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Search of human proteins with 91992160
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens]
(1429 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens] 2855 0.0
gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens] 2841 0.0
gi|4557757 MutL protein homolog 1 [Homo sapiens] 110 7e-24
gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens] 103 2e-21
gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens] 103 2e-21
gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens] 93 2e-18
gi|4505913 PMS2 postmeiotic segregation increased 2 isoform a [H... 83 2e-15
gi|239743246 PREDICTED: hypothetical protein XP_002342778 [Homo ... 58 6e-08
gi|169170512 PREDICTED: similar to Postmeiotic segregation incre... 58 6e-08
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 47 2e-04
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 47 2e-04
gi|113722133 senataxin [Homo sapiens] 40 0.012
gi|157388975 coiled-coil domain containing 99 [Homo sapiens] 40 0.016
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 37 0.10
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 37 0.10
gi|158534059 formin binding protein 4 [Homo sapiens] 37 0.10
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 36 0.23
gi|216548091 leucine zipper protein 1 [Homo sapiens] 36 0.23
gi|216548085 leucine zipper protein 1 [Homo sapiens] 36 0.23
gi|39995071 exonuclease 1 isoform b [Homo sapiens] 35 0.68
gi|39995069 exonuclease 1 isoform a [Homo sapiens] 35 0.68
gi|18491016 exonuclease 1 isoform b [Homo sapiens] 35 0.68
gi|14249456 zinc finger protein 514 [Homo sapiens] 34 0.88
gi|50083293 coiled-coil domain containing 123 [Homo sapiens] 34 0.88
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 34 1.2
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 34 1.2
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 34 1.2
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 34 1.2
gi|37595553 ring finger protein 111 [Homo sapiens] 34 1.2
gi|229577185 epidermal growth factor receptor pathway substrate ... 33 2.0
>gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens]
Length = 1429
Score = 2855 bits (7401), Expect = 0.0
Identities = 1429/1429 (100%), Positives = 1429/1429 (100%)
Query: 1 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG 60
MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
Sbjct: 1 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG 60
Query: 61 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF 120
MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
Sbjct: 61 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF 120
Query: 121 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL 180
VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
Sbjct: 121 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL 180
Query: 181 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS 240
MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
Sbjct: 181 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS 240
Query: 241 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP 300
SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
Sbjct: 241 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP 300
Query: 301 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE 360
ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
Sbjct: 301 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE 360
Query: 361 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV 420
DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
Sbjct: 361 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV 420
Query: 421 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE 480
NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
Sbjct: 421 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE 480
Query: 481 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN 540
AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
Sbjct: 481 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN 540
Query: 541 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR 600
ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
Sbjct: 541 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR 600
Query: 601 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS 660
VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
Sbjct: 601 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS 660
Query: 661 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY 720
TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
Sbjct: 661 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY 720
Query: 721 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT 780
RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
Sbjct: 721 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT 780
Query: 781 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE 840
NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE
Sbjct: 781 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE 840
Query: 841 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP 900
QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
Sbjct: 841 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP 900
Query: 901 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT 960
NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
Sbjct: 901 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT 960
Query: 961 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC 1020
ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
Sbjct: 961 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC 1020
Query: 1021 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK 1080
FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
Sbjct: 1021 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK 1080
Query: 1081 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS 1140
DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
Sbjct: 1081 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS 1140
Query: 1141 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI 1200
LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
Sbjct: 1141 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI 1200
Query: 1201 ACLMSTKTEENGEADSYEKQQAQGSGRKKLLSSTLIPPLEITVTEEQRRLLWCYHKNLED 1260
ACLMSTKTEENGEADSYEKQQAQGSGRKKLLSSTLIPPLEITVTEEQRRLLWCYHKNLED
Sbjct: 1201 ACLMSTKTEENGEADSYEKQQAQGSGRKKLLSSTLIPPLEITVTEEQRRLLWCYHKNLED 1260
Query: 1261 LGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGRSTVTKSIVEEFIREQLELLQTTGG 1320
LGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGRSTVTKSIVEEFIREQLELLQTTGG
Sbjct: 1261 LGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGRSTVTKSIVEEFIREQLELLQTTGG 1320
Query: 1321 IQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRLIEALSSCQLPFQCAHGRPSMLPLA 1380
IQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRLIEALSSCQLPFQCAHGRPSMLPLA
Sbjct: 1321 IQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRLIEALSSCQLPFQCAHGRPSMLPLA 1380
Query: 1381 DIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTRQSLQQSMPPCEPP 1429
DIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTRQSLQQSMPPCEPP
Sbjct: 1381 DIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTRQSLQQSMPPCEPP 1429
>gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]
Length = 1453
Score = 2841 bits (7366), Expect = 0.0
Identities = 1429/1453 (98%), Positives = 1429/1453 (98%), Gaps = 24/1453 (1%)
Query: 1 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG 60
MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG
Sbjct: 1 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQVQVIDNGFG 60
Query: 61 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF 120
MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF
Sbjct: 61 MGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTF 120
Query: 121 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL 180
VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL
Sbjct: 121 VKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCMDPRLEFEKVRQRIEALSL 180
Query: 181 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS 240
MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS
Sbjct: 181 MHPSISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYIS 240
Query: 241 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP 300
SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP
Sbjct: 241 SEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHRSTP 300
Query: 301 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE 360
ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE
Sbjct: 301 ELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVELSGE 360
Query: 361 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV 420
DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV
Sbjct: 361 DIKEFSEDNGFSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRKTTAENV 420
Query: 421 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE 480
NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE
Sbjct: 421 NTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLEQETIVASE 480
Query: 481 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN 540
AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN
Sbjct: 481 AGENEKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTVNGMAAN 540
Query: 541 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR 600
ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR
Sbjct: 541 ILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKKESSNCGRRNVFSYGR 600
Query: 601 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS 660
VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS
Sbjct: 601 VKLCSTGFITHVVQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLAS 660
Query: 661 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY 720
TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY
Sbjct: 661 TLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWY 720
Query: 721 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT 780
RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT
Sbjct: 721 RHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTT 780
Query: 781 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE 840
NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE
Sbjct: 781 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLE 840
Query: 841 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP 900
QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP
Sbjct: 841 QQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELP 900
Query: 901 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT 960
NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT
Sbjct: 901 NSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTT 960
Query: 961 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC 1020
ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC
Sbjct: 961 ENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGIC 1020
Query: 1021 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK 1080
FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK
Sbjct: 1021 FQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLSTFIAPTEDIQAACTK 1080
Query: 1081 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS 1140
DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS
Sbjct: 1081 DLTTVAVDVVLENGSQYRCQPFRSDLVLPFLPRARAERTVMRQDNRDTVDDTVSSESLQS 1140
Query: 1141 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI 1200
LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI
Sbjct: 1141 LFSEWDNPVFARYPEVAVDVSSGQAESLAVKIHNILYPYRFTKGMIHSMQVLQQVDNKFI 1200
Query: 1201 ACLMSTKTEENGEA------------------------DSYEKQQAQGSGRKKLLSSTLI 1236
ACLMSTKTEENGEA DSYEKQQAQGSGRKKLLSSTLI
Sbjct: 1201 ACLMSTKTEENGEAGGNLLVLVDQHAAHERIRLEQLIIDSYEKQQAQGSGRKKLLSSTLI 1260
Query: 1237 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR 1296
PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR
Sbjct: 1261 PPLEITVTEEQRRLLWCYHKNLEDLGLEFVFPDTSDSLVLVGKVPLCFVEREANELRRGR 1320
Query: 1297 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL 1356
STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL
Sbjct: 1321 STVTKSIVEEFIREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRL 1380
Query: 1357 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR 1416
IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR
Sbjct: 1381 IEALSSCQLPFQCAHGRPSMLPLADIDHLEQEKQIKPNLTKLRKMAQAWRLFGKAECDTR 1440
Query: 1417 QSLQQSMPPCEPP 1429
QSLQQSMPPCEPP
Sbjct: 1441 QSLQQSMPPCEPP 1453
>gi|4557757 MutL protein homolog 1 [Homo sapiens]
Length = 756
Score = 110 bits (276), Expect = 7e-24
Identities = 105/351 (29%), Positives = 174/351 (49%), Gaps = 32/351 (9%)
Query: 1 MIKCLSVEVQAKLRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQ-VQVIDNGF 59
+I+ L V ++ +G I ++E+ N +DA++ + V V + +Q+ DNG
Sbjct: 7 VIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGT 66
Query: 60 GMGSDDVEKVGNRYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKT 119
G+ +D++ V R+ TSK S +DL + YGFRGEALA+I+ +A V I++K
Sbjct: 67 GIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAH-VTITTKTADGKCA 125
Query: 120 FVKLFQSGKALKACEADVTRASAGTTVTVYNLFYQLPVRRKCM-DPRLEFEKVRQRIEAL 178
+ + GK LKA + GT +TV +LFY + RRK + +P E+ K+ + +
Sbjct: 126 YRASYSDGK-LKA-PPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRY 183
Query: 179 SLMHPSISFSLRND-VSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYK--EFEL 235
S+ + ISFS++ + + V LP V I+G S++L EI + K F++
Sbjct: 184 SVHNAGISFSVKKQGETVADVRTLPNASTV-DNIRSIFGNAVSRELIEIGCEDKTLAFKM 242
Query: 236 SGYISSEAHYNKNMQF-LFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSL 294
+GYIS+ + K F LF+N RLV T L K I+ + PKN
Sbjct: 243 NGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVY----AAYLPKN----------- 287
Query: 295 RHRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVK 345
+ P LY I+ Q DV + P K + F + +++L +Q+ ++
Sbjct: 288 ---THPFLYLSLEISPQ----NVDVNVHPTKHEVHFLHEESILERVQQHIE 331
>gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]
Length = 770
Score = 103 bits (256), Expect = 2e-21
Identities = 133/567 (23%), Positives = 223/567 (39%), Gaps = 97/567 (17%)
Query: 13 LRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETF-QVQVIDNGFGMGSDDVEKVGN 71
L S I+S+ V+EL NS+DA A V V++ F +++V DNG G+ + D +
Sbjct: 12 LSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAM 71
Query: 72 RYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALK 131
+Y+TSK +S +DLEN YGFRGEAL +I +A + + T L SG L
Sbjct: 72 KYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHIL- 130
Query: 132 ACEADVTRASAGTTVTVYNLFYQLPVR-------RKCMDPRLEFEKVRQRIEALSLMHPS 184
+ GTTVT LF LPVR +KC D E +K++ + + ++ P
Sbjct: 131 --SQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKD---EIKKIQDLLMSFGILKPD 185
Query: 185 ISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFE--LSGYI--- 239
+ + + +++ Q + D + G + + +E + LSG++
Sbjct: 186 LRIVFVH--NKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKC 243
Query: 240 ----SSEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLR 295
S + F+F+N R V + + KLI N
Sbjct: 244 DADHSFTSLSTPERSFIFINSRPVHQKDILKLI------------------RHHYNLKCL 285
Query: 296 HRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFV 355
ST LY ++ + + + DV + P K+ + QN +++L + E L
Sbjct: 286 KEST-RLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVLIAL----------ENLMT 334
Query: 356 ELSGEDIKEFSEDNG---FSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVK 412
G S +N S D L K +D +FN + K
Sbjct: 335 TCYGPLPSTNSYENNKTDVSAADIVLSKTAETD----------------VLFNKVESSGK 378
Query: 413 RKTTAEN--VNTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKM 470
+ + + Q+ ++ + KNT+D + G G+ + + N D + +
Sbjct: 379 NYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSS-EISNIDKNTKNAFQ 437
Query: 471 LEQETIVASEAGENEKHKKSFL---EHSSLENPCGTSLEMFLSPFQTPCHFEESGQD--- 524
+ V+ E + E K F+ +H+ EN H +ESG++
Sbjct: 438 DISMSNVSWENSQTEYSKTCFISSVKHTQSEN-------------GNKDHIDESGENEEE 484
Query: 525 --LEIWKESTTVNGMAANILKNNRIQN 549
LE E + NILKN+ +N
Sbjct: 485 AGLENSSEISADEWSRGNILKNSVGEN 511
>gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]
Length = 932
Score = 103 bits (256), Expect = 2e-21
Identities = 133/567 (23%), Positives = 223/567 (39%), Gaps = 97/567 (17%)
Query: 13 LRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETF-QVQVIDNGFGMGSDDVEKVGN 71
L S I+S+ V+EL NS+DA A V V++ F +++V DNG G+ + D +
Sbjct: 12 LSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAM 71
Query: 72 RYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALK 131
+Y+TSK +S +DLEN YGFRGEAL +I +A + + T L SG L
Sbjct: 72 KYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHIL- 130
Query: 132 ACEADVTRASAGTTVTVYNLFYQLPVR-------RKCMDPRLEFEKVRQRIEALSLMHPS 184
+ GTTVT LF LPVR +KC D E +K++ + + ++ P
Sbjct: 131 --SQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKD---EIKKIQDLLMSFGILKPD 185
Query: 185 ISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFE--LSGYI--- 239
+ + + +++ Q + D + G + + +E + LSG++
Sbjct: 186 LRIVFVH--NKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKC 243
Query: 240 ----SSEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLR 295
S + F+F+N R V + + KLI N
Sbjct: 244 DADHSFTSLSTPERSFIFINSRPVHQKDILKLI------------------RHHYNLKCL 285
Query: 296 HRSTPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFV 355
ST LY ++ + + + DV + P K+ + QN +++L + E L
Sbjct: 286 KEST-RLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVLIAL----------ENLMT 334
Query: 356 ELSGEDIKEFSEDNG---FSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVK 412
G S +N S D L K +D +FN + K
Sbjct: 335 TCYGPLPSTNSYENNKTDVSAADIVLSKTAETD----------------VLFNKVESSGK 378
Query: 413 RKTTAEN--VNTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKM 470
+ + + Q+ ++ + KNT+D + G G+ + + N D + +
Sbjct: 379 NYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSS-EISNIDKNTKNAFQ 437
Query: 471 LEQETIVASEAGENEKHKKSFL---EHSSLENPCGTSLEMFLSPFQTPCHFEESGQD--- 524
+ V+ E + E K F+ +H+ EN H +ESG++
Sbjct: 438 DISMSNVSWENSQTEYSKTCFISSVKHTQSEN-------------GNKDHIDESGENEEE 484
Query: 525 --LEIWKESTTVNGMAANILKNNRIQN 549
LE E + NILKN+ +N
Sbjct: 485 AGLENSSEISADEWSRGNILKNSVGEN 511
>gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]
Length = 893
Score = 92.8 bits (229), Expect = 2e-18
Identities = 131/565 (23%), Positives = 212/565 (37%), Gaps = 132/565 (23%)
Query: 13 LRSGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETF-QVQVIDNGFGMGSDDVEKVGN 71
L S I+S+ V+EL NS+DA A V V++ F +++V DNG G+ + D +
Sbjct: 12 LSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAM 71
Query: 72 RYFTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALK 131
+Y+TSK +S +DLEN YGFRGEAL +I +A + + T L SG L
Sbjct: 72 KYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHIL- 130
Query: 132 ACEADVTRASAGTTVTVYNLFYQLPVR-------RKCMDPRLEFEKVRQRIEALSLMHPS 184
+ GTTVT LF LPVR +KC D E +K++ + + ++ P
Sbjct: 131 --SQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKD---EIKKIQDLLMSFGILKPD 185
Query: 185 ISFSLRNDVSGSMVLQLPKTKDVCSRFCQIYGLGKSQKLREISFKYKEFELSGYI----- 239
+ I F + + LSG++
Sbjct: 186 L---------------------------------------RIVFVHNKIYLSGFLPKCDA 206
Query: 240 --SSEAHYNKNMQFLFVNKRLVLRTKLHKLIDFLLRKESIICKPKNGPTSRQMNSSLRHR 297
S + F+F+N R V + + KLI N
Sbjct: 207 DHSFTSLSTPERSFIFINSRPVHQKDILKLI------------------RHHYNLKCLKE 248
Query: 298 STPELYGIYVINVQCQFCEYDVCMEPAKTLIEFQNWDTLLFCIQEGVKMFLKQEKLFVEL 357
ST LY ++ + + + DV + P K+ + QN +++L + E L
Sbjct: 249 ST-RLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVLIAL----------ENLMTTC 297
Query: 358 SGEDIKEFSEDNG---FSLFDATLQKRVTSDERSNFQEACNNILDSYEMFNLQSKAVKRK 414
G S +N S D L K +D +FN + K
Sbjct: 298 YGPLPSTNSYENNKTDVSAADIVLSKTAETD----------------VLFNKVESSGKNY 341
Query: 415 TTAEN--VNTQSSRDSEATRKNTNDAFLYIYESGGPGHSKMTEPSLQNKDSSCSESKMLE 472
+ + + Q+ ++ + KNT+D + G G+ + + N D + +
Sbjct: 342 SNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSS-EISNIDKNTKNAFQDI 400
Query: 473 QETIVASEAGENEKHKKSFL---EHSSLENPCGTSLEMFLSPFQTPCHFEESGQD----- 524
+ V+ E + E K F+ +H+ EN H +ESG++
Sbjct: 401 SMSNVSWENSQTEYSKTCFISSVKHTQSEN-------------GNKDHIDESGENEEEAG 447
Query: 525 LEIWKESTTVNGMAANILKNNRIQN 549
LE E + NILKN+ +N
Sbjct: 448 LENSSEISADEWSRGNILKNSVGEN 472
>gi|4505913 PMS2 postmeiotic segregation increased 2 isoform a [Homo
sapiens]
Length = 862
Score = 83.2 bits (204), Expect = 2e-15
Identities = 78/293 (26%), Positives = 129/293 (44%), Gaps = 51/293 (17%)
Query: 15 SGLAISSLGQCVEELALNSIDAEAKCVAVRV-NMETFQVQVIDNGFGMGSDDVEKVGNRY 73
SG + SL V+EL NS+DA A + +++ + ++V DNG G+ ++ E + ++
Sbjct: 28 SGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEVSDNGCGVEEENFEGLTLKH 87
Query: 74 FTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALKAC 133
TSK DL +GFRGEAL+++ ++ + + + T + +GK ++
Sbjct: 88 HTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHASAKVGTRLMFDHNGKIIQKT 147
Query: 134 EADVTRASAGTTVTVYNLFYQLPVRRKCMDPRL--EFEKVRQRIEALSLMHPSISFSLRN 191
R GTTV+V LF LPVR K + E+ K+ Q + A ++ I S N
Sbjct: 148 PYPRPR---GTTVSVQQLFSTLPVRHKEFQRNIKKEYAKMVQVLHAYCIISAGIRVSCTN 204
Query: 192 DVS--------------------GSM-----------VLQLPKTKDVCSRFCQIYGLGKS 220
+ GS+ +QLP + VC YGL S
Sbjct: 205 QLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQSLIPFVQLPPSDSVCEE----YGLSCS 260
Query: 221 QKLREISFKYKEFELSGYISSEAH----YNKNMQFLFVNKRLVLRTKLHKLID 269
L + F +SG+IS H + + QF F+N+R K+ +L++
Sbjct: 261 DALHNL------FYISGFISQCTHGVGRSSTDRQFFFINRRPCDPAKVCRLVN 307
Score = 43.1 bits (100), Expect = 0.002
Identities = 22/80 (27%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 1308 IREQLELLQTTGGIQGTLPLTVQKVLASQACHGAIKFNDGLSLQESCRLIEALSSCQLPF 1367
+ E + +L + G+ P V+++ AS+AC ++ L+ E +LI + P+
Sbjct: 783 VDELIFMLSDSPGVM-CRPSRVKQMFASRACRKSVMIGTALNTSEMKKLITHMGEMDHPW 841
Query: 1368 QCAHGRPSMLPLADIDHLEQ 1387
C HGRP+M +A++ + Q
Sbjct: 842 NCPHGRPTMRHIANLGVISQ 861
>gi|239743246 PREDICTED: hypothetical protein XP_002342778 [Homo
sapiens]
Length = 255
Score = 58.2 bits (139), Expect = 6e-08
Identities = 41/147 (27%), Positives = 73/147 (49%), Gaps = 4/147 (2%)
Query: 15 SGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQ-VQVIDNGFGMGSDDVEKVGNRY 73
SG + SL V+++ NS+DA A + +++ ++V NG G+ ++ E + ++
Sbjct: 43 SGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKH 102
Query: 74 FTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALKAC 133
TSK DL +GF+G+AL+++ ++ + + + T + GK ++
Sbjct: 103 HTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIQKT 162
Query: 134 EADVTRASAGTTVTVYNLFYQLPVRRK 160
R GTTV+V LF LPVR K
Sbjct: 163 PYPHPR---GTTVSVKQLFSTLPVRHK 186
>gi|169170512 PREDICTED: similar to Postmeiotic segregation
increased 4-like protein [Homo sapiens]
Length = 255
Score = 58.2 bits (139), Expect = 6e-08
Identities = 41/147 (27%), Positives = 73/147 (49%), Gaps = 4/147 (2%)
Query: 15 SGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQ-VQVIDNGFGMGSDDVEKVGNRY 73
SG + SL V+++ NS+DA A + +++ ++V NG G+ ++ E + ++
Sbjct: 43 SGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKH 102
Query: 74 FTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALKAC 133
TSK DL +GF+G+AL+++ ++ + + + T + GK ++
Sbjct: 103 HTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIQKT 162
Query: 134 EADVTRASAGTTVTVYNLFYQLPVRRK 160
R GTTV+V LF LPVR K
Sbjct: 163 PYPHPR---GTTVSVKQLFSTLPVRHK 186
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 46.6 bits (109), Expect = 2e-04
Identities = 62/256 (24%), Positives = 112/256 (43%), Gaps = 18/256 (7%)
Query: 659 ASTLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFP 718
A SKESG+ + N + + L P+ S E +S+ D ++T
Sbjct: 235 AGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDD--NNTMEEVK 292
Query: 719 WYRHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGK-VENPLDTEVEESNG 777
+++SR T G S+P R+ SQ S E ++ + V+ P +E+N
Sbjct: 293 SDSTENSNSRDT----GLSQP--RRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANL 346
Query: 778 VTTNLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDED 837
+ S + + +++ ++R +N D + DSDSS + +SH L+ K S++E
Sbjct: 347 SSQENSSESQEEVV--SESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSE-SREEQ 403
Query: 838 CLEQQMPSL---RESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMS 894
+ SL ESP + ++ + +++ L SS S+ S + + ++Q S
Sbjct: 404 ADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQD---SS 460
Query: 895 RFNELPNSDSSRKDSK 910
R E NS S+ S+
Sbjct: 461 RSKEDSNSTESKSSSE 476
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 46.6 bits (109), Expect = 2e-04
Identities = 62/256 (24%), Positives = 112/256 (43%), Gaps = 18/256 (7%)
Query: 659 ASTLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFP 718
A SKESG+ + N + + L P+ S E +S+ D ++T
Sbjct: 219 AGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDD--NNTMEEVK 276
Query: 719 WYRHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGK-VENPLDTEVEESNG 777
+++SR T G S+P R+ SQ S E ++ + V+ P +E+N
Sbjct: 277 SDSTENSNSRDT----GLSQP--RRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANL 330
Query: 778 VTTNLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDED 837
+ S + + +++ ++R +N D + DSDSS + +SH L+ K S++E
Sbjct: 331 SSQENSSESQEEVV--SESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSE-SREEQ 387
Query: 838 CLEQQMPSL---RESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMS 894
+ SL ESP + ++ + +++ L SS S+ S + + ++Q S
Sbjct: 388 ADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQD---SS 444
Query: 895 RFNELPNSDSSRKDSK 910
R E NS S+ S+
Sbjct: 445 RSKEDSNSTESKSSSE 460
>gi|113722133 senataxin [Homo sapiens]
Length = 2677
Score = 40.4 bits (93), Expect = 0.012
Identities = 71/307 (23%), Positives = 133/307 (43%), Gaps = 62/307 (20%)
Query: 769 DTEVEESNGVTTNLSLQVEPDILLKDKN---RLENSDVCKITTMEHSD------SDSSCQ 819
DT V++ +G NLSL +P +L DKN + +N+ + K +++ + +++C+
Sbjct: 828 DTGVQKGDGFIHNLSL--DPSGVLDDKNGEQKSQNNVLPKEKQLKNEELVIFSFHENNCK 885
Query: 820 PAS-HILNSEKFPFSKDEDCLEQQ---------MPSLRESPMTLKELSLFNRKPLDLEKS 869
H+ E PF++ + E++ +P R+ M+ +++ +
Sbjct: 886 IQEFHVDGKELIPFTEMTNASEKKSSPFKDLMTVPESRDEEMSNSTSVIYSNLT---REQ 942
Query: 870 SESLASKLSRLKGSE--RETQTMGMMSRFNELP-NSDSSRKDSKLCSVLTQD---FCMLF 923
+ ++ K L S+ R+ + ++++ + + SDS + S+L + +D F
Sbjct: 943 APDISPKSDTLTDSQIDRDLHKLSLLAQASVITFPSDSPQNSSQLQRKVKEDKRCFTANQ 1002
Query: 924 NNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTENCVISETPLVLPYNNSKVTGKD 983
NN + + VI SDS D+ E L L K+T +D
Sbjct: 1003 NNVGDTSRGQVIIISDSDDDDD---------------------ERILSL----EKLTKQD 1037
Query: 984 SDVLIRAS-EQQIGSLDSPSGMLMNPVEDATGDQNGICFQSEESKARACSETEESNTCCS 1042
L R EQ + +++S NPV++ ++ FQ EES ++ C E E S+ S
Sbjct: 1038 KICLEREHPEQHVSTVNSKEEK--NPVKE---EKTETLFQFEESDSQ-CFEFESSSEVFS 1091
Query: 1043 DWQRHFD 1049
WQ H D
Sbjct: 1092 VWQDHPD 1098
>gi|157388975 coiled-coil domain containing 99 [Homo sapiens]
Length = 605
Score = 40.0 bits (92), Expect = 0.016
Identities = 50/216 (23%), Positives = 94/216 (43%), Gaps = 26/216 (12%)
Query: 745 LSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVC 804
L+L +L +E K + N L E+ + TNL QV D L ++K E V
Sbjct: 164 LALQIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQV--DRLKEEKEEREKEAVS 221
Query: 805 KITTMEHS---------DSDSSCQPASHILNSEKFPFSKDED---CLEQQMPSLRESPMT 852
+E + D + Q A + F++ ED +E+Q+ S++ +
Sbjct: 222 YYNALEKARVANQDLQVQLDQALQQALDPNSKGNSLFAEVEDRRAAMERQLISMKVKYQS 281
Query: 853 LKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELPNSDSSRKDSKLC 912
LK+ ++FNR+ + K + L ++KGS+ E + + E N + ++
Sbjct: 282 LKKQNVFNREQMQRMKLQ---IATLLQMKGSQTEFEQQERLLAMLEQKNGEIKHLLGEIR 338
Query: 913 SVLTQDFCMLFNNKHEKTENGVIPTSDSAT-QDNSF 947
++ + F L+++ K P+ DS T +DN++
Sbjct: 339 NL--EKFKNLYDSMESK------PSVDSGTLEDNTY 366
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 37.4 bits (85), Expect = 0.10
Identities = 49/222 (22%), Positives = 86/222 (38%), Gaps = 22/222 (9%)
Query: 743 KKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVT-------TNLSLQVEPDILLKDK 795
+KL L SQ+ L+ +Q K + L+ E ++ + N S EPD+ ++D
Sbjct: 1007 RKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDL 1066
Query: 796 NRLENSDVCKITTMEHSDSDS-------SCQPASHILNSEKFPFSKDEDCLEQQMPSLRE 848
+ ++ K + S S S H+L++E ++ L QQ S+R
Sbjct: 1067 RKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRR 1126
Query: 849 SPMTLKELSLFNRKPL----DLEKSSESLASKLSRLKGSERETQTMGMMSRFNELPNSDS 904
LK R L ++ K + + K E+ET+ + M ++
Sbjct: 1127 RQTALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLL 1186
Query: 905 SRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNS 946
+K+ K L Q L+ ++ G PT + T D S
Sbjct: 1187 KKKEEK----LNQLESSLWEEASDEGTLGGSPTKKAVTFDLS 1224
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 37.4 bits (85), Expect = 0.10
Identities = 59/291 (20%), Positives = 109/291 (37%), Gaps = 30/291 (10%)
Query: 613 VQNEKTKSTETEHSFKNYVRPGPTRAQETFGNRTRHSVETPDIKDLASTLSKESGQLPNK 672
++NEK K+TE QET + DI + + Q+ N
Sbjct: 506 LENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENL 565
Query: 673 KNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCILSDTSPSFPWYR-HVSNDSRKTD 731
+ T + LE + + K+ + C L + + R V N ++ +
Sbjct: 566 QETETQLRNELE---------YVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIE 616
Query: 732 KLIGFSKPIVRKKLSLSSQLG-----------SLEKFKRQYGKVENPLDTEVEESNGVTT 780
+L +K + +K + S QL LE K+++G++ + E+E+
Sbjct: 617 ELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEE 676
Query: 781 NLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDED--- 837
NL +VE ++ D+ ++ K +H ++ H +K +D +
Sbjct: 677 NLLEEVEKAKVIADEAVKLQKEIDK--RCQHKIAEMVALMEKHKHQYDKIIEERDSELGL 734
Query: 838 --CLEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERE 886
EQ+ SLR S ELS + L ++K E + +LK +E
Sbjct: 735 YKSKEQEQSSLRASLEI--ELSNLKAELLSVKKQLEIEREEKEKLKREAKE 783
Score = 31.6 bits (70), Expect = 5.7
Identities = 35/161 (21%), Positives = 73/161 (45%), Gaps = 18/161 (11%)
Query: 720 YRHVSNDSRKTDK-LIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGV 778
+ ++ + + T++ LIG + ++ L QL ++ ++ Y K L TE+E
Sbjct: 453 FEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLK 512
Query: 779 TTNLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDC 838
T L+ +K LEN ++ T E SD + +N+ K K E+
Sbjct: 513 NTELTSHC-------NKLSLENKEL----TQETSDMTLELKNQQEDINNNK----KQEER 557
Query: 839 LEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSR 879
+ +Q+ +L+E+ L+ + R+ +L++ + + KL +
Sbjct: 558 MLKQIENLQETETQLRNELEYVRE--ELKQKRDEVKCKLDK 596
Score = 31.2 bits (69), Expect = 7.5
Identities = 57/253 (22%), Positives = 96/253 (37%), Gaps = 41/253 (16%)
Query: 769 DTEVEESNGV------------TTNLSLQVEPDILLKDKNRLE-NSDVCKITTMEHSDSD 815
+T++EESN TT SL+ ++L ++ RLE N D KI TME
Sbjct: 360 ETQMEESNKARAAHSFVVTEFETTVCSLE---ELLRTEQQRLEKNEDQLKILTMELQKKS 416
Query: 816 SSCQPASHILNSEKFPFSKDEDCLEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLAS 875
S + + + N+++ LE+ L E L E F + +L+ + + L
Sbjct: 417 SELEEMTKLTNNKEVE-------LEELKKVLGEKETLLYENKQFEKIAEELKGTEQEL-- 467
Query: 876 KLSRLKGSERETQ---------TMGMMSRFNELPNSDSSRKDSKLCSVLTQDFC--MLFN 924
+ L+ E+E T E+ + + ++ KL + C +
Sbjct: 468 -IGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLE 526
Query: 925 NKHEKTENGVIPTSDSATQDNSFNKNSKTHSNS-NTTENCVISETPL--VLPYNNSKVTG 981
NK E T+ T + Q N N K EN +ET L L Y ++
Sbjct: 527 NK-ELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQ 585
Query: 982 KDSDVLIRASEQQ 994
K +V + + +
Sbjct: 586 KRDEVKCKLDKSE 598
>gi|158534059 formin binding protein 4 [Homo sapiens]
Length = 1017
Score = 37.4 bits (85), Expect = 0.10
Identities = 79/382 (20%), Positives = 140/382 (36%), Gaps = 59/382 (15%)
Query: 743 KKLSLSSQLGSLEKFKRQYGKVENP----LDTEVEESNGVTTNLSLQVEPDILLKDKNRL 798
K +S+SS KR+ K N L EE GV +L + P+ + +++ R
Sbjct: 282 KTISVSSSKSGPVIAKREVKKEVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEEERW 341
Query: 799 ENSDVCKITTM-EHSDSDSSCQPASHILNSEKFPFSKDEDCLEQQMPSLRESPMTLKELS 857
+CK + E ++ ++ + A+ I+ ++ ED ++ + S+ +S + +E
Sbjct: 342 RRKVICKEEPVSEVKETSTTVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEE 401
Query: 858 LFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELPNSDSSRKDSKLCSVLTQ 917
+ L+LE E ++L L+ + G +S P SD S+ S Q
Sbjct: 402 ---QDTLELELVLERKKAELRALEEGD------GSVS--GSSPRSDISQPAS-------Q 443
Query: 918 DFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNS--------------NTTENC 963
D +K K + V TS +T +S T N N+ +
Sbjct: 444 DGMRRLMSKRGKWKMFVRATSPESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKEM 503
Query: 964 VISETPLVLPYNNSKVTGKDSDVLIRASE----------------QQIGSLDSPSGMLMN 1007
+ E+P + + ++ D+ + E Q I +
Sbjct: 504 EVEESPEKIKVQTTPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTET 563
Query: 1008 PVED-ATGDQNGICFQSEESKARACSETEESNTCCSDWQRHFDVALGRMVYVNKMTGLST 1066
+ D G NG + + A + E N W H+D R YVN+ +G S
Sbjct: 564 RIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQ 623
Query: 1067 FIAP-----TEDIQAACTKDLT 1083
+ P E+ QA +D T
Sbjct: 624 WEFPDGEEEEEESQAQENRDET 645
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 36.2 bits (82), Expect = 0.23
Identities = 55/271 (20%), Positives = 104/271 (38%), Gaps = 8/271 (2%)
Query: 769 DTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSE 828
DT +SNG N + + D K + ++SD + SDS S S NS
Sbjct: 520 DTNNSDSNGNGNNGN--DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS- 576
Query: 829 KFPFSKDEDCLEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQ 888
S D D + +S + S + D SS+S S S+ S+ E+
Sbjct: 577 ----SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
Query: 889 TMGMMSRFNELPNSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFN 948
+ S+ + ++ S D+ S + ++ + + + S + D+S +
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692
Query: 949 KNSKTHSNSNTTENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNP 1008
+S S S+ + + S++ +NS + DS +S+ S S S N
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752
Query: 1009 VEDA-TGDQNGICFQSEESKARACSETEESN 1038
+ + + D + S+ S + S++ S+
Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783
Score = 35.0 bits (79), Expect = 0.52
Identities = 77/404 (19%), Positives = 139/404 (34%), Gaps = 24/404 (5%)
Query: 651 ETPDIKDLASTLSKESGQLPNKKNCRTNISYGLENEPTATYTMFSAFQEGSKKSQTDCIL 710
++ D ++ S +G N N +++ G + + + S + S S +D
Sbjct: 514 DSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSD 573
Query: 711 SDTSPSFPWYRHVSNDSRKTDKL--IGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPL 768
S++S S+DS +D S S SS K K E+
Sbjct: 574 SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633
Query: 769 DTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSE 828
+S+ +N S + N +SD + + SDS SS ++ +S+
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSD--SSDSSDSSDSSSSSDSSNSSDSSD 691
Query: 829 KFPFSKDEDCLEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQ 888
S + + S +S + + S N D SS+S S S ++
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDS-SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSS 750
Query: 889 TMGMMSRFNELPNS-------------DSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVI 935
S ++ NS DSS S + D N+ +
Sbjct: 751 NSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS 810
Query: 936 PTSDSATQDNSFNKNSKTHSNSNTTENCVISETPLVLPYNNSKVTGKDSDVLIRASEQQI 995
+SDS+ D+S + +S S+S+ + N S ++ G DSD R+
Sbjct: 811 DSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD------SSDSSDGSDSDSSNRSDSSNS 864
Query: 996 GSLDSPSGMLMNPVEDATGDQNGICFQSEESKARACSETEESNT 1039
S + + D N S+ S + S+++ S++
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS 908
Score = 34.7 bits (78), Expect = 0.68
Identities = 37/174 (21%), Positives = 68/174 (39%), Gaps = 3/174 (1%)
Query: 865 DLEKSSESLASKLSRLKGSERETQTMGMMSRFNELPNSDSSRKDSKLCSVLTQDFCMLFN 924
D SS+ S S S + + N +SDSS + S + D +
Sbjct: 843 DSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSD 902
Query: 925 NKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTENCVISETPLVLPYNNSKVTGKDS 984
+ + N + S + D+S + NS +SNS+ + N S++ +NS + S
Sbjct: 903 SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS--SDSSDSSDSSNSSDSSNSS 960
Query: 985 DVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGICFQSEESKARACSETEESN 1038
D + S DS + D++ D + S+ S + S++ +S+
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSS-DSSDSSDSSDSSNSSDSSDSSDSS 1013
Score = 33.1 bits (74), Expect = 2.0
Identities = 45/248 (18%), Positives = 83/248 (33%)
Query: 796 NRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLEQQMPSLRESPMTLKE 855
N ++SD + S S +S+ +S S D D + S +
Sbjct: 863 NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD 922
Query: 856 LSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNELPNSDSSRKDSKLCSVL 915
S + + S S +S S S + + N +SDS+ DS S
Sbjct: 923 SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982
Query: 916 TQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTENCVISETPLVLPYN 975
+ ++ + + + S + D+S + NS SNS+ + N S +
Sbjct: 983 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Query: 976 NSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGDQNGICFQSEESKARACSETE 1035
+ DS +S+ S S S + + + ++ S S + S
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102
Query: 1036 ESNTCCSD 1043
++ SD
Sbjct: 1103 SDSSDSSD 1110
>gi|216548091 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 36.2 bits (82), Expect = 0.23
Identities = 45/199 (22%), Positives = 94/199 (47%), Gaps = 24/199 (12%)
Query: 725 NDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLS- 783
N + D+L+ +++ + S SS L +E +++ ++E D E++ + + +
Sbjct: 36 NLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGK-DEEIKRAEDLCRLMKE 94
Query: 784 -LQVEPDILLKDKNRLENSD--VCKITTMEH--SDSDSSCQPASHILNSEKFPFSKDEDC 838
L+ E ++ + K+ +E + ++ +E S S + C LN E+ K
Sbjct: 95 KLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKK---- 150
Query: 839 LEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNE 898
+ ++ LR + +KEL + L+K+ +SLAS+L +LK + T+ +S
Sbjct: 151 ISSELEMLR---VKVKELESSEDR---LDKTEQSLASELEKLK-----SLTLSFVSERKY 199
Query: 899 LPNSDSSRKDSKLCSVLTQ 917
L ++ +++ KL LTQ
Sbjct: 200 L--NEKEKENEKLIKELTQ 216
>gi|216548085 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 36.2 bits (82), Expect = 0.23
Identities = 45/199 (22%), Positives = 94/199 (47%), Gaps = 24/199 (12%)
Query: 725 NDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLS- 783
N + D+L+ +++ + S SS L +E +++ ++E D E++ + + +
Sbjct: 36 NLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGK-DEEIKRAEDLCRLMKE 94
Query: 784 -LQVEPDILLKDKNRLENSD--VCKITTMEH--SDSDSSCQPASHILNSEKFPFSKDEDC 838
L+ E ++ + K+ +E + ++ +E S S + C LN E+ K
Sbjct: 95 KLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKK---- 150
Query: 839 LEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSRFNE 898
+ ++ LR + +KEL + L+K+ +SLAS+L +LK + T+ +S
Sbjct: 151 ISSELEMLR---VKVKELESSEDR---LDKTEQSLASELEKLK-----SLTLSFVSERKY 199
Query: 899 LPNSDSSRKDSKLCSVLTQ 917
L ++ +++ KL LTQ
Sbjct: 200 L--NEKEKENEKLIKELTQ 216
>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 34.7 bits (78), Expect = 0.68
Identities = 52/239 (21%), Positives = 89/239 (37%), Gaps = 31/239 (12%)
Query: 765 ENPLDTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVCKITTM------EHSDSDSSC 818
E+ +D E G + S+ ++ + KD N E D T HS D +C
Sbjct: 302 EDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKTC 361
Query: 819 QPASHILNSEKFPFS-KDEDCLEQQMPSLRESPMT-------------LKELSLFNRKPL 864
Q ++++ + +S + E P L+E+P T L S ++P
Sbjct: 362 QKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPR 421
Query: 865 DLEKSSESLASK--LSRLKGSERETQTMGMMSRFNE-----LPNSDSSRKDSKLCSVLTQ 917
E S + L S+ LS K +++ + F+E L N +++K
Sbjct: 422 SAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRN 481
Query: 918 DFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTENCVISETPLVLPYNN 976
F K+E++ V+P T+ F + T SN + ET + NN
Sbjct: 482 KFATFLQRKNEESGAVVVP----GTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENN 536
>gi|39995069 exonuclease 1 isoform a [Homo sapiens]
Length = 803
Score = 34.7 bits (78), Expect = 0.68
Identities = 52/239 (21%), Positives = 89/239 (37%), Gaps = 31/239 (12%)
Query: 765 ENPLDTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVCKITTM------EHSDSDSSC 818
E+ +D E G + S+ ++ + KD N E D T HS D +C
Sbjct: 302 EDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKTC 361
Query: 819 QPASHILNSEKFPFS-KDEDCLEQQMPSLRESPMT-------------LKELSLFNRKPL 864
Q ++++ + +S + E P L+E+P T L S ++P
Sbjct: 362 QKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPR 421
Query: 865 DLEKSSESLASK--LSRLKGSERETQTMGMMSRFNE-----LPNSDSSRKDSKLCSVLTQ 917
E S + L S+ LS K +++ + F+E L N +++K
Sbjct: 422 SAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRN 481
Query: 918 DFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTENCVISETPLVLPYNN 976
F K+E++ V+P T+ F + T SN + ET + NN
Sbjct: 482 KFATFLQRKNEESGAVVVP----GTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENN 536
>gi|18491016 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 34.7 bits (78), Expect = 0.68
Identities = 52/239 (21%), Positives = 89/239 (37%), Gaps = 31/239 (12%)
Query: 765 ENPLDTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVCKITTM------EHSDSDSSC 818
E+ +D E G + S+ ++ + KD N E D T HS D +C
Sbjct: 302 EDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKTC 361
Query: 819 QPASHILNSEKFPFS-KDEDCLEQQMPSLRESPMT-------------LKELSLFNRKPL 864
Q ++++ + +S + E P L+E+P T L S ++P
Sbjct: 362 QKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPR 421
Query: 865 DLEKSSESLASK--LSRLKGSERETQTMGMMSRFNE-----LPNSDSSRKDSKLCSVLTQ 917
E S + L S+ LS K +++ + F+E L N +++K
Sbjct: 422 SAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRN 481
Query: 918 DFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTENCVISETPLVLPYNN 976
F K+E++ V+P T+ F + T SN + ET + NN
Sbjct: 482 KFATFLQRKNEESGAVVVP----GTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENN 536
>gi|14249456 zinc finger protein 514 [Homo sapiens]
Length = 400
Score = 34.3 bits (77), Expect = 0.88
Identities = 34/132 (25%), Positives = 55/132 (41%), Gaps = 13/132 (9%)
Query: 485 EKHKKSFLEHSSLENPCGTSLEMFLSPFQTPCHFEESGQDLEIWKESTTV------NGMA 538
EKH + L+ S L+ CG ++ + + H ++ I K +TT+ NG
Sbjct: 101 EKHIQDVLQFSKLKAACGCDGQLEMQQIKQERHLKQMS---TIHKSATTLSRDYKWNGFG 157
Query: 539 ANILKNNRIQNQPKRFKDATEVGCQPLPFATTLWGVHSAQTEKEKKK-ESSNCGRRNVF- 596
++ + + NQ C F TL G +S +T EKK + + CG+ F
Sbjct: 158 RSLGLRSVLVNQHSILMGEGSYKCD-TEFRQTLGGNNSQRTHPEKKSCKCNECGKSFHFQ 216
Query: 597 -SYGRVKLCSTG 607
R + C TG
Sbjct: 217 SELRRHQRCHTG 228
>gi|50083293 coiled-coil domain containing 123 [Homo sapiens]
Length = 783
Score = 34.3 bits (77), Expect = 0.88
Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 16/156 (10%)
Query: 744 KLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLSLQVEPDILLKDKNRLENSDV 803
KL L LE+ + Q K ++ ++E + +T L L +E ++K EN +
Sbjct: 431 KLVLEENKLLLEQLEIQQRKAKDSHQERLQEVSKLTKQLML-LEAKTHGQEKELAENREQ 489
Query: 804 CKITTME------HSDSDSSCQPASHILNSEKFPFSKDEDCLEQQMPSLRESPMTLKELS 857
+I + HSD + + I+N K K+E+ +M L E L+
Sbjct: 490 LEILRAKCQELKTHSDGKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQA-- 547
Query: 858 LFNRKPLDLEKSS-----ESLASKLSRLKGSERETQ 888
+K L LEK+S ++L ++L R + R++Q
Sbjct: 548 --QKKSLLLEKNSLTEQNKALEAELERAQKINRKSQ 581
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 33.9 bits (76), Expect = 1.2
Identities = 57/296 (19%), Positives = 116/296 (39%), Gaps = 40/296 (13%)
Query: 737 SKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLSLQV----EPDILL 792
S+ R+ L + +L +E+ + L T++++ NL Q+ + L
Sbjct: 1034 SQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL 1093
Query: 793 KDKN---RLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLEQQMPSLRES 849
+++N + +N+ + + +S S S + +L + +++E +++ RE
Sbjct: 1094 QEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE-----RED 1148
Query: 850 PMTLKELSLFNRKPLDL-----EKSSESLASKLSRLKGSER--ETQTMGMMSRFNELPNS 902
+L + + + + L+L ESL SK LK + + E + + R+N+L
Sbjct: 1149 LKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQ 1208
Query: 903 DSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTEN 962
+D + + Q+ +L N HE T + K + N T +
Sbjct: 1209 KGQLEDLEKMLKVEQEKMLLENKNHE-------------TVAAEYKKLCGENDRLNHTYS 1255
Query: 963 CVISETPLVLP--------YNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVE 1010
++ ET ++ NNSK+ + ++Q LD S L N E
Sbjct: 1256 QLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCE 1311
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 33.9 bits (76), Expect = 1.2
Identities = 57/296 (19%), Positives = 116/296 (39%), Gaps = 40/296 (13%)
Query: 737 SKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLSLQV----EPDILL 792
S+ R+ L + +L +E+ + L T++++ NL Q+ + L
Sbjct: 1033 SQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL 1092
Query: 793 KDKN---RLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCLEQQMPSLRES 849
+++N + +N+ + + +S S S + +L + +++E +++ RE
Sbjct: 1093 QEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE-----RED 1147
Query: 850 PMTLKELSLFNRKPLDL-----EKSSESLASKLSRLKGSER--ETQTMGMMSRFNELPNS 902
+L + + + + L+L ESL SK LK + + E + + R+N+L
Sbjct: 1148 LKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQ 1207
Query: 903 DSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTEN 962
+D + + Q+ +L N HE T + K + N T +
Sbjct: 1208 KGQLEDLEKMLKVEQEKMLLENKNHE-------------TVAAEYKKLCGENDRLNHTYS 1254
Query: 963 CVISETPLVLP--------YNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVE 1010
++ ET ++ NNSK+ + ++Q LD S L N E
Sbjct: 1255 QLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCE 1310
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 33.9 bits (76), Expect = 1.2
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 16/124 (12%)
Query: 744 KLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLSLQV---------EPDILLKD 794
K LSSQ+ EK + + ++ L+ EVE+ + +T NL +Q+ E ++ L
Sbjct: 834 KQRLSSQI---EKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNT 890
Query: 795 KNRLENSDVCKITTMEHSDSDSSCQPASHI--LNSEKFPFSK-DEDCLEQQMPSLRESPM 851
K L+N+ +I T++ S+ Q AS + P +K D D L Q+ E
Sbjct: 891 KELLKNAQK-EIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVN 949
Query: 852 TLKE 855
LKE
Sbjct: 950 DLKE 953
Score = 33.5 bits (75), Expect = 1.5
Identities = 44/225 (19%), Positives = 83/225 (36%), Gaps = 11/225 (4%)
Query: 722 HVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTN 781
H + T+++ I R SL++ ++ K KV +T ++ + +
Sbjct: 1364 HTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIID 1423
Query: 782 LSLQVEPDILLKD-----KNRLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDE 836
+ +V+ +K K + E + ME S S H+ E +
Sbjct: 1424 IQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETL 1483
Query: 837 DCLEQQMPSLRESPMTL-KELSLFNRKPLDLEKSSESLASKLSRLKGSERETQTMGMMSR 895
+ E + SL L K LS + +L++ + L S+LSRL+ ++ T R
Sbjct: 1484 NQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLR 1543
Query: 896 FNELPNSDSSRK-----DSKLCSVLTQDFCMLFNNKHEKTENGVI 935
+ +RK SK+ + + N+ K NG +
Sbjct: 1544 QQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGAL 1588
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 33.9 bits (76), Expect = 1.2
Identities = 46/211 (21%), Positives = 92/211 (43%), Gaps = 24/211 (11%)
Query: 710 LSDTSPSFPWYRHVSNDSRKTDKLIGFSKPIVRKKLSLSSQLGSLEK-FKRQYGKVENPL 768
+S+T+ S + +S + D+ I + ++ SL SQ+ +L+K + + + +
Sbjct: 268 VSETTTSRQNEKEISQKCQVLDEDIDAKQKEIQ---SLKSQISALQKGYSKVLCQTLSER 324
Query: 769 DTEV----------EESNGVTTNLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSC 818
++E+ + N +T+ + ++ DIL KD+ + + ++ D D
Sbjct: 325 NSEITSLKNEGENLKRDNAITSGMVSSLQKDILAKDEQVQQLKEEVSHLKSQNKDKDHQL 384
Query: 819 QPASHILNSEKFPFSKDEDCLEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLS 878
+ + K+E E LRE+ KEL L + D+EK + L ++L
Sbjct: 385 EAL-----GSRCSVLKEELKQEDAHRELREAQE--KELKLCKTQIQDMEKEMKKLRAEL- 436
Query: 879 RLKGSERE--TQTMGMMSRFNELPNSDSSRK 907
R +E+ ++T+ S+ E DS RK
Sbjct: 437 RKSCTEQSVISRTLREKSKVEEKLQEDSRRK 467
>gi|37595553 ring finger protein 111 [Homo sapiens]
Length = 986
Score = 33.9 bits (76), Expect = 1.2
Identities = 63/284 (22%), Positives = 117/284 (41%), Gaps = 34/284 (11%)
Query: 720 YRHVSNDSRKTDKLIGFS-----KPIVRKKLSLSSQLG-----SLEKFKRQYGKVENPLD 769
+ H+ +DS+K +K + + K +V +K S Q G + K + + L
Sbjct: 64 FSHLCDDSQKQEKEMNGNQQEQEKSLVVRKKRKSQQAGPSYVQNCVKENQGILGLRQHLG 123
Query: 770 TEVEESNGVTTNLSLQVEPDILLKDKNRLENSDVCKITTMEHSDSDSSCQPASHILNSEK 829
T +E N + + L L + SD K ++ HS + + + SH S K
Sbjct: 124 TPSDEDNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHK 183
Query: 830 FPFSKDEDC--LEQQMPSLRESPMTLKELSLFNRKPLDLEKSSESLASKLSRLKGSERET 887
+P ++ E L + P L S +L+ L RK SS+ + R+ ++
Sbjct: 184 WPRTETESVSGLLMKRPCLHGS--SLRRLPC--RKRFVKNNSSQRTQKQKERILMQRKKR 239
Query: 888 QTMGMMSRFNELPNSDSSRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSF 947
+ + ++ LP+S SS ++ L S + ++ E E+ + S++
Sbjct: 240 EVLA-RRKYALLPSSSSS-SENDLSSESSS------SSSTEGEEDLFVSASEN------- 284
Query: 948 NKNSKTHSNSNTTENCVI---SETPLVLPYNNSKVTGKDSDVLI 988
++N+ + + E+ V+ S TP V VT DS+V I
Sbjct: 285 HQNNPAVPSGSIDEDVVVIEASSTPQVTANEEINVTSTDSEVEI 328
>gi|229577185 epidermal growth factor receptor pathway substrate 15
isoform B [Homo sapiens]
Length = 582
Score = 33.1 bits (74), Expect = 2.0
Identities = 63/292 (21%), Positives = 111/292 (38%), Gaps = 38/292 (13%)
Query: 742 RKKLSLSSQLGSLEKFKRQYGKVENPLDTEVEESNGVTTNLSLQVEP-----DILLKDKN 796
R+K ++ L E +Q L EV+ N L Q + D L + K
Sbjct: 33 REKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKA 92
Query: 797 RLENSDVCKITTMEHSDSDSSCQPASHILNSEKFPFSKDEDCL---EQQMPSLRESPMTL 853
+LE + + C + +++S K + E + E+++ RE
Sbjct: 93 QLEE---------QLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKARE----- 138
Query: 854 KELSLFNRKPLDLEKSSESLASKL----SRLKGSERETQTMGM-MSRFNELPNSDS---- 904
ELS ++ +LE+S ES ++L L+ S++E +M M + +L N +S
Sbjct: 139 -ELSRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKDLENHNSQLNW 197
Query: 905 -SRKDSKLCSVLTQDFCMLFNNKHEKTENGVIPTSDSATQDNSFNKNSKTHSNSNTTENC 963
S S L + T D+C L + E S + ++ S S+ +
Sbjct: 198 CSSPHSILVNGAT-DYCSLSTSSSETANLNEHVEGQSNLESEPIHQESPARSSPELLPSG 256
Query: 964 VISETPLVLPYNNSKVTGKDSDVLIRASEQQIGSLDSPSGMLMNPVEDATGD 1015
V E + + D++ + E+ ++DS S L PV D D
Sbjct: 257 VTDENEVTTAVTEKVCSELDNN--RHSKEEDPFNVDSSS--LTGPVADTNLD 304
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,962,068
Number of Sequences: 37866
Number of extensions: 2295858
Number of successful extensions: 6766
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 6648
Number of HSP's gapped (non-prelim): 141
length of query: 1429
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1314
effective length of database: 13,892,928
effective search space: 18255307392
effective search space used: 18255307392
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.