Guide to the Human Genome
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Search of human proteins with 89886468

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|89886468 fibronectin type III and SPRY domain containing
1-like isoform 1 [Homo sapiens]
         (498 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|89886468 fibronectin type III and SPRY domain containing 1-li...  1004   0.0  
gi|223718222 fibronectin type III and SPRY domain containing 1-l...   997   0.0  
gi|13236585 fibronectin type III and SPRY domain containing 1 [H...   615   e-176
gi|13994289 fibronectin type III and SPRY domain containing 1-li...   224   2e-58
gi|148833499 midline 1 [Homo sapiens]                                 217   2e-56
gi|4557753 midline 1 [Homo sapiens]                                   217   2e-56
gi|15451852 midline 1 [Homo sapiens]                                  217   2e-56
gi|223890259 midline 2 isoform 2 [Homo sapiens]                       203   3e-52
gi|223890257 midline 2 isoform 1 [Homo sapiens]                       192   5e-49
gi|47174859 tripartite motif-containing 46 [Homo sapiens]             119   5e-27
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]   115   7e-26
gi|134288906 tripartite motif-containing 67 [Homo sapiens]            109   5e-24
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]      103   3e-22
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 99   7e-21
gi|46409324 SPRY domain containing 4 [Homo sapiens]                    84   4e-16
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]        82   9e-16
gi|68160937 tripartite motif-containing 25 [Homo sapiens]              82   1e-15
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]       82   1e-15
gi|55741632 fibronectin type III and SPRY domain containing 2 [H...    80   3e-15
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]    78   2e-14
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]    78   2e-14
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]    78   2e-14
gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]           71   2e-12
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]            70   6e-12
gi|22749269 ring finger protein 129 [Homo sapiens]                     69   8e-12
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]            67   4e-11
gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ...    67   5e-11
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ...    67   5e-11
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ...    67   5e-11
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]       62   9e-10

>gi|89886468 fibronectin type III and SPRY domain containing 1-like
           isoform 1 [Homo sapiens]
          Length = 498

 Score = 1004 bits (2597), Expect = 0.0
 Identities = 498/498 (100%), Positives = 498/498 (100%)

Query: 1   MDSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE 60
           MDSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE
Sbjct: 1   MDSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE 60

Query: 61  VKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQI 120
           VKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQI
Sbjct: 61  VKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQI 120

Query: 121 KDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADN 180
           KDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADN
Sbjct: 121 KDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADN 180

Query: 181 SVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSK 240
           SVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSK
Sbjct: 181 SVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSK 240

Query: 241 YMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQES 300
           YMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQES
Sbjct: 241 YMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQES 300

Query: 301 KIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQ 360
           KIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQ
Sbjct: 301 KIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQ 360

Query: 361 KDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIG 420
           KDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIG
Sbjct: 361 KDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIG 420

Query: 421 VFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQK 480
           VFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQK
Sbjct: 421 VFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQK 480

Query: 481 SENGMTGSASSLNNVVTQ 498
           SENGMTGSASSLNNVVTQ
Sbjct: 481 SENGMTGSASSLNNVVTQ 498


>gi|223718222 fibronectin type III and SPRY domain containing 1-like
           isoform 3 [Homo sapiens]
          Length = 530

 Score =  997 bits (2578), Expect = 0.0
 Identities = 494/495 (99%), Positives = 495/495 (100%)

Query: 4   QKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 63
           Q+EALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE
Sbjct: 36  QQEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 95

Query: 64  SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 123
           SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR
Sbjct: 96  SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 155

Query: 124 VTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVT 183
           VTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVT
Sbjct: 156 VTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVT 215

Query: 184 VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN 243
           VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN
Sbjct: 216 VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN 275

Query: 244 FRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIK 303
           FRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIK
Sbjct: 276 FRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIK 335

Query: 304 GKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDC 363
           GKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDC
Sbjct: 336 GKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDC 395

Query: 364 KSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFC 423
           KSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFC
Sbjct: 396 KSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFC 455

Query: 424 DFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSEN 483
           DFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSEN
Sbjct: 456 DFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSEN 515

Query: 484 GMTGSASSLNNVVTQ 498
           GMTGSASSLNNVVTQ
Sbjct: 516 GMTGSASSLNNVVTQ 530


>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
           sapiens]
          Length = 496

 Score =  615 bits (1586), Expect = e-176
 Identities = 300/495 (60%), Positives = 388/495 (78%), Gaps = 3/495 (0%)

Query: 1   MDSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE 60
           M+ Q+EAL++II TLA KN+EIQ+FI +L   L  V+ NS+ +  +L+ EF SL+S+L+E
Sbjct: 1   MEEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEE 60

Query: 61  VKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQI 120
           +KE M+  IKQ++A ++ ELQ+Q++ C  ALE+SEELLE A ++L   + E+F +AA+QI
Sbjct: 61  LKEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQI 120

Query: 121 KDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADN 180
           KD VTMA AFRLSLK KVSDNM+HLMVDF+QERQMLQ LKFLPVP AP ID  E LVADN
Sbjct: 121 KDGVTMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVADN 180

Query: 181 SVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSK 240
            VT+ WRMP+ED+KIDH++LE+R+TNF+G PR+K+++ W +I+ I+ TEYTL+GLKFD K
Sbjct: 181 CVTLVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMK 240

Query: 241 YMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQES 300
           YMNFRV+ACNKAVAGE+S+PVTLET A  F LD S+SH NL+V+D  VEWD  GGK Q+ 
Sbjct: 241 YMNFRVKACNKAVAGEFSEPVTLETPAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDI 300

Query: 301 KIKGKENKGRSGTP--SPKR-TSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEV 357
           K + K+ KGR+ +P  SP R T    R P+ RG RDRFT ESYTVLGDT I+ G+HYWEV
Sbjct: 301 KAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEV 360

Query: 358 KAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPE 417
           + + D K++ VGVAY++LG+F+QLGKT  SWC+HVNNWLQ +F AKH NKVK LD  VP+
Sbjct: 361 RYEPDSKAFGVGVAYRSLGRFEQLGKTAASWCLHVNNWLQVSFTAKHANKVKVLDAPVPD 420

Query: 418 KIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVRT 477
            +GV CDF  G LSFY+A +KQ+L++FKT+FTQP+LP F VWCG   ++TG+QVPSAVR 
Sbjct: 421 CLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAVRC 480

Query: 478 LQKSENGMTGSASSL 492
           LQK  +  + S +SL
Sbjct: 481 LQKRGSATSSSNTSL 495


>gi|13994289 fibronectin type III and SPRY domain containing 1-like
           isoform 2 [Homo sapiens]
          Length = 145

 Score =  224 bits (570), Expect = 2e-58
 Identities = 115/115 (100%), Positives = 115/115 (100%)

Query: 1   MDSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE 60
           MDSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE
Sbjct: 1   MDSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE 60

Query: 61  VKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSK 115
           VKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSK
Sbjct: 61  VKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSK 115


>gi|148833499 midline 1 [Homo sapiens]
          Length = 667

 Score =  217 bits (553), Expect = 2e-56
 Identities = 150/483 (31%), Positives = 245/483 (50%), Gaps = 54/483 (11%)

Query: 2   DSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEV 61
           D  K+ L+  ++ L  +N E++  +  L  T + V+ N+S   ++L EE D L  I+ + 
Sbjct: 217 DKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQR 276

Query: 62  KESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIK 121
           ++ +   IK+ +  + ++L  QI+ C   +E S  L+  A  SL   +   F + A+ I 
Sbjct: 277 RQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNIT 336

Query: 122 DRVTMASAFRLSLKPKV--SDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVAD 179
           +RV+MA+A    L P++  +D      +DFS+E+++L+ L +L  P  P I    C  + 
Sbjct: 337 ERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASY 396

Query: 180 NSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRV----KDERCWEIIDNIKGTEYTLSGL 235
           +++TV W   +E + + +   E + T F G   V         W I+ NIK   YT+ GL
Sbjct: 397 DTITVHWTSDDEFSVVSY---ELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGL 453

Query: 236 KFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKV--EDTCVEWDPT 293
           +  +KY+ F V+A N+A     S+P  L+T +  F LD  S+H  LKV  ++  VE D +
Sbjct: 454 QSGTKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES 511

Query: 294 GGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE-SYTVLGDTAIESGQ 352
             K             +S TP                  +RFT + SY V G+  I+SG+
Sbjct: 512 SSK-------------KSHTP------------------ERFTSQGSYGVAGNVFIDSGR 540

Query: 353 HYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSW--CIHVNNWLQNTFAAKHNNKVKA 410
           HYWEV        Y++G+AYK+  K + +GK + SW  C   NNW+      +HN+K   
Sbjct: 541 HYWEV-VISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV-----VRHNSKEIP 594

Query: 411 LDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGM 469
           ++      ++G+  D+D G ++FYDA +   LY+F   F QPV P F VW   L++ TG+
Sbjct: 595 IEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGL 654

Query: 470 QVP 472
            +P
Sbjct: 655 PIP 657


>gi|4557753 midline 1 [Homo sapiens]
          Length = 667

 Score =  217 bits (553), Expect = 2e-56
 Identities = 150/483 (31%), Positives = 245/483 (50%), Gaps = 54/483 (11%)

Query: 2   DSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEV 61
           D  K+ L+  ++ L  +N E++  +  L  T + V+ N+S   ++L EE D L  I+ + 
Sbjct: 217 DKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQR 276

Query: 62  KESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIK 121
           ++ +   IK+ +  + ++L  QI+ C   +E S  L+  A  SL   +   F + A+ I 
Sbjct: 277 RQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNIT 336

Query: 122 DRVTMASAFRLSLKPKV--SDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVAD 179
           +RV+MA+A    L P++  +D      +DFS+E+++L+ L +L  P  P I    C  + 
Sbjct: 337 ERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASY 396

Query: 180 NSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRV----KDERCWEIIDNIKGTEYTLSGL 235
           +++TV W   +E + + +   E + T F G   V         W I+ NIK   YT+ GL
Sbjct: 397 DTITVHWTSDDEFSVVSY---ELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGL 453

Query: 236 KFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKV--EDTCVEWDPT 293
           +  +KY+ F V+A N+A     S+P  L+T +  F LD  S+H  LKV  ++  VE D +
Sbjct: 454 QSGTKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES 511

Query: 294 GGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE-SYTVLGDTAIESGQ 352
             K             +S TP                  +RFT + SY V G+  I+SG+
Sbjct: 512 SSK-------------KSHTP------------------ERFTSQGSYGVAGNVFIDSGR 540

Query: 353 HYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSW--CIHVNNWLQNTFAAKHNNKVKA 410
           HYWEV        Y++G+AYK+  K + +GK + SW  C   NNW+      +HN+K   
Sbjct: 541 HYWEV-VISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV-----VRHNSKEIP 594

Query: 411 LDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGM 469
           ++      ++G+  D+D G ++FYDA +   LY+F   F QPV P F VW   L++ TG+
Sbjct: 595 IEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGL 654

Query: 470 QVP 472
            +P
Sbjct: 655 PIP 657


>gi|15451852 midline 1 [Homo sapiens]
          Length = 667

 Score =  217 bits (553), Expect = 2e-56
 Identities = 150/483 (31%), Positives = 245/483 (50%), Gaps = 54/483 (11%)

Query: 2   DSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEV 61
           D  K+ L+  ++ L  +N E++  +  L  T + V+ N+S   ++L EE D L  I+ + 
Sbjct: 217 DKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQR 276

Query: 62  KESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIK 121
           ++ +   IK+ +  + ++L  QI+ C   +E S  L+  A  SL   +   F + A+ I 
Sbjct: 277 RQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNIT 336

Query: 122 DRVTMASAFRLSLKPKV--SDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVAD 179
           +RV+MA+A    L P++  +D      +DFS+E+++L+ L +L  P  P I    C  + 
Sbjct: 337 ERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASY 396

Query: 180 NSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRV----KDERCWEIIDNIKGTEYTLSGL 235
           +++TV W   +E + + +   E + T F G   V         W I+ NIK   YT+ GL
Sbjct: 397 DTITVHWTSDDEFSVVSY---ELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGL 453

Query: 236 KFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKV--EDTCVEWDPT 293
           +  +KY+ F V+A N+A     S+P  L+T +  F LD  S+H  LKV  ++  VE D +
Sbjct: 454 QSGTKYI-FMVKAINQA-GSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDES 511

Query: 294 GGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE-SYTVLGDTAIESGQ 352
             K             +S TP                  +RFT + SY V G+  I+SG+
Sbjct: 512 SSK-------------KSHTP------------------ERFTSQGSYGVAGNVFIDSGR 540

Query: 353 HYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSW--CIHVNNWLQNTFAAKHNNKVKA 410
           HYWEV        Y++G+AYK+  K + +GK + SW  C   NNW+      +HN+K   
Sbjct: 541 HYWEV-VISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWV-----VRHNSKEIP 594

Query: 411 LDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGM 469
           ++      ++G+  D+D G ++FYDA +   LY+F   F QPV P F VW   L++ TG+
Sbjct: 595 IEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGL 654

Query: 470 QVP 472
            +P
Sbjct: 655 PIP 657


>gi|223890259 midline 2 isoform 2 [Homo sapiens]
          Length = 705

 Score =  203 bits (517), Expect = 3e-52
 Identities = 142/486 (29%), Positives = 242/486 (49%), Gaps = 46/486 (9%)

Query: 5   KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
           K+ L+  ++ L  +N E++N +  L    + V+ N++   ++L EE D L  I+ + K+ 
Sbjct: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQM 299

Query: 65  MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
           +   IK+ +  K ++L  Q++ C   LE S  L+  A   L   +   F ++A+ I +RV
Sbjct: 300 IAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERV 359

Query: 125 TMASAFRLSLKPKVS--DNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 182
            MA+A    L P ++  D   +  +DFS+E+++L+ L +L  P  P I    C  + +++
Sbjct: 360 AMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTI 419

Query: 183 TVAWRMPEEDNKIDHFILEHR----KTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFD 238
           TV W + +++  I  + L++     + NF  L    D   W I+ NIK   YT+ GL+  
Sbjct: 420 TVHW-ISDDEFSISSYELQYTIFTGQANFISLYNSVDS--WMIVPNIKQNHYTVHGLQSG 476

Query: 239 SKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQ 298
           ++Y+ F V+A N+A     S+P  L+T +  F LD   +H  LK+ +  ++ +       
Sbjct: 477 TRYI-FIVKAINQA-GSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEK-----D 529

Query: 299 ESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGES-YTVLGDTAIESGQHYWEV 357
           ES +K      +S TP                  +RF+G   Y   G+  I+SG HYWEV
Sbjct: 530 ESSLK------KSHTP------------------ERFSGTGCYGAAGNIFIDSGCHYWEV 565

Query: 358 KAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVP- 416
                   Y++G+AYK+  K + +GK  +SW     N   + F  +HNNK   +DV    
Sbjct: 566 -VMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCN---SNFVVRHNNKEMLVDVPPHL 621

Query: 417 EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAVR 476
           +++GV  D+D   LSFYD  +   L++F   F  PV P F +W   L + +G+  P  + 
Sbjct: 622 KRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFID 681

Query: 477 TLQKSE 482
             ++ E
Sbjct: 682 YPERQE 687


>gi|223890257 midline 2 isoform 1 [Homo sapiens]
          Length = 735

 Score =  192 bits (489), Expect = 5e-49
 Identities = 143/514 (27%), Positives = 243/514 (47%), Gaps = 72/514 (14%)

Query: 5   KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
           K+ L+  ++ L  +N E++N +  L    + V+ N++   ++L EE D L  I+ + K+ 
Sbjct: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQM 299

Query: 65  MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
           +   IK+ +  K ++L  Q++ C   LE S  L+  A   L   +   F ++A+ I +RV
Sbjct: 300 IAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERV 359

Query: 125 TMASAFRLSLKPKVS--DNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 182
            MA+A    L P ++  D   +  +DFS+E+++L+ L +L  P  P I    C  + +++
Sbjct: 360 AMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTI 419

Query: 183 TVAWRMPEEDNKIDHFILEHR----KTNF--------------------------DGLPR 212
           TV W + +++  I  + L++     + NF                           G PR
Sbjct: 420 TVHW-ISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPR 478

Query: 213 --VKDERCWEIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNF 270
                   W I+ NIK   YT+ GL+  ++Y+ F V+A N+A     S+P  L+T +  F
Sbjct: 479 GLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYI-FIVKAINQA-GSRNSEPTRLKTNSQPF 536

Query: 271 NLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRG 330
            LD   +H  LK+ +  ++ +       ES +K      +S TP                
Sbjct: 537 KLDPKMTHKKLKISNDGLQMEK-----DESSLK------KSHTP---------------- 569

Query: 331 SRDRFTGES-YTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWC 389
             +RF+G   Y   G+  I+SG HYWEV        Y++G+AYK+  K + +GK  +SW 
Sbjct: 570 --ERFSGTGCYGAAGNIFIDSGCHYWEV-VMGSSTWYAIGIAYKSAPKNEWIGKNASSWV 626

Query: 390 IHVNNWLQNTFAAKHNNKVKALDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKF 448
               N   + F  +HNNK   +DV    +++GV  D+D   LSFYD  +   L++F   F
Sbjct: 627 FSRCN---SNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTF 683

Query: 449 TQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSE 482
             PV P F +W   L + +G+  P  +   ++ E
Sbjct: 684 ILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQE 717


>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
          Length = 759

 Score =  119 bits (299), Expect = 5e-27
 Identities = 116/497 (23%), Positives = 201/497 (40%), Gaps = 72/497 (14%)

Query: 5   KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
           K+ L + ++ +    D +Q  I  L   ++  + +      E+ +    L ++L+E + S
Sbjct: 271 KDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRAS 330

Query: 65  MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
           ++  I++ Q  +   L +QI +  + L+ S  L+ +A   L   +   F +AA+Q+ +R+
Sbjct: 331 LLQAIEECQQERLARLSAQIQEHRSLLDGSG-LVGYAQEVLKETDQPCFVQAAKQLHNRI 389

Query: 125 TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSVTV 184
             A+    + +P  S +  H  +D  +E ++L  L FL VP+AP ID       D  + +
Sbjct: 390 ARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQ-IFL 448

Query: 185 AWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMNF 244
            WR+P       H+ +E R+T+   +P       W+  + ++GT   L      S Y+  
Sbjct: 449 CWRLPPHSPPAWHYTVEFRRTD---VPAQPGPTRWQRREEVRGTSALLENPDTGSVYV-L 504

Query: 245 RVRACNKAVAGEYSDPVTLET---KALNFNLDNSSSHLNLKVEDTCVEWDPTGGKGQESK 301
           RVR CNKA  GEYS+ V L T     L+F LD+               W    G  +E  
Sbjct: 505 RVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDS--------------RW----GASRERL 546

Query: 302 IKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTG---ESYTVLGDTAIESGQHYWEVK 358
              K+ +     P           P +  +    TG       VLGD A+  G+ YW   
Sbjct: 547 AISKDQRAVRSVPG---------LPLLLAADRLLTGCHLSVDVVLGDVAVTQGRSYWACA 597

Query: 359 AQKDCKSYSVGVAYKT------------------------LGKFDQLGKTNTSWC---IH 391
                    VGV  ++                         G  D   + +  +    I 
Sbjct: 598 VDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTIG 657

Query: 392 VNNWLQNTFAAKH------NNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFK 445
           +   L  + A+ +      +       V +P ++G+  D++ G++SF DA S + L    
Sbjct: 658 MGKILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECP 717

Query: 446 TKFTQPVLPGFMVWCGG 462
              + PV P F    GG
Sbjct: 718 LDCSGPVCPAFCFIGGG 734


>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
          Length = 728

 Score =  115 bits (289), Expect = 7e-26
 Identities = 120/497 (24%), Positives = 210/497 (42%), Gaps = 76/497 (15%)

Query: 5   KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
           KE L + I  L  K  ++++ I  L+  +K  + N      E    F+ L+ +L+E K S
Sbjct: 257 KEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSS 316

Query: 65  MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
           ++  I   +  +  + Q+Q+ +    LEN+  L+ +A   L   +   F + A+Q+  R+
Sbjct: 317 VLKAIDSSKKLRLDKFQTQMEEYQGLLENN-GLVGYAQEVLKETDQSCFVQTAKQLHLRI 375

Query: 125 TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVP-KAPEIDPVECLVADNSVT 183
             A+    S +P    +    +V+ S++ ++L  L F       PEI+  +  V +N++ 
Sbjct: 376 QKATESLKSFRPAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPEINEEQSKVYNNAL- 434

Query: 184 VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN 243
           + W  PE+D K D ++LE+RK N D      DE  W  I+ + GT   +  L+  S Y  
Sbjct: 435 INWHHPEKD-KADSYVLEYRKINRD------DEMSWNEIE-VCGTSKIIQDLENSSTYA- 485

Query: 244 FRVRACNKAVAGEYSDPVTLET---KALNFNLDN----SSSHLNLKVEDTCVEWDPTGGK 296
           FRVRA   ++    S  + L T      +F  D     ++ HL L ++   VE       
Sbjct: 486 FRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNNEHLLLNLKRDRVE------- 538

Query: 297 GQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWE 356
                       G +   + +R  VG            +T   Y ++GDT I  G+H+W 
Sbjct: 539 ---------SRAGFNLLLAAERIQVG-----------YYTSLDY-IIGDTGITKGKHFWA 577

Query: 357 VKAQKDCKSYSVGVAYK------------------------TLGKFDQLGKTNTSWCIHV 392
            + +       VGVA                            G  D    ++  + + V
Sbjct: 578 FRVEPYSYLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTL-V 636

Query: 393 NNWLQNTFAAK---HNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFT 449
              +Q  F  K    +N+ +   + +P  IG+F D D G++ FYD +  + LY  +   +
Sbjct: 637 TIGMQKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCS 696

Query: 450 QPVLPGF-MVWCGGLSL 465
             + P F ++  GG+ L
Sbjct: 697 HTLYPAFALMGSGGIQL 713


>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
          Length = 783

 Score =  109 bits (273), Expect = 5e-24
 Identities = 112/448 (25%), Positives = 192/448 (42%), Gaps = 69/448 (15%)

Query: 5   KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
           K  L + ++ +++K  E + F+  L + L+ +QEN  +  + L  + D+L   L   K  
Sbjct: 348 KAQLSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAK 407

Query: 65  MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
           ++  + +E+  K + +  QI+ C   L  S  L+E+    +   +P  F + +  +  RV
Sbjct: 408 LLTKVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRV 467

Query: 125 TMASA--FRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLP----VPKAPEIDPVECLVA 178
            ++     + +L+PKVS     L +D     Q +  L F+     VP  P +   +C   
Sbjct: 468 QVSQEQWVKGALEPKVSAEF-DLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTR 526

Query: 179 DNSVTVAWRMPE-EDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKF 237
           +NSVT+AWRMP    + +D +ILE        L      +  E+    K T  T+ GL F
Sbjct: 527 NNSVTLAWRMPPFTHSPVDGYILE--------LDDGAGGQFREVYVG-KETLCTIDGLHF 577

Query: 238 DSKYMNFRVRACNKAVAGEYSDPVTLETKALN-FNLDNSSSHLNLKVEDTCVEWDPTGGK 296
           +S Y N RV+A N +  G YS  V L+T  +  F  D +S H ++ +             
Sbjct: 578 NSTY-NARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIIL------------- 623

Query: 297 GQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWE 356
                     N  ++ T S                    + +   VLG  A   G HYWE
Sbjct: 624 ---------SNDNQTATCS--------------------SYDDRVVLGTAAFSKGVHYWE 654

Query: 357 VKAQK--DCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNN---WLQNTFAAKHNNKVKAL 411
           +   +  +    + GVA  ++ K   LGK + +W ++V+N   W  +     H N+ +  
Sbjct: 655 LHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMH--CNSHTNRTEG- 711

Query: 412 DVTVPEKIGVFCDFDGGQLSFYDANSKQ 439
            V     +GV  D +   L+F+    +Q
Sbjct: 712 GVCKGATVGVLLDLNKHTLTFFINGQQQ 739


>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
          Length = 710

 Score =  103 bits (258), Expect = 3e-22
 Identities = 111/455 (24%), Positives = 188/455 (41%), Gaps = 81/455 (17%)

Query: 5   KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
           K  L + ++ L+++  E + F+  L + ++ +QENS    + L  + D+L   L+  K  
Sbjct: 274 KSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQ 333

Query: 65  MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
           ++  + +E   K + ++ QIS C   L  +  L+E+    +   +P  F + +  +  RV
Sbjct: 334 LLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393

Query: 125 --TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFL------PVPKAPEIDPVECL 176
             T     + +L P+++ +   L +D S   Q +  L F+      PVP  P +   EC 
Sbjct: 394 HLTEDQWGKGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECC 452

Query: 177 VADNSVTVAWRMPEEDN-KIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGL 235
             +NS T++W+ P       D +ILE    N      V            K T  T+ GL
Sbjct: 453 THNNSATLSWKQPPLSTVPADGYILELDDGNGGQFREVYVG---------KETMCTVDGL 503

Query: 236 KFDSKYMNFRVRACNKAVAGEYSDPVTLETKALN-FNLDNSSSHLNLKVED-----TCVE 289
            F+S Y N RV+A NK     YS  + L+T  +  F  D  S+H ++ + +     TC  
Sbjct: 504 HFNSTY-NARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTVTCSS 562

Query: 290 WDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIE 349
           +D                                         DR       VLG T   
Sbjct: 563 YD-----------------------------------------DR------VVLGKTGFS 575

Query: 350 SGQHYWEVKAQK--DCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNN---WLQNTFAAKH 404
            G HYWE+   +  +    + GVA   + K   LGK + +W ++V+N   W  +     H
Sbjct: 576 KGIHYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHN--NSH 633

Query: 405 NNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQ 439
            N+ +   +T    IGV  D +   L+F+  + +Q
Sbjct: 634 TNRTEG-GITKGATIGVLLDLNRKNLTFFINDEQQ 667


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 99.4 bits (246), Expect = 7e-21
 Identities = 118/533 (22%), Positives = 218/533 (40%), Gaps = 72/533 (13%)

Query: 5    KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
            K  L   +  L  K+  I+ F+  +      ++EN S     L+E+ + +   +    + 
Sbjct: 3546 KVQLAEFLENLQEKSLRIEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDE 3605

Query: 65   MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
                 ++ + +K + L  Q+     +++ +++ LE   R  +  +   F  +  +I +R+
Sbjct: 3606 KAQSFEEVKKKKMEFLHEQMVHFLQSMDTAKDTLETIVREAEELDEAVFLTSFEEINERL 3665

Query: 125  TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNS-VT 183
              A     SL+   +        D S  R   Q LK + VP+ P ++P E   A ++ + 
Sbjct: 3666 LSAMESTASLEKMPAAFSLFEHYDDSSARSD-QMLKQVAVPQPPRLEPQEPNSATSTTIA 3724

Query: 184  VAWRM----------------PEEDNKIDHFILEHR---KTNFDGLPRVKDERCWEIIDN 224
            V W M                P++D +++  + E+R   K ++     ++ +RC+++   
Sbjct: 3725 VYWSMNKEDVIDSFQVYCMEEPQDDQEVNELVEEYRLTVKESYCIFEDLEPDRCYQVW-- 3782

Query: 225  IKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSHLNLKVE 284
            +    +T  G    S+   FR       +  E    V   T  + +      +     +E
Sbjct: 3783 VMAVNFT--GCSLPSERAIFRTAPSTPVIRAE-DCTVCWNTATIRWRPTTPEATETYTLE 3839

Query: 285  DTCVEWDPTG-GKGQESKIKGKENK----------------GRSGTPSPKRTSV----GS 323
              C +  P G G    S IKG + K                   GT      ++    G+
Sbjct: 3840 -YCRQHSPEGEGLRSFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAALISTRGT 3898

Query: 324  R--------PPAVR----------GSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKS 365
            R         PA+           G R R T E  +VLG+     GQHYWE     DC +
Sbjct: 3899 RFLLLRETAHPALHISSSGTVISFGERRRLT-EIPSVLGEELPSCGQHYWETTVT-DCPA 3956

Query: 366  YSVGVAYKTLGKFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTV-PEKIGVFCD 424
            Y +G+   +  +   LG+  TSW +H +   + TF   ++  V  + VT  P ++G+  D
Sbjct: 3957 YRLGICSSSAVQAGALGQGETSWYMHCSEPQRYTFF--YSGIVSDVHVTERPARVGILLD 4014

Query: 425  FDGGQLSFYDANSKQLLYSFKTKFTQPVLPGF-MVWCGGLSLSTGMQVPSAVR 476
            ++  +L F +A S+QLL+  + +F + V P F +   G  +L  G++ P +VR
Sbjct: 4015 YNNQRLIFINAESEQLLFIIRHRFNEGVHPAFALEKPGKCTLHLGIEPPDSVR 4067


>gi|46409324 SPRY domain containing 4 [Homo sapiens]
          Length = 207

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 48/155 (30%), Positives = 80/155 (51%), Gaps = 4/155 (2%)

Query: 321 VGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQ 380
           VG  P  V  + +RF  E   VL DTA+ SG+HYWEV  ++  + + +GVA   + +   
Sbjct: 57  VGLEPTKVALNVERFR-EWAVVLADTAVTSGRHYWEVTVKRS-QQFRIGVADVDMSRDSC 114

Query: 381 LGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQL 440
           +G  + SW          T  A  N K     +  PEK+G+  +++  +LS  D +   +
Sbjct: 115 IGVDDRSWVFTYAQRKWYTMLA--NEKAPVEGIGQPEKVGLLLEYEAQKLSLVDVSQVSV 172

Query: 441 LYSFKTKFTQPVLPGFMVWCGGLSLSTGMQVPSAV 475
           +++ +T F  PV+P F +W G L   +G++VP  +
Sbjct: 173 VHTLQTDFRGPVVPAFALWDGELLTHSGLEVPEGL 207


>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
          Length = 550

 Score = 82.4 bits (202), Expect = 9e-16
 Identities = 72/270 (26%), Positives = 123/270 (45%), Gaps = 20/270 (7%)

Query: 5   KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
           K  L + ++ L+++  E + F+  L + ++ +QENS    + L  + D+L   L+  K  
Sbjct: 274 KSQLSQALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQ 333

Query: 65  MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
           ++  + +E   K + ++ QIS C   L  +  L+E+    +   +P  F + +  +  RV
Sbjct: 334 LLARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRV 393

Query: 125 --TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFL------PVPKAPEIDPVECL 176
             T     + +L P+++ +   L +D S   Q +  L F+      PVP  P +   EC 
Sbjct: 394 HLTEDQWGKGTLTPRMTTDF-DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECC 452

Query: 177 VADNSVTVAWRMPEEDN-KIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGL 235
             +NS T++W+ P       D +ILE    N      V            K T  T+ GL
Sbjct: 453 THNNSATLSWKQPPLSTVPADGYILELDDGNGGQFREVYVG---------KETMCTVDGL 503

Query: 236 KFDSKYMNFRVRACNKAVAGEYSDPVTLET 265
            F+S Y N RV+A NK     YS  + L+T
Sbjct: 504 HFNSTY-NARVKAFNKTGVSPYSKTLVLQT 532


>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 53/151 (35%), Positives = 75/151 (49%), Gaps = 9/151 (5%)

Query: 320 SVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTL---G 376
           SV   P   R    RFT  S  VLG    + G HYWEV+ QK+     VG+ Y ++   G
Sbjct: 480 SVAEMPQNYRPHPQRFTYCSQ-VLGLHCYKKGIHYWEVELQKN-NFCGVGICYGSMNRQG 537

Query: 377 KFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDAN 436
              +LG+ + SWC+    W     +A HNN  K L  T   ++GV  + D G + F+   
Sbjct: 538 PESRLGRNSASWCVE---WFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVA 594

Query: 437 SK-QLLYSFKTKFTQPVLPGFMVWCGGLSLS 466
            K  L+Y F+  FT+ + P F V+  G +LS
Sbjct: 595 DKVHLMYKFRVDFTEALYPAFWVFSAGATLS 625


>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
          Length = 353

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 52/159 (32%), Positives = 79/159 (49%), Gaps = 1/159 (0%)

Query: 4   QKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 63
           QK  L   IS L   ND +Q  I  L  + +  +ENS  +  EL ++FD+LY+ILDE K 
Sbjct: 166 QKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKS 225

Query: 64  SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQ-IKD 122
            ++  I QEQ +K   +++ I Q    L+ S +L+E A +SLD      F   A+Q IK 
Sbjct: 226 ELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKS 285

Query: 123 RVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKF 161
            V  +   +L    +  +NM    +D       L+ + F
Sbjct: 286 IVEASKGCQLGKTEQGFENMDFFTLDLEHIADALRAIDF 324


>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
           sapiens]
          Length = 749

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 77/320 (24%), Positives = 131/320 (40%), Gaps = 43/320 (13%)

Query: 161 FLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWE 220
           ++  P  P I   E    + +V + W      N +D + +E        L + +      
Sbjct: 465 YMTAPSPPIIKTKEIRSCEEAVLICWESGNL-NPVDSYTVE--------LTQAESPEASG 515

Query: 221 IIDNIKG--TEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNFNLDNSSSH 278
           + +++ G  T  ++  L+    Y+ + VRA N       S+P T+ T    F L+     
Sbjct: 516 VTESVVGIPTCESVVQLQPGRSYIIY-VRALNMGGPSVRSEPATVHTIGSYFRLN----- 569

Query: 279 LNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGE 338
                +DTC  W      G  +    +    R  +PS                 D     
Sbjct: 570 -----KDTCHPWLTISEDGLTAVRSERRTPARELSPS-----------------DTHFTR 607

Query: 339 SYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWCI-HVNNWLQ 397
              V+G+     G HYWEV+  +    Y VGVA+  + K + LG    SWC+ H     +
Sbjct: 608 CVAVMGNLIPVRGHHYWEVEVDEHL-DYRVGVAFADVRKQEDLGANCLSWCMRHTFASSR 666

Query: 398 NTFAAKHNNKVKALDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQPVLPGF 456
           + +   HN     + +TVP +KIG+  D++  +LSF++ +  Q LY+F  +  + V P F
Sbjct: 667 HKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCF 726

Query: 457 MVWCGG-LSLSTGMQVPSAV 475
            +   G L +  G+ +P  V
Sbjct: 727 SLEKPGCLKVHNGISMPKHV 746



 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 57/253 (22%), Positives = 112/253 (44%), Gaps = 8/253 (3%)

Query: 1   MDSQKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE 60
           ++S K+ + + +  L  +  E++NF + L      V+EN        +  ++ +   L +
Sbjct: 209 LESAKDEIHKNMYKLEKQIIEMENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQ 268

Query: 61  VKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQI 120
             E  I  + +++  K + L  Q+  C   L+  +EL+E     +  +E  +F K A  +
Sbjct: 269 KYEEKIQALGEKKKEKLEALYGQLVSCGENLDTCKELME-TIEEMCHEEKVDFIKDAVAM 327

Query: 121 KDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDP-VECLVAD 179
            DR+      +  ++           +DFS   Q++ ++  +P P AP I+P V      
Sbjct: 328 ADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATG 387

Query: 180 NSVTVAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDS 239
           +SV V W +  +D  ++ + L +R    D  P        E    +K T  +++ L  ++
Sbjct: 388 SSVRVCWSLYSDDT-VESYQLSYRPVQ-DSSPGTDQA---EFTVTVKETYCSVTNLVPNT 442

Query: 240 KYMNFRVRACNKA 252
           +Y  F V A N+A
Sbjct: 443 QY-EFWVTAHNRA 454


>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
          Length = 452

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 48/159 (30%), Positives = 83/159 (52%), Gaps = 1/159 (0%)

Query: 4   QKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 63
           QK  L   I+ L   ND +Q  I  L  T K ++E       EL E+FD LY IL+E K 
Sbjct: 168 QKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKN 227

Query: 64  SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 123
            M   I + Q  K + +++ I + ++ LEN  +L+E   + +D  E   F + A+ +  +
Sbjct: 228 EMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKK 287

Query: 124 VTMAS-AFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKF 161
           ++ AS AF++       +NM H  V+ ++E ++++ + F
Sbjct: 288 ISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDF 326


>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
          Length = 548

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 48/159 (30%), Positives = 83/159 (52%), Gaps = 1/159 (0%)

Query: 4   QKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 63
           QK  L   I+ L   ND +Q  I  L  T K ++E       EL E+FD LY IL+E K 
Sbjct: 168 QKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKN 227

Query: 64  SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 123
            M   I + Q  K + +++ I + ++ LEN  +L+E   + +D  E   F + A+ +  +
Sbjct: 228 EMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKK 287

Query: 124 VTMAS-AFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKF 161
           ++ AS AF++       +NM H  V+ ++E ++++ + F
Sbjct: 288 ISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDF 326


>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
          Length = 540

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 48/159 (30%), Positives = 83/159 (52%), Gaps = 1/159 (0%)

Query: 4   QKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 63
           QK  L   I+ L   ND +Q  I  L  T K ++E       EL E+FD LY IL+E K 
Sbjct: 168 QKSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKN 227

Query: 64  SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 123
            M   I + Q  K + +++ I + ++ LEN  +L+E   + +D  E   F + A+ +  +
Sbjct: 228 EMTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKK 287

Query: 124 VTMAS-AFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKF 161
           ++ AS AF++       +NM H  V+ ++E ++++ + F
Sbjct: 288 ISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDF 326


>gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]
          Length = 432

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 48/148 (32%), Positives = 74/148 (50%), Gaps = 8/148 (5%)

Query: 317 KRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLG 376
           +  +V  RP   R S +RF+     VL   A+ SG+HYWEV   ++C  ++VGVA   + 
Sbjct: 279 RTVTVSHRPQPYRWSCERFSTSQ--VLCSQALSSGKHYWEVDT-RNCSHWAVGVASWEMS 335

Query: 377 KFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDA- 435
           +   LG+T  S C+      Q   +A H  K   L    P  +G++ + + G+L+FY   
Sbjct: 336 RDQVLGRTMDSCCVEWKGTSQ--LSAWHMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVD 393

Query: 436 NSKQLLYSFKTKFTQPVLPGFMVWCGGL 463
           N ++LLY      + P+ P F  W  GL
Sbjct: 394 NQEKLLYECTISASSPLYPAF--WLYGL 419


>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
          Length = 358

 Score = 69.7 bits (169), Expect = 6e-12
 Identities = 43/161 (26%), Positives = 84/161 (52%), Gaps = 1/161 (0%)

Query: 4   QKEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKE 63
           QK  L   I+ L   ND +Q  I  +    + +++NS      L++ F+SL ++L+E K 
Sbjct: 170 QKSELSDGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKG 229

Query: 64  SMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDR 123
            ++  + +EQ  K Q ++  I Q  + LE S +L+E A +S++  +   + + A+++ ++
Sbjct: 230 ELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINK 289

Query: 124 VTMASAFRLSLKPKVS-DNMTHLMVDFSQERQMLQTLKFLP 163
           V   S   L+ +P+   ++M    V      +ML+T+ F P
Sbjct: 290 VGAMSKVELAGRPEPGYESMEQFTVRVEHVAEMLRTIDFQP 330


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 96/425 (22%), Positives = 171/425 (40%), Gaps = 66/425 (15%)

Query: 37  QENSSNILSELDEEFDSLYSILDEVKESMINCIKQEQARKSQELQSQISQCNNALENSEE 96
           +    N + E   +F +L+     VK+  I C +   + K Q+    I     A     E
Sbjct: 89  KRQKENAMCEKHNQFLTLFC----VKDLEILCTQCSFSTKHQK--HYICPIKKAASYHRE 142

Query: 97  LLEFATRSLDIKEPEEFSKAARQIKDRVTMASAFRLSLKPKVSDNMTHLMVDFSQERQML 156
           +LE +         E       +++  + +  +  + LK KV      +  +F Q R  L
Sbjct: 143 ILEGSL--------EPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINSEFEQIRLFL 194

Query: 157 QTLKFLPVPKAPEIDPVECLVADNSVTVAWRMPEEDNKIDHFI--LEHRKTNFDGLPRVK 214
           Q           E + +   + D  + +  ++ E   ++  ++  L+H     +G     
Sbjct: 195 QN----------EQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQS 244

Query: 215 DERCWEIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSD-PVTLETKALNFNLD 273
           +    E++   K   +    LK    + +FR+     ++  +YS     ++   ++  LD
Sbjct: 245 N---LELLTQAKSMHHKYQNLKCPELF-SFRLTKYGFSLPPQYSGLDRIIKPFQVDVILD 300

Query: 274 NSSSHLNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRD 333
            +++H  L V +             + K    E K R+    P+R  V    PAV GS+ 
Sbjct: 301 LNTAHPQLLVSE-------------DRKAVRYERKKRNICYDPRRFYVC---PAVLGSQ- 343

Query: 334 RFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKF--DQLGKTNTSWCIH 391
           RF+             SG+HYWEV+     K + +GV    L +   DQ       W I 
Sbjct: 344 RFS-------------SGRHYWEVEVGNKPK-WILGVCQDCLLRNWQDQPSVLGGFWAI- 388

Query: 392 VNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFTQP 451
              ++++ + A      + L V  P KIG+F D++ G LSFY+ N + +LY+F   FT+ 
Sbjct: 389 -GRYMKSGYVASGPKTTQLLPVVKPSKIGIFLDYELGDLSFYNMNDRSILYTFNDCFTEA 447

Query: 452 VLPGF 456
           V P F
Sbjct: 448 VWPYF 452


>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
          Length = 400

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 40/153 (26%), Positives = 81/153 (52%), Gaps = 1/153 (0%)

Query: 12  ISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKESMINCIKQ 71
           I+ L   ND +Q  I  +    + +++NS      L++ F+SL ++L+E K  ++  + +
Sbjct: 220 IAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAR 279

Query: 72  EQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVTMASAFR 131
           EQ  K Q ++  I Q  + LE S +L+E A +S++  +   + + A+++ ++V   S   
Sbjct: 280 EQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVE 339

Query: 132 LSLKPKVS-DNMTHLMVDFSQERQMLQTLKFLP 163
           L+ +P+   ++M    V      +ML+T+ F P
Sbjct: 340 LAGRPEPGYESMEQFTVRVEHVAEMLRTIDFQP 372


>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 8/132 (6%)

Query: 340 YTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGK-----FDQLGKTNTSWCIHVNN 394
           + VL      +G+HYWEV  Q+    + VG AY +L +       +LG    SWC+   +
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368

Query: 395 WLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYD-ANSKQLLYSFKTKFTQPVL 453
                F     ++++  D    +++GVF D++ G L+FYD       L++F+  F +P+ 
Sbjct: 369 LEYWAFHDGQRSRLRPRDDL--DRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLY 426

Query: 454 PGFMVWCGGLSL 465
           P   +W G +S+
Sbjct: 427 PALRLWEGAISI 438


>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 8/132 (6%)

Query: 340 YTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGK-----FDQLGKTNTSWCIHVNN 394
           + VL      +G+HYWEV  Q+    + VG AY +L +       +LG    SWC+   +
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368

Query: 395 WLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYD-ANSKQLLYSFKTKFTQPVL 453
                F     ++++  D    +++GVF D++ G L+FYD       L++F+  F +P+ 
Sbjct: 369 LEYWAFHDGQRSRLRPRDDL--DRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLY 426

Query: 454 PGFMVWCGGLSL 465
           P   +W G +S+
Sbjct: 427 PALRLWEGAISI 438


>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 8/132 (6%)

Query: 340 YTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGK-----FDQLGKTNTSWCIHVNN 394
           + VL      +G+HYWEV  Q+    + VG AY +L +       +LG    SWC+   +
Sbjct: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368

Query: 395 WLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYD-ANSKQLLYSFKTKFTQPVL 453
                F     ++++  D    +++GVF D++ G L+FYD       L++F+  F +P+ 
Sbjct: 369 LEYWAFHDGQRSRLRPRDDL--DRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLY 426

Query: 454 PGFMVWCGGLSL 465
           P   +W G +S+
Sbjct: 427 PALRLWEGAISI 438


>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
          Length = 526

 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 37/124 (29%), Positives = 61/124 (49%), Gaps = 7/124 (5%)

Query: 342 VLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGK--FDQLGKTNTSWCIHVNNWLQNT 399
           VLG     SG+HYWEV+   D   +++GV  + + K  FD +   N  W + +     N 
Sbjct: 347 VLGRETFTSGRHYWEVEVG-DRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYG---NG 402

Query: 400 FAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSF-KTKFTQPVLPGFMV 458
           + A    +        P ++G+F D++ G +SFY+ N    +Y+F    F+ P+ P F +
Sbjct: 403 YWALTPLRTPLPLAGPPRRVGIFLDYESGDISFYNMNDGSDIYTFSNVTFSGPLRPFFCL 462

Query: 459 WCGG 462
           W  G
Sbjct: 463 WSSG 466


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,579,547
Number of Sequences: 37866
Number of extensions: 871064
Number of successful extensions: 3487
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 188
Number of HSP's that attempted gapping in prelim test: 2912
Number of HSP's gapped (non-prelim): 632
length of query: 498
length of database: 18,247,518
effective HSP length: 106
effective length of query: 392
effective length of database: 14,233,722
effective search space: 5579619024
effective search space used: 5579619024
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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