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Search of human proteins with 91106928
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|91106928 beta chimerin isoform 1 [Homo sapiens]
(332 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 687 0.0
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 575 e-164
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 454 e-128
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 426 e-119
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 132 3e-31
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 132 6e-31
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 132 6e-31
gi|91208437 GEM interacting protein [Homo sapiens] 132 6e-31
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 130 1e-30
gi|188497642 ARHGAP15 [Homo sapiens] 130 1e-30
gi|23510413 sorting nexin 26 [Homo sapiens] 130 2e-30
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 130 2e-30
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 129 4e-30
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 129 4e-30
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 128 6e-30
gi|156119615 myosin IXA [Homo sapiens] 128 8e-30
gi|208022687 GTPase regulator associated with the focal adhesion... 128 8e-30
gi|7662208 GTPase regulator associated with the focal adhesion k... 128 8e-30
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] 127 1e-29
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 126 3e-29
gi|4505507 oligophrenin 1 [Homo sapiens] 123 3e-28
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi... 122 6e-28
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi... 122 6e-28
gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens] 120 2e-27
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 120 2e-27
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 120 2e-27
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 119 3e-27
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 119 3e-27
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 118 8e-27
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 117 1e-26
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 687 bits (1773), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MFSEELWLENEKKCAVVRKSKQGRKRQELLAVAFGVKVGVKGGFLWPPLKLFACSQISSL 60
MFSEELWLENEKKCAVVRKSKQGRKRQELLAVAFGVKVGVKGGFLWPPLKLFACSQISSL
Sbjct: 1 MFSEELWLENEKKCAVVRKSKQGRKRQELLAVAFGVKVGVKGGFLWPPLKLFACSQISSL 60
Query: 61 VRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQC 120
VRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQC
Sbjct: 61 VRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQC 120
Query: 121 SKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSG 180
SKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSG
Sbjct: 121 SKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSG 180
Query: 181 FTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAA 240
FTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAA
Sbjct: 181 FTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAA 240
Query: 241 KISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLM 300
KISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLM
Sbjct: 241 KISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLM 300
Query: 301 RPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332
RPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
Sbjct: 301 RPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 575 bits (1483), Expect = e-164
Identities = 277/280 (98%), Positives = 278/280 (99%)
Query: 53 ACSQISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDC 112
A +ISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDC
Sbjct: 189 AVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDC 248
Query: 113 GLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKS 172
GLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKS
Sbjct: 249 GLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKS 308
Query: 173 EGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDT 232
EGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDT
Sbjct: 309 EGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDT 368
Query: 233 YSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLG 292
YSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLG
Sbjct: 369 YSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLG 428
Query: 293 IVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332
IVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
Sbjct: 429 IVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 454 bits (1169), Expect = e-128
Identities = 212/277 (76%), Positives = 245/277 (88%)
Query: 56 QISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLN 115
+++SLVRRA L N+ YEK HNFKVHTFRGPHWCEYCANFMWGLIAQGV+C+DCGLN
Sbjct: 183 RLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLN 242
Query: 116 VHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGL 175
VHKQCSK VPNDC+PDLK +KKVY CDLTTLVKAH T+RPMVVD+CIREIE+RGL SEGL
Sbjct: 243 VHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGL 302
Query: 176 YRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSK 235
YRVSGF++ IEDVKMAFDRDGEKADIS N+Y DINIITGALKLYFRDLPIP+ITYD Y K
Sbjct: 303 YRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPK 362
Query: 236 FIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVF 295
FI++AKI + DE+LE +HE L LLPPAH ETLRYLM HLK+VT++EK+N MNAENLGIVF
Sbjct: 363 FIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVF 422
Query: 296 GPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332
GPTLMR PE + L+D+RYQ+L+V++LI+NED+LF
Sbjct: 423 GPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 426 bits (1096), Expect = e-119
Identities = 197/251 (78%), Positives = 227/251 (90%)
Query: 82 KVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCC 141
+VHTFRGPHWCEYCANFMWGLIAQGV+C+DCGLNVHKQCSK VPNDC+PDLK +KKVY C
Sbjct: 183 RVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSC 242
Query: 142 DLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADI 201
DLTTLVKAH T+RPMVVD+CIREIE+RGL SEGLYRVSGF++ IEDVKMAFDRDGEKADI
Sbjct: 243 DLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADI 302
Query: 202 SANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPP 261
S N+Y DINIITGALKLYFRDLPIP+ITYD Y KFI++AKI + DE+LE +HE L LLPP
Sbjct: 303 SVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPP 362
Query: 262 AHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIV 321
AH ETLRYLM HLK+VT++EK+N MNAENLGIVFGPTLMR PE + L+D+RYQ+L+V
Sbjct: 363 AHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVV 422
Query: 322 QILIENEDVLF 332
++LI+NED+LF
Sbjct: 423 ELLIKNEDILF 433
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 132 bits (333), Expect = 3e-31
Identities = 71/182 (39%), Positives = 106/182 (58%)
Query: 151 NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDIN 210
N P++VDIC + +E RGL+ G+YRV G I ++ ++ DI + + D+N
Sbjct: 1158 NRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDDKWRDLN 1217
Query: 211 IITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYL 270
+I+ LK +FR LP P+ T D Y+ FI+A + + +RL+ + ++ LP HYETL++L
Sbjct: 1218 VISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKFL 1277
Query: 271 MIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDV 330
HLK V N + N M NL IVFGPTL+R ED+ + M Q IV+ LI++ D
Sbjct: 1278 SAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDW 1337
Query: 331 LF 332
F
Sbjct: 1338 FF 1339
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 132 bits (331), Expect = 6e-31
Identities = 68/190 (35%), Positives = 116/190 (61%), Gaps = 2/190 (1%)
Query: 137 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 196
+V+ C L L + ++ P V CIR +EARGL +GLYR+SG I+ ++ D D
Sbjct: 325 QVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD- 383
Query: 197 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 256
E+ D+ + D+++ITGALKL+FR+LP P+ + + +FI A K+ + R V +++
Sbjct: 384 ERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLV 443
Query: 257 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRY 316
LP +++TLR L HL +V + + N M+ +++ IVFGPTL+RP + T + M +
Sbjct: 444 RSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPM-TMVF 502
Query: 317 QKLIVQILIE 326
Q +V+++++
Sbjct: 503 QNQVVELILQ 512
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 132 bits (331), Expect = 6e-31
Identities = 68/190 (35%), Positives = 116/190 (61%), Gaps = 2/190 (1%)
Query: 137 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 196
+V+ C L L + ++ P V CIR +EARGL +GLYR+SG I+ ++ D D
Sbjct: 352 QVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHD- 410
Query: 197 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 256
E+ D+ + D+++ITGALKL+FR+LP P+ + + +FI A K+ + R V +++
Sbjct: 411 ERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLV 470
Query: 257 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRY 316
LP +++TLR L HL +V + + N M+ +++ IVFGPTL+RP + T + M +
Sbjct: 471 RSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPM-TMVF 529
Query: 317 QKLIVQILIE 326
Q +V+++++
Sbjct: 530 QNQVVELILQ 539
>gi|91208437 GEM interacting protein [Homo sapiens]
Length = 970
Score = 132 bits (331), Expect = 6e-31
Identities = 90/275 (32%), Positives = 136/275 (49%), Gaps = 28/275 (10%)
Query: 77 KTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC-QPDLKRI 135
+TH + RGP C C FM G C +C L HK+C + + C L
Sbjct: 492 QTHQLR--RLRGPAKCRECEAFM----VSGTECEECFLTCHKRCLETLLILCGHRRLPAR 545
Query: 136 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 195
++ D L + + P VV C EIE R L +G+YRVSG +E + AF+
Sbjct: 546 TPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENG 605
Query: 196 GEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNAD--------- 246
++S N D++ + LK + ++L PVI + Y FI AK +AD
Sbjct: 606 RALVELSGNSPHDVSSV---LKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPS 662
Query: 247 ---ERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPP 303
E + ++ +L+ LP ++Y TLR+L+ HL +V +N M+A NLGIVFGPTL+RPP
Sbjct: 663 PSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPP 722
Query: 304 EDS------TLTTLHDMRYQKLIVQILIENEDVLF 332
+ +T L D +Q +V+ LI + + +F
Sbjct: 723 DGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIF 757
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 130 bits (328), Expect = 1e-30
Identities = 75/227 (33%), Positives = 121/227 (53%), Gaps = 24/227 (10%)
Query: 113 GLNVHKQCSKHVPN-------DCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREI 165
G+N+ K+ K P +CQP N + P++V C R +
Sbjct: 794 GINIIKKNKKAAPRAFGVRLEECQP-----------------ATENQRVPLIVAACCRIV 836
Query: 166 EARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPI 225
EARGL+S G+YRV G + ++ +R ++ + D+N+I+ LK +FR LP
Sbjct: 837 EARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDINLQDERWQDLNVISSLLKSFFRKLPE 896
Query: 226 PVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNF 285
P+ T D Y+ FI+A +I +A ER+ + +++ LP +YETL++L+ HLK + + + N
Sbjct: 897 PLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNK 956
Query: 286 MNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332
M NL +VFGPTL+R ED+ + M + IV+ LI++ D F
Sbjct: 957 MEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFF 1003
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 130 bits (328), Expect = 1e-30
Identities = 68/211 (32%), Positives = 123/211 (58%), Gaps = 9/211 (4%)
Query: 129 QPDLKRIKK-------VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGF 181
+P LK +++ ++ L + + N+ P V CI +E RGL +G+YRVSG
Sbjct: 262 RPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGN 321
Query: 182 TEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAK 241
I+ ++ +++ EK ++ + + DI+++TGALK++FR+LP P+ Y + +F++A K
Sbjct: 322 LATIQKLRFIVNQE-EKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIK 380
Query: 242 ISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMR 301
+ + R+EAV ++ LPP + +T++ L HL K+ N M+ ++LGIVFGPTL+R
Sbjct: 381 KQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLR 440
Query: 302 PPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332
++ +H M YQ I ++++ +F
Sbjct: 441 AENETGNMAIH-MVYQNQIAELMLSEYSKIF 470
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 130 bits (327), Expect = 2e-30
Identities = 70/202 (34%), Positives = 113/202 (55%), Gaps = 6/202 (2%)
Query: 136 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 195
++V+ CDL + P V+ C IEA G+ +G+YR+SG + +I+ ++ FD +
Sbjct: 310 QRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVV-DGIYRLSGVSSNIQRLRHEFDSE 368
Query: 196 GEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEV 255
DI+ ++ KLYFR+LP P++TY Y KF +A + +ERL VH+V
Sbjct: 369 RIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDV 428
Query: 256 LMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTL-----TT 310
+ LPP HY TL YL+ HL ++ + + M+A NL IV+ P L+R E ++
Sbjct: 429 IQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAA 488
Query: 311 LHDMRYQKLIVQILIENEDVLF 332
++R Q ++V+ L+ + DVLF
Sbjct: 489 FREVRVQSVVVEFLLTHVDVLF 510
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 130 bits (326), Expect = 2e-30
Identities = 68/178 (38%), Positives = 108/178 (60%), Gaps = 3/178 (1%)
Query: 157 VVDICIREIEARGLKSEGLYRVSGFTEHIEDV-KMAFD-RDGEKADISANVYPDINIITG 214
++ CI +E RG+ +GLYRV G + ++ + M D + + D+ + ++ IT
Sbjct: 398 IIRKCISAVETRGINDQGLYRVVGVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITS 457
Query: 215 ALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHL 274
ALK Y R LP P++TY+ + FI AK + + R+ A+H ++ LP + E L L+ HL
Sbjct: 458 ALKQYLRSLPEPLMTYELHGDFIVPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHL 517
Query: 275 KKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332
V+ + K N M NLG+VFGPTLMRP E+ T+ L D+++Q ++V+ILIEN + +F
Sbjct: 518 TNVSNHSKQNLMTVANLGVVFGPTLMRPQEE-TVAALMDLKFQNIVVEILIENHEKIF 574
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 129 bits (324), Expect = 4e-30
Identities = 88/290 (30%), Positives = 144/290 (49%), Gaps = 24/290 (8%)
Query: 48 PLKLFACSQISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGV 107
P+K + RA HN H F + P CE C +++W L+ + +
Sbjct: 1610 PVKQSKAQKKKRKQERAVQEHNG--------HVFASYQVSIPQSCEQCLSYIW-LMDKAL 1660
Query: 108 RCSDCGLNVHKQCSKHVPNDC--------QPDLKRIKKVYCCDLTTLVKAHNTQRPMVVD 159
CS C + HK+C + + C +P ++ C D T KA P+V++
Sbjct: 1661 LCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHFGVCVDSLTSDKA---SVPIVLE 1717
Query: 160 ICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLY 219
+ +E GL +EGLYR SG +++ A D A + +P I+ ITG LK +
Sbjct: 1718 KLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD--PAAVKLENFP-IHAITGVLKQW 1774
Query: 220 FRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTM 279
R+LP P++T+ Y F+ A ++ E+L A++ VL LP A++ +L L+ HL KV +
Sbjct: 1775 LRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVKVAL 1834
Query: 280 NEKDNFMNAENLGIVFGPTLMRPPEDS-TLTTLHDMRYQKLIVQILIENE 328
E N M+ L I+F P L+R P++S LT++ D+ V++LI+ +
Sbjct: 1835 LEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQ 1884
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 129 bits (324), Expect = 4e-30
Identities = 88/290 (30%), Positives = 144/290 (49%), Gaps = 24/290 (8%)
Query: 48 PLKLFACSQISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGV 107
P+K + RA HN H F + P CE C +++W L+ + +
Sbjct: 1610 PVKQSKAQKKKRKQERAVQEHNG--------HVFASYQVSIPQSCEQCLSYIW-LMDKAL 1660
Query: 108 RCSDCGLNVHKQCSKHVPNDC--------QPDLKRIKKVYCCDLTTLVKAHNTQRPMVVD 159
CS C + HK+C + + C +P ++ C D T KA P+V++
Sbjct: 1661 LCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHFGVCVDSLTSDKA---SVPIVLE 1717
Query: 160 ICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLY 219
+ +E GL +EGLYR SG +++ A D A + +P I+ ITG LK +
Sbjct: 1718 KLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTD--PAAVKLENFP-IHAITGVLKQW 1774
Query: 220 FRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTM 279
R+LP P++T+ Y F+ A ++ E+L A++ VL LP A++ +L L+ HL KV +
Sbjct: 1775 LRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVKVAL 1834
Query: 280 NEKDNFMNAENLGIVFGPTLMRPPEDS-TLTTLHDMRYQKLIVQILIENE 328
E N M+ L I+F P L+R P++S LT++ D+ V++LI+ +
Sbjct: 1835 LEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQ 1884
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 128 bits (322), Expect = 6e-30
Identities = 66/189 (34%), Positives = 120/189 (63%), Gaps = 3/189 (1%)
Query: 137 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 196
+V+ +L L + N P V +CI +E GL +G+YRVSG I+ ++ A + D
Sbjct: 652 QVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD- 710
Query: 197 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 256
EK D++ + + DI++ITGALK++FR+LP P+ T++ ++ F++A K +R+ AV +++
Sbjct: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIK-QEPRQRVAAVKDLI 769
Query: 257 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRY 316
LP + +T++ L HL++V N + N M +++ IVFGPTL++P +++ +H + Y
Sbjct: 770 RQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTV-Y 828
Query: 317 QKLIVQILI 325
Q IV++++
Sbjct: 829 QNQIVELIL 837
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 128 bits (321), Expect = 8e-30
Identities = 75/250 (30%), Positives = 127/250 (50%), Gaps = 8/250 (3%)
Query: 79 HNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQP--DLKRIK 136
H FK + P +CEYC++ +W + V C C HK+C C D +
Sbjct: 2000 HIFKATQYSIPTYCEYCSSLIWIMDRASV-CKLCKYACHKKCCLKTTAKCSKKYDPELSS 2058
Query: 137 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDG 196
+ + +L+ L T P+VV+ I IE GL +EG+YR SG T I++++ D D
Sbjct: 2059 RQFGVELSRLTSEDRTV-PLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDA 2117
Query: 197 EKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVL 256
E ++ +I++I K + RDLP P++T++ Y +F+ A + E + V+ V+
Sbjct: 2118 ESVNLDDY---NIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVI 2174
Query: 257 MLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDS-TLTTLHDMR 315
L H TL L+ HL ++ + E N M+A L IVF P ++R P+ + L ++ D+
Sbjct: 2175 DQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDIS 2234
Query: 316 YQKLIVQILI 325
V++++
Sbjct: 2235 KTTTCVELIV 2244
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 128 bits (321), Expect = 8e-30
Identities = 69/183 (37%), Positives = 105/183 (57%), Gaps = 13/183 (7%)
Query: 157 VVDICIREIEARGLKSEGLYRVSGFTEHIE-------DVKMAFDRDGEKADISANVYPDI 209
++ CI +E RG+ +GLYR+ G ++ D K A + + DI A +I
Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETE---TDICAEW--EI 446
Query: 210 NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY 269
IT ALK Y R LP P++ Y FI AAK+ N + R+ +H ++ LP + + L+
Sbjct: 447 KTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQL 506
Query: 270 LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED 329
LM HL V N K N M NLG+VFGPTL+RP E+ T+ + D+++Q ++++ILIEN +
Sbjct: 507 LMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEE-TVAAIMDIKFQNIVIEILIENHE 565
Query: 330 VLF 332
+F
Sbjct: 566 KIF 568
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 128 bits (321), Expect = 8e-30
Identities = 69/183 (37%), Positives = 105/183 (57%), Gaps = 13/183 (7%)
Query: 157 VVDICIREIEARGLKSEGLYRVSGFTEHIE-------DVKMAFDRDGEKADISANVYPDI 209
++ CI +E RG+ +GLYR+ G ++ D K A + + DI A +I
Sbjct: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETE---TDICAEW--EI 446
Query: 210 NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY 269
IT ALK Y R LP P++ Y FI AAK+ N + R+ +H ++ LP + + L+
Sbjct: 447 KTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQL 506
Query: 270 LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED 329
LM HL V N K N M NLG+VFGPTL+RP E+ T+ + D+++Q ++++ILIEN +
Sbjct: 507 LMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEE-TVAAIMDIKFQNIVIEILIENHE 565
Query: 330 VLF 332
+F
Sbjct: 566 KIF 568
>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
Length = 1136
Score = 127 bits (319), Expect = 1e-29
Identities = 89/282 (31%), Positives = 147/282 (52%), Gaps = 34/282 (12%)
Query: 77 KTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDC-QPDLKRI 135
+TH ++ R P C C ++++ QG C +C L HK+C + + C L+
Sbjct: 701 RTH--RLRKLRTPAKCRECNSYVY---FQGAECEECCLACHKKCLETLAIQCGHKKLQGR 755
Query: 136 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 195
+++ D + ++ P +V C+ EIE R L+++G+YRV+G +E + AF+
Sbjct: 756 LQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENG 815
Query: 196 GEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADE-------- 247
E ++S DI+ + LKLY R LP P+I++ Y + + AK S E
Sbjct: 816 KELVELSQASPHDISNV---LKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASR 872
Query: 248 ------RLEAV--------HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGI 293
EAV E+L LPP + +L+YL+ HL+++ E+DN M NLGI
Sbjct: 873 GRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGI 932
Query: 294 VFGPTLMRP-PEDST--LTTLHDMRYQKLIVQILIENEDVLF 332
VFGPTL+RP P ++T L++L D +Q +++ LI + ++F
Sbjct: 933 VFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVF 974
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 126 bits (316), Expect = 3e-29
Identities = 69/184 (37%), Positives = 112/184 (60%), Gaps = 4/184 (2%)
Query: 143 LTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADIS 202
LTT+V P+ ++ CI IEA GL +EG+YRVSG +E ++ FD+D D++
Sbjct: 1251 LTTVVTPEKPI-PIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQD-HNLDLA 1308
Query: 203 ANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPA 262
+ +N + GA+K +F +LP P++ Y+ ++A KI++ +++L A+ EVL P
Sbjct: 1309 EKDFT-VNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKE 1367
Query: 263 HYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQ 322
++E +Y++ HL KV+ N K N M +ENL I F PTLMR P+ ST+ L R + I++
Sbjct: 1368 NHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMR-PDFSTMDALTATRTYQTIIE 1426
Query: 323 ILIE 326
+ I+
Sbjct: 1427 LFIQ 1430
>gi|4505507 oligophrenin 1 [Homo sapiens]
Length = 802
Score = 123 bits (308), Expect = 3e-28
Identities = 67/168 (39%), Positives = 100/168 (59%), Gaps = 2/168 (1%)
Query: 161 CIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISA-NVYPDINIITGALKLY 219
CI IE +G+K+EGLYR G ++ + AF D+ N DI IT +LK Y
Sbjct: 393 CINIIETKGIKTEGLYRTVGSNIQVQKLLNAFFDPKCPGDVDFHNSDWDIKTITSSLKFY 452
Query: 220 FRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTM 279
R+L PV+TY + + + AAK N D RL A+H ++ LP + E L L+ HL V
Sbjct: 453 LRNLSEPVMTYRLHKELVSAAKSDNLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCE 512
Query: 280 NEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIEN 327
+ K+N M N+G++FGPTLMR ED T+ + ++++Q ++V+ILIE+
Sbjct: 513 HSKENLMTPSNMGVIFGPTLMRAQED-TVAAMMNIKFQNIVVEILIEH 559
>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
Length = 1502
Score = 122 bits (305), Expect = 6e-28
Identities = 67/172 (38%), Positives = 99/172 (57%), Gaps = 6/172 (3%)
Query: 155 PMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITG 214
P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S V +N + G
Sbjct: 1275 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1332
Query: 215 ALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHL 274
ALK +F DLP P+I Y + + ++AAKI + ERL A+ E++ P +Y+ RY++ HL
Sbjct: 1333 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1392
Query: 275 KKVTMNEKDNFMNAENLGIVFGPTLMRPP----EDSTLTTLHDMRYQKLIVQ 322
+V+ K N M A+NL I F PTLMRP E + T +H + I Q
Sbjct: 1393 NRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQ 1444
>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
Length = 1501
Score = 122 bits (305), Expect = 6e-28
Identities = 67/172 (38%), Positives = 99/172 (57%), Gaps = 6/172 (3%)
Query: 155 PMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITG 214
P+ V+ C+ IE GL +EGLYRVSG ++++ FD+D +S V +N + G
Sbjct: 1274 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEV--TVNAVAG 1331
Query: 215 ALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHL 274
ALK +F DLP P+I Y + + ++AAKI + ERL A+ E++ P +Y+ RY++ HL
Sbjct: 1332 ALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHL 1391
Query: 275 KKVTMNEKDNFMNAENLGIVFGPTLMRPP----EDSTLTTLHDMRYQKLIVQ 322
+V+ K N M A+NL I F PTLMRP E + T +H + I Q
Sbjct: 1392 NRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQ 1443
>gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]
Length = 1261
Score = 120 bits (301), Expect = 2e-27
Identities = 89/302 (29%), Positives = 141/302 (46%), Gaps = 47/302 (15%)
Query: 59 SLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHK 118
+L+ +AALTH K R P C C + + QGV C +C L H+
Sbjct: 604 TLMSKAALTH-------------KFRKLRSPTKCRDCEGIV---VFQGVECEECLLVCHR 647
Query: 119 QCSKHVPNDC-QPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYR 177
+C +++ C L ++ + T + K P ++ IC EIE R L +G+YR
Sbjct: 648 KCLENLVIICGHQKLPGKIHLFGAEFTQVAKKEPDGIPFILKICASEIENRALCLQGIYR 707
Query: 178 VSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFI 237
V G E + A + DIS DI LKLY R LP P I + Y +FI
Sbjct: 708 VCGNKIKTEKLCQALENGMHLVDISEFSSHDI---CDVLKLYLRQLPEPFILFRLYKEFI 764
Query: 238 DAAK-ISNADERLEAVH-----------------------EVLMLLPPAHYETLRYLMIH 273
D AK I + +E E ++L LP +++ +L +L++H
Sbjct: 765 DLAKEIQHVNEEQETKKNSLEDKKWPNMCIEINRILLKSKDLLRQLPASNFNSLHFLIVH 824
Query: 274 LKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDS---TLTTLHDMRYQKLIVQILIENEDV 330
LK+V + ++N MN++NLG++FGP+L+RP + T+++L + Q +V+ LI
Sbjct: 825 LKRVVDHAEENKMNSKNLGVIFGPSLIRPRPTTAPITISSLAEYSNQARLVEFLITYSQK 884
Query: 331 LF 332
+F
Sbjct: 885 IF 886
>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
Length = 2087
Score = 120 bits (300), Expect = 2e-27
Identities = 70/203 (34%), Positives = 112/203 (55%), Gaps = 8/203 (3%)
Query: 136 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 195
++V+ CDL + + P V+ C IE G+ +G+YR+SG +I+ ++ FD +
Sbjct: 367 ERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIV-DGIYRLSGVASNIQRLRHEFDSE 425
Query: 196 GEKADISANVY-PDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE 254
D++ Y DI+ + KLYFR+LP P++TY Y KF DA + +ERL +H+
Sbjct: 426 -HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHD 484
Query: 255 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE-----DSTLT 309
V+ LPP HY TL +LM HL + M+A+NL IV+ P L+R + S
Sbjct: 485 VIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTA 544
Query: 310 TLHDMRYQKLIVQILIENEDVLF 332
++R Q ++V+ ++ + DVLF
Sbjct: 545 AFMEVRIQSVVVEFILNHVDVLF 567
>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
Length = 1738
Score = 120 bits (300), Expect = 2e-27
Identities = 70/203 (34%), Positives = 112/203 (55%), Gaps = 8/203 (3%)
Query: 136 KKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRD 195
++V+ CDL + + P V+ C IE G+ +G+YR+SG +I+ ++ FD +
Sbjct: 18 ERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIV-DGIYRLSGVASNIQRLRHEFDSE 76
Query: 196 GEKADISANVY-PDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE 254
D++ Y DI+ + KLYFR+LP P++TY Y KF DA + +ERL +H+
Sbjct: 77 -HVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHD 135
Query: 255 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE-----DSTLT 309
V+ LPP HY TL +LM HL + M+A+NL IV+ P L+R + S
Sbjct: 136 VIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTA 195
Query: 310 TLHDMRYQKLIVQILIENEDVLF 332
++R Q ++V+ ++ + DVLF
Sbjct: 196 AFMEVRIQSVVVEFILNHVDVLF 218
>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
sapiens]
Length = 731
Score = 119 bits (299), Expect = 3e-27
Identities = 68/213 (31%), Positives = 116/213 (54%), Gaps = 18/213 (8%)
Query: 137 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 194
+V+ C L +L + P + +CI ++ RGL +G+YRVSG ++ ++ DR
Sbjct: 519 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 578
Query: 195 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDA 239
DG + D+ + + DI+++TGALKL+ R+LP P++ F A
Sbjct: 579 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAA 638
Query: 240 AKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 299
+S +++ L + E++ +P +++TLRYL+ HL +V + N M NLGIVFGPTL
Sbjct: 639 LALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTL 698
Query: 300 MRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332
RP ++++ H + Y +VQ+++ N LF
Sbjct: 699 FRPEQETSDPAAHAL-YPGQLVQLMLTNFTSLF 730
>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
sapiens]
Length = 547
Score = 119 bits (299), Expect = 3e-27
Identities = 68/213 (31%), Positives = 116/213 (54%), Gaps = 18/213 (8%)
Query: 137 KVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR-- 194
+V+ C L +L + P + +CI ++ RGL +G+YRVSG ++ ++ DR
Sbjct: 335 QVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRER 394
Query: 195 ----DGE-----------KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDA 239
DG + D+ + + DI+++TGALKL+ R+LP P++ F A
Sbjct: 395 AVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAA 454
Query: 240 AKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTL 299
+S +++ L + E++ +P +++TLRYL+ HL +V + N M NLGIVFGPTL
Sbjct: 455 LALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTL 514
Query: 300 MRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332
RP ++++ H + Y +VQ+++ N LF
Sbjct: 515 FRPEQETSDPAAHAL-YPGQLVQLMLTNFTSLF 546
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 118 bits (295), Expect = 8e-27
Identities = 66/206 (32%), Positives = 110/206 (53%), Gaps = 8/206 (3%)
Query: 133 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF 192
K + CDLT +++ P V+ C IE G+ +G+YR+SG T +I+ ++ F
Sbjct: 13 KGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIV-DGIYRLSGVTSNIQRLRQEF 71
Query: 193 DRDGEKADISANVY-PDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEA 251
D + D++ VY DI+ + KLYFR+LP P++TY+ Y KF +A + +L
Sbjct: 72 GSD-QCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLAR 130
Query: 252 VHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTL 311
+ V+ LPP+HY TL YL+ HL + M+A NL +V+ P L+R E
Sbjct: 131 IQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCN 190
Query: 312 HD-----MRYQKLIVQILIENEDVLF 332
D +R Q+++++ ++ + D +F
Sbjct: 191 GDAAFLAVRVQQVVIEFILNHVDQIF 216
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 117 bits (293), Expect = 1e-26
Identities = 62/167 (37%), Positives = 95/167 (56%), Gaps = 1/167 (0%)
Query: 138 VYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGE 197
V+ + + K ++ P +V C+ EIE RG++ G+YRVSG I+ +K AFD + +
Sbjct: 1007 VFGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNK 1066
Query: 198 KADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLM 257
+ + D+N I G LKLYFR+LP P+ T + Y F + +S+ + + +L+
Sbjct: 1067 DVSVMMSEM-DVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLL 1125
Query: 258 LLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE 304
LP A+ T +L+ HLK+V E N M+ NL VFGPTL+RP E
Sbjct: 1126 SLPEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSE 1172
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,649,430
Number of Sequences: 37866
Number of extensions: 538231
Number of successful extensions: 2230
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 1847
Number of HSP's gapped (non-prelim): 281
length of query: 332
length of database: 18,247,518
effective HSP length: 103
effective length of query: 229
effective length of database: 14,347,320
effective search space: 3285536280
effective search space used: 3285536280
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.