BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|8923481 gem (nuclear organelle) associated protein 8 [Homo sapiens] (242 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|109715862 gem (nuclear organelle) associated protein 8 [Homo ... 510 e-145 gi|109715864 gem (nuclear organelle) associated protein 8 [Homo ... 510 e-145 gi|8923481 gem (nuclear organelle) associated protein 8 [Homo sa... 510 e-145 gi|4505257 moesin [Homo sapiens] 42 6e-04 gi|4506467 radixin [Homo sapiens] 40 0.002 gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 39 0.004 gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 38 0.007 gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 38 0.009 gi|210032790 hypothetical protein LOC27146 [Homo sapiens] 38 0.009 gi|56549694 enabled homolog isoform a [Homo sapiens] 37 0.015 gi|39930375 enabled homolog isoform b [Homo sapiens] 37 0.015 gi|148746195 trichohyalin [Homo sapiens] 37 0.015 gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 37 0.020 gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 36 0.034 gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 36 0.034 gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 36 0.034 gi|15721939 metastatic lymph node 51 [Homo sapiens] 35 0.045 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 35 0.045 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 35 0.059 gi|21396500 HIRA interacting protein 3 [Homo sapiens] 35 0.059 gi|71143123 U11/U12 snRNP 48K [Homo sapiens] 35 0.077 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 34 0.10 gi|122937247 unc-13 homolog A [Homo sapiens] 34 0.10 gi|215490056 meningioma expressed antigen 5 (hyaluronidase) isof... 34 0.13 gi|11024698 meningioma expressed antigen 5 (hyaluronidase) isofo... 34 0.13 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 34 0.13 gi|148762982 hypothetical protein LOC387640 [Homo sapiens] 34 0.13 gi|153085395 histone deacetylase 4 [Homo sapiens] 33 0.17 gi|8923421 seryl-tRNA synthetase 2 isoform b precursor [Homo sap... 33 0.17 gi|225579074 seryl-tRNA synthetase 2 isoform a precursor [Homo s... 33 0.17 >gi|109715862 gem (nuclear organelle) associated protein 8 [Homo sapiens] Length = 242 Score = 510 bits (1313), Expect = e-145 Identities = 242/242 (100%), Positives = 242/242 (100%) Query: 1 MAAVKASTSKATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSAL 60 MAAVKASTSKATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSAL Sbjct: 1 MAAVKASTSKATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSAL 60 Query: 61 LPQSSYDNEAAYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEE 120 LPQSSYDNEAAYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEE Sbjct: 61 LPQSSYDNEAAYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEE 120 Query: 121 EMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHDLYC 180 EMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHDLYC Sbjct: 121 EMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHDLYC 180 Query: 181 NTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQPKYWPVIPL 240 NTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQPKYWPVIPL Sbjct: 181 NTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQPKYWPVIPL 240 Query: 241 KF 242 KF Sbjct: 241 KF 242 >gi|109715864 gem (nuclear organelle) associated protein 8 [Homo sapiens] Length = 242 Score = 510 bits (1313), Expect = e-145 Identities = 242/242 (100%), Positives = 242/242 (100%) Query: 1 MAAVKASTSKATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSAL 60 MAAVKASTSKATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSAL Sbjct: 1 MAAVKASTSKATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSAL 60 Query: 61 LPQSSYDNEAAYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEE 120 LPQSSYDNEAAYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEE Sbjct: 61 LPQSSYDNEAAYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEE 120 Query: 121 EMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHDLYC 180 EMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHDLYC Sbjct: 121 EMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHDLYC 180 Query: 181 NTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQPKYWPVIPL 240 NTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQPKYWPVIPL Sbjct: 181 NTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQPKYWPVIPL 240 Query: 241 KF 242 KF Sbjct: 241 KF 242 >gi|8923481 gem (nuclear organelle) associated protein 8 [Homo sapiens] Length = 242 Score = 510 bits (1313), Expect = e-145 Identities = 242/242 (100%), Positives = 242/242 (100%) Query: 1 MAAVKASTSKATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSAL 60 MAAVKASTSKATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSAL Sbjct: 1 MAAVKASTSKATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSAL 60 Query: 61 LPQSSYDNEAAYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEE 120 LPQSSYDNEAAYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEE Sbjct: 61 LPQSSYDNEAAYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEE 120 Query: 121 EMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHDLYC 180 EMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHDLYC Sbjct: 121 EMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHDLYC 180 Query: 181 NTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQPKYWPVIPL 240 NTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQPKYWPVIPL Sbjct: 181 NTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQPKYWPVIPL 240 Query: 241 KF 242 KF Sbjct: 241 KF 242 >gi|4505257 moesin [Homo sapiens] Length = 577 Score = 41.6 bits (96), Expect = 6e-04 Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 12/139 (8%) Query: 97 GQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREE 156 G H Y R + T E Q + + E L N E+ ++ AE E+ + E Sbjct: 286 GNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERAMLEN----EKKKREMAEKEKEKIE 341 Query: 157 RRRQQQLDAERL----DSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKI 212 R +++ + ERL + A +L TRR++E ER +R Q+E ++L + Sbjct: 342 REKEELM--ERLKQIEEQTKKAQQELEEQTRRALELEQER--KRAQSEAEKLAKERQEAE 397 Query: 213 QAMEAAVQLSFDKHCDRKQ 231 +A EA +Q S D+ ++Q Sbjct: 398 EAKEALLQASRDQKKTQEQ 416 >gi|4506467 radixin [Homo sapiens] Length = 583 Score = 40.0 bits (92), Expect = 0.002 Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 12/139 (8%) Query: 97 GQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREE 156 G H Y R + T E Q + + E L N E+ ++ AE E+ R E Sbjct: 286 GNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLEN----EKKKREIAEKEKERIE 341 Query: 157 RRRQQQLDAERL----DSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKI 212 R +++ + ERL + + A +L TR+++E ER +R + E +RL + A Sbjct: 342 REKEELM--ERLKQIEEQTIKAQKELEEQTRKALELDQER--KRAKEEAERLEKERRAAE 397 Query: 213 QAMEAAVQLSFDKHCDRKQ 231 +A A + + D+ +++Q Sbjct: 398 EAKSAIAKQAADQMKNQEQ 416 >gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial [Homo sapiens] Length = 213 Score = 38.9 bits (89), Expect = 0.004 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 8/118 (6%) Query: 92 HFRRSGQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETE 151 H R Q R +R D+ K+ + E E E E D TE R ET+ Sbjct: 43 HSERDRQRDRERNR---ERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETD 99 Query: 152 RHRE---ERRRQQQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYG 206 RH E ER++Q++ + ER+ + R + T+R E RQAE +R G Sbjct: 100 RHTETDRERQKQKEREMERVRDR-EREKQKEMGRERQTDRETDRERE-RQAERERETG 155 Score = 30.0 bits (66), Expect = 1.9 Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 20/117 (17%) Query: 95 RSGQHPRYSSRIQASTKEDQA-------LSKEEEMETESDAEVECDLSNMEITEELRQYF 147 R Q R R++ +E Q +E + E E AE E + TE+ R Sbjct: 108 RQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTED-RHRE 166 Query: 148 AETERHREERRRQQQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGER-RQAEMKR 203 E ER RE R+++ + ER + + R + T+R +R R++E +R Sbjct: 167 RERERKRERERKRETKERER-----------HTDMERERQRETDRKRDRQRESERER 212 >gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 isoform 2 [Homo sapiens] Length = 1651 Score = 38.1 bits (87), Expect = 0.007 Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 28/115 (24%) Query: 101 RYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQ 160 ++ R+Q S ++D E++ E E D D+ M I + L AE EERRRQ Sbjct: 1565 QFQKRLQESKQKD-----EDDEEEEDD-----DVDTMLIMQRLE---AERRARDEERRRQ 1611 Query: 161 QQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAM 215 QQL+ R +R E + ERR+ E +R D+ K+ + Sbjct: 1612 QQLEEMR---------------KREAEDRARQEEERRRQEEERTKRDAEEKVMVL 1651 >gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] Length = 285 Score = 37.7 bits (86), Expect = 0.009 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 9/113 (7%) Query: 95 RSGQHPRYSSRIQASTKEDQ-----ALSKEEEMETESDAEVECDLSNME---ITEELRQY 146 R + R R + +E Q + K+ E+ETE D + E ++ E E RQ Sbjct: 122 RQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQK 181 Query: 147 FAETERHREERRRQQQLDAER-LDSYVNADHDLYCNTRRSVEAPTERPGERRQ 198 ET R R+ R++++ D ER D + D Y + ER ER++ Sbjct: 182 QRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQR 234 Score = 31.6 bits (70), Expect = 0.65 Identities = 25/112 (22%), Positives = 44/112 (39%), Gaps = 3/112 (2%) Query: 95 RSGQHPRYSSRIQASTK---EDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETE 151 R Q R R +A + +D+ + K+ + + + D E + E ETE Sbjct: 60 RERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETE 119 Query: 152 RHREERRRQQQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKR 203 R+E R +Q+ D ++ + R +E +R ER E +R Sbjct: 120 TERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETER 171 >gi|210032790 hypothetical protein LOC27146 [Homo sapiens] Length = 1060 Score = 37.7 bits (86), Expect = 0.009 Identities = 28/118 (23%), Positives = 56/118 (47%), Gaps = 6/118 (5%) Query: 99 HPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERR 158 HP+ Q+ KE + +M+T+ +A E + + E+LR+ +TE EE++ Sbjct: 369 HPQQD---QSCLKECPCMKGGTDMQTKKEASAETEYMKQQYEEDLRKIKHQTE---EEKK 422 Query: 159 RQQQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAME 216 + +RL+ V + R SVEA ++ +A+++ + S +I+ +E Sbjct: 423 HLKDQLVKRLEDLVKKHTVEIKSVRSSVEAERKKLQREVEAQLEEVRKKSEKEIKQLE 480 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 37.0 bits (84), Expect = 0.015 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 12/116 (10%) Query: 105 RIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLD 164 R + + + L ++E +E + E + L + R+ ER R+ER RQ+QL+ Sbjct: 193 RERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLE 252 Query: 165 AERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQ 220 E+L+ + SVE P + + GDS+A ++AA Q Sbjct: 253 REQLE-WERERRISSAAAPASVETP-----------LNSVLGDSSASEPGLQAASQ 296 Score = 27.7 bits (60), Expect = 9.4 Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 3/102 (2%) Query: 105 RIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLD 164 ++Q ++ + + E E +E + E E R + ER R+ER RQ++L+ Sbjct: 146 QLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLE 205 Query: 165 -AERLDSYVNADHDLYCNTRRSVEAPTERPG--ERRQAEMKR 203 ERL+ + + R ER ER + E +R Sbjct: 206 RQERLERQERLERQERLDRERQERQERERLERLERERQERER 247 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 37.0 bits (84), Expect = 0.015 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 12/116 (10%) Query: 105 RIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLD 164 R + + + L ++E +E + E + L + R+ ER R+ER RQ+QL+ Sbjct: 193 RERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLE 252 Query: 165 AERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQ 220 E+L+ + SVE P + + GDS+A ++AA Q Sbjct: 253 REQLE-WERERRISSAAAPASVETP-----------LNSVLGDSSASEPGLQAASQ 296 Score = 27.7 bits (60), Expect = 9.4 Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 3/102 (2%) Query: 105 RIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLD 164 ++Q ++ + + E E +E + E E R + ER R+ER RQ++L+ Sbjct: 146 QLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLE 205 Query: 165 -AERLDSYVNADHDLYCNTRRSVEAPTERPG--ERRQAEMKR 203 ERL+ + + R ER ER + E +R Sbjct: 206 RQERLERQERLERQERLDRERQERQERERLERLERERQERER 247 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 37.0 bits (84), Expect = 0.015 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 6/93 (6%) Query: 111 KEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDS 170 KE++ L +EE E E L +E +ELR+ E E+ ++ RR+QQL ++ + Sbjct: 255 KEEEKLQEEEPQRQRELQEEEEQLRKLE-RQELRRERQEEEQQQQRLRREQQLRRKQEEE 313 Query: 171 YVNADHDLYCNTRRSVEAPTERPGERRQAEMKR 203 + RR + E+ ERR+ +++R Sbjct: 314 RREQQEE-----RREQQERREQQEERREQQLRR 341 Score = 36.2 bits (82), Expect = 0.026 Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 13/141 (9%) Query: 94 RRSGQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERH 153 RR +Y + +E+Q L +E E + E +C EEL+Q E + Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC-----REEEELQQ--EEEQLL 1124 Query: 154 REERRRQQQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQ 213 REER ++++ + ER Y + + + E P +RR+ E++R Y + Q Sbjct: 1125 REEREKRRRQELER--QYREEEE----VQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178 Query: 214 AMEAAVQLSFDKHCDRKQPKY 234 E ++ +K ++ +Y Sbjct: 1179 EEEQLLREEQEKRRQERERQY 1199 Score = 35.4 bits (80), Expect = 0.045 Identities = 32/134 (23%), Positives = 58/134 (43%), Gaps = 7/134 (5%) Query: 105 RIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFA----ETERHREERRRQ 160 R Q +E Q ++EE E E E ++ +E R+ + ETERH +ERR+Q Sbjct: 415 REQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQ 474 Query: 161 Q---QLDAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEA 217 Q + ER + ++ + + + E R E R+ + + + Q + + Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS 534 Query: 218 AVQLSFDKHCDRKQ 231 QL ++ R+Q Sbjct: 535 EQQLRREQEERREQ 548 Score = 35.4 bits (80), Expect = 0.045 Identities = 32/138 (23%), Positives = 58/138 (42%), Gaps = 16/138 (11%) Query: 98 QHPRYSSRIQASTKE--DQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHRE 155 + R R++ +E +Q L +EE E + E L E EE RQ ++E E Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641 Query: 156 ER----------RRQQQL----DAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEM 201 R RR+Q+L + ERL+ + +H+ + E E+ ER ++ + Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701 Query: 202 KRLYGDSAAKIQAMEAAV 219 + ++ A ++ V Sbjct: 702 PKWQWQLESEADARQSKV 719 Score = 30.8 bits (68), Expect = 1.1 Identities = 30/145 (20%), Positives = 59/145 (40%), Gaps = 20/145 (13%) Query: 95 RSGQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHR 154 R R ++ +E++ L +EEE + E E RQY E E R Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ-------ERERQYREEEELQR 1207 Query: 155 EERRRQQQLDAERLD-------SYVNA--DHDLYCNTRRSVE----APTERPGERRQAEM 201 ++R+++ + + +R D NA D+ +YC R + + ++ + Q ++ Sbjct: 1208 QKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDL 1267 Query: 202 KRLYGDSAAKIQAMEAAVQLSFDKH 226 + L G+ + + E D+H Sbjct: 1268 QHLLGEQQERDREQERRRWQQRDRH 1292 Score = 30.4 bits (67), Expect = 1.4 Identities = 25/108 (23%), Positives = 43/108 (39%), Gaps = 6/108 (5%) Query: 94 RRSGQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERH 153 RR + +Y + KE+Q L +E E + E EEL+Q + R Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE-----KKYREEEELQQEEEQLLRE 1006 Query: 154 REERRRQQQLDAE-RLDSYVNADHDLYCNTRRSVEAPTERPGERRQAE 200 E+RR+Q+ + + R + + + R ER + R+ E Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEE 1054 Score = 30.0 bits (66), Expect = 1.9 Identities = 31/135 (22%), Positives = 60/135 (44%), Gaps = 9/135 (6%) Query: 94 RRSGQHPRYSS-RIQASTKEDQALSKEEEMETESDAEVECDLSNME--ITEELRQYFAET 150 R+ +H Y+ +Q +++Q L +EEE E + + + E EE + E Sbjct: 882 RKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEE 941 Query: 151 ERHREERRRQQQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAA 210 + REER ++++ + ER D L ++ + E P +RR+ E ++ Y + Sbjct: 942 QLLREEREKRRRQERER---QYRKDKKL---QQKEEQLLGEEPEKRRRQEREKKYREEEE 995 Query: 211 KIQAMEAAVQLSFDK 225 Q E ++ +K Sbjct: 996 LQQEEEQLLREEREK 1010 Score = 29.6 bits (65), Expect = 2.5 Identities = 24/107 (22%), Positives = 47/107 (43%), Gaps = 10/107 (9%) Query: 105 RIQASTKEDQALSKEEE------METESDAEVECDLSNMEITEELRQYFAETERHREERR 158 R+Q + +Q L +E+E ++ E + +E + + E + + + EERR Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR 586 Query: 159 RQ--QQLDAERLDSYVNAD--HDLYCNTRRSVEAPTERPGERRQAEM 201 +Q ++ ERL+ + + L RR E P E R+ ++ Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633 Score = 28.9 bits (63), Expect = 4.2 Identities = 22/101 (21%), Positives = 42/101 (41%), Gaps = 1/101 (0%) Query: 103 SSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQ 162 + R + ++ Q +EE E ++E + E E Q + R E+R ++Q Sbjct: 464 TERHEQERRKQQLKRDQEEERRERWLKLE-EEERREQQERREQQLRREQEERREQRLKRQ 522 Query: 163 LDAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKR 203 + ERL + ++ L E +R E+R + +R Sbjct: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563 Score = 28.5 bits (62), Expect = 5.5 Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 19/99 (19%) Query: 107 QASTKEDQALSKEEEMETESDAEVECDLSNMEITEELR--QYFAETERHREERRRQQQLD 164 Q +E Q K+EE E E E EE R Q E E RE++ R++Q + Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357 Query: 165 AERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKR 203 RR + E+ ERR+ +++R Sbjct: 358 -----------------ERREQQLRREQEEERREQQLRR 379 Score = 28.1 bits (61), Expect = 7.2 Identities = 30/123 (24%), Positives = 51/123 (41%), Gaps = 13/123 (10%) Query: 94 RRSGQHPRYSSRIQASTKE--DQALSKEEEMETESDA---EVECDLSNMEITEELRQYFA 148 RR Q R +++ +E +Q L +E+E E E E + ++ E + Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386 Query: 149 ETERHREERRRQQQLDAE---RLDSYVNADHDLYCNTRRSVEAPTER-----PGERRQAE 200 + R ++ RR+QQL E R + + + L + E ER ERR+ Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446 Query: 201 MKR 203 +KR Sbjct: 447 LKR 449 Score = 28.1 bits (61), Expect = 7.2 Identities = 25/116 (21%), Positives = 46/116 (39%), Gaps = 3/116 (2%) Query: 111 KEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDS 170 +E+Q L ++E + E+ + EE Q ER R+ + +QQL + + Sbjct: 1348 REEQPLRRQERDRKFREEELRHQEQGRKFLEE-EQRLRRQERERKFLKEEQQLRCQEREQ 1406 Query: 171 YVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKH 226 + D D + ER + R+ E + + K +E QL ++H Sbjct: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF--LEEEQQLRQERH 1460 Score = 27.7 bits (60), Expect = 9.4 Identities = 21/101 (20%), Positives = 44/101 (43%), Gaps = 3/101 (2%) Query: 105 RIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQ--QQ 162 R + + +Q L +E+++ E E L + ++ ++H +ERR Q ++ Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449 Query: 163 LDAERLDSYVNADH-DLYCNTRRSVEAPTERPGERRQAEMK 202 ER D + + + RR + ++ ERR+ +K Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490 >gi|68299759 ecotropic viral integration site 5 [Homo sapiens] Length = 810 Score = 36.6 bits (83), Expect = 0.020 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 21/113 (18%) Query: 89 SSSHFRRSGQHP-RYSSRIQASTKEDQALSKEEEMETESDAEVEC------------DLS 135 +S+H RR+ Q ++Q + +++ L + AE+EC + Sbjct: 597 NSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRLREAD 656 Query: 136 NMEITEELRQYFAETERHREERRRQQQLD--------AERLDSYVNADHDLYC 180 ++ ELRQ+ AE E +EE + Q QL+ E D +H+L C Sbjct: 657 SIAAVAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQIAELNHELRC 709 >gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] Length = 290 Score = 35.8 bits (81), Expect = 0.034 Identities = 34/115 (29%), Positives = 53/115 (46%), Gaps = 10/115 (8%) Query: 95 RSGQHPRYSSRIQASTKE-DQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERH 153 R Q R R + +E D+ KE E +TE D + + + TE R E ++ Sbjct: 127 REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETE----TERERDREREKQKE 182 Query: 154 RE-ERRRQQQLDAER-LDSYVNADHDLYCNTRRSVEAPTERPGER---RQAEMKR 203 RE ER R +Q D E+ + + + D T+ + T+R GER R+ E +R Sbjct: 183 RETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQR 237 >gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] Length = 1113 Score = 35.8 bits (81), Expect = 0.034 Identities = 43/159 (27%), Positives = 65/159 (40%), Gaps = 21/159 (13%) Query: 11 ATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSALLPQSSYDNEA 70 AT Y HP Y H A S+ A+ S F P P +L P Sbjct: 140 ATAAAYYHPSYLAPHPFPHPAFRMDDSY---CLSALRSPF-YPIPTPGSLPP-------- 187 Query: 71 AYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKE-DQALSKEEEMETESDAE 129 +P + + H++ YP SH + H S + A + D+ L +E E E E + E Sbjct: 188 LHPSAMH-LHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERERE 246 Query: 130 VECDLSNMEITEELRQYFAETERHRE-ERRRQQQLDAER 167 E D E ++ E E+ RE E+ R+++ + ER Sbjct: 247 READ------REREKEREREREKEREQEKEREREKERER 279 >gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] Length = 1217 Score = 35.8 bits (81), Expect = 0.034 Identities = 43/159 (27%), Positives = 65/159 (40%), Gaps = 21/159 (13%) Query: 11 ATRPWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSALLPQSSYDNEA 70 AT Y HP Y H A S+ A+ S F P P +L P Sbjct: 244 ATAAAYYHPSYLAPHPFPHPAFRMDDSY---CLSALRSPF-YPIPTPGSLPP-------- 291 Query: 71 AYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKE-DQALSKEEEMETESDAE 129 +P + + H++ YP SH + H S + A + D+ L +E E E E + E Sbjct: 292 LHPSAMH-LHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRRERERERERERE 350 Query: 130 VECDLSNMEITEELRQYFAETERHRE-ERRRQQQLDAER 167 E D E ++ E E+ RE E+ R+++ + ER Sbjct: 351 READ------REREKEREREREKEREQEKEREREKERER 383 >gi|15721939 metastatic lymph node 51 [Homo sapiens] Length = 703 Score = 35.4 bits (80), Expect = 0.045 Identities = 32/124 (25%), Positives = 49/124 (39%), Gaps = 16/124 (12%) Query: 117 SKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADH 176 ++E E E+E E + LS+ E E+ E + EE + +L +E D+ Sbjct: 72 AEESECESEDGIEGDAVLSDYESAEDSE---GEEGEYSEEENSKVELKSEANDAV----- 123 Query: 177 DLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHC----DRKQP 232 N+ E E+P + +R GD + +E V KH DRK P Sbjct: 124 ----NSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNP 179 Query: 233 KYWP 236 Y P Sbjct: 180 AYIP 183 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 35.4 bits (80), Expect = 0.045 Identities = 30/113 (26%), Positives = 49/113 (43%), Gaps = 6/113 (5%) Query: 105 RIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLD 164 R+ KE Q L E + + +AE L ++ E+ R+ E + REER R+ Sbjct: 527 RMDPKEKERQRL---ENLRRKEEAE---QLRRQKVEEDKRRRLEEVKLKREERLRKVLQA 580 Query: 165 AERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEA 217 ER++ ++ TE+ E R AE K +A K++ +EA Sbjct: 581 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA 633 Score = 33.1 bits (74), Expect = 0.22 Identities = 30/114 (26%), Positives = 44/114 (38%), Gaps = 16/114 (14%) Query: 118 KEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHD 177 KEEE E A L+ E Q E ER +ERR Q++ + E Sbjct: 664 KEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE----------- 712 Query: 178 LYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQ 231 R+ E R ER QAE + + A ++Q + +L K + +Q Sbjct: 713 -----RQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 761 Score = 28.9 bits (63), Expect = 4.2 Identities = 16/74 (21%), Positives = 35/74 (47%) Query: 94 RRSGQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERH 153 RR + R Q ++++ L+++E + + E +L E L++ + E Sbjct: 693 RREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELE 752 Query: 154 REERRRQQQLDAER 167 ++++ +QQ AER Sbjct: 753 EKKKKEEQQRLAER 766 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 35.0 bits (79), Expect = 0.059 Identities = 19/70 (27%), Positives = 31/70 (44%) Query: 98 QHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREER 157 QHPR R Q +Q +E EME E + ++ E R +R R+ER Sbjct: 1129 QHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKER 1188 Query: 158 RRQQQLDAER 167 + ++ +E+ Sbjct: 1189 AKSKEKKSEK 1198 Score = 28.5 bits (62), Expect = 5.5 Identities = 30/130 (23%), Positives = 58/130 (44%), Gaps = 24/130 (18%) Query: 100 PRYSSRIQASTKEDQALSKEEEMETESDAEVE---------------------CDLSNME 138 PR SR + ++++A SKE++ E + A+ E L++ + Sbjct: 1174 PRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQ 1233 Query: 139 ITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGER-R 197 I ++ + AE + RE+RR++Q+ + E+ + A+ + R R +R R Sbjct: 1234 IVQKEAER-AERAKEREKRRKEQE-EEEQKEREKEAERERNRQLEREKRREHSRERDRER 1291 Query: 198 QAEMKRLYGD 207 + E +R GD Sbjct: 1292 ERERERDRGD 1301 >gi|21396500 HIRA interacting protein 3 [Homo sapiens] Length = 556 Score = 35.0 bits (79), Expect = 0.059 Identities = 30/130 (23%), Positives = 58/130 (44%), Gaps = 5/130 (3%) Query: 107 QASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERH----REERRRQQQ 162 +AS QA + EE E E + + T+ L++ E+E ++E+R ++ Sbjct: 184 KASVSRKQAREESEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQREEEV 243 Query: 163 LDAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLS 222 + E+ + D + ++ E +++++ KRL GDS ++ + EAA Sbjct: 244 EEEEKEEDEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAA-SSG 302 Query: 223 FDKHCDRKQP 232 D DR+ P Sbjct: 303 DDSGRDREPP 312 >gi|71143123 U11/U12 snRNP 48K [Homo sapiens] Length = 339 Score = 34.7 bits (78), Expect = 0.077 Identities = 39/154 (25%), Positives = 59/154 (38%), Gaps = 20/154 (12%) Query: 60 LLPQSSYDNEAAYPQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSR-------IQASTKE 112 L + + DN P+S+ + +DY +R H S I +E Sbjct: 192 LAAKINQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEE 251 Query: 113 DQALSKEEEMETESDAEV--ECDLSNMEITEELRQYF-AETERHREERRRQQQLDAERLD 169 +EE+ + E DAE E ++++ + Y AE RHR +R R Sbjct: 252 LSNHWQEEQEKAEDDAEKNEERRSASVDSRQSGGSYLDAECSRHRRDRSRSPHKRKR--- 308 Query: 170 SYVNADHDLYCNTRRSVEAPTERPGERRQAEMKR 203 N D D C +RR ER GER + +R Sbjct: 309 ---NKDKDKNCESRRR----KERDGERHHSHKRR 335 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 34.3 bits (77), Expect = 0.10 Identities = 31/112 (27%), Positives = 45/112 (40%), Gaps = 18/112 (16%) Query: 95 RSGQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHR 154 R + R R + + ED+ + E E E + E E + E RQ +TER R Sbjct: 185 RQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQ--RKTERER 242 Query: 155 E---ERRRQQQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKR 203 E ER R + + ER + R E +R +RRQ E +R Sbjct: 243 EKQAERERASERETER-------------DKERERERDRDRDRDRRQKERER 281 Score = 32.7 bits (73), Expect = 0.29 Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 16/119 (13%) Query: 94 RRSGQHPRYSSRI-QASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFA--ET 150 RR + R + R Q T+ D+ ++ E + E + E E + E R+ ET Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333 Query: 151 ERHRE-----ERRRQQQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGER-RQAEMKR 203 ER RE +R+RQ ++D ER + RR E ER ER RQ+ +R Sbjct: 334 ERDREKERERKRKRQTEMDRER-------NRQTGREGRRQAERERERERERDRQSARER 385 Score = 30.0 bits (66), Expect = 1.9 Identities = 32/123 (26%), Positives = 53/123 (43%), Gaps = 19/123 (15%) Query: 94 RRSGQHPRYSSRIQASTKE-----DQALSKEEEMETESDAEVECDLSNMEITEELRQYFA 148 +R + R R + + +E D+ + E E + DAE E + T+ RQ Sbjct: 116 QREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQ----TDRERQ--R 169 Query: 149 ETERHRE-----ERRRQQQLDAERLDSYVNADHDLYCNTRRSVEAPTERPGE---RRQAE 200 +TER+R+ E+ RQ++ + ER N D + R E E E +RQ + Sbjct: 170 QTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTD 229 Query: 201 MKR 203 +R Sbjct: 230 RER 232 Score = 30.0 bits (66), Expect = 1.9 Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 3/76 (3%) Query: 95 RSGQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFA--ETER 152 R + R R A +E++ ++ + + E + + E D TE+ R+ E+ER Sbjct: 369 RERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESER 428 Query: 153 HREE-RRRQQQLDAER 167 RE R R++Q ER Sbjct: 429 GRERGREREKQKGRER 444 Score = 29.6 bits (65), Expect = 2.5 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 8/98 (8%) Query: 112 EDQALSKEEEMETESD---AEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERL 168 +D+ ++++E E + E E D E+ R + +RHRE +R +++ + Sbjct: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRH--RKRDRHRERQRDREKERERQT 109 Query: 169 DSYVNADHDLYCNTRRSVEAPTERPGER---RQAEMKR 203 D + + N ++ E TER GER RQ + +R Sbjct: 110 DRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147 Score = 29.3 bits (64), Expect = 3.2 Identities = 28/114 (24%), Positives = 49/114 (42%), Gaps = 15/114 (13%) Query: 97 GQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREE 156 GQ R R A + ++ +E + +TE + + E + E+ RQ E ER RE+ Sbjct: 145 GQRERERQR-DAEKERERQTDRERQRQTERNRQKERE------REKNRQERRERERQREK 197 Query: 157 RRRQQQLDAER-------LDSYVNADHDLYCNTRRSVEAPTERPGERRQAEMKR 203 + + +ER ++ + + R + TER E +QAE +R Sbjct: 198 ENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERERE-KQAERER 250 >gi|122937247 unc-13 homolog A [Homo sapiens] Length = 1791 Score = 34.3 bits (77), Expect = 0.10 Identities = 41/219 (18%), Positives = 79/219 (36%), Gaps = 34/219 (15%) Query: 26 QHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSALLPQSSYDNEAAYP------QSFYDH 79 QH + + + YR + P+Y S P +S + P +S+ D Sbjct: 273 QHNDDPDSAVDDRDSDYRSETSNSIPPPYYTTSQ--PNASVHQYSVRPPPLGSRESYSDS 330 Query: 80 HVAWQDY-------PCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEEEMETESDAE--- 129 +++++ P SS + SG+ + SS++ D+ + +ME E D + Sbjct: 331 MHSYEEFSEPQALSPTGSSRYASSGELSQGSSQLSEDFDPDEHSLQGSDMEDERDRDSYH 390 Query: 130 ------------VECDLSNMEITEELRQYFAETE--RHREERRRQQQLDAERLDSYVNAD 175 D E+ E+L + E E EE +++ + L SY + Sbjct: 391 SCHSSVSYHKDSPRWDQDEEELEEDLEDFLEEEELPEDEEELEEEEEEVPDDLGSYAQRE 450 Query: 176 HDLYCNTR--RSVEAPTERPGERRQAEMKRLYGDSAAKI 212 + + + P PG+ +A + AK+ Sbjct: 451 DVAVAEPKDFKRISLPPAAPGKEDKAPVAPTEAPDMAKV 489 >gi|215490056 meningioma expressed antigen 5 (hyaluronidase) isoform b [Homo sapiens] Length = 863 Score = 33.9 bits (76), Expect = 0.13 Identities = 16/81 (19%), Positives = 36/81 (44%) Query: 113 DQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYV 172 D + K+EE + ++D ++ ++ ++ EEL+ + E E + + + + + Sbjct: 413 DMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIA 472 Query: 173 NADHDLYCNTRRSVEAPTERP 193 D N + V P E+P Sbjct: 473 PMQTDEQTNKEQFVPGPNEKP 493 >gi|11024698 meningioma expressed antigen 5 (hyaluronidase) isoform a [Homo sapiens] Length = 916 Score = 33.9 bits (76), Expect = 0.13 Identities = 16/81 (19%), Positives = 36/81 (44%) Query: 113 DQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYV 172 D + K+EE + ++D ++ ++ ++ EEL+ + E E + + + + + Sbjct: 466 DMVVEKQEETDHKNDNQILSEIVEAKMAEELKPMDTDKESIAESKSPEMSMQEDCISDIA 525 Query: 173 NADHDLYCNTRRSVEAPTERP 193 D N + V P E+P Sbjct: 526 PMQTDEQTNKEQFVPGPNEKP 546 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 33.9 bits (76), Expect = 0.13 Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 6/107 (5%) Query: 111 KEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDS 170 KE Q L E + + +AE L ++ E+ R+ E + REER R+ ER++ Sbjct: 537 KERQRL---ENLRRKEEAE---QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQ 590 Query: 171 YVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEA 217 ++ TE+ E R AE K +A K++ +EA Sbjct: 591 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA 637 Score = 33.1 bits (74), Expect = 0.22 Identities = 30/114 (26%), Positives = 44/114 (38%), Gaps = 16/114 (14%) Query: 118 KEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDSYVNADHD 177 KEEE E A L+ E Q E ER +ERR Q++ + E Sbjct: 668 KEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE----------- 716 Query: 178 LYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRKQ 231 R+ E R ER QAE + + A ++Q + +L K + +Q Sbjct: 717 -----RQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQ 765 Score = 28.9 bits (63), Expect = 4.2 Identities = 16/74 (21%), Positives = 35/74 (47%) Query: 94 RRSGQHPRYSSRIQASTKEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERH 153 RR + R Q ++++ L+++E + + E +L E L++ + E Sbjct: 697 RREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELE 756 Query: 154 REERRRQQQLDAER 167 ++++ +QQ AER Sbjct: 757 EKKKKEEQQRLAER 770 >gi|148762982 hypothetical protein LOC387640 [Homo sapiens] Length = 908 Score = 33.9 bits (76), Expect = 0.13 Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 22/130 (16%) Query: 14 PWYSHPVYARYWQHYHQAMAWMQSHHNAYRKAVESCFNLPWYLPSALLPQS-SYDNEAAY 72 P + H + + H+H+A QSHH + + +L S P+S S D+E++ Sbjct: 336 PHHHHHHHHHHHHHHHRAQPPQQSHHPPHHHRPQP------HLGS--FPESCSSDSESS- 386 Query: 73 PQSFYDHHVAWQDYPCSSSHFRRSGQHPRYSSRIQASTKEDQALSKEEEMETESDAEVEC 132 S+ DH D+ S S SS +S +E++ +EEE E E Sbjct: 387 --SYSDHAANDSDFGSSLSS----------SSNSVSSEEEEEEGEEEEEEEEEEGGSGAS 434 Query: 133 DLSNMEITEE 142 D S + EE Sbjct: 435 DSSEVSSEEE 444 >gi|153085395 histone deacetylase 4 [Homo sapiens] Length = 1084 Score = 33.5 bits (75), Expect = 0.17 Identities = 24/125 (19%), Positives = 55/125 (44%), Gaps = 17/125 (13%) Query: 111 KEDQALSKEEEMETESDAEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDS 170 ++ + LS++ E + + + ++ M+ +EL ++ + ERHR+E+ ++Q ++L Sbjct: 95 RQHEQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQ 154 Query: 171 YVNADHDLYCNTRRSVEAPTERPGERRQAEMKRLYGDSAAKIQAMEAAVQLSFDKHCDRK 230 N + + S A TE + ++ + + + A+ HC Sbjct: 155 LKNKE-----KGKESAVASTEVKMKLQEFVLNK------------KKALAHRNLNHCISS 197 Query: 231 QPKYW 235 P+YW Sbjct: 198 DPRYW 202 >gi|8923421 seryl-tRNA synthetase 2 isoform b precursor [Homo sapiens] Length = 518 Score = 33.5 bits (75), Expect = 0.17 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 7/88 (7%) Query: 76 FYDHHVAWQDYP----CSSSHFR---RSGQHPRYSSRIQASTKEDQALSKEEEMETESDA 128 F DH VA++D P CSS+ +R +GQ PR R+ TK + +E S Sbjct: 308 FMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQL 367 Query: 129 EVECDLSNMEITEELRQYFAETERHREE 156 E MEI EL +F + +E Sbjct: 368 LEEFLSLQMEILTELGLHFRVLDMPTQE 395 >gi|225579074 seryl-tRNA synthetase 2 isoform a precursor [Homo sapiens] Length = 520 Score = 33.5 bits (75), Expect = 0.17 Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 7/88 (7%) Query: 76 FYDHHVAWQDYP----CSSSHFR---RSGQHPRYSSRIQASTKEDQALSKEEEMETESDA 128 F DH VA++D P CSS+ +R +GQ PR R+ TK + +E S Sbjct: 310 FMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQL 369 Query: 129 EVECDLSNMEITEELRQYFAETERHREE 156 E MEI EL +F + +E Sbjct: 370 LEEFLSLQMEILTELGLHFRVLDMPTQE 397 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.126 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,273,628 Number of Sequences: 37866 Number of extensions: 402778 Number of successful extensions: 3145 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 67 Number of HSP's successfully gapped in prelim test: 194 Number of HSP's that attempted gapping in prelim test: 2516 Number of HSP's gapped (non-prelim): 716 length of query: 242 length of database: 18,247,518 effective HSP length: 99 effective length of query: 143 effective length of database: 14,498,784 effective search space: 2073326112 effective search space used: 2073326112 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.