sbjct: 5459 LCSASLHVS 5467
Score = 67.8 bits (164), Expect = 5e-11
Identities = 65/271 (23%), Positives = 101/271 (37%), Gaps = 53/271 (19%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEG-GDLHT 328
AP F+ + S V EGS CRV G+P P V W +G+ L ++ E G+
Sbjct: 109 APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQK 388
L I A D G Y A NP G+ + +A + ++ S +D+ S S A + Q+
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVD---SDAADTASRPGTSTAALLAHLQR 225
Query: 389 KTTSVSLT-IGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKEL 447
+ ++ +S P TG T
Sbjct: 226 RREAMRAEGAPASPPSTGTRTC-------------------------------------- 247
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
V EG+ L C V G P + W + G + + + + + +E L
Sbjct: 248 ---TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYE-------DAQENFVLK 297
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
I D G++TC+A N G S+ +VV
Sbjct: 298 ILFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 67.4 bits (163), Expect = 7e-11
Identities = 74/280 (26%), Positives = 117/280 (41%), Gaps = 34/280 (12%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
++ LR + E R LEC+V+ + +VRWF +EL P ++ +G LII++
Sbjct: 2293 VRPLRDKIAMEKHRGVLECQVS-RASAQVRWFKGSQELQPGPKYELVSDGL-YRKLIISD 2350
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDS-ESLAFKSRAGAMPQAQKKTTS 392
+D YTC A G TSA+ F+E S T + + A A + + S
Sbjct: 2351 VHAEDEDTYTCDA----GDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPS 2406
Query: 393 V---SLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAY----------- 438
V +G + + G + Q +V + S + P T
Sbjct: 2407 VRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSD 2466
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
P V T+ L+ E Q VVL C R AP VQW++ + + S F++ +
Sbjct: 2467 IPVVLTRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEG----- 2520
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ L I P DAG++ C A GSA S+ ++ V
Sbjct: 2521 ---QMAELRILRLMPADAGVYRCQA----GSAHSSTEVTV 2553
Score = 65.5 bits (158), Expect = 3e-10
Identities = 73/311 (23%), Positives = 116/311 (37%), Gaps = 62/311 (19%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
F +L + ++ E FTC+ +P + W K ++ H Q L +L
Sbjct: 2918 FTEELTNLQVEEKGTAVFTCKTE-HPAATVTWRKGLLELRASGKHQPSQEGL----TLRL 2972
Query: 839 TASTLD--DDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
T S L+ D YT Q R +L+VQ GR
Sbjct: 2973 TISALEKADSDTYTCDIGQAQSR----AQLLVQ-----GR-------------------- 3003
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956
R H ++ D+ VQEG C++S + W LD P+ +
Sbjct: 3004 -------------RVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANEL 3050
Query: 957 HKMLVRENGVHSLIIEPVTSRDAG-IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK 1015
+++ + G H L + + +D+G IY RA A + KP VF +
Sbjct: 3051 NEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRAS---------AALRVTEKPSVFSRE 3101
Query: 1016 LQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGAT 1075
L + + +G + L C P + W K+ ++L S H+ + LLI GAT
Sbjct: 3102 LTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQ--LLITGAT 3158
Query: 1076 KEDAGWYTVSA 1086
+D+G Y A
Sbjct: 3159 LQDSGRYKCEA 3169
Score = 65.5 bits (158), Expect = 3e-10
Identities = 82/322 (25%), Positives = 121/322 (37%), Gaps = 63/322 (19%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG-TCSLH 837
F +L I EG +T C + P + W KDGK + + Q +G L
Sbjct: 3098 FSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSA---RCQLSHEGHRAQLL 3153
Query: 838 TTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDS 897
T +TL D G Y A +C+ ++ H R R
Sbjct: 3154 ITGATLQDSGRYKCEAGG-----ACSSSIV----------------RVHARPVR------ 3186
Query: 898 GDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAH 957
F +A DL V EG + C +S + P + W +RP +
Sbjct: 3187 ---------------FQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKY 3230
Query: 958 KMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQ 1017
L +E + L++ + +D+G Y+C G + S L V A P FI KL+
Sbjct: 3231 S-LRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTAL----PAQFIGKLR 3281
Query: 1018 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC-LLIQGATK 1076
N +G L C + P + W+K +E+L DR + QD G +C L I+G
Sbjct: 3282 NKEATEGATATLRCELSKAAP--VEWRKGSETL-RDGDRYCLRQD--GAMCELQIRGLAM 3336
Query: 1077 EDAGWYTVSAKNEAGIVSCTAR 1098
DA Y+ E S T R
Sbjct: 3337 VDAAEYSCVCGEERTSASLTIR 3358
Score = 63.2 bits (152), Expect = 1e-09
Identities = 76/352 (21%), Positives = 125/352 (35%), Gaps = 81/352 (23%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F E G + LEC V R RW +G EL + I G +L+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 331 IAEAFEDDTGRYT--------------CLATNPSGSDTTSA------------------- 357
I D G YT C+ + S S+ S+
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARRLHRL 5017
Query: 358 ------------EVFI---EGASSTDSDSESLAFKS-------RAGAMPQAQKKTT---- 391
E+F+ EG + + ++ ++ R A+ +A++ T
Sbjct: 5018 FRTKSPAEVSDEELFLSADEGPAEPEEPADWQTYREDEHFICIRFEALTEARQAVTRFQE 5077
Query: 392 -------SVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFT 444
V + + P+ V + + PV S L T+ PVF
Sbjct: 5078 MFATLGIGVEIKLVEQGPRR-VEMCISKETPAPVVPPEPLPSLL-------TSDAAPVFL 5129
Query: 445 KELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
ELQN V +G V +C V G P V+WF+ G +++ + I + +
Sbjct: 5130 TELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH------- 5182
Query: 505 TLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNN 556
L+I P D G++ C A N G +++ A+L V +T+ + ES++
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSS 5234
Score = 62.8 bits (151), Expect = 2e-09
Identities = 60/276 (21%), Positives = 102/276 (36%), Gaps = 75/276 (27%)
Query: 271 PRFIQKLRSQEVAEGSRVY-LECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
P+ +++LR +VA G+R+ + +V G P PR+ WF +G+ L + I++ + LHTL
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRM-TDKKILHTL 5318
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKK 389
I +D+G+Y +N G+ +SA + + G
Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD------------------------ 5354
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQN 449
+P P VH PP +
Sbjct: 5355 ----------------------EPEEKPASDVHE-------------QLVPPRMLERFTP 5379
Query: 450 TAVAEGQVVVLECRVRGAPPLQVQWFRQGSEI------QDSPDFRILQKKPRSTAEPEEI 503
V +G + +V G P V W R+ +E D+P + + A +
Sbjct: 5380 KKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV--------ASSAQQ 5431
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT 539
+LV+ + + G +TC A N G A +A L V+
Sbjct: 5432 HSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVS 5467
Score = 62.0 bits (149), Expect = 3e-09
Identities = 167/845 (19%), Positives = 288/845 (34%), Gaps = 155/845 (18%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
RFI+ +++QE EG+ L+C + N V W + L + + +G I
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIR 3596
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGA--SSTDSDSESLAFKSRAGAMPQAQKK 389
A D TG Y+C+ G + TSA + + T+ A + + K
Sbjct: 3597 GLAMAD-TGEYSCVC----GQERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSK 3651
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQP-----LSVPVQQVHSPTSYLCRPDGTTTAYF----- 439
V G + + G ++ Q L + YLC T+
Sbjct: 3652 MAPVEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRA 3711
Query: 440 -PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
P F + L+N EG L C + A P V+W + ++D + Q R
Sbjct: 3712 MPSKFIEGLRNEEATEGDTATLWCELSKAAP--VEWRKGHETLRDGDRHSLRQDGSR--- 3766
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDH 558
C L I DAG ++C + SAT T + + + E+ + E
Sbjct: 3767 -----CELQIRGLAVVDAGEYSCVCGQERTSATLTVR-ALPARFIEDVKNQEAREGATAV 3820
Query: 559 FQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPS-R 617
Q EL+ P E ++ + G R +L+ E + +G+ +
Sbjct: 3821 LQ-------------CELSKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADT 3867
Query: 618 GVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTK 677
G + G+ ++ +L A P P+ +P + TA + E+
Sbjct: 3868 GEYSCVCGQERTSATLTVRA--------PQPVFREPLQSLQAEEGSTATLQC--ELSEPT 3917
Query: 678 DAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKV 737
V+ + G +L R RL G + V +Q+ + E EY
Sbjct: 3918 ATVVW-------------SKGGLQLQANGRREPRLQGCTAELV--LQDLQREDTG-EYTC 3961
Query: 738 SSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFT 797
+ Q + + + +PV F +L+H ++ EG
Sbjct: 3962 TCGSQATSATLT--VTAAPVR--------------------FLRELQHQEVDEGGTAHLC 3999
Query: 798 CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS-LHTTASTLDDDGNYTIMAANP 856
C ++ + W K Q+ P + + +Q DG + L +D G+YT +
Sbjct: 4000 CELS-RAGASVEWRKGSLQLFPCAKYQMVQ---DGAAAELLVRGVEQEDAGDYTCDTGHT 4055
Query: 857 QGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA 916
Q S + R V RP+ ++R E E
Sbjct: 4056 QSMASLSVR---------------------VPRPKFKTRLQSLEQET------------- 4081
Query: 917 PGDLTVQEGKLCRMDCKVSGLPTPDL-SWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
G + R+ C++S + + W +G + ++M + L+I +
Sbjct: 4082 --------GDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMR-SQGATRELLIHQLE 4132
Query: 976 SRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK-LQNTGVADGYPVRLECRVL 1034
++D G Y C+ GQ + A+ +P V I + L + V V C V
Sbjct: 4133 AKDTGEYACVT---GGQKT------AASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVS 4183
Query: 1035 GVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI-CLLIQGATKEDAGWYTVSAKNEAGIV 1093
+ W + L ++ V+ G I L ++G T EDAG + N A
Sbjct: 4184 RAGATGVQWCL--QGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSA 4241
Query: 1094 SCTAR 1098
T R
Sbjct: 4242 QLTVR 4246
Score = 61.2 bits (147), Expect = 5e-09
Identities = 72/293 (24%), Positives = 115/293 (39%), Gaps = 39/293 (13%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRV-RWFCEGKELHNTPDIQIHCEGGDLHTL 329
P+F +L+S E G L C+++ + V +W EG ELH P ++ +G L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGAT-REL 4126
Query: 330 IIAEAFEDDTGRYTCLATNPSGS--------DTTSAEVFIEGASSTDSDSESLAFKSRAG 381
+I + DTG Y C+ + + T ++ + D D E SRAG
Sbjct: 4127 LIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAG 4186
Query: 382 A---------MPQAQKKTTSVSLTIGS--SSPKTGVTTAVIQPLSVPVQQVHSPTSYLCR 430
A +P + T V++ G + GVT +S + S R
Sbjct: 4187 ATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVR 4246
Query: 431 PDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
T + LQ+ ++EGQ +CR+ A + +W G +Q + I
Sbjct: 4247 APEVT-------ILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDI- 4298
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT 543
T E + L + + EDAG + G+ +S AQL VT+ NT
Sbjct: 4299 ------TVEQGTLHLLTLHKVTLEDAGTVSFHV----GTCSSEAQLKVTAKNT 4341
Score = 59.7 bits (143), Expect = 1e-08
Identities = 174/857 (20%), Positives = 305/857 (35%), Gaps = 155/857 (18%)
Query: 275 QKLRSQEVAE-GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
Q + ++ AE G+ L C V P V W+ +GK+L ++ +++ + G L++ +
Sbjct: 1170 QSVHNEVQAEAGTTAMLSCEVA-QPQTEVTWYKDGKKLSSSSKVRMEVK-GCTRRLVVQQ 1227
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL--AFKSRAGA-------MP 384
+ D G Y+C A G S ++ I + + + + ++ AGA +
Sbjct: 1228 VGKADAGEYSCEA----GGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVA 1283
Query: 385 QAQKKTT--SVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF--- 439
QAQ + T + SSS ++ L V Y C G ++
Sbjct: 1284 QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEAGGQRLSFHLDV 1343
Query: 440 ---PPVFTKEL---QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKK 493
VF KE + G + L C V A +V W++ G ++ S R+
Sbjct: 1344 SEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQA-QTEVTWYKDGKKLSSSSKVRM---- 1398
Query: 494 PRSTAEPEEI-CT--LVIAETFPEDAGIFTCSARNDYGS-ATSTAQLVVTSANTENCSYE 549
E + CT LV+ + D G ++C A S + A+ V A + E
Sbjct: 1399 -------EAVGCTRRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHRE 1451
Query: 550 SMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERE 609
++ T S E+A + + + +L S + ++M+ R
Sbjct: 1452 VQAQAGAS------------TTLSCEVAQAQTEVMWYKDGKKLSFS-SKVRMEAVGCTRR 1498
Query: 610 TNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIAS 669
+ V G + +A S + LS +A+PK F K+ + + +
Sbjct: 1499 LVVQQAGQAVAGEYSCEAGSQR--------LSFHLH----VAEPKAVFAKEQPASREVQA 1546
Query: 670 DEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEE 729
+ T + + ++ + +D +L+ ++ +G V +QE +
Sbjct: 1547 EAGTSATLSCEVAQAQTEVTWYKD-----GKKLSSSSKVRMEAVGCTRRLV--VQEAGQA 1599
Query: 730 TANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIF 789
A EY + +QRL + V + ++ + +V E G +
Sbjct: 1600 DAG-EYSCKAGDQRL--SFHLHVAEPKVVFAKEQPAHREVQAEAGAS------------- 1643
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
T +C VA + ++ W+KDGK++S S + A
Sbjct: 1644 ----ATLSCEVA-QAQTEVTWYKDGKKLSSSS-------------KVRVEA--------- 1676
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEP-IQERF 908
+ CT RL+VQ Q S R R E EP I ER
Sbjct: 1677 ----------VGCTRRLVVQQAGQADAGEYSCEAGGQ----RLSFRLHVAELEPQISERP 1722
Query: 909 FRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS 968
R L V+E + + ++ ++W DG +R H+ + H+
Sbjct: 1723 CRRE------PLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHE-TASQGDTHT 1775
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
L + D+ IY+C GQ+ VAAK F L+ G V
Sbjct: 1776 LTVHGAQVLDSAIYSC-RVGAEGQDFPVQVEEVAAK-------FCRLLEPVCGELGGTVT 1827
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L C L ++ W+ N L R M + L + G EDAG Y +++
Sbjct: 1828 LACE-LSPACAEVVWRCGNTQL-RVGKRFQMVAEG-PVRSLTVLGLRAEDAGEYVCESRD 1884
Query: 1089 EAGIVSCTARLDVYISR 1105
+ +A+L V + R
Sbjct: 1885 D----HTSAQLTVSVPR 1897
Score = 57.8 bits (138), Expect = 6e-08
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 15/201 (7%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP F +EL + G+ V L CRV G P + W++ G +Q P +++ +
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIE-------D 6065
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV----TSANTENCSYESMGESN 555
P+ C L++ D+G + C A + G+ ++ +++V N S GE
Sbjct: 6066 PDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVEGEDA 6125
Query: 556 NDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHP 615
P P + ++ Q ++ P GL L + AA +E G++
Sbjct: 6126 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL----LVLVIRAASKEDLGLYE 6181
Query: 616 SRGVNGLINGKANSNKSLPTP 636
VN L + +A++ + +P
Sbjct: 6182 CELVNRLGSARASAELRIQSP 6202
Score = 57.4 bits (137), Expect = 7e-08
Identities = 33/112 (29%), Positives = 54/112 (48%), Gaps = 6/112 (5%)
Query: 429 CRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
C G PP F +++ + EG+ C + GAP Q++W++ G+ + F+
Sbjct: 6096 CSTLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 6155
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
L +PRS + LVI ED G++ C N GSA ++A+L + S
Sbjct: 6156 TL-SEPRS-----GLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201
Score = 57.0 bits (136), Expect = 1e-07
Identities = 184/886 (20%), Positives = 312/886 (35%), Gaps = 159/886 (17%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
+ G EC T V W+ +G EL ++ + + + G H L+ A D G
Sbjct: 808 DAVAGGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEG 866
Query: 341 RYTCLATNPSGSDTTSAEVFI---------EGASSTDSDSESLAFKSRAGAMPQAQKKTT 391
Y+C G D+ + + E + +E+ A + + + QAQ + T
Sbjct: 867 TYSCRV----GEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVT 922
Query: 392 --SVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF------PPVF 443
+ SSS T + L V Y C G ++ VF
Sbjct: 923 WYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVF 982
Query: 444 TKEL---QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
K+ G L C V A +V W++ G ++ S + K R
Sbjct: 983 AKDQVAHSEVQAEAGASATLSCEVAQA-QTEVMWYKDGKKLSSSLKVHVEAKGCRR---- 1037
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGS----ATSTAQLVVTSANTENCSYESMGES-- 554
LV+ + DAG ++C AR S T + + N G S
Sbjct: 1038 ----RLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAM 1093
Query: 555 -NNDHFQHFPPPPPILETSSLELASKKPSEIQQVNN----PELGLSRA--------ALQM 601
+ + Q + L +SK E++ P+ G + A ++
Sbjct: 1094 LSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRV 1153
Query: 602 QFNAAERETNGVH-PSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKK 660
F+ E GV + V+ + +A T A+L +P + K G KK
Sbjct: 1154 SFHLHITEPKGVFAKEQSVHNEVQAEAG------TTAMLSCEVAQPQTEVTWYKDG--KK 1205
Query: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMAR-RLLGADSAT 719
S ++++ E++G ++ K E G R++++ + + + A
Sbjct: 1206 LSSSSKVRM--EVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQL 1263
Query: 720 VFNIQEPEE--------ETANQEYKVSSCE--QRLISEIEYRLE-----RSPVDESGDEV 764
V N E E A + +V+ + ++L S + R+E R V + +
Sbjct: 1264 VHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQA 1323
Query: 765 QYGDVPVENG-------------MAPFFEMKLKHYKI--FEGMPVTFTCRVAGNPKPKIY 809
G+ E G A F + +L H K+ G T +C VA + ++
Sbjct: 1324 DAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVA-QAQTEVT 1382
Query: 810 WFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ 869
W+KDGK++S S M A + CT RL+VQ
Sbjct: 1383 WYKDGKKLSSSSK---------------------------VRMEA-----VGCTRRLVVQ 1410
Query: 870 AVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCR 929
Q + +G R S D EP + F + + ++ Q G
Sbjct: 1411 QACQ------ADTGEYSCEAGGQRLSFSLDVAEP-KVVFAKEQPVHR--EVQAQAGASTT 1461
Query: 930 MDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR 989
+ C+V+ T ++ W DGK + S +M L+++ AG Y+C
Sbjct: 1462 LSCEVAQAQT-EVMWYKDGKKLSFSSKVRM-EAVGCTRRLVVQQAGQAVAGEYSC----E 1515
Query: 990 AGQNSFSLELVVAAKEAHKPPVFIEK---LQNTGVADGYPVRLECRVLGVPPPQIFWKKE 1046
AG S L VA +A VF ++ + G L C V ++ W K+
Sbjct: 1516 AGSQRLSFHLHVAEPKA----VFAKEQPASREVQAEAGTSATLSCEV-AQAQTEVTWYKD 1570
Query: 1047 NESLTHSTDRVSMHQDNHGYIC---LLIQGATKEDAGWYTVSAKNE 1089
+ L+ S+ +V M C L++Q A + DAG Y+ A ++
Sbjct: 1571 GKKLS-SSSKVRMEAVG----CTRRLVVQEAGQADAGEYSCKAGDQ 1611
Score = 57.0 bits (136), Expect = 1e-07
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCE-GGDLHTL 329
PRF+ K+R+ EG C + G P P++RW+ +G L Q E L L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE 362
+I A ++D G Y C N GS SAE+ I+
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQ 6200
Score = 53.9 bits (128), Expect = 8e-07
Identities = 65/288 (22%), Positives = 108/288 (37%), Gaps = 30/288 (10%)
Query: 263 SALHFPAAP-RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC 321
+AL AP F +KL Q V E S V LE +T P P +RW L +++IH
Sbjct: 1979 AALRVREAPVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHA 2037
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE--------GASSTDSDSES 373
EG H L++ D G + C + D T A++ +E G + ++ +
Sbjct: 2038 EGA-RHRLVLHNVGFADRGFFGC----ETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQG 2092
Query: 374 LAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDG 433
A + T L + L++ + + + +G
Sbjct: 2093 TATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEG 2152
Query: 434 TTTA------YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
T+ P F++ LQ+ E + V LEC + P + V+W + G E++
Sbjct: 2153 VHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAG--- 2208
Query: 488 RILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535
K + A +L I D G++ C A + SA+ Q
Sbjct: 2209 -----KTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQ 2251
Score = 52.8 bits (125), Expect = 2e-06
Identities = 41/149 (27%), Positives = 70/149 (46%), Gaps = 12/149 (8%)
Query: 941 DLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 1000
++ W L+G P+ DS H+ + + H+L+++ + DAGI A++ S LE+
Sbjct: 2587 EVEWSLNGMPLYNDSFHE-ISHKGRRHTLVLKSIQRADAGIVR--ASSLKVSTSARLEVR 2643
Query: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
V KP VF++ L + + + L+C V P + W+K+ L S +H
Sbjct: 2644 V------KPVVFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLH 2696
Query: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
G L++ + EDAG YT +E
Sbjct: 2697 --TAGTRGLVVHDVSPEDAGLYTCHVGSE 2723
Score = 52.8 bits (125), Expect = 2e-06
Identities = 27/108 (25%), Positives = 48/108 (44%), Gaps = 7/108 (6%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL------HNTPDIQIHCEGG 324
PR +++ ++V +GS + +V G P P V W E E +TP +
Sbjct: 5371 PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV-ASSA 5429
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372
H+L++ + G YTC+A+N +G SA + + G + +
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEK 5477
Score = 52.4 bits (124), Expect = 2e-06
Identities = 72/284 (25%), Positives = 110/284 (38%), Gaps = 33/284 (11%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F + L+S + EGS L+C ++ PT V W G +L + +G L+
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCELS-EPTATVVWSKGGLQLQANGRREPRLQGCTAE-LV 3947
Query: 331 IAEAFEDDTGRYTCLATNPSGSDT---TSAEV-FIEGASSTDSDSESLAF----KSRAGA 382
+ + +DTG YTC + + S T T+A V F+ + D A SRAGA
Sbjct: 3948 LQDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGA 4007
Query: 383 MPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT------TT 436
+ +K SL + + V L V + Y C T +
Sbjct: 4008 SVEWRKG----SLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSV 4063
Query: 437 AYFPPVFTKELQNTAVAEGQVVVLECRVRGAPP-LQVQWFRQGSEIQDSPDFRILQKKPR 495
P F LQ+ G + L C++ A VQW ++G E+ P + + R
Sbjct: 4064 RVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEM-----R 4118
Query: 496 STAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT 539
S E L+I + +D G + C G + A L VT
Sbjct: 4119 SQGATRE---LLIHQLEAKDTGEYACVT----GGQKTAASLRVT 4155
Score = 52.0 bits (123), Expect = 3e-06
Identities = 63/277 (22%), Positives = 103/277 (37%), Gaps = 29/277 (10%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
RF + L+ EV EG L C ++ P V+W C G + D + G + L++
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP-VKW-CYGNNVLRPGDKYSLRQEGAMLELVV 3243
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG--ASSTDSDSESLAFKSRAGAMPQAQKK 389
D+GRY+C G TTSA + + A A + + K
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELSK 3299
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVH-------SPTSYLCRPDGTTTAY---- 438
V GS + + G + Q ++ Q+ + S +C + T+ +
Sbjct: 3300 AAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRP 3359
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
P F L++ EG L C + A P V+W + ++D S
Sbjct: 3360 MPAHFIGRLRHQESIEGATATLRCELSKAAP--VEWRKGRESLRDG--------DRHSLR 3409
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535
+ +C L I DAG ++C + SAT T +
Sbjct: 3410 QDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVK 3446
Score = 52.0 bits (123), Expect = 3e-06
Identities = 48/189 (25%), Positives = 81/189 (42%), Gaps = 25/189 (13%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
D V + C+VS + W L G P++ + ++ VR+ +H+L ++ VT D
Sbjct: 4167 DAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPED 4226
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPP 1038
AG + G ++ S +L V A E +E LQ+ +++G +CR+
Sbjct: 4227 AG----TVSFHLGNHASSAQLTVRAPEV----TILEPLQDVQLSEGQDASFQCRLSRASG 4278
Query: 1039 PQIFWK------KENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGI 1092
+ W + NE + ++ ++H L + T EDAG TVS G
Sbjct: 4279 QEARWALGGVPLQANEMNDITVEQGTLH-------LLTLHKVTLEDAG--TVSF--HVGT 4327
Query: 1093 VSCTARLDV 1101
S A+L V
Sbjct: 4328 CSSEAQLKV 4336
Score = 52.0 bits (123), Expect = 3e-06
Identities = 42/172 (24%), Positives = 70/172 (40%), Gaps = 17/172 (9%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
Q AL P F ++L G V L CRVTG P P + W+ +GK + P I
Sbjct: 6003 QQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPH-HI 6061
Query: 320 HCEGGDLHTLIIAEAFED-DTGRYTCLATNPSGSDTTSAEVFIE----------GASSTD 368
E D +I ++ D+G+Y C A + +G+ +T ++ ++ + +
Sbjct: 6062 LIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVE 6121
Query: 369 SDSESLAFKSRAGAMPQAQKKTTSVSLTIGS-----SSPKTGVTTAVIQPLS 415
+ PQ + LT G+ S P++G+ VI+ S
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAAS 6173
Score = 51.6 bits (122), Expect = 4e-06
Identities = 69/282 (24%), Positives = 108/282 (38%), Gaps = 32/282 (11%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P FI +LR QE EG+ L C + + V W +G+E D + G +
Sbjct: 3359 PMPAHFIGRLRHQESIEGATATLRCEL--SKAAPVEW-RKGRESLRDGDRHSLRQDGAVC 3415
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG--ASSTDSDSESLAFKSRAGAMPQ 385
L I D G Y+C+ G + TSA + ++ A T+ A + +
Sbjct: 3416 ELQICGLAVADAGEYSCVC----GEERTSATLTVKALPAKFTEGLRNEEAVEGATAMLWC 3471
Query: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQ-----PLSVPVQQVHSPTSYLC-----RPDGT- 434
K V G + + G + Q L + + YLC R T
Sbjct: 3472 ELSKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATL 3531
Query: 435 TTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE-IQDSPDFRILQKK 493
T P F ++++N EG VL+C + A P V+W R+GSE ++D + + Q
Sbjct: 3532 TIRALPARFIEDVKNQEAREGATAVLQCELNSAAP--VEW-RKGSETLRDGDRYSLRQDG 3588
Query: 494 PRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535
+ C L I D G ++C + SA T +
Sbjct: 3589 TK--------CELQIRGLAMADTGEYSCVCGQERTSAMLTVR 3622
Score = 51.6 bits (122), Expect = 4e-06
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P+F+ +T G + LEC V ++ +W + G E+ D I Q
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG------- 4950
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQ 560
+ C+L+I DAG +TC N +G T +A +VV+ + +E + S G +D F+
Sbjct: 4951 DGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESE--AESSSGGELDDAFR 5008
Score = 50.8 bits (120), Expect = 7e-06
Identities = 48/190 (25%), Positives = 81/190 (42%), Gaps = 13/190 (6%)
Query: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
+P F + L +EG + C++S PT + W G ++ + + + + L
Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCELSE-PTATVVWSKGGLQLQANGRREPRL-QGCTAEL 3946
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
+++ + D G YTC G + S L V A P F+ +LQ+ V +G L
Sbjct: 3947 VLQDLQREDTGEYTCTC----GSQATSATLTVTAA----PVRFLRELQHQEVDEGGTAHL 3998
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
C L + W+K + L + M QD LL++G +EDAG YT +
Sbjct: 3999 CCE-LSRAGASVEWRKGSLQLFPCA-KYQMVQDGAAAE-LLVRGVEQEDAGDYTCDTGHT 4055
Query: 1090 AGIVSCTARL 1099
+ S + R+
Sbjct: 4056 QSMASLSVRV 4065
Score = 49.7 bits (117), Expect = 2e-05
Identities = 74/326 (22%), Positives = 123/326 (37%), Gaps = 65/326 (19%)
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
M F +L+H + EG T C ++ + W K G++ D +++++D C
Sbjct: 3360 MPAHFIGRLRHQESIEGATATLRCELS--KAAPVEWRK-GRESLRDGDRHSLRQD-GAVC 3415
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 894
L + D G Y+ + + R S T L V+A+ +
Sbjct: 3416 ELQICGLAVADAGEYSCVCG--EERTSAT--LTVKALPAK-------------------- 3451
Query: 895 RDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
F + + EG + C++S + + W+ + +R
Sbjct: 3452 ------------------FTEGLRNEEAVEGATAMLWCELSKVAP--VEWRKGPENLR-- 3489
Query: 955 SAHKMLVRENGVH-SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI 1013
+ ++R+ G L I + DAG Y C+ GQ S L + A A FI
Sbjct: 3490 DGDRYILRQEGTRCELQICGLAMADAGEYLCVC----GQERTSATLTIRALPAR----FI 3541
Query: 1014 EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC-LLIQ 1072
E ++N +G L+C + P + W+K +E+L DR S+ QD G C L I+
Sbjct: 3542 EDVKNQEAREGATAVLQCELNSAAP--VEWRKGSETL-RDGDRYSLRQD--GTKCELQIR 3596
Query: 1073 GATKEDAGWYTVSAKNEAGIVSCTAR 1098
G D G Y+ E T R
Sbjct: 3597 GLAMADTGEYSCVCGQERTSAMLTVR 3622
Score = 49.7 bits (117), Expect = 2e-05
Identities = 67/277 (24%), Positives = 107/277 (38%), Gaps = 30/277 (10%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+F + LR++E EG+ L C ++ V W +G E D I + G L I
Sbjct: 3451 KFTEGLRNEEAVEGATAMLWCELS--KVAPVEWR-KGPENLRDGDRYILRQEGTRCELQI 3507
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD-SDSESLAFKSRAGAMPQAQKKT 390
D G Y C+ G + TSA + I + D ++ + A A+ Q + +
Sbjct: 3508 CGLAMADAGEYLCVC----GQERTSATLTIRALPARFIEDVKNQEAREGATAVLQCELNS 3563
Query: 391 TS-VSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT-------SYLCRPDGT----TTAY 438
+ V GS + + G ++ Q + Q+ S +C + T T
Sbjct: 3564 AAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRA 3623
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
P FT+ L+N EG VL C + P V+W++ ++D + Q R
Sbjct: 3624 LPIKFTEGLRNEEATEGATAVLRCELSKMAP--VEWWKGHETLRDGDRHSLRQDGAR--- 3678
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535
C L I EDAG + C + SA T +
Sbjct: 3679 -----CELQIRGLVAEDAGEYLCMCGKERTSAMLTVR 3710
Score = 49.7 bits (117), Expect = 2e-05
Identities = 30/96 (31%), Positives = 44/96 (45%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F GD Q G R++C V+ W DG + H + +G SL+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 1006
I + DAG YTC +N+ GQ + S +VV+ E+
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSES 4993
Score = 49.7 bits (117), Expect = 2e-05
Identities = 27/94 (28%), Positives = 42/94 (44%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P F K++ EG FTC + G P P+I W+KDG ++ + T+ G L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQA 870
A++ +D G Y N G + L +Q+
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201
Score = 49.3 bits (116), Expect = 2e-05
Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 1008 KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 1067
+PP F E+L + G V+L CRV G P P I W K+ +++ + + +D G
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHI-LIEDPDGSC 6070
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
L++ T D+G Y A + AG S ++ V +
Sbjct: 6071 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV 6106
Score = 48.9 bits (115), Expect = 3e-05
Identities = 60/280 (21%), Positives = 106/280 (37%), Gaps = 29/280 (10%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
I+ L +V EGS CR++ V WF + LH +I + G H L + +
Sbjct: 3008 IEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQ 3067
Query: 334 AFEDDTGRYTCLATNPSGSD----TTSAEVF---IEGASSTDSDSESLAFKSRAGAMPQA 386
D+G A + S T VF + A+ T+ + +L ++ +P
Sbjct: 3068 LALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVC 3127
Query: 387 QKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF------P 440
K T+ S+ L + + Y C G ++ P
Sbjct: 3128 WTKD---GKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARP 3184
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
F + L++ V EG L C V + V+W + ++ + + Q+
Sbjct: 3185 VRFQEALKDLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQE-------- 3235
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
+ LV+ P+D+G ++CS +G T++A L VT+
Sbjct: 3236 GAMLELVVRNLRPQDSGRYSCS----FGDQTTSATLTVTA 3271
Score = 47.8 bits (112), Expect = 6e-05
Identities = 66/275 (24%), Positives = 104/275 (37%), Gaps = 30/275 (10%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+FI KLR++E EG+ L C + + V W +G E D + G + L I
Sbjct: 3275 QFIGKLRNKEATEGATATLRCEL--SKAAPVEW-RKGSETLRDGDRYCLRQDGAMCELQI 3331
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIE--GASSTDSDSESLAFKSRAGAMPQAQKK 389
D Y+C+ G + TSA + I A + + + K
Sbjct: 3332 RGLAMVDAAEYSCVC----GEERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELSK 3387
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQV-------HSPTSYLCRPDGT----TTAY 438
V G S + G ++ Q +V Q+ S +C + T T
Sbjct: 3388 AAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKA 3447
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
P FT+ L+N EG +L C + P V+W + ++D + + Q+ R
Sbjct: 3448 LPAKFTEGLRNEEAVEGATAMLWCELSKVAP--VEWRKGPENLRDGDRYILRQEGTRCEL 3505
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATST 533
+IC L +A DAG + C + SAT T
Sbjct: 3506 ---QICGLAMA-----DAGEYLCVCGQERTSATLT 3532
Score = 47.8 bits (112), Expect = 6e-05
Identities = 72/291 (24%), Positives = 111/291 (38%), Gaps = 32/291 (10%)
Query: 263 SALHFPAAP-RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC 321
+ L AAP RF+++L+ QEV EG +L C ++ V W +L Q+
Sbjct: 3970 ATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELS-RAGASVEWRKGSLQLFPCAKYQM-V 4027
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEV----FIEGASSTDSDSESLA-- 375
+ G L++ ++D G YTC + + S V F S + ++ +A
Sbjct: 4028 QDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARL 4087
Query: 376 ----FKSRAGAMPQAQKKTTSVSLTIGSSSPKTGV-TTAVIQPLSVPVQQVHSPTSYLCR 430
+ +GA+ Q K+ V L G PK + + + L + + Y C
Sbjct: 4088 CCQLSDAESGAVVQWLKE--GVELHAG---PKYEMRSQGATRELLIHQLEAKDTGEYACV 4142
Query: 431 PDGTTTAYFPPVFTKE------LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDS 484
G TA V E L + V + V C V A VQW QG +Q +
Sbjct: 4143 TGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSN 4202
Query: 485 PDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535
+ + R I TL + PEDAG + N SA T +
Sbjct: 4203 EVTEVAVRDGR-------IHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVR 4246
Score = 45.4 bits (106), Expect = 3e-04
Identities = 33/109 (30%), Positives = 43/109 (39%), Gaps = 10/109 (9%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEI--QDSPDFRILQKKPRSTA 498
P F + V EG CRV G+P V W + G + D P R+
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRV--------E 161
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCS 547
E E L I P D G + A N G+A++ A LVV S + S
Sbjct: 162 ELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTAS 210
Score = 45.1 bits (105), Expect = 4e-04
Identities = 47/187 (25%), Positives = 69/187 (36%), Gaps = 13/187 (6%)
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
FL+A DL+ +E + C+VS P + W+ DG + P + L G L++
Sbjct: 2649 FLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKYDFL-HTAGTRGLVVH 2706
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK-LQNTGVADGYPVRLEC 1031
V+ DAG+YTC E A H V I K L+ V +G EC
Sbjct: 2707 DVSPEDAGLYTC---------HVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFEC 2757
Query: 1032 RVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
+ S+ R + YI L+++ A DAG S +
Sbjct: 2758 VLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYI-LVVREAAPSDAGEVVFSVRGLTS 2816
Query: 1092 IVSCTAR 1098
S R
Sbjct: 2817 KASLIVR 2823
Score = 45.1 bits (105), Expect = 4e-04
Identities = 70/276 (25%), Positives = 105/276 (38%), Gaps = 32/276 (11%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F ++L + EG + L C + P V W +GK L + Q+ EG L+I
Sbjct: 3098 FSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQ-LLIT 3155
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTS 392
A D+GRY C A S D E L G + +S
Sbjct: 3156 GATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVL-----EGGAATLRCVLSS 3210
Query: 393 VSLTI----GSSSPKTGVTTAVIQP---LSVPVQQVHSPTS--YLCR-PDGTTTA----- 437
V+ + G++ + G ++ Q L + V+ + S Y C D TT+A
Sbjct: 3211 VAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVT 3270
Query: 438 YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
P F +L+N EG L C + A P V+W R+GSE D L+
Sbjct: 3271 ALPAQFIGKLRNKEATEGATATLRCELSKAAP--VEW-RKGSETLRDGDRYCLR------ 3321
Query: 498 AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATST 533
+ +C L I DA ++C + SA+ T
Sbjct: 3322 -QDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLT 3356
Score = 44.7 bits (104), Expect = 5e-04
Identities = 55/248 (22%), Positives = 88/248 (35%), Gaps = 30/248 (12%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFED 337
R+ V EG L C VTG P P W +G+ + ++ + + L I +
Sbjct: 245 RTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQS 304
Query: 338 DTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTI 397
D G YTC A+N G +S V + ++ FK R + +K++ + +
Sbjct: 305 DRGLYTCTASNLVGQTYSSVLVVVR--------EPAVPFKKRLQDLEVREKESATFLCEV 356
Query: 398 GS---------------SSPKTGV-TTAVIQPLSVPVQQVHSPTSYLCR-PDGTTT---- 436
+S K G+ + L+V Y+C P+G+ T
Sbjct: 357 PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAEL 416
Query: 437 AYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRS 496
A + K + TAV G + C P V W R E+ I + R
Sbjct: 417 AVQGNLLRKLPRKTAVRVGDTAMF-CVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRH 475
Query: 497 TAEPEEIC 504
T + C
Sbjct: 476 TLTISQCC 483
Score = 44.3 bits (103), Expect = 6e-04
Identities = 35/161 (21%), Positives = 66/161 (40%), Gaps = 9/161 (5%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
D+ + EG+ C++S + W L G P++ + + + V + +H L + VT D
Sbjct: 4258 DVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLED 4317
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPP 1038
AG + G S +L V AK + L+N +G EC++
Sbjct: 4318 AG----TVSFHVGTCSSEAQLKVTAKN-----TVVRGLENVEALEGGEALFECQLSQPEV 4368
Query: 1039 PQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 1079
W ++E + S + + +N LL++ +D+
Sbjct: 4369 AAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDS 4409
Score = 43.5 bits (101), Expect = 0.001
Identities = 50/218 (22%), Positives = 79/218 (36%), Gaps = 14/218 (6%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
PAA I+ L Q VA G V L C ++ TP V W + K + + + CEG +
Sbjct: 2826 PAA--IIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEG-TMA 2881
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDT----TSAEVFIEGASSTDSDSESLAFKSRAGAM 383
L+I A D G YTC + + A F E ++ + + A +
Sbjct: 2882 MLVIRGASLKDAGEYTCEVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEH 2941
Query: 384 PQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPV- 442
P A L + +S + L++ + +Y C + V
Sbjct: 2942 PAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQ 3001
Query: 443 -----FTKELQNTAVAEGQVVVLECRVRGAPPLQVQWF 475
++L++ V EG CR+ A V WF
Sbjct: 3002 GRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWF 3039
Score = 43.1 bits (100), Expect = 0.001
Identities = 65/266 (24%), Positives = 99/266 (37%), Gaps = 59/266 (22%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F + L+ E +V LEC ++ P VRW +G EL + I +G +L I
Sbjct: 2168 FSRPLQDVVTTEKEKVTLECELS-RPNVDVRWLKDGVELRAGKTMAIAAQGA-CRSLTIY 2225
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTS 392
D G Y C A + +SA V ++G + T LA AG + + S
Sbjct: 2226 RCEFADQGVYVCDAHDAQ----SSASVKVQGRTYTLIYRRVLA--EDAGEIQFVAENAES 2279
Query: 393 VSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAV 452
A ++ +PV L RP L++
Sbjct: 2280 ---------------RAQLRVKELPVT--------LVRP---------------LRDKIA 2301
Query: 453 AEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETF 512
E VLEC+V A QV+WF+ E+Q P + ++ L+I++
Sbjct: 2302 MEKHRGVLECQVSRASA-QVRWFKGSQELQPGPKYELVSDGLYR--------KLIISDVH 2352
Query: 513 PEDAGIFTCSARNDYGSATSTAQLVV 538
ED +TC D G ++AQ V
Sbjct: 2353 AEDEDTYTC----DAGDVKTSAQFFV 2374
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 9/142 (6%)
Query: 942 LSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
++W DG+ + P +++ G L++ V DAG+Y C+ +R G+ ++ L +
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASA-GRRVLLVRDVARDDAGLYECV--SRGGRIAYQLSVQG 793
Query: 1002 AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQ 1061
A+ HK G P + EC + W K+ L HS +R + +
Sbjct: 794 LARFLHKDMAG----SCVDAVAGGPAQFECET-SEAHVHVHWYKDGMELGHSGERF-LQE 847
Query: 1062 DNHGYICLLIQGATKEDAGWYT 1083
D L+ T++D G Y+
Sbjct: 848 DVGTRHRLVAATVTRQDEGTYS 869
Score = 42.4 bits (98), Expect = 0.002
Identities = 66/304 (21%), Positives = 111/304 (36%), Gaps = 42/304 (13%)
Query: 238 GARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGN 297
G C +Q L+ H + P+ A PA+ R + G+ L C V
Sbjct: 1510 GEYSCEAGSQRLSF-HLHVAEPKAVFAKEQPAS-------REVQAEAGTSATLSCEVAQA 1561
Query: 298 PTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSA 357
T V W+ +GK+L ++ +++ G L++ EA + D G Y+C A G S
Sbjct: 1562 QT-EVTWYKDGKKLSSSSKVRMEAVGCT-RRLVVQEAGQADAGEYSCKA----GDQRLSF 1615
Query: 358 EVFI---------EGASSTDSDSESLAFKSRAGAMPQAQKKTT--SVSLTIGSSSPKTGV 406
+ + E + + +E+ A + + + QAQ + T + SSS
Sbjct: 1616 HLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVE 1675
Query: 407 TTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT---------AVAEGQV 457
+ L V Y C G ++ V E Q + V E +
Sbjct: 1676 AVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEPQISERPCRREPLVVKEHED 1735
Query: 458 VVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAG 517
++L + V W + G EI+ S K TA + TL + D+
Sbjct: 1736 IILTATLATPSAATVTWLKDGVEIRRS--------KRHETASQGDTHTLTVHGAQVLDSA 1787
Query: 518 IFTC 521
I++C
Sbjct: 1788 IYSC 1791
Score = 40.8 bits (94), Expect = 0.007
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
Query: 787 KIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ-----ISPKSDHYTIQRDLDGTCSLHTTAS 841
K+ +G +TF+ +V G P P ++W ++ + I P + YT+ SL
Sbjct: 5381 KVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH-SLVLLDV 5439
Query: 842 TLDDDGNYTIMAANPQGRISCTGRLMVQAV 871
G YT +A+N G+ C+ L V +
Sbjct: 5440 GRQHQGTYTCIASNAAGQALCSASLHVSGL 5469
Score = 39.7 bits (91), Expect = 0.016
Identities = 64/275 (23%), Positives = 104/275 (37%), Gaps = 33/275 (12%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V E + L + V W +G E+ + + +G D HTL + A D+
Sbjct: 1730 VKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQG-DTHTLTVHGAQVLDSAI 1788
Query: 342 YTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTI---G 398
Y+C G++ V +E ++ G + A + + + + + G
Sbjct: 1789 YSCRV----GAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACAEVVWRCG 1844
Query: 399 SSSPKTG-----VTTAVIQPLSVPVQQVHSPTSYLC--RPDGTT---TAYFPPV--FTKE 446
++ + G V ++ L+V + Y+C R D T+ T P V F
Sbjct: 1845 NTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSG 1904
Query: 447 LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTL 506
L EG +C V + + V WFR G+ +Q S F I Q +L
Sbjct: 1905 LSTVVAEEGGEATFQCVVSPSD-VAVVWFRDGALLQPSEKFAISQSGASH--------SL 1955
Query: 507 VIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA 541
I++ EDAG T A A+S+A L V A
Sbjct: 1956 TISDLVLEDAGQITVEAE----GASSSAALRVREA 1986
Score = 39.7 bits (91), Expect = 0.016
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
P+F +T G +RLEC V + W K+ LT + Q G L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHH-HIDQLGDGTCSL 4956
Query: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTA 1097
LI G + DAG YT N+ G V+ +A
Sbjct: 4957 LITGLDRADAGCYTCQVSNKFGQVTHSA 4984
Score = 38.5 bits (88), Expect = 0.036
Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 8/98 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P F + V+ G+ L C++ G P QV W + + FR+ A+
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRL--------AQD 61
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ L I + D+G + C ARN G A + L V
Sbjct: 62 GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 38.5 bits (88), Expect = 0.036
Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 9/82 (10%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
P VF K L + + E + L+C V P V W + G ++ S + L TA
Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKYDFLH-----TAG 2699
Query: 500 PEEICTLVIAETFPEDAGIFTC 521
LV+ + PEDAG++TC
Sbjct: 2700 TRG---LVVHDVSPEDAGLYTC 2718
Score = 37.7 bits (86), Expect = 0.061
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 24/164 (14%)
Query: 944 WQLDGKPVRPDSAHKMLVRENGV-HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA 1002
W DG + S + L + G H L+ VT +D G Y+C R G++S L V+
Sbjct: 830 WYKDGMELG-HSGERFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRVS 884
Query: 1003 AKEA--HKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
+ K + KLQ G L C V ++ W K+ + L+ S+ +V M
Sbjct: 885 EPKVVFAKEQLARRKLQ---AEAGASATLSCEV-AQAQTEVTWYKDGKKLS-SSSKVCME 939
Query: 1061 QDNHGYIC---LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
C L++Q A + DAG Y+ EAG + LDV
Sbjct: 940 ATG----CTRRLVVQQAGQADAGEYSC----EAGGQRLSFHLDV 975
Score = 37.4 bits (85), Expect = 0.079
Identities = 44/167 (26%), Positives = 68/167 (40%), Gaps = 17/167 (10%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
D V G+ + C++S TP + W D K +R + + V E + L+I + +D
Sbjct: 2835 DQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDV-VCEGTMAMLVIRGASLKD 2892
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPP 1038
AG YTC A +++ SL + K F E+L N V + C+ P
Sbjct: 2893 AGEYTCEV--EASKSTASLHV------EEKANCFTEELTNLQVEEKGTAVFTCKT-EHPA 2943
Query: 1039 PQIFWKKENESLTHSTDRVSMHQDNHGYIC--LLIQGATKEDAGWYT 1083
+ W+K L S HQ + + L I K D+ YT
Sbjct: 2944 ATVTWRKGLLELRAS----GKHQPSQEGLTLRLTISALEKADSDTYT 2986
Score = 33.9 bits (76), Expect = 0.88
Identities = 35/158 (22%), Positives = 64/158 (40%), Gaps = 11/158 (6%)
Query: 941 DLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 1000
++ W+ +R +M V E V SL + + + DAG Y C + + S +L
Sbjct: 1838 EVVWRCGNTQLRVGKRFQM-VAEGPVRSLTVLGLRAEDAGEYVC----ESRDDHTSAQLT 1892
Query: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
V+ K F+ L +G +C V+ + W ++ +L +++ ++
Sbjct: 1893 VSVPRVVK---FMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDG-ALLQPSEKFAIS 1947
Query: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTAR 1098
Q + L I EDAG TV A+ + + R
Sbjct: 1948 QSGASH-SLTISDLVLEDAGQITVEAEGASSSAALRVR 1984
Score = 33.1 bits (74), Expect = 1.5
Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 5/91 (5%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQ-IHCEGGDLHTLIIA 332
++ L + E EG EC+++ W + + +H + + + + E G H L++
Sbjct: 4343 VRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLK 4402
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
D+ R T LA G TSA + + G
Sbjct: 4403 NLRPQDSCRVTFLA----GDMVTSAFLTVRG 4429
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 907 RFFRPHFLQAPGDLTVQEGKLCRMDCKVS-GLPTPDLSWQLDGKPVRPDSAHKMLVRENG 965
R +R L+ + V+ G C +S +P + SW ++G V+PD + + +
Sbjct: 4428 RGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGS 4487
Query: 966 VHSLIIEPVTSRDAGIYT 983
H+L++ AG T
Sbjct: 4488 HHALLLRSAQPHHAGEVT 4505
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 122 bits (307), Expect = 1e-27
Identities = 101/350 (28%), Positives = 146/350 (41%), Gaps = 32/350 (9%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F +L++ ++ +G PV+F C V G P P + WFKDGK + + DHY I D G
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLE-EDDHYMINEDQQGGHQ 5183
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVN---QRGRSPRSPSGHPHVRRPRS 892
L TA D G Y +A N G S L V + S + + S
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEG-KLCRMDCKVSGLPTPDLSWQLDGKPV 951
G E+ + + P ++ DL V G +L + KV G P P L W DG+P+
Sbjct: 5244 SREQEGTESTTDEGQL--PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPL 5301
Query: 952 RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV---------A 1002
SAH + + +H+L I VT D+G Y +N G S L+V
Sbjct: 5302 TA-SAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKP 5360
Query: 1003 AKEAHK---PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSM 1059
A + H+ PP +E+ V G + +V G P P + W +E + +
Sbjct: 5361 ASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA----ERGVLWI 5416
Query: 1060 HQDNHGYI--------CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
D GY L++ ++ G YT A N AG C+A L V
Sbjct: 5417 GPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466
Score = 108 bits (269), Expect = 4e-23
Identities = 59/191 (30%), Positives = 97/191 (50%), Gaps = 5/191 (2%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F + D T + G+ ++ C+V+G P P +SW DGK V+ D H ++ +G +LI
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLE 1030
++ +T D+G Y C A + AG S +++V PP F+ K++ + +G +
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV-----PPRFVNKVRASPFVEGEDAQFT 6128
Query: 1031 CRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEA 1090
C + G P PQI W K+ LT ++ + G + L+I+ A+KED G Y N
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188
Query: 1091 GIVSCTARLDV 1101
G +A L +
Sbjct: 6189 GSARASAELRI 6199
Score = 105 bits (262), Expect = 2e-22
Identities = 82/280 (29%), Positives = 124/280 (44%), Gaps = 21/280 (7%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F ++ ++ EG TF CRV G+P+P + W KDG+++ +L +
Sbjct: 109 APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRLMV--QAVNQRGRSPRSPSG-HPHVRRPRS 892
L A+ D G Y + A NP G S L+V A + R S + H++R R
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRRE 228
Query: 893 RSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR 952
R G P TV EGK R+ C V+G P P+ W+ DG+ V
Sbjct: 229 AMRAEGAPASPPS---------TGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVT 279
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSR--DAGIYTCIATNRAGQNSFSLELVVAAKEAHKPP 1010
H +V E+ + +++ + + D G+YTC A+N GQ S+ +VV +E P
Sbjct: 280 EGRRH--VVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVV--REPAVP- 334
Query: 1011 VFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESL 1050
F ++LQ+ V + C V P + W KE L
Sbjct: 335 -FKKRLQDLEVREKESATFLCEV-PQPSTEAAWFKEETRL 372
Score = 98.6 bits (244), Expect = 3e-20
Identities = 95/353 (26%), Positives = 134/353 (37%), Gaps = 65/353 (18%)
Query: 768 DVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQ 827
D P +G AP F + K + + G T +C++ GNP P++ W KD + ++ + + +
Sbjct: 2 DQPQFSG-APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGA-RFRLA 59
Query: 828 RDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHV 887
+D D L L D G Y A N G L V A
Sbjct: 60 QDGD-LYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQA--------- 109
Query: 888 RRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLD 947
PHFL P + V+EG C+V G P P +SW D
Sbjct: 110 -----------------------PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKD 146
Query: 948 GKPVRPDSAHKMLVRENGVHSLI-IEPVTSRDAGIYTCIATNRAGQNSFSLELVV---AA 1003
G+ + ++ V E G S + I RD G Y A N G S + LVV AA
Sbjct: 147 GRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAA 206
Query: 1004 KEAHKP----PVFIEKLQ----------------NTG-----VADGYPVRLECRVLGVPP 1038
A +P + LQ +TG V +G RL C V G P
Sbjct: 207 DTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPK 266
Query: 1039 PQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
P+ WKK+ + +T V +++D L I + D G YT +A N G
Sbjct: 267 PETVWKKDGQLVTEGRRHV-VYEDAQENFVLKILFCKQSDRGLYTCTASNLVG 318
Score = 98.6 bits (244), Expect = 3e-20
Identities = 83/287 (28%), Positives = 126/287 (43%), Gaps = 56/287 (19%)
Query: 259 PQP-HSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDI 317
P+P S L AAP F+ +L++QEV +G V +C VTG P P VRWF +GK L
Sbjct: 5113 PEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHY 5172
Query: 318 QIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSD-----SE 372
I+ + H LII D G Y CLA N G +T AE+ ++ +STD D +E
Sbjct: 5173 MINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVD-LTSTDYDTAADATE 5231
Query: 373 SLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPD 432
S ++ S G + +++ T +
Sbjct: 5232 SSSYFSAQGYLSSREQEGT----------------------------------------E 5251
Query: 433 GTTTAYFPPVFTKELQNTAVAEG-QVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQ 491
TT P +EL++ VA G ++ + +V+G P ++ WF+ G + S R+
Sbjct: 5252 STTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTD 5311
Query: 492 KKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
KK + TL I ED+G + N G+A S+A+L+V
Sbjct: 5312 KK--------ILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV 5350
Score = 86.3 bits (212), Expect = 1e-16
Identities = 59/193 (30%), Positives = 86/193 (44%), Gaps = 3/193 (1%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P FL P V GK + C++ G PTP +SW+ D +PV A L ++ ++ L
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAA-GARFRLAQDGDLYRLT 68
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKE--AHKPPVFIEKLQNTGVADGYPVR 1028
I + D+G Y C A N G+ ++ L V A+ A + P F+ + + V +G
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEAT 128
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
CRV G P P + W K+ L ++ L I+ A D G Y V A+N
Sbjct: 129 FRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAEN 188
Query: 1089 EAGIVSCTARLDV 1101
G S A L V
Sbjct: 189 PLGAASAAAALVV 201
Score = 86.3 bits (212), Expect = 1e-16
Identities = 62/224 (27%), Positives = 86/224 (38%), Gaps = 41/224 (18%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P FE +L G V CRV G PKP I W+KDGK + H I+ D DG+C+L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIE-DPDGSCAL 6072
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
+ T D G Y AA+ G S G+++VQ
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV-------------------------- 6106
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956
P F+ EG+ + C + G P P + W DG + +
Sbjct: 6107 -------------PPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNK 6153
Query: 957 HKMLVR-ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL 999
+ L +G+ L+I + D G+Y C NR G S EL
Sbjct: 6154 FQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAEL 6197
Score = 76.6 bits (187), Expect = 1e-13
Identities = 80/329 (24%), Positives = 123/329 (37%), Gaps = 42/329 (12%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYT 850
G + C VA + W KDG +++ H+ Q DGTCSL T D G YT
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG-DGTCSLLITGLDRADAGCYT 4970
Query: 851 IMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFR 910
+N G+++ + ++V S RR R R FR
Sbjct: 4971 CQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARR-----------LHRLFR 5019
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL- 969
++P +++ +E L + P WQ + H + +R +
Sbjct: 5020 ---TKSPAEVSDEELFLSADEGPAE--PEEPADWQ-----TYREDEHFICIRFEALTEAR 5069
Query: 970 -IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP----------------PVF 1012
+ A + + Q +E+ + +KE P PVF
Sbjct: 5070 QAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCI-SKETPAPVVPPEPLPSLLTSDAAPVF 5128
Query: 1013 IEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQ 1072
+ +LQN V DGYPV +C V G P P + W K+ + L D +++D G L+I
Sbjct: 5129 LTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGK-LLEEDDHYMINEDQQGGHQLIIT 5187
Query: 1073 GATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
D G Y A+N G+ S A L V
Sbjct: 5188 AVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 76.6 bits (187), Expect = 1e-13
Identities = 60/249 (24%), Positives = 100/249 (40%), Gaps = 30/249 (12%)
Query: 760 SGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVT-FTCRVAGNPKPKIYWFKDGKQIS 818
S E + + + G P +L+ ++ G + F +V G P P++YWFKDG+ ++
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLT 5302
Query: 819 PKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSP 878
+ + + T L + T +D G Y +N G + RL+V+ ++ P
Sbjct: 5303 ASAHIRMTDKKILHT--LEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKP 5360
Query: 879 RSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLP 938
S + E+ P L+ V++G KV G P
Sbjct: 5361 ASD----------------------VHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRP 5398
Query: 939 TPDLSWQLDGKP-----VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN 993
P + W + + PD+ + HSL++ V + G YTCIA+N AGQ
Sbjct: 5399 VPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQA 5458
Query: 994 SFSLELVVA 1002
S L V+
Sbjct: 5459 LCSASLHVS 5467
Score = 76.6 bits (187), Expect = 1e-13
Identities = 86/354 (24%), Positives = 131/354 (37%), Gaps = 89/354 (25%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCE-GGDLHTL 329
PRF+ K+R+ EG C + G P P++RW+ +G L Q E L L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG---ASSTDSDSESLAFKSRAGAMPQA 386
+I A ++D G Y C N GS SAE+ I+ + E L + +A
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERA 6227
Query: 387 QKKTTSV---------------SLT--------------IGSSSPKTGVTTA------VI 411
++ TSV LT GS P TG + A V
Sbjct: 6228 DQEVTSVLKRLLGPKAPGPSTGDLTGPGPCPRGAPALQETGSQPPVTGTSEAPAVPPRVP 6287
Query: 412 QPL------------------SVPVQ----------------QVHS-------PTSYLCR 430
QPL +VP++ VHS +Y +
Sbjct: 6288 QPLLHEGPEQEPEAIARAQEWTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQ 6347
Query: 431 PDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
T TA PP +++ G E + G P V W++ ++ DS R+
Sbjct: 6348 AIDTHTAR-PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDST--RLS 6404
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTE 544
Q++ +T +LV+ +DAG++TC A+N G A+L+V + E
Sbjct: 6405 QQQEGTT------YSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNE 6452
Score = 72.4 bits (176), Expect = 2e-12
Identities = 98/471 (20%), Positives = 170/471 (36%), Gaps = 79/471 (16%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
PP F +EL + G+ V L CRV G P + W++ G +Q P +++ +
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIE-------D 6065
Query: 500 PEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV----TSANTENCSYESMGESN 555
P+ C L++ D+G + C A + G+ ++ +++V N S GE
Sbjct: 6066 PDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVEGEDA 6125
Query: 556 NDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHP 615
P P + ++ Q ++ P GL L + AA +E G++
Sbjct: 6126 QFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL----LVLVIRAASKEDLGLYE 6181
Query: 616 SRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQG 675
VN L + +A++ + +P + L+A D ++
Sbjct: 6182 CELVNRLGSARASAELRIQSPMLQAQEQCHREQLVA---------------AVEDTTLER 6226
Query: 676 TKDAVIQDLERKLRFKE------DLLNNG--------------QPRLT-------YEERM 708
V L+R L K DL G QP +T R+
Sbjct: 6227 ADQEVTSVLKRLLGPKAPGPSTGDLTGPGPCPRGAPALQETGSQPPVTGTSEAPAVPPRV 6286
Query: 709 ARRLLGADSATVFNIQEPEEETANQEYKV----------SSCEQRLISEIEYRLERSPVD 758
+ LL QEPE QE+ V + L+ ++ + R
Sbjct: 6287 PQPLLHEGPE-----QEPEAIARAQEWTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQ 6341
Query: 759 ESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQIS 818
+ Y + P ++ ++ + G F + G+P+P + W+KD Q+
Sbjct: 6342 RT---YTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQL- 6397
Query: 819 PKSDHYTIQRDLDGTC-SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
D + + +GT SL D G YT +A N G++ C L+V
Sbjct: 6398 --VDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 6446
Score = 67.8 bits (164), Expect = 5e-11
Identities = 65/271 (23%), Positives = 101/271 (37%), Gaps = 53/271 (19%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEG-GDLHT 328
AP F+ + S V EGS CRV G+P P V W +G+ L ++ E G+
Sbjct: 109 APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168
Query: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQK 388
L I A D G Y A NP G+ + +A + ++ S +D+ S S A + Q+
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVD---SDAADTASRPGTSTAALLAHLQR 225
Query: 389 KTTSVSLT-IGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKEL 447
+ ++ +S P TG T
Sbjct: 226 RREAMRAEGAPASPPSTGTRTC-------------------------------------- 247
Query: 448 QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLV 507
V EG+ L C V G P + W + G + + + + + +E L
Sbjct: 248 ---TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYE-------DAQENFVLK 297
Query: 508 IAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
I D G++TC+A N G S+ +VV
Sbjct: 298 ILFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 67.4 bits (163), Expect = 7e-11
Identities = 74/280 (26%), Positives = 117/280 (41%), Gaps = 34/280 (12%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
++ LR + E R LEC+V+ + +VRWF +EL P ++ +G LII++
Sbjct: 2293 VRPLRDKIAMEKHRGVLECQVS-RASAQVRWFKGSQELQPGPKYELVSDGL-YRKLIISD 2350
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDS-ESLAFKSRAGAMPQAQKKTTS 392
+D YTC A G TSA+ F+E S T + + A A + + S
Sbjct: 2351 VHAEDEDTYTCDA----GDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPS 2406
Query: 393 V---SLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAY----------- 438
V +G + + G + Q +V + S + P T
Sbjct: 2407 VRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSD 2466
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
P V T+ L+ E Q VVL C R AP VQW++ + + S F++ +
Sbjct: 2467 IPVVLTRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEG----- 2520
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ L I P DAG++ C A GSA S+ ++ V
Sbjct: 2521 ---QMAELRILRLMPADAGVYRCQA----GSAHSSTEVTV 2553
Score = 65.5 bits (158), Expect = 3e-10
Identities = 73/311 (23%), Positives = 116/311 (37%), Gaps = 62/311 (19%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHT 838
F +L + ++ E FTC+ +P + W K ++ H Q L +L
Sbjct: 2918 FTEELTNLQVEEKGTAVFTCKTE-HPAATVTWRKGLLELRASGKHQPSQEGL----TLRL 2972
Query: 839 TASTLD--DDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
T S L+ D YT Q R +L+VQ GR
Sbjct: 2973 TISALEKADSDTYTCDIGQAQSR----AQLLVQ-----GR-------------------- 3003
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956
R H ++ D+ VQEG C++S + W LD P+ +
Sbjct: 3004 -------------RVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANEL 3050
Query: 957 HKMLVRENGVHSLIIEPVTSRDAG-IYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK 1015
+++ + G H L + + +D+G IY RA A + KP VF +
Sbjct: 3051 NEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRAS---------AALRVTEKPSVFSRE 3101
Query: 1016 LQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGAT 1075
L + + +G + L C P + W K+ ++L S H+ + LLI GAT
Sbjct: 3102 LTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQ--LLITGAT 3158
Query: 1076 KEDAGWYTVSA 1086
+D+G Y A
Sbjct: 3159 LQDSGRYKCEA 3169
Score = 65.5 bits (158), Expect = 3e-10
Identities = 82/322 (25%), Positives = 121/322 (37%), Gaps = 63/322 (19%)
Query: 779 FEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG-TCSLH 837
F +L I EG +T C + P + W KDGK + + Q +G L
Sbjct: 3098 FSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSA---RCQLSHEGHRAQLL 3153
Query: 838 TTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDS 897
T +TL D G Y A +C+ ++ H R R
Sbjct: 3154 ITGATLQDSGRYKCEAGG-----ACSSSIV----------------RVHARPVR------ 3186
Query: 898 GDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAH 957
F +A DL V EG + C +S + P + W +RP +
Sbjct: 3187 ---------------FQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKY 3230
Query: 958 KMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQ 1017
L +E + L++ + +D+G Y+C G + S L V A P FI KL+
Sbjct: 3231 S-LRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTAL----PAQFIGKLR 3281
Query: 1018 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC-LLIQGATK 1076
N +G L C + P + W+K +E+L DR + QD G +C L I+G
Sbjct: 3282 NKEATEGATATLRCELSKAAP--VEWRKGSETL-RDGDRYCLRQD--GAMCELQIRGLAM 3336
Query: 1077 EDAGWYTVSAKNEAGIVSCTAR 1098
DA Y+ E S T R
Sbjct: 3337 VDAAEYSCVCGEERTSASLTIR 3358
Score = 63.2 bits (152), Expect = 1e-09
Identities = 76/352 (21%), Positives = 125/352 (35%), Gaps = 81/352 (23%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F E G + LEC V R RW +G EL + I G +L+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 331 IAEAFEDDTGRYT--------------CLATNPSGSDTTSA------------------- 357
I D G YT C+ + S S+ S+
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDAFRRAARRLHRL 5017
Query: 358 ------------EVFI---EGASSTDSDSESLAFKS-------RAGAMPQAQKKTT---- 391
E+F+ EG + + ++ ++ R A+ +A++ T
Sbjct: 5018 FRTKSPAEVSDEELFLSADEGPAEPEEPADWQTYREDEHFICIRFEALTEARQAVTRFQE 5077
Query: 392 -------SVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFT 444
V + + P+ V + + PV S L T+ PVF
Sbjct: 5078 MFATLGIGVEIKLVEQGPRR-VEMCISKETPAPVVPPEPLPSLL-------TSDAAPVFL 5129
Query: 445 KELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEIC 504
ELQN V +G V +C V G P V+WF+ G +++ + I + +
Sbjct: 5130 TELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGH------- 5182
Query: 505 TLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNN 556
L+I P D G++ C A N G +++ A+L V +T+ + ES++
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSS 5234
Score = 62.8 bits (151), Expect = 2e-09
Identities = 60/276 (21%), Positives = 102/276 (36%), Gaps = 75/276 (27%)
Query: 271 PRFIQKLRSQEVAEGSRVY-LECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
P+ +++LR +VA G+R+ + +V G P PR+ WF +G+ L + I++ + LHTL
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRM-TDKKILHTL 5318
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKK 389
I +D+G+Y +N G+ +SA + + G
Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD------------------------ 5354
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQN 449
+P P VH PP +
Sbjct: 5355 ----------------------EPEEKPASDVHE-------------QLVPPRMLERFTP 5379
Query: 450 TAVAEGQVVVLECRVRGAPPLQVQWFRQGSEI------QDSPDFRILQKKPRSTAEPEEI 503
V +G + +V G P V W R+ +E D+P + + A +
Sbjct: 5380 KKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV--------ASSAQQ 5431
Query: 504 CTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT 539
+LV+ + + G +TC A N G A +A L V+
Sbjct: 5432 HSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVS 5467
Score = 62.0 bits (149), Expect = 3e-09
Identities = 167/845 (19%), Positives = 288/845 (34%), Gaps = 155/845 (18%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
RFI+ +++QE EG+ L+C + N V W + L + + +G I
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIR 3596
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGA--SSTDSDSESLAFKSRAGAMPQAQKK 389
A D TG Y+C+ G + TSA + + T+ A + + K
Sbjct: 3597 GLAMAD-TGEYSCVC----GQERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSK 3651
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQP-----LSVPVQQVHSPTSYLCRPDGTTTAYF----- 439
V G + + G ++ Q L + YLC T+
Sbjct: 3652 MAPVEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRA 3711
Query: 440 -PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
P F + L+N EG L C + A P V+W + ++D + Q R
Sbjct: 3712 MPSKFIEGLRNEEATEGDTATLWCELSKAAP--VEWRKGHETLRDGDRHSLRQDGSR--- 3766
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDH 558
C L I DAG ++C + SAT T + + + E+ + E
Sbjct: 3767 -----CELQIRGLAVVDAGEYSCVCGQERTSATLTVR-ALPARFIEDVKNQEAREGATAV 3820
Query: 559 FQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPS-R 617
Q EL+ P E ++ + G R +L+ E + +G+ +
Sbjct: 3821 LQ-------------CELSKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADT 3867
Query: 618 GVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIASDEEIQGTK 677
G + G+ ++ +L A P P+ +P + TA + E+
Sbjct: 3868 GEYSCVCGQERTSATLTVRA--------PQPVFREPLQSLQAEEGSTATLQC--ELSEPT 3917
Query: 678 DAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKV 737
V+ + G +L R RL G + V +Q+ + E EY
Sbjct: 3918 ATVVW-------------SKGGLQLQANGRREPRLQGCTAELV--LQDLQREDTG-EYTC 3961
Query: 738 SSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFT 797
+ Q + + + +PV F +L+H ++ EG
Sbjct: 3962 TCGSQATSATLT--VTAAPVR--------------------FLRELQHQEVDEGGTAHLC 3999
Query: 798 CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS-LHTTASTLDDDGNYTIMAANP 856
C ++ + W K Q+ P + + +Q DG + L +D G+YT +
Sbjct: 4000 CELS-RAGASVEWRKGSLQLFPCAKYQMVQ---DGAAAELLVRGVEQEDAGDYTCDTGHT 4055
Query: 857 QGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQA 916
Q S + R V RP+ ++R E E
Sbjct: 4056 QSMASLSVR---------------------VPRPKFKTRLQSLEQET------------- 4081
Query: 917 PGDLTVQEGKLCRMDCKVSGLPTPDL-SWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
G + R+ C++S + + W +G + ++M + L+I +
Sbjct: 4082 --------GDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMR-SQGATRELLIHQLE 4132
Query: 976 SRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK-LQNTGVADGYPVRLECRVL 1034
++D G Y C+ GQ + A+ +P V I + L + V V C V
Sbjct: 4133 AKDTGEYACVT---GGQKT------AASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVS 4183
Query: 1035 GVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI-CLLIQGATKEDAGWYTVSAKNEAGIV 1093
+ W + L ++ V+ G I L ++G T EDAG + N A
Sbjct: 4184 RAGATGVQWCL--QGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSA 4241
Query: 1094 SCTAR 1098
T R
Sbjct: 4242 QLTVR 4246
Score = 61.2 bits (147), Expect = 5e-09
Identities = 72/293 (24%), Positives = 115/293 (39%), Gaps = 39/293 (13%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRV-RWFCEGKELHNTPDIQIHCEGGDLHTL 329
P+F +L+S E G L C+++ + V +W EG ELH P ++ +G L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGAT-REL 4126
Query: 330 IIAEAFEDDTGRYTCLATNPSGS--------DTTSAEVFIEGASSTDSDSESLAFKSRAG 381
+I + DTG Y C+ + + T ++ + D D E SRAG
Sbjct: 4127 LIHQLEAKDTGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAG 4186
Query: 382 A---------MPQAQKKTTSVSLTIGS--SSPKTGVTTAVIQPLSVPVQQVHSPTSYLCR 430
A +P + T V++ G + GVT +S + S R
Sbjct: 4187 ATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVR 4246
Query: 431 PDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
T + LQ+ ++EGQ +CR+ A + +W G +Q + I
Sbjct: 4247 APEVT-------ILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDI- 4298
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANT 543
T E + L + + EDAG + G+ +S AQL VT+ NT
Sbjct: 4299 ------TVEQGTLHLLTLHKVTLEDAGTVSFHV----GTCSSEAQLKVTAKNT 4341
Score = 59.7 bits (143), Expect = 1e-08
Identities = 174/857 (20%), Positives = 305/857 (35%), Gaps = 155/857 (18%)
Query: 275 QKLRSQEVAE-GSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
Q + ++ AE G+ L C V P V W+ +GK+L ++ +++ + G L++ +
Sbjct: 1170 QSVHNEVQAEAGTTAMLSCEVA-QPQTEVTWYKDGKKLSSSSKVRMEVK-GCTRRLVVQQ 1227
Query: 334 AFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESL--AFKSRAGA-------MP 384
+ D G Y+C A G S ++ I + + + + ++ AGA +
Sbjct: 1228 VGKADAGEYSCEA----GGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVA 1283
Query: 385 QAQKKTT--SVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF--- 439
QAQ + T + SSS ++ L V Y C G ++
Sbjct: 1284 QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEAGGQRLSFHLDV 1343
Query: 440 ---PPVFTKEL---QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKK 493
VF KE + G + L C V A +V W++ G ++ S R+
Sbjct: 1344 SEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQA-QTEVTWYKDGKKLSSSSKVRM---- 1398
Query: 494 PRSTAEPEEI-CT--LVIAETFPEDAGIFTCSARNDYGS-ATSTAQLVVTSANTENCSYE 549
E + CT LV+ + D G ++C A S + A+ V A + E
Sbjct: 1399 -------EAVGCTRRLVVQQACQADTGEYSCEAGGQRLSFSLDVAEPKVVFAKEQPVHRE 1451
Query: 550 SMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERE 609
++ T S E+A + + + +L S + ++M+ R
Sbjct: 1452 VQAQAGAS------------TTLSCEVAQAQTEVMWYKDGKKLSFS-SKVRMEAVGCTRR 1498
Query: 610 TNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKASRTARIAS 669
+ V G + +A S + LS +A+PK F K+ + + +
Sbjct: 1499 LVVQQAGQAVAGEYSCEAGSQR--------LSFHLH----VAEPKAVFAKEQPASREVQA 1546
Query: 670 DEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEE 729
+ T + + ++ + +D +L+ ++ +G V +QE +
Sbjct: 1547 EAGTSATLSCEVAQAQTEVTWYKD-----GKKLSSSSKVRMEAVGCTRRLV--VQEAGQA 1599
Query: 730 TANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIF 789
A EY + +QRL + V + ++ + +V E G +
Sbjct: 1600 DAG-EYSCKAGDQRL--SFHLHVAEPKVVFAKEQPAHREVQAEAGAS------------- 1643
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
T +C VA + ++ W+KDGK++S S + A
Sbjct: 1644 ----ATLSCEVA-QAQTEVTWYKDGKKLSSSS-------------KVRVEA--------- 1676
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEP-IQERF 908
+ CT RL+VQ Q S R R E EP I ER
Sbjct: 1677 ----------VGCTRRLVVQQAGQADAGEYSCEAGGQ----RLSFRLHVAELEPQISERP 1722
Query: 909 FRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHS 968
R L V+E + + ++ ++W DG +R H+ + H+
Sbjct: 1723 CRRE------PLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHE-TASQGDTHT 1775
Query: 969 LIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVR 1028
L + D+ IY+C GQ+ VAAK F L+ G V
Sbjct: 1776 LTVHGAQVLDSAIYSC-RVGAEGQDFPVQVEEVAAK-------FCRLLEPVCGELGGTVT 1827
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
L C L ++ W+ N L R M + L + G EDAG Y +++
Sbjct: 1828 LACE-LSPACAEVVWRCGNTQL-RVGKRFQMVAEG-PVRSLTVLGLRAEDAGEYVCESRD 1884
Query: 1089 EAGIVSCTARLDVYISR 1105
+ +A+L V + R
Sbjct: 1885 D----HTSAQLTVSVPR 1897
Score = 58.9 bits (141), Expect = 3e-08
Identities = 85/377 (22%), Positives = 128/377 (33%), Gaps = 94/377 (24%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGT--- 833
P F K++ EG FTC + G P P+I W+KDG ++ + T+ G
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 834 --------------CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVN------- 872
C L + I + Q + C +V AV
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERA 6227
Query: 873 --------QRGRSPRSPS--------------GHPHVRRPRSRSRDSGDENEP-IQERFF 909
+R P++P G P ++ S+ +G P + R
Sbjct: 6228 DQEVTSVLKRLLGPKAPGPSTGDLTGPGPCPRGAPALQETGSQPPVTGTSEAPAVPPRVP 6287
Query: 910 RPHFLQAPGD-----LTVQEGKL-CRMDCKV-SGLPTPDLSWQLDGKPVRPDSAHKMLVR 962
+P + P QE + RM+ G T +L W
Sbjct: 6288 QPLLHEGPEQEPEAIARAQEWTVPIRMEGAAWPGAGTGELLWD----------------- 6330
Query: 963 ENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVA 1022
VHS ++ T R Y I T+ A +PP +++
Sbjct: 6331 ---VHSHVVRETTQRTY-TYQAIDTHTA-----------------RPPSMQVTIEDVQAQ 6369
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
G + E + G P P + W K++ L ST R+S Q+ Y +L A+K DAG Y
Sbjct: 6370 TGGTAQFEAIIEGDPQPSVTWYKDSVQLVDST-RLSQQQEGTTYSLVLRHVASK-DAGVY 6427
Query: 1083 TVSAKNEAGIVSCTARL 1099
T A+N G V C A L
Sbjct: 6428 TCLAQNTGGQVLCKAEL 6444
Score = 57.4 bits (137), Expect = 7e-08
Identities = 33/112 (29%), Positives = 54/112 (48%), Gaps = 6/112 (5%)
Query: 429 CRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFR 488
C G PP F +++ + EG+ C + GAP Q++W++ G+ + F+
Sbjct: 6096 CSTLGKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQ 6155
Query: 489 ILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
L +PRS + LVI ED G++ C N GSA ++A+L + S
Sbjct: 6156 TL-SEPRS-----GLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201
Score = 57.0 bits (136), Expect = 1e-07
Identities = 184/886 (20%), Positives = 312/886 (35%), Gaps = 159/886 (17%)
Query: 281 EVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
+ G EC T V W+ +G EL ++ + + + G H L+ A D G
Sbjct: 808 DAVAGGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEG 866
Query: 341 RYTCLATNPSGSDTTSAEVFI---------EGASSTDSDSESLAFKSRAGAMPQAQKKTT 391
Y+C G D+ + + E + +E+ A + + + QAQ + T
Sbjct: 867 TYSCRV----GEDSVDFRLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVT 922
Query: 392 --SVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF------PPVF 443
+ SSS T + L V Y C G ++ VF
Sbjct: 923 WYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVF 982
Query: 444 TKEL---QNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
K+ G L C V A +V W++ G ++ S + K R
Sbjct: 983 AKDQVAHSEVQAEAGASATLSCEVAQA-QTEVMWYKDGKKLSSSLKVHVEAKGCRR---- 1037
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGS----ATSTAQLVVTSANTENCSYESMGES-- 554
LV+ + DAG ++C AR S T + + N G S
Sbjct: 1038 ----RLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAM 1093
Query: 555 -NNDHFQHFPPPPPILETSSLELASKKPSEIQQVNN----PELGLSRA--------ALQM 601
+ + Q + L +SK E++ P+ G + A ++
Sbjct: 1094 LSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRV 1153
Query: 602 QFNAAERETNGVH-PSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKK 660
F+ E GV + V+ + +A T A+L +P + K G KK
Sbjct: 1154 SFHLHITEPKGVFAKEQSVHNEVQAEAG------TTAMLSCEVAQPQTEVTWYKDG--KK 1205
Query: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMAR-RLLGADSAT 719
S ++++ E++G ++ K E G R++++ + + + A
Sbjct: 1206 LSSSSKVRM--EVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQL 1263
Query: 720 VFNIQEPEE--------ETANQEYKVSSCE--QRLISEIEYRLE-----RSPVDESGDEV 764
V N E E A + +V+ + ++L S + R+E R V + +
Sbjct: 1264 VHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQA 1323
Query: 765 QYGDVPVENG-------------MAPFFEMKLKHYKI--FEGMPVTFTCRVAGNPKPKIY 809
G+ E G A F + +L H K+ G T +C VA + ++
Sbjct: 1324 DAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVA-QAQTEVT 1382
Query: 810 WFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ 869
W+KDGK++S S M A + CT RL+VQ
Sbjct: 1383 WYKDGKKLSSSSK---------------------------VRMEA-----VGCTRRLVVQ 1410
Query: 870 AVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCR 929
Q + +G R S D EP + F + + ++ Q G
Sbjct: 1411 QACQ------ADTGEYSCEAGGQRLSFSLDVAEP-KVVFAKEQPVHR--EVQAQAGASTT 1461
Query: 930 MDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNR 989
+ C+V+ T ++ W DGK + S +M L+++ AG Y+C
Sbjct: 1462 LSCEVAQAQT-EVMWYKDGKKLSFSSKVRM-EAVGCTRRLVVQQAGQAVAGEYSC----E 1515
Query: 990 AGQNSFSLELVVAAKEAHKPPVFIEK---LQNTGVADGYPVRLECRVLGVPPPQIFWKKE 1046
AG S L VA +A VF ++ + G L C V ++ W K+
Sbjct: 1516 AGSQRLSFHLHVAEPKA----VFAKEQPASREVQAEAGTSATLSCEV-AQAQTEVTWYKD 1570
Query: 1047 NESLTHSTDRVSMHQDNHGYIC---LLIQGATKEDAGWYTVSAKNE 1089
+ L+ S+ +V M C L++Q A + DAG Y+ A ++
Sbjct: 1571 GKKLS-SSSKVRMEAVG----CTRRLVVQEAGQADAGEYSCKAGDQ 1611
Score = 54.3 bits (129), Expect = 6e-07
Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 5/119 (4%)
Query: 884 HPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAP-GDLTVQEGKLCRMDCKVSGLPTPDL 942
H HV R ++ + + I RP +Q D+ Q G + + + G P P +
Sbjct: 6332 HSHVVRETTQRTYT---YQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSV 6388
Query: 943 SWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
+W D + DS +E +SL++ V S+DAG+YTC+A N GQ EL+V
Sbjct: 6389 TWYKDSVQL-VDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 6446
Score = 54.3 bits (129), Expect = 6e-07
Identities = 32/96 (33%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P F +EL + V GQ V L C+V P Q W + G+ ++ S R+L +A
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSS--RVL-----ISATL 7515
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQL 536
+ L I ED G++TCS N G+ T+T L
Sbjct: 7516 KNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551
Score = 53.9 bits (128), Expect = 8e-07
Identities = 65/288 (22%), Positives = 108/288 (37%), Gaps = 30/288 (10%)
Query: 263 SALHFPAAP-RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC 321
+AL AP F +KL Q V E S V LE +T P P +RW L +++IH
Sbjct: 1979 AALRVREAPVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHA 2037
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIE--------GASSTDSDSES 373
EG H L++ D G + C + D T A++ +E G + ++ +
Sbjct: 2038 EGA-RHRLVLHNVGFADRGFFGC----ETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQG 2092
Query: 374 LAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDG 433
A + T L + L++ + + + +G
Sbjct: 2093 TATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVFKAEG 2152
Query: 434 TTTA------YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
T+ P F++ LQ+ E + V LEC + P + V+W + G E++
Sbjct: 2153 VHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAG--- 2208
Query: 488 RILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535
K + A +L I D G++ C A + SA+ Q
Sbjct: 2209 -----KTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASVKVQ 2251
Score = 52.8 bits (125), Expect = 2e-06
Identities = 41/149 (27%), Positives = 70/149 (46%), Gaps = 12/149 (8%)
Query: 941 DLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 1000
++ W L+G P+ DS H+ + + H+L+++ + DAGI A++ S LE+
Sbjct: 2587 EVEWSLNGMPLYNDSFHE-ISHKGRRHTLVLKSIQRADAGIVR--ASSLKVSTSARLEVR 2643
Query: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
V KP VF++ L + + + L+C V P + W+K+ L S +H
Sbjct: 2644 V------KPVVFLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLH 2696
Query: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
G L++ + EDAG YT +E
Sbjct: 2697 --TAGTRGLVVHDVSPEDAGLYTCHVGSE 2723
Score = 52.8 bits (125), Expect = 2e-06
Identities = 27/108 (25%), Positives = 48/108 (44%), Gaps = 7/108 (6%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL------HNTPDIQIHCEGG 324
PR +++ ++V +GS + +V G P P V W E E +TP +
Sbjct: 5371 PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV-ASSA 5429
Query: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372
H+L++ + G YTC+A+N +G SA + + G + +
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEK 5477
Score = 52.4 bits (124), Expect = 2e-06
Identities = 72/284 (25%), Positives = 110/284 (38%), Gaps = 33/284 (11%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F + L+S + EGS L+C ++ PT V W G +L + +G L+
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCELS-EPTATVVWSKGGLQLQANGRREPRLQGCTAE-LV 3947
Query: 331 IAEAFEDDTGRYTCLATNPSGSDT---TSAEV-FIEGASSTDSDSESLAF----KSRAGA 382
+ + +DTG YTC + + S T T+A V F+ + D A SRAGA
Sbjct: 3948 LQDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGA 4007
Query: 383 MPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT------TT 436
+ +K SL + + V L V + Y C T +
Sbjct: 4008 SVEWRKG----SLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSV 4063
Query: 437 AYFPPVFTKELQNTAVAEGQVVVLECRVRGAPP-LQVQWFRQGSEIQDSPDFRILQKKPR 495
P F LQ+ G + L C++ A VQW ++G E+ P + + R
Sbjct: 4064 RVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEM-----R 4118
Query: 496 STAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVT 539
S E L+I + +D G + C G + A L VT
Sbjct: 4119 SQGATRE---LLIHQLEAKDTGEYACVT----GGQKTAASLRVT 4155
Score = 52.0 bits (123), Expect = 3e-06
Identities = 63/277 (22%), Positives = 103/277 (37%), Gaps = 29/277 (10%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
RF + L+ EV EG L C ++ P V+W C G + D + G + L++
Sbjct: 3186 RFQEALKDLEVLEGGAATLRCVLSSVAAP-VKW-CYGNNVLRPGDKYSLRQEGAMLELVV 3243
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG--ASSTDSDSESLAFKSRAGAMPQAQKK 389
D+GRY+C G TTSA + + A A + + K
Sbjct: 3244 RNLRPQDSGRYSC----SFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELSK 3299
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVH-------SPTSYLCRPDGTTTAY---- 438
V GS + + G + Q ++ Q+ + S +C + T+ +
Sbjct: 3300 AAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRP 3359
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
P F L++ EG L C + A P V+W + ++D S
Sbjct: 3360 MPAHFIGRLRHQESIEGATATLRCELSKAAP--VEWRKGRESLRDG--------DRHSLR 3409
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535
+ +C L I DAG ++C + SAT T +
Sbjct: 3410 QDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVK 3446
Score = 52.0 bits (123), Expect = 3e-06
Identities = 48/189 (25%), Positives = 81/189 (42%), Gaps = 25/189 (13%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
D V + C+VS + W L G P++ + ++ VR+ +H+L ++ VT D
Sbjct: 4167 DAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPED 4226
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPP 1038
AG + G ++ S +L V A E +E LQ+ +++G +CR+
Sbjct: 4227 AG----TVSFHLGNHASSAQLTVRAPEV----TILEPLQDVQLSEGQDASFQCRLSRASG 4278
Query: 1039 PQIFWK------KENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGI 1092
+ W + NE + ++ ++H L + T EDAG TVS G
Sbjct: 4279 QEARWALGGVPLQANEMNDITVEQGTLH-------LLTLHKVTLEDAG--TVSF--HVGT 4327
Query: 1093 VSCTARLDV 1101
S A+L V
Sbjct: 4328 CSSEAQLKV 4336
Score = 52.0 bits (123), Expect = 3e-06
Identities = 42/172 (24%), Positives = 70/172 (40%), Gaps = 17/172 (9%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
Q AL P F ++L G V L CRVTG P P + W+ +GK + P I
Sbjct: 6003 QQRLALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPH-HI 6061
Query: 320 HCEGGDLHTLIIAEAFED-DTGRYTCLATNPSGSDTTSAEVFIE----------GASSTD 368
E D +I ++ D+G+Y C A + +G+ +T ++ ++ + +
Sbjct: 6062 LIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVNKVRASPFVE 6121
Query: 369 SDSESLAFKSRAGAMPQAQKKTTSVSLTIGS-----SSPKTGVTTAVIQPLS 415
+ PQ + LT G+ S P++G+ VI+ S
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAAS 6173
Score = 51.6 bits (122), Expect = 4e-06
Identities = 69/282 (24%), Positives = 108/282 (38%), Gaps = 32/282 (11%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
P FI +LR QE EG+ L C + + V W +G+E D + G +
Sbjct: 3359 PMPAHFIGRLRHQESIEGATATLRCEL--SKAAPVEW-RKGRESLRDGDRHSLRQDGAVC 3415
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEG--ASSTDSDSESLAFKSRAGAMPQ 385
L I D G Y+C+ G + TSA + ++ A T+ A + +
Sbjct: 3416 ELQICGLAVADAGEYSCVC----GEERTSATLTVKALPAKFTEGLRNEEAVEGATAMLWC 3471
Query: 386 AQKKTTSVSLTIGSSSPKTGVTTAVIQ-----PLSVPVQQVHSPTSYLC-----RPDGT- 434
K V G + + G + Q L + + YLC R T
Sbjct: 3472 ELSKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATL 3531
Query: 435 TTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE-IQDSPDFRILQKK 493
T P F ++++N EG VL+C + A P V+W R+GSE ++D + + Q
Sbjct: 3532 TIRALPARFIEDVKNQEAREGATAVLQCELNSAAP--VEW-RKGSETLRDGDRYSLRQDG 3588
Query: 494 PRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535
+ C L I D G ++C + SA T +
Sbjct: 3589 TK--------CELQIRGLAMADTGEYSCVCGQERTSAMLTVR 3622
Score = 51.6 bits (122), Expect = 4e-06
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P+F+ +T G + LEC V ++ +W + G E+ D I Q
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG------- 4950
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQ 560
+ C+L+I DAG +TC N +G T +A +VV+ + +E + S G +D F+
Sbjct: 4951 DGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESE--AESSSGGELDDAFR 5008
Score = 50.8 bits (120), Expect = 7e-06
Identities = 48/190 (25%), Positives = 81/190 (42%), Gaps = 13/190 (6%)
Query: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
+P F + L +EG + C++S PT + W G ++ + + + + L
Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCELSE-PTATVVWSKGGLQLQANGRREPRL-QGCTAEL 3946
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
+++ + D G YTC G + S L V A P F+ +LQ+ V +G L
Sbjct: 3947 VLQDLQREDTGEYTCTC----GSQATSATLTVTAA----PVRFLRELQHQEVDEGGTAHL 3998
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
C L + W+K + L + M QD LL++G +EDAG YT +
Sbjct: 3999 CCE-LSRAGASVEWRKGSLQLFPCA-KYQMVQDGAAAE-LLVRGVEQEDAGDYTCDTGHT 4055
Query: 1090 AGIVSCTARL 1099
+ S + R+
Sbjct: 4056 QSMASLSVRV 4065
Score = 50.1 bits (118), Expect = 1e-05
Identities = 26/87 (29%), Positives = 42/87 (48%)
Query: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
AP F+++L + V G V L C+V+ P + W +G L ++ + I + L
Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 7521
Query: 330 IIAEAFEDDTGRYTCLATNPSGSDTTS 356
I +D G YTC +N G+ TT+
Sbjct: 7522 TILVVVAEDLGVYTCSVSNALGTVTTT 7548
Score = 49.7 bits (117), Expect = 2e-05
Identities = 74/326 (22%), Positives = 123/326 (37%), Gaps = 65/326 (19%)
Query: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
M F +L+H + EG T C ++ + W K G++ D +++++D C
Sbjct: 3360 MPAHFIGRLRHQESIEGATATLRCELS--KAAPVEWRK-GRESLRDGDRHSLRQD-GAVC 3415
Query: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRS 894
L + D G Y+ + + R S T L V+A+ +
Sbjct: 3416 ELQICGLAVADAGEYSCVCG--EERTSAT--LTVKALPAK-------------------- 3451
Query: 895 RDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
F + + EG + C++S + + W+ + +R
Sbjct: 3452 ------------------FTEGLRNEEAVEGATAMLWCELSKVAP--VEWRKGPENLR-- 3489
Query: 955 SAHKMLVRENGVH-SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFI 1013
+ ++R+ G L I + DAG Y C+ GQ S L + A A FI
Sbjct: 3490 DGDRYILRQEGTRCELQICGLAMADAGEYLCVC----GQERTSATLTIRALPAR----FI 3541
Query: 1014 EKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC-LLIQ 1072
E ++N +G L+C + P + W+K +E+L DR S+ QD G C L I+
Sbjct: 3542 EDVKNQEAREGATAVLQCELNSAAP--VEWRKGSETL-RDGDRYSLRQD--GTKCELQIR 3596
Query: 1073 GATKEDAGWYTVSAKNEAGIVSCTAR 1098
G D G Y+ E T R
Sbjct: 3597 GLAMADTGEYSCVCGQERTSAMLTVR 3622
Score = 49.7 bits (117), Expect = 2e-05
Identities = 67/277 (24%), Positives = 107/277 (38%), Gaps = 30/277 (10%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+F + LR++E EG+ L C ++ V W +G E D I + G L I
Sbjct: 3451 KFTEGLRNEEAVEGATAMLWCELS--KVAPVEWR-KGPENLRDGDRYILRQEGTRCELQI 3507
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD-SDSESLAFKSRAGAMPQAQKKT 390
D G Y C+ G + TSA + I + D ++ + A A+ Q + +
Sbjct: 3508 CGLAMADAGEYLCVC----GQERTSATLTIRALPARFIEDVKNQEAREGATAVLQCELNS 3563
Query: 391 TS-VSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT-------SYLCRPDGT----TTAY 438
+ V GS + + G ++ Q + Q+ S +C + T T
Sbjct: 3564 AAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRA 3623
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
P FT+ L+N EG VL C + P V+W++ ++D + Q R
Sbjct: 3624 LPIKFTEGLRNEEATEGATAVLRCELSKMAP--VEWWKGHETLRDGDRHSLRQDGAR--- 3678
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535
C L I EDAG + C + SA T +
Sbjct: 3679 -----CELQIRGLVAEDAGEYLCMCGKERTSAMLTVR 3710
Score = 49.7 bits (117), Expect = 2e-05
Identities = 30/96 (31%), Positives = 44/96 (45%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P F GD Q G R++C V+ W DG + H + +G SL+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEA 1006
I + DAG YTC +N+ GQ + S +VV+ E+
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSES 4993
Score = 49.3 bits (116), Expect = 2e-05
Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 1008 KPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYI 1067
+PP F E+L + G V+L CRV G P P I W K+ +++ + + +D G
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHI-LIEDPDGSC 6070
Query: 1068 CLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYI 1103
L++ T D+G Y A + AG S ++ V +
Sbjct: 6071 ALILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV 6106
Score = 48.9 bits (115), Expect = 3e-05
Identities = 60/280 (21%), Positives = 106/280 (37%), Gaps = 29/280 (10%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAE 333
I+ L +V EGS CR++ V WF + LH +I + G H L + +
Sbjct: 3008 IEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQ 3067
Query: 334 AFEDDTGRYTCLATNPSGSD----TTSAEVF---IEGASSTDSDSESLAFKSRAGAMPQA 386
D+G A + S T VF + A+ T+ + +L ++ +P
Sbjct: 3068 LALKDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVC 3127
Query: 387 QKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYF------P 440
K T+ S+ L + + Y C G ++ P
Sbjct: 3128 WTKD---GKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARP 3184
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
F + L++ V EG L C V + V+W + ++ + + Q+
Sbjct: 3185 VRFQEALKDLEVLEGGAATLRC-VLSSVAAPVKWCYGNNVLRPGDKYSLRQE-------- 3235
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
+ LV+ P+D+G ++CS +G T++A L VT+
Sbjct: 3236 GAMLELVVRNLRPQDSGRYSCS----FGDQTTSATLTVTA 3271
Score = 48.5 bits (114), Expect = 3e-05
Identities = 32/111 (28%), Positives = 48/111 (43%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
P FL+ D TV G+ + C+VS P +W DG P+ S + L
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522
Query: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGV 1021
I V + D G+YTC +N G + + L A + + P I ++ GV
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGV 7573
Score = 47.8 bits (112), Expect = 6e-05
Identities = 66/275 (24%), Positives = 104/275 (37%), Gaps = 30/275 (10%)
Query: 272 RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLII 331
+FI KLR++E EG+ L C + + V W +G E D + G + L I
Sbjct: 3275 QFIGKLRNKEATEGATATLRCEL--SKAAPVEW-RKGSETLRDGDRYCLRQDGAMCELQI 3331
Query: 332 AEAFEDDTGRYTCLATNPSGSDTTSAEVFIE--GASSTDSDSESLAFKSRAGAMPQAQKK 389
D Y+C+ G + TSA + I A + + + K
Sbjct: 3332 RGLAMVDAAEYSCVC----GEERTSASLTIRPMPAHFIGRLRHQESIEGATATLRCELSK 3387
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQV-------HSPTSYLCRPDGT----TTAY 438
V G S + G ++ Q +V Q+ S +C + T T
Sbjct: 3388 AAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKA 3447
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
P FT+ L+N EG +L C + P V+W + ++D + + Q+ R
Sbjct: 3448 LPAKFTEGLRNEEAVEGATAMLWCELSKVAP--VEWRKGPENLRDGDRYILRQEGTRCEL 3505
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATST 533
+IC L +A DAG + C + SAT T
Sbjct: 3506 ---QICGLAMA-----DAGEYLCVCGQERTSATLT 3532
Score = 47.8 bits (112), Expect = 6e-05
Identities = 72/291 (24%), Positives = 111/291 (38%), Gaps = 32/291 (10%)
Query: 263 SALHFPAAP-RFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC 321
+ L AAP RF+++L+ QEV EG +L C ++ V W +L Q+
Sbjct: 3970 ATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELS-RAGASVEWRKGSLQLFPCAKYQM-V 4027
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEV----FIEGASSTDSDSESLA-- 375
+ G L++ ++D G YTC + + S V F S + ++ +A
Sbjct: 4028 QDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARL 4087
Query: 376 ----FKSRAGAMPQAQKKTTSVSLTIGSSSPKTGV-TTAVIQPLSVPVQQVHSPTSYLCR 430
+ +GA+ Q K+ V L G PK + + + L + + Y C
Sbjct: 4088 CCQLSDAESGAVVQWLKE--GVELHAG---PKYEMRSQGATRELLIHQLEAKDTGEYACV 4142
Query: 431 PDGTTTAYFPPVFTKE------LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDS 484
G TA V E L + V + V C V A VQW QG +Q +
Sbjct: 4143 TGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSN 4202
Query: 485 PDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQ 535
+ + R I TL + PEDAG + N SA T +
Sbjct: 4203 EVTEVAVRDGR-------IHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVR 4246
Score = 47.8 bits (112), Expect = 6e-05
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 2/109 (1%)
Query: 266 HFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGD 325
H P + + G E + G+P P V W+ + +L ++ + EG
Sbjct: 6352 HTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEG-T 6410
Query: 326 LHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGA-SSTDSDSES 373
++L++ D G YTCLA N G AE+ + G + DS+ +S
Sbjct: 6411 TYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQS 6459
Score = 46.6 bits (109), Expect = 1e-04
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 4/111 (3%)
Query: 989 RAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENE 1048
+ G SF L K + P F+ +L + V G V L C+V P Q W K+
Sbjct: 7445 KPGLASFRLS---GLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGA 7501
Query: 1049 SLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARL 1099
L S+ RV + + L I ED G YT S N G V+ T L
Sbjct: 7502 PL-ESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551
Score = 45.4 bits (106), Expect = 3e-04
Identities = 33/109 (30%), Positives = 43/109 (39%), Gaps = 10/109 (9%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEI--QDSPDFRILQKKPRSTA 498
P F + V EG CRV G+P V W + G + D P R+
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRV--------E 161
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCS 547
E E L I P D G + A N G+A++ A LVV S + S
Sbjct: 162 ELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTAS 210
Score = 45.1 bits (105), Expect = 4e-04
Identities = 47/187 (25%), Positives = 69/187 (36%), Gaps = 13/187 (6%)
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIE 972
FL+A DL+ +E + C+VS P + W+ DG + P + L G L++
Sbjct: 2649 FLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKYDFL-HTAGTRGLVVH 2706
Query: 973 PVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK-LQNTGVADGYPVRLEC 1031
V+ DAG+YTC E A H V I K L+ V +G EC
Sbjct: 2707 DVSPEDAGLYTC---------HVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFEC 2757
Query: 1032 RVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
+ S+ R + YI L+++ A DAG S +
Sbjct: 2758 VLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYI-LVVREAAPSDAGEVVFSVRGLTS 2816
Query: 1092 IVSCTAR 1098
S R
Sbjct: 2817 KASLIVR 2823
Score = 45.1 bits (105), Expect = 4e-04
Identities = 70/276 (25%), Positives = 105/276 (38%), Gaps = 32/276 (11%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F ++L + EG + L C + P V W +GK L + Q+ EG L+I
Sbjct: 3098 FSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQ-LLIT 3155
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTS 392
A D+GRY C A S D E L G + +S
Sbjct: 3156 GATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVL-----EGGAATLRCVLSS 3210
Query: 393 VSLTI----GSSSPKTGVTTAVIQP---LSVPVQQVHSPTS--YLCR-PDGTTTA----- 437
V+ + G++ + G ++ Q L + V+ + S Y C D TT+A
Sbjct: 3211 VAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQTTSATLTVT 3270
Query: 438 YFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
P F +L+N EG L C + A P V+W R+GSE D L+
Sbjct: 3271 ALPAQFIGKLRNKEATEGATATLRCELSKAAP--VEW-RKGSETLRDGDRYCLR------ 3321
Query: 498 AEPEEICTLVIAETFPEDAGIFTCSARNDYGSATST 533
+ +C L I DA ++C + SA+ T
Sbjct: 3322 -QDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLT 3356
Score = 44.7 bits (104), Expect = 5e-04
Identities = 55/248 (22%), Positives = 88/248 (35%), Gaps = 30/248 (12%)
Query: 278 RSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFED 337
R+ V EG L C VTG P P W +G+ + ++ + + L I +
Sbjct: 245 RTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQS 304
Query: 338 DTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTI 397
D G YTC A+N G +S V + ++ FK R + +K++ + +
Sbjct: 305 DRGLYTCTASNLVGQTYSSVLVVVR--------EPAVPFKKRLQDLEVREKESATFLCEV 356
Query: 398 GS---------------SSPKTGV-TTAVIQPLSVPVQQVHSPTSYLCR-PDGTTT---- 436
+S K G+ + L+V Y+C P+G+ T
Sbjct: 357 PQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAEL 416
Query: 437 AYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRS 496
A + K + TAV G + C P V W R E+ I + R
Sbjct: 417 AVQGNLLRKLPRKTAVRVGDTAMF-CVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRH 475
Query: 497 TAEPEEIC 504
T + C
Sbjct: 476 TLTISQCC 483
Score = 44.3 bits (103), Expect = 6e-04
Identities = 35/161 (21%), Positives = 66/161 (40%), Gaps = 9/161 (5%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
D+ + EG+ C++S + W L G P++ + + + V + +H L + VT D
Sbjct: 4258 DVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLED 4317
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPP 1038
AG + G S +L V AK + L+N +G EC++
Sbjct: 4318 AG----TVSFHVGTCSSEAQLKVTAKN-----TVVRGLENVEALEGGEALFECQLSQPEV 4368
Query: 1039 PQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDA 1079
W ++E + S + + +N LL++ +D+
Sbjct: 4369 AAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDS 4409
Score = 43.5 bits (101), Expect = 0.001
Identities = 50/218 (22%), Positives = 79/218 (36%), Gaps = 14/218 (6%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
PAA I+ L Q VA G V L C ++ TP V W + K + + + CEG +
Sbjct: 2826 PAA--IIKPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEG-TMA 2881
Query: 328 TLIIAEAFEDDTGRYTCLATNPSGSDT----TSAEVFIEGASSTDSDSESLAFKSRAGAM 383
L+I A D G YTC + + A F E ++ + + A +
Sbjct: 2882 MLVIRGASLKDAGEYTCEVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEH 2941
Query: 384 PQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPV- 442
P A L + +S + L++ + +Y C + V
Sbjct: 2942 PAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQ 3001
Query: 443 -----FTKELQNTAVAEGQVVVLECRVRGAPPLQVQWF 475
++L++ V EG CR+ A V WF
Sbjct: 3002 GRRVHIIEDLEDVDVQEGSSATFRCRISPANYEPVHWF 3039
Score = 43.1 bits (100), Expect = 0.001
Identities = 65/266 (24%), Positives = 99/266 (37%), Gaps = 59/266 (22%)
Query: 273 FIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIA 332
F + L+ E +V LEC ++ P VRW +G EL + I +G +L I
Sbjct: 2168 FSRPLQDVVTTEKEKVTLECELS-RPNVDVRWLKDGVELRAGKTMAIAAQGA-CRSLTIY 2225
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTS 392
D G Y C A + +SA V ++G + T LA AG + + S
Sbjct: 2226 RCEFADQGVYVCDAHDAQ----SSASVKVQGRTYTLIYRRVLA--EDAGEIQFVAENAES 2279
Query: 393 VSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAV 452
A ++ +PV L RP L++
Sbjct: 2280 ---------------RAQLRVKELPVT--------LVRP---------------LRDKIA 2301
Query: 453 AEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETF 512
E VLEC+V A QV+WF+ E+Q P + ++ L+I++
Sbjct: 2302 MEKHRGVLECQVSRASA-QVRWFKGSQELQPGPKYELVSDGLYR--------KLIISDVH 2352
Query: 513 PEDAGIFTCSARNDYGSATSTAQLVV 538
ED +TC D G ++AQ V
Sbjct: 2353 AEDEDTYTC----DAGDVKTSAQFFV 2374
Score = 42.4 bits (98), Expect = 0.002
Identities = 34/142 (23%), Positives = 61/142 (42%), Gaps = 9/142 (6%)
Query: 942 LSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
++W DG+ + P +++ G L++ V DAG+Y C+ +R G+ ++ L +
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASA-GRRVLLVRDVARDDAGLYECV--SRGGRIAYQLSVQG 793
Query: 1002 AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQ 1061
A+ HK G P + EC + W K+ L HS +R + +
Sbjct: 794 LARFLHKDMAG----SCVDAVAGGPAQFECET-SEAHVHVHWYKDGMELGHSGERF-LQE 847
Query: 1062 DNHGYICLLIQGATKEDAGWYT 1083
D L+ T++D G Y+
Sbjct: 848 DVGTRHRLVAATVTRQDEGTYS 869
Score = 42.4 bits (98), Expect = 0.002
Identities = 66/304 (21%), Positives = 111/304 (36%), Gaps = 42/304 (13%)
Query: 238 GARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGN 297
G C +Q L+ H + P+ A PA+ R + G+ L C V
Sbjct: 1510 GEYSCEAGSQRLSF-HLHVAEPKAVFAKEQPAS-------REVQAEAGTSATLSCEVAQA 1561
Query: 298 PTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSA 357
T V W+ +GK+L ++ +++ G L++ EA + D G Y+C A G S
Sbjct: 1562 QT-EVTWYKDGKKLSSSSKVRMEAVGCT-RRLVVQEAGQADAGEYSCKA----GDQRLSF 1615
Query: 358 EVFI---------EGASSTDSDSESLAFKSRAGAMPQAQKKTT--SVSLTIGSSSPKTGV 406
+ + E + + +E+ A + + + QAQ + T + SSS
Sbjct: 1616 HLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVE 1675
Query: 407 TTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT---------AVAEGQV 457
+ L V Y C G ++ V E Q + V E +
Sbjct: 1676 AVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEPQISERPCRREPLVVKEHED 1735
Query: 458 VVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAG 517
++L + V W + G EI+ S K TA + TL + D+
Sbjct: 1736 IILTATLATPSAATVTWLKDGVEIRRS--------KRHETASQGDTHTLTVHGAQVLDSA 1787
Query: 518 IFTC 521
I++C
Sbjct: 1788 IYSC 1791
Score = 41.2 bits (95), Expect = 0.005
Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Query: 776 APFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCS 835
AP F +L + G VT C+V+ P + W KDG + S I L
Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLE-SSSRVLISATLKNFQL 7520
Query: 836 LHTTASTLDDDGNYTIMAANPQGRISCTGRL 866
L +D G YT +N G ++ TG L
Sbjct: 7521 LTILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551
Score = 40.8 bits (94), Expect = 0.007
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
Query: 787 KIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ-----ISPKSDHYTIQRDLDGTCSLHTTAS 841
K+ +G +TF+ +V G P P ++W ++ + I P + YT+ SL
Sbjct: 5381 KVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH-SLVLLDV 5439
Query: 842 TLDDDGNYTIMAANPQGRISCTGRLMVQAV 871
G YT +A+N G+ C+ L V +
Sbjct: 5440 GRQHQGTYTCIASNAAGQALCSASLHVSGL 5469
Score = 39.7 bits (91), Expect = 0.016
Identities = 64/275 (23%), Positives = 104/275 (37%), Gaps = 33/275 (12%)
Query: 282 VAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGR 341
V E + L + V W +G E+ + + +G D HTL + A D+
Sbjct: 1730 VKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQG-DTHTLTVHGAQVLDSAI 1788
Query: 342 YTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTI---G 398
Y+C G++ V +E ++ G + A + + + + + G
Sbjct: 1789 YSCRV----GAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACAEVVWRCG 1844
Query: 399 SSSPKTG-----VTTAVIQPLSVPVQQVHSPTSYLC--RPDGTT---TAYFPPV--FTKE 446
++ + G V ++ L+V + Y+C R D T+ T P V F
Sbjct: 1845 NTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSG 1904
Query: 447 LQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTL 506
L EG +C V + + V WFR G+ +Q S F I Q +L
Sbjct: 1905 LSTVVAEEGGEATFQCVVSPSD-VAVVWFRDGALLQPSEKFAISQSGASH--------SL 1955
Query: 507 VIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSA 541
I++ EDAG T A A+S+A L V A
Sbjct: 1956 TISDLVLEDAGQITVEAE----GASSSAALRVREA 1986
Score = 39.7 bits (91), Expect = 0.016
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
P+F +T G +RLEC V + W K+ LT + Q G L
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHH-HIDQLGDGTCSL 4956
Query: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTA 1097
LI G + DAG YT N+ G V+ +A
Sbjct: 4957 LITGLDRADAGCYTCQVSNKFGQVTHSA 4984
Score = 38.5 bits (88), Expect = 0.036
Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 8/98 (8%)
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
P F + V+ G+ L C++ G P QV W + + FR+ A+
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRL--------AQD 61
Query: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++ L I + D+G + C ARN G A + L V
Sbjct: 62 GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 38.5 bits (88), Expect = 0.036
Identities = 26/82 (31%), Positives = 38/82 (46%), Gaps = 9/82 (10%)
Query: 440 PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAE 499
P VF K L + + E + L+C V P V W + G ++ S + L TA
Sbjct: 2646 PVVFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKYDFLH-----TAG 2699
Query: 500 PEEICTLVIAETFPEDAGIFTC 521
LV+ + PEDAG++TC
Sbjct: 2700 TRG---LVVHDVSPEDAGLYTC 2718
Score = 37.7 bits (86), Expect = 0.061
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 24/164 (14%)
Query: 944 WQLDGKPVRPDSAHKMLVRENGV-HSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVA 1002
W DG + S + L + G H L+ VT +D G Y+C R G++S L V+
Sbjct: 830 WYKDGMELG-HSGERFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRVS 884
Query: 1003 AKEA--HKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
+ K + KLQ G L C V ++ W K+ + L+ S+ +V M
Sbjct: 885 EPKVVFAKEQLARRKLQ---AEAGASATLSCEV-AQAQTEVTWYKDGKKLS-SSSKVCME 939
Query: 1061 QDNHGYIC---LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
C L++Q A + DAG Y+ EAG + LDV
Sbjct: 940 ATG----CTRRLVVQQAGQADAGEYSC----EAGGQRLSFHLDV 975
Score = 37.4 bits (85), Expect = 0.079
Identities = 44/167 (26%), Positives = 68/167 (40%), Gaps = 17/167 (10%)
Query: 919 DLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRD 978
D V G+ + C++S TP + W D K +R + + V E + L+I + +D
Sbjct: 2835 DQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDV-VCEGTMAMLVIRGASLKD 2892
Query: 979 AGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPP 1038
AG YTC A +++ SL + K F E+L N V + C+ P
Sbjct: 2893 AGEYTCEV--EASKSTASLHV------EEKANCFTEELTNLQVEEKGTAVFTCKT-EHPA 2943
Query: 1039 PQIFWKKENESLTHSTDRVSMHQDNHGYIC--LLIQGATKEDAGWYT 1083
+ W+K L S HQ + + L I K D+ YT
Sbjct: 2944 ATVTWRKGLLELRAS----GKHQPSQEGLTLRLTISALEKADSDTYT 2986
Score = 33.9 bits (76), Expect = 0.88
Identities = 35/158 (22%), Positives = 64/158 (40%), Gaps = 11/158 (6%)
Query: 941 DLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELV 1000
++ W+ +R +M V E V SL + + + DAG Y C + + S +L
Sbjct: 1838 EVVWRCGNTQLRVGKRFQM-VAEGPVRSLTVLGLRAEDAGEYVC----ESRDDHTSAQLT 1892
Query: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
V+ K F+ L +G +C V+ + W ++ +L +++ ++
Sbjct: 1893 VSVPRVVK---FMSGLSTVVAEEGGEATFQC-VVSPSDVAVVWFRDG-ALLQPSEKFAIS 1947
Query: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTAR 1098
Q + L I EDAG TV A+ + + R
Sbjct: 1948 QSGASH-SLTISDLVLEDAGQITVEAEGASSSAALRVR 1984
Score = 33.1 bits (74), Expect = 1.5
Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 5/91 (5%)
Query: 274 IQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQ-IHCEGGDLHTLIIA 332
++ L + E EG EC+++ W + + +H + + + + E G H L++
Sbjct: 4343 VRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLK 4402
Query: 333 EAFEDDTGRYTCLATNPSGSDTTSAEVFIEG 363
D+ R T LA G TSA + + G
Sbjct: 4403 NLRPQDSCRVTFLA----GDMVTSAFLTVRG 4429
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/78 (24%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 907 RFFRPHFLQAPGDLTVQEGKLCRMDCKVS-GLPTPDLSWQLDGKPVRPDSAHKMLVRENG 965
R +R L+ + V+ G C +S +P + SW ++G V+PD + + +
Sbjct: 4428 RGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGS 4487
Query: 966 VHSLIIEPVTSRDAGIYT 983
H+L++ AG T
Sbjct: 4488 HHALLLRSAQPHHAGEVT 4505
>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
sapiens]
Length = 1386
Score = 102 bits (255), Expect = 2e-21
Identities = 83/323 (25%), Positives = 135/323 (41%), Gaps = 59/323 (18%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA-----ST 842
+ G P T CR G P+P I W+K+G +++ + R L + +L
Sbjct: 75 VSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRA 134
Query: 843 LDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENE 902
D+G YT +A N G + N
Sbjct: 135 RPDEGVYTCVARNYLGA-------------------------------------AASRNA 157
Query: 903 PIQERFFRPHFLQAPGDLTVQEGKLCRMDC-KVSGLPTPDLSWQLDGKPVRPDSAHKMLV 961
++ R F Q+PG++ V G+ ++C G P P +SW+ DG ++ + ++ +
Sbjct: 158 SLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEG-RITI 216
Query: 962 RENGVHSLIIEPVTSRDAGIYTCIATNRAGQ-NSFSLELVVAAKEAHKPPVFIEKLQNTG 1020
R L++ DAG+Y C+A+N AG+ S + E++V + P F+ + N
Sbjct: 217 RGG---KLMMSHTLKSDAGMYVCVASNMAGERESAAAEVMVLER-----PSFLRRPVNQV 268
Query: 1021 VADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
V PV C V G PPP++ W+KE+ L T R + D+ L I + ED G
Sbjct: 269 VLADAPVTFLCEVKGDPPPRLRWRKEDGEL--PTGRYEIRSDH----SLWIGHVSAEDEG 322
Query: 1081 WYTVSAKNEAGIVSCTARLDVYI 1103
YT A+N G + L V++
Sbjct: 323 TYTCVAENSVGRAEASGSLSVHV 345
Score = 86.7 bits (213), Expect = 1e-16
Identities = 86/322 (26%), Positives = 125/322 (38%), Gaps = 58/322 (18%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P F + + + PVTF C V G+P P++ W K+ ++ + Y I+ D SL
Sbjct: 258 PSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELP--TGRYEIRSDH----SL 311
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
+ +D+G YT +A N GR +G L V HV
Sbjct: 312 WIGHVSAEDEGTYTCVAENSVGRAEASGSLSV-----------------HVP-------- 346
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVR--PD 954
P + P D G+ C+ G P P + WQ +G V P
Sbjct: 347 --------------PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPS 392
Query: 955 SA----HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQN-SFSLELVVAAKEAHKP 1009
+ + V G L I V DAG Y C A + AG + +L + A P
Sbjct: 393 QSLQPTGRFSVSPRG--QLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLP 450
Query: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
PV ++ N + G V L CRV G P P + WKK+ + L D + +G L
Sbjct: 451 PVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWL--QGDDLQFKTMANG--TL 506
Query: 1070 LIQGATKEDAGWYTVSAKNEAG 1091
I + D G+Y+ AK+ G
Sbjct: 507 YIANVQEMDMGFYSCVAKSSTG 528
Score = 77.4 bits (189), Expect = 7e-14
Identities = 59/195 (30%), Positives = 84/195 (43%), Gaps = 29/195 (14%)
Query: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDG---KPVRPD-SAHKMLVRENG- 965
P ++ P DL V G+ + C+ G P P++ W +G VR D AH++L+
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123
Query: 966 -----VHSLIIEPVTSRDAGIYTCIATN---RAGQNSFSLELVVAAKEAHKPPVFIEKLQ 1017
VH P D G+YTC+A N A + SLE+ V + + P
Sbjct: 124 FFPRIVHGRRARP----DEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSP------G 173
Query: 1018 NTGVADGYPVRLEC-RVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 1076
N VA G P LEC G P P + W+K+ L R+++ L++ K
Sbjct: 174 NVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGK-----LMMSHTLK 228
Query: 1077 EDAGWYTVSAKNEAG 1091
DAG Y A N AG
Sbjct: 229 SDAGMYVCVASNMAG 243
Score = 76.6 bits (187), Expect = 1e-13
Identities = 77/289 (26%), Positives = 114/289 (39%), Gaps = 43/289 (14%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P F+++ +Q V + V C V G+P PR+RW E EL T +I + H+L
Sbjct: 258 PSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL-PTGRYEIRSD----HSLW 312
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFI--------EGASSTDSDSESLAFKSRAGA 382
I +D G YTC+A N G S + + + + ES+AF+
Sbjct: 313 IGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKG 372
Query: 383 MPQA----QKKTTSVSLTIGSSSPKTG-VTTAVIQPLSVPVQQVHSPTSYLCRP------ 431
P QK+ + V L S TG + + L++ Q Y+C+
Sbjct: 373 NPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGS 432
Query: 432 ---------DGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQ 482
G + PPV + N + G V L CRV G P V+W + G +Q
Sbjct: 433 ILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQ 492
Query: 483 DSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSAT 531
LQ K + TL IA D G ++C A++ G AT
Sbjct: 493 GDD----LQFKTMANG------TLYIANVQEMDMGFYSCVAKSSTGEAT 531
Score = 67.4 bits (163), Expect = 7e-11
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 42/288 (14%)
Query: 282 VAEGSRVYLEC-RVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
VA G LEC G+P P V W +G L +I GG L +++ + D G
Sbjct: 177 VAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEG-RITIRGGKL---MMSHTLKSDAG 232
Query: 341 RYTCLATNPSGS-DTTSAEVFIEGASS----------------------TDSDSESLAFK 377
Y C+A+N +G ++ +AEV + S L ++
Sbjct: 233 MYVCVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWR 292
Query: 378 SRAGAMPQAQKKTTSV-SLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTT 436
G +P + + S SL IG S + T + SV + G+ +
Sbjct: 293 KEDGELPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEA----------SGSLS 342
Query: 437 AYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRS 496
+ PP + Q+ A G+ V +C +G PP + W ++GS++ P + LQ R
Sbjct: 343 VHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPS-QSLQPTGRF 401
Query: 497 TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTE 544
+ P L I DAG + C A + GS + A L + A+ +
Sbjct: 402 SVSPRG--QLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLD 447
Score = 66.2 bits (160), Expect = 2e-10
Identities = 53/209 (25%), Positives = 82/209 (39%), Gaps = 39/209 (18%)
Query: 791 GMPVTFTCRVAGNPKPKIYWFKDGKQI---SPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
G V F C GNP P I+W K+G Q+ +S T + + L+ TA D G
Sbjct: 361 GESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAG 420
Query: 848 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 907
Y A + G I L ++ + G
Sbjct: 421 YYVCQAVSVAGSILAKALLEIKGASLDG-------------------------------- 448
Query: 908 FFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
P LQ P + T+ G + C+V+G P P + W+ DG+ ++ D + NG
Sbjct: 449 -LPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDL-QFKTMANG-- 504
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFS 996
+L I V D G Y+C+A + G+ ++S
Sbjct: 505 TLYIANVQEMDMGFYSCVAKSSTGEATWS 533
Score = 58.5 bits (140), Expect = 3e-08
Identities = 49/149 (32%), Positives = 72/149 (48%), Gaps = 8/149 (5%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P +Q +Q + GS V+L CRVTGNP P VRW +G+ L D+Q TL
Sbjct: 451 PVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQG-DDLQFKTMANG--TLY 507
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSA--EVFIEGASSTDSDSESLAFKSRAGAMPQAQK 388
IA E D G Y+C+A + +G T S ++ + S D +E + +
Sbjct: 508 IANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGVSPDPPTEPSSPPGAPSQPVVTEI 567
Query: 389 KTTSVSLTIGSSSPKTG--VTTAVIQPLS 415
S++LT +P+TG VT+ VI+ S
Sbjct: 568 TKNSITLT-WKPNPQTGAAVTSYVIEAFS 595
Score = 52.0 bits (123), Expect = 3e-06
Identities = 66/307 (21%), Positives = 106/307 (34%), Gaps = 62/307 (20%)
Query: 269 AAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNT-PDIQIH---CEGG 324
A PR +++ V+ G L CR G P P + W+ G + D + H G
Sbjct: 62 AMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSG 121
Query: 325 DLH--TLIIAEAFEDDTGRYTCLATNPSG---SDTTSAEV-------------------- 359
L ++ D G YTC+A N G S S EV
Sbjct: 122 ALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGE 181
Query: 360 --FIEGASSTDSDSESLAFKSRAGAMPQAQKKTT------SVSLTIGSSSPKTGVTTAVI 411
+E S++++ + + + + T +S T+ S + G+ V
Sbjct: 182 PAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDA---GMYVCVA 238
Query: 412 QPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQ 471
++ + + L RP F + N V V C V+G PP +
Sbjct: 239 SNMAGERESAAAEVMVLERPS----------FLRRPVNQVVLADAPVTFLCEVKGDPPPR 288
Query: 472 VQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSAT 531
++W ++ E+ P E +L I ED G +TC A N G A
Sbjct: 289 LRWRKEDGEL------------PTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAE 336
Query: 532 STAQLVV 538
++ L V
Sbjct: 337 ASGSLSV 343
Score = 47.4 bits (111), Expect = 8e-05
Identities = 32/119 (26%), Positives = 47/119 (39%), Gaps = 4/119 (3%)
Query: 251 VPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKE 310
V N + +L P+ + + + Q A G V +C GNP P + W EG +
Sbjct: 327 VAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQ 386
Query: 311 LHNTPDIQIHCEG----GDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGAS 365
+ P + G L I D G Y C A + +GS A + I+GAS
Sbjct: 387 VLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGAS 445
Score = 40.0 bits (92), Expect = 0.012
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 773 NGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG 832
+G+ P + + G V CRV GNP+P + W KDG+ + + D + +G
Sbjct: 447 DGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWL--QGDDLQFKTMANG 504
Query: 833 TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPS 882
T + D G Y+ +A + G + +G L ++ G SP P+
Sbjct: 505 TLYIANVQEM--DMGFYSCVAKSSTGEATWSGWLKMR--EDWGVSPDPPT 550
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 99.0 bits (245), Expect = 2e-20
Identities = 99/381 (25%), Positives = 147/381 (38%), Gaps = 78/381 (20%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA-----ST 842
+ +G P T C+ G P P I W+K G+++ D R L + SL +
Sbjct: 40 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99
Query: 843 LDDDGNYTIMAANPQGR-ISCTGRLMVQAVNQRGRSPRS----------------PSGHP 885
D+G Y +A N G +S L V + R S P GHP
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHP 159
Query: 886 H--------------------VRRPR-----SRSRDSGD------------ENEPIQERF 908
+R + +R D+G E+E +
Sbjct: 160 EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTV 219
Query: 909 F-RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
RP F++ P +L V C+ G P P + W+ D + P S ++ +R++ H
Sbjct: 220 LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYE--IRDD--H 274
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
+L I VT+ D G YTC+A N G+ S L V +PP F+ K ++ VA G V
Sbjct: 275 TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--GSEPPHFVVKPRDQVVALGRTV 332
Query: 1028 RLECRVLGVPPPQIFWKKENE-------SLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
+C G P P IFW++E S+ R S+ Q L I + D G
Sbjct: 333 TFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQRSDVG 388
Query: 1081 WYTVSAKNEAGIVSCTARLDV 1101
+Y N AG + A L+V
Sbjct: 389 YYICQTLNVAGSIITKAYLEV 409
Score = 88.2 bits (217), Expect = 4e-17
Identities = 85/314 (27%), Positives = 121/314 (38%), Gaps = 57/314 (18%)
Query: 796 FTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAAN 855
F C G+P P + W KD ++ PKS Y I+ D +L T D G+YT +A N
Sbjct: 242 FKCEARGDPVPTVRWRKDDGEL-PKS-RYEIRDDH----TLKIRKVTAGDMGSYTCVAEN 295
Query: 856 PQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQ 915
G+ + L VQ G P PHF+
Sbjct: 296 MVGKAEASATLTVQV----GSEP--------------------------------PHFVV 319
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP------VRPDSAHKMLVRENGVHSL 969
P D V G+ C+ +G P P + W+ +G P S+ + V + G L
Sbjct: 320 KPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DL 377
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK--LQNTGVADGYPV 1027
I V D G Y C N AG L V A +PP I + + T DG V
Sbjct: 378 TITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFV 437
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 1087
L C G P P I W+K+ ++ R+ ++ L I+ A D G YT A
Sbjct: 438 -LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTGRYTCIAS 492
Query: 1088 NEAGIVSCTARLDV 1101
+G + +A ++V
Sbjct: 493 TPSGEATWSAYIEV 506
Score = 85.1 bits (209), Expect = 3e-16
Identities = 59/198 (29%), Positives = 93/198 (46%), Gaps = 21/198 (10%)
Query: 904 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS----AHKM 959
+++ F P ++ P DL V +G+ ++CK G PTP + W G+ V D +H+M
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 960 LVRENGVHSL-IIEPVTSR-DAGIYTCIATNRAGQ---NSFSLELVVAAKEAHKPPVFIE 1014
L+ + L I+ SR D G+Y C+A N G+ ++ SLE+ + + + P
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNP---- 137
Query: 1015 KLQNTGVADGYPVRLECR-VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQG 1073
+ VA G P +EC+ G P P I WKK+ L +R+++ L+I
Sbjct: 138 --SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITY 190
Query: 1074 ATKEDAGWYTVSAKNEAG 1091
K DAG Y N G
Sbjct: 191 TRKSDAGKYVCVGTNMVG 208
Score = 63.9 bits (154), Expect = 8e-10
Identities = 88/368 (23%), Positives = 133/368 (36%), Gaps = 52/368 (14%)
Query: 207 PKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQD----LAVPHNRKSHPQPH 262
P+ P +S SP++D+ E ++ Y D + V N +
Sbjct: 155 PRGHPEPTISWKKDGSPLDDKDE-RITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESE 213
Query: 263 SA-LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC 321
A L P F+++ + V +C G+P P VRW + EL +
Sbjct: 214 VAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-----RY 268
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD-----------SD 370
E D HTL I + D G YTC+A N G SA + ++ S +
Sbjct: 269 EIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVAL 328
Query: 371 SESLAFKSRAGAMPQAQ---KKTTSVSLTIGSSSPKTGVTTAVIQ--PLSVPVQQVHSPT 425
++ F+ A PQ ++ S +L P++ +V Q L++ Q
Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 388
Query: 426 SYLCRPDGT-----TTAYF----------PPVFTKELQNTAVAEGQVVVLECRVRGAPPL 470
Y+C+ T AY PPV + N VA VL C G+P
Sbjct: 389 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Query: 471 QVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSA 530
+ W R+ + + D RI Q E L I D G +TC A G A
Sbjct: 449 TILW-RKDGVLVSTQDSRIKQL---------ENGVLQIRYAKLGDTGRYTCIASTPSGEA 498
Query: 531 TSTAQLVV 538
T +A + V
Sbjct: 499 TWSAYIEV 506
Score = 62.8 bits (151), Expect = 2e-09
Identities = 68/242 (28%), Positives = 91/242 (37%), Gaps = 47/242 (19%)
Query: 764 VQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ---ISPK 820
VQ G P P F +K + + G VTF C GNP+P I+W ++G Q S +
Sbjct: 308 VQVGSEP------PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQ 361
Query: 821 SDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRS 880
+ + + T L T D G Y N G I L V V + R
Sbjct: 362 PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDV----IADRP 417
Query: 881 PSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTP 940
P P Q P + TV + C +G P P
Sbjct: 418 P-----------------------------PVIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Query: 941 DLSWQLDGKPV-RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL 999
+ W+ DG V DS K L ENGV L I D G YTCIA+ +G+ ++S +
Sbjct: 449 TILWRKDGVLVSTQDSRIKQL--ENGV--LQIRYAKLGDTGRYTCIASTPSGEATWSAYI 504
Query: 1000 VV 1001
V
Sbjct: 505 EV 506
Score = 61.6 bits (148), Expect = 4e-09
Identities = 71/292 (24%), Positives = 102/292 (34%), Gaps = 36/292 (12%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD----IQIHCEGGDL 326
PR ++ V++G L C+ G PTP + W+ G+ + D ++ G L
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 327 HTLIIAEAFED--DTGRYTCLATNPSG---SDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
L I + D G Y C+A N G S S EV I + S+ +
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPA 148
Query: 382 AM----PQAQKKTTSVSLTIGSS-SPKTGVTTAVIQPLSVPVQQVHSPTSYLC------- 429
M P+ + T GS K T L + + Y+C
Sbjct: 149 VMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVG 208
Query: 430 ---RPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
T P F K N AV +C RG P V+W + E+
Sbjct: 209 ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL----- 263
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P+S E + TL I + D G +TC A N G A ++A L V
Sbjct: 264 -------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Score = 61.2 bits (147), Expect = 5e-09
Identities = 85/355 (23%), Positives = 131/355 (36%), Gaps = 52/355 (14%)
Query: 282 VAEGSRVYLECRVT-GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
VA G +EC+ G+P P + W +G L + D +I GG L +I + D G
Sbjct: 142 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGKL---MITYTRKSDAG 197
Query: 341 RYTCLATNPSGS-DTTSAEV-------FIEGASS---TDSDSESLAFKSRAGAMPQAQKK 389
+Y C+ TN G ++ AE+ F++ S+ T DS ++R +P + +
Sbjct: 198 KYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR 257
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---------RPDGTTTAYF- 439
L PK+ L + SY C T T
Sbjct: 258 KDDGEL------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVG 311
Query: 440 --PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
PP F + ++ VA G+ V +C G P + W R+GS+ + + P+S+
Sbjct: 312 SEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQ-----NLLFSYQPPQSS 366
Query: 498 A--EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTE----------- 544
+ + L I D G + C N GS + A L VT +
Sbjct: 367 SRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPV 426
Query: 545 NCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAAL 599
N + G P P IL L S + S I+Q+ N L + A L
Sbjct: 427 NQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 481
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/85 (40%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI-HCEGGDLHTLIIAEAFED 337
+Q VA L C TG+P P + W +G L +T D +I E G L I A
Sbjct: 427 NQTVAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIKQLENGVLQ---IRYAKLG 482
Query: 338 DTGRYTCLATNPSGSDTTSAEVFIE 362
DTGRYTC+A+ PSG T SA + ++
Sbjct: 483 DTGRYTCIASTPSGEATWSAYIEVQ 507
Score = 50.1 bits (118), Expect = 1e-05
Identities = 101/467 (21%), Positives = 172/467 (36%), Gaps = 112/467 (23%)
Query: 443 FTKELQNTAVAEGQVVVLECRV-RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
F + + VA G+ V+EC+ RG P + W + GS + D D RI + +
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGK------ 185
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATS-TAQLVVTS-----------ANTENCSYE 549
L+I T DAG + C N G S A+L V A T + S E
Sbjct: 186 ----LMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAE 241
Query: 550 SMGESNNDHFQHFPPPPPI--------LETSSLELASKKPSEIQQVNNPELGLSRAALQM 601
E+ D P P + L S E+ +I++V ++G +
Sbjct: 242 FKCEARGD------PVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAEN 295
Query: 602 QFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKA 661
GKA ++ +L EPP + KP+
Sbjct: 296 MV---------------------GKAEASATLTVQV-----GSEPPHFVVKPR------- 322
Query: 662 SRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVF 721
D V+ L R + F+ + N QP + + ++ LL F
Sbjct: 323 ----------------DQVVA-LGRTVTFQCEATGNPQPAIFWRREGSQNLL-------F 358
Query: 722 NIQEPEEETANQEYKVSSCEQRLI-----SEIEYRLERSPVDESGDEVQYGDVPVENGMA 776
+ Q P+ ++ + VS I S++ Y + ++ ++ +G + + V + +A
Sbjct: 359 SYQPPQ---SSSRFSVSQTGDLTITNVQRSDVGYYICQT-LNVAGSIITKAYLEVTDVIA 414
Query: 777 PFFEMKLKHYKIFEGMPVTFT----CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG 832
++ + + + V T C G+P P I W KDG +S + I++ +G
Sbjct: 415 DRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSR--IKQLENG 472
Query: 833 TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPR 879
L + L D G YT +A+ P G + + + VQ + PR
Sbjct: 473 V--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPR 517
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/110 (24%), Positives = 43/110 (39%), Gaps = 11/110 (10%)
Query: 428 LCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
LC FPP + + V++G+ L C+ G P ++W++ G ++ D
Sbjct: 16 LCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKD- 74
Query: 488 RILQKKPRS-----TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATS 532
PRS + +V D G++ C ARN G A S
Sbjct: 75 -----DPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVS 119
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 99.0 bits (245), Expect = 2e-20
Identities = 99/381 (25%), Positives = 147/381 (38%), Gaps = 78/381 (20%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA-----ST 842
+ +G P T C+ G P P I W+K G+++ D R L + SL +
Sbjct: 40 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99
Query: 843 LDDDGNYTIMAANPQGR-ISCTGRLMVQAVNQRGRSPRS----------------PSGHP 885
D+G Y +A N G +S L V + R S P GHP
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHP 159
Query: 886 H--------------------VRRPR-----SRSRDSGD------------ENEPIQERF 908
+R + +R D+G E+E +
Sbjct: 160 EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTV 219
Query: 909 F-RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
RP F++ P +L V C+ G P P + W+ D + P S ++ +R++ H
Sbjct: 220 LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYE--IRDD--H 274
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
+L I VT+ D G YTC+A N G+ S L V +PP F+ K ++ VA G V
Sbjct: 275 TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--GSEPPHFVVKPRDQVVALGRTV 332
Query: 1028 RLECRVLGVPPPQIFWKKENE-------SLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
+C G P P IFW++E S+ R S+ Q L I + D G
Sbjct: 333 TFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQRSDVG 388
Query: 1081 WYTVSAKNEAGIVSCTARLDV 1101
+Y N AG + A L+V
Sbjct: 389 YYICQTLNVAGSIITKAYLEV 409
Score = 88.2 bits (217), Expect = 4e-17
Identities = 85/314 (27%), Positives = 121/314 (38%), Gaps = 57/314 (18%)
Query: 796 FTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAAN 855
F C G+P P + W KD ++ PKS Y I+ D +L T D G+YT +A N
Sbjct: 242 FKCEARGDPVPTVRWRKDDGEL-PKS-RYEIRDDH----TLKIRKVTAGDMGSYTCVAEN 295
Query: 856 PQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQ 915
G+ + L VQ G P PHF+
Sbjct: 296 MVGKAEASATLTVQV----GSEP--------------------------------PHFVV 319
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP------VRPDSAHKMLVRENGVHSL 969
P D V G+ C+ +G P P + W+ +G P S+ + V + G L
Sbjct: 320 KPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DL 377
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK--LQNTGVADGYPV 1027
I V D G Y C N AG L V A +PP I + + T DG V
Sbjct: 378 TITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFV 437
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 1087
L C G P P I W+K+ ++ R+ ++ L I+ A D G YT A
Sbjct: 438 -LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTGRYTCIAS 492
Query: 1088 NEAGIVSCTARLDV 1101
+G + +A ++V
Sbjct: 493 TPSGEATWSAYIEV 506
Score = 85.1 bits (209), Expect = 3e-16
Identities = 59/198 (29%), Positives = 93/198 (46%), Gaps = 21/198 (10%)
Query: 904 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS----AHKM 959
+++ F P ++ P DL V +G+ ++CK G PTP + W G+ V D +H+M
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 960 LVRENGVHSL-IIEPVTSR-DAGIYTCIATNRAGQ---NSFSLELVVAAKEAHKPPVFIE 1014
L+ + L I+ SR D G+Y C+A N G+ ++ SLE+ + + + P
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNP---- 137
Query: 1015 KLQNTGVADGYPVRLECR-VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQG 1073
+ VA G P +EC+ G P P I WKK+ L +R+++ L+I
Sbjct: 138 --SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITY 190
Query: 1074 ATKEDAGWYTVSAKNEAG 1091
K DAG Y N G
Sbjct: 191 TRKSDAGKYVCVGTNMVG 208
Score = 63.9 bits (154), Expect = 8e-10
Identities = 88/368 (23%), Positives = 133/368 (36%), Gaps = 52/368 (14%)
Query: 207 PKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQD----LAVPHNRKSHPQPH 262
P+ P +S SP++D+ E ++ Y D + V N +
Sbjct: 155 PRGHPEPTISWKKDGSPLDDKDE-RITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESE 213
Query: 263 SA-LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC 321
A L P F+++ + V +C G+P P VRW + EL +
Sbjct: 214 VAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-----RY 268
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD-----------SD 370
E D HTL I + D G YTC+A N G SA + ++ S +
Sbjct: 269 EIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVAL 328
Query: 371 SESLAFKSRAGAMPQAQ---KKTTSVSLTIGSSSPKTGVTTAVIQ--PLSVPVQQVHSPT 425
++ F+ A PQ ++ S +L P++ +V Q L++ Q
Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 388
Query: 426 SYLCRPDGT-----TTAYF----------PPVFTKELQNTAVAEGQVVVLECRVRGAPPL 470
Y+C+ T AY PPV + N VA VL C G+P
Sbjct: 389 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Query: 471 QVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSA 530
+ W R+ + + D RI Q E L I D G +TC A G A
Sbjct: 449 TILW-RKDGVLVSTQDSRIKQL---------ENGVLQIRYAKLGDTGRYTCIASTPSGEA 498
Query: 531 TSTAQLVV 538
T +A + V
Sbjct: 499 TWSAYIEV 506
Score = 62.8 bits (151), Expect = 2e-09
Identities = 68/242 (28%), Positives = 91/242 (37%), Gaps = 47/242 (19%)
Query: 764 VQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ---ISPK 820
VQ G P P F +K + + G VTF C GNP+P I+W ++G Q S +
Sbjct: 308 VQVGSEP------PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQ 361
Query: 821 SDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRS 880
+ + + T L T D G Y N G I L V V + R
Sbjct: 362 PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDV----IADRP 417
Query: 881 PSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTP 940
P P Q P + TV + C +G P P
Sbjct: 418 P-----------------------------PVIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Query: 941 DLSWQLDGKPV-RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL 999
+ W+ DG V DS K L ENGV L I D G YTCIA+ +G+ ++S +
Sbjct: 449 TILWRKDGVLVSTQDSRIKQL--ENGV--LQIRYAKLGDTGRYTCIASTPSGEATWSAYI 504
Query: 1000 VV 1001
V
Sbjct: 505 EV 506
Score = 61.6 bits (148), Expect = 4e-09
Identities = 71/292 (24%), Positives = 102/292 (34%), Gaps = 36/292 (12%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD----IQIHCEGGDL 326
PR ++ V++G L C+ G PTP + W+ G+ + D ++ G L
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 327 HTLIIAEAFED--DTGRYTCLATNPSG---SDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
L I + D G Y C+A N G S S EV I + S+ +
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPA 148
Query: 382 AM----PQAQKKTTSVSLTIGSS-SPKTGVTTAVIQPLSVPVQQVHSPTSYLC------- 429
M P+ + T GS K T L + + Y+C
Sbjct: 149 VMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVG 208
Query: 430 ---RPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
T P F K N AV +C RG P V+W + E+
Sbjct: 209 ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL----- 263
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P+S E + TL I + D G +TC A N G A ++A L V
Sbjct: 264 -------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Score = 61.2 bits (147), Expect = 5e-09
Identities = 85/355 (23%), Positives = 131/355 (36%), Gaps = 52/355 (14%)
Query: 282 VAEGSRVYLECRVT-GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
VA G +EC+ G+P P + W +G L + D +I GG L +I + D G
Sbjct: 142 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGKL---MITYTRKSDAG 197
Query: 341 RYTCLATNPSGS-DTTSAEV-------FIEGASS---TDSDSESLAFKSRAGAMPQAQKK 389
+Y C+ TN G ++ AE+ F++ S+ T DS ++R +P + +
Sbjct: 198 KYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR 257
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---------RPDGTTTAYF- 439
L PK+ L + SY C T T
Sbjct: 258 KDDGEL------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVG 311
Query: 440 --PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
PP F + ++ VA G+ V +C G P + W R+GS+ + + P+S+
Sbjct: 312 SEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQ-----NLLFSYQPPQSS 366
Query: 498 A--EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTE----------- 544
+ + L I D G + C N GS + A L VT +
Sbjct: 367 SRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPV 426
Query: 545 NCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAAL 599
N + G P P IL L S + S I+Q+ N L + A L
Sbjct: 427 NQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 481
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/85 (40%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI-HCEGGDLHTLIIAEAFED 337
+Q VA L C TG+P P + W +G L +T D +I E G L I A
Sbjct: 427 NQTVAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIKQLENGVLQ---IRYAKLG 482
Query: 338 DTGRYTCLATNPSGSDTTSAEVFIE 362
DTGRYTC+A+ PSG T SA + ++
Sbjct: 483 DTGRYTCIASTPSGEATWSAYIEVQ 507
Score = 50.1 bits (118), Expect = 1e-05
Identities = 101/467 (21%), Positives = 172/467 (36%), Gaps = 112/467 (23%)
Query: 443 FTKELQNTAVAEGQVVVLECRV-RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
F + + VA G+ V+EC+ RG P + W + GS + D D RI + +
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGK------ 185
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATS-TAQLVVTS-----------ANTENCSYE 549
L+I T DAG + C N G S A+L V A T + S E
Sbjct: 186 ----LMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAE 241
Query: 550 SMGESNNDHFQHFPPPPPI--------LETSSLELASKKPSEIQQVNNPELGLSRAALQM 601
E+ D P P + L S E+ +I++V ++G +
Sbjct: 242 FKCEARGD------PVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAEN 295
Query: 602 QFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKA 661
GKA ++ +L EPP + KP+
Sbjct: 296 MV---------------------GKAEASATLTVQV-----GSEPPHFVVKPR------- 322
Query: 662 SRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVF 721
D V+ L R + F+ + N QP + + ++ LL F
Sbjct: 323 ----------------DQVVA-LGRTVTFQCEATGNPQPAIFWRREGSQNLL-------F 358
Query: 722 NIQEPEEETANQEYKVSSCEQRLI-----SEIEYRLERSPVDESGDEVQYGDVPVENGMA 776
+ Q P+ ++ + VS I S++ Y + ++ ++ +G + + V + +A
Sbjct: 359 SYQPPQ---SSSRFSVSQTGDLTITNVQRSDVGYYICQT-LNVAGSIITKAYLEVTDVIA 414
Query: 777 PFFEMKLKHYKIFEGMPVTFT----CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG 832
++ + + + V T C G+P P I W KDG +S + I++ +G
Sbjct: 415 DRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSR--IKQLENG 472
Query: 833 TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPR 879
L + L D G YT +A+ P G + + + VQ + PR
Sbjct: 473 V--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPR 517
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/110 (24%), Positives = 43/110 (39%), Gaps = 11/110 (10%)
Query: 428 LCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
LC FPP + + V++G+ L C+ G P ++W++ G ++ D
Sbjct: 16 LCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKD- 74
Query: 488 RILQKKPRS-----TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATS 532
PRS + +V D G++ C ARN G A S
Sbjct: 75 -----DPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVS 119
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 99.0 bits (245), Expect = 2e-20
Identities = 99/381 (25%), Positives = 147/381 (38%), Gaps = 78/381 (20%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA-----ST 842
+ +G P T C+ G P P I W+K G+++ D R L + SL +
Sbjct: 40 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99
Query: 843 LDDDGNYTIMAANPQGR-ISCTGRLMVQAVNQRGRSPRS----------------PSGHP 885
D+G Y +A N G +S L V + R S P GHP
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHP 159
Query: 886 H--------------------VRRPR-----SRSRDSGD------------ENEPIQERF 908
+R + +R D+G E+E +
Sbjct: 160 EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTV 219
Query: 909 F-RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
RP F++ P +L V C+ G P P + W+ D + P S ++ +R++ H
Sbjct: 220 LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYE--IRDD--H 274
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
+L I VT+ D G YTC+A N G+ S L V +PP F+ K ++ VA G V
Sbjct: 275 TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--GSEPPHFVVKPRDQVVALGRTV 332
Query: 1028 RLECRVLGVPPPQIFWKKENE-------SLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
+C G P P IFW++E S+ R S+ Q L I + D G
Sbjct: 333 TFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQRSDVG 388
Query: 1081 WYTVSAKNEAGIVSCTARLDV 1101
+Y N AG + A L+V
Sbjct: 389 YYICQTLNVAGSIITKAYLEV 409
Score = 88.2 bits (217), Expect = 4e-17
Identities = 85/314 (27%), Positives = 121/314 (38%), Gaps = 57/314 (18%)
Query: 796 FTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAAN 855
F C G+P P + W KD ++ PKS Y I+ D +L T D G+YT +A N
Sbjct: 242 FKCEARGDPVPTVRWRKDDGEL-PKS-RYEIRDDH----TLKIRKVTAGDMGSYTCVAEN 295
Query: 856 PQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQ 915
G+ + L VQ G P PHF+
Sbjct: 296 MVGKAEASATLTVQV----GSEP--------------------------------PHFVV 319
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP------VRPDSAHKMLVRENGVHSL 969
P D V G+ C+ +G P P + W+ +G P S+ + V + G L
Sbjct: 320 KPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DL 377
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK--LQNTGVADGYPV 1027
I V D G Y C N AG L V A +PP I + + T DG V
Sbjct: 378 TITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFV 437
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 1087
L C G P P I W+K+ ++ R+ ++ L I+ A D G YT A
Sbjct: 438 -LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTGRYTCIAS 492
Query: 1088 NEAGIVSCTARLDV 1101
+G + +A ++V
Sbjct: 493 TPSGEATWSAYIEV 506
Score = 85.1 bits (209), Expect = 3e-16
Identities = 59/198 (29%), Positives = 93/198 (46%), Gaps = 21/198 (10%)
Query: 904 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS----AHKM 959
+++ F P ++ P DL V +G+ ++CK G PTP + W G+ V D +H+M
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 960 LVRENGVHSL-IIEPVTSR-DAGIYTCIATNRAGQ---NSFSLELVVAAKEAHKPPVFIE 1014
L+ + L I+ SR D G+Y C+A N G+ ++ SLE+ + + + P
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNP---- 137
Query: 1015 KLQNTGVADGYPVRLECR-VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQG 1073
+ VA G P +EC+ G P P I WKK+ L +R+++ L+I
Sbjct: 138 --SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITY 190
Query: 1074 ATKEDAGWYTVSAKNEAG 1091
K DAG Y N G
Sbjct: 191 TRKSDAGKYVCVGTNMVG 208
Score = 63.9 bits (154), Expect = 8e-10
Identities = 88/368 (23%), Positives = 133/368 (36%), Gaps = 52/368 (14%)
Query: 207 PKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQD----LAVPHNRKSHPQPH 262
P+ P +S SP++D+ E ++ Y D + V N +
Sbjct: 155 PRGHPEPTISWKKDGSPLDDKDE-RITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESE 213
Query: 263 SA-LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC 321
A L P F+++ + V +C G+P P VRW + EL +
Sbjct: 214 VAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-----RY 268
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD-----------SD 370
E D HTL I + D G YTC+A N G SA + ++ S +
Sbjct: 269 EIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVAL 328
Query: 371 SESLAFKSRAGAMPQAQ---KKTTSVSLTIGSSSPKTGVTTAVIQ--PLSVPVQQVHSPT 425
++ F+ A PQ ++ S +L P++ +V Q L++ Q
Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 388
Query: 426 SYLCRPDGT-----TTAYF----------PPVFTKELQNTAVAEGQVVVLECRVRGAPPL 470
Y+C+ T AY PPV + N VA VL C G+P
Sbjct: 389 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Query: 471 QVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSA 530
+ W R+ + + D RI Q E L I D G +TC A G A
Sbjct: 449 TILW-RKDGVLVSTQDSRIKQL---------ENGVLQIRYAKLGDTGRYTCIASTPSGEA 498
Query: 531 TSTAQLVV 538
T +A + V
Sbjct: 499 TWSAYIEV 506
Score = 62.8 bits (151), Expect = 2e-09
Identities = 68/242 (28%), Positives = 91/242 (37%), Gaps = 47/242 (19%)
Query: 764 VQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ---ISPK 820
VQ G P P F +K + + G VTF C GNP+P I+W ++G Q S +
Sbjct: 308 VQVGSEP------PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQ 361
Query: 821 SDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRS 880
+ + + T L T D G Y N G I L V V + R
Sbjct: 362 PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDV----IADRP 417
Query: 881 PSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTP 940
P P Q P + TV + C +G P P
Sbjct: 418 P-----------------------------PVIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Query: 941 DLSWQLDGKPV-RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL 999
+ W+ DG V DS K L ENGV L I D G YTCIA+ +G+ ++S +
Sbjct: 449 TILWRKDGVLVSTQDSRIKQL--ENGV--LQIRYAKLGDTGRYTCIASTPSGEATWSAYI 504
Query: 1000 VV 1001
V
Sbjct: 505 EV 506
Score = 61.6 bits (148), Expect = 4e-09
Identities = 71/292 (24%), Positives = 102/292 (34%), Gaps = 36/292 (12%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD----IQIHCEGGDL 326
PR ++ V++G L C+ G PTP + W+ G+ + D ++ G L
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 327 HTLIIAEAFED--DTGRYTCLATNPSG---SDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
L I + D G Y C+A N G S S EV I + S+ +
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPA 148
Query: 382 AM----PQAQKKTTSVSLTIGSS-SPKTGVTTAVIQPLSVPVQQVHSPTSYLC------- 429
M P+ + T GS K T L + + Y+C
Sbjct: 149 VMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVG 208
Query: 430 ---RPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
T P F K N AV +C RG P V+W + E+
Sbjct: 209 ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL----- 263
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P+S E + TL I + D G +TC A N G A ++A L V
Sbjct: 264 -------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Score = 61.2 bits (147), Expect = 5e-09
Identities = 85/355 (23%), Positives = 131/355 (36%), Gaps = 52/355 (14%)
Query: 282 VAEGSRVYLECRVT-GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
VA G +EC+ G+P P + W +G L + D +I GG L +I + D G
Sbjct: 142 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGKL---MITYTRKSDAG 197
Query: 341 RYTCLATNPSGS-DTTSAEV-------FIEGASS---TDSDSESLAFKSRAGAMPQAQKK 389
+Y C+ TN G ++ AE+ F++ S+ T DS ++R +P + +
Sbjct: 198 KYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR 257
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---------RPDGTTTAYF- 439
L PK+ L + SY C T T
Sbjct: 258 KDDGEL------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVG 311
Query: 440 --PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
PP F + ++ VA G+ V +C G P + W R+GS+ + + P+S+
Sbjct: 312 SEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQ-----NLLFSYQPPQSS 366
Query: 498 A--EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTE----------- 544
+ + L I D G + C N GS + A L VT +
Sbjct: 367 SRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPV 426
Query: 545 NCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAAL 599
N + G P P IL L S + S I+Q+ N L + A L
Sbjct: 427 NQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 481
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/85 (40%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI-HCEGGDLHTLIIAEAFED 337
+Q VA L C TG+P P + W +G L +T D +I E G L I A
Sbjct: 427 NQTVAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIKQLENGVLQ---IRYAKLG 482
Query: 338 DTGRYTCLATNPSGSDTTSAEVFIE 362
DTGRYTC+A+ PSG T SA + ++
Sbjct: 483 DTGRYTCIASTPSGEATWSAYIEVQ 507
Score = 50.1 bits (118), Expect = 1e-05
Identities = 101/467 (21%), Positives = 172/467 (36%), Gaps = 112/467 (23%)
Query: 443 FTKELQNTAVAEGQVVVLECRV-RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
F + + VA G+ V+EC+ RG P + W + GS + D D RI + +
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGK------ 185
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATS-TAQLVVTS-----------ANTENCSYE 549
L+I T DAG + C N G S A+L V A T + S E
Sbjct: 186 ----LMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAE 241
Query: 550 SMGESNNDHFQHFPPPPPI--------LETSSLELASKKPSEIQQVNNPELGLSRAALQM 601
E+ D P P + L S E+ +I++V ++G +
Sbjct: 242 FKCEARGD------PVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAEN 295
Query: 602 QFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKA 661
GKA ++ +L EPP + KP+
Sbjct: 296 MV---------------------GKAEASATLTVQV-----GSEPPHFVVKPR------- 322
Query: 662 SRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVF 721
D V+ L R + F+ + N QP + + ++ LL F
Sbjct: 323 ----------------DQVVA-LGRTVTFQCEATGNPQPAIFWRREGSQNLL-------F 358
Query: 722 NIQEPEEETANQEYKVSSCEQRLI-----SEIEYRLERSPVDESGDEVQYGDVPVENGMA 776
+ Q P+ ++ + VS I S++ Y + ++ ++ +G + + V + +A
Sbjct: 359 SYQPPQ---SSSRFSVSQTGDLTITNVQRSDVGYYICQT-LNVAGSIITKAYLEVTDVIA 414
Query: 777 PFFEMKLKHYKIFEGMPVTFT----CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG 832
++ + + + V T C G+P P I W KDG +S + I++ +G
Sbjct: 415 DRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSR--IKQLENG 472
Query: 833 TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPR 879
L + L D G YT +A+ P G + + + VQ + PR
Sbjct: 473 V--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPR 517
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/110 (24%), Positives = 43/110 (39%), Gaps = 11/110 (10%)
Query: 428 LCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
LC FPP + + V++G+ L C+ G P ++W++ G ++ D
Sbjct: 16 LCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKD- 74
Query: 488 RILQKKPRS-----TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATS 532
PRS + +V D G++ C ARN G A S
Sbjct: 75 -----DPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVS 119
>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
sapiens]
Length = 1615
Score = 99.0 bits (245), Expect = 2e-20
Identities = 99/381 (25%), Positives = 147/381 (38%), Gaps = 78/381 (20%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA-----ST 842
+ +G P T C+ G P P I W+K G+++ D R L + SL +
Sbjct: 40 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99
Query: 843 LDDDGNYTIMAANPQGR-ISCTGRLMVQAVNQRGRSPRS----------------PSGHP 885
D+G Y +A N G +S L V + R S P GHP
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHP 159
Query: 886 H--------------------VRRPR-----SRSRDSGD------------ENEPIQERF 908
+R + +R D+G E+E +
Sbjct: 160 EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTV 219
Query: 909 F-RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
RP F++ P +L V C+ G P P + W+ D + P S ++ +R++ H
Sbjct: 220 LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYE--IRDD--H 274
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
+L I VT+ D G YTC+A N G+ S L V +PP F+ K ++ VA G V
Sbjct: 275 TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQV--GSEPPHFVVKPRDQVVALGRTV 332
Query: 1028 RLECRVLGVPPPQIFWKKENE-------SLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
+C G P P IFW++E S+ R S+ Q L I + D G
Sbjct: 333 TFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQRSDVG 388
Query: 1081 WYTVSAKNEAGIVSCTARLDV 1101
+Y N AG + A L+V
Sbjct: 389 YYICQTLNVAGSIITKAYLEV 409
Score = 88.2 bits (217), Expect = 4e-17
Identities = 85/314 (27%), Positives = 121/314 (38%), Gaps = 57/314 (18%)
Query: 796 FTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAAN 855
F C G+P P + W KD ++ PKS Y I+ D +L T D G+YT +A N
Sbjct: 242 FKCEARGDPVPTVRWRKDDGEL-PKS-RYEIRDDH----TLKIRKVTAGDMGSYTCVAEN 295
Query: 856 PQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQ 915
G+ + L VQ G P PHF+
Sbjct: 296 MVGKAEASATLTVQV----GSEP--------------------------------PHFVV 319
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP------VRPDSAHKMLVRENGVHSL 969
P D V G+ C+ +G P P + W+ +G P S+ + V + G L
Sbjct: 320 KPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DL 377
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK--LQNTGVADGYPV 1027
I V D G Y C N AG L V A +PP I + + T DG V
Sbjct: 378 TITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFV 437
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 1087
L C G P P I W+K+ ++ R+ ++ L I+ A D G YT A
Sbjct: 438 -LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTGRYTCIAS 492
Query: 1088 NEAGIVSCTARLDV 1101
+G + +A ++V
Sbjct: 493 TPSGEATWSAYIEV 506
Score = 85.1 bits (209), Expect = 3e-16
Identities = 59/198 (29%), Positives = 93/198 (46%), Gaps = 21/198 (10%)
Query: 904 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS----AHKM 959
+++ F P ++ P DL V +G+ ++CK G PTP + W G+ V D +H+M
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 960 LVRENGVHSL-IIEPVTSR-DAGIYTCIATNRAGQ---NSFSLELVVAAKEAHKPPVFIE 1014
L+ + L I+ SR D G+Y C+A N G+ ++ SLE+ + + + P
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNP---- 137
Query: 1015 KLQNTGVADGYPVRLECR-VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQG 1073
+ VA G P +EC+ G P P I WKK+ L +R+++ L+I
Sbjct: 138 --SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITY 190
Query: 1074 ATKEDAGWYTVSAKNEAG 1091
K DAG Y N G
Sbjct: 191 TRKSDAGKYVCVGTNMVG 208
Score = 63.9 bits (154), Expect = 8e-10
Identities = 88/368 (23%), Positives = 133/368 (36%), Gaps = 52/368 (14%)
Query: 207 PKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQD----LAVPHNRKSHPQPH 262
P+ P +S SP++D+ E ++ Y D + V N +
Sbjct: 155 PRGHPEPTISWKKDGSPLDDKDE-RITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESE 213
Query: 263 SA-LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC 321
A L P F+++ + V +C G+P P VRW + EL +
Sbjct: 214 VAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-----RY 268
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD-----------SD 370
E D HTL I + D G YTC+A N G SA + ++ S +
Sbjct: 269 EIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVAL 328
Query: 371 SESLAFKSRAGAMPQAQ---KKTTSVSLTIGSSSPKTGVTTAVIQ--PLSVPVQQVHSPT 425
++ F+ A PQ ++ S +L P++ +V Q L++ Q
Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 388
Query: 426 SYLCRPDGT-----TTAYF----------PPVFTKELQNTAVAEGQVVVLECRVRGAPPL 470
Y+C+ T AY PPV + N VA VL C G+P
Sbjct: 389 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Query: 471 QVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSA 530
+ W R+ + + D RI Q E L I D G +TC A G A
Sbjct: 449 TILW-RKDGVLVSTQDSRIKQL---------ENGVLQIRYAKLGDTGRYTCIASTPSGEA 498
Query: 531 TSTAQLVV 538
T +A + V
Sbjct: 499 TWSAYIEV 506
Score = 62.8 bits (151), Expect = 2e-09
Identities = 68/242 (28%), Positives = 91/242 (37%), Gaps = 47/242 (19%)
Query: 764 VQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ---ISPK 820
VQ G P P F +K + + G VTF C GNP+P I+W ++G Q S +
Sbjct: 308 VQVGSEP------PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQ 361
Query: 821 SDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRS 880
+ + + T L T D G Y N G I L V V + R
Sbjct: 362 PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDV----IADRP 417
Query: 881 PSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTP 940
P P Q P + TV + C +G P P
Sbjct: 418 P-----------------------------PVIRQGPVNQTVAVDGTFVLSCVATGSPVP 448
Query: 941 DLSWQLDGKPV-RPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLEL 999
+ W+ DG V DS K L ENGV L I D G YTCIA+ +G+ ++S +
Sbjct: 449 TILWRKDGVLVSTQDSRIKQL--ENGV--LQIRYAKLGDTGRYTCIASTPSGEATWSAYI 504
Query: 1000 VV 1001
V
Sbjct: 505 EV 506
Score = 61.6 bits (148), Expect = 4e-09
Identities = 71/292 (24%), Positives = 102/292 (34%), Gaps = 36/292 (12%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD----IQIHCEGGDL 326
PR ++ V++G L C+ G PTP + W+ G+ + D ++ G L
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 327 HTLIIAEAFED--DTGRYTCLATNPSG---SDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
L I + D G Y C+A N G S S EV I + S+ +
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPA 148
Query: 382 AM----PQAQKKTTSVSLTIGSS-SPKTGVTTAVIQPLSVPVQQVHSPTSYLC------- 429
M P+ + T GS K T L + + Y+C
Sbjct: 149 VMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVG 208
Query: 430 ---RPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
T P F K N AV +C RG P V+W + E+
Sbjct: 209 ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL----- 263
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P+S E + TL I + D G +TC A N G A ++A L V
Sbjct: 264 -------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Score = 61.2 bits (147), Expect = 5e-09
Identities = 85/355 (23%), Positives = 131/355 (36%), Gaps = 52/355 (14%)
Query: 282 VAEGSRVYLECRVT-GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
VA G +EC+ G+P P + W +G L + D +I GG L +I + D G
Sbjct: 142 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGKL---MITYTRKSDAG 197
Query: 341 RYTCLATNPSGS-DTTSAEV-------FIEGASS---TDSDSESLAFKSRAGAMPQAQKK 389
+Y C+ TN G ++ AE+ F++ S+ T DS ++R +P + +
Sbjct: 198 KYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR 257
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---------RPDGTTTAYF- 439
L PK+ L + SY C T T
Sbjct: 258 KDDGEL------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVG 311
Query: 440 --PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRST 497
PP F + ++ VA G+ V +C G P + W R+GS+ + + P+S+
Sbjct: 312 SEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQ-----NLLFSYQPPQSS 366
Query: 498 A--EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTE----------- 544
+ + L I D G + C N GS + A L VT +
Sbjct: 367 SRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPV 426
Query: 545 NCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAAL 599
N + G P P IL L S + S I+Q+ N L + A L
Sbjct: 427 NQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 481
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/85 (40%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI-HCEGGDLHTLIIAEAFED 337
+Q VA L C TG+P P + W +G L +T D +I E G L I A
Sbjct: 427 NQTVAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIKQLENGVLQ---IRYAKLG 482
Query: 338 DTGRYTCLATNPSGSDTTSAEVFIE 362
DTGRYTC+A+ PSG T SA + ++
Sbjct: 483 DTGRYTCIASTPSGEATWSAYIEVQ 507
Score = 50.1 bits (118), Expect = 1e-05
Identities = 101/467 (21%), Positives = 172/467 (36%), Gaps = 112/467 (23%)
Query: 443 FTKELQNTAVAEGQVVVLECRV-RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
F + + VA G+ V+EC+ RG P + W + GS + D D RI + +
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGK------ 185
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATS-TAQLVVTS-----------ANTENCSYE 549
L+I T DAG + C N G S A+L V A T + S E
Sbjct: 186 ----LMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAE 241
Query: 550 SMGESNNDHFQHFPPPPPI--------LETSSLELASKKPSEIQQVNNPELGLSRAALQM 601
E+ D P P + L S E+ +I++V ++G +
Sbjct: 242 FKCEARGD------PVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAEN 295
Query: 602 QFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKA 661
GKA ++ +L EPP + KP+
Sbjct: 296 MV---------------------GKAEASATLTVQV-----GSEPPHFVVKPR------- 322
Query: 662 SRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVF 721
D V+ L R + F+ + N QP + + ++ LL F
Sbjct: 323 ----------------DQVVA-LGRTVTFQCEATGNPQPAIFWRREGSQNLL-------F 358
Query: 722 NIQEPEEETANQEYKVSSCEQRLI-----SEIEYRLERSPVDESGDEVQYGDVPVENGMA 776
+ Q P+ ++ + VS I S++ Y + ++ ++ +G + + V + +A
Sbjct: 359 SYQPPQ---SSSRFSVSQTGDLTITNVQRSDVGYYICQT-LNVAGSIITKAYLEVTDVIA 414
Query: 777 PFFEMKLKHYKIFEGMPVTFT----CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG 832
++ + + + V T C G+P P I W KDG +S + I++ +G
Sbjct: 415 DRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSR--IKQLENG 472
Query: 833 TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPR 879
L + L D G YT +A+ P G + + + VQ + PR
Sbjct: 473 V--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPR 517
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/110 (24%), Positives = 43/110 (39%), Gaps = 11/110 (10%)
Query: 428 LCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
LC FPP + + V++G+ L C+ G P ++W++ G ++ D
Sbjct: 16 LCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKD- 74
Query: 488 RILQKKPRS-----TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATS 532
PRS + +V D G++ C ARN G A S
Sbjct: 75 -----DPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVS 119
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 98.6 bits (244), Expect = 3e-20
Identities = 99/381 (25%), Positives = 147/381 (38%), Gaps = 81/381 (21%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA-----ST 842
+ +G P T C+ G P P I W+K G+++ D R L + SL +
Sbjct: 40 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 99
Query: 843 LDDDGNYTIMAANPQGR-ISCTGRLMVQAVNQRGRSPRS----------------PSGHP 885
D+G Y +A N G +S L V + R S P GHP
Sbjct: 100 RPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHP 159
Query: 886 H--------------------VRRPR-----SRSRDSGD------------ENEPIQERF 908
+R + +R D+G E+E +
Sbjct: 160 EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTV 219
Query: 909 F-RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
RP F++ P +L V C+ G P P + W+ D + P S ++ +R++ H
Sbjct: 220 LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYE--IRDD--H 274
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
+L I VT+ D G YTC+A N G+ S L V +PP F+ K ++ VA G V
Sbjct: 275 TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV-----QEPPHFVVKPRDQVVALGRTV 329
Query: 1028 RLECRVLGVPPPQIFWKKENE-------SLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
+C G P P IFW++E S+ R S+ Q L I + D G
Sbjct: 330 TFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQRSDVG 385
Query: 1081 WYTVSAKNEAGIVSCTARLDV 1101
+Y N AG + A L+V
Sbjct: 386 YYICQTLNVAGSIITKAYLEV 406
Score = 87.0 bits (214), Expect = 9e-17
Identities = 85/314 (27%), Positives = 121/314 (38%), Gaps = 60/314 (19%)
Query: 796 FTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAAN 855
F C G+P P + W KD ++ PKS Y I+ D +L T D G+YT +A N
Sbjct: 242 FKCEARGDPVPTVRWRKDDGEL-PKS-RYEIRDDH----TLKIRKVTAGDMGSYTCVAEN 295
Query: 856 PQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQ 915
G+ + L VQ EP PHF+
Sbjct: 296 MVGKAEASATLTVQ--------------------------------EP-------PHFVV 316
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP------VRPDSAHKMLVRENGVHSL 969
P D V G+ C+ +G P P + W+ +G P S+ + V + G L
Sbjct: 317 KPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DL 374
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK--LQNTGVADGYPV 1027
I V D G Y C N AG L V A +PP I + + T DG V
Sbjct: 375 TITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFV 434
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 1087
L C G P P I W+K+ ++ R+ ++ L I+ A D G YT A
Sbjct: 435 -LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTGRYTCIAS 489
Query: 1088 NEAGIVSCTARLDV 1101
+G + +A ++V
Sbjct: 490 TPSGEATWSAYIEV 503
Score = 85.1 bits (209), Expect = 3e-16
Identities = 59/198 (29%), Positives = 93/198 (46%), Gaps = 21/198 (10%)
Query: 904 IQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDS----AHKM 959
+++ F P ++ P DL V +G+ ++CK G PTP + W G+ V D +H+M
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 960 LVRENGVHSL-IIEPVTSR-DAGIYTCIATNRAGQ---NSFSLELVVAAKEAHKPPVFIE 1014
L+ + L I+ SR D G+Y C+A N G+ ++ SLE+ + + + P
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNP---- 137
Query: 1015 KLQNTGVADGYPVRLECR-VLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQG 1073
+ VA G P +EC+ G P P I WKK+ L +R+++ L+I
Sbjct: 138 --SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITY 190
Query: 1074 ATKEDAGWYTVSAKNEAG 1091
K DAG Y N G
Sbjct: 191 TRKSDAGKYVCVGTNMVG 208
Score = 65.9 bits (159), Expect = 2e-10
Identities = 85/352 (24%), Positives = 131/352 (37%), Gaps = 49/352 (13%)
Query: 282 VAEGSRVYLECRVT-GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
VA G +EC+ G+P P + W +G L + D +I GG L +I + D G
Sbjct: 142 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGKL---MITYTRKSDAG 197
Query: 341 RYTCLATNPSGS-DTTSAEV-------FIEGASS---TDSDSESLAFKSRAGAMPQAQKK 389
+Y C+ TN G ++ AE+ F++ S+ T DS ++R +P + +
Sbjct: 198 KYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR 257
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---------RPDGTTTAYFP 440
L PK+ L + SY C T T P
Sbjct: 258 KDDGEL------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEP 311
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA-- 498
P F + ++ VA G+ V +C G P + W R+GS+ + + P+S++
Sbjct: 312 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQ-----NLLFSYQPPQSSSRF 366
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTE-----------NCS 547
+ L I D G + C N GS + A L VT + N +
Sbjct: 367 SVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 426
Query: 548 YESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAAL 599
G P P IL L S + S I+Q+ N L + A L
Sbjct: 427 VAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 478
Score = 63.2 bits (152), Expect = 1e-09
Identities = 87/365 (23%), Positives = 132/365 (36%), Gaps = 49/365 (13%)
Query: 207 PKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQD----LAVPHNRKSHPQPH 262
P+ P +S SP++D+ E ++ Y D + V N +
Sbjct: 155 PRGHPEPTISWKKDGSPLDDKDE-RITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESE 213
Query: 263 SA-LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC 321
A L P F+++ + V +C G+P P VRW + EL +
Sbjct: 214 VAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-----RY 268
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEV--------FIEGASSTDSDSES 373
E D HTL I + D G YTC+A N G SA + ++ + +
Sbjct: 269 EIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRT 328
Query: 374 LAFKSRAGAMPQAQ---KKTTSVSLTIGSSSPKTGVTTAVIQ--PLSVPVQQVHSPTSYL 428
+ F+ A PQ ++ S +L P++ +V Q L++ Q Y+
Sbjct: 329 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 388
Query: 429 CRPDGT-----TTAYF----------PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQ 473
C+ T AY PPV + N VA VL C G+P +
Sbjct: 389 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 448
Query: 474 WFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATST 533
W R+ + + D RI Q E L I D G +TC A G AT +
Sbjct: 449 W-RKDGVLVSTQDSRIKQL---------ENGVLQIRYAKLGDTGRYTCIASTPSGEATWS 498
Query: 534 AQLVV 538
A + V
Sbjct: 499 AYIEV 503
Score = 62.0 bits (149), Expect = 3e-09
Identities = 64/229 (27%), Positives = 87/229 (37%), Gaps = 41/229 (17%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ---ISPKSDHYTIQRDLDGT 833
P F +K + + G VTF C GNP+P I+W ++G Q S + + + + T
Sbjct: 312 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 371
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR 893
L T D G Y N G I L V V + R P
Sbjct: 372 GDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDV----IADRPP------------ 415
Query: 894 SRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV-R 952
P Q P + TV + C +G P P + W+ DG V
Sbjct: 416 -----------------PVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVST 458
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
DS K L ENGV L I D G YTCIA+ +G+ ++S + V
Sbjct: 459 QDSRIKQL--ENGV--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEV 503
Score = 61.6 bits (148), Expect = 4e-09
Identities = 71/292 (24%), Positives = 102/292 (34%), Gaps = 36/292 (12%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD----IQIHCEGGDL 326
PR ++ V++G L C+ G PTP + W+ G+ + D ++ G L
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 327 HTLIIAEAFED--DTGRYTCLATNPSG---SDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
L I + D G Y C+A N G S S EV I + S+ +
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPA 148
Query: 382 AM----PQAQKKTTSVSLTIGSS-SPKTGVTTAVIQPLSVPVQQVHSPTSYLC------- 429
M P+ + T GS K T L + + Y+C
Sbjct: 149 VMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVG 208
Query: 430 ---RPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
T P F K N AV +C RG P V+W + E+
Sbjct: 209 ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL----- 263
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P+S E + TL I + D G +TC A N G A ++A L V
Sbjct: 264 -------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Score = 50.4 bits (119), Expect = 9e-06
Identities = 101/467 (21%), Positives = 173/467 (37%), Gaps = 115/467 (24%)
Query: 443 FTKELQNTAVAEGQVVVLECRV-RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
F + + VA G+ V+EC+ RG P + W + GS + D D RI + +
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGK------ 185
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATS-TAQLVVTS-----------ANTENCSYE 549
L+I T DAG + C N G S A+L V A T + S E
Sbjct: 186 ----LMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAE 241
Query: 550 SMGESNNDHFQHFPPPPPI--------LETSSLELASKKPSEIQQVNNPELGLSRAALQM 601
E+ D P P + L S E+ +I++V ++G +
Sbjct: 242 FKCEARGD------PVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAEN 295
Query: 602 QFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKA 661
GKA ++ +L +EPP + KP+
Sbjct: 296 MV---------------------GKAEASATLTV--------QEPPHFVVKPR------- 319
Query: 662 SRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVF 721
D V+ L R + F+ + N QP + + ++ LL F
Sbjct: 320 ----------------DQVVA-LGRTVTFQCEATGNPQPAIFWRREGSQNLL-------F 355
Query: 722 NIQEPEEETANQEYKVSSCEQRLI-----SEIEYRLERSPVDESGDEVQYGDVPVENGMA 776
+ Q P+ ++ + VS I S++ Y + ++ ++ +G + + V + +A
Sbjct: 356 SYQPPQ---SSSRFSVSQTGDLTITNVQRSDVGYYICQT-LNVAGSIITKAYLEVTDVIA 411
Query: 777 PFFEMKLKHYKIFEGMPVTFT----CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG 832
++ + + + V T C G+P P I W KDG +S + I++ +G
Sbjct: 412 DRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSR--IKQLENG 469
Query: 833 TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPR 879
L + L D G YT +A+ P G + + + VQ + PR
Sbjct: 470 V--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPR 514
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/85 (40%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI-HCEGGDLHTLIIAEAFED 337
+Q VA L C TG+P P + W +G L +T D +I E G L I A
Sbjct: 424 NQTVAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIKQLENGVLQ---IRYAKLG 479
Query: 338 DTGRYTCLATNPSGSDTTSAEVFIE 362
DTGRYTC+A+ PSG T SA + ++
Sbjct: 480 DTGRYTCIASTPSGEATWSAYIEVQ 504
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/110 (24%), Positives = 43/110 (39%), Gaps = 11/110 (10%)
Query: 428 LCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
LC FPP + + V++G+ L C+ G P ++W++ G ++ D
Sbjct: 16 LCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKD- 74
Query: 488 RILQKKPRS-----TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATS 532
PRS + +V D G++ C ARN G A S
Sbjct: 75 -----DPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVS 119
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 98.6 bits (244), Expect = 3e-20
Identities = 99/381 (25%), Positives = 147/381 (38%), Gaps = 81/381 (21%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTA-----ST 842
+ +G P T C+ G P P I W+K G+++ D R L + SL +
Sbjct: 79 VSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKS 138
Query: 843 LDDDGNYTIMAANPQGR-ISCTGRLMVQAVNQRGRSPRS----------------PSGHP 885
D+G Y +A N G +S L V + R S P GHP
Sbjct: 139 RPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHP 198
Query: 886 H--------------------VRRPR-----SRSRDSGD------------ENEPIQERF 908
+R + +R D+G E+E +
Sbjct: 199 EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTV 258
Query: 909 F-RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVH 967
RP F++ P +L V C+ G P P + W+ D + P S ++ +R++ H
Sbjct: 259 LERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL-PKSRYE--IRDD--H 313
Query: 968 SLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPV 1027
+L I VT+ D G YTC+A N G+ S L V +PP F+ K ++ VA G V
Sbjct: 314 TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV-----QEPPHFVVKPRDQVVALGRTV 368
Query: 1028 RLECRVLGVPPPQIFWKKENE-------SLTHSTDRVSMHQDNHGYICLLIQGATKEDAG 1080
+C G P P IFW++E S+ R S+ Q L I + D G
Sbjct: 369 TFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQRSDVG 424
Query: 1081 WYTVSAKNEAGIVSCTARLDV 1101
+Y N AG + A L+V
Sbjct: 425 YYICQTLNVAGSIITKAYLEV 445
Score = 87.0 bits (214), Expect = 9e-17
Identities = 85/314 (27%), Positives = 121/314 (38%), Gaps = 60/314 (19%)
Query: 796 FTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAAN 855
F C G+P P + W KD ++ PKS Y I+ D +L T D G+YT +A N
Sbjct: 281 FKCEARGDPVPTVRWRKDDGEL-PKS-RYEIRDDH----TLKIRKVTAGDMGSYTCVAEN 334
Query: 856 PQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQ 915
G+ + L VQ EP PHF+
Sbjct: 335 MVGKAEASATLTVQ--------------------------------EP-------PHFVV 355
Query: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKP------VRPDSAHKMLVRENGVHSL 969
P D V G+ C+ +G P P + W+ +G P S+ + V + G L
Sbjct: 356 KPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG--DL 413
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEK--LQNTGVADGYPV 1027
I V D G Y C N AG L V A +PP I + + T DG V
Sbjct: 414 TITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFV 473
Query: 1028 RLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAK 1087
L C G P P I W+K+ ++ R+ ++ L I+ A D G YT A
Sbjct: 474 -LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTGRYTCIAS 528
Query: 1088 NEAGIVSCTARLDV 1101
+G + +A ++V
Sbjct: 529 TPSGEATWSAYIEV 542
Score = 85.5 bits (210), Expect = 3e-16
Identities = 63/214 (29%), Positives = 99/214 (46%), Gaps = 23/214 (10%)
Query: 890 PRSRSRDS--GDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLD 947
P S + D+ G +++ F P ++ P DL V +G+ ++CK G PTP + W
Sbjct: 45 PTSDNDDNSLGYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKG 104
Query: 948 GKPVRPDS----AHKMLVRENGVHSL-IIEPVTSR-DAGIYTCIATNRAGQ---NSFSLE 998
G+ V D +H+ML+ + L I+ SR D G+Y C+A N G+ ++ SLE
Sbjct: 105 GERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLE 164
Query: 999 LVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECR-VLGVPPPQIFWKKENESLTHSTDRV 1057
+ + + + P + VA G P +EC+ G P P I WKK+ L +R+
Sbjct: 165 VAILRDDFRQNP------SDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERI 218
Query: 1058 SMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAG 1091
++ L+I K DAG Y N G
Sbjct: 219 TIRGGK-----LMITYTRKSDAGKYVCVGTNMVG 247
Score = 65.9 bits (159), Expect = 2e-10
Identities = 85/352 (24%), Positives = 131/352 (37%), Gaps = 49/352 (13%)
Query: 282 VAEGSRVYLECRVT-GNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTG 340
VA G +EC+ G+P P + W +G L + D +I GG L +I + D G
Sbjct: 181 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGKL---MITYTRKSDAG 236
Query: 341 RYTCLATNPSGS-DTTSAEV-------FIEGASS---TDSDSESLAFKSRAGAMPQAQKK 389
+Y C+ TN G ++ AE+ F++ S+ T DS ++R +P + +
Sbjct: 237 KYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR 296
Query: 390 TTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLC---------RPDGTTTAYFP 440
L PK+ L + SY C T T P
Sbjct: 297 KDDGEL------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEP 350
Query: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA-- 498
P F + ++ VA G+ V +C G P + W R+GS+ + + P+S++
Sbjct: 351 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQ-----NLLFSYQPPQSSSRF 405
Query: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTE-----------NCS 547
+ L I D G + C N GS + A L VT + N +
Sbjct: 406 SVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 465
Query: 548 YESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAAL 599
G P P IL L S + S I+Q+ N L + A L
Sbjct: 466 VAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 517
Score = 63.2 bits (152), Expect = 1e-09
Identities = 87/365 (23%), Positives = 132/365 (36%), Gaps = 49/365 (13%)
Query: 207 PKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQD----LAVPHNRKSHPQPH 262
P+ P +S SP++D+ E ++ Y D + V N +
Sbjct: 194 PRGHPEPTISWKKDGSPLDDKDE-RITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESE 252
Query: 263 SA-LHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC 321
A L P F+++ + V +C G+P P VRW + EL +
Sbjct: 253 VAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-----RY 307
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEV--------FIEGASSTDSDSES 373
E D HTL I + D G YTC+A N G SA + ++ + +
Sbjct: 308 EIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRT 367
Query: 374 LAFKSRAGAMPQAQ---KKTTSVSLTIGSSSPKTGVTTAVIQ--PLSVPVQQVHSPTSYL 428
+ F+ A PQ ++ S +L P++ +V Q L++ Q Y+
Sbjct: 368 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 427
Query: 429 CRPDGT-----TTAYF----------PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQ 473
C+ T AY PPV + N VA VL C G+P +
Sbjct: 428 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 487
Query: 474 WFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATST 533
W R+ + + D RI Q E L I D G +TC A G AT +
Sbjct: 488 W-RKDGVLVSTQDSRIKQL---------ENGVLQIRYAKLGDTGRYTCIASTPSGEATWS 537
Query: 534 AQLVV 538
A + V
Sbjct: 538 AYIEV 542
Score = 62.0 bits (149), Expect = 3e-09
Identities = 64/229 (27%), Positives = 87/229 (37%), Gaps = 41/229 (17%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQ---ISPKSDHYTIQRDLDGT 833
P F +K + + G VTF C GNP+P I+W ++G Q S + + + + T
Sbjct: 351 PHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 410
Query: 834 CSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSR 893
L T D G Y N G I L V V + R P
Sbjct: 411 GDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDV----IADRPP------------ 454
Query: 894 SRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPV-R 952
P Q P + TV + C +G P P + W+ DG V
Sbjct: 455 -----------------PVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVST 497
Query: 953 PDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV 1001
DS K L ENGV L I D G YTCIA+ +G+ ++S + V
Sbjct: 498 QDSRIKQL--ENGV--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEV 542
Score = 61.6 bits (148), Expect = 4e-09
Identities = 71/292 (24%), Positives = 102/292 (34%), Gaps = 36/292 (12%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD----IQIHCEGGDL 326
PR ++ V++G L C+ G PTP + W+ G+ + D ++ G L
Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 127
Query: 327 HTLIIAEAFED--DTGRYTCLATNPSG---SDTTSAEVFIEGASSTDSDSESLAFKSRAG 381
L I + D G Y C+A N G S S EV I + S+ +
Sbjct: 128 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPA 187
Query: 382 AM----PQAQKKTTSVSLTIGSS-SPKTGVTTAVIQPLSVPVQQVHSPTSYLC------- 429
M P+ + T GS K T L + + Y+C
Sbjct: 188 VMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVG 247
Query: 430 ---RPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPD 486
T P F K N AV +C RG P V+W + E+
Sbjct: 248 ERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL----- 302
Query: 487 FRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
P+S E + TL I + D G +TC A N G A ++A L V
Sbjct: 303 -------PKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347
Score = 50.4 bits (119), Expect = 9e-06
Identities = 101/467 (21%), Positives = 173/467 (37%), Gaps = 115/467 (24%)
Query: 443 FTKELQNTAVAEGQVVVLECRV-RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPE 501
F + + VA G+ V+EC+ RG P + W + GS + D D RI + +
Sbjct: 172 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDK-DERITIRGGK------ 224
Query: 502 EICTLVIAETFPEDAGIFTCSARNDYGSATS-TAQLVVTS-----------ANTENCSYE 549
L+I T DAG + C N G S A+L V A T + S E
Sbjct: 225 ----LMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAE 280
Query: 550 SMGESNNDHFQHFPPPPPI--------LETSSLELASKKPSEIQQVNNPELGLSRAALQM 601
E+ D P P + L S E+ +I++V ++G +
Sbjct: 281 FKCEARGD------PVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAEN 334
Query: 602 QFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLGFPKKA 661
GKA ++ +L +EPP + KP+
Sbjct: 335 MV---------------------GKAEASATLTV--------QEPPHFVVKPR------- 358
Query: 662 SRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVF 721
D V+ L R + F+ + N QP + + ++ LL F
Sbjct: 359 ----------------DQVVA-LGRTVTFQCEATGNPQPAIFWRREGSQNLL-------F 394
Query: 722 NIQEPEEETANQEYKVSSCEQRLI-----SEIEYRLERSPVDESGDEVQYGDVPVENGMA 776
+ Q P+ ++ + VS I S++ Y + ++ ++ +G + + V + +A
Sbjct: 395 SYQPPQ---SSSRFSVSQTGDLTITNVQRSDVGYYICQT-LNVAGSIITKAYLEVTDVIA 450
Query: 777 PFFEMKLKHYKIFEGMPVTFT----CRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDG 832
++ + + + V T C G+P P I W KDG +S + I++ +G
Sbjct: 451 DRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSR--IKQLENG 508
Query: 833 TCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPR 879
L + L D G YT +A+ P G + + + VQ + PR
Sbjct: 509 V--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPR 553
Score = 50.4 bits (119), Expect = 9e-06
Identities = 34/85 (40%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
Query: 279 SQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI-HCEGGDLHTLIIAEAFED 337
+Q VA L C TG+P P + W +G L +T D +I E G L I A
Sbjct: 463 NQTVAVDGTFVLSCVATGSPVPTILWRKDGV-LVSTQDSRIKQLENGVLQ---IRYAKLG 518
Query: 338 DTGRYTCLATNPSGSDTTSAEVFIE 362
DTGRYTC+A+ PSG T SA + ++
Sbjct: 519 DTGRYTCIASTPSGEATWSAYIEVQ 543
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 11/99 (11%)
Query: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRS-- 496
FPP + + V++G+ L C+ G P ++W++ G ++ D PRS
Sbjct: 66 FPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKD------DPRSHR 119
Query: 497 ---TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATS 532
+ +V D G++ C ARN G A S
Sbjct: 120 MLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVS 158
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 97.8 bits (242), Expect = 5e-20
Identities = 86/318 (27%), Positives = 120/318 (37%), Gaps = 59/318 (18%)
Query: 788 IFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDG 847
+ G V FTCR GNPKP+I W ++ ++S K+D D DGT + T T D G
Sbjct: 257 VTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLD-DGTLMIQNTQET--DQG 313
Query: 848 NYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER 907
Y MA N G + + + + R
Sbjct: 314 IYQCMAKNVAGEV---------------------------------------KTQEVTLR 334
Query: 908 FF----RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRE 963
+F RP F+ P + V G+ ++C +G P P +SW + P +
Sbjct: 335 YFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPS 394
Query: 964 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVAD 1023
G++ I+ V D+G Y C ATN + ++V A P F Q+ V +
Sbjct: 395 GGLY---IQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL-----PQFTVTPQDRVVIE 446
Query: 1024 GYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYT 1083
G V +C G PPP I W K L S DR + + L I G D G Y
Sbjct: 447 GQTVDFQCEAKGNPPPVIAWTKGGSQL--SVDRRHLVLSSG---TLRISGVALHDQGQYE 501
Query: 1084 VSAKNEAGIVSCTARLDV 1101
A N G A L V
Sbjct: 502 CQAVNIIGSQKVVAHLTV 519
Score = 88.6 bits (218), Expect = 3e-17
Identities = 84/327 (25%), Positives = 116/327 (35%), Gaps = 55/327 (16%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P F ++ ++ ++ G VT C G+P P+I W + + P I + L
Sbjct: 342 PTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITP----SGGL 397
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
+ D G Y A N + T ++VQA+
Sbjct: 398 YIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL------------------------- 432
Query: 897 SGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSA 956
P F P D V EG+ C+ G P P ++W G + D
Sbjct: 433 --------------PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRR 478
Query: 957 HKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKL 1016
H LV +G +L I V D G Y C A N G L V + PVF
Sbjct: 479 H--LVLSSG--TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTV---QPRVTPVFASIP 531
Query: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATK 1076
+T V G V+L C G P P I W K+ +T S H G+ L I
Sbjct: 532 SDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESG---KFHISPEGF--LTINDVGP 586
Query: 1077 EDAGWYTVSAKNEAGIVSCTARLDVYI 1103
DAG Y A+N G S + L V +
Sbjct: 587 ADAGRYECVARNTIGSASVSMVLSVNV 613
Score = 84.0 bits (206), Expect = 7e-16
Identities = 56/188 (29%), Positives = 87/188 (46%), Gaps = 7/188 (3%)
Query: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
RP P D V G C+ G P P++ W + + + ++ + ++G +L
Sbjct: 245 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG--TL 302
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRL 1029
+I+ D GIY C+A N AG+ + E+ + + P F+ + QNT V G V L
Sbjct: 303 MIQNTQETDQGIYQCMAKNVAGEVK-TQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTL 361
Query: 1030 ECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNE 1089
EC G PPP+I W + + + RV++ YI ++QG D+G Y SA N
Sbjct: 362 ECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQG----DSGEYACSATNN 417
Query: 1090 AGIVSCTA 1097
V TA
Sbjct: 418 IDSVHATA 425
Score = 82.4 bits (202), Expect = 2e-15
Identities = 80/293 (27%), Positives = 117/293 (39%), Gaps = 42/293 (14%)
Query: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWF-CEGKELHNTPDIQIHCEGGDL 326
PA P F+ + ++ EV G V LEC TG+P PR+ W + L P + I GG
Sbjct: 339 PARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG-- 396
Query: 327 HTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGA---SSTDSD-----SESLAFKS 378
L I + D+G Y C ATN S +A + ++ + T D +++ F+
Sbjct: 397 --LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQC 454
Query: 379 RAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQV--HSPTSYLCRPDG--- 433
A P ++ T G S V+ ++ + V H Y C+
Sbjct: 455 EAKGNP-----PPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIG 509
Query: 434 --------TTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSP 485
T PVF +T V G V L C +G P + W + G ++ +S
Sbjct: 510 SQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESG 569
Query: 486 DFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
F I PE L I + P DAG + C ARN GSA+ + L V
Sbjct: 570 KFHI---------SPEGF--LTINDVGPADAGRYECVARNTIGSASVSMVLSV 611
Score = 77.0 bits (188), Expect = 9e-14
Identities = 76/291 (26%), Positives = 110/291 (37%), Gaps = 40/291 (13%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
PR + + +V G+ VY CR GNP P + W EL D +++ D TL+
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLL--DDGTLM 303
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTT-----------SAEVFIEGASSTD-SDSESLAFKS 378
I E D G Y C+A N +G T + F+ +T+ ES+ +
Sbjct: 304 IQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLEC 363
Query: 379 RAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTS--YLCRPDGT-- 434
A P + T T P+ +T + + +Q V S Y C
Sbjct: 364 SATGHPPPRISWTRGDRTPLPVDPRVNITPSG----GLYIQNVVQGDSGEYACSATNNID 419
Query: 435 ---TTAYF----PPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDF 487
TA+ P FT Q+ V EGQ V +C +G PP + W + GS++
Sbjct: 420 SVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRH 479
Query: 488 RILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
+L TL I+ D G + C A N GS A L V
Sbjct: 480 LVLSSG-----------TLRISGVALHDQGQYECQAVNIIGSQKVVAHLTV 519
Score = 42.0 bits (97), Expect = 0.003
Identities = 28/95 (29%), Positives = 38/95 (40%), Gaps = 4/95 (4%)
Query: 262 HSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHC 321
H + P F V G+ V L C G P P + W +G ++ + I
Sbjct: 516 HLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISP 575
Query: 322 EGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTS 356
EG L I + D GRY C+A N GS + S
Sbjct: 576 EG----FLTINDVGPADAGRYECVARNTIGSASVS 606
Score = 33.9 bits (76), Expect = 0.88
Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 8/120 (6%)
Query: 753 ERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFK 812
E V+ G + + V+ + P F + G V C G P+P I W K
Sbjct: 501 ECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNK 560
Query: 813 DGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVN 872
DG Q++ + +G +++ D G Y +A N G S + MV +VN
Sbjct: 561 DGVQVTESGKFHI---SPEGFLTINDVGPA--DAGRYECVARNTIGSASVS---MVLSVN 612
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 97.8 bits (242), Expect = 5e-20
Identities = 88/313 (28%), Positives = 122/313 (38%), Gaps = 59/313 (18%)
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
+G V C GNP P I W K I K+ R L LDD G Y
Sbjct: 314 KGTTVKMECFALGNPVPTITWMKVNGYIPSKA------RLRKSQAVLEIPNVQLDDAGIY 367
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 909
A N +G+ S G+L V +
Sbjct: 368 ECRAENSRGKNSFRGQLQV---------------------------------------YT 388
Query: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
PH+++ D + G R +CK +G P P W +G P+ P S +M+ NGV L
Sbjct: 389 YPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV---NGV--L 443
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT-GVADGYPVR 1028
+I V DAG+Y C+A N+ G S EL + A P + +L+ T V V
Sbjct: 444 MIHNVNQSDAGMYQCLAENKYGAIYASAELKILAS---APTFALNQLKKTIIVTKDQEVV 500
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
+EC+ G P P I WKK + ++ R+++ D L I A+K D G Y +N
Sbjct: 501 IECKPQGSPKPTISWKKGDRAV-RENKRIAILPDG----SLRILNASKSDEGKYVCRGEN 555
Query: 1089 EAGIVSCTARLDV 1101
G A L V
Sbjct: 556 VFGSAEIIASLSV 568
Score = 80.1 bits (196), Expect = 1e-14
Identities = 60/188 (31%), Positives = 87/188 (46%), Gaps = 16/188 (8%)
Query: 917 PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTS 976
P +T +G +M+C G P P ++W + P A L + V L I V
Sbjct: 307 PFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYI-PSKAR--LRKSQAV--LEIPNVQL 361
Query: 977 RDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGV 1036
DAGIY C A N G+NSF +L + + P ++EKL +T + G P+R EC+ G
Sbjct: 362 DDAGIYECRAENSRGKNSFRGQL-----QVYTYPHWVEKLNDTQLDSGSPLRWECKATGK 416
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
P P W K L+ + RV M L+I + DAG Y A+N+ G + +
Sbjct: 417 PRPTYRWLKNGVPLSPQS-RVEMVNG-----VLMIHNVNQSDAGMYQCLAENKYGAIYAS 470
Query: 1097 ARLDVYIS 1104
A L + S
Sbjct: 471 AELKILAS 478
Score = 63.5 bits (153), Expect = 1e-09
Identities = 71/288 (24%), Positives = 97/288 (33%), Gaps = 47/288 (16%)
Query: 283 AEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE-DDTGR 341
++ +V L C V GNP P RW G E+ D + G T II+ E D+G
Sbjct: 114 SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDG---TFIISNPSEAKDSGH 170
Query: 342 YTCLATNPSGS------------------DTTSAEVFIEGAS-----STDSDSESLAFKS 378
Y CLATN GS T SA EG S S + +
Sbjct: 171 YQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSW 230
Query: 379 RAGAMPQ--AQKKTTSVSLTIGS------SSPKTGVTTAVIQPLSVPVQQVHSPTSYLCR 430
P A+ +S G+ + G +++ + + PT R
Sbjct: 231 VFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLR 290
Query: 431 PDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
DG Y P + A+G V +EC G P + W + I R
Sbjct: 291 NDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKS 350
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Q L I +DAGI+ C A N G + QL V
Sbjct: 351 Q------------AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV 386
Score = 60.5 bits (145), Expect = 9e-09
Identities = 84/324 (25%), Positives = 128/324 (39%), Gaps = 62/324 (19%)
Query: 794 VTFTCRVAGNPKPKIYWFKDGKQISPKSDH-YTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
V C V GNP P W ++G +I +SD+ Y++ +DGT + + S D G+Y +
Sbjct: 119 VALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSL---IDGTFII-SNPSEAKDSGHYQCL 174
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A N G I L +A Q ++ R+R +
Sbjct: 175 ATNTVGSI-----LSREATLQ----------FAYLGNFSGRTRSA--------------- 204
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDGKP--VRPDSAHKMLVRENGVHS 968
++V+EG+ + C +P++ SW + P V DS + + +E G +
Sbjct: 205 -------VSVREGQGVVLMCSPPP-HSPEIIYSWVFNEFPSFVAEDS-RRFISQETG--N 253
Query: 969 LIIEPVTSRDAGIYTCIATN---RAGQNSFSLELVV---AAKEAHKPPVFIEKLQNTGVA 1022
L I V + D G Y C+ N A S L + ++P + + A
Sbjct: 254 LYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAA 313
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
G V++EC LG P P I W K N + S R+ Q L I +DAG Y
Sbjct: 314 KGTTVKMECFALGNPVPTITWMKVNGYIP-SKARLRKSQ-----AVLEIPNVQLDDAGIY 367
Query: 1083 TVSAKNEAGIVSCTARLDVYISRH 1106
A+N G S +L VY H
Sbjct: 368 ECRAENSRGKNSFRGQLQVYTYPH 391
Score = 59.3 bits (142), Expect = 2e-08
Identities = 67/288 (23%), Positives = 112/288 (38%), Gaps = 30/288 (10%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P +++KL ++ GS + EC+ TG P P RW G L +P ++ G L+
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL--SPQSRVEMVNG---VLM 444
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE----SLAFKSRAGAM--- 383
I + D G Y CLA N G+ SAE+ I ++ T + ++ + K + +
Sbjct: 445 IHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECK 504
Query: 384 PQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT--SYLCRPD--------- 432
PQ K T +S G + + A++ S+ + Y+CR +
Sbjct: 505 PQGSPKPT-ISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEII 563
Query: 433 GTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQV--QWFRQGSEIQDSPDFRIL 490
+ + P + T + G+ +VL C+ L V W +G I DF
Sbjct: 564 ASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPI----DFEEE 619
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
S L+I AG + C + S + A+L+V
Sbjct: 620 GGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLV 667
Score = 56.6 bits (135), Expect = 1e-07
Identities = 56/260 (21%), Positives = 97/260 (37%), Gaps = 55/260 (21%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P + KL ++ G P+ + C+ G P+P W K+G +SP+S + +G +
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV----NGVLMI 445
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
H + D G Y +A N G I + L + A
Sbjct: 446 HNVNQS--DAGMYQCLAENKYGAIYASAELKILA-------------------------- 477
Query: 897 SGDENEPIQERFFRPHFL--QAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
P F Q + V + + ++CK G P P +SW+ + VR +
Sbjct: 478 ------------SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVREN 525
Query: 955 SAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIE 1014
++ + +G SL I + D G Y C G+N F ++A+ +P
Sbjct: 526 K--RIAILPDG--SLRILNASKSDEGKYVC-----RGENVFGSAEIIASLSVKEPTRIEL 576
Query: 1015 KLQNTGVADGYPVRLECRVL 1034
+ T + G + L C+ +
Sbjct: 577 TPKRTELTVGESIVLNCKAI 596
Score = 53.5 bits (127), Expect = 1e-06
Identities = 66/299 (22%), Positives = 112/299 (37%), Gaps = 49/299 (16%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
+P +HFP + A+G+ V +EC GNP P + W + + ++
Sbjct: 299 EPKIEVHFPF---------TVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLR- 348
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEV-------FIEGASSTDSDSE 372
L I DD G Y C A N G ++ ++ ++E + T DS
Sbjct: 349 ----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSG 404
Query: 373 S-LAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRP 431
S L ++ +A P+ + + + SP++ V V L + Y C
Sbjct: 405 SPLRWECKATGKPRPTYRWLKNGVPL---SPQSRV-EMVNGVLMIHNVNQSDAGMYQCLA 460
Query: 432 DGTTTAYF-----------PPVFTKELQNT-AVAEGQVVVLECRVRGAPPLQVQWFRQGS 479
+ A + P +L+ T V + Q VV+EC+ +G+P + W +
Sbjct: 461 ENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDR 520
Query: 480 EIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++++ IL +L I D G + C N +GSA A L V
Sbjct: 521 AVRENKRIAILPDG-----------SLRILNASKSDEGKYVCRGENVFGSAEIIASLSV 568
Score = 46.6 bits (109), Expect = 1e-04
Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 8/101 (7%)
Query: 894 SRDSGDENEPIQERFFRPHFLQAPGDL---TVQEGKLCRMDCKVSGLPTPDLSWQLDGKP 950
S D+ ++E + + P F+Q P D+ T + K ++C+V G P P W +G
Sbjct: 85 SSDAFKQDESVD---YGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTE 141
Query: 951 VRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAG 991
+ +S ++ + + +I P ++D+G Y C+ATN G
Sbjct: 142 IDLESDYRYSLIDGTF--IISNPSEAKDSGHYQCLATNTVG 180
Score = 45.8 bits (107), Expect = 2e-04
Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 22/140 (15%)
Query: 414 LSVPVQQVHSPTSYLCRPD---------GTTTAYFPPVFTKELQNTAVAEGQVVVLECRV 464
L +P Q+ Y CR + G Y P + ++L +T + G + EC+
Sbjct: 354 LEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKA 413
Query: 465 RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSAR 524
G P +W + G + SP R+ L+I DAG++ C A
Sbjct: 414 TGKPRPTYRWLKNGVPL--SPQSRVEMVNG----------VLMIHNVNQSDAGMYQCLAE 461
Query: 525 NDYGSATSTAQL-VVTSANT 543
N YG+ ++A+L ++ SA T
Sbjct: 462 NKYGAIYASAELKILASAPT 481
Score = 42.7 bits (99), Expect = 0.002
Identities = 50/175 (28%), Positives = 71/175 (40%), Gaps = 24/175 (13%)
Query: 371 SESLAFKSRAGAMPQAQKKTTSVSLTIGS------SSPKTGVTTAVIQPLSVPVQQVHSP 424
S+SL S + A KK++S SL GS SSP G +A Q +SP
Sbjct: 21 SKSLPGLSTSYAALLRIKKSSSSSL-FGSKTRPRYSSPSLGTLSASSPSWLGAAQNYYSP 79
Query: 425 TSYLCRPDG---TTTAYFPPVFTKELQNTAV---AEGQVVVLECRVRGAPPLQVQWFRQG 478
+ D + + PVF +E + ++ + V L C VRG P +W R G
Sbjct: 80 INLYHSSDAFKQDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNG 139
Query: 479 SEIQDSPDFRI-LQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATS 532
+EI D+R L + P E +D+G + C A N GS S
Sbjct: 140 TEIDLESDYRYSLIDGTFIISNPSE----------AKDSGHYQCLATNTVGSILS 184
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 97.8 bits (242), Expect = 5e-20
Identities = 88/313 (28%), Positives = 122/313 (38%), Gaps = 59/313 (18%)
Query: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
+G V C GNP P I W K I K+ R L LDD G Y
Sbjct: 240 KGTTVKMECFALGNPVPTITWMKVNGYIPSKA------RLRKSQAVLEIPNVQLDDAGIY 293
Query: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 909
A N +G+ S G+L V +
Sbjct: 294 ECRAENSRGKNSFRGQLQV---------------------------------------YT 314
Query: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
PH+++ D + G R +CK +G P P W +G P+ P S +M+ NGV L
Sbjct: 315 YPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV---NGV--L 369
Query: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNT-GVADGYPVR 1028
+I V DAG+Y C+A N+ G S EL + A P + +L+ T V V
Sbjct: 370 MIHNVNQSDAGMYQCLAENKYGAIYASAELKILAS---APTFALNQLKKTIIVTKDQEVV 426
Query: 1029 LECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKN 1088
+EC+ G P P I WKK + ++ R+++ D L I A+K D G Y +N
Sbjct: 427 IECKPQGSPKPTISWKKGDRAV-RENKRIAILPDG----SLRILNASKSDEGKYVCRGEN 481
Query: 1089 EAGIVSCTARLDV 1101
G A L V
Sbjct: 482 VFGSAEIIASLSV 494
Score = 80.1 bits (196), Expect = 1e-14
Identities = 60/188 (31%), Positives = 87/188 (46%), Gaps = 16/188 (8%)
Query: 917 PGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTS 976
P +T +G +M+C G P P ++W + P A L + V L I V
Sbjct: 233 PFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYI-PSKAR--LRKSQAV--LEIPNVQL 287
Query: 977 RDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGV 1036
DAGIY C A N G+NSF +L + + P ++EKL +T + G P+R EC+ G
Sbjct: 288 DDAGIYECRAENSRGKNSFRGQL-----QVYTYPHWVEKLNDTQLDSGSPLRWECKATGK 342
Query: 1037 PPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCT 1096
P P W K L+ + RV M L+I + DAG Y A+N+ G + +
Sbjct: 343 PRPTYRWLKNGVPLSPQS-RVEMVNG-----VLMIHNVNQSDAGMYQCLAENKYGAIYAS 396
Query: 1097 ARLDVYIS 1104
A L + S
Sbjct: 397 AELKILAS 404
Score = 63.5 bits (153), Expect = 1e-09
Identities = 71/288 (24%), Positives = 97/288 (33%), Gaps = 47/288 (16%)
Query: 283 AEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFE-DDTGR 341
++ +V L C V GNP P RW G E+ D + G T II+ E D+G
Sbjct: 40 SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDG---TFIISNPSEAKDSGH 96
Query: 342 YTCLATNPSGS------------------DTTSAEVFIEGAS-----STDSDSESLAFKS 378
Y CLATN GS T SA EG S S + +
Sbjct: 97 YQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSW 156
Query: 379 RAGAMPQ--AQKKTTSVSLTIGS------SSPKTGVTTAVIQPLSVPVQQVHSPTSYLCR 430
P A+ +S G+ + G +++ + + PT R
Sbjct: 157 VFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLR 216
Query: 431 PDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRIL 490
DG Y P + A+G V +EC G P + W + I R
Sbjct: 217 NDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKS 276
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Q L I +DAGI+ C A N G + QL V
Sbjct: 277 Q------------AVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQV 312
Score = 60.5 bits (145), Expect = 9e-09
Identities = 84/324 (25%), Positives = 128/324 (39%), Gaps = 62/324 (19%)
Query: 794 VTFTCRVAGNPKPKIYWFKDGKQISPKSDH-YTIQRDLDGTCSLHTTASTLDDDGNYTIM 852
V C V GNP P W ++G +I +SD+ Y++ +DGT + + S D G+Y +
Sbjct: 45 VALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSL---IDGTFII-SNPSEAKDSGHYQCL 100
Query: 853 AANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPH 912
A N G I L +A Q ++ R+R +
Sbjct: 101 ATNTVGSI-----LSREATLQ----------FAYLGNFSGRTRSA--------------- 130
Query: 913 FLQAPGDLTVQEGKLCRMDCKVSGLPTPDL--SWQLDGKP--VRPDSAHKMLVRENGVHS 968
++V+EG+ + C +P++ SW + P V DS + + +E G +
Sbjct: 131 -------VSVREGQGVVLMCSPPP-HSPEIIYSWVFNEFPSFVAEDS-RRFISQETG--N 179
Query: 969 LIIEPVTSRDAGIYTCIATN---RAGQNSFSLELVV---AAKEAHKPPVFIEKLQNTGVA 1022
L I V + D G Y C+ N A S L + ++P + + A
Sbjct: 180 LYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAA 239
Query: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
G V++EC LG P P I W K N + S R+ Q L I +DAG Y
Sbjct: 240 KGTTVKMECFALGNPVPTITWMKVNGYIP-SKARLRKSQ-----AVLEIPNVQLDDAGIY 293
Query: 1083 TVSAKNEAGIVSCTARLDVYISRH 1106
A+N G S +L VY H
Sbjct: 294 ECRAENSRGKNSFRGQLQVYTYPH 317
Score = 59.3 bits (142), Expect = 2e-08
Identities = 67/288 (23%), Positives = 112/288 (38%), Gaps = 30/288 (10%)
Query: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
P +++KL ++ GS + EC+ TG P P RW G L +P ++ G L+
Sbjct: 316 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPL--SPQSRVEMVNG---VLM 370
Query: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE----SLAFKSRAGAM--- 383
I + D G Y CLA N G+ SAE+ I ++ T + ++ + K + +
Sbjct: 371 IHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECK 430
Query: 384 PQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPT--SYLCRPD--------- 432
PQ K T +S G + + A++ S+ + Y+CR +
Sbjct: 431 PQGSPKPT-ISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEII 489
Query: 433 GTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQV--QWFRQGSEIQDSPDFRIL 490
+ + P + T + G+ +VL C+ L V W +G I DF
Sbjct: 490 ASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPI----DFEEE 545
Query: 491 QKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
S L+I AG + C + S + A+L+V
Sbjct: 546 GGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLV 593
Score = 56.6 bits (135), Expect = 1e-07
Identities = 56/260 (21%), Positives = 97/260 (37%), Gaps = 55/260 (21%)
Query: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
P + KL ++ G P+ + C+ G P+P W K+G +SP+S + +G +
Sbjct: 316 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMV----NGVLMI 371
Query: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRD 896
H + D G Y +A N G I + L + A
Sbjct: 372 HNVNQS--DAGMYQCLAENKYGAIYASAELKILA-------------------------- 403
Query: 897 SGDENEPIQERFFRPHFL--QAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPD 954
P F Q + V + + ++CK G P P +SW+ + VR +
Sbjct: 404 ------------SAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVREN 451
Query: 955 SAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIE 1014
++ + +G SL I + D G Y C G+N F ++A+ +P
Sbjct: 452 K--RIAILPDG--SLRILNASKSDEGKYVC-----RGENVFGSAEIIASLSVKEPTRIEL 502
Query: 1015 KLQNTGVADGYPVRLECRVL 1034
+ T + G + L C+ +
Sbjct: 503 TPKRTELTVGESIVLNCKAI 522
Score = 53.5 bits (127), Expect = 1e-06
Identities = 66/299 (22%), Positives = 112/299 (37%), Gaps = 49/299 (16%)
Query: 260 QPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQI 319
+P +HFP + A+G+ V +EC GNP P + W + + ++
Sbjct: 225 EPKIEVHFPF---------TVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLR- 274
Query: 320 HCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEV-------FIEGASSTDSDSE 372
L I DD G Y C A N G ++ ++ ++E + T DS
Sbjct: 275 ----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSG 330
Query: 373 S-LAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRP 431
S L ++ +A P+ + + + SP++ V V L + Y C
Sbjct: 331 SPLRWECKATGKPRPTYRWLKNGVPL---SPQSRV-EMVNGVLMIHNVNQSDAGMYQCLA 386
Query: 432 DGTTTAYF-----------PPVFTKELQNT-AVAEGQVVVLECRVRGAPPLQVQWFRQGS 479
+ A + P +L+ T V + Q VV+EC+ +G+P + W +
Sbjct: 387 ENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDR 446
Query: 480 EIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
++++ IL +L I D G + C N +GSA A L V
Sbjct: 447 AVRENKRIAILPDG-----------SLRILNASKSDEGKYVCRGENVFGSAEIIASLSV 494
Score = 45.8 bits (107), Expect = 2e-04
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 5/86 (5%)
Query: 909 FRPHFLQAPGDL---TVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENG 965
+ P F+Q P D+ T + K ++C+V G P P W +G + +S ++ + +
Sbjct: 23 YGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGT 82
Query: 966 VHSLIIEPVTSRDAGIYTCIATNRAG 991
+I P ++D+G Y C+ATN G
Sbjct: 83 F--IISNPSEAKDSGHYQCLATNTVG 106
Score = 45.8 bits (107), Expect = 2e-04
Identities = 36/140 (25%), Positives = 59/140 (42%), Gaps = 22/140 (15%)
Query: 414 LSVPVQQVHSPTSYLCRPD---------GTTTAYFPPVFTKELQNTAVAEGQVVVLECRV 464
L +P Q+ Y CR + G Y P + ++L +T + G + EC+
Sbjct: 280 LEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKA 339
Query: 465 RGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSAR 524
G P +W + G + SP R+ L+I DAG++ C A
Sbjct: 340 TGKPRPTYRWLKNGVPL--SPQSRVEMVNG----------VLMIHNVNQSDAGMYQCLAE 387
Query: 525 NDYGSATSTAQL-VVTSANT 543
N YG+ ++A+L ++ SA T
Sbjct: 388 NKYGAIYASAELKILASAPT 407
Score = 37.7 bits (86), Expect = 0.061
Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 14/98 (14%)
Query: 439 FPPVFTKELQNTAV---AEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRI-LQKKP 494
+ PVF +E + ++ + V L C VRG P +W R G+EI D+R L
Sbjct: 23 YGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGT 82
Query: 495 RSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATS 532
+ P E +D+G + C A N GS S
Sbjct: 83 FIISNPSE----------AKDSGHYQCLATNTVGSILS 110
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,138,984
Number of Sequences: 37866
Number of extensions: 2485251
Number of successful extensions: 18009
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 242
Number of HSP's successfully gapped in prelim test: 341
Number of HSP's that attempted gapping in prelim test: 7718
Number of HSP's gapped (non-prelim): 6259
length of query: 1106
length of database: 18,247,518
effective HSP length: 113
effective length of query: 993
effective length of database: 13,968,660
effective search space: 13870879380
effective search space used: 13870879380
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.