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Search of human proteins with 90819231
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|90819231 myeloid/lymphoid or mixed-lineage leukemia
(trithorax homolog, Drosophila); translocated to, 4 isoform 3 [Homo
sapiens]
(1612 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora... 3242 0.0
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 3179 0.0
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 3174 0.0
gi|148746189 multiple PDZ domain protein [Homo sapiens] 72 4e-12
gi|93204861 protein phosphatase 1, regulatory (inhibitor) subuni... 70 1e-11
gi|112382257 InaD-like [Homo sapiens] 69 3e-11
gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo ... 69 5e-11
gi|40254834 kinesin family member 1C [Homo sapiens] 68 8e-11
gi|87196343 PDZ domain containing 2 [Homo sapiens] 67 1e-10
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 66 3e-10
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i... 66 3e-10
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i... 66 3e-10
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is... 66 3e-10
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 64 2e-09
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 64 2e-09
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 64 2e-09
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 63 2e-09
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 62 4e-09
gi|148833504 interleukin 16 isoform 2 [Homo sapiens] 62 6e-09
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 62 6e-09
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 62 6e-09
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 61 8e-09
gi|63999048 syntaxin binding protein 4 [Homo sapiens] 60 2e-08
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 60 2e-08
gi|7661878 kinesin family member 14 [Homo sapiens] 60 2e-08
gi|148612825 Rap GTPase interactor [Homo sapiens] 59 4e-08
gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens] 59 4e-08
gi|119120907 par-3 partitioning defective 3 homolog B isoform a ... 59 4e-08
gi|119120903 par-3 partitioning defective 3 homolog B isoform c ... 59 4e-08
gi|45827729 scribble isoform b [Homo sapiens] 59 5e-08
>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 3 [Homo
sapiens]
Length = 1612
Score = 3242 bits (8406), Expect = 0.0
Identities = 1612/1612 (100%), Positives = 1612/1612 (100%)
Query: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI
Sbjct: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
Query: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD
Sbjct: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
Query: 121 DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS 180
DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS
Sbjct: 121 DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS 180
Query: 181 DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD 240
DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD
Sbjct: 181 DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD 240
Query: 241 GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM 300
GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM
Sbjct: 241 GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM 300
Query: 301 LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG 360
LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG
Sbjct: 301 LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG 360
Query: 361 KTPKGKERADGSGYGSTLPPEKLPYLVELSPDGSDSRDKPKLYRLQLSVTEVGTEKLDDN 420
KTPKGKERADGSGYGSTLPPEKLPYLVELSPDGSDSRDKPKLYRLQLSVTEVGTEKLDDN
Sbjct: 361 KTPKGKERADGSGYGSTLPPEKLPYLVELSPDGSDSRDKPKLYRLQLSVTEVGTEKLDDN 420
Query: 421 SIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETTMLQSGMKVQFGASHV 480
SIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETTMLQSGMKVQFGASHV
Sbjct: 421 SIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETTMLQSGMKVQFGASHV 480
Query: 481 FKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIHSGTALPTSKSTTRLD 540
FKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIHSGTALPTSKSTTRLD
Sbjct: 481 FKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIHSGTALPTSKSTTRLD 540
Query: 541 SDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELILPASIEFRESSEDSFL 600
SDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELILPASIEFRESSEDSFL
Sbjct: 541 SDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELILPASIEFRESSEDSFL 600
Query: 601 SAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTHKVIAVVNKMVSMMEG 660
SAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTHKVIAVVNKMVSMMEG
Sbjct: 601 SAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTHKVIAVVNKMVSMMEG 660
Query: 661 VIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAHLVQMAFKYLVHCLQS 720
VIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAHLVQMAFKYLVHCLQS
Sbjct: 661 VIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAHLVQMAFKYLVHCLQS 720
Query: 721 ELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAALTIQLFSQLFHFINM 780
ELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAALTIQLFSQLFHFINM
Sbjct: 721 ELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAALTIQLFSQLFHFINM 780
Query: 781 WLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADCHLSRIVQATTLLTMD 840
WLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADCHLSRIVQATTLLTMD
Sbjct: 781 WLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADCHLSRIVQATTLLTMD 840
Query: 841 KYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIENVVTVAENTADELARS 900
KYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIENVVTVAENTADELARS
Sbjct: 841 KYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIENVVTVAENTADELARS 900
Query: 901 DGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQRGFCRLIPHTRSPGT 960
DGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQRGFCRLIPHTRSPGT
Sbjct: 901 DGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQRGFCRLIPHTRSPGT 960
Query: 961 WTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIY 1020
WTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIY
Sbjct: 961 WTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIY 1020
Query: 1021 VKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIY 1080
VKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIY
Sbjct: 1021 VKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIY 1080
Query: 1081 HGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLPWAEYSEPKK 1140
HGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLPWAEYSEPKK
Sbjct: 1081 HGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLPWAEYSEPKK 1140
Query: 1141 LPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRP 1200
LPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRP
Sbjct: 1141 LPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVSTGNLCTEEQTPPPRP 1200
Query: 1201 EAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQ 1260
EAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQ
Sbjct: 1201 EAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTRSQ 1260
Query: 1261 EELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSKSVTPASTLT 1320
EELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSKSVTPASTLT
Sbjct: 1261 EELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSKSVTPASTLT 1320
Query: 1321 KSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQ 1380
KSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQ
Sbjct: 1321 KSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQ 1380
Query: 1381 IGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSP 1440
IGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSP
Sbjct: 1381 IGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSP 1440
Query: 1441 LTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPW 1500
LTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPW
Sbjct: 1441 LTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPW 1500
Query: 1501 KRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQK 1560
KRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQK
Sbjct: 1501 KRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQK 1560
Query: 1561 DEDDEEEEDDDVDTMLIMQRLEAERRARVKGGVLWLCPSVVPILASACFPWG 1612
DEDDEEEEDDDVDTMLIMQRLEAERRARVKGGVLWLCPSVVPILASACFPWG
Sbjct: 1561 DEDDEEEEDDDVDTMLIMQRLEAERRARVKGGVLWLCPSVVPILASACFPWG 1612
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 3179 bits (8242), Expect = 0.0
Identities = 1588/1603 (99%), Positives = 1588/1603 (99%), Gaps = 15/1603 (0%)
Query: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI
Sbjct: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
Query: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD
Sbjct: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
Query: 121 DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS 180
DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS
Sbjct: 121 DREGRFVLKNENDAIPPKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQAS 180
Query: 181 DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD 240
DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD
Sbjct: 181 DKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSD 240
Query: 241 GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM 300
GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM
Sbjct: 241 GRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVM 300
Query: 301 LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG 360
LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG
Sbjct: 301 LPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEG 360
Query: 361 KTPKGKERADGSGYGSTLPPEKLPYLVELSP---------------DGSDSRDKPKLYRL 405
KTPKGKERADGSGYGSTLPPEKLPYLVELSP DGSDSRDKPKLYRL
Sbjct: 361 KTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYRL 420
Query: 406 QLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETT 465
QLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETT
Sbjct: 421 QLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETT 480
Query: 466 MLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIH 525
MLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIH
Sbjct: 481 MLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIH 540
Query: 526 SGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELIL 585
SGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELIL
Sbjct: 541 SGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELIL 600
Query: 586 PASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTH 645
PASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTH
Sbjct: 601 PASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTH 660
Query: 646 KVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAH 705
KVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAH
Sbjct: 661 KVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAH 720
Query: 706 LVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAA 765
LVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAA
Sbjct: 721 LVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAA 780
Query: 766 LTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADC 825
LTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADC
Sbjct: 781 LTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADC 840
Query: 826 HLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIEN 885
HLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIEN
Sbjct: 841 HLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIEN 900
Query: 886 VVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQ 945
VVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQ
Sbjct: 901 VVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQ 960
Query: 946 RGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLS 1005
RGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLS
Sbjct: 961 RGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLS 1020
Query: 1006 IVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRT 1065
IVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRT
Sbjct: 1021 IVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRT 1080
Query: 1066 SSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSP 1125
SSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSP
Sbjct: 1081 SSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSP 1140
Query: 1126 ESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVS 1185
ESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVS
Sbjct: 1141 ESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSVS 1200
Query: 1186 TGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTD 1245
TGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTD
Sbjct: 1201 TGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHTD 1260
Query: 1246 SNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEH 1305
SNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEH
Sbjct: 1261 SNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEH 1320
Query: 1306 LNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDG 1365
LNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDG
Sbjct: 1321 LNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDG 1380
Query: 1366 MSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKL 1425
MSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKL
Sbjct: 1381 MSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKL 1440
Query: 1426 GQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVS 1485
GQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVS
Sbjct: 1441 GQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVS 1500
Query: 1486 KEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLM 1545
KEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLM
Sbjct: 1501 KEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLM 1560
Query: 1546 LEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR 1588
LEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR
Sbjct: 1561 LEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR 1603
Score = 31.2 bits (69), Expect = 8.5
Identities = 28/109 (25%), Positives = 44/109 (40%), Gaps = 6/109 (5%)
Query: 1392 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQ-----MRTQSLNPAPFSPLTAQQM 1446
E RKRE R ++E+ R +EE ER +R+ E K Q R ++ + +
Sbjct: 1628 EMRKREAEDRARQEEERRRQEE-ERTKRDAEEKRRQEEGYYSRLEAERRRQHDEAARRLL 1686
Query: 1447 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSL 1495
+PE P + P P P + + K ++ S DSL
Sbjct: 1687 EPEAPGLCRPPLPRDYEPPSPSPAPGAPPPPPQRNASYLKTQVLSPDSL 1735
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 3174 bits (8230), Expect = 0.0
Identities = 1588/1604 (99%), Positives = 1588/1604 (99%), Gaps = 16/1604 (0%)
Query: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI
Sbjct: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
Query: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD
Sbjct: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
Query: 121 DREGRFVLKNENDAIPPK-AQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA 179
DREGRFVLKNENDAIPPK AQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA
Sbjct: 121 DREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA 180
Query: 180 SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS 239
SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS
Sbjct: 181 SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS 240
Query: 240 DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV 299
DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV
Sbjct: 241 DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV 300
Query: 300 MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE 359
MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE
Sbjct: 301 MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE 360
Query: 360 GKTPKGKERADGSGYGSTLPPEKLPYLVELSP---------------DGSDSRDKPKLYR 404
GKTPKGKERADGSGYGSTLPPEKLPYLVELSP DGSDSRDKPKLYR
Sbjct: 361 GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR 420
Query: 405 LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET 464
LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET
Sbjct: 421 LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET 480
Query: 465 TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI 524
TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI
Sbjct: 481 TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI 540
Query: 525 HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI 584
HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI
Sbjct: 541 HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI 600
Query: 585 LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT 644
LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT
Sbjct: 601 LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT 660
Query: 645 HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA 704
HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA
Sbjct: 661 HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA 720
Query: 705 HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA 764
HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA
Sbjct: 721 HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA 780
Query: 765 ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD 824
ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD
Sbjct: 781 ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD 840
Query: 825 CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE 884
CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE
Sbjct: 841 CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE 900
Query: 885 NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC 944
NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC
Sbjct: 901 NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC 960
Query: 945 QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL 1004
QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL
Sbjct: 961 QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL 1020
Query: 1005 SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR 1064
SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR
Sbjct: 1021 SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR 1080
Query: 1065 TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS 1124
TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS
Sbjct: 1081 TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS 1140
Query: 1125 PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV 1184
PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV
Sbjct: 1141 PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV 1200
Query: 1185 STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT 1244
STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT
Sbjct: 1201 STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT 1260
Query: 1245 DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE 1304
DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE
Sbjct: 1261 DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE 1320
Query: 1305 HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD 1364
HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD
Sbjct: 1321 HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD 1380
Query: 1365 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1424
GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK
Sbjct: 1381 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1440
Query: 1425 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1484
LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV
Sbjct: 1441 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1500
Query: 1485 SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL 1544
SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL
Sbjct: 1501 SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL 1560
Query: 1545 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR 1588
MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR
Sbjct: 1561 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR 1604
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 72.0 bits (175), Expect = 4e-12
Identities = 44/121 (36%), Positives = 67/121 (55%), Gaps = 9/121 (7%)
Query: 954 HTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKK-QNGMGLSIVAAKGA 1012
H + P + ++ F G S + Q P+ ++TL++ +G+G SIV G+
Sbjct: 1927 HQQEPASSSLSFTGLTSSS--------IFQDDLGPPQCKSITLERGPDGLGFSIVGGYGS 1978
Query: 1013 GQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLE 1072
L IYVK+V GAA DGRL GDQ+++V+G+SL G++ E A ++ RT VTL
Sbjct: 1979 PHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLM 2038
Query: 1073 V 1073
V
Sbjct: 2039 V 2039
Score = 64.7 bits (156), Expect = 7e-10
Identities = 37/94 (39%), Positives = 54/94 (57%), Gaps = 4/94 (4%)
Query: 987 KEPEIITVTLKKQNGMGLSIVAAKGAGQDKL---GIYVKSVVKGGAADVDGRLAAGDQLL 1043
+E E V L K N GL I A G KL GI+VKS+ K A + DGR+ GDQ++
Sbjct: 371 EESETFDVELTK-NVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQIGDQII 429
Query: 1044 SVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQG 1077
+VDG +L G + ++A E++ T V L + ++G
Sbjct: 430 AVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRG 463
Score = 59.3 bits (142), Expect = 3e-08
Identities = 34/81 (41%), Positives = 50/81 (61%), Gaps = 9/81 (11%)
Query: 987 KEPEI---ITVTLKKQ--NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQ 1041
KE E+ +T+ L+K+ G+GLSIV + + G++V +VKGG AD DGRL GDQ
Sbjct: 1716 KEEEVCDTLTIELQKKPGKGLGLSIVGKR----NDTGVFVSDIVKGGIADADGRLMQGDQ 1771
Query: 1042 LLSVDGRSLVGLSQERAAELM 1062
+L V+G + +QE A L+
Sbjct: 1772 ILMVNGEDVRNATQEAVAALL 1792
Score = 54.3 bits (129), Expect = 9e-07
Identities = 28/80 (35%), Positives = 47/80 (58%), Gaps = 6/80 (7%)
Query: 1000 NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAA 1059
+G+G I+ K G + VK+++ GG AD GRL +GD +L + L G+S E+ A
Sbjct: 265 SGLGFGIIGGKATG-----VIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVA 319
Query: 1060 ELMTRTSSVVTLEVAKQGAI 1079
+++ + + V L +A+ GAI
Sbjct: 320 QVLRQCGNRVKLMIAR-GAI 338
Score = 52.0 bits (123), Expect = 5e-06
Identities = 50/188 (26%), Positives = 81/188 (43%), Gaps = 35/188 (18%)
Query: 966 EGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAG------QDKLGI 1019
EG ES L +NT + +P + + + +G+SIV +G G + GI
Sbjct: 1130 EGEGEESEL--QNTAYSN--WNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGI 1185
Query: 1020 YVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAI 1079
++K V++ A +G L GD+++ VDG L S E+A E + + + V V
Sbjct: 1186 FIKHVLEDSPAGKNGTLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMV------ 1239
Query: 1080 YHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQL-----PWAE 1134
+++N+P R S P + YN S+ N +S Q+ P
Sbjct: 1240 ----QSIINRP----------RKSPLPSLLHNLYPKYNFSSTNPFADSLQINADKAPSQS 1285
Query: 1135 YSEPKKLP 1142
SEP+K P
Sbjct: 1286 ESEPEKAP 1293
Score = 51.6 bits (122), Expect = 6e-06
Identities = 24/87 (27%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Query: 990 EIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRS 1049
E+ + G+G S+V + + +LGI+V+ + +G A DGRL DQ+L+++G++
Sbjct: 136 EVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDGRLKETDQILAINGQA 195
Query: 1050 L-VGLSQERAAELMTRTSSVVTLEVAK 1075
L ++ ++A ++ + V L +A+
Sbjct: 196 LDQTITHQQAISILQKAKDTVQLVIAR 222
Score = 51.6 bits (122), Expect = 6e-06
Identities = 35/108 (32%), Positives = 61/108 (56%), Gaps = 9/108 (8%)
Query: 966 EGADY--ESHLLRENTE--LAQPLRKEPEIITVTLKKQNG-MGLSIVAAKGAGQDKLGIY 1020
+G++Y E L N E + Q + KE T+ + K N +G+++ A K D LG+
Sbjct: 977 KGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGMTVSANK----DGLGMI 1032
Query: 1021 VKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSV 1068
V+S++ GGA DGR+A GD +LS++ S + ++ +A ++ R S +
Sbjct: 1033 VRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1080
Score = 49.7 bits (117), Expect = 2e-05
Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 22/131 (16%)
Query: 997 KKQNGMGLSIVAAKGAGQDKL-GIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQ 1055
K Q G+G++I + +D L G+ +KS+ + G A DGRL GDQ+L+VD +VG
Sbjct: 1488 KDQGGLGIAI-----SEEDTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPI 1542
Query: 1056 ERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFEL 1115
E+ L+ V L + + +P Q + G+ K+ L
Sbjct: 1543 EKFISLLKTAKMTVKLTI--------------HAENPDSQAVPSAAGAASGEKKNSSQSL 1588
Query: 1116 YNNSTQNGSPE 1126
Q+GSPE
Sbjct: 1589 M--VPQSGSPE 1597
Score = 47.4 bits (111), Expect = 1e-04
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 6/86 (6%)
Query: 997 KKQNGMGLSIVAAKGAGQDKL--GIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLS 1054
K + G+GLSIV G D L I + V + GAA DGRL AGDQ+L V+G L +
Sbjct: 1634 KGRTGLGLSIVG----GSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKAT 1689
Query: 1055 QERAAELMTRTSSVVTLEVAKQGAIY 1080
+ A ++ +T V L + + A Y
Sbjct: 1690 HDEAINVLRQTPQRVRLTLYRDEAPY 1715
Score = 45.4 bits (106), Expect = 4e-04
Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 2/75 (2%)
Query: 997 KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQE 1056
K +G+GLS+ K + ++ +++ + GAA DGRL D+LL ++G+ L G S +
Sbjct: 1355 KGHSGLGLSLAGNKD--RSRMSVFIVGIDPNGAAGKDGRLQIADELLEINGQILYGRSHQ 1412
Query: 1057 RAAELMTRTSSVVTL 1071
A+ ++ S V +
Sbjct: 1413 NASSIIKCAPSKVKI 1427
Score = 40.8 bits (94), Expect = 0.011
Identities = 32/85 (37%), Positives = 44/85 (51%), Gaps = 10/85 (11%)
Query: 997 KKQNGMGLSIVAAKGAGQDKLG-----IYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLV 1051
K G+G SI+ QD + I ++S+V GG A+ DGRL GD+L+ V+ +L
Sbjct: 705 KGSKGLGFSILDY----QDPIDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLE 760
Query: 1052 GLSQERAAE-LMTRTSSVVTLEVAK 1075
S E A E L S V + VAK
Sbjct: 761 NSSLEEAVEALKGAPSGTVRIGVAK 785
Score = 39.7 bits (91), Expect = 0.024
Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Query: 993 TVTLKK--QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSL 1050
TV +KK + +G+SI G+ + I++ + G A +L GD+++++ G S
Sbjct: 1833 TVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTST 1892
Query: 1051 VGLSQERAAELMTRTSSVVTLEVAKQGAI 1079
G++ +A L+ S + ++V G +
Sbjct: 1893 EGMTHTQAVNLLKNASGSIEMQVVAGGDV 1921
Score = 37.0 bits (84), Expect = 0.15
Identities = 23/85 (27%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 990 EIITVTLKK---QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVD 1046
EI+ + K +G+G+S+ A G +++SV+ G G+L +GD+LL V+
Sbjct: 550 EIVVAHVSKFSENSGLGISLEATVGHH------FIRSVLPEGPVGHSGKLFSGDELLEVN 603
Query: 1047 GRSLVGLSQERAAELMTRTSSVVTL 1071
G +L+G + + ++ VT+
Sbjct: 604 GITLLGENHQDVVNILKELPIEVTM 628
>gi|93204861 protein phosphatase 1, regulatory (inhibitor) subunit 9A
[Homo sapiens]
Length = 1098
Score = 70.5 bits (171), Expect = 1e-11
Identities = 38/91 (41%), Positives = 59/91 (64%), Gaps = 4/91 (4%)
Query: 990 EIITVTLKK-QNGMGLSIVA---AKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
E+ V L+K ++G+G+SI+ AG +KLGI+VK+V +GGAA DGR+ DQ++ V
Sbjct: 501 ELFPVELEKDEDGLGISIIGMGVGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQIVEV 560
Query: 1046 DGRSLVGLSQERAAELMTRTSSVVTLEVAKQ 1076
DG SLVG++Q AA ++ T V + ++
Sbjct: 561 DGISLVGVTQNFAATVLRNTKGNVRFVIGRE 591
Score = 33.5 bits (75), Expect = 1.7
Identities = 50/227 (22%), Positives = 92/227 (40%), Gaps = 20/227 (8%)
Query: 1375 PPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQS-- 1432
P +++ +Q ERR+RE ++ Y + A +E E E+E ++G + S
Sbjct: 593 PGQVSEVAQLISQTLEQERRQRELLEQHYAQYDADDDETGEYATDEEEDEVGPVLPGSDM 652
Query: 1433 --------LNPAPFSPLTAQQMK-PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYIT 1483
N FSP K K LQ E+Q + +
Sbjct: 653 AIEVFELPENEDMFSPSELDTSKLSHKFKELQIKHAVTEAEIQKLKTKLQAAENEKVRWE 712
Query: 1484 VSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRK 1543
+ K +L + + + +E Q H V ++ ++E QS+ ++ ++ +K
Sbjct: 713 LEKTQLQQNIEENKERMLKLESYWIEAQTLCHTV---NEHLKETQSQYQALEKKYNKAKK 769
Query: 1544 LMLEWQ-----FQKRLQESKQKDEDDEEEEDDDVDTMLIMQR-LEAE 1584
L+ ++Q F KR + ++K ED E+ +V + + R LEAE
Sbjct: 770 LIKDFQQKELDFIKRQEAERKKIEDLEKAHLVEVQGLQVRIRDLEAE 816
>gi|112382257 InaD-like [Homo sapiens]
Length = 1801
Score = 69.3 bits (168), Expect = 3e-11
Identities = 37/88 (42%), Positives = 54/88 (61%), Gaps = 6/88 (6%)
Query: 990 EIITVTLKKQ--NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDG 1047
EI V L+K+ G+GLSIV + G+++ +VKGGAAD+DGRL GDQ+LSV+G
Sbjct: 1530 EIFPVDLQKKAGRGLGLSIVGKRNGS----GVFISDIVKGGAADLDGRLIQGDQILSVNG 1585
Query: 1048 RSLVGLSQERAAELMTRTSSVVTLEVAK 1075
+ SQE A ++ +V LE+ +
Sbjct: 1586 EDMRNASQETVATILKCAQGLVQLEIGR 1613
Score = 54.7 bits (130), Expect = 7e-07
Identities = 27/79 (34%), Positives = 47/79 (59%), Gaps = 5/79 (6%)
Query: 1000 NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAA 1059
+G+G IV K +G + V+++V GG AD DGRL GD +L + G ++ G++ E+ A
Sbjct: 256 SGLGFGIVGGKTSG-----VVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVA 310
Query: 1060 ELMTRTSSVVTLEVAKQGA 1078
+++ + V + VA+ A
Sbjct: 311 QVLRNCGNSVRMLVARDPA 329
Score = 54.7 bits (130), Expect = 7e-07
Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 26/163 (15%)
Query: 997 KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQE 1056
K +NG+GLS+ K + ++ I+V + G A DGR+ GD+LL ++ + L G S +
Sbjct: 1244 KDKNGLGLSLAGNKD--RSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGRSHQ 1301
Query: 1057 RAAELM-TRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSG----------- 1104
A+ ++ T S V + + + A+ T PS I D+ G+
Sbjct: 1302 NASAIIKTAPSKVKLVFIRNEDAVNQMAVTPFPVPSSSPSSIEDQSGTEPISSEEDGSVE 1361
Query: 1105 ---KPRPKSEGFEL---------YNNSTQNGSPESPQLPWAEY 1135
K P+SE F+L Y S E P P + Y
Sbjct: 1362 VGIKQLPESESFKLAVSQMKQQKYPTKVSFSSQEIPLAPASSY 1404
Score = 53.9 bits (128), Expect = 1e-06
Identities = 43/130 (33%), Positives = 60/130 (46%), Gaps = 11/130 (8%)
Query: 984 PLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLL 1043
P+ E+I K ++G+GLSIV K + I + V + GAA DGRL AGDQ+L
Sbjct: 1429 PIVPGQEMIIEISKGRSGLGLSIVGGKDTPLN--AIVIHEVYEEGAAARDGRLWAGDQIL 1486
Query: 1044 SVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQR------- 1096
V+G L S E A + +T V L V + A Y L P + ++
Sbjct: 1487 EVNGVDLRNSSHEEAITALRQTPQKVRLVVYRDEAHYRDEENLEIFPVDLQKKAGRGLGL 1546
Query: 1097 --ISDRRGSG 1104
+ R GSG
Sbjct: 1547 SIVGKRNGSG 1556
Score = 51.6 bits (122), Expect = 6e-06
Identities = 35/117 (29%), Positives = 60/117 (51%), Gaps = 7/117 (5%)
Query: 961 WTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIY 1020
WT D+ S + ++AQ ++ E I + G+G S+VA + K+ I+
Sbjct: 110 WTPKLGNEDFNSVI----QQMAQG--RQIEYIDIERPSTGGLGFSVVALRSQNLGKVDIF 163
Query: 1021 VKSVVKGGAADVDGRLAAGDQLLSVDGRSL-VGLSQERAAELMTRTSSVVTLEVAKQ 1076
VK V G AD D RL DQ+L+++ L +S ++A L+ +T+ + L VA++
Sbjct: 164 VKDVQPGSVADRDQRLKENDQILAINHTPLDQNISHQQAIALLQQTTGSLRLIVARE 220
Score = 47.4 bits (111), Expect = 1e-04
Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
Query: 990 EIITVTLKKQNG--MGLSIVAAKGAGQ--DKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
E V L +++G +G+ IV G + GIYVKS++ G AA +G + D++++V
Sbjct: 362 ETYNVELVRKDGQSLGIRIVGYVGTSHTGEASGIYVKSIIPGSAAYHNGHIQVNDKIVAV 421
Query: 1046 DGRSLVGLSQERAAELMTRTSSVVTLEVAKQ 1076
DG ++ G + E++ VV L + ++
Sbjct: 422 DGVNIQGFANHDVVEVLRNAGQVVHLTLVRR 452
Score = 44.3 bits (103), Expect = 0.001
Identities = 20/86 (23%), Positives = 43/86 (50%)
Query: 988 EPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDG 1047
EP + + + + +G+SI +G+ + +++ + G A +L GD+++S++G
Sbjct: 1673 EPRTVEINRELSDALGISIAGGRGSPLGDIPVFIAMIQASGVAARTQKLKVGDRIVSING 1732
Query: 1048 RSLVGLSQERAAELMTRTSSVVTLEV 1073
+ L GLS L+ + L+V
Sbjct: 1733 QPLDGLSHADVVNLLKNAYGRIILQV 1758
Score = 40.0 bits (92), Expect = 0.018
Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 14/135 (10%)
Query: 989 PEIITVTLKKQNGMGLSIVAAKGA------GQDKLGIYVKSVVKGGAADVDGRLAAGDQL 1042
P I+ + + +G+SIV + G++ GI++K V++ A L GD++
Sbjct: 1066 PRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKI 1125
Query: 1043 LSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAI------YHGLATLL--NQPSPMM 1094
L V G L S A E + + V V + H A + NQ
Sbjct: 1126 LEVSGVDLQNASHSEAVEAIKNAGNPVVFIVQSLSSTPRVIPNVHNKANKITGNQNQDTQ 1185
Query: 1095 QRISDRRGSGKPRPK 1109
++ R+G+ P K
Sbjct: 1186 EKKEKRQGTAPPPMK 1200
Score = 39.3 bits (90), Expect = 0.031
Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 13/108 (12%)
Query: 967 GADYESHLLRENTELAQP--LRKEPEIITV-TLKKQNGMGLSIVAAKGAGQDKLGIYVKS 1023
G DYE + +T++A L+K +++ + TL+ +G+ + + G Y+ S
Sbjct: 536 GPDYEVMVATLDTQIADDAELQKYSKLLPIHTLR----LGVEVDSFDGHH------YISS 585
Query: 1024 VVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTL 1071
+V GG D G L D+LL V+G L G S+ A + TL
Sbjct: 586 IVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTL 633
>gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo
sapiens]
Length = 817
Score = 68.6 bits (166), Expect = 5e-11
Identities = 68/213 (31%), Positives = 102/213 (47%), Gaps = 25/213 (11%)
Query: 875 EPFIPTDLIENVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPN 934
E F DL++ V+ ++ A S E +++ D + P+ PE G IP
Sbjct: 385 EDFSEADLVD--VSAYSGLGEDSAGSALEEDDEDDEEDGEPPYE-PESGCV-----EIP- 435
Query: 935 GLQEFLDPLCQRGFCRLIPHTRSPGTWTIYFEGADYESHL-----LRENTELAQPLRKEP 989
GL E DP R I + +P + DY+ + + E R E
Sbjct: 436 GLSEEEDPAPSRK----IHFSTAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVER 491
Query: 990 -EIITVTLKKQN-GMGLSIVAAKGAGQD----KLGIYVKSVVKGGAADVDGRLAAGDQLL 1043
E+ V L+K + G+G+SI+ GAG D KLGI+VK+V +GGAA DGR+ D L+
Sbjct: 492 LELFPVELEKDSEGLGISIIGM-GAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLV 550
Query: 1044 SVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQ 1076
VDG SLVG++Q AA ++ T V + ++
Sbjct: 551 EVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRE 583
Score = 35.8 bits (81), Expect = 0.34
Identities = 73/338 (21%), Positives = 117/338 (34%), Gaps = 27/338 (7%)
Query: 1264 REDKAYQLERHRIEAAMDRKSDSDMWINQSSS----LDSSTSSQEHLNHSSKSVTPASTL 1319
+E A +L R DRK D + N S+ LD+ S ++ S A +
Sbjct: 163 KEAAARRLLRQERAGLQDRKLDVVVRFNGSTEALDKLDADAVSPT-VSQLSAVFEKADSR 221
Query: 1320 T--KSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPS 1377
T GPG + VS+ R PPPPPPP +GD P P
Sbjct: 222 TGLHRGPGLPRAAGVPQVNSKLVSKRSRVFQPPPPPPPAP--SGDAPAEKERCPAGQQPP 279
Query: 1378 ANQIGLPSAQVAAAERRK----REEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSL 1433
+++ E RK E E E A E + + G +
Sbjct: 280 QHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQAEVTVHAALENGSTVATAA 339
Query: 1434 NPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTI-ERRDLQYITVSKEELSSG 1492
+PAP P AQ ++ + + P+ V P P + E + + ++S+
Sbjct: 340 SPAPEEP-KAQAAPEKEAAAVAPPERGVGNGRAPDVAPEEVDESKKEDFSEADLVDVSAY 398
Query: 1493 DSLSPD----PWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEW 1548
L D + D ++ E + + + EI L + D + RK+
Sbjct: 399 SGLGEDSAGSALEEDDEDDEEDGEPPYEPESGCVEIPGLSEEEDPAPS-----RKIHFS- 452
Query: 1549 QFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERR 1586
+Q +D + ++DVD M E E+R
Sbjct: 453 --TAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKR 488
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 67.8 bits (164), Expect = 8e-11
Identities = 49/134 (36%), Positives = 70/134 (52%), Gaps = 10/134 (7%)
Query: 368 RADGSGYGSTLPPEKLPYLVELSPDGSDSRDKPKLYRLQLSVTEVGTEKLDDNSIQLFGP 427
R DG G P+K P+LV L+ D S + LY ++ VT VG +D I+L G
Sbjct: 484 REDGGTVG-VFSPKKTPHLVNLNEDPLMS--ECLLYHIKDGVTRVGQVDMD---IKLTGQ 537
Query: 428 GIQPHHC---DLTNMDGVVTVTPRSMD-AETYVEGQRISETTMLQSGMKVQFGASHVFKF 483
I+ HC + DG V VT + AETYV G+ ++E +L+SG ++ G +HVF+F
Sbjct: 538 FIREQHCLFRSIPQPDGEVVVTLEPCEGAETYVNGKLVTEPLVLKSGNRIVMGKNHVFRF 597
Query: 484 VDPSQDHALAKRSV 497
P Q +R V
Sbjct: 598 NHPEQARLERERGV 611
>gi|87196343 PDZ domain containing 2 [Homo sapiens]
Length = 2839
Score = 67.4 bits (163), Expect = 1e-10
Identities = 74/287 (25%), Positives = 120/287 (41%), Gaps = 33/287 (11%)
Query: 890 AENTADELARSDGREV------QLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPL 943
A +E S G EV +LE PD +L +G+ + N P+ L+E P
Sbjct: 227 ANKAPEESKGSAGCEVSSDPSTELENGPDPELG-----NGHVFQL-ENGPDSLKEVAGPH 280
Query: 944 CQR-----GFCRLIPHTRSPGTWTI----YFEGA--DYESHLLRENTELAQPLRKEPEII 992
+R G IP T +P T + + +G D++S E+ + + E
Sbjct: 281 LERSEVDRGTEHRIPKTDAPLTTSNDKRRFSKGGKTDFQSSDCLAREEVGRIWKME---- 336
Query: 993 TVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVG 1052
LK+ +G+G+ + +G+ + I V V +GGAA DGRL+ GD+LL ++G LVG
Sbjct: 337 --LLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVG 394
Query: 1053 LSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEG 1112
LS E A ++ + +V L VA + L L ++ P + + S E
Sbjct: 395 LSHEEAVAILRSATGMVQLVVASKENSAEDLLRLTSKSLPDLTSSVEDVSSWTDNEDQEA 454
Query: 1113 FELYNNSTQNGSPESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPN 1159
+ G+ S Q EP+ + G + N + N
Sbjct: 455 ----DGEEDEGTSSSVQRAMPGTDEPQDVCGAEESKGNLESPKQGSN 497
Score = 52.8 bits (125), Expect = 3e-06
Identities = 30/101 (29%), Positives = 55/101 (54%), Gaps = 10/101 (9%)
Query: 968 ADYESHLLRENTELAQPLRKE-------PEIITVT---LKKQNGMGLSIVAAKGAGQDKL 1017
A E H+++++T + E P +I++ +K G+G SI + + ++
Sbjct: 553 ASQEYHIVKKSTRSLSTTQVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQM 612
Query: 1018 GIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERA 1058
GI+VK++ G+A DGRL GD++L V+G + GL+ + A
Sbjct: 613 GIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEA 653
Score = 48.9 bits (115), Expect = 4e-05
Identities = 26/67 (38%), Positives = 40/67 (59%)
Query: 996 LKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQ 1055
LK G+GLS+ K + + +K V KGGAA+ G + AGD++L+++G+ LVGL
Sbjct: 2754 LKTSAGLGLSLDGGKSSVTGDGPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVGLMH 2813
Query: 1056 ERAAELM 1062
A +M
Sbjct: 2814 FDAWNIM 2820
Score = 45.8 bits (107), Expect = 3e-04
Identities = 25/75 (33%), Positives = 38/75 (50%)
Query: 988 EPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDG 1047
E ++ + L ++ G GL A G + I V V GAA +G + GD LLSV+G
Sbjct: 2617 EEDVCFIVLNRKEGSGLGFSVAGGTDVEPKSITVHRVFSQGAASQEGTMNRGDFLLSVNG 2676
Query: 1048 RSLVGLSQERAAELM 1062
SL GL+ +++
Sbjct: 2677 ASLAGLAHGNVLKVL 2691
Score = 37.7 bits (86), Expect = 0.091
Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query: 984 PLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKL-GIYVKSVVKGGAADVDGRLAAGDQL 1042
P K+ ++ VTL K+ +GL I A A ++ GIY+ S+ G A ++ L+ GDQ+
Sbjct: 719 PGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQI 778
Query: 1043 LSVD 1046
L V+
Sbjct: 779 LEVN 782
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 65.9 bits (159), Expect = 3e-10
Identities = 37/90 (41%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 988 EPEIITVTLKK--QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
E EI V LKK + G+G I+ + G+ LGI++ SV GG AD+DG L GD+L+SV
Sbjct: 1088 EREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISV 1147
Query: 1046 DGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
+ SL G+S A E++ VTL +++
Sbjct: 1148 NSVSLEGVSHHAAIEILQNAPEDVTLVISQ 1177
Score = 57.8 bits (138), Expect = 8e-08
Identities = 37/95 (38%), Positives = 55/95 (57%), Gaps = 6/95 (6%)
Query: 987 KEPEIITVTL-KKQNGMGLSIVAA--KGAGQDKL---GIYVKSVVKGGAADVDGRLAAGD 1040
K +I V L K N +G+S+ KG + GIYVK+V+ GAA+ DGR+ GD
Sbjct: 1362 KPGDIFEVELAKNDNSLGISVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGD 1421
Query: 1041 QLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
++L+V+G SL G + ++A E + T VV L + K
Sbjct: 1422 RVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK 1456
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 12/107 (11%)
Query: 969 DYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGG 1028
D E+HL E+ EL E E++ +K + G L KG ++G YV V++
Sbjct: 1778 DLENHL--EDFEL------EVELLITLIKSEKG-SLGFTVTKG--NQRIGCYVHDVIQDP 1826
Query: 1029 AADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
A DGRL GD+L+ V+ + ++ A L+ S V L + +
Sbjct: 1827 AKS-DGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGR 1872
Score = 36.6 bits (83), Expect = 0.20
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 997 KKQNGMGLSIVAAKGAGQDKLG---IYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGL 1053
K +G+G S +++ + VK + G A G++ GD +L V+G SL GL
Sbjct: 1511 KNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGL 1570
Query: 1054 SQERAAELMTRTSSVVTL 1071
SQ+ + T+ V L
Sbjct: 1571 SQQEVISALRGTAPEVFL 1588
>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
isoform 3 [Homo sapiens]
Length = 2294
Score = 65.9 bits (159), Expect = 3e-10
Identities = 37/90 (41%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 988 EPEIITVTLKK--QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
E EI V LKK + G+G I+ + G+ LGI++ SV GG AD+DG L GD+L+SV
Sbjct: 897 EREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISV 956
Query: 1046 DGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
+ SL G+S A E++ VTL +++
Sbjct: 957 NSVSLEGVSHHAAIEILQNAPEDVTLVISQ 986
Score = 61.2 bits (147), Expect = 8e-09
Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
Query: 987 KEPEIITVTL-KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
K +I V L K N +G+S+ GIYVK+V+ GAA+ DGR+ GD++L+V
Sbjct: 1171 KPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAV 1230
Query: 1046 DGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
+G SL G + ++A E + T VV L + K
Sbjct: 1231 NGVSLEGATHKQAVETLRNTGQVVHLLLEK 1260
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 12/107 (11%)
Query: 969 DYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGG 1028
D E+HL E+ EL E E++ +K + G L KG ++G YV V++
Sbjct: 1582 DLENHL--EDFEL------EVELLITLIKSEKG-SLGFTVTKG--NQRIGCYVHDVIQDP 1630
Query: 1029 AADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
A DGRL GD+L+ V+ + ++ A L+ S V L + +
Sbjct: 1631 AKS-DGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGR 1676
Score = 36.6 bits (83), Expect = 0.20
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 997 KKQNGMGLSIVAAKGAGQDKLG---IYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGL 1053
K +G+G S +++ + VK + G A G++ GD +L V+G SL GL
Sbjct: 1315 KNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGL 1374
Query: 1054 SQERAAELMTRTSSVVTL 1071
SQ+ + T+ V L
Sbjct: 1375 SQQEVISALRGTAPEVFL 1392
>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
Length = 2485
Score = 65.9 bits (159), Expect = 3e-10
Identities = 37/90 (41%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 988 EPEIITVTLKK--QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
E EI V LKK + G+G I+ + G+ LGI++ SV GG AD+DG L GD+L+SV
Sbjct: 1088 EREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISV 1147
Query: 1046 DGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
+ SL G+S A E++ VTL +++
Sbjct: 1148 NSVSLEGVSHHAAIEILQNAPEDVTLVISQ 1177
Score = 61.2 bits (147), Expect = 8e-09
Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
Query: 987 KEPEIITVTL-KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
K +I V L K N +G+S+ GIYVK+V+ GAA+ DGR+ GD++L+V
Sbjct: 1362 KPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAV 1421
Query: 1046 DGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
+G SL G + ++A E + T VV L + K
Sbjct: 1422 NGVSLEGATHKQAVETLRNTGQVVHLLLEK 1451
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 12/107 (11%)
Query: 969 DYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGG 1028
D E+HL E+ EL E E++ +K + G L KG ++G YV V++
Sbjct: 1773 DLENHL--EDFEL------EVELLITLIKSEKG-SLGFTVTKG--NQRIGCYVHDVIQDP 1821
Query: 1029 AADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
A DGRL GD+L+ V+ + ++ A L+ S V L + +
Sbjct: 1822 AKS-DGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGR 1867
Score = 36.6 bits (83), Expect = 0.20
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 997 KKQNGMGLSIVAAKGAGQDKLG---IYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGL 1053
K +G+G S +++ + VK + G A G++ GD +L V+G SL GL
Sbjct: 1506 KNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGL 1565
Query: 1054 SQERAAELMTRTSSVVTL 1071
SQ+ + T+ V L
Sbjct: 1566 SQQEVISALRGTAPEVFL 1583
>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
2 [Homo sapiens]
Length = 2466
Score = 65.9 bits (159), Expect = 3e-10
Identities = 37/90 (41%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 988 EPEIITVTLKK--QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
E EI V LKK + G+G I+ + G+ LGI++ SV GG AD+DG L GD+L+SV
Sbjct: 1069 EREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISV 1128
Query: 1046 DGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
+ SL G+S A E++ VTL +++
Sbjct: 1129 NSVSLEGVSHHAAIEILQNAPEDVTLVISQ 1158
Score = 61.2 bits (147), Expect = 8e-09
Identities = 35/90 (38%), Positives = 52/90 (57%), Gaps = 1/90 (1%)
Query: 987 KEPEIITVTL-KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
K +I V L K N +G+S+ GIYVK+V+ GAA+ DGR+ GD++L+V
Sbjct: 1343 KPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAV 1402
Query: 1046 DGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
+G SL G + ++A E + T VV L + K
Sbjct: 1403 NGVSLEGATHKQAVETLRNTGQVVHLLLEK 1432
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 12/107 (11%)
Query: 969 DYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGG 1028
D E+HL E+ EL E E++ +K + G L KG ++G YV V++
Sbjct: 1754 DLENHL--EDFEL------EVELLITLIKSEKG-SLGFTVTKG--NQRIGCYVHDVIQDP 1802
Query: 1029 AADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAK 1075
A DGRL GD+L+ V+ + ++ A L+ S V L + +
Sbjct: 1803 AKS-DGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGR 1848
Score = 36.6 bits (83), Expect = 0.20
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 997 KKQNGMGLSIVAAKGAGQDKLG---IYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGL 1053
K +G+G S +++ + VK + G A G++ GD +L V+G SL GL
Sbjct: 1487 KNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGL 1546
Query: 1054 SQERAAELMTRTSSVVTL 1071
SQ+ + T+ V L
Sbjct: 1547 SQQEVISALRGTAPEVFL 1564
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 63.5 bits (153), Expect = 2e-09
Identities = 50/148 (33%), Positives = 67/148 (45%), Gaps = 15/148 (10%)
Query: 969 DYESHLLRENTELAQP---------LRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGI 1019
DY SH + +T QP L EP + V K G+G +IV G+D GI
Sbjct: 288 DYTSHS-QHSTATRQPSMTLQRAVSLEGEPRKV-VLHKGSTGLGFNIVG----GEDGEGI 341
Query: 1020 YVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAI 1079
+V ++ GG AD+ G L GDQ+LSV+G L G S E+AA + VT+ Q
Sbjct: 342 FVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPED 401
Query: 1080 YHGLATLLNQPSPMMQRISDRRGSGKPR 1107
Y ++ M S GSG R
Sbjct: 402 YARFEAKIHDLREQMMNHSMSSGSGSLR 429
Score = 63.2 bits (152), Expect = 2e-09
Identities = 45/122 (36%), Positives = 62/122 (50%), Gaps = 14/122 (11%)
Query: 986 RKEPEIITVT----LKKQNGMGLSIVAAKGAGQDKL----GIYVKSVVKGGAADVDGRLA 1037
R+ P + TV K G+G SI A G G + IYV ++ GGAA DGRL
Sbjct: 132 RRRPILETVVEIKLFKGPKGLGFSI--AGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQ 189
Query: 1038 AGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIY----HGLATLLNQPSPM 1093
GD+LL V+ SL ++ E A ++ TS VV L+V K IY +G + + SP
Sbjct: 190 VGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKVGKPTTIYMTDPYGPPDITHSYSPP 249
Query: 1094 MQ 1095
M+
Sbjct: 250 ME 251
Score = 47.4 bits (111), Expect = 1e-04
Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 988 EPEIITVTLKKQN-GMGLSIVAAKGAGQ--DKLGIYVKSVVKGGAADVDGRLAAGDQLLS 1044
E E +TL++ N G+G SI D GI++ ++ GGAA DGRL D +L
Sbjct: 42 EYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILR 101
Query: 1045 VDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAI 1079
V+ + +S +A E + S+V L V ++ I
Sbjct: 102 VNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPI 136
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 63.5 bits (153), Expect = 2e-09
Identities = 62/196 (31%), Positives = 87/196 (44%), Gaps = 31/196 (15%)
Query: 986 RKEPEIITVT----LKKQNGMGLSIVAAKGAGQDKL----GIYVKSVVKGGAADVDGRLA 1037
R+ P + TV K G+G SI A G G + IYV ++ GGAA DGRL
Sbjct: 288 RRRPILETVVEIKLFKGPKGLGFSI--AGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQ 345
Query: 1038 AGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIY----HGLATLLNQPSPM 1093
GD+LL V+ SL ++ E A ++ TS VV L+V K IY +G + + SP
Sbjct: 346 VGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKVGKPTTIYMTDPYGPPDITHSYSPP 405
Query: 1094 MQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLPWAEYSE-PKKLPGDDRLMKNRA 1152
M+ + SG NN T P + YS PK + DD +
Sbjct: 406 ME---NHLLSG------------NNGTLEYKTSLPPISPGRYSPIPKHMLVDDDYTRPPE 450
Query: 1153 DHRSSPN-VANQPPSP 1167
S+ N + ++P SP
Sbjct: 451 PVYSTVNKLCDKPASP 466
Score = 61.6 bits (148), Expect = 6e-09
Identities = 44/126 (34%), Positives = 59/126 (46%), Gaps = 5/126 (3%)
Query: 982 AQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQ 1041
A L EP + V K G+G +IV G+D GI+V ++ GG AD+ G L GDQ
Sbjct: 517 AVSLEGEPRKV-VLHKGSTGLGFNIVG----GEDGEGIFVSFILAGGPADLSGELQRGDQ 571
Query: 1042 LLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRR 1101
+LSV+G L G S E+AA + VT+ Q Y ++ M S
Sbjct: 572 ILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSS 631
Query: 1102 GSGKPR 1107
GSG R
Sbjct: 632 GSGSLR 637
Score = 47.4 bits (111), Expect = 1e-04
Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 988 EPEIITVTLKKQN-GMGLSIVAAKGAGQ--DKLGIYVKSVVKGGAADVDGRLAAGDQLLS 1044
E E +TL++ N G+G SI D GI++ ++ GGAA DGRL D +L
Sbjct: 198 EYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILR 257
Query: 1045 VDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAI 1079
V+ + +S +A E + S+V L V ++ I
Sbjct: 258 VNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPI 292
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 63.5 bits (153), Expect = 2e-09
Identities = 62/196 (31%), Positives = 87/196 (44%), Gaps = 31/196 (15%)
Query: 986 RKEPEIITVT----LKKQNGMGLSIVAAKGAGQDKL----GIYVKSVVKGGAADVDGRLA 1037
R+ P + TV K G+G SI A G G + IYV ++ GGAA DGRL
Sbjct: 183 RRRPILETVVEIKLFKGPKGLGFSI--AGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQ 240
Query: 1038 AGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIY----HGLATLLNQPSPM 1093
GD+LL V+ SL ++ E A ++ TS VV L+V K IY +G + + SP
Sbjct: 241 VGDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLKVGKPTTIYMTDPYGPPDITHSYSPP 300
Query: 1094 MQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLPWAEYSE-PKKLPGDDRLMKNRA 1152
M+ + SG NN T P + YS PK + DD +
Sbjct: 301 ME---NHLLSG------------NNGTLEYKTSLPPISPGRYSPIPKHMLVDDDYTRPPE 345
Query: 1153 DHRSSPN-VANQPPSP 1167
S+ N + ++P SP
Sbjct: 346 PVYSTVNKLCDKPASP 361
Score = 61.6 bits (148), Expect = 6e-09
Identities = 44/126 (34%), Positives = 59/126 (46%), Gaps = 5/126 (3%)
Query: 982 AQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQ 1041
A L EP + V K G+G +IV G+D GI+V ++ GG AD+ G L GDQ
Sbjct: 412 AVSLEGEPRKV-VLHKGSTGLGFNIVG----GEDGEGIFVSFILAGGPADLSGELQRGDQ 466
Query: 1042 LLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRR 1101
+LSV+G L G S E+AA + VT+ Q Y ++ M S
Sbjct: 467 ILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMMNHSMSS 526
Query: 1102 GSGKPR 1107
GSG R
Sbjct: 527 GSGSLR 532
Score = 47.4 bits (111), Expect = 1e-04
Identities = 31/95 (32%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 988 EPEIITVTLKKQN-GMGLSIVAAKGAGQ--DKLGIYVKSVVKGGAADVDGRLAAGDQLLS 1044
E E +TL++ N G+G SI D GI++ ++ GGAA DGRL D +L
Sbjct: 93 EYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILR 152
Query: 1045 VDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAI 1079
V+ + +S +A E + S+V L V ++ I
Sbjct: 153 VNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPI 187
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 63.2 bits (152), Expect = 2e-09
Identities = 112/494 (22%), Positives = 188/494 (38%), Gaps = 96/494 (19%)
Query: 1123 GSPESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKIT 1182
GSP S + +KLPG D ++ V + + G A +G A +
Sbjct: 186 GSPSSSD-------QDEKLPGQDESTAGTSEQNDILKVVEKRIACGPPQAKLNGQQAALA 238
Query: 1183 SVSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQD----RMAPPQNQWPNYEE 1238
S + PP + YP T FP S S+ R P W + E
Sbjct: 239 SQYRAMM------PPYMFQQYPRMTYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPE 292
Query: 1239 KPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWIN---QSSS 1295
+P + + S + + E E A ++ D + N +++S
Sbjct: 293 RPSILSASELKEL--DKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNS 350
Query: 1296 LDSSTSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPI----------- 1344
D + + E N+ +K T + TKS + IPA P P
Sbjct: 351 EDQGSKASE--NNENKKETDEVSNTKSS-------SQIPAQPSVAKVPYGKGPSFNQERG 401
Query: 1345 -RTDLPPPPP------PPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAE----- 1392
+ LPPPP PPP A +P P P PS Q A E
Sbjct: 402 TSSHLPPPPKLLAQQHPPPDRQA---------VPGRPGP------FPSKQQVADEDEIWK 446
Query: 1393 RRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK--PEK 1450
+R+R++ + E+AR E E +R E++RK A+++K EK
Sbjct: 447 QRRRQQSEISAAVERARKRREEEERRMEEQRKAA---------------CAEKLKRLDEK 491
Query: 1451 PSTLQR-PQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK-L 1508
L++ P IRE + +++ R+ + ++E D ++ KEK L
Sbjct: 492 LGILEKQPSPEEIREREREKE------REREKELEKEQEQEREKEREKDRERQQEKEKEL 545
Query: 1509 EKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEE 1568
EK+Q+ +M + QE + + +R E+ L+K M E + + L++ ++K E+ E
Sbjct: 546 EKEQEKQ-REMEKERKQEKEKELERQKEKEKELQK-MKEQEKECELEKEREKLEEKIEPR 603
Query: 1569 DDDVDTMLIMQRLE 1582
+ +++ M+ Q E
Sbjct: 604 EPNLEPMVEKQESE 617
Score = 39.7 bits (91), Expect = 0.024
Identities = 36/171 (21%), Positives = 80/171 (46%), Gaps = 13/171 (7%)
Query: 1392 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK-PEK 1450
ER K E R ++EK + E+ + K+RE E++ Q + + L Q+MK EK
Sbjct: 526 EREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEK 585
Query: 1451 PSTLQRPQETVIRELQPQQQ--PRTIERRDLQYITVSKEEL------SSGDSLSPDPWKR 1502
L++ +E + +++P++ +E+++ + +EE S+ P
Sbjct: 586 ECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVH 645
Query: 1503 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKR 1553
+ + + Q + ++ K+ Q +S P R + +++++ +WQ Q++
Sbjct: 646 ETEPESGSQPRPAVLSGYFKQFQ--KSLPPRFQRQQEQMKQ--QQWQQQQQ 692
Score = 33.1 bits (74), Expect = 2.2
Identities = 40/163 (24%), Positives = 63/163 (38%), Gaps = 43/163 (26%)
Query: 1336 TPVAVSQPIRT---DLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAE 1392
T V +P +T DLPPPPPPP PP P Q P Q
Sbjct: 1043 TEKVVVKPEKTEKKDLPPPPPPPQ----------------PPAPIQPQSVPPPIQ----- 1081
Query: 1393 RRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPA--------PFSPLTAQ 1444
E +++ E A L ++ ++ E+ L + T + PA +P+ +
Sbjct: 1082 ----PEAEKFPSTETATL---AQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKE 1134
Query: 1445 QMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKE 1487
+ +PEK + ++ VI +P +P + L T KE
Sbjct: 1135 EKQPEKVIS----KDLVIERPRPDSRPAVKKESTLPPRTYWKE 1173
Score = 31.6 bits (70), Expect = 6.5
Identities = 44/237 (18%), Positives = 83/237 (35%), Gaps = 38/237 (16%)
Query: 1099 DRRGSGKPRPKSEGFELYNNSTQNGSPESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSP 1158
D +GS P+ NNS GS S E +E KK + K+ + + P
Sbjct: 338 DEQGSNSPKE--------NNSEDQGSKAS------ENNENKKETDEVSNTKSSSQIPAQP 383
Query: 1159 NVANQPPSPGGKSAYASGTTAKITS----VSTGNLCTEEQTPPPRPEAYPIPTQTYTREY 1214
+VA P G GT++ + ++ + + Q P RP +P Q +
Sbjct: 384 SVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDE 443
Query: 1215 FTFPASKSQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTR------------SQEE 1262
+ Q ++ + E+ + + +++ R S EE
Sbjct: 444 IWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEE 503
Query: 1263 LRE-------DKAYQLERHR-IEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSK 1311
+RE ++ +LE+ + E +R+ D + + L+ Q + K
Sbjct: 504 IREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERK 560
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 62.0 bits (149), Expect = 4e-09
Identities = 45/127 (35%), Positives = 68/127 (53%), Gaps = 10/127 (7%)
Query: 368 RADGSGYGSTLPPEKLPYLVELSPDGSDSRDKPKLYRLQLSVTEVGTEKLDDNS-IQLFG 426
R DG G P+K P+LV L+ D S + LY ++ +T VG E + I L G
Sbjct: 477 REDGGTLG-VFSPKKTPHLVNLNEDPLMS--ECLLYYIKDGITRVGREDGERRQDIVLSG 533
Query: 427 PGIQPHHCDLTN-----MDGVVTVTPRSMDAETYVEGQRISETTMLQSGMKVQFGASHVF 481
I+ HC + + VVT+ P A+TYV G++++E ++L+SG ++ G SHVF
Sbjct: 534 HFIKEEHCVFRSDSRGGSEAVVTLEPCE-GADTYVNGKKVTEPSILRSGNRIIMGKSHVF 592
Query: 482 KFVDPSQ 488
+F P Q
Sbjct: 593 RFNHPEQ 599
>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
Length = 1332
Score = 61.6 bits (148), Expect = 6e-09
Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 10/106 (9%)
Query: 994 VTLKKQ-NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVG 1052
V +K Q G+G SIV K + +GIYVK++ GGAA DGRL GD++L ++G S+ G
Sbjct: 218 VLMKGQAKGLGFSIVGGKDSIYGPIGIYVKTIFAGGAAAADGRLQEGDEILELNGESMAG 277
Query: 1053 LSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRIS 1098
L+ + A + + AK+G + + T L P + +S
Sbjct: 278 LTHQDALQ---------KFKQAKKGLLTLTVRTRLTAPPSLCSHLS 314
Score = 43.1 bits (100), Expect = 0.002
Identities = 29/90 (32%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Query: 974 LLRENTELAQPLRKEPEIITVT-LKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADV 1032
L+ E L + K+ + I VT L K+ G GL A GA + I V V G A
Sbjct: 1093 LIEEVKVLDEATLKQLDGIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQ 1152
Query: 1033 DGRLAAGDQLLSVDGRSLVGLSQERAAELM 1062
+G + G+++LS++G+SL G + A ++
Sbjct: 1153 EGTIQKGNEVLSINGKSLKGTTHHDALAIL 1182
Score = 40.4 bits (93), Expect = 0.014
Identities = 21/72 (29%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Query: 988 EPEIITVTLKKQN-GMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVD 1046
E + TVTL+K + G+G S+ KG+ + + + KG A++ + GD++L +
Sbjct: 1229 EATVCTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLG 1288
Query: 1047 GRSLVGLSQERA 1058
G ++ GL++ A
Sbjct: 1289 GTAMQGLTRFEA 1300
Score = 36.2 bits (82), Expect = 0.26
Identities = 19/56 (33%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Query: 991 IITVTLKKQNGMGLSI-VAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
++ V+L+K+ G+GL I + + Q GI+V ++ G A +DGRL GD+++ +
Sbjct: 353 MVEVSLQKEAGVGLGIGLCSVPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEI 408
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 61.6 bits (148), Expect = 6e-09
Identities = 43/129 (33%), Positives = 64/129 (49%), Gaps = 8/129 (6%)
Query: 368 RADGSGYGSTLPPEKLPYLVELSPDGSDSRDKPKLYRLQLSVTEVGTEKLDDNS-IQLFG 426
R DG G P+K P+LV L+ D S + LY ++ +T VG + I L G
Sbjct: 471 REDGGTLG-VFSPKKTPHLVNLNEDPLMS--ECLLYYIKDGITRVGQADAERRQDIVLSG 527
Query: 427 PGIQPHHC----DLTNMDGVVTVTPRSMDAETYVEGQRISETTMLQSGMKVQFGASHVFK 482
I+ HC + +N V+ +ETYV G+R+S+ L+SG ++ G +HVF+
Sbjct: 528 AHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFR 587
Query: 483 FVDPSQDHA 491
F P Q A
Sbjct: 588 FNHPEQARA 596
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 61.6 bits (148), Expect = 6e-09
Identities = 43/129 (33%), Positives = 64/129 (49%), Gaps = 8/129 (6%)
Query: 368 RADGSGYGSTLPPEKLPYLVELSPDGSDSRDKPKLYRLQLSVTEVGTEKLDDNS-IQLFG 426
R DG G P+K P+LV L+ D S + LY ++ +T VG + I L G
Sbjct: 471 REDGGTLG-VFSPKKTPHLVNLNEDPLMS--ECLLYYIKDGITRVGQADAERRQDIVLSG 527
Query: 427 PGIQPHHC----DLTNMDGVVTVTPRSMDAETYVEGQRISETTMLQSGMKVQFGASHVFK 482
I+ HC + +N V+ +ETYV G+R+S+ L+SG ++ G +HVF+
Sbjct: 528 AHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFR 587
Query: 483 FVDPSQDHA 491
F P Q A
Sbjct: 588 FNHPEQARA 596
>gi|119943106 synapse-associated protein 102 isoform a [Homo sapiens]
Length = 817
Score = 61.2 bits (147), Expect = 8e-09
Identities = 38/103 (36%), Positives = 58/103 (56%), Gaps = 10/103 (9%)
Query: 986 RKEPEIITVT----LKKQNGMGLSIVAAKGAGQDKL----GIYVKSVVKGGAADVDGRLA 1037
R++P T+ LK G+G SI A G G + IY+ +++GGAA DGRL
Sbjct: 216 RRQPPPETIMEVNLLKGPKGLGFSI--AGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQ 273
Query: 1038 AGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIY 1080
GD+LL+V+ +L + E A + TS +V L+VAK G+++
Sbjct: 274 IGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKVAKPGSLH 316
Score = 60.1 bits (144), Expect = 2e-08
Identities = 46/144 (31%), Positives = 69/144 (47%), Gaps = 11/144 (7%)
Query: 973 HLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADV 1032
H+L E + +EP I + K G+G +IV G+D GI+V ++ GG AD+
Sbjct: 373 HMLAE-----EDFTREPRKI-ILHKGSTGLGFNIVG----GEDGEGIFVSFILAGGPADL 422
Query: 1033 DGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSP 1092
G L GD++LSV+G +L + E+AA + R VT+ + Y + ++
Sbjct: 423 SGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHDLRE 482
Query: 1093 MMQRISDRRGSGKPRPKSEGFELY 1116
M S GSG R SE LY
Sbjct: 483 QMMNSSMSSGSGSLR-TSEKRSLY 505
Score = 41.6 bits (96), Expect = 0.006
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
Query: 994 VTLKKQN-GMGLSIVAAKGAGQ--DKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSL 1050
+ L++ N G+G SI D GI++ ++ GGAA +DGRL D +L V+ +
Sbjct: 132 IVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDV 191
Query: 1051 VGLSQERAAELMTRTSSVVTLEVAKQ 1076
+ RA E + VV L V ++
Sbjct: 192 SEVVHSRAVEALKEAGPVVRLVVRRR 217
>gi|63999048 syntaxin binding protein 4 [Homo sapiens]
Length = 553
Score = 60.1 bits (144), Expect = 2e-08
Identities = 28/79 (35%), Positives = 48/79 (60%), Gaps = 1/79 (1%)
Query: 985 LRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLS 1044
L K+P +T+ K+ G+GL ++ + L +Y++ ++ GG DGRL GDQL+S
Sbjct: 14 LEKDPAFQMITIAKETGLGLKVLGGINRNEGPL-VYIQEIIPGGDCYKDGRLKPGDQLVS 72
Query: 1045 VDGRSLVGLSQERAAELMT 1063
V+ S++G+S E A ++T
Sbjct: 73 VNKESMIGVSFEEAKSIIT 91
>gi|119943108 synapse-associated protein 102 isoform b [Homo sapiens]
Length = 512
Score = 59.7 bits (143), Expect = 2e-08
Identities = 48/149 (32%), Positives = 70/149 (46%), Gaps = 14/149 (9%)
Query: 976 RENTELAQPLR--------KEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKG 1027
R + A PLR +EP I + K G+G +IV G+D GI+V ++ G
Sbjct: 26 RASQRWAWPLRSLRPGGDAREPRKI-ILHKGSTGLGFNIVG----GEDGEGIFVSFILAG 80
Query: 1028 GAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLL 1087
G AD+ G L GD++LSV+G +L + E+AA + R VT+ + Y + +
Sbjct: 81 GPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKI 140
Query: 1088 NQPSPMMQRISDRRGSGKPRPKSEGFELY 1116
+ M S GSG R SE LY
Sbjct: 141 HDLREQMMNSSMSSGSGSLR-TSEKRSLY 168
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 59.7 bits (143), Expect = 2e-08
Identities = 40/105 (38%), Positives = 56/105 (53%), Gaps = 4/105 (3%)
Query: 383 LPYLVELSPDGSDSRDKPKLYRLQLSVTEVGTEKLDDN-SIQLFGPGIQPHHCDLTNMDG 441
LP LV L+ D S + LY ++ T VG K + + IQL G I HC + N G
Sbjct: 800 LPNLVNLNEDPQLS--EMLLYMIKEGTTTVGKYKPNSSHDIQLSGVLIADDHCTIKNFGG 857
Query: 442 VVTVTPRSMDAETYVEGQRISETTMLQSGMKVQFGASHVFKFVDP 486
V++ P +A+TYV G+ I E T+L+ G +V G H F+F P
Sbjct: 858 TVSIIPVG-EAKTYVNGKHILEITVLRHGDRVILGGDHYFRFNHP 901
>gi|148612825 Rap GTPase interactor [Homo sapiens]
Length = 1075
Score = 58.9 bits (141), Expect = 4e-08
Identities = 86/398 (21%), Positives = 153/398 (38%), Gaps = 69/398 (17%)
Query: 589 IEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPD------ISPTE 642
+EF ED+ L I+ KL+P ++L + ++ ++ ++P +
Sbjct: 407 LEFEPHLEDTLLQRIMTLIEPGGDDHKLTPAFLLCLCIQHSATH-FQPGTFGQLLLKIAR 465
Query: 643 RTHKVIAVVNKMVSMMEGVIQKQKNIAGA-----------LAFWMANASELLNFIKQD-- 689
+ + K ++ + +Q+ ++A + FWM+N+ ELL FI+Q
Sbjct: 466 LIRETVWEKTKELAEKQAQLQEPISLASCAMADLVPDLQPILFWMSNSIELLYFIQQKCP 525
Query: 690 ----------------RDLSRITLDAQD----VLAHLVQMAFKYLVHCLQSELNNYMPAF 729
L TL A + VL +V AF+ V+ + L +PA
Sbjct: 526 LYMQSMEEQLDITGSKESLFSCTLTASEEAMAVLEEVVLYAFQQCVYYVSKSLYICLPAL 585
Query: 730 LDDPEENSLQR------PKIDDVLHTLTG----AMSLLRRCRVNAALTIQLFSQLFHFIN 779
L+ P + +R P++ + L + A+ LLR+ +V+ + Q+ + LF F
Sbjct: 586 LECPPFQTERRESWSSAPELPEELRRVVSVYQAALDLLRQLQVHPEVASQMLAYLFFFSG 645
Query: 780 MWLFNRLVTDPDSGLCSHY-WGAIIRQQLGHIEAWAEKQGLELAADCHLSRIVQATTLLT 838
L N+L+ S C H+ G +L + W G A + ++ LL
Sbjct: 646 TLLLNQLLDRGPSLSCFHWPRGVQACARLQQLLEWMRSAGFGAAGEHFFQKLSCTLNLLA 705
Query: 839 MDKYAPDDIPNINSTCFK-----LNSLQLQALLQNYHCAPDEPFIPTDLIENVVTVAENT 893
+ + ++ T + L+ QL LL +Y A P E
Sbjct: 706 TPR---AQLIQMSWTALRAAFPALSPAQLHRLLTHYQLA--SAMGPMSTWE----PGAQD 756
Query: 894 ADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRN 931
+ E RS+ E P P +LP DG+ D+ N
Sbjct: 757 SPEAFRSEDVLESYENPP----PIVLPSDGFQVDLEAN 790
Score = 53.5 bits (127), Expect = 2e-06
Identities = 28/86 (32%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Query: 991 IITVTLKK-QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRS 1049
+ TV L++ +G+G+ ++ G+Y+++++ G A DGRL+ GD++L V+G S
Sbjct: 974 VFTVELERGPSGLGMGLIDGMHTHLGAPGLYIQTLLPGSPAAADGRLSLGDRILEVNGSS 1033
Query: 1050 LVGLSQERAAELMTRTSSVVTLEVAK 1075
L+GL RA +L+ + VAK
Sbjct: 1034 LLGLGYLRAVDLIRHGGKKMRFLVAK 1059
Score = 44.3 bits (103), Expect = 0.001
Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Query: 247 GTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVMLPPGAQ 306
G L+++ DS+ YK++L + T A V EALE+Y L+ Y + V+ G
Sbjct: 63 GVLKVFGDSVCTGTHYKSVLATGTSSARELVKEALERYALDPRQAGQYVLCDVVGQAGDA 122
Query: 307 HSDEKGAKEIILDDDECPLQIFREWPSDKGI-LVFQLKRR 345
+ + D E PL I W +G+ F+L++R
Sbjct: 123 GQRWQARCFRVFGDSEKPLLIQELWKPREGLSRRFELRKR 162
>gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens]
Length = 1356
Score = 58.9 bits (141), Expect = 4e-08
Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 3/93 (3%)
Query: 992 ITVTLKK-QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSL 1050
+ + LKK G+G SI + IYVK+++ GAA DGRL AGD+L+ V+G L
Sbjct: 460 LNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDL 519
Query: 1051 VGLSQERAAELM--TRTSSVVTLEVAKQGAIYH 1081
VG SQE L+ T+ V+L V +Q +H
Sbjct: 520 VGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFH 552
Score = 58.9 bits (141), Expect = 4e-08
Identities = 46/132 (34%), Positives = 64/132 (48%), Gaps = 30/132 (22%)
Query: 1001 GMGLSIVAAKGA-GQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAA 1059
G+G+S+ + LGI+VKS++ GGAA DGRL DQL++V+G SL+G + + A
Sbjct: 600 GLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAM 659
Query: 1060 ELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNS 1119
E + R+ S E K+G M+Q I RR S KS
Sbjct: 660 ETLRRSMST---EGNKRG---------------MIQLIVARRISKCNELKSP-------- 693
Query: 1120 TQNGSPESPQLP 1131
GSP P+LP
Sbjct: 694 ---GSPPGPELP 702
>gi|119120907 par-3 partitioning defective 3 homolog B isoform a [Homo
sapiens]
Length = 1104
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/109 (34%), Positives = 59/109 (54%), Gaps = 17/109 (15%)
Query: 976 RENTELAQPLRKEPEIITVTLKKQN--------------GMGLSIVAAKG--AGQDKLGI 1019
+E L + L+ EP+ ++L+ G+G+S+ K G D LGI
Sbjct: 469 QEGHFLPRELKGEPDCCALSLETSEQLTFEIPLNDSGSAGLGVSLKGNKSRETGTD-LGI 527
Query: 1020 YVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSV 1068
++KS++ GGAA DGRL DQL++V+G SL+G S A E + R+ S+
Sbjct: 528 FIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSM 576
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/93 (33%), Positives = 53/93 (56%), Gaps = 3/93 (3%)
Query: 987 KEPEIITVTLKK-QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
K + I + LKK G+G ++V + I+VK+++ GAA DGRL +GD++L V
Sbjct: 377 KNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAIKDGRLQSGDRILEV 436
Query: 1046 DGRSLVGLSQERAAELM--TRTSSVVTLEVAKQ 1076
+GR + G +QE ++ T+ +L +A+Q
Sbjct: 437 NGRDVTGRTQEELVAMLRSTKQGETASLVIARQ 469
>gi|119120903 par-3 partitioning defective 3 homolog B isoform c [Homo
sapiens]
Length = 1136
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/109 (34%), Positives = 59/109 (54%), Gaps = 17/109 (15%)
Query: 976 RENTELAQPLRKEPEIITVTLKKQN--------------GMGLSIVAAKG--AGQDKLGI 1019
+E L + L+ EP+ ++L+ G+G+S+ K G D LGI
Sbjct: 469 QEGHFLPRELKGEPDCCALSLETSEQLTFEIPLNDSGSAGLGVSLKGNKSRETGTD-LGI 527
Query: 1020 YVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSV 1068
++KS++ GGAA DGRL DQL++V+G SL+G S A E + R+ S+
Sbjct: 528 FIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSM 576
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/93 (33%), Positives = 53/93 (56%), Gaps = 3/93 (3%)
Query: 987 KEPEIITVTLKK-QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1045
K + I + LKK G+G ++V + I+VK+++ GAA DGRL +GD++L V
Sbjct: 377 KNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAIKDGRLQSGDRILEV 436
Query: 1046 DGRSLVGLSQERAAELM--TRTSSVVTLEVAKQ 1076
+GR + G +QE ++ T+ +L +A+Q
Sbjct: 437 NGRDVTGRTQEELVAMLRSTKQGETASLVIARQ 469
>gi|45827729 scribble isoform b [Homo sapiens]
Length = 1630
Score = 58.5 bits (140), Expect = 5e-08
Identities = 128/558 (22%), Positives = 207/558 (37%), Gaps = 109/558 (19%)
Query: 972 SHLLRENTELAQPLRKEPE---IITVTLKKQNG--MGLSIVA-AKG-AGQDK----LGIY 1020
S LLR EL+ +R++P + + ++K G +G+SI A+G AG + GI+
Sbjct: 1076 SALLRPCLELSLLVRRDPAPPGLRELCIQKAPGERLGISIRGGARGHAGNPRDPTDEGIF 1135
Query: 1021 VKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTL------EVA 1074
+ V GAA DGRL G +LL V+ +SL+GL+ A +L+ +T+ E +
Sbjct: 1136 ISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLVCDGFEAS 1195
Query: 1075 KQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQLPWAE 1134
A+ + N P I R E ++ + SPE P
Sbjct: 1196 TDAALEVSPGVIAN---PFAAGIGHR----------NSLESISSIDRELSPEGP------ 1236
Query: 1135 YSEPKKLPGDD-------------RLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKI 1181
+ K+LPG L + D+R+ V PS G SG
Sbjct: 1237 -GKEKELPGQTLHWGPEATEAAGRGLQPLKLDYRALAAV----PSAGSVQRVPSGAAGGK 1291
Query: 1182 TSVSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPH 1241
+ S + ++ PP P+ P + R + P S + AP Q P P
Sbjct: 1292 MAESPCSPSGQQPPSPPSPDELPANVKQAYRAFAAVPTSHPPED-APAQPPTPGPAASPE 1350
Query: 1242 MHTDSNHSSIAIQRVTRSQEE----------------LREDKAYQLERHRIEAAMDRKSD 1285
+ V Q E ++E++A +L++ R A M R++
Sbjct: 1351 QLSFRERQKYFELEVRVPQAEGPPKRVSLVGADDLRKMQEEEARKLQQKR--AQMLREA- 1407
Query: 1286 SDMWINQSSSLDSSTSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIR 1345
++ +LD T +E S P ++PA+ P P+ P+R
Sbjct: 1408 AEAGAEARLALDGETLGEEEQEDEQPPWASPS------PTSRQSPASPP--PLGGGAPVR 1459
Query: 1346 TDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEK 1405
T + + + P PP P + L A++ A E KR W
Sbjct: 1460 TAKAE---------RRHQERLRVQSPEPPAP---ERALSPAELRALEAEKR---ALWRAA 1504
Query: 1406 EKARLEEERERKR----REQE----RKLGQMRTQSLNPAPF-SPLTAQQMKPE---KPST 1453
LE++ R + R QE R + ++ +PAP SP + + P+ P
Sbjct: 1505 RMKSLEQDALRAQMVLSRSQEGRGTRGPLERLAEAPSPAPTPSPTPVEDLGPQTSTSPGR 1564
Query: 1454 LQRPQETVIRELQPQQQP 1471
L +R L+P P
Sbjct: 1565 LSPDFAEELRSLEPSPSP 1582
Score = 50.8 bits (120), Expect = 1e-05
Identities = 42/137 (30%), Positives = 66/137 (48%), Gaps = 8/137 (5%)
Query: 978 NTELAQPLRKEPEIITVTLKKQNG-MGLSIVAAKGA----GQDKLGIYVKSVVKGGAADV 1032
N L +P R E E +T+T+ +Q G +G+SI KG+ G D+ GI++ V + G A
Sbjct: 713 NNLLIEPARIEEEELTLTILRQTGGLGISIAGGKGSTPYKGDDE-GIFISRVSEEGPAAR 771
Query: 1033 DGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSP 1092
G + GD+LL V+G +L G A E + + V + V ++ + A + P
Sbjct: 772 AG-VRVGDKLLEVNGVALQGAEHHEAVEALRGAGTAVQMRVWRERMVEPENAVTITPLRP 830
Query: 1093 MMQ-RISDRRGSGKPRP 1108
+RRG G P
Sbjct: 831 EDDYSPRERRGGGLRLP 847
Score = 49.3 bits (116), Expect = 3e-05
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 5/96 (5%)
Query: 984 PLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLG---IYVKSVVKGGAADVDGRLAAGD 1040
PLR+ + + + G+G SI KG+ + G I+V + +GGAA G L GD
Sbjct: 856 PLRQRH--VACLARSERGLGFSIAGGKGSTPYRAGDAGIFVSRIAEGGAAHRAGTLQVGD 913
Query: 1041 QLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQ 1076
++LS++G + + A L+T S + L + ++
Sbjct: 914 RVLSINGVDVTEARHDHAVSLLTAASPTIALLLERE 949
Score = 35.0 bits (79), Expect = 0.59
Identities = 40/144 (27%), Positives = 64/144 (44%), Gaps = 14/144 (9%)
Query: 981 LAQPLRKEPEIITVTLKKQNG-MGLSIVAAKGA-----GQDKLGIYVKSVVKGGAADVDG 1034
LA L + + L + G +GLSIV G + G+++ V+ G A G
Sbjct: 992 LAAALEGPYPVEEIRLPRAGGPLGLSIVGGSDHSSHPFGVQEPGVFISKVLPRGLAARSG 1051
Query: 1035 RLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSP-- 1092
L GD++L+V+G+ + + + A + R ++L V + A GL L Q +P
Sbjct: 1052 -LRVGDRILAVNGQDVRDATHQEAVSALLRPCLELSLLVRRDPA-PPGLRELCIQKAPGE 1109
Query: 1093 ---MMQRISDRRGSGKPR-PKSEG 1112
+ R R +G PR P EG
Sbjct: 1110 RLGISIRGGARGHAGNPRDPTDEG 1133
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,950,378
Number of Sequences: 37866
Number of extensions: 3676104
Number of successful extensions: 35578
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 321
Number of HSP's successfully gapped in prelim test: 1039
Number of HSP's that attempted gapping in prelim test: 21819
Number of HSP's gapped (non-prelim): 9345
length of query: 1612
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1496
effective length of database: 13,855,062
effective search space: 20727172752
effective search space used: 20727172752
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.