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Search of human proteins with 89886470
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89886470 hypothetical protein LOC84960 [Homo sapiens]
(534 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89886470 hypothetical protein LOC84960 [Homo sapiens] 1035 0.0
gi|117553613 coiled-coil domain containing 151 [Homo sapiens] 120 3e-27
gi|7705415 hook homolog 1 [Homo sapiens] 57 6e-08
gi|50083279 centrosome protein 4 [Homo sapiens] 56 7e-08
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 55 1e-07
gi|71061468 centromere protein E [Homo sapiens] 55 2e-07
gi|38044112 restin isoform b [Homo sapiens] 55 2e-07
gi|4506751 restin isoform a [Homo sapiens] 55 2e-07
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 54 5e-07
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 54 5e-07
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 54 5e-07
gi|21735548 centrosomal protein 2 [Homo sapiens] 53 8e-07
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 52 1e-06
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 52 2e-06
gi|187761324 shootin1 isoform a [Homo sapiens] 51 2e-06
gi|50511340 shootin1 isoform b [Homo sapiens] 51 2e-06
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 51 3e-06
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 50 4e-06
gi|31982906 cingulin-like 1 [Homo sapiens] 50 7e-06
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 49 9e-06
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 49 9e-06
gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isof... 49 1e-05
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 49 2e-05
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 48 2e-05
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 48 2e-05
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 48 2e-05
gi|4758648 kinesin family member 5B [Homo sapiens] 48 3e-05
gi|118498362 kinectin 1 isoform b [Homo sapiens] 47 3e-05
gi|118498356 kinectin 1 isoform a [Homo sapiens] 47 3e-05
gi|118498368 kinectin 1 isoform c [Homo sapiens] 47 3e-05
>gi|89886470 hypothetical protein LOC84960 [Homo sapiens]
Length = 534
Score = 1035 bits (2676), Expect = 0.0
Identities = 534/534 (100%), Positives = 534/534 (100%)
Query: 1 MRRHSETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWA 60
MRRHSETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWA
Sbjct: 1 MRRHSETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWA 60
Query: 61 LAKKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQK 120
LAKKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQK
Sbjct: 61 LAKKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQK 120
Query: 121 LESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLK 180
LESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLK
Sbjct: 121 LESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLK 180
Query: 181 TVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARE 240
TVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARE
Sbjct: 181 TVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARE 240
Query: 241 NRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSGVT 300
NRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSGVT
Sbjct: 241 NRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSGVT 300
Query: 301 AVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLELEEAVL 360
AVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLELEEAVL
Sbjct: 301 AVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLELEEAVL 360
Query: 361 KFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQMGIDNLYVRLMGI 420
KFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQMGIDNLYVRLMGI
Sbjct: 361 KFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQMGIDNLYVRLMGI 420
Query: 421 TLPATQREVVLSNTLDLNSKLAYCEGKLTYLADRVQMVSRTEEGDTKVRDTLESSTLMEK 480
TLPATQREVVLSNTLDLNSKLAYCEGKLTYLADRVQMVSRTEEGDTKVRDTLESSTLMEK
Sbjct: 421 TLPATQREVVLSNTLDLNSKLAYCEGKLTYLADRVQMVSRTEEGDTKVRDTLESSTLMEK 480
Query: 481 YNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIEGKLKAAKKKKK 534
YNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIEGKLKAAKKKKK
Sbjct: 481 YNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIEGKLKAAKKKKK 534
>gi|117553613 coiled-coil domain containing 151 [Homo sapiens]
Length = 595
Score = 120 bits (301), Expect = 3e-27
Identities = 129/545 (23%), Positives = 242/545 (44%), Gaps = 23/545 (4%)
Query: 2 RRHSETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWAL 61
R + V Q EL QL E R + + N+ +N+ T++ LR +
Sbjct: 60 RGAGKPSVHSQVAELHKKIQLLEGDRKAFFESSQWNIKKNQETISQLRKETKALELKLLD 119
Query: 62 AKKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKL 121
K D+ + +A + + ++ E L + ++V N L H V R ++L
Sbjct: 120 LLKGDEKVV-QAVIREWKWEKPYLKNRTGQALEHLDHRLREKVKQQNALRHQVVLRQRRL 178
Query: 122 ESMQLELDSLR--SQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYL 179
E +QL+ SLR +A + + +R LEN +EK +K +++I +YL L YL
Sbjct: 179 EELQLQ-HSLRLLEMAEAQNRHTEVAKTMRNLENRLEKAQMKAQEAEHITSVYLQLKAYL 237
Query: 180 KTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRAR 239
LD ++ VV EL + +++Q+A+ D K ++ E + + ER+ R
Sbjct: 238 MDESLNLENRLDSMEAEVVRTKHELEALHVVNQEALNARDIAKNQLQYLEETLVRERKKR 297
Query: 240 ENRLNQQKKLID--KIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQS 297
E +++ KK + K+ + K R + L + ++L + +E YQ
Sbjct: 298 ERYISECKKRAEEKKLENERMERKTHREHLLLQSDDTIQ--DSLHAKEEELRQRWSMYQM 355
Query: 298 GVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLELEE 357
V + KVK A + RFLAQ +T LE + E+ V+LK +QL+ E
Sbjct: 356 EV--IFGKVKDATGTDETHSLVRRFLAQGDTFAQLETLKSENEQTLVRLKQEKQQLQREL 413
Query: 358 AVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQMGIDNLYVRL 417
LK+ + + +S + ++ + + LK+EE R A + + + + +++L +L
Sbjct: 414 EDLKYSGEATLVSQQKLQAEAQERLKKEERRHAEAKDQLERALRAMQVAKDSLEHLASKL 473
Query: 418 MGITLPATQ---REVVLSNTLDLNSKLAYCEGKLTYLADRVQMVSRTEE----GDTKVRD 470
+ IT+ + +E+ + + L E KL L ++Q E + +
Sbjct: 474 IHITVEDGRFAGKELDPQADNYVPNLLGLVEEKLLKLQAQLQGHDVQEMLCHIANREFLA 533
Query: 471 TLESSTLMEKYNTRIS--FENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIEGKLKA 528
+LE + +YNTRI+ ++ D + + + + V +RA +K ++Q+LIE K
Sbjct: 534 SLEGR--LPEYNTRIALPLATSKDKFFD--EESEEEDNEVVTRASLKIRSQKLIESHKKH 589
Query: 529 AKKKK 533
+ ++
Sbjct: 590 RRSRR 594
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 56.6 bits (135), Expect = 6e-08
Identities = 80/412 (19%), Positives = 169/412 (41%), Gaps = 25/412 (6%)
Query: 9 VEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWA-------L 61
+EE + L +L+++C L +Q ++N N + D + +
Sbjct: 184 LEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDDPNTVV 243
Query: 62 AKKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKL 121
AKKY + + RL + V E+L K + + + ++ L L ++
Sbjct: 244 AKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLA----EET 299
Query: 122 ESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKT 181
+++ E+D LR+ D + + ++I RQ ++ ++ T Q +++Y+ L+
Sbjct: 300 RALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVSLEE 359
Query: 182 VLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRAREN 241
L + + + + Y ++ D+ + D + M++ +EE+ E
Sbjct: 360 ELK----KANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKR-----LEEKH--EA 408
Query: 242 RLNQQKKLIDKIHT-KETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSGVT 300
L ++++LI++ T KET+E+ R Q+ D + ++ T +EY+ V
Sbjct: 409 LLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYRE-VF 467
Query: 301 AVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLELE-EAV 359
++ +R R + E +M + E + K +++L+ + E +
Sbjct: 468 IRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDL 527
Query: 360 LKFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQMGID 411
K Q+ S S K+ L+ E+L H + K QEL+ +Q I+
Sbjct: 528 QKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDIN 579
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 56.2 bits (134), Expect = 7e-08
Identities = 87/443 (19%), Positives = 185/443 (41%), Gaps = 61/443 (13%)
Query: 87 STMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLESMQLELDSLRSQPDASKEELRLLQ 146
+++ +V E+L++ V D H L I +RG+ LES Q ++ L + D EL L
Sbjct: 667 NSLRIVNEQLQRSVDDY--QHRLSI----KRGE-LESAQAQIKILEEKID----ELNLKM 715
Query: 147 IIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSD 206
+ E ++ K I +I + D+L+ + ++ LQ + N ++
Sbjct: 716 TSQDEEAHVMKKTIGVIDKEK---------DFLQETVDEKTEKIANLQENLANKEKAVAQ 766
Query: 207 MKIMSQDAMMITDEVKRNM--RQREASFIEER------------RARENRLNQQKKLIDK 252
MKIM + +++K + R RE + + + R+RE + ++L D
Sbjct: 767 MKIMISECESSVNQLKETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKENRRLQDD 826
Query: 253 IHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSGVTA-------VVEK 305
+ T + ++ L+ + + E +K R + T ++S + A ++++
Sbjct: 827 LATMARENQ----EISLELEAAVQEKEEMKSRVHKYITEVSRWESLMAAKEKENQDLLDR 882
Query: 306 VKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLELEEAVLKFRQK 365
+ + W++ + ++ LEL D E R ++ + + + E++E +
Sbjct: 883 FQMLHNRAEDWEVKAHQAEGESSSVRLELLSIDTERRHLRERVELLEKEIQEHINAHHAY 942
Query: 366 PSSI-SFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQMGIDNLYVRLMGITLPA 424
S I S ++ + L+ +E+ ++++ +EL + + G D + +L L
Sbjct: 943 ESQISSMAKAMSRLEEELRHQEDEKATVLNDLSSLRELCIKLDSGKDIMTQQLNSKNLEF 1002
Query: 425 TQREVVLSNT---LDLNSKLAYCEGKLTYLADRVQMVSR---------TEEGDTKVRDTL 472
+ V L N DL K E + + +R + E DT+++
Sbjct: 1003 ERVVVELENVKSESDLLKKQLSNERHTVKNLESLLATNRDKEFHSHLTSHEKDTEIQLLK 1062
Query: 473 ESSTLMEKYNTRISFENREEDMI 495
E TL E ++++ ++RE M+
Sbjct: 1063 EKLTLSE---SKLTSQSRENTML 1082
Score = 36.6 bits (83), Expect = 0.059
Identities = 107/568 (18%), Positives = 233/568 (41%), Gaps = 81/568 (14%)
Query: 1 MRRHSETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWA 60
+ RH E +E +EL + + + + ++Q ++E M + + L L + R + +
Sbjct: 329 LERHKEEVLETADKELGEAKK-EIKRKLSEMQDLEETMAKLQLELNLCQKEKERLSDE-- 385
Query: 61 LAKKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQK 120
L K D T+ + RL+ + V +L V +R+ + H ++RR +
Sbjct: 386 LLVKSDLETVVHQLEQEKQ-RLSKKVESFAVTERQLTLEV-ERMRLE----HGIKRRDRS 439
Query: 121 LESMQLELDSLRSQPDASKEELRLLQIIRQL-----------ENNIEKTMIKIITSQNIH 169
+ L + + D K+EL LQ I Q +++I +T K + IH
Sbjct: 440 PSRLDTFLKGIEEERDYYKKELERLQHIIQRRSCSTSYSAREKSSIFRTPEKGDYNSEIH 499
Query: 170 LLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQRE 229
+ + D L+ +L + ++ +Q+ V +E + ++ +A +++ Q
Sbjct: 500 QITRE-RDELQRMLERFEKYMEDIQSNVKLLTAERDKLSVLYNEAQEELSALRKESTQTT 558
Query: 230 A-----SFIEERRA-----RENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTE 279
A S +E+ + + +++ L +K+ E + + +++
Sbjct: 559 APHNIVSLMEKEKELALSDLRRIMAEKEALREKLEHIEEVSLFGKSELEKTIEHLTCVNH 618
Query: 280 TLKLRRKETSTAEMEYQSGVTAVVEKVK-SAVRCSHVWDITSRFLAQRNT----EENLEL 334
L+ + E + + + + ++ K+K A + SHV +S + N+ E L+
Sbjct: 619 QLESEKYELKSKVLIMKETIESLENKLKVQAQKFSHVAGDSSHQKTEVNSLRIVNEQLQR 678
Query: 335 QMEDCEER----RVQLKALVKQLE-LEEAVLKFRQKPSSISFKS-VEKKMTDMLKEEEER 388
++D + R R +L++ Q++ LEE + + K +S ++ V KK ++ +E++
Sbjct: 679 SVDDYQHRLSIKRGELESAQAQIKILEEKIDELNLKMTSQDEEAHVMKKTIGVIDKEKDF 738
Query: 389 LQLAHSNMTKG----QELLLTIQMGIDNLYVRLMGITLPATQ-REVVLSNTLDLNS---- 439
LQ T+ QE L + + + + + Q +E +++ ++NS
Sbjct: 739 LQETVDEKTEKIANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQ 798
Query: 440 ---------------KLAYCEGK-----LTYLADRVQMVSRTEEGDTKVRDTLESSTLME 479
++A+ E + L +A Q +S E + V++ E + +
Sbjct: 799 LDAAHKELDEVGRSREIAFKENRRLQDDLATMARENQEISL--ELEAAVQEKEEMKSRVH 856
Query: 480 KYNTRIS--------FENREEDMIDTFQ 499
KY T +S E +D++D FQ
Sbjct: 857 KYITEVSRWESLMAAKEKENQDLLDRFQ 884
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 55.5 bits (132), Expect = 1e-07
Identities = 109/535 (20%), Positives = 217/535 (40%), Gaps = 57/535 (10%)
Query: 1 MRRHSETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWA 60
+ + ++ V+ T ++KT+ L+E + +++ + N D K T L + + +
Sbjct: 886 LEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERL--- 942
Query: 61 LAKKYDQWTISKACGKNLPLRL-AHCRSTMEVVREK---LRKYVFDRVNMHNLL---IHL 113
+D+ + + K L +L + + ++E+ EK L + + N + L +
Sbjct: 943 ---LHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKT 999
Query: 114 VRRRGQKLESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYL 173
V++ + L+ Q E ++S P S E+ + + ++ + K ++I + +
Sbjct: 1000 VKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQ 1059
Query: 174 DLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFI 233
LKT L + + LQ ++ + + + Q+ + T K Q E S +
Sbjct: 1060 AEKQALKTQLKQLETQNNNLQAQIL--ALQRQTVSLQEQNTTLQTQNAKL---QVENSTL 1114
Query: 234 EERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLD--FPSNLMSTETLKLRRKETSTA 291
+ N Q LI + + +E + + DL + S + E L+L + ++
Sbjct: 1115 NSQSTSLMNQNAQL-LIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQAS- 1172
Query: 292 EMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVK 351
EY+S + S+ ++ +NLE++ D E+R QL
Sbjct: 1173 --EYES--------------------LISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKG 1210
Query: 352 QLELEEAVLKFRQKPSSISFKSVEKKMTDMLK--EEEERLQLAHSNMTKGQELLLTIQMG 409
QLE E +LK Q+ + K+ E + K E +RL +S + K E+L T
Sbjct: 1211 QLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKN 1270
Query: 410 IDNLYVRLMGITLPATQREVVLSNTLDLNSKLAYCEGKLTYLADRV-QMVSRTEEGDTKV 468
+ +L L L T+ E S + +L KL + + Q+ EE + +
Sbjct: 1271 LKSL---LNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHL 1327
Query: 469 RDTLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIE 523
D ++ TLM + T + +D+ Q Y+ E++RQ ++L E
Sbjct: 1328 LDQIQ--TLMLQNRTLLEQNMESKDLFHVEQ-----RQYIDKLNELRRQKEKLEE 1375
Score = 39.7 bits (91), Expect = 0.007
Identities = 71/348 (20%), Positives = 142/348 (40%), Gaps = 62/348 (17%)
Query: 76 KNLPLRLAHCRSTMEVVREKLRKYV--FDRVNMH-NLLIHLVRRRGQ----------KLE 122
K+L A T+E +RE + + ++ N H N + +R+R Q + E
Sbjct: 529 KDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKE 588
Query: 123 SMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTV 182
+ L + SK E QI ++LE+ EK + + L+
Sbjct: 589 NKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG---------------ERAEELENE 633
Query: 183 LAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARENR 242
L E + LQ + N + IT E + Q + E R +
Sbjct: 634 LHHLEKENELLQKKITN---------------LKITCEKIEALEQENSELERENRKLKKT 678
Query: 243 LNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNL-------MSTETLKLRRKETSTAEMEY 295
L+ K L ++ + E E + + +L+ N+ M L+L KE + + +
Sbjct: 679 LDSFKNLTFQLESLE-KENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 296 QSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLEL 355
+ G+ E +K++ + + +++ + L N + L+ +E+ ++ QL++ ++ LE+
Sbjct: 738 KKGL----ELLKASFKKTERLEVSYQGLDIEN--QRLQKTLENSNKKIQQLESELQDLEM 791
Query: 356 EEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELL 403
E L+ + IS K +E+ L++E + L+ S + K ++ L
Sbjct: 792 ENQTLQKNLEELKISSKRLEQ-----LEKENKSLEQETSQLEKDKKQL 834
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 55.1 bits (131), Expect = 2e-07
Identities = 100/541 (18%), Positives = 221/541 (40%), Gaps = 64/541 (11%)
Query: 8 DVEEQTQELKTITQLQEQC------RALQIQGVKENMDQNKATLALLRSNIRRGAQDWAL 61
+++++++EL IT +++ + ++QG+ E + + K LA +SN + Q++
Sbjct: 762 EIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQN 821
Query: 62 AKKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKL 121
K T+ + E+ K V + N I + + QK
Sbjct: 822 FK------------------------TLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKF 857
Query: 122 ES----MQLELD-SLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLL 176
+S ++ EL + + ++E L + QL+ +E + T + L + L
Sbjct: 858 DSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKL 917
Query: 177 DYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEER 236
+ E D L+ L + E +K D + + + + +R + +E
Sbjct: 918 QQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLR----NALESL 973
Query: 237 RARENRLNQQKKLIDK-----IH----TKETSEKYRRGQMDLDFPSNLMSTETLKLRRKE 287
+ + +N K I + +H T ET +++++ + +D +L + T L
Sbjct: 974 KQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADV 1033
Query: 288 TSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLK 347
+E Q + +++++ K+ ++ I + + + +EN+E+ +E+ EE R+
Sbjct: 1034 KDNEIIEQQRKIFSLIQE-KNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGD 1092
Query: 348 ALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQ 407
L KQ E+ ++K +I + + D L E EE+L+ + + Q+ LL +Q
Sbjct: 1093 ELKKQQEIVA-----QEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQ 1147
Query: 408 MGIDNLYVRLMGITLPATQ---REVVLSNTLDLNSKLAYCEGKLTYLADRVQMVSRTEEG 464
+ + ++ I + +E+ L + +LA KL + V+ +++
Sbjct: 1148 EEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQ---KLNENYEEVKSITK---- 1200
Query: 465 DTKVRDTLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIEG 524
+ KV L+ S E+ + R E + T + + H ++ E + +R +
Sbjct: 1201 ERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSE 1260
Query: 525 K 525
K
Sbjct: 1261 K 1261
Score = 46.2 bits (108), Expect = 7e-05
Identities = 105/532 (19%), Positives = 214/532 (40%), Gaps = 56/532 (10%)
Query: 1 MRRHSETDVEEQTQELKTITQLQEQCRAL-QIQGVKENMDQNKATLALLRSNIRRGAQDW 59
++ S+ E+Q Q L ++ E + + +I+ +K + + TL + + AQ
Sbjct: 1129 LKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQK- 1187
Query: 60 ALAKKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFD----------------- 102
L + Y++ K+ K + L + + E R+ LR Y+ +
Sbjct: 1188 -LNENYEE---VKSITKERKV-LKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHI 1242
Query: 103 RVNMHNLLIHLVRRRGQKLESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKI 162
+ H I +RR + + + L +EE+ +L ++L N+++
Sbjct: 1243 HLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQ 1302
Query: 163 ITSQNIHLLYLDLLDYLKTVLAGYPIELDKL-------QNLVVNYCSELSDMKIMSQDAM 215
T + LL T LA +E +L Q + + E ++K + +
Sbjct: 1303 ETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALE 1362
Query: 216 MITDEVKRNMRQREASFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNL 275
+ D++K ++R+ A E + +E LN ++K D TK SE + D S L
Sbjct: 1363 VKHDQLKEHIRETLAKIQESQSKQEQSLNMKEK--DNETTKIVSEMEQFKPKD----SAL 1416
Query: 276 MSTETLKL---RRKETSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENL 332
+ E L +R + S EM+ +V ++ R V S L + N +E +
Sbjct: 1417 LRIEIEMLGLSKRLQESHDEMK------SVAKEKDDLQRLQEVLQSESDQLKE-NIKEIV 1469
Query: 333 ELQMEDCEERRVQLKALVKQLE-LEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQL 391
+E EE +V L +Q E + E + +K + IS +++K++ + + + ++Q
Sbjct: 1470 AKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEIS--TIQKQLEAINDKLQNKIQE 1527
Query: 392 AHSNMTKGQELLLTIQMGIDNLYVRLMGITLPATQREVVLSNTLDLNSKLAYCEGKLTYL 451
+ +E I+ I + ++ + R+ S + SK+ +L
Sbjct: 1528 IYE-----KEEQFNIKQ-ISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQES 1581
Query: 452 ADRVQMVSRTEEGDTKVRDTLESSTLMEKYNTRISFENREEDMIDTFQFPDM 503
+ +Q++ + +E +V++ L+ K NT+ +E +QF M
Sbjct: 1582 QEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKM 1633
Score = 30.0 bits (66), Expect = 5.5
Identities = 63/368 (17%), Positives = 142/368 (38%), Gaps = 51/368 (13%)
Query: 119 QKLESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDY 178
++LE + LE + + D + L ++++++N + + +++ + + L +L
Sbjct: 357 KQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAK 416
Query: 179 LKTVLAGYPIELDKLQN-------------------LVVNYCSELSDMKIMSQDAMMITD 219
K + +++K++N L +N E+ + D T
Sbjct: 417 RKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTL 476
Query: 220 EVKRNMRQREASFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTE 279
+ + A+ + + E+ LN + D + + + +M+L E
Sbjct: 477 DTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDE 536
Query: 280 TLKLRRKETSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDC 339
L RK EM+ + + +K+ V+ + V++ ++ E L ++E
Sbjct: 537 FEALERKTKKDQEMQ----LIHEISNLKNLVKHAEVYN--------QDLENELSSKVELL 584
Query: 340 EERRVQLKALVKQLELEEAVLKFRQKPSSISFKSVE--KKMTDML----------KEEEE 387
E+ Q+K L + ++ ++ L+ + S S +S+E K+M L K E
Sbjct: 585 REKEDQIKKLQEYIDSQK--LENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESA 642
Query: 388 RLQLAHSNMTKGQELLLTIQMGIDNLYVRLMGITLPATQREVVLSNTLDLNSKLAYCEGK 447
L+ + + + + L T ++N I L +Q E +DL +L +
Sbjct: 643 FLRSENLELKEKMKELATTYKQMEN------DIQLYQSQLEAKKKMQVDLEKELQSAFNE 696
Query: 448 LTYLADRV 455
+T L +
Sbjct: 697 ITKLTSLI 704
Score = 29.3 bits (64), Expect = 9.4
Identities = 66/316 (20%), Positives = 137/316 (43%), Gaps = 43/316 (13%)
Query: 122 ESMQLELDSLRSQPDASKE-ELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLK 180
+ M+ ++ +SQ +A K+ ++ L + ++ N I K +TS + DLL L+
Sbjct: 663 KQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITK-----LTSLIDGKVPKDLLCNLE 717
Query: 181 TVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARE 240
L G +L K N V L + I+ + + EV+R ++ I+++
Sbjct: 718 --LEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKE-----IQDKSEEL 770
Query: 241 NRLNQQK-KLIDKIHTKETS-----EKYRRGQMDL-DFPSNLMSTETLKLRRKETSTAEM 293
+ + +K KL ++ KE+ E+ + + DL SN ST+ + T M
Sbjct: 771 HIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQ---EFQNFKTLHM 827
Query: 294 EYQSGVTAVVEKVK----SAVRCSHVWDITSRFLAQRNTE-----ENLELQMEDCEERRV 344
+++ V+E+ + V S L TE + L+ + + +ER
Sbjct: 828 DFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLN 887
Query: 345 QLKALVKQLELEEAVLKFRQKPSSISFKSVEKKM---------TDMLKEEEERLQLAHSN 395
+++ L +QLE ++ L+ ++ ++ + +++ + D LK+ +E LQ+
Sbjct: 888 EMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQ 947
Query: 396 MTKGQELLLTIQMGID 411
+ ++ T+ M ID
Sbjct: 948 LK--SDIHDTVNMNID 961
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 54.7 bits (130), Expect = 2e-07
Identities = 84/398 (21%), Positives = 162/398 (40%), Gaps = 40/398 (10%)
Query: 120 KLESMQLELDSLRSQPDASKEELR--LLQIIRQLENNIEKTMIKIITSQNIHLLYL-DLL 176
++E++Q + DS R+ E LR L+++I++ EN++E K+ +++ HL+ + D L
Sbjct: 627 EIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTL 686
Query: 177 DYLKTVLAGYPIELDKLQ-------NLVVNYCSEL--SDMKIMSQDAMMITDEVKRNMRQ 227
+ L+ EL+ LQ ++ N+ S+L ++ K++ DA +R+
Sbjct: 687 NKLQEAEIKVK-ELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDA----------LRK 735
Query: 228 REASFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKE 287
+ E + +L +K I + ++ +E + + + + L+ E
Sbjct: 736 ASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSE 795
Query: 288 TS----TAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEEN-LELQMEDCEER 342
S T E E Q E + AV T L Q+ + N L +E E
Sbjct: 796 VSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLREN 855
Query: 343 RVQLKALVKQL-ELEEAVLKFRQK---------PSSISFKSVEKKMTDMLKEEEERLQLA 392
++A ++ E EE ++K ++K S S KM D L+ +E ++
Sbjct: 856 LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEEL 915
Query: 393 HSNMTKGQELLLTIQMGIDNLYVRLMGITLPATQREVVLSNTLDLNSKLAYCEGKLTYLA 452
+TK E +Q I+++ V+ A ++ +L KL+ E K+
Sbjct: 916 QLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHE--EEKKELERKLSDLEKKMETSH 973
Query: 453 DRVQMVSRTEEGDTKVRDTLESSTLMEKYNTRISFENR 490
++ Q + E T T L T + E++
Sbjct: 974 NQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDK 1011
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 54.7 bits (130), Expect = 2e-07
Identities = 84/398 (21%), Positives = 162/398 (40%), Gaps = 40/398 (10%)
Query: 120 KLESMQLELDSLRSQPDASKEELR--LLQIIRQLENNIEKTMIKIITSQNIHLLYL-DLL 176
++E++Q + DS R+ E LR L+++I++ EN++E K+ +++ HL+ + D L
Sbjct: 662 EIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTL 721
Query: 177 DYLKTVLAGYPIELDKLQ-------NLVVNYCSEL--SDMKIMSQDAMMITDEVKRNMRQ 227
+ L+ EL+ LQ ++ N+ S+L ++ K++ DA +R+
Sbjct: 722 NKLQEAEIKVK-ELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDA----------LRK 770
Query: 228 REASFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKE 287
+ E + +L +K I + ++ +E + + + + L+ E
Sbjct: 771 ASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSE 830
Query: 288 TS----TAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEEN-LELQMEDCEER 342
S T E E Q E + AV T L Q+ + N L +E E
Sbjct: 831 VSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLREN 890
Query: 343 RVQLKALVKQL-ELEEAVLKFRQK---------PSSISFKSVEKKMTDMLKEEEERLQLA 392
++A ++ E EE ++K ++K S S KM D L+ +E ++
Sbjct: 891 LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEEL 950
Query: 393 HSNMTKGQELLLTIQMGIDNLYVRLMGITLPATQREVVLSNTLDLNSKLAYCEGKLTYLA 452
+TK E +Q I+++ V+ A ++ +L KL+ E K+
Sbjct: 951 QLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHE--EEKKELERKLSDLEKKMETSH 1008
Query: 453 DRVQMVSRTEEGDTKVRDTLESSTLMEKYNTRISFENR 490
++ Q + E T T L T + E++
Sbjct: 1009 NQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDK 1046
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 53.5 bits (127), Expect = 5e-07
Identities = 88/422 (20%), Positives = 172/422 (40%), Gaps = 58/422 (13%)
Query: 10 EEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQD------WALAK 63
E +T E+K L E+ RA Q + +K ++Q L S + + QD LA+
Sbjct: 1068 EAETDEIKI---LLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAE 1124
Query: 64 KYDQWTISK-ACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLE 122
TI K C L ++ +++ +L K ++HN + + +++
Sbjct: 1125 LRTLMTIEKDQCISEL---ISRHEEESNILKAELNKVT----SLHNQAFEIEKNLKEQII 1177
Query: 123 SMQLELDSLRSQPDASKEELRLLQIIRQLE---NNIEKTMIKIITSQN------IHLLYL 173
+Q +LDS S + K+E ++ Q + E N+EK K+++SQ I L
Sbjct: 1178 ELQSKLDSELSALERQKDE-KITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNC 1236
Query: 174 DLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQ-------DAMMITDEVKRNMR 226
+ + ++T L + +E + ++ ++ L + S D+ + E++ ++
Sbjct: 1237 EKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQ 1296
Query: 227 QREASFIEERRARENRLNQQKKLI---------DKIHTKETSEKYRRGQMDLDFPSNLMS 277
+ +A F+E+ +E R N++ + + +T T EK R+ + D L S
Sbjct: 1297 EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKS 1356
Query: 278 TETLKLRRK-------ETSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFL----AQR 326
T + R K E +E + + V K++S+ + T+ L A
Sbjct: 1357 TMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPE 1416
Query: 327 NTEENLELQMEDCEERRVQLKALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEE 386
E+ +E +E RV + ++E + ++ I + T LKEEE
Sbjct: 1417 LPGESDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIML----LERTLQLKEEE 1472
Query: 387 ER 388
+
Sbjct: 1473 NK 1474
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 53.5 bits (127), Expect = 5e-07
Identities = 88/422 (20%), Positives = 172/422 (40%), Gaps = 58/422 (13%)
Query: 10 EEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQD------WALAK 63
E +T E+K L E+ RA Q + +K ++Q L S + + QD LA+
Sbjct: 1068 EAETDEIKI---LLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAE 1124
Query: 64 KYDQWTISK-ACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLE 122
TI K C L ++ +++ +L K ++HN + + +++
Sbjct: 1125 LRTLMTIEKDQCISEL---ISRHEEESNILKAELNKVT----SLHNQAFEIEKNLKEQII 1177
Query: 123 SMQLELDSLRSQPDASKEELRLLQIIRQLE---NNIEKTMIKIITSQN------IHLLYL 173
+Q +LDS S + K+E ++ Q + E N+EK K+++SQ I L
Sbjct: 1178 ELQSKLDSELSALERQKDE-KITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKLNC 1236
Query: 174 DLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQ-------DAMMITDEVKRNMR 226
+ + ++T L + +E + ++ ++ L + S D+ + E++ ++
Sbjct: 1237 EKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQ 1296
Query: 227 QREASFIEERRARENRLNQQKKLI---------DKIHTKETSEKYRRGQMDLDFPSNLMS 277
+ +A F+E+ +E R N++ + + +T T EK R+ + D L S
Sbjct: 1297 EEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKS 1356
Query: 278 TETLKLRRK-------ETSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFL----AQR 326
T + R K E +E + + V K++S+ + T+ L A
Sbjct: 1357 TMQQQERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPE 1416
Query: 327 NTEENLELQMEDCEERRVQLKALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEE 386
E+ +E +E RV + ++E + ++ I + T LKEEE
Sbjct: 1417 LPGESDRSAVETADEGRVDSAMETSMMSVQENIHMLSEEKQRIML----LERTLQLKEEE 1472
Query: 387 ER 388
+
Sbjct: 1473 NK 1474
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 53.5 bits (127), Expect = 5e-07
Identities = 100/541 (18%), Positives = 228/541 (42%), Gaps = 73/541 (13%)
Query: 7 TDVEEQTQELKT-ITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWALAKKY 65
++VE + Q LK QLQ+Q + G++ + N+ LL + + G L K+
Sbjct: 382 SEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRL-KEQ 440
Query: 66 DQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLESMQ 125
Q + K K ++A + + + E+L++ V + + + L ++ ++ Q
Sbjct: 441 RQLSSEKLMDKEQ--QVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQ 498
Query: 126 LELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTVLAG 185
LR + ++ LR + Q N+E + K + +NI LL + D + AG
Sbjct: 499 STTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQK--SKENISLLEKEREDLYAKIQAG 556
Query: 186 YPI-----ELDKLQNLVVNYCSELSD-MKIMSQDAMMITDEVKRNMRQREASFIEERRAR 239
+L + + + ++L++ +K S+ + + +++++A RA
Sbjct: 557 EGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHL----RAA 612
Query: 240 ENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSN---LMSTETLKLRRK-----ETSTA 291
++R+ + +++++++ K + Q+D+ + L+S E K ++ TA
Sbjct: 613 QDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTA 672
Query: 292 EMEYQ------SGVTAVVEKVKSAVR-----CS----HVWDITSRFLAQRNTEENLELQM 336
+ Q + +T +++V + ++ CS H+ + ++L+ E LE Q+
Sbjct: 673 QNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQI 732
Query: 337 EDCEERRVQLKA-------------------------LVKQLELEEAVL---KFRQKPSS 368
+ E +++KA L KQLE+E+ ++ + + S
Sbjct: 733 KKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKS 792
Query: 369 ISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQMGIDNLYVRLMGITLPATQRE 428
+ +S+++K+T K+EEE+ L T QE + + + + + + ++E
Sbjct: 793 EALESIKQKLT---KQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKE 849
Query: 429 VVLSNTLDLNSKLAYCEGKLTYLADRVQMVSRTEEGDTKVRDTLESSTLMEKYNTRISFE 488
+++ + KL+ L + + ++G + D LE + K+ ++ E
Sbjct: 850 ALMTELSTVKDKLSKVSDSLK--NSKSEFEKENQKGKAAILD-LEKTCKELKHQLQVQME 906
Query: 489 N 489
N
Sbjct: 907 N 907
Score = 39.3 bits (90), Expect = 0.009
Identities = 70/370 (18%), Positives = 144/370 (38%), Gaps = 28/370 (7%)
Query: 119 QKLESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDY 178
QKL + E L+ + +E ++ +L N I+ T+ ++ Q + + L+
Sbjct: 800 QKLTKQEEEKQILKQDFETLSQETKIQH--EELNNRIQTTVTEL---QKVKMEKEALMTE 854
Query: 179 LKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRA 238
L TV D L+N + E K D E+K ++ + + ++E++
Sbjct: 855 LSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKE 914
Query: 239 RENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSG 298
+ L ++K+ ++ + S + + Q N + L+ E + + +
Sbjct: 915 LKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQ 974
Query: 299 VTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLE--LE 356
+ A+ ++K AV L + E L+ Q+ + K + L+ E
Sbjct: 975 IEALQGELKIAV------------LQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYE 1022
Query: 357 EAVLKFRQKPSSISFKSVEKKMTDM-LKEEEERLQLAHSNMTKGQELLLTIQMGIDNLYV 415
++ F+Q S + E T LK EE+L LA ++ + + I L
Sbjct: 1023 KSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKT 1082
Query: 416 RLMGITLPATQREVVLSNTL----DLNSKLAYCEGKL----TYLADRVQMVSRTEEGDTK 467
+ + ++E L D+ + + E +L + LA+ ++ R E+ TK
Sbjct: 1083 AKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITK 1142
Query: 468 VRDTLESSTL 477
+ + L+S L
Sbjct: 1143 LNEELKSHKL 1152
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 52.8 bits (125), Expect = 8e-07
Identities = 82/400 (20%), Positives = 172/400 (43%), Gaps = 42/400 (10%)
Query: 17 KTITQLQEQCRAL--QIQGVKENMDQNKATLALLRSNIRRGAQDWALAKKYDQWTIS-KA 73
+T+ + +E+ L QIQ +++ + KA L LL ++++ Q+ L ++ Q ++
Sbjct: 1428 QTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRS 1487
Query: 74 CGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLESMQLELDSLRS 133
++LP+ + + V RE++R+ DR N+L H + +LE ++S R
Sbjct: 1488 VLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQL----LELEKKDQMIESQRG 1543
Query: 134 QPDASKEELRLLQIIR-QLENN-----IEKTMIKII----TSQNIHLLYLDL-LDYLKTV 182
Q K++L L+ + +LE N ++ +IK + +Q + L +L L L+
Sbjct: 1544 QVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQE 1603
Query: 183 LAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARENR 242
L ++ L++ EL + Q+ ++++ RQ+E ++ R+
Sbjct: 1604 LQAQSSQIHDLESHSTVLARELQE---RDQEVKSQREQIEELQRQKE-HLTQDLERRDQE 1659
Query: 243 LNQQKKLIDKI------HTKETSEKYRRGQMDLDFPSNLMSTE-TLKLRRKETSTAEMEY 295
L QK+ I + TK E + ++ L ++T+ L R E +
Sbjct: 1660 LMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKA 1719
Query: 296 QSG----VTAVVEKVKSAVRC--SHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKAL 349
Q G + ++ + V C H+ ++ + ++ LE Q++ + + L
Sbjct: 1720 QRGSLEHMKLILRDKEKEVECQQEHIHEL-------QELKDQLEQQLQGLHRKVGETSLL 1772
Query: 350 VKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERL 389
+ Q E E VL+ + + + + E+ + L E + L
Sbjct: 1773 LSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRAL 1812
Score = 38.5 bits (88), Expect = 0.016
Identities = 76/397 (19%), Positives = 168/397 (42%), Gaps = 43/397 (10%)
Query: 66 DQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQK---LE 122
+Q + A GK L LA T+ E++ + + L ++R + LE
Sbjct: 1407 EQGELKVAQGKALQENLALLTQTLAEREEEVE-------TLRGQIQELEKQREMQKAALE 1459
Query: 123 SMQLELDSLRSQPDASKEELRLLQIIRQLENNI-----EKTMIKIITSQNIHLLYLDLLD 177
+ L+L + D +E+++ L+ R + ++ E+ + + I L D +
Sbjct: 1460 LLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDR-E 1518
Query: 178 YLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERR 237
+ VL +EL+K ++ + ++ D+K + E++ N + E +++
Sbjct: 1519 TQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMEC---QQKL 1575
Query: 238 ARENRLNQQKKLIDKIH-TKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQ 296
+E ++ + + H T + E+ + Q +L S T+ R + E++ Q
Sbjct: 1576 IKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQ 1635
Query: 297 SGVTAVVEKVKSAVRCSHVWDITSR---FLAQRNTEENLELQM--------EDCEERRVQ 345
+++ K + D+ R + Q+ + LE Q ED E+ ++
Sbjct: 1636 REQIEELQRQKEHL----TQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLS 1691
Query: 346 LKALVKQLELEEAVLKFRQK----PSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQE 401
L+ ++L + +++ R + PS S+E M +L+++E+ ++ ++ + QE
Sbjct: 1692 LRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEH-MKLILRDKEKEVECQQEHIHELQE 1750
Query: 402 LLLTIQMGIDNLYVRLMGITLPATQRE---VVLSNTL 435
L ++ + L+ ++ +L +QRE VVL L
Sbjct: 1751 LKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQL 1787
Score = 33.5 bits (75), Expect = 0.50
Identities = 86/435 (19%), Positives = 189/435 (43%), Gaps = 56/435 (12%)
Query: 86 RSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLESMQLELDSLRSQPDASKEELRLL 145
R ++ RE+LR+ + L R R +E +QL+ DS + Q + +EEL L
Sbjct: 465 RELLQKAREELRQ------QLEVLEQEAWRLRRVNVE-LQLQGDSAQGQKEEQQEELHL- 516
Query: 146 QIIRQLENNIEKTM-IKIITSQNIHLLYLDLLDYLKTV-LAGYPIELDKLQNLVVNYCSE 203
+R+ E E M ++ S+++ L + L + L++ L G + ++ + +E
Sbjct: 517 -AVRERERLQEMLMGLEAKQSESLSEL-ITLREALESSHLEGELLRQEQTEVTAALARAE 574
Query: 204 LSDMKIMSQDAMMITDEVKRNMRQREASFIEERRAREN-RLNQQKKLIDK----IHTKET 258
S ++ S + + T+ + S + E A + LNQQ +++ + ++
Sbjct: 575 QSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRME 634
Query: 259 SEKYRRGQMDLDFPSNLMSTETL---------KLRRKETSTAEMEYQSGVTAVVEKVKSA 309
+ + R + +D E L +L++ E + AE+ Q+ + + E+ +
Sbjct: 635 AAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAEL--QADLRDIQEEKE-- 690
Query: 310 VRCSHVWDITSRFLAQRNTEENLELQMEDC-EERRVQLKALVKQLELEEAVLKFRQKPSS 368
+I + R+ +E Q+E +E + Q + L + ++ +EA+++ +
Sbjct: 691 -------EIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVR-EKAALE 742
Query: 369 ISFKSVEKKMTDMLKEEE---ERLQLAHSNMTKGQELLLTIQMGIDNLYVRLMGITLPAT 425
+ ++VE+ D+ ++ + +L S++ + Q+ I++ L V++ +T
Sbjct: 743 VRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVT---Q 799
Query: 426 QREVVLSNT----LDLNSKLAYCEGKLTYLADRVQMVSRTEEGDT-----KVRDTLESST 476
+EV+ L+L+++ + E + A Q+ +EG T K E +
Sbjct: 800 AKEVIQGEVRCLKLELDTERSQAEQERDAAAR--QLAQAEQEGKTALEQQKAAHEKEVNQ 857
Query: 477 LMEKYNTRISFENRE 491
L EK+ S+ +E
Sbjct: 858 LREKWEKERSWHQQE 872
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 52.4 bits (124), Expect = 1e-06
Identities = 106/534 (19%), Positives = 215/534 (40%), Gaps = 56/534 (10%)
Query: 1 MRRHSETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWA 60
+ + ++ V+ T ++KT+ L+E + +++ + N D K T L + + +
Sbjct: 886 LEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD 945
Query: 61 LAKKYDQWTISKACGKNLPLRLAHCRSTMEVVREK---LRKYVFDRVNMHNLL---IHLV 114
D++ + ++ ++ + ++E+ EK L + + N + L + V
Sbjct: 946 EQSTDDRYKLLESKLEST------LKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTV 999
Query: 115 RRRGQKLESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLD 174
++ + L+ Q E ++S P S E+ + + ++ + K ++I + +
Sbjct: 1000 KKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQA 1059
Query: 175 LLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIE 234
LKT L + + LQ ++ + + + Q+ + T K Q E S +
Sbjct: 1060 EKQALKTQLKQLETQNNNLQAQIL--ALQRQTVSLQEQNTTLQTQNAKL---QVENSTLN 1114
Query: 235 ERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLD--FPSNLMSTETLKLRRKETSTAE 292
+ N Q LI + + +E + + DL + S + E L+L + ++
Sbjct: 1115 SQSTSLMNQNAQL-LIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQAS-- 1171
Query: 293 MEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQ 352
EY+S + S+ ++ +NLE++ D E+R QL Q
Sbjct: 1172 -EYES--------------------LISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQ 1210
Query: 353 LELEEAVLKFRQKPSSISFKSVEKKMTDMLK--EEEERLQLAHSNMTKGQELLLTIQMGI 410
LE E +LK Q+ + K+ E + K E +RL +S + K E+L T +
Sbjct: 1211 LEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNL 1270
Query: 411 DNLYVRLMGITLPATQREVVLSNTLDLNSKLAYCEGKLTYLADRV-QMVSRTEEGDTKVR 469
+L L L T+ E S + +L KL + + Q+ EE + +
Sbjct: 1271 KSL---LNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLL 1327
Query: 470 DTLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIE 523
D ++ TLM + T + +D+ Q Y+ E++RQ ++L E
Sbjct: 1328 DQIQ--TLMLQNRTLLEQNMESKDLFHVEQ-----RQYIDKLNELRRQKEKLEE 1374
Score = 40.8 bits (94), Expect = 0.003
Identities = 98/486 (20%), Positives = 190/486 (39%), Gaps = 77/486 (15%)
Query: 76 KNLPLRLAHCRSTMEVVREKLRKYV--FDRVNMH-NLLIHLVRRRGQ----------KLE 122
K+L A T+E +RE + + ++ N H N + +R+R Q + E
Sbjct: 529 KDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKE 588
Query: 123 SMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTV 182
+ L + SK E QI ++LE+ EK + + L+
Sbjct: 589 NKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKG---------------ERAEELENE 633
Query: 183 LAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARENR 242
L E + LQ + N + IT E + Q + E R +
Sbjct: 634 LHHLEKENELLQKKITN---------------LKITCEKIEALEQENSELERENRKLKKT 678
Query: 243 LNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNL-------MSTETLKLRRKETSTAEMEY 295
L+ K L ++ + E E + + +L+ N+ M L+L KE + + +
Sbjct: 679 LDSFKNLTFQLESLE-KENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL 737
Query: 296 QSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLEL 355
+ G+ E +K++ + + +++ + L N + L+ +E+ ++ QL++ ++ LE+
Sbjct: 738 KKGL----ELLKASFKKTERLEVSYQGLDIEN--QRLQKTLENSNKKIQQLESELQDLEM 791
Query: 356 EEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQMGIDNLYV 415
E L+ + IS K +E+ L++E + L+ S + K ++ Q+ +N +
Sbjct: 792 ENQTLQKNLEELKISSKRLEQ-----LEKENKSLEQETSQLEKDKK-----QLEKENKRL 841
Query: 416 RLMGITLPATQRE--VVLSNTLDLNSKLA-----YCEG--KLTYLADRVQMVSRTEEGDT 466
R T E V + N N L+ Y E +L L + + + D
Sbjct: 842 RQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDI 901
Query: 467 KVRDTLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIEGKL 526
K TL + EK T+ N E + + ++ + + +L+E KL
Sbjct: 902 KTLVTLREDLVSEKLKTQ-QMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKL 960
Query: 527 KAAKKK 532
++ KK
Sbjct: 961 ESTLKK 966
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 51.6 bits (122), Expect = 2e-06
Identities = 88/412 (21%), Positives = 180/412 (43%), Gaps = 71/412 (17%)
Query: 2 RRHSETDVEEQTQELKTITQLQEQCRALQIQG-VKENMDQNKATLALLRSNIRRGAQDWA 60
R++ +T EQ + + + Q R+ + Q VKE + NK+ L NI A
Sbjct: 352 RKNVQTLRAEQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAA 411
Query: 61 LAKKYDQWTISKACGKNLPLRL--AHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRG 118
+ Q I K + P +L H R T++ E+ VNM L ++
Sbjct: 412 AGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEK-----TNVNM------LYKKNR 460
Query: 119 QKLESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDY 178
++LE + + K+E+ +QLE ++ +K T++N D ++
Sbjct: 461 EELERKEKQY----------KKEVE----AKQLEPTVQSLEMKSKTARNTP--NWDFHNH 504
Query: 179 LKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDE--VKRNMRQREASFIEER 236
++++ L+ C +D+ I+ Q+ + ++ K N ++ ++E
Sbjct: 505 ------------EEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKET 552
Query: 237 RARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRR-KETSTAEME- 294
A L + KL +++ T ET+ +Y++ DL + ++ E LK + K+ A++E
Sbjct: 553 NA---ALEKYIKLNEEMIT-ETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIES 608
Query: 295 YQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQ--LKALVKQ 352
YQS + A + K +V+ TE NL+L +E ++ VQ + + + +
Sbjct: 609 YQSRLAAAISKHSESVK----------------TERNLKLALERTQDVSVQVEMSSAISK 652
Query: 353 LELEEAVLKFRQKPSSISFKSVE---KKMTDMLKEEEERLQLAHSNMTKGQE 401
++ E L + + I F +++ +K D L+++ L+ +N+++ Q+
Sbjct: 653 VKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQ 704
>gi|187761324 shootin1 isoform a [Homo sapiens]
Length = 631
Score = 51.2 bits (121), Expect = 2e-06
Identities = 49/230 (21%), Positives = 108/230 (46%), Gaps = 28/230 (12%)
Query: 125 QLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTVLA 184
Q ++ LR Q + +EE ++L I +LEN ++ ++++I N + KTVL
Sbjct: 141 QKQIKELRDQIVSVQEEKKILAI--ELEN-LKSKLVEVIEEVN-------KVKQEKTVLN 190
Query: 185 GYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARENRLN 244
+E Q V+ C+ +S + + + M + E+++++R++ SF +E +N+L
Sbjct: 191 SEVLE----QRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLK 246
Query: 245 QQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSGVTAVVE 304
+Q L+ + + Q+ N T+ L+ R +++Q V + E
Sbjct: 247 RQSHLLLQSSIPDQ-------QLLKALDENAKLTQQLEEER-------IQHQQKVKELEE 292
Query: 305 KVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLE 354
++++ + ++ + ++ LEL+ ++ EE+ LK V +L+
Sbjct: 293 QLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQ 342
>gi|50511340 shootin1 isoform b [Homo sapiens]
Length = 456
Score = 51.2 bits (121), Expect = 2e-06
Identities = 49/230 (21%), Positives = 108/230 (46%), Gaps = 28/230 (12%)
Query: 125 QLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTVLA 184
Q ++ LR Q + +EE ++L I +LEN ++ ++++I N + KTVL
Sbjct: 141 QKQIKELRDQIVSVQEEKKILAI--ELEN-LKSKLVEVIEEVN-------KVKQEKTVLN 190
Query: 185 GYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARENRLN 244
+E Q V+ C+ +S + + + M + E+++++R++ SF +E +N+L
Sbjct: 191 SEVLE----QRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLK 246
Query: 245 QQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSGVTAVVE 304
+Q L+ + + Q+ N T+ L+ R +++Q V + E
Sbjct: 247 RQSHLLLQSSIPDQ-------QLLKALDENAKLTQQLEEER-------IQHQQKVKELEE 292
Query: 305 KVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLE 354
++++ + ++ + ++ LEL+ ++ EE+ LK V +L+
Sbjct: 293 QLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQ 342
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 50.8 bits (120), Expect = 3e-06
Identities = 75/388 (19%), Positives = 162/388 (41%), Gaps = 36/388 (9%)
Query: 31 IQGVKENMDQNKATLALLRSNIRRGAQDWALAKKYDQWTISKACGKNLPLRLAHCRSTME 90
IQ +KE + + TL + ++ G + AL++ T KA K L L T +
Sbjct: 1081 IQQLKEELQEKNVTLDVQIQHVVEGKR--ALSELTQGVTCYKAKIKELETIL----ETQK 1134
Query: 91 VVREKLRKYVFDRVNMHNLLIHLVRRRGQKLESMQLELDSLRSQPDASKEELRLLQIIRQ 150
V K D + ++++ L R + E +Q DS+++ D + +EL+L + I Q
Sbjct: 1135 VECSHSAKLEQDILEKESIILKLERNLKEFQEHLQ---DSVKNTKDLNVKELKLKEEITQ 1191
Query: 151 LENNIEKTMIKIITSQNIHLLYLDLLDYLKTVLA-------GYPIELDKLQNLVVNYCSE 203
L NN++ + + + LK L+ +L + + + +
Sbjct: 1192 LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEK 1251
Query: 204 LSD----MKIMSQDAMMITDEVK------RNMRQREASFIEERRARENRLNQQKKLIDKI 253
L+D +K + ++ ++ DE K + +++ +E ++ + Q K+ ++
Sbjct: 1252 LTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQ 1311
Query: 254 HTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSGVTAVVEKVKSAVRCS 313
+E ++Y R DL+ ++ E +++ +E ++E + A +E+V+
Sbjct: 1312 KVEEAIQQYERACKDLNVKEKII--EDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATEL 1369
Query: 314 HVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLELEEAVLKFRQKPSSISFKS 373
W L +N + + +E L K L++ + + QK ++ K
Sbjct: 1370 EKWKEKCNDLETKNNQRS-------NKEHENNTDVLGKLTNLQDELQESEQKYNADRKKW 1422
Query: 374 VEKKMTDMLKEEEERLQLAHSNMTKGQE 401
+E+KM ++ + +E + + M K E
Sbjct: 1423 LEEKMM-LITQAKEAENIRNKEMKKYAE 1449
Score = 35.4 bits (80), Expect = 0.13
Identities = 110/547 (20%), Positives = 206/547 (37%), Gaps = 130/547 (23%)
Query: 85 CRSTMEVVREKLRKYVFDR--VNMHNLL----------IHLV------RRRGQKLESMQL 126
C T+EV ++ K +R VN + L IH+ +++ +++
Sbjct: 773 CNETVEVPKDSKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIA 832
Query: 127 ELDSLRSQPDASKEELR--LLQIIRQLENNIEKTMIKIITSQNIHLLY---------LDL 175
E++ +R + + E LR LL I +L+N EK + Q +H L L
Sbjct: 833 EIEDIRVLQE-NNEGLRAFLLTIENELKN--EKEEKAELNKQIVHFQQELSLSEKKNLTL 889
Query: 176 LDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIM--SQDAMMITDEVKRNMRQREASFI 233
++ + + Y I + +L V ++ + KIM S + T + N+ Q +
Sbjct: 890 SKEVQQIQSNYDIAIAELH--VQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHT 947
Query: 234 EERRARENRLNQQKKLIDKIHTKETS-----EKYRRGQMDLDFPSNLMSTETLKLRRKET 288
+ R Q ID ++ ++ S + Q+DL L+S + + R +E
Sbjct: 948 KIDELRTLDSVSQISNIDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEP 1007
Query: 289 STAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKA 348
+ E + S + A+ E+ K V+ S Q+E+ E++ +L+A
Sbjct: 1008 NR-ENSFHSSIEAIWEECKEIVKAS----------------SKKSHQIEELEQQIEKLQA 1050
Query: 349 LVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQ-----LAHSNMT------ 397
VK + E LK ++ K D+LKE+E +Q L N+T
Sbjct: 1051 EVKGYKDENNRLKEKE----------HKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQ 1100
Query: 398 ---KGQELLLTIQMGIDNLYVRLMGI-TLPATQR-----------------EVVL----- 431
+G+ L + G+ ++ + T+ TQ+ ++L
Sbjct: 1101 HVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERN 1160
Query: 432 ------------SNTLDLNSKLAYCEGKLTYLADRVQ-----MVSRTEEGDTKVRDTLE- 473
NT DLN K + ++T L + +Q + + EE +T ++T +
Sbjct: 1161 LKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKL 1220
Query: 474 ----SSTLMEKYNTRISFENREEDMID---TFQFPDMDHSYVPSRAEIKRQAQRLIEGKL 526
S++ N + + +EED D V + R +L+ K+
Sbjct: 1221 KEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI 1280
Query: 527 KAAKKKK 533
+KKK
Sbjct: 1281 NELEKKK 1287
Score = 33.1 bits (74), Expect = 0.65
Identities = 88/465 (18%), Positives = 188/465 (40%), Gaps = 47/465 (10%)
Query: 7 TDVEEQTQELKTITQL---QEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWALAK 63
T + Q++K + QL +E+ + + +KE + + A L+++++R +D+A K
Sbjct: 1190 TQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLK 1249
Query: 64 KYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLES 123
++ T +K K + ++ R +++R K+ N L + Q+L+
Sbjct: 1250 --EKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI-----------NELEKKKNQCSQELDM 1296
Query: 124 MQLELDSLRSQPDASKEELRLLQIIRQLEN-NIEKTMIKIITSQNIHLLYLDLLDYLK-T 181
Q + L+ Q + K E + Q R ++ N+++ KII + L + +
Sbjct: 1297 KQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKE---KIIEDMRMTLEEQEQTQVEQDQ 1353
Query: 182 VLAGYPIELDKLQNLVVNYCSELSDMKIMSQ-----------DAMMITDEVKRNMRQREA 230
VL E+++L + + + +D++ + D + ++ +++ E
Sbjct: 1354 VLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQ 1413
Query: 231 SFIEERR---ARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKE 287
+ +R+ + L Q K + I KE +KY + N M T +L K+
Sbjct: 1414 KYNADRKKWLEEKMMLITQAKEAENIRNKE-MKKYAEDRERFFKQQNEMEILTAQLTEKD 1472
Query: 288 TSTAE-MEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEE--NLELQMEDCEERRV 344
+ + E + + A +E A+ S+V +R E +E Q+ D + +R+
Sbjct: 1473 SDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQIMDIKPKRI 1532
Query: 345 QLKALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLL 404
A +L+ E F + I SV ++ E ++ + + E+
Sbjct: 1533 S-SADPDKLQTEPLSTSFEISRNKIEDGSVVLDSCEVSTENDQSTRFPKPEL----EIQF 1587
Query: 405 TIQMGIDNLYVRLMGITLPATQR--EVVLSNTLDLNSKLAYCEGK 447
T + + + V+ G T P T + + + ++ L CE K
Sbjct: 1588 T-PLQPNKMAVKHPGCTTPVTVKIPKARKRKSNEMEEDLVKCENK 1631
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 50.4 bits (119), Expect = 4e-06
Identities = 81/400 (20%), Positives = 166/400 (41%), Gaps = 48/400 (12%)
Query: 9 VEEQTQE--LKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRR--GAQDWALAKK 64
+EE E + IT+ Q CR + + M + + ++ ++ N+R + W K
Sbjct: 777 LEEMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKL 836
Query: 65 YDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLESM 124
Y + + +A+ + E +E+L K R + ++ L++ + +
Sbjct: 837 YFKIKPLLKSAET-EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQV 895
Query: 125 QLELDSLRSQPDASKE--------ELRLLQIIRQLEN----NIEKTMIKIITSQNIHLLY 172
Q E DSL + + E ++ ++ + E+ N E T K L
Sbjct: 896 QAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELK 955
Query: 173 LDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASF 232
D+ D L+ LA E +N V N E++ + + +T E K+ +++
Sbjct: 956 KDI-DDLELTLAKVEKEKHATENKVKNLTEEMAGL---DETIAKLTKE-KKALQEAHQQT 1010
Query: 233 IEERRARENRLNQ----QKKLIDKIHTKETS-EKYRRGQMDLDFPSNLMSTETLKLRRKE 287
+++ +A E+++N + KL ++ E S E+ ++ +MDL+ + + LKL ++
Sbjct: 1011 LDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGD-LKLAQES 1069
Query: 288 TSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLK 347
T E + Q + EK+K + L+ ++ED + +QL+
Sbjct: 1070 TMDIENDKQQ----LDEKLKK----------------KEFEMSGLQSKIEDEQALGMQLQ 1109
Query: 348 ALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEE 387
+K+L+ L+ + S EK+ +D+ +E EE
Sbjct: 1110 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
Score = 37.7 bits (86), Expect = 0.026
Identities = 107/524 (20%), Positives = 206/524 (39%), Gaps = 93/524 (17%)
Query: 6 ETDVE-EQTQELKTITQLQEQCRALQIQGVKENMDQ-NKATLALLRSNIRRGAQDWALAK 63
E ++E E+ K Q + R +++ + E +++ AT A + N +R A+ + +
Sbjct: 1123 EEEIEAERASRAKAEKQRSDLSR--ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRR 1180
Query: 64 KYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLES 123
++ T+ E LRK D V I ++R QKLE
Sbjct: 1181 DLEEATLQH-----------------EATAATLRKKHADSVAELGEQIDNLQRVKQKLEK 1223
Query: 124 ----MQLELDSLRSQPDA-SKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDY 178
M++E+D L S + SK + L ++ R LE+ + + K Q +
Sbjct: 1224 EKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRAR 1283
Query: 179 LKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRA 238
L+T Y +LD+ LV +S+ T +++ RQ E I+ + A
Sbjct: 1284 LQTESGEYSRQLDEKDTLVSQ----------LSRGKQAFTQQIEELKRQLEEE-IKAKSA 1332
Query: 239 RENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRK-ETSTAEM--EY 295
+ L + D + +E E+ + + +L + ++E + R K ET + E
Sbjct: 1333 LAHALQSSRHDCDLL--REQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEEL 1390
Query: 296 QSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMED----------------- 338
+ + ++++ A HV + ++ + T++ L+ ++ED
Sbjct: 1391 EEAKKKLAQRLQDAEE--HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDK 1448
Query: 339 ---------------CEERRVQLKALVKQ-LELEEAVLKFRQKPSSISFKSVEKKMTDML 382
CEE +L+A K+ L + K + +S+++ T L
Sbjct: 1449 KQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYE----ESLDQLET--L 1502
Query: 383 KEEEERLQLAHSNMTKGQELLLTIQMGIDNLYVRLMGITLPATQREVVLSNTL-DLNSKL 441
K E + LQ S++T+ I G ++ L I Q + L L + + L
Sbjct: 1503 KRENKNLQQEISDLTE------QIAEGGKRIH-ELEKIKKQVEQEKSELQAALEEAEASL 1555
Query: 442 AYCEGKLTYLADRVQMVSRTEEGDTKVRDTLESSTLMEKYNTRI 485
+ EGK+ L ++++ E D K+ + E M++ + RI
Sbjct: 1556 EHEEGKI--LRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRI 1597
Score = 35.8 bits (81), Expect = 0.10
Identities = 80/420 (19%), Positives = 183/420 (43%), Gaps = 61/420 (14%)
Query: 6 ETDVEEQTQELKTITQLQEQC-----RALQIQGVKENMDQNKATLALLRSNIRRGAQDWA 60
ET E + I+ L EQ R +++ +K+ ++Q K S ++ ++
Sbjct: 1500 ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEK-------SELQAALEEAE 1552
Query: 61 LAKKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRK-YVFDRVNMHNLLIHLVRRRGQ 119
+ ++++ GK L ++L + EV R+ K D++ +++ I
Sbjct: 1553 ASLEHEE-------GKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRI-------- 1597
Query: 120 KLESMQLELDS-LRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDY 178
+ESMQ LD+ +RS+ DA +++ +++E ++ + I++ + + L
Sbjct: 1598 -VESMQSTLDAEIRSRNDA-------IRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRN 1649
Query: 179 LKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRA 238
+ +L + LD + +L+ ++ + +E++ + Q E S R+
Sbjct: 1650 TQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS----RKI 1705
Query: 239 RENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSG 298
E L + + +HT+ TS + +++ D E + +E AE + +
Sbjct: 1706 AEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII---QEARNAEEKAKKA 1762
Query: 299 VT---AVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEE-------RRVQ-LK 347
+T + E++K S + + L Q T ++L+ ++++ E+ +++Q L+
Sbjct: 1763 ITDAAMMAEELKKEQDTSAHLERMKKNLEQ--TVKDLQHRLDEAEQLALKGGKKQIQKLE 1820
Query: 348 ALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQ 407
A V++LE E + R + + E+K+ ++ + EE N+ + Q+L+ +Q
Sbjct: 1821 ARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEE----DRKNILRLQDLVDKLQ 1876
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 49.7 bits (117), Expect = 7e-06
Identities = 99/474 (20%), Positives = 197/474 (41%), Gaps = 71/474 (14%)
Query: 119 QKLESMQLELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHL---LYLDL 175
+++ S E+D L+ Q DA + LR + + + N+E + TS+ + + L
Sbjct: 769 EEVSSHDQEMDKLKEQYDAELQALR--ESVEEATKNVEVLASRSNTSEQDQAGTEMRVKL 826
Query: 176 LDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASF--- 232
L L G EL++ V ++ D+K A + + +RQ E +
Sbjct: 827 LQEENEKLQGRSEELERR---VAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHA 883
Query: 233 -------IEERRARENRL-----------NQQKKLIDKI-HTKETSEKYRRGQMDLDFPS 273
+ RRA EN L +QK+L +K+ E E+ RR + +++
Sbjct: 884 RKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENER 943
Query: 274 NLMSTETLKLRRK--------ETSTAEM-----EYQSGVTAVVEKVKSAVRCSHVWDITS 320
+ KL+++ TST E+ EY+ + +++ ++ + S
Sbjct: 944 WHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKS 1003
Query: 321 RFLAQRNTEENLELQMEDCEERRVQLKALVKQLELEEAVLKFRQKPSSIS---------F 371
R A + +E ++ E + +R Q +AL K+ LE+ + + + S
Sbjct: 1004 RLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLV 1063
Query: 372 KSVEKKMTDM---LKEEEERLQLAHSNMTKGQELLLTIQMGIDNLYVRLMGITLPATQRE 428
K +E K++ + L+EE L +++ +E + Q+ + L R L +
Sbjct: 1064 KQMEDKVSQLEMELEEERNNSDLLSERISRSREQM--EQLRNELLQERAARQDLECDKIS 1121
Query: 429 VVLSNTLDLNSKLAYCEGKLTYLADRVQMVSRTEEGDTKVRDTLESSTLMEKYNTRISFE 488
+ N DL S++ + EG +Y + + +V + E ++ D LES ++ N ++S
Sbjct: 1122 LERQNK-DLKSRIIHLEG--SYRSSKEGLVVQMEARIAELEDRLESEE-RDRANLQLSNR 1177
Query: 489 NREEDMIDTFQFPDMDHSYVPSRAE--------IKRQAQRLIE--GKLKAAKKK 532
E + + D +H + + + +KRQ + E +L+++KKK
Sbjct: 1178 RLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKK 1231
Score = 42.4 bits (98), Expect = 0.001
Identities = 65/315 (20%), Positives = 126/315 (40%), Gaps = 40/315 (12%)
Query: 85 CRSTMEVV-----REKLRKYVFDRVNMHNLLIHLVRRRGQKLESMQLELDSLRSQPDASK 139
C ST EV + KL V + L + + ++ E M+ L+ LRSQ +
Sbjct: 603 CNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKV 662
Query: 140 EELRLLQI-IRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTVLAGYPIELDKLQNLVV 198
EE LQ + + E + K + ++ + +++++ Q+
Sbjct: 663 EENSTLQQRLEESEGELRKNLEEL-----------------------FQVKMEREQHQ-- 697
Query: 199 NYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEE----RRARENRLNQQKKLIDKIH 254
+E+ D++ + D KR+ + + + IEE ++ ++ L +++ D +
Sbjct: 698 ---TEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLR 754
Query: 255 TKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSGVTAVVEKVKSAVRCSH 314
+E +G + + S+ + LK + A E T VE + S S
Sbjct: 755 KRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSE 814
Query: 315 VWDITSRFLAQRNTEENLELQ--MEDCEERRVQLKALVKQLELEEAVLKFRQKPSSISFK 372
+ + EEN +LQ E+ E R QL+ ++ L+ +EA K K +
Sbjct: 815 QDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIR 874
Query: 373 SVEKKMTDMLKEEEE 387
+E+ + KEE+E
Sbjct: 875 QLEEALVHARKEEKE 889
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 49.3 bits (116), Expect = 9e-06
Identities = 114/556 (20%), Positives = 230/556 (41%), Gaps = 94/556 (16%)
Query: 2 RRHSETDVEEQTQELKTITQ-LQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWA 60
+ +SE +V++ +E++ I +EQ LQ Q + D+ K T+ L++ I +Q +
Sbjct: 173 QNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQ-LDATTDEKKETVTQLQNIIEANSQHY- 230
Query: 61 LAKKYDQWTISKACGKNLPLRLAHCRSTMEV---VREKLRKYVFDRVNMHNLLIHLVRRR 117
Q I+ + L L+ H E+ + +++ + ++ L +LV++
Sbjct: 231 ------QKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQC 284
Query: 118 GQKLESMQ----LELDSLRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYL 173
+++Q EL++LR + ++ ++ I+ Q E T ++ + ++ +
Sbjct: 285 EASEKNIQKKYECELENLRKATSNANQDNQICSILLQ-----ENTFVEQVVNEKVK---- 335
Query: 174 DLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKI-MSQDAMMITDEVKRNMRQREASF 232
L D LK EL+ +++ + + ++++K+ + DA I DE F
Sbjct: 336 HLEDTLK--------ELESQHSILKDEVTYMNNLKLKLEMDAQHIKDE-----------F 376
Query: 233 IEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAE 292
ER E ++N+ L+ K EK + L N T++ +E + +
Sbjct: 377 FHEREDLEFKINEL--LLAKEEQGCVIEKLKSELAGL----NKQFCYTVEQHNREVQSLK 430
Query: 293 MEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTE--ENLELQMEDCEERRVQLKALV 350
++Q ++ + E S S +T F Q E ENL+ + ++ L+ ++
Sbjct: 431 EQHQKEISELNETFLSD---SEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIM 487
Query: 351 K--QLELEEAVLKFRQKPSSISFKS------VEKKMT------DMLKEEEERLQLAHSNM 396
+ Q EL E+ K Q+ S+ + +++K+ D L E RLQ + +
Sbjct: 488 EILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKL 547
Query: 397 TKGQELLLTIQMGIDNLYVRLMGITLPATQREVVLSNTLDLNSKLAYCEGKLTYLADRVQ 456
QEL+ ++ I NL + L +QR+ +L EGK+
Sbjct: 548 LSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKE----------LEGKIN------- 590
Query: 457 MVSRTEEGDTKVRDTLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKR 516
S TEE D + S M+ ++ + REE +I + + +E+++
Sbjct: 591 --SLTEEKDDFINKLKNSHEEMDNFHKKC---EREERLI--LELGKKVEQTIQYNSELEQ 643
Query: 517 QAQRLIEGKLKAAKKK 532
+ L G + K+K
Sbjct: 644 KVNELTGGLEETLKEK 659
Score = 31.6 bits (70), Expect = 1.9
Identities = 92/499 (18%), Positives = 201/499 (40%), Gaps = 65/499 (13%)
Query: 87 STMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLESMQLELDSLRSQPDASKEELRLLQ 146
+ ++ V E L K ++ N L +R +K+ ++ E+ L+ + EEL+ L
Sbjct: 781 NVLQAVGESLAKINEEKCN-------LAFQRDEKVLELEKEIKCLQEESVVQCEELKSLL 833
Query: 147 IIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSD 206
+ E + + ++ I S+ L DLL+ +K +E L V S
Sbjct: 834 RDYEQEKVLLRKELEEIQSEK-EALQSDLLE-MKNANEKTRLENQNLLIQVEEVSQTCSK 891
Query: 207 MKIMSQDAMMITDE--------VKRNMRQREASFI-------EERRARENRLNQQKKLID 251
+I ++ E ++ +R R A I + + + L+ K+L +
Sbjct: 892 SEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEE 951
Query: 252 KIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQS----------GVTA 301
KI E K + +++ + + + L RKET T + E +S +
Sbjct: 952 KIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRD 1011
Query: 302 VVEKVKSAVRCSHVWDITSRFL-AQRNTEENLELQMED-----------CE---ERRVQL 346
+++ +S ++ S L ++ N E ++ED CE L
Sbjct: 1012 LIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDL 1071
Query: 347 KALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTI 406
A ++ L+ +L+ + + V+K++ ++E++++ + + + +EL + +
Sbjct: 1072 LARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQL 1131
Query: 407 QMGIDNLYVRLMGITL-PATQREVVLSN---------TLDLNSKLAYCEGKLTYLADRVQ 456
Q L + + L ++ L N +LN KL K+ L ++
Sbjct: 1132 QKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIK 1191
Query: 457 MVSRTEEGDTKVRDTLESSTLM-EKYNTRIS--FENREEDMIDTFQFPDMDHSYVPS--R 511
+ + +E + +L+SS E+ NT+I ++++ D+ Q + DH + + +
Sbjct: 1192 IQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQ-AETDHLILQASLK 1250
Query: 512 AEIKRQAQRLIEGKLKAAK 530
E++ Q++ K++ A+
Sbjct: 1251 GELEASQQQVEVYKIQLAE 1269
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 49.3 bits (116), Expect = 9e-06
Identities = 80/379 (21%), Positives = 164/379 (43%), Gaps = 70/379 (18%)
Query: 34 VKENMDQNKATLALLRSNIRRGAQDWALAKKYDQWTISKACGKNLPLRL--AHCRSTMEV 91
VKE + NK+ L NI A + Q I K + P +L H R T++
Sbjct: 385 VKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQ 444
Query: 92 VREKLRKYVFDRVNMHNLLIHLVRRRGQKLESMQLELDSLRSQPDASKEELRLLQIIRQL 151
E+ VNM L ++ ++LE + + K+E+ +QL
Sbjct: 445 ENEEK-----TNVNM------LYKKNREELERKEKQY----------KKEVE----AKQL 479
Query: 152 ENNIEKTMIKIITSQNIHLLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMS 211
E ++ +K T++N D ++ ++++ L+ C +D+ I+
Sbjct: 480 EPTVQSLEMKSKTARNTP--NWDFHNH------------EEMKGLMDENCILKADIAILR 525
Query: 212 QDAMMITDE--VKRNMRQREASFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDL 269
Q+ + ++ K N ++ ++E A L + KL +++ T ET+ +Y++ DL
Sbjct: 526 QEICTMKNDNLEKENKYLKDIKIVKETNA---ALEKYIKLNEEMIT-ETAFRYQQELNDL 581
Query: 270 DFPSNLMSTETLKLRR-KETSTAEME-YQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRN 327
+ ++ E LK + K+ A++E YQS + A + K +V+
Sbjct: 582 KAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVK---------------- 625
Query: 328 TEENLELQMEDCEERRVQ--LKALVKQLELEEAVLKFRQKPSSISFKSVE---KKMTDML 382
TE NL+L +E + VQ + + + +++ E L + + I F +++ +K D L
Sbjct: 626 TERNLKLALERTRDVSVQVEMSSAISKVKAENEFLTEQLSETQIKFNALKDKFRKTRDSL 685
Query: 383 KEEEERLQLAHSNMTKGQE 401
+++ L+ +++++ Q+
Sbjct: 686 RKKSLALETVQNDLSQTQQ 704
>gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isoform
1 [Homo sapiens]
Length = 862
Score = 48.9 bits (115), Expect = 1e-05
Identities = 65/330 (19%), Positives = 141/330 (42%), Gaps = 41/330 (12%)
Query: 108 NLLIHLVRRRGQKL-------ESMQLELDSLRSQPDASKEELRLLQI-IRQLENNIEKTM 159
NLL V G KL + + +L ++ Q ++++++ LQ+ +RQ + +EKTM
Sbjct: 516 NLLQKEVHNAGNKLGRRCDMCSNYEKQLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTM 575
Query: 160 IKIITSQNIHLLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITD 219
+L D++K ++ L +I+ ++
Sbjct: 576 KD----------KQELEDFIKQSSEDSSHQISAL-------VLRAQASEILLEELQQGLS 618
Query: 220 EVKRNMRQREASFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTE 279
+ KR+++++ A ++ R L + +K D + K + + D P +
Sbjct: 619 QAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQQAEDFILPDTTEALR 678
Query: 280 TLKLRRKETSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDC 339
L L+ +E + ++ V EK+K+ + I + + N EE L+L++E+C
Sbjct: 679 ELVLKYREDI---INVRTAADHVEEKLKAEILFLKE-QIQAEQCLKENLEETLQLEIENC 734
Query: 340 EERRV---QLKALVKQLELEEAVLK--FRQKPSSI-SFKSVEKKMTDMLKEEE------E 387
+E LKA ++++++E+ L+ R+K + S + ++ + + LK+E E
Sbjct: 735 KEEIASISSLKAELERIKVEKGQLESTLREKSQQLESLQEIKISLEEQLKKETAAKATVE 794
Query: 388 RLQLAHSNMTKGQELLLTIQMGIDNLYVRL 417
+L N + + L + + +V+L
Sbjct: 795 QLMFEEKNKAQRLQTELDVSEQVQRDFVKL 824
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 48.5 bits (114), Expect = 2e-05
Identities = 81/400 (20%), Positives = 165/400 (41%), Gaps = 48/400 (12%)
Query: 9 VEEQTQE--LKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRR--GAQDWALAKK 64
+EE E + IT+ Q CR ++ M + + ++ ++ NIR + W K
Sbjct: 777 LEEMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKL 836
Query: 65 YDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLESM 124
Y + + +A+ + E +E+L K R + ++ L++ + +
Sbjct: 837 YFKIKPLLKSAET-EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQV 895
Query: 125 QLELDSLRSQPDASKE--------ELRLLQIIRQLEN----NIEKTMIKIITSQNIHLLY 172
Q E D+L + + E ++ ++ + E+ N E T K L
Sbjct: 896 QAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELK 955
Query: 173 LDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASF 232
D+ D L+ LA E +N V N E++ + + +T E K+ +++
Sbjct: 956 KDI-DDLELTLAKVEKEKHATENKVKNLTEEMAGL---DETIAKLTKE-KKALQEAHQQT 1010
Query: 233 IEERRARENRLNQ----QKKLIDKIHTKETS-EKYRRGQMDLDFPSNLMSTETLKLRRKE 287
+++ + E+++N + KL ++ E S E+ ++ MDL+ + + LKL ++
Sbjct: 1011 LDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGD-LKLAQES 1069
Query: 288 TSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLK 347
T E + Q + EK+K + NL+ ++ED + +QL+
Sbjct: 1070 TMDTENDKQQ----LNEKLKK----------------KEFEMSNLQGKIEDEQALAIQLQ 1109
Query: 348 ALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEE 387
+K+L+ L+ + S EK+ +D+ +E EE
Sbjct: 1110 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 48.1 bits (113), Expect = 2e-05
Identities = 108/541 (19%), Positives = 217/541 (40%), Gaps = 70/541 (12%)
Query: 3 RHSETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWALA 62
R +E D+ E T EL + QL++ + + +K+ +D+ TL L+ + R Q
Sbjct: 1376 RKAEQDMRELTYELNAL-QLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQ---AE 1431
Query: 63 KKYDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRGQKLE 122
K Y Q + G+ L M+ + L+K + N L L +G+
Sbjct: 1432 KGYSQQL--RELGRQLNQTTGKAEEAMQEASD-LKKI---KRNYQLELESLNHEKGK--- 1482
Query: 123 SMQLELDSL-RSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNIHLL------YLDL 175
+Q E+D + R+ A K L I + E ++I ++ HL + L
Sbjct: 1483 -LQREVDRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQL 1541
Query: 176 LDYLKTVLAGYPIELDKLQNL-----VVNYCSELSDMKIMSQDAMMITDEVKRNMRQREA 230
L +K DK+Q L N C+E+ K+ ++ +E K M++ +A
Sbjct: 1542 LQNIKAEKENN----DKIQRLNEELEKSNECAEMLKQKV--EELTRQNNETKLMMQRIQA 1595
Query: 231 ---SFIEERRARENRLNQQKKLID--KIHTKETSEK-YRRGQMDLDFPSNLMSTETLKLR 284
+ + E++ + R K D K + T+E +++ + + DF + E L
Sbjct: 1596 ESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEE-DLA 1654
Query: 285 RKETSTAEMEYQSGV-TAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERR 343
+ + +E + + +++ K VR N EL E+RR
Sbjct: 1655 KSQNLVSEFKQKCDQQNIIIQNTKKEVR-----------------NLNAELNASKEEKRR 1697
Query: 344 VQLKALVKQLELEEAVLKFRQKPSSISFKSVEKKMTD----MLKEEEERLQLAHSNMTKG 399
+ K ++Q +++E + ++ + K++E++MT + +EE + + + K
Sbjct: 1698 GEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKK 1757
Query: 400 QELLLTIQMGIDN--LYVRLMGITLPATQREVVLSNTLDLNSKLAYCEGKLTYLADRVQM 457
E L+ ++ +N +RL ++L + N + + E +L +++Q
Sbjct: 1758 MEKLMESKVITENDISGIRLDFVSL-QQENSRAQENAKLCETNIKELERQLQQYREQMQQ 1816
Query: 458 VSRTEEGDTKVRDTLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQ 517
E + LE + +K EN ++ M Q + +H V + EI+++
Sbjct: 1817 GQHMEANHYQKCQKLEDELIAQKREV----ENLKQKMDQ--QIKEHEHQLVLLQCEIQKK 1870
Query: 518 A 518
+
Sbjct: 1871 S 1871
Score = 43.1 bits (100), Expect = 6e-04
Identities = 58/250 (23%), Positives = 113/250 (45%), Gaps = 47/250 (18%)
Query: 155 IEKTMIKIITSQNIHLLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDA 214
+E+ IK + H Y DLL K + +E KL + SEL M
Sbjct: 1102 LEEEEIKRCKETSEHGAYSDLLQRQKATV----LENSKLTGKI----SELERM------- 1146
Query: 215 MMITDEVKRNMRQREASFIEERRARENRLNQQKKLID-----KIHTKETSEKYRRGQMDL 269
E+K+ + E + R A EN L +Q++ ++ KI + +++YRR
Sbjct: 1147 ---VAELKKQKSRVEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRR----- 1198
Query: 270 DFPSNLMSTETLKLRRKETSTAEMEYQSGVTAVVEKVKSAVR---CSHVWDITSRFLAQR 326
ET+ +R KE + E+E +T E ++AV + + +R
Sbjct: 1199 -------ELETI-VREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRR 1250
Query: 327 NTEENL---ELQMEDCEERRVQL-KALVKQLELEEAVLK-FRQKPSSISFKSVEKKMTDM 381
E++L +L + D E+++ +L + L ++ + EE +LK +Q ++F +K++ +
Sbjct: 1251 TLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAF---QKQVAEK 1307
Query: 382 LKEEEERLQL 391
+E+++++L
Sbjct: 1308 QLKEKQKIEL 1317
Score = 33.9 bits (76), Expect = 0.38
Identities = 57/264 (21%), Positives = 116/264 (43%), Gaps = 55/264 (20%)
Query: 273 SNLMSTETLKLRRKETSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENL 332
S + S + KE + + YQ E +KSA R + + ++++ N+
Sbjct: 700 SQVFSGSDITQLEKEVNVCKQYYQ-------ELLKSAEREEQEESVYNLYISE---VRNI 749
Query: 333 ELQMEDCEERRV-QLKALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQL 391
L++E+CE+R + Q++ +++ +L E+V + ++ + LK+E ERL
Sbjct: 750 RLRLENCEDRLIRQIRTPLERDDLHESVFRITEQ--------------EKLKKELERL-- 793
Query: 392 AHSNMTKGQELLLTIQMGIDNLYVRLMGITLPATQR---EVVLSNTLDLNSKLAYCEGKL 448
++ L TI + + + + T R VVL N + S +
Sbjct: 794 --------KDDLGTITNKCEEFFSQAAASSSVPTLRSELNVVLQNMNQVYSMSS------ 839
Query: 449 TYLADRVQMVSRTEEGDTKVRDTLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYV 508
TY+ D+++ V+ +++T + L++ Y T++ E E + D ++ +
Sbjct: 840 TYI-DKLKTVNLV------LKNTQAAEALVKLYETKLCEE--EAVIADKNNIENLISTLK 890
Query: 509 PSRAEI--KRQAQRLIEGKLKAAK 530
R+E+ KRQ +E +L+ AK
Sbjct: 891 QWRSEVDEKRQVFHALEDELQKAK 914
Score = 33.5 bits (75), Expect = 0.50
Identities = 66/363 (18%), Positives = 149/363 (41%), Gaps = 57/363 (15%)
Query: 5 SETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWALAKK 64
+E + ++ Q L + +C + Q V+E QN T L+ I+ +++ L K+
Sbjct: 1547 AEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNET-KLMMQRIQAESENIVLEKQ 1605
Query: 65 YDQWTISKACGKNLPLRLAHCRSTMEVVREKLRKYVF--------------DRVNMHNLL 110
TI + C + L ++ + + E L K D NL+
Sbjct: 1606 ----TIQQRC-EALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLV 1660
Query: 111 IHLVRRRGQK---LESMQLELDSLRSQPDASKEELRL----LQI----IRQLENNIEKTM 159
++ Q+ +++ + E+ +L ++ +ASKEE R +Q+ +++L N ++K
Sbjct: 1661 SEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQ 1720
Query: 160 ----IKIITSQNIH---LLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKI--- 209
+K I Q H +L+ + K + +++KL V +++S +++
Sbjct: 1721 DELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFV 1780
Query: 210 -------MSQDAMMITD----EVKRNMRQREASFIEERRARENRLNQQKKLIDKIHTKET 258
+Q+ + + E++R ++Q + + N + +KL D++ ++
Sbjct: 1781 SLQQENSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKR 1840
Query: 259 SEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEMEYQSGVTAVVEKVKSAVRCSHVWDI 318
+ + +MD + L+ ++ STA+ T + + C H ++
Sbjct: 1841 EVENLKQKMDQQIKEHEHQLVLLQCEIQKKSTAK-----DCTFKPDFEMTVKECQHSGEL 1895
Query: 319 TSR 321
+SR
Sbjct: 1896 SSR 1898
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 48.1 bits (113), Expect = 2e-05
Identities = 80/379 (21%), Positives = 164/379 (43%), Gaps = 70/379 (18%)
Query: 34 VKENMDQNKATLALLRSNIRRGAQDWALAKKYDQWTISKACGKNLPLRL--AHCRSTMEV 91
VKE + NK+ L NI A + Q I K + P +L H R T++
Sbjct: 385 VKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQ 444
Query: 92 VREKLRKYVFDRVNMHNLLIHLVRRRGQKLESMQLELDSLRSQPDASKEELRLLQIIRQL 151
E+ VNM L ++ ++LE + + K+E+ +QL
Sbjct: 445 ENEEK-----TNVNM------LYKKNREELERKEKQY----------KKEVE----AKQL 479
Query: 152 ENNIEKTMIKIITSQNIHLLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMS 211
E ++ +K T++N D ++ ++++ L+ C +D+ I+
Sbjct: 480 EPTVQSLEMKSKTARNTP--NRDFHNH------------EEMKGLMDENCILKADIAILR 525
Query: 212 QDAMMITDE--VKRNMRQREASFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDL 269
Q+ + ++ K N ++ ++E A L + KL +++ T ET+ +Y++ DL
Sbjct: 526 QEICTMKNDNLEKENKYLKDIKIVKETNA---ALEKYIKLNEEMIT-ETAFRYQQELNDL 581
Query: 270 DFPSNLMSTETLKLRR-KETSTAEME-YQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRN 327
+ ++ E LK + K+ A++E YQS + A + K +V+
Sbjct: 582 KAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVK---------------- 625
Query: 328 TEENLELQMEDCEERRVQ--LKALVKQLELEEAVLKFRQKPSSISFKSVE---KKMTDML 382
TE NL+L +E + VQ + + + +++ E L + + I F +++ +K D L
Sbjct: 626 TERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSL 685
Query: 383 KEEEERLQLAHSNMTKGQE 401
+++ L+ +++++ Q+
Sbjct: 686 RKKSLALETVQNDLSQTQQ 704
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 48.1 bits (113), Expect = 2e-05
Identities = 81/406 (19%), Positives = 162/406 (39%), Gaps = 60/406 (14%)
Query: 9 VEEQTQE--LKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWALAKKYD 66
+EE E + IT+ Q CR ++ + M Q + L ++ N+R
Sbjct: 776 LEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRA-------FMNVK 828
Query: 67 QWTISKACGKNLPL--------RLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLVRRRG 118
W K K PL +A + + +++L K R + ++ L++ +
Sbjct: 829 HWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKN 888
Query: 119 QKLESMQLELDSLRSQPDASKE--------ELRLLQIIRQLEN----NIEKTMIKIITSQ 166
+Q E DSL + ++ E ++ ++ + E N E T K
Sbjct: 889 DLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLED 948
Query: 167 NIHLLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVKRNMR 226
L D+ D L+ LA E +N V N E++ + + + + K+ ++
Sbjct: 949 ECSELKKDI-DDLELTLAKVEKEKHATENKVKNLTEEMAGL----DETIAKLSKEKKALQ 1003
Query: 227 QREASFIEERRARENRLN----QQKKLIDKIHTKETS-EKYRRGQMDLDFPSNLMSTETL 281
+ +++ +A E+++N + KL ++ E S E+ ++ +MDL+ + + L
Sbjct: 1004 ETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD-L 1062
Query: 282 KLRRKETSTAEMEYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEE 341
KL ++ T E + Q + +EK + + NL ++ED +
Sbjct: 1063 KLAQESTMDMENDKQQ-LDEKLEKKEFEI-------------------SNLISKIEDEQA 1102
Query: 342 RRVQLKALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEE 387
+QL+ +K+L+ L + S EK+ +D+ +E EE
Sbjct: 1103 VEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEE 1148
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 47.8 bits (112), Expect = 3e-05
Identities = 72/322 (22%), Positives = 143/322 (44%), Gaps = 34/322 (10%)
Query: 116 RRGQKLESMQLELDSLRSQPDASKEELR-LLQIIRQLENNIEKTMIKIITSQNIHLLYLD 174
RR Q ++MQ EL+ L+++ DASKEE++ +LQ + +L N ++ ++ + L D
Sbjct: 464 RRDQ--DNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSD 521
Query: 175 LLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKI-MSQDAMMITDEVKRN-MRQREASF 232
L+ LA EL KL+ + + ++M + +D I V N ++Q E +
Sbjct: 522 ELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTG 581
Query: 233 IEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAE 292
+ + RL I K+ ++ + R Q++ ST+T ++ E + E
Sbjct: 582 MIDEEFTVARL-----YISKMKSEVKTMVKRCKQLE--------STQTESNKKMEENEKE 628
Query: 293 M-EYQSGVTAVVEKVKSAVRCSHVWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVK 351
+ Q ++ K+KS +T + LE ++ E VQL+A K
Sbjct: 629 LAACQLRISQHEAKIKS---------LTEYLQNVEQKKRQLEESVDALSEELVQLRAQEK 679
Query: 352 QLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQ---- 407
E+E+ L Q + + ++VE+++ + ++++ + +L+ +Q
Sbjct: 680 VHEMEKEHLNKVQTANEVK-QAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQ 738
Query: 408 -MGIDNLYVRLMGITLPATQRE 428
M ++ +R+ L AT +E
Sbjct: 739 KMMLEQERLRVEHEKLKATDQE 760
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 47.4 bits (111), Expect = 3e-05
Identities = 96/488 (19%), Positives = 197/488 (40%), Gaps = 59/488 (12%)
Query: 88 TMEVVREKLRKYVF-----DRVNM----HNLLIHLVRRRGQKLESMQLELDSLRSQPDAS 138
T E++ EK R V DR+ HN+ + + Q+ + MQ++ +R Q +A
Sbjct: 359 TQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEA- 417
Query: 139 KEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTV--LAGYPIELDKLQNL 196
E L Q L + + T ++ + Q+ L L DY + V L +L + +
Sbjct: 418 -EIAHLKQENGILRDAVSNTTNQLESKQSAELNKL-RQDYARLVNELTEKTGKLQQEEVQ 475
Query: 197 VVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARENRLNQQKKLIDKIHTK 256
N + +K+ Q+A +EV+ +R+R A ++ +++ ++ + +H+K
Sbjct: 476 KKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSK 535
Query: 257 ETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAE----MEYQSGVTAVVEKVKSAVRC 312
T + Q++ LM +E ++ ++E+ + +E + A +++ S +
Sbjct: 536 LTDTLVSKQQLEQRL-MQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAA 594
Query: 313 SHVWDITSRFLAQ---------RNTEENL----------ELQMEDCEERRVQLKALVKQL 353
+ + L + + TE++L E +++D + LKA V++L
Sbjct: 595 QTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKL 654
Query: 354 ELEEAVLKFRQKPSSISFKSVEKKM---TDMLKEEEERLQLAHSNMTKGQELLLTIQMGI 410
+ L Q ++ + +++ + D ++ EE+LQ SN + ++L +
Sbjct: 655 Q----ALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKAL 710
Query: 411 DNLYVRLMGITLPATQREVVLSNTLDLNSKLAYCEGKLTYLADRVQMVSRTEEGDTKVRD 470
+ +L + ++VV + K + L + V+ EE +R
Sbjct: 711 KSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRT 770
Query: 471 -----TLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIEGK 525
T E L K N ++SF + E++ D +IK + L
Sbjct: 771 ENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKD---------GKIKSVEELLEAEL 821
Query: 526 LKAAKKKK 533
LK A K+K
Sbjct: 822 LKVANKEK 829
Score = 43.9 bits (102), Expect = 4e-04
Identities = 70/413 (16%), Positives = 182/413 (44%), Gaps = 56/413 (13%)
Query: 17 KTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWALAKKYDQWTISK--AC 74
+ + +L E+ LQ + V++ + AT L+ ++ + W + Y + ++ A
Sbjct: 457 RLVNELTEKTGKLQQEEVQKKNAEQAATQ--LKVQLQEAERRWEEVQSYIRKRTAEHEAA 514
Query: 75 GKNLPLRLAHCRSTMEVVREKLRKYVFDRVNMHNLLIHLV---RRRGQKLESMQLELDSL 131
++L + + ++ + KL + + + L+ L+ ++R K ES+Q+++ +
Sbjct: 515 QQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDI 574
Query: 132 RSQPDASKEELR------------------LLQIIRQLENNIEKTMIKI------ITSQN 167
Q +A K +++ L ++I + + I++T + +TS+
Sbjct: 575 LEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKE 634
Query: 168 IHLLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAMMITDEVK---RN 224
L + +++L E+ KLQ L + +++ M Q + D+++
Sbjct: 635 EELKDIQNMNFLLKA------EVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQ 688
Query: 225 MRQREASFIEERRARENRLNQQKKLIDKIHTKETSEKYRRGQMDLDFPSNLMSTETLKLR 284
++ ++ +EE + ++ K + K+ T SE+ + ++ + ++ +
Sbjct: 689 LQHEISNKMEEFKILNDQNKALKSEVQKLQTL-VSEQPNKDVVE-------QMEKCIQEK 740
Query: 285 RKETSTAEMEYQSGVTAVVEKVK--SAVRCSH------VWDITSRFLAQRNTEENLELQM 336
++ T E ++G+ V K + +A+R + V D+ ++ Q + +E
Sbjct: 741 DEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELK 800
Query: 337 EDCEERRVQLKALVKQLELEEAVLKFRQKPSSISFKSVEKKMTDMLKEEEERL 389
+ E+ ++K++ + LE E + ++K +S S +++ ++LK +EE++
Sbjct: 801 KVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQM 853
Score = 36.2 bits (82), Expect = 0.077
Identities = 89/457 (19%), Positives = 187/457 (40%), Gaps = 68/457 (14%)
Query: 9 VEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWALAKKYDQW 68
+ E+ ++K++ +L E L++ ++ + + + N+ +G K +Q
Sbjct: 803 IHEKDGKIKSVEELLE-AELLKVANKEKTVQLSITSKVQELQNLLKG--------KEEQM 853
Query: 69 TISKACGKNLPLRLAHCRSTMEVVREK---LRKYVFDRVNMHNLLIHLVRRRGQKLESMQ 125
KA + LA+ ++ ++E+ L+ +V V HNL + ++LE +
Sbjct: 854 NTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHV-QEVAQHNLKEASSASQFEELEIVL 912
Query: 126 LELDS--------LRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNI--------H 169
E ++ L+ + + +LLQ ++ EN + K+ I+ + QN H
Sbjct: 913 KEKENELKRLEAMLKERESDLSSKTQLLQDVQD-ENKLFKSQIEQLKQQNYQQASSFPPH 971
Query: 170 LLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAM--------MITDEV 221
L ++ + ++G ELD L++ V + + +D++ + +AM M+ D+V
Sbjct: 972 EELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKV 1031
Query: 222 KRNMRQR----EASFIEERRARENRLNQ----------------QKKLIDKIHTKETSEK 261
+ ++R EA +E + + + +KK + + SE+
Sbjct: 1032 NKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEE 1091
Query: 262 YRRGQMDLDFPSNLMSTETLKLRRKETSTAEME-----YQSGVTAVVEKVKSAVRCSH-- 314
+ + L + + L+ + ++ AE E Q V K K V SH
Sbjct: 1092 VKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKT 1151
Query: 315 VWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLELEEAVLKFRQKPSSI-SFKS 373
+ + S F + E L + +D E R + + L ++ELE+A ++ + + K+
Sbjct: 1152 IKQMQSSFTSSEQELERLRSENKDIENLRREREHL--EMELEKAEMERSTYVTEVRELKA 1209
Query: 374 VEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQMGI 410
+ L+ E+ Q ++ K Q+ L IQ I
Sbjct: 1210 QLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1246
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 47.4 bits (111), Expect = 3e-05
Identities = 96/488 (19%), Positives = 197/488 (40%), Gaps = 59/488 (12%)
Query: 88 TMEVVREKLRKYVF-----DRVNM----HNLLIHLVRRRGQKLESMQLELDSLRSQPDAS 138
T E++ EK R V DR+ HN+ + + Q+ + MQ++ +R Q +A
Sbjct: 359 TQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEA- 417
Query: 139 KEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTV--LAGYPIELDKLQNL 196
E L Q L + + T ++ + Q+ L L DY + V L +L + +
Sbjct: 418 -EIAHLKQENGILRDAVSNTTNQLESKQSAELNKL-RQDYARLVNELTEKTGKLQQEEVQ 475
Query: 197 VVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARENRLNQQKKLIDKIHTK 256
N + +K+ Q+A +EV+ +R+R A ++ +++ ++ + +H+K
Sbjct: 476 KKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSK 535
Query: 257 ETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAE----MEYQSGVTAVVEKVKSAVRC 312
T + Q++ LM +E ++ ++E+ + +E + A +++ S +
Sbjct: 536 LTDTLVSKQQLEQRL-MQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAA 594
Query: 313 SHVWDITSRFLAQ---------RNTEENL----------ELQMEDCEERRVQLKALVKQL 353
+ + L + + TE++L E +++D + LKA V++L
Sbjct: 595 QTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKL 654
Query: 354 ELEEAVLKFRQKPSSISFKSVEKKM---TDMLKEEEERLQLAHSNMTKGQELLLTIQMGI 410
+ L Q ++ + +++ + D ++ EE+LQ SN + ++L +
Sbjct: 655 Q----ALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKAL 710
Query: 411 DNLYVRLMGITLPATQREVVLSNTLDLNSKLAYCEGKLTYLADRVQMVSRTEEGDTKVRD 470
+ +L + ++VV + K + L + V+ EE +R
Sbjct: 711 KSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRT 770
Query: 471 -----TLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIEGK 525
T E L K N ++SF + E++ D +IK + L
Sbjct: 771 ENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKD---------GKIKSVEELLEAEL 821
Query: 526 LKAAKKKK 533
LK A K+K
Sbjct: 822 LKVANKEK 829
Score = 42.4 bits (98), Expect = 0.001
Identities = 99/527 (18%), Positives = 219/527 (41%), Gaps = 74/527 (14%)
Query: 6 ETDVEEQTQELKTITQLQEQCRALQIQGVKENMDQNKATLALLRSNIRRGAQDWALAKKY 65
E ++ + + KT+ L+++ +AL+ + N+ KA + S ++ L K
Sbjct: 818 EAELLKVANKEKTVQDLKQEIKALKEE--IGNVQLEKAQQLSITSKVQELQN--LLKGKE 873
Query: 66 DQWTISKACGKNLPLRLAHCRSTMEVVREK---LRKYVFDRVNMHNLLIHLVRRRGQKLE 122
+Q KA + LA+ ++ ++E+ L+ +V V HNL + ++LE
Sbjct: 874 EQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHV-QEVAQHNLKEASSASQFEELE 932
Query: 123 SMQLELDS--------LRSQPDASKEELRLLQIIRQLENNIEKTMIKIITSQNI------ 168
+ E ++ L+ + + +LLQ ++ EN + K+ I+ + QN
Sbjct: 933 IVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQD-ENKLFKSQIEQLKQQNYQQASSF 991
Query: 169 --HLLYLDLLDYLKTVLAGYPIELDKLQNLVVNYCSELSDMKIMSQDAM--------MIT 218
H L ++ + ++G ELD L++ V + + +D++ + +AM M+
Sbjct: 992 PPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQ 1051
Query: 219 DEVKRNMRQR----EASFIEERRARENRLNQ----------------QKKLIDKIHTKET 258
D+V + ++R EA +E + + + +KK + +
Sbjct: 1052 DKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSG 1111
Query: 259 SEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAEME-----YQSGVTAVVEKVKSAVRCS 313
SE+ + + L + + L+ + ++ AE E Q V K K V S
Sbjct: 1112 SEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDES 1171
Query: 314 H--VWDITSRFLAQRNTEENLELQMEDCEERRVQLKALVKQLELEEAVLKFRQKPSSISF 371
H + + S F + E L + +D E R + + L ++ELE+A ++ ++
Sbjct: 1172 HKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHL--EMELEKAEME------RSTY 1223
Query: 372 KSVEKKMTDMLKEEEERLQLAHSNMTKGQELLLTIQMGIDNLYVRLMGITLPATQREVVL 431
+ +++ D+L E +++L ++S + E L ++ ++ +L +R+ V
Sbjct: 1224 VTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKL---RTEQNERQKVA 1280
Query: 432 SNTLDLNSKLAYCEGKLTYLADRVQMVSRTE---EGDTKVRDTLESS 475
+ L + K+ A ++ ++ E ++ ++T+ S
Sbjct: 1281 GDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVS 1327
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 47.4 bits (111), Expect = 3e-05
Identities = 96/488 (19%), Positives = 197/488 (40%), Gaps = 59/488 (12%)
Query: 88 TMEVVREKLRKYVF-----DRVNM----HNLLIHLVRRRGQKLESMQLELDSLRSQPDAS 138
T E++ EK R V DR+ HN+ + + Q+ + MQ++ +R Q +A
Sbjct: 359 TQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEA- 417
Query: 139 KEELRLLQIIRQLENNIEKTMIKIITSQNIHLLYLDLLDYLKTV--LAGYPIELDKLQNL 196
E L Q L + + T ++ + Q+ L L DY + V L +L + +
Sbjct: 418 -EIAHLKQENGILRDAVSNTTNQLESKQSAELNKL-RQDYARLVNELTEKTGKLQQEEVQ 475
Query: 197 VVNYCSELSDMKIMSQDAMMITDEVKRNMRQREASFIEERRARENRLNQQKKLIDKIHTK 256
N + +K+ Q+A +EV+ +R+R A ++ +++ ++ + +H+K
Sbjct: 476 KKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSK 535
Query: 257 ETSEKYRRGQMDLDFPSNLMSTETLKLRRKETSTAE----MEYQSGVTAVVEKVKSAVRC 312
T + Q++ LM +E ++ ++E+ + +E + A +++ S +
Sbjct: 536 LTDTLVSKQQLEQRL-MQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAA 594
Query: 313 SHVWDITSRFLAQ---------RNTEENL----------ELQMEDCEERRVQLKALVKQL 353
+ + L + + TE++L E +++D + LKA V++L
Sbjct: 595 QTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKL 654
Query: 354 ELEEAVLKFRQKPSSISFKSVEKKM---TDMLKEEEERLQLAHSNMTKGQELLLTIQMGI 410
+ L Q ++ + +++ + D ++ EE+LQ SN + ++L +
Sbjct: 655 Q----ALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKAL 710
Query: 411 DNLYVRLMGITLPATQREVVLSNTLDLNSKLAYCEGKLTYLADRVQMVSRTEEGDTKVRD 470
+ +L + ++VV + K + L + V+ EE +R
Sbjct: 711 KSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRT 770
Query: 471 -----TLESSTLMEKYNTRISFENREEDMIDTFQFPDMDHSYVPSRAEIKRQAQRLIEGK 525
T E L K N ++SF + E++ D +IK + L
Sbjct: 771 ENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKD---------GKIKSVEELLEAEL 821
Query: 526 LKAAKKKK 533
LK A K+K
Sbjct: 822 LKVANKEK 829
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.129 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,474,899
Number of Sequences: 37866
Number of extensions: 662740
Number of successful extensions: 4121
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 374
Number of HSP's that attempted gapping in prelim test: 3430
Number of HSP's gapped (non-prelim): 914
length of query: 534
length of database: 18,247,518
effective HSP length: 107
effective length of query: 427
effective length of database: 14,195,856
effective search space: 6061630512
effective search space used: 6061630512
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.